pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6937-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 7,000 2,993E-10 7,202E-07 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 4,000 3,981E-10 4,789E-07 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 4,000 1,774E-09 1,423E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 7,000 1,792E-09 1,078E-06 ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 6,015E-09 2,894E-06 ! interphase GO:0051325 213 98 8,000 7,933E-09 3,181E-06 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 2,796E-07 9,61E-05 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 3,000 3,941E-07 1,185E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 4,285E-07 1,146E-04 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of cellular catabolic process GO:0031331 31 12 3,000 5,884E-07 1,416E-04 ! response to UV GO:0009411 104 53 5,000 7,624E-07 1,668E-04 ! regulation of monooxygenase activity GO:0032768 33 13 3,000 8,46E-07 1,696E-04 ! positive regulation of cell migration GO:0030335 126 57 5,000 1,181E-06 2,187E-04 ! positive regulation of catabolic process GO:0009896 64 32 4,000 1,274E-06 2,19E-04 ! placenta development GO:0001890 53 34 4,000 1,744E-06 2,797E-04 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 2,081E-06 3,13E-04 ! positive regulation of glycolysis GO:0045821 14 5 2,000 2,081E-06 2,946E-04 ! positive regulation of cell motion GO:0051272 146 64 5,000 2,358E-06 3,152E-04 ! cell cycle arrest GO:0007050 213 100 6,000 2,429E-06 3,076E-04 ! germ cell development GO:0007281 118 65 5,000 2,585E-06 3,11E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 2,764E-06 3,166E-04 ! negative regulation of cell size GO:0045792 134 69 5,000 3,678E-06 4,022E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 4,144E-06 4,335E-04 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 2,000 4,144E-06 4,154E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 5,548E-06 5,339E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 5,548E-06 5,134E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 5,776E-06 5,147E-04 ! regulation of catabolic process GO:0009894 161 76 5,000 6,48E-06 5,568E-04 ! cytokinesis during cell cycle GO:0033205 11 7 2,000 7,22E-06 5,99E-04 ! positive regulation of monooxygenase activity GO:0032770 12 7 2,000 7,22E-06 5,791E-04 ! response to hypoxia GO:0001666 171 81 5,000 9,385E-06 7,284E-04 ! response to oxygen levels GO:0070482 176 83 5,000 1,081E-05 8,126E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,15E-05 8,386E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,15E-05 8,139E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,15E-05 7,906E-04 ! negative regulation of growth GO:0045926 155 84 5,000 1,158E-05 7,74E-04 ! regulation of cellular catabolic process GO:0031329 52 24 3,000 1,194E-05 7,766E-04 ! regulation of oxidoreductase activity GO:0051341 46 24 3,000 1,194E-05 7,561E-04 ! vasculogenesis GO:0001570 46 25 3,000 1,415E-05 8,73E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,665E-05 1,001E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 1,718E-05 1,008E-03 ! regulation of glycolysis GO:0006110 21 9 2,000 1,718E-05 9,84E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,718E-05 9,611E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,443E-05 1,336E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 2,443E-05 1,306E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 2,443E-05 1,278E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 2,000 2,443E-05 1,251E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 3,019E-05 1,513E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 3,272E-05 1,607E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 3,344E-05 1,609E-03 ! oocyte differentiation GO:0009994 18 11 2,000 3,344E-05 1,578E-03 ! negative regulation of protein transport GO:0051224 69 33 3,000 4,41E-05 2,04E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,439E-05 2,015E-03 ! T cell homeostasis GO:0043029 25 12 2,000 4,439E-05 1,978E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,439E-05 1,942E-03 GO:0042130|negative regulation of T cell proliferation, ! actin filament organization GO:0007015 148 66 4,000 4,799E-05 2,062E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 5,161E-05 2,178E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 5,161E-05 2,141E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 5,544E-05 2,261E-03 ! embryonic placenta development GO:0001892 23 13 2,000 5,746E-05 2,304E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 2,000 5,746E-05 2,266E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 5,746E-05 2,23E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of DNA binding GO:0043392 68 37 3,000 6,986E-05 2,668E-03 ! regulation of protein stability GO:0031647 73 37 3,000 6,986E-05 2,626E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 6,986E-05 2,586E-03 ! response to gamma radiation GO:0010332 28 14 2,000 7,281E-05 2,654E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 7,299E-05 2,621E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 9,061E-05 3,206E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 9,061E-05 3,16E-03 ! lymphocyte homeostasis GO:0002260 30 15 2,000 9,061E-05 3,114E-03 ! negative regulation of binding GO:0051100 72 40 3,000 9,532E-05 3,23E-03 ! cytokinesis GO:0000910 72 40 3,000 9,532E-05 3,185E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 1,11E-04 3,659E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 1,11E-04 3,61E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 1,11E-04 3,562E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,11E-04 3,515E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 2,000 1,11E-04 3,469E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,157E-04 3,568E-03 ! myoblast differentiation GO:0045445 45 17 2,000 1,342E-04 4,088E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,342E-04 4,037E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,342E-04 3,987E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 1,342E-04 3,938E-03 ! response to nutrient GO:0007584 125 82 4,000 1,356E-04 3,932E-03 ! developmental growth GO:0048589 82 44 3,000 1,39E-04 3,981E-03 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 1,518E-04 4,298E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 1,604E-04 4,487E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,604E-04 4,435E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 1,604E-04 4,385E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,655E-04 4,475E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,655E-04 4,425E-03 ! tube morphogenesis GO:0035239 176 86 4,000 1,698E-04 4,49E-03 ! mitochondrion organization GO:0007005 148 86 4,000 1,698E-04 4,442E-03 ! endosome transport GO:0016197 108 47 3,000 1,801E-04 4,659E-03 ! regulation of DNA binding GO:0051101 155 88 4,000 1,892E-04 4,843E-03 ! gland development GO:0048732 206 88 4,000 1,892E-04 4,792E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 1,896E-04 4,752E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,955E-04 4,85E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,955E-04 4,801E-03 ! regulation of cell adhesion GO:0030155 212 89 4,000 1,995E-04 4,849E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 2,102E-04 5,058E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 2,221E-04 5,29E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine modification GO:0018209 43 20 2,000 2,221E-04 5,238E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,221E-04 5,188E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 2,451E-04 5,669E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,477E-04 5,675E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! female pregnancy GO:0007565 164 94 4,000 2,576E-04 5,847E-03 ! hindlimb morphogenesis GO:0035137 43 21 2,000 2,58E-04 5,8E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,58E-04 5,747E-03 ! cell aging GO:0007569 44 21 2,000 2,58E-04 5,694E-03 ! oogenesis GO:0048477 36 21 2,000 2,58E-04 5,642E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 2,000 2,58E-04 5,591E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 2,58E-04 5,541E-03 ! positive regulation of growth GO:0045927 90 52 3,000 2,67E-04 5,686E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 2,67E-04 5,636E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 2,974E-04 6,222E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,974E-04 6,168E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,974E-04 6,115E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 2,974E-04 6,063E-03 ! regulation of protein localization GO:0032880 176 97 4,000 2,981E-04 6,027E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 3,277E-04 6,57E-03 GO:0060538|skeletal muscle organ development, ! regulation of protein catabolic process GO:0042176 116 55 3,000 3,318E-04 6,597E-03 ! aging GO:0007568 103 55 3,000 3,318E-04 6,543E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 3,405E-04 6,66E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,405E-04 6,606E-03 ! sex determination GO:0007530 47 23 2,000 3,405E-04 6,554E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 3,511E-04 6,703E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,511E-04 6,651E-03 ! anagen GO:0042640 6 5 1,000 3,511E-04 6,599E-03 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 1,000 3,511E-04 6,548E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,511E-04 6,497E-03 ! microvillus organization GO:0032528 7 5 1,000 3,511E-04 6,448E-03 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 9 5 1,000 3,511E-04 6,399E-03 ! response to food GO:0032094 6 5 1,000 3,511E-04 6,351E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,511E-04 6,303E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 3,511E-04 6,257E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,511E-04 6,211E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,511E-04 6,165E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,511E-04 6,121E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,511E-04 6,077E-03 ! decidualization GO:0046697 11 5 1,000 3,511E-04 6,033E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 3,511E-04 5,99E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,511E-04 5,948E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 3,511E-04 5,907E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,511E-04 5,866E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,511E-04 5,825E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,511E-04 5,785E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,511E-04 5,746E-03 ! stem cell division GO:0017145 11 5 1,000 3,511E-04 5,707E-03 GO:0048103|somatic stem cell division, ! skeletal muscle fiber development GO:0048741 111 56 3,000 3,556E-04 5,742E-03 ! muscle fiber development GO:0048747 112 57 3,000 3,807E-04 6,106E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 3,807E-04 6,066E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,874E-04 6,132E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 3,874E-04 6,092E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 3,874E-04 6,053E-03 ! DNA catabolic process GO:0006308 86 59 3,000 4,346E-04 6,746E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 4,383E-04 6,76E-03 ! molting cycle process GO:0022404 50 26 2,000 4,933E-04 7,56E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 4,933E-04 7,512E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 4,933E-04 7,465E-03 ! blastocyst development GO:0001824 49 26 2,000 4,933E-04 7,418E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 5,245E-04 7,838E-03 ! male meiosis GO:0007140 7 6 1,000 5,245E-04 7,79E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 5,245E-04 7,742E-03 ! neuron remodeling GO:0016322 15 6 1,000 5,245E-04 7,695E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 5,245E-04 7,648E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 5,245E-04 7,602E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! activation of MAPKKK activity GO:0000185 12 6 1,000 5,245E-04 7,557E-03 ! neuron apoptosis GO:0051402 9 6 1,000 5,245E-04 7,512E-03 ! male sex determination GO:0030238 15 6 1,000 5,245E-04 7,467E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 5,245E-04 7,423E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! deoxyribonucleoside metabolic process GO:0009120 8 6 1,000 5,245E-04 7,38E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 5,245E-04 7,337E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 1,000 5,245E-04 7,295E-03 ! response to UV-C GO:0010225 11 6 1,000 5,245E-04 7,253E-03 ! regulation of dendrite development GO:0050773 16 6 1,000 5,245E-04 7,211E-03 ! hair follicle maturation GO:0048820 7 6 1,000 5,245E-04 7,17E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 5,245E-04 7,13E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 5,245E-04 7,09E-03 ! maternal placenta development GO:0001893 12 6 1,000 5,245E-04 7,05E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,245E-04 7,011E-03 ! gonad development GO:0008406 98 62 3,000 5,253E-04 6,983E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 5,253E-04 6,944E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 5,526E-04 7,265E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 5,526E-04 7,225E-03 ! male gonad development GO:0008584 44 27 2,000 5,526E-04 7,186E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,526E-04 7,148E-03 ! developmental maturation GO:0021700 116 66 3,000 6,662E-04 8,571E-03 ! response to organic cyclic substance GO:0014070 55 29 2,000 6,842E-04 8,757E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,842E-04 8,71E-03 ! tissue homeostasis GO:0001894 48 29 2,000 6,842E-04 8,665E-03 GO:0048871|multicellular organismal homeostasis, ! homeostasis of number of cells GO:0048872 114 67 3,000 7,052E-04 8,883E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,314E-04 9,166E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 7,314E-04 9,118E-03 ! mRNA stabilization GO:0048255 18 7 1,000 7,314E-04 9,071E-03 GO:0043489|RNA stabilization, ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 1,000 7,314E-04 9,025E-03 ! vesicle fusion GO:0006906 17 7 1,000 7,314E-04 8,979E-03 ! glycerol ether catabolic process GO:0044269 12 7 1,000 7,314E-04 8,933E-03 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 7,314E-04 8,888E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 7,314E-04 8,843E-03 ! spindle checkpoint GO:0031577 15 7 1,000 7,314E-04 8,799E-03 ! centrosome duplication GO:0051298 13 7 1,000 7,314E-04 8,755E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 7,314E-04 8,712E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 7,314E-04 8,669E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 7,314E-04 8,627E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,314E-04 8,584E-03 ! negative regulation of nuclear division GO:0051784 14 7 1,000 7,314E-04 8,543E-03 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 1,000 7,314E-04 8,502E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 7,314E-04 8,461E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 7,569E-04 8,714E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 7,569E-04 8,672E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 7,569E-04 8,631E-03 ! response to heat GO:0009408 50 30 2,000 7,569E-04 8,59E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 7,881E-04 8,902E-03 ! appendage morphogenesis GO:0035107 135 70 3,000 8,32E-04 9,354E-03 GO:0035108|limb morphogenesis, ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 8,344E-04 9,337E-03 GO:0043433|negative regulation of transcription factor activity, ! reproductive structure development GO:0048608 113 71 3,000 8,775E-04 9,775E-03 ! appendage development GO:0048736 136 71 3,000 8,775E-04 9,73E-03 GO:0060173|limb development, ! metanephros development GO:0001656 74 32 2,000 9,167E-04 0,01011682 ! response to ionizing radiation GO:0010212 65 32 2,000 9,167E-04 0,01007062 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 9,167E-04 0,01002485 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 9,714E-04 0,01057552 ! neutral lipid catabolic process GO:0046461 13 8 1,000 9,714E-04 0,01052789 ! T-helper 1 type immune response GO:0042088 12 8 1,000 9,714E-04 0,01048068 ! glycerolipid catabolic process GO:0046503 13 8 1,000 9,714E-04 0,01043389 ! hemoglobin metabolic process GO:0020027 13 8 1,000 9,714E-04 0,01038751 ! pigment granule organization GO:0048753 16 8 1,000 9,714E-04 0,01034155 ! regulation of pigmentation during development GO:0048070 24 8 1,000 9,714E-04 0,01029599 ! melanin metabolic process GO:0006582 15 8 1,000 9,714E-04 0,01025084 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 9,714E-04 0,01020607 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,714E-04 0,0101617 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 9,714E-04 0,01011771 ! regulation of vascular permeability GO:0043114 12 8 1,000 9,714E-04 0,0100741 ! response to UV-B GO:0010224 16 8 1,000 9,714E-04 0,01003086 ! blastocyst growth GO:0001832 19 8 1,000 9,714E-04 9,988E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 9,714E-04 9,945E-03 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,025E-03 0,01044844 GO:0090046|regulation of transcription regulator activity, ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 1,096E-03 0,01112899 ! development of primary sexual characteristics GO:0045137 124 76 3,000 1,132E-03 0,01144591 ! regulation of muscle development GO:0048634 70 35 2,000 1,194E-03 0,01201771 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,194E-03 0,01196764 ! negative regulation of cell adhesion GO:0007162 81 35 2,000 1,194E-03 0,01191798 ! female gonad development GO:0008585 58 35 2,000 1,194E-03 0,01186873 ! regulation of developmental growth GO:0048638 15 9 1,000 1,244E-03 0,0123175 ! Golgi to endosome transport GO:0006895 23 9 1,000 1,244E-03 0,01226702 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,244E-03 0,01221695 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,244E-03 0,01216728 ! T cell selection GO:0045058 23 9 1,000 1,244E-03 0,01211802 ! receptor clustering GO:0043113 18 9 1,000 1,244E-03 0,01206916 ! behavioral fear response GO:0001662 22 9 1,000 1,244E-03 0,01202069 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,244E-03 0,01197261 ! protein heterooligomerization GO:0051291 16 9 1,000 1,244E-03 0,01192491 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,244E-03 0,01187759 ! gas homeostasis GO:0033483 16 9 1,000 1,244E-03 0,01183064 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,244E-03 0,01178406 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,244E-03 0,01173785 ! response to steroid hormone stimulus GO:0048545 137 78 3,000 1,247E-03 0,01172194 ! maintenance of protein location in cell GO:0032507 86 36 2,000 1,297E-03 0,01213873 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 2,000 1,297E-03 0,01209168 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,297E-03 0,01204499 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,297E-03 0,01199867 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,308E-03 0,01205469 ! tissue remodeling GO:0048771 76 37 2,000 1,405E-03 0,01290109 ! regulation of neuron differentiation GO:0045664 167 81 3,000 1,435E-03 0,01312487 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,501E-03 0,01368228 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,519E-03 0,01378785 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,519E-03 0,01373602 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 2,000 1,519E-03 0,01368457 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 2,000 1,519E-03 0,01363351 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,549E-03 0,01385407 ! lung alveolus development GO:0048286 26 10 1,000 1,549E-03 0,01380276 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,549E-03 0,01375183 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,549E-03 0,01370127 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,549E-03 0,01365108 GO:0005978|glycogen biosynthetic process, ! B cell proliferation GO:0042100 18 10 1,000 1,549E-03 0,01360126 ! multicellular organism growth GO:0035264 18 10 1,000 1,549E-03 0,0135518 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 1,549E-03 0,0135027 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,549E-03 0,01345395 ! regulation of bone resorption GO:0045124 25 10 1,000 1,549E-03 0,01340556 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,549E-03 0,01335751 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,549E-03 0,01330981 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 1,000 1,549E-03 0,01326244 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,549E-03 0,01321541 ! blastocyst formation GO:0001825 17 10 1,000 1,549E-03 0,01316871 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 1,549E-03 0,01312234 ! response to nicotine GO:0035094 20 10 1,000 1,549E-03 0,0130763 ! localization within membrane GO:0051668 20 10 1,000 1,549E-03 0,01303058 ! mammary gland development GO:0030879 86 39 2,000 1,638E-03 0,01373164 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,638E-03 0,01368396 ! negative regulation of transport GO:0051051 153 84 3,000 1,641E-03 0,01366126 ! regulation of ligase activity GO:0051340 142 84 3,000 1,641E-03 0,01361415 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 1,763E-03 0,01457706 ! mesenchymal cell development GO:0014031 87 40 2,000 1,763E-03 0,01452714 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 2,000 1,763E-03 0,01447756 ! regulation of protein transport GO:0051223 154 87 3,000 1,867E-03 0,01527856 GO:0070201|regulation of establishment of protein localization, ! negative regulation of muscle development GO:0048635 20 11 1,000 1,886E-03 0,01537976 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,886E-03 0,01532781 ! blood vessel remodeling GO:0001974 29 11 1,000 1,886E-03 0,0152762 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,886E-03 0,01522493 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,886E-03 0,01517401 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 1,000 1,886E-03 0,01512343 ! adult heart development GO:0007512 14 11 1,000 1,886E-03 0,01507319 ! negative regulation of ossification GO:0030279 26 11 1,000 1,886E-03 0,01502328 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,886E-03 0,0149737 ! neuroblast proliferation GO:0007405 24 11 1,000 1,886E-03 0,01492444 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,886E-03 0,01487551 ! thymus development GO:0048538 27 11 1,000 1,886E-03 0,0148269 ! regulation of embryonic development GO:0045995 27 11 1,000 1,886E-03 0,0147786 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,894E-03 0,01479494 ! T cell differentiation GO:0030217 81 41 2,000 1,894E-03 0,01474706 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,894E-03 0,01469949 ! female gamete generation GO:0007292 61 41 2,000 1,894E-03 0,01465223 ! sex differentiation GO:0007548 145 90 3,000 2,114E-03 0,01629967 ! glucose transport GO:0015758 65 43 2,000 2,174E-03 0,01670768 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 2,174E-03 0,01665447 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 2,254E-03 0,01721611 ! virus-host interaction GO:0019048 29 12 1,000 2,254E-03 0,01716163 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,254E-03 0,01710749 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,254E-03 0,01705369 ! hippocampus development GO:0021766 26 12 1,000 2,254E-03 0,01700023 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,254E-03 0,01694711 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 2,254E-03 0,01689431 ! focal adhesion formation GO:0048041 35 12 1,000 2,254E-03 0,01684184 ! mitotic spindle organization GO:0007052 21 12 1,000 2,254E-03 0,0167897 ! fear response GO:0042596 26 12 1,000 2,254E-03 0,01673788 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 1,000 2,254E-03 0,01668638 ! histone acetylation GO:0016573 26 12 1,000 2,254E-03 0,0166352 ! gland morphogenesis GO:0022612 29 12 1,000 2,254E-03 0,01658432 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 2,254E-03 0,01653376 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,254E-03 0,01648351 ! spleen development GO:0048536 22 12 1,000 2,254E-03 0,01643356 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,254E-03 0,01638391 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,254E-03 0,01633456 ! hexose transport GO:0008645 67 44 2,000 2,322E-03 0,01677983 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 2,000 2,322E-03 0,01672959 ! maintenance of location in cell GO:0051651 97 44 2,000 2,322E-03 0,01667965 ! regulation of membrane potential GO:0042391 164 93 3,000 2,382E-03 0,01705701 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,477E-03 0,01768756 ! forebrain development GO:0030900 188 95 3,000 2,573E-03 0,01831839 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,639E-03 0,01872799 ! negative regulation of cell migration GO:0030336 115 46 2,000 2,639E-03 0,01867291 ! regulation of chemokine production GO:0032642 18 13 1,000 2,653E-03 0,01872127 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,653E-03 0,01866653 GO:0000725|recombinational repair, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 2,653E-03 0,0186121 ! organelle fusion GO:0048284 32 13 1,000 2,653E-03 0,018558 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,653E-03 0,01850421 ! response to X-ray GO:0010165 25 13 1,000 2,653E-03 0,01845073 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,653E-03 0,01839756 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,653E-03 0,01834469 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,653E-03 0,01829213 ! mitochondrial transport GO:0006839 82 48 2,000 2,98E-03 0,02048827 ! cellular component disassembly GO:0022411 86 48 2,000 2,98E-03 0,0204299 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,98E-03 0,02037186 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,083E-03 0,02101628 ! regulation of S phase GO:0033261 23 14 1,000 3,083E-03 0,02095692 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,083E-03 0,02089788 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,083E-03 0,02083918 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,083E-03 0,02078081 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,083E-03 0,02072276 GO:0060675|ureteric bud morphogenesis, ! bone mineralization GO:0030282 17 14 1,000 3,083E-03 0,02066504 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 3,083E-03 0,02060763 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 3,083E-03 0,02055055 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,083E-03 0,02049378 ! regulation of RNA stability GO:0043487 32 14 1,000 3,083E-03 0,02043732 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,083E-03 0,02038118 ! response to temperature stimulus GO:0009266 76 49 2,000 3,161E-03 0,02083646 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,348E-03 0,02200967 ! vesicle organization GO:0016050 107 51 2,000 3,542E-03 0,02322009 ! regulation of cell shape GO:0008360 125 51 2,000 3,542E-03 0,02315699 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 3,542E-03 0,02309423 ! response to estrogen stimulus GO:0043627 93 51 2,000 3,542E-03 0,02303181 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,544E-03 0,02298263 ! pituitary gland development GO:0021983 29 15 1,000 3,544E-03 0,02292084 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,544E-03 0,02285939 ! muscle maintenance GO:0046716 26 15 1,000 3,544E-03 0,02279827 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 3,544E-03 0,02273748 ! regulation of angiogenesis GO:0045765 114 52 2,000 3,742E-03 0,02394727 ! cartilage development GO:0051216 90 52 2,000 3,742E-03 0,02388375 ! cell maturation GO:0048469 100 53 2,000 3,95E-03 0,02514 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 4,034E-03 0,02561074 ! activation of MAPKK activity GO:0000186 35 16 1,000 4,034E-03 0,02554334 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,034E-03 0,0254763 ! neuron recognition GO:0008038 35 16 1,000 4,034E-03 0,02540961 ! biomineral formation GO:0031214 20 16 1,000 4,034E-03 0,02534327 ! heart morphogenesis GO:0003007 97 55 2,000 4,385E-03 0,02747421 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 4,385E-03 0,02740285 ! negative regulation of cell motion GO:0051271 134 55 2,000 4,385E-03 0,02733185 ! metencephalon development GO:0022037 30 17 1,000 4,554E-03 0,02831423 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,554E-03 0,02824125 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 1,000 4,554E-03 0,02816865 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 41 17 1,000 4,554E-03 0,02809643 ! limbic system development GO:0021761 36 17 1,000 4,554E-03 0,02802457 ! heart looping GO:0001947 30 17 1,000 4,554E-03 0,02795308 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,554E-03 0,02788195 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,554E-03 0,02781118 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,554E-03 0,02774078 ! regulation of protein binding GO:0043393 33 17 1,000 4,554E-03 0,02767072 ! neural crest cell migration GO:0001755 37 17 1,000 4,554E-03 0,02760102 ! nucleotide-excision repair GO:0006289 83 56 2,000 4,613E-03 0,02788653 ! regulation of DNA replication GO:0006275 101 56 2,000 4,613E-03 0,02781664 ! regulation of bone remodeling GO:0046850 137 57 2,000 4,848E-03 0,02916139 ! maintenance of location GO:0051235 118 57 2,000 4,848E-03 0,02908867 ! regulation of tissue remodeling GO:0034103 140 58 2,000 5,09E-03 0,03046615 ! neuron maturation GO:0042551 42 18 1,000 5,104E-03 0,03046917 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,104E-03 0,03039375 ! centrosome cycle GO:0007098 25 18 1,000 5,104E-03 0,03031871 ! positive regulation of proteolysis GO:0045862 31 18 1,000 5,104E-03 0,03024403 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,104E-03 0,03016972 ! cell-substrate junction assembly GO:0007044 54 18 1,000 5,104E-03 0,03009578 ! kidney development GO:0001822 122 60 2,000 5,596E-03 0,03292172 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 5,682E-03 0,03334148 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 5,682E-03 0,03326035 ! lipid phosphorylation GO:0046834 35 19 1,000 5,682E-03 0,03317962 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,682E-03 0,03309929 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,682E-03 0,03301934 ! neuromuscular junction development GO:0007528 34 19 1,000 5,682E-03 0,03293977 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,682E-03 0,03286059 ! protein export from nucleus GO:0006611 36 19 1,000 5,682E-03 0,03278179 ! cellular pigmentation GO:0033059 36 19 1,000 5,682E-03 0,03270336 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,682E-03 0,03262531 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,288E-03 0,03602268 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,288E-03 0,03593711 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,288E-03 0,03585196 ! response to alkaloid GO:0043279 38 20 1,000 6,288E-03 0,0357672 ! D-ribose metabolic process GO:0006014 29 20 1,000 6,288E-03 0,03568284 ! ribosomal small subunit biogenesis GO:0042274 24 20 1,000 6,288E-03 0,03559888 ! diencephalon development GO:0021536 34 20 1,000 6,288E-03 0,03551532 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 1,000 6,288E-03 0,03543214 ! actin filament-based movement GO:0030048 43 20 1,000 6,288E-03 0,03534936 ! negative regulation of translation GO:0017148 29 20 1,000 6,288E-03 0,03526696 ! regulation of mitosis GO:0007088 105 63 2,000 6,41E-03 0,03586783 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 6,41E-03 0,03578461 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 6,696E-03 0,03729523 ! multicellular organism reproduction GO:0032504 111 64 2,000 6,696E-03 0,0372091 GO:0048609|reproductive process in a multicellular organism, ! axis specification GO:0009798 38 21 1,000 6,923E-03 0,03837967 ! ovarian follicle development GO:0001541 35 21 1,000 6,923E-03 0,03829144 ! positive regulation of locomotion GO:0040017 39 21 1,000 6,923E-03 0,03820361 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 1,000 6,923E-03 0,03811619 ! response to cytokine stimulus GO:0034097 63 21 1,000 6,923E-03 0,03802917 ! gut development GO:0048565 39 21 1,000 6,923E-03 0,03794254 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 6,99E-03 0,03822258 GO:0035113|embryonic appendage morphogenesis, ! regulation of chemotaxis GO:0050920 40 22 1,000 7,586E-03 0,04138527 ! regeneration GO:0031099 41 22 1,000 7,586E-03 0,04129164 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 7,586E-03 0,04119843 ! deoxyribonucleotide metabolic process GO:0009262 32 22 1,000 7,586E-03 0,04110564 ! ureteric bud development GO:0001657 43 22 1,000 7,586E-03 0,04101327 ! renal system process GO:0003014 41 22 1,000 7,586E-03 0,04092131 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,586E-03 0,04082976 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,586E-03 0,04073863 ! activation of JUN kinase activity GO:0007257 42 22 1,000 7,586E-03 0,04064789 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 7,586E-03 0,04055757 ! protein stabilization GO:0050821 39 22 1,000 7,586E-03 0,04046764 ! activation of MAPK activity GO:0000187 115 67 2,000 7,6E-03 0,04045405 ! lung development GO:0030324 144 67 2,000 7,6E-03 0,04036475 ! negative regulation of ligase activity GO:0051352 112 68 2,000 7,916E-03 0,0419523 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 7,916E-03 0,0418601 ! urogenital system development GO:0001655 137 69 2,000 8,24E-03 0,04347786 ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,276E-03 0,04356907 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,276E-03 0,04347394 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 8,276E-03 0,04337923 ! response to ethanol GO:0045471 46 23 1,000 8,276E-03 0,04328493 ! regulation of viral reproduction GO:0050792 38 23 1,000 8,276E-03 0,04319103 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 1,000 8,276E-03 0,04309755 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,276E-03 0,04300446 ! respiratory tube development GO:0030323 150 70 2,000 8,572E-03 0,04444829 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 8,993E-03 0,04652994 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,993E-03 0,04643009 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 8,993E-03 0,04633067 ! multicellular organismal response to stress GO:0033555 49 24 1,000 8,993E-03 0,04623168 ! regulation of behavior GO:0050795 43 24 1,000 8,993E-03 0,0461331 ! lymphocyte proliferation GO:0046651 48 24 1,000 8,993E-03 0,04603495 ! pallium development GO:0021543 49 24 1,000 8,993E-03 0,04593721 ! pentose metabolic process GO:0019321 35 24 1,000 8,993E-03 0,04583988 ! protein tetramerization GO:0051262 52 24 1,000 8,993E-03 0,04574297 ! carbohydrate transport GO:0008643 110 72 2,000 9,259E-03 0,04699619 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 9,259E-03 0,04689725 ! respiratory system development GO:0060541 153 72 2,000 9,259E-03 0,04679873 ! learning or memory GO:0007611 147 73 2,000 9,614E-03 0,04849153 ! myelination GO:0042552 45 25 1,000 9,737E-03 0,04900868 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 9,737E-03 0,04890636 ! negative regulation of DNA replication GO:0008156 42 25 1,000 9,737E-03 0,04880448 ! receptor metabolic process GO:0043112 46 25 1,000 9,737E-03 0,04870301 ! neural crest cell development GO:0014032 54 25 1,000 9,737E-03 0,04860197 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 9,737E-03 0,04850134 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 9,737E-03 0,04840113 ! somitogenesis GO:0001756 43 25 1,000 9,737E-03 0,04830134 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,737E-03 0,04820195 ! neural tube closure GO:0001843 49 25 1,000 9,737E-03 0,04810297 GO:0060606|tube closure, ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01034735 0,05101584 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 0,01050682 0,05169615 ! tube lumen formation GO:0035148 50 26 1,000 0,01050682 0,05159065 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01050682 0,05148557 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01050682 0,05138093 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01050682 0,05127671 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01050682 0,05117291 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 0,01050682 0,05106953 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01130316 0,05482947 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01130316 0,05471914 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01130316 0,05460927 ! response to toxin GO:0009636 47 27 1,000 0,01130316 0,05449983 ! primary neural tube formation GO:0014020 51 27 1,000 0,01130316 0,05439083 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01130316 0,05428227 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,01150732 0,05515263 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01212524 0,05799868 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01212524 0,0578836 ! response to metal ion GO:0010038 140 80 2,000 0,01232058 0,05869965 ! muscle cell differentiation GO:0042692 159 80 2,000 0,01232058 0,05858364 ! T cell activation GO:0042110 168 81 2,000 0,01273927 0,060455 ! translational initiation GO:0006413 65 29 1,000 0,01297273 0,06144169 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01297273 0,06132098 ! cell fate determination GO:0001709 60 29 1,000 0,01297273 0,06120074 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01297273 0,06108097 ! response to drug GO:0042493 143 82 2,000 0,01316603 0,06187006 ! cell junction assembly GO:0034329 78 30 1,000 0,01384528 0,06493518 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01384528 0,06480885 GO:0008366|axon ensheathment, ! collagen metabolic process GO:0032963 45 31 1,000 0,01474259 0,06887507 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01474259 0,06874159 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01474259 0,06860863 ! ovulation cycle process GO:0022602 49 31 1,000 0,01474259 0,06847618 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01474259 0,06834424 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01474259 0,06821281 ! response to inorganic substance GO:0010035 153 86 2,000 0,01495417 0,06905898 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01566432 0,07219989 ! spindle organization GO:0007051 46 32 1,000 0,01566432 0,07206184 ! ovulation cycle GO:0042698 51 32 1,000 0,01566432 0,07192432 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01566432 0,07178732 ! hindbrain development GO:0030902 61 32 1,000 0,01566432 0,07165084 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01638092 0,0747865 ! post-embryonic development GO:0009791 69 33 1,000 0,01661015 0,07568942 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01661015 0,07554634 ! ossification GO:0001503 188 90 2,000 0,01687289 0,07659656 ! bone development GO:0060348 189 91 2,000 0,01737308 0,0787187 ! glial cell differentiation GO:0010001 63 34 1,000 0,01757977 0,07950549 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01757977 0,07935632 ! spermatid development GO:0007286 63 34 1,000 0,01757977 0,07920771 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 0,01757977 0,07905966 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01757977 0,07891216 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01839814 0,08243191 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01857286 0,08306002 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01857286 0,08290592 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01857286 0,08275239 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 1,000 0,01857286 0,08259943 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01857286 0,08244704 ! cytokine production GO:0001816 59 35 1,000 0,01857286 0,0822952 ! neural tube formation GO:0001841 67 35 1,000 0,01857286 0,08214392 ! transcription initiation GO:0006352 153 94 2,000 0,01892303 0,08353912 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01892303 0,08338612 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01958911 0,08616342 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01958911 0,08600619 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 0,01958911 0,08584953 ! cell junction organization GO:0034330 86 36 1,000 0,01958911 0,08569344 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01958911 0,08553791 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01958911 0,08538295 ! embryonic organ development GO:0048568 57 36 1,000 0,01958911 0,08522855 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01999757 0,08684865 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,02054722 0,08907499 ! protein ubiquitination GO:0016567 217 97 2,000 0,02054722 0,08891478 ! RNA export from nucleus GO:0006405 56 37 1,000 0,02062821 0,08910496 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,02062821 0,08894528 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 0,02062821 0,08878616 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02062821 0,08862761 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,02062821 0,08846963 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02062821 0,08831221 ! pigment metabolic process GO:0042440 80 37 1,000 0,02062821 0,08815535 ! spermatid differentiation GO:0048515 66 37 1,000 0,02062821 0,08799905 ! response to virus GO:0009615 160 98 2,000 0,02110514 0,08987427 ! Golgi vesicle transport GO:0048193 207 99 2,000 0,02167132 0,09212226 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02168985 0,09203841 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,02168985 0,09187637 ! lipid homeostasis GO:0055088 67 38 1,000 0,02168985 0,0917149 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02168985 0,091554 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02168985 0,09139366 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02168985 0,09123388 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,02168985 0,09107466 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,02277374 0,09545925 ! organic ether metabolic process GO:0018904 55 39 1,000 0,02277374 0,09529323 ! segmentation GO:0035282 67 39 1,000 0,02277374 0,09512779 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02277374 0,09496292 ! gliogenesis GO:0042063 88 41 1,000 0,02500703 0,104095 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02500703 0,10391521 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02615584 0,10850165 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02615584 0,1083149 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02615584 0,10812879 ! neuron migration GO:0001764 79 42 1,000 0,02615584 0,10794332 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02615584 0,10775848 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02732571 0,11238574 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,02732571 0,11219396 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02732571 0,11200283 ! neural tube development GO:0021915 77 43 1,000 0,02732571 0,11181235 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02851634 0,11648612 ! double-strand break repair GO:0006302 81 44 1,000 0,02851634 0,11628869 ! B cell differentiation GO:0030183 107 44 1,000 0,02851634 0,11609192 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02953031 0,12001678 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02953031 0,11981439 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02953031 0,11961268 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02953031 0,11941165 ! neuron fate determination GO:0048664 7 5 0,000 0,02953031 0,11921129 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02953031 0,11901161 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02953031 0,11881259 ! polyol transport GO:0015791 12 5 0,000 0,02953031 0,11861424 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02953031 0,11841655 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02953031 0,11821952 ! response to superoxide GO:0000303 10 5 0,000 0,02953031 0,11802314 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02953031 0,11782742 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02953031 0,11763234 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02953031 0,1174379 ! female meiosis GO:0007143 7 5 0,000 0,02953031 0,11724411 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02953031 0,11705096 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02953031 0,11685844 ! cobalt ion transport GO:0006824 11 5 0,000 0,02953031 0,11666655 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02953031 0,1164753 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02953031 0,11628467 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02953031 0,11609466 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02953031 0,11590527 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02953031 0,1157165 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02953031 0,11552834 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02953031 0,1153408 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02953031 0,11515386 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02953031 0,11496753 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02953031 0,1147818 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02953031 0,11459666 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02953031 0,11441213 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02953031 0,11422819 ! negative chemotaxis GO:0050919 14 5 0,000 0,02953031 0,11404483 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02953031 0,11386207 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02953031 0,11367989 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02953031 0,11349829 ! behavioral response to pain GO:0048266 9 5 0,000 0,02953031 0,11331728 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02953031 0,11313683 ! Notch receptor processing GO:0007220 8 5 0,000 0,02953031 0,11295697 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02953031 0,11277767 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02953031 0,11259894 ! micturition GO:0060073 9 5 0,000 0,02953031 0,11242078 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02953031 0,11224318 ! copulation GO:0007620 9 5 0,000 0,02953031 0,11206614 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02953031 0,11188966 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02953031 0,11171373 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02953031 0,11153835 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02953031 0,11136353 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02953031 0,11118925 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02953031 0,11101552 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02953031 0,11084233 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02953031 0,11066968 ! grooming behavior GO:0007625 6 5 0,000 0,02953031 0,11049756 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02953031 0,11032598 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02953031 0,11015493 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02953031 0,10998441 ! response to protozoan GO:0001562 10 5 0,000 0,02953031 0,10981442 ! lymph vessel development GO:0001945 10 5 0,000 0,02953031 0,10964496 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02953031 0,10947601 ! endochondral ossification GO:0001958 16 5 0,000 0,02953031 0,10930759 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02953031 0,10913968 ! parathyroid gland development GO:0060017 13 5 0,000 0,02953031 0,10897229 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02953031 0,10880541 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02953031 0,10863904 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02953031 0,10847318 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02953031 0,10830782 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02953031 0,10814297 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02953031 0,10797862 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02953031 0,10781477 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02953031 0,10765141 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02953031 0,10748855 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02953031 0,10732618 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02953031 0,1071643 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02953031 0,10700291 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02953031 0,106842 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02953031 0,10668158 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02953031 0,10652164 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02953031 0,10636217 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02953031 0,10620319 ! histidine catabolic process GO:0006548 6 5 0,000 0,02953031 0,10604467 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02953031 0,10588663 ! valine metabolic process GO:0006573 10 5 0,000 0,02953031 0,10572906 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02953031 0,10557196 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02953031 0,10541533 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02953031 0,10525916 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02953031 0,10510345 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02953031 0,1049482 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02953031 0,10479341 ! polyol catabolic process GO:0046174 7 5 0,000 0,02953031 0,10463907 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02953031 0,10448519 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02953031 0,10433176 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02953031 0,10417879 ! muscle cell migration GO:0014812 8 5 0,000 0,02953031 0,10402625 ! mitochondrial fission GO:0000266 8 5 0,000 0,02953031 0,10387417 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02953031 0,10372253 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02953031 0,10357133 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02953031 0,10342057 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02953031 0,10327025 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02953031 0,10312037 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02953031 0,10297092 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02953031 0,1028219 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02953031 0,10267331 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02953031 0,10252515 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02953031 0,10237742 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02953031 0,10223012 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02953031 0,10208324 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02953031 0,10193677 ! forebrain neuron development GO:0021884 13 5 0,000 0,02953031 0,10179073 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02953031 0,10164511 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02953031 0,1014999 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02953031 0,10135511 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02953031 0,10121073 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02953031 0,10106676 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02953031 0,1009232 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02953031 0,10078004 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02953031 0,1006373 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02953031 0,10049495 ! basic amino acid transport GO:0015802 11 5 0,000 0,02953031 0,10035301 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02953031 0,10021147 ! depyrimidination GO:0045008 10 5 0,000 0,02953031 0,10007033 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02953031 0,09992958 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02953031 0,09978923 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02953031 0,09964927 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02953031 0,09950971 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02953031 0,09937053 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02953031 0,09923175 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02953031 0,09909335 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02953031 0,09895534 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02953031 0,09881771 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02953031 0,09868046 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02953031 0,09854359 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02953031 0,09840711 ! response to arsenic GO:0046685 10 5 0,000 0,02953031 0,098271 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02953031 0,09813526 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02953031 0,09799991 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02953031 0,09786492 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02953031 0,0977303 ! response to cadmium ion GO:0046686 7 5 0,000 0,02953031 0,09759606 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02953031 0,09746218 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02953031 0,09732867 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02953031 0,09719553 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02953031 0,09706275 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02953031 0,09693033 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02953031 0,09679827 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02953031 0,09666657 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02953031 0,09653523 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02953031 0,09640425 ! neural tube patterning GO:0021532 7 5 0,000 0,02953031 0,09627362 ! embryonic cleavage GO:0040016 6 5 0,000 0,02953031 0,09614334 ! peroxisome fission GO:0016559 5 5 0,000 0,02953031 0,09601342 ! histone demethylation GO:0016577 10 5 0,000 0,02953031 0,09588385 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02953031 0,09575462 ! mitotic recombination GO:0006312 9 5 0,000 0,02953031 0,09562575 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02953031 0,09549722 ! metaphase plate congression GO:0051310 7 5 0,000 0,02953031 0,09536904 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02953031 0,0952412 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02953031 0,0951137 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02953031 0,09498654 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02953031 0,09485972 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02953031 0,09473324 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02953031 0,0946071 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02953031 0,09448129 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02953031 0,09435582 ! plasminogen activation GO:0031639 5 5 0,000 0,02953031 0,09423068 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02953031 0,09410587 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02953031 0,09398139 ! metaphase GO:0051323 8 5 0,000 0,02953031 0,09385724 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02953031 0,09373342 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02953031 0,09360992 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02953031 0,09348675 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02953031 0,0933639 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02953031 0,09324138 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02953031 0,09311918 ! response to redox state GO:0051775 5 5 0,000 0,02953031 0,09299729 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02953031 0,09287573 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02953031 0,09275448 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02953031 0,09263355 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02953031 0,09251293 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02953031 0,09239263 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02953031 0,09227264 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02953031 0,09215296 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02953031 0,09203359 ! striatum development GO:0021756 9 5 0,000 0,02953031 0,09191453 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02953031 0,09179578 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02953031 0,09167733 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02953031 0,09155919 ! glial cell migration GO:0008347 11 5 0,000 0,02953031 0,09144135 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02953031 0,09132382 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02953031 0,09120659 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02953031 0,09108966 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02953031 0,09097302 ! neuroprotection GO:0043526 6 5 0,000 0,02953031 0,09085669 ! neural plate development GO:0001840 8 5 0,000 0,02953031 0,09074065 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02953031 0,09062491 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02953031 0,09050947 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02953031 0,09039432 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02953031 0,09027946 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02953031 0,09016489 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02953031 0,09005061 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02953031 0,08993662 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02953031 0,08982292 ! spindle assembly GO:0051225 6 5 0,000 0,02953031 0,08970951 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02953031 0,08959638 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02953031 0,08948354 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02953031 0,08937098 ! drug metabolic process GO:0017144 6 5 0,000 0,02953031 0,08925871 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02953031 0,08914671 ! organ regeneration GO:0031100 7 5 0,000 0,02953031 0,089035 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02953031 0,08892357 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02953031 0,08881241 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02953031 0,08870154 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02972746 0,08918237 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 0,02972746 0,08907131 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! pigmentation GO:0043473 100 46 1,000 0,03095876 0,09264525 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03095876 0,09253017 ! positive regulation of defense response GO:0031349 76 47 1,000 0,03220998 0,09615039 ! response to calcium ion GO:0051592 81 47 1,000 0,03220998 0,09603124 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03220998 0,09591239 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03220998 0,09579383 ! JNK cascade GO:0007254 91 47 1,000 0,03220998 0,09567557 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,03220998 0,0955576 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03348083 0,09920552 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03348083 0,09908349 ! activation of caspase activity GO:0006919 84 48 1,000 0,03348083 0,09896177 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,03348083 0,09884034 ! regulation of action potential GO:0001508 95 49 1,000 0,03477104 0,10252343 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,03477104 0,10239794 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,03477104 0,10227276 ! endocrine system development GO:0035270 104 49 1,000 0,03477104 0,10214788 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,03477104 0,10202331 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03533147 0,10354144 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03533147 0,10341548 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03533147 0,10328982 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03533147 0,10316447 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03533147 0,10303942 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03533147 0,10291468 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03533147 0,10279023 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03533147 0,10266609 ! sleep GO:0030431 13 6 0,000 0,03533147 0,10254225 ! response to oxygen radical GO:0000305 11 6 0,000 0,03533147 0,1024187 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03533147 0,10229546 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03533147 0,1021725 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03533147 0,10204985 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03533147 0,10192749 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03533147 0,10180542 ! forebrain regionalization GO:0021871 8 6 0,000 0,03533147 0,10168364 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03533147 0,10156215 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03533147 0,10144096 ! response to zinc ion GO:0010043 9 6 0,000 0,03533147 0,10132005 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03533147 0,10119943 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03533147 0,1010791 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03533147 0,10095905 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03533147 0,10083929 ! malate metabolic process GO:0006108 11 6 0,000 0,03533147 0,10071981 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03533147 0,10060062 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03533147 0,10048171 ! protein refolding GO:0042026 15 6 0,000 0,03533147 0,10036307 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03533147 0,10024472 ! opsonization GO:0008228 8 6 0,000 0,03533147 0,10012665 ! mating behavior GO:0007617 7 6 0,000 0,03533147 0,10000885 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03533147 0,09989133 ! equilibrioception GO:0050957 14 6 0,000 0,03533147 0,09977409 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03533147 0,09965712 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03533147 0,09954043 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03533147 0,099424 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03533147 0,09930785 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03533147 0,09919198 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03533147 0,09907637 ! toxin metabolic process GO:0009404 11 6 0,000 0,03533147 0,09896103 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03533147 0,09884596 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03533147 0,09873115 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03533147 0,09861662 ! nuclear migration GO:0007097 12 6 0,000 0,03533147 0,09850234 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03533147 0,09838834 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03533147 0,09827459 ! thymic T cell selection GO:0045061 12 6 0,000 0,03533147 0,09816111 ! protein lipoylation GO:0009249 10 6 0,000 0,03533147 0,09804789 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03533147 0,09793494 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03533147 0,09782224 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03533147 0,0977098 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03533147 0,09759762 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03533147 0,09748569 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03533147 0,09737402 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03533147 0,09726261 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03533147 0,09715146 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03533147 0,09704055 ! hyperosmotic response GO:0006972 9 6 0,000 0,03533147 0,0969299 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03533147 0,0968195 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03533147 0,09670936 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03533147 0,09659946 ! urea metabolic process GO:0019627 7 6 0,000 0,03533147 0,09648981 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03533147 0,09638041 ! neutrophil activation GO:0042119 8 6 0,000 0,03533147 0,09627126 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03533147 0,09616236 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03533147 0,0960537 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03533147 0,09594529 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03533147 0,09583712 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03533147 0,09572919 ! nucleoside salvage GO:0043174 9 6 0,000 0,03533147 0,09562151 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03533147 0,09551407 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03533147 0,09540687 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03533147 0,09529991 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03533147 0,0951932 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03533147 0,09508672 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03533147 0,09498047 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03533147 0,09487447 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03533147 0,0947687 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03533147 0,09466317 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03533147 0,09455787 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03533147 0,0944528 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03533147 0,09434797 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03533147 0,09424337 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 0,000 0,03533147 0,09413901 ! astrocyte development GO:0014002 15 6 0,000 0,03533147 0,09403487 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03533147 0,09393097 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03533147 0,09382729 ! interaction with symbiont GO:0051702 13 6 0,000 0,03533147 0,09372384 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03533147 0,09362062 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03533147 0,09351763 ! response to copper ion GO:0046688 10 6 0,000 0,03533147 0,09341486 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03533147 0,09331232 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03533147 0,09321 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03533147 0,09310791 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03533147 0,09300604 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03533147 0,0929044 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03533147 0,09280297 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03533147 0,09270177 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03533147 0,09260079 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03533147 0,09250003 ! Schwann cell development GO:0014044 15 6 0,000 0,03533147 0,09239948 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03533147 0,09229916 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03533147 0,09219905 ! subpallium development GO:0021544 10 6 0,000 0,03533147 0,09209916 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03533147 0,09199948 ! histone ubiquitination GO:0016574 8 6 0,000 0,03533147 0,09190003 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03533147 0,09180078 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03533147 0,09170175 ! G2 phase GO:0051319 16 6 0,000 0,03533147 0,09160294 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03533147 0,09150433 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03533147 0,09140594 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03533147 0,09130776 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03533147 0,09120979 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03533147 0,09111203 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03533147 0,09101448 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03533147 0,09091714 ! receptor internalization GO:0031623 10 6 0,000 0,03533147 0,09082 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03533147 0,09072308 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03533147 0,09062636 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03533147 0,09052984 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03533147 0,09043354 ! protein deubiquitination GO:0016579 14 6 0,000 0,03533147 0,09033743 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03533147 0,09024153 ! protein destabilization GO:0031648 9 6 0,000 0,03533147 0,09014584 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03533147 0,09005034 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03533147 0,08995505 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03533147 0,08985996 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03533147 0,08976507 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03533147 0,08967038 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03533147 0,08957589 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03533147 0,0894816 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03533147 0,08938751 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03533147 0,08929362 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03533147 0,08919992 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03533147 0,08910642 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03533147 0,08901311 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03533147 0,08892 ! catecholamine transport GO:0051937 9 6 0,000 0,03533147 0,08882709 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03533147 0,08873437 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03533147 0,08864184 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03533147 0,0885495 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03533147 0,08845736 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03533147 0,08836541 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03533147 0,08827365 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03533147 0,08818208 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03533147 0,0880907 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03533147 0,08799951 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03533147 0,0879085 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,03608033 0,08967899 ! regulation of ossification GO:0030278 117 50 1,000 0,03608033 0,08958644 ! histone modification GO:0016570 91 50 1,000 0,03608033 0,08949409 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03608033 0,08940192 ! positive regulation of binding GO:0051099 78 51 1,000 0,03740843 0,0925974 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03740843 0,09250223 ! chromatin remodeling GO:0006338 109 51 1,000 0,03740843 0,09240726 ! membrane fusion GO:0006944 110 52 1,000 0,03875507 0,09563558 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03875507 0,09553759 ! synapse organization GO:0050808 85 52 1,000 0,03875507 0,09543981 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,04011998 0,09870008 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,04011998 0,09859927 ! tRNA transcription GO:0009304 14 7 0,000 0,04109815 0,10090015 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04109815 0,10079729 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04109815 0,10069465 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04109815 0,10059221 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04109815 0,10048998 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04109815 0,10038796 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04109815 0,10028615 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04109815 0,10018454 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04109815 0,10008314 ! prostate gland development GO:0030850 13 7 0,000 0,04109815 0,09998194 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04109815 0,09988095 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04109815 0,09978016 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04109815 0,09967958 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04109815 0,0995792 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04109815 0,09947902 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04109815 0,09937904 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04109815 0,09927926 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04109815 0,09917968 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04109815 0,0990803 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04109815 0,09898112 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04109815 0,09888214 ! glycolipid transport GO:0046836 10 7 0,000 0,04109815 0,09878336 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04109815 0,09868477 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04109815 0,09858638 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04109815 0,09848819 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04109815 0,09839019 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04109815 0,09829239 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04109815 0,09819478 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04109815 0,09809736 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04109815 0,09800014 ! pericardium development GO:0060039 14 7 0,000 0,04109815 0,09790311 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04109815 0,09780627 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04109815 0,09770963 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04109815 0,09761317 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04109815 0,09751691 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04109815 0,09742083 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04109815 0,09732494 ! lipoprotein transport GO:0042953 14 7 0,000 0,04109815 0,09722925 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04109815 0,09713374 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04109815 0,09703841 ! rhythmic behavior GO:0007622 15 7 0,000 0,04109815 0,09694328 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04109815 0,09684833 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04109815 0,09675356 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04109815 0,09665899 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04109815 0,09656459 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04109815 0,09647038 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04109815 0,09637636 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04109815 0,09628251 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04109815 0,09618885 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04109815 0,09609538 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04109815 0,09600208 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04109815 0,09590896 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04109815 0,09581603 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04109815 0,09572327 ! spinal cord patterning GO:0021511 13 7 0,000 0,04109815 0,0956307 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04109815 0,0955383 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04109815 0,09544608 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04109815 0,09535404 ! adrenal gland development GO:0030325 17 7 0,000 0,04109815 0,09526218 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04109815 0,09517049 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04109815 0,09507898 ! ovulation GO:0030728 9 7 0,000 0,04109815 0,09498765 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04109815 0,09489649 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04109815 0,09480551 ! microtubule nucleation GO:0007020 20 7 0,000 0,04109815 0,0947147 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04109815 0,09462406 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04109815 0,0945336 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04109815 0,09444331 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04109815 0,09435319 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04109815 0,09426324 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04109815 0,09417347 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04109815 0,09408387 ! galactose metabolic process GO:0006012 13 7 0,000 0,04109815 0,09399443 ! response to dietary excess GO:0002021 8 7 0,000 0,04109815 0,09390517 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04109815 0,09381607 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04109815 0,09372715 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,04109815 0,09363839 ! purine salvage GO:0043101 10 7 0,000 0,04109815 0,0935498 ! nucleoside transport GO:0015858 8 7 0,000 0,04109815 0,09346138 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04109815 0,09337313 ! parturition GO:0007567 14 7 0,000 0,04109815 0,09328504 ! rRNA modification GO:0000154 14 7 0,000 0,04109815 0,09319712 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04109815 0,09310936 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04109815 0,09302177 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04109815 0,09293434 ! macrophage differentiation GO:0030225 11 7 0,000 0,04109815 0,09284708 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04109815 0,09275998 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04109815 0,09267305 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04109815 0,09258628 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04109815 0,09249967 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04109815 0,09241322 ! fibrinolysis GO:0042730 10 7 0,000 0,04109815 0,09232693 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04109815 0,0922408 ! eating behavior GO:0042755 7 7 0,000 0,04109815 0,09215484 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04109815 0,09206903 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04109815 0,09198339 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04109815 0,0918979 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04109815 0,09181257 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04109815 0,0917274 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04109815 0,09164239 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04109815 0,09155754 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04109815 0,09147284 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04109815 0,0913883 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04109815 0,09130392 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04109815 0,09121969 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04109815 0,09113562 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04109815 0,0910517 ! regulation of meiosis GO:0040020 12 7 0,000 0,04109815 0,09096793 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04109815 0,09088432 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04109815 0,09080087 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04109815 0,09071756 ! transcription termination GO:0006353 13 7 0,000 0,04109815 0,09063441 ! response to tumor cell GO:0002347 13 7 0,000 0,04109815 0,09055141 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04109815 0,09046857 ! anaphase GO:0051322 17 7 0,000 0,04109815 0,09038587 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04109815 0,09030333 ! axonal fasciculation GO:0007413 18 7 0,000 0,04109815 0,09022093 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04109815 0,09013869 ! diuresis GO:0030146 12 7 0,000 0,04109815 0,0900566 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04109815 0,08997465 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04109815 0,08989286 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04109815 0,08981121 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04109815 0,08972971 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04109815 0,08964836 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04109815 0,08956716 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04109815 0,0894861 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04109815 0,08940519 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04109815 0,08932443 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04109815 0,08924381 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04109815 0,08916334 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04109815 0,08908301 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04109815 0,08900283 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04109815 0,08892279 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04109815 0,0888429 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04109815 0,08876314 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04109815 0,08868354 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04109815 0,08860407 ! adult feeding behavior GO:0008343 9 7 0,000 0,04109815 0,08852475 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04109815 0,08844557 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04109815 0,08836653 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04109815 0,08828763 ! muscle adaptation GO:0043500 14 7 0,000 0,04109815 0,08820887 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04109815 0,08813025 ! retina homeostasis GO:0001895 12 7 0,000 0,04109815 0,08805177 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04109815 0,08797344 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04109815 0,08789524 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04109815 0,08781718 ! protein prenylation GO:0018342 18 7 0,000 0,04109815 0,08773926 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04109815 0,08766147 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04109815 0,08758383 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04109815 0,08750632 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04150291 0,08829002 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,04150291 0,08821202 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04290359 0,0911086 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04290359 0,09102826 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,04290359 0,09094806 ! RNA elongation GO:0006354 79 55 1,000 0,04290359 0,090868 ! nuclear export GO:0051168 97 55 1,000 0,04290359 0,09078808 ! lipid modification GO:0030258 97 57 1,000 0,04575717 0,09674143 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04575717 0,0966565 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04683054 0,09883709 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04683054 0,09875046 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04683054 0,09866399 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04683054 0,09857767 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04683054 0,0984915 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04683054 0,09840548 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04683054 0,09831961 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04683054 0,0982339 ! meiotic prophase I GO:0007128 13 8 0,000 0,04683054 0,09814833 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04683054 0,09806291 ! oligopeptide transport GO:0006857 15 8 0,000 0,04683054 0,09797763 ! UTP metabolic process GO:0046051 8 8 0,000 0,04683054 0,09789251 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04683054 0,09780753 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04683054 0,0977227 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04683054 0,09763802 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04683054 0,09755349 ! succinate metabolic process GO:0006105 14 8 0,000 0,04683054 0,0974691 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04683054 0,09738486 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04683054 0,09730076 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04683054 0,09721681 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04683054 0,097133 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04683054 0,09704934 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04683054 0,09696582 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04683054 0,09688244 ! reflex GO:0060004 16 8 0,000 0,04683054 0,09679921 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04683054 0,09671612 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04683054 0,09663317 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04683054 0,09655037 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04683054 0,0964677 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04683054 0,09638518 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04683054 0,0963028 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04683054 0,09622056 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04683054 0,09613846 ! histidine metabolic process GO:0006547 16 8 0,000 0,04683054 0,0960565 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04683054 0,09597468 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04683054 0,095893 ! glycine catabolic process GO:0006546 13 8 0,000 0,04683054 0,09581146 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04683054 0,09573006 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04683054 0,09564879 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04683054 0,09556767 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04683054 0,09548668 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04683054 0,09540582 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04683054 0,09532511 ! macrophage activation GO:0042116 12 8 0,000 0,04683054 0,09524453 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04683054 0,09516409 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04683054 0,09508378 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04683054 0,09500361 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04683054 0,09492357 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04683054 0,09484367 ! osteoblast development GO:0002076 16 8 0,000 0,04683054 0,0947639 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04683054 0,09468427 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04683054 0,09460477 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04683054 0,0945254 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04683054 0,09444617 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04683054 0,09436707 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04683054 0,0942881 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04683054 0,09420926 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04683054 0,09413056 ! intermediate filament organization GO:0045109 12 8 0,000 0,04683054 0,09405199 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04683054 0,09397354 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04683054 0,09389523 ! cellular extravasation GO:0045123 12 8 0,000 0,04683054 0,09381705 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04683054 0,093739 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04683054 0,09366108 ! response to antibiotic GO:0046677 11 8 0,000 0,04683054 0,09358329 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04683054 0,09350563 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04683054 0,09342809 ! DNA topological change GO:0006265 12 8 0,000 0,04683054 0,09335069 ! response to tropane GO:0014073 15 8 0,000 0,04683054 0,09327341 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04683054 0,09319626 ! melanosome transport GO:0032402 13 8 0,000 0,04683054 0,09311924 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04683054 0,09304234 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04683054 0,09296558 ! mast cell activation GO:0045576 14 8 0,000 0,04683054 0,09288894 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04683054 0,09281242 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04683054 0,09273603 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04683054 0,09265977 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04683054 0,09258363 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04683054 0,09250762 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04683054 0,09243173 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04683054 0,09235597 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04683054 0,09228033 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04683054 0,09220481 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04683054 0,09212942 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04683054 0,09205415 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04683054 0,091979 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04683054 0,09190398 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04683054 0,09182908 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04683054 0,0917543 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04683054 0,09167964 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04683054 0,0916051 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04683054 0,09153069 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04683054 0,09145639 ! hormone catabolic process GO:0042447 17 8 0,000 0,04683054 0,09138222 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04683054 0,09130817 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04683054 0,09123423 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04683054 0,09116042 ! ATP catabolic process GO:0006200 11 8 0,000 0,04683054 0,09108672 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04683054 0,09101315 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04683054 0,09093969 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04683054 0,09086635 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04683054 0,09079313 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04683054 0,09072003 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04683054 0,09064705 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04683054 0,09057418 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04683054 0,09050143 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04683054 0,09042879 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04683054 0,09035628 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04683054 0,09028388 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04683054 0,09021159 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04683054 0,09013942 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04683054 0,09006737 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04683054 0,08999543 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04720956 0,09065139 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,05016427 0,09624818 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,05016427 0,09617149 ! camera-type eye development GO:0043010 116 60 1,000 0,05016427 0,09609492 ! axon extension GO:0048675 15 9 0,000 0,05252885 0,10054449 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05252885 0,10046456 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05252885 0,10038477 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05252885 0,10030509 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05252885 0,10022555 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05252885 0,10014613 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05252885 0,10006684 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05252885 0,09998767 ! phosphate transport GO:0006817 19 9 0,000 0,05252885 0,09990863 ! reproductive behavior GO:0019098 19 9 0,000 0,05252885 0,09982972 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05252885 0,09975092 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05252885 0,09967225 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05252885 0,09959371 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 0,000 0,05252885 0,09951529 ! RNA methylation GO:0001510 15 9 0,000 0,05252885 0,09943699 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05252885 0,09935882 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05252885 0,09928077 ! artery development GO:0060840 24 9 0,000 0,05252885 0,09920284 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05252885 0,09912503 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05252885 0,09904735 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05252885 0,09896979 ! chemosensory behavior GO:0007635 20 9 0,000 0,05252885 0,09889235 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05252885 0,09881503 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05252885 0,09873783 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05252885 0,09866075 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05252885 0,09858379 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05252885 0,09850695 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05252885 0,09843023 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05252885 0,09835363 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05252885 0,09827715 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05252885 0,09820079 ! protein targeting to ER GO:0045047 22 9 0,000 0,05252885 0,09812455 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05252885 0,09804842 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05252885 0,09797242 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05252885 0,09789653 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05252885 0,09782076 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05252885 0,0977451 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05252885 0,09766957 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05252885 0,09759415 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05252885 0,09751884 ! mannose metabolic process GO:0006013 13 9 0,000 0,05252885 0,09744365 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05252885 0,09736858 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05252885 0,09729363 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05252885 0,09721878 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05252885 0,09714406 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05252885 0,09706945 ! ruffle organization GO:0031529 15 9 0,000 0,05252885 0,09699495 ! retinol metabolic process GO:0042572 18 9 0,000 0,05252885 0,09692057 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05252885 0,0968463 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05252885 0,09677214 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05252885 0,0966981 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05252885 0,09662417 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05252885 0,09655036 ! segment specification GO:0007379 13 9 0,000 0,05252885 0,09647666 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05252885 0,09640307 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05252885 0,09632959 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05252885 0,09625622 ! response to amine stimulus GO:0014075 13 9 0,000 0,05252885 0,09618297 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05252885 0,09610982 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05252885 0,09603679 ! erythrocyte development GO:0048821 15 9 0,000 0,05252885 0,09596387 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05252885 0,09589106 ! renal water homeostasis GO:0003091 14 9 0,000 0,05252885 0,09581836 ! postreplication repair GO:0006301 22 9 0,000 0,05252885 0,09574577 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05252885 0,09567329 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05252885 0,09560092 ! icosanoid secretion GO:0032309 15 9 0,000 0,05252885 0,09552866 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05252885 0,09545651 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05252885 0,09538447 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05252885 0,09531253 ! regulation of cell division GO:0051302 15 9 0,000 0,05252885 0,09524071 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05252885 0,09516899 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05252885 0,09509738 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05252885 0,09502588 ! sterol catabolic process GO:0016127 11 9 0,000 0,05252885 0,09495448 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05252885 0,0948832 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05252885 0,09481202 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05252885 0,09474094 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05252885 0,09466998 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05252885 0,09459912 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05252885 0,09452836 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05252885 0,09445771 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05252885 0,09438717 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05252885 0,09431673 ! purine base metabolic process GO:0006144 21 9 0,000 0,05252885 0,0942464 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05252885 0,09417617 ! pigment granule transport GO:0051904 17 9 0,000 0,05252885 0,09410605 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05252885 0,09403603 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05252885 0,09396611 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05252885 0,0938963 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05252885 0,09382659 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05252885 0,09375699 ! mitochondrion localization GO:0051646 15 9 0,000 0,05252885 0,09368749 ! ear development GO:0043583 103 62 1,000 0,05318391 0,09478554 ! viral reproductive process GO:0022415 126 62 1,000 0,05318391 0,09471538 ! single fertilization GO:0007338 75 64 1,000 0,05626654 0,10013113 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05819329 0,10348341 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05819329 0,10340698 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05819329 0,10333066 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05819329 0,10325446 ! synapsis GO:0007129 13 10 0,000 0,05819329 0,10317837 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05819329 0,10310239 ! N-glycan processing GO:0006491 20 10 0,000 0,05819329 0,10302653 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05819329 0,10295077 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05819329 0,10287513 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05819329 0,1027996 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05819329 0,10272417 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05819329 0,10264886 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05819329 0,10257366 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05819329 0,10249857 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05819329 0,10242359 ! androgen metabolic process GO:0008209 17 10 0,000 0,05819329 0,10234872 ! phospholipid efflux GO:0033700 16 10 0,000 0,05819329 0,10227396 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05819329 0,10219931 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05819329 0,10212476 ! pathogenesis GO:0009405 13 10 0,000 0,05819329 0,10205033 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05819329 0,101976 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05819329 0,10190178 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05819329 0,10182767 ! endoderm development GO:0007492 16 10 0,000 0,05819329 0,10175367 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05819329 0,10167977 ! arginine catabolic process GO:0006527 13 10 0,000 0,05819329 0,10160599 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05819329 0,10153231 ! proline metabolic process GO:0006560 13 10 0,000 0,05819329 0,10145873 ! L-serine metabolic process GO:0006563 18 10 0,000 0,05819329 0,10138526 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05819329 0,1013119 ! V(D)J recombination GO:0033151 28 10 0,000 0,05819329 0,10123865 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05819329 0,1011655 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05819329 0,10109245 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05819329 0,10101952 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05819329 0,10094668 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05819329 0,10087396 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05819329 0,10080133 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05819329 0,10072881 ! epithelial cell development GO:0002064 20 10 0,000 0,05819329 0,1006564 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05819329 0,10058409 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05819329 0,10051188 ! macroautophagy GO:0016236 17 10 0,000 0,05819329 0,10043978 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05819329 0,10036778 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05819329 0,10029588 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05819329 0,10022409 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05819329 0,1001524 ! brain morphogenesis GO:0048854 23 10 0,000 0,05819329 0,10008081 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05819329 0,10000932 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05819329 0,09993794 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05819329 0,09986665 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05819329 0,09979547 ! response to dsRNA GO:0043331 20 10 0,000 0,05819329 0,09972439 ! DNA ligation GO:0006266 19 10 0,000 0,05819329 0,09965342 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05819329 0,09958254 ! melanosome localization GO:0032400 16 10 0,000 0,05819329 0,09951176 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05819329 0,09944109 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05819329 0,09937051 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05819329 0,09930004 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05819329 0,09922966 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05819329 0,09915938 ! mRNA cleavage GO:0006379 17 10 0,000 0,05819329 0,09908921 ! protein sumoylation GO:0016925 15 10 0,000 0,05819329 0,09901913 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05819329 0,09894915 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05819329 0,09887927 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05819329 0,09880949 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05819329 0,09873981 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05819329 0,09867023 ! salivary gland development GO:0007431 27 10 0,000 0,05819329 0,09860074 ! prophase GO:0051324 15 10 0,000 0,05819329 0,09853135 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05819329 0,09846206 ! apical protein localization GO:0045176 15 10 0,000 0,05819329 0,09839287 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05819329 0,09832377 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05819329 0,09825477 ! midbrain development GO:0030901 13 10 0,000 0,05819329 0,09818587 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05819329 0,09811706 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05819329 0,09804835 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05819329 0,09797974 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05819329 0,09791122 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05819329 0,0978428 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05819329 0,09777448 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05819329 0,09770625 ! detection of calcium ion GO:0005513 23 10 0,000 0,05819329 0,09763811 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05819329 0,09757007 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05819329 0,09750212 ! activation of innate immune response GO:0002218 12 10 0,000 0,05819329 0,09743427 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05819329 0,09736652 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05819329 0,09729885 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05819329 0,09723128 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05819329 0,09716381 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05941024 0,09912693 ! secondary metabolic process GO:0019748 116 66 1,000 0,05941024 0,09905823 ! cell projection assembly GO:0030031 120 66 1,000 0,05941024 0,09898963 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,0610044 0,1015755 ! chromosome segregation GO:0007059 113 67 1,000 0,0610044 0,10150525 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,0610044 0,1014351 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,0610044 0,10136505 ! adaptive immune response GO:0002250 119 67 1,000 0,0610044 0,1012951 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,06261314 0,10389463 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06261314 0,10382303 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,06261314 0,10375152 ! respiratory burst GO:0045730 17 11 0,000 0,06382404 0,10568524 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06382404 0,10561255 ! neuron fate specification GO:0048665 17 11 0,000 0,06382404 0,10553997 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06382404 0,10546748 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06382404 0,10539509 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,06382404 0,10532281 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06382404 0,10525062 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06382404 0,10517853 ! response to pain GO:0048265 24 11 0,000 0,06382404 0,10510654 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06382404 0,10503465 ! T cell proliferation GO:0042098 26 11 0,000 0,06382404 0,10496285 ! bone resorption GO:0045453 16 11 0,000 0,06382404 0,10489116 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06382404 0,10481956 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06382404 0,10474806 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06382404 0,10467665 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06382404 0,10460535 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06382404 0,10453414 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06382404 0,10446303 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06382404 0,10439201 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06382404 0,10432109 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06382404 0,10425027 ! lipid digestion GO:0044241 18 11 0,000 0,06382404 0,10417955 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06382404 0,10410892 ! UV protection GO:0009650 19 11 0,000 0,06382404 0,10403838 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06382404 0,10396794 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06382404 0,1038976 ! temperature homeostasis GO:0001659 17 11 0,000 0,06382404 0,10382735 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06382404 0,1037572 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06382404 0,10368714 ! regulation of organ growth GO:0046620 13 11 0,000 0,06382404 0,10361717 ! pigment granule localization GO:0051875 20 11 0,000 0,06382404 0,1035473 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06382404 0,10347753 ! vasoconstriction GO:0042310 18 11 0,000 0,06382404 0,10340785 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06382404 0,10333826 ! embryonic axis specification GO:0000578 18 11 0,000 0,06382404 0,10326876 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06382404 0,10319936 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06382404 0,10313005 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06382404 0,10306084 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06382404 0,10299172 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06382404 0,10292269 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06382404 0,10285375 ! zymogen activation GO:0031638 15 11 0,000 0,06382404 0,10278491 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06382404 0,10271615 ! nucleosome positioning GO:0016584 15 11 0,000 0,06382404 0,10264749 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06382404 0,10257893 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06382404 0,10251045 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06382404 0,10244206 ! acid secretion GO:0046717 18 11 0,000 0,06382404 0,10237377 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06382404 0,10230556 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06382404 0,10223745 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06382404 0,10216943 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06382404 0,1021015 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06382404 0,10203366 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06382404 0,1019659 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06382404 0,10189824 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06382404 0,10183067 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06382404 0,10176319 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06382404 0,1016958 ! embryonic gut development GO:0048566 15 11 0,000 0,06382404 0,10162849 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06382404 0,10156128 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06382404 0,10149415 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06382404 0,10142711 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06382404 0,10136017 ! defense response to fungus GO:0050832 13 11 0,000 0,06382404 0,10129331 ! developmental induction GO:0031128 19 11 0,000 0,06382404 0,10122653 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06382404 0,10115985 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06382404 0,10109325 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06382404 0,10102674 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06382404 0,10096032 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06382404 0,10089399 ! nucleus localization GO:0051647 19 11 0,000 0,06382404 0,10082774 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06382404 0,10076158 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06423621 0,10134579 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06423621 0,10127937 ! humoral immune response GO:0006959 109 71 1,000 0,06752447 0,10639415 ! B cell activation GO:0042113 160 71 1,000 0,06752447 0,10632452 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06752447 0,10625499 ! regulation of caspase activity GO:0043281 122 72 1,000 0,06918921 0,10880342 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06918921 0,10873236 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06918921 0,10866138 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06942132 0,1089548 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06942132 0,10888377 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06942132 0,10881284 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06942132 0,10874199 ! cartilage condensation GO:0001502 20 12 0,000 0,06942132 0,10867125 ! mating GO:0007618 17 12 0,000 0,06942132 0,10860059 ! protein complex disassembly GO:0043241 27 12 0,000 0,06942132 0,10853002 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06942132 0,10845955 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06942132 0,10838917 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06942132 0,10831887 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06942132 0,10824867 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06942132 0,10817856 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06942132 0,10810855 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06942132 0,10803862 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06942132 0,10796878 ! drug transport GO:0015893 16 12 0,000 0,06942132 0,10789903 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06942132 0,10782938 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06942132 0,10775981 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06942132 0,10769033 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06942132 0,10762094 ! forebrain cell migration GO:0021885 21 12 0,000 0,06942132 0,10755164 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06942132 0,10748244 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06942132 0,10741331 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06942132 0,10734428 ! entry into host cell GO:0030260 32 12 0,000 0,06942132 0,10727534 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,06942132 0,10720649 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06942132 0,10713772 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06942132 0,10706904 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06942132 0,10700045 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06942132 0,10693195 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06942132 0,10686353 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06942132 0,10679521 ! protein homotetramerization GO:0051289 21 12 0,000 0,06942132 0,10672697 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06942132 0,10665881 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06942132 0,10659075 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06942132 0,10652277 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06942132 0,10645488 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06942132 0,10638707 ! cranial nerve development GO:0021545 20 12 0,000 0,06942132 0,10631935 ! fucose catabolic process GO:0019317 22 12 0,000 0,06942132 0,10625172 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06942132 0,10618417 ! histone methylation GO:0016571 26 12 0,000 0,06942132 0,10611671 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06942132 0,10604934 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06942132 0,10598205 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06942132 0,10591484 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06942132 0,10584772 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06942132 0,10578069 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06942132 0,10571374 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06942132 0,10564687 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06942132 0,10558009 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06942132 0,10551339 ! response to cold GO:0009409 17 12 0,000 0,06942132 0,10544678 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06942132 0,10538025 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06942132 0,10531381 ! axon guidance GO:0007411 139 73 1,000 0,07086739 0,10743979 ! fertilization GO:0009566 90 73 1,000 0,07086739 0,10737213 ! meiosis GO:0007126 121 74 1,000 0,07255881 0,10986563 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,07255881 0,10979653 ! eye development GO:0001654 143 74 1,000 0,07255881 0,10972752 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07426323 0,1122345 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,07426323 0,11216405 ! meiotic cell cycle GO:0051321 122 75 1,000 0,07426323 0,11209368 ! rhythmic process GO:0048511 128 75 1,000 0,07426323 0,1120234 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07498532 0,11304178 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07498532 0,112971 ! peroxisomal transport GO:0043574 24 13 0,000 0,07498532 0,1129003 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07498532 0,1128297 ! lipid localization GO:0010876 28 13 0,000 0,07498532 0,11275918 GO:0019915|lipid storage, ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07498532 0,11268875 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07498532 0,1126184 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07498532 0,11254815 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07498532 0,11247798 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07498532 0,1124079 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07498532 0,11233791 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07498532 0,112268 ! methionine metabolic process GO:0006555 27 13 0,000 0,07498532 0,11219819 ! plasma membrane organization GO:0007009 24 13 0,000 0,07498532 0,11212845 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07498532 0,11205881 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07498532 0,11198925 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07498532 0,11191978 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07498532 0,11185039 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07498532 0,11178109 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07498532 0,11171188 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07498532 0,11164275 ! exocrine system development GO:0035272 32 13 0,000 0,07498532 0,11157371 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07498532 0,11150475 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07498532 0,11143588 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07498532 0,11136709 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07498532 0,11129839 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07498532 0,11122977 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07498532 0,11116123 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07498532 0,11109279 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07498532 0,11102442 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07498532 0,11095614 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07498532 0,11088794 ! ribosome assembly GO:0042255 17 13 0,000 0,07498532 0,11081983 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07498532 0,1107518 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07498532 0,11068385 ! chromatin silencing GO:0006342 26 13 0,000 0,07498532 0,11061599 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07498532 0,11054821 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07498532 0,11048052 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07498532 0,1104129 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07498532 0,11034537 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07498532 0,11027792 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07498532 0,11021056 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07498532 0,11014327 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07498532 0,11007607 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07498532 0,11000895 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07498532 0,10994192 ! insulin secretion GO:0030073 23 13 0,000 0,07498532 0,10987496 ! actin filament polymerization GO:0030041 24 13 0,000 0,07498532 0,10980808 ! acrosome reaction GO:0007340 18 13 0,000 0,07498532 0,10974129 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07771026 0,11366011 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07771026 0,11359105 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,07945244 0,11606713 ! protein oligomerization GO:0051259 139 78 1,000 0,07945244 0,1159967 ! rRNA transcription GO:0009303 25 14 0,000 0,08051624 0,11747851 ! lactation GO:0007595 26 14 0,000 0,08051624 0,11740731 ! reproductive cellular process GO:0048610 20 14 0,000 0,08051624 0,1173362 ! tRNA modification GO:0006400 20 14 0,000 0,08051624 0,11726517 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08051624 0,11719423 ! water transport GO:0006833 21 14 0,000 0,08051624 0,11712338 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08051624 0,11705261 ! non-recombinational repair GO:0000726 25 14 0,000 0,08051624 0,11698192 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08051624 0,11691132 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08051624 0,11684081 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08051624 0,11677038 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08051624 0,11670004 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08051624 0,11662978 ! palate development GO:0060021 31 14 0,000 0,08051624 0,1165596 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08051624 0,11648951 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08051624 0,11641951 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08051624 0,11634959 ! arginine metabolic process GO:0006525 17 14 0,000 0,08051624 0,11627975 ! regulation of heart rate GO:0002027 24 14 0,000 0,08051624 0,11621 ! organic alcohol transport GO:0015850 29 14 0,000 0,08051624 0,11614033 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08051624 0,11607074 ! embryo implantation GO:0007566 30 14 0,000 0,08051624 0,11600124 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08051624 0,11593182 ! L-amino acid transport GO:0015807 30 14 0,000 0,08051624 0,11586248 ! stem cell development GO:0048864 43 14 0,000 0,08051624 0,11579322 GO:0019827|stem cell maintenance, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08051624 0,11572405 ! cerebellum development GO:0021549 21 14 0,000 0,08051624 0,11565496 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08051624 0,11558596 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08051624 0,11551703 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08051624 0,11544819 ! cofactor transport GO:0051181 26 14 0,000 0,08051624 0,11537943 ! NADP metabolic process GO:0006739 24 14 0,000 0,08051624 0,11531075 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08051624 0,11524216 ! intestinal absorption GO:0050892 25 14 0,000 0,08051624 0,11517364 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08051624 0,11510521 ! oxygen transport GO:0015671 21 14 0,000 0,08051624 0,11503685 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08051624 0,11496858 ! male genitalia development GO:0030539 24 14 0,000 0,08051624 0,11490039 ! regulation of axon extension GO:0030516 37 14 0,000 0,08051624 0,11483228 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08051624 0,11476426 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,08120679 0,11568001 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,08120679 0,11561156 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,08120679 0,11554319 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,08120679 0,1154749 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,0829731 0,11791688 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,0829731 0,11784727 ! protein import into nucleus GO:0006606 158 80 1,000 0,0829731 0,11777775 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,08475117 0,12023073 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08475117 0,12015988 ! nuclear import GO:0051170 161 81 1,000 0,08475117 0,12008912 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08601426 0,12180713 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08601426 0,12173548 ! superoxide anion generation GO:0042554 20 15 0,000 0,08601426 0,12166391 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08601426 0,12159243 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08601426 0,12152103 ! copper ion transport GO:0006825 20 15 0,000 0,08601426 0,12144971 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08601426 0,12137848 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08601426 0,12130734 ! sulfate transport GO:0008272 23 15 0,000 0,08601426 0,12123627 ! response to cAMP GO:0051591 22 15 0,000 0,08601426 0,12116529 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08601426 0,12109439 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08601426 0,12102358 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08601426 0,12095284 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08601426 0,12088219 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08601426 0,12081163 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08601426 0,12074114 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08601426 0,12067074 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08601426 0,12060042 ! vesicle coating GO:0006901 33 15 0,000 0,08601426 0,12053018 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08601426 0,12046002 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08601426 0,12038994 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08601426 0,12031995 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08601426 0,12025004 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08601426 0,12018021 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08601426 0,12011045 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08601426 0,12004079 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08601426 0,1199712 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08601426 0,11990169 ! histone deacetylation GO:0016575 20 15 0,000 0,08601426 0,11983226 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08601426 0,11976291 ! tissue regeneration GO:0042246 26 15 0,000 0,08601426 0,11969365 ! water homeostasis GO:0030104 27 15 0,000 0,08601426 0,11962446 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08601426 0,11955535 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08601426 0,11948632 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08601426 0,11941738 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08601426 0,11934851 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08601426 0,11927972 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08601426 0,11921101 ! cell killing GO:0001906 29 15 0,000 0,08601426 0,11914238 ! detection of bacterium GO:0016045 18 15 0,000 0,08601426 0,11907383 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08601426 0,11900536 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08601426 0,11893696 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08601426 0,11886865 ! peptide hormone processing GO:0016486 23 15 0,000 0,08601426 0,11880041 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,0865408 0,11945908 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,0865408 0,11939058 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08834179 0,12180535 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,09015393 0,12423274 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,09015393 0,12416163 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09147959 0,12591528 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09147959 0,12584328 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09147959 0,12577137 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09147959 0,12569954 ! bone remodeling GO:0046849 27 16 0,000 0,09147959 0,1256278 ! filopodium assembly GO:0046847 32 16 0,000 0,09147959 0,12555613 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09147959 0,12548455 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09147959 0,12541305 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09147959 0,12534163 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09147959 0,12527029 ! startle response GO:0001964 28 16 0,000 0,09147959 0,12519903 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09147959 0,12512786 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09147959 0,12505676 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09147959 0,12498575 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09147959 0,12491481 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09147959 0,12484396 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09147959 0,12477319 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09147959 0,12470249 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09147959 0,12463188 ! response to osmotic stress GO:0006970 25 16 0,000 0,09147959 0,12456135 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09147959 0,1244909 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09147959 0,12442052 ! fructose metabolic process GO:0006000 25 16 0,000 0,09147959 0,12435023 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09147959 0,12428001 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09147959 0,12420988 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09147959 0,12413982 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09147959 0,12406984 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09147959 0,12399995 ! axon cargo transport GO:0008088 43 16 0,000 0,09147959 0,12393013 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09147959 0,12386038 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09147959 0,12379072 ! DNA replication initiation GO:0006270 27 16 0,000 0,09147959 0,12372114 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09147959 0,12365163 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09147959 0,1235822 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09147959 0,12351285 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09147959 0,12344358 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09147959 0,12337439 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09147959 0,12330527 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09147959 0,12323623 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09147959 0,12316727 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09147959 0,12309838 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09147959 0,12302957 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09197704 0,12362948 GO:0002696|positive regulation of leukocyte activation, ! oxidative phosphorylation GO:0006119 133 86 1,000 0,09381092 0,12602405 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09565537 0,12843015 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,09565537 0,12835852 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09691243 0,12997285 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09691243 0,12990044 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09691243 0,12982812 ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09691243 0,12975587 ! endothelial cell migration GO:0043542 28 17 0,000 0,09691243 0,1296837 ! inositol metabolic process GO:0006020 28 17 0,000 0,09691243 0,12961162 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09691243 0,12953961 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09691243 0,12946768 ! glial cell development GO:0021782 27 17 0,000 0,09691243 0,12939584 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09691243 0,12932407 ! adult walking behavior GO:0007628 33 17 0,000 0,09691243 0,12925238 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09691243 0,12918077 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09691243 0,12910925 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09691243 0,1290378 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09691243 0,12896643 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09691243 0,12889513 ! glycine metabolic process GO:0006544 28 17 0,000 0,09691243 0,12882392 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09691243 0,12875279 ! NAD metabolic process GO:0019674 29 17 0,000 0,09691243 0,12868173 ! membrane budding GO:0006900 37 17 0,000 0,09691243 0,12861075 ! DNA integration GO:0015074 29 17 0,000 0,09691243 0,12853985 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09691243 0,12846903 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09691243 0,12839829 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09691243 0,12832763 ! genitalia development GO:0048806 30 17 0,000 0,09691243 0,12825704 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09691243 0,12818653 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09691243 0,1281161 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09691243 0,12804574 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09691243 0,12797546 ! steroid catabolic process GO:0006706 31 17 0,000 0,09691243 0,12790526 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09691243 0,12783514 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09691243 0,12776509 ! gas transport GO:0015669 25 17 0,000 0,09691243 0,12769512 ! organic cation transport GO:0015695 31 17 0,000 0,09691243 0,12762523 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09691243 0,12755541 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09691243 0,12748567 ! microspike assembly GO:0030035 36 17 0,000 0,09691243 0,12741601 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09691243 0,12734642 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09691243 0,12727691 ! cellular respiration GO:0045333 135 88 1,000 0,09751022 0,12799213 ! regulation of neurological system process GO:0031644 148 88 1,000 0,09751022 0,12792235 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,10125031 0,13275654 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10231295 0,13407677 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10231295 0,13400379 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10231295 0,13393088 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10231295 0,13385805 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10231295 0,1337853 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10231295 0,13371263 ! memory GO:0007613 31 18 0,000 0,10231295 0,13364004 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10231295 0,13356753 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10231295 0,1334951 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10231295 0,13342274 GO:0042744|hydrogen peroxide catabolic process, ! glutamine metabolic process GO:0006541 29 18 0,000 0,10231295 0,13335046 ! response to retinoic acid GO:0032526 26 18 0,000 0,10231295 0,13327827 ! response to fungus GO:0009620 21 18 0,000 0,10231295 0,13320615 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10231295 0,1331341 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10231295 0,13306214 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10231295 0,13299025 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10231295 0,13291844 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10231295 0,13284671 ! vitamin transport GO:0051180 27 18 0,000 0,10231295 0,13277506 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10231295 0,13270348 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10231295 0,13263198 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10231295 0,13256056 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10231295 0,13248921 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,10231295 0,13241794 ! nerve development GO:0021675 28 18 0,000 0,10231295 0,13234675 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10231295 0,13227564 ! response to protein stimulus GO:0051789 149 91 1,000 0,10313519 0,13326707 ! regulation of defense response GO:0031347 149 92 1,000 0,10502972 0,13564225 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,10693371 0,1380271 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10693371 0,13795309 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,10693371 0,13787916 ! protein secretion GO:0009306 39 19 0,000 0,10768136 0,1387688 ! positive regulation of translation GO:0045727 30 19 0,000 0,10768136 0,13869451 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10768136 0,1386203 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10768136 0,13854617 ! skin development GO:0043588 36 19 0,000 0,10768136 0,13847212 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10768136 0,13839815 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10768136 0,13832426 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10768136 0,13825045 ! cerebral cortex development GO:0021987 36 19 0,000 0,10768136 0,13817672 ! pigmentation during development GO:0048066 41 19 0,000 0,10768136 0,13810306 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10768136 0,13802948 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10768136 0,13795599 ! heme metabolic process GO:0042168 36 19 0,000 0,10768136 0,13788257 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10768136 0,13780923 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10768136 0,13773596 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10768136 0,13766278 ! peptide cross-linking GO:0018149 37 19 0,000 0,10768136 0,13758967 ! heart process GO:0003015 30 19 0,000 0,10768136 0,13751664 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10768136 0,13744368 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10768136 0,13737081 ! visual learning GO:0008542 36 19 0,000 0,10768136 0,13729801 ! G1 phase GO:0051318 40 19 0,000 0,10768136 0,13722529 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10768136 0,13715264 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10768136 0,13708008 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10768136 0,13700758 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10768136 0,13693517 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10768136 0,13686283 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10768136 0,13679057 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10768136 0,13671839 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10768136 0,13664628 ! cilium assembly GO:0042384 37 19 0,000 0,10768136 0,13657425 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10768136 0,13650229 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11301784 0,14319163 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11301784 0,14311627 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11301784 0,14304098 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11301784 0,14296578 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11301784 0,14289065 ! response to vitamin GO:0033273 31 20 0,000 0,11301784 0,14281561 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11301784 0,14274064 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11301784 0,14266575 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11301784 0,14259093 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11301784 0,1425162 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11301784 0,14244155 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11301784 0,14236697 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11301784 0,14229247 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11301784 0,14221805 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,11301784 0,14214371 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11301784 0,14206944 ! body fluid secretion GO:0007589 31 20 0,000 0,11301784 0,14199525 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11301784 0,14192114 ! peptide secretion GO:0002790 35 20 0,000 0,11301784 0,14184711 ! stem cell differentiation GO:0048863 53 20 0,000 0,11301784 0,14177316 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11301784 0,14169928 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11301784 0,14162548 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11301784 0,14155175 ! sensory perception of pain GO:0019233 30 20 0,000 0,11301784 0,1414781 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11301784 0,14140453 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11301784 0,14133104 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11301784 0,14125762 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11301784 0,14118427 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11301784 0,14111101 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11301784 0,14103782 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11301784 0,1409647 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11301784 0,14089166 ! regulation of glucose import GO:0046324 29 20 0,000 0,11301784 0,1408187 GO:0010827|regulation of glucose transport, ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11301784 0,14074581 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11301784 0,140673 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11301784 0,14060026 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11301784 0,1405276 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,11658942 0,14489367 ! regulation of cell killing GO:0031341 42 21 0,000 0,11832258 0,14697167 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11832258 0,14689583 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11832258 0,14682007 ! hormone secretion GO:0046879 38 21 0,000 0,11832258 0,14674439 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11832258 0,14666879 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11832258 0,14659326 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11832258 0,14651782 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11832258 0,14644245 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11832258 0,14636716 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11832258 0,14629194 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11832258 0,1462168 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11832258 0,14614174 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11832258 0,14606676 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11832258 0,14599186 ! cytolysis GO:0019835 24 21 0,000 0,11832258 0,14591703 ! vasodilation GO:0042311 39 21 0,000 0,11832258 0,14584227 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11832258 0,1457676 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11832258 0,145693 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11832258 0,14561848 ! DNA modification GO:0006304 34 21 0,000 0,11832258 0,14554403 ! collagen fibril organization GO:0030199 59 21 0,000 0,11832258 0,14546966 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11832258 0,14539536 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11832258 0,14532114 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11832258 0,145247 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11832258 0,14517293 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11832258 0,14509894 ! collagen catabolic process GO:0030574 28 21 0,000 0,11832258 0,14502502 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11832258 0,14495118 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,11854649 0,14515158 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12359577 0,15125708 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12359577 0,15118018 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12359577 0,15110336 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12359577 0,15102662 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12359577 0,15094996 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12359577 0,15087337 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12359577 0,15079686 ! keratinization GO:0031424 28 22 0,000 0,12359577 0,15072043 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12359577 0,15064408 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12359577 0,15056781 ! sensory perception of taste GO:0050909 28 22 0,000 0,12359577 0,15049161 ! vacuolar transport GO:0007034 36 22 0,000 0,12359577 0,15041549 ! lysosome organization GO:0007040 41 22 0,000 0,12359577 0,15033944 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12359577 0,15026347 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12359577 0,15018758 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12359577 0,15011177 ! fucose metabolic process GO:0006004 39 22 0,000 0,12359577 0,15003603 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12359577 0,14996037 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12359577 0,14988479 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12359577 0,14980928 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12359577 0,14973384 ! sarcomere organization GO:0045214 30 22 0,000 0,12359577 0,14965849 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12359577 0,14958321 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12359577 0,149508 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,12359577 0,14943287 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12883759 0,15569224 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12883759 0,15561408 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12883759 0,155536 ! gluconeogenesis GO:0006094 33 23 0,000 0,12883759 0,155458 ! viral genome replication GO:0019079 41 23 0,000 0,12883759 0,15538007 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12883759 0,15530223 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12883759 0,15522446 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12883759 0,15514677 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12883759 0,15506916 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12883759 0,15499162 ! visual behavior GO:0007632 42 23 0,000 0,12883759 0,15491417 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12883759 0,15483679 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12883759 0,15475949 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12883759 0,15468226 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12883759 0,15460511 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12883759 0,15452804 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12883759 0,15445105 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12883759 0,15437413 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12883759 0,15429729 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12883759 0,15422052 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12883759 0,15414383 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12883759 0,15406722 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12883759 0,15399069 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12883759 0,15391423 ! fatty acid transport GO:0015908 44 23 0,000 0,12883759 0,15383784 ! platelet activation GO:0030168 37 23 0,000 0,12883759 0,15376153 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12883759 0,1536853 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12883759 0,15360914 ! hormone transport GO:0009914 40 23 0,000 0,12883759 0,15353306 ! cell-cell recognition GO:0009988 25 23 0,000 0,12883759 0,15345705 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12883759 0,15338112 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12883759 0,15330527 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12883759 0,15322949 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13404824 0,15934786 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13404824 0,15926917 ! vesicle docking GO:0048278 47 24 0,000 0,13404824 0,15919056 ! spinal cord development GO:0021510 47 24 0,000 0,13404824 0,15911202 ! vacuole organization GO:0007033 43 24 0,000 0,13404824 0,15903356 ! digestive system process GO:0022600 39 24 0,000 0,13404824 0,15895518 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13404824 0,15887688 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13404824 0,15879865 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13404824 0,15872051 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13404824 0,15864243 ! membrane depolarization GO:0051899 39 24 0,000 0,13404824 0,15856444 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13404824 0,15848652 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13404824 0,15840868 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13404824 0,15833091 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13404824 0,15825322 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13404824 0,15817561 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13404824 0,15809807 ! regulation of amine transport GO:0051952 40 24 0,000 0,13404824 0,15802061 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13922789 0,16404619 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13922789 0,16396589 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13922789 0,16388567 ! phototransduction GO:0007602 33 25 0,000 0,13922789 0,16380553 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13922789 0,16372547 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,13922789 0,16364549 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13922789 0,16356558 ! chromosome condensation GO:0030261 45 25 0,000 0,13922789 0,16348576 ! response to starvation GO:0042594 42 25 0,000 0,13922789 0,16340601 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13922789 0,16332634 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,13922789 0,16324674 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13922789 0,16316723 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13922789 0,16308779 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13922789 0,16300843 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13922789 0,16292914 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13922789 0,16284993 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13922789 0,1627708 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13922789 0,16269175 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13922789 0,16261277 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13922789 0,16253387 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13922789 0,16245505 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13922789 0,1623763 ! telomere organization GO:0032200 43 25 0,000 0,13922789 0,16229763 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,13922789 0,16221904 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14437674 0,1681367 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14437674 0,16805536 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14437674 0,1679741 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14437674 0,16789291 ! initiation of viral infection GO:0019059 57 26 0,000 0,14437674 0,1678118 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14437674 0,16773077 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14437674 0,16764982 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14437674 0,16756895 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14437674 0,16748815 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14437674 0,16740744 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14437674 0,1673268 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14437674 0,16724624 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14437674 0,16716575 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14437674 0,16708534 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,14437674 0,16700501 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14437674 0,16692476 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14437674 0,16684459 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14437674 0,16676449 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14437674 0,16668447 ! neuron fate commitment GO:0048663 48 27 0,000 0,14949495 0,17251072 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14949495 0,17242802 ! iron ion transport GO:0006826 59 27 0,000 0,14949495 0,1723454 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14949495 0,17226286 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14949495 0,1721804 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14949495 0,17209802 ! fat cell differentiation GO:0045444 50 27 0,000 0,14949495 0,17201571 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14949495 0,17193349 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14949495 0,17185134 ! autophagy GO:0006914 41 27 0,000 0,14949495 0,17176927 ! base-excision repair GO:0006284 41 27 0,000 0,14949495 0,17168728 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14949495 0,17160537 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14949495 0,17152354 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,14949495 0,17144178 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14949495 0,1713601 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14949495 0,1712785 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14949495 0,17119698 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15458272 0,17693912 ! circadian rhythm GO:0007623 50 28 0,000 0,15458272 0,17685498 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15458272 0,17677092 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15458272 0,17668695 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,15458272 0,17660305 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15458272 0,17651923 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,15458272 0,17643549 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15458272 0,17635184 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15458272 0,17626826 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15458272 0,17618476 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15458272 0,17610134 ! synaptogenesis GO:0007416 42 28 0,000 0,15458272 0,17601799 ! lipid oxidation GO:0034440 43 28 0,000 0,15458272 0,17593473 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15458272 0,17585155 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15964022 0,18151908 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15964022 0,18143333 ! regulation of pH GO:0006885 43 29 0,000 0,15964022 0,18134767 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15964022 0,18126209 ! catechol metabolic process GO:0009712 54 29 0,000 0,15964022 0,18117659 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15964022 0,18109117 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15964022 0,18100583 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15964022 0,18092057 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15964022 0,18083539 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15964022 0,18075029 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15964022 0,18066527 ! detection of light stimulus GO:0009583 38 29 0,000 0,15964022 0,18058033 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15964022 0,18049547 ! regulation of coagulation GO:0050818 46 29 0,000 0,15964022 0,18041069 ! phenol metabolic process GO:0018958 55 30 0,000 0,16466763 0,18600484 ! zinc ion transport GO:0006829 45 30 0,000 0,16466763 0,18591756 ! membrane docking GO:0022406 61 30 0,000 0,16466763 0,18583036 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16466763 0,18574323 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16466763 0,18565619 ! acute-phase response GO:0006953 49 30 0,000 0,16466763 0,18556924 ! myofibril assembly GO:0030239 47 30 0,000 0,16466763 0,18548236 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16466763 0,18539556 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16466763 0,18530885 ! phospholipid transport GO:0015914 51 30 0,000 0,16466763 0,18522222 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16466763 0,18513566 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16466763 0,18504919 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16466763 0,1849628 ! eye morphogenesis GO:0048592 60 30 0,000 0,16466763 0,18487649 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16966513 0,19039846 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16966513 0,1903097 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16966513 0,19022102 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16966513 0,19013242 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16966513 0,1900439 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16966513 0,18995547 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16966513 0,18986712 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16966513 0,18977885 ! peptide transport GO:0015833 55 31 0,000 0,16966513 0,18969066 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16966513 0,18960256 ! mesoderm formation GO:0001707 69 31 0,000 0,16966513 0,18951453 ! natural killer cell activation GO:0030101 45 31 0,000 0,16966513 0,18942659 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16966513 0,18933873 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16966513 0,18925095 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16966513 0,18916326 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16966513 0,18907564 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1746329 0,19452165 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1746329 0,19443163 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1746329 0,1943417 ! cholesterol transport GO:0030301 56 32 0,000 0,1746329 0,19425185 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1746329 0,19416209 ! spliceosome assembly GO:0000245 67 32 0,000 0,1746329 0,19407241 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1746329 0,19398281 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,1746329 0,19389329 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,1746329 0,19380385 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1746329 0,1937145 ! muscle cell development GO:0055001 49 32 0,000 0,1746329 0,19362523 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1746329 0,19353605 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1746329 0,19344694 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,1746329 0,19335792 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,1746329 0,19326898 ! BMP signaling pathway GO:0030509 64 32 0,000 0,1746329 0,19318012 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,1746329 0,19309134 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1746329 0,19300264 ! gene silencing GO:0016458 65 32 0,000 0,1746329 0,19291403 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17957111 0,19827815 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17957111 0,1981872 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17957111 0,19809633 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17957111 0,19800554 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17957111 0,19791484 ! cell fate specification GO:0001708 52 33 0,000 0,17957111 0,19782422 ! sterol transport GO:0015918 57 33 0,000 0,17957111 0,19773368 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,17957111 0,19764323 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17957111 0,19755285 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17957111 0,19746257 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17957111 0,19737236 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18447994 0,20267522 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18447994 0,20258272 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,18447994 0,2024903 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18447994 0,20239796 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18447994 0,20230571 ! mismatch repair GO:0006298 46 34 0,000 0,18447994 0,20221355 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18447994 0,20212146 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18935956 0,20737328 ! odontogenesis GO:0042476 66 35 0,000 0,18935956 0,20727894 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18935956 0,20718467 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18935956 0,2070905 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,18935956 0,20699641 ! vesicle localization GO:0051648 64 35 0,000 0,18935956 0,20690241 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19421014 0,21210604 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19421014 0,2120098 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,19421014 0,21191365 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19421014 0,21181759 ! aerobic respiration GO:0009060 55 36 0,000 0,19421014 0,21172162 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19421014 0,21162573 ! meiosis I GO:0007127 65 37 0,000 0,19903186 0,21678165 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19903186 0,21668356 ! organic anion transport GO:0015711 68 37 0,000 0,19903186 0,21658556 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19903186 0,21648764 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19903186 0,21638982 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19903186 0,21629208 GO:0015986|ATP synthesis coupled proton transport, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20382489 0,22140076 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20382489 0,22130085 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20382489 0,22120103 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20382489 0,2211013 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20382489 0,22100166 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20382489 0,22090211 ! mRNA catabolic process GO:0006402 71 39 0,000 0,2085894 0,22596402 ! ear morphogenesis GO:0042471 60 39 0,000 0,2085894 0,22586233 ! ion transmembrane transport GO:0034220 66 39 0,000 0,2085894 0,22576072 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,2085894 0,22565921 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,2085894 0,22555779 ! RNA modification GO:0009451 57 39 0,000 0,2085894 0,22545646 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,2085894 0,22535523 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21332555 0,23036861 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21332555 0,23026526 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21332555 0,230162 ! feeding behavior GO:0007631 59 40 0,000 0,21332555 0,23005884 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21332555 0,22995576 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21803351 0,23492549 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,21803351 0,23482033 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,21803351 0,23471527 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21803351 0,2346103 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21803351 0,23450542 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,21803351 0,23440064 ! polyol metabolic process GO:0019751 66 41 0,000 0,21803351 0,23429595 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,22271345 0,23921811 ! regulation of tube size GO:0035150 71 42 0,000 0,22271345 0,23911136 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22271345 0,23900471 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,22271345 0,23889816 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22271345 0,2387917 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22271345 0,23868533 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22736554 0,24356255 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22736554 0,24345416 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22736554 0,24334586 ! striated muscle contraction GO:0006941 77 43 0,000 0,22736554 0,24323766 ! phagocytosis GO:0006909 90 43 0,000 0,22736554 0,24312955 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22736554 0,24302154 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23198994 0,24785426 ! biopolymer methylation GO:0043414 84 44 0,000 0,23198994 0,24774425 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23198994 0,24763434 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,23198994 0,24752452 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,23658682 0,25231732 ! glycolysis GO:0006096 65 45 0,000 0,23658682 0,25220553 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,23658682 0,25209383 ! leukocyte migration GO:0050900 68 45 0,000 0,23658682 0,25198224 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,23658682 0,25187074 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,23658682 0,25175934 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,23658682 0,25164804 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,23658682 0,25153684 ! cell growth GO:0016049 84 45 0,000 0,23658682 0,25142574 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,24115633 0,25616871 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,24115633 0,25605566 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24569864 0,26076353 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24569864 0,26064856 ! methylation GO:0032259 90 47 0,000 0,24569864 0,26053368 ! protein homooligomerization GO:0051260 76 47 0,000 0,24569864 0,26041891 ! Notch signaling pathway GO:0007219 96 48 0,000 0,25021391 0,26508792 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25021391 0,26497125 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,25021391 0,26485467 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25470231 0,26948714 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,25470231 0,26936868 ! regulation of ion transport GO:0043269 77 49 0,000 0,25470231 0,26925033 ! peptide metabolic process GO:0006518 76 49 0,000 0,25470231 0,26913208 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,25470231 0,26901394 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25470231 0,2688959 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25470231 0,26877796 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,25470231 0,26866013 ! neuromuscular process GO:0050905 99 50 0,000 0,25916398 0,27324651 ! inner ear development GO:0048839 79 50 0,000 0,25916398 0,27312682 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,25916398 0,27300724 ! viral infectious cycle GO:0019058 99 51 0,000 0,26359909 0,27755773 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,26359909 0,27743631 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,26359909 0,277315 ! excretion GO:0007588 83 51 0,000 0,26359909 0,2771938 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,26359909 0,2770727 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,26359909 0,27695171 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,2680078 0,28146083 ! amino acid activation GO:0043038 92 52 0,000 0,2680078 0,28133803 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 0,000 0,27239025 0,28581376 ! regulation of translational initiation GO:0006446 82 53 0,000 0,27239025 0,28568917 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,27239025 0,28556468 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27239025 0,28544031 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,27239025 0,28531604 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,27239025 0,28519188 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,27674662 0,28962695 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,27674662 0,28950103 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27674662 0,28937521 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27674662 0,28924951 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27674662 0,28912391 ! chloride transport GO:0006821 90 55 0,000 0,28107704 0,29352056 ! glucose catabolic process GO:0006007 82 55 0,000 0,28107704 0,29339322 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,28107704 0,29326599 ! gastrulation GO:0007369 112 55 0,000 0,28107704 0,29313887 ! regulation of actin filament length GO:0030832 105 56 0,000 0,28538169 0,29749928 ! sensory perception of smell GO:0007608 80 56 0,000 0,28538169 0,29737044 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28538169 0,2972417 ! proton transport GO:0015992 94 56 0,000 0,28538169 0,29711308 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,28538169 0,29698457 ! hydrogen transport GO:0006818 97 58 0,000 0,29391422 0,30573179 ! regulation of endocytosis GO:0030100 91 58 0,000 0,29391422 0,30559966 ! adult behavior GO:0030534 99 58 0,000 0,29391422 0,30546766 ! positive regulation of secretion GO:0051047 95 59 0,000 0,29814242 0,30972827 ! regulation of cellular component size GO:0032535 109 59 0,000 0,29814242 0,30959459 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,29814242 0,30946103 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29814242 0,30932759 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,29814242 0,30919425 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,29814242 0,30906104 ! establishment of organelle localization GO:0051656 109 59 0,000 0,29814242 0,30892794 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,30234544 0,31314814 ! regulation of heart contraction GO:0008016 110 60 0,000 0,30234544 0,3130134 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,30234544 0,31287877 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30652343 0,31706594 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,30652343 0,31692969 ! mesoderm development GO:0007498 119 61 0,000 0,30652343 0,31679355 ! tRNA processing GO:0008033 89 61 0,000 0,30652343 0,31665753 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30652343 0,31652162 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,31067654 0,32067257 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,31480491 0,32479443 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,31480491 0,32465521 ! detection of external stimulus GO:0009581 91 63 0,000 0,31480491 0,32451612 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,31480491 0,32437714 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31890869 0,32846503 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31890869 0,32832448 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32298804 0,33238204 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,32298804 0,33223994 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,32298804 0,33209795 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32704308 0,33612373 ! extracellular matrix organization GO:0030198 133 66 0,000 0,32704308 0,33598021 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,33107397 0,33997608 ! hexose catabolic process GO:0019320 104 67 0,000 0,33107397 0,33983104 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,33107397 0,33968613 ! activation of immune response GO:0002253 105 67 0,000 0,33107397 0,33954133 ! amino acid transport GO:0006865 125 68 0,000 0,33508085 0,34350427 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33508085 0,34335797 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,33508085 0,3432118 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33906386 0,34714367 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33906386 0,34699602 ! antigen processing and presentation GO:0019882 104 69 0,000 0,33906386 0,34684848 ! amine catabolic process GO:0009310 117 71 0,000 0,34695883 0,35477388 ! regulation of immune effector process GO:0002697 137 71 0,000 0,34695883 0,35462317 ! acute inflammatory response GO:0002526 113 72 0,000 0,35087108 0,35846956 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,35087108 0,35831741 ! regulation of blood pressure GO:0008217 125 73 0,000 0,35476002 0,36213518 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,35476002 0,3619816 ! transition metal ion transport GO:0000041 126 74 0,000 0,35862579 0,36577094 ! neurotransmitter transport GO:0006836 123 74 0,000 0,35862579 0,36561595 ! exocytosis GO:0006887 133 74 0,000 0,35862579 0,3654611 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,35862579 0,36530637 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,35862579 0,36515178 ! organelle localization GO:0051640 136 74 0,000 0,35862579 0,36499732 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36246853 0,36875234 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,36246853 0,36859648 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,36628837 0,37232354 ! defense response to bacterium GO:0042742 89 76 0,000 0,36628837 0,37216631 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,36628837 0,37200921 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,36628837 0,37185224 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,37008545 0,37554854 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,37008545 0,37539022 ! blood coagulation GO:0007596 146 78 0,000 0,3738599 0,37905897 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,37761187 0,38270183 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37761187 0,3825407 ! inorganic anion transport GO:0015698 138 80 0,000 0,38134147 0,38615639 ! digestion GO:0007586 112 81 0,000 0,38504885 0,38974654 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,38504885 0,38958265 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,38873414 0,393146 ! hemostasis GO:0007599 158 84 0,000 0,39603895 0,40036542 ! response to unfolded protein GO:0006986 131 85 0,000 0,39965873 0,40385506 ! nucleosome assembly GO:0006334 122 85 0,000 0,39965873 0,40368552 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,39965873 0,40351612 ! amine biosynthetic process GO:0009309 138 86 0,000 0,40325694 0,40697827 ! chromatin assembly GO:0031497 124 86 0,000 0,40325694 0,40680763 ! alcohol catabolic process GO:0046164 130 86 0,000 0,40325694 0,40663713 ! amine transport GO:0015837 155 86 0,000 0,40325694 0,40646678 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,4068337 0,40990029 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,41038914 0,41330945 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,41038914 0,41313652 ! cellular defense response GO:0006968 114 89 0,000 0,41392339 0,41652015 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41743657 0,41987976 ! sterol metabolic process GO:0016125 152 91 0,000 0,42092881 0,42321551 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,42092881 0,42303873 ! nucleosome organization GO:0034728 138 92 0,000 0,42440023 0,42634946 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,42440023 0,42617152 ! vitamin metabolic process GO:0006766 139 92 0,000 0,42440023 0,42599372 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,4312811 0,43271991 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,4346908 0,43595918 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,43808017 0,43917537 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,43808017 0,43899246 ! positive regulation of immune response GO:0050778 156 96 0,000 0,43808017 0,4388097 ! detection of stimulus GO:0051606 151 96 0,000 0,43808017 0,43862709 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,44144933 0,44181659 ! hormone metabolic process GO:0042445 157 97 0,000 0,44144933 0,44163289 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,4447984 0,4447984 GO:0016054|organic acid catabolic process,