pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/187-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of peptide secretion GO:0002792 6 5 3,000 1,173E-10 2,697E-07 GO:0046676|negative regulation of insulin secretion, ! regulation of protein export from nucleus GO:0046825 6 6 3,000 3,512E-10 4,039E-07 ! organ growth GO:0035265 11 7 3,000 8,181E-10 6,272E-07 ! regulation of growth hormone secretion GO:0060123 11 7 3,000 8,181E-10 4,704E-07 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 3,000 1,634E-09 7,514E-07 ! cellular response to hormone stimulus GO:0032870 109 74 5,000 1,602E-08 6,142E-06 ! negative regulation of hormone secretion GO:0046888 20 15 3,000 3,149E-08 1,035E-05 ! positive regulation of hormone secretion GO:0046887 24 17 3,000 5,472E-08 1,573E-05 ! regulation of insulin secretion GO:0050796 26 21 3,000 1,367E-07 3,494E-05 ! barbed-end actin filament capping GO:0051016 33 22 3,000 1,668E-07 3,837E-05 GO:0051693|actin filament capping, ! activation of MAPK activity GO:0000187 84 59 4,000 2,213E-07 4,628E-05 ! negative regulation of actin filament depolymerization GO:0030835 36 25 3,000 2,87E-07 5,502E-05 ! negative regulation of actin filament polymerization GO:0030837 36 25 3,000 2,87E-07 5,078E-05 ! regulation of peptide secretion GO:0002791 34 25 3,000 2,87E-07 4,716E-05 ! negative regulation of protein polymerization GO:0032272 38 26 3,000 3,387E-07 5,193E-05 ! regulation of actin filament depolymerization GO:0030834 39 27 3,000 3,969E-07 5,706E-05 ! negative regulation of protein complex assembly GO:0031333 42 28 3,000 4,623E-07 6,255E-05 ! triglyceride metabolic process GO:0006641 34 28 3,000 4,623E-07 5,907E-05 ! DNA damage checkpoint GO:0000077 53 31 3,000 7,07E-07 8,558E-05 ! negative regulation of secretion GO:0051048 49 31 3,000 7,07E-07 8,13E-05 ! neutral lipid metabolic process GO:0006638 41 32 3,000 8,066E-07 8,834E-05 GO:0006639|acylglycerol metabolic process, ! carbohydrate homeostasis GO:0033500 39 33 3,000 9,164E-07 9,58E-05 GO:0042593|glucose homeostasis, ! DNA integrity checkpoint GO:0031570 57 34 3,000 1,037E-06 1,037E-04 ! glycerol ether metabolic process GO:0006662 44 34 3,000 1,037E-06 9,936E-05 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 1,169E-06 1,075E-04 ! regulation of hormone secretion GO:0046883 48 36 3,000 1,313E-06 1,161E-04 ! organic ether metabolic process GO:0018904 46 36 3,000 1,313E-06 1,118E-04 ! hormone-mediated signaling GO:0009755 49 36 3,000 1,313E-06 1,078E-04 ! detection of bacterium GO:0016045 10 10 2,000 1,317E-06 1,044E-04 ! positive regulation of MAP kinase activity GO:0043406 121 85 4,000 1,389E-06 1,065E-04 ! negative regulation of protein complex disassembly GO:0043242 67 39 3,000 1,824E-06 1,353E-04 ! regulation of actin filament polymerization GO:0030833 59 40 3,000 2,023E-06 1,454E-04 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 2,47E-06 1,721E-04 ! regulation of protein complex disassembly GO:0043244 77 46 3,000 3,577E-06 2,42E-04 ! regulation of protein polymerization GO:0032271 71 47 3,000 3,903E-06 2,565E-04 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 3,000 4,251E-06 2,716E-04 ! regulation of intracellular transport GO:0032386 78 49 3,000 4,621E-06 2,873E-04 ! regulation of actin filament length GO:0030832 72 50 3,000 5,015E-06 3,035E-04 ! negative regulation of cytoskeleton organization GO:0051494 84 50 3,000 5,015E-06 2,957E-04 ! regulation of multicellular organism growth GO:0040014 65 50 3,000 5,015E-06 2,884E-04 ! positive regulation of secretion GO:0051047 71 51 3,000 5,433E-06 3,048E-04 ! regulation of cellular component size GO:0032535 74 52 3,000 5,876E-06 3,218E-04 ! negative regulation of immune response GO:0050777 28 16 2,000 6,087E-06 3,256E-04 ! detection of biotic stimulus GO:0009595 19 16 2,000 6,087E-06 3,182E-04 ! regulation of protein complex assembly GO:0043254 81 54 3,000 6,841E-06 3,497E-04 ! DNA damage response, signal transduction GO:0042770 96 56 3,000 7,919E-06 3,96E-04 ! multicellular organism reproduction GO:0032504 83 57 3,000 8,503E-06 4,161E-04 GO:0048609|reproductive process in a multicellular organism, ! cell cycle checkpoint GO:0000075 108 64 3,000 1,352E-05 6,478E-04 ! regulation of actin cytoskeleton organization GO:0032956 97 64 3,000 1,352E-05 6,346E-04 ! regulation of actin filament-based process GO:0032970 99 66 3,000 1,529E-05 7,031E-04 ! lymphocyte proliferation GO:0046651 36 23 2,000 1,904E-05 8,586E-04 ! steroid biosynthetic process GO:0006694 94 71 3,000 2,044E-05 9,04E-04 ! negative regulation of organelle organization GO:0010639 115 72 3,000 2,161E-05 9,376E-04 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 2,172E-05 9,253E-04 ! negative regulation of transport GO:0051051 116 73 3,000 2,282E-05 9,543E-04 ! leukocyte proliferation GO:0070661 39 25 2,000 2,465E-05 1,012E-03 GO:0032943|mononuclear cell proliferation, ! regulation of protein transport GO:0051223 114 76 3,000 2,677E-05 1,08E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of protein localization GO:0032880 132 85 3,000 4,162E-05 1,65E-03 ! porphyrin catabolic process GO:0006787 12 5 1,000 5,083E-05 1,981E-03 GO:0033015|tetrapyrrole catabolic process, ! hormone metabolic process GO:0042445 121 90 3,000 5,209E-05 1,997E-03 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 5,773E-05 2,177E-03 ! regulation of cytoskeleton organization GO:0051493 154 93 3,000 5,923E-05 2,197E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 6,322E-05 2,308E-03 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 6,706E-05 2,41E-03 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 3,000 7,562E-05 2,676E-03 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,064E-04 3,709E-03 ! positive regulation of isotype switching GO:0045830 15 7 1,000 1,064E-04 3,653E-03 GO:0045911|positive regulation of DNA recombination, ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 1,064E-04 3,6E-03 ! regulation of JNK cascade GO:0046328 58 41 2,000 1,114E-04 3,712E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 2,000 1,197E-04 3,935E-03 ! response to insulin stimulus GO:0032868 63 43 2,000 1,285E-04 4,164E-03 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 1,417E-04 4,526E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,417E-04 4,464E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,417E-04 4,404E-03 ! regulation of translational initiation GO:0006446 64 45 2,000 1,473E-04 4,518E-03 ! negative regulation of immune system process GO:0002683 73 47 2,000 1,678E-04 5,078E-03 ! SMAD protein nuclear translocation GO:0007184 15 9 1,000 1,819E-04 5,434E-03 ! motor axon guidance GO:0008045 14 9 1,000 1,819E-04 5,364E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 1,000 1,819E-04 5,296E-03 GO:0002820|negative regulation of adaptive immune response, ! B cell proliferation GO:0042100 14 10 1,000 2,271E-04 6,528E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,271E-04 6,447E-03 ! positive regulation of JNK cascade GO:0046330 14 10 1,000 2,271E-04 6,369E-03 ! detection of external stimulus GO:0009581 66 54 2,000 2,539E-04 7,035E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 2,771E-04 7,588E-03 GO:0000725|recombinational repair, ! T cell proliferation GO:0042098 20 11 1,000 2,771E-04 7,498E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 1,000 2,771E-04 7,411E-03 ! focal adhesion formation GO:0048041 24 11 1,000 2,771E-04 7,326E-03 ! regulation of isotype switching GO:0045191 19 11 1,000 2,771E-04 7,243E-03 ! protein-chromophore linkage GO:0018298 13 11 1,000 2,771E-04 7,161E-03 ! germ cell migration GO:0008354 18 11 1,000 2,771E-04 7,082E-03 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 2,828E-04 7,148E-03 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 2,98E-04 7,451E-03 ! regulation of cellular response to stress GO:0080135 85 61 2,000 3,643E-04 9,009E-03 ! regulation of MAPKKK cascade GO:0043408 101 65 2,000 4,393E-04 0,01074953 ! activation of MAPKK activity GO:0000186 21 14 1,000 4,565E-04 0,01105249 ! DNA unwinding during replication GO:0006268 21 14 1,000 4,565E-04 0,01093736 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 4,565E-04 0,0108246 ! patterning of blood vessels GO:0001569 24 16 1,000 6,003E-04 0,0140877 ! DNA duplex unwinding GO:0032508 25 17 1,000 6,793E-04 0,01578192 GO:0032392|DNA geometric change, ! cell-substrate junction assembly GO:0007044 39 17 1,000 6,793E-04 0,0156241 ! heme metabolic process GO:0042168 27 17 1,000 6,793E-04 0,01546941 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 1,000 6,793E-04 0,01531775 GO:0002712|regulation of B cell mediated immunity, ! regulation of immunoglobulin production GO:0002637 25 17 1,000 6,793E-04 0,01516903 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 8,517E-04 0,01883484 ! detection of stimulus GO:0051606 108 82 2,000 8,671E-04 0,01899344 ! positive regulation of B cell activation GO:0050871 31 20 1,000 9,449E-04 0,02050305 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 9,625E-04 0,02068887 ! skeletal muscle tissue development GO:0007519 123 87 2,000 1,03E-03 0,02192725 GO:0060538|skeletal muscle organ development, ! regulation of DNA recombination GO:0000018 40 21 1,000 1,043E-03 0,02200571 ! platelet activation GO:0030168 28 21 1,000 1,043E-03 0,02180565 ! porphyrin metabolic process GO:0006778 35 21 1,000 1,043E-03 0,02160921 GO:0033013|tetrapyrrole metabolic process, ! protein import into nucleus, translocation GO:0000060 36 22 1,000 1,146E-03 0,02352384 ! initiation of viral infection GO:0019059 42 24 1,000 1,365E-03 0,02777722 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 1,481E-03 0,02988455 ! regulation of translation GO:0006417 151 100 2,000 1,539E-03 0,0307762 ! Ras protein signal transduction GO:0007265 162 100 2,000 1,539E-03 0,03051088 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,602E-03 0,03149923 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 1,602E-03 0,03123229 ! respiratory gaseous exchange GO:0007585 47 27 1,000 1,728E-03 0,0333991 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 1,728E-03 0,03312078 ! cofactor catabolic process GO:0051187 45 27 1,000 1,728E-03 0,03284705 ! cell junction assembly GO:0034329 56 28 1,000 1,858E-03 0,03503313 ! regulation of B cell activation GO:0050864 42 28 1,000 1,858E-03 0,03474831 ! protein targeting to membrane GO:0006612 53 29 1,000 1,993E-03 0,03696781 ! ceramide metabolic process GO:0006672 43 30 1,000 2,132E-03 0,03923477 ! response to heat GO:0009408 41 30 1,000 2,132E-03 0,03892339 ! mammary gland development GO:0030879 57 31 1,000 2,276E-03 0,04122055 ! meiosis I GO:0007127 52 32 1,000 2,424E-03 0,04356211 ! cell junction organization GO:0034330 63 33 1,000 2,577E-03 0,04594668 ! sphingoid metabolic process GO:0046519 47 33 1,000 2,577E-03 0,04559325 ! neuron migration GO:0001764 46 34 1,000 2,734E-03 0,04800366 ! pigment metabolic process GO:0042440 61 35 1,000 2,896E-03 0,05045437 ! protein homooligomerization GO:0051260 52 35 1,000 2,896E-03 0,05007502 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 3,585E-03 0,06154062 ! double-strand break repair GO:0006302 67 40 1,000 3,769E-03 0,06420705 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 3,956E-03 0,06690681 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 4,148E-03 0,06963884 ! regulation of cell shape GO:0008360 78 42 1,000 4,148E-03 0,06913421 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 4,344E-03 0,07188124 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 4,344E-03 0,0713678 ! regulation of adaptive immune response GO:0002819 72 46 1,000 4,958E-03 0,08086962 ! viral infectious cycle GO:0019058 71 47 1,000 5,171E-03 0,08374821 ! response to temperature stimulus GO:0009266 62 48 1,000 5,388E-03 0,08665335 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 5,609E-03 0,08958418 ! germ cell development GO:0007281 68 49 1,000 5,609E-03 0,08896636 ! heterocycle catabolic process GO:0046700 72 49 1,000 5,609E-03 0,088357 ! positive regulation of cell migration GO:0030335 92 51 1,000 6,063E-03 0,09486981 ! sphingolipid metabolic process GO:0006665 72 52 1,000 6,297E-03 0,0978569 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 7,271E-03 0,11223877 ! positive regulation of cell motion GO:0051272 99 56 1,000 7,271E-03 0,11149051 ! membrane lipid metabolic process GO:0006643 79 57 1,000 7,525E-03 0,11461443 ! viral reproductive process GO:0022415 87 58 1,000 7,782E-03 0,11775725 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 1,000 8,309E-03 0,12490807 ! meiosis GO:0007126 96 61 1,000 8,578E-03 0,12811923 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 8,578E-03 0,12729266 ! negative regulation of ligase activity GO:0051352 91 61 1,000 8,578E-03 0,12647668 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 8,578E-03 0,1256711 ! respiratory tube development GO:0030323 99 62 1,000 8,852E-03 0,12885278 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 8,852E-03 0,12804238 ! meiotic cell cycle GO:0051321 97 62 1,000 8,852E-03 0,12724212 ! viral reproduction GO:0016032 92 63 1,000 9,129E-03 0,13041008 ! B cell activation GO:0042113 104 65 1,000 9,694E-03 0,13763673 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 9,694E-03 0,13679233 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 9,694E-03 0,13595823 ! protein oligomerization GO:0051259 100 65 1,000 9,694E-03 0,13513424 ! cell-substrate adhesion GO:0031589 121 66 1,000 9,983E-03 0,13831872 ! axon guidance GO:0007411 99 66 1,000 9,983E-03 0,13749046 ! regulation of immune effector process GO:0002697 101 66 1,000 9,983E-03 0,13667207 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 1,000 0,01027539 0,13984264 ! cytosolic calcium ion homeostasis GO:0051480 107 68 1,000 0,01057157 0,14302709 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,01087151 0,14622493 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,01087151 0,14537478 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,01117519 0,14857189 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,0113894 0,15054958 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,0113894 0,14968929 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,0113894 0,14883879 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,0113894 0,14799789 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,0113894 0,14716644 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0113894 0,14634428 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,0113894 0,14553126 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,0113894 0,14472722 ! sleep GO:0030431 11 5 0,000 0,0113894 0,14393201 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0113894 0,1431455 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,0113894 0,14236754 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,0113894 0,14159798 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,0113894 0,1408367 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,0113894 0,14008356 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,0113894 0,13933844 ! tongue development GO:0043586 6 5 0,000 0,0113894 0,1386012 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,0113894 0,13787172 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0113894 0,13714988 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,0113894 0,13643555 ! cobalt ion transport GO:0006824 9 5 0,000 0,0113894 0,13572863 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,0113894 0,135029 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,0113894 0,13433655 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,0113894 0,13365116 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,0113894 0,13297272 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,0113894 0,13230114 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,0113894 0,13163631 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,0113894 0,13097813 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,0113894 0,1303265 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,0113894 0,12968132 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0113894 0,1290425 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0113894 0,12840993 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0113894 0,12778354 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,0113894 0,12716324 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,0113894 0,12654892 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0113894 0,12594051 ! malate metabolic process GO:0006108 7 5 0,000 0,0113894 0,12533793 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,0113894 0,12474108 ! behavioral response to pain GO:0048266 7 5 0,000 0,0113894 0,12414989 ! clathrin coat assembly GO:0048268 11 5 0,000 0,0113894 0,12356428 ! phototransduction, visible light GO:0007603 6 5 0,000 0,0113894 0,12298416 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0113894 0,12240947 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,0113894 0,12184012 ! mating behavior GO:0007617 6 5 0,000 0,0113894 0,12127605 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0113894 0,12071717 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,0113894 0,12016342 ! rhythmic behavior GO:0007622 12 5 0,000 0,0113894 0,11961473 ! copulation GO:0007620 7 5 0,000 0,0113894 0,11907103 ! glial cell fate commitment GO:0021781 12 5 0,000 0,0113894 0,11853225 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,0113894 0,11799832 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,0113894 0,11746918 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,0113894 0,11694476 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,0113894 0,11642501 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,0113894 0,11590985 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,0113894 0,11539924 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,0113894 0,1148931 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0113894 0,11439138 ! response to protozoan GO:0001562 9 5 0,000 0,0113894 0,11389403 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,0113894 0,11340098 ! lymph vessel development GO:0001945 7 5 0,000 0,0113894 0,11291218 ! endochondral ossification GO:0001958 12 5 0,000 0,0113894 0,11242758 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,0113894 0,11194712 ! parathyroid gland development GO:0060017 8 5 0,000 0,0113894 0,11147075 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,0113894 0,11099842 ! anagen GO:0042640 6 5 0,000 0,0113894 0,11053007 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,0113894 0,11006566 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,0113894 0,10960513 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,0113894 0,10914844 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,0113894 0,10869555 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,0113894 0,10824639 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,0113894 0,10780093 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,0113894 0,10735913 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,0113894 0,10692092 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,0113894 0,10648629 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,0113894 0,10605517 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,0113894 0,10562753 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,0113894 0,10520332 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,0113894 0,10478251 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,0113894 0,10436505 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,0113894 0,1039509 ! ovulation GO:0030728 6 5 0,000 0,0113894 0,10354003 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,0113894 0,10313239 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,0113894 0,10272795 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,0113894 0,10232667 ! response to pH GO:0009268 9 5 0,000 0,0113894 0,10192851 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,0113894 0,10153344 ! proline biosynthetic process GO:0006561 6 5 0,000 0,0113894 0,10114142 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0113894 0,10075241 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,0113894 0,10036639 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0113894 0,09998331 ! polyol catabolic process GO:0046174 7 5 0,000 0,0113894 0,09960314 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0113894 0,09922586 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0113894 0,09885142 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0113894 0,0984798 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,0113894 0,09811096 ! nerve growth factor processing GO:0032455 7 5 0,000 0,0113894 0,09774488 ! urea metabolic process GO:0019627 6 5 0,000 0,0113894 0,09738151 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,0113894 0,09702084 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0113894 0,09666283 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,0113894 0,09630745 ! neutrophil activation GO:0042119 5 5 0,000 0,0113894 0,09595468 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,0113894 0,09560448 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,0113894 0,09525682 ! response to food GO:0032094 5 5 0,000 0,0113894 0,09491169 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,0113894 0,09456905 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0113894 0,09422887 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,0113894 0,09389113 ! forebrain neuron development GO:0021884 7 5 0,000 0,0113894 0,09355581 ! melanosome organization GO:0032438 7 5 0,000 0,0113894 0,09322287 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,0113894 0,09289229 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0113894 0,09256405 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,0113894 0,09223812 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0113894 0,09191448 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,0113894 0,0915931 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,0113894 0,09127396 ! nucleoside transport GO:0015858 6 5 0,000 0,0113894 0,09095704 ! nucleoside salvage GO:0043174 7 5 0,000 0,0113894 0,09064231 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,0113894 0,09032975 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0113894 0,09001934 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,0113894 0,08971105 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,0113894 0,08940487 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0113894 0,08910077 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,0113894 0,08879873 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0113894 0,08849874 ! depyrimidination GO:0045008 8 5 0,000 0,0113894 0,08820076 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,0113894 0,08790479 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,0113894 0,08761079 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,0113894 0,08731876 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0113894 0,08702866 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,0113894 0,08674049 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,0113894 0,08645421 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,0113894 0,08616982 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,0113894 0,0858873 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,0113894 0,08560662 ! monocyte differentiation GO:0030224 8 5 0,000 0,0113894 0,08532777 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0113894 0,08505074 ! centrosome duplication GO:0051298 5 5 0,000 0,0113894 0,08477549 ! response to UV-C GO:0010225 6 5 0,000 0,0113894 0,08450202 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,0113894 0,08423031 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,0113894 0,08396034 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,0113894 0,0836921 ! regulation of dendrite development GO:0050773 12 5 0,000 0,0113894 0,08342556 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,0113894 0,08316072 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0113894 0,08289755 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,0113894 0,08263605 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,0113894 0,08237618 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,0113894 0,08211795 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,0113894 0,08186133 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,0113894 0,08160631 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,0113894 0,08135288 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,0113894 0,08110101 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0113894 0,0808507 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,0113894 0,08060193 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0113894 0,08035468 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0113894 0,08010895 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,0113894 0,07986472 ! neural tube patterning GO:0021532 6 5 0,000 0,0113894 0,07962197 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,0113894 0,07938069 ! histone demethylation GO:0016577 9 5 0,000 0,0113894 0,07914087 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0113894 0,07890249 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0113894 0,07866555 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,0113894 0,07843002 ! enteric nervous system development GO:0048484 8 5 0,000 0,0113894 0,0781959 ! establishment of planar polarity GO:0001736 6 5 0,000 0,0113894 0,07796317 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,0113894 0,07773183 ! muscle cell proliferation GO:0033002 8 5 0,000 0,0113894 0,07750185 ! transcription termination GO:0006353 8 5 0,000 0,0113894 0,07727323 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,0113894 0,07704596 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,0113894 0,07682002 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,0113894 0,0765954 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,0113894 0,07637209 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,0113894 0,07615008 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0113894 0,07592935 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0113894 0,0757099 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,0113894 0,07549172 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,0113894 0,07527479 ! apical protein localization GO:0045176 6 5 0,000 0,0113894 0,0750591 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,0113894 0,07484465 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,0113894 0,07463141 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0113894 0,07441939 GO:0006681|galactosylceramide metabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,0113894 0,07420857 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,0113894 0,07399895 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,0113894 0,0737905 ! glial cell migration GO:0008347 10 5 0,000 0,0113894 0,07358322 ! determination of adult lifespan GO:0008340 8 5 0,000 0,0113894 0,07337711 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,0113894 0,07317214 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0113894 0,07296832 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0113894 0,07276563 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,0113894 0,07256406 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,0113894 0,07236361 ! neural plate development GO:0001840 6 5 0,000 0,0113894 0,07216426 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,0113894 0,07196601 ! regulation of sensory perception GO:0051931 6 5 0,000 0,0113894 0,07176884 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,0113894 0,07157275 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,0113894 0,07137773 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,0113894 0,07118377 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,0113894 0,07099086 ! sensory cilium assembly GO:0035058 6 5 0,000 0,0113894 0,07079899 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,0113894 0,07060816 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0113894 0,07041835 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,0113894 0,07022956 ! spindle assembly GO:0051225 5 5 0,000 0,0113894 0,07004178 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,0113894 0,069855 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,0113894 0,06966922 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,0113894 0,06948442 ! organ regeneration GO:0031100 7 5 0,000 0,0113894 0,0693006 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,0113894 0,06911775 ! carnitine metabolic process GO:0009437 5 5 0,000 0,0113894 0,06893586 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,0113894 0,06875493 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,0113894 0,06857494 GO:0055081|anion homeostasis, ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,0114826 0,06895558 ! response to hypoxia GO:0001666 132 72 1,000 0,01179373 0,07063952 ! tube morphogenesis GO:0035239 118 73 1,000 0,01210855 0,07233677 ! response to oxygen levels GO:0070482 137 74 1,000 0,01242704 0,07404713 ! protein import into nucleus GO:0006606 118 74 1,000 0,01242704 0,07385579 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,01242704 0,07366544 ! blood coagulation GO:0007596 116 75 1,000 0,01274919 0,07538082 GO:0050817|coagulation, ! regulation of ligase activity GO:0051340 114 75 1,000 0,01274919 0,07518754 ! nuclear import GO:0051170 121 75 1,000 0,01274919 0,07499524 ! response to unfolded protein GO:0006986 99 76 1,000 0,01307498 0,07671547 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,01307498 0,07652026 ! gland development GO:0048732 148 77 1,000 0,0134044 0,07824903 ! tRNA transcription GO:0009304 11 6 0,000 0,01365206 0,079493 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01365206 0,07929226 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01365206 0,07909253 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01365206 0,0788938 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01365206 0,07869607 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01365206 0,07849933 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01365206 0,07830357 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01365206 0,07810879 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01365206 0,07791497 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01365206 0,07772211 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01365206 0,07753021 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01365206 0,07733924 ! prostate gland development GO:0030850 9 6 0,000 0,01365206 0,07714922 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01365206 0,07696013 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01365206 0,07677196 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01365206 0,07658472 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01365206 0,07639838 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01365206 0,07621295 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01365206 0,07602841 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01365206 0,07584477 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01365206 0,07566201 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01365206 0,07548013 ! neuron adhesion GO:0007158 9 6 0,000 0,01365206 0,07529912 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01365206 0,07511898 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01365206 0,0749397 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01365206 0,07476127 ! signal peptide processing GO:0006465 8 6 0,000 0,01365206 0,07458369 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01365206 0,07440695 ! mRNA stabilization GO:0048255 15 6 0,000 0,01365206 0,07423105 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01365206 0,07405597 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01365206 0,07388173 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01365206 0,07370829 ! opsonization GO:0008228 8 6 0,000 0,01365206 0,07353568 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01365206 0,07336386 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01365206 0,07319285 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01365206 0,07302264 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01365206 0,07285321 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01365206 0,07268457 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01365206 0,07251671 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01365206 0,07234962 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01365206 0,0721833 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01365206 0,07201774 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01365206 0,07185294 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01365206 0,07168889 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01365206 0,07152559 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01365206 0,07136303 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01365206 0,07120121 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01365206 0,07104012 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01365206 0,07087976 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01365206 0,07072012 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01365206 0,0705612 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01365206 0,07040299 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01365206 0,07024549 ! thymic T cell selection GO:0045061 12 6 0,000 0,01365206 0,07008869 ! protein lipoylation GO:0009249 10 6 0,000 0,01365206 0,06993259 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01365206 0,06977719 ! pigment granule organization GO:0048753 11 6 0,000 0,01365206 0,06962247 ! drug transport GO:0015893 6 6 0,000 0,01365206 0,06946844 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01365206 0,06931508 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01365206 0,06916241 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01365206 0,0690104 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01365206 0,06885906 ! histidine metabolic process GO:0006547 6 6 0,000 0,01365206 0,06870839 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01365206 0,06855837 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01365206 0,06840901 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01365206 0,06826029 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01365206 0,06811222 ! adenohypophysis development GO:0021984 10 6 0,000 0,01365206 0,06796479 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01365206 0,067818 ! hyperosmotic response GO:0006972 8 6 0,000 0,01365206 0,06767184 ! microtubule nucleation GO:0007020 10 6 0,000 0,01365206 0,06752631 ! ER overload response GO:0006983 7 6 0,000 0,01365206 0,0673814 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01365206 0,06723712 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01365206 0,06709345 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01365206 0,06695039 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01365206 0,06680794 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01365206 0,0666661 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01365206 0,06652486 ! response to dietary excess GO:0002021 7 6 0,000 0,01365206 0,06638421 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01365206 0,06624416 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01365206 0,0661047 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01365206 0,06596583 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01365206 0,06582753 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01365206 0,06568982 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01365206 0,06555268 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01365206 0,06541611 ! neuron apoptosis GO:0051402 8 6 0,000 0,01365206 0,06528011 ! organic alcohol transport GO:0015850 9 6 0,000 0,01365206 0,06514468 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01365206 0,0650098 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01365206 0,06487548 ! male sex determination GO:0030238 9 6 0,000 0,01365206 0,06474172 ! carnitine transport GO:0015879 8 6 0,000 0,01365206 0,0646085 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01365206 0,06447584 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01365206 0,06434372 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01365206 0,06421213 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01365206 0,06408109 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01365206 0,06395058 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01365206 0,0638206 ! parturition GO:0007567 12 6 0,000 0,01365206 0,06369114 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01365206 0,06356221 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01365206 0,0634338 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01365206 0,06330591 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01365206 0,06317854 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01365206 0,06305167 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01365206 0,06292532 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01365206 0,06279947 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01365206 0,06267412 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01365206 0,06254927 ! macrophage differentiation GO:0030225 10 6 0,000 0,01365206 0,06242492 ! astrocyte development GO:0014002 14 6 0,000 0,01365206 0,06230106 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01365206 0,06217769 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01365206 0,06205481 ! interaction with symbiont GO:0051702 8 6 0,000 0,01365206 0,06193241 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01365206 0,0618105 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01365206 0,06168906 ! eating behavior GO:0042755 6 6 0,000 0,01365206 0,0615681 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01365206 0,06144762 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01365206 0,0613276 ! response to copper ion GO:0046688 9 6 0,000 0,01365206 0,06120806 ! DNA topological change GO:0006265 8 6 0,000 0,01365206 0,06108898 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01365206 0,06097036 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01365206 0,0608522 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01365206 0,06073449 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01365206 0,06061725 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01365206 0,06050045 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01365206 0,0603841 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01365206 0,0602682 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01365206 0,06015275 ! gas homeostasis GO:0033483 11 6 0,000 0,01365206 0,06003773 ! hair follicle maturation GO:0048820 7 6 0,000 0,01365206 0,05992316 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01365206 0,05980902 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01365206 0,05969531 ! Schwann cell development GO:0014044 14 6 0,000 0,01365206 0,05958204 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01365206 0,05946919 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01365206 0,05935677 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01365206 0,05924478 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01365206 0,05913321 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01365206 0,05902206 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01365206 0,05891132 ! histone ubiquitination GO:0016574 7 6 0,000 0,01365206 0,058801 ! regulation of meiosis GO:0040020 10 6 0,000 0,01365206 0,05869109 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01365206 0,05858159 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01365206 0,0584725 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01365206 0,05836382 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01365206 0,05825553 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01365206 0,05814765 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01365206 0,05804017 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01365206 0,05793309 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01365206 0,0578264 ! receptor internalization GO:0031623 9 6 0,000 0,01365206 0,0577201 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01365206 0,05761419 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01365206 0,05750867 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01365206 0,05740353 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01365206 0,05729878 ! protein deubiquitination GO:0016579 8 6 0,000 0,01365206 0,05719441 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01365206 0,05709042 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01365206 0,05698681 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01365206 0,05688357 ! axonal fasciculation GO:0007413 9 6 0,000 0,01365206 0,05678071 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01365206 0,05667822 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01365206 0,0565761 ! midbrain development GO:0030901 6 6 0,000 0,01365206 0,05647434 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01365206 0,05637295 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01365206 0,05627192 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01365206 0,05617126 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01365206 0,05607095 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01365206 0,055971 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01365206 0,05587141 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01365206 0,05577217 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01365206 0,05567329 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01365206 0,05557475 ! adult feeding behavior GO:0008343 6 6 0,000 0,01365206 0,05547656 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01365206 0,05537872 ! blastocyst growth GO:0001832 15 6 0,000 0,01365206 0,05528122 ! pigment granule transport GO:0051904 12 6 0,000 0,01365206 0,05518407 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01365206 0,05508725 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01365206 0,05499078 ! catecholamine transport GO:0051937 7 6 0,000 0,01365206 0,05489464 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01365206 0,05479884 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01365206 0,05470337 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01365206 0,05460823 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01365206 0,05451343 ! protein prenylation GO:0018342 10 6 0,000 0,01365206 0,05441895 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01365206 0,0543248 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01365206 0,05423097 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01365206 0,05413747 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01365206 0,05404429 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01365206 0,05395143 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,01373742 0,05419566 ! T cell activation GO:0042110 134 79 1,000 0,01407403 0,05542854 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,01441421 0,05667126 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 1,000 0,01441421 0,05657455 ! hemostasis GO:0007599 125 81 1,000 0,01475795 0,057825 ! response to protein stimulus GO:0051789 111 81 1,000 0,01475795 0,05772666 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01475795 0,05762865 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,01590966 0,06202072 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01590966 0,06191578 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01590966 0,06181119 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01590966 0,06170696 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01590966 0,06160307 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01590966 0,06149954 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01590966 0,06139635 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01590966 0,06129351 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01590966 0,06119101 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01590966 0,06108886 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01590966 0,06098704 ! reproductive behavior GO:0019098 12 7 0,000 0,01590966 0,06088557 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01590966 0,06078443 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01590966 0,06068363 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01590966 0,06058316 ! oligopeptide transport GO:0006857 11 7 0,000 0,01590966 0,06048302 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01590966 0,06038321 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01590966 0,06028373 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01590966 0,06018458 ! RNA methylation GO:0001510 11 7 0,000 0,01590966 0,06008576 ! pericardium development GO:0060039 8 7 0,000 0,01590966 0,05998726 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01590966 0,05988908 ! fibril organization GO:0043206 13 7 0,000 0,01590966 0,05979122 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01590966 0,05969368 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01590966 0,05959646 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01590966 0,05949956 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01590966 0,05940297 ! lipoprotein transport GO:0042953 9 7 0,000 0,01590966 0,05930669 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01590966 0,05921072 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01590966 0,05911507 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01590966 0,05901972 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01590966 0,05892468 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01590966 0,05882995 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01590966 0,05873552 ! chemosensory behavior GO:0007635 9 7 0,000 0,01590966 0,05864139 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01590966 0,05854756 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01590966 0,05845404 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01590966 0,05836081 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01590966 0,05826788 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01590966 0,05817524 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01590966 0,0580829 ! reflex GO:0060004 12 7 0,000 0,01590966 0,05799085 ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01590966 0,05789909 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01590966 0,05780762 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01590966 0,05771645 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01590966 0,05762555 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01590966 0,05753495 ! spinal cord patterning GO:0021511 7 7 0,000 0,01590966 0,05744463 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01590966 0,05735459 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01590966 0,05726483 ! adrenal gland development GO:0030325 17 7 0,000 0,01590966 0,05717535 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01590966 0,05708616 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01590966 0,05699724 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01590966 0,05690859 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01590966 0,05682023 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01590966 0,05673213 ! endosome organization GO:0007032 10 7 0,000 0,01590966 0,05664431 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01590966 0,05655676 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01590966 0,05646949 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01590966 0,05638248 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01590966 0,05629573 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01590966 0,05620926 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01590966 0,05612305 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01590966 0,0560371 ! galactose metabolic process GO:0006012 10 7 0,000 0,01590966 0,05595142 ! vesicle fusion GO:0006906 15 7 0,000 0,01590966 0,05586599 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01590966 0,05578083 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01590966 0,05569593 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01590966 0,05561129 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01590966 0,0555269 ! retinol metabolic process GO:0042572 9 7 0,000 0,01590966 0,05544277 ! behavioral fear response GO:0001662 13 7 0,000 0,01590966 0,05535889 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01590966 0,05527527 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01590966 0,0551919 ! rRNA modification GO:0000154 12 7 0,000 0,01590966 0,05510877 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01590966 0,0550259 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01590966 0,05494328 ! response to UV-B GO:0010224 11 7 0,000 0,01590966 0,05486091 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01590966 0,05477878 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01590966 0,0546969 ! intermediate filament organization GO:0045109 11 7 0,000 0,01590966 0,05461526 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01590966 0,05453387 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01590966 0,05445272 ! fibrinolysis GO:0042730 9 7 0,000 0,01590966 0,05437181 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01590966 0,05429114 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01590966 0,05421071 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01590966 0,05413051 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01590966 0,05405056 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01590966 0,05397084 ! response to tropane GO:0014073 13 7 0,000 0,01590966 0,05389135 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01590966 0,0538121 ! melanosome localization GO:0032400 10 7 0,000 0,01590966 0,05373308 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01590966 0,05365429 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01590966 0,05357573 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01590966 0,05349741 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01590966 0,05341931 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01590966 0,05334144 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01590966 0,05326379 ! mast cell activation GO:0045576 9 7 0,000 0,01590966 0,05318638 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01590966 0,05310918 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01590966 0,05303221 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01590966 0,05295547 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01590966 0,05287894 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01590966 0,05280264 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01590966 0,05272655 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01590966 0,05265069 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01590966 0,05257504 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01590966 0,05249961 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01590966 0,05242439 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01590966 0,05234939 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01590966 0,05227461 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01590966 0,05220004 ! response to tumor cell GO:0002347 12 7 0,000 0,01590966 0,05212568 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01590966 0,05205153 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01590966 0,05197759 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01590966 0,05190387 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01590966 0,05183035 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01590966 0,05175704 ! diuresis GO:0030146 12 7 0,000 0,01590966 0,05168394 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01590966 0,05161104 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01590966 0,05153835 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01590966 0,05146586 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01590966 0,05139358 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01590966 0,0513215 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01590966 0,05124962 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01590966 0,05117794 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01590966 0,05110646 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01590966 0,05103518 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01590966 0,0509641 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01590966 0,05089322 ! lymph node development GO:0048535 9 7 0,000 0,01590966 0,05082254 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01590966 0,05075205 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01590966 0,05068175 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01590966 0,05061165 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01590966 0,05054175 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01590966 0,05047204 ! ATP catabolic process GO:0006200 10 7 0,000 0,01590966 0,05040252 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01590966 0,05033319 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01590966 0,05026405 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01590966 0,0501951 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01590966 0,05012634 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01590966 0,05005777 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01590966 0,04998938 ! muscle adaptation GO:0043500 12 7 0,000 0,01590966 0,04992118 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01590966 0,04985317 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01590966 0,04978534 ! retina homeostasis GO:0001895 9 7 0,000 0,01590966 0,0497177 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01590966 0,04965024 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01590966 0,04958296 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01590966 0,04951587 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01590966 0,04944895 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01590966 0,04938222 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01590966 0,04931567 ! female pregnancy GO:0007565 130 87 1,000 0,01689403 0,05229645 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01816223 0,05614668 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01816223 0,05607132 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01816223 0,05599615 ! axon extension GO:0048675 11 8 0,000 0,01816223 0,05592119 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01816223 0,05584643 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01816223 0,05577187 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01816223 0,05569751 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01816223 0,05562334 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01816223 0,05554938 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01816223 0,05547561 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01816223 0,05540203 ! phosphate transport GO:0006817 10 8 0,000 0,01816223 0,05532865 ! N-glycan processing GO:0006491 12 8 0,000 0,01816223 0,05525546 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01816223 0,05518247 ! UTP metabolic process GO:0046051 8 8 0,000 0,01816223 0,05510967 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01816223 0,05503706 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01816223 0,05496465 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01816223 0,05489242 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01816223 0,05482038 ! succinate metabolic process GO:0006105 14 8 0,000 0,01816223 0,05474853 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01816223 0,05467687 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01816223 0,0546054 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01816223 0,05453411 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01816223 0,05446301 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01816223 0,0543921 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01816223 0,05432137 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01816223 0,05425082 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01816223 0,05418046 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01816223 0,05411027 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01816223 0,05404027 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01816223 0,05397045 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01816223 0,05390081 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01816223 0,05383135 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01816223 0,05376207 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01816223 0,05369297 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01816223 0,05362405 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01816223 0,0535553 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01816223 0,05348672 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01816223 0,05341833 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01816223 0,0533501 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01816223 0,05328206 ! melanin metabolic process GO:0006582 12 8 0,000 0,01816223 0,05321418 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01816223 0,05314648 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01816223 0,05307895 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01816223 0,05301159 ! macrophage activation GO:0042116 12 8 0,000 0,01816223 0,0529444 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01816223 0,05287738 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01816223 0,05281053 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01816223 0,05274385 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01816223 0,05267734 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01816223 0,052611 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01816223 0,05254482 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01816223 0,05247881 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01816223 0,05241296 ! ruffle organization GO:0031529 11 8 0,000 0,01816223 0,05234728 ! osteoblast development GO:0002076 13 8 0,000 0,01816223 0,05228177 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01816223 0,05221641 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01816223 0,05215123 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01816223 0,0520862 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01816223 0,05202133 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01816223 0,05195663 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01816223 0,05189209 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01816223 0,05182771 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01816223 0,05176348 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01816223 0,05169942 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01816223 0,05163551 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01816223 0,05157177 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01816223 0,05150818 ! segment specification GO:0007379 10 8 0,000 0,01816223 0,05144474 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,01816223 0,05138147 ! cellular extravasation GO:0045123 11 8 0,000 0,01816223 0,05131834 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01816223 0,05125538 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01816223 0,05119256 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01816223 0,0511299 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01816223 0,0510674 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01816223 0,05100504 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01816223 0,05094284 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01816223 0,05088079 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01816223 0,05081889 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01816223 0,05075715 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01816223 0,05069555 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01816223 0,0506341 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01816223 0,0505728 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01816223 0,05051165 ! icosanoid secretion GO:0032309 12 8 0,000 0,01816223 0,05045064 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01816223 0,05038978 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01816223 0,05032907 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01816223 0,05026851 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01816223 0,05020809 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01816223 0,05014782 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01816223 0,05008769 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01816223 0,0500277 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01816223 0,04996786 ! sterol catabolic process GO:0016127 9 8 0,000 0,01816223 0,04990816 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01816223 0,04984861 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01816223 0,04978919 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01816223 0,04972992 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01816223 0,04967079 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01816223 0,04961179 ! prophase GO:0051324 11 8 0,000 0,01816223 0,04955294 ! S phase GO:0051320 8 8 0,000 0,01816223 0,04949423 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01816223 0,04943566 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,01816223 0,04937722 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01816223 0,04931893 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01816223 0,04926077 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01816223 0,04920275 ! hormone catabolic process GO:0042447 13 8 0,000 0,01816223 0,04914486 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01816223 0,04908711 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01816223 0,0490295 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01816223 0,04897202 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01816223 0,04891467 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01816223 0,04885746 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01816223 0,04880039 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01816223 0,04874344 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01816223 0,04868663 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01816223 0,04862995 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01816223 0,04857341 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01816223 0,04851699 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01816223 0,04846071 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01816223 0,04840456 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01816223 0,04834853 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01816223 0,04829264 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01816223 0,04823687 ! response to virus GO:0009615 122 91 1,000 0,018387 0,04877751 ! DNA recombination GO:0006310 146 92 1,000 0,01876871 0,04973275 ! angiogenesis GO:0001525 149 95 1,000 0,01993386 0,05275936 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02040977 0,05395687 ! regulation of developmental growth GO:0048638 13 9 0,000 0,02040977 0,05389492 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,02040977 0,05383311 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02040977 0,05377145 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02040977 0,05370992 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02040977 0,05364854 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02040977 0,0535873 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02040977 0,05352619 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02040977 0,05346523 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02040977 0,05340441 ! GTP metabolic process GO:0046039 9 9 0,000 0,02040977 0,05334372 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02040977 0,05328317 ! social behavior GO:0035176 14 9 0,000 0,02040977 0,05322276 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02040977 0,05316248 ! artery development GO:0060840 19 9 0,000 0,02040977 0,05310234 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02040977 0,05304234 ! regulation of glycolysis GO:0006110 15 9 0,000 0,02040977 0,05298248 ! response to pain GO:0048265 16 9 0,000 0,02040977 0,05292274 ! protein complex disassembly GO:0043241 17 9 0,000 0,02040977 0,05286315 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02040977 0,05280368 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02040977 0,05274435 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02040977 0,05268515 ! lung alveolus development GO:0048286 17 9 0,000 0,02040977 0,05262609 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02040977 0,05256716 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02040977 0,05250836 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02040977 0,05244969 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02040977 0,05239115 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02040977 0,05233275 ! protein targeting to ER GO:0045047 19 9 0,000 0,02040977 0,05227447 ! T cell selection GO:0045058 18 9 0,000 0,02040977 0,05221632 ! endoderm development GO:0007492 12 9 0,000 0,02040977 0,0521583 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02040977 0,05210041 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02040977 0,05204265 ! arginine catabolic process GO:0006527 10 9 0,000 0,02040977 0,05198502 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02040977 0,05192751 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02040977 0,05187014 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02040977 0,05181288 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02040977 0,05175576 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02040977 0,05169876 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02040977 0,05164188 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02040977 0,05158514 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02040977 0,05152851 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02040977 0,05147201 ! mannose metabolic process GO:0006013 9 9 0,000 0,02040977 0,05141563 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02040977 0,05135938 ! receptor clustering GO:0043113 15 9 0,000 0,02040977 0,05130325 ! epithelial cell development GO:0002064 10 9 0,000 0,02040977 0,05124724 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02040977 0,05119136 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02040977 0,05113559 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02040977 0,05107995 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02040977 0,05102443 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02040977 0,05096903 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02040977 0,05091374 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02040977 0,05085858 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02040977 0,05080354 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02040977 0,05074862 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02040977 0,05069382 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02040977 0,05063913 ! DNA ligation GO:0006266 14 9 0,000 0,02040977 0,05058456 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02040977 0,05053011 ! response to amine stimulus GO:0014075 13 9 0,000 0,02040977 0,05047578 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02040977 0,05042156 ! erythrocyte development GO:0048821 11 9 0,000 0,02040977 0,05036746 ! renal water homeostasis GO:0003091 14 9 0,000 0,02040977 0,05031348 ! postreplication repair GO:0006301 11 9 0,000 0,02040977 0,05025961 ! mRNA cleavage GO:0006379 13 9 0,000 0,02040977 0,05020585 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02040977 0,05015221 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02040977 0,05009869 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02040977 0,05004528 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02040977 0,04999198 ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02040977 0,0499388 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02040977 0,04988573 ! acid secretion GO:0046717 14 9 0,000 0,02040977 0,04983277 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02040977 0,04977993 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02040977 0,0497272 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02040977 0,04967457 ! purine base metabolic process GO:0006144 18 9 0,000 0,02040977 0,04962206 ! oocyte differentiation GO:0009994 12 9 0,000 0,02040977 0,04956967 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02040977 0,04951738 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02040977 0,0494652 ! spleen development GO:0048536 15 9 0,000 0,02040977 0,04941313 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02040977 0,04936117 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02040977 0,04930932 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02040977 0,04925758 ! detection of calcium ion GO:0005513 13 9 0,000 0,02040977 0,04920595 ! blastocyst formation GO:0001825 12 9 0,000 0,02040977 0,04915442 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02040977 0,04910301 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02040977 0,0490517 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02040977 0,04900049 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02040977 0,0489494 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02040977 0,04889841 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02040977 0,04884753 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02040977 0,04879675 ! prepulse inhibition GO:0060134 14 9 0,000 0,02040977 0,04874608 ! embryonic placenta development GO:0001892 12 9 0,000 0,02040977 0,04869551 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02040977 0,04864505 ! insulin secretion GO:0030073 17 9 0,000 0,02040977 0,04859469 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02040977 0,04854444 ! response to nicotine GO:0035094 16 9 0,000 0,02040977 0,04849429 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02040977 0,04844424 ! nucleus localization GO:0051647 15 9 0,000 0,02040977 0,0483943 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02040977 0,04834446 ! localization within membrane GO:0051668 15 9 0,000 0,02040977 0,04829473 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,02072717 0,04899537 ! protein import GO:0017038 156 99 1,000 0,02153356 0,05084926 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,02194161 0,0517597 ! protein localization in organelle GO:0033365 161 100 1,000 0,02194161 0,05170667 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02265229 0,05332679 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02265229 0,05327227 ! neuron fate specification GO:0048665 11 10 0,000 0,02265229 0,05321785 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02265229 0,05316355 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02265229 0,05310935 ! thyroid gland development GO:0030878 19 10 0,000 0,02265229 0,05305527 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02265229 0,0530013 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02265229 0,05294744 ! synapsis GO:0007129 13 10 0,000 0,02265229 0,05289368 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02265229 0,05284004 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02265229 0,0527865 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02265229 0,05273307 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02265229 0,05267975 ! sulfate transport GO:0008272 12 10 0,000 0,02265229 0,05262654 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02265229 0,05257344 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02265229 0,05252044 ! androgen metabolic process GO:0008209 13 10 0,000 0,02265229 0,05246755 ! phospholipid efflux GO:0033700 16 10 0,000 0,02265229 0,05241477 ! hippocampus development GO:0021766 19 10 0,000 0,02265229 0,05236209 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,02265229 0,05230951 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02265229 0,05225705 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02265229 0,05220469 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02265229 0,05215243 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02265229 0,05210028 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02265229 0,05204823 ! pathogenesis GO:0009405 13 10 0,000 0,02265229 0,05199628 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02265229 0,05194444 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02265229 0,05189271 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02265229 0,05184107 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02265229 0,05178954 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02265229 0,05173811 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02265229 0,05168678 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02265229 0,05163556 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02265229 0,05158443 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02265229 0,05153341 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02265229 0,05148249 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02265229 0,05143166 ! response to X-ray GO:0010165 16 10 0,000 0,02265229 0,05138094 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02265229 0,05133032 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02265229 0,0512798 ! forebrain cell migration GO:0021885 17 10 0,000 0,02265229 0,05122938 ! lipid digestion GO:0044241 15 10 0,000 0,02265229 0,05117905 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02265229 0,05112883 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02265229 0,0510787 ! UV protection GO:0009650 14 10 0,000 0,02265229 0,05102867 ! entry into host cell GO:0030260 20 10 0,000 0,02265229 0,05097874 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02265229 0,05092891 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02265229 0,05087918 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02265229 0,05082954 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02265229 0,05078 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02265229 0,05073055 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02265229 0,0506812 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02265229 0,05063195 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02265229 0,05058279 ! regulation of organ growth GO:0046620 11 10 0,000 0,02265229 0,05053373 ! response to dsRNA GO:0043331 18 10 0,000 0,02265229 0,05048476 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02265229 0,05043589 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02265229 0,05038711 ! embryonic axis specification GO:0000578 12 10 0,000 0,02265229 0,05033843 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02265229 0,05028984 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02265229 0,05024135 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02265229 0,05019294 ! cranial nerve development GO:0021545 12 10 0,000 0,02265229 0,05014464 ! fucose catabolic process GO:0019317 16 10 0,000 0,02265229 0,05009642 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02265229 0,0500483 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02265229 0,05000027 ! protein sumoylation GO:0016925 12 10 0,000 0,02265229 0,04995233 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02265229 0,04990448 ! zymogen activation GO:0031638 14 10 0,000 0,02265229 0,04985672 ! salivary gland development GO:0007431 22 10 0,000 0,02265229 0,04980906 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02265229 0,04976149 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02265229 0,049714 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02265229 0,04966661 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02265229 0,04961931 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02265229 0,0495721 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02265229 0,04952498 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02265229 0,04947795 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02265229 0,049431 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02265229 0,04938415 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02265229 0,04933738 GO:0043470|regulation of carbohydrate catabolic process, ! embryonic gut development GO:0048566 11 10 0,000 0,02265229 0,04929071 ! activation of innate immune response GO:0002218 10 10 0,000 0,02265229 0,04924412 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02265229 0,04919762 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02265229 0,0491512 ! developmental induction GO:0031128 13 10 0,000 0,02265229 0,04910488 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02265229 0,04905864 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02265229 0,04901249 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02265229 0,04896643 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02265229 0,04892045 ! rRNA transcription GO:0009303 17 11 0,000 0,02488981 0,05370222 ! respiratory burst GO:0045730 14 11 0,000 0,02488981 0,05365189 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02488981 0,05360165 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02488981 0,05355151 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02488981 0,05350146 ! virus-host interaction GO:0019048 17 11 0,000 0,02488981 0,05345151 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,02488981 0,05340165 ! filopodium assembly GO:0046847 19 11 0,000 0,02488981 0,05335188 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02488981 0,0533022 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02488981 0,05325262 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02488981 0,05320313 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02488981 0,05315373 ! mating GO:0007618 14 11 0,000 0,02488981 0,05310442 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02488981 0,05305521 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02488981 0,05300608 ! bone resorption GO:0045453 16 11 0,000 0,02488981 0,05295705 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02488981 0,0529081 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02488981 0,05285925 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02488981 0,05281049 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02488981 0,05276181 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02488981 0,05271323 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02488981 0,05266474 ! syncytium formation GO:0006949 15 11 0,000 0,02488981 0,05261633 ! plasma membrane organization GO:0007009 18 11 0,000 0,02488981 0,05256801 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02488981 0,05251979 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02488981 0,05247165 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02488981 0,0524236 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02488981 0,05237563 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02488981 0,05232776 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02488981 0,05227997 ! adult heart development GO:0007512 11 11 0,000 0,02488981 0,05223227 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02488981 0,05218466 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02488981 0,05213713 ! temperature homeostasis GO:0001659 16 11 0,000 0,02488981 0,05208969 ! L-glutamate transport GO:0015813 16 11 0,000 0,02488981 0,05204233 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02488981 0,05199507 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02488981 0,05194788 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02488981 0,05190079 ! stem cell development GO:0048864 29 11 0,000 0,02488981 0,05185377 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02488981 0,05180685 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02488981 0,05176001 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02488981 0,05171325 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02488981 0,05166658 ! vasoconstriction GO:0042310 15 11 0,000 0,02488981 0,05161999 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02488981 0,05157348 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02488981 0,05152706 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02488981 0,05148073 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02488981 0,05143447 ! ribosome assembly GO:0042255 13 11 0,000 0,02488981 0,0513883 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02488981 0,05134221 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02488981 0,05129621 ! chromatin silencing GO:0006342 19 11 0,000 0,02488981 0,05125028 ! nucleosome positioning GO:0016584 13 11 0,000 0,02488981 0,05120444 ! T cell homeostasis GO:0043029 20 11 0,000 0,02488981 0,05115868 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02488981 0,05111301 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02488981 0,05106741 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02488981 0,0510219 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02488981 0,05097646 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02488981 0,05093111 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02488981 0,05088584 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02488981 0,05084065 ! male genitalia development GO:0030539 13 11 0,000 0,02488981 0,05079553 ! cholesterol efflux GO:0033344 19 11 0,000 0,02488981 0,0507505 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02488981 0,05070555 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02488981 0,05066068 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02488981 0,05061589 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02488981 0,05057117 GO:0010829|negative regulation of glucose transport, ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02488981 0,05052654 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02488981 0,05048198 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02488981 0,0504375 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02488981 0,0503931 ! lysogeny GO:0030069 18 11 0,000 0,02488981 0,05034878 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02488981 0,05030454 ! acrosome reaction GO:0007340 13 11 0,000 0,02488981 0,05026037 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02488981 0,05021629 ! lactation GO:0007595 20 12 0,000 0,02712233 0,05467254 ! reproductive cellular process GO:0048610 14 12 0,000 0,02712233 0,05462467 ! tRNA modification GO:0006400 14 12 0,000 0,02712233 0,05457688 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02712233 0,05452917 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02712233 0,05448155 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02712233 0,054434 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02712233 0,05438655 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02712233 0,05433917 ! non-recombinational repair GO:0000726 19 12 0,000 0,02712233 0,05429188 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02712233 0,05424467 ! peroxisomal transport GO:0043574 21 12 0,000 0,02712233 0,05419754 ! cartilage condensation GO:0001502 18 12 0,000 0,02712233 0,05415049 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02712233 0,05410353 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02712233 0,05405665 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02712233 0,05400984 ! heart looping GO:0001947 15 12 0,000 0,02712233 0,05396312 ! palate development GO:0060021 15 12 0,000 0,02712233 0,05391648 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,02712233 0,05386992 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02712233 0,05382344 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02712233 0,05377704 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02712233 0,05373072 ! arginine metabolic process GO:0006525 13 12 0,000 0,02712233 0,05368448 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02712233 0,05363832 ! methionine metabolic process GO:0006555 13 12 0,000 0,02712233 0,05359224 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02712233 0,05354624 ! Golgi organization GO:0007030 18 12 0,000 0,02712233 0,05350032 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02712233 0,05345447 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02712233 0,05340871 ! monoamine transport GO:0015844 13 12 0,000 0,02712233 0,05336302 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02712233 0,05331741 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02712233 0,05327188 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02712233 0,05322642 ! L-amino acid transport GO:0015807 20 12 0,000 0,02712233 0,05318105 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02712233 0,05313575 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02712233 0,05309053 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02712233 0,05304538 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02712233 0,05300031 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02712233 0,05295532 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02712233 0,05291041 ! cerebellum development GO:0021549 13 12 0,000 0,02712233 0,05286557 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02712233 0,0528208 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02712233 0,05277612 ! histone acetylation GO:0016573 23 12 0,000 0,02712233 0,0527315 ! histone methylation GO:0016571 15 12 0,000 0,02712233 0,05268697 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02712233 0,05264251 ! gland morphogenesis GO:0022612 23 12 0,000 0,02712233 0,05259812 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02712233 0,05255381 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02712233 0,05250957 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02712233 0,05246541 ! response to gamma radiation GO:0010332 20 12 0,000 0,02712233 0,05242132 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02712233 0,0523773 ! intestinal absorption GO:0050892 19 12 0,000 0,02712233 0,05233336 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02712233 0,0522895 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02712233 0,0522457 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02712233 0,05220198 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02712233 0,05215834 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02712233 0,05211476 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02712233 0,05207126 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02712233 0,05202783 ! microspike assembly GO:0030035 23 12 0,000 0,02712233 0,05198447 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02712233 0,05194119 ! response to cold GO:0009409 14 12 0,000 0,02712233 0,05189798 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02934987 0,05611364 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02934987 0,05606703 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02934987 0,05602051 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02934987 0,05597405 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02934987 0,05592768 ! water transport GO:0006833 17 13 0,000 0,02934987 0,05588138 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02934987 0,05583516 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02934987 0,05578902 ! lipid localization GO:0010876 24 13 0,000 0,02934987 0,05574295 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02934987 0,05569695 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02934987 0,05565104 ! organelle fusion GO:0048284 28 13 0,000 0,02934987 0,0556052 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02934987 0,05555943 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02934987 0,05551374 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02934987 0,05546813 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02934987 0,05542259 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02934987 0,05537712 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02934987 0,05533173 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02934987 0,05528641 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02934987 0,05524117 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02934987 0,055196 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02934987 0,05515091 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02934987 0,05510589 ! NAD metabolic process GO:0019674 21 13 0,000 0,02934987 0,05506094 ! exocrine system development GO:0035272 27 13 0,000 0,02934987 0,05501606 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02934987 0,05497126 ! bone mineralization GO:0030282 15 13 0,000 0,02934987 0,05492653 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02934987 0,05488188 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02934987 0,05483729 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02934987 0,05479278 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02934987 0,05474835 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02934987 0,05470398 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02934987 0,05465968 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,02934987 0,05461546 ! genitalia development GO:0048806 15 13 0,000 0,02934987 0,05457131 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02934987 0,05452723 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,02934987 0,05448322 ! cellular pigmentation GO:0033059 24 13 0,000 0,02934987 0,05443928 ! tissue regeneration GO:0042246 21 13 0,000 0,02934987 0,05439541 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02934987 0,05435162 ! cofactor transport GO:0051181 19 13 0,000 0,02934987 0,05430789 ! NADP metabolic process GO:0006739 18 13 0,000 0,02934987 0,05426424 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02934987 0,05422065 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02934987 0,05417713 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02934987 0,05413369 ! gas transport GO:0015669 18 13 0,000 0,02934987 0,05409031 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02934987 0,05404701 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02934987 0,05400377 ! regulation of axon extension GO:0030516 23 13 0,000 0,02934987 0,0539606 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02934987 0,0539175 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02934987 0,05387447 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02934987 0,05383151 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02934987 0,05378861 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02934987 0,05374579 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02934987 0,05370303 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,03157244 0,05772386 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,03157244 0,05767801 ! superoxide anion generation GO:0042554 18 14 0,000 0,03157244 0,05763223 ! neuron maturation GO:0042551 21 14 0,000 0,03157244 0,05758653 ! regulation of S phase GO:0033261 18 14 0,000 0,03157244 0,0575409 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,03157244 0,05749534 ! myotube differentiation GO:0014902 21 14 0,000 0,03157244 0,05744985 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,03157244 0,05740444 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,03157244 0,05735909 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,03157244 0,05731382 ! inositol metabolic process GO:0006020 20 14 0,000 0,03157244 0,05726862 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,03157244 0,05722349 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,03157244 0,05717843 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,03157244 0,05713345 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,03157244 0,05708853 ! gene silencing by RNA GO:0031047 20 14 0,000 0,03157244 0,05704369 ! response to cAMP GO:0051591 19 14 0,000 0,03157244 0,05699891 ! limbic system development GO:0021761 25 14 0,000 0,03157244 0,0569542 ! startle response GO:0001964 21 14 0,000 0,03157244 0,05690957 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,03157244 0,056865 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,03157244 0,05682051 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,03157244 0,05677608 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,03157244 0,05673173 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,03157244 0,05668744 ! glycine metabolic process GO:0006544 22 14 0,000 0,03157244 0,05664322 ! pituitary gland development GO:0021983 23 14 0,000 0,03157244 0,05659907 ! cellular response to starvation GO:0009267 21 14 0,000 0,03157244 0,05655499 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,03157244 0,05651098 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,03157244 0,05646704 ! regulation of heart rate GO:0002027 23 14 0,000 0,03157244 0,05642316 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,03157244 0,05637936 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,03157244 0,05633562 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,03157244 0,05629195 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,03157244 0,05624834 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,03157244 0,05620481 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,03157244 0,05616134 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,03157244 0,05611794 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,03157244 0,0560746 ! axon cargo transport GO:0008088 27 14 0,000 0,03157244 0,05603134 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,03157244 0,05598814 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,03157244 0,055945 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,03157244 0,05590193 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03157244 0,05585893 ! mRNA splice site selection GO:0006376 26 14 0,000 0,03157244 0,055816 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,03157244 0,05577313 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,03157244 0,05573032 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,03157244 0,05568759 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,03157244 0,05564491 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,03157244 0,05560231 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,03157244 0,05555976 ! muscle maintenance GO:0046716 19 14 0,000 0,03157244 0,05551729 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,03157244 0,05547487 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,03157244 0,05543253 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,03157244 0,05539024 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,03157244 0,05534803 ! cell killing GO:0001906 20 14 0,000 0,03157244 0,05530587 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,03157244 0,05526378 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,03157244 0,05522176 ! cilium assembly GO:0042384 20 14 0,000 0,03157244 0,0551798 ! peptide hormone secretion GO:0030072 23 14 0,000 0,03157244 0,0551379 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03379004 0,05896593 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03379004 0,05892123 ! metencephalon development GO:0022037 19 15 0,000 0,03379004 0,05887659 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03379004 0,05883202 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03379004 0,05878752 ! skin development GO:0043588 25 15 0,000 0,03379004 0,05874308 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03379004 0,05869872 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03379004 0,05865441 ! lipid phosphorylation GO:0046834 23 15 0,000 0,03379004 0,05861018 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03379004 0,05856601 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03379004 0,05852191 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03379004 0,05847788 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03379004 0,05843391 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03379004 0,05839001 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03379004 0,05834617 ! adult walking behavior GO:0007628 25 15 0,000 0,03379004 0,0583024 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03379004 0,0582587 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03379004 0,05821506 ! myoblast differentiation GO:0045445 27 15 0,000 0,03379004 0,05817148 ! centrosome cycle GO:0007098 16 15 0,000 0,03379004 0,05812797 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03379004 0,05808453 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03379004 0,05804115 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03379004 0,05799784 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03379004 0,05795459 ! cerebral cortex development GO:0021987 29 15 0,000 0,03379004 0,0579114 ! response to osmotic stress GO:0006970 22 15 0,000 0,03379004 0,05786828 ! vesicle coating GO:0006901 25 15 0,000 0,03379004 0,05782522 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03379004 0,05778223 ! DNA integration GO:0015074 22 15 0,000 0,03379004 0,0577393 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,03379004 0,05769644 ! peptide secretion GO:0002790 27 15 0,000 0,03379004 0,05765363 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03379004 0,0576109 ! regulation of vasodilation GO:0042312 24 15 0,000 0,03379004 0,05756822 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,03379004 0,05752561 ! neuron recognition GO:0008038 22 15 0,000 0,03379004 0,05748306 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03379004 0,05744058 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03379004 0,05739815 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,03379004 0,05735579 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03379004 0,0573135 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03379004 0,05727126 ! biomineral formation GO:0031214 18 15 0,000 0,03379004 0,05722909 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03379004 0,05718698 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03379004 0,05714493 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03379004 0,05710294 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03379004 0,05706101 ! organic cation transport GO:0015695 19 15 0,000 0,03379004 0,05701915 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03379004 0,05697735 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03379004 0,0569356 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03379004 0,05689392 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03379004 0,0568523 ! defense response to virus GO:0051607 27 15 0,000 0,03379004 0,05681075 ! peptide hormone processing GO:0016486 19 15 0,000 0,03379004 0,05676925 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03379004 0,05672781 ! protein secretion GO:0009306 27 16 0,000 0,0360027 0,0603984 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,0360027 0,06035437 ! hormone secretion GO:0046879 25 16 0,000 0,0360027 0,06031042 ! bone remodeling GO:0046849 24 16 0,000 0,0360027 0,06026652 ! endothelial cell migration GO:0043542 22 16 0,000 0,0360027 0,06022269 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,0360027 0,06017892 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,0360027 0,06013522 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0360027 0,06009158 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,0360027 0,06004801 ! glial cell development GO:0021782 24 16 0,000 0,0360027 0,06000449 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,0360027 0,05996104 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,0360027 0,05991766 ! protein polyubiquitination GO:0000209 26 16 0,000 0,0360027 0,05987433 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,0360027 0,05983107 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,0360027 0,05978787 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,0360027 0,05974473 ! fructose metabolic process GO:0006000 20 16 0,000 0,0360027 0,05970166 ! regulation of protein binding GO:0043393 27 16 0,000 0,0360027 0,05965865 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,0360027 0,05961569 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,0360027 0,05957281 ! protein export from nucleus GO:0006611 24 16 0,000 0,0360027 0,05952998 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,0360027 0,05948721 ! DNA replication initiation GO:0006270 25 16 0,000 0,0360027 0,05944451 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,0360027 0,05940187 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,0360027 0,05935928 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,0360027 0,05931676 ! diencephalon development GO:0021536 25 16 0,000 0,0360027 0,0592743 ! oogenesis GO:0048477 23 16 0,000 0,0360027 0,0592319 ! neural crest cell migration GO:0001755 24 16 0,000 0,0360027 0,05918956 ! G1 phase GO:0051318 27 16 0,000 0,0360027 0,05914729 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,0360027 0,05910507 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0360027 0,05906291 GO:0006626|protein targeting to mitochondrion, ! steroid catabolic process GO:0006706 22 16 0,000 0,0360027 0,05902081 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,0360027 0,05897878 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,0360027 0,0589368 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,0360027 0,05889488 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,0360027 0,05885302 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,0360027 0,05881122 ! sperm-egg recognition GO:0035036 16 16 0,000 0,0360027 0,05876948 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,0360027 0,0587278 ! nerve development GO:0021675 18 16 0,000 0,0360027 0,05868618 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,0360027 0,05864462 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,0360027 0,05860311 ! negative regulation of translation GO:0017148 22 16 0,000 0,0360027 0,05856167 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03821041 0,06210879 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03821041 0,06206493 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03821041 0,06202113 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03821041 0,06197739 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03821041 0,06193371 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03821041 0,0618901 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03821041 0,06184654 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03821041 0,06180305 ! signal complex assembly GO:0007172 29 17 0,000 0,03821041 0,06175962 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03821041 0,06171625 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03821041 0,06167294 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,03821041 0,06162969 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03821041 0,0615865 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03821041 0,06154337 ! memory GO:0007613 25 17 0,000 0,03821041 0,06150031 ! keratinization GO:0031424 17 17 0,000 0,03821041 0,0614573 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03821041 0,06141435 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03821041 0,06137146 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03821041 0,06132864 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03821041 0,06128587 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,03821041 0,06124316 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03821041 0,06120051 ! vacuolar transport GO:0007034 24 17 0,000 0,03821041 0,06115792 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,03821041 0,06111539 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03821041 0,06107292 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03821041 0,06103051 ! membrane budding GO:0006900 29 17 0,000 0,03821041 0,06098816 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03821041 0,06094586 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03821041 0,06090363 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03821041 0,06086145 ! body fluid secretion GO:0007589 27 17 0,000 0,03821041 0,06081933 ! stem cell differentiation GO:0048863 36 17 0,000 0,03821041 0,06077727 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03821041 0,06073527 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03821041 0,06069333 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03821041 0,06065144 ! sensory perception of pain GO:0019233 23 17 0,000 0,03821041 0,06060961 ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03821041 0,06056784 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03821041 0,06052613 ! synaptogenesis GO:0007416 24 17 0,000 0,03821041 0,06048447 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03821041 0,06044287 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03821041 0,06040133 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03821041 0,06035985 ! cell-cell junction organization GO:0045216 25 17 0,000 0,03821041 0,06031842 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03821041 0,06027705 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03821041 0,06023573 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03821041 0,06019448 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03821041 0,06015328 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03821041 0,06011213 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,04041319 0,06353406 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,04041319 0,06349067 ! positive regulation of translation GO:0045727 28 18 0,000 0,04041319 0,06344733 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,04041319 0,06340405 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,04041319 0,06336083 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,04041319 0,06331767 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,04041319 0,06327456 ! cAMP metabolic process GO:0046058 33 18 0,000 0,04041319 0,06323152 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,04041319 0,06318854 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,04041319 0,06314561 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,04041319 0,06310274 ! axis specification GO:0009798 26 18 0,000 0,04041319 0,06305993 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,04041319 0,06301718 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,04041319 0,06297448 ! pancreas development GO:0031016 26 18 0,000 0,04041319 0,06293185 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,04041319 0,06288927 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,04041319 0,06284674 ! glutamine metabolic process GO:0006541 23 18 0,000 0,04041319 0,06280428 ! response to retinoic acid GO:0032526 25 18 0,000 0,04041319 0,06276187 ! pigmentation during development GO:0048066 31 18 0,000 0,04041319 0,06271952 ! central nervous system neuron development GO:0021954 30 18 0,000 0,04041319 0,06267723 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,04041319 0,062635 ! fucose metabolic process GO:0006004 26 18 0,000 0,04041319 0,06259282 ! response to fungus GO:0009620 19 18 0,000 0,04041319 0,0625507 ! peptide cross-linking GO:0018149 31 18 0,000 0,04041319 0,06250863 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,04041319 0,06246662 ! heart process GO:0003015 27 18 0,000 0,04041319 0,06242467 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,04041319 0,06238278 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,04041319 0,06234094 ! visual learning GO:0008542 35 18 0,000 0,04041319 0,06229915 ! somitogenesis GO:0001756 24 18 0,000 0,04041319 0,06225742 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,04041319 0,06221575 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,04041319 0,06217414 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,04041319 0,06213258 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,04041319 0,06209107 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,04041319 0,06204962 ! vitamin transport GO:0051180 24 18 0,000 0,04041319 0,06200823 ! hormone transport GO:0009914 27 18 0,000 0,04041319 0,06196689 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,04041319 0,06192561 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,04041319 0,06188438 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,04041319 0,0618432 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,04041319 0,06180208 ! cell-cell recognition GO:0009988 20 18 0,000 0,04041319 0,06176102 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,04041319 0,06172001 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,04041319 0,06167905 ! regulation of glucose import GO:0046324 21 18 0,000 0,04041319 0,06163815 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,04041319 0,06159731 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,04041319 0,06155651 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,04041319 0,06151577 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,04041319 0,06147509 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,04261105 0,06477556 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,04261105 0,06473277 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,04261105 0,06469005 ! positive regulation of ossification GO:0045778 30 19 0,000 0,04261105 0,06464737 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,04261105 0,06460476 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,04261105 0,0645622 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,04261105 0,0645197 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,04261105 0,06447725 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,04261105 0,06443486 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,04261105 0,06439252 ! regeneration GO:0031099 32 19 0,000 0,04261105 0,06435024 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,04261105 0,06430802 ! response to alkaloid GO:0043279 32 19 0,000 0,04261105 0,06426585 ! sensory perception of taste GO:0050909 23 19 0,000 0,04261105 0,06422373 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,04261105 0,06418168 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,04261105 0,06413967 ! smooth muscle contraction GO:0006939 36 19 0,000 0,04261105 0,06409772 ! peroxisome organization GO:0007031 29 19 0,000 0,04261105 0,06405583 ! digestive system process GO:0022600 30 19 0,000 0,04261105 0,06401399 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,04261105 0,06397221 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,04261105 0,06393048 ! response to vitamin A GO:0033189 26 19 0,000 0,04261105 0,0638888 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,04261105 0,06384718 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,04261105 0,06380561 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,04261105 0,0637641 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,04261105 0,06372264 ! response to starvation GO:0042594 30 19 0,000 0,04261105 0,06368123 ! sex determination GO:0007530 29 19 0,000 0,04261105 0,06363988 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,04261105 0,06359858 ! plasma membrane fusion GO:0045026 23 19 0,000 0,04261105 0,06355734 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,04261105 0,06351615 ! cytolysis GO:0019835 20 19 0,000 0,04261105 0,06347501 ! renal system process GO:0003014 35 19 0,000 0,04261105 0,06343393 ! vasodilation GO:0042311 33 19 0,000 0,04261105 0,0633929 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,04261105 0,06335192 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,04261105 0,06331099 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,04261105 0,06327012 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,04261105 0,0632293 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,04261105 0,06318854 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,04261105 0,06314782 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,04261105 0,06310716 ! sarcomere organization GO:0045214 23 19 0,000 0,04261105 0,06306655 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,04261105 0,06302599 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,04261105 0,06298549 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,04261105 0,06294503 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,04261105 0,06290463 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,04261105 0,06286428 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,04261105 0,06282399 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,04261105 0,06278374 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,04261105 0,06274355 ! protein stabilization GO:0050821 26 19 0,000 0,04261105 0,0627034 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,04480401 0,06588824 ! iron ion transport GO:0006826 37 20 0,000 0,04480401 0,06584614 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,04480401 0,0658041 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,04480401 0,0657621 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,04480401 0,06572016 ! response to vitamin GO:0033273 29 20 0,000 0,04480401 0,06567828 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,04480401 0,06563644 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,04480401 0,06559466 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,04480401 0,06555293 ! spinal cord development GO:0021510 31 20 0,000 0,04480401 0,06551126 ! response to ethanol GO:0045471 37 20 0,000 0,04480401 0,06546964 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,04480401 0,06542807 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,04480401 0,06538656 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,04480401 0,06534509 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,04480401 0,06530368 ! chromosome condensation GO:0030261 31 20 0,000 0,04480401 0,06526233 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,04480401 0,06522102 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,04480401 0,06517977 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,04480401 0,06513857 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,04480401 0,06509742 ! pallium development GO:0021543 38 20 0,000 0,04480401 0,06505632 ! DNA modification GO:0006304 28 20 0,000 0,04480401 0,06501528 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,04480401 0,06497428 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,04480401 0,06493334 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,04480401 0,06489245 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,04480401 0,06485161 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,04480401 0,06481083 ! collagen catabolic process GO:0030574 25 20 0,000 0,04480401 0,06477009 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,04480401 0,06472941 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,04480401 0,06468877 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,04480401 0,06464819 ! alditol metabolic process GO:0019400 24 20 0,000 0,04480401 0,06460766 ! actin filament-based movement GO:0030048 34 20 0,000 0,04480401 0,06456718 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04699206 0,06767799 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04699206 0,06763563 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04699206 0,06759334 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04699206 0,06755109 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,04699206 0,0675089 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04699206 0,06746676 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04699206 0,06742467 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04699206 0,06738263 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04699206 0,06734065 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04699206 0,06729872 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04699206 0,06725684 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04699206 0,06721501 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04699206 0,06717324 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04699206 0,06713152 ! vesicle docking GO:0048278 27 21 0,000 0,04699206 0,06708985 ! phototransduction GO:0007602 25 21 0,000 0,04699206 0,06704823 ! dendrite development GO:0016358 35 21 0,000 0,04699206 0,06700666 ! visual behavior GO:0007632 39 21 0,000 0,04699206 0,06696514 ! ovarian follicle development GO:0001541 30 21 0,000 0,04699206 0,06692368 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04699206 0,06688227 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04699206 0,0668409 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04699206 0,06679959 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04699206 0,06675833 ! cell aging GO:0007569 32 21 0,000 0,04699206 0,06671713 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04699206 0,06667597 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,04699206 0,06663486 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04699206 0,0665938 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04699206 0,0665528 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04699206 0,06651184 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04699206 0,06647094 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04699206 0,06643008 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,04699206 0,06638928 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04699206 0,06634852 ! fatty acid transport GO:0015908 30 21 0,000 0,04699206 0,06630782 ! immunoglobulin production GO:0002377 33 21 0,000 0,04699206 0,06626716 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,04699206 0,06622656 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04699206 0,066186 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04699206 0,0661455 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,04699206 0,06610504 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04699206 0,06606464 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04699206 0,06602428 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04699206 0,06598397 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04699206 0,06594371 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04699206 0,0659035 ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04699206 0,06586334 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04699206 0,06582323 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04699206 0,06578317 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04699206 0,06574315 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04917523 0,06875564 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,04917523 0,06871387 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04917523 0,06867215 ! viral genome replication GO:0019079 29 22 0,000 0,04917523 0,06863048 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04917523 0,06858886 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04917523 0,06854729 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04917523 0,06850577 ! molting cycle process GO:0022404 40 22 0,000 0,04917523 0,06846431 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04917523 0,06842289 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04917523 0,06838152 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04917523 0,0683402 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04917523 0,06829893 ! vasculogenesis GO:0001570 33 22 0,000 0,04917523 0,06825771 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04917523 0,06821655 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,04917523 0,06817543 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04917523 0,06813436 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04917523 0,06809334 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,04917523 0,06805237 ! lysosome organization GO:0007040 37 22 0,000 0,04917523 0,06801144 ! ureteric bud development GO:0001657 32 22 0,000 0,04917523 0,06797057 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04917523 0,06792975 ! regulation of behavior GO:0050795 38 22 0,000 0,04917523 0,06788897 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04917523 0,06784825 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04917523 0,06780757 ! membrane depolarization GO:0051899 35 22 0,000 0,04917523 0,06776695 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04917523 0,06772637 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04917523 0,06768584 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,04917523 0,06764535 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04917523 0,06760492 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04917523 0,06756454 ! blastocyst development GO:0001824 37 22 0,000 0,04917523 0,0675242 ! neural tube closure GO:0001843 33 22 0,000 0,04917523 0,06748391 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04917523 0,06744367 ! protein tetramerization GO:0051262 39 22 0,000 0,04917523 0,06740348 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,05135352 0,07034729 ! neuron fate commitment GO:0048663 32 23 0,000 0,05135352 0,07030542 ! embryonic pattern specification GO:0009880 31 23 0,000 0,05135352 0,0702636 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,05135352 0,07022182 ! myelination GO:0042552 35 23 0,000 0,05135352 0,0701801 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,05135352 0,07013842 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,05135352 0,0700968 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,05135352 0,07005522 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,05135352 0,0700137 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,05135352 0,06997222 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,05135352 0,06993079 ! vesicle targeting GO:0006903 32 23 0,000 0,05135352 0,06988941 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,05135352 0,06984808 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,05135352 0,0698068 ! osteoblast differentiation GO:0001649 40 23 0,000 0,05135352 0,06976557 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,05135352 0,06972438 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,05135352 0,06968325 ! interaction with host GO:0051701 37 23 0,000 0,05135352 0,06964216 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,05135352 0,06960112 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,05135352 0,06956013 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,05135352 0,06951919 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,05135352 0,0694783 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,05135352 0,06943745 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,05135352 0,06939665 ! cell fate determination GO:0001709 45 23 0,000 0,05135352 0,0693559 ! pentose metabolic process GO:0019321 31 23 0,000 0,05135352 0,0693152 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,05135352 0,06927455 ! spermatid development GO:0007286 33 23 0,000 0,05135352 0,06923394 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,05135352 0,06919338 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,05135352 0,06915287 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,05135352 0,06911241 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,05135352 0,06907199 ! telomere organization GO:0032200 32 23 0,000 0,05135352 0,06903162 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,05135352 0,0689913 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,05135352 0,06895102 ! regulation of amine transport GO:0051952 38 23 0,000 0,05135352 0,0689108 ! liver development GO:0001889 40 23 0,000 0,05135352 0,06887062 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,05352695 0,07174358 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,05352695 0,0717018 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,05352695 0,07166006 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,05352695 0,07161838 ! superoxide metabolic process GO:0006801 32 24 0,000 0,05352695 0,07157674 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,05352695 0,07153515 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,05352695 0,0714936 ! fat cell differentiation GO:0045444 37 24 0,000 0,05352695 0,07145211 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,05352695 0,07141067 ! sperm motility GO:0030317 27 24 0,000 0,05352695 0,07136927 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,05352695 0,07132792 ! vacuole organization GO:0007033 39 24 0,000 0,05352695 0,07128662 ! receptor metabolic process GO:0043112 37 24 0,000 0,05352695 0,07124536 ! neural crest cell development GO:0014032 39 24 0,000 0,05352695 0,07120416 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,05352695 0,071163 ! primary neural tube formation GO:0014020 35 24 0,000 0,05352695 0,07112189 ! negative regulation of cell development GO:0010721 56 24 0,000 0,05352695 0,07108082 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,05352695 0,07103981 ! base-excision repair GO:0006284 31 24 0,000 0,05352695 0,07099884 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,05352695 0,07095792 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,05352695 0,07091704 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,05352695 0,07087622 ! glutathione metabolic process GO:0006749 29 24 0,000 0,05352695 0,07083544 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,05352695 0,0707947 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,05352695 0,07075402 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,05352695 0,07071338 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,05569552 0,07353599 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,05569552 0,0734938 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,05569552 0,07345166 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,05569552 0,07340957 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,05569552 0,07336753 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,05569552 0,07332553 ! peptide transport GO:0015833 43 25 0,000 0,05569552 0,07328358 ! male gonad development GO:0008584 33 25 0,000 0,05569552 0,07324168 ! iron ion homeostasis GO:0055072 39 25 0,000 0,05569552 0,07319983 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,05569552 0,07315803 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,05569552 0,07311627 ! phospholipid transport GO:0015914 35 25 0,000 0,05569552 0,07307456 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,05569552 0,0730329 ! detection of light stimulus GO:0009583 30 25 0,000 0,05569552 0,07299128 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,05569552 0,07294972 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,05569552 0,0729082 ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,05569552 0,07286672 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,05785925 0,0756545 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,05785925 0,07561152 ! translational initiation GO:0006413 43 26 0,000 0,05785925 0,07556858 ! regulation of pH GO:0006885 36 26 0,000 0,05785925 0,07552569 ! circadian rhythm GO:0007623 42 26 0,000 0,05785925 0,07548286 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,05785925 0,07544006 ! post-embryonic development GO:0009791 42 26 0,000 0,05785925 0,07539732 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,05785925 0,07535463 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,05785925 0,07531198 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,05785925 0,07526939 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,05785925 0,07522684 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,05785925 0,07518434 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,05785925 0,07514188 ! regulation of coagulation GO:0050818 39 26 0,000 0,05785925 0,07509948 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,06001814 0,07785771 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,06001814 0,07781383 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,06001814 0,07776999 ! membrane docking GO:0022406 39 27 0,000 0,06001814 0,0777262 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,06001814 0,07768246 ! catechol metabolic process GO:0009712 43 27 0,000 0,06001814 0,07763877 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,06001814 0,07759512 ! acute-phase response GO:0006953 42 27 0,000 0,06001814 0,07755153 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,06001814 0,07750799 ! myofibril assembly GO:0030239 36 27 0,000 0,06001814 0,07746449 GO:0055002|striated muscle cell development, ! response to ionizing radiation GO:0010212 47 27 0,000 0,06001814 0,07742105 ! natural killer cell activation GO:0030101 35 27 0,000 0,06001814 0,07737765 ! lipid oxidation GO:0034440 38 27 0,000 0,06001814 0,0773343 GO:0019395|fatty acid oxidation, ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,06001814 0,077291 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,06001814 0,07724775 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,06001814 0,07720455 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,06001814 0,07716139 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,06001814 0,07711828 ! gene silencing GO:0016458 41 27 0,000 0,06001814 0,07707522 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,06217221 0,07979692 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,06217221 0,07975242 ! phenol metabolic process GO:0018958 44 28 0,000 0,06217221 0,07970796 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,06217221 0,07966356 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,06217221 0,0796192 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,06217221 0,07957489 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,06217221 0,07953064 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,06217221 0,07948643 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,06217221 0,07944227 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,06217221 0,07939816 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,06217221 0,0793541 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,06217221 0,07931009 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,06217221 0,07926612 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,06217221 0,07922221 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,06217221 0,07917834 ! mesoderm formation GO:0001707 46 28 0,000 0,06217221 0,07913452 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,06217221 0,07909076 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,06217221 0,07904703 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,06217221 0,07900336 ! ensheathment of neurons GO:0007272 43 28 0,000 0,06217221 0,07895974 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,06217221 0,07891616 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,06217221 0,07887263 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,06217221 0,07882915 ! neural tube formation GO:0001841 41 28 0,000 0,06217221 0,07878572 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,06217221 0,07874234 ! placenta development GO:0001890 37 28 0,000 0,06217221 0,078699 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,06432147 0,08137479 ! regulation of innate immune response GO:0045088 38 29 0,000 0,06432147 0,08133006 ! ovulation cycle process GO:0022602 41 29 0,000 0,06432147 0,08128537 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,06432147 0,08124073 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,06432147 0,08119614 ! mismatch repair GO:0006298 34 29 0,000 0,06432147 0,0811516 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,06432147 0,08110711 ! muscle cell development GO:0055001 38 29 0,000 0,06432147 0,08106267 ! formation of primary germ layer GO:0001704 48 29 0,000 0,06432147 0,08101828 ! telencephalon development GO:0021537 52 29 0,000 0,06432147 0,08097393 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,06432147 0,08092964 ! eye morphogenesis GO:0048592 51 29 0,000 0,06432147 0,08088539 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,06432147 0,08084119 ! tissue homeostasis GO:0001894 42 29 0,000 0,06432147 0,08079704 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,06646592 0,08344521 ! collagen metabolic process GO:0032963 40 30 0,000 0,06646592 0,08339968 ! organic anion transport GO:0015711 51 30 0,000 0,06646592 0,08335421 ! cholesterol transport GO:0030301 46 30 0,000 0,06646592 0,08330878 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,06646592 0,08326341 ! spliceosome assembly GO:0000245 49 30 0,000 0,06646592 0,08321808 ! spindle organization GO:0007051 37 30 0,000 0,06646592 0,08317281 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,06646592 0,08312758 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,06646592 0,0830824 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,06646592 0,08303727 ! ovulation cycle GO:0042698 43 30 0,000 0,06646592 0,08299219 ! hindbrain development GO:0030902 45 30 0,000 0,06646592 0,08294716 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,06646592 0,08290218 ! adult locomotory behavior GO:0008344 47 30 0,000 0,06646592 0,08285724 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,06646592 0,08281236 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,06646592 0,08276752 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,06646592 0,08272274 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,06646592 0,082678 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,06646592 0,08263331 ! glial cell differentiation GO:0010001 55 31 0,000 0,06860558 0,08524735 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,06860558 0,08520132 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,06860558 0,08515534 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,06860558 0,0851094 ! odontogenesis GO:0042476 50 31 0,000 0,06860558 0,08506352 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,06860558 0,08501769 ! segmentation GO:0035282 41 31 0,000 0,06860558 0,08497191 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,06860558 0,08492618 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,06860558 0,08488049 ! metanephros development GO:0001656 58 31 0,000 0,06860558 0,08483486 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,06860558 0,08478927 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,06860558 0,08474374 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,06860558 0,08469825 ! cell fate specification GO:0001708 37 31 0,000 0,06860558 0,08465281 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,06860558 0,08460742 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,06860558 0,08456208 ! RNA modification GO:0009451 40 31 0,000 0,06860558 0,08451678 ! regulation of muscle development GO:0048634 48 32 0,000 0,07074046 0,08710014 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,07074046 0,08705354 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,07074046 0,08700698 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,07074046 0,08696048 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,07074046 0,08691403 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,07074046 0,08686762 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,07074046 0,08682127 ! peripheral nervous system development GO:0007422 53 32 0,000 0,07074046 0,08677496 ! regulation of protein stability GO:0031647 48 32 0,000 0,07074046 0,08672871 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,07074046 0,0866825 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,07074046 0,08663635 ! cytokine production GO:0001816 44 32 0,000 0,07074046 0,08659024 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,07074046 0,08654418 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,07074046 0,08649817 ! vesicle localization GO:0051648 47 32 0,000 0,07074046 0,08645221 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,07287057 0,08900813 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,07287057 0,08896088 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,07287057 0,08891369 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,07287057 0,08886655 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,07287057 0,08881945 ! sister chromatid segregation GO:0000819 46 33 0,000 0,07287057 0,08877241 ! ear morphogenesis GO:0042471 42 33 0,000 0,07287057 0,08872541 ! actomyosin structure organization GO:0031032 43 33 0,000 0,07287057 0,08867847 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,07287057 0,08863157 ! nucleus organization GO:0006997 49 33 0,000 0,07287057 0,08858473 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,07287057 0,08853793 ! female gonad development GO:0008585 49 33 0,000 0,07287057 0,08849119 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,07287057 0,08844449 ! positive regulation of cell development GO:0010720 54 33 0,000 0,07287057 0,08839784 ! lipid homeostasis GO:0055088 55 33 0,000 0,07287057 0,08835124 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,07287057 0,08830469 ! regulation of proteolysis GO:0030162 50 33 0,000 0,07287057 0,08825819 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,07287057 0,08821174 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,07287057 0,08816534 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,07287057 0,08811898 ! cytokinesis GO:0000910 52 33 0,000 0,07287057 0,08807268 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,07287057 0,08802642 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,07499591 0,09054625 ! mRNA catabolic process GO:0006402 48 34 0,000 0,07499591 0,09049874 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,07499591 0,09045129 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,07499591 0,09040388 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,07499591 0,09035652 ! feeding behavior GO:0007631 45 34 0,000 0,07499591 0,09030922 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,07499591 0,09026196 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,07499591 0,09021475 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,07499591 0,09016759 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,07499591 0,09012048 ! female gamete generation GO:0007292 43 34 0,000 0,07499591 0,09007342 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,07499591 0,09002641 ! polyol metabolic process GO:0019751 44 34 0,000 0,07499591 0,08997945 ! aerobic respiration GO:0009060 47 34 0,000 0,07499591 0,08993254 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,07499591 0,08988567 ! embryonic organ development GO:0048568 45 34 0,000 0,07499591 0,08983886 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,07499591 0,08979209 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,07711651 0,09228303 ! Notch signaling pathway GO:0007219 56 35 0,000 0,07711651 0,09223504 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,07711651 0,0921871 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,07711651 0,09213921 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,07711651 0,09209137 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,07711651 0,09204358 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,07711651 0,09199584 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,07711651 0,09194815 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,07711651 0,09190051 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,07711651 0,09185291 ! glycogen metabolic process GO:0005977 48 35 0,000 0,07711651 0,09180537 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,07711651 0,09175788 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,07923237 0,0942267 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,07923237 0,09417801 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,07923237 0,09412936 ! negative regulation of binding GO:0051100 58 36 0,000 0,07923237 0,09408077 ! tissue remodeling GO:0048771 62 36 0,000 0,07923237 0,09403222 ! neural tube development GO:0021915 50 36 0,000 0,07923237 0,09398373 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,07923237 0,09393528 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,07923237 0,09388689 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,07923237 0,09383854 ! glucan metabolic process GO:0044042 49 36 0,000 0,07923237 0,09379024 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,08134349 0,09623973 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,08134349 0,09619025 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,08134349 0,09614082 ! learning GO:0007612 67 37 0,000 0,08134349 0,09609144 ! ion transmembrane transport GO:0034220 56 37 0,000 0,08134349 0,09604211 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,08134349 0,09599283 ! regulation of protein secretion GO:0050708 51 37 0,000 0,08134349 0,09594361 ! amino acid activation GO:0043038 52 37 0,000 0,08134349 0,09589443 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,08134349 0,0958453 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,0834499 0,09827689 ! gliogenesis GO:0042063 71 38 0,000 0,0834499 0,0982266 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,0834499 0,09817635 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,0834499 0,09812616 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,0834499 0,09807602 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,0834499 0,09802593 ! phagocytosis GO:0006909 60 38 0,000 0,0834499 0,09797589 ! mesenchymal cell development GO:0014031 64 38 0,000 0,0834499 0,0979259 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,0834499 0,09787597 ! maintenance of location in cell GO:0051651 69 38 0,000 0,0834499 0,09782608 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,0855516 0,10023875 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,0855516 0,10018772 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,0855516 0,10013673 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,0855516 0,10008579 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,0855516 0,10003491 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,0855516 0,09998408 ! male sex differentiation GO:0046661 53 39 0,000 0,0855516 0,0999333 ! chromatin remodeling GO:0006338 68 39 0,000 0,0855516 0,09988257 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,0855516 0,0998319 ! JNK cascade GO:0007254 54 39 0,000 0,0855516 0,09978127 ! developmental growth GO:0048589 62 39 0,000 0,0855516 0,0997307 ! cell growth GO:0016049 61 39 0,000 0,0855516 0,09968018 ! synapse organization GO:0050808 55 39 0,000 0,0855516 0,09962971 ! response to calcium ion GO:0051592 58 40 0,000 0,08764859 0,10202013 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,08764859 0,10196852 ! regulation of tube size GO:0035150 60 40 0,000 0,08764859 0,10191697 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,08764859 0,10186547 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,08764859 0,10181402 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,08764859 0,10176263 ! peptide metabolic process GO:0006518 56 40 0,000 0,08764859 0,10171129 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,08764859 0,10165999 ! inner ear development GO:0048839 57 40 0,000 0,08764859 0,10160875 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,08764859 0,10155757 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,08764859 0,10150643 ! B cell differentiation GO:0030183 62 40 0,000 0,08764859 0,10145534 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,08764859 0,10140431 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,08764859 0,10135333 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,08764859 0,1013024 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,08764859 0,10125152 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,0897409 0,10361651 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,0897409 0,10356452 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,0897409 0,10351258 ! glucose transport GO:0015758 52 41 0,000 0,0897409 0,10346069 ! endosome transport GO:0016197 71 41 0,000 0,0897409 0,10340886 ! striated muscle contraction GO:0006941 62 41 0,000 0,0897409 0,10335708 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,0897409 0,10330534 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,0897409 0,10325367 ! biopolymer methylation GO:0043414 62 41 0,000 0,0897409 0,10320204 ! mitochondrial transport GO:0006839 60 42 0,000 0,09182853 0,10555004 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,09182853 0,10549732 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,09182853 0,10544465 ! cellular component disassembly GO:0022411 64 42 0,000 0,09182853 0,10539203 ! hexose transport GO:0008645 54 42 0,000 0,09182853 0,10533947 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,09182853 0,10528695 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,09182853 0,10523449 ! excretion GO:0007588 63 42 0,000 0,09182853 0,10518209 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,09182853 0,10512973 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,09182853 0,10507743 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,09182853 0,10502518 ! positive regulation of binding GO:0051099 59 43 0,000 0,0939115 0,1073541 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,0939115 0,10730077 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,0939115 0,10724749 ! leukocyte migration GO:0050900 60 43 0,000 0,0939115 0,10719426 ! neuromuscular process GO:0050905 79 43 0,000 0,0939115 0,10714109 ! activation of caspase activity GO:0006919 65 43 0,000 0,0939115 0,10708797 ! tRNA processing GO:0008033 49 43 0,000 0,0939115 0,10703491 ! vesicle organization GO:0016050 79 43 0,000 0,0939115 0,10698189 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,0939115 0,10692893 ! methylation GO:0032259 64 43 0,000 0,0939115 0,10687602 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,0959898 0,10918721 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,0959898 0,10913324 ! glycolysis GO:0006096 53 44 0,000 0,0959898 0,10907932 ! regulation of action potential GO:0001508 71 44 0,000 0,0959898 0,10902545 ! regulation of ion transport GO:0043269 57 44 0,000 0,0959898 0,10897164 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,0959898 0,10891788 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,0959898 0,10886417 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,0959898 0,10881052 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,0959898 0,10875692 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,0959898 0,10870337 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,0959898 0,10864987 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,0959898 0,10859643 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,0959898 0,10854304 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,09806346 0,11083339 ! RNA catabolic process GO:0006401 64 45 0,000 0,09806346 0,11077895 ! positive regulation of defense response GO:0031349 59 45 0,000 0,09806346 0,11072457 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,09806346 0,11067024 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,09806346 0,11061596 ! cell recognition GO:0008037 58 45 0,000 0,09806346 0,11056174 ! cell maturation GO:0048469 60 45 0,000 0,09806346 0,11050757 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,09806346 0,11045345 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,10013247 0,11272868 ! cell redox homeostasis GO:0045454 63 46 0,000 0,10013247 0,11267353 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,10013247 0,11261843 ! regulation of ossification GO:0030278 71 46 0,000 0,10013247 0,11256339 ! histone modification GO:0016570 68 46 0,000 0,10013247 0,1125084 ! response to UV GO:0009411 75 46 0,000 0,10013247 0,11245346 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,10219686 0,11471585 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,10219686 0,1146599 ! endocrine system development GO:0035270 83 47 0,000 0,10219686 0,11460399 ! covalent chromatin modification GO:0016569 75 47 0,000 0,10219686 0,11454814 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,10219686 0,11449235 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,10219686 0,1144366 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,10219686 0,11438092 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,10219686 0,11432529 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,10219686 0,11426971 ! chloride transport GO:0006821 67 48 0,000 0,10425664 0,11651616 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,10425664 0,11645957 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,10425664 0,11640304 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,10425664 0,11634656 ! gastrulation GO:0007369 73 48 0,000 0,10425664 0,11629014 ! heart morphogenesis GO:0003007 65 48 0,000 0,10425664 0,11623377 ! regulation of DNA replication GO:0006275 75 48 0,000 0,10425664 0,11617745 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,10425664 0,11612119 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,10425664 0,11606499 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,10425664 0,11600883 ! regulation of endocytosis GO:0030100 63 48 0,000 0,10425664 0,11595274 ! nuclear export GO:0051168 69 48 0,000 0,10425664 0,11589669 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,10425664 0,11584071 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,10425664 0,11578477 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,1063118 0,1180102 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,1063118 0,11795328 ! sensory perception of smell GO:0007608 61 49 0,000 0,1063118 0,1178964 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,1063118 0,11783959 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,1063118 0,11778282 ! RNA elongation GO:0006354 62 49 0,000 0,1063118 0,11772611 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,1063118 0,11766946 ! cartilage development GO:0051216 70 49 0,000 0,1063118 0,11761286 ! maintenance of location GO:0051235 84 49 0,000 0,1063118 0,11755632 ! ear development GO:0043583 72 50 0,000 0,10836237 0,11976619 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,10836237 0,11970867 ! membrane fusion GO:0006944 80 50 0,000 0,10836237 0,1196512 ! lipid modification GO:0030258 73 50 0,000 0,10836237 0,11959378 ! positive regulation of growth GO:0045927 67 50 0,000 0,10836237 0,11953642 ! proton transport GO:0015992 75 50 0,000 0,10836237 0,11947912 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,10836237 0,11942187 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,11040835 0,12161839 ! hydrogen transport GO:0006818 77 51 0,000 0,11040835 0,12156017 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,11040835 0,12150201 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,11040835 0,1214439 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,11040835 0,12138585 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,11040835 0,12132785 ! adult behavior GO:0030534 80 51 0,000 0,11040835 0,12126991 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,11040835 0,12121203 ! transition metal ion transport GO:0000041 74 52 0,000 0,11244975 0,12339428 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,11244975 0,12333544 ! aging GO:0007568 79 52 0,000 0,11244975 0,12327665 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,11244975 0,12321792 ! establishment of organelle localization GO:0051656 85 52 0,000 0,11244975 0,12315925 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,11448658 0,12533038 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,11448658 0,12527076 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,11448658 0,12521119 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,11448658 0,12515168 ! kidney development GO:0001822 90 53 0,000 0,11448658 0,12509223 ! single fertilization GO:0007338 59 53 0,000 0,11448658 0,12503283 ! cell projection assembly GO:0030031 76 53 0,000 0,11448658 0,12497349 ! amino acid transport GO:0006865 84 54 0,000 0,11651886 0,12713158 ! regulation of mitosis GO:0007088 84 54 0,000 0,11651886 0,1270713 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,11651886 0,12701108 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,11651886 0,12695091 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,11651886 0,1268908 ! DNA catabolic process GO:0006308 67 54 0,000 0,11651886 0,12683075 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,11651886 0,12677075 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,11651886 0,12671081 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,11651886 0,12665093 ! exocytosis GO:0006887 74 55 0,000 0,11854658 0,12879412 ! mesoderm development GO:0007498 76 55 0,000 0,11854658 0,12873331 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,11854658 0,12867256 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,11854658 0,12861186 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,12258844 0,13293418 ! carbohydrate transport GO:0008643 74 57 0,000 0,12258844 0,13287154 ! chromosome segregation GO:0007059 83 57 0,000 0,12258844 0,13280895 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,12258844 0,13274642 ! camera-type eye development GO:0043010 88 57 0,000 0,12258844 0,13268396 ! secondary metabolic process GO:0019748 84 57 0,000 0,12258844 0,13262155 ! developmental maturation GO:0021700 75 57 0,000 0,12258844 0,13255919 ! gonad development GO:0008406 79 57 0,000 0,12258844 0,1324969 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,12460258 0,13461059 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,12460258 0,13454739 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,12460258 0,13448425 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,12460258 0,13442117 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,12661222 0,13652513 ! lung development GO:0030324 94 59 0,000 0,12661222 0,13646115 ! actin filament organization GO:0007015 95 59 0,000 0,12661222 0,13639724 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,12661222 0,13633338 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,12661222 0,13626958 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,12861735 0,13836292 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,12861735 0,13829823 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,12861735 0,13823361 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,12861735 0,13816904 ! regulation of heart contraction GO:0008016 91 60 0,000 0,12861735 0,13810454 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,12861735 0,13804009 ! fertilization GO:0009566 68 60 0,000 0,12861735 0,13797571 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,12861735 0,13791138 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,130618 0,13999134 ! urogenital system development GO:0001655 101 61 0,000 0,130618 0,13992613 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,130618 0,13986099 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,130618 0,13979591 ! extracellular matrix organization GO:0030198 103 61 0,000 0,130618 0,13973089 ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,130618 0,13966593 ! amine catabolic process GO:0009310 90 62 0,000 0,13261417 0,14173448 ! neurotransmitter transport GO:0006836 81 62 0,000 0,13261417 0,14166865 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,13261417 0,14160288 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,13261417 0,14153717 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,13261417 0,14147152 ! organelle localization GO:0051640 96 62 0,000 0,13261417 0,14140593 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,13460587 0,14346317 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,13460587 0,14339672 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,13460587 0,14333033 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,13460587 0,143264 ! regulation of lipase activity GO:0060191 109 63 0,000 0,13460587 0,14319774 ! negative regulation of cell size GO:0045792 108 64 0,000 0,13659312 0,14524465 ! appendage morphogenesis GO:0035107 93 64 0,000 0,13659312 0,14517753 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,13659312 0,14511047 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,13659312 0,14504348 ! hexose catabolic process GO:0019320 82 64 0,000 0,13659312 0,14497654 ! respiratory system development GO:0060541 100 64 0,000 0,13659312 0,14490967 ! adaptive immune response GO:0002250 94 64 0,000 0,13659312 0,14484286 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,13857591 0,14687769 ! regulation of caspase activity GO:0043281 97 65 0,000 0,13857591 0,14681004 ! appendage development GO:0048736 94 65 0,000 0,13857591 0,14674244 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,13857591 0,14667491 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,13857591 0,14660745 ! activation of immune response GO:0002253 83 65 0,000 0,13857591 0,14654004 ! antigen processing and presentation GO:0019882 96 66 0,000 0,14055426 0,14856379 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,14055426 0,14849554 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,14252818 0,15051186 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,14252818 0,15044278 ! acute inflammatory response GO:0002526 92 68 0,000 0,14449769 0,15245169 ! learning or memory GO:0007611 123 68 0,000 0,14449769 0,15238179 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,14449769 0,15231195 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,14449769 0,15224218 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,14449769 0,15217247 ! rhythmic process GO:0048511 105 68 0,000 0,14449769 0,15210283 ! inorganic anion transport GO:0015698 93 68 0,000 0,14449769 0,15203325 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,14646278 0,15403035 ! response to drug GO:0042493 108 69 0,000 0,14646278 0,15395996 ! response to metal ion GO:0010038 103 70 0,000 0,14842347 0,15594974 ! humoral immune response GO:0006959 86 70 0,000 0,14842347 0,15587853 ! eye development GO:0001654 111 70 0,000 0,14842347 0,15580738 ! amine transport GO:0015837 101 70 0,000 0,14842347 0,1557363 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,14842347 0,15566529 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,14842347 0,15559434 ! regulation of catabolic process GO:0009894 106 70 0,000 0,14842347 0,15552345 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,15037976 0,15750157 ! muscle cell differentiation GO:0042692 104 71 0,000 0,15037976 0,15742988 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,15037976 0,15735826 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,15037976 0,1572867 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,15037976 0,15721521 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,15233168 0,15918349 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,15233168 0,1591112 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,15233168 0,15903898 ! regulation of blood pressure GO:0008217 107 73 0,000 0,15427922 0,16099919 ! mitochondrion organization GO:0007005 104 73 0,000 0,15427922 0,16092617 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,15427922 0,16085322 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,15427922 0,16078034 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,1562224 0,16273167 ! digestion GO:0007586 97 74 0,000 0,1562224 0,162658 ! response to inorganic substance GO:0010035 115 75 0,000 0,15816123 0,16460219 ! negative regulation of growth GO:0045926 123 75 0,000 0,15816123 0,16452774 ! response to nutrient GO:0007584 104 75 0,000 0,15816123 0,16445336 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,15816123 0,16437905 ! amine biosynthetic process GO:0009309 97 76 0,000 0,16009571 0,16631443 ! tRNA metabolic process GO:0006399 95 76 0,000 0,16009571 0,16623934 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,16202586 0,16816764 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,16202586 0,16809178 ! regulation of DNA binding GO:0051101 119 77 0,000 0,16202586 0,168016 ! sex differentiation GO:0007548 105 77 0,000 0,16202586 0,16794028 ! protein ubiquitination GO:0016567 125 77 0,000 0,16202586 0,16786463 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,16202586 0,16778905 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,16202586 0,16771354 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,16202586 0,1676381 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,16395169 0,16955435 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,16395169 0,16947815 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,1658732 0,1713874 ! cellular respiration GO:0045333 107 79 0,000 0,1658732 0,17131044 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,1658732 0,17123355 ! regulation of lyase activity GO:0051339 133 79 0,000 0,1658732 0,17115673 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,1658732 0,17107998 ! chromatin assembly GO:0031497 102 80 0,000 0,1677904 0,17297979 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,1677904 0,17290229 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,1677904 0,17282486 ! forebrain development GO:0030900 131 80 0,000 0,1677904 0,1727475 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,1697033 0,17463875 ! mRNA transport GO:0051028 121 81 0,000 0,1697033 0,17456064 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,1697033 0,17448261 ! regulation of neurological system process GO:0031644 122 81 0,000 0,1697033 0,17440465 ! vitamin metabolic process GO:0006766 103 81 0,000 0,1697033 0,17432675 ! ossification GO:0001503 134 82 0,000 0,17161192 0,17620867 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,17351626 0,17808452 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,17351626 0,17800509 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,17351626 0,17792573 ! regulation of defense response GO:0031347 117 84 0,000 0,17541633 0,17979393 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,17541633 0,17971384 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,17541633 0,17963382 ! sterol metabolic process GO:0016125 120 84 0,000 0,17541633 0,17955388 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,17731215 0,18141367 ! rRNA metabolic process GO:0016072 107 85 0,000 0,17731215 0,18133301 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,17731215 0,18125242 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,17731215 0,1811719 ! regulation of membrane potential GO:0042391 128 85 0,000 0,17731215 0,18109145 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,17731215 0,18101107 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,17920371 0,18286093 ! cell cycle arrest GO:0007050 150 86 0,000 0,17920371 0,18277984 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,17920371 0,18269882 ! nucleosome organization GO:0034728 114 87 0,000 0,18109103 0,18454115 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,18109103 0,18445942 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,18109103 0,18437777 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,18109103 0,18429618 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,18297412 0,18613024 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,18297412 0,18604796 ! interphase GO:0051325 159 88 0,000 0,18297412 0,18596574 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,18297412 0,1858836 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,18297412 0,18580154 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,18297412 0,18571954 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,18485299 0,18754384 ! reproductive developmental process GO:0003006 127 89 0,000 0,18485299 0,18746114 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,18485299 0,18737853 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,18485299 0,18729598 ! regulation of T cell activation GO:0050863 128 89 0,000 0,18485299 0,18721351 ! leukocyte differentiation GO:0002521 143 90 0,000 0,18672765 0,18902887 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,18672765 0,1889457 ! RNA localization GO:0006403 135 91 0,000 0,1885981 0,19075445 ! ATP metabolic process GO:0046034 137 91 0,000 0,1885981 0,1906706 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,19046435 0,19247277 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,19046435 0,19238824 ! cell fate commitment GO:0045165 141 92 0,000 0,19046435 0,19230378 ! positive regulation of immune response GO:0050778 121 92 0,000 0,19046435 0,1922194 ! sulfur metabolic process GO:0006790 118 92 0,000 0,19046435 0,19213509 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,19232643 0,19392844 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,19232643 0,19384346 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,19232643 0,19375855 ! electron transport chain GO:0022900 123 94 0,000 0,19418432 0,19554463 ! response to oxidative stress GO:0006979 141 94 0,000 0,19418432 0,19545905 ! regulation of binding GO:0051098 151 95 0,000 0,19603805 0,19723863 ! carboxylic acid transport GO:0046942 147 95 0,000 0,19603805 0,19715239 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,19788762 0,19892549 ! in utero embryonic development GO:0001701 147 96 0,000 0,19788762 0,19883859 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,19788762 0,19875176 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,19788762 0,198665 ! protein maturation GO:0051604 129 96 0,000 0,19788762 0,19857833 ! response to light stimulus GO:0009416 153 96 0,000 0,19788762 0,19849172 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,19973304 0,20025545 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,20341147 0,20385464 ! extracellular structure organization GO:0043062 156 99 0,000 0,20341147 0,20376585 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,2052445 0,20551256 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,2052445 0,20542313 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,2052445 0,20533378 ! divalent metal ion transport GO:0070838 171 100 0,000 0,2052445 0,2052445