pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-pos-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/121-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fructose metabolic process GO:0006000 25 16 5,000 4,28E-11 1,046E-07 ! positive regulation of locomotion GO:0040017 44 22 5,000 3,905E-10 4,769E-07 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 5,000 5,264E-10 4,287E-07 ! regulation of behavior GO:0050795 48 25 5,000 9,17E-10 5,601E-07 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 3,000 1,602E-09 7,827E-07 ! positive regulation of response to external stimulus GO:0032103 88 44 5,000 3,419E-08 1,392E-05 ! regulation of DNA metabolic process GO:0051052 188 97 6,000 2,119E-07 7,395E-05 ! double-strand break repair via homologous recombination GO:0000724 19 13 3,000 2,23E-07 6,811E-05 GO:0000725|recombinational repair, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 5,000 5,317E-07 1,443E-04 ! positive regulation of DNA metabolic process GO:0051054 77 38 4,000 5,996E-07 1,465E-04 ! polyol catabolic process GO:0046174 9 5 2,000 7,619E-07 1,692E-04 GO:0019405|alditol catabolic process, ! ganglioside catabolic process GO:0006689 12 5 2,000 7,619E-07 1,551E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 7,619E-07 1,432E-04 ! double-strand break repair GO:0006302 85 44 4,000 1,271E-06 2,218E-04 ! positive regulation of phosphorylation GO:0042327 149 81 5,000 1,38E-06 2,247E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 1,425E-06 2,175E-04 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 2,000 1,519E-06 2,183E-04 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 5,000 1,594E-06 2,163E-04 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of inflammatory response GO:0050729 41 21 3,000 1,818E-06 2,337E-04 ! alcohol catabolic process GO:0046164 142 87 5,000 2,102E-06 2,568E-04 ! reciprocal meiotic recombination GO:0007131 44 22 3,000 2,214E-06 2,576E-04 ! positive regulation of protein modification process GO:0031401 156 90 5,000 2,565E-06 2,848E-04 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 2,000 2,65E-06 2,815E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 2,65E-06 2,697E-04 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 4,227E-06 4,13E-04 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 2,000 4,227E-06 3,971E-04 GO:0002688|regulation of leukocyte chemotaxis, ! glycolipid catabolic process GO:0019377 16 8 2,000 4,227E-06 3,824E-04 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of protein modification process GO:0031400 66 28 3,000 6,076E-06 5,301E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 6,32E-06 5,324E-04 ! ganglioside metabolic process GO:0001573 22 9 2,000 6,32E-06 5,147E-04 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 2,000 6,32E-06 4,981E-04 ! neuromuscular process controlling posture GO:0050884 15 9 2,000 6,32E-06 4,825E-04 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 2,000 9E-06 6,663E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 9E-06 6,467E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 9E-06 6,282E-04 ! hexose biosynthetic process GO:0019319 53 32 3,000 1,053E-05 7,145E-04 ! leukocyte chemotaxis GO:0030595 55 33 3,000 1,194E-05 7,885E-04 GO:0060326|cell chemotaxis, ! chondrocyte differentiation GO:0002062 27 11 2,000 1,234E-05 7,931E-04 ! positive regulation of leukocyte migration GO:0002687 28 11 2,000 1,234E-05 7,728E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 1,234E-05 7,535E-04 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 22 12 2,000 1,64E-05 9,77E-04 GO:0050927|positive regulation of positive chemotaxis, ! regulation of interleukin-12 production GO:0032655 19 12 2,000 1,64E-05 9,538E-04 ! regulation of leukocyte migration GO:0002685 29 12 2,000 1,64E-05 9,316E-04 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 2,000 1,64E-05 9,104E-04 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 1,7E-05 9,23E-04 ! monosaccharide biosynthetic process GO:0046364 57 36 3,000 1,702E-05 9,039E-04 ! meiosis I GO:0007127 74 38 3,000 2,119E-05 1,101E-03 ! negative regulation of lipid metabolic process GO:0045833 20 13 2,000 2,125E-05 1,082E-03 ! positive regulation of cell growth GO:0030307 24 13 2,000 2,125E-05 1,059E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 2,000 2,125E-05 1,038E-03 ! regulation of RNA splicing GO:0043484 22 13 2,000 2,125E-05 1,018E-03 ! meiosis GO:0007126 143 81 4,000 2,64E-05 1,24E-03 GO:0051327|M phase of meiotic cell cycle, ! hair follicle morphogenesis GO:0031069 27 14 2,000 2,696E-05 1,243E-03 ! lipid localization GO:0010876 32 14 2,000 2,696E-05 1,22E-03 GO:0019915|lipid storage, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 2,696E-05 1,198E-03 ! meiotic cell cycle GO:0051321 144 82 4,000 2,802E-05 1,222E-03 ! alcohol biosynthetic process GO:0046165 65 42 3,000 3,17E-05 1,359E-03 ! negative regulation of transport GO:0051051 164 85 4,000 3,334E-05 1,404E-03 ! regulation of mRNA processing GO:0050684 26 15 2,000 3,359E-05 1,391E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 3,359E-05 1,368E-03 ! muscle maintenance GO:0046716 26 15 2,000 3,359E-05 1,345E-03 ! positive regulation of cell size GO:0045793 29 16 2,000 4,122E-05 1,624E-03 ! stem cell development GO:0048864 46 16 2,000 4,122E-05 1,598E-03 GO:0019827|stem cell maintenance, ! glycolysis GO:0006096 71 46 3,000 4,561E-05 1,741E-03 ! leukocyte migration GO:0050900 75 46 3,000 4,561E-05 1,714E-03 ! negative regulation of cell migration GO:0030336 122 46 3,000 4,561E-05 1,688E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 4,989E-05 1,819E-03 ! positive regulation of defense response GO:0031349 88 48 3,000 5,403E-05 1,941E-03 ! regulation of inflammatory response GO:0050727 84 48 3,000 5,403E-05 1,913E-03 ! negative regulation of multicellular organismal process GO:0051241 174 95 4,000 5,69E-05 1,986E-03 ! adult walking behavior GO:0007628 36 18 2,000 5,968E-05 2,054E-03 ! epidermis morphogenesis GO:0048730 43 18 2,000 5,968E-05 2,025E-03 ! sphingolipid catabolic process GO:0030149 32 18 2,000 5,968E-05 1,997E-03 GO:0046466|membrane lipid catabolic process, ! positive regulation of translation GO:0045727 31 19 2,000 7,065E-05 2,332E-03 ! regulation of lipid biosynthetic process GO:0046890 28 19 2,000 7,065E-05 2,301E-03 ! regulation of endothelial cell migration GO:0010594 45 19 2,000 7,065E-05 2,271E-03 ! DNA-dependent DNA replication GO:0006261 82 52 3,000 7,418E-05 2,353E-03 ! skin development GO:0043588 42 20 2,000 8,286E-05 2,595E-03 ! regulation of glucose import GO:0046324 30 20 2,000 8,286E-05 2,562E-03 GO:0010827|regulation of glucose transport, ! negative regulation of cell motion GO:0051271 142 55 3,000 9,252E-05 2,825E-03 ! glucose catabolic process GO:0006007 88 56 3,000 9,931E-05 2,995E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 9,931E-05 2,959E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,112E-04 3,274E-03 ! stem cell differentiation GO:0048863 57 22 2,000 1,112E-04 3,235E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,14E-04 3,275E-03 ! positive regulation of DNA replication GO:0045740 44 23 2,000 1,275E-04 3,622E-03 ! lysosome organization GO:0007040 47 23 2,000 1,275E-04 3,581E-03 ! regulation of heart contraction GO:0008016 123 61 3,000 1,388E-04 3,853E-03 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 1,453E-04 3,988E-03 ! glycosphingolipid metabolic process GO:0006687 44 24 2,000 1,453E-04 3,943E-03 ! platelet activation GO:0030168 41 24 2,000 1,453E-04 3,9E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 1,646E-04 4,37E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 1,646E-04 4,323E-03 ! vacuole organization GO:0007033 49 25 2,000 1,646E-04 4,277E-03 ! interaction with host GO:0051701 66 25 2,000 1,646E-04 4,232E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 1,777E-04 4,521E-03 ! regulation of collagen biosynthetic process GO:0032965 7 5 1,000 1,801E-04 4,537E-03 ! apoptotic cell clearance GO:0043277 23 5 1,000 1,801E-04 4,491E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 1,000 1,801E-04 4,445E-03 ! response to protozoan GO:0001562 13 5 1,000 1,801E-04 4,401E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 1,801E-04 4,357E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,801E-04 4,315E-03 ! regulation of centrosome cycle GO:0046605 7 5 1,000 1,801E-04 4,273E-03 ! mitotic recombination GO:0006312 9 5 1,000 1,801E-04 4,232E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,801E-04 4,191E-03 ! positive regulation of blood coagulation GO:0030194 12 5 1,000 1,801E-04 4,152E-03 ! positive regulation of macrophage activation GO:0043032 12 5 1,000 1,801E-04 4,113E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 1,801E-04 4,075E-03 GO:0042634|regulation of hair cycle, ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 1,801E-04 4,038E-03 ! myelination GO:0042552 50 26 2,000 1,855E-04 4,119E-03 ! molting cycle process GO:0022404 52 26 2,000 1,855E-04 4,082E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 1,855E-04 4,045E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of blood coagulation GO:0030193 46 26 2,000 1,855E-04 4,009E-03 ! telomere organization GO:0032200 46 26 2,000 1,855E-04 3,974E-03 GO:0000723|telomere maintenance, ! alditol metabolic process GO:0019400 44 26 2,000 1,855E-04 3,94E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 2,08E-04 4,38E-03 ! hexose catabolic process GO:0019320 113 68 3,000 2,116E-04 4,418E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 2,239E-04 4,635E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,322E-04 4,767E-03 ! sperm motility GO:0030317 37 28 2,000 2,322E-04 4,727E-03 ! glycolipid metabolic process GO:0006664 50 28 2,000 2,322E-04 4,688E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 2,367E-04 4,739E-03 ! neuromuscular process controlling balance GO:0050885 67 29 2,000 2,582E-04 5,128E-03 ! positive regulation of DNA repair GO:0045739 9 6 1,000 2,695E-04 5,309E-03 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 2,695E-04 5,266E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 1,000 2,695E-04 5,225E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! negative regulation of platelet activation GO:0010544 9 6 1,000 2,695E-04 5,183E-03 GO:0010543|regulation of platelet activation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 2,695E-04 5,143E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,695E-04 5,103E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 10 6 1,000 2,695E-04 5,064E-03 ! response to UV-C GO:0010225 14 6 1,000 2,695E-04 5,025E-03 ! interaction with symbiont GO:0051702 14 6 1,000 2,695E-04 4,987E-03 ! neutrophil homeostasis GO:0001780 11 6 1,000 2,695E-04 4,95E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 2,695E-04 4,913E-03 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 1,000 2,695E-04 4,876E-03 ! organ or tissue specific immune response GO:0002251 8 6 1,000 2,695E-04 4,84E-03 ! positive regulation of coagulation GO:0050820 13 6 1,000 2,695E-04 4,805E-03 ! regulation of coagulation GO:0050818 52 30 2,000 2,86E-04 5,063E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 2,931E-04 5,151E-03 ! ensheathment of neurons GO:0007272 64 31 2,000 3,156E-04 5,508E-03 GO:0008366|axon ensheathment, ! monosaccharide catabolic process GO:0046365 125 77 3,000 3,413E-04 5,914E-03 ! positive regulation of protein ubiquitination GO:0031398 14 7 1,000 3,762E-04 6,472E-03 ! SMAD protein complex assembly GO:0007183 13 7 1,000 3,762E-04 6,427E-03 ! regulation of odontogenesis GO:0042481 14 7 1,000 3,762E-04 6,382E-03 ! negative regulation of focal adhesion formation GO:0051895 21 7 1,000 3,762E-04 6,338E-03 ! regulation of lipid transport GO:0032368 14 7 1,000 3,762E-04 6,295E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 1,000 3,762E-04 6,252E-03 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 1,000 3,762E-04 6,21E-03 ! defense response to Gram-negative bacterium GO:0050829 10 7 1,000 3,762E-04 6,168E-03 ! response to steroid hormone stimulus GO:0048545 147 79 3,000 3,764E-04 6,131E-03 ! response to hypoxia GO:0001666 178 81 3,000 4,141E-04 6,7E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 4,163E-04 6,69E-03 ! adult locomotory behavior GO:0008344 62 34 2,000 4,163E-04 6,647E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 4,163E-04 6,603E-03 ! ceramide metabolic process GO:0006672 72 35 2,000 4,539E-04 7,153E-03 ! response to oxygen levels GO:0070482 183 83 3,000 4,544E-04 7,115E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 2,000 4,936E-04 7,68E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 5,002E-04 7,734E-03 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 1,000 5,002E-04 7,685E-03 ! multicellular organismal aging GO:0010259 20 8 1,000 5,002E-04 7,637E-03 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 5,002E-04 7,59E-03 ! myeloid cell homeostasis GO:0002262 15 8 1,000 5,002E-04 7,543E-03 ! negative regulation of organic acid transport GO:0032891 13 8 1,000 5,002E-04 7,496E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 1,000 5,002E-04 7,451E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 5,002E-04 7,406E-03 GO:0000076|DNA replication checkpoint, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 5,354E-04 7,88E-03 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 2,000 5,795E-04 8,478E-03 ! sphingoid metabolic process GO:0046519 78 38 2,000 5,795E-04 8,427E-03 ! DNA synthesis during DNA repair GO:0000731 18 9 1,000 6,413E-04 9,27E-03 ! postreplication repair GO:0006301 25 9 1,000 6,413E-04 9,216E-03 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 1,000 6,413E-04 9,162E-03 ! regulation of macrophage activation GO:0043030 17 9 1,000 6,413E-04 9,108E-03 ! mitochondrion localization GO:0051646 18 9 1,000 6,413E-04 9,056E-03 ! regulation of action potential in neuron GO:0019228 80 40 2,000 6,745E-04 9,47E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 3,000 7,271E-04 0,01015036 ! regulation of defense response GO:0031347 171 95 3,000 7,566E-04 0,0105016 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 2,000 7,788E-04 0,01074966 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 7,993E-04 0,0109708 ! positive regulation of survival gene product expression GO:0045885 26 10 1,000 7,993E-04 0,01090951 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 7,993E-04 0,0108489 ! B cell proliferation GO:0042100 19 10 1,000 7,993E-04 0,01078897 ! phagocytosis, engulfment GO:0006911 33 10 1,000 7,993E-04 0,01072969 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 7,993E-04 0,01067105 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 7,993E-04 0,01061306 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 7,993E-04 0,01055569 ! salivary gland development GO:0007431 28 10 1,000 7,993E-04 0,01049894 ! positive regulation of acute inflammatory response GO:0002675 18 10 1,000 7,993E-04 0,0104428 ! detection of calcium ion GO:0005513 24 10 1,000 7,993E-04 0,01038725 ! regulation of fibrinolysis GO:0051917 20 10 1,000 7,993E-04 0,01033229 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 8,929E-04 0,01148093 ! striated muscle contraction GO:0006941 85 44 2,000 8,929E-04 0,01142082 ! polyol metabolic process GO:0019751 77 45 2,000 9,537E-04 0,01213488 ! negative regulation of muscle development GO:0048635 27 11 1,000 9,742E-04 0,01233193 ! keratinocyte proliferation GO:0043616 19 11 1,000 9,742E-04 0,01226836 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 9,742E-04 0,01220544 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 9,742E-04 0,01214317 ! telomere maintenance via telomerase GO:0007004 24 11 1,000 9,742E-04 0,01208153 GO:0010833|telomere maintenance via telomere lengthening, ! substrate-bound cell migration GO:0006929 14 11 1,000 9,742E-04 0,01202051 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 9,742E-04 0,01196011 ! alpha-beta T cell activation GO:0046631 26 11 1,000 9,742E-04 0,01190031 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 1,000 9,742E-04 0,0118411 ! regulation of organic acid transport GO:0032890 19 11 1,000 9,742E-04 0,01178248 ! positive regulation of protein transport GO:0051222 80 46 2,000 1,017E-03 0,01223978 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 1,152E-03 0,01379116 ! virus-host interaction GO:0019048 30 12 1,000 1,166E-03 0,01389299 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,166E-03 0,01382554 ! negative regulation of endothelial cell migration GO:0010596 26 12 1,000 1,166E-03 0,01375875 ! mRNA polyadenylation GO:0006378 24 12 1,000 1,166E-03 0,01369261 ! defense response to Gram-positive bacterium GO:0050830 14 12 1,000 1,166E-03 0,01362709 ! response to calcium ion GO:0051592 94 49 2,000 1,223E-03 0,01422637 ! protein homooligomerization GO:0051260 84 49 2,000 1,223E-03 0,01415894 ! regulation of action potential GO:0001508 102 50 2,000 1,297E-03 0,01494493 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,297E-03 0,01487477 ! positive regulation of cytokine production GO:0001819 94 50 2,000 1,297E-03 0,01480526 ! response to temperature stimulus GO:0009266 84 51 2,000 1,374E-03 0,01560863 ! regulation of chemokine production GO:0032642 18 13 1,000 1,374E-03 0,01553913 ! endocrine pancreas development GO:0031018 25 13 1,000 1,374E-03 0,01546753 ! exocrine system development GO:0035272 34 13 1,000 1,374E-03 0,01539657 ! L-glutamate transport GO:0015813 30 13 1,000 1,374E-03 0,01532627 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 1,374E-03 0,0152566 ! regulation of DNA repair GO:0006282 23 13 1,000 1,374E-03 0,01518757 ! gland morphogenesis GO:0022612 31 13 1,000 1,374E-03 0,01511916 ! regulation of acute inflammatory response GO:0002673 24 13 1,000 1,374E-03 0,01505136 ! regulation of epidermis development GO:0045682 19 13 1,000 1,374E-03 0,01498417 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 1,000 1,374E-03 0,01491757 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,374E-03 0,01485156 ! mRNA 3'-end processing GO:0031124 25 13 1,000 1,374E-03 0,01478614 ! positive regulation of growth GO:0045927 96 53 2,000 1,536E-03 0,01645401 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 1,536E-03 0,01638216 ! cartilage development GO:0051216 99 53 2,000 1,536E-03 0,01631093 ! RNA polyadenylation GO:0043631 32 14 1,000 1,598E-03 0,01690426 ! negative regulation of caspase activity GO:0043154 23 14 1,000 1,598E-03 0,0168314 ! RNA-dependent DNA replication GO:0006278 28 14 1,000 1,598E-03 0,01675916 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 1,000 1,598E-03 0,01668754 ! regulation of T-helper 2 type immune response GO:0002828 25 14 1,000 1,598E-03 0,01661653 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,598E-03 0,01654612 ! regulation of angiogenesis GO:0045765 125 54 2,000 1,621E-03 0,01670811 ! neuromuscular process GO:0050905 107 54 2,000 1,621E-03 0,01663791 ! regulation of muscle contraction GO:0006937 94 54 2,000 1,621E-03 0,01656829 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 2,000 1,621E-03 0,01649926 ! regulation of cell shape GO:0008360 142 54 2,000 1,621E-03 0,0164308 ! superoxide anion generation GO:0042554 22 15 1,000 1,839E-03 0,01856616 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 1,000 1,839E-03 0,01848975 ! response to hexose stimulus GO:0009746 25 15 1,000 1,839E-03 0,01841397 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 33 15 1,000 1,839E-03 0,01833882 ! regulation of exocytosis GO:0017157 26 15 1,000 1,839E-03 0,01826427 ! cell killing GO:0001906 32 15 1,000 1,839E-03 0,01819032 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 2,096E-03 0,02064711 ! dicarboxylic acid transport GO:0006835 47 16 1,000 2,096E-03 0,02056419 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,096E-03 0,02048193 ! DNA replication initiation GO:0006270 28 16 1,000 2,096E-03 0,02040033 ! regulation of T-helper cell differentiation GO:0045622 30 16 1,000 2,096E-03 0,02031938 ! adult behavior GO:0030534 104 60 2,000 2,195E-03 0,02119297 ! glycosaminoglycan metabolic process GO:0030203 108 61 2,000 2,301E-03 0,02213237 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 2,301E-03 0,02204557 ! negative regulation of hormone secretion GO:0046888 26 17 1,000 2,369E-03 0,02260532 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,369E-03 0,02251737 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 2,369E-03 0,02243009 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 2,369E-03 0,02234349 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,369E-03 0,02225755 ! regulation of survival gene product expression GO:0045884 38 17 1,000 2,369E-03 0,02217227 ! DNA unwinding during replication GO:0006268 26 17 1,000 2,369E-03 0,02208765 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 1,000 2,369E-03 0,02200366 ! negative regulation of blood coagulation GO:0030195 25 17 1,000 2,369E-03 0,02192031 ! RNA 3'-end processing GO:0031123 37 17 1,000 2,369E-03 0,0218376 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 2,411E-03 0,02213947 ! positive regulation of anti-apoptosis GO:0045768 47 18 1,000 2,657E-03 0,02431501 ! centrosome cycle GO:0007098 26 18 1,000 2,657E-03 0,02422428 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 2,657E-03 0,02413423 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 2,657E-03 0,02404484 ! nerve development GO:0021675 34 18 1,000 2,657E-03 0,02395612 ! defense response to virus GO:0051607 43 18 1,000 2,657E-03 0,02386804 ! sphingolipid metabolic process GO:0006665 122 65 2,000 2,758E-03 0,02468265 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 2,881E-03 0,02568361 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 2,881E-03 0,02559021 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 2,962E-03 0,02621587 ! peptide cross-linking GO:0018149 39 19 1,000 2,962E-03 0,02612122 ! peptide hormone secretion GO:0030072 32 19 1,000 2,962E-03 0,02602726 ! response to carbohydrate stimulus GO:0009743 33 20 1,000 3,282E-03 0,02873491 ! peptide secretion GO:0002790 38 20 1,000 3,282E-03 0,02863229 ! negative regulation of translation GO:0017148 32 20 1,000 3,282E-03 0,02853039 ! negative regulation of coagulation GO:0050819 30 20 1,000 3,282E-03 0,02842922 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 3,282E-03 0,02832877 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,282E-03 0,02822902 ! pancreas development GO:0031016 40 20 1,000 3,282E-03 0,02812997 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 3,282E-03 0,02803161 ! DNA duplex unwinding GO:0032508 30 20 1,000 3,282E-03 0,02793394 GO:0032392|DNA geometric change, ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 3,282E-03 0,02783695 ! cell cycle checkpoint GO:0000075 145 71 2,000 3,542E-03 0,02994502 ! aminoglycan metabolic process GO:0006022 121 71 2,000 3,542E-03 0,02984176 ! hormone secretion GO:0046879 39 21 1,000 3,617E-03 0,03036481 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 3,617E-03 0,03026082 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 3,617E-03 0,03015754 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 3,617E-03 0,03005496 ! leukotriene biosynthetic process GO:0019370 42 21 1,000 3,617E-03 0,02995308 GO:0043450|alkene biosynthetic process, ! actin filament organization GO:0007015 167 72 2,000 3,685E-03 0,03041336 ! membrane lipid metabolic process GO:0006643 132 72 2,000 3,685E-03 0,03031096 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,967E-03 0,0325255 ! cellular response to starvation GO:0009267 37 22 1,000 3,967E-03 0,03241672 ! cell aging GO:0007569 48 22 1,000 3,967E-03 0,03230867 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 3,967E-03 0,03220133 ! detection of chemical stimulus GO:0009593 42 22 1,000 3,967E-03 0,0320947 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,967E-03 0,03198878 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 3,967E-03 0,03188355 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,967E-03 0,03177902 ! regulation of caspase activity GO:0043281 136 74 2,000 3,98E-03 0,03177857 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 4,333E-03 0,0344822 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 4,333E-03 0,03437025 ! gluconeogenesis GO:0006094 38 23 1,000 4,333E-03 0,03425902 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,333E-03 0,0341485 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 1,000 4,333E-03 0,0340387 ! regulation of interleukin-6 production GO:0032675 31 23 1,000 4,333E-03 0,0339296 ! fatty acid transport GO:0015908 47 23 1,000 4,333E-03 0,0338212 ! hormone transport GO:0009914 41 23 1,000 4,333E-03 0,03371349 ! negative regulation of cytokine production GO:0001818 41 23 1,000 4,333E-03 0,03360647 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 4,333E-03 0,03350012 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 4,45E-03 0,03429489 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 4,714E-03 0,03621427 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 4,714E-03 0,03610075 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 4,714E-03 0,03598793 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 4,714E-03 0,03587582 ! leukotriene metabolic process GO:0006691 47 24 1,000 4,714E-03 0,03576441 ! blood coagulation GO:0007596 151 79 2,000 4,781E-03 0,03616073 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 2,000 4,781E-03 0,03604912 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 4,952E-03 0,03722272 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 5,11E-03 0,03829013 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 5,11E-03 0,03817303 ! negative regulation of DNA replication GO:0008156 45 25 1,000 5,11E-03 0,03805665 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 5,11E-03 0,03794098 ! lymphocyte proliferation GO:0046651 55 25 1,000 5,11E-03 0,03782601 ! positive regulation of protein secretion GO:0050714 41 25 1,000 5,11E-03 0,03771173 ! leukocyte homeostasis GO:0001776 50 25 1,000 5,11E-03 0,03759814 ! cellular alkene metabolic process GO:0043449 48 25 1,000 5,11E-03 0,03748523 ! regulation of peptidase activity GO:0052547 150 82 2,000 5,305E-03 0,03879968 ! cellular lipid catabolic process GO:0044242 150 83 2,000 5,486E-03 0,04001025 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 5,52E-03 0,04013405 ! pyruvate metabolic process GO:0006090 43 26 1,000 5,52E-03 0,04001496 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 5,52E-03 0,03989658 ! microtubule organizing center organization GO:0031023 42 26 1,000 5,52E-03 0,03977889 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 5,52E-03 0,03966189 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 5,52E-03 0,03954558 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 5,52E-03 0,03942995 ! response to metal ion GO:0010038 158 84 2,000 5,672E-03 0,04039893 ! hemostasis GO:0007599 165 85 2,000 5,861E-03 0,04162598 ! superoxide metabolic process GO:0006801 41 27 1,000 5,945E-03 0,04209623 ! response to starvation GO:0042594 47 27 1,000 5,945E-03 0,04197456 ! cellular response to nutrient levels GO:0031669 45 27 1,000 5,945E-03 0,0418536 ! leukocyte proliferation GO:0070661 59 27 1,000 5,945E-03 0,04173333 GO:0032943|mononuclear cell proliferation, ! positive regulation of cell activation GO:0050867 161 86 2,000 6,054E-03 0,04238108 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 2,000 6,251E-03 0,04363388 GO:0070201|regulation of establishment of protein localization, ! base-excision repair GO:0006284 41 28 1,000 6,384E-03 0,04443513 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 6,384E-03 0,04430889 ! lipid oxidation GO:0034440 48 28 1,000 6,384E-03 0,04418337 GO:0019395|fatty acid oxidation, ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 6,838E-03 0,04719017 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 6,838E-03 0,04705724 ! response to inorganic substance GO:0010035 173 90 2,000 6,865E-03 0,04710701 ! regulation of cell adhesion GO:0030155 241 92 2,000 7,293E-03 0,04990399 ! icosanoid biosynthetic process GO:0046456 60 30 1,000 7,306E-03 0,04985657 ! acute-phase response GO:0006953 50 30 1,000 7,306E-03 0,0497177 ! neurotransmitter secretion GO:0007269 55 30 1,000 7,306E-03 0,04957959 ! regulation of B cell activation GO:0050864 55 30 1,000 7,306E-03 0,04944225 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 7,512E-03 0,05069807 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 7,512E-03 0,05055841 ! regulation of membrane potential GO:0042391 179 94 2,000 7,736E-03 0,05192082 ! peptide transport GO:0015833 60 31 1,000 7,788E-03 0,05212717 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 7,788E-03 0,05198474 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 7,788E-03 0,0518431 ! response to heat GO:0009408 54 31 1,000 7,788E-03 0,05170222 ! ATP biosynthetic process GO:0006754 197 95 2,000 7,964E-03 0,05272408 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 8,284E-03 0,0546981 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 8,284E-03 0,05455067 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 8,284E-03 0,05440403 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 8,284E-03 0,05425817 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 8,284E-03 0,05411309 ! myeloid leukocyte activation GO:0002274 53 32 1,000 8,284E-03 0,05396879 ! regulation of protein localization GO:0032880 188 97 2,000 8,431E-03 0,05477645 ! leukocyte differentiation GO:0002521 232 98 2,000 8,67E-03 0,05618241 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 1,000 8,794E-03 0,05683595 ! negative regulation of secretion GO:0051048 68 35 1,000 9,855E-03 0,06352392 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 9,855E-03 0,06335676 ! regulation of muscle development GO:0048634 82 36 1,000 0,01040559 0,06672138 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01040559 0,06654672 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01096959 0,06997055 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,01096959 0,06978833 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01096959 0,06960706 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01096959 0,06942673 ! organic anion transport GO:0015711 82 38 1,000 0,01154682 0,07289117 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01154682 0,07270331 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01213714 0,07622375 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of hormone secretion GO:0046883 69 41 1,000 0,01335659 0,08366707 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01398548 0,08738243 ! T cell differentiation GO:0030217 93 42 1,000 0,01398548 0,08715951 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01398548 0,08693773 ! regulation of protein secretion GO:0050708 77 42 1,000 0,01398548 0,08671708 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01462699 0,09046513 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,01462699 0,09023668 ! glucose transport GO:0015758 66 43 1,000 0,01462699 0,09000939 ! monocarboxylic acid transport GO:0015718 93 43 1,000 0,01462699 0,08978323 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01462699 0,08955821 ! hexose transport GO:0008645 68 44 1,000 0,01528099 0,09332864 GO:0015749|monosaccharide transport, ! phagocytosis GO:0006909 105 44 1,000 0,01528099 0,0930959 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01594737 0,09691402 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01594737 0,09667354 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,01594737 0,09643425 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01594737 0,09619614 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01662603 0,10004281 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 0,01662603 0,099797 ! cell growth GO:0016049 90 46 1,000 0,01662603 0,0995524 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01801966 0,10763333 ! icosanoid metabolic process GO:0006690 92 48 1,000 0,01801966 0,10737081 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,01801966 0,10710957 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,01873442 0,11108782 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,01873442 0,11081884 ! endocrine system development GO:0035270 109 50 1,000 0,01946098 0,11483859 ! activation of caspase activity GO:0006919 95 50 1,000 0,01946098 0,11456187 ! regulation of ossification GO:0030278 123 50 1,000 0,01946098 0,11428648 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01946098 0,11401241 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,01946098 0,11373965 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02019924 0,11777265 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02019924 0,11749224 ! positive regulation of binding GO:0051099 88 52 1,000 0,02094908 0,12156437 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,02094908 0,1212763 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,02094908 0,1209896 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02120104 0,12215598 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02120104 0,12186855 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02120104 0,12158247 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02120104 0,12129774 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02120104 0,12101433 ! neuron fate determination GO:0048664 7 5 0,000 0,02120104 0,12073225 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02120104 0,12045147 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02120104 0,120172 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02120104 0,11989383 ! polyol transport GO:0015791 12 5 0,000 0,02120104 0,11961694 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02120104 0,11934132 ! response to superoxide GO:0000303 10 5 0,000 0,02120104 0,11906697 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02120104 0,11879388 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02120104 0,11852205 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02120104 0,11825145 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02120104 0,11798208 ! female meiosis GO:0007143 10 5 0,000 0,02120104 0,11771394 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02120104 0,11744702 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02120104 0,1171813 ! hypothalamus development GO:0021854 9 5 0,000 0,02120104 0,11691678 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02120104 0,11665345 ! cobalt ion transport GO:0006824 11 5 0,000 0,02120104 0,11639131 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02120104 0,11613034 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02120104 0,11587055 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02120104 0,11561191 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02120104 0,11535442 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02120104 0,11509808 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02120104 0,11484287 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02120104 0,11458879 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02120104 0,11433584 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! transposition GO:0032196 9 5 0,000 0,02120104 0,114084 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02120104 0,11383326 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02120104 0,11358363 ! negative chemotaxis GO:0050919 16 5 0,000 0,02120104 0,11333508 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02120104 0,11308763 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02120104 0,11284125 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02120104 0,11259594 ! behavioral response to pain GO:0048266 10 5 0,000 0,02120104 0,1123517 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02120104 0,11210851 ! Notch receptor processing GO:0007220 11 5 0,000 0,02120104 0,11186638 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02120104 0,11162529 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02120104 0,11138523 ! micturition GO:0060073 9 5 0,000 0,02120104 0,11114621 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02120104 0,11090821 ! copulation GO:0007620 9 5 0,000 0,02120104 0,11067123 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02120104 0,11043525 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02120104 0,11020028 ! bioluminescence GO:0008218 9 5 0,000 0,02120104 0,10996631 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02120104 0,10973333 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02120104 0,10950134 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02120104 0,10927032 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02120104 0,10904028 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02120104 0,10881121 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02120104 0,10858309 ! grooming behavior GO:0007625 6 5 0,000 0,02120104 0,10835593 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02120104 0,10812972 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02120104 0,10790445 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02120104 0,10768011 ! lymph vessel development GO:0001945 10 5 0,000 0,02120104 0,10745671 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02120104 0,10723423 ! endochondral ossification GO:0001958 17 5 0,000 0,02120104 0,10701267 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02120104 0,10679203 ! single strand break repair GO:0000012 8 5 0,000 0,02120104 0,10657229 ! parathyroid gland development GO:0060017 14 5 0,000 0,02120104 0,10635346 ! anagen GO:0042640 7 5 0,000 0,02120104 0,10613552 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02120104 0,10591847 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02120104 0,10570231 ! cytokine secretion GO:0050663 15 5 0,000 0,02120104 0,10548703 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02120104 0,10527263 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02120104 0,1050591 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02120104 0,10484642 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02120104 0,10463461 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02120104 0,10442366 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02120104 0,10421355 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02120104 0,10400428 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02120104 0,10379586 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02120104 0,10358827 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02120104 0,1033815 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02120104 0,10317557 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02120104 0,10297045 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02120104 0,10276614 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02120104 0,10256264 ! microvillus organization GO:0032528 8 5 0,000 0,02120104 0,10235995 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02120104 0,10215805 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02120104 0,10195696 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02120104 0,10175665 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02120104 0,10155713 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02120104 0,10135838 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02120104 0,10116042 ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02120104 0,10096322 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02120104 0,1007668 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02120104 0,10057113 ! muscle cell migration GO:0014812 8 5 0,000 0,02120104 0,10037623 ! mitochondrial fission GO:0000266 8 5 0,000 0,02120104 0,10018208 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02120104 0,09998868 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02120104 0,09979602 ! mRNA transcription GO:0009299 10 5 0,000 0,02120104 0,0996041 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02120104 0,09941292 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02120104 0,09922248 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02120104 0,09903276 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02120104 0,09884377 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02120104 0,09865549 ! monocyte activation GO:0042117 10 5 0,000 0,02120104 0,09846794 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02120104 0,09828109 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02120104 0,09809495 ! response to food GO:0032094 6 5 0,000 0,02120104 0,09790952 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02120104 0,09772478 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02120104 0,09754074 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02120104 0,09735739 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02120104 0,09717474 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02120104 0,09699276 ! forebrain neuron development GO:0021884 13 5 0,000 0,02120104 0,09681147 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02120104 0,09663085 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02120104 0,0964509 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02120104 0,09627162 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02120104 0,09609301 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02120104 0,09591506 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02120104 0,09573777 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02120104 0,09556113 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02120104 0,09538515 ! lipid glycosylation GO:0030259 7 5 0,000 0,02120104 0,0952098 ! nucleobase transport GO:0015851 6 5 0,000 0,02120104 0,09503511 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02120104 0,09486105 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02120104 0,09468763 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02120104 0,09451484 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02120104 0,09434268 ! basic amino acid transport GO:0015802 12 5 0,000 0,02120104 0,09417115 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02120104 0,09400024 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02120104 0,09382995 ! actin nucleation GO:0045010 11 5 0,000 0,02120104 0,09366028 ! depurination GO:0045007 5 5 0,000 0,02120104 0,09349122 ! depyrimidination GO:0045008 10 5 0,000 0,02120104 0,09332276 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02120104 0,09315492 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02120104 0,09298767 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02120104 0,09282103 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02120104 0,09265498 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02120104 0,09248952 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02120104 0,09232466 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02120104 0,09216038 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02120104 0,09199669 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02120104 0,09183357 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02120104 0,09167103 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02120104 0,09150907 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02120104 0,09134768 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02120104 0,09118686 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02120104 0,0910266 ! response to arsenic GO:0046685 11 5 0,000 0,02120104 0,0908669 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02120104 0,09070777 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02120104 0,09054919 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02120104 0,09039116 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02120104 0,09023368 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02120104 0,09007675 ! response to mercury ion GO:0046689 8 5 0,000 0,02120104 0,08992037 ! response to cadmium ion GO:0046686 7 5 0,000 0,02120104 0,08976453 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02120104 0,08960923 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02120104 0,08945446 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02120104 0,08930023 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02120104 0,08914653 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02120104 0,08899336 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02120104 0,08884071 ! decidualization GO:0046697 11 5 0,000 0,02120104 0,08868859 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02120104 0,08853698 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02120104 0,08838589 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02120104 0,08823532 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02120104 0,08808526 ! embryonic cleavage GO:0040016 6 5 0,000 0,02120104 0,08793571 ! peroxisome fission GO:0016559 5 5 0,000 0,02120104 0,08778667 ! histone demethylation GO:0016577 13 5 0,000 0,02120104 0,08763813 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02120104 0,08749009 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02120104 0,08734255 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02120104 0,08719551 ! metaphase plate congression GO:0051310 7 5 0,000 0,02120104 0,08704896 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02120104 0,08690291 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02120104 0,08675734 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02120104 0,08661226 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02120104 0,08646767 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02120104 0,08632356 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02120104 0,08617992 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02120104 0,08603677 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02120104 0,08589409 ! B cell homeostasis GO:0001782 13 5 0,000 0,02120104 0,08575188 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02120104 0,08561014 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02120104 0,08546887 ! metaphase GO:0051323 11 5 0,000 0,02120104 0,08532806 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02120104 0,08518772 GO:0030186|melatonin metabolic process, ! cellular response to nutrient GO:0031670 8 5 0,000 0,02120104 0,08504784 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02120104 0,08490842 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02120104 0,08476945 ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02120104 0,08463094 ! response to redox state GO:0051775 6 5 0,000 0,02120104 0,08449288 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02120104 0,08435527 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02120104 0,0842181 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02120104 0,08408139 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02120104 0,08394511 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02120104 0,08380928 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02120104 0,08367388 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02120104 0,08353893 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02120104 0,0834044 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02120104 0,08327031 ! striatum development GO:0021756 14 5 0,000 0,02120104 0,08313665 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02120104 0,08300342 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02120104 0,08287061 ! glial cell migration GO:0008347 10 5 0,000 0,02120104 0,08273823 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02120104 0,08260627 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02120104 0,08247474 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02120104 0,08234362 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02120104 0,08221291 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02120104 0,08208262 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02120104 0,08195274 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02120104 0,08182328 ! neuroprotection GO:0043526 8 5 0,000 0,02120104 0,08169422 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02120104 0,08156557 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02120104 0,08143732 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02120104 0,08130947 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02120104 0,08118203 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02120104 0,08105498 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02120104 0,08092833 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02120104 0,08080208 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02120104 0,08067622 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02120104 0,08055075 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02120104 0,08042567 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02120104 0,08030098 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02120104 0,08017668 ! spindle assembly GO:0051225 6 5 0,000 0,02120104 0,08005276 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02120104 0,07992922 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02120104 0,07980606 ! protein palmitoylation GO:0018345 12 5 0,000 0,02120104 0,07968328 ! drug metabolic process GO:0017144 7 5 0,000 0,02120104 0,07956088 ! stem cell division GO:0017145 11 5 0,000 0,02120104 0,07943886 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02120104 0,0793172 ! organ regeneration GO:0031100 7 5 0,000 0,02120104 0,07919592 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02120104 0,07907501 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02120104 0,07895447 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,02171039 0,08072829 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to UV GO:0009411 120 55 1,000 0,02326699 0,08638488 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02406206 0,08920122 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,02486816 0,09204986 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02486816 0,0919106 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,02486816 0,09177176 GO:0010952|positive regulation of peptidase activity, ! regulation of intracellular transport GO:0032386 108 57 1,000 0,02486816 0,09163335 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02538735 0,09340557 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02538735 0,09326511 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02538735 0,09312508 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02538735 0,09298546 GO:0030816|positive regulation of cAMP metabolic process, ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02538735 0,09284626 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02538735 0,09270748 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02538735 0,09256911 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02538735 0,09243115 ! response to oxygen radical GO:0000305 11 6 0,000 0,02538735 0,0922936 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02538735 0,09215647 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02538735 0,09201973 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02538735 0,09188341 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02538735 0,09174749 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02538735 0,09161197 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02538735 0,09147685 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02538735 0,09134212 ! forebrain regionalization GO:0021871 9 6 0,000 0,02538735 0,0912078 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02538735 0,09107386 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02538735 0,09094032 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02538735 0,09080718 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02538735 0,09067442 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02538735 0,09054205 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02538735 0,09041006 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02538735 0,09027846 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02538735 0,09014724 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02538735 0,0900164 ! malate metabolic process GO:0006108 13 6 0,000 0,02538735 0,08988594 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02538735 0,08975586 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02538735 0,08962616 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02538735 0,08949683 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02538735 0,08936787 ! protein refolding GO:0042026 15 6 0,000 0,02538735 0,08923928 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02538735 0,08911106 ! opsonization GO:0008228 8 6 0,000 0,02538735 0,08898322 ! mating behavior GO:0007617 7 6 0,000 0,02538735 0,08885573 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02538735 0,08872861 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02538735 0,08860186 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02538735 0,08847546 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02538735 0,08834943 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02538735 0,08822376 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02538735 0,08809844 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02538735 0,08797348 ! toxin metabolic process GO:0009404 11 6 0,000 0,02538735 0,08784887 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02538735 0,08772461 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02538735 0,08760071 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02538735 0,08747715 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02538735 0,08735394 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02538735 0,08723108 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02538735 0,08710857 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02538735 0,0869864 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02538735 0,08686457 ! thymic T cell selection GO:0045061 16 6 0,000 0,02538735 0,08674308 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02538735 0,08662193 ! protein lipoylation GO:0009249 10 6 0,000 0,02538735 0,08650112 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02538735 0,08638064 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02538735 0,0862605 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02538735 0,0861407 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02538735 0,08602122 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02538735 0,08590208 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02538735 0,08578327 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02538735 0,08566478 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! response to pH GO:0009268 10 6 0,000 0,02538735 0,08554662 ! hyperosmotic response GO:0006972 10 6 0,000 0,02538735 0,08542879 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02538735 0,08531128 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02538735 0,08519409 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02538735 0,08507723 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02538735 0,08496069 ! urea metabolic process GO:0019627 7 6 0,000 0,02538735 0,08484446 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02538735 0,08472855 ! neutrophil activation GO:0042119 7 6 0,000 0,02538735 0,08461296 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02538735 0,08449769 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02538735 0,08438272 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02538735 0,08426807 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02538735 0,08415373 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02538735 0,0840397 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02538735 0,08392598 ! neuron apoptosis GO:0051402 15 6 0,000 0,02538735 0,08381257 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02538735 0,08369946 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02538735 0,08358666 ! folic acid transport GO:0015884 14 6 0,000 0,02538735 0,08347416 ! carnitine transport GO:0015879 10 6 0,000 0,02538735 0,08336196 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02538735 0,08325007 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02538735 0,08313847 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02538735 0,08302718 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02538735 0,08291618 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02538735 0,08280548 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02538735 0,08269507 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02538735 0,08258495 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02538735 0,08247513 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02538735 0,08236561 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02538735 0,08225637 ! astrocyte development GO:0014002 16 6 0,000 0,02538735 0,08214742 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02538735 0,08203876 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02538735 0,08193038 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02538735 0,0818223 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02538735 0,08171449 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02538735 0,08160697 ! response to copper ion GO:0046688 10 6 0,000 0,02538735 0,08149974 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02538735 0,08139278 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02538735 0,08128611 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02538735 0,08117971 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02538735 0,0810736 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02538735 0,08096776 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02538735 0,08086219 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02538735 0,0807569 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02538735 0,08065189 ! hair follicle maturation GO:0048820 8 6 0,000 0,02538735 0,08054714 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02538735 0,08044267 ! Schwann cell development GO:0014044 15 6 0,000 0,02538735 0,08033847 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02538735 0,08023454 ! response to pheromone GO:0019236 6 6 0,000 0,02538735 0,08013088 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02538735 0,08002749 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02538735 0,07992436 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02538735 0,07982149 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02538735 0,0797189 ! subpallium development GO:0021544 15 6 0,000 0,02538735 0,07961656 ! neural tube patterning GO:0021532 8 6 0,000 0,02538735 0,07951449 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02538735 0,07941268 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02538735 0,07931113 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02538735 0,07920984 ! G2 phase GO:0051319 16 6 0,000 0,02538735 0,0791088 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02538735 0,07900803 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02538735 0,07890751 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02538735 0,07880724 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02538735 0,07870723 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02538735 0,07860748 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02538735 0,07850798 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02538735 0,07840872 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02538735 0,07830972 ! receptor internalization GO:0031623 11 6 0,000 0,02538735 0,07821097 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02538735 0,07811247 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02538735 0,07801422 ! protein deubiquitination GO:0016579 16 6 0,000 0,02538735 0,07791621 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02538735 0,07781845 ! protein destabilization GO:0031648 9 6 0,000 0,02538735 0,07772093 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02538735 0,07762366 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02538735 0,07752663 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02538735 0,07742984 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02538735 0,07733329 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02538735 0,07723699 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02538735 0,07714092 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02538735 0,07704509 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02538735 0,0769495 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02538735 0,07685415 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02538735 0,07675904 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02538735 0,07666415 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02538735 0,07656951 ! neural plate development GO:0001840 9 6 0,000 0,02538735 0,07647509 ! catecholamine transport GO:0051937 9 6 0,000 0,02538735 0,07638091 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02538735 0,07628696 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02538735 0,07619324 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02538735 0,07609976 ! maternal placenta development GO:0001893 12 6 0,000 0,02538735 0,0760065 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02538735 0,07591347 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02538735 0,07582066 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02538735 0,07572808 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02538735 0,07563573 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02538735 0,07554361 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02538735 0,0754517 GO:0055081|anion homeostasis, ! aging GO:0007568 112 58 1,000 0,02568518 0,07624412 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,02568518 0,07615159 ! maintenance of location GO:0051235 124 58 1,000 0,02568518 0,07605928 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,02735159 0,08089581 ! lipid modification GO:0030258 112 60 1,000 0,02735159 0,08079799 ! positive regulation of secretion GO:0051047 110 61 1,000 0,02820076 0,08320587 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,02820076 0,0831055 ! viral reproductive process GO:0022415 132 62 1,000 0,02906043 0,08553571 ! tRNA transcription GO:0009304 17 7 0,000 0,02955588 0,08688931 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02955588 0,08678487 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02955588 0,08668069 ! regulation of helicase activity GO:0051095 16 7 0,000 0,02955588 0,08657675 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02955588 0,08647307 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02955588 0,08636963 ! sleep GO:0030431 16 7 0,000 0,02955588 0,08626644 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02955588 0,0861635 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02955588 0,0860608 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02955588 0,08595835 ! prostate gland development GO:0030850 14 7 0,000 0,02955588 0,08585614 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02955588 0,08575417 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02955588 0,08565245 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02955588 0,08555096 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02955588 0,08544972 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02955588 0,08534872 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02955588 0,08524795 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02955588 0,08514742 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02955588 0,08504713 ! glycolipid transport GO:0046836 11 7 0,000 0,02955588 0,08494707 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02955588 0,08484725 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02955588 0,08474767 ! neuron adhesion GO:0007158 14 7 0,000 0,02955588 0,08464832 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,02955588 0,0845492 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02955588 0,08445031 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02955588 0,08435165 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02955588 0,08425322 ! mRNA stabilization GO:0048255 18 7 0,000 0,02955588 0,08415503 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02955588 0,08405706 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02955588 0,08395932 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02955588 0,0838618 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02955588 0,08376452 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02955588 0,08366745 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02955588 0,08357062 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02955588 0,083474 ! lipoprotein transport GO:0042953 14 7 0,000 0,02955588 0,08337761 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02955588 0,08328145 ! rhythmic behavior GO:0007622 17 7 0,000 0,02955588 0,0831855 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02955588 0,08308977 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02955588 0,08299427 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02955588 0,08289898 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02955588 0,08280391 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02955588 0,08270906 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02955588 0,08261443 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02955588 0,08252001 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02955588 0,08242581 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02955588 0,08233183 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02955588 0,08223806 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02955588 0,0821445 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02955588 0,08205115 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02955588 0,08195802 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02955588 0,08186509 ! spinal cord patterning GO:0021511 14 7 0,000 0,02955588 0,08177238 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02955588 0,08167988 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02955588 0,08158759 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02955588 0,0814955 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02955588 0,08140362 ! adrenal gland development GO:0030325 17 7 0,000 0,02955588 0,08131195 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02955588 0,08122049 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02955588 0,08112923 ! ovulation GO:0030728 10 7 0,000 0,02955588 0,08103817 ! adenohypophysis development GO:0021984 11 7 0,000 0,02955588 0,08094732 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02955588 0,08085668 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02955588 0,08076623 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 21 7 0,000 0,02955588 0,08067599 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02955588 0,08058595 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02955588 0,08049611 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02955588 0,08040647 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02955588 0,08031703 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02955588 0,08022779 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02955588 0,08013875 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02955588 0,0800499 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02955588 0,07996125 ! galactose metabolic process GO:0006012 13 7 0,000 0,02955588 0,0798728 ! vesicle fusion GO:0006906 20 7 0,000 0,02955588 0,07978454 ! response to dietary excess GO:0002021 8 7 0,000 0,02955588 0,07969648 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02955588 0,07960861 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02955588 0,07952094 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02955588 0,07943346 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02955588 0,07934617 ! organ growth GO:0035265 15 7 0,000 0,02955588 0,07925907 ! nucleoside transport GO:0015858 11 7 0,000 0,02955588 0,07917216 ! nucleoside salvage GO:0043174 11 7 0,000 0,02955588 0,07908545 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02955588 0,07899892 ! male sex determination GO:0030238 15 7 0,000 0,02955588 0,07891258 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02955588 0,07882643 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02955588 0,07874047 ! parturition GO:0007567 16 7 0,000 0,02955588 0,0786547 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02955588 0,07856911 ! rRNA modification GO:0000154 14 7 0,000 0,02955588 0,07848371 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02955588 0,07839849 ! spindle checkpoint GO:0031577 16 7 0,000 0,02955588 0,07831346 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02955588 0,07822862 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02955588 0,07814395 ! monocyte differentiation GO:0030224 16 7 0,000 0,02955588 0,07805947 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02955588 0,07797518 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02955588 0,07789106 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02955588 0,07780713 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02955588 0,07772337 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,02955588 0,0776398 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02955588 0,07755641 ! fibrinolysis GO:0042730 11 7 0,000 0,02955588 0,07747319 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02955588 0,07739015 ! eating behavior GO:0042755 8 7 0,000 0,02955588 0,07730729 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02955588 0,07722461 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02955588 0,07714211 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02955588 0,07705978 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02955588 0,07697763 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02955588 0,07689565 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02955588 0,07681384 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02955588 0,07673221 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02955588 0,07665076 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02955588 0,07656947 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02955588 0,07648836 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02955588 0,07640742 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02955588 0,07632665 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02955588 0,07624605 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02955588 0,07616563 ! histone ubiquitination GO:0016574 9 7 0,000 0,02955588 0,07608537 ! regulation of meiosis GO:0040020 12 7 0,000 0,02955588 0,07600528 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02955588 0,07592536 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02955588 0,0758456 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02955588 0,07576602 GO:0002714|positive regulation of B cell mediated immunity, ! membrane to membrane docking GO:0022614 14 7 0,000 0,02955588 0,0756866 ! transcription termination GO:0006353 14 7 0,000 0,02955588 0,07560734 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02955588 0,07552826 ! anaphase GO:0051322 18 7 0,000 0,02955588 0,07544933 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02955588 0,07537058 ! axonal fasciculation GO:0007413 19 7 0,000 0,02955588 0,07529198 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02955588 0,07521356 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02955588 0,07513529 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02955588 0,07505719 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02955588 0,07497925 ! diuresis GO:0030146 12 7 0,000 0,02955588 0,07490147 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02955588 0,07482385 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02955588 0,07474639 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02955588 0,07466909 ! antibiotic transport GO:0042891 9 7 0,000 0,02955588 0,07459196 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02955588 0,07451498 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02955588 0,07443816 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02955588 0,0743615 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02955588 0,07428499 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02955588 0,07420865 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02955588 0,07413246 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02955588 0,07405642 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02955588 0,07398055 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02955588 0,07390482 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02955588 0,07382926 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02955588 0,07375384 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02955588 0,07367858 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02955588 0,07360348 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02955588 0,07352853 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02955588 0,07345373 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02955588 0,07337908 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02955588 0,07330458 ! muscle adaptation GO:0043500 13 7 0,000 0,02955588 0,07323024 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02955588 0,07315604 ! retina homeostasis GO:0001895 12 7 0,000 0,02955588 0,073082 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02955588 0,0730081 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02955588 0,07293436 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02955588 0,07286076 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,03170143 0,07807117 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,03260208 0,08020835 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,03351272 0,08236578 ! activation of MAPK activity GO:0000187 124 67 1,000 0,03351272 0,082283 ! chromosome segregation GO:0007059 127 67 1,000 0,03351272 0,08220038 ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,03351272 0,08211794 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,03351272 0,08203565 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03370669 0,08242788 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03370669 0,08234545 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,03370669 0,08226319 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03370669 0,08218109 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03370669 0,08209916 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03370669 0,08201738 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03370669 0,08193577 ! male meiosis GO:0007140 9 8 0,000 0,03370669 0,08185433 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03370669 0,08177304 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03370669 0,08169192 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03370669 0,08161096 ! meiotic prophase I GO:0007128 14 8 0,000 0,03370669 0,08153015 ! response to zinc ion GO:0010043 12 8 0,000 0,03370669 0,08144951 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03370669 0,08136903 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03370669 0,0812887 ! oligopeptide transport GO:0006857 16 8 0,000 0,03370669 0,08120853 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03370669 0,08112853 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03370669 0,08104867 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03370669 0,08096898 ! signal peptide processing GO:0006465 12 8 0,000 0,03370669 0,08088944 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03370669 0,08081006 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03370669 0,08073084 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03370669 0,08065177 ! succinate metabolic process GO:0006105 17 8 0,000 0,03370669 0,08057285 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03370669 0,08049409 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03370669 0,08041548 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03370669 0,08033703 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03370669 0,08025873 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03370669 0,08018058 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03370669 0,08010258 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03370669 0,08002474 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03370669 0,07994704 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03370669 0,0798695 ! reflex GO:0060004 17 8 0,000 0,03370669 0,07979211 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03370669 0,07971486 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03370669 0,07963777 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03370669 0,07956082 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03370669 0,07948403 ! pigment granule organization GO:0048753 17 8 0,000 0,03370669 0,07940738 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03370669 0,07933088 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03370669 0,07925453 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03370669 0,07917832 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03370669 0,07910226 ! histidine catabolic process GO:0006548 10 8 0,000 0,03370669 0,07902635 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03370669 0,07895058 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03370669 0,07887496 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03370669 0,07879948 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,03370669 0,07872414 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03370669 0,07864895 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03370669 0,07857391 ! melanin metabolic process GO:0006582 17 8 0,000 0,03370669 0,078499 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03370669 0,07842424 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03370669 0,07834962 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03370669 0,07827515 ! macrophage activation GO:0042116 13 8 0,000 0,03370669 0,07820081 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03370669 0,07812662 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03370669 0,07805256 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03370669 0,07797865 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03370669 0,07790488 ! purine salvage GO:0043101 12 8 0,000 0,03370669 0,07783124 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03370669 0,07775775 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03370669 0,07768439 ! osteoblast development GO:0002076 17 8 0,000 0,03370669 0,07761117 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03370669 0,07753809 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03370669 0,07746515 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03370669 0,07739234 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03370669 0,07731967 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03370669 0,07724714 ! response to UV-B GO:0010224 17 8 0,000 0,03370669 0,07717475 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03370669 0,07710248 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03370669 0,07703036 ! intermediate filament organization GO:0045109 12 8 0,000 0,03370669 0,07695837 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03370669 0,07688651 ! cellular extravasation GO:0045123 13 8 0,000 0,03370669 0,07681479 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03370669 0,0767432 ! response to antibiotic GO:0046677 11 8 0,000 0,03370669 0,07667174 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03370669 0,07660042 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03370669 0,07652923 ! DNA topological change GO:0006265 12 8 0,000 0,03370669 0,07645817 ! response to tropane GO:0014073 15 8 0,000 0,03370669 0,07638725 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,03370669 0,07631645 ! melanosome transport GO:0032402 13 8 0,000 0,03370669 0,07624579 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,03370669 0,07617526 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03370669 0,07610486 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03370669 0,07603458 ! mast cell activation GO:0045576 14 8 0,000 0,03370669 0,07596444 ! gas homeostasis GO:0033483 14 8 0,000 0,03370669 0,07589443 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03370669 0,07582454 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03370669 0,07575479 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03370669 0,07568516 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03370669 0,07561566 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03370669 0,07554629 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03370669 0,07547704 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03370669 0,07540792 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03370669 0,07533893 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03370669 0,07527007 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03370669 0,07520133 ! response to tumor cell GO:0002347 16 8 0,000 0,03370669 0,07513271 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03370669 0,07506422 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03370669 0,07499586 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03370669 0,07492762 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03370669 0,0748595 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03370669 0,07479151 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03370669 0,07472364 ! hormone catabolic process GO:0042447 17 8 0,000 0,03370669 0,0746559 ! lymph node development GO:0048535 11 8 0,000 0,03370669 0,07458827 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03370669 0,07452077 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03370669 0,07445339 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03370669 0,07438614 GO:0010828|positive regulation of glucose transport, ! adult feeding behavior GO:0008343 10 8 0,000 0,03370669 0,074319 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03370669 0,07425199 ! ATP catabolic process GO:0006200 11 8 0,000 0,03370669 0,07418509 ! blastocyst growth GO:0001832 19 8 0,000 0,03370669 0,07411832 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03370669 0,07405167 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03370669 0,07398513 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03370669 0,07391872 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03370669 0,07385242 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03370669 0,07378625 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03370669 0,07372019 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03370669 0,07365425 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03370669 0,07358843 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03370669 0,07352273 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03370669 0,07345714 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03370669 0,07339167 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03370669 0,07332632 ! protein prenylation GO:0018342 21 8 0,000 0,03370669 0,07326108 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03370669 0,07319596 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03370669 0,07313095 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03370669 0,07306606 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03370669 0,07300129 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,03443325 0,0745088 ! extracellular matrix organization GO:0030198 146 68 1,000 0,03443325 0,07444286 ! detection of external stimulus GO:0009581 102 68 1,000 0,03443325 0,07437704 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,03443325 0,07431134 ! viral reproduction GO:0016032 142 68 1,000 0,03443325 0,07424575 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,03443325 0,07418028 ! cell projection assembly GO:0030031 138 68 1,000 0,03443325 0,07411492 ! negative regulation of cell size GO:0045792 144 69 1,000 0,03536357 0,07605036 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,03536357 0,07598347 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,03536357 0,0759167 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,03725318 0,079903 ! axon extension GO:0048675 16 9 0,000 0,03783987 0,08109018 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03783987 0,08101911 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03783987 0,08094817 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03783987 0,08087735 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03783987 0,08080665 GO:0006740|NADPH regeneration, ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03783987 0,08073607 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03783987 0,08066562 ! reproductive behavior GO:0019098 22 9 0,000 0,03783987 0,0805953 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03783987 0,08052509 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03783987 0,08045501 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03783987 0,08038505 ! UTP metabolic process GO:0046051 10 9 0,000 0,03783987 0,08031521 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03783987 0,08024549 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03783987 0,08017589 ! artery development GO:0060840 25 9 0,000 0,03783987 0,08010642 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03783987 0,08003706 ! regulation of glycolysis GO:0006110 20 9 0,000 0,03783987 0,07996782 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03783987 0,07989871 ! equilibrioception GO:0050957 20 9 0,000 0,03783987 0,07982971 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03783987 0,07976083 ! chemosensory behavior GO:0007635 21 9 0,000 0,03783987 0,07969207 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03783987 0,07962343 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03783987 0,07955491 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03783987 0,07948651 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03783987 0,07941822 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03783987 0,07935005 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03783987 0,07928199 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03783987 0,07921406 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03783987 0,07914624 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03783987 0,07907853 ! protein targeting to ER GO:0045047 25 9 0,000 0,03783987 0,07901094 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03783987 0,07894347 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03783987 0,07887611 ! T cell selection GO:0045058 27 9 0,000 0,03783987 0,07880887 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,03783987 0,07874174 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03783987 0,07867473 ! glycine catabolic process GO:0006546 15 9 0,000 0,03783987 0,07860783 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03783987 0,07854104 ! endosome organization GO:0007032 20 9 0,000 0,03783987 0,07847437 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03783987 0,07840781 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03783987 0,07834136 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03783987 0,07827503 ! mannose metabolic process GO:0006013 13 9 0,000 0,03783987 0,0782088 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03783987 0,07814269 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03783987 0,07807669 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03783987 0,07801081 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03783987 0,07794503 ! receptor clustering GO:0043113 20 9 0,000 0,03783987 0,07787936 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03783987 0,07781381 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03783987 0,07774836 ! retinol metabolic process GO:0042572 20 9 0,000 0,03783987 0,07768303 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03783987 0,0776178 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03783987 0,07755269 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03783987 0,07748768 ! macrophage differentiation GO:0030225 15 9 0,000 0,03783987 0,07742279 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03783987 0,077358 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03783987 0,07729332 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03783987 0,07722874 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03783987 0,07716428 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03783987 0,07709992 ! response to amine stimulus GO:0014075 13 9 0,000 0,03783987 0,07703567 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03783987 0,07697153 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03783987 0,07690749 ! erythrocyte development GO:0048821 17 9 0,000 0,03783987 0,07684356 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03783987 0,07677974 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03783987 0,07671602 ! renal water homeostasis GO:0003091 15 9 0,000 0,03783987 0,07665241 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03783987 0,0765889 ! icosanoid secretion GO:0032309 15 9 0,000 0,03783987 0,0765255 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03783987 0,0764622 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03783987 0,07639901 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03783987 0,07633593 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03783987 0,07627294 ! sterol catabolic process GO:0016127 14 9 0,000 0,03783987 0,07621006 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03783987 0,07614729 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03783987 0,07608461 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03783987 0,07602204 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03783987 0,07595958 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03783987 0,07589721 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03783987 0,07583495 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03783987 0,07577279 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03783987 0,07571073 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03783987 0,07564878 ! purine base metabolic process GO:0006144 25 9 0,000 0,03783987 0,07558692 ! pigment granule transport GO:0051904 17 9 0,000 0,03783987 0,07552517 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03783987 0,07546351 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03783987 0,07540196 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03783987 0,07534051 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03783987 0,07527916 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03783987 0,07521791 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03783987 0,07515675 ! carbohydrate transport GO:0008643 114 72 1,000 0,03821227 0,07583475 ! B cell activation GO:0042113 179 72 1,000 0,03821227 0,0757732 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,03821227 0,07571174 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,03821227 0,07565039 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,03821227 0,07558913 ! humoral immune response GO:0006959 115 73 1,000 0,03918076 0,07744223 ! regulation of immune effector process GO:0002697 156 73 1,000 0,03918076 0,07737962 ! acute inflammatory response GO:0002526 118 74 1,000 0,04015854 0,07924663 ! amino acid transport GO:0006865 148 74 1,000 0,04015854 0,07918267 ! organelle localization GO:0051640 155 74 1,000 0,04015854 0,07911881 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,04114553 0,08099802 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,04114553 0,0809328 ! axon guidance GO:0007411 162 75 1,000 0,04114553 0,08086769 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04195549 0,08239329 ! regulation of developmental growth GO:0048638 16 10 0,000 0,04195549 0,08232711 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,04195549 0,08226104 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04195549 0,08219507 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04195549 0,08212921 ! associative learning GO:0008306 21 10 0,000 0,04195549 0,08206345 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04195549 0,0819978 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04195549 0,08193225 ! phosphate transport GO:0006817 24 10 0,000 0,04195549 0,08186681 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04195549 0,08180148 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04195549 0,08173624 ! CTP metabolic process GO:0046036 11 10 0,000 0,04195549 0,08167112 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04195549 0,08160609 ! GTP metabolic process GO:0046039 11 10 0,000 0,04195549 0,08154117 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04195549 0,08147635 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04195549 0,08141164 ! social behavior GO:0035176 29 10 0,000 0,04195549 0,08134702 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04195549 0,08128251 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04195549 0,08121811 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04195549 0,0811538 ! androgen metabolic process GO:0008209 17 10 0,000 0,04195549 0,0810896 ! phospholipid efflux GO:0033700 19 10 0,000 0,04195549 0,08102549 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04195549 0,08096149 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04195549 0,08089759 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04195549 0,08083379 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04195549 0,08077009 ! lung alveolus development GO:0048286 26 10 0,000 0,04195549 0,0807065 ! pathogenesis GO:0009405 17 10 0,000 0,04195549 0,080643 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04195549 0,0805796 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04195549 0,0805163 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04195549 0,0804531 ! endoderm development GO:0007492 18 10 0,000 0,04195549 0,08039 ! arginine catabolic process GO:0006527 17 10 0,000 0,04195549 0,080327 ! proline metabolic process GO:0006560 13 10 0,000 0,04195549 0,0802641 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04195549 0,08020129 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04195549 0,08013858 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04195549 0,08007598 ! V(D)J recombination GO:0033151 34 10 0,000 0,04195549 0,08001347 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04195549 0,07995105 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04195549 0,07988874 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04195549 0,07982652 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04195549 0,0797644 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04195549 0,07970237 ! multicellular organism growth GO:0035264 19 10 0,000 0,04195549 0,07964044 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04195549 0,07957861 ! ruffle organization GO:0031529 17 10 0,000 0,04195549 0,07951687 ! epithelial cell development GO:0002064 21 10 0,000 0,04195549 0,07945523 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04195549 0,07939369 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04195549 0,07933224 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04195549 0,07927088 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04195549 0,07920962 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04195549 0,07914846 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04195549 0,07908738 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04195549 0,07902641 ! motor axon guidance GO:0008045 22 10 0,000 0,04195549 0,07896552 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04195549 0,07890473 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04195549 0,07884404 ! protein heterooligomerization GO:0051291 17 10 0,000 0,04195549 0,07878344 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04195549 0,07872293 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04195549 0,07866251 ! segment specification GO:0007379 15 10 0,000 0,04195549 0,07860219 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04195549 0,07854195 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04195549 0,07848181 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04195549 0,07842177 ! response to dsRNA GO:0043331 23 10 0,000 0,04195549 0,07836181 ! DNA ligation GO:0006266 18 10 0,000 0,04195549 0,07830195 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04195549 0,07824218 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04195549 0,07818249 ! melanosome localization GO:0032400 16 10 0,000 0,04195549 0,0781229 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04195549 0,0780634 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04195549 0,078004 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04195549 0,07794468 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04195549 0,07788545 ! induction of an organ GO:0001759 17 10 0,000 0,04195549 0,07782631 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04195549 0,07776726 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04195549 0,0777083 ! protein sumoylation GO:0016925 17 10 0,000 0,04195549 0,07764943 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04195549 0,07759065 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04195549 0,07753196 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04195549 0,07747336 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04195549 0,07741484 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04195549 0,07735642 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 14 10 0,000 0,04195549 0,07729808 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04195549 0,07723983 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04195549 0,07718166 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04195549 0,07712359 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04195549 0,0770656 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04195549 0,0770077 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04195549 0,07694989 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04195549 0,07689216 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04195549 0,07683452 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04195549 0,07677697 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,04195549 0,0767195 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04195549 0,07666212 ! blastocyst formation GO:0001825 18 10 0,000 0,04195549 0,07660482 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04195549 0,07654761 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04195549 0,07649049 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04195549 0,07643345 ! response to nicotine GO:0035094 20 10 0,000 0,04195549 0,07637649 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04195549 0,07631962 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04195549 0,07626283 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,04214163 0,07654424 ! neurotransmitter transport GO:0006836 142 77 1,000 0,04314674 0,07831165 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,04314674 0,07825351 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,04314674 0,07819546 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,04416077 0,07997387 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,04518362 0,08176561 ! respiratory burst GO:0045730 17 11 0,000 0,04605361 0,08327829 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04605361 0,08321669 ! neuron fate specification GO:0048665 18 11 0,000 0,04605361 0,08315519 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04605361 0,08309377 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04605361 0,08303245 ! thyroid gland development GO:0030878 26 11 0,000 0,04605361 0,08297122 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,04605361 0,08291007 ! synapsis GO:0007129 14 11 0,000 0,04605361 0,08284902 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04605361 0,08278806 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04605361 0,08272718 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,04605361 0,0826664 ! response to pain GO:0048265 27 11 0,000 0,04605361 0,0826057 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04605361 0,0825451 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04605361 0,08248458 ! bone resorption GO:0045453 16 11 0,000 0,04605361 0,08242415 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04605361 0,08236381 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,04605361 0,08230356 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04605361 0,0822434 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04605361 0,08218332 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04605361 0,08212334 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04605361 0,08206343 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04605361 0,08200362 ! L-serine metabolic process GO:0006563 21 11 0,000 0,04605361 0,0819439 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,04605361 0,08188426 ! UV protection GO:0009650 20 11 0,000 0,04605361 0,0818247 ! adult heart development GO:0007512 16 11 0,000 0,04605361 0,08176524 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04605361 0,08170586 ! macroautophagy GO:0016236 19 11 0,000 0,04605361 0,08164657 ! temperature homeostasis GO:0001659 18 11 0,000 0,04605361 0,08158736 ! behavioral fear response GO:0001662 27 11 0,000 0,04605361 0,08152824 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04605361 0,0814692 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04605361 0,08141025 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04605361 0,08135139 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04605361 0,08129261 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04605361 0,08123391 ! regulation of organ growth GO:0046620 14 11 0,000 0,04605361 0,0811753 ! pigment granule localization GO:0051875 20 11 0,000 0,04605361 0,08111678 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04605361 0,08105834 ! vasoconstriction GO:0042310 20 11 0,000 0,04605361 0,08099998 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04605361 0,0809417 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04605361 0,08088351 ! embryonic axis specification GO:0000578 19 11 0,000 0,04605361 0,08082541 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04605361 0,08076739 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04605361 0,08070945 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04605361 0,08065159 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04605361 0,08059382 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04605361 0,08053613 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04605361 0,08047852 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04605361 0,08042099 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04605361 0,08036355 ! prophase GO:0051324 17 11 0,000 0,04605361 0,08030619 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04605361 0,08024891 ! nucleosome positioning GO:0016584 15 11 0,000 0,04605361 0,08019171 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04605361 0,08013459 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04605361 0,08007756 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04605361 0,0800206 ! apical protein localization GO:0045176 18 11 0,000 0,04605361 0,07996373 ! acid secretion GO:0046717 20 11 0,000 0,04605361 0,07990694 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04605361 0,07985023 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04605361 0,0797936 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04605361 0,07973704 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04605361 0,07968057 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04605361 0,07962418 ! cholesterol efflux GO:0033344 21 11 0,000 0,04605361 0,07956787 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04605361 0,07951164 ! oocyte development GO:0048599 20 11 0,000 0,04605361 0,07945549 ! germ cell migration GO:0008354 26 11 0,000 0,04605361 0,07939941 ! embryonic gut development GO:0048566 19 11 0,000 0,04605361 0,07934342 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04605361 0,0792875 ! activation of innate immune response GO:0002218 16 11 0,000 0,04605361 0,07923167 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04605361 0,07917591 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04605361 0,07912023 ! lysogeny GO:0030069 22 11 0,000 0,04605361 0,07906463 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04605361 0,07900911 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04605361 0,07895366 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04605361 0,0788983 ! regulation of embryonic development GO:0045995 35 11 0,000 0,04605361 0,07884301 ! nucleus localization GO:0051647 22 11 0,000 0,04605361 0,07878779 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,0462152 0,07900891 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05013432 0,08564905 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05013432 0,0855892 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,05013432 0,08552943 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05013432 0,08546974 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,05013432 0,08541014 ! mating GO:0007618 17 12 0,000 0,05013432 0,08535062 ! protein complex disassembly GO:0043241 28 12 0,000 0,05013432 0,08529119 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05013432 0,08523183 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05013432 0,08517256 ! hippocampus development GO:0021766 29 12 0,000 0,05013432 0,08511337 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05013432 0,08505427 ! T cell proliferation GO:0042098 32 12 0,000 0,05013432 0,08499524 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05013432 0,0849363 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05013432 0,08487744 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05013432 0,08481866 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05013432 0,08475996 ! drug transport GO:0015893 16 12 0,000 0,05013432 0,08470134 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05013432 0,08464281 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05013432 0,08458435 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05013432 0,08452598 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05013432 0,08446768 ! focal adhesion formation GO:0048041 37 12 0,000 0,05013432 0,08440947 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05013432 0,08435134 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05013432 0,08429328 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05013432 0,08423531 ! lipid digestion GO:0044241 21 12 0,000 0,05013432 0,08417742 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05013432 0,0841196 ! entry into host cell GO:0030260 34 12 0,000 0,05013432 0,08406187 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05013432 0,08400421 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05013432 0,08394664 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05013432 0,08388914 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05013432 0,08383172 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05013432 0,08377438 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05013432 0,08371712 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05013432 0,08365993 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05013432 0,08360283 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05013432 0,0835458 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05013432 0,08348885 ! cranial nerve development GO:0021545 23 12 0,000 0,05013432 0,08343198 ! fucose catabolic process GO:0019317 25 12 0,000 0,05013432 0,08337518 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05013432 0,08331846 ! histone acetylation GO:0016573 27 12 0,000 0,05013432 0,08326182 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05013432 0,08320526 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05013432 0,08314877 ! zymogen activation GO:0031638 18 12 0,000 0,05013432 0,08309236 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05013432 0,08303603 ! T cell homeostasis GO:0043029 28 12 0,000 0,05013432 0,08297977 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05013432 0,08292359 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05013432 0,08286748 ! oocyte differentiation GO:0009994 21 12 0,000 0,05013432 0,08281146 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05013432 0,0827555 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05013432 0,08269962 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,05013432 0,08264382 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 15 12 0,000 0,05013432 0,08258809 ! developmental induction GO:0031128 22 12 0,000 0,05013432 0,08253244 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05013432 0,08247686 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05013432 0,08242136 ! response to cold GO:0009409 17 12 0,000 0,05013432 0,08236593 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05013432 0,08231058 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05013432 0,0822553 ! localization within membrane GO:0051668 26 12 0,000 0,05013432 0,0822001 ! T cell activation GO:0042110 189 84 1,000 0,05042702 0,08262455 ! regulation of ligase activity GO:0051340 147 84 1,000 0,05042702 0,08256917 ! negative regulation of growth GO:0045926 168 85 1,000 0,05150089 0,08427104 ! mitochondrion organization GO:0007005 159 87 1,000 0,0536731 0,08776666 ! nucleosome assembly GO:0006334 126 87 1,000 0,0536731 0,08770795 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05419769 0,08850598 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05419769 0,08844686 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05419769 0,08838782 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05419769 0,08832885 ! peroxisomal transport GO:0043574 28 13 0,000 0,05419769 0,08826997 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05419769 0,08821116 ! cartilage condensation GO:0001502 22 13 0,000 0,05419769 0,08815243 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05419769 0,08809378 ! organelle fusion GO:0048284 36 13 0,000 0,05419769 0,08803521 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05419769 0,08797671 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05419769 0,08791829 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05419769 0,08785995 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05419769 0,08780169 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05419769 0,08774351 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05419769 0,0876854 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05419769 0,08762737 ! methionine metabolic process GO:0006555 31 13 0,000 0,05419769 0,08756941 ! plasma membrane organization GO:0007009 27 13 0,000 0,05419769 0,08751153 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05419769 0,08745373 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05419769 0,08739601 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05419769 0,08733836 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05419769 0,08728078 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,05419769 0,08722329 ! cytokine metabolic process GO:0042107 24 13 0,000 0,05419769 0,08716587 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05419769 0,08710852 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05419769 0,08705125 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05419769 0,08699405 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,05419769 0,08693693 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05419769 0,08687989 ! protein homotetramerization GO:0051289 24 13 0,000 0,05419769 0,08682292 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05419769 0,08676602 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05419769 0,0867092 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05419769 0,08665245 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05419769 0,08659578 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05419769 0,08653918 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,05419769 0,08648266 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05419769 0,08642621 ! histone methylation GO:0016571 29 13 0,000 0,05419769 0,08636983 ! chromatin silencing GO:0006342 29 13 0,000 0,05419769 0,08631353 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05419769 0,0862573 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05419769 0,08620114 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05419769 0,08614506 ! spleen development GO:0048536 24 13 0,000 0,05419769 0,08608904 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05419769 0,08603311 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05419769 0,08597724 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05419769 0,08592145 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05419769 0,08586573 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05419769 0,08581008 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05419769 0,0857545 ! insulin secretion GO:0030073 24 13 0,000 0,05419769 0,085699 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05419769 0,08564356 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05419769 0,0855882 ! acrosome reaction GO:0007340 19 13 0,000 0,05419769 0,08553291 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05419769 0,0854777 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05419769 0,08542255 ! chromatin assembly GO:0031497 128 88 1,000 0,05477127 0,08627093 ! regulation of DNA binding GO:0051101 167 89 1,000 0,05587736 0,08795644 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,05699129 0,08965211 ! ossification GO:0001503 205 91 1,000 0,05811297 0,09135777 ! gland development GO:0048732 220 91 1,000 0,05811297 0,09129902 ! defense response to bacterium GO:0042742 112 91 1,000 0,05811297 0,09124035 ! rRNA transcription GO:0009303 28 14 0,000 0,05824379 0,09138701 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05824379 0,09132835 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05824379 0,09126977 ! water transport GO:0006833 21 14 0,000 0,05824379 0,09121126 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05824379 0,09115283 ! non-recombinational repair GO:0000726 29 14 0,000 0,05824379 0,09109448 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05824379 0,09103619 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05824379 0,09097799 ! palate development GO:0060021 32 14 0,000 0,05824379 0,09091985 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05824379 0,09086179 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05824379 0,09080381 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05824379 0,0907459 ! arginine metabolic process GO:0006525 21 14 0,000 0,05824379 0,09068806 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05824379 0,0906303 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05824379 0,09057261 ! regulation of heart rate GO:0002027 25 14 0,000 0,05824379 0,09051499 ! fear response GO:0042596 34 14 0,000 0,05824379 0,09045745 ! organic alcohol transport GO:0015850 29 14 0,000 0,05824379 0,09039998 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05824379 0,09034258 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05824379 0,09028526 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05824379 0,09022801 ! bone mineralization GO:0030282 18 14 0,000 0,05824379 0,09017083 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05824379 0,09011372 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05824379 0,09005669 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05824379 0,08999973 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05824379 0,08994284 ! regulation of cellular pH GO:0030641 27 14 0,000 0,05824379 0,08988602 ! ribosome assembly GO:0042255 18 14 0,000 0,05824379 0,08982927 ! cerebellum development GO:0021549 23 14 0,000 0,05824379 0,0897726 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05824379 0,089716 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05824379 0,08965946 ! response to gamma radiation GO:0010332 30 14 0,000 0,05824379 0,089603 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05824379 0,08954661 ! NADP metabolic process GO:0006739 24 14 0,000 0,05824379 0,0894903 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05824379 0,08943405 ! oxygen transport GO:0015671 22 14 0,000 0,05824379 0,08937787 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05824379 0,08932176 ! male genitalia development GO:0030539 26 14 0,000 0,05824379 0,08926573 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05824379 0,08920976 ! regulation of axon extension GO:0030516 43 14 0,000 0,05824379 0,08915387 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05824379 0,08909804 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05824379 0,08904228 ! bone development GO:0060348 206 92 1,000 0,05924231 0,09051217 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,05924231 0,0904556 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,06037923 0,09213396 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,06037923 0,09207644 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06227269 0,09490467 ! lactation GO:0007595 30 15 0,000 0,06227269 0,0948455 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,06227269 0,09478641 ! reproductive cellular process GO:0048610 22 15 0,000 0,06227269 0,09472739 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06227269 0,09466844 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06227269 0,09460957 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06227269 0,09455077 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,06227269 0,09449204 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06227269 0,09443338 ! copper ion transport GO:0006825 22 15 0,000 0,06227269 0,0943748 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06227269 0,09431629 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06227269 0,09425786 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06227269 0,09419949 ! sulfate transport GO:0008272 27 15 0,000 0,06227269 0,0941412 ! response to cAMP GO:0051591 25 15 0,000 0,06227269 0,09408298 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06227269 0,09402483 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06227269 0,09396676 ! vesicle coating GO:0006901 38 15 0,000 0,06227269 0,09390875 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06227269 0,09385082 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,06227269 0,09379296 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06227269 0,09373517 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,06227269 0,09367745 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06227269 0,0936198 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06227269 0,09356223 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06227269 0,09350472 ! regulation of vasodilation GO:0042312 27 15 0,000 0,06227269 0,09344729 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06227269 0,09338992 ! histone deacetylation GO:0016575 24 15 0,000 0,06227269 0,09333263 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06227269 0,0932754 ! water homeostasis GO:0030104 28 15 0,000 0,06227269 0,09321825 ! cofactor transport GO:0051181 30 15 0,000 0,06227269 0,09316116 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06227269 0,09310415 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06227269 0,09304721 ! intestinal absorption GO:0050892 31 15 0,000 0,06227269 0,09299033 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06227269 0,09293353 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06227269 0,09287679 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06227269 0,09282012 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,06227269 0,09276353 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,06227269 0,092707 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06227269 0,09265054 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06227269 0,09259415 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06227269 0,09253782 ! actin filament polymerization GO:0030041 27 15 0,000 0,06227269 0,09248157 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06227269 0,09242538 ! nucleosome organization GO:0034728 143 95 1,000 0,06267548 0,09296672 ! regulation of T cell activation GO:0050863 175 96 1,000 0,06383463 0,09462865 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,0661746 0,09803793 ! forebrain development GO:0030900 210 98 1,000 0,0661746 0,09797851 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06628447 0,09808175 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06628447 0,09802237 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06628447 0,09796307 ! bone remodeling GO:0046849 28 16 0,000 0,06628447 0,09790385 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06628447 0,09784469 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06628447 0,0977856 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06628447 0,09772659 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06628447 0,09766765 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06628447 0,09760878 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06628447 0,09754998 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06628447 0,09749125 ! startle response GO:0001964 28 16 0,000 0,06628447 0,09743259 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06628447 0,097374 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06628447 0,09731548 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06628447 0,09725703 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06628447 0,09719866 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06628447 0,09714035 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06628447 0,09708211 ! pituitary gland development GO:0021983 30 16 0,000 0,06628447 0,09702394 ! response to osmotic stress GO:0006970 27 16 0,000 0,06628447 0,09696585 ! lysosomal transport GO:0007041 31 16 0,000 0,06628447 0,09690782 ! L-amino acid transport GO:0015807 33 16 0,000 0,06628447 0,09684986 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06628447 0,09679197 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06628447 0,09673415 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06628447 0,09667639 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06628447 0,09661871 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06628447 0,0965611 ! axon cargo transport GO:0008088 46 16 0,000 0,06628447 0,09650355 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06628447 0,09644608 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06628447 0,09638867 ! neuron recognition GO:0008038 40 16 0,000 0,06628447 0,09633133 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06628447 0,09627406 ! tissue regeneration GO:0042246 27 16 0,000 0,06628447 0,09621685 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06628447 0,09615972 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06628447 0,09610265 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06628447 0,09604565 ! biomineral formation GO:0031214 22 16 0,000 0,06628447 0,09598871 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06628447 0,09593185 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06628447 0,09587505 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06628447 0,09581832 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06628447 0,09576166 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06628447 0,09570506 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06628447 0,09564853 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,06628447 0,09559207 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06628447 0,09553567 ! peptide hormone processing GO:0016486 27 16 0,000 0,06628447 0,09547934 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,0702792 0,10117389 ! metencephalon development GO:0022037 32 17 0,000 0,0702792 0,1011143 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,0702792 0,10105479 ! signal complex assembly GO:0007172 47 17 0,000 0,0702792 0,10099534 ! filopodium assembly GO:0046847 42 17 0,000 0,0702792 0,10093597 ! endothelial cell migration GO:0043542 31 17 0,000 0,0702792 0,10087667 ! gene silencing by RNA GO:0031047 38 17 0,000 0,0702792 0,10081743 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,0702792 0,10075827 ! glial cell development GO:0021782 28 17 0,000 0,0702792 0,10069917 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,0702792 0,10064014 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,0702792 0,10058119 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,0702792 0,1005223 ! myoblast differentiation GO:0045445 50 17 0,000 0,0702792 0,10046348 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,0702792 0,10040473 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,0702792 0,10034605 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,0702792 0,10028743 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,0702792 0,10022889 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,0702792 0,10017041 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,0702792 0,100112 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,0702792 0,10005366 ! membrane budding GO:0006900 42 17 0,000 0,0702792 0,09999539 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,0702792 0,09993719 ! regulation of protein binding GO:0043393 33 17 0,000 0,0702792 0,09987905 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,0702792 0,09982098 ! genitalia development GO:0048806 32 17 0,000 0,0702792 0,09976298 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,0702792 0,09970504 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,0702792 0,09964718 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,0702792 0,09958938 ! steroid catabolic process GO:0006706 34 17 0,000 0,0702792 0,09953164 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,0702792 0,09947398 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,0702792 0,09941638 ! gas transport GO:0015669 26 17 0,000 0,0702792 0,09935885 ! organic cation transport GO:0015695 32 17 0,000 0,0702792 0,09930138 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,0702792 0,09924398 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,0702792 0,09918665 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07425695 0,10474003 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07425695 0,10467959 ! limbic system development GO:0021761 40 18 0,000 0,07425695 0,10461922 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07425695 0,10455892 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07425695 0,10449869 ! patterning of blood vessels GO:0001569 43 18 0,000 0,07425695 0,10443853 ! heart looping GO:0001947 34 18 0,000 0,07425695 0,10437844 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07425695 0,10431842 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,07425695 0,10425847 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07425695 0,10419858 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07425695 0,10413877 ! glycine metabolic process GO:0006544 30 18 0,000 0,07425695 0,10407902 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07425695 0,10401934 ! response to retinoic acid GO:0032526 31 18 0,000 0,07425695 0,10395973 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,07425695 0,10390019 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,07425695 0,10384072 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07425695 0,10378131 ! DNA integration GO:0015074 32 18 0,000 0,07425695 0,10372197 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07425695 0,1036627 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07425695 0,1036035 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07425695 0,10354437 ! neural crest cell migration GO:0001755 41 18 0,000 0,07425695 0,1034853 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07425695 0,1034263 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07425695 0,10336737 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07425695 0,1033085 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07425695 0,10324971 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,07425695 0,10319097 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07425695 0,10313231 ! detection of bacterium GO:0016045 22 18 0,000 0,07425695 0,10307371 ! microspike assembly GO:0030035 46 18 0,000 0,07425695 0,10301518 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07425695 0,10295672 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,07425695 0,10289832 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,0782178 0,10832544 ! negative regulation of defense response GO:0031348 27 19 0,000 0,0782178 0,10826406 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,0782178 0,10820276 ! neuron maturation GO:0042551 46 19 0,000 0,0782178 0,10814152 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,0782178 0,10808036 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,0782178 0,10801926 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,0782178 0,10795823 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,0782178 0,10789728 ! inositol metabolic process GO:0006020 33 19 0,000 0,0782178 0,10783638 ! memory GO:0007613 34 19 0,000 0,0782178 0,10777556 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,0782178 0,10771481 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,0782178 0,10765413 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,0782178 0,10759351 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,0782178 0,10753296 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,0782178 0,10747248 ! cerebral cortex development GO:0021987 40 19 0,000 0,0782178 0,10741207 ! pigmentation during development GO:0048066 42 19 0,000 0,0782178 0,10735173 ! response to vitamin A GO:0033189 32 19 0,000 0,0782178 0,10729145 ! heme metabolic process GO:0042168 40 19 0,000 0,0782178 0,10723124 ! neuromuscular junction development GO:0007528 43 19 0,000 0,0782178 0,1071711 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,0782178 0,10711103 ! response to fungus GO:0009620 26 19 0,000 0,0782178 0,10705102 ! protein export from nucleus GO:0006611 40 19 0,000 0,0782178 0,10699108 ! heart process GO:0003015 32 19 0,000 0,0782178 0,10693121 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,0782178 0,10687141 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,0782178 0,10681167 ! visual learning GO:0008542 38 19 0,000 0,0782178 0,106752 ! cellular pigmentation GO:0033059 37 19 0,000 0,0782178 0,10669239 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,0782178 0,10663285 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,0782178 0,10657338 ! vitamin transport GO:0051180 31 19 0,000 0,0782178 0,10651398 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,0782178 0,10645464 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,0782178 0,10639536 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,0782178 0,10633616 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,0782178 0,10627702 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,0782178 0,10621794 ! cilium assembly GO:0042384 38 19 0,000 0,0782178 0,10615893 ! protein secretion GO:0009306 45 20 0,000 0,0821618 0,11144991 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0821618 0,11138806 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0821618 0,11132628 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0821618 0,11126457 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,0821618 0,11120293 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0821618 0,11114135 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0821618 0,11107985 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,0821618 0,11101841 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0821618 0,11095704 ! response to vitamin GO:0033273 36 20 0,000 0,0821618 0,11089574 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0821618 0,1108345 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,0821618 0,11077334 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0821618 0,11071224 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0821618 0,11065121 ! response to alkaloid GO:0043279 38 20 0,000 0,0821618 0,11059024 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0821618 0,11052934 GO:0016101|diterpenoid metabolic process, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,0821618 0,11046851 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,0821618 0,11040775 ! actin filament bundle formation GO:0051017 47 20 0,000 0,0821618 0,11034705 ! body fluid secretion GO:0007589 33 20 0,000 0,0821618 0,11028642 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0821618 0,11022586 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0821618 0,11016536 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0821618 0,11010493 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0821618 0,11004456 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0821618 0,10998427 ! cell-cell junction organization GO:0045216 43 20 0,000 0,0821618 0,10992403 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,0821618 0,10986387 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,0821618 0,10980377 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0821618 0,10974373 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0821618 0,10968376 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0821618 0,10962386 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0821618 0,10956402 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,0821618 0,10950425 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0821618 0,10944454 ! regulation of cell killing GO:0031341 46 21 0,000 0,08608905 0,11461337 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08608905 0,11455095 ! lipid phosphorylation GO:0046834 43 21 0,000 0,08608905 0,11448859 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08608905 0,1144263 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08608905 0,11436408 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08608905 0,11430193 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08608905 0,11423984 ! ovarian follicle development GO:0001541 39 21 0,000 0,08608905 0,11417782 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08608905 0,11411587 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,08608905 0,11405398 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08608905 0,11399216 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,08608905 0,11393041 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08608905 0,11386873 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08608905 0,11380711 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08608905 0,11374556 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08608905 0,11368408 ! sensory perception of pain GO:0019233 33 21 0,000 0,08608905 0,11362266 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08608905 0,11356131 ! diencephalon development GO:0021536 36 21 0,000 0,08608905 0,11350002 ! collagen fibril organization GO:0030199 62 21 0,000 0,08608905 0,1134388 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08608905 0,11337765 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08608905 0,11331656 ! collagen catabolic process GO:0030574 29 21 0,000 0,08608905 0,11325554 ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08608905 0,11319459 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08608905 0,1131337 ! actin filament-based movement GO:0030048 47 21 0,000 0,08608905 0,11307287 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,08608905 0,11301211 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,0899996 0,11808218 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,0899996 0,1180188 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,0899996 0,11795548 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,0899996 0,11789223 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,0899996 0,11782905 ! microtubule-based transport GO:0010970 59 22 0,000 0,0899996 0,11776594 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,0899996 0,1177029 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,0899996 0,11763992 ! vacuolar transport GO:0007034 41 22 0,000 0,0899996 0,11757701 ! central nervous system neuron development GO:0021954 47 22 0,000 0,0899996 0,11751417 ! fucose metabolic process GO:0006004 44 22 0,000 0,0899996 0,1174514 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,0899996 0,11738869 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,0899996 0,11732605 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,0899996 0,11726348 ! ureteric bud development GO:0001657 50 22 0,000 0,0899996 0,11720097 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,0899996 0,11713853 ! cytolysis GO:0019835 27 22 0,000 0,0899996 0,11707615 ! renal system process GO:0003014 42 22 0,000 0,0899996 0,11701385 ! vasodilation GO:0042311 40 22 0,000 0,0899996 0,1169516 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,0899996 0,11688943 ! G1 phase GO:0051318 44 22 0,000 0,0899996 0,11682732 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,0899996 0,11676528 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,0899996 0,1167033 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,0899996 0,11664139 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,0899996 0,11657954 ! sarcomere organization GO:0045214 32 22 0,000 0,0899996 0,11651776 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,0899996 0,11645605 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,0899996 0,1163944 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,0899996 0,11633281 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,0899996 0,11627129 ! gut development GO:0048565 44 22 0,000 0,0899996 0,11620984 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,0899996 0,11614845 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,0899996 0,11608713 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,0899996 0,11602587 ! protein stabilization GO:0050821 41 22 0,000 0,0899996 0,11596467 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09389352 0,12091823 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09389352 0,12085452 ! viral genome replication GO:0019079 44 23 0,000 0,09389352 0,12079088 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,09389352 0,1207273 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09389352 0,1206638 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09389352 0,12060036 ! regeneration GO:0031099 42 23 0,000 0,09389352 0,12053698 ! axis specification GO:0009798 43 23 0,000 0,09389352 0,12047368 ! visual behavior GO:0007632 46 23 0,000 0,09389352 0,12041044 ! response to ethanol GO:0045471 47 23 0,000 0,09389352 0,12034726 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09389352 0,12028415 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,09389352 0,12022111 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09389352 0,12015813 ! peroxisome organization GO:0007031 43 23 0,000 0,09389352 0,12009522 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,09389352 0,12003238 ! vesicle targeting GO:0006903 49 23 0,000 0,09389352 0,1199696 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,09389352 0,11990689 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,09389352 0,11984424 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09389352 0,11978166 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09389352 0,11971914 ! DNA modification GO:0006304 36 23 0,000 0,09389352 0,11965669 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,09389352 0,11959431 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09389352 0,11953198 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09389352 0,11946973 ! cell-cell recognition GO:0009988 28 23 0,000 0,09389352 0,11940754 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,09389352 0,11934541 GO:0006099|tricarboxylic acid cycle, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0977709 0,12420921 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0977709 0,12414465 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0977709 0,12408016 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0977709 0,12401573 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0977709 0,12395138 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0977709 0,12388709 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0977709 0,12382286 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0977709 0,12375871 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0977709 0,12369462 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0977709 0,12363059 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0977709 0,12356663 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0977709 0,12350274 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0977709 0,12343892 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0977709 0,12337516 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0977709 0,12331146 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0977709 0,12324783 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0977709 0,12318427 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0977709 0,12312077 ! membrane depolarization GO:0051899 45 24 0,000 0,0977709 0,12305734 ! pallium development GO:0021543 56 24 0,000 0,0977709 0,12299398 ! oogenesis GO:0048477 44 24 0,000 0,0977709 0,12293068 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0977709 0,12286744 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0977709 0,12280427 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0977709 0,12274116 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0977709 0,12267812 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0977709 0,12261515 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0977709 0,12255223 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0977709 0,12248939 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0977709 0,1224266 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0977709 0,12236388 ! regulation of amine transport GO:0051952 41 24 0,000 0,0977709 0,12230123 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,0977709 0,12223864 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,10163179 0,12700075 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,10163179 0,12693582 ! leukocyte adhesion GO:0007159 55 25 0,000 0,10163179 0,12687095 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,10163179 0,12680616 ! phototransduction GO:0007602 37 25 0,000 0,10163179 0,12674143 ! keratinization GO:0031424 37 25 0,000 0,10163179 0,12667676 ! vasculogenesis GO:0001570 49 25 0,000 0,10163179 0,12661217 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10163179 0,12654763 ! receptor metabolic process GO:0043112 53 25 0,000 0,10163179 0,12648317 ! chromosome condensation GO:0030261 48 25 0,000 0,10163179 0,12641877 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,10163179 0,12635443 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,10163179 0,12629016 ! immunoglobulin production GO:0002377 62 25 0,000 0,10163179 0,12622596 GO:0002440|production of molecular mediator of immune response, ! liver development GO:0001889 55 25 0,000 0,10163179 0,12616182 ! protein tetramerization GO:0051262 57 25 0,000 0,10163179 0,12609774 ! initiation of viral infection GO:0019059 60 26 0,000 0,10547626 0,13080128 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,10547626 0,13073491 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,10547626 0,13066862 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,10547626 0,13060239 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,10547626 0,13053623 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,10547626 0,13047013 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,10547626 0,13040411 ! digestive system process GO:0022600 49 26 0,000 0,10547626 0,13033815 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,10547626 0,13027225 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,10547626 0,13020642 ! osteoblast differentiation GO:0001649 63 26 0,000 0,10547626 0,13014066 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,10547626 0,13007497 ! neural crest cell development GO:0014032 59 26 0,000 0,10547626 0,13000934 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,10547626 0,12994378 ! negative regulation of cell development GO:0010721 83 26 0,000 0,10547626 0,12987828 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,10547626 0,12981285 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,10547626 0,12974749 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,10547626 0,12968219 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,10547626 0,12961696 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,10547626 0,12955179 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,10547626 0,12948669 ! blastocyst development GO:0001824 50 26 0,000 0,10547626 0,12942165 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,10547626 0,12935668 ! neural tube closure GO:0001843 58 26 0,000 0,10547626 0,12929178 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,10547626 0,12922694 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,10547626 0,12916216 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1093044 0,13378289 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1093044 0,13371589 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1093044 0,13364897 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1093044 0,13358211 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1093044 0,13351532 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1093044 0,1334486 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1093044 0,13338194 ! iron ion transport GO:0006826 65 27 0,000 0,1093044 0,13331535 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1093044 0,13324882 ! tube lumen formation GO:0035148 59 27 0,000 0,1093044 0,13318236 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1093044 0,13311597 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,1093044 0,13304965 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,1093044 0,13298339 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1093044 0,13291719 ! response to toxin GO:0009636 49 27 0,000 0,1093044 0,13285107 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1093044 0,132785 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,1093044 0,13271901 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1093044 0,13265308 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,1093044 0,13258721 ! neuron fate commitment GO:0048663 52 28 0,000 0,11311625 0,13714293 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,11311625 0,13707491 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,11311625 0,13700695 ! protein amino acid acylation GO:0043543 59 28 0,000 0,11311625 0,13693905 ! vesicle docking GO:0048278 55 28 0,000 0,11311625 0,13687123 ! circadian rhythm GO:0007623 56 28 0,000 0,11311625 0,13680347 ! dendrite development GO:0016358 67 28 0,000 0,11311625 0,13673578 ! fat cell differentiation GO:0045444 57 28 0,000 0,11311625 0,13666815 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,11311625 0,1366006 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,11311625 0,13653311 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,11311625 0,13646568 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,11311625 0,13639833 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,11311625 0,13633104 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,11311625 0,13626381 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,11311625 0,13619665 ! glutathione metabolic process GO:0006749 42 28 0,000 0,11311625 0,13612956 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,11311625 0,13606254 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,11311625 0,13599558 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,11311625 0,13592868 ! translational initiation GO:0006413 66 29 0,000 0,1169119 0,14042074 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,1169119 0,14035174 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,1169119 0,1402828 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,1169119 0,14021393 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,1169119 0,14014513 ! autophagy GO:0006914 47 29 0,000 0,1169119 0,1400764 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,1169119 0,14000774 ! primary neural tube formation GO:0014020 61 29 0,000 0,1169119 0,13993914 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,1169119 0,13987061 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,1169119 0,13980215 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,1169119 0,13973375 ! somitogenesis GO:0001756 52 29 0,000 0,1169119 0,13966542 ! synaptogenesis GO:0007416 46 29 0,000 0,1169119 0,13959716 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,1169119 0,13952896 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,1169119 0,13946083 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,1169119 0,13939277 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,12069142 0,14382885 ! phenol metabolic process GO:0018958 56 30 0,000 0,12069142 0,14375872 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,12069142 0,14368866 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,12069142 0,14361867 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,12069142 0,14354875 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,12069142 0,1434789 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,12069142 0,14340911 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,12069142 0,14333939 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,12069142 0,14326974 ! myofibril assembly GO:0030239 50 30 0,000 0,12069142 0,14320016 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,12069142 0,14313065 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,12069142 0,1430612 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,12069142 0,14299182 ! cell fate determination GO:0001709 64 30 0,000 0,12069142 0,14292251 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,12069142 0,14285326 ! phospholipid transport GO:0015914 65 30 0,000 0,12069142 0,14278408 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,12069142 0,14271497 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,12069142 0,14264593 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,12069142 0,14257695 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,12069142 0,14250804 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,12445486 0,14688078 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,12445486 0,14680986 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,12445486 0,14673901 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,12445486 0,14666822 ! cell junction assembly GO:0034329 85 31 0,000 0,12445486 0,1465975 ! regulation of innate immune response GO:0045088 57 31 0,000 0,12445486 0,14652685 ! ovulation cycle process GO:0022602 55 31 0,000 0,12445486 0,14645627 ! male gonad development GO:0008584 56 31 0,000 0,12445486 0,14638576 ! iron ion homeostasis GO:0055072 60 31 0,000 0,12445486 0,14631531 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,12445486 0,14624494 ! detection of light stimulus GO:0009583 44 31 0,000 0,12445486 0,14617463 ! natural killer cell activation GO:0030101 50 31 0,000 0,12445486 0,14610438 ! cofactor catabolic process GO:0051187 54 31 0,000 0,12445486 0,14603421 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,12445486 0,1459641 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,12445486 0,14589406 ! eye morphogenesis GO:0048592 65 31 0,000 0,12445486 0,14582409 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,12445486 0,14575418 ! collagen metabolic process GO:0032963 49 32 0,000 0,1282023 0,15007102 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1282023 0,14999915 ! spindle organization GO:0007051 50 32 0,000 0,1282023 0,14992734 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,1282023 0,14985561 ! metanephros development GO:0001656 81 32 0,000 0,1282023 0,14978394 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,1282023 0,14971234 ! muscle cell development GO:0055001 52 32 0,000 0,1282023 0,14964081 ! mesoderm formation GO:0001707 73 32 0,000 0,1282023 0,14956935 ! ovulation cycle GO:0042698 57 32 0,000 0,1282023 0,14949796 ! peripheral nervous system development GO:0007422 68 32 0,000 0,1282023 0,14942663 ! BMP signaling pathway GO:0030509 71 32 0,000 0,1282023 0,14935537 ! hindbrain development GO:0030902 65 32 0,000 0,1282023 0,14928419 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,1282023 0,14921306 ! gene silencing GO:0016458 71 32 0,000 0,1282023 0,14914201 ! regulation of pH GO:0006885 56 33 0,000 0,13193381 0,15340994 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,13193381 0,15333696 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,13193381 0,15326405 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,13193381 0,1531912 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,13193381 0,15311843 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,13193381 0,15304572 ! response to ionizing radiation GO:0010212 74 33 0,000 0,13193381 0,15297309 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,13193381 0,15290052 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,13193381 0,15282802 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,13193381 0,15275559 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,13193381 0,15268323 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,13193381 0,15261093 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,13193381 0,15253871 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,13564945 0,15676045 ! glial cell differentiation GO:0010001 67 34 0,000 0,13564945 0,15668633 ! post-embryonic development GO:0009791 76 34 0,000 0,13564945 0,15661229 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,13564945 0,15653831 ! cholesterol transport GO:0030301 62 34 0,000 0,13564945 0,1564644 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,13564945 0,15639056 ! spliceosome assembly GO:0000245 75 34 0,000 0,13564945 0,15631679 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,13564945 0,15624309 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,13564945 0,15616946 ! formation of primary germ layer GO:0001704 76 34 0,000 0,13564945 0,1560959 ! cell fate specification GO:0001708 56 34 0,000 0,13564945 0,15602241 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,13564945 0,15594899 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,13934929 0,16012714 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,13934929 0,16005186 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,13934929 0,15997665 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,13934929 0,1599015 ! membrane docking GO:0022406 69 35 0,000 0,13934929 0,15982643 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,13934929 0,15975143 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,13934929 0,1596765 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,13934929 0,15960164 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,13934929 0,15952685 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,13934929 0,15945213 ! telencephalon development GO:0021537 81 35 0,000 0,13934929 0,15937748 ! sterol transport GO:0015918 63 35 0,000 0,13934929 0,1593029 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,13934929 0,15922839 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,13934929 0,15915395 ! placenta development GO:0001890 53 35 0,000 0,13934929 0,15907958 ! vesicle localization GO:0051648 70 35 0,000 0,13934929 0,15900528 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,14303339 0,16313285 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,14303339 0,16305673 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,14303339 0,16298068 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,14303339 0,1629047 ! positive regulation of cell development GO:0010720 85 36 0,000 0,14303339 0,16282879 ! protein targeting to membrane GO:0006612 75 36 0,000 0,14303339 0,16275295 ! regulation of proteolysis GO:0030162 77 36 0,000 0,14303339 0,16267718 ! aerobic respiration GO:0009060 56 36 0,000 0,14303339 0,16260148 ! cytokine production GO:0001816 68 36 0,000 0,14303339 0,16252585 ! embryonic organ development GO:0048568 67 36 0,000 0,14303339 0,16245029 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,14303339 0,1623748 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,14670183 0,16646195 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,14670183 0,16638467 ! sister chromatid segregation GO:0000819 65 37 0,000 0,14670183 0,16630746 ! odontogenesis GO:0042476 74 37 0,000 0,14670183 0,16623032 ! actomyosin structure organization GO:0031032 68 37 0,000 0,14670183 0,16615325 ! cell junction organization GO:0034330 96 37 0,000 0,14670183 0,16607626 ! tissue remodeling GO:0048771 78 37 0,000 0,14670183 0,16599934 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,14670183 0,16592249 ! female gonad development GO:0008585 71 37 0,000 0,14670183 0,16584571 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,14670183 0,165769 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,15035467 0,16981806 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,15035467 0,16973958 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,15035467 0,16966118 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,15035467 0,16958285 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,15035467 0,16950459 ! regulation of protein stability GO:0031647 77 38 0,000 0,15035467 0,16942641 ! spermatid development GO:0007286 69 38 0,000 0,15035467 0,1693483 ! glycogen metabolic process GO:0005977 63 38 0,000 0,15035467 0,16927026 ! pigment metabolic process GO:0042440 87 38 0,000 0,15035467 0,16919229 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,15035467 0,16911439 ! neural tube formation GO:0001841 79 38 0,000 0,15035467 0,16903656 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,15399197 0,17304618 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,15399197 0,17296661 ! negative regulation of binding GO:0051100 71 39 0,000 0,15399197 0,17288713 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,15399197 0,17280771 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,15399197 0,17272837 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,15399197 0,1726491 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,15399197 0,1725699 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,15399197 0,17249078 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,15399197 0,17241173 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,15399197 0,17233275 ! glucan metabolic process GO:0044042 64 39 0,000 0,15399197 0,17225384 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,15761381 0,1762245 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,15761381 0,17614388 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,15761381 0,17606334 ! learning GO:0007612 82 40 0,000 0,15761381 0,17598287 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,15761381 0,17590248 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,15761381 0,17582216 ! lipid homeostasis GO:0055088 75 40 0,000 0,15761381 0,17574191 ! mismatch repair GO:0006298 58 40 0,000 0,15761381 0,17566174 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,15761381 0,17558164 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,15761381 0,17550161 ! RNA export from nucleus GO:0006405 61 41 0,000 0,16122024 0,17943555 ! mRNA catabolic process GO:0006402 79 41 0,000 0,16122024 0,17935384 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,16122024 0,17927221 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,16122024 0,17919064 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,16122024 0,17910916 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,16122024 0,17902774 ! gliogenesis GO:0042063 91 41 0,000 0,16122024 0,1789464 ! feeding behavior GO:0007631 69 41 0,000 0,16122024 0,17886514 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,16122024 0,17878395 ! mesenchymal cell development GO:0014031 94 41 0,000 0,16122024 0,17870283 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,16122024 0,17862178 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,16122024 0,17854081 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,16122024 0,17845992 ! spermatid differentiation GO:0048515 73 41 0,000 0,16122024 0,17837909 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,16122024 0,17829834 ! RNA modification GO:0009451 64 41 0,000 0,16122024 0,17821766 ! ear morphogenesis GO:0042471 64 42 0,000 0,16481133 0,18210496 ! organic ether metabolic process GO:0018904 59 42 0,000 0,16481133 0,18202264 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,16481133 0,18194039 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,16481133 0,18185821 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,16481133 0,1817761 ! cytokinesis GO:0000910 84 42 0,000 0,16481133 0,18169408 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,16481133 0,18161212 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,16838714 0,1854688 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,16838714 0,18538522 ! regulation of tube size GO:0035150 76 43 0,000 0,16838714 0,18530171 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,16838714 0,18521828 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,16838714 0,18513492 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,16838714 0,18505164 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,16838714 0,18496843 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,16838714 0,1848853 ! segmentation GO:0035282 78 43 0,000 0,16838714 0,18480224 ! ion transmembrane transport GO:0034220 79 43 0,000 0,16838714 0,18471926 ! neuron migration GO:0001764 85 43 0,000 0,16838714 0,18463635 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,16838714 0,18455352 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,17194775 0,18837146 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,17194775 0,18828703 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,17194775 0,18820267 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,17194775 0,18811839 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,17194775 0,18803418 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,17549322 0,19182547 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,17549322 0,19173968 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,17549322 0,19165397 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,17549322 0,19156833 ! B cell differentiation GO:0030183 124 45 0,000 0,17549322 0,19148277 ! female gamete generation GO:0007292 71 45 0,000 0,17549322 0,19139729 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,17549322 0,19131188 ! developmental growth GO:0048589 88 45 0,000 0,17549322 0,19122655 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,1790236 0,19498647 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,1790236 0,19489958 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,1790236 0,19481276 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,1790236 0,19472602 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,1790236 0,19463936 ! pigmentation GO:0043473 103 46 0,000 0,1790236 0,19455278 ! neural tube development GO:0021915 91 47 0,000 0,18253896 0,19828488 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,18253896 0,19819675 ! response to insulin stimulus GO:0032868 98 47 0,000 0,18253896 0,1981087 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,18603937 0,20181802 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,18603937 0,20172845 ! mitochondrial transport GO:0006839 94 48 0,000 0,18603937 0,20163895 ! cellular component disassembly GO:0022411 89 48 0,000 0,18603937 0,20154953 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,18603937 0,20146019 ! endosome transport GO:0016197 127 48 0,000 0,18603937 0,20137093 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,18603937 0,20128175 ! male sex differentiation GO:0046661 93 48 0,000 0,18603937 0,20119265 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,18603937 0,20110362 ! methylation GO:0032259 97 48 0,000 0,18603937 0,20101468 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,18952489 0,20469024 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,18952489 0,20459979 ! JNK cascade GO:0007254 106 49 0,000 0,18952489 0,20450941 ! regulation of ion transport GO:0043269 86 50 0,000 0,19299559 0,20816257 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,19299559 0,2080707 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,19299559 0,20797892 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,19299559 0,20788722 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,19645151 0,21151655 ! viral infectious cycle GO:0019058 104 51 0,000 0,19645151 0,21142337 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,19645151 0,21133027 ! peptide metabolic process GO:0006518 80 51 0,000 0,19645151 0,21123726 ! Notch signaling pathway GO:0007219 111 52 0,000 0,19989274 0,21484292 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,19989274 0,21474844 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,19989274 0,21465405 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,19989274 0,21455973 ! excretion GO:0007588 87 52 0,000 0,19989274 0,21446551 ! histone modification GO:0016570 104 52 0,000 0,19989274 0,21437136 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,19989274 0,2142773 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,19989274 0,21418331 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,19989274 0,21408941 ! amino acid activation GO:0043038 98 52 0,000 0,19989274 0,2139956 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,20331932 0,21756859 ! inner ear development GO:0048839 89 53 0,000 0,20331932 0,21747334 ! chromatin remodeling GO:0006338 122 53 0,000 0,20331932 0,21737816 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,20331932 0,21728307 ! vesicle organization GO:0016050 127 53 0,000 0,20331932 0,21718806 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,20331932 0,21709314 ! synapse organization GO:0050808 102 53 0,000 0,20331932 0,2169983 ! regulation of translational initiation GO:0006446 87 54 0,000 0,20673132 0,22054351 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,20673132 0,22044724 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,20673132 0,22035106 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 0,000 0,20673132 0,22025496 ! membrane fusion GO:0006944 122 54 0,000 0,20673132 0,22015895 ! covalent chromatin modification GO:0016569 115 54 0,000 0,20673132 0,22006302 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,20673132 0,21996717 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,20673132 0,21987141 ! RNA catabolic process GO:0006401 103 55 0,000 0,21012881 0,22338759 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,21012881 0,22329043 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,21012881 0,22319334 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,21012881 0,22309634 ! cell recognition GO:0008037 98 55 0,000 0,21012881 0,22299943 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,21012881 0,2229026 ! cell maturation GO:0048469 107 55 0,000 0,21012881 0,22280585 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,21012881 0,22270919 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,21351184 0,22619663 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,21351184 0,22609859 ! RNA elongation GO:0006354 90 56 0,000 0,21351184 0,22600062 ! chloride transport GO:0006821 102 57 0,000 0,21688048 0,22946688 ! muscle fiber development GO:0048747 131 57 0,000 0,21688048 0,22936754 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,21688048 0,22926829 ! heart morphogenesis GO:0003007 105 57 0,000 0,21688048 0,22916913 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,21688048 0,22907005 ! regulation of actin filament length GO:0030832 118 58 0,000 0,22023479 0,23251235 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,22023479 0,23241191 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,22023479 0,23231156 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,22023479 0,2322113 ! gastrulation GO:0007369 122 58 0,000 0,22023479 0,23211112 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,22023479 0,23201103 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,22023479 0,23191103 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,22023479 0,23181111 ! nuclear export GO:0051168 110 59 0,000 0,22357482 0,23522536 ! establishment of organelle localization GO:0051656 122 59 0,000 0,22357482 0,2351241 ! DNA catabolic process GO:0006308 94 60 0,000 0,22690063 0,23851904 ! regulation of endocytosis GO:0030100 104 60 0,000 0,22690063 0,23841645 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,22690063 0,23831395 ! kidney development GO:0001822 133 60 0,000 0,22690063 0,23821154 ! regulation of cellular component size GO:0032535 125 61 0,000 0,2302123 0,24158447 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,2302123 0,24148074 GO:0032313|regulation of Rab GTPase activity, ! camera-type eye development GO:0043010 126 61 0,000 0,2302123 0,2413771 ! proton transport GO:0015992 117 61 0,000 0,2302123 0,24127355 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,23350987 0,24462462 ! tRNA processing GO:0008033 102 62 0,000 0,23350987 0,24451976 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,23350987 0,244415 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,23679341 0,24774574 ! regulation of mitosis GO:0007088 112 63 0,000 0,23679341 0,24763968 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,23679341 0,24753372 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,23679341 0,24742784 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,23679341 0,24732206 ! hydrogen transport GO:0006818 121 64 0,000 0,24006297 0,25062985 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,24006297 0,25052278 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,24006297 0,25041581 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,24006297 0,25030894 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,24006297 0,25020215 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,24331862 0,25348716 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,24331862 0,25337911 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,24331862 0,25327115 ! ear development GO:0043583 114 66 0,000 0,24656041 0,25653624 ! gonad development GO:0008406 115 66 0,000 0,24656041 0,25642703 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,24978841 0,25967365 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,24978841 0,2595632 ! secondary metabolic process GO:0019748 125 67 0,000 0,24978841 0,25945284 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,25300266 0,26267977 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,25300266 0,26256819 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 137 68 0,000 0,25300266 0,26245669 ! adaptive immune response GO:0002250 126 68 0,000 0,25300266 0,26234529 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,25620324 0,26555134 ! lung development GO:0030324 165 69 0,000 0,25620324 0,26543873 ! urogenital system development GO:0001655 149 69 0,000 0,25620324 0,2653262 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,25620324 0,26521378 ! developmental maturation GO:0021700 128 69 0,000 0,25620324 0,26510145 ! single fertilization GO:0007338 83 69 0,000 0,25620324 0,26498921 ! cell redox homeostasis GO:0045454 114 70 0,000 0,25939019 0,26817192 ! germ cell development GO:0007281 133 70 0,000 0,25939019 0,26805848 ! activation of immune response GO:0002253 120 70 0,000 0,25939019 0,26794513 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,25939019 0,26783188 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,26256358 0,27099401 ! appendage morphogenesis GO:0035107 150 72 0,000 0,26572345 0,27413953 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 0,000 0,26572345 0,27402381 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,26572345 0,27390819 ! appendage development GO:0048736 151 73 0,000 0,26886988 0,27703463 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,26886988 0,27691784 ! respiratory system development GO:0060541 175 74 0,000 0,27200291 0,2800266 ! transition metal ion transport GO:0000041 143 75 0,000 0,27512261 0,28311901 ! reproductive structure development GO:0048608 131 75 0,000 0,27512261 0,2829998 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,27512261 0,28288069 ! eye development GO:0001654 155 75 0,000 0,27512261 0,28276169 ! rhythmic process GO:0048511 142 75 0,000 0,27512261 0,28264278 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,27822902 0,28571395 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,27822902 0,28559391 ! learning or memory GO:0007611 161 76 0,000 0,27822902 0,28547396 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,27822902 0,28535411 ! regulation of blood pressure GO:0008217 134 76 0,000 0,27822902 0,28523437 ! amine catabolic process GO:0009310 136 77 0,000 0,28132221 0,28828446 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,28132221 0,28816359 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,28132221 0,28804281 ! regulation of catabolic process GO:0009894 173 77 0,000 0,28132221 0,28792214 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,28440223 0,29095253 ! antigen processing and presentation GO:0019882 117 78 0,000 0,28440223 0,29083074 ! fertilization GO:0009566 99 78 0,000 0,28440223 0,29070905 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,28746913 0,29372107 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,28746913 0,29359828 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,28746913 0,29347559 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,29052298 0,29646936 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,29052298 0,29634557 ! muscle cell differentiation GO:0042692 178 81 0,000 0,29356382 0,29932238 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,29356382 0,29919751 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,29659172 0,30215745 ! protein import into nucleus GO:0006606 174 82 0,000 0,29659172 0,3020315 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,29960672 0,30497468 ! exocytosis GO:0006887 153 83 0,000 0,29960672 0,30484766 ! response to drug GO:0042493 149 83 0,000 0,29960672 0,30472074 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,29960672 0,30459394 ! nuclear import GO:0051170 177 83 0,000 0,29960672 0,30446723 ! inorganic anion transport GO:0015698 156 83 0,000 0,29960672 0,30434063 ! response to nutrient GO:0007584 135 84 0,000 0,30260889 0,30726248 ! digestion GO:0007586 130 84 0,000 0,30260889 0,30713482 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,30559827 0,31004011 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,30559827 0,3099114 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,30559827 0,30978281 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,30559827 0,30965432 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,30559827 0,30952594 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,30857492 0,31241133 ! regulation of lyase activity GO:0051339 169 86 0,000 0,30857492 0,31228191 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,3115389 0,31515094 ! cellular respiration GO:0045333 143 88 0,000 0,31449025 0,31800483 ! amine biosynthetic process GO:0009309 146 88 0,000 0,31449025 0,31787326 ! sensory perception of smell GO:0007608 117 88 0,000 0,31449025 0,3177418 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,31449025 0,31761045 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,31742903 0,32044592 ! tube morphogenesis GO:0035239 194 89 0,000 0,31742903 0,32031356 ! cellular defense response GO:0006968 123 89 0,000 0,31742903 0,32018131 ! protein localization in nucleus GO:0034504 192 89 0,000 0,31742903 0,32004916 ! regulation of neurological system process GO:0031644 175 89 0,000 0,31742903 0,31991713 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,3203553 0,32273319 ! response to unfolded protein GO:0006986 139 90 0,000 0,3203553 0,32260016 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,3232691 0,32540025 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! vitamin metabolic process GO:0006766 153 93 0,000 0,32905953 0,33109243 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,33193626 0,33384944 ! female pregnancy GO:0007565 166 94 0,000 0,33193626 0,33371205 ! sterol metabolic process GO:0016125 166 94 0,000 0,33193626 0,33357478 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,33480074 0,33631505 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,33480074 0,33617682 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,33480074 0,3360387 ! sex differentiation GO:0007548 171 96 0,000 0,33765301 0,33876234 ! response to protein stimulus GO:0051789 158 96 0,000 0,33765301 0,33862328 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,34049314 0,34133144 ! transcription initiation GO:0006352 171 97 0,000 0,34049314 0,34119144 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,34332116 0,34388421 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,34894112 0,34937015 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,34894112 0,34922702 ! positive regulation of immune response GO:0050778 175 100 0,000 0,34894112 0,34908401 ! hormone metabolic process GO:0042445 171 100 0,000 0,34894112 0,34894112