pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6935-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 1,954E-11 4,702E-08 ! negative regulation of phosphorylation GO:0042326 47 24 5,000 1,156E-08 1,391E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 5,000 1,955E-08 1,568E-05 GO:0045936|negative regulation of phosphate metabolic process, ! induction of apoptosis by intracellular signals GO:0008629 93 45 6,000 2,303E-08 1,385E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 2,608E-07 1,255E-04 ! positive regulation of locomotion GO:0040017 39 21 4,000 2,655E-07 1,065E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 4,000 3,416E-07 1,174E-04 ! cell cycle arrest GO:0007050 213 100 7,000 4,54E-07 1,365E-04 ! regulation of behavior GO:0050795 43 24 4,000 5,453E-07 1,458E-04 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 1,008E-06 2,426E-04 GO:0050927|positive regulation of positive chemotaxis, ! response to UV GO:0009411 104 53 5,000 1,672E-06 3,657E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 2,017E-06 4,044E-04 ! L-serine biosynthetic process GO:0006564 6 5 2,000 3,122E-06 5,778E-04 ! filopodium assembly GO:0046847 32 16 3,000 3,628E-06 6,235E-04 ! microspike assembly GO:0030035 36 17 3,000 4,719E-06 7,569E-04 ! establishment or maintenance of cell polarity GO:0007163 83 37 4,000 5,202E-06 7,823E-04 ! developmental maturation GO:0021700 116 66 5,000 6,147E-06 8,699E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 6,213E-06 8,304E-04 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 2,000 6,213E-06 7,867E-04 ! nuclear migration GO:0007097 12 6 2,000 6,213E-06 7,474E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 6,213E-06 7,118E-04 GO:0031272|regulation of pseudopodium assembly, ! negative regulation of protein kinase activity GO:0006469 130 67 5,000 6,713E-06 7,342E-04 ! negative regulation of kinase activity GO:0033673 131 68 5,000 7,321E-06 7,658E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 9,452E-06 9,476E-04 ! pancreas development GO:0031016 35 20 3,000 9,452E-06 9,097E-04 ! regulation of intracellular protein transport GO:0033157 80 42 4,000 9,875E-06 9,138E-04 ! negative regulation of transferase activity GO:0051348 140 72 5,000 1,022E-05 9,103E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,082E-05 9,295E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,082E-05 8,975E-04 ! macrophage differentiation GO:0030225 11 7 2,000 1,082E-05 8,676E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 1,082E-05 8,396E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 1,111E-05 8,355E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 1,111E-05 8,102E-04 ! positive regulation of inflammatory response GO:0050729 35 21 3,000 1,161E-05 8,219E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 1,412E-05 9,706E-04 ! positive regulation of intracellular transport GO:0032388 37 22 3,000 1,412E-05 9,436E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 1,556E-05 1,012E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 4,000 1,556E-05 9,854E-04 ! positive regulation of protein transport GO:0051222 72 46 4,000 1,556E-05 9,601E-04 ! response to molecule of bacterial origin GO:0002237 34 23 3,000 1,7E-05 1,023E-03 ! ER overload response GO:0006983 12 8 2,000 1,722E-05 1,011E-03 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 1,722E-05 9,865E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,722E-05 9,636E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,722E-05 9,417E-04 ! regulation of inflammatory response GO:0050727 75 48 4,000 1,923E-05 1,028E-03 ! vasculogenesis GO:0001570 46 25 3,000 2,403E-05 1,257E-03 ! negative regulation of transport GO:0051051 153 84 5,000 2,483E-05 1,271E-03 ! regulation of angiogenesis GO:0045765 114 52 4,000 2,854E-05 1,431E-03 ! regulation of protein transport GO:0051223 154 87 5,000 3,033E-05 1,489E-03 GO:0070201|regulation of establishment of protein localization, ! cell maturation GO:0048469 100 53 4,000 3,134E-05 1,508E-03 ! L-serine metabolic process GO:0006563 18 10 2,000 3,653E-05 1,723E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 3,653E-05 1,69E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 3,653E-05 1,658E-03 ! DNA ligation GO:0006266 19 10 2,000 3,653E-05 1,628E-03 ! protein sumoylation GO:0016925 15 10 2,000 3,653E-05 1,598E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 3,653E-05 1,569E-03 ! negative regulation of protein modification process GO:0031400 60 28 3,000 3,827E-05 1,615E-03 ! regulation of intracellular transport GO:0032386 101 57 4,000 4,473E-05 1,855E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 4,997E-05 2,038E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 4,997E-05 2,004E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 4,997E-05 1,971E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 4,997E-05 1,939E-03 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 19 11 2,000 4,997E-05 1,909E-03 ! regulation of protein localization GO:0032880 176 97 5,000 5,608E-05 2,108E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 6,63E-05 2,454E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 6,63E-05 2,417E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 6,63E-05 2,381E-03 ! leukocyte chemotaxis GO:0030595 50 33 3,000 7,446E-05 2,635E-03 GO:0060326|cell chemotaxis, ! response to X-ray GO:0010165 25 13 2,000 8,575E-05 2,99E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 8,575E-05 2,947E-03 ! cell projection assembly GO:0030031 120 66 4,000 9,082E-05 3,078E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 9,761E-05 3,262E-03 ! response to gamma radiation GO:0010332 28 14 2,000 1,086E-04 3,579E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,086E-04 3,531E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,351E-04 4,332E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,351E-04 4,275E-03 ! regulation of caspase activity GO:0043281 122 72 4,000 1,376E-04 4,298E-03 ! regulation of endopeptidase activity GO:0052548 125 74 4,000 1,566E-04 4,831E-03 ! regulation of hormone secretion GO:0046883 62 40 3,000 1,602E-04 4,879E-03 ! mesenchymal cell development GO:0014031 87 40 3,000 1,602E-04 4,818E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 1,654E-04 4,912E-03 ! myoblast differentiation GO:0045445 45 17 2,000 1,998E-04 5,863E-03 ! negative regulation of protein catabolic process GO:0042177 40 17 2,000 1,998E-04 5,792E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,998E-04 5,723E-03 ! activation of protein kinase activity GO:0032147 147 79 4,000 2,132E-04 6,034E-03 ! regulation of peptidase activity GO:0052547 134 79 4,000 2,132E-04 5,964E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 2,132E-04 5,895E-03 ! neuron maturation GO:0042551 42 18 2,000 2,386E-04 6,523E-03 ! response to retinoic acid GO:0032526 26 18 2,000 2,386E-04 6,449E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 2,397E-04 6,407E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to nutrient GO:0007584 125 82 4,000 2,538E-04 6,711E-03 ! leukocyte migration GO:0050900 68 45 3,000 2,543E-04 6,65E-03 ! pigmentation GO:0043473 100 46 3,000 2,77E-04 7,167E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 2,819E-04 7,215E-03 ! response to vitamin A GO:0033189 27 19 2,000 2,819E-04 7,139E-03 ! positive regulation of defense response GO:0031349 76 47 3,000 3,012E-04 7,548E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 3,268E-04 8,106E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 3,268E-04 8,024E-03 ! response to vitamin GO:0033273 31 20 2,000 3,299E-04 8,019E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 3,299E-04 7,938E-03 ! regulation of glucose import GO:0046324 29 20 2,000 3,299E-04 7,86E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 3,83E-04 9,034E-03 ! cell aging GO:0007569 44 21 2,000 3,83E-04 8,946E-03 ! DNA modification GO:0006304 34 21 2,000 3,83E-04 8,86E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 4,131E-04 9,465E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 3,000 4,131E-04 9,376E-03 ! regulation of defense response GO:0031347 149 92 4,000 4,329E-04 9,735E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 4,412E-04 9,83E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 4,412E-04 9,74E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 4,412E-04 9,651E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,593E-04 9,956E-03 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 4,593E-04 9,867E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 4,593E-04 9,78E-03 ! Notch receptor processing GO:0007220 8 5 1,000 4,593E-04 9,694E-03 ! response to protozoan GO:0001562 10 5 1,000 4,593E-04 9,61E-03 ! anagen GO:0042640 6 5 1,000 4,593E-04 9,527E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 4,593E-04 9,446E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 4,593E-04 9,366E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 4,593E-04 9,287E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 4,593E-04 9,209E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 4,593E-04 9,133E-03 ! microvillus organization GO:0032528 7 5 1,000 4,593E-04 9,058E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,593E-04 8,985E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 4,593E-04 8,912E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 4,593E-04 8,841E-03 ! depyrimidination GO:0045008 10 5 1,000 4,593E-04 8,771E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 4,593E-04 8,702E-03 ! decidualization GO:0046697 11 5 1,000 4,593E-04 8,634E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 4,593E-04 8,567E-03 ! enteric nervous system development GO:0048484 8 5 1,000 4,593E-04 8,501E-03 ! circadian behavior GO:0048512 13 5 1,000 4,593E-04 8,436E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 4,593E-04 8,372E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,593E-04 8,309E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 5,017E-04 9,009E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 5,049E-04 8,998E-03 ! sex determination GO:0007530 47 23 2,000 5,049E-04 8,932E-03 ! negative regulation of catabolic process GO:0009895 50 23 2,000 5,049E-04 8,867E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 5,519E-04 9,622E-03 ! interphase GO:0051325 213 98 4,000 5,784E-04 0,01001241 ! skeletal muscle fiber development GO:0048741 111 56 3,000 5,912E-04 0,01015951 ! skeletal muscle tissue development GO:0007519 186 99 4,000 6,059E-04 0,01033835 GO:0060538|skeletal muscle organ development, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 6,324E-04 0,01071518 ! muscle fiber development GO:0048747 112 57 3,000 6,324E-04 0,01064025 ! positive regulation of cell migration GO:0030335 126 57 3,000 6,324E-04 0,01056636 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 6,491E-04 0,01077079 ! negative regulation of DNA replication GO:0008156 42 25 2,000 6,491E-04 0,01069702 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 6,491E-04 0,01062425 ! negative regulation of cell development GO:0010721 73 25 2,000 6,491E-04 0,01055246 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 2,000 6,491E-04 0,01048164 ! sleep GO:0030431 13 6 1,000 6,859E-04 0,01100148 ! male meiosis GO:0007140 7 6 1,000 6,859E-04 0,01092863 ! neuron remodeling GO:0016322 15 6 1,000 6,859E-04 0,01085673 ! erythrocyte maturation GO:0043249 7 6 1,000 6,859E-04 0,01078577 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 6,859E-04 0,01071573 ! activation of MAPKKK activity GO:0000185 12 6 1,000 6,859E-04 0,0106466 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 6,859E-04 0,01057835 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 6,859E-04 0,01051097 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 6,859E-04 0,01044445 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 9 6 1,000 6,859E-04 0,01037876 ! establishment of spindle localization GO:0051293 12 6 1,000 6,859E-04 0,01031389 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,859E-04 0,01024983 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 11 6 1,000 6,859E-04 0,01018656 ! hair follicle maturation GO:0048820 7 6 1,000 6,859E-04 0,01012406 ! neutrophil homeostasis GO:0001780 10 6 1,000 6,859E-04 0,01006233 ! salivary gland morphogenesis GO:0007435 13 6 1,000 6,859E-04 0,01000135 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 6,859E-04 9,941E-03 ! organ or tissue specific immune response GO:0002251 7 6 1,000 6,859E-04 9,882E-03 ! maternal placenta development GO:0001893 12 6 1,000 6,859E-04 9,823E-03 ! positive regulation of secretion GO:0051047 95 59 3,000 7,209E-04 0,01026366 ! cytokine-mediated signaling pathway GO:0019221 97 59 3,000 7,209E-04 0,01020329 ! establishment of organelle localization GO:0051656 109 59 3,000 7,209E-04 0,01014362 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 7,301E-04 0,01021284 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 7,301E-04 0,01015381 ! blastocyst development GO:0001824 49 26 2,000 7,301E-04 0,01009545 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 7,683E-04 0,0105634 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 8,172E-04 0,01117197 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 2,000 8,172E-04 0,01110885 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 8,172E-04 0,01104644 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 8,172E-04 0,01098473 ! fat cell differentiation GO:0045444 50 27 2,000 8,172E-04 0,01092371 ! base-excision repair GO:0006284 41 27 2,000 8,172E-04 0,01086335 ! regulation of chromosome organization GO:0033044 42 27 2,000 8,172E-04 0,01080366 ! gonad development GO:0008406 98 62 3,000 8,697E-04 0,01143378 ! regulation of homeostatic process GO:0032844 134 62 3,000 8,697E-04 0,01137164 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 9,107E-04 0,01184416 ! regulation of helicase activity GO:0051095 15 7 1,000 9,559E-04 0,01236506 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 9,559E-04 0,01229893 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 9,559E-04 0,01223351 ! mRNA stabilization GO:0048255 18 7 1,000 9,559E-04 0,01216879 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 9,559E-04 0,01210474 ! rhythmic behavior GO:0007622 15 7 1,000 9,559E-04 0,01204136 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 9,559E-04 0,01197865 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 1,000 9,559E-04 0,01191658 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 9,559E-04 0,01185516 ! centrosome duplication GO:0051298 13 7 1,000 9,559E-04 0,01179436 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 9,559E-04 0,01173419 ! B cell lineage commitment GO:0002326 21 7 1,000 9,559E-04 0,01167462 ! T cell lineage commitment GO:0002360 16 7 1,000 9,559E-04 0,01161566 ! response to tumor cell GO:0002347 13 7 1,000 9,559E-04 0,01155729 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 9,559E-04 0,0114995 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 9,559E-04 0,01144229 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 9,559E-04 0,01138565 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 9,559E-04 0,01132956 ! positive regulation of cell motion GO:0051272 146 64 3,000 9,8E-04 0,01155875 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,011E-03 0,01186214 ! regulation of pH GO:0006885 43 29 2,000 1,011E-03 0,01180456 ! regulation of peptide secretion GO:0002791 47 29 2,000 1,011E-03 0,01174753 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,011E-03 0,01169105 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,039E-03 0,01195832 ! actin filament organization GO:0007015 148 66 3,000 1,1E-03 0,01260207 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 2,000 1,117E-03 0,01274116 ! regulation of B cell activation GO:0050864 50 30 2,000 1,117E-03 0,01268106 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,164E-03 0,01314344 ! chromosome segregation GO:0007059 113 67 3,000 1,164E-03 0,01308202 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 1,231E-03 0,01377445 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,269E-03 0,01413298 ! prostaglandin biosynthetic process GO:0001516 14 8 1,000 1,269E-03 0,01406785 GO:0046457|prostanoid biosynthetic process, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,269E-03 0,01400332 ! negative regulation of muscle cell differentiation GO:0051148 15 8 1,000 1,269E-03 0,01393938 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,269E-03 0,01387601 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,269E-03 0,01381323 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,269E-03 0,01375101 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,269E-03 0,01368934 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,269E-03 0,01362823 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 1,269E-03 0,01356766 ! DNA topological change GO:0006265 12 8 1,000 1,269E-03 0,01350762 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,269E-03 0,01344812 ! myeloid cell homeostasis GO:0002262 13 8 1,000 1,269E-03 0,01338914 ! blastocyst growth GO:0001832 19 8 1,000 1,269E-03 0,01333067 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,269E-03 0,01327271 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 1,000 1,269E-03 0,01321525 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,269E-03 0,01315829 ! negative regulation of cell size GO:0045792 134 69 3,000 1,299E-03 0,01340865 ! urogenital system development GO:0001655 137 69 3,000 1,299E-03 0,01335134 ! metanephros development GO:0001656 74 32 2,000 1,351E-03 0,01383615 ! response to ionizing radiation GO:0010212 65 32 2,000 1,351E-03 0,01377752 ! response to mechanical stimulus GO:0009612 57 32 2,000 1,351E-03 0,01371939 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,351E-03 0,01366174 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 1,351E-03 0,01360458 ! reproductive structure development GO:0048608 113 71 3,000 1,444E-03 0,01447628 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,479E-03 0,01476651 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 1,521E-03 0,0151207 ! microtubule bundle formation GO:0001578 21 9 1,000 1,624E-03 0,01607927 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,624E-03 0,01601337 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 1,624E-03 0,01594801 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,624E-03 0,01588318 ! receptor clustering GO:0043113 18 9 1,000 1,624E-03 0,01581888 ! motor axon guidance GO:0008045 16 9 1,000 1,624E-03 0,01575509 ! base-excision repair, AP site formation GO:0006285 14 9 1,000 1,624E-03 0,01569182 ! erythrocyte development GO:0048821 15 9 1,000 1,624E-03 0,01562905 ! postreplication repair GO:0006301 22 9 1,000 1,624E-03 0,01556678 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,624E-03 0,01550501 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,624E-03 0,01544373 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,624E-03 0,01538292 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,683E-03 0,01587988 GO:0090046|regulation of transcription regulator activity, ! organelle localization GO:0051640 136 74 3,000 1,683E-03 0,01581785 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,757E-03 0,01644513 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,757E-03 0,01638139 ! calcium-mediated signaling GO:0019722 62 35 2,000 1,757E-03 0,01631814 ! development of primary sexual characteristics GO:0045137 124 76 3,000 1,857E-03 0,01718276 ! regulation of catabolic process GO:0009894 161 76 3,000 1,857E-03 0,01711692 ! cell junction organization GO:0034330 86 36 2,000 1,907E-03 0,01750971 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,907E-03 0,01744313 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,021E-03 0,01841707 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,021E-03 0,01834757 ! lung alveolus development GO:0048286 26 10 1,000 2,021E-03 0,01827859 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 2,021E-03 0,01821013 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 2,021E-03 0,01814219 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 2,021E-03 0,01807474 ! multicellular organism growth GO:0035264 18 10 1,000 2,021E-03 0,0180078 ! regulation of bone resorption GO:0045124 25 10 1,000 2,021E-03 0,01794135 ! regulation of gliogenesis GO:0014013 23 10 1,000 2,021E-03 0,01787539 GO:0045685|regulation of glial cell differentiation, ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 2,021E-03 0,01780991 ! salivary gland development GO:0007431 27 10 1,000 2,021E-03 0,01774491 ! apical protein localization GO:0045176 15 10 1,000 2,021E-03 0,01768038 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 2,021E-03 0,01761632 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 2,021E-03 0,01755273 ! oocyte development GO:0048599 17 10 1,000 2,021E-03 0,01748959 ! blastocyst formation GO:0001825 17 10 1,000 2,021E-03 0,0174269 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,021E-03 0,01736466 ! localization within membrane GO:0051668 20 10 1,000 2,021E-03 0,01730287 ! response to steroid hormone stimulus GO:0048545 137 78 3,000 2,043E-03 0,01742788 ! protein oligomerization GO:0051259 139 78 3,000 2,043E-03 0,0173663 ! monovalent inorganic cation homeostasis GO:0055067 58 37 2,000 2,065E-03 0,01749068 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,065E-03 0,01742931 ! carbohydrate homeostasis GO:0033500 53 38 2,000 2,23E-03 0,01876278 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 2,000 2,23E-03 0,01869741 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 2,23E-03 0,01863249 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 2,000 2,404E-03 0,02001479 ! response to drug GO:0042493 143 82 3,000 2,452E-03 0,0203447 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 1,000 2,459E-03 0,02032939 ! neuron fate specification GO:0048665 17 11 1,000 2,459E-03 0,02025977 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,459E-03 0,02019063 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,459E-03 0,02012195 ! blood vessel remodeling GO:0001974 29 11 1,000 2,459E-03 0,02005374 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,459E-03 0,01998599 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,459E-03 0,0199187 ! ventral spinal cord development GO:0021517 21 11 1,000 2,459E-03 0,01985186 ! negative regulation of proteolysis GO:0045861 25 11 1,000 2,459E-03 0,01978546 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 1,000 2,459E-03 0,01971951 ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 1,000 2,459E-03 0,019654 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 1,000 2,459E-03 0,01958892 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 2,459E-03 0,01952427 ! nitric oxide metabolic process GO:0046209 15 11 1,000 2,459E-03 0,01946004 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 2,459E-03 0,01939624 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 24 11 1,000 2,459E-03 0,01933286 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 2,459E-03 0,01926988 ! oocyte differentiation GO:0009994 18 11 1,000 2,459E-03 0,01920732 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 2,459E-03 0,01914516 ! cytokinesis GO:0000910 72 40 2,000 2,586E-03 0,02007102 ! negative regulation of growth GO:0045926 155 84 3,000 2,677E-03 0,02070771 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,776E-03 0,02140926 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,776E-03 0,02134086 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 2,937E-03 0,02250676 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,937E-03 0,02243531 ! hippocampus development GO:0021766 26 12 1,000 2,937E-03 0,02236431 ! entry into host cell GO:0030260 32 12 1,000 2,937E-03 0,02229376 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,937E-03 0,02222365 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 2,937E-03 0,02215399 ! focal adhesion formation GO:0048041 35 12 1,000 2,937E-03 0,02208476 ! asymmetric protein localization GO:0008105 20 12 1,000 2,937E-03 0,02201596 ! membrane protein proteolysis GO:0033619 25 12 1,000 2,937E-03 0,02194758 GO:0006509|membrane protein ectodomain proteolysis, ! histone acetylation GO:0016573 26 12 1,000 2,937E-03 0,02187964 ! autonomic nervous system development GO:0048483 24 12 1,000 2,937E-03 0,02181211 ! gland morphogenesis GO:0022612 29 12 1,000 2,937E-03 0,02174499 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,937E-03 0,02167829 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,937E-03 0,02161199 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,937E-03 0,0215461 ! response to cold GO:0009409 17 12 1,000 2,937E-03 0,02148061 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 2,975E-03 0,02168965 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of protein modification process GO:0031401 136 88 3,000 3,167E-03 0,02302182 ! regulation of DNA binding GO:0051101 155 88 3,000 3,167E-03 0,02295248 ! gland development GO:0048732 206 88 3,000 3,167E-03 0,02288355 ! epithelial cell differentiation GO:0030855 79 43 2,000 3,182E-03 0,02292212 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 3,299E-03 0,02369181 ! male sex differentiation GO:0046661 76 44 2,000 3,398E-03 0,02433088 ! double-strand break repair GO:0006302 81 44 2,000 3,398E-03 0,02425869 ! developmental growth GO:0048589 82 44 2,000 3,398E-03 0,02418691 ! sex differentiation GO:0007548 145 90 3,000 3,434E-03 0,02437206 ! regulation of chemokine production GO:0032642 18 13 1,000 3,456E-03 0,02445453 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 3,456E-03 0,02438282 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 22 13 1,000 3,456E-03 0,02431152 ! deoxyribonucleotide catabolic process GO:0009264 19 13 1,000 3,456E-03 0,02424064 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 3,456E-03 0,02417018 ! exocrine system development GO:0035272 32 13 1,000 3,456E-03 0,02410012 ! regulation of cellular pH GO:0030641 22 13 1,000 3,456E-03 0,02403046 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,456E-03 0,02396121 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 3,456E-03 0,02389236 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 3,456E-03 0,0238239 ! regulation of mRNA stability GO:0043488 31 13 1,000 3,456E-03 0,02375583 ! embryonic placenta development GO:0001892 23 13 1,000 3,456E-03 0,02368815 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 3,456E-03 0,02362085 ! response to insulin stimulus GO:0032868 95 46 2,000 3,856E-03 0,02628036 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 3,862E-03 0,02624984 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,014E-03 0,02720212 ! regulation of S phase GO:0033261 23 14 1,000 4,014E-03 0,02712571 ! regulation of mRNA processing GO:0050684 24 14 1,000 4,014E-03 0,02704973 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 4,014E-03 0,02697417 ! bone mineralization GO:0030282 17 14 1,000 4,014E-03 0,02689904 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 4,014E-03 0,02682432 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 4,014E-03 0,02675001 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,014E-03 0,02667611 ! regulation of RNA stability GO:0043487 32 14 1,000 4,014E-03 0,02660263 ! positive regulation of DNA binding GO:0043388 73 47 2,000 4,098E-03 0,02708813 ! leukocyte differentiation GO:0002521 202 96 3,000 4,325E-03 0,02851087 ! activation of caspase activity GO:0006919 84 48 2,000 4,35E-03 0,02859288 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 4,35E-03 0,02851497 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 4,488E-03 0,0293395 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 4,61E-03 0,03005949 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 4,61E-03 0,02997825 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 4,61E-03 0,0298987 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 4,61E-03 0,02981833 ! glycoprotein catabolic process GO:0006516 26 15 1,000 4,61E-03 0,02973839 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 4,61E-03 0,02965887 ! G1/S transition checkpoint GO:0031575 40 15 1,000 4,61E-03 0,02957978 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 4,61E-03 0,02950111 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 4,61E-03 0,02942286 ! dopamine metabolic process GO:0042417 35 15 1,000 4,61E-03 0,02934502 ! regulation of cell projection organization GO:0031344 121 50 2,000 4,88E-03 0,03097935 ! positive regulation of binding GO:0051099 78 51 2,000 5,159E-03 0,03266548 ! response to estrogen stimulus GO:0043627 93 51 2,000 5,159E-03 0,03257974 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 5,159E-03 0,03249445 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 5,245E-03 0,03295093 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 5,245E-03 0,03286512 ! activation of MAPKK activity GO:0000186 35 16 1,000 5,245E-03 0,03277975 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 5,245E-03 0,03269483 GO:0031114|regulation of microtubule depolymerization, ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 5,245E-03 0,03261035 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 5,245E-03 0,0325263 ! biomineral formation GO:0031214 20 16 1,000 5,245E-03 0,03244269 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 5,245E-03 0,0323595 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 5,245E-03 0,03227674 ! defense response to virus GO:0051607 37 16 1,000 5,245E-03 0,0321944 ! regulation of muscle contraction GO:0006937 81 52 2,000 5,448E-03 0,03335187 ! membrane fusion GO:0006944 110 52 2,000 5,448E-03 0,03326722 ! cartilage development GO:0051216 90 52 2,000 5,448E-03 0,033183 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 5,918E-03 0,03595657 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 5,918E-03 0,035866 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 1,000 5,918E-03 0,03577588 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 41 17 1,000 5,918E-03 0,03568622 ! limbic system development GO:0021761 36 17 1,000 5,918E-03 0,035597 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 5,918E-03 0,03550823 ! regulation of viral genome replication GO:0045069 28 17 1,000 5,918E-03 0,0354199 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 5,918E-03 0,03533201 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 5,918E-03 0,03524456 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,918E-03 0,03515753 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 5,918E-03 0,03507094 ! DNA unwinding during replication GO:0006268 27 17 1,000 5,918E-03 0,03498477 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,918E-03 0,03489902 ! neural crest cell migration GO:0001755 37 17 1,000 5,918E-03 0,03481369 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 5,918E-03 0,03472878 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 5,918E-03 0,03464428 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 5,918E-03 0,0345602 ! positive regulation of caspase activity GO:0043280 95 55 2,000 6,371E-03 0,03711543 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 6,371E-03 0,03702578 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 6,628E-03 0,03842627 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,628E-03 0,0383339 ! centrosome cycle GO:0007098 25 18 1,000 6,628E-03 0,03824197 ! cell-substrate junction assembly GO:0007044 54 18 1,000 6,628E-03 0,03815049 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 6,628E-03 0,03805943 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 6,628E-03 0,03796882 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 6,628E-03 0,03787863 ! nucleotide-excision repair GO:0006289 83 56 2,000 6,698E-03 0,03818915 ! regulation of DNA replication GO:0006275 101 56 2,000 6,698E-03 0,03809887 ! regulation of bone remodeling GO:0046850 137 57 2,000 7,035E-03 0,03992126 ! positive regulation of translation GO:0045727 30 19 1,000 7,375E-03 0,04174876 ! lipid phosphorylation GO:0046834 35 19 1,000 7,375E-03 0,04165076 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 7,375E-03 0,04155322 ! pigmentation during development GO:0048066 41 19 1,000 7,375E-03 0,04145613 ! actin filament bundle formation GO:0051017 42 19 1,000 7,375E-03 0,0413595 ! neuromuscular junction development GO:0007528 34 19 1,000 7,375E-03 0,04126331 ! response to lipopolysaccharide GO:0032496 30 19 1,000 7,375E-03 0,04116757 ! plasma membrane fusion GO:0045026 28 19 1,000 7,375E-03 0,04107228 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 7,375E-03 0,04097742 ! prostaglandin metabolic process GO:0006693 37 19 1,000 7,375E-03 0,040883 GO:0006692|prostanoid metabolic process, ! cellular pigmentation GO:0033059 36 19 1,000 7,375E-03 0,04078902 ! cell-cell junction organization GO:0045216 35 19 1,000 7,375E-03 0,04069547 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 7,375E-03 0,04060234 ! proximal/distal pattern formation GO:0009954 32 19 1,000 7,375E-03 0,04050964 ! peptide hormone secretion GO:0030072 31 19 1,000 7,375E-03 0,04041737 ! regulation of tissue remodeling GO:0034103 140 58 2,000 7,382E-03 0,0403664 ! DNA catabolic process GO:0006308 86 59 2,000 7,739E-03 0,04222174 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 8,106E-03 0,04412326 ! regulation of heart contraction GO:0008016 110 60 2,000 8,106E-03 0,04402366 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 8,106E-03 0,04392451 ! kidney development GO:0001822 122 60 2,000 8,106E-03 0,0438258 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 8,157E-03 0,04400558 ! protein amino acid acetylation GO:0006473 39 20 1,000 8,157E-03 0,04390713 ! response to alkaloid GO:0043279 38 20 1,000 8,157E-03 0,04380913 ! DNA duplex unwinding GO:0032508 31 20 1,000 8,157E-03 0,04371156 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 1,000 8,157E-03 0,04361442 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 8,157E-03 0,04351771 ! D-ribose metabolic process GO:0006014 29 20 1,000 8,157E-03 0,04342144 ! peptide secretion GO:0002790 35 20 1,000 8,157E-03 0,04332558 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 8,157E-03 0,04323015 ! peptidyl-serine modification GO:0018209 43 20 1,000 8,157E-03 0,04313514 ! negative regulation of T cell activation GO:0050868 40 20 1,000 8,157E-03 0,04304055 ! negative regulation of translation GO:0017148 29 20 1,000 8,157E-03 0,04294637 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 8,157E-03 0,0428526 ! regulation of protein complex assembly GO:0043254 117 61 2,000 8,483E-03 0,04446503 ! mesoderm development GO:0007498 119 61 2,000 8,483E-03 0,04436836 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 8,483E-03 0,04427212 ! hormone secretion GO:0046879 38 21 1,000 8,976E-03 0,04674337 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 8,976E-03 0,04664241 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 8,976E-03 0,04654189 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 8,976E-03 0,0464418 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 8,976E-03 0,04634214 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 8,976E-03 0,0462429 ! oogenesis GO:0048477 36 21 1,000 8,976E-03 0,0461441 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 8,976E-03 0,04604571 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 8,976E-03 0,04594774 ! collagen catabolic process GO:0030574 28 21 1,000 8,976E-03 0,04585018 ! gut development GO:0048565 39 21 1,000 8,976E-03 0,04575304 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 9,267E-03 0,047139 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 9,267E-03 0,04703955 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 9,829E-03 0,04978698 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 9,829E-03 0,04968239 ! deoxyribonucleotide metabolic process GO:0009262 32 22 1,000 9,829E-03 0,04957823 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 9,829E-03 0,04947451 ! ureteric bud development GO:0001657 43 22 1,000 9,829E-03 0,04937123 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 9,829E-03 0,04926837 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 9,829E-03 0,04916594 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 9,829E-03 0,04906394 ! protein stabilization GO:0050821 39 22 1,000 9,829E-03 0,04896236 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 0,01009257 0,05017093 ! germ cell development GO:0007281 118 65 2,000 0,01009257 0,05006748 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01071712 0,05305637 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 0,01071712 0,05294743 ! gluconeogenesis GO:0006094 33 23 1,000 0,01071712 0,05283893 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 0,01071712 0,05273087 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 0,01071712 0,05262326 ! regulation of viral reproduction GO:0050792 38 23 1,000 0,01071712 0,05251608 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 0,01071712 0,05240934 ! platelet activation GO:0030168 37 23 1,000 0,01071712 0,05230304 ! hormone transport GO:0009914 40 23 1,000 0,01071712 0,05219716 ! lung development GO:0030324 144 67 2,000 0,01095941 0,05326939 ! homeostasis of number of cells GO:0048872 114 67 2,000 0,01095941 0,05316199 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 0,01140847 0,05522895 ! viral reproduction GO:0016032 134 68 2,000 0,01140847 0,05511805 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01163922 0,05612015 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01163922 0,05600791 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01163922 0,05589611 ! spinal cord development GO:0021510 47 24 1,000 0,01163922 0,05578477 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 0,01163922 0,05567386 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 0,01163922 0,0555634 ! pallium development GO:0021543 49 24 1,000 0,01163922 0,05545337 ! pentose metabolic process GO:0019321 35 24 1,000 0,01163922 0,05534378 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01163922 0,05523462 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01163922 0,05512589 ! protein tetramerization GO:0051262 52 24 1,000 0,01163922 0,05501759 ! respiratory tube development GO:0030323 150 70 2,000 0,01233808 0,05820672 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 0,01259488 0,05930191 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01259488 0,05918608 ! myelination GO:0042552 45 25 1,000 0,01259488 0,05907071 ! receptor metabolic process GO:0043112 46 25 1,000 0,01259488 0,05895579 ! chromosome condensation GO:0030261 45 25 1,000 0,01259488 0,05884131 ! response to starvation GO:0042594 42 25 1,000 0,01259488 0,05872727 ! neural crest cell development GO:0014032 54 25 1,000 0,01259488 0,05861368 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 0,01259488 0,05850053 ! somitogenesis GO:0001756 43 25 1,000 0,01259488 0,05838781 ! positive regulation of protein secretion GO:0050714 36 25 1,000 0,01259488 0,05827553 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01259488 0,05816367 ! respiratory system development GO:0060541 153 72 2,000 0,01330991 0,06134799 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01358361 0,06248979 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01358361 0,06237054 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01358361 0,06225174 ! initiation of viral infection GO:0019059 57 26 1,000 0,01358361 0,06213339 ! pyruvate metabolic process GO:0006090 38 26 1,000 0,01358361 0,06201549 ! molting cycle process GO:0022404 50 26 1,000 0,01358361 0,06189803 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01358361 0,06178103 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01358361 0,06166446 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01358361 0,06154833 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 0,01358361 0,06143264 ! meiosis GO:0007126 121 74 2,000 0,01432423 0,06466058 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 2,000 0,01432423 0,06453949 ! neuron fate commitment GO:0048663 48 27 1,000 0,01460492 0,06568118 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01460492 0,06555865 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01460492 0,06543656 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 0,01460492 0,06531493 ! male gonad development GO:0008584 44 27 1,000 0,01460492 0,06519375 ! response to toxin GO:0009636 47 27 1,000 0,01460492 0,06507303 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01460492 0,06495274 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01460492 0,0648329 ! cell-matrix adhesion GO:0007160 163 75 2,000 0,01484738 0,06578785 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01484738 0,06566692 ! meiotic cell cycle GO:0051321 122 75 2,000 0,01484738 0,06554643 ! circadian rhythm GO:0007623 50 28 1,000 0,01565832 0,06899985 ! dendrite development GO:0016358 59 28 1,000 0,01565832 0,0688737 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01565832 0,06874802 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01565832 0,0686228 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01592582 0,06966824 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01648115 0,07196669 ! icosanoid biosynthetic process GO:0046456 54 29 1,000 0,01674333 0,07297907 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01674333 0,0728471 ! catechol metabolic process GO:0009712 54 29 1,000 0,01674333 0,07271561 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01674333 0,07258459 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01674333 0,07245404 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01674333 0,07232396 ! tissue homeostasis GO:0001894 48 29 1,000 0,01674333 0,07219435 GO:0048871|multicellular organismal homeostasis, ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,01704724 0,07337327 ! muscle cell differentiation GO:0042692 159 80 2,000 0,01762411 0,07572071 ! phenol metabolic process GO:0018958 55 30 1,000 0,01785947 0,07659515 ! cell junction assembly GO:0034329 78 30 1,000 0,01785947 0,07645886 ! acute-phase response GO:0006953 49 30 1,000 0,01785947 0,07632306 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01785947 0,07618773 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01785947 0,07605289 ! response to hypoxia GO:0001666 171 81 2,000 0,01821177 0,07741609 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01821177 0,07727956 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01821177 0,0771435 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01881023 0,07953851 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01900627 0,08022645 ! collagen metabolic process GO:0032963 45 31 1,000 0,01900627 0,08008595 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01900627 0,07994594 ! peptide transport GO:0015833 55 31 1,000 0,01900627 0,07980642 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01900627 0,07966738 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01900627 0,07952883 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01900627 0,07939076 GO:0043433|negative regulation of transcription factor activity, ! response to oxygen levels GO:0070482 176 83 2,000 0,01941951 0,08097633 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,02003962 0,0834175 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,02018326 0,08387032 ! spindle organization GO:0007051 46 32 1,000 0,02018326 0,08372572 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 0,02018326 0,08358161 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,02018326 0,083438 ! peripheral nervous system development GO:0007422 64 32 1,000 0,02018326 0,08329488 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,02018326 0,08315226 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,02018326 0,08301012 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,02067055 0,08486919 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 2,000 0,02131232 0,08735511 ! mitochondrion organization GO:0007005 148 86 2,000 0,02131232 0,08720655 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02138998 0,0873757 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,02138998 0,0872276 ! cell fate specification GO:0001708 52 33 1,000 0,02138998 0,08708001 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,02262597 0,09195621 ! glial cell differentiation GO:0010001 63 34 1,000 0,02262597 0,09180114 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,02262597 0,0916466 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,02262597 0,09149257 ! mismatch repair GO:0006298 46 34 1,000 0,02262597 0,09133906 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 0,02262597 0,09118606 ! placenta development GO:0001890 53 34 1,000 0,02262597 0,09103358 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,02262597 0,0908816 ! regulation of neurological system process GO:0031644 148 88 2,000 0,02262838 0,09073982 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,02330267 0,09328824 ! negative regulation of secretion GO:0051048 63 35 1,000 0,02389078 0,09548374 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,02389078 0,09532539 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,02389078 0,09516757 ! female gonad development GO:0008585 58 35 1,000 0,02389078 0,09501027 ! telencephalon development GO:0021537 68 35 1,000 0,02389078 0,09485348 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02389078 0,09469722 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,02389078 0,09454147 ! ossification GO:0001503 188 90 2,000 0,0239878 0,09476954 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,0239878 0,09461418 ! bone development GO:0060348 189 91 2,000 0,02468376 0,09719989 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02518396 0,09900752 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02518396 0,09884601 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,02518396 0,09868502 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02518396 0,09852456 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02518396 0,09836462 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02518396 0,09820519 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,02518396 0,09804628 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02518396 0,09788789 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,02610817 0,10131652 ! meiosis I GO:0007127 65 37 1,000 0,02650507 0,10269113 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02650507 0,10252603 ! tissue remodeling GO:0048771 76 37 1,000 0,02650507 0,10236146 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02650507 0,10219742 ! regulation of protein stability GO:0031647 73 37 1,000 0,02650507 0,1020339 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02650507 0,10187091 ! regulation of T cell activation GO:0050863 158 94 2,000 0,02683659 0,1029806 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,02757582 0,10564876 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02785366 0,10654358 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02785366 0,10637446 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 1,000 0,02785366 0,10620588 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02785366 0,10603784 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02785366 0,10587032 ! glucan metabolic process GO:0044042 62 38 1,000 0,02785366 0,10570333 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,02922931 0,11074918 ! ear morphogenesis GO:0042471 60 39 1,000 0,02922931 0,11057505 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02922931 0,11040146 ! segmentation GO:0035282 67 39 1,000 0,02922931 0,11022842 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02922931 0,11005592 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,02922931 0,10988396 ! response to virus GO:0009615 160 98 2,000 0,0298582 0,11207305 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,03063159 0,1147969 ! negative regulation of binding GO:0051100 72 40 1,000 0,03063159 0,11461837 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,03063159 0,11444039 ! maintenance of protein location GO:0045185 91 40 1,000 0,03063159 0,11426296 ! gliogenesis GO:0042063 88 41 1,000 0,03206007 0,11940639 ! T cell differentiation GO:0030217 81 41 1,000 0,03206007 0,11922184 ! female gamete generation GO:0007292 61 41 1,000 0,03206007 0,11903785 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,03351433 0,12424573 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03351433 0,12405458 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,03351433 0,12386402 ! regulation of protein secretion GO:0050708 71 42 1,000 0,03351433 0,12367404 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,03351433 0,12348465 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0337375 0,12411685 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0337375 0,12392736 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0337375 0,12373844 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0337375 0,12355011 ! neuron fate determination GO:0048664 7 5 0,000 0,0337375 0,12336234 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0337375 0,12317514 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0337375 0,12298851 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0337375 0,12280245 ! polyol transport GO:0015791 12 5 0,000 0,0337375 0,12261695 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0337375 0,12243201 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0337375 0,12224762 ! response to superoxide GO:0000303 10 5 0,000 0,0337375 0,12206379 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0337375 0,12188051 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0337375 0,12169778 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0337375 0,1215156 ! female meiosis GO:0007143 7 5 0,000 0,0337375 0,12133396 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0337375 0,12115287 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0337375 0,12097231 ! cobalt ion transport GO:0006824 11 5 0,000 0,0337375 0,12079229 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0337375 0,12061281 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0337375 0,12043386 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0337375 0,12025544 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0337375 0,12007754 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0337375 0,11990018 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0337375 0,11972333 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0337375 0,11954701 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0337375 0,11937121 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0337375 0,11919592 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0337375 0,11902114 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0337375 0,11884688 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0337375 0,11867313 ! negative chemotaxis GO:0050919 14 5 0,000 0,0337375 0,11849988 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0337375 0,11832714 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0337375 0,11815491 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0337375 0,11798317 ! behavioral response to pain GO:0048266 9 5 0,000 0,0337375 0,11781193 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0337375 0,11764119 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0337375 0,11747094 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0337375 0,11730118 ! micturition GO:0060073 9 5 0,000 0,0337375 0,11713192 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0337375 0,11696314 ! copulation GO:0007620 9 5 0,000 0,0337375 0,11679485 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0337375 0,11662704 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0337375 0,11645971 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0337375 0,11629287 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0337375 0,11612649 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0337375 0,1159606 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0337375 0,11579518 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0337375 0,11563023 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0337375 0,11546575 ! grooming behavior GO:0007625 6 5 0,000 0,0337375 0,11530173 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0337375 0,11513818 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0337375 0,1149751 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0337375 0,11481247 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0337375 0,11465031 ! lymph vessel development GO:0001945 10 5 0,000 0,0337375 0,1144886 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0337375 0,11432735 ! endochondral ossification GO:0001958 16 5 0,000 0,0337375 0,11416655 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0337375 0,11400621 ! parathyroid gland development GO:0060017 13 5 0,000 0,0337375 0,11384631 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0337375 0,11368686 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0337375 0,11352786 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0337375 0,1133693 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0337375 0,11321119 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0337375 0,11305351 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0337375 0,11289627 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0337375 0,11273947 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0337375 0,11258311 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0337375 0,11242717 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0337375 0,11227167 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0337375 0,1121166 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0337375 0,11196196 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0337375 0,11180774 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0337375 0,11165395 ! histidine catabolic process GO:0006548 6 5 0,000 0,0337375 0,11150058 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0337375 0,11134763 ! valine metabolic process GO:0006573 10 5 0,000 0,0337375 0,1111951 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0337375 0,11104298 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0337375 0,11089128 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0337375 0,11074 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0337375 0,11058913 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0337375 0,11043867 ! polyol catabolic process GO:0046174 7 5 0,000 0,0337375 0,11028861 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0337375 0,11013897 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0337375 0,10998973 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0337375 0,10984089 ! muscle cell migration GO:0014812 8 5 0,000 0,0337375 0,10969246 ! mitochondrial fission GO:0000266 8 5 0,000 0,0337375 0,10954443 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0337375 0,10939679 ! mRNA transcription GO:0009299 9 5 0,000 0,0337375 0,10924956 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0337375 0,10910271 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0337375 0,10895627 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0337375 0,10881021 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0337375 0,10866455 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0337375 0,10851928 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0337375 0,10837439 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0337375 0,10822989 ! response to food GO:0032094 6 5 0,000 0,0337375 0,10808578 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0337375 0,10794205 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0337375 0,1077987 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0337375 0,10765573 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0337375 0,10751314 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0337375 0,10737093 ! forebrain neuron development GO:0021884 13 5 0,000 0,0337375 0,10722909 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0337375 0,10708763 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0337375 0,10694653 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0337375 0,10680582 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0337375 0,10666547 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0337375 0,10652549 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0337375 0,10638587 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0337375 0,10624662 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0337375 0,10610774 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0337375 0,10596922 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0337375 0,10583106 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0337375 0,10569325 ! basic amino acid transport GO:0015802 11 5 0,000 0,0337375 0,10555581 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0337375 0,10541873 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0337375 0,105282 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0337375 0,10514562 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0337375 0,1050096 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0337375 0,10487393 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0337375 0,10473861 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0337375 0,10460363 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0337375 0,10446901 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0337375 0,10433473 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0337375 0,1042008 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0337375 0,1040672 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0337375 0,10393396 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0337375 0,10380105 ! response to arsenic GO:0046685 10 5 0,000 0,0337375 0,10366848 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0337375 0,10353625 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0337375 0,10340436 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0337375 0,1032728 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0337375 0,10314158 ! response to cadmium ion GO:0046686 7 5 0,000 0,0337375 0,10301069 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0337375 0,10288013 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0337375 0,1027499 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0337375 0,10262 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0337375 0,10249043 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0337375 0,10236119 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0337375 0,10223227 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0337375 0,10210367 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0337375 0,1019754 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0337375 0,10184745 ! neural tube patterning GO:0021532 7 5 0,000 0,0337375 0,10171982 ! embryonic cleavage GO:0040016 6 5 0,000 0,0337375 0,10159252 ! peroxisome fission GO:0016559 5 5 0,000 0,0337375 0,10146552 ! histone demethylation GO:0016577 10 5 0,000 0,0337375 0,10133885 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0337375 0,10121249 ! mitotic recombination GO:0006312 9 5 0,000 0,0337375 0,10108645 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0337375 0,10096072 ! metaphase plate congression GO:0051310 7 5 0,000 0,0337375 0,1008353 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0337375 0,1007102 GO:0032374|regulation of cholesterol transport, ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0337375 0,1005854 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0337375 0,10046092 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0337375 0,10033674 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0337375 0,10021286 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0337375 0,1000893 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0337375 0,09996603 ! plasminogen activation GO:0031639 5 5 0,000 0,0337375 0,09984307 ! B cell homeostasis GO:0001782 13 5 0,000 0,0337375 0,09972042 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0337375 0,09959806 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0337375 0,099476 ! metaphase GO:0051323 8 5 0,000 0,0337375 0,09935425 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0337375 0,09923279 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0337375 0,09911162 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0337375 0,09899076 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0337375 0,09887018 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0337375 0,0987499 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0337375 0,09862991 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0337375 0,09851022 ! response to redox state GO:0051775 5 5 0,000 0,0337375 0,09839081 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0337375 0,09827169 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0337375 0,09815287 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0337375 0,09803432 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0337375 0,09791607 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0337375 0,0977981 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0337375 0,09768041 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0337375 0,097563 GO:0033015|tetrapyrrole catabolic process, ! striatum development GO:0021756 9 5 0,000 0,0337375 0,09744588 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0337375 0,09732904 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0337375 0,09721248 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0337375 0,0970962 ! glial cell migration GO:0008347 11 5 0,000 0,0337375 0,09698019 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0337375 0,09686446 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0337375 0,09674901 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0337375 0,09663383 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0337375 0,09651893 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0337375 0,0964043 ! neuroprotection GO:0043526 6 5 0,000 0,0337375 0,09628994 ! neural plate development GO:0001840 8 5 0,000 0,0337375 0,09617585 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0337375 0,09606204 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0337375 0,09594849 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0337375 0,09583521 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0337375 0,09572219 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0337375 0,09560945 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0337375 0,09549696 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0337375 0,09538475 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0337375 0,09527279 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0337375 0,0951611 ! spindle assembly GO:0051225 6 5 0,000 0,0337375 0,09504967 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0337375 0,0949385 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0337375 0,09482759 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0337375 0,09471694 ! drug metabolic process GO:0017144 6 5 0,000 0,0337375 0,09460655 ! stem cell division GO:0017145 11 5 0,000 0,0337375 0,09449641 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0337375 0,09438653 ! organ regeneration GO:0031100 7 5 0,000 0,0337375 0,09427691 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0337375 0,09416754 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0337375 0,09405842 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0337375 0,09394956 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,03499395 0,09733578 ! glucose transport GO:0015758 65 43 1,000 0,03499395 0,09722339 ! phagocytosis GO:0006909 90 43 1,000 0,03499395 0,09711125 ! hexose transport GO:0008645 67 44 1,000 0,03649853 0,10116989 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 0,03649853 0,10105347 ! B cell differentiation GO:0030183 107 44 1,000 0,03649853 0,10093732 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,03649853 0,10082143 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03649853 0,10070581 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,03802765 0,10480474 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03802765 0,10468483 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,03802765 0,10456519 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,03958092 0,10871199 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,03958092 0,10858803 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04034782 0,1105659 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04034782 0,11044011 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04034782 0,11031461 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04034782 0,1101894 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04034782 0,11006447 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04034782 0,10993982 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04034782 0,10981545 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04034782 0,10969137 ! response to oxygen radical GO:0000305 11 6 0,000 0,04034782 0,10956756 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04034782 0,10944404 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04034782 0,10932079 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04034782 0,10919782 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04034782 0,10907512 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04034782 0,1089527 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04034782 0,10883056 ! forebrain regionalization GO:0021871 8 6 0,000 0,04034782 0,10870869 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04034782 0,10858709 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04034782 0,10846576 ! response to zinc ion GO:0010043 9 6 0,000 0,04034782 0,10834471 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04034782 0,10822392 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04034782 0,10810341 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04034782 0,10798316 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04034782 0,10786318 ! malate metabolic process GO:0006108 11 6 0,000 0,04034782 0,10774346 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04034782 0,10762401 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04034782 0,10750483 ! protein refolding GO:0042026 15 6 0,000 0,04034782 0,10738591 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04034782 0,10726725 ! opsonization GO:0008228 8 6 0,000 0,04034782 0,10714885 ! mating behavior GO:0007617 7 6 0,000 0,04034782 0,10703072 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,04034782 0,10691284 ! equilibrioception GO:0050957 14 6 0,000 0,04034782 0,10679522 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04034782 0,10667787 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04034782 0,10656077 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04034782 0,10644392 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04034782 0,10632734 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04034782 0,10621101 ! toxin metabolic process GO:0009404 11 6 0,000 0,04034782 0,10609493 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04034782 0,1059791 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04034782 0,10586353 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04034782 0,10574821 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04034782 0,10563314 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04034782 0,10551833 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04034782 0,10540376 ! thymic T cell selection GO:0045061 12 6 0,000 0,04034782 0,10528944 ! protein lipoylation GO:0009249 10 6 0,000 0,04034782 0,10517536 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04034782 0,10506154 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04034782 0,10494796 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04034782 0,10483462 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04034782 0,10472153 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04034782 0,10460868 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04034782 0,10449608 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,04034782 0,10438372 ! response to pH GO:0009268 10 6 0,000 0,04034782 0,1042716 ! hyperosmotic response GO:0006972 9 6 0,000 0,04034782 0,10415972 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04034782 0,10404808 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04034782 0,10393668 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04034782 0,10382552 ! urea metabolic process GO:0019627 7 6 0,000 0,04034782 0,10371459 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04034782 0,10360391 ! neutrophil activation GO:0042119 8 6 0,000 0,04034782 0,10349345 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04034782 0,10338324 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04034782 0,10327325 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04034782 0,10316351 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04034782 0,10305399 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04034782 0,10294471 ! neuron apoptosis GO:0051402 9 6 0,000 0,04034782 0,10283566 ! nucleoside salvage GO:0043174 9 6 0,000 0,04034782 0,10272684 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04034782 0,10261824 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,04034782 0,10250988 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04034782 0,10240175 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04034782 0,10229385 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,04034782 0,10218617 ! carnitine transport GO:0015879 10 6 0,000 0,04034782 0,10207872 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04034782 0,10197149 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04034782 0,10186449 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04034782 0,10175771 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04034782 0,10165116 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04034782 0,10154483 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04034782 0,10143872 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04034782 0,10133284 ! monocyte differentiation GO:0030224 12 6 0,000 0,04034782 0,10122717 ! neural nucleus development GO:0048857 14 6 0,000 0,04034782 0,10112173 ! astrocyte development GO:0014002 15 6 0,000 0,04034782 0,1010165 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04034782 0,1009115 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04034782 0,10080671 ! interaction with symbiont GO:0051702 13 6 0,000 0,04034782 0,10070214 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04034782 0,10059778 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04034782 0,10049364 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04034782 0,10038972 ! response to copper ion GO:0046688 10 6 0,000 0,04034782 0,10028601 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04034782 0,10018252 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,04034782 0,10007924 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04034782 0,09997617 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04034782 0,09987331 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04034782 0,09977067 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04034782 0,09966823 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04034782 0,09956601 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04034782 0,099464 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04034782 0,09936219 ! Schwann cell development GO:0014044 15 6 0,000 0,04034782 0,09926059 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04034782 0,0991592 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04034782 0,09905802 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,04034782 0,09895704 ! subpallium development GO:0021544 10 6 0,000 0,04034782 0,09885627 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04034782 0,09875571 ! histone ubiquitination GO:0016574 8 6 0,000 0,04034782 0,09865534 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04034782 0,09855519 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04034782 0,09845523 ! G2 phase GO:0051319 16 6 0,000 0,04034782 0,09835548 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04034782 0,09825593 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04034782 0,09815658 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04034782 0,09805743 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04034782 0,09795849 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04034782 0,09785974 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04034782 0,09776119 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04034782 0,09766284 ! receptor internalization GO:0031623 10 6 0,000 0,04034782 0,09756468 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04034782 0,09746673 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,04034782 0,09736897 ! protein destabilization GO:0031648 9 6 0,000 0,04034782 0,0972714 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04034782 0,09717403 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04034782 0,09707686 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04034782 0,09697988 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04034782 0,09688309 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04034782 0,0967865 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04034782 0,0966901 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04034782 0,09659389 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04034782 0,09649787 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04034782 0,09640204 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04034782 0,09630641 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04034782 0,09621096 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04034782 0,0961157 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04034782 0,09602063 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04034782 0,09592575 ! catecholamine transport GO:0051937 9 6 0,000 0,04034782 0,09583106 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04034782 0,09573655 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04034782 0,09564223 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04034782 0,09554809 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04034782 0,09545414 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04034782 0,09536037 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,04034782 0,09526679 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04034782 0,09517339 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04034782 0,09508018 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04034782 0,09498714 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04034782 0,09489429 ! endosome transport GO:0016197 108 47 1,000 0,04115794 0,09670507 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,04115794 0,09661073 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,04115794 0,09651656 ! methylation GO:0032259 90 47 1,000 0,04115794 0,09642258 ! protein homooligomerization GO:0051260 76 47 1,000 0,04115794 0,09632879 ! mitochondrial transport GO:0006839 82 48 1,000 0,0427583 0,09997714 ! Notch signaling pathway GO:0007219 96 48 1,000 0,0427583 0,09988007 ! cellular component disassembly GO:0022411 86 48 1,000 0,0427583 0,09978319 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,0427583 0,0996865 ! regulation of action potential GO:0001508 95 49 1,000 0,04438163 0,10337095 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,04438163 0,10327098 ! response to temperature stimulus GO:0009266 76 49 1,000 0,04438163 0,1031712 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,04438163 0,10307162 ! endocrine system development GO:0035270 104 49 1,000 0,04438163 0,10297222 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,04438163 0,10287302 ! neuromuscular process GO:0050905 99 50 1,000 0,04602753 0,10658541 ! regulation of ossification GO:0030278 117 50 1,000 0,04602753 0,10648292 ! histone modification GO:0016570 91 50 1,000 0,04602753 0,10638063 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,04602753 0,10627854 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,04602753 0,10617664 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,04602753 0,10607494 ! tRNA transcription GO:0009304 14 7 0,000 0,04691314 0,10801246 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04691314 0,1079092 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04691314 0,10780613 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04691314 0,10770326 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04691314 0,10760059 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04691314 0,10749811 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04691314 0,10739583 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04691314 0,10729374 ! prostate gland development GO:0030850 13 7 0,000 0,04691314 0,10719185 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04691314 0,10709015 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04691314 0,10698864 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04691314 0,10688733 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04691314 0,10678621 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04691314 0,10668527 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04691314 0,10658453 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04691314 0,10648398 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04691314 0,10638362 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04691314 0,10628345 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04691314 0,10618346 ! glycolipid transport GO:0046836 10 7 0,000 0,04691314 0,10608366 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04691314 0,10598406 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04691314 0,10588463 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04691314 0,1057854 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04691314 0,10568635 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04691314 0,10558748 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04691314 0,1054888 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04691314 0,10539031 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04691314 0,105292 ! pericardium development GO:0060039 14 7 0,000 0,04691314 0,10519387 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04691314 0,10509592 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04691314 0,10499816 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04691314 0,10490058 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04691314 0,10480317 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04691314 0,10470595 ! lipoprotein transport GO:0042953 14 7 0,000 0,04691314 0,10460891 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04691314 0,10451205 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04691314 0,10441537 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04691314 0,10431887 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04691314 0,10422255 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04691314 0,1041264 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04691314 0,10403043 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04691314 0,10393464 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04691314 0,10383902 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04691314 0,10374358 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04691314 0,10364832 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04691314 0,10355323 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04691314 0,10345831 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04691314 0,10336357 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04691314 0,103269 ! spinal cord patterning GO:0021511 13 7 0,000 0,04691314 0,10317461 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04691314 0,10308038 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04691314 0,10298633 ! adrenal gland development GO:0030325 17 7 0,000 0,04691314 0,10289245 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04691314 0,10279874 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04691314 0,1027052 ! ovulation GO:0030728 9 7 0,000 0,04691314 0,10261184 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04691314 0,10251864 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04691314 0,10242561 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04691314 0,10233275 ! microtubule nucleation GO:0007020 20 7 0,000 0,04691314 0,10224005 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04691314 0,10214753 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04691314 0,10205517 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04691314 0,10196298 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04691314 0,10187096 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04691314 0,1017791 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04691314 0,1016874 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04691314 0,10159588 ! galactose metabolic process GO:0006012 13 7 0,000 0,04691314 0,10150451 ! vesicle fusion GO:0006906 17 7 0,000 0,04691314 0,10141331 ! response to dietary excess GO:0002021 8 7 0,000 0,04691314 0,10132228 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04691314 0,10123141 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04691314 0,1011407 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04691314 0,10105015 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04691314 0,10095977 ! organ growth GO:0035265 15 7 0,000 0,04691314 0,10086954 ! purine salvage GO:0043101 10 7 0,000 0,04691314 0,10077948 ! nucleoside transport GO:0015858 8 7 0,000 0,04691314 0,10068958 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04691314 0,10059984 ! parturition GO:0007567 14 7 0,000 0,04691314 0,10051026 ! rRNA modification GO:0000154 14 7 0,000 0,04691314 0,10042084 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04691314 0,10033157 ! spindle checkpoint GO:0031577 15 7 0,000 0,04691314 0,10024247 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04691314 0,10015352 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04691314 0,10006473 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04691314 0,0999761 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04691314 0,09988763 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04691314 0,09979931 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04691314 0,09971115 ! fibrinolysis GO:0042730 10 7 0,000 0,04691314 0,09962314 ! eating behavior GO:0042755 7 7 0,000 0,04691314 0,09953529 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04691314 0,09944759 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04691314 0,09936005 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04691314 0,09927266 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04691314 0,09918543 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04691314 0,09909835 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04691314 0,09901142 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04691314 0,09892464 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04691314 0,09883802 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04691314 0,09875155 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04691314 0,09866523 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04691314 0,09857906 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04691314 0,09849304 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04691314 0,09840717 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04691314 0,09832145 ! regulation of meiosis GO:0040020 12 7 0,000 0,04691314 0,09823587 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04691314 0,09815045 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04691314 0,09806518 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04691314 0,09798005 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04691314 0,09789507 ! transcription termination GO:0006353 13 7 0,000 0,04691314 0,09781024 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04691314 0,09772556 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04691314 0,09764102 ! anaphase GO:0051322 17 7 0,000 0,04691314 0,09755663 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04691314 0,09747238 ! axonal fasciculation GO:0007413 18 7 0,000 0,04691314 0,09738828 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04691314 0,09730433 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04691314 0,09722052 ! diuresis GO:0030146 12 7 0,000 0,04691314 0,09713685 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04691314 0,09705333 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04691314 0,09696995 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04691314 0,09688671 ! antibiotic transport GO:0042891 9 7 0,000 0,04691314 0,09680362 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04691314 0,09672067 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04691314 0,09663786 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04691314 0,09655519 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04691314 0,09647267 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04691314 0,09639028 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04691314 0,09630804 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04691314 0,09622593 ! lymph node development GO:0048535 10 7 0,000 0,04691314 0,09614397 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04691314 0,09606214 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04691314 0,09598046 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04691314 0,09589891 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04691314 0,0958175 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04691314 0,09573623 ! adult feeding behavior GO:0008343 9 7 0,000 0,04691314 0,0956551 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04691314 0,09557411 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04691314 0,09549325 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04691314 0,09541253 ! muscle adaptation GO:0043500 14 7 0,000 0,04691314 0,09533194 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04691314 0,09525149 ! retina homeostasis GO:0001895 12 7 0,000 0,04691314 0,09517118 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04691314 0,095091 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04691314 0,09501096 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04691314 0,09493105 ! protein prenylation GO:0018342 18 7 0,000 0,04691314 0,09485128 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04691314 0,09477164 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04691314 0,09469213 ! viral infectious cycle GO:0019058 99 51 1,000 0,04769563 0,09619085 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,04769563 0,09611029 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,04769563 0,09602986 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,04769563 0,09594957 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04938554 0,09926618 ! synapse organization GO:0050808 85 52 1,000 0,04938554 0,09918332 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,0510969 0,10253474 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,05282934 0,10592282 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,05282934 0,10583463 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,05282934 0,10574658 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,05282934 0,10565867 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05343376 0,10677876 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05343376 0,10669015 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05343376 0,10660169 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05343376 0,10651337 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05343376 0,10642519 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05343376 0,10633717 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05343376 0,10624928 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05343376 0,10616155 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05343376 0,10607395 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05343376 0,10598651 ! meiotic prophase I GO:0007128 13 8 0,000 0,05343376 0,1058992 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05343376 0,10581204 ! oligopeptide transport GO:0006857 15 8 0,000 0,05343376 0,10572503 ! UTP metabolic process GO:0046051 8 8 0,000 0,05343376 0,10563815 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05343376 0,10555142 ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05343376 0,10546483 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05343376 0,10537839 ! succinate metabolic process GO:0006105 14 8 0,000 0,05343376 0,10529208 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05343376 0,10520592 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05343376 0,1051199 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05343376 0,10503401 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05343376 0,10494827 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05343376 0,10486267 ! reflex GO:0060004 16 8 0,000 0,05343376 0,10477721 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05343376 0,10469188 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05343376 0,1046067 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05343376 0,10452165 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05343376 0,10443674 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05343376 0,10435197 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,05343376 0,10426734 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05343376 0,10418285 ! pigment granule organization GO:0048753 16 8 0,000 0,05343376 0,10409849 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05343376 0,10401427 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05343376 0,10393018 ! histidine metabolic process GO:0006547 16 8 0,000 0,05343376 0,10384623 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05343376 0,10376242 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05343376 0,10367874 ! glycine catabolic process GO:0006546 13 8 0,000 0,05343376 0,10359519 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05343376 0,10351178 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05343376 0,10342851 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05343376 0,10334536 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,05343376 0,10326236 ! melanin metabolic process GO:0006582 15 8 0,000 0,05343376 0,10317948 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05343376 0,10309674 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05343376 0,10301413 ! macrophage activation GO:0042116 12 8 0,000 0,05343376 0,10293165 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05343376 0,10284931 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05343376 0,10276709 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05343376 0,10268501 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05343376 0,10260306 ! osteoblast development GO:0002076 16 8 0,000 0,05343376 0,10252124 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05343376 0,10243955 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05343376 0,10235799 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05343376 0,10227656 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05343376 0,10219526 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05343376 0,10211408 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05343376 0,10203304 ! response to UV-B GO:0010224 16 8 0,000 0,05343376 0,10195213 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05343376 0,10187134 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05343376 0,10179068 ! intermediate filament organization GO:0045109 12 8 0,000 0,05343376 0,10171015 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05343376 0,10162975 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05343376 0,10154947 ! cellular extravasation GO:0045123 12 8 0,000 0,05343376 0,10146932 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05343376 0,1013893 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05343376 0,1013094 ! response to antibiotic GO:0046677 11 8 0,000 0,05343376 0,10122963 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05343376 0,10114999 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05343376 0,10107047 ! response to tropane GO:0014073 15 8 0,000 0,05343376 0,10099107 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05343376 0,1009118 ! melanosome transport GO:0032402 13 8 0,000 0,05343376 0,10083265 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05343376 0,10075363 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05343376 0,10067473 ! mast cell activation GO:0045576 14 8 0,000 0,05343376 0,10059596 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05343376 0,1005173 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05343376 0,10043878 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05343376 0,10036037 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05343376 0,10028208 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05343376 0,10020392 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05343376 0,10012588 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05343376 0,10004796 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05343376 0,09997017 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05343376 0,09989249 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05343376 0,09981493 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05343376 0,0997375 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05343376 0,09966018 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05343376 0,09958298 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05343376 0,09950591 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05343376 0,09942895 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05343376 0,09935211 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05343376 0,09927539 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05343376 0,09919879 ! hormone catabolic process GO:0042447 17 8 0,000 0,05343376 0,09912231 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05343376 0,09904594 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05343376 0,09896969 ! ATP catabolic process GO:0006200 11 8 0,000 0,05343376 0,09889356 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05343376 0,09881755 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05343376 0,09874165 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05343376 0,09866587 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05343376 0,09859021 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05343376 0,09851466 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05343376 0,09843923 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05343376 0,09836391 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05343376 0,09828871 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05343376 0,09821362 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05343376 0,09813865 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05343376 0,09806379 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05343376 0,09798905 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05343376 0,09791442 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05343376 0,0978399 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,05458248 0,09986726 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,05458248 0,09979138 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,05458248 0,0997156 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,05635597 0,10287745 ! lipid modification GO:0030258 97 57 1,000 0,05814946 0,10607096 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,05814946 0,1059906 ! maintenance of location GO:0051235 118 57 1,000 0,05814946 0,10591037 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05990999 0,10903436 ! axon extension GO:0048675 15 9 0,000 0,05990999 0,10895195 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05990999 0,10886966 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05990999 0,10878749 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05990999 0,10870545 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05990999 0,10862353 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05990999 0,10854174 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05990999 0,10846007 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05990999 0,10837852 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05990999 0,10829709 ! phosphate transport GO:0006817 19 9 0,000 0,05990999 0,10821579 ! reproductive behavior GO:0019098 19 9 0,000 0,05990999 0,10813461 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05990999 0,10805354 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05990999 0,10797261 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05990999 0,10789179 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05990999 0,10781109 ! GTP metabolic process GO:0046039 9 9 0,000 0,05990999 0,10773051 ! RNA methylation GO:0001510 15 9 0,000 0,05990999 0,10765006 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05990999 0,10756972 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05990999 0,10748951 ! artery development GO:0060840 24 9 0,000 0,05990999 0,10740941 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05990999 0,10732943 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05990999 0,10724958 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05990999 0,10716984 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05990999 0,10709021 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05990999 0,10701071 ! chemosensory behavior GO:0007635 20 9 0,000 0,05990999 0,10693133 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05990999 0,10685206 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05990999 0,10677291 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05990999 0,10669388 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05990999 0,10661496 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05990999 0,10653616 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05990999 0,10645748 ! protein targeting to ER GO:0045047 22 9 0,000 0,05990999 0,10637891 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05990999 0,10630046 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05990999 0,10622213 ! T cell selection GO:0045058 23 9 0,000 0,05990999 0,10614391 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05990999 0,1060658 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05990999 0,10598782 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05990999 0,10590994 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05990999 0,10583218 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05990999 0,10575453 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05990999 0,105677 ! mannose metabolic process GO:0006013 13 9 0,000 0,05990999 0,10559958 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05990999 0,10552228 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05990999 0,10544508 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05990999 0,105368 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05990999 0,10529104 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05990999 0,10521418 ! ruffle organization GO:0031529 15 9 0,000 0,05990999 0,10513744 ! retinol metabolic process GO:0042572 18 9 0,000 0,05990999 0,10506081 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05990999 0,10498429 ! behavioral fear response GO:0001662 22 9 0,000 0,05990999 0,10490788 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05990999 0,10483158 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05990999 0,1047554 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05990999 0,10467932 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05990999 0,10460336 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05990999 0,1045275 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05990999 0,10445176 ! segment specification GO:0007379 13 9 0,000 0,05990999 0,10437613 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05990999 0,1043006 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05990999 0,10422518 ! response to amine stimulus GO:0014075 13 9 0,000 0,05990999 0,10414988 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05990999 0,10407468 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05990999 0,10399959 ! gas homeostasis GO:0033483 16 9 0,000 0,05990999 0,10392461 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05990999 0,10384973 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05990999 0,10377497 ! renal water homeostasis GO:0003091 14 9 0,000 0,05990999 0,10370031 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05990999 0,10362576 ! icosanoid secretion GO:0032309 15 9 0,000 0,05990999 0,10355131 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05990999 0,10347698 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05990999 0,10340275 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05990999 0,10332862 ! regulation of cell division GO:0051302 15 9 0,000 0,05990999 0,10325461 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05990999 0,10318069 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05990999 0,10310689 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05990999 0,10303319 ! sterol catabolic process GO:0016127 11 9 0,000 0,05990999 0,10295959 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05990999 0,1028861 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05990999 0,10281272 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05990999 0,10273944 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05990999 0,10266626 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05990999 0,10259319 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05990999 0,10252022 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05990999 0,10244736 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05990999 0,10237459 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05990999 0,10230194 ! purine base metabolic process GO:0006144 21 9 0,000 0,05990999 0,10222938 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05990999 0,10215693 ! pigment granule transport GO:0051904 17 9 0,000 0,05990999 0,10208458 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05990999 0,10201233 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05990999 0,10194019 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05990999 0,10186815 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05990999 0,10179621 ! mitochondrion localization GO:0051646 15 9 0,000 0,05990999 0,10172437 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,05996258 0,10174187 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,06179499 0,10477713 ! camera-type eye development GO:0043010 116 60 1,000 0,06364634 0,10784021 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06634212 0,11232873 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06634212 0,11224974 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06634212 0,11217086 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06634212 0,11209209 ! synapsis GO:0007129 13 10 0,000 0,06634212 0,11201343 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06634212 0,11193487 ! N-glycan processing GO:0006491 20 10 0,000 0,06634212 0,11185643 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06634212 0,1117781 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06634212 0,11169988 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06634212 0,11162177 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06634212 0,11154377 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06634212 0,11146587 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06634212 0,11138809 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06634212 0,11131041 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06634212 0,11123284 ! androgen metabolic process GO:0008209 17 10 0,000 0,06634212 0,11115538 ! phospholipid efflux GO:0033700 16 10 0,000 0,06634212 0,11107803 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06634212 0,11100079 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06634212 0,11092365 ! pathogenesis GO:0009405 13 10 0,000 0,06634212 0,11084662 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06634212 0,1107697 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06634212 0,11069288 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06634212 0,11061617 ! endoderm development GO:0007492 16 10 0,000 0,06634212 0,11053956 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06634212 0,11046307 ! arginine catabolic process GO:0006527 13 10 0,000 0,06634212 0,11038667 ! proline metabolic process GO:0006560 13 10 0,000 0,06634212 0,11031039 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06634212 0,11023421 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06634212 0,11015813 ! V(D)J recombination GO:0033151 28 10 0,000 0,06634212 0,11008216 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06634212 0,11000629 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06634212 0,10993053 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06634212 0,10985487 ! B cell proliferation GO:0042100 18 10 0,000 0,06634212 0,10977932 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06634212 0,10970387 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06634212 0,10962852 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06634212 0,10955328 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06634212 0,10947814 ! epithelial cell development GO:0002064 20 10 0,000 0,06634212 0,10940311 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06634212 0,10932817 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06634212 0,10925334 ! macroautophagy GO:0016236 17 10 0,000 0,06634212 0,10917861 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06634212 0,10910399 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06634212 0,10902946 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06634212 0,10895504 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06634212 0,10888072 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06634212 0,1088065 ! brain morphogenesis GO:0048854 23 10 0,000 0,06634212 0,10873238 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06634212 0,10865836 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06634212 0,10858444 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06634212 0,10851063 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06634212 0,10843691 ! response to dsRNA GO:0043331 20 10 0,000 0,06634212 0,10836329 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06634212 0,10828978 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06634212 0,10821636 ! melanosome localization GO:0032400 16 10 0,000 0,06634212 0,10814304 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06634212 0,10806983 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06634212 0,10799671 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06634212 0,10792369 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06634212 0,10785076 ! mRNA cleavage GO:0006379 17 10 0,000 0,06634212 0,10777794 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06634212 0,10770522 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06634212 0,10763259 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06634212 0,10756006 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06634212 0,10748763 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06634212 0,1074153 ! prophase GO:0051324 15 10 0,000 0,06634212 0,10734306 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06634212 0,10727092 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06634212 0,10719888 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,06634212 0,10712693 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06634212 0,10705508 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06634212 0,10698333 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06634212 0,10691168 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06634212 0,10684011 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06634212 0,10676865 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06634212 0,10669728 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06634212 0,10662601 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,06634212 0,10655483 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06634212 0,10648374 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06634212 0,10641275 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06634212 0,10634186 ! activation of innate immune response GO:0002218 12 10 0,000 0,06634212 0,10627106 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06634212 0,10620035 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06634212 0,10612974 ! response to nicotine GO:0035094 20 10 0,000 0,06634212 0,10605922 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06634212 0,1059888 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06634212 0,10591847 ! ear development GO:0043583 103 62 1,000 0,06740451 0,10754327 ! viral reproductive process GO:0022415 126 62 1,000 0,06740451 0,107472 ! regulation of mitosis GO:0007088 105 63 1,000 0,06931065 0,11043803 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,06931065 0,11036495 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,07123439 0,11335314 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of muscle development GO:0048635 20 11 0,000 0,07273045 0,11565728 ! respiratory burst GO:0045730 17 11 0,000 0,07273045 0,11558088 ! telencephalon cell migration GO:0022029 20 11 0,000 0,07273045 0,11550459 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,07273045 0,1154284 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,07273045 0,11535231 ! thyroid gland development GO:0030878 26 11 0,000 0,07273045 0,11527632 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07273045 0,11520043 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07273045 0,11512464 ! response to pain GO:0048265 24 11 0,000 0,07273045 0,11504895 ! T cell proliferation GO:0042098 26 11 0,000 0,07273045 0,11497336 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,07273045 0,11489787 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,07273045 0,11482248 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07273045 0,11474719 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07273045 0,11467199 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,07273045 0,1145969 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07273045 0,1145219 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,07273045 0,114447 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! lipid digestion GO:0044241 18 11 0,000 0,07273045 0,1143722 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,07273045 0,11429749 ! UV protection GO:0009650 19 11 0,000 0,07273045 0,11422288 ! adult heart development GO:0007512 14 11 0,000 0,07273045 0,11414838 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07273045 0,11407396 ! temperature homeostasis GO:0001659 17 11 0,000 0,07273045 0,11399965 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07273045 0,11392543 ! negative regulation of ossification GO:0030279 26 11 0,000 0,07273045 0,11385131 ! regulation of organ growth GO:0046620 13 11 0,000 0,07273045 0,11377728 ! pigment granule localization GO:0051875 20 11 0,000 0,07273045 0,11370335 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,07273045 0,11362952 ! vasoconstriction GO:0042310 18 11 0,000 0,07273045 0,11355578 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07273045 0,11348214 ! embryonic axis specification GO:0000578 18 11 0,000 0,07273045 0,11340859 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07273045 0,11333514 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07273045 0,11326179 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07273045 0,11318852 ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07273045 0,11311536 ! zymogen activation GO:0031638 15 11 0,000 0,07273045 0,11304229 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07273045 0,11296931 ! nucleosome positioning GO:0016584 15 11 0,000 0,07273045 0,11289643 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07273045 0,11282364 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07273045 0,11275094 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07273045 0,11267834 ! acid secretion GO:0046717 18 11 0,000 0,07273045 0,11260583 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07273045 0,11253341 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07273045 0,11246109 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07273045 0,11238886 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,07273045 0,11231673 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,07273045 0,11224468 ! cholesterol efflux GO:0033344 19 11 0,000 0,07273045 0,11217273 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07273045 0,11210087 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07273045 0,1120291 ! germ cell migration GO:0008354 25 11 0,000 0,07273045 0,11195743 ! embryonic gut development GO:0048566 15 11 0,000 0,07273045 0,11188584 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07273045 0,11181435 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07273045 0,11174295 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07273045 0,11167164 ! defense response to fungus GO:0050832 13 11 0,000 0,07273045 0,11160042 ! developmental induction GO:0031128 19 11 0,000 0,07273045 0,11152929 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,07273045 0,11145825 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07273045 0,11138731 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,07273045 0,11131645 ! sequestering of metal ion GO:0051238 14 11 0,000 0,07273045 0,11124568 ! lamellipodium assembly GO:0030032 20 11 0,000 0,07273045 0,11117501 ! regulation of embryonic development GO:0045995 27 11 0,000 0,07273045 0,11110442 ! regulation of synapse organization GO:0050807 17 11 0,000 0,07273045 0,11103392 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,0731754 0,11164237 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,07513336 0,11455695 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,07513336 0,1144844 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,07710794 0,11741881 ! adaptive immune response GO:0002250 119 67 1,000 0,07710794 0,11734454 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07907528 0,12026241 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07907528 0,12018643 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07907528 0,12011056 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07907528 0,12003478 ! virus-host interaction GO:0019048 29 12 0,000 0,07907528 0,1199591 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07907528 0,11988351 ! cartilage condensation GO:0001502 20 12 0,000 0,07907528 0,11980801 ! mating GO:0007618 17 12 0,000 0,07907528 0,11973262 ! protein complex disassembly GO:0043241 27 12 0,000 0,07907528 0,11965731 GO:0043624|cellular protein complex disassembly, ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07907528 0,1195821 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07907528 0,11950699 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07907528 0,11943197 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07907528 0,11935704 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07907528 0,11928221 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07907528 0,11920747 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07907528 0,11913283 ! drug transport GO:0015893 16 12 0,000 0,07907528 0,11905828 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07907528 0,11898382 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07907528 0,11890945 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07907528 0,11883518 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07907528 0,118761 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07907528 0,11868692 ! forebrain cell migration GO:0021885 21 12 0,000 0,07907528 0,11861292 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07907528 0,11853902 ! fear response GO:0042596 26 12 0,000 0,07907528 0,11846521 ! monoamine transport GO:0015844 18 12 0,000 0,07907528 0,11839149 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07907528 0,11831786 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07907528 0,11824433 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07907528 0,11817089 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07907528 0,11809753 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07907528 0,11802427 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07907528 0,1179511 ! protein homotetramerization GO:0051289 21 12 0,000 0,07907528 0,11787802 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07907528 0,11780503 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07907528 0,11773213 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07907528 0,11765932 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07907528 0,1175866 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07907528 0,11751398 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07907528 0,11744144 ! cranial nerve development GO:0021545 20 12 0,000 0,07907528 0,11736899 ! fucose catabolic process GO:0019317 22 12 0,000 0,07907528 0,11729663 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07907528 0,11722435 ! histone methylation GO:0016571 26 12 0,000 0,07907528 0,11715217 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07907528 0,11708008 ! T cell homeostasis GO:0043029 25 12 0,000 0,07907528 0,11700807 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07907528 0,11693616 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07907528 0,11686433 ! spleen development GO:0048536 22 12 0,000 0,07907528 0,11679259 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07907528 0,11672094 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07907528 0,11664937 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07907528 0,1165779 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07907528 0,11650651 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07907528 0,11643521 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07907528 0,11636399 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07907528 0,11629286 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07907528 0,11622182 ! regulation of lipase activity GO:0060191 130 68 1,000 0,07909884 0,11618547 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,07909884 0,11611458 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,08110573 0,11898804 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,08110573 0,11891553 ! appendage morphogenesis GO:0035107 135 70 1,000 0,0831283 0,12180676 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,08516626 0,124717 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,08516626 0,12464114 ! B cell activation GO:0042113 160 71 1,000 0,08516626 0,12456537 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,08516626 0,12448969 ! regulation of immune effector process GO:0002697 137 71 1,000 0,08516626 0,1244141 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08537691 0,12464614 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08537691 0,12457055 ! peroxisomal transport GO:0043574 24 13 0,000 0,08537691 0,12449506 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08537691 0,12441965 ! lipid localization GO:0010876 28 13 0,000 0,08537691 0,12434434 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,08537691 0,12426911 ! organelle fusion GO:0048284 32 13 0,000 0,08537691 0,12419398 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08537691 0,12411894 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08537691 0,12404399 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08537691 0,12396913 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08537691 0,12389436 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08537691 0,12381968 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08537691 0,12374509 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08537691 0,12367059 ! methionine metabolic process GO:0006555 27 13 0,000 0,08537691 0,12359617 ! plasma membrane organization GO:0007009 24 13 0,000 0,08537691 0,12352185 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08537691 0,12344762 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08537691 0,12337348 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,08537691 0,12329942 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08537691 0,12322546 ! cytokine metabolic process GO:0042107 22 13 0,000 0,08537691 0,12315158 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,08537691 0,1230778 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,08537691 0,1230041 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08537691 0,12293049 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08537691 0,12285696 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08537691 0,12278353 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08537691 0,12271018 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08537691 0,12263692 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,08537691 0,12256375 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08537691 0,12249066 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08537691 0,12241766 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08537691 0,12234475 ! ribosome assembly GO:0042255 17 13 0,000 0,08537691 0,12227193 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08537691 0,12219919 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08537691 0,12212654 ! chromatin silencing GO:0006342 26 13 0,000 0,08537691 0,12205398 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08537691 0,1219815 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08537691 0,1219091 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08537691 0,1218368 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08537691 0,12176458 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08537691 0,12169244 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,08537691 0,12162039 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08537691 0,12154843 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,08537691 0,12147655 ! insulin secretion GO:0030073 23 13 0,000 0,08537691 0,12140475 ! actin filament polymerization GO:0030041 24 13 0,000 0,08537691 0,12133304 ! acrosome reaction GO:0007340 18 13 0,000 0,08537691 0,12126142 ! acute inflammatory response GO:0002526 113 72 1,000 0,0872193 0,1238051 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0872193 0,1237321 ! carbohydrate transport GO:0008643 110 72 1,000 0,0872193 0,12365919 ! learning or memory GO:0007611 147 73 1,000 0,08928712 0,12651638 ! regulation of blood pressure GO:0008217 125 73 1,000 0,08928712 0,12644191 ! axon guidance GO:0007411 139 73 1,000 0,08928712 0,12636754 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,09136942 0,12923858 ! eye development GO:0001654 143 74 1,000 0,09136942 0,12916265 ! rRNA transcription GO:0009303 25 14 0,000 0,09163562 0,12946289 ! lactation GO:0007595 26 14 0,000 0,09163562 0,12938692 ! reproductive cellular process GO:0048610 20 14 0,000 0,09163562 0,12931103 ! tRNA modification GO:0006400 20 14 0,000 0,09163562 0,12923523 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,09163562 0,12915953 ! water transport GO:0006833 21 14 0,000 0,09163562 0,12908391 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,09163562 0,12900837 ! non-recombinational repair GO:0000726 25 14 0,000 0,09163562 0,12893293 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,09163562 0,12885757 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,09163562 0,12878231 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,09163562 0,12870713 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,09163562 0,12863204 ! RNA polyadenylation GO:0043631 30 14 0,000 0,09163562 0,12855703 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,09163562 0,12848212 ! palate development GO:0060021 31 14 0,000 0,09163562 0,12840729 ! regulated secretory pathway GO:0045055 23 14 0,000 0,09163562 0,12833254 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,09163562 0,12825789 ! arginine metabolic process GO:0006525 17 14 0,000 0,09163562 0,12818332 ! regulation of heart rate GO:0002027 24 14 0,000 0,09163562 0,12810884 ! organic alcohol transport GO:0015850 29 14 0,000 0,09163562 0,12803444 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,09163562 0,12796013 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,09163562 0,12788591 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,09163562 0,12781177 ! neutral amino acid transport GO:0015804 26 14 0,000 0,09163562 0,12773772 ! L-amino acid transport GO:0015807 30 14 0,000 0,09163562 0,12766376 ! stem cell development GO:0048864 43 14 0,000 0,09163562 0,12758988 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,09163562 0,12751608 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,09163562 0,12744238 ! cerebellum development GO:0021549 21 14 0,000 0,09163562 0,12736875 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,09163562 0,12729521 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,09163562 0,12722176 ! cofactor transport GO:0051181 26 14 0,000 0,09163562 0,12714839 ! NADP metabolic process GO:0006739 24 14 0,000 0,09163562 0,12707511 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,09163562 0,12700191 ! intestinal absorption GO:0050892 25 14 0,000 0,09163562 0,12692879 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,09163562 0,12685576 ! oxygen transport GO:0015671 21 14 0,000 0,09163562 0,12678281 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,09163562 0,12670995 ! male genitalia development GO:0030539 24 14 0,000 0,09163562 0,12663717 ! regulation of axon extension GO:0030516 37 14 0,000 0,09163562 0,12656447 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,09163562 0,12649186 ! rhythmic process GO:0048511 128 75 1,000 0,09346592 0,12894438 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,09346592 0,12887049 ! defense response to bacterium GO:0042742 89 76 1,000 0,09557631 0,13170482 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09785172 0,13476315 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09785172 0,13468606 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,09785172 0,13460905 ! superoxide anion generation GO:0042554 20 15 0,000 0,09785172 0,13453213 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,09785172 0,1344553 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,09785172 0,13437856 ! copper ion transport GO:0006825 20 15 0,000 0,09785172 0,1343019 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,09785172 0,13422533 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,09785172 0,13414885 ! sulfate transport GO:0008272 23 15 0,000 0,09785172 0,13407246 ! response to cAMP GO:0051591 22 15 0,000 0,09785172 0,13399615 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,09785172 0,13391993 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,09785172 0,13384379 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,09785172 0,13376774 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,09785172 0,13369178 ! response to hexose stimulus GO:0009746 22 15 0,000 0,09785172 0,13361591 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,09785172 0,13354012 ! pituitary gland development GO:0021983 29 15 0,000 0,09785172 0,13346442 ! vesicle coating GO:0006901 33 15 0,000 0,09785172 0,1333888 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,09785172 0,13331327 ! regulation of exocytosis GO:0017157 22 15 0,000 0,09785172 0,13323782 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,09785172 0,13316246 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,09785172 0,13308719 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,09785172 0,13301199 ! regulation of vasodilation GO:0042312 26 15 0,000 0,09785172 0,13293689 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,09785172 0,13286187 ! histone deacetylation GO:0016575 20 15 0,000 0,09785172 0,13278693 ! mRNA splice site selection GO:0006376 38 15 0,000 0,09785172 0,13271208 ! tissue regeneration GO:0042246 26 15 0,000 0,09785172 0,13263731 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,09785172 0,13256263 ! water homeostasis GO:0030104 27 15 0,000 0,09785172 0,13248803 ! muscle maintenance GO:0046716 26 15 0,000 0,09785172 0,13241352 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,09785172 0,13233908 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,09785172 0,13226474 ! heme biosynthetic process GO:0006783 29 15 0,000 0,09785172 0,13219047 ! cell killing GO:0001906 29 15 0,000 0,09785172 0,13211629 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,09785172 0,13204219 ! detection of bacterium GO:0016045 18 15 0,000 0,09785172 0,13196818 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,09785172 0,13189425 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,09785172 0,1318204 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,09785172 0,13174663 ! peptide hormone processing GO:0016486 23 15 0,000 0,09785172 0,13167295 ! blood coagulation GO:0007596 146 78 1,000 0,09983767 0,13427023 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,10198808 0,13708565 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,10402548 0,13974612 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,10402548 0,13966814 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,10402548 0,13959024 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,10402548 0,13951243 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,10402548 0,13943471 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,10402548 0,13935707 ! bone remodeling GO:0046849 27 16 0,000 0,10402548 0,13927952 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,10402548 0,13920206 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,10402548 0,13912468 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,10402548 0,13904739 ! startle response GO:0001964 28 16 0,000 0,10402548 0,13897018 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,10402548 0,13889306 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,10402548 0,13881603 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,10402548 0,13873908 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,10402548 0,13866222 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,10402548 0,13858544 ! protein polyubiquitination GO:0000209 34 16 0,000 0,10402548 0,13850874 ! glutamate metabolic process GO:0006536 22 16 0,000 0,10402548 0,13843213 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,10402548 0,13835561 ! response to osmotic stress GO:0006970 25 16 0,000 0,10402548 0,13827917 ! lysosomal transport GO:0007041 26 16 0,000 0,10402548 0,13820282 ! fructose metabolic process GO:0006000 25 16 0,000 0,10402548 0,13812654 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10402548 0,13805036 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10402548 0,13797426 ! intermediate filament-based process GO:0045103 32 16 0,000 0,10402548 0,13789824 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,10402548 0,1378223 ! negative regulation of immune response GO:0050777 35 16 0,000 0,10402548 0,13774645 ! axon cargo transport GO:0008088 43 16 0,000 0,10402548 0,13767068 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,10402548 0,137595 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,10402548 0,1375194 ! DNA replication initiation GO:0006270 27 16 0,000 0,10402548 0,13744388 ! neuron recognition GO:0008038 35 16 0,000 0,10402548 0,13736844 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,10402548 0,13729309 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,10402548 0,13721782 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,10402548 0,13714263 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,10402548 0,13706752 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,10402548 0,1369925 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10402548 0,13691756 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,10402548 0,1368427 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,10402548 0,13676792 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,10415125 0,1368585 ! protein import into nucleus GO:0006606 158 80 1,000 0,10415125 0,1367838 ! T cell activation GO:0042110 168 81 1,000 0,10632694 0,13956498 ! nuclear import GO:0051170 161 81 1,000 0,10632694 0,13948888 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,10851485 0,1422816 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,10851485 0,14220411 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,11015719 0,14427774 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,11015719 0,14419924 ! metencephalon development GO:0022037 30 17 0,000 0,11015719 0,14412083 ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,11015719 0,1440425 ! endothelial cell migration GO:0043542 28 17 0,000 0,11015719 0,14396426 ! inositol metabolic process GO:0006020 28 17 0,000 0,11015719 0,14388611 ! gene silencing by RNA GO:0031047 36 17 0,000 0,11015719 0,14380803 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,11015719 0,14373005 ! glial cell development GO:0021782 27 17 0,000 0,11015719 0,14365214 ! adult walking behavior GO:0007628 33 17 0,000 0,11015719 0,14357433 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,11015719 0,14349659 ! heart looping GO:0001947 30 17 0,000 0,11015719 0,14341894 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,11015719 0,14334138 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,11015719 0,14326389 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,11015719 0,1431865 ! glycine metabolic process GO:0006544 28 17 0,000 0,11015719 0,14310918 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,11015719 0,14303195 ! NAD metabolic process GO:0019674 29 17 0,000 0,11015719 0,1429548 ! membrane budding GO:0006900 37 17 0,000 0,11015719 0,14287774 ! DNA integration GO:0015074 29 17 0,000 0,11015719 0,14280076 ! regulation of protein binding GO:0043393 33 17 0,000 0,11015719 0,14272386 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,11015719 0,14264704 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,11015719 0,14257031 ! genitalia development GO:0048806 30 17 0,000 0,11015719 0,14249366 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,11015719 0,14241709 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,11015719 0,1423406 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,11015719 0,1422642 ! steroid catabolic process GO:0006706 31 17 0,000 0,11015719 0,14218788 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,11015719 0,14211164 ! gas transport GO:0015669 25 17 0,000 0,11015719 0,14203548 ! organic cation transport GO:0015695 31 17 0,000 0,11015719 0,1419594 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,11015719 0,14188341 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,11015719 0,14180749 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,11015719 0,14173166 ! regulation of lyase activity GO:0051339 160 83 1,000 0,11071474 0,14237288 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,11292633 0,14513929 ! hemostasis GO:0007599 158 84 1,000 0,11292633 0,1450618 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,11514936 0,1478385 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11624715 0,14916834 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11624715 0,14908882 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,11624715 0,1490094 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11624715 0,14893005 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11624715 0,14885079 ! memory GO:0007613 31 18 0,000 0,11624715 0,14877161 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11624715 0,14869252 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11624715 0,14861351 ! patterning of blood vessels GO:0001569 39 18 0,000 0,11624715 0,14853459 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11624715 0,14845575 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,11624715 0,14837699 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,11624715 0,14829832 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11624715 0,14821973 ! response to fungus GO:0009620 21 18 0,000 0,11624715 0,14814123 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11624715 0,1480628 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11624715 0,14798446 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11624715 0,14790621 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,11624715 0,14782803 ! vitamin transport GO:0051180 27 18 0,000 0,11624715 0,14774994 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11624715 0,14767193 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11624715 0,147594 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11624715 0,14751616 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,11624715 0,14743839 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,11624715 0,14736071 ! nerve development GO:0021675 28 18 0,000 0,11624715 0,14728311 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11624715 0,1472056 ! tube morphogenesis GO:0035239 176 86 1,000 0,11738357 0,14856648 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,11962872 0,15132844 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,11962872 0,15124892 ! protein secretion GO:0009306 39 19 0,000 0,12229562 0,15453953 ! negative regulation of defense response GO:0031348 25 19 0,000 0,12229562 0,15445841 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,12229562 0,15437737 ! skin development GO:0043588 36 19 0,000 0,12229562 0,15429642 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,12229562 0,15421555 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,12229562 0,15413477 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,12229562 0,15405407 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,12229562 0,15397345 ! bile acid metabolic process GO:0008206 29 19 0,000 0,12229562 0,15389292 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,12229562 0,15381248 ! cerebral cortex development GO:0021987 36 19 0,000 0,12229562 0,15373212 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,12229562 0,15365184 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,12229562 0,15357164 ! peptide cross-linking GO:0018149 37 19 0,000 0,12229562 0,15349153 ! protein export from nucleus GO:0006611 36 19 0,000 0,12229562 0,15341151 ! heart process GO:0003015 30 19 0,000 0,12229562 0,15333156 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,12229562 0,1532517 ! visual learning GO:0008542 36 19 0,000 0,12229562 0,15317193 ! G1 phase GO:0051318 40 19 0,000 0,12229562 0,15309223 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,12229562 0,15301262 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,12229562 0,15293309 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,12229562 0,15285365 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,12229562 0,15277428 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,12229562 0,152695 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,12229562 0,1526158 ! cilium assembly GO:0042384 37 19 0,000 0,12229562 0,15253669 ! cellular defense response GO:0006968 114 89 1,000 0,12415079 0,15477036 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,12642722 0,15752662 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,1283029 0,15978094 ! positive regulation of ossification GO:0045778 47 20 0,000 0,1283029 0,15969828 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,1283029 0,15961571 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,1283029 0,15953322 ! cAMP metabolic process GO:0046058 36 20 0,000 0,1283029 0,15945082 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,1283029 0,1593685 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,1283029 0,15928627 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,1283029 0,15920412 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,1283029 0,15912205 ! retinoid metabolic process GO:0001523 32 20 0,000 0,1283029 0,15904007 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,1283029 0,15895818 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,1283029 0,15887637 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,1283029 0,15879464 ! body fluid secretion GO:0007589 31 20 0,000 0,1283029 0,158713 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,1283029 0,15863144 ! stem cell differentiation GO:0048863 53 20 0,000 0,1283029 0,15854997 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,1283029 0,15846857 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,1283029 0,15838727 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,1283029 0,15830604 ! sensory perception of pain GO:0019233 30 20 0,000 0,1283029 0,1582249 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,1283029 0,15814384 ! diencephalon development GO:0021536 34 20 0,000 0,1283029 0,15806287 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,1283029 0,15798198 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,1283029 0,15790117 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,1283029 0,15782044 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,1283029 0,1577398 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,1283029 0,15765924 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,1283029 0,15757876 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,1283029 0,15749836 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,1283029 0,15741804 ! actin filament-based movement GO:0030048 43 20 0,000 0,1283029 0,15733781 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,1283029 0,15725766 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,1283029 0,15717759 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,1283029 0,1570976 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,13331519 0,16315175 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,13331519 0,1630688 ! regulation of membrane potential GO:0042391 164 93 1,000 0,13331519 0,16298594 ! regulation of cell killing GO:0031341 42 21 0,000 0,13426926 0,164069 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,13426926 0,16398571 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,13426926 0,16390251 ! glycerol metabolic process GO:0006071 34 21 0,000 0,13426926 0,1638194 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,13426926 0,16373637 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,13426926 0,16365342 ! axis specification GO:0009798 38 21 0,000 0,13426926 0,16357056 ! ovarian follicle development GO:0001541 35 21 0,000 0,13426926 0,16348778 ! smooth muscle contraction GO:0006939 46 21 0,000 0,13426926 0,16340508 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,13426926 0,16332247 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,13426926 0,16323995 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,13426926 0,1631575 ! cytolysis GO:0019835 24 21 0,000 0,13426926 0,16307514 ! vasodilation GO:0042311 39 21 0,000 0,13426926 0,16299286 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,13426926 0,16291067 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,13426926 0,16282855 ! collagen fibril organization GO:0030199 59 21 0,000 0,13426926 0,16274652 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,13426926 0,16266458 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,13426926 0,16258271 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,13426926 0,16250093 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,13426926 0,16241923 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,13426926 0,16233761 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,13426926 0,16225608 ! sperm-egg recognition GO:0035036 21 21 0,000 0,13426926 0,16217462 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,13562994 0,16373589 ! female pregnancy GO:0007565 164 94 1,000 0,13562994 0,16365378 ! transcription initiation GO:0006352 153 94 1,000 0,13562994 0,16357175 ! forebrain development GO:0030900 188 95 1,000 0,13795368 0,16629086 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,14019499 0,16890793 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,14019499 0,16882339 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,14019499 0,16873894 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,14019499 0,16865457 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,14019499 0,16857028 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,14019499 0,16848608 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,14019499 0,16840197 ! regeneration GO:0031099 41 22 0,000 0,14019499 0,16831793 ! keratinization GO:0031424 28 22 0,000 0,14019499 0,16823398 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,14019499 0,16815012 ! sensory perception of taste GO:0050909 28 22 0,000 0,14019499 0,16806634 ! vacuolar transport GO:0007034 36 22 0,000 0,14019499 0,16798264 ! lysosome organization GO:0007040 41 22 0,000 0,14019499 0,16789902 ! central nervous system neuron development GO:0021954 46 22 0,000 0,14019499 0,16781549 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,14019499 0,16773204 ! fucose metabolic process GO:0006004 39 22 0,000 0,14019499 0,16764868 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,14019499 0,16756539 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,14019499 0,16748219 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,14019499 0,16739908 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,14019499 0,16731604 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,14019499 0,16723309 ! sarcomere organization GO:0045214 30 22 0,000 0,14019499 0,16715022 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,14019499 0,16706743 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,14019499 0,16698472 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,14019499 0,1669021 ! detection of stimulus GO:0051606 151 96 1,000 0,14028619 0,16692808 ! protein ubiquitination GO:0016567 217 97 1,000 0,14262723 0,16962982 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,14608034 0,17365084 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,14608034 0,17356509 ! viral genome replication GO:0019079 41 23 0,000 0,14608034 0,17347942 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,14608034 0,17339384 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,14608034 0,17330834 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,14608034 0,17322292 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,14608034 0,17313759 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,14608034 0,17305234 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,14608034 0,17296718 ! visual behavior GO:0007632 42 23 0,000 0,14608034 0,1728821 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,14608034 0,1727971 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,14608034 0,17271219 ! response to ethanol GO:0045471 46 23 0,000 0,14608034 0,17262736 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,14608034 0,17254262 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,14608034 0,17245795 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,14608034 0,17237337 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,14608034 0,17228888 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,14608034 0,17220446 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,14608034 0,17212013 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,14608034 0,17203588 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,14608034 0,17195172 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,14608034 0,17186763 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,14608034 0,17178363 ! fatty acid transport GO:0015908 44 23 0,000 0,14608034 0,17169971 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,14608034 0,17161587 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,14608034 0,17153212 ! cell-cell recognition GO:0009988 25 23 0,000 0,14608034 0,17144844 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,14608034 0,17136485 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,14608034 0,17128134 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,14608034 0,17119791 GO:0006099|tricarboxylic acid cycle, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,14733403 0,1725831 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,15192561 0,17787495 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,15192561 0,17778843 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,15192561 0,177702 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,15192561 0,17761566 ! vesicle docking GO:0048278 47 24 0,000 0,15192561 0,17752939 ! vacuole organization GO:0007033 43 24 0,000 0,15192561 0,17744321 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,15192561 0,17735712 ! digestive system process GO:0022600 39 24 0,000 0,15192561 0,17727111 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,15192561 0,17718518 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,15192561 0,17709933 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,15192561 0,17701357 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,15192561 0,17692789 ! membrane depolarization GO:0051899 39 24 0,000 0,15192561 0,17684229 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,15192561 0,17675678 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,15192561 0,17667135 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,15192561 0,176586 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,15192561 0,17650073 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,15192561 0,17641555 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,15192561 0,17633045 ! regulation of amine transport GO:0051952 40 24 0,000 0,15192561 0,17624543 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,15773106 0,18289201 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,15773106 0,18280391 ! phototransduction GO:0007602 33 25 0,000 0,15773106 0,1827159 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,15773106 0,18262797 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,15773106 0,18254013 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,15773106 0,18245237 ! osteoblast differentiation GO:0001649 60 25 0,000 0,15773106 0,18236469 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,15773106 0,1822771 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,15773106 0,18218959 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,15773106 0,18210217 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,15773106 0,18201483 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,15773106 0,18192758 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,15773106 0,18184041 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,15773106 0,18175332 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,15773106 0,18166631 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,15773106 0,18157939 ! telomere organization GO:0032200 43 25 0,000 0,15773106 0,18149255 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,15773106 0,1814058 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,15773106 0,18131912 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,16349696 0,18785753 ! embryonic pattern specification GO:0009880 44 26 0,000 0,16349696 0,18776786 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,16349696 0,18767828 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,16349696 0,18758878 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,16349696 0,18749937 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,16349696 0,18741004 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,16349696 0,1873208 ! tube lumen formation GO:0035148 50 26 0,000 0,16349696 0,18723164 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,16349696 0,18714257 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,16349696 0,18705358 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,16349696 0,18696468 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,16349696 0,18687586 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,16349696 0,18678712 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,16349696 0,18669847 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,16349696 0,1866099 ! leukocyte proliferation GO:0070661 52 26 0,000 0,16349696 0,18652142 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,16349696 0,18643302 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,16349696 0,18634471 ! iron ion transport GO:0006826 59 27 0,000 0,16922357 0,19278026 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,16922357 0,19268903 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,16922357 0,19259788 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,16922357 0,19250682 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,16922357 0,19241584 ! autophagy GO:0006914 41 27 0,000 0,16922357 0,19232495 ! primary neural tube formation GO:0014020 51 27 0,000 0,16922357 0,19223414 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,16922357 0,19214342 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,16922357 0,19205279 ! glutathione metabolic process GO:0006749 39 27 0,000 0,16922357 0,19196224 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,16922357 0,19187178 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,16922357 0,1917814 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,17491117 0,19813385 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,17491117 0,19804061 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,17491117 0,19794745 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,17491117 0,19785439 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,17491117 0,19776141 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,17491117 0,19766852 ! synaptogenesis GO:0007416 42 28 0,000 0,17491117 0,19757572 ! lipid oxidation GO:0034440 43 28 0,000 0,17491117 0,19748301 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,17491117 0,19739038 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,17491117 0,19729784 ! translational initiation GO:0006413 65 29 0,000 0,18056003 0,20357424 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,18056003 0,20347889 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,18056003 0,20338363 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,18056003 0,20328845 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,18056003 0,20319337 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,18056003 0,20309837 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,18056003 0,20300347 ! detection of light stimulus GO:0009583 38 29 0,000 0,18056003 0,20290865 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,18056003 0,20281392 ! regulation of coagulation GO:0050818 46 29 0,000 0,18056003 0,20271928 ! zinc ion transport GO:0006829 45 30 0,000 0,18617039 0,20892069 ! membrane docking GO:0022406 61 30 0,000 0,18617039 0,20882329 ! regulation of innate immune response GO:0045088 51 30 0,000 0,18617039 0,20872598 ! myofibril assembly GO:0030239 47 30 0,000 0,18617039 0,20862877 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,18617039 0,20853164 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,18617039 0,2084346 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,18617039 0,20833766 ! phospholipid transport GO:0015914 51 30 0,000 0,18617039 0,2082408 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,18617039 0,20814403 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,18617039 0,20804736 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,18617039 0,20795077 ! eye morphogenesis GO:0048592 60 30 0,000 0,18617039 0,20785427 ! response to heat GO:0009408 50 30 0,000 0,18617039 0,20775787 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,19174253 0,21387692 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,19174253 0,21377781 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,19174253 0,2136788 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,19174253 0,21357987 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,19174253 0,21348104 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,19174253 0,2133823 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,19174253 0,21328364 ! ovulation cycle process GO:0022602 49 31 0,000 0,19174253 0,21318508 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,19174253 0,21308662 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,19174253 0,21298824 ! mesoderm formation GO:0001707 69 31 0,000 0,19174253 0,21288995 ! natural killer cell activation GO:0030101 45 31 0,000 0,19174253 0,21279175 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,19174253 0,21269365 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,19174253 0,21259563 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,19174253 0,21249771 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,1972767 0,21853027 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1972767 0,2184297 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1972767 0,21832923 ! cholesterol transport GO:0030301 56 32 0,000 0,1972767 0,21822884 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1972767 0,21812855 ! spliceosome assembly GO:0000245 67 32 0,000 0,1972767 0,21802836 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1972767 0,21792825 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1972767 0,21782824 ! muscle cell development GO:0055001 49 32 0,000 0,1972767 0,21772832 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1972767 0,21762849 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1972767 0,21752875 ! ovulation cycle GO:0042698 51 32 0,000 0,1972767 0,2174291 ! BMP signaling pathway GO:0030509 64 32 0,000 0,1972767 0,21732955 ! hindbrain development GO:0030902 61 32 0,000 0,1972767 0,21723008 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1972767 0,21713071 ! gene silencing GO:0016458 65 32 0,000 0,1972767 0,21703143 ! post-embryonic development GO:0009791 69 33 0,000 0,20277316 0,22297633 ! protein targeting to membrane GO:0006612 68 33 0,000 0,20277316 0,22287447 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,20277316 0,2227727 ! ceramide metabolic process GO:0006672 64 33 0,000 0,20277316 0,22267103 ! formation of primary germ layer GO:0001704 72 33 0,000 0,20277316 0,22256944 ! sterol transport GO:0015918 57 33 0,000 0,20277316 0,22246795 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,20277316 0,22236655 ! adult locomotory behavior GO:0008344 59 33 0,000 0,20277316 0,22226525 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,20277316 0,22216403 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,20823216 0,22804123 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,20823216 0,22793748 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,20823216 0,22783383 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,20823216 0,22773027 ! spermatid development GO:0007286 63 34 0,000 0,20823216 0,2276268 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,20823216 0,22752343 ! regulation of muscle development GO:0048634 70 35 0,000 0,21365397 0,23334156 ! odontogenesis GO:0042476 66 35 0,000 0,21365397 0,23323569 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,21365397 0,23312991 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,21365397 0,23302423 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,21365397 0,23291865 ! neural tube formation GO:0001841 67 35 0,000 0,21365397 0,23281316 ! vesicle localization GO:0051648 64 35 0,000 0,21365397 0,23270776 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,21903883 0,23846489 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,21903883 0,23835704 ! positive regulation of cell development GO:0010720 80 36 0,000 0,21903883 0,23824928 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,21903883 0,23814163 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,21903883 0,23803406 ! aerobic respiration GO:0009060 55 36 0,000 0,21903883 0,2379266 ! embryonic organ development GO:0048568 57 36 0,000 0,21903883 0,23781923 ! RNA export from nucleus GO:0006405 56 37 0,000 0,22438699 0,24351605 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,22438699 0,24340626 ! actomyosin structure organization GO:0031032 62 37 0,000 0,22438699 0,24329657 ! organic anion transport GO:0015711 68 37 0,000 0,22438699 0,24318698 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,22438699 0,24307748 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,22438699 0,24296809 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,22438699 0,24285879 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,22438699 0,24274959 ! spermatid differentiation GO:0048515 66 37 0,000 0,22438699 0,24264049 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,2296987 0,24827272 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,2296987 0,24816123 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,2296987 0,24804985 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,2296987 0,24793857 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,2296987 0,24782738 ! lipid homeostasis GO:0055088 67 38 0,000 0,2296987 0,2477163 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,2296987 0,24760532 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,2296987 0,24749443 ! mRNA catabolic process GO:0006402 71 39 0,000 0,23497421 0,25306533 ! organic ether metabolic process GO:0018904 55 39 0,000 0,23497421 0,2529521 ! ion transmembrane transport GO:0034220 66 39 0,000 0,23497421 0,25283897 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,23497421 0,25272595 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,23497421 0,25261302 ! RNA modification GO:0009451 57 39 0,000 0,23497421 0,2525002 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,24021376 0,25801532 ! feeding behavior GO:0007631 59 40 0,000 0,24021376 0,25790018 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,24021376 0,25778515 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,24541761 0,26325223 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,24541761 0,26313492 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,24541761 0,26301771 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,24541761 0,2629006 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,24541761 0,2627836 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,24541761 0,26266671 ! polyol metabolic process GO:0019751 66 41 0,000 0,24541761 0,26254991 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,24541761 0,26243323 ! regulation of tube size GO:0035150 71 42 0,000 0,25058598 0,2678409 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,25058598 0,26772196 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,25058598 0,26760313 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,25058598 0,26748441 ! neuron migration GO:0001764 79 42 0,000 0,25058598 0,26736579 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,25571912 0,27272172 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,25571912 0,27260089 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,25571912 0,27248016 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,25571912 0,27235954 ! neural tube development GO:0021915 77 43 0,000 0,25571912 0,27223903 ! striated muscle contraction GO:0006941 77 43 0,000 0,25571912 0,27211862 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,25571912 0,27199832 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,26081727 0,27729844 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,26081727 0,27717595 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,26081727 0,27705358 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,26588067 0,28230755 ! glycolysis GO:0006096 65 45 0,000 0,26588067 0,28218302 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,26588067 0,2820586 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,26588067 0,28193429 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,26588067 0,28181009 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,26588067 0,281686 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,26588067 0,28156202 ! cell growth GO:0016049 84 45 0,000 0,26588067 0,28143814 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,27090956 0,28663518 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,27090956 0,28650919 ! response to calcium ion GO:0051592 81 47 0,000 0,27590416 0,29166318 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,27590416 0,29153509 ! JNK cascade GO:0007254 91 47 0,000 0,27590416 0,29140711 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,27590416 0,29127925 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,28086471 0,29638618 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,28086471 0,29625624 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,28086471 0,29612642 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,28579144 0,30118888 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,28579144 0,30105701 ! regulation of ion transport GO:0043269 77 49 0,000 0,28579144 0,30092525 ! peptide metabolic process GO:0006518 76 49 0,000 0,28579144 0,30079361 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,28579144 0,30066209 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,28579144 0,30053068 ! inner ear development GO:0048839 79 50 0,000 0,29068458 0,30554264 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,29554436 0,31051517 ! excretion GO:0007588 83 51 0,000 0,29554436 0,31037963 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,29554436 0,31024421 ! chromatin remodeling GO:0006338 109 51 0,000 0,29554436 0,31010891 ! vesicle organization GO:0016050 107 51 0,000 0,29554436 0,30997373 ! positive regulation of growth GO:0045927 90 52 0,000 0,300371 0,31489875 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,300371 0,3147616 ! amino acid activation GO:0043038 92 52 0,000 0,300371 0,31462457 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,30516474 0,31950668 ! RNA catabolic process GO:0006401 93 53 0,000 0,30516474 0,31936771 ! regulation of translational initiation GO:0006446 82 53 0,000 0,30516474 0,31922885 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,30516474 0,31909011 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,30516474 0,3189515 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,30516474 0,31881301 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,30516474 0,31867463 ! cell recognition GO:0008037 85 54 0,000 0,30992578 0,32350604 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,30992578 0,32336575 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,30992578 0,32322559 ! chloride transport GO:0006821 90 55 0,000 0,31465436 0,3280149 ! glucose catabolic process GO:0006007 82 55 0,000 0,31465436 0,32787284 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,31465436 0,32773091 ! gastrulation GO:0007369 112 55 0,000 0,31465436 0,32758909 ! heart morphogenesis GO:0003007 97 55 0,000 0,31465436 0,3274474 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,31465436 0,32730583 ! RNA elongation GO:0006354 79 55 0,000 0,31465436 0,32716439 ! nuclear export GO:0051168 97 55 0,000 0,31465436 0,32702306 ! regulation of actin filament length GO:0030832 105 56 0,000 0,31935069 0,3317607 ! sensory perception of smell GO:0007608 80 56 0,000 0,31935069 0,33161751 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,31935069 0,33147445 ! proton transport GO:0015992 94 56 0,000 0,31935069 0,33133151 ! hydrogen transport GO:0006818 97 58 0,000 0,3286475 0,34083012 ! regulation of endocytosis GO:0030100 91 58 0,000 0,3286475 0,34068328 ! adult behavior GO:0030534 99 58 0,000 0,3286475 0,34053656 ! regulation of cellular component size GO:0032535 109 59 0,000 0,33324841 0,34515526 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,33324841 0,34500674 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,33324841 0,34485835 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,33781793 0,34943678 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,33781793 0,34928661 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,34235629 0,35382699 ! tRNA processing GO:0008033 89 61 0,000 0,34235629 0,35367507 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,34235629 0,35352328 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,3468637 0,35802405 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,35134036 0,36248924 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,35134036 0,36233387 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,35578649 0,36676191 ! cell redox homeostasis GO:0045454 102 64 0,000 0,35578649 0,36660484 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,35578649 0,3664479 ! single fertilization GO:0007338 75 64 0,000 0,35578649 0,3662911 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,36020229 0,37067866 ! extracellular matrix organization GO:0030198 133 66 0,000 0,36458796 0,37503148 ! secondary metabolic process GO:0019748 116 66 0,000 0,36458796 0,37487121 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,36894372 0,37918778 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,36894372 0,37902587 ! activation of MAPK activity GO:0000187 115 67 0,000 0,36894372 0,3788641 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,36894372 0,37870247 ! hexose catabolic process GO:0019320 104 67 0,000 0,36894372 0,37854098 ! activation of immune response GO:0002253 105 67 0,000 0,36894372 0,37837962 ! amino acid transport GO:0006865 125 68 0,000 0,37326976 0,3826532 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,37326976 0,38249023 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,37326976 0,3823274 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,37326976 0,3821647 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,37756629 0,38639919 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,37756629 0,38623491 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,37756629 0,38607076 ! antigen processing and presentation GO:0019882 104 69 0,000 0,37756629 0,38590676 ! amine catabolic process GO:0009310 117 71 0,000 0,38607161 0,3944324 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,3902808 0,3985635 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,3902808 0,3983944 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,39446127 0,40249102 ! fertilization GO:0009566 90 73 0,000 0,39446127 0,4023204 ! transition metal ion transport GO:0000041 126 74 0,000 0,39861321 0,40638279 ! neurotransmitter transport GO:0006836 123 74 0,000 0,39861321 0,40621067 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,39861321 0,40603869 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,40273682 0,41006551 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,40273682 0,40989205 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,4068323 0,4138852 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,4068323 0,41371027 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,4068323 0,41353549 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,41089982 0,41749366 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,41089982 0,41731742 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,41089982 0,41714134 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,41493959 0,42106481 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,41895179 0,424957 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,41895179 0,42477792 ! response to metal ion GO:0010038 140 80 0,000 0,42293661 0,42863752 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,42293661 0,42845704 ! inorganic anion transport GO:0015698 138 80 0,000 0,42293661 0,42827672 ! digestion GO:0007586 112 81 0,000 0,42689423 0,43210245 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,42689423 0,43192074 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,43082484 0,4357144 ! regulation of ligase activity GO:0051340 142 84 0,000 0,43860576 0,44339725 ! response to unfolded protein GO:0006986 131 85 0,000 0,44245643 0,44710213 ! nucleosome assembly GO:0006334 122 85 0,000 0,44245643 0,44691443 ! response to inorganic substance GO:0010035 153 86 0,000 0,44628081 0,45058818 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,44628081 0,45039918 ! chromatin assembly GO:0031497 124 86 0,000 0,44628081 0,45021033 ! alcohol catabolic process GO:0046164 130 86 0,000 0,44628081 0,45002164 ! amine transport GO:0015837 155 86 0,000 0,44628081 0,44983311 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,45007909 0,45347165 ! cellular respiration GO:0045333 135 88 0,000 0,45385145 0,45708103 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,45385145 0,45688978 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,46131906 0,46421316 ! sterol metabolic process GO:0016125 152 91 0,000 0,46501468 0,46773634 ! response to protein stimulus GO:0051789 149 91 0,000 0,46501468 0,46754088 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,46501468 0,46734558 ! nucleosome organization GO:0034728 138 92 0,000 0,46868507 0,47083769 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,46868507 0,47064118 ! vitamin metabolic process GO:0006766 139 92 0,000 0,46868507 0,47044483 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,47233039 0,47390614 GO:0010498|proteasomal protein catabolic process, ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,4831177 0,48452738 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,4831177 0,4843255 ! positive regulation of immune response GO:0050778 156 96 0,000 0,4831177 0,48412378 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,48666448 0,48747491 ! hormone metabolic process GO:0042445 157 97 0,000 0,48666448 0,48727205 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,49018703 0,49059484 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,49018703 0,49039085 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,49368553 0,49368553