pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/187-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 3,000 2,156E-10 5,187E-07 ! organ growth GO:0035265 15 7 3,000 2,156E-10 2,594E-07 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 2,156E-10 1,729E-07 GO:0046676|negative regulation of insulin secretion, ! regulation of growth hormone secretion GO:0060123 16 8 3,000 4,307E-10 2,591E-07 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 7,743E-10 3,726E-07 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 4,307E-09 1,727E-06 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 1,449E-08 4,979E-06 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 2,354E-08 7,078E-06 ! barbed-end actin filament capping GO:0051016 50 23 3,000 5,351E-08 1,431E-05 GO:0051693|actin filament capping, ! regulation of insulin secretion GO:0050796 37 25 3,000 7,626E-08 1,835E-05 ! activation of MAPK activity GO:0000187 115 67 4,000 8,273E-08 1,81E-05 ! negative regulation of actin filament depolymerization GO:0030835 55 26 3,000 9,002E-08 1,805E-05 ! negative regulation of actin filament polymerization GO:0030837 53 26 3,000 9,002E-08 1,666E-05 ! negative regulation of protein polymerization GO:0032272 55 27 3,000 1,056E-07 1,814E-05 ! regulation of actin filament depolymerization GO:0030834 58 28 3,000 1,23E-07 1,973E-05 ! negative regulation of protein complex assembly GO:0031333 59 29 3,000 1,425E-07 2,143E-05 ! regulation of peptide secretion GO:0002791 47 29 3,000 1,425E-07 2,017E-05 ! triglyceride metabolic process GO:0006641 43 31 3,000 1,883E-07 2,517E-05 ! DNA damage checkpoint GO:0000077 71 33 3,000 2,443E-07 3,094E-05 ! negative regulation of secretion GO:0051048 63 35 3,000 3,119E-07 3,752E-05 ! neutral lipid metabolic process GO:0006638 50 35 3,000 3,119E-07 3,574E-05 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 75 36 3,000 3,505E-07 3,833E-05 ! glycerol ether metabolic process GO:0006662 53 37 3,000 3,925E-07 4,106E-05 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 4,313E-07 4,324E-05 ! carbohydrate homeostasis GO:0033500 53 38 3,000 4,381E-07 4,217E-05 GO:0042593|glucose homeostasis, ! organic ether metabolic process GO:0018904 55 39 3,000 4,876E-07 4,513E-05 ! regulation of hormone secretion GO:0046883 62 40 3,000 5,412E-07 4,822E-05 ! hormone-mediated signaling GO:0009755 74 41 3,000 5,99E-07 5,147E-05 ! negative regulation of protein complex disassembly GO:0043242 101 42 3,000 6,612E-07 5,486E-05 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 6,612E-07 5,303E-05 ! regulation of actin filament polymerization GO:0030833 87 45 3,000 8,77E-07 6,807E-05 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 9,594E-07 7,214E-05 ! regulation of protein complex disassembly GO:0043244 113 49 3,000 1,241E-06 9,05E-05 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 3,000 1,707E-06 1,208E-04 ! regulation of protein polymerization GO:0032271 103 53 3,000 1,707E-06 1,174E-04 ! detection of bacterium GO:0016045 18 15 2,000 1,816E-06 1,214E-04 ! negative regulation of cytoskeleton organization GO:0051494 124 54 3,000 1,842E-06 1,198E-04 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 1,984E-06 1,256E-04 ! regulation of actin filament length GO:0030832 105 56 3,000 2,134E-06 1,316E-04 ! negative regulation of immune response GO:0050777 35 16 2,000 2,233E-06 1,343E-04 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,292E-06 1,345E-04 ! positive regulation of secretion GO:0051047 95 59 3,000 2,635E-06 1,509E-04 ! regulation of cellular component size GO:0032535 109 59 3,000 2,635E-06 1,474E-04 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 2,819E-06 1,542E-04 ! regulation of protein complex assembly GO:0043254 117 61 3,000 3,014E-06 1,611E-04 ! multicellular organism reproduction GO:0032504 111 64 3,000 3,656E-06 1,912E-04 GO:0048609|reproductive process in a multicellular organism, ! cell cycle checkpoint GO:0000075 137 69 3,000 4,945E-06 2,531E-04 ! detection of biotic stimulus GO:0009595 29 21 2,000 5,273E-06 2,643E-04 ! regulation of actin cytoskeleton organization GO:0032956 149 74 3,000 6,542E-06 3,212E-04 ! steroid biosynthetic process GO:0006694 131 76 3,000 7,277E-06 3,502E-04 ! regulation of actin filament-based process GO:0032970 152 77 3,000 7,667E-06 3,617E-04 ! lymphocyte proliferation GO:0046651 48 24 2,000 7,997E-06 3,7E-04 ! negative regulation of organelle organization GO:0010639 161 78 3,000 8,072E-06 3,664E-04 ! activation of protein kinase activity GO:0032147 147 79 3,000 8,492E-06 3,784E-04 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,025E-05 4,483E-04 ! leukocyte proliferation GO:0070661 52 26 2,000 1,025E-05 4,403E-04 GO:0032943|mononuclear cell proliferation, ! negative regulation of transport GO:0051051 153 84 3,000 1,084E-05 4,576E-04 ! regulation of protein transport GO:0051223 154 87 3,000 1,246E-05 5,169E-04 GO:0070201|regulation of establishment of protein localization, ! hormone metabolic process GO:0042445 157 97 3,000 1,917E-05 7,816E-04 ! regulation of protein localization GO:0032880 176 97 3,000 1,917E-05 7,686E-04 ! mitotic recombination GO:0006312 9 5 1,000 2,585E-05 1,02E-03 ! porphyrin catabolic process GO:0006787 12 5 1,000 2,585E-05 1,003E-03 GO:0033015|tetrapyrrole catabolic process, ! cellular response to insulin stimulus GO:0032869 82 37 2,000 3,024E-05 1,155E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 3,28E-05 1,233E-03 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 5,417E-05 2,005E-03 ! positive regulation of isotype switching GO:0045830 15 7 1,000 5,417E-05 1,975E-03 GO:0045911|positive regulation of DNA recombination, ! response to insulin stimulus GO:0032868 95 46 2,000 5,848E-05 2,1E-03 ! regulation of JNK cascade GO:0046328 94 47 2,000 6,24E-05 2,208E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 6,648E-05 2,318E-03 ! glycine catabolic process GO:0006546 13 8 1,000 7,216E-05 2,48E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 7,216E-05 2,445E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,216E-05 2,411E-03 ! negative regulation of immune system process GO:0002683 95 50 2,000 7,517E-05 2,477E-03 ! regulation of translational initiation GO:0006446 82 53 2,000 8,953E-05 2,911E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 9,268E-05 2,973E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 9,268E-05 2,934E-03 ! motor axon guidance GO:0008045 16 9 1,000 9,268E-05 2,896E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 9,268E-05 2,859E-03 GO:0002820|negative regulation of adaptive immune response, ! serine family amino acid catabolic process GO:0009071 16 9 1,000 9,268E-05 2,823E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,157E-04 3,48E-03 ! B cell proliferation GO:0042100 18 10 1,000 1,157E-04 3,437E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,157E-04 3,396E-03 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 1,297E-04 3,761E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,363E-04 3,904E-03 ! T cell proliferation GO:0042098 26 11 1,000 1,413E-04 3,999E-03 ! regulation of isotype switching GO:0045191 22 11 1,000 1,413E-04 3,953E-03 ! positive regulation of JNK cascade GO:0046330 23 11 1,000 1,413E-04 3,908E-03 ! germ cell migration GO:0008354 25 11 1,000 1,413E-04 3,863E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 1,413E-04 3,82E-03 ! detection of external stimulus GO:0009581 91 63 2,000 1,5E-04 4,011E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,694E-04 4,478E-03 ! focal adhesion formation GO:0048041 35 12 1,000 1,694E-04 4,43E-03 ! regulation of cellular response to stress GO:0080135 128 67 2,000 1,802E-04 4,662E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2E-04 5,118E-03 GO:0000725|recombinational repair, ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 2,14E-04 5,42E-03 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 2,33E-04 5,841E-03 ! protein-chromophore linkage GO:0018298 19 14 1,000 2,33E-04 5,781E-03 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,067E-04 7,529E-03 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 3,067E-04 7,453E-03 ! glycine metabolic process GO:0006544 28 17 1,000 3,472E-04 8,354E-03 ! DNA unwinding during replication GO:0006268 27 17 1,000 3,472E-04 8,271E-03 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 3,472E-04 8,19E-03 GO:0002712|regulation of B cell mediated immunity, ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 3,472E-04 8,111E-03 ! nitrogen compound catabolic process GO:0044270 143 87 2,000 3,897E-04 9,015E-03 ! patterning of blood vessels GO:0001569 39 18 1,000 3,902E-04 8,941E-03 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,902E-04 8,857E-03 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 3,902E-04 8,774E-03 ! heme metabolic process GO:0042168 36 19 1,000 4,357E-04 9,705E-03 ! DNA duplex unwinding GO:0032508 31 20 1,000 4,836E-04 0,01067384 GO:0032392|DNA geometric change, ! detection of stimulus GO:0051606 151 96 2,000 5,199E-04 0,01137175 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 5,339E-04 0,0115728 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 5,359E-04 0,01151199 ! skeletal muscle tissue development GO:0007519 186 99 2,000 5,688E-04 0,0121106 GO:0060538|skeletal muscle organ development, ! positive regulation of B cell activation GO:0050871 38 22 1,000 5,867E-04 0,01238221 ! regulation of DNA recombination GO:0000018 48 23 1,000 6,419E-04 0,01342958 ! platelet activation GO:0030168 37 23 1,000 6,419E-04 0,01331381 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 6,995E-04 0,01438507 ! porphyrin metabolic process GO:0006778 46 24 1,000 6,995E-04 0,01426316 GO:0033013|tetrapyrrole metabolic process, ! initiation of viral infection GO:0019059 57 26 1,000 8,22E-04 0,0166197 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 8,22E-04 0,0164812 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 8,868E-04 0,01763427 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 9,541E-04 0,01881555 ! respiratory gaseous exchange GO:0007585 57 29 1,000 1,024E-03 0,02002419 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 1,024E-03 0,0198627 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 1,096E-03 0,02108931 ! cell junction assembly GO:0034329 78 30 1,000 1,096E-03 0,02092194 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,096E-03 0,0207572 ! cofactor catabolic process GO:0051187 51 30 1,000 1,096E-03 0,02059503 ! regulation of B cell activation GO:0050864 50 30 1,000 1,096E-03 0,02043538 ! response to heat GO:0009408 50 30 1,000 1,096E-03 0,02027819 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 1,17E-03 0,0214889 ! protein targeting to membrane GO:0006612 68 33 1,000 1,326E-03 0,02416524 ! ceramide metabolic process GO:0006672 64 33 1,000 1,326E-03 0,02398354 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 1,407E-03 0,02526612 ! cell junction organization GO:0034330 86 36 1,000 1,577E-03 0,02810517 ! sphingoid metabolic process GO:0046519 70 36 1,000 1,577E-03 0,02789851 ! meiosis I GO:0007127 65 37 1,000 1,665E-03 0,02924708 ! pigment metabolic process GO:0042440 80 37 1,000 1,665E-03 0,02903515 ! mammary gland development GO:0030879 86 39 1,000 1,849E-03 0,03200601 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 1,849E-03 0,0317774 ! keratinocyte differentiation GO:0030216 62 41 1,000 2,042E-03 0,03484354 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 2,142E-03 0,03629043 ! neuron migration GO:0001764 79 42 1,000 2,142E-03 0,03603665 ! double-strand break repair GO:0006302 81 44 1,000 2,348E-03 0,03923789 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 2,348E-03 0,03896728 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 2,455E-03 0,04045845 ! epidermal cell differentiation GO:0009913 68 46 1,000 2,564E-03 0,04196622 ! regulation of adaptive immune response GO:0002819 84 47 1,000 2,675E-03 0,04349015 ! protein homooligomerization GO:0051260 76 47 1,000 2,675E-03 0,04319827 ! activation of caspase activity GO:0006919 84 48 1,000 2,789E-03 0,04472958 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 2,904E-03 0,04627617 ! response to temperature stimulus GO:0009266 76 49 1,000 2,904E-03 0,04597172 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 2,904E-03 0,04567126 ! viral infectious cycle GO:0019058 99 51 1,000 3,142E-03 0,0490927 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 3,142E-03 0,04877597 ! regulation of cell shape GO:0008360 125 51 1,000 3,142E-03 0,0484633 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 3,265E-03 0,05002897 ! heterocycle catabolic process GO:0046700 85 54 1,000 3,516E-03 0,05353784 ! positive regulation of caspase activity GO:0043280 95 55 1,000 3,645E-03 0,05515159 GO:0010952|positive regulation of peptidase activity, ! positive regulation of cell migration GO:0030335 126 57 1,000 3,909E-03 0,05878176 ! sphingolipid metabolic process GO:0006665 107 61 1,000 4,464E-03 0,06670485 ! viral reproductive process GO:0022415 126 62 1,000 4,608E-03 0,06843203 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 4,754E-03 0,07016949 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 4,754E-03 0,06974163 ! positive regulation of cell motion GO:0051272 146 64 1,000 4,902E-03 0,07148108 ! germ cell development GO:0007281 118 65 1,000 5,052E-03 0,07323028 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 5,36E-03 0,07721641 ! membrane lipid metabolic process GO:0006643 117 68 1,000 5,516E-03 0,07900104 ! negative regulation of ligase activity GO:0051352 112 68 1,000 5,516E-03 0,07853358 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 5,516E-03 0,07807162 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 5,516E-03 0,07761506 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 5,675E-03 0,07938511 ! antigen processing and presentation GO:0019882 104 69 1,000 5,675E-03 0,07892623 ! respiratory tube development GO:0030323 150 70 1,000 5,836E-03 0,08069721 ! amine catabolic process GO:0009310 117 71 1,000 5,999E-03 0,08247648 ! B cell activation GO:0042113 160 71 1,000 5,999E-03 0,08200787 ! regulation of immune effector process GO:0002697 137 71 1,000 5,999E-03 0,08154455 ! regulation of caspase activity GO:0043281 122 72 1,000 6,164E-03 0,08331705 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 6,164E-03 0,08285159 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 6,164E-03 0,0823913 ! axon guidance GO:0007411 139 73 1,000 6,331E-03 0,08415716 ! meiosis GO:0007126 121 74 1,000 6,5E-03 0,08593079 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 6,5E-03 0,08546123 ! cell-matrix adhesion GO:0007160 163 75 1,000 6,671E-03 0,08723528 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 6,671E-03 0,08676374 ! meiotic cell cycle GO:0051321 122 75 1,000 6,671E-03 0,08629727 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 6,845E-03 0,08806467 ! positive regulation of ligase activity GO:0051351 124 77 1,000 7,02E-03 0,08983931 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 7,02E-03 0,08936396 ! blood coagulation GO:0007596 146 78 1,000 7,197E-03 0,09113877 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 1,000 7,197E-03 0,0906616 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 7,376E-03 0,0924365 ! regulation of peptidase activity GO:0052547 134 79 1,000 7,376E-03 0,09195755 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 7,376E-03 0,09148354 ! protein import into nucleus GO:0006606 158 80 1,000 7,558E-03 0,09325177 ! T cell activation GO:0042110 168 81 1,000 7,741E-03 0,09502661 ! response to hypoxia GO:0001666 171 81 1,000 7,741E-03 0,09454424 ! cell-substrate adhesion GO:0031589 171 81 1,000 7,741E-03 0,09406675 ! nuclear import GO:0051170 161 81 1,000 7,741E-03 0,09359405 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 8,109E-03 0,09755186 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 8,109E-03 0,09706653 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,109E-03 0,096586 ! positive regulation of helicase activity GO:0051096 11 5 0,000 8,109E-03 0,09611021 ! neuron fate determination GO:0048664 7 5 0,000 8,109E-03 0,09563908 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,109E-03 0,09517255 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 8,109E-03 0,09471055 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 8,109E-03 0,09425301 ! polyol transport GO:0015791 12 5 0,000 8,109E-03 0,09379987 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 8,109E-03 0,09335107 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,109E-03 0,09290654 ! response to superoxide GO:0000303 10 5 0,000 8,109E-03 0,09246622 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,109E-03 0,09203006 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 8,109E-03 0,09159799 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 8,109E-03 0,09116997 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,109E-03 0,09074592 ! female meiosis GO:0007143 7 5 0,000 8,109E-03 0,0903258 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,109E-03 0,08990955 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,109E-03 0,08949712 ! cobalt ion transport GO:0006824 11 5 0,000 8,109E-03 0,08908846 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 8,109E-03 0,08868351 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 8,109E-03 0,08828223 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 8,109E-03 0,08788456 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,109E-03 0,08749046 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,109E-03 0,08709988 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 8,109E-03 0,08671277 ! embryonic camera-type eye development GO:0031076 10 5 0,000 8,109E-03 0,08632908 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,109E-03 0,08594878 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 8,109E-03 0,08557181 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 8,109E-03 0,08519813 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,109E-03 0,08482771 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,109E-03 0,08446049 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,109E-03 0,08409643 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 8,109E-03 0,0837355 ! negative chemotaxis GO:0050919 14 5 0,000 8,109E-03 0,08337766 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,109E-03 0,08302286 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,109E-03 0,08267107 ! sensory perception of bitter taste GO:0050913 7 5 0,000 8,109E-03 0,08232225 ! behavioral response to pain GO:0048266 9 5 0,000 8,109E-03 0,08197636 ! clathrin coat assembly GO:0048268 14 5 0,000 8,109E-03 0,08163336 ! Notch receptor processing GO:0007220 8 5 0,000 8,109E-03 0,08129322 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,109E-03 0,0809559 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,109E-03 0,08062137 ! micturition GO:0060073 9 5 0,000 8,109E-03 0,0802896 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,109E-03 0,07996054 ! copulation GO:0007620 9 5 0,000 8,109E-03 0,07963417 ! glial cell fate commitment GO:0021781 13 5 0,000 8,109E-03 0,07931046 ! protein maturation by protein folding GO:0022417 13 5 0,000 8,109E-03 0,07898936 ! spermidine metabolic process GO:0008216 7 5 0,000 8,109E-03 0,07867086 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,109E-03 0,07835491 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,109E-03 0,07804149 ! apoptotic cell clearance GO:0043277 20 5 0,000 8,109E-03 0,07773057 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,109E-03 0,07742211 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,109E-03 0,0771161 ! grooming behavior GO:0007625 6 5 0,000 8,109E-03 0,07681249 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,109E-03 0,07651127 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 8,109E-03 0,07621239 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,109E-03 0,07591585 ! response to protozoan GO:0001562 10 5 0,000 8,109E-03 0,0756216 ! positive regulation of glycolysis GO:0045821 14 5 0,000 8,109E-03 0,07532962 ! lymph vessel development GO:0001945 10 5 0,000 8,109E-03 0,07503989 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 8,109E-03 0,07475239 ! endochondral ossification GO:0001958 16 5 0,000 8,109E-03 0,07446707 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,109E-03 0,07418393 ! parathyroid gland development GO:0060017 13 5 0,000 8,109E-03 0,07390293 ! anagen GO:0042640 6 5 0,000 8,109E-03 0,07362405 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,109E-03 0,07334727 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,109E-03 0,07307256 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 8,109E-03 0,0727999 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 8,109E-03 0,07252927 ! dorsal spinal cord development GO:0021516 7 5 0,000 8,109E-03 0,07226064 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 8,109E-03 0,07199399 ! sphingoid catabolic process GO:0046521 6 5 0,000 8,109E-03 0,07172931 ! skeletal myofibril assembly GO:0014866 10 5 0,000 8,109E-03 0,07146657 ! smooth muscle tissue development GO:0048745 28 5 0,000 8,109E-03 0,07120574 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,109E-03 0,07094681 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,109E-03 0,07068976 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,109E-03 0,07043456 ! cardiac muscle fiber development GO:0048739 10 5 0,000 8,109E-03 0,0701812 ! transepithelial chloride transport GO:0030321 9 5 0,000 8,109E-03 0,06992965 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,109E-03 0,0696799 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 8,109E-03 0,06943193 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 8,109E-03 0,06918572 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,109E-03 0,06894125 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,109E-03 0,0686985 ! histidine catabolic process GO:0006548 6 5 0,000 8,109E-03 0,06845745 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 8,109E-03 0,06821809 ! microvillus organization GO:0032528 7 5 0,000 8,109E-03 0,06798039 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 8,109E-03 0,06774435 ! L-serine biosynthetic process GO:0006564 6 5 0,000 8,109E-03 0,06750994 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,109E-03 0,06727715 ! tryptophan metabolic process GO:0006568 9 5 0,000 8,109E-03 0,06704595 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 8,109E-03 0,06681634 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,109E-03 0,0665883 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 8,109E-03 0,06636181 ! polyol catabolic process GO:0046174 7 5 0,000 8,109E-03 0,06613686 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,109E-03 0,06591342 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,109E-03 0,06569149 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,109E-03 0,06547105 ! muscle cell migration GO:0014812 8 5 0,000 8,109E-03 0,06525208 ! mitochondrial fission GO:0000266 8 5 0,000 8,109E-03 0,06503458 ! sister chromatid cohesion GO:0007062 12 5 0,000 8,109E-03 0,06481851 ! mRNA transcription GO:0009299 9 5 0,000 8,109E-03 0,06460388 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 8,109E-03 0,06439067 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 8,109E-03 0,06417886 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 8,109E-03 0,06396843 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,109E-03 0,06375939 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,109E-03 0,0635517 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,109E-03 0,06334537 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,109E-03 0,06314036 ! response to food GO:0032094 6 5 0,000 8,109E-03 0,06293669 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,109E-03 0,06273432 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,109E-03 0,06253325 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 8,109E-03 0,06233346 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,109E-03 0,06213494 ! paraxial mesoderm development GO:0048339 14 5 0,000 8,109E-03 0,06193769 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 8,109E-03 0,06174169 ! forebrain neuron development GO:0021884 13 5 0,000 8,109E-03 0,06154692 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,109E-03 0,06135337 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 8,109E-03 0,06116104 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,109E-03 0,06096991 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,109E-03 0,06077998 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,109E-03 0,06059122 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 8,109E-03 0,06040363 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,109E-03 0,0602172 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 8,109E-03 0,06003192 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 8,109E-03 0,05984777 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,109E-03 0,05966475 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 8,109E-03 0,05948284 ! basic amino acid transport GO:0015802 11 5 0,000 8,109E-03 0,05930204 ! cellular glucose homeostasis GO:0001678 5 5 0,000 8,109E-03 0,05912234 ! early endosome to late endosome transport GO:0045022 12 5 0,000 8,109E-03 0,05894372 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,109E-03 0,05876618 ! depyrimidination GO:0045008 10 5 0,000 8,109E-03 0,05858971 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,109E-03 0,05841429 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,109E-03 0,05823992 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,109E-03 0,05806659 ! zinc ion homeostasis GO:0055069 8 5 0,000 8,109E-03 0,05789428 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 8,109E-03 0,057723 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 8,109E-03 0,05755272 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,109E-03 0,05738345 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,109E-03 0,05721517 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,109E-03 0,05704787 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 8,109E-03 0,05688155 ! peptidyl-arginine modification GO:0018195 9 5 0,000 8,109E-03 0,0567162 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,109E-03 0,0565518 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,109E-03 0,05638836 ! response to arsenic GO:0046685 10 5 0,000 8,109E-03 0,05622586 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 8,109E-03 0,05606429 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 8,109E-03 0,05590365 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 8,109E-03 0,05574392 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 8,109E-03 0,05558511 ! response to cadmium ion GO:0046686 7 5 0,000 8,109E-03 0,05542719 ! bile acid biosynthetic process GO:0006699 6 5 0,000 8,109E-03 0,05527018 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 8,109E-03 0,05511405 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,109E-03 0,0549588 ! decidualization GO:0046697 11 5 0,000 8,109E-03 0,05480442 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 8,109E-03 0,0546509 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 8,109E-03 0,05449825 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,109E-03 0,05434644 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,109E-03 0,05419548 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 8,109E-03 0,05404535 ! base conversion or substitution editing GO:0016553 5 5 0,000 8,109E-03 0,05389606 ! neural tube patterning GO:0021532 7 5 0,000 8,109E-03 0,05374758 ! embryonic cleavage GO:0040016 6 5 0,000 8,109E-03 0,05359992 ! peroxisome fission GO:0016559 5 5 0,000 8,109E-03 0,05345308 ! histone demethylation GO:0016577 10 5 0,000 8,109E-03 0,05330703 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 8,109E-03 0,05316178 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,109E-03 0,05301732 ! metaphase plate congression GO:0051310 7 5 0,000 8,109E-03 0,05287364 ! regulation of sterol transport GO:0032371 7 5 0,000 8,109E-03 0,05273074 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,109E-03 0,05258861 ! enteric nervous system development GO:0048484 8 5 0,000 8,109E-03 0,05244724 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 8,109E-03 0,05230663 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 8,109E-03 0,05216677 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 8,109E-03 0,05202766 ! muscle cell proliferation GO:0033002 11 5 0,000 8,109E-03 0,05188929 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,109E-03 0,05175165 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 8,109E-03 0,05161474 ! plasminogen activation GO:0031639 5 5 0,000 8,109E-03 0,05147856 ! B cell homeostasis GO:0001782 13 5 0,000 8,109E-03 0,05134309 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 8,109E-03 0,05120833 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,109E-03 0,05107427 ! metaphase GO:0051323 8 5 0,000 8,109E-03 0,05094092 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 8,109E-03 0,05080826 ! cellular response to nutrient GO:0031670 8 5 0,000 8,109E-03 0,05067629 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,109E-03 0,05054501 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,109E-03 0,0504144 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,109E-03 0,05028447 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 8,109E-03 0,0501552 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 8,109E-03 0,0500266 ! response to redox state GO:0051775 5 5 0,000 8,109E-03 0,04989865 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 8,109E-03 0,04977136 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 8,109E-03 0,04964471 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,109E-03 0,04951871 ! regulation of telomerase activity GO:0051972 6 5 0,000 8,109E-03 0,04939335 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,109E-03 0,04926862 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 8,109E-03 0,04914452 ! circadian behavior GO:0048512 13 5 0,000 8,109E-03 0,04902104 ! striatum development GO:0021756 9 5 0,000 8,109E-03 0,04889818 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 8,109E-03 0,04877593 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 8,109E-03 0,0486543 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,109E-03 0,04853327 ! glial cell migration GO:0008347 11 5 0,000 8,109E-03 0,04841284 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,109E-03 0,048293 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 8,109E-03 0,04817376 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,109E-03 0,0480551 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,109E-03 0,04793703 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,109E-03 0,04781954 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,109E-03 0,04770262 ! neuroprotection GO:0043526 6 5 0,000 8,109E-03 0,04758627 ! neural plate development GO:0001840 8 5 0,000 8,109E-03 0,04747049 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,109E-03 0,04735527 ! regulation of sensory perception GO:0051931 7 5 0,000 8,109E-03 0,04724061 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,109E-03 0,0471265 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,109E-03 0,04701295 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 8,109E-03 0,04689993 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 8,109E-03 0,04678746 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,109E-03 0,04667553 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,109E-03 0,04656414 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,109E-03 0,04645327 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,109E-03 0,04634293 ! spindle assembly GO:0051225 6 5 0,000 8,109E-03 0,04623311 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 8,109E-03 0,04612381 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,109E-03 0,04601503 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,109E-03 0,04590676 ! drug metabolic process GO:0017144 6 5 0,000 8,109E-03 0,045799 ! stem cell division GO:0017145 11 5 0,000 8,109E-03 0,04569174 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 8,109E-03 0,04558498 ! organ regeneration GO:0031100 7 5 0,000 8,109E-03 0,04547872 ! carnitine metabolic process GO:0009437 7 5 0,000 8,109E-03 0,04537296 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 8,109E-03 0,04526769 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,109E-03 0,0451629 ! response to oxygen levels GO:0070482 176 83 1,000 8,114E-03 0,04508518 ! hemostasis GO:0007599 158 84 1,000 8,303E-03 0,04603088 ! regulation of ligase activity GO:0051340 142 84 1,000 8,303E-03 0,04592506 ! response to unfolded protein GO:0006986 131 85 1,000 8,494E-03 0,04687542 ! positive regulation of cell activation GO:0050867 145 85 1,000 8,494E-03 0,04676816 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 8,688E-03 0,0477231 ! protein localization in nucleus GO:0034504 176 87 1,000 8,883E-03 0,04868448 ! gland development GO:0048732 206 88 1,000 9,08E-03 0,04965222 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 9,279E-03 0,05062622 ! regulation of cell adhesion GO:0030155 212 89 1,000 9,279E-03 0,05051169 ! response to protein stimulus GO:0051789 149 91 1,000 9,684E-03 0,05259275 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,723E-03 0,05268876 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,723E-03 0,05257035 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 9,723E-03 0,05245248 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,723E-03 0,05233514 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,723E-03 0,05221832 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 9,723E-03 0,05210202 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 9,723E-03 0,05198624 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,723E-03 0,05187097 ! sleep GO:0030431 13 6 0,000 9,723E-03 0,05175621 ! response to oxygen radical GO:0000305 11 6 0,000 9,723E-03 0,05164196 ! positive regulation of axon extension GO:0045773 11 6 0,000 9,723E-03 0,05152821 ! myoblast cell fate commitment GO:0048625 16 6 0,000 9,723E-03 0,05141496 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 9,723E-03 0,05130221 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 9,723E-03 0,05118995 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,723E-03 0,05107818 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,723E-03 0,0509669 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 9,723E-03 0,0508561 ! forebrain regionalization GO:0021871 8 6 0,000 9,723E-03 0,05074579 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,723E-03 0,05063595 ! male meiosis GO:0007140 7 6 0,000 9,723E-03 0,05052658 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,723E-03 0,05041769 ! response to zinc ion GO:0010043 9 6 0,000 9,723E-03 0,05030926 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,723E-03 0,0502013 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 9,723E-03 0,05009381 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 9,723E-03 0,04998677 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,723E-03 0,04988019 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,723E-03 0,04977406 ! malate metabolic process GO:0006108 11 6 0,000 9,723E-03 0,04966838 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 9,723E-03 0,04956315 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 9,723E-03 0,04945837 ! protein refolding GO:0042026 15 6 0,000 9,723E-03 0,04935402 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,723E-03 0,04925012 ! opsonization GO:0008228 8 6 0,000 9,723E-03 0,04914665 ! mating behavior GO:0007617 7 6 0,000 9,723E-03 0,04904362 ! neuron remodeling GO:0016322 15 6 0,000 9,723E-03 0,04894102 ! erythrocyte maturation GO:0043249 7 6 0,000 9,723E-03 0,04883885 ! embryonic hemopoiesis GO:0035162 14 6 0,000 9,723E-03 0,0487371 ! equilibrioception GO:0050957 14 6 0,000 9,723E-03 0,04863577 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,723E-03 0,04853487 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 9,723E-03 0,04843438 ! photoreceptor cell development GO:0042461 10 6 0,000 9,723E-03 0,04833431 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,723E-03 0,04823465 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,723E-03 0,04813541 ! response to interferon-gamma GO:0034341 15 6 0,000 9,723E-03 0,04803657 ! toxin metabolic process GO:0009404 11 6 0,000 9,723E-03 0,04793813 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,723E-03 0,0478401 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,723E-03 0,04774246 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 9,723E-03 0,04764523 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 9,723E-03 0,04754839 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 9,723E-03 0,04745194 ! cGMP-mediated signaling GO:0019934 13 6 0,000 9,723E-03 0,04735589 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,723E-03 0,04726022 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 9,723E-03 0,04716493 ! thymic T cell selection GO:0045061 12 6 0,000 9,723E-03 0,04707004 ! protein lipoylation GO:0009249 10 6 0,000 9,723E-03 0,04697552 ! cysteine metabolic process GO:0006534 10 6 0,000 9,723E-03 0,04688138 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,723E-03 0,04678762 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,723E-03 0,04669423 ! glutamate catabolic process GO:0006538 10 6 0,000 9,723E-03 0,04660121 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 9,723E-03 0,04650856 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 9,723E-03 0,04641628 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 9,723E-03 0,04632437 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 9,723E-03 0,04623282 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,723E-03 0,04614163 ! hyperosmotic response GO:0006972 9 6 0,000 9,723E-03 0,0460508 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 9,723E-03 0,04596033 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 9,723E-03 0,04587021 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,723E-03 0,04578045 ! urea metabolic process GO:0019627 7 6 0,000 9,723E-03 0,04569103 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,723E-03 0,04560196 ! neutrophil activation GO:0042119 8 6 0,000 9,723E-03 0,04551324 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,723E-03 0,04542487 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 9,723E-03 0,04533684 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,723E-03 0,04524914 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,723E-03 0,04516179 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,723E-03 0,04507477 ! neuron apoptosis GO:0051402 9 6 0,000 9,723E-03 0,04498809 ! nucleoside salvage GO:0043174 9 6 0,000 9,723E-03 0,04490174 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 9,723E-03 0,04481572 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,723E-03 0,04473003 ! T cell mediated immunity GO:0002456 16 6 0,000 9,723E-03 0,04464467 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,723E-03 0,04455963 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 9,723E-03 0,04447492 ! carnitine transport GO:0015879 10 6 0,000 9,723E-03 0,04439053 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 9,723E-03 0,04430645 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,723E-03 0,0442227 ! positive regulation of exocytosis GO:0045921 8 6 0,000 9,723E-03 0,04413926 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 9,723E-03 0,04405613 ! 5S class rRNA transcription GO:0042791 11 6 0,000 9,723E-03 0,04397332 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,723E-03 0,04389082 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 9,723E-03 0,04380863 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 9,723E-03 0,04372674 ! sodium ion homeostasis GO:0055078 11 6 0,000 9,723E-03 0,04364516 ! establishment of spindle localization GO:0051293 12 6 0,000 9,723E-03 0,04356389 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,723E-03 0,04348291 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,723E-03 0,04340224 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 9,723E-03 0,04332187 ! neural nucleus development GO:0048857 14 6 0,000 9,723E-03 0,04324179 ! response to UV-C GO:0010225 11 6 0,000 9,723E-03 0,04316201 ! astrocyte development GO:0014002 15 6 0,000 9,723E-03 0,04308252 ! protein targeting to lysosome GO:0006622 10 6 0,000 9,723E-03 0,04300332 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,723E-03 0,04292442 ! interaction with symbiont GO:0051702 13 6 0,000 9,723E-03 0,0428458 ! regulation of dendrite development GO:0050773 16 6 0,000 9,723E-03 0,04276747 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,723E-03 0,04268943 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 9,723E-03 0,04261167 ! response to copper ion GO:0046688 10 6 0,000 9,723E-03 0,0425342 ! response to exogenous dsRNA GO:0043330 10 6 0,000 9,723E-03 0,042457 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 9,723E-03 0,04238009 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,723E-03 0,04230345 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,723E-03 0,04222709 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,723E-03 0,042151 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 9,723E-03 0,04207519 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,723E-03 0,04199965 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,723E-03 0,04192439 ! hair follicle maturation GO:0048820 7 6 0,000 9,723E-03 0,04184939 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,723E-03 0,04177466 ! Schwann cell development GO:0014044 15 6 0,000 9,723E-03 0,04170019 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,723E-03 0,04162599 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,723E-03 0,04155206 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 9,723E-03 0,04147838 ! subpallium development GO:0021544 10 6 0,000 9,723E-03 0,04140497 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 9,723E-03 0,04133182 ! histone ubiquitination GO:0016574 8 6 0,000 9,723E-03 0,04125892 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 9,723E-03 0,04118628 ! maintenance of organ identity GO:0048496 9 6 0,000 9,723E-03 0,0411139 ! G2 phase GO:0051319 16 6 0,000 9,723E-03 0,04104177 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 9,723E-03 0,04096989 ! establishment of planar polarity GO:0001736 7 6 0,000 9,723E-03 0,04089826 ! regulation of mast cell activation GO:0033003 12 6 0,000 9,723E-03 0,04082689 ! membrane to membrane docking GO:0022614 14 6 0,000 9,723E-03 0,04075576 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,723E-03 0,04068488 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 9,723E-03 0,04061425 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,723E-03 0,04054386 ! receptor internalization GO:0031623 10 6 0,000 9,723E-03 0,04047372 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 9,723E-03 0,04040381 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 9,723E-03 0,04033415 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,723E-03 0,04026473 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 9,723E-03 0,04019555 ! protein deubiquitination GO:0016579 14 6 0,000 9,723E-03 0,0401266 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 9,723E-03 0,04005789 ! protein destabilization GO:0031648 9 6 0,000 9,723E-03 0,03998941 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,723E-03 0,03992117 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 9,723E-03 0,03985316 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,723E-03 0,03978539 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 9,723E-03 0,03971784 ! progesterone metabolic process GO:0042448 10 6 0,000 9,723E-03 0,03965052 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 9,723E-03 0,03958343 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 9,723E-03 0,03951657 ! negative regulation of axon extension GO:0030517 21 6 0,000 9,723E-03 0,03944993 ! removal of superoxide radicals GO:0019430 11 6 0,000 9,723E-03 0,03938351 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,723E-03 0,03931732 ! determination of adult lifespan GO:0008340 15 6 0,000 9,723E-03 0,03925135 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 9,723E-03 0,03918561 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 9,723E-03 0,03912008 ! cerebellar cortex formation GO:0021697 8 6 0,000 9,723E-03 0,03905477 ! catecholamine transport GO:0051937 9 6 0,000 9,723E-03 0,03898968 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 9,723E-03 0,0389248 ! sensory cilium assembly GO:0035058 10 6 0,000 9,723E-03 0,03886015 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,723E-03 0,0387957 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 9,723E-03 0,03873147 ! maternal placenta development GO:0001893 12 6 0,000 9,723E-03 0,03866745 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 9,723E-03 0,03860364 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,723E-03 0,03854005 ! negative regulation of B cell activation GO:0050869 13 6 0,000 9,723E-03 0,03847666 ! protein amino acid prenylation GO:0018346 16 6 0,000 9,723E-03 0,03841348 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,723E-03 0,0383505 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 9,723E-03 0,03828774 ! positive regulation of coagulation GO:0050820 12 6 0,000 9,723E-03 0,03822518 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,01009544 0,0396242 GO:0010498|proteasomal protein catabolic process, ! female pregnancy GO:0007565 164 94 1,000 0,01030428 0,04037801 ! response to virus GO:0009615 160 98 1,000 0,01115872 0,0436551 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,01115872 0,04358423 GO:0016054|organic acid catabolic process, ! tRNA transcription GO:0009304 14 7 0,000 0,0113346 0,04419944 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0113346 0,04412792 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0113346 0,04405663 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0113346 0,04398557 ! regulation of helicase activity GO:0051095 15 7 0,000 0,0113346 0,04391474 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0113346 0,04384413 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0113346 0,04377376 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0113346 0,04370361 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0113346 0,04363368 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0113346 0,04356398 ! prostate gland development GO:0030850 13 7 0,000 0,0113346 0,0434945 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0113346 0,04342524 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0113346 0,0433562 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0113346 0,04328738 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0113346 0,04321878 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0113346 0,0431504 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0113346 0,04308223 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0113346 0,04301428 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0113346 0,04294654 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0113346 0,04287901 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0113346 0,0428117 ! glycolipid transport GO:0046836 10 7 0,000 0,0113346 0,0427446 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0113346 0,0426777 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,0113346 0,04261102 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,0113346 0,04254454 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0113346 0,04247827 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0113346 0,04241221 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0113346 0,04234635 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0113346 0,0422807 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0113346 0,04221525 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0113346 0,04215 ! mRNA stabilization GO:0048255 18 7 0,000 0,0113346 0,04208496 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0113346 0,04202011 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0113346 0,04195546 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0113346 0,04189102 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0113346 0,04182677 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0113346 0,04176271 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0113346 0,04169886 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0113346 0,04163519 ! lipoprotein transport GO:0042953 14 7 0,000 0,0113346 0,04157173 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0113346 0,04150845 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0113346 0,04144537 ! rhythmic behavior GO:0007622 15 7 0,000 0,0113346 0,04138248 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0113346 0,04131978 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0113346 0,04125726 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0113346 0,04119494 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0113346 0,04113281 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0113346 0,04107086 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0113346 0,0410091 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0113346 0,04094753 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0113346 0,04088613 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0113346 0,04082493 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0113346 0,0407639 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0113346 0,04070306 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0113346 0,0406424 ! spinal cord patterning GO:0021511 13 7 0,000 0,0113346 0,04058192 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0113346 0,04052162 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0113346 0,0404615 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0113346 0,04040156 ! adrenal gland development GO:0030325 17 7 0,000 0,0113346 0,04034179 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0113346 0,0402822 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0113346 0,04022279 ! ovulation GO:0030728 9 7 0,000 0,0113346 0,04016355 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0113346 0,04010449 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0113346 0,0400456 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0113346 0,03998688 ! microtubule nucleation GO:0007020 20 7 0,000 0,0113346 0,03992833 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0113346 0,03986996 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0113346 0,03981175 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0113346 0,03975372 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0113346 0,03969585 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0113346 0,03963816 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0113346 0,03958063 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0113346 0,03952326 ! galactose metabolic process GO:0006012 13 7 0,000 0,0113346 0,03946607 ! vesicle fusion GO:0006906 17 7 0,000 0,0113346 0,03940903 ! response to dietary excess GO:0002021 8 7 0,000 0,0113346 0,03935217 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0113346 0,03929546 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0113346 0,03923892 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0113346 0,03918255 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0113346 0,03912633 ! purine salvage GO:0043101 10 7 0,000 0,0113346 0,03907027 ! nucleoside transport GO:0015858 8 7 0,000 0,0113346 0,03901438 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0113346 0,03895865 ! parturition GO:0007567 14 7 0,000 0,0113346 0,03890307 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0113346 0,03884765 ! rRNA modification GO:0000154 14 7 0,000 0,0113346 0,03879239 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0113346 0,03873729 ! spindle checkpoint GO:0031577 15 7 0,000 0,0113346 0,03868234 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0113346 0,03862755 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0113346 0,03857292 ! macrophage differentiation GO:0030225 11 7 0,000 0,0113346 0,03851843 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0113346 0,03846411 ! centrosome duplication GO:0051298 13 7 0,000 0,0113346 0,03840993 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0113346 0,03835591 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,0113346 0,03830204 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0113346 0,03824832 ! fibrinolysis GO:0042730 10 7 0,000 0,0113346 0,03819475 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0113346 0,03814133 ! eating behavior GO:0042755 7 7 0,000 0,0113346 0,03808806 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0113346 0,03803494 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0113346 0,03798197 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0113346 0,03792914 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0113346 0,03787646 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0113346 0,03782393 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0113346 0,03777154 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0113346 0,0377193 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0113346 0,0376672 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0113346 0,03761524 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0113346 0,03756343 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0113346 0,03751176 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0113346 0,03746024 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0113346 0,03740885 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0113346 0,03735761 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0113346 0,0373065 ! regulation of meiosis GO:0040020 12 7 0,000 0,0113346 0,03725554 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0113346 0,03720471 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0113346 0,03715402 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0113346 0,03710347 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0113346 0,03705306 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0113346 0,03700278 ! transcription termination GO:0006353 13 7 0,000 0,0113346 0,03695264 ! response to tumor cell GO:0002347 13 7 0,000 0,0113346 0,03690264 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,0113346 0,03685277 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0113346 0,03680304 ! anaphase GO:0051322 17 7 0,000 0,0113346 0,03675344 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0113346 0,03670397 ! axonal fasciculation GO:0007413 18 7 0,000 0,0113346 0,03665464 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0113346 0,03660544 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0113346 0,03655637 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0113346 0,03650743 ! diuresis GO:0030146 12 7 0,000 0,0113346 0,03645863 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0113346 0,03640995 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0113346 0,0363614 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0113346 0,03631299 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0113346 0,0362647 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0113346 0,03621654 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0113346 0,0361685 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0113346 0,0361206 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0113346 0,03607282 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0113346 0,03602517 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0113346 0,03597764 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0113346 0,03593024 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0113346 0,03588296 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0113346 0,03583581 ! lymph node development GO:0048535 10 7 0,000 0,0113346 0,03578878 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0113346 0,03574188 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0113346 0,03569509 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0113346 0,03564843 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0113346 0,0356019 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0113346 0,03555548 ! adult feeding behavior GO:0008343 9 7 0,000 0,0113346 0,03550918 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0113346 0,03546301 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0113346 0,03541695 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0113346 0,03537101 ! muscle adaptation GO:0043500 14 7 0,000 0,0113346 0,0353252 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0113346 0,0352795 ! retina homeostasis GO:0001895 12 7 0,000 0,0113346 0,03523392 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0113346 0,03518845 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0113346 0,03514311 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0113346 0,03509788 ! protein prenylation GO:0018342 18 7 0,000 0,0113346 0,03505277 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,0113346 0,03500777 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,0113346 0,03496289 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0113346 0,03491812 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01294352 0,03982368 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01294352 0,03977282 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01294352 0,03972209 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01294352 0,03967148 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01294352 0,03962101 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01294352 0,03957067 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01294352 0,03952045 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01294352 0,03947036 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01294352 0,0394204 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01294352 0,03937056 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01294352 0,03932085 ! meiotic prophase I GO:0007128 13 8 0,000 0,01294352 0,03927127 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01294352 0,03922181 ! oligopeptide transport GO:0006857 15 8 0,000 0,01294352 0,03917247 ! UTP metabolic process GO:0046051 8 8 0,000 0,01294352 0,03912326 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01294352 0,03907417 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01294352 0,03902521 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01294352 0,03897636 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01294352 0,03892764 ! succinate metabolic process GO:0006105 14 8 0,000 0,01294352 0,03887905 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01294352 0,03883057 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01294352 0,03878221 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01294352 0,03873397 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01294352 0,03868586 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01294352 0,03863786 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01294352 0,03858998 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01294352 0,03854222 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01294352 0,03849458 ! reflex GO:0060004 16 8 0,000 0,01294352 0,03844706 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01294352 0,03839965 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01294352 0,03835236 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01294352 0,03830518 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01294352 0,03825813 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01294352 0,03821118 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01294352 0,03816436 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01294352 0,03811764 ! pigment granule organization GO:0048753 16 8 0,000 0,01294352 0,03807105 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01294352 0,03802456 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01294352 0,03797819 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01294352 0,03793193 ! histidine metabolic process GO:0006547 16 8 0,000 0,01294352 0,03788578 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01294352 0,03783975 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01294352 0,03779383 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01294352 0,03774802 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01294352 0,03770232 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01294352 0,03765673 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01294352 0,03761125 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01294352 0,03756588 ! melanin metabolic process GO:0006582 15 8 0,000 0,01294352 0,03752062 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01294352 0,03747547 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01294352 0,03743043 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01294352 0,03738549 ! macrophage activation GO:0042116 12 8 0,000 0,01294352 0,03734067 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01294352 0,03729595 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01294352 0,03725133 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01294352 0,03720683 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01294352 0,03716243 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01294352 0,03711813 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01294352 0,03707395 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01294352 0,03702986 ! osteoblast development GO:0002076 16 8 0,000 0,01294352 0,03698589 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01294352 0,03694201 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01294352 0,03689824 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01294352 0,03685457 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01294352 0,03681101 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01294352 0,03676755 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01294352 0,03672419 ! response to UV-B GO:0010224 16 8 0,000 0,01294352 0,03668094 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01294352 0,03663778 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01294352 0,03659473 ! intermediate filament organization GO:0045109 12 8 0,000 0,01294352 0,03655178 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01294352 0,03650893 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01294352 0,03646618 ! cellular extravasation GO:0045123 12 8 0,000 0,01294352 0,03642353 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01294352 0,03638098 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01294352 0,03633852 ! response to antibiotic GO:0046677 11 8 0,000 0,01294352 0,03629617 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01294352 0,03625392 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01294352 0,03621176 ! DNA topological change GO:0006265 12 8 0,000 0,01294352 0,0361697 ! response to tropane GO:0014073 15 8 0,000 0,01294352 0,03612774 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01294352 0,03608588 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01294352 0,03604411 ! melanosome transport GO:0032402 13 8 0,000 0,01294352 0,03600245 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01294352 0,03596087 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01294352 0,03591939 ! mast cell activation GO:0045576 14 8 0,000 0,01294352 0,03587801 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01294352 0,03583673 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01294352 0,03579553 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01294352 0,03575444 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01294352 0,03571343 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01294352 0,03567253 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01294352 0,03563171 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01294352 0,03559099 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01294352 0,03555036 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01294352 0,03550982 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01294352 0,03546938 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01294352 0,03542903 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01294352 0,03538877 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01294352 0,0353486 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01294352 0,03530852 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01294352 0,03526853 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01294352 0,03522864 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01294352 0,03518883 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01294352 0,03514911 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01294352 0,03510949 ! hormone catabolic process GO:0042447 17 8 0,000 0,01294352 0,03506995 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01294352 0,0350305 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01294352 0,03499114 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01294352 0,03495187 ! ATP catabolic process GO:0006200 11 8 0,000 0,01294352 0,03491269 ! blastocyst growth GO:0001832 19 8 0,000 0,01294352 0,03487359 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01294352 0,03483458 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01294352 0,03479566 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01294352 0,03475683 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01294352 0,03471808 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01294352 0,03467942 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01294352 0,03464084 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01294352 0,03460235 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01294352 0,03456395 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01294352 0,03452563 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01294352 0,03448739 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01294352 0,03444924 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01294352 0,03441118 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01294352 0,0343732 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01294352 0,0343353 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01294352 0,03429748 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01294352 0,03425975 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01454988 0,03846924 ! axon extension GO:0048675 15 9 0,000 0,01454988 0,03842701 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01454988 0,03838488 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01454988 0,03834283 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01454988 0,03830088 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01454988 0,03825902 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01454988 0,03821726 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01454988 0,03817558 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01454988 0,03813399 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01454988 0,0380925 ! phosphate transport GO:0006817 19 9 0,000 0,01454988 0,03805109 ! reproductive behavior GO:0019098 19 9 0,000 0,01454988 0,03800978 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01454988 0,03796855 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01454988 0,03792742 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01454988 0,03788637 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01454988 0,03784541 ! GTP metabolic process GO:0046039 9 9 0,000 0,01454988 0,03780454 ! RNA methylation GO:0001510 15 9 0,000 0,01454988 0,03776376 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01454988 0,03772307 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01454988 0,03768246 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01454988 0,03764194 ! artery development GO:0060840 24 9 0,000 0,01454988 0,03760151 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01454988 0,03756117 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01454988 0,03752091 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01454988 0,03748074 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01454988 0,03744065 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01454988 0,03740065 ! chemosensory behavior GO:0007635 20 9 0,000 0,01454988 0,03736073 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01454988 0,0373209 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01454988 0,03728116 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01454988 0,0372415 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01454988 0,03720192 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01454988 0,03716243 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01454988 0,03712302 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01454988 0,03708369 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01454988 0,03704445 ! protein targeting to ER GO:0045047 22 9 0,000 0,01454988 0,03700529 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01454988 0,03696622 ! T cell selection GO:0045058 23 9 0,000 0,01454988 0,03692722 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01454988 0,03688831 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01454988 0,03684948 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01454988 0,03681073 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01454988 0,03677207 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01454988 0,03673348 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01454988 0,03669498 ! mannose metabolic process GO:0006013 13 9 0,000 0,01454988 0,03665655 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01454988 0,03661821 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01454988 0,03657994 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01454988 0,03654176 ! receptor clustering GO:0043113 18 9 0,000 0,01454988 0,03650366 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01454988 0,03646563 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01454988 0,03642769 ! ruffle organization GO:0031529 15 9 0,000 0,01454988 0,03638982 ! retinol metabolic process GO:0042572 18 9 0,000 0,01454988 0,03635203 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01454988 0,03631432 ! behavioral fear response GO:0001662 22 9 0,000 0,01454988 0,03627669 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01454988 0,03623914 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01454988 0,03620166 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01454988 0,03616426 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,01454988 0,03612694 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01454988 0,0360897 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01454988 0,03605253 ! segment specification GO:0007379 13 9 0,000 0,01454988 0,03601544 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01454988 0,03597842 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01454988 0,03594149 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01454988 0,03590462 ! response to amine stimulus GO:0014075 13 9 0,000 0,01454988 0,03586784 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01454988 0,03583112 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01454988 0,03579449 ! erythrocyte development GO:0048821 15 9 0,000 0,01454988 0,03575792 ! gas homeostasis GO:0033483 16 9 0,000 0,01454988 0,03572144 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01454988 0,03568502 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01454988 0,03564868 ! renal water homeostasis GO:0003091 14 9 0,000 0,01454988 0,03561242 ! postreplication repair GO:0006301 22 9 0,000 0,01454988 0,03557623 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01454988 0,03554011 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01454988 0,03550406 ! icosanoid secretion GO:0032309 15 9 0,000 0,01454988 0,03546809 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01454988 0,03543219 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01454988 0,03539637 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01454988 0,03536061 ! regulation of cell division GO:0051302 15 9 0,000 0,01454988 0,03532493 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01454988 0,03528932 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01454988 0,03525378 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01454988 0,03521832 ! sterol catabolic process GO:0016127 11 9 0,000 0,01454988 0,03518292 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01454988 0,0351476 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01454988 0,03511234 ! S phase GO:0051320 9 9 0,000 0,01454988 0,03507716 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01454988 0,03504205 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01454988 0,03500701 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01454988 0,03497204 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01454988 0,03493713 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01454988 0,0349023 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01454988 0,03486754 ! purine base metabolic process GO:0006144 21 9 0,000 0,01454988 0,03483284 ! pigment granule transport GO:0051904 17 9 0,000 0,01454988 0,03479822 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01454988 0,03476366 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01454988 0,03472917 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01454988 0,03469475 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01454988 0,0346604 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01454988 0,03462612 ! mitochondrion localization GO:0051646 15 9 0,000 0,01454988 0,0345919 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01615367 0,03836697 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01615367 0,03832913 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01615367 0,03829137 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01615367 0,03825368 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01615367 0,03821606 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01615367 0,03817852 ! synapsis GO:0007129 13 10 0,000 0,01615367 0,03814106 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01615367 0,03810366 ! N-glycan processing GO:0006491 20 10 0,000 0,01615367 0,03806634 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01615367 0,0380291 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01615367 0,03799192 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01615367 0,03795482 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01615367 0,03791779 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01615367 0,03788084 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01615367 0,03784395 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01615367 0,03780714 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01615367 0,0377704 ! androgen metabolic process GO:0008209 17 10 0,000 0,01615367 0,03773373 ! phospholipid efflux GO:0033700 16 10 0,000 0,01615367 0,03769713 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01615367 0,0376606 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01615367 0,03762414 ! lung alveolus development GO:0048286 26 10 0,000 0,01615367 0,03758775 ! pathogenesis GO:0009405 13 10 0,000 0,01615367 0,03755144 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01615367 0,03751519 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01615367 0,03747901 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01615367 0,03744291 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01615367 0,03740687 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01615367 0,0373709 ! endoderm development GO:0007492 16 10 0,000 0,01615367 0,037335 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01615367 0,03729917 ! arginine catabolic process GO:0006527 13 10 0,000 0,01615367 0,03726341 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01615367 0,03722772 ! proline metabolic process GO:0006560 13 10 0,000 0,01615367 0,03719209 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01615367 0,03715654 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01615367 0,03712105 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01615367 0,03708563 ! V(D)J recombination GO:0033151 28 10 0,000 0,01615367 0,03705027 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01615367 0,03701499 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01615367 0,03697977 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01615367 0,03694462 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01615367 0,03690953 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01615367 0,03687451 ! multicellular organism growth GO:0035264 18 10 0,000 0,01615367 0,03683956 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01615367 0,03680468 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01615367 0,03676986 ! epithelial cell development GO:0002064 20 10 0,000 0,01615367 0,0367351 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01615367 0,03670041 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01615367 0,03666579 ! macroautophagy GO:0016236 17 10 0,000 0,01615367 0,03663123 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01615367 0,03659674 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01615367 0,03656231 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01615367 0,03652795 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01615367 0,03649365 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01615367 0,03645942 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01615367 0,03642525 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01615367 0,03639114 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01615367 0,0363571 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01615367 0,03632312 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01615367 0,0362892 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01615367 0,03625535 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01615367 0,03622156 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01615367 0,03618784 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01615367 0,03615417 ! response to dsRNA GO:0043331 20 10 0,000 0,01615367 0,03612057 ! DNA ligation GO:0006266 19 10 0,000 0,01615367 0,03608704 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01615367 0,03605356 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01615367 0,03602015 ! melanosome localization GO:0032400 16 10 0,000 0,01615367 0,03598679 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01615367 0,0359535 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01615367 0,03592028 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01615367 0,03588711 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01615367 0,035854 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01615367 0,03582096 ! mRNA cleavage GO:0006379 17 10 0,000 0,01615367 0,03578797 ! protein sumoylation GO:0016925 15 10 0,000 0,01615367 0,03575505 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01615367 0,03572219 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01615367 0,03568938 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01615367 0,03565664 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01615367 0,03562396 ! salivary gland development GO:0007431 27 10 0,000 0,01615367 0,03559133 ! prophase GO:0051324 15 10 0,000 0,01615367 0,03555877 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01615367 0,03552627 ! apical protein localization GO:0045176 15 10 0,000 0,01615367 0,03549382 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01615367 0,03546144 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01615367 0,03542911 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01615367 0,03539685 ! midbrain development GO:0030901 13 10 0,000 0,01615367 0,03536464 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01615367 0,03533249 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01615367 0,0353004 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01615367 0,03526836 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01615367 0,03523639 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01615367 0,03520447 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01615367 0,03517261 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01615367 0,03514081 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01615367 0,03510907 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01615367 0,03507738 ! oocyte development GO:0048599 17 10 0,000 0,01615367 0,03504575 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01615367 0,03501418 ! blastocyst formation GO:0001825 17 10 0,000 0,01615367 0,03498266 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01615367 0,0349512 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01615367 0,0349198 ! activation of innate immune response GO:0002218 12 10 0,000 0,01615367 0,03488845 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01615367 0,03485716 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01615367 0,03482593 ! response to nicotine GO:0035094 20 10 0,000 0,01615367 0,03479475 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01615367 0,03476363 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01615367 0,03473256 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01615367 0,03470155 ! localization within membrane GO:0051668 20 10 0,000 0,01615367 0,0346706 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01775491 0,03807337 ! respiratory burst GO:0045730 17 11 0,000 0,01775491 0,03803946 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01775491 0,03800562 ! neuron fate specification GO:0048665 17 11 0,000 0,01775491 0,03797184 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01775491 0,03793811 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01775491 0,03790445 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01775491 0,03787085 ! thyroid gland development GO:0030878 26 11 0,000 0,01775491 0,0378373 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01775491 0,03780382 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01775491 0,03777039 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01775491 0,03773703 ! response to pain GO:0048265 24 11 0,000 0,01775491 0,03770372 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01775491 0,03767047 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01775491 0,03763728 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01775491 0,03760415 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01775491 0,03757108 ! bone resorption GO:0045453 16 11 0,000 0,01775491 0,03753806 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01775491 0,03750511 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01775491 0,03747221 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01775491 0,03743937 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01775491 0,03740658 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01775491 0,03737385 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01775491 0,03734119 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01775491 0,03730857 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01775491 0,03727602 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01775491 0,03724352 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01775491 0,03721108 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01775491 0,03717869 ! lipid digestion GO:0044241 18 11 0,000 0,01775491 0,03714636 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01775491 0,03711409 ! UV protection GO:0009650 19 11 0,000 0,01775491 0,03708187 ! adult heart development GO:0007512 14 11 0,000 0,01775491 0,03704971 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01775491 0,03701761 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01775491 0,03698556 ! temperature homeostasis GO:0001659 17 11 0,000 0,01775491 0,03695356 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01775491 0,03692162 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01775491 0,03688974 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01775491 0,03685791 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01775491 0,03682613 ! regulation of organ growth GO:0046620 13 11 0,000 0,01775491 0,03679442 ! pigment granule localization GO:0051875 20 11 0,000 0,01775491 0,03676275 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01775491 0,03673114 ! vasoconstriction GO:0042310 18 11 0,000 0,01775491 0,03669958 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01775491 0,03666808 ! embryonic axis specification GO:0000578 18 11 0,000 0,01775491 0,03663663 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01775491 0,03660524 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01775491 0,0365739 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01775491 0,03654261 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01775491 0,03651138 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01775491 0,0364802 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01775491 0,03644908 ! zymogen activation GO:0031638 15 11 0,000 0,01775491 0,036418 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01775491 0,03638698 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01775491 0,03635601 ! nucleosome positioning GO:0016584 15 11 0,000 0,01775491 0,0363251 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01775491 0,03629424 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01775491 0,03626343 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01775491 0,03623267 ! acid secretion GO:0046717 18 11 0,000 0,01775491 0,03620196 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01775491 0,03617131 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01775491 0,03614071 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01775491 0,03611016 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01775491 0,03607966 ! oocyte differentiation GO:0009994 18 11 0,000 0,01775491 0,03604921 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01775491 0,03601882 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01775491 0,03598847 ! cholesterol efflux GO:0033344 19 11 0,000 0,01775491 0,03595818 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01775491 0,03592794 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01775491 0,03589774 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,01775491 0,0358676 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01775491 0,03583751 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01775491 0,03580747 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01775491 0,03577748 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01775491 0,03574754 ! defense response to fungus GO:0050832 13 11 0,000 0,01775491 0,03571766 ! developmental induction GO:0031128 19 11 0,000 0,01775491 0,03568782 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01775491 0,03565803 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01775491 0,03562829 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01775491 0,0355986 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01775491 0,03556896 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01775491 0,03553936 ! nucleus localization GO:0051647 19 11 0,000 0,01775491 0,03550982 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01775491 0,03548033 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0193536 0,03864295 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0193536 0,03861091 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0193536 0,03857892 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0193536 0,03854698 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0193536 0,0385151 ! virus-host interaction GO:0019048 29 12 0,000 0,0193536 0,03848327 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,0193536 0,03845149 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0193536 0,03841976 ! cartilage condensation GO:0001502 20 12 0,000 0,0193536 0,03838809 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0193536 0,03835647 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0193536 0,0383249 ! protein complex disassembly GO:0043241 27 12 0,000 0,0193536 0,03829338 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0193536 0,03826192 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0193536 0,0382305 ! hippocampus development GO:0021766 26 12 0,000 0,0193536 0,03819914 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0193536 0,03816783 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0193536 0,03813657 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0193536 0,03810536 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0193536 0,0380742 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0193536 0,0380431 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0193536 0,03801204 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0193536 0,03798104 ! drug transport GO:0015893 16 12 0,000 0,0193536 0,03795008 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0193536 0,03791918 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0193536 0,03788833 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0193536 0,03785752 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0193536 0,03782677 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0193536 0,03779607 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0193536 0,03776541 ! forebrain cell migration GO:0021885 21 12 0,000 0,0193536 0,03773481 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0193536 0,03770425 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0193536 0,03767375 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0193536 0,03764329 ! entry into host cell GO:0030260 32 12 0,000 0,0193536 0,03761289 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0193536 0,03758253 ! monoamine transport GO:0015844 18 12 0,000 0,0193536 0,03755222 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0193536 0,03752196 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0193536 0,03749175 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0193536 0,03746159 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0193536 0,03743147 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0193536 0,03740141 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0193536 0,03737139 ! protein homotetramerization GO:0051289 21 12 0,000 0,0193536 0,03734142 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0193536 0,0373115 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0193536 0,03728163 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0193536 0,0372518 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0193536 0,03722202 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0193536 0,03719229 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0193536 0,03716261 ! cranial nerve development GO:0021545 20 12 0,000 0,0193536 0,03713298 ! fucose catabolic process GO:0019317 22 12 0,000 0,0193536 0,03710339 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0193536 0,03707385 ! histone acetylation GO:0016573 26 12 0,000 0,0193536 0,03704435 ! histone methylation GO:0016571 26 12 0,000 0,0193536 0,03701491 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0193536 0,03698551 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0193536 0,03695615 ! gland morphogenesis GO:0022612 29 12 0,000 0,0193536 0,03692685 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0193536 0,03689758 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0193536 0,03686837 ! T cell homeostasis GO:0043029 25 12 0,000 0,0193536 0,0368392 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0193536 0,03681008 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0193536 0,036781 ! spleen development GO:0048536 22 12 0,000 0,0193536 0,03675197 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0193536 0,03672299 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0193536 0,03669405 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0193536 0,03666516 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0193536 0,03663631 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0193536 0,03660751 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0193536 0,03657875 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0193536 0,03655004 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0193536 0,03652137 ! response to cold GO:0009409 17 12 0,000 0,0193536 0,03649275 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0193536 0,03646418 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0193536 0,03643564 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02094973 0,03940974 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02094973 0,03937895 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02094973 0,03934821 ! peroxisomal transport GO:0043574 24 13 0,000 0,02094973 0,03931752 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02094973 0,03928687 ! lipid localization GO:0010876 28 13 0,000 0,02094973 0,03925627 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02094973 0,03922572 ! organelle fusion GO:0048284 32 13 0,000 0,02094973 0,03919522 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02094973 0,03916477 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02094973 0,03913436 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02094973 0,039104 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02094973 0,03907369 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02094973 0,03904342 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02094973 0,0390132 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02094973 0,03898303 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02094973 0,0389529 ! methionine metabolic process GO:0006555 27 13 0,000 0,02094973 0,03892282 ! plasma membrane organization GO:0007009 24 13 0,000 0,02094973 0,03889279 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02094973 0,0388628 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02094973 0,03883286 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02094973 0,03880297 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02094973 0,03877312 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02094973 0,03874332 ! response to X-ray GO:0010165 25 13 0,000 0,02094973 0,03871356 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02094973 0,03868385 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02094973 0,03865418 ! exocrine system development GO:0035272 32 13 0,000 0,02094973 0,03862456 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02094973 0,03859499 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02094973 0,03856546 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02094973 0,03853598 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02094973 0,03850654 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02094973 0,03847714 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02094973 0,03844779 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02094973 0,03841849 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02094973 0,03838923 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02094973 0,03836001 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02094973 0,03833084 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02094973 0,03830171 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02094973 0,03827263 ! ribosome assembly GO:0042255 17 13 0,000 0,02094973 0,03824359 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02094973 0,0382146 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02094973 0,03818565 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02094973 0,03815674 ! chromatin silencing GO:0006342 26 13 0,000 0,02094973 0,03812788 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02094973 0,03809906 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02094973 0,03807028 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02094973 0,03804155 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02094973 0,03801286 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02094973 0,03798422 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02094973 0,03795561 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02094973 0,03792705 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02094973 0,03789854 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02094973 0,03787006 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02094973 0,03784163 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02094973 0,03781324 ! embryonic placenta development GO:0001892 23 13 0,000 0,02094973 0,0377849 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02094973 0,0377566 ! insulin secretion GO:0030073 23 13 0,000 0,02094973 0,03772833 ! actin filament polymerization GO:0030041 24 13 0,000 0,02094973 0,03770012 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02094973 0,03767194 ! acrosome reaction GO:0007340 18 13 0,000 0,02094973 0,03764381 ! rRNA transcription GO:0009303 25 14 0,000 0,02254332 0,04047704 ! lactation GO:0007595 26 14 0,000 0,02254332 0,04044686 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02254332 0,04041672 ! reproductive cellular process GO:0048610 20 14 0,000 0,02254332 0,04038662 ! tRNA modification GO:0006400 20 14 0,000 0,02254332 0,04035657 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02254332 0,04032657 ! regulation of S phase GO:0033261 23 14 0,000 0,02254332 0,04029661 ! water transport GO:0006833 21 14 0,000 0,02254332 0,04026669 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02254332 0,04023682 ! non-recombinational repair GO:0000726 25 14 0,000 0,02254332 0,04020699 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02254332 0,04017721 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02254332 0,04014747 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02254332 0,04011778 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02254332 0,04008813 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02254332 0,04005852 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02254332 0,04002896 ! palate development GO:0060021 31 14 0,000 0,02254332 0,03999944 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02254332 0,03996996 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02254332 0,03994053 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02254332 0,03991114 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02254332 0,03988179 ! arginine metabolic process GO:0006525 17 14 0,000 0,02254332 0,03985249 ! regulation of heart rate GO:0002027 24 14 0,000 0,02254332 0,03982323 ! organic alcohol transport GO:0015850 29 14 0,000 0,02254332 0,03979401 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02254332 0,03976484 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02254332 0,0397357 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02254332 0,03970661 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02254332 0,03967757 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02254332 0,03964856 ! L-amino acid transport GO:0015807 30 14 0,000 0,02254332 0,0396196 ! bone mineralization GO:0030282 17 14 0,000 0,02254332 0,03959068 ! stem cell development GO:0048864 43 14 0,000 0,02254332 0,03956181 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02254332 0,03953297 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02254332 0,03950418 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02254332 0,03947543 ! cerebellum development GO:0021549 21 14 0,000 0,02254332 0,03944672 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02254332 0,03941805 ! response to gamma radiation GO:0010332 28 14 0,000 0,02254332 0,03938942 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02254332 0,03936084 ! cofactor transport GO:0051181 26 14 0,000 0,02254332 0,0393323 ! NADP metabolic process GO:0006739 24 14 0,000 0,02254332 0,03930379 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02254332 0,03927533 ! intestinal absorption GO:0050892 25 14 0,000 0,02254332 0,03924691 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02254332 0,03921854 ! oxygen transport GO:0015671 21 14 0,000 0,02254332 0,0391902 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02254332 0,0391619 ! male genitalia development GO:0030539 24 14 0,000 0,02254332 0,03913365 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02254332 0,03910543 ! regulation of axon extension GO:0030516 37 14 0,000 0,02254332 0,03907726 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02254332 0,03904913 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02254332 0,03902103 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02413437 0,041745 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02413437 0,04171502 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02413437 0,04168507 ! superoxide anion generation GO:0042554 20 15 0,000 0,02413437 0,04165517 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02413437 0,04162531 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02413437 0,04159549 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02413437 0,04156571 ! copper ion transport GO:0006825 20 15 0,000 0,02413437 0,04153598 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02413437 0,04150629 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02413437 0,04147664 ! sulfate transport GO:0008272 23 15 0,000 0,02413437 0,04144704 ! response to cAMP GO:0051591 22 15 0,000 0,02413437 0,04141748 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02413437 0,04138796 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02413437 0,04135848 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02413437 0,04132904 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02413437 0,04129965 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02413437 0,04127029 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02413437 0,04124098 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02413437 0,04121171 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02413437 0,04118248 ! pituitary gland development GO:0021983 29 15 0,000 0,02413437 0,0411533 ! vesicle coating GO:0006901 33 15 0,000 0,02413437 0,04112415 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02413437 0,04109505 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02413437 0,04106598 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02413437 0,04103696 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02413437 0,04100798 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02413437 0,04097904 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02413437 0,04095014 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02413437 0,04092128 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02413437 0,04089247 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02413437 0,04086369 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02413437 0,04083495 ! histone deacetylation GO:0016575 20 15 0,000 0,02413437 0,04080626 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02413437 0,0407776 ! tissue regeneration GO:0042246 26 15 0,000 0,02413437 0,04074898 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02413437 0,04072041 ! water homeostasis GO:0030104 27 15 0,000 0,02413437 0,04069187 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02413437 0,04066338 ! muscle maintenance GO:0046716 26 15 0,000 0,02413437 0,04063492 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02413437 0,0406065 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02413437 0,04057813 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02413437 0,04054979 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02413437 0,04052149 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02413437 0,04049324 ! cell killing GO:0001906 29 15 0,000 0,02413437 0,04046502 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02413437 0,04043684 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02413437 0,0404087 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02413437 0,0403806 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02413437 0,04035254 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02413437 0,04032451 ! peptide hormone processing GO:0016486 23 15 0,000 0,02413437 0,04029653 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02572289 0,04291905 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02572289 0,0428893 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02572289 0,0428596 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02572289 0,04282994 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02572289 0,04280032 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02572289 0,04277074 ! bone remodeling GO:0046849 27 16 0,000 0,02572289 0,0427412 ! filopodium assembly GO:0046847 32 16 0,000 0,02572289 0,04271171 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02572289 0,04268225 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02572289 0,04265284 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02572289 0,04262346 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02572289 0,04259412 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02572289 0,04256483 ! startle response GO:0001964 28 16 0,000 0,02572289 0,04253558 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02572289 0,04250636 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02572289 0,04247719 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02572289 0,04244805 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02572289 0,04241896 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02572289 0,04238991 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02572289 0,04236089 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02572289 0,04233192 ! response to osmotic stress GO:0006970 25 16 0,000 0,02572289 0,04230298 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02572289 0,04227409 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02572289 0,04224523 ! fructose metabolic process GO:0006000 25 16 0,000 0,02572289 0,04221641 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02572289 0,04218764 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02572289 0,0421589 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02572289 0,0421302 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02572289 0,04210154 ! axon cargo transport GO:0008088 43 16 0,000 0,02572289 0,04207292 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02572289 0,04204434 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02572289 0,04201579 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02572289 0,04198729 ! DNA replication initiation GO:0006270 27 16 0,000 0,02572289 0,04195882 ! neuron recognition GO:0008038 35 16 0,000 0,02572289 0,0419304 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02572289 0,04190201 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02572289 0,04187366 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02572289 0,04184534 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02572289 0,04181707 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02572289 0,04178883 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02572289 0,04176064 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02572289 0,04173248 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02572289 0,04170436 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02572289 0,04167627 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02572289 0,04164823 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02572289 0,04162022 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02572289 0,04159225 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02572289 0,04156431 ! defense response to virus GO:0051607 37 16 0,000 0,02572289 0,04153642 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02730887 0,04406783 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02730887 0,04403829 ! metencephalon development GO:0022037 30 17 0,000 0,02730887 0,0440088 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02730887 0,04397934 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02730887 0,04394992 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02730887 0,04392054 ! signal complex assembly GO:0007172 41 17 0,000 0,02730887 0,0438912 ! endothelial cell migration GO:0043542 28 17 0,000 0,02730887 0,0438619 ! inositol metabolic process GO:0006020 28 17 0,000 0,02730887 0,04383264 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02730887 0,04380342 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02730887 0,04377424 ! glial cell development GO:0021782 27 17 0,000 0,02730887 0,04374509 ! limbic system development GO:0021761 36 17 0,000 0,02730887 0,04371599 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02730887 0,04368692 ! adult walking behavior GO:0007628 33 17 0,000 0,02730887 0,04365789 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02730887 0,04362891 ! heart looping GO:0001947 30 17 0,000 0,02730887 0,04359995 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02730887 0,04357104 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02730887 0,04354217 ! myoblast differentiation GO:0045445 45 17 0,000 0,02730887 0,04351333 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02730887 0,04348453 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02730887 0,04345577 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02730887 0,04342705 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02730887 0,04339837 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02730887 0,04336972 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02730887 0,04334112 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02730887 0,04331255 ! NAD metabolic process GO:0019674 29 17 0,000 0,02730887 0,04328401 ! membrane budding GO:0006900 37 17 0,000 0,02730887 0,04325552 ! DNA integration GO:0015074 29 17 0,000 0,02730887 0,04322706 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02730887 0,04319864 ! regulation of protein binding GO:0043393 33 17 0,000 0,02730887 0,04317026 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02730887 0,04314191 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02730887 0,0431136 ! genitalia development GO:0048806 30 17 0,000 0,02730887 0,04308533 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02730887 0,0430571 ! neural crest cell migration GO:0001755 37 17 0,000 0,02730887 0,0430289 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02730887 0,04300074 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02730887 0,04297262 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02730887 0,04294453 ! steroid catabolic process GO:0006706 31 17 0,000 0,02730887 0,04291648 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02730887 0,04288847 ! gas transport GO:0015669 25 17 0,000 0,02730887 0,04286049 ! organic cation transport GO:0015695 31 17 0,000 0,02730887 0,04283255 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02730887 0,04280465 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02730887 0,04277678 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02730887 0,04274895 ! microspike assembly GO:0030035 36 17 0,000 0,02730887 0,04272115 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02730887 0,04269339 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02730887 0,04266567 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02889232 0,04511026 ! neuron maturation GO:0042551 42 18 0,000 0,02889232 0,04508101 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02889232 0,04505179 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02889232 0,04502261 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02889232 0,04499347 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02889232 0,04496437 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02889232 0,0449353 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02889232 0,04490627 ! memory GO:0007613 31 18 0,000 0,02889232 0,04487728 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02889232 0,04484833 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02889232 0,04481942 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02889232 0,04479054 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02889232 0,0447617 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02889232 0,04473289 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02889232 0,04470412 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02889232 0,04467539 ! response to retinoic acid GO:0032526 26 18 0,000 0,02889232 0,0446467 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02889232 0,04461804 ! response to fungus GO:0009620 21 18 0,000 0,02889232 0,04458942 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02889232 0,04456084 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02889232 0,0445323 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02889232 0,04450379 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02889232 0,04447531 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02889232 0,04444688 ! vitamin transport GO:0051180 27 18 0,000 0,02889232 0,04441848 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02889232 0,04439011 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02889232 0,04436178 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02889232 0,04433349 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02889232 0,04430523 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02889232 0,04427701 ! nerve development GO:0021675 28 18 0,000 0,02889232 0,04424883 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02889232 0,04422068 ! protein secretion GO:0009306 39 19 0,000 0,03047324 0,04661069 ! positive regulation of translation GO:0045727 30 19 0,000 0,03047324 0,04658108 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03047324 0,0465515 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03047324 0,04652197 ! skin development GO:0043588 36 19 0,000 0,03047324 0,04649247 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03047324 0,046463 ! lipid phosphorylation GO:0046834 35 19 0,000 0,03047324 0,04643358 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03047324 0,04640419 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03047324 0,04637484 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03047324 0,04634552 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03047324 0,04631625 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03047324 0,04628701 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03047324 0,0462578 ! cerebral cortex development GO:0021987 36 19 0,000 0,03047324 0,04622864 ! pigmentation during development GO:0048066 41 19 0,000 0,03047324 0,04619951 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03047324 0,04617042 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03047324 0,04614136 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03047324 0,04611234 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03047324 0,04608336 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03047324 0,04605441 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03047324 0,0460255 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03047324 0,04599662 ! peptide cross-linking GO:0018149 37 19 0,000 0,03047324 0,04596779 ! protein export from nucleus GO:0006611 36 19 0,000 0,03047324 0,04593899 ! heart process GO:0003015 30 19 0,000 0,03047324 0,04591022 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03047324 0,04588149 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03047324 0,0458528 ! visual learning GO:0008542 36 19 0,000 0,03047324 0,04582414 ! cellular pigmentation GO:0033059 36 19 0,000 0,03047324 0,04579552 ! G1 phase GO:0051318 40 19 0,000 0,03047324 0,04576693 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03047324 0,04573838 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03047324 0,04570986 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03047324 0,04568138 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03047324 0,04565294 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03047324 0,04562453 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03047324 0,04559616 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03047324 0,04556782 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03047324 0,04553952 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03047324 0,04551125 ! cilium assembly GO:0042384 37 19 0,000 0,03047324 0,04548301 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03047324 0,04545482 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03205165 0,04777959 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03205165 0,04775001 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03205165 0,04772046 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03205165 0,04769095 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03205165 0,04766147 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03205165 0,04763203 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,03205165 0,04760263 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03205165 0,04757326 ! response to vitamin GO:0033273 31 20 0,000 0,03205165 0,04754393 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03205165 0,04751464 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03205165 0,04748538 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03205165 0,04745616 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03205165 0,04742697 ! response to alkaloid GO:0043279 38 20 0,000 0,03205165 0,04739782 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03205165 0,04736871 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03205165 0,04733963 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03205165 0,04731059 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03205165 0,04728158 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03205165 0,04725261 ! cellular response to starvation GO:0009267 33 20 0,000 0,03205165 0,04722367 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,03205165 0,04719477 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03205165 0,04716591 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03205165 0,04713708 ! body fluid secretion GO:0007589 31 20 0,000 0,03205165 0,04710828 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03205165 0,04707952 ! peptide secretion GO:0002790 35 20 0,000 0,03205165 0,0470508 ! stem cell differentiation GO:0048863 53 20 0,000 0,03205165 0,04702211 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03205165 0,04699346 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,03205165 0,04696484 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03205165 0,04693625 ! sensory perception of pain GO:0019233 30 20 0,000 0,03205165 0,0469077 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03205165 0,04687919 ! diencephalon development GO:0021536 34 20 0,000 0,03205165 0,04685071 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03205165 0,04682226 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03205165 0,04679385 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03205165 0,04676547 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03205165 0,04673713 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03205165 0,04670882 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03205165 0,04668055 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03205165 0,04665231 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03205165 0,0466241 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03205165 0,04659593 ! regulation of glucose import GO:0046324 29 20 0,000 0,03205165 0,04656779 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03205165 0,04653969 ! actin filament-based movement GO:0030048 43 20 0,000 0,03205165 0,04651162 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03205165 0,04648358 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03205165 0,04645558 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03205165 0,04642761 ! negative regulation of translation GO:0017148 29 20 0,000 0,03205165 0,04639968 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03205165 0,04637177 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03205165 0,04634391 ! regulation of cell killing GO:0031341 42 21 0,000 0,03362753 0,0485933 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03362753 0,04856413 ! hormone secretion GO:0046879 38 21 0,000 0,03362753 0,048535 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03362753 0,0485059 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03362753 0,04847684 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03362753 0,04844781 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03362753 0,04841882 ! axis specification GO:0009798 38 21 0,000 0,03362753 0,04838986 ! ovarian follicle development GO:0001541 35 21 0,000 0,03362753 0,04836094 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03362753 0,04833205 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03362753 0,04830319 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03362753 0,04827437 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03362753 0,04824558 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03362753 0,04821683 ! cell aging GO:0007569 44 21 0,000 0,03362753 0,04818811 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03362753 0,04815943 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03362753 0,04813078 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03362753 0,04810217 ! cytolysis GO:0019835 24 21 0,000 0,03362753 0,04807359 ! vasodilation GO:0042311 39 21 0,000 0,03362753 0,04804504 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03362753 0,04801653 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03362753 0,04798805 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03362753 0,0479596 ! oogenesis GO:0048477 36 21 0,000 0,03362753 0,04793119 ! DNA modification GO:0006304 34 21 0,000 0,03362753 0,04790281 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03362753 0,04787446 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03362753 0,04784615 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03362753 0,04781788 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03362753 0,04778963 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03362753 0,04776142 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03362753 0,04773324 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03362753 0,0477051 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03362753 0,04767699 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03362753 0,04764891 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03362753 0,04762086 ! collagen catabolic process GO:0030574 28 21 0,000 0,03362753 0,04759285 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03362753 0,04756487 ! gut development GO:0048565 39 21 0,000 0,03362753 0,04753692 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03520091 0,04973187 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03520091 0,04970269 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03520091 0,04967354 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03520091 0,04964442 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03520091 0,04961534 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03520091 0,04958629 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03520091 0,04955727 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03520091 0,04952829 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03520091 0,04949935 ! regeneration GO:0031099 41 22 0,000 0,03520091 0,04947043 ! keratinization GO:0031424 28 22 0,000 0,03520091 0,04944155 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03520091 0,04941271 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03520091 0,0493839 ! sensory perception of taste GO:0050909 28 22 0,000 0,03520091 0,04935512 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03520091 0,04932637 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,03520091 0,04929766 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03520091 0,04926898 ! vacuolar transport GO:0007034 36 22 0,000 0,03520091 0,04924034 ! lysosome organization GO:0007040 41 22 0,000 0,03520091 0,04921173 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03520091 0,04918315 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03520091 0,0491546 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03520091 0,04912609 ! fucose metabolic process GO:0006004 39 22 0,000 0,03520091 0,04909761 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03520091 0,04906917 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03520091 0,04904075 ! ureteric bud development GO:0001657 43 22 0,000 0,03520091 0,04901237 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03520091 0,04898403 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03520091 0,04895571 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03520091 0,04892743 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,03520091 0,04889918 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03520091 0,04887096 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03520091 0,04884278 ! sarcomere organization GO:0045214 30 22 0,000 0,03520091 0,04881463 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03520091 0,04878651 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03520091 0,04875842 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03520091 0,04873037 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03520091 0,04870235 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,03520091 0,04867436 ! protein stabilization GO:0050821 39 22 0,000 0,03520091 0,0486464 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03677177 0,05078811 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03677177 0,05075897 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03677177 0,05072986 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03677177 0,05070079 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03677177 0,05067175 ! gluconeogenesis GO:0006094 33 23 0,000 0,03677177 0,05064275 ! viral genome replication GO:0019079 41 23 0,000 0,03677177 0,05061378 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03677177 0,05058484 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03677177 0,05055593 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03677177 0,05052706 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03677177 0,05049822 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03677177 0,05046941 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03677177 0,05044064 ! visual behavior GO:0007632 42 23 0,000 0,03677177 0,0504119 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03677177 0,05038319 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,03677177 0,05035451 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03677177 0,05032587 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03677177 0,05029726 ! peroxisome organization GO:0007031 37 23 0,000 0,03677177 0,05026868 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03677177 0,05024014 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03677177 0,05021162 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03677177 0,05018314 ! sex determination GO:0007530 47 23 0,000 0,03677177 0,05015469 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03677177 0,05012628 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03677177 0,05009789 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03677177 0,05006954 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03677177 0,05004122 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03677177 0,05001293 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03677177 0,04998468 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03677177 0,04995645 ! fatty acid transport GO:0015908 44 23 0,000 0,03677177 0,04992826 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03677177 0,0499001 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03677177 0,04987197 ! hormone transport GO:0009914 40 23 0,000 0,03677177 0,04984388 ! cell-cell recognition GO:0009988 25 23 0,000 0,03677177 0,04981581 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03677177 0,04978778 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03677177 0,04975978 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03677177 0,0497318 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03677177 0,04970387 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03677177 0,04967596 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03834013 0,05176563 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03834013 0,0517366 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03834013 0,0517076 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03834013 0,05167863 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03834013 0,05164969 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03834013 0,05162079 ! vesicle docking GO:0048278 47 24 0,000 0,03834013 0,05159192 ! spinal cord development GO:0021510 47 24 0,000 0,03834013 0,05156308 ! vacuole organization GO:0007033 43 24 0,000 0,03834013 0,05153427 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03834013 0,0515055 ! digestive system process GO:0022600 39 24 0,000 0,03834013 0,05147676 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03834013 0,05144805 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03834013 0,05141937 ! regulation of behavior GO:0050795 43 24 0,000 0,03834013 0,05139072 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03834013 0,05136211 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03834013 0,05133353 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03834013 0,05130498 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03834013 0,05127646 ! membrane depolarization GO:0051899 39 24 0,000 0,03834013 0,05124797 ! pallium development GO:0021543 49 24 0,000 0,03834013 0,05121952 ! pentose metabolic process GO:0019321 35 24 0,000 0,03834013 0,05119109 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03834013 0,0511627 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03834013 0,05113434 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03834013 0,05110601 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03834013 0,05107771 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03834013 0,05104945 ! alditol metabolic process GO:0019400 38 24 0,000 0,03834013 0,05102121 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03834013 0,05099301 ! regulation of amine transport GO:0051952 40 24 0,000 0,03834013 0,05096484 ! protein tetramerization GO:0051262 52 24 0,000 0,03834013 0,05093669 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03990599 0,05298775 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,03990599 0,05295852 ! myelination GO:0042552 45 25 0,000 0,03990599 0,05292933 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03990599 0,05290017 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03990599 0,05287104 ! phototransduction GO:0007602 33 25 0,000 0,03990599 0,05284194 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03990599 0,05281287 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03990599 0,05278384 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03990599 0,05275484 ! sperm motility GO:0030317 31 25 0,000 0,03990599 0,05272587 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03990599 0,05269693 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03990599 0,05266802 ! receptor metabolic process GO:0043112 46 25 0,000 0,03990599 0,05263915 ! chromosome condensation GO:0030261 45 25 0,000 0,03990599 0,0526103 ! response to starvation GO:0042594 42 25 0,000 0,03990599 0,05258149 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03990599 0,05255271 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,03990599 0,05252396 ! neural crest cell development GO:0014032 54 25 0,000 0,03990599 0,05249525 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03990599 0,05246656 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03990599 0,0524379 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03990599 0,05240928 ! interaction with host GO:0051701 62 25 0,000 0,03990599 0,05238069 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03990599 0,05235213 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03990599 0,0523236 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03990599 0,0522951 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03990599 0,05226663 ! immunoglobulin production GO:0002377 55 25 0,000 0,03990599 0,0522382 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03990599 0,05220979 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03990599 0,05218141 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03990599 0,05215307 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03990599 0,05212476 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03990599 0,05209647 ! telomere organization GO:0032200 43 25 0,000 0,03990599 0,05206822 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03990599 0,05204 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03990599 0,05201181 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04146935 0,05402017 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04146935 0,05399093 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04146935 0,05396173 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04146935 0,05393257 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04146935 0,05390343 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04146935 0,05387432 ! molting cycle process GO:0022404 50 26 0,000 0,04146935 0,05384525 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04146935 0,05381621 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04146935 0,05378719 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,04146935 0,05375821 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04146935 0,05372927 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04146935 0,05370035 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,04146935 0,05367146 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,04146935 0,05364261 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04146935 0,05361378 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,04146935 0,05358499 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04146935 0,05355622 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04146935 0,05352749 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04146935 0,05349879 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,04146935 0,05347012 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04146935 0,05344148 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,04146935 0,05341287 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04146935 0,05338429 ! blastocyst development GO:0001824 49 26 0,000 0,04146935 0,05335575 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04146935 0,05332723 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04146935 0,05329874 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,04303021 0,05527533 ! neuron fate commitment GO:0048663 48 27 0,000 0,04303021 0,05524583 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04303021 0,05521637 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04303021 0,05518693 ! iron ion transport GO:0006826 59 27 0,000 0,04303021 0,05515753 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04303021 0,05512816 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04303021 0,05509882 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04303021 0,05506951 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04303021 0,05504024 ! fat cell differentiation GO:0045444 50 27 0,000 0,04303021 0,05501099 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04303021 0,05498178 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04303021 0,05495259 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04303021 0,05492344 ! autophagy GO:0006914 41 27 0,000 0,04303021 0,05489432 ! male gonad development GO:0008584 44 27 0,000 0,04303021 0,05486523 ! response to toxin GO:0009636 47 27 0,000 0,04303021 0,05483617 ! primary neural tube formation GO:0014020 51 27 0,000 0,04303021 0,05480714 ! base-excision repair GO:0006284 41 27 0,000 0,04303021 0,05477814 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04303021 0,05474917 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04303021 0,05472024 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04303021 0,05469133 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04303021 0,05466245 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04303021 0,05463361 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04303021 0,05460479 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04303021 0,05457601 ! circadian rhythm GO:0007623 50 28 0,000 0,04458859 0,05652273 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04458859 0,05649296 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04458859 0,05646323 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04458859 0,05643353 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04458859 0,05640386 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,04458859 0,05637422 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04458859 0,05634461 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04458859 0,05631503 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04458859 0,05628549 ! synaptogenesis GO:0007416 42 28 0,000 0,04458859 0,05625597 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,04458859 0,05622649 ! lipid oxidation GO:0034440 43 28 0,000 0,04458859 0,05619703 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04458859 0,05616761 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04458859 0,05613822 ! translational initiation GO:0006413 65 29 0,000 0,04614448 0,05806674 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04614448 0,05803639 ! regulation of pH GO:0006885 43 29 0,000 0,04614448 0,05800607 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04614448 0,05797578 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04614448 0,05794552 ! catechol metabolic process GO:0009712 54 29 0,000 0,04614448 0,05791529 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,04614448 0,05788509 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04614448 0,05785493 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04614448 0,0578248 ! cell fate determination GO:0001709 60 29 0,000 0,04614448 0,0577947 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04614448 0,05776463 ! detection of light stimulus GO:0009583 38 29 0,000 0,04614448 0,05773459 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,04614448 0,05770458 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,04614448 0,0576746 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,04614448 0,05764466 ! tissue homeostasis GO:0001894 48 29 0,000 0,04614448 0,05761474 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,04614448 0,05758486 ! phenol metabolic process GO:0018958 55 30 0,000 0,04769788 0,05949254 ! zinc ion transport GO:0006829 45 30 0,000 0,04769788 0,05946171 ! membrane docking GO:0022406 61 30 0,000 0,04769788 0,05943092 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04769788 0,05940016 ! acute-phase response GO:0006953 49 30 0,000 0,04769788 0,05936943 ! myofibril assembly GO:0030239 47 30 0,000 0,04769788 0,05933873 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04769788 0,05930807 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04769788 0,05927743 ! phospholipid transport GO:0015914 51 30 0,000 0,04769788 0,05924683 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04769788 0,05921626 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04769788 0,05918572 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04769788 0,05915521 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04769788 0,05912473 ! eye morphogenesis GO:0048592 60 30 0,000 0,04769788 0,05909429 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04924881 0,06098438 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04924881 0,06095301 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04924881 0,06092167 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04924881 0,06089036 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04924881 0,06085909 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04924881 0,06082785 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,04924881 0,06079664 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04924881 0,06076546 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04924881 0,06073431 ! ovulation cycle process GO:0022602 49 31 0,000 0,04924881 0,0607032 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04924881 0,06067212 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,04924881 0,06064107 ! peptide transport GO:0015833 55 31 0,000 0,04924881 0,06061005 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04924881 0,06057906 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04924881 0,06054811 ! mesoderm formation GO:0001707 69 31 0,000 0,04924881 0,06051718 ! natural killer cell activation GO:0030101 45 31 0,000 0,04924881 0,06048629 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04924881 0,06045543 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04924881 0,0604246 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04924881 0,0603938 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04924881 0,06036304 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05079727 0,06222924 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05079727 0,06219757 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05079727 0,06216593 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,05079727 0,06213433 ! cholesterol transport GO:0030301 56 32 0,000 0,05079727 0,06210276 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05079727 0,06207122 ! spliceosome assembly GO:0000245 67 32 0,000 0,05079727 0,06203971 ! spindle organization GO:0007051 46 32 0,000 0,05079727 0,06200823 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05079727 0,06197679 ! metanephros development GO:0001656 74 32 0,000 0,05079727 0,06194538 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05079727 0,06191399 ! response to ionizing radiation GO:0010212 65 32 0,000 0,05079727 0,06188265 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05079727 0,06185133 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05079727 0,06182004 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,05079727 0,06178879 ! muscle cell development GO:0055001 49 32 0,000 0,05079727 0,06175757 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05079727 0,06172638 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05079727 0,06169522 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05079727 0,06166409 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,05079727 0,06163299 ! ovulation cycle GO:0042698 51 32 0,000 0,05079727 0,06160193 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05079727 0,06157089 ! BMP signaling pathway GO:0030509 64 32 0,000 0,05079727 0,06153989 ! hindbrain development GO:0030902 61 32 0,000 0,05079727 0,06150892 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,05079727 0,06147798 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05079727 0,06144707 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,05079727 0,06141619 ! gene silencing GO:0016458 65 32 0,000 0,05079727 0,06138535 ! post-embryonic development GO:0009791 69 33 0,000 0,05234325 0,06322182 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,05234325 0,0631901 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,05234325 0,06315841 ! formation of primary germ layer GO:0001704 72 33 0,000 0,05234325 0,06312675 ! cell fate specification GO:0001708 52 33 0,000 0,05234325 0,06309512 ! sterol transport GO:0015918 57 33 0,000 0,05234325 0,06306353 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,05234325 0,06303196 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,05234325 0,06300043 ! adult locomotory behavior GO:0008344 59 33 0,000 0,05234325 0,06296893 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,05234325 0,06293746 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,05234325 0,06290603 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,05388677 0,06472869 ! glial cell differentiation GO:0010001 63 34 0,000 0,05388677 0,06469639 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,05388677 0,06466412 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,05388677 0,06463189 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,05388677 0,06459968 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,05388677 0,06456751 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,05388677 0,06453537 ! mismatch repair GO:0006298 46 34 0,000 0,05388677 0,06450327 ! spermatid development GO:0007286 63 34 0,000 0,05388677 0,06447119 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,05388677 0,06443915 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,05388677 0,06440714 ! placenta development GO:0001890 53 34 0,000 0,05388677 0,06437516 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,05388677 0,06434321 ! regulation of muscle development GO:0048634 70 35 0,000 0,05542782 0,06615047 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,05542782 0,06611767 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,05542782 0,06608491 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,05542782 0,06605218 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,05542782 0,06601948 ! odontogenesis GO:0042476 66 35 0,000 0,05542782 0,06598681 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,05542782 0,06595418 ! female gonad development GO:0008585 58 35 0,000 0,05542782 0,06592157 ! telencephalon development GO:0021537 68 35 0,000 0,05542782 0,065889 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,05542782 0,06585647 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,05542782 0,06582396 ! cytokine production GO:0001816 59 35 0,000 0,05542782 0,06579149 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,05542782 0,06575905 ! neural tube formation GO:0001841 67 35 0,000 0,05542782 0,06572664 ! vesicle localization GO:0051648 64 35 0,000 0,05542782 0,06569426 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,05696642 0,06748459 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,05696642 0,06745138 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,05696642 0,0674182 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,05696642 0,06738506 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,05696642 0,06735194 ! positive regulation of cell development GO:0010720 80 36 0,000 0,05696642 0,06731886 ! regulation of proteolysis GO:0030162 72 36 0,000 0,05696642 0,06728581 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,05696642 0,0672528 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,05696642 0,06721982 ! aerobic respiration GO:0009060 55 36 0,000 0,05696642 0,06718687 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,05696642 0,06715395 ! embryonic organ development GO:0048568 57 36 0,000 0,05696642 0,06712106 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,05696642 0,06708821 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,05696642 0,06705538 ! RNA export from nucleus GO:0006405 56 37 0,000 0,05850256 0,06882991 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05850256 0,06879627 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,05850256 0,06876266 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05850256 0,06872908 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05850256 0,06869554 ! organic anion transport GO:0015711 68 37 0,000 0,05850256 0,06866203 ! tissue remodeling GO:0048771 76 37 0,000 0,05850256 0,06862855 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05850256 0,06859511 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05850256 0,06856169 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05850256 0,06852832 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05850256 0,06849497 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05850256 0,06846165 ! glycogen metabolic process GO:0005977 61 37 0,000 0,05850256 0,06842837 ! spermatid differentiation GO:0048515 66 37 0,000 0,05850256 0,06839512 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,06003625 0,07015406 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,06003625 0,07012001 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,06003625 0,07008599 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,06003625 0,070052 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,06003625 0,07001804 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,06003625 0,06998412 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,06003625 0,06995023 ! lipid homeostasis GO:0055088 67 38 0,000 0,06003625 0,06991637 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,06003625 0,06988254 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,06003625 0,06984875 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,06003625 0,06981499 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,06003625 0,06978126 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,06003625 0,06974757 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,06003625 0,06971391 ! glucan metabolic process GO:0044042 62 38 0,000 0,06003625 0,06968028 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,06156749 0,07142304 ! learning GO:0007612 77 39 0,000 0,06156749 0,07138862 ! ear morphogenesis GO:0042471 60 39 0,000 0,06156749 0,07135423 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,06156749 0,07131988 ! segmentation GO:0035282 67 39 0,000 0,06156749 0,07128556 ! ion transmembrane transport GO:0034220 66 39 0,000 0,06156749 0,07125127 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,06156749 0,07121701 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,06156749 0,07118279 ! RNA modification GO:0009451 57 39 0,000 0,06156749 0,0711486 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,06156749 0,07111444 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,06309629 0,07284533 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,06309629 0,07281039 ! feeding behavior GO:0007631 59 40 0,000 0,06309629 0,07277549 ! negative regulation of binding GO:0051100 72 40 0,000 0,06309629 0,07274062 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,06309629 0,07270578 ! mesenchymal cell development GO:0014031 87 40 0,000 0,06309629 0,07267098 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,06309629 0,07263621 ! maintenance of protein location GO:0045185 91 40 0,000 0,06309629 0,07260147 ! cytokinesis GO:0000910 72 40 0,000 0,06309629 0,07256676 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06462265 0,07428671 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06462265 0,07425124 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06462265 0,0742158 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06462265 0,07418039 ! gliogenesis GO:0042063 88 41 0,000 0,06462265 0,07414501 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06462265 0,07410967 ! T cell differentiation GO:0030217 81 41 0,000 0,06462265 0,07407436 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06462265 0,07403909 ! female gamete generation GO:0007292 61 41 0,000 0,06462265 0,07400385 ! polyol metabolic process GO:0019751 66 41 0,000 0,06462265 0,07396864 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06462265 0,07393347 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06614657 0,07564099 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06614657 0,07560506 ! regulation of tube size GO:0035150 71 42 0,000 0,06614657 0,07556916 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06614657 0,07553329 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,06614657 0,07549746 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,06614657 0,07546166 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06614657 0,0754259 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,06614657 0,07539017 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,06766806 0,07708776 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,06766806 0,07705128 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,06766806 0,07701483 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,06766806 0,07697842 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,06766806 0,07694204 ! glucose transport GO:0015758 65 43 0,000 0,06766806 0,07690569 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,06766806 0,07686938 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,06766806 0,07683311 ! neural tube development GO:0021915 77 43 0,000 0,06766806 0,07679686 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,06766806 0,07676066 ! striated muscle contraction GO:0006941 77 43 0,000 0,06766806 0,07672448 ! phagocytosis GO:0006909 90 43 0,000 0,06766806 0,07668834 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,06766806 0,07665224 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,06918712 0,0783361 ! hexose transport GO:0008645 67 44 0,000 0,06918712 0,07829925 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,06918712 0,07826244 ! male sex differentiation GO:0046661 76 44 0,000 0,06918712 0,07822567 ! biopolymer methylation GO:0043414 84 44 0,000 0,06918712 0,07818892 ! B cell differentiation GO:0030183 107 44 0,000 0,06918712 0,07815221 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,06918712 0,07811554 ! developmental growth GO:0048589 82 44 0,000 0,06918712 0,0780789 ! maintenance of location in cell GO:0051651 97 44 0,000 0,06918712 0,0780423 ! glycolysis GO:0006096 65 45 0,000 0,07070376 0,07971567 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,07070376 0,07967833 ! leukocyte migration GO:0050900 68 45 0,000 0,07070376 0,07964103 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,07070376 0,07960376 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,07070376 0,07956653 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,07070376 0,07952933 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,07070376 0,07949217 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,07070376 0,07945504 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,07070376 0,07941795 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,07070376 0,07938089 ! cell growth GO:0016049 84 45 0,000 0,07070376 0,07934386 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,07221798 0,08100534 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,07221798 0,08096759 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,07221798 0,08092988 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,07221798 0,0808922 ! pigmentation GO:0043473 100 46 0,000 0,07221798 0,08085456 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,07221798 0,08081695 ! positive regulation of defense response GO:0031349 76 47 0,000 0,07372978 0,0824704 ! response to calcium ion GO:0051592 81 47 0,000 0,07372978 0,08243208 ! endosome transport GO:0016197 108 47 0,000 0,07372978 0,08239379 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,07372978 0,08235554 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,07372978 0,08231733 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,07372978 0,08227915 ! JNK cascade GO:0007254 91 47 0,000 0,07372978 0,082241 ! methylation GO:0032259 90 47 0,000 0,07372978 0,08220289 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,07523916 0,08384688 ! mitochondrial transport GO:0006839 82 48 0,000 0,07523916 0,08380807 ! Notch signaling pathway GO:0007219 96 48 0,000 0,07523916 0,08376928 ! cellular component disassembly GO:0022411 86 48 0,000 0,07523916 0,08373054 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,07523916 0,08369183 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,07523916 0,08365315 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,07523916 0,08361451 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,07523916 0,08357591 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,07523916 0,08353734 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,07523916 0,08349881 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07674614 0,08513195 ! regulation of action potential GO:0001508 95 49 0,000 0,07674614 0,08509272 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07674614 0,08505353 ! regulation of ion transport GO:0043269 77 49 0,000 0,07674614 0,08501437 ! peptide metabolic process GO:0006518 76 49 0,000 0,07674614 0,08497525 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07674614 0,08493616 ! endocrine system development GO:0035270 104 49 0,000 0,07674614 0,08489711 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,07674614 0,08485809 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07674614 0,08481911 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07674614 0,08478017 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07825071 0,08640257 ! neuromuscular process GO:0050905 99 50 0,000 0,07825071 0,08636294 ! regulation of ossification GO:0030278 117 50 0,000 0,07825071 0,08632334 ! inner ear development GO:0048839 79 50 0,000 0,07825071 0,08628378 ! histone modification GO:0016570 91 50 0,000 0,07825071 0,08624425 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,07825071 0,08620476 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,07825071 0,08616531 ! positive regulation of binding GO:0051099 78 51 0,000 0,07975288 0,08777924 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,07975288 0,08773911 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,07975288 0,08769901 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,07975288 0,08765894 ! excretion GO:0007588 83 51 0,000 0,07975288 0,08761892 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,07975288 0,08757892 ! chromatin remodeling GO:0006338 109 51 0,000 0,07975288 0,08753897 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,07975288 0,08749905 ! vesicle organization GO:0016050 107 51 0,000 0,07975288 0,08745917 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,07975288 0,08741933 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,07975288 0,08737952 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,08125265 0,08898219 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,08125265 0,08894171 ! membrane fusion GO:0006944 110 52 0,000 0,08125265 0,08890126 ! positive regulation of growth GO:0045927 90 52 0,000 0,08125265 0,08886085 ! covalent chromatin modification GO:0016569 101 52 0,000 0,08125265 0,08882048 ! amino acid activation GO:0043038 92 52 0,000 0,08125265 0,08878014 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,08125265 0,08873984 ! synapse organization GO:0050808 85 52 0,000 0,08125265 0,08869958 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,08275003 0,09029322 ! RNA catabolic process GO:0006401 93 53 0,000 0,08275003 0,09025229 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,08275003 0,0902114 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,08275003 0,09017054 ! cell maturation GO:0048469 100 53 0,000 0,08275003 0,09012972 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,08275003 0,09008894 ! response to UV GO:0009411 104 53 0,000 0,08275003 0,0900482 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,08424501 0,09163359 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,08424501 0,09159218 ! cell recognition GO:0008037 85 54 0,000 0,08424501 0,09155081 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,08424501 0,09150948 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,08424501 0,09146818 ! chloride transport GO:0006821 90 55 0,000 0,08573761 0,09304677 ! glucose catabolic process GO:0006007 82 55 0,000 0,08573761 0,09300482 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,08573761 0,09296291 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08573761 0,09292103 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,08573761 0,09287919 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08573761 0,09283739 ! aging GO:0007568 103 55 0,000 0,08573761 0,09279563 ! gastrulation GO:0007369 112 55 0,000 0,08573761 0,09275391 ! heart morphogenesis GO:0003007 97 55 0,000 0,08573761 0,09271222 ! RNA elongation GO:0006354 79 55 0,000 0,08573761 0,09267057 ! nuclear export GO:0051168 97 55 0,000 0,08573761 0,09262896 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,08573761 0,09258738 ! sensory perception of smell GO:0007608 80 56 0,000 0,08722782 0,0941544 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,08722782 0,09411217 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,08722782 0,09406999 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,08722782 0,09402784 ! regulation of DNA replication GO:0006275 101 56 0,000 0,08722782 0,09398574 ! proton transport GO:0015992 94 56 0,000 0,08722782 0,09394366 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,08722782 0,09390163 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,08871566 0,09546059 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,08871566 0,09541792 ! muscle fiber development GO:0048747 112 57 0,000 0,08871566 0,09537528 ! lipid modification GO:0030258 97 57 0,000 0,08871566 0,09533268 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,08871566 0,09529013 ! maintenance of location GO:0051235 118 57 0,000 0,08871566 0,0952476 ! hydrogen transport GO:0006818 97 58 0,000 0,09020112 0,09679924 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,09020112 0,09675608 ! regulation of endocytosis GO:0030100 91 58 0,000 0,09020112 0,09671297 ! adult behavior GO:0030534 99 58 0,000 0,09020112 0,09666989 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,09020112 0,09662685 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,09168421 0,09817188 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,09168421 0,09812821 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,09168421 0,09808457 ! DNA catabolic process GO:0006308 86 59 0,000 0,09168421 0,09804098 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,09168421 0,09799743 ! establishment of organelle localization GO:0051656 109 59 0,000 0,09168421 0,09795391 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,09316493 0,09949171 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,09316493 0,09944757 ! regulation of heart contraction GO:0008016 110 60 0,000 0,09316493 0,09940347 ! camera-type eye development GO:0043010 116 60 0,000 0,09316493 0,09935941 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,09316493 0,09931538 ! kidney development GO:0001822 122 60 0,000 0,09316493 0,0992714 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,09464328 0,10080201 ! mesoderm development GO:0007498 119 61 0,000 0,09464328 0,10075741 ! tRNA processing GO:0008033 89 61 0,000 0,09464328 0,10071284 ! ear development GO:0043583 103 62 0,000 0,09611928 0,10223828 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09611928 0,1021931 ! gonad development GO:0008406 98 62 0,000 0,09611928 0,10214796 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,09611928 0,10210286 ! regulation of mitosis GO:0007088 105 63 0,000 0,09759291 0,10362249 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,09759291 0,10357678 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,09759291 0,10353111 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,0990642 0,1050456 ! cell redox homeostasis GO:0045454 102 64 0,000 0,0990642 0,10499932 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,0990642 0,10495309 ! single fertilization GO:0007338 75 64 0,000 0,0990642 0,10490689 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,10053313 0,10641562 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,10053313 0,10636883 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,10053313 0,10632207 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,10053313 0,10627536 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,10199972 0,10777836 ! actin filament organization GO:0007015 148 66 0,000 0,10199972 0,10773105 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,10199972 0,10768377 ! extracellular matrix organization GO:0030198 133 66 0,000 0,10199972 0,10763655 ! secondary metabolic process GO:0019748 116 66 0,000 0,10199972 0,10758936 ! developmental maturation GO:0021700 116 66 0,000 0,10199972 0,10754221 ! cell projection assembly GO:0030031 120 66 0,000 0,10199972 0,1074951 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,10346396 0,1089905 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,10346396 0,1089428 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,10346396 0,10889514 ! lung development GO:0030324 144 67 0,000 0,10346396 0,10884753 ! chromosome segregation GO:0007059 113 67 0,000 0,10346396 0,10879995 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,10346396 0,10875242 ! hexose catabolic process GO:0019320 104 67 0,000 0,10346396 0,10870493 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,10346396 0,10865748 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,10346396 0,10861008 ! adaptive immune response GO:0002250 119 67 0,000 0,10346396 0,10856271 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,10346396 0,10851539 ! amino acid transport GO:0006865 125 68 0,000 0,10492587 0,11000071 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,10492587 0,10995281 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,10492587 0,10990494 ! regulation of lipase activity GO:0060191 130 68 0,000 0,10492587 0,10985711 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,10492587 0,10980933 ! negative regulation of cell size GO:0045792 134 69 0,000 0,10638544 0,11128842 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,10638544 0,11124006 ! urogenital system development GO:0001655 137 69 0,000 0,10638544 0,11119173 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,10638544 0,11114345 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,10638544 0,11109521 ! appendage morphogenesis GO:0035107 135 70 0,000 0,10784268 0,11256811 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 0,000 0,10929759 0,11403729 ! appendage development GO:0048736 136 71 0,000 0,10929759 0,11398786 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,10929759 0,11393847 ! acute inflammatory response GO:0002526 113 72 0,000 0,11075018 0,11540274 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,11075018 0,11535278 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,11075018 0,11530287 ! carbohydrate transport GO:0008643 110 72 0,000 0,11075018 0,11525299 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,11075018 0,11520317 ! respiratory system development GO:0060541 153 72 0,000 0,11075018 0,11515338 ! learning or memory GO:0007611 147 73 0,000 0,11220044 0,11661091 ! regulation of blood pressure GO:0008217 125 73 0,000 0,11220044 0,11656056 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,11220044 0,11651026 ! fertilization GO:0009566 90 73 0,000 0,11220044 0,11645999 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,11364839 0,11791204 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,11364839 0,11786122 ! neurotransmitter transport GO:0006836 123 74 0,000 0,11364839 0,11781044 ! exocytosis GO:0006887 133 74 0,000 0,11364839 0,1177597 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,11364839 0,11770901 ! eye development GO:0001654 143 74 0,000 0,11364839 0,11765836 ! organelle localization GO:0051640 136 74 0,000 0,11364839 0,11760775 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,11509403 0,11905255 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,11509403 0,11900139 ! rhythmic process GO:0048511 128 75 0,000 0,11509403 0,11895027 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,11509403 0,1188992 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,11653735 0,12033857 ! defense response to bacterium GO:0042742 89 76 0,000 0,11653735 0,12028695 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,11653735 0,12023536 ! regulation of catabolic process GO:0009894 161 76 0,000 0,11653735 0,12018383 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,11797837 0,12161781 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,11941709 0,12304819 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,11941709 0,12299551 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,12085351 0,12442171 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,12085351 0,12436849 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,12085351 0,12431532 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,12228763 0,12573677 ! response to metal ion GO:0010038 140 80 0,000 0,12228763 0,12568306 ! muscle cell differentiation GO:0042692 159 80 0,000 0,12228763 0,12562939 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,12228763 0,12557577 ! inorganic anion transport GO:0015698 138 80 0,000 0,12228763 0,1255222 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,12371946 0,12693775 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,12371946 0,12688364 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,12371946 0,12682958 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,12371946 0,12677556 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,125149 0,12818582 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,125149 0,12813128 ! response to drug GO:0042493 143 82 0,000 0,125149 0,12807678 ! response to nutrient GO:0007584 125 82 0,000 0,125149 0,12802232 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,125149 0,12796791 ! regulation of lyase activity GO:0051339 160 83 0,000 0,12657626 0,12937234 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,12800124 0,13077324 ! negative regulation of growth GO:0045926 155 84 0,000 0,12800124 0,13071773 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,12800124 0,13066227 ! nucleosome assembly GO:0006334 122 85 0,000 0,12942394 0,13205852 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,12942394 0,13200254 ! amine biosynthetic process GO:0009309 138 86 0,000 0,13084436 0,13339472 ! response to inorganic substance GO:0010035 153 86 0,000 0,13084436 0,13333822 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,13084436 0,13328177 ! chromatin assembly GO:0031497 124 86 0,000 0,13084436 0,13322537 ! mitochondrion organization GO:0007005 148 86 0,000 0,13084436 0,13316901 ! alcohol catabolic process GO:0046164 130 86 0,000 0,13084436 0,1331127 ! amine transport GO:0015837 155 86 0,000 0,13084436 0,13305644 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,13226252 0,13444175 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,13367841 0,13582359 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,13367841 0,13576625 ! regulation of DNA binding GO:0051101 155 88 0,000 0,13367841 0,13570897 ! regulation of neurological system process GO:0031644 148 88 0,000 0,13367841 0,13565173 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,13367841 0,13559454 ! cellular defense response GO:0006968 114 89 0,000 0,13509203 0,13697068 ! ossification GO:0001503 188 90 0,000 0,1365034 0,13834338 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,1365034 0,13828513 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,1365034 0,13822693 ! sex differentiation GO:0007548 145 90 0,000 0,1365034 0,13816878 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,1365034 0,13811067 ! bone development GO:0060348 189 91 0,000 0,13791251 0,13947772 ! sterol metabolic process GO:0016125 152 91 0,000 0,13791251 0,13941912 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,13791251 0,13936056 ! regulation of defense response GO:0031347 149 92 0,000 0,13931937 0,14072309 ! nucleosome organization GO:0034728 138 92 0,000 0,13931937 0,14066403 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,13931937 0,14060503 ! vitamin metabolic process GO:0006766 139 92 0,000 0,13931937 0,14054608 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,14072397 0,14190355 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,14072397 0,14184411 ! regulation of membrane potential GO:0042391 164 93 0,000 0,14072397 0,14178471 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,14072397 0,14172536 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,14212634 0,14307781 ! transcription initiation GO:0006352 153 94 0,000 0,14212634 0,14301797 ! regulation of T cell activation GO:0050863 158 94 0,000 0,14212634 0,14295818 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,14352646 0,14430617 ! forebrain development GO:0030900 188 95 0,000 0,14352646 0,14424589 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,14352646 0,14418566 ! leukocyte differentiation GO:0002521 202 96 0,000 0,14492434 0,1455292 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,14492434 0,14546848 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,14492434 0,14540782 ! positive regulation of immune response GO:0050778 156 96 0,000 0,14492434 0,14534721 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,14631998 0,14668578 ! protein ubiquitination GO:0016567 217 97 0,000 0,14631998 0,14662469 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1477134 0,14795938 ! interphase GO:0051325 213 98 0,000 0,1477134 0,14789781 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,14910459 0,14922863 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,14910459 0,14916658 ! cell cycle arrest GO:0007050 213 100 0,000 0,15049355 0,15049355