pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6935-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 3,092E-11 7,554E-08 ! negative regulation of phosphorylation GO:0042326 52 24 5,000 8,397E-09 1,026E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 5,000 1,421E-08 1,157E-05 GO:0045936|negative regulation of phosphate metabolic process, ! induction of apoptosis by intracellular signals GO:0008629 95 45 6,000 1,596E-08 9,748E-06 ! filopodium assembly GO:0046847 42 17 4,000 6,308E-08 3,082E-05 ! microspike assembly GO:0030035 46 18 4,000 8,689E-08 3,538E-05 ! induction of positive chemotaxis GO:0050930 17 9 3,000 2,098E-07 7,322E-05 ! positive regulation of locomotion GO:0040017 44 22 4,000 2,615E-07 7,985E-05 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 4,000 3,323E-07 9,021E-05 ! regulation of behavior GO:0050795 48 25 4,000 5,192E-07 1,269E-04 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 8,118E-07 1,803E-04 GO:0050927|positive regulation of positive chemotaxis, ! response to UV GO:0009411 120 55 5,000 1,53E-06 3,114E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 1,625E-06 3,054E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 5,272E-06 9,2E-04 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 2,000 5,272E-06 8,587E-04 ! nuclear migration GO:0007097 13 6 2,000 5,272E-06 8,05E-04 ! L-serine biosynthetic process GO:0006564 7 6 2,000 5,272E-06 7,577E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 5,272E-06 7,156E-04 GO:0031272|regulation of pseudopodium assembly, ! cell projection assembly GO:0030031 138 68 5,000 5,385E-06 6,924E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 5,000 5,866E-06 7,165E-04 ! developmental maturation GO:0021700 128 69 5,000 5,866E-06 6,824E-04 ! negative regulation of kinase activity GO:0033673 145 70 5,000 6,381E-06 7,086E-04 ! establishment or maintenance of cell polarity GO:0007163 96 41 4,000 6,732E-06 7,15E-04 ! regulation of intracellular protein transport GO:0033157 86 42 4,000 7,601E-06 7,737E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 3,000 7,628E-06 7,455E-04 ! pancreas development GO:0031016 40 20 3,000 7,628E-06 7,168E-04 ! negative regulation of transferase activity GO:0051348 155 74 5,000 8,824E-06 7,984E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 9,183E-06 8,012E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 9,183E-06 7,736E-04 ! positive regulation of inflammatory response GO:0050729 41 21 3,000 9,376E-06 7,635E-04 ! positive regulation of response to external stimulus GO:0032103 88 44 4,000 9,602E-06 7,567E-04 ! regulation of epithelial cell proliferation GO:0050678 122 45 4,000 1,075E-05 8,204E-04 ! positive regulation of intracellular transport GO:0032388 42 22 3,000 1,14E-05 8,44E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 1,199E-05 8,617E-04 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 4,000 1,199E-05 8,371E-04 ! positive regulation of protein transport GO:0051222 80 46 4,000 1,199E-05 8,139E-04 ! response to molecule of bacterial origin GO:0002237 40 23 3,000 1,373E-05 9,066E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,462E-05 9,4E-04 ! ER overload response GO:0006983 13 8 2,000 1,462E-05 9,159E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 1,462E-05 8,93E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,462E-05 8,713E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 1,462E-05 8,505E-04 ! regulation of inflammatory response GO:0050727 84 48 4,000 1,482E-05 8,423E-04 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 1,639E-05 9,102E-04 ! vasculogenesis GO:0001570 49 25 3,000 1,942E-05 1,054E-03 ! negative regulation of transport GO:0051051 164 85 5,000 1,964E-05 1,043E-03 ! macrophage differentiation GO:0030225 15 9 2,000 2,183E-05 1,135E-03 ! regulation of protein transport GO:0051223 165 87 5,000 2,243E-05 1,142E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of angiogenesis GO:0045765 125 54 4,000 2,653E-05 1,323E-03 ! regulation of cell shape GO:0008360 142 54 4,000 2,653E-05 1,296E-03 ! cell maturation GO:0048469 107 55 4,000 2,903E-05 1,391E-03 ! negative regulation of protein modification process GO:0031400 66 28 3,000 3,095E-05 1,454E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 2,000 3,103E-05 1,43E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 3,103E-05 1,404E-03 ! DNA ligation GO:0006266 18 10 2,000 3,103E-05 1,378E-03 ! protein sumoylation GO:0016925 17 10 2,000 3,103E-05 1,354E-03 ! regulation of intracellular transport GO:0032386 108 57 4,000 3,458E-05 1,482E-03 ! regulation of protein localization GO:0032880 188 97 5,000 4,159E-05 1,752E-03 ! L-serine metabolic process GO:0006563 21 11 2,000 4,247E-05 1,758E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 4,247E-05 1,729E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 4,247E-05 1,701E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 2,000 4,247E-05 1,673E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 4,247E-05 1,647E-03 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 22 11 2,000 4,247E-05 1,621E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 5,635E-05 2,118E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 2,000 5,635E-05 2,086E-03 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 2,000 5,635E-05 2,055E-03 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of hormone metabolic process GO:0032350 28 12 2,000 5,635E-05 2,025E-03 ! regulation of leukocyte migration GO:0002685 29 12 2,000 5,635E-05 1,995E-03 ! leukocyte chemotaxis GO:0030595 55 33 3,000 6,031E-05 2,105E-03 GO:0060326|cell chemotaxis, ! response to X-ray GO:0010165 28 13 2,000 7,291E-05 2,509E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 8,714E-05 2,957E-03 ! response to gamma radiation GO:0010332 30 14 2,000 9,235E-05 3,091E-03 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 9,235E-05 3,049E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 9,235E-05 3,008E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 1,149E-04 3,693E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 1,149E-04 3,645E-03 ! regulation of caspase activity GO:0043281 136 74 4,000 1,217E-04 3,811E-03 ! positive regulation of protein import into nucleus GO:0042307 34 16 2,000 1,407E-04 4,352E-03 ! regulation of hormone secretion GO:0046883 69 41 3,000 1,433E-04 4,377E-03 ! mesenchymal cell development GO:0014031 94 41 3,000 1,433E-04 4,323E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of endopeptidase activity GO:0052548 141 77 4,000 1,469E-04 4,377E-03 ! myoblast differentiation GO:0045445 50 17 2,000 1,701E-04 5,006E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,701E-04 4,946E-03 ! activation of protein kinase activity GO:0032147 170 80 4,000 1,76E-04 5,057E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 1,866E-04 5,299E-03 ! regulation of peptidase activity GO:0052547 150 82 4,000 1,976E-04 5,549E-03 ! response to retinoic acid GO:0032526 31 18 2,000 2,031E-04 5,638E-03 ! negative regulation of protein catabolic process GO:0042177 42 18 2,000 2,031E-04 5,575E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 2,092E-04 5,679E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to nutrient GO:0007584 135 84 4,000 2,213E-04 5,94E-03 ! leukocyte migration GO:0050900 75 46 3,000 2,252E-04 5,98E-03 ! pigmentation GO:0043473 103 46 3,000 2,252E-04 5,916E-03 ! neuron maturation GO:0042551 46 19 2,000 2,4E-04 6,238E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 2,4E-04 6,173E-03 ! response to vitamin A GO:0033189 32 19 2,000 2,4E-04 6,108E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 2,658E-04 6,695E-03 ! positive regulation of defense response GO:0031349 88 48 3,000 2,658E-04 6,626E-03 ! response to vitamin GO:0033273 36 20 2,000 2,81E-04 6,935E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 2,81E-04 6,866E-03 ! regulation of glucose import GO:0046324 30 20 2,000 2,81E-04 6,798E-03 GO:0010827|regulation of glucose transport, ! regulation of mast cell proliferation GO:0070666 89 49 3,000 2,88E-04 6,897E-03 ! regulation of cell morphogenesis GO:0022604 243 93 4,000 3,554E-04 8,429E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 3,76E-04 8,833E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 3,76E-04 8,749E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 3,76E-04 8,667E-03 ! cell aging GO:0007569 48 22 2,000 3,76E-04 8,586E-03 ! positive regulation of B cell activation GO:0050871 42 22 2,000 3,76E-04 8,506E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 3,9E-04 8,742E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of defense response GO:0031347 171 95 4,000 3,921E-04 8,708E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,116E-04 9,059E-03 ! regulation of collagen biosynthetic process GO:0032965 7 5 1,000 4,116E-04 8,978E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 4,116E-04 8,898E-03 ! Notch receptor processing GO:0007220 11 5 1,000 4,116E-04 8,82E-03 ! response to protozoan GO:0001562 13 5 1,000 4,116E-04 8,744E-03 ! anagen GO:0042640 7 5 1,000 4,116E-04 8,668E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 4,116E-04 8,594E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 4,116E-04 8,521E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 4,116E-04 8,45E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 4,116E-04 8,379E-03 ! microvillus organization GO:0032528 8 5 1,000 4,116E-04 8,31E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,116E-04 8,242E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 4,116E-04 8,175E-03 ! depyrimidination GO:0045008 10 5 1,000 4,116E-04 8,109E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 4,116E-04 8,044E-03 ! decidualization GO:0046697 11 5 1,000 4,116E-04 7,98E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 4,116E-04 7,917E-03 ! enteric nervous system development GO:0048484 8 5 1,000 4,116E-04 7,856E-03 ! circadian behavior GO:0048512 15 5 1,000 4,116E-04 7,795E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 4,116E-04 7,735E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,116E-04 7,676E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,116E-04 7,617E-03 ! regulation of Rho GTPase activity GO:0032319 56 23 2,000 4,304E-04 7,906E-03 ! DNA modification GO:0006304 36 23 2,000 4,304E-04 7,847E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 4,524E-04 8,187E-03 ! skeletal muscle fiber development GO:0048741 130 56 3,000 4,819E-04 8,656E-03 ! regulation of protein catabolic process GO:0042176 126 56 3,000 4,819E-04 8,593E-03 ! sex determination GO:0007530 48 24 2,000 4,895E-04 8,666E-03 ! negative regulation of catabolic process GO:0009895 52 24 2,000 4,895E-04 8,604E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 4,963E-04 8,661E-03 GO:0060538|skeletal muscle organ development, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 5,156E-04 8,934E-03 ! muscle fiber development GO:0048747 131 57 3,000 5,156E-04 8,871E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 5,51E-04 9,414E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 5,536E-04 9,393E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 5,536E-04 9,328E-03 ! negative regulation of DNA replication GO:0008156 45 25 2,000 5,536E-04 9,264E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 5,536E-04 9,201E-03 ! establishment of organelle localization GO:0051656 122 59 3,000 5,881E-04 9,708E-03 ! erythrocyte maturation GO:0043249 8 6 1,000 6,147E-04 0,01007934 ! regulation of smooth muscle cell differentiation GO:0051150 12 6 1,000 6,147E-04 0,01001214 ! activation of MAPKKK activity GO:0000185 12 6 1,000 6,147E-04 9,946E-03 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 6,147E-04 9,88E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 1,000 6,147E-04 9,816E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 6,147E-04 9,752E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 6,147E-04 9,689E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 6,147E-04 9,627E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 10 6 1,000 6,147E-04 9,566E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 6,147E-04 9,505E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,147E-04 9,445E-03 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 1,000 6,147E-04 9,386E-03 ! hair follicle maturation GO:0048820 8 6 1,000 6,147E-04 9,328E-03 ! neutrophil homeostasis GO:0001780 11 6 1,000 6,147E-04 9,271E-03 ! salivary gland morphogenesis GO:0007435 14 6 1,000 6,147E-04 9,214E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 6,147E-04 9,157E-03 ! organ or tissue specific immune response GO:0002251 8 6 1,000 6,147E-04 9,102E-03 ! maternal placenta development GO:0001893 12 6 1,000 6,147E-04 9,047E-03 ! regulation of transcription factor import into nucleus GO:0042990 58 26 2,000 6,229E-04 9,112E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 6,229E-04 9,058E-03 ! negative regulation of cell development GO:0010721 83 26 2,000 6,229E-04 9,004E-03 GO:0050768|negative regulation of neurogenesis, ! blastocyst development GO:0001824 50 26 2,000 6,229E-04 8,951E-03 ! positive regulation of secretion GO:0051047 110 61 3,000 6,676E-04 9,538E-03 ! cytokine-mediated signaling pathway GO:0019221 112 61 3,000 6,676E-04 9,482E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 6,974E-04 9,848E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 6,974E-04 9,792E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 6,974E-04 9,736E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 7,774E-04 0,01079059 ! fat cell differentiation GO:0045444 57 28 2,000 7,774E-04 0,01072963 ! base-excision repair GO:0006284 41 28 2,000 7,774E-04 0,01066935 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 7,774E-04 0,01060974 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 8,006E-04 0,01086624 ! positive regulation of cell motion GO:0051272 157 65 3,000 8,488E-04 0,01145693 ! regulation of helicase activity GO:0051095 16 7 1,000 8,57E-04 0,01150317 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 8,57E-04 0,01144031 ! sleep GO:0030431 16 7 1,000 8,57E-04 0,01137813 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 8,57E-04 0,01131663 ! mRNA stabilization GO:0048255 18 7 1,000 8,57E-04 0,01125579 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 8,57E-04 0,0111956 ! rhythmic behavior GO:0007622 17 7 1,000 8,57E-04 0,01113605 ! neuron remodeling GO:0016322 16 7 1,000 8,57E-04 0,01107712 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 8,57E-04 0,01101882 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 1,000 8,57E-04 0,01096113 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 8,57E-04 0,01090404 ! centrosome duplication GO:0051298 14 7 1,000 8,57E-04 0,01084755 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 8,57E-04 0,01079163 ! B cell lineage commitment GO:0002326 21 7 1,000 8,57E-04 0,01073629 ! T cell lineage commitment GO:0002360 16 7 1,000 8,57E-04 0,01068151 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 8,57E-04 0,01062729 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 1,000 8,57E-04 0,01057362 ! defense response to Gram-negative bacterium GO:0050829 10 7 1,000 8,57E-04 0,01052048 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 2,000 8,63E-04 0,01054103 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 8,63E-04 0,01048859 ! regulation of peptide secretion GO:0002791 52 29 2,000 8,63E-04 0,01043666 ! gonad development GO:0008406 115 66 3,000 8,991E-04 0,01081969 ! negative regulation of cell growth GO:0030308 142 67 3,000 9,513E-04 0,01139271 ! chromosome segregation GO:0007059 127 67 3,000 9,513E-04 0,01133714 ! myeloid cell differentiation GO:0030099 126 67 3,000 9,513E-04 0,0112821 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 9,543E-04 0,01126241 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 2,000 9,543E-04 0,01120826 ! regulation of B cell activation GO:0050864 55 30 2,000 9,543E-04 0,01115463 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 1,052E-03 0,01223257 ! negative regulation of cell size GO:0045792 144 69 3,000 1,062E-03 0,01229887 ! urogenital system development GO:0001655 149 69 3,000 1,062E-03 0,01224086 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,138E-03 0,01304943 ! male meiosis GO:0007140 9 8 1,000 1,138E-03 0,01298845 ! prostaglandin biosynthetic process GO:0001516 15 8 1,000 1,138E-03 0,01292804 GO:0046457|prostanoid biosynthetic process, ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,138E-03 0,01286819 ! negative regulation of muscle cell differentiation GO:0051148 17 8 1,000 1,138E-03 0,01280889 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,138E-03 0,01275013 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,138E-03 0,01269191 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,138E-03 0,01263422 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,138E-03 0,01257705 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,138E-03 0,0125204 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 1,000 1,138E-03 0,01246425 ! DNA topological change GO:0006265 12 8 1,000 1,138E-03 0,01240861 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 1,138E-03 0,01235346 ! response to tumor cell GO:0002347 16 8 1,000 1,138E-03 0,0122988 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 1,138E-03 0,01224462 GO:0002688|regulation of leukocyte chemotaxis, ! myeloid cell homeostasis GO:0002262 15 8 1,000 1,138E-03 0,01219091 ! blastocyst growth GO:0001832 19 8 1,000 1,138E-03 0,01213768 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,138E-03 0,01208491 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 1,000 1,138E-03 0,01203259 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,138E-03 0,01198073 ! metanephros development GO:0001656 81 32 2,000 1,155E-03 0,01210781 ! response to mechanical stimulus GO:0009612 60 32 2,000 1,155E-03 0,01205606 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 1,155E-03 0,01200476 ! actin filament organization GO:0007015 167 72 3,000 1,245E-03 0,01288959 ! regulation of pH GO:0006885 56 33 2,000 1,264E-03 0,01303163 ! response to ionizing radiation GO:0010212 74 33 2,000 1,264E-03 0,01297687 ! negative regulation of protein transport GO:0051224 74 33 2,000 1,264E-03 0,01292258 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 1,379E-03 0,01403388 ! organelle localization GO:0051640 155 74 3,000 1,379E-03 0,01397565 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 1,38E-03 0,01393101 ! serine family amino acid metabolic process GO:0009069 56 34 2,000 1,38E-03 0,01387368 ! regulation of transcription factor activity GO:0051090 137 75 3,000 1,449E-03 0,01450835 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 3,000 1,449E-03 0,01444913 ! microtubule bundle formation GO:0001578 22 9 1,000 1,457E-03 0,01446522 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,457E-03 0,01440665 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 1,457E-03 0,01434856 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,457E-03 0,01429094 ! receptor clustering GO:0043113 20 9 1,000 1,457E-03 0,01423377 ! erythrocyte development GO:0048821 17 9 1,000 1,457E-03 0,01417706 ! postreplication repair GO:0006301 25 9 1,000 1,457E-03 0,01412081 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,457E-03 0,01406499 ! calcium-mediated signaling GO:0019722 67 35 2,000 1,502E-03 0,0144483 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 1,502E-03 0,01439164 ! regulation of catabolic process GO:0009894 173 77 3,000 1,597E-03 0,01524228 ! response to steroid hormone stimulus GO:0048545 147 79 3,000 1,756E-03 0,01668862 ! protein oligomerization GO:0051259 149 79 3,000 1,756E-03 0,01662394 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 1,766E-03 0,01666221 ! cell junction organization GO:0034330 96 37 2,000 1,766E-03 0,01659812 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,766E-03 0,01653453 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,813E-03 0,01690496 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,813E-03 0,01684069 ! lung alveolus development GO:0048286 26 10 1,000 1,813E-03 0,01677689 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,813E-03 0,01671359 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,813E-03 0,01665075 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 1,813E-03 0,01658839 ! multicellular organism growth GO:0035264 19 10 1,000 1,813E-03 0,01652649 ! motor axon guidance GO:0008045 22 10 1,000 1,813E-03 0,01646506 ! regulation of bone resorption GO:0045124 25 10 1,000 1,813E-03 0,01640408 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,813E-03 0,01634354 GO:0045685|regulation of glial cell differentiation, ! base-excision repair, AP site formation GO:0006285 15 10 1,000 1,813E-03 0,01628346 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 1,813E-03 0,01622381 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 1,813E-03 0,0161646 ! salivary gland development GO:0007431 28 10 1,000 1,813E-03 0,01610582 ! positive regulation of acute inflammatory response GO:0002675 18 10 1,000 1,813E-03 0,01604746 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 1,813E-03 0,01598953 ! blastocyst formation GO:0001825 18 10 1,000 1,813E-03 0,01593202 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,813E-03 0,01587491 ! development of primary sexual characteristics GO:0045137 143 80 3,000 1,839E-03 0,01604317 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,909E-03 0,01659502 ! carbohydrate homeostasis GO:0033500 59 39 2,000 2,058E-03 0,01782929 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 2,058E-03 0,01776629 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to drug GO:0042493 149 83 3,000 2,104E-03 0,01810305 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 1,000 2,206E-03 0,0189133 ! neuron fate specification GO:0048665 18 11 1,000 2,206E-03 0,01884717 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,206E-03 0,0187815 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,206E-03 0,01871628 ! blood vessel remodeling GO:0001974 30 11 1,000 2,206E-03 0,01865152 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 2,206E-03 0,01858721 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,206E-03 0,01852333 ! negative regulation of proteolysis GO:0045861 25 11 1,000 2,206E-03 0,0184599 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,206E-03 0,01839689 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 2,206E-03 0,01833432 ! nitric oxide metabolic process GO:0046209 17 11 1,000 2,206E-03 0,01827217 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 2,206E-03 0,01821044 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 25 11 1,000 2,206E-03 0,01814912 ! apical protein localization GO:0045176 18 11 1,000 2,206E-03 0,01808822 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 1,000 2,206E-03 0,01802772 ! oocyte development GO:0048599 20 11 1,000 2,206E-03 0,01796763 ! mammary gland development GO:0030879 93 40 2,000 2,214E-03 0,01797267 ! nucleus organization GO:0006997 73 40 2,000 2,214E-03 0,01791316 ! negative regulation of growth GO:0045926 168 85 3,000 2,296E-03 0,01850936 ! monovalent inorganic cation homeostasis GO:0055067 72 41 2,000 2,378E-03 0,01910926 ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,549E-03 0,02041462 ! cytokinesis GO:0000910 84 42 2,000 2,549E-03 0,0203479 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 2,636E-03 0,02097985 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,636E-03 0,02091173 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,636E-03 0,02084406 ! hippocampus development GO:0021766 29 12 1,000 2,636E-03 0,02077682 ! ventral spinal cord development GO:0021517 25 12 1,000 2,636E-03 0,02071001 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 1,000 2,636E-03 0,02064363 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 2,636E-03 0,02057768 ! focal adhesion formation GO:0048041 37 12 1,000 2,636E-03 0,02051215 ! entry into host cell GO:0030260 34 12 1,000 2,636E-03 0,02044703 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 2,636E-03 0,02038232 ! autonomic nervous system development GO:0048483 24 12 1,000 2,636E-03 0,02031802 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,636E-03 0,02025413 ! oocyte differentiation GO:0009994 21 12 1,000 2,636E-03 0,02019064 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 2,636E-03 0,02012754 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 2,636E-03 0,02006484 ! defense response to Gram-positive bacterium GO:0050830 14 12 1,000 2,636E-03 0,02000253 ! embryonic placenta development GO:0001892 21 12 1,000 2,636E-03 0,0199406 ! response to cold GO:0009409 17 12 1,000 2,636E-03 0,01987906 ! localization within membrane GO:0051668 26 12 1,000 2,636E-03 0,01981789 ! regulation of DNA binding GO:0051101 167 89 3,000 2,713E-03 0,02033309 ! positive regulation of transcription factor activity GO:0051091 71 43 2,000 2,727E-03 0,02037236 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 2,000 2,727E-03 0,02031025 ! regulation of T cell proliferation GO:0042129 80 43 2,000 2,727E-03 0,02024852 ! positive regulation of protein modification process GO:0031401 156 90 3,000 2,825E-03 0,02091578 ! double-strand break repair GO:0006302 85 44 2,000 2,913E-03 0,02149662 ! gland development GO:0048732 220 91 3,000 2,94E-03 0,02163692 ! regulation of chemokine production GO:0032642 18 13 1,000 3,103E-03 0,02276122 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 3,103E-03 0,02269307 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 25 13 1,000 3,103E-03 0,02262533 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 3,103E-03 0,022558 ! exocrine system development GO:0035272 34 13 1,000 3,103E-03 0,02249106 ! asymmetric protein localization GO:0008105 24 13 1,000 3,103E-03 0,02242452 ! membrane protein proteolysis GO:0033619 33 13 1,000 3,103E-03 0,02235837 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,103E-03 0,02229261 ! gland morphogenesis GO:0022612 31 13 1,000 3,103E-03 0,02222723 ! regulation of acute inflammatory response GO:0002673 24 13 1,000 3,103E-03 0,02216224 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 1,000 3,103E-03 0,02209763 ! regulation of mRNA stability GO:0043488 32 13 1,000 3,103E-03 0,02203339 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 3,103E-03 0,02196953 ! developmental growth GO:0048589 88 45 2,000 3,106E-03 0,02192937 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 3,18E-03 0,0223898 ! response to insulin stimulus GO:0032868 98 47 2,000 3,516E-03 0,02467977 ! sex differentiation GO:0007548 171 96 3,000 3,564E-03 0,0249506 ! regulation of S phase GO:0033261 26 14 1,000 3,604E-03 0,02515752 ! deoxyribonucleotide catabolic process GO:0009264 21 14 1,000 3,604E-03 0,02508585 ! bone mineralization GO:0030282 18 14 1,000 3,604E-03 0,02501458 ! regulation of cellular pH GO:0030641 27 14 1,000 3,604E-03 0,02494372 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 1,000 3,604E-03 0,02487326 ! regulation of T-helper 2 type immune response GO:0002828 25 14 1,000 3,604E-03 0,02480319 ! regulation of RNA stability GO:0043487 33 14 1,000 3,604E-03 0,02473352 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 3,699E-03 0,02531356 ! positive regulation of DNA binding GO:0043388 83 48 2,000 3,732E-03 0,02546883 ! male sex differentiation GO:0046661 93 48 2,000 3,732E-03 0,02539788 ! leukocyte differentiation GO:0002521 232 98 3,000 3,837E-03 0,02604017 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 3,957E-03 0,02677728 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,141E-03 0,02794638 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 4,141E-03 0,02786939 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 1,000 4,141E-03 0,02779283 ! regulation of mRNA processing GO:0050684 26 15 1,000 4,141E-03 0,02771668 ! glycoprotein catabolic process GO:0006516 33 15 1,000 4,141E-03 0,02764095 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 4,141E-03 0,02756564 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 4,141E-03 0,02749073 ! G1/S transition checkpoint GO:0031575 37 15 1,000 4,141E-03 0,02741623 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 4,141E-03 0,02734213 ! dopamine metabolic process GO:0042417 35 15 1,000 4,141E-03 0,02726844 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 4,19E-03 0,02751358 ! activation of caspase activity GO:0006919 95 50 2,000 4,19E-03 0,02743981 ! regulation of cell projection organization GO:0031344 135 51 2,000 4,43E-03 0,02893957 ! positive regulation of binding GO:0051099 88 52 2,000 4,679E-03 0,03048493 ! response to estrogen stimulus GO:0043627 98 52 2,000 4,679E-03 0,03040385 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 4,679E-03 0,03032321 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 4,679E-03 0,03024299 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 4,713E-03 0,03037653 ! regulation of neurotransmitter secretion GO:0046928 35 16 1,000 4,713E-03 0,03029659 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 4,713E-03 0,03021707 ! biomineral formation GO:0031214 22 16 1,000 4,713E-03 0,03013797 ! regulation of T-helper cell differentiation GO:0045622 30 16 1,000 4,713E-03 0,03005928 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 4,713E-03 0,029981 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,713E-03 0,02990313 ! cartilage development GO:0051216 99 53 2,000 4,937E-03 0,03124504 ! regulation of muscle contraction GO:0006937 94 54 2,000 5,203E-03 0,03284187 ! membrane fusion GO:0006944 122 54 2,000 5,203E-03 0,03275722 ! negative regulation of hormone secretion GO:0046888 26 17 1,000 5,318E-03 0,03339932 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 5,318E-03 0,03331368 ! signal complex assembly GO:0007172 47 17 1,000 5,318E-03 0,03322848 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 5,318E-03 0,03314372 ! activation of MAPKK activity GO:0000186 43 17 1,000 5,318E-03 0,03305938 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 5,318E-03 0,03297547 ! regulation of survival gene product expression GO:0045884 38 17 1,000 5,318E-03 0,03289199 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 5,318E-03 0,03280893 GO:0031114|regulation of microtubule depolymerization, ! DNA unwinding during replication GO:0006268 26 17 1,000 5,318E-03 0,03272629 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 1,000 5,318E-03 0,03264406 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 5,318E-03 0,03256225 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 5,318E-03 0,03248084 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 5,318E-03 0,03239984 ! regulation of DNA replication GO:0006275 105 56 2,000 5,759E-03 0,03500095 ! positive regulation of anti-apoptosis GO:0045768 47 18 1,000 5,958E-03 0,03611503 ! limbic system development GO:0021761 40 18 1,000 5,958E-03 0,03602564 ! regulation of viral genome replication GO:0045069 30 18 1,000 5,958E-03 0,03593668 ! centrosome cycle GO:0007098 26 18 1,000 5,958E-03 0,03584817 ! cell-substrate junction assembly GO:0007044 56 18 1,000 5,958E-03 0,03576009 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 5,958E-03 0,03567244 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 5,958E-03 0,03558523 ! neural crest cell migration GO:0001755 41 18 1,000 5,958E-03 0,03549843 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 5,958E-03 0,03541206 ! defense response to virus GO:0051607 43 18 1,000 5,958E-03 0,03532611 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 5,958E-03 0,03524057 ! regulation of bone remodeling GO:0046850 143 57 2,000 6,051E-03 0,03570552 ! positive regulation of caspase activity GO:0043280 108 57 2,000 6,051E-03 0,03561949 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 2,000 6,051E-03 0,03553386 ! aging GO:0007568 112 58 2,000 6,351E-03 0,03720612 ! regulation of tissue remodeling GO:0034103 146 58 2,000 6,351E-03 0,03711711 ! positive regulation of translation GO:0045727 31 19 1,000 6,63E-03 0,03865787 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 1,000 6,63E-03 0,03856582 GO:0019692|deoxyribose phosphate metabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 1,000 6,63E-03 0,03847422 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 6,63E-03 0,03838305 ! pigmentation during development GO:0048066 42 19 1,000 6,63E-03 0,03829231 ! neuromuscular junction development GO:0007528 43 19 1,000 6,63E-03 0,038202 ! response to lipopolysaccharide GO:0032496 34 19 1,000 6,63E-03 0,03811211 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 6,63E-03 0,03802264 ! cellular pigmentation GO:0033059 37 19 1,000 6,63E-03 0,0379336 ! proximal/distal pattern formation GO:0009954 33 19 1,000 6,63E-03 0,03784497 ! peptide hormone secretion GO:0030072 32 19 1,000 6,63E-03 0,03775675 ! DNA catabolic process GO:0006308 94 60 2,000 6,977E-03 0,03963906 ! kidney development GO:0001822 133 60 2,000 6,977E-03 0,03954709 ! regulation of heart contraction GO:0008016 123 61 2,000 7,303E-03 0,04130107 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 7,303E-03 0,04120569 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 7,336E-03 0,04129285 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,336E-03 0,04119792 ! protein amino acid acetylation GO:0006473 41 20 1,000 7,336E-03 0,04110343 ! response to alkaloid GO:0043279 38 20 1,000 7,336E-03 0,04100938 ! DNA duplex unwinding GO:0032508 30 20 1,000 7,336E-03 0,04091575 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 7,336E-03 0,04082254 ! actin filament bundle formation GO:0051017 47 20 1,000 7,336E-03 0,04072977 ! peptide secretion GO:0002790 38 20 1,000 7,336E-03 0,04063741 ! cell-cell junction organization GO:0045216 43 20 1,000 7,336E-03 0,04054547 ! negative regulation of T cell activation GO:0050868 41 20 1,000 7,336E-03 0,04045394 ! negative regulation of translation GO:0017148 32 20 1,000 7,336E-03 0,04036283 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 7,639E-03 0,04193502 ! regulation of homeostatic process GO:0032844 148 62 2,000 7,639E-03 0,04184099 ! regulation of protein complex assembly GO:0043254 132 63 2,000 7,983E-03 0,04362861 ! mesoderm development GO:0007498 128 63 2,000 7,983E-03 0,04353123 ! hormone secretion GO:0046879 39 21 1,000 8,074E-03 0,04392787 ! lipid phosphorylation GO:0046834 43 21 1,000 8,074E-03 0,04383025 ! regulation of neurotransmitter transport GO:0051588 44 21 1,000 8,074E-03 0,04373306 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 8,074E-03 0,04363631 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 8,074E-03 0,04353998 ! plasma membrane fusion GO:0045026 33 21 1,000 8,074E-03 0,04344408 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 8,074E-03 0,0433486 ! prostaglandin metabolic process GO:0006693 43 21 1,000 8,074E-03 0,04325353 GO:0006692|prostanoid metabolic process, ! negative regulation of angiogenesis GO:0016525 49 21 1,000 8,074E-03 0,04315889 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 8,074E-03 0,04306465 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 8,074E-03 0,04297083 ! collagen catabolic process GO:0030574 29 21 1,000 8,074E-03 0,04287742 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 8,074E-03 0,04278441 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 8,336E-03 0,04407989 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 8,843E-03 0,04666113 ! cellular response to starvation GO:0009267 37 22 1,000 8,843E-03 0,04656057 ! D-ribose metabolic process GO:0006014 36 22 1,000 8,843E-03 0,04646044 ! ureteric bud development GO:0001657 50 22 1,000 8,843E-03 0,04636074 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 8,843E-03 0,04626147 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 8,843E-03 0,04616262 ! peptidyl-serine modification GO:0018209 50 22 1,000 8,843E-03 0,04606419 ! gut development GO:0048565 44 22 1,000 8,843E-03 0,04596618 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 8,843E-03 0,04586859 ! protein stabilization GO:0050821 41 22 1,000 8,843E-03 0,04577141 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 9,07E-03 0,04684415 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 9,07E-03 0,04674532 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 9,07E-03 0,04664691 ! regulation of anti-apoptosis GO:0045767 62 23 1,000 9,644E-03 0,04949895 ! gluconeogenesis GO:0006094 38 23 1,000 9,644E-03 0,04939518 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 9,644E-03 0,04929184 ! deoxyribonucleotide metabolic process GO:0009262 37 23 1,000 9,644E-03 0,04918894 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 9,644E-03 0,04908646 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 9,644E-03 0,04898441 ! regulation of interleukin-6 production GO:0032675 31 23 1,000 9,644E-03 0,04888278 ! hormone transport GO:0009914 41 23 1,000 9,644E-03 0,04878157 ! viral reproduction GO:0016032 142 68 2,000 9,84E-03 0,04966759 ! lung development GO:0030324 165 69 2,000 0,01023899 0,05157494 ! homeostasis of number of cells GO:0048872 131 69 2,000 0,01023899 0,05146882 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 0,01047676 0,05255592 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 0,01047676 0,05244822 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 0,01047676 0,05234097 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 0,01047676 0,05223415 ! regulation of viral reproduction GO:0050792 41 24 1,000 0,01047676 0,05212777 ! pallium development GO:0021543 56 24 1,000 0,01047676 0,05202181 ! oogenesis GO:0048477 44 24 1,000 0,01047676 0,05191629 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 0,01047676 0,0518112 ! platelet activation GO:0030168 41 24 1,000 0,01047676 0,05170653 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 0,01047676 0,05160228 ! germ cell development GO:0007281 133 70 2,000 0,01064726 0,05233652 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 0,01106484 0,05427995 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 0,01133964 0,05551653 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 0,01133964 0,0554055 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 0,01133964 0,05529491 ! receptor metabolic process GO:0043112 53 25 1,000 0,01133964 0,05518476 ! chromosome condensation GO:0030261 48 25 1,000 0,01133964 0,05507505 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 0,01133964 0,05496577 ! interaction with host GO:0051701 66 25 1,000 0,01133964 0,05485693 ! positive regulation of protein secretion GO:0050714 41 25 1,000 0,01133964 0,05474852 ! leukocyte homeostasis GO:0001776 50 25 1,000 0,01133964 0,05464053 ! protein tetramerization GO:0051262 57 25 1,000 0,01133964 0,05453297 ! respiratory tube development GO:0030323 171 72 2,000 0,01149179 0,05515606 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 0,01223271 0,05859706 ! myelination GO:0042552 50 26 1,000 0,01223271 0,05848239 ! initiation of viral infection GO:0019059 60 26 1,000 0,01223271 0,05836817 ! pyruvate metabolic process GO:0006090 43 26 1,000 0,01223271 0,05825439 ! molting cycle process GO:0022404 52 26 1,000 0,01223271 0,05814106 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! microtubule organizing center organization GO:0031023 42 26 1,000 0,01223271 0,05802816 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 1,000 0,01223271 0,0579157 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 0,01223271 0,05780368 ! neural crest cell development GO:0014032 59 26 1,000 0,01223271 0,05769209 GO:0014033|neural crest cell differentiation, ! pentose metabolic process GO:0019321 43 26 1,000 0,01223271 0,05758093 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 0,01223271 0,0574702 ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01223271 0,05735989 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 0,01223271 0,05725001 ! respiratory system development GO:0060541 175 74 2,000 0,01237387 0,05779993 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 0,01282907 0,05981186 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01315553 0,06121707 ! multicellular organismal catabolic process GO:0044243 38 27 1,000 0,01315553 0,06110069 ! response to toxin GO:0009636 49 27 1,000 0,01315553 0,06098475 ! cellular response to nutrient levels GO:0031669 45 27 1,000 0,01315553 0,06086925 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 0,01315553 0,06075418 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,01315553 0,06063955 ! response to starvation GO:0042594 47 27 1,000 0,01315553 0,06052535 ! cellular response to oxidative stress GO:0034599 43 27 1,000 0,01315553 0,06041158 ! cell-matrix adhesion GO:0007160 181 76 2,000 0,01329375 0,06093176 ! neuron fate commitment GO:0048663 52 28 1,000 0,0141077 0,06454139 ! protein amino acid acylation GO:0043543 59 28 1,000 0,0141077 0,06442075 ! circadian rhythm GO:0007623 56 28 1,000 0,0141077 0,06430056 ! dendrite development GO:0016358 67 28 1,000 0,0141077 0,06418082 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 0,0141077 0,06406153 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 0,0141077 0,06394267 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 0,01425164 0,06447549 ! regulation of synaptic transmission GO:0050804 159 79 2,000 0,01474491 0,06658375 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01508879 0,0680109 ! catechol metabolic process GO:0009712 55 29 1,000 0,01508879 0,06788565 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 0,01508879 0,06776086 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01508879 0,06763653 ! somitogenesis GO:0001756 52 29 1,000 0,01508879 0,06751265 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01508879 0,06738923 ! negative regulation of organelle organization GO:0010639 181 80 2,000 0,01524774 0,06797489 ! meiosis GO:0007126 143 81 2,000 0,01576017 0,07013134 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 2,000 0,01576017 0,07000383 ! response to hypoxia GO:0001666 178 81 2,000 0,01576017 0,06987678 ! phenol metabolic process GO:0018958 56 30 1,000 0,0160984 0,07124706 ! icosanoid biosynthetic process GO:0046456 60 30 1,000 0,0160984 0,07111823 ! acute-phase response GO:0006953 50 30 1,000 0,0160984 0,07098985 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,0160984 0,07086195 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 0,0160984 0,0707345 GO:0048871|multicellular organismal homeostasis, ! cell-substrate adhesion GO:0031589 189 82 2,000 0,01628221 0,07141373 ! meiotic cell cycle GO:0051321 144 82 2,000 0,01628221 0,07128575 ! exocytosis GO:0006887 153 83 2,000 0,01681388 0,07348176 ! response to oxygen levels GO:0070482 183 83 2,000 0,01681388 0,07335054 ! cell junction assembly GO:0034329 85 31 1,000 0,01713611 0,07462303 ! peptide transport GO:0015833 60 31 1,000 0,01713611 0,07449025 ! male gonad development GO:0008584 56 31 1,000 0,01713611 0,07435794 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01713611 0,0742261 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01713611 0,07409473 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01713611 0,07396382 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01713611 0,07383337 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01713611 0,07370338 ! regulation of neuron differentiation GO:0045664 187 85 2,000 0,01790614 0,07687996 ! regulation of transmission of nerve impulse GO:0051969 167 85 2,000 0,01790614 0,07674509 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 0,01790614 0,07661068 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 0,01820153 0,07773837 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01820153 0,0776027 ! collagen metabolic process GO:0032963 49 32 1,000 0,01820153 0,0774675 ! spindle organization GO:0007051 50 32 1,000 0,01820153 0,07733278 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,01820153 0,07719852 ! hexose biosynthetic process GO:0019319 53 32 1,000 0,01820153 0,07706473 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01820153 0,0769314 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,01820153 0,07679853 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01820153 0,07666612 ! positive regulation of cell activation GO:0050867 161 86 2,000 0,01846676 0,07764939 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 2,000 0,01903706 0,07990984 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01929426 0,08085058 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 1,000 0,01929426 0,08071213 ! amine biosynthetic process GO:0009309 146 88 2,000 0,01961703 0,08192207 ! regulation of neurological system process GO:0031644 175 89 2,000 0,0202067 0,08424055 ! glial cell differentiation GO:0010001 67 34 1,000 0,02041391 0,08495941 ! cell fate specification GO:0001708 56 34 1,000 0,02041391 0,08481492 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,02041391 0,08467092 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,02080606 0,08615118 ! ossification GO:0001503 205 91 2,000 0,02141511 0,08852305 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,02156007 0,08897171 ! negative regulation of secretion GO:0051048 68 35 1,000 0,02156007 0,08882167 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,02156007 0,08867214 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 0,02156007 0,08852311 ! telencephalon development GO:0021537 81 35 1,000 0,02156007 0,08837458 ! placenta development GO:0001890 53 35 1,000 0,02156007 0,08822655 ! bone development GO:0060348 206 92 2,000 0,02203387 0,09001461 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,02203387 0,08986434 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,02273237 0,09255863 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,02273237 0,09240462 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,02273237 0,09225113 ! regulation of proteolysis GO:0030162 77 36 1,000 0,02273237 0,09209814 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,02273237 0,09194566 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 1,000 0,02273237 0,09179368 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,02273237 0,09164221 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,02393042 0,09631304 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,02393042 0,09615463 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,02393042 0,09599674 ! sister chromatid segregation GO:0000819 65 37 1,000 0,02393042 0,09583937 ! tissue remodeling GO:0048771 78 37 1,000 0,02393042 0,09568251 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,02393042 0,09552617 ! female gonad development GO:0008585 71 37 1,000 0,02393042 0,09537034 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,02393042 0,09521501 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,02393042 0,09506019 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 0,02394833 0,0949769 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02460588 0,09742651 ! meiosis I GO:0007127 74 38 1,000 0,02515384 0,09943501 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,02515384 0,09927438 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,02515384 0,09911426 ! regulation of protein stability GO:0031647 77 38 1,000 0,02515384 0,09895465 ! glycogen metabolic process GO:0005977 63 38 1,000 0,02515384 0,09879556 ! negative regulation of binding GO:0051100 71 39 1,000 0,02640226 0,10353247 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,02640226 0,10336655 ! nucleotide catabolic process GO:0009166 70 39 1,000 0,02640226 0,10320117 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,02640226 0,10303631 ! glucan metabolic process GO:0044042 64 39 1,000 0,02640226 0,10287198 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 82 40 1,000 0,02767531 0,10766048 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,02767531 0,10748932 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 1,000 0,02767531 0,1073187 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02767531 0,10714862 ! gliogenesis GO:0042063 91 41 1,000 0,02897261 0,11199381 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,02897261 0,11181689 ! maintenance of protein location GO:0045185 95 41 1,000 0,02897261 0,11164052 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,02897261 0,11146471 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,03029381 0,11636442 ! ear morphogenesis GO:0042471 64 42 1,000 0,03029381 0,11618175 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,03029381 0,11599964 ! T cell differentiation GO:0030217 93 42 1,000 0,03029381 0,11581811 ! regulation of protein secretion GO:0050708 77 42 1,000 0,03029381 0,11563714 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,03029381 0,11545674 ! glucose transport GO:0015758 66 43 1,000 0,03163854 0,12039399 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,03163854 0,12020675 ! segmentation GO:0035282 78 43 1,000 0,03163854 0,1200201 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03194002 0,12097592 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03194002 0,12078865 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03194002 0,12060196 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03194002 0,12041585 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03194002 0,12023031 ! neuron fate determination GO:0048664 7 5 0,000 0,03194002 0,12004534 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03194002 0,11986094 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03194002 0,1196771 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03194002 0,11949383 ! polyol transport GO:0015791 12 5 0,000 0,03194002 0,11931112 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03194002 0,11912896 ! response to superoxide GO:0000303 10 5 0,000 0,03194002 0,11894736 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03194002 0,11876632 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03194002 0,11858582 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03194002 0,11840587 ! female meiosis GO:0007143 10 5 0,000 0,03194002 0,11822647 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,03194002 0,11804761 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03194002 0,11786929 ! hypothalamus development GO:0021854 9 5 0,000 0,03194002 0,11769151 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03194002 0,11751426 ! cobalt ion transport GO:0006824 11 5 0,000 0,03194002 0,11733755 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03194002 0,11716137 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03194002 0,11698571 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03194002 0,11681058 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03194002 0,11663598 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03194002 0,1164619 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03194002 0,11628833 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03194002 0,11611528 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03194002 0,11594275 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! transposition GO:0032196 9 5 0,000 0,03194002 0,11577073 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,03194002 0,11559921 ! negative chemotaxis GO:0050919 16 5 0,000 0,03194002 0,11542821 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03194002 0,11525771 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03194002 0,11508771 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03194002 0,11491822 ! behavioral response to pain GO:0048266 10 5 0,000 0,03194002 0,11474922 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03194002 0,11458072 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03194002 0,11441271 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03194002 0,1142452 ! micturition GO:0060073 9 5 0,000 0,03194002 0,11407817 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03194002 0,11391164 ! copulation GO:0007620 9 5 0,000 0,03194002 0,11374558 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03194002 0,11358001 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03194002 0,11341493 ! bioluminescence GO:0008218 9 5 0,000 0,03194002 0,11325032 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03194002 0,11308619 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03194002 0,11292253 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03194002 0,11275935 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03194002 0,11259664 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03194002 0,11243439 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03194002 0,11227262 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03194002 0,11211131 ! grooming behavior GO:0007625 6 5 0,000 0,03194002 0,11195046 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03194002 0,11179007 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03194002 0,11163014 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03194002 0,11147067 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03194002 0,11131165 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,03194002 0,11115309 ! lymph vessel development GO:0001945 10 5 0,000 0,03194002 0,11099498 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03194002 0,11083732 ! endochondral ossification GO:0001958 17 5 0,000 0,03194002 0,1106801 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03194002 0,11052333 ! single strand break repair GO:0000012 8 5 0,000 0,03194002 0,110367 ! parathyroid gland development GO:0060017 14 5 0,000 0,03194002 0,11021112 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03194002 0,11005567 ! cytokine secretion GO:0050663 15 5 0,000 0,03194002 0,10990066 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03194002 0,10974609 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03194002 0,10959195 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03194002 0,10943825 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03194002 0,10928497 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03194002 0,10913213 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03194002 0,10897971 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03194002 0,10882771 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03194002 0,10867614 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,03194002 0,10852499 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03194002 0,10837426 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03194002 0,10822395 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03194002 0,10807406 ! valine metabolic process GO:0006573 12 5 0,000 0,03194002 0,10792458 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03194002 0,10777551 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03194002 0,10762686 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03194002 0,10747861 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03194002 0,10733077 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03194002 0,10718334 ! polyol catabolic process GO:0046174 9 5 0,000 0,03194002 0,10703631 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03194002 0,10688968 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03194002 0,10674346 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03194002 0,10659764 ! muscle cell migration GO:0014812 8 5 0,000 0,03194002 0,10645221 ! mitochondrial fission GO:0000266 8 5 0,000 0,03194002 0,10630718 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03194002 0,10616254 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03194002 0,1060183 ! mRNA transcription GO:0009299 10 5 0,000 0,03194002 0,10587445 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03194002 0,10573099 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03194002 0,10558792 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03194002 0,10544523 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03194002 0,10530293 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03194002 0,10516101 ! monocyte activation GO:0042117 10 5 0,000 0,03194002 0,10501948 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03194002 0,10487832 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03194002 0,10473754 ! response to food GO:0032094 6 5 0,000 0,03194002 0,10459714 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03194002 0,10445712 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03194002 0,10431747 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03194002 0,1041782 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03194002 0,10403929 ! forebrain neuron development GO:0021884 13 5 0,000 0,03194002 0,10390076 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03194002 0,10376259 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03194002 0,10362479 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03194002 0,10348736 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03194002 0,10335029 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03194002 0,10321358 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03194002 0,10307724 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03194002 0,10294125 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03194002 0,10280563 ! lipid glycosylation GO:0030259 7 5 0,000 0,03194002 0,10267036 ! nucleobase transport GO:0015851 6 5 0,000 0,03194002 0,10253544 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03194002 0,10240088 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03194002 0,10226667 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03194002 0,10213281 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03194002 0,10199931 ! basic amino acid transport GO:0015802 12 5 0,000 0,03194002 0,10186615 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03194002 0,10173334 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03194002 0,10160087 ! actin nucleation GO:0045010 11 5 0,000 0,03194002 0,10146875 ! depurination GO:0045007 5 5 0,000 0,03194002 0,10133697 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03194002 0,10120554 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03194002 0,10107444 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03194002 0,10094369 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03194002 0,10081327 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03194002 0,10068319 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03194002 0,10055344 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03194002 0,10042403 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03194002 0,10029495 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03194002 0,1001662 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03194002 0,10003778 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03194002 0,09990969 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03194002 0,09978193 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03194002 0,0996545 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03194002 0,09952739 ! response to arsenic GO:0046685 11 5 0,000 0,03194002 0,0994006 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03194002 0,09927413 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03194002 0,09914799 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03194002 0,09902217 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03194002 0,09889667 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03194002 0,09877148 ! response to mercury ion GO:0046689 8 5 0,000 0,03194002 0,09864661 ! response to cadmium ion GO:0046686 7 5 0,000 0,03194002 0,09852206 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03194002 0,09839782 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03194002 0,09827389 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03194002 0,09815028 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03194002 0,09802697 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03194002 0,09790398 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03194002 0,09778129 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03194002 0,09765891 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03194002 0,09753684 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03194002 0,09741507 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03194002 0,0972936 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03194002 0,09717244 ! embryonic cleavage GO:0040016 6 5 0,000 0,03194002 0,09705158 ! peroxisome fission GO:0016559 5 5 0,000 0,03194002 0,09693102 ! histone demethylation GO:0016577 13 5 0,000 0,03194002 0,09681076 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03194002 0,09669079 ! mitotic recombination GO:0006312 9 5 0,000 0,03194002 0,09657113 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03194002 0,09645176 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03194002 0,09633268 ! metaphase plate congression GO:0051310 7 5 0,000 0,03194002 0,0962139 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03194002 0,09609541 GO:0032374|regulation of cholesterol transport, ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03194002 0,09597721 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03194002 0,0958593 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03194002 0,09574168 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03194002 0,09562435 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03194002 0,09550731 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03194002 0,09539055 ! B cell homeostasis GO:0001782 13 5 0,000 0,03194002 0,09527408 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03194002 0,09515789 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03194002 0,09504199 ! metaphase GO:0051323 11 5 0,000 0,03194002 0,09492636 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03194002 0,09481102 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03194002 0,09469596 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03194002 0,09458118 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03194002 0,09446667 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03194002 0,09435244 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03194002 0,09423849 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03194002 0,09412481 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03194002 0,09401141 ! response to redox state GO:0051775 6 5 0,000 0,03194002 0,09389828 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03194002 0,09378542 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03194002 0,09367283 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03194002 0,09356052 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03194002 0,09344847 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03194002 0,09333669 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03194002 0,09322517 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03194002 0,09311393 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03194002 0,09300294 GO:0033015|tetrapyrrole catabolic process, ! striatum development GO:0021756 14 5 0,000 0,03194002 0,09289223 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03194002 0,09278177 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03194002 0,09267158 ! glial cell migration GO:0008347 10 5 0,000 0,03194002 0,09256165 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03194002 0,09245198 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03194002 0,09234257 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03194002 0,09223342 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03194002 0,09212452 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03194002 0,09201588 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03194002 0,0919075 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03194002 0,09179938 ! neuroprotection GO:0043526 8 5 0,000 0,03194002 0,0916915 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03194002 0,09158388 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03194002 0,09147652 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03194002 0,0913694 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03194002 0,09126254 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03194002 0,09115592 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03194002 0,09104956 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03194002 0,09094344 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03194002 0,09083757 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03194002 0,09073194 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03194002 0,09062656 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03194002 0,09052143 ! spindle assembly GO:0051225 6 5 0,000 0,03194002 0,09041654 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03194002 0,09031189 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03194002 0,09020748 ! protein palmitoylation GO:0018345 12 5 0,000 0,03194002 0,09010331 ! drug metabolic process GO:0017144 7 5 0,000 0,03194002 0,08999939 ! stem cell division GO:0017145 11 5 0,000 0,03194002 0,0898957 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,03194002 0,08979226 ! organ regeneration GO:0031100 7 5 0,000 0,03194002 0,08968905 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03194002 0,08958607 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03194002 0,08948334 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,03300644 0,0923651 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,03300644 0,09225942 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,03300644 0,09215398 ! hexose transport GO:0008645 68 44 1,000 0,03300644 0,09204878 GO:0015749|monosaccharide transport, ! phagocytosis GO:0006909 105 44 1,000 0,03300644 0,09194382 ! biopolymer methylation GO:0043414 91 45 1,000 0,03439717 0,09570874 ! B cell differentiation GO:0030183 124 45 1,000 0,03439717 0,09559986 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,03439717 0,09549122 ! female gamete generation GO:0007292 71 45 1,000 0,03439717 0,09538283 ! maintenance of location in cell GO:0051651 101 45 1,000 0,03439717 0,09527469 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,03581036 0,09907669 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,03581036 0,09896461 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03820508 0,10546328 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03820508 0,10534424 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03820508 0,10522548 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03820508 0,10510698 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03820508 0,10498875 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03820508 0,10487079 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03820508 0,10475309 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03820508 0,10463565 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03820508 0,10451848 ! response to oxygen radical GO:0000305 11 6 0,000 0,03820508 0,10440157 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03820508 0,10428492 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03820508 0,10416853 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03820508 0,1040524 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03820508 0,10393653 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03820508 0,10382091 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03820508 0,10370556 ! forebrain regionalization GO:0021871 9 6 0,000 0,03820508 0,10359045 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03820508 0,10347561 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03820508 0,10336102 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03820508 0,10324668 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03820508 0,1031326 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03820508 0,10301876 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03820508 0,10290518 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03820508 0,10279185 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03820508 0,10267877 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03820508 0,10256593 ! malate metabolic process GO:0006108 13 6 0,000 0,03820508 0,10245335 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03820508 0,10234101 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03820508 0,10222892 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03820508 0,10211707 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03820508 0,10200546 ! protein refolding GO:0042026 15 6 0,000 0,03820508 0,1018941 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03820508 0,10178299 ! opsonization GO:0008228 8 6 0,000 0,03820508 0,10167211 ! mating behavior GO:0007617 7 6 0,000 0,03820508 0,10156148 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03820508 0,10145109 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03820508 0,10134093 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03820508 0,10123102 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03820508 0,10112134 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03820508 0,1010119 ! toxin metabolic process GO:0009404 11 6 0,000 0,03820508 0,1009027 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03820508 0,10079374 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03820508 0,10068501 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03820508 0,10057651 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03820508 0,10046825 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03820508 0,10036021 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03820508 0,10025242 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03820508 0,10014485 ! thymic T cell selection GO:0045061 16 6 0,000 0,03820508 0,10003751 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03820508 0,09993041 ! protein lipoylation GO:0009249 10 6 0,000 0,03820508 0,09982353 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03820508 0,09971688 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03820508 0,09961046 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03820508 0,09950426 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03820508 0,0993983 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03820508 0,09929255 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03820508 0,09918703 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! response to pH GO:0009268 10 6 0,000 0,03820508 0,09908174 ! hyperosmotic response GO:0006972 10 6 0,000 0,03820508 0,09897667 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03820508 0,09887182 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03820508 0,0987672 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03820508 0,09866279 ! urea metabolic process GO:0019627 7 6 0,000 0,03820508 0,09855861 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03820508 0,09845464 ! neutrophil activation GO:0042119 7 6 0,000 0,03820508 0,0983509 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03820508 0,09824737 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03820508 0,09814406 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03820508 0,09804097 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03820508 0,09793809 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03820508 0,09783543 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03820508 0,09773298 ! neuron apoptosis GO:0051402 15 6 0,000 0,03820508 0,09763075 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03820508 0,09752874 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03820508 0,09742693 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03820508 0,09732534 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03820508 0,09722396 ! carnitine transport GO:0015879 10 6 0,000 0,03820508 0,09712279 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03820508 0,09702183 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03820508 0,09692108 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03820508 0,09682054 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03820508 0,09672021 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03820508 0,09662008 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03820508 0,09652017 ! neural nucleus development GO:0048857 19 6 0,000 0,03820508 0,09642045 ! astrocyte development GO:0014002 16 6 0,000 0,03820508 0,09632095 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03820508 0,09622165 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03820508 0,09612255 ! interaction with symbiont GO:0051702 14 6 0,000 0,03820508 0,09602366 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03820508 0,09592497 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03820508 0,09582649 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03820508 0,0957282 ! response to copper ion GO:0046688 10 6 0,000 0,03820508 0,09563012 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03820508 0,09553224 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03820508 0,09543456 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03820508 0,09533708 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03820508 0,0952398 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03820508 0,09514271 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03820508 0,09504582 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03820508 0,09494914 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03820508 0,09485264 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03820508 0,09475634 ! Schwann cell development GO:0014044 15 6 0,000 0,03820508 0,09466024 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03820508 0,09456434 ! response to pheromone GO:0019236 6 6 0,000 0,03820508 0,09446862 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03820508 0,0943731 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03820508 0,09427778 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03820508 0,09418264 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03820508 0,0940877 ! subpallium development GO:0021544 15 6 0,000 0,03820508 0,09399295 ! neural tube patterning GO:0021532 8 6 0,000 0,03820508 0,09389839 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03820508 0,09380402 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03820508 0,09370984 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03820508 0,09361585 ! G2 phase GO:0051319 16 6 0,000 0,03820508 0,09352204 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03820508 0,09342843 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03820508 0,093335 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03820508 0,09324176 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03820508 0,0931487 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03820508 0,09305583 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03820508 0,09296315 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03820508 0,09287065 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03820508 0,09277833 ! receptor internalization GO:0031623 11 6 0,000 0,03820508 0,0926862 ! plasminogen activation GO:0031639 9 6 0,000 0,03820508 0,09259425 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03820508 0,09250248 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 16 6 0,000 0,03820508 0,09241089 ! protein destabilization GO:0031648 9 6 0,000 0,03820508 0,09231949 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03820508 0,09222826 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03820508 0,09213722 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03820508 0,09204635 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03820508 0,09195566 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03820508 0,09186516 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03820508 0,09177483 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03820508 0,09168468 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03820508 0,0915947 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03820508 0,0915049 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03820508 0,09141528 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03820508 0,09132583 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03820508 0,09123656 ! neural plate development GO:0001840 9 6 0,000 0,03820508 0,09114746 ! catecholamine transport GO:0051937 9 6 0,000 0,03820508 0,09105854 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03820508 0,09096979 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03820508 0,09088121 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03820508 0,0907928 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03820508 0,09070457 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03820508 0,0906165 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03820508 0,09052861 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03820508 0,09044089 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03820508 0,09035334 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03820508 0,09026596 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03820508 0,09017874 GO:0055081|anion homeostasis, ! mitochondrial transport GO:0006839 94 48 1,000 0,03870279 0,09126537 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,03870279 0,09117736 ! cellular component disassembly GO:0022411 89 48 1,000 0,03870279 0,09108952 ! endosome transport GO:0016197 127 48 1,000 0,03870279 0,09100185 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,03870279 0,09091435 ! icosanoid metabolic process GO:0006690 92 48 1,000 0,03870279 0,09082702 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,03870279 0,09073985 ! methylation GO:0032259 97 48 1,000 0,03870279 0,09065285 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,04018134 0,09402588 ! protein homooligomerization GO:0051260 84 49 1,000 0,04018134 0,09393591 ! regulation of action potential GO:0001508 102 50 1,000 0,041681 0,09734865 ! endocrine system development GO:0035270 109 50 1,000 0,041681 0,09725567 ! regulation of ossification GO:0030278 123 50 1,000 0,041681 0,09716287 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,041681 0,09707025 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,041681 0,0969778 ! viral infectious cycle GO:0019058 104 51 1,000 0,04320144 0,1004197 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,04320144 0,10032425 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,04320144 0,10022897 ! response to temperature stimulus GO:0009266 84 51 1,000 0,04320144 0,10013388 ! tRNA transcription GO:0009304 17 7 0,000 0,04442976 0,10288332 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04442976 0,10278589 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04442976 0,10268865 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04442976 0,10259159 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04442976 0,10249472 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04442976 0,10239802 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04442976 0,10230151 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04442976 0,10220518 ! prostate gland development GO:0030850 14 7 0,000 0,04442976 0,10210903 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04442976 0,10201307 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04442976 0,10191728 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04442976 0,10182167 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04442976 0,10172625 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04442976 0,101631 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04442976 0,10153592 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04442976 0,10144103 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04442976 0,10134632 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04442976 0,10125178 ! glycolipid transport GO:0046836 11 7 0,000 0,04442976 0,10115741 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04442976 0,10106322 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,04442976 0,10096921 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04442976 0,10087538 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04442976 0,10078171 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04442976 0,10068822 ! pericardium development GO:0060039 16 7 0,000 0,04442976 0,10059491 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04442976 0,10050176 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04442976 0,10040879 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,04442976 0,10031599 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04442976 0,10022336 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04442976 0,10013091 ! lipoprotein transport GO:0042953 14 7 0,000 0,04442976 0,10003862 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04442976 0,0999465 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04442976 0,09985456 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04442976 0,09976278 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04442976 0,09967117 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04442976 0,09957973 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04442976 0,09948845 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04442976 0,09939735 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04442976 0,09930641 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04442976 0,09921563 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04442976 0,09912503 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04442976 0,09903458 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04442976 0,09894431 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04442976 0,09885419 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04442976 0,09876424 ! spinal cord patterning GO:0021511 14 7 0,000 0,04442976 0,09867446 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04442976 0,09858484 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04442976 0,09849538 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04442976 0,09840608 ! adrenal gland development GO:0030325 17 7 0,000 0,04442976 0,09831694 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04442976 0,09822797 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04442976 0,09813915 ! ovulation GO:0030728 10 7 0,000 0,04442976 0,0980505 ! adenohypophysis development GO:0021984 11 7 0,000 0,04442976 0,09796201 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04442976 0,09787367 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04442976 0,0977855 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04442976 0,09769748 ! microtubule nucleation GO:0007020 21 7 0,000 0,04442976 0,09760963 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04442976 0,09752193 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04442976 0,09743438 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04442976 0,097347 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04442976 0,09725977 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04442976 0,0971727 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04442976 0,09708578 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04442976 0,09699902 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04442976 0,09691241 ! galactose metabolic process GO:0006012 13 7 0,000 0,04442976 0,09682596 ! vesicle fusion GO:0006906 20 7 0,000 0,04442976 0,09673966 ! response to dietary excess GO:0002021 8 7 0,000 0,04442976 0,09665352 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04442976 0,09656753 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04442976 0,09648169 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04442976 0,09639601 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04442976 0,09631047 ! organ growth GO:0035265 15 7 0,000 0,04442976 0,09622509 ! nucleoside transport GO:0015858 11 7 0,000 0,04442976 0,09613986 ! nucleoside salvage GO:0043174 11 7 0,000 0,04442976 0,09605478 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04442976 0,09596985 ! male sex determination GO:0030238 15 7 0,000 0,04442976 0,09588507 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04442976 0,09580044 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04442976 0,09571596 ! parturition GO:0007567 16 7 0,000 0,04442976 0,09563163 ! rRNA modification GO:0000154 14 7 0,000 0,04442976 0,09554745 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04442976 0,09546342 ! spindle checkpoint GO:0031577 16 7 0,000 0,04442976 0,09537953 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04442976 0,09529579 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04442976 0,0952122 ! monocyte differentiation GO:0030224 16 7 0,000 0,04442976 0,09512875 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04442976 0,09504545 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04442976 0,0949623 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04442976 0,09487929 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04442976 0,09479642 ! fibrinolysis GO:0042730 11 7 0,000 0,04442976 0,0947137 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04442976 0,09463113 ! eating behavior GO:0042755 8 7 0,000 0,04442976 0,0945487 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04442976 0,09446641 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04442976 0,09438426 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04442976 0,09430226 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04442976 0,0942204 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04442976 0,09413868 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04442976 0,09405711 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,04442976 0,09397567 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04442976 0,09389438 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04442976 0,09381323 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04442976 0,09373221 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04442976 0,09365134 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04442976 0,09357061 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04442976 0,09349001 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04442976 0,09340956 ! histone ubiquitination GO:0016574 9 7 0,000 0,04442976 0,09332924 ! regulation of meiosis GO:0040020 12 7 0,000 0,04442976 0,09324906 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04442976 0,09316902 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04442976 0,09308911 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04442976 0,09300934 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04442976 0,09292971 ! transcription termination GO:0006353 14 7 0,000 0,04442976 0,09285022 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04442976 0,09277086 ! anaphase GO:0051322 18 7 0,000 0,04442976 0,09269163 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04442976 0,09261255 ! axonal fasciculation GO:0007413 19 7 0,000 0,04442976 0,09253359 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04442976 0,09245477 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04442976 0,09237609 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04442976 0,09229754 ! diuresis GO:0030146 12 7 0,000 0,04442976 0,09221912 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04442976 0,09214084 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04442976 0,09206268 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04442976 0,09198466 ! antibiotic transport GO:0042891 9 7 0,000 0,04442976 0,09190678 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04442976 0,09182902 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04442976 0,0917514 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04442976 0,09167391 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04442976 0,09159654 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04442976 0,09151931 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04442976 0,09144221 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04442976 0,09136524 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04442976 0,0912884 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04442976 0,09121168 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04442976 0,0911351 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04442976 0,09105864 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04442976 0,09098232 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04442976 0,09090612 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04442976 0,09083004 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04442976 0,0907541 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04442976 0,09067828 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04442976 0,09060259 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04442976 0,09052703 ! muscle adaptation GO:0043500 13 7 0,000 0,04442976 0,09045159 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04442976 0,09037627 ! retina homeostasis GO:0001895 12 7 0,000 0,04442976 0,09030108 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04442976 0,09022602 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04442976 0,09015108 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04442976 0,09007627 ! Notch signaling pathway GO:0007219 111 52 1,000 0,04474232 0,09063473 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,04474232 0,09055964 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,04474232 0,09048467 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,04474232 0,09040983 ! histone modification GO:0016570 104 52 1,000 0,04474232 0,09033511 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,04630332 0,09340958 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,04630332 0,09333251 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,04630332 0,09325557 ! synapse organization GO:0050808 102 53 1,000 0,04630332 0,09317875 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,04788412 0,09628057 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,04788412 0,0962014 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,04788412 0,09612235 ! covalent chromatin modification GO:0016569 115 54 1,000 0,04788412 0,09604343 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,04788412 0,09596464 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,0494844 0,09909047 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,0494844 0,09900932 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,05061433 0,10118725 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,05061433 0,10110451 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,05061433 0,10102191 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,05061433 0,10093944 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,05061433 0,10085711 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05061433 0,10077491 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05061433 0,10069285 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,05061433 0,10061091 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,05061433 0,10052912 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,05061433 0,10044745 ! meiotic prophase I GO:0007128 14 8 0,000 0,05061433 0,10036592 ! response to zinc ion GO:0010043 12 8 0,000 0,05061433 0,10028452 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05061433 0,10020325 ! oligopeptide transport GO:0006857 16 8 0,000 0,05061433 0,10012212 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,05061433 0,10004111 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,05061433 0,09996024 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,05061433 0,09987949 ! signal peptide processing GO:0006465 12 8 0,000 0,05061433 0,09979888 ! neurotransmitter uptake GO:0001504 18 8 0,000 0,05061433 0,0997184 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05061433 0,09963805 ! succinate metabolic process GO:0006105 17 8 0,000 0,05061433 0,09955782 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,05061433 0,09947773 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,05061433 0,09939776 ! estrogen metabolic process GO:0008210 17 8 0,000 0,05061433 0,09931792 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,05061433 0,09923821 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05061433 0,09915863 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05061433 0,09907918 ! reflex GO:0060004 17 8 0,000 0,05061433 0,09899985 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05061433 0,09892065 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,05061433 0,09884158 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,05061433 0,09876263 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05061433 0,09868381 ! pigment granule organization GO:0048753 17 8 0,000 0,05061433 0,09860512 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,05061433 0,09852655 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,05061433 0,0984481 ! astrocyte differentiation GO:0048708 19 8 0,000 0,05061433 0,09836978 ! histidine catabolic process GO:0006548 10 8 0,000 0,05061433 0,09829159 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05061433 0,09821351 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,05061433 0,09813557 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,05061433 0,09805774 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,05061433 0,09798004 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,05061433 0,09790247 ! melanin metabolic process GO:0006582 17 8 0,000 0,05061433 0,09782501 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,05061433 0,09774768 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,05061433 0,09767047 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,05061433 0,09759338 ! macrophage activation GO:0042116 13 8 0,000 0,05061433 0,09751642 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05061433 0,09743957 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05061433 0,09736285 ! purine salvage GO:0043101 12 8 0,000 0,05061433 0,09728624 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,05061433 0,09720976 ! osteoblast development GO:0002076 17 8 0,000 0,05061433 0,0971334 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,05061433 0,09705715 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,05061433 0,09698103 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,05061433 0,09690503 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,05061433 0,09682914 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05061433 0,09675338 ! response to UV-B GO:0010224 17 8 0,000 0,05061433 0,09667773 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,05061433 0,0966022 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05061433 0,09652679 ! intermediate filament organization GO:0045109 12 8 0,000 0,05061433 0,09645149 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,05061433 0,09637632 ! cellular extravasation GO:0045123 13 8 0,000 0,05061433 0,09630126 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,05061433 0,09622631 ! response to antibiotic GO:0046677 11 8 0,000 0,05061433 0,09615149 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,05061433 0,09607678 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,05061433 0,09600219 ! response to tropane GO:0014073 15 8 0,000 0,05061433 0,09592771 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,05061433 0,09585334 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,05061433 0,0957791 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05061433 0,09570496 ! mast cell activation GO:0045576 14 8 0,000 0,05061433 0,09563095 ! multicellular organismal aging GO:0010259 20 8 0,000 0,05061433 0,09555704 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,05061433 0,09548325 ! gas homeostasis GO:0033483 14 8 0,000 0,05061433 0,09540958 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,05061433 0,09533602 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,05061433 0,09526257 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,05061433 0,09518923 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05061433 0,09511601 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05061433 0,0950429 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05061433 0,0949699 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,05061433 0,09489702 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,05061433 0,09482424 ! intracellular lipid transport GO:0032365 16 8 0,000 0,05061433 0,09475158 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05061433 0,09467903 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,05061433 0,09460659 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,05061433 0,09453426 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,05061433 0,09446204 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05061433 0,09438993 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,05061433 0,09431794 ! hormone catabolic process GO:0042447 17 8 0,000 0,05061433 0,09424605 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,05061433 0,09417427 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,05061433 0,0941026 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,05061433 0,09403104 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,05061433 0,09395959 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05061433 0,09388824 GO:0010828|positive regulation of glucose transport, ! adult feeding behavior GO:0008343 10 8 0,000 0,05061433 0,09381701 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,05061433 0,09374588 ! ATP catabolic process GO:0006200 11 8 0,000 0,05061433 0,09367486 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05061433 0,09360395 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,05061433 0,09353314 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05061433 0,09346244 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,05061433 0,09339185 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,05061433 0,09332137 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,05061433 0,09325099 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,05061433 0,09318072 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,05061433 0,09311055 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05061433 0,09304049 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,05061433 0,09297054 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,05061433 0,09290069 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05061433 0,09283094 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,05061433 0,0927613 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,05061433 0,09269176 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,05061433 0,09262233 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,05061433 0,092553 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,05061433 0,09248378 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,05110384 0,09330843 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,05274213 0,0962278 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,05439896 0,09917662 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,05439896 0,09910266 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,05439896 0,09902881 ! maintenance of location GO:0051235 124 58 1,000 0,05439896 0,09895508 ! axon extension GO:0048675 16 9 0,000 0,05675905 0,1031714 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05675905 0,10309469 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05675905 0,1030181 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05675905 0,10294162 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05675905 0,10286525 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05675905 0,102789 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05675905 0,10271286 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05675905 0,10263683 ! reproductive behavior GO:0019098 22 9 0,000 0,05675905 0,10256092 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05675905 0,10248512 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05675905 0,10240942 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05675905 0,10233385 ! UTP metabolic process GO:0046051 10 9 0,000 0,05675905 0,10225838 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05675905 0,10218302 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05675905 0,10210778 ! artery development GO:0060840 25 9 0,000 0,05675905 0,10203264 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05675905 0,10195762 ! regulation of glycolysis GO:0006110 20 9 0,000 0,05675905 0,1018827 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05675905 0,1018079 ! equilibrioception GO:0050957 20 9 0,000 0,05675905 0,10173321 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05675905 0,10165862 ! chemosensory behavior GO:0007635 21 9 0,000 0,05675905 0,10158415 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05675905 0,10150978 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05675905 0,10143552 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05675905 0,10136137 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05675905 0,10128733 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05675905 0,1012134 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05675905 0,10113958 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05675905 0,10106586 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05675905 0,10099225 ! protein targeting to ER GO:0045047 25 9 0,000 0,05675905 0,10091875 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05675905 0,10084535 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05675905 0,10077206 ! T cell selection GO:0045058 27 9 0,000 0,05675905 0,10069888 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05675905 0,10062581 ! glycine catabolic process GO:0006546 15 9 0,000 0,05675905 0,10055284 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05675905 0,10047997 ! endosome organization GO:0007032 20 9 0,000 0,05675905 0,10040721 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05675905 0,10033456 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05675905 0,10026201 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05675905 0,10018957 ! mannose metabolic process GO:0006013 13 9 0,000 0,05675905 0,10011723 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05675905 0,10004499 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05675905 0,09997286 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05675905 0,09990084 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05675905 0,09982891 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05675905 0,09975709 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05675905 0,09968538 ! retinol metabolic process GO:0042572 20 9 0,000 0,05675905 0,09961376 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05675905 0,09954225 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05675905 0,09947085 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05675905 0,09939954 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05675905 0,09932834 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05675905 0,09925724 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05675905 0,09918624 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05675905 0,09911534 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05675905 0,09904454 ! response to amine stimulus GO:0014075 13 9 0,000 0,05675905 0,09897385 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05675905 0,09890325 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05675905 0,09883276 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05675905 0,09876237 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05675905 0,09869207 ! renal water homeostasis GO:0003091 15 9 0,000 0,05675905 0,09862188 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05675905 0,09855178 ! icosanoid secretion GO:0032309 15 9 0,000 0,05675905 0,09848179 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05675905 0,0984119 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05675905 0,0983421 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05675905 0,0982724 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05675905 0,09820281 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05675905 0,09813331 ! sterol catabolic process GO:0016127 14 9 0,000 0,05675905 0,0980639 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05675905 0,0979946 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05675905 0,0979254 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05675905 0,09785629 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05675905 0,09778728 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05675905 0,09771837 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05675905 0,09764955 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05675905 0,09758083 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05675905 0,09751221 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05675905 0,09744368 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05675905 0,09737525 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05675905 0,09730692 ! purine base metabolic process GO:0006144 25 9 0,000 0,05675905 0,09723868 ! pigment granule transport GO:0051904 17 9 0,000 0,05675905 0,09717054 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05675905 0,09710249 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05675905 0,09703454 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05675905 0,09696669 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05675905 0,09689892 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05675905 0,09683126 ! mitochondrion localization GO:0051646 18 9 0,000 0,05675905 0,09676369 ! lipid modification GO:0030258 112 60 1,000 0,05776703 0,09841343 ! heterocycle catabolic process GO:0046700 100 60 1,000 0,05776703 0,09834485 ! camera-type eye development GO:0043010 126 61 1,000 0,05947767 0,10118659 ! viral reproductive process GO:0022415 132 62 1,000 0,06120564 0,10405384 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,06286417 0,10679914 ! regulation of developmental growth GO:0048638 16 10 0,000 0,06286417 0,10672493 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,06286417 0,10665081 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06286417 0,1065768 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,06286417 0,10650289 ! associative learning GO:0008306 21 10 0,000 0,06286417 0,10642908 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06286417 0,10635538 ! phosphate transport GO:0006817 24 10 0,000 0,06286417 0,10628178 ! cell volume homeostasis GO:0006884 17 10 0,000 0,06286417 0,10620828 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,06286417 0,10613488 ! CTP metabolic process GO:0046036 11 10 0,000 0,06286417 0,10606158 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,06286417 0,10598838 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06286417 0,10591529 ! GTP metabolic process GO:0046039 11 10 0,000 0,06286417 0,10584229 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,06286417 0,1057694 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,06286417 0,10569661 ! social behavior GO:0035176 29 10 0,000 0,06286417 0,10562391 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,06286417 0,10555132 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,06286417 0,10547882 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,06286417 0,10540643 ! androgen metabolic process GO:0008209 17 10 0,000 0,06286417 0,10533413 ! phospholipid efflux GO:0033700 19 10 0,000 0,06286417 0,10526194 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06286417 0,10518984 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,06286417 0,10511784 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,06286417 0,10504594 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,06286417 0,10497414 ! pathogenesis GO:0009405 17 10 0,000 0,06286417 0,10490244 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,06286417 0,10483083 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,06286417 0,10475932 ! endoderm development GO:0007492 18 10 0,000 0,06286417 0,10468791 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,06286417 0,1046166 ! arginine catabolic process GO:0006527 17 10 0,000 0,06286417 0,10454538 ! proline metabolic process GO:0006560 13 10 0,000 0,06286417 0,10447426 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06286417 0,10440324 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,06286417 0,10433231 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,06286417 0,10426149 ! V(D)J recombination GO:0033151 34 10 0,000 0,06286417 0,10419075 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,06286417 0,10412011 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,06286417 0,10404957 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,06286417 0,10397912 ! B cell proliferation GO:0042100 19 10 0,000 0,06286417 0,10390877 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,06286417 0,10383852 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,06286417 0,10376836 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,06286417 0,10369829 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,06286417 0,10362832 ! ruffle organization GO:0031529 17 10 0,000 0,06286417 0,10355844 ! epithelial cell development GO:0002064 21 10 0,000 0,06286417 0,10348866 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,06286417 0,10341897 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06286417 0,10334937 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,06286417 0,10327987 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,06286417 0,10321046 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,06286417 0,10314115 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,06286417 0,10307192 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,06286417 0,1030028 ! protein heterooligomerization GO:0051291 17 10 0,000 0,06286417 0,10293376 ! brain morphogenesis GO:0048854 23 10 0,000 0,06286417 0,10286481 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,06286417 0,10279596 ! segment specification GO:0007379 15 10 0,000 0,06286417 0,1027272 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,06286417 0,10265853 ! blastoderm segmentation GO:0007350 19 10 0,000 0,06286417 0,10258996 ! response to dsRNA GO:0043331 23 10 0,000 0,06286417 0,10252147 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,06286417 0,10245308 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06286417 0,10238478 ! melanosome localization GO:0032400 16 10 0,000 0,06286417 0,10231657 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,06286417 0,10224845 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,06286417 0,10218042 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,06286417 0,10211248 ! induction of an organ GO:0001759 17 10 0,000 0,06286417 0,10204463 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,06286417 0,10197687 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,06286417 0,1019092 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,06286417 0,10184162 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06286417 0,10177413 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06286417 0,10170673 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06286417 0,10163942 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,06286417 0,1015722 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,06286417 0,10150507 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 14 10 0,000 0,06286417 0,10143802 ! musculoskeletal movement GO:0050881 16 10 0,000 0,06286417 0,10137107 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,06286417 0,1013042 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,06286417 0,10123742 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,06286417 0,10117073 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,06286417 0,10110413 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,06286417 0,10103761 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06286417 0,10097118 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06286417 0,10090484 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,06286417 0,10083859 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,06286417 0,10077242 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06286417 0,10070634 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,06286417 0,10064035 ! cerebellar cortex development GO:0021695 16 10 0,000 0,06286417 0,10057444 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,06286417 0,10050862 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,06286417 0,10044288 ! response to nicotine GO:0035094 20 10 0,000 0,06286417 0,10037723 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,06286417 0,10031167 ! regulation of mitosis GO:0007088 112 63 1,000 0,06295065 0,10038409 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,06295065 0,10031861 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,06649064 0,10589089 GO:0048609|reproductive process in a multicellular organism, ! ear development GO:0043583 114 66 1,000 0,06828504 0,10867775 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06892994 0,10963272 ! respiratory burst GO:0045730 17 11 0,000 0,06892994 0,10956139 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06892994 0,10949015 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,06892994 0,10941901 ! thyroid gland development GO:0030878 26 11 0,000 0,06892994 0,10934796 ! synapsis GO:0007129 14 11 0,000 0,06892994 0,109277 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06892994 0,10920613 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06892994 0,10913536 ! response to pain GO:0048265 27 11 0,000 0,06892994 0,10906467 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06892994 0,10899408 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,06892994 0,10892358 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,06892994 0,10885317 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06892994 0,10878285 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06892994 0,10871262 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06892994 0,10864249 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06892994 0,10857244 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,06892994 0,10850248 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06892994 0,10843262 GO:0010833|telomere maintenance via telomere lengthening, ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06892994 0,10836284 ! UV protection GO:0009650 20 11 0,000 0,06892994 0,10829315 ! adult heart development GO:0007512 16 11 0,000 0,06892994 0,10822356 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06892994 0,10815405 ! macroautophagy GO:0016236 19 11 0,000 0,06892994 0,10808463 ! temperature homeostasis GO:0001659 18 11 0,000 0,06892994 0,1080153 ! behavioral fear response GO:0001662 27 11 0,000 0,06892994 0,10794606 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06892994 0,10787691 ! negative regulation of ossification GO:0030279 27 11 0,000 0,06892994 0,10780785 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06892994 0,10773887 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06892994 0,10766998 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06892994 0,10760119 ! regulation of organ growth GO:0046620 14 11 0,000 0,06892994 0,10753247 ! pigment granule localization GO:0051875 20 11 0,000 0,06892994 0,10746385 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,06892994 0,10739532 ! vasoconstriction GO:0042310 20 11 0,000 0,06892994 0,10732687 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06892994 0,10725851 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06892994 0,10719023 ! embryonic axis specification GO:0000578 19 11 0,000 0,06892994 0,10712205 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06892994 0,10705394 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06892994 0,10698593 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06892994 0,106918 ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06892994 0,10685016 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06892994 0,10678241 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06892994 0,10671474 ! prophase GO:0051324 17 11 0,000 0,06892994 0,10664715 ! nucleosome positioning GO:0016584 15 11 0,000 0,06892994 0,10657966 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06892994 0,10651224 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06892994 0,10644491 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06892994 0,10637767 ! acid secretion GO:0046717 20 11 0,000 0,06892994 0,10631051 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06892994 0,10624344 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06892994 0,10617645 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06892994 0,10610955 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06892994 0,10604273 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,06892994 0,10597599 ! cholesterol efflux GO:0033344 21 11 0,000 0,06892994 0,10590934 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06892994 0,10584278 ! germ cell migration GO:0008354 26 11 0,000 0,06892994 0,10577629 ! embryonic gut development GO:0048566 19 11 0,000 0,06892994 0,10570989 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06892994 0,10564357 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06892994 0,10557734 ! activation of innate immune response GO:0002218 16 11 0,000 0,06892994 0,10551119 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06892994 0,10544512 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06892994 0,10537913 ! lysogeny GO:0030069 22 11 0,000 0,06892994 0,10531323 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06892994 0,10524741 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,06892994 0,10518167 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06892994 0,10511601 ! regulation of embryonic development GO:0045995 35 11 0,000 0,06892994 0,10505044 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,07009534 0,10675992 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,07009534 0,10669341 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,07192126 0,10940451 ! detection of external stimulus GO:0009581 102 68 1,000 0,07192126 0,10933643 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,07192126 0,10926843 ! regulation of lipase activity GO:0060191 137 68 1,000 0,07192126 0,10920052 ! adaptive immune response GO:0002250 126 68 1,000 0,07192126 0,10913269 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07495663 0,11366793 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,07495663 0,11359742 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,07495663 0,11352699 ! virus-host interaction GO:0019048 30 12 0,000 0,07495663 0,11345665 ! mating GO:0007618 17 12 0,000 0,07495663 0,1133864 ! protein complex disassembly GO:0043241 28 12 0,000 0,07495663 0,11331624 GO:0043624|cellular protein complex disassembly, ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07495663 0,11324616 ! T cell proliferation GO:0042098 32 12 0,000 0,07495663 0,11317617 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07495663 0,11310626 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07495663 0,11303644 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07495663 0,11296671 ! drug transport GO:0015893 16 12 0,000 0,07495663 0,11289707 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07495663 0,11282751 ! polyamine metabolic process GO:0006595 18 12 0,000 0,07495663 0,11275803 ! mitotic spindle organization GO:0007052 23 12 0,000 0,07495663 0,11268864 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07495663 0,11261934 ! forebrain cell migration GO:0021885 24 12 0,000 0,07495663 0,11255012 ! lipid digestion GO:0044241 21 12 0,000 0,07495663 0,11248098 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07495663 0,11241193 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07495663 0,11234297 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07495663 0,11227409 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07495663 0,11220529 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07495663 0,11213658 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07495663 0,11206796 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,07495663 0,11199941 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07495663 0,11193095 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07495663 0,11186258 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07495663 0,11179429 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07495663 0,11172608 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07495663 0,11165795 ! cranial nerve development GO:0021545 23 12 0,000 0,07495663 0,11158991 ! fucose catabolic process GO:0019317 25 12 0,000 0,07495663 0,11152195 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,07495663 0,11145407 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,07495663 0,11138628 ! zymogen activation GO:0031638 18 12 0,000 0,07495663 0,11131857 ! T cell homeostasis GO:0043029 28 12 0,000 0,07495663 0,11125094 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07495663 0,11118339 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07495663 0,11111592 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,07495663 0,11104854 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07495663 0,11098124 ! defense response to fungus GO:0050832 15 12 0,000 0,07495663 0,11091402 ! developmental induction GO:0031128 22 12 0,000 0,07495663 0,11084688 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,07495663 0,11077982 ! establishment of cell polarity GO:0030010 21 12 0,000 0,07495663 0,11071284 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07495663 0,11064595 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,07561885 0,11155607 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,07748998 0,11424745 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,07748998 0,11417855 ! appendage morphogenesis GO:0035107 150 72 1,000 0,07937565 0,1168865 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,07937565 0,11681609 ! B cell activation GO:0042113 179 72 1,000 0,07937565 0,11674576 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,07937565 0,11667551 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,08094447 0,11891 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08094447 0,11883854 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,08094447 0,11876717 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,08094447 0,11869588 ! peroxisomal transport GO:0043574 28 13 0,000 0,08094447 0,11862468 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,08094447 0,11855356 ! cartilage condensation GO:0001502 22 13 0,000 0,08094447 0,11848253 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,08094447 0,11841158 ! organelle fusion GO:0048284 36 13 0,000 0,08094447 0,11834072 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,08094447 0,11826994 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,08094447 0,11819925 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,08094447 0,11812864 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,08094447 0,11805811 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,08094447 0,11798767 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,08094447 0,11791731 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,08094447 0,11784704 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,08094447 0,11777685 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08094447 0,11770675 ! methionine metabolic process GO:0006555 31 13 0,000 0,08094447 0,11763673 ! plasma membrane organization GO:0007009 27 13 0,000 0,08094447 0,11756679 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,08094447 0,11749693 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,08094447 0,11742716 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,08094447 0,11735747 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,08094447 0,11728786 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,08094447 0,11721834 ! monoamine transport GO:0015844 21 13 0,000 0,08094447 0,1171489 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,08094447 0,11707954 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,08094447 0,11701026 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,08094447 0,11694106 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,08094447 0,11687195 ! protein homotetramerization GO:0051289 24 13 0,000 0,08094447 0,11680292 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,08094447 0,11673397 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,08094447 0,1166651 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,08094447 0,11659631 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,08094447 0,1165276 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,08094447 0,11645897 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08094447 0,11639043 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,08094447 0,11632196 ! histone methylation GO:0016571 29 13 0,000 0,08094447 0,11625358 ! chromatin silencing GO:0006342 29 13 0,000 0,08094447 0,11618527 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,08094447 0,11611705 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08094447 0,11604891 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,08094447 0,11598084 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,08094447 0,11591286 ! spleen development GO:0048536 24 13 0,000 0,08094447 0,11584495 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,08094447 0,11577713 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,08094447 0,11570938 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,08094447 0,11564172 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,08094447 0,11557413 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08094447 0,11550662 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,08094447 0,11543919 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,08094447 0,11537184 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,08094447 0,11530457 ! insulin secretion GO:0030073 24 13 0,000 0,08094447 0,11523738 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,08094447 0,11517026 ! acrosome reaction GO:0007340 19 13 0,000 0,08094447 0,11510322 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,08094447 0,11503626 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,08094447 0,11496938 ! appendage development GO:0048736 151 73 1,000 0,08127558 0,11537259 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 1,000 0,08127558 0,11530559 ! regulation of immune effector process GO:0002697 156 73 1,000 0,08127558 0,11523867 ! acute inflammatory response GO:0002526 118 74 1,000 0,08318951 0,11788398 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,0851172 0,12054569 ! eye development GO:0001654 155 75 1,000 0,0851172 0,12047585 ! axon guidance GO:0007411 162 75 1,000 0,0851172 0,12040609 ! rhythmic process GO:0048511 142 75 1,000 0,0851172 0,12033641 ! rRNA transcription GO:0009303 28 14 0,000 0,08689372 0,12277695 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08689372 0,12270598 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,08689372 0,1226351 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,08689372 0,12256429 ! non-recombinational repair GO:0000726 29 14 0,000 0,08689372 0,12249357 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,08689372 0,12242293 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08689372 0,12235236 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,08689372 0,12228189 ! RNA polyadenylation GO:0043631 32 14 0,000 0,08689372 0,12221149 ! lipid localization GO:0010876 32 14 0,000 0,08689372 0,12214117 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,08689372 0,12207093 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08689372 0,12200078 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08689372 0,1219307 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08689372 0,12186071 ! arginine metabolic process GO:0006525 21 14 0,000 0,08689372 0,12179079 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08689372 0,12172096 ! regulation of heart rate GO:0002027 25 14 0,000 0,08689372 0,12165121 ! fear response GO:0042596 34 14 0,000 0,08689372 0,12158153 ! organic alcohol transport GO:0015850 29 14 0,000 0,08689372 0,12151194 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,08689372 0,12144242 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,08689372 0,12137299 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08689372 0,12130363 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08689372 0,12123435 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08689372 0,12116516 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,08689372 0,12109604 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08689372 0,121027 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,08689372 0,12095804 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08689372 0,12088915 ! ribosome assembly GO:0042255 18 14 0,000 0,08689372 0,12082035 ! cerebellum development GO:0021549 23 14 0,000 0,08689372 0,12075162 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,08689372 0,12068297 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08689372 0,12061441 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08689372 0,12054591 ! NADP metabolic process GO:0006739 24 14 0,000 0,08689372 0,1204775 ! oxygen transport GO:0015671 22 14 0,000 0,08689372 0,12040916 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08689372 0,1203409 ! male genitalia development GO:0030539 26 14 0,000 0,08689372 0,12027272 ! regulation of axon extension GO:0030516 43 14 0,000 0,08689372 0,12020462 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08689372 0,12013659 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,08689372 0,12006864 ! learning or memory GO:0007611 161 76 1,000 0,08705837 0,12022815 ! regulation of blood pressure GO:0008217 134 76 1,000 0,08705837 0,12016023 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,08705837 0,12009238 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,08901278 0,12271909 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09280462 0,12787462 ! lactation GO:0007595 30 15 0,000 0,09280462 0,12780253 ! reproductive cellular process GO:0048610 22 15 0,000 0,09280462 0,12773053 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09280462 0,12765861 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,09280462 0,12758677 ! superoxide anion generation GO:0042554 22 15 0,000 0,09280462 0,12751501 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,09280462 0,12744334 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,09280462 0,12737174 ! copper ion transport GO:0006825 22 15 0,000 0,09280462 0,12730022 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,09280462 0,12722878 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,09280462 0,12715743 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,09280462 0,12708615 ! sulfate transport GO:0008272 27 15 0,000 0,09280462 0,12701495 ! response to cAMP GO:0051591 25 15 0,000 0,09280462 0,12694384 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,09280462 0,1268728 ! response to hexose stimulus GO:0009746 25 15 0,000 0,09280462 0,12680184 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,09280462 0,12673096 ! vesicle coating GO:0006901 38 15 0,000 0,09280462 0,12666016 ! regulation of exocytosis GO:0017157 26 15 0,000 0,09280462 0,12658944 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,09280462 0,1265188 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,09280462 0,12644824 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,09280462 0,12637776 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,09280462 0,12630735 ! regulation of vasodilation GO:0042312 27 15 0,000 0,09280462 0,12623702 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,09280462 0,12616677 ! histone deacetylation GO:0016575 24 15 0,000 0,09280462 0,1260966 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,09280462 0,12602651 ! water homeostasis GO:0030104 28 15 0,000 0,09280462 0,1259565 ! cofactor transport GO:0051181 30 15 0,000 0,09280462 0,12588656 ! muscle maintenance GO:0046716 26 15 0,000 0,09280462 0,1258167 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,09280462 0,12574692 ! intestinal absorption GO:0050892 31 15 0,000 0,09280462 0,12567721 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,09280462 0,12560759 ! heme biosynthetic process GO:0006783 33 15 0,000 0,09280462 0,12553804 ! cell killing GO:0001906 32 15 0,000 0,09280462 0,12546856 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,09280462 0,12539917 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,09280462 0,12532985 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,09280462 0,1252606 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,09280462 0,12519144 ! actin filament polymerization GO:0030041 27 15 0,000 0,09280462 0,12512235 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,09280462 0,12505333 ! blood coagulation GO:0007596 151 79 1,000 0,09296032 0,12519408 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,09495295 0,12780719 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,09867743 0,13274722 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,09867743 0,13267417 ! positive regulation of cell size GO:0045793 29 16 0,000 0,09867743 0,13260119 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,09867743 0,13252829 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,09867743 0,13245547 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,09867743 0,13238273 ! bone remodeling GO:0046849 28 16 0,000 0,09867743 0,13231008 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,09867743 0,1322375 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09867743 0,132165 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,09867743 0,13209258 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,09867743 0,13202024 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,09867743 0,13194798 ! startle response GO:0001964 28 16 0,000 0,09867743 0,1318758 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,09867743 0,1318037 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,09867743 0,13173167 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,09867743 0,13165973 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,09867743 0,13158786 ! protein polyubiquitination GO:0000209 41 16 0,000 0,09867743 0,13151607 ! glutamate metabolic process GO:0006536 25 16 0,000 0,09867743 0,13144436 ! pituitary gland development GO:0021983 30 16 0,000 0,09867743 0,13137273 ! response to osmotic stress GO:0006970 27 16 0,000 0,09867743 0,13130118 ! lysosomal transport GO:0007041 31 16 0,000 0,09867743 0,1312297 ! fructose metabolic process GO:0006000 25 16 0,000 0,09867743 0,1311583 ! L-amino acid transport GO:0015807 33 16 0,000 0,09867743 0,13108698 ! stem cell development GO:0048864 46 16 0,000 0,09867743 0,13101574 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09867743 0,13094457 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09867743 0,13087348 ! intermediate filament-based process GO:0045103 36 16 0,000 0,09867743 0,13080247 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,09867743 0,13073154 ! negative regulation of immune response GO:0050777 38 16 0,000 0,09867743 0,13066068 ! axon cargo transport GO:0008088 46 16 0,000 0,09867743 0,1305899 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,09867743 0,1305192 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,09867743 0,13044857 ! DNA replication initiation GO:0006270 28 16 0,000 0,09867743 0,13037802 ! neuron recognition GO:0008038 40 16 0,000 0,09867743 0,13030755 ! mRNA splice site selection GO:0006376 44 16 0,000 0,09867743 0,13023715 ! tissue regeneration GO:0042246 27 16 0,000 0,09867743 0,13016682 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,09867743 0,13009658 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,09867743 0,13002641 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,09867743 0,12995631 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,09867743 0,12988629 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09867743 0,12981635 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,09867743 0,12974648 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,09867743 0,12967669 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,09867743 0,12960697 ! peptide hormone processing GO:0016486 27 16 0,000 0,09867743 0,12953732 ! protein import into nucleus GO:0006606 174 82 1,000 0,09897472 0,12985781 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,10100338 0,13244834 ! nuclear import GO:0051170 177 83 1,000 0,10100338 0,13237729 ! T cell activation GO:0042110 189 84 1,000 0,10304358 0,1349788 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,10451238 0,13682945 ! metencephalon development GO:0022037 32 17 0,000 0,10451238 0,13675616 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,10451238 0,13668295 ! endothelial cell migration GO:0043542 31 17 0,000 0,10451238 0,13660982 ! gene silencing by RNA GO:0031047 38 17 0,000 0,10451238 0,13653676 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,10451238 0,13646379 ! glial cell development GO:0021782 28 17 0,000 0,10451238 0,13639089 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,10451238 0,13631807 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,10451238 0,13624533 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,10451238 0,13617267 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,10451238 0,13610008 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,10451238 0,13602757 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,10451238 0,13595514 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,10451238 0,13588278 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,10451238 0,1358105 ! NAD metabolic process GO:0019674 33 17 0,000 0,10451238 0,1357383 ! membrane budding GO:0006900 42 17 0,000 0,10451238 0,13566618 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,10451238 0,13559413 ! regulation of protein binding GO:0043393 33 17 0,000 0,10451238 0,13552216 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,10451238 0,13545026 ! genitalia development GO:0048806 32 17 0,000 0,10451238 0,13537845 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,10451238 0,1353067 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,10451238 0,13523504 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,10451238 0,13516345 ! steroid catabolic process GO:0006706 34 17 0,000 0,10451238 0,13509193 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,10451238 0,13502049 ! gas transport GO:0015669 26 17 0,000 0,10451238 0,13494913 ! organic cation transport GO:0015695 32 17 0,000 0,10451238 0,13487784 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,10451238 0,13480663 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,10451238 0,13473549 ! hemostasis GO:0007599 165 85 1,000 0,10509509 0,13541524 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,10509509 0,13534386 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,10715767 0,13792738 ! regulation of lyase activity GO:0051339 169 86 1,000 0,10715767 0,13785475 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,11030972 0,14183508 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,11030972 0,14176047 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11030972 0,14168594 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,11030972 0,14161148 ! adult walking behavior GO:0007628 36 18 0,000 0,11030972 0,14153711 ! patterning of blood vessels GO:0001569 43 18 0,000 0,11030972 0,14146281 ! heart looping GO:0001947 34 18 0,000 0,11030972 0,14138859 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,11030972 0,14131445 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,11030972 0,14124038 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,11030972 0,1411664 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,11030972 0,14109249 ! glycine metabolic process GO:0006544 30 18 0,000 0,11030972 0,14101866 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11030972 0,1409449 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,11030972 0,14087122 ! DNA integration GO:0015074 32 18 0,000 0,11030972 0,14079762 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,11030972 0,1407241 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,11030972 0,14065065 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,11030972 0,14057728 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,11030972 0,14050399 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,11030972 0,14043077 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,11030972 0,14035763 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,11030972 0,14028457 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,11030972 0,14021158 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,11030972 0,14013867 ! detection of bacterium GO:0016045 22 18 0,000 0,11030972 0,14006583 ! nerve development GO:0021675 34 18 0,000 0,11030972 0,13999307 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,11030972 0,13992038 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,11131514 0,14112241 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,11340959 0,14370312 ! tube morphogenesis GO:0035239 194 89 1,000 0,11340959 0,14362863 ! cellular defense response GO:0006968 123 89 1,000 0,11340959 0,14355421 ! protein localization in nucleus GO:0034504 192 89 1,000 0,11340959 0,14347986 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,11606969 0,14676929 ! negative regulation of defense response GO:0031348 27 19 0,000 0,11606969 0,14669336 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,11606969 0,14661751 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,11606969 0,14654174 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,11606969 0,14646605 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,11606969 0,14639043 ! inositol metabolic process GO:0006020 33 19 0,000 0,11606969 0,14631489 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11606969 0,14623944 ! memory GO:0007613 34 19 0,000 0,11606969 0,14616405 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,11606969 0,14608875 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,11606969 0,14601352 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,11606969 0,14593838 ! cerebral cortex development GO:0021987 40 19 0,000 0,11606969 0,1458633 ! heme metabolic process GO:0042168 40 19 0,000 0,11606969 0,14578831 ! response to fungus GO:0009620 26 19 0,000 0,11606969 0,14571339 ! peptide cross-linking GO:0018149 39 19 0,000 0,11606969 0,14563855 ! protein export from nucleus GO:0006611 40 19 0,000 0,11606969 0,14556379 ! heart process GO:0003015 32 19 0,000 0,11606969 0,1454891 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,11606969 0,14541449 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,11606969 0,14533996 ! visual learning GO:0008542 38 19 0,000 0,11606969 0,1452655 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,11606969 0,14519112 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,11606969 0,14511682 ! vitamin transport GO:0051180 31 19 0,000 0,11606969 0,14504259 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,11606969 0,14496844 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,11606969 0,14489436 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,11606969 0,14482036 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,11606969 0,14474643 ! cilium assembly GO:0042384 38 19 0,000 0,11606969 0,14467258 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,1176288 0,14654113 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 1,000 0,1176288 0,14646644 ! protein secretion GO:0009306 45 20 0,000 0,12179254 0,1515737 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,12179254 0,15149652 ! positive regulation of ossification GO:0045778 50 20 0,000 0,12179254 0,15141942 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,12179254 0,15134241 ! skin development GO:0043588 42 20 0,000 0,12179254 0,15126546 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,12179254 0,1511886 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,12179254 0,15111182 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,12179254 0,15103511 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,12179254 0,15095848 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,12179254 0,15088193 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,12179254 0,15080546 ! bile acid metabolic process GO:0008206 34 20 0,000 0,12179254 0,15072906 ! retinoid metabolic process GO:0001523 34 20 0,000 0,12179254 0,15065274 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,12179254 0,1505765 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,12179254 0,15050034 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,12179254 0,15042425 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,12179254 0,15034824 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,12179254 0,15027231 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,12179254 0,15019645 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,12179254 0,15012067 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,12179254 0,15004497 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,12179254 0,14996934 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,12179254 0,14989379 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,12179254 0,14981831 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,12179254 0,14974291 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,12179254 0,14966759 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,12179254 0,14959234 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,12179254 0,14951717 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,12179254 0,14944207 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,12179254 0,14936705 ! female pregnancy GO:0007565 166 94 1,000 0,12403018 0,15203499 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,12403018 0,15195874 ! regulation of membrane potential GO:0042391 179 94 1,000 0,12403018 0,15188257 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,12618248 0,15444078 ! regulation of cell killing GO:0031341 46 21 0,000 0,12747849 0,1559489 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,12747849 0,15587084 ! cAMP metabolic process GO:0046058 41 21 0,000 0,12747849 0,15579287 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,12747849 0,15571497 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,12747849 0,15563715 ! ovarian follicle development GO:0001541 39 21 0,000 0,12747849 0,15555941 ! smooth muscle contraction GO:0006939 48 21 0,000 0,12747849 0,15548175 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,12747849 0,15540416 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,12747849 0,15532666 ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,12747849 0,15524923 ! sensory perception of pain GO:0019233 33 21 0,000 0,12747849 0,15517187 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,12747849 0,15509459 ! diencephalon development GO:0021536 36 21 0,000 0,12747849 0,15501739 ! collagen fibril organization GO:0030199 62 21 0,000 0,12747849 0,15494027 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,12747849 0,15486323 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,12747849 0,15478626 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,12747849 0,15470936 ! sperm-egg recognition GO:0035036 23 21 0,000 0,12747849 0,15463255 ! actin filament-based movement GO:0030048 47 21 0,000 0,12747849 0,1545558 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,13051359 0,15815709 ! transcription initiation GO:0006352 171 97 1,000 0,13051359 0,15807868 ! forebrain development GO:0030900 210 98 1,000 0,132692 0,16063753 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,132692 0,16055797 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,13312778 0,16100553 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,13312778 0,16092587 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,13312778 0,16084628 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,13312778 0,16076677 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,13312778 0,16068734 ! microtubule-based transport GO:0010970 59 22 0,000 0,13312778 0,16060799 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,13312778 0,16052872 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,13312778 0,16044952 ! vacuolar transport GO:0007034 41 22 0,000 0,13312778 0,1603704 ! central nervous system neuron development GO:0021954 47 22 0,000 0,13312778 0,16029136 ! fucose metabolic process GO:0006004 44 22 0,000 0,13312778 0,1602124 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,13312778 0,16013352 ! stem cell differentiation GO:0048863 57 22 0,000 0,13312778 0,16005471 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,13312778 0,15997598 ! cytolysis GO:0019835 27 22 0,000 0,13312778 0,15989733 ! renal system process GO:0003014 42 22 0,000 0,13312778 0,15981876 ! vasodilation GO:0042311 40 22 0,000 0,13312778 0,15974026 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,13312778 0,15966184 ! G1 phase GO:0051318 44 22 0,000 0,13312778 0,1595835 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,13312778 0,15950524 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,13312778 0,15942705 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,13312778 0,15934894 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,13312778 0,1592709 ! sarcomere organization GO:0045214 32 22 0,000 0,13312778 0,15919294 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,13312778 0,15911506 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,13312778 0,15903725 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,13312778 0,15895952 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,13312778 0,15888186 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,13312778 0,15880429 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,13312778 0,15872678 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,13874066 0,16533826 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,13874066 0,16525765 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,13874066 0,16517711 ! glycerol metabolic process GO:0006071 40 23 0,000 0,13874066 0,16509666 ! viral genome replication GO:0019079 44 23 0,000 0,13874066 0,16501628 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,13874066 0,16493598 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,13874066 0,16485576 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,13874066 0,16477561 ! regeneration GO:0031099 42 23 0,000 0,13874066 0,16469555 ! axis specification GO:0009798 43 23 0,000 0,13874066 0,16461556 ! visual behavior GO:0007632 46 23 0,000 0,13874066 0,16453565 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,13874066 0,16445581 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,13874066 0,16437606 ! response to ethanol GO:0045471 47 23 0,000 0,13874066 0,16429638 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,13874066 0,16421678 ! peroxisome organization GO:0007031 43 23 0,000 0,13874066 0,16413726 ! lysosome organization GO:0007040 47 23 0,000 0,13874066 0,16405781 ! vesicle targeting GO:0006903 49 23 0,000 0,13874066 0,16397844 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,13874066 0,16389915 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,13874066 0,16381993 ! fatty acid transport GO:0015908 47 23 0,000 0,13874066 0,16374079 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,13874066 0,16366173 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,13874066 0,16358274 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,13874066 0,16350383 ! cell-cell recognition GO:0009988 28 23 0,000 0,13874066 0,16342499 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,13874066 0,16334623 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,13874066 0,16326755 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,14431735 0,16974833 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,14431735 0,16966665 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,14431735 0,16958504 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,14431735 0,16950351 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,14431735 0,16942205 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,14431735 0,16934068 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,14431735 0,16925938 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,14431735 0,16917816 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,14431735 0,16909702 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,14431735 0,16901596 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,14431735 0,16893497 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,14431735 0,16885407 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,14431735 0,16877324 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,14431735 0,16869248 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,14431735 0,16861181 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,14431735 0,16853121 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,14431735 0,16845069 ! membrane depolarization GO:0051899 45 24 0,000 0,14431735 0,16837024 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,14431735 0,16828988 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,14431735 0,16820959 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,14431735 0,16812937 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,14431735 0,16804923 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,14431735 0,16796917 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,14431735 0,16788919 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,14431735 0,16780928 ! regulation of amine transport GO:0051952 41 24 0,000 0,14431735 0,16772944 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,14985809 0,17408622 ! leukocyte adhesion GO:0007159 55 25 0,000 0,14985809 0,17400348 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,14985809 0,17392081 ! phototransduction GO:0007602 37 25 0,000 0,14985809 0,17383823 ! keratinization GO:0031424 37 25 0,000 0,14985809 0,17375573 ! vacuole organization GO:0007033 49 25 0,000 0,14985809 0,1736733 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,14985809 0,17359095 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,14985809 0,17350868 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,14985809 0,17342649 ! immunoglobulin production GO:0002377 62 25 0,000 0,14985809 0,17334437 GO:0002440|production of molecular mediator of immune response, ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,14985809 0,17326233 ! liver development GO:0001889 55 25 0,000 0,14985809 0,17318038 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,15536311 0,17945724 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,15536311 0,17937243 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,15536311 0,1792877 GO:0006479|protein amino acid methylation, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,15536311 0,17920305 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,15536311 0,17911848 ! digestive system process GO:0022600 49 26 0,000 0,15536311 0,17903399 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,15536311 0,17894958 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,15536311 0,17886525 ! osteoblast differentiation GO:0001649 63 26 0,000 0,15536311 0,178781 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,15536311 0,17869683 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,15536311 0,17861274 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,15536311 0,17852872 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! response to estradiol stimulus GO:0032355 43 26 0,000 0,15536311 0,17844479 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,15536311 0,17836093 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,15536311 0,17827716 ! telomere organization GO:0032200 46 26 0,000 0,15536311 0,17819346 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,15536311 0,17810984 ! neural tube closure GO:0001843 58 26 0,000 0,15536311 0,1780263 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,15536311 0,17794283 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,15536311 0,17785945 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,15536311 0,17777614 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,16083263 0,18394855 ! embryonic pattern specification GO:0009880 49 27 0,000 0,16083263 0,18386247 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,16083263 0,18377648 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,16083263 0,18369056 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,16083263 0,18360472 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,16083263 0,18351897 ! iron ion transport GO:0006826 65 27 0,000 0,16083263 0,18343329 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,16083263 0,18334769 ! superoxide metabolic process GO:0006801 41 27 0,000 0,16083263 0,18326218 ! tube lumen formation GO:0035148 59 27 0,000 0,16083263 0,18317674 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,16083263 0,18309138 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,16083263 0,18300611 ! leukocyte proliferation GO:0070661 59 27 0,000 0,16083263 0,18292091 GO:0032943|mononuclear cell proliferation, ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,16626688 0,18901349 ! vesicle docking GO:0048278 55 28 0,000 0,16626688 0,18892558 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,16626688 0,18883775 ! sperm motility GO:0030317 37 28 0,000 0,16626688 0,18875 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,16626688 0,18866233 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,16626688 0,18857474 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,16626688 0,18848724 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,16626688 0,18839981 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,16626688 0,18831247 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,16626688 0,18822521 ! glutathione metabolic process GO:0006749 42 28 0,000 0,16626688 0,18813803 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,16626688 0,18805092 ! lipid oxidation GO:0034440 48 28 0,000 0,16626688 0,1879639 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,16626688 0,18787696 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,16626688 0,18779011 ! translational initiation GO:0006413 66 29 0,000 0,1716661 0,19379865 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,1716661 0,19370914 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,1716661 0,19361971 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,1716661 0,19353036 ! primary neural tube formation GO:0014020 61 29 0,000 0,1716661 0,19344109 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,1716661 0,19335191 ! synaptogenesis GO:0007416 46 29 0,000 0,1716661 0,1932628 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,1716661 0,19317378 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,1716661 0,19308485 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,1716661 0,19299599 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,17703051 0,19893538 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,17703051 0,19884392 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,17703051 0,19875254 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,17703051 0,19866124 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,17703051 0,19857003 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,17703051 0,1984789 ! myofibril assembly GO:0030239 50 30 0,000 0,17703051 0,19838786 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,17703051 0,19829689 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,17703051 0,19820602 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,17703051 0,19811522 ! cell fate determination GO:0001709 64 30 0,000 0,17703051 0,19802451 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,17703051 0,19793388 ! phospholipid transport GO:0015914 65 30 0,000 0,17703051 0,19784333 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,17703051 0,19775287 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,17703051 0,19766249 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,17703051 0,19757219 ! regulation of coagulation GO:0050818 52 30 0,000 0,17703051 0,19748197 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,18236032 0,20333467 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,18236032 0,20324191 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,18236032 0,20314923 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,18236032 0,20305664 ! regulation of innate immune response GO:0045088 57 31 0,000 0,18236032 0,20296413 ! ovulation cycle process GO:0022602 55 31 0,000 0,18236032 0,2028717 ! detection of light stimulus GO:0009583 44 31 0,000 0,18236032 0,20277936 ! natural killer cell activation GO:0030101 50 31 0,000 0,18236032 0,20268711 ! cofactor catabolic process GO:0051187 54 31 0,000 0,18236032 0,20259493 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,18236032 0,20250284 ! eye morphogenesis GO:0048592 65 31 0,000 0,18236032 0,20241084 ! response to heat GO:0009408 54 31 0,000 0,18236032 0,20231892 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,18236032 0,20222708 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,18765576 0,208005 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,18765576 0,20791067 ! muscle cell development GO:0055001 52 32 0,000 0,18765576 0,20781642 ! mesoderm formation GO:0001707 73 32 0,000 0,18765576 0,20772226 ! ovulation cycle GO:0042698 57 32 0,000 0,18765576 0,20762818 ! BMP signaling pathway GO:0030509 71 32 0,000 0,18765576 0,20753419 ! hindbrain development GO:0030902 65 32 0,000 0,18765576 0,20744028 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,18765576 0,20734646 ! gene silencing GO:0016458 71 32 0,000 0,18765576 0,20725273 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,19291706 0,21296718 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,19291706 0,21287099 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,19291706 0,21277489 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,19291706 0,21267887 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,19291706 0,21258294 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,19291706 0,2124871 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,19291706 0,21239134 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,19291706 0,21229567 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,19291706 0,21220008 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,19814443 0,21785186 ! post-embryonic development GO:0009791 76 34 0,000 0,19814443 0,21775386 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,19814443 0,21765595 ! cholesterol transport GO:0030301 62 34 0,000 0,19814443 0,21755813 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,19814443 0,21746039 ! spliceosome assembly GO:0000245 75 34 0,000 0,19814443 0,21736275 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,19814443 0,21726519 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,19814443 0,21716772 ! formation of primary germ layer GO:0001704 76 34 0,000 0,19814443 0,21707033 ! adult locomotory behavior GO:0008344 62 34 0,000 0,19814443 0,21697303 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,20333809 0,22256046 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,20333809 0,22246079 ! membrane docking GO:0022406 69 35 0,000 0,20333809 0,22236121 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,20333809 0,22226172 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,20333809 0,22216232 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,20333809 0,22206301 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,20333809 0,22196378 ! ceramide metabolic process GO:0006672 72 35 0,000 0,20333809 0,22186465 ! sterol transport GO:0015918 63 35 0,000 0,20333809 0,2217656 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,20333809 0,22166664 ! vesicle localization GO:0051648 70 35 0,000 0,20333809 0,22156777 ! regulation of muscle development GO:0048634 82 36 0,000 0,20849825 0,22708927 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,20849825 0,22698807 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,20849825 0,22688696 ! positive regulation of cell development GO:0010720 85 36 0,000 0,20849825 0,22678594 ! protein targeting to membrane GO:0006612 75 36 0,000 0,20849825 0,22668501 ! aerobic respiration GO:0009060 56 36 0,000 0,20849825 0,22658417 ! cytokine production GO:0001816 68 36 0,000 0,20849825 0,22648343 ! embryonic organ development GO:0048568 67 36 0,000 0,20849825 0,22638277 ! odontogenesis GO:0042476 74 37 0,000 0,21362513 0,23184638 ! actomyosin structure organization GO:0031032 68 37 0,000 0,21362513 0,23174343 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,21362513 0,23164057 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,21871895 0,23705874 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,21871895 0,23695361 ! organic anion transport GO:0015711 82 38 0,000 0,21871895 0,23684858 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,21871895 0,23674364 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,21871895 0,2366388 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,21871895 0,23653404 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,21871895 0,23642938 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,21871895 0,23632481 ! spermatid development GO:0007286 69 38 0,000 0,21871895 0,23622034 ! pigment metabolic process GO:0042440 87 38 0,000 0,21871895 0,23611595 ! neural tube formation GO:0001841 79 38 0,000 0,21871895 0,23601166 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,22377992 0,24136615 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,22377992 0,24125964 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,22377992 0,24115322 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,22377992 0,24104689 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,22377992 0,24094065 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,22880824 0,24624605 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,22880824 0,24613762 ! lipid homeostasis GO:0055088 75 40 0,000 0,22880824 0,24602928 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,22880824 0,24592104 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,22880824 0,2458129 ! RNA export from nucleus GO:0006405 61 41 0,000 0,23380413 0,25106967 ! mRNA catabolic process GO:0006402 79 41 0,000 0,23380413 0,25095936 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,23380413 0,25084914 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,23380413 0,25073902 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,23380413 0,250629 ! feeding behavior GO:0007631 69 41 0,000 0,23380413 0,25051908 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,23380413 0,25040925 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,23380413 0,25029952 ! RNA modification GO:0009451 64 41 0,000 0,23380413 0,25018988 ! organic ether metabolic process GO:0018904 59 42 0,000 0,2387678 0,25538955 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,2387678 0,25527778 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,2387678 0,25516611 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,2387678 0,25505454 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,24369945 0,26020881 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,24369945 0,26009513 ! regulation of tube size GO:0035150 76 43 0,000 0,24369945 0,25998155 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,24369945 0,25986807 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,24369945 0,25975469 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,24369945 0,25964141 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,24369945 0,25952823 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,24369945 0,25941514 ! ion transmembrane transport GO:0034220 79 43 0,000 0,24369945 0,25930216 ! neuron migration GO:0001764 85 43 0,000 0,24369945 0,25918927 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,24369945 0,25907648 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,24859928 0,26417053 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,24859928 0,26405568 ! striated muscle contraction GO:0006941 85 44 0,000 0,24859928 0,26394092 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,24859928 0,26382626 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,25346751 0,26887587 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,25346751 0,26875917 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,25346751 0,26864258 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,25346751 0,26852608 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,25346751 0,26840968 ! polyol metabolic process GO:0019751 77 45 0,000 0,25346751 0,26829339 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,25830434 0,27329472 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,25830434 0,27317641 ! glycolysis GO:0006096 71 46 0,000 0,25830434 0,2730582 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,25830434 0,2729401 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,25830434 0,27282209 ! cell growth GO:0016049 90 46 0,000 0,25830434 0,27270419 ! neural tube development GO:0021915 91 47 0,000 0,26310996 0,27765773 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,26310996 0,27753784 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,26788458 0,28245233 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,26788458 0,28233047 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,26788458 0,28220873 ! response to calcium ion GO:0051592 94 49 0,000 0,2726284 0,28708241 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,2726284 0,28695872 ! JNK cascade GO:0007254 106 49 0,000 0,2726284 0,28683514 ! regulation of ion transport GO:0043269 86 50 0,000 0,27734161 0,29166834 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,27734161 0,29154284 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,27734161 0,29141745 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,27734161 0,29129216 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,27734161 0,29116698 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,28202442 0,29595604 ! peptide metabolic process GO:0006518 80 51 0,000 0,28202442 0,29582896 ! excretion GO:0007588 87 52 0,000 0,28667701 0,30058023 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,28667701 0,30045128 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,28667701 0,30032244 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,28667701 0,30019371 ! amino acid activation GO:0043038 98 52 0,000 0,28667701 0,30006509 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,29129958 0,30477296 ! positive regulation of growth GO:0045927 96 53 0,000 0,29129958 0,3046425 ! inner ear development GO:0048839 89 53 0,000 0,29129958 0,30451214 ! chromatin remodeling GO:0006338 122 53 0,000 0,29129958 0,30438189 ! vesicle organization GO:0016050 127 53 0,000 0,29129958 0,30425176 ! regulation of translational initiation GO:0006446 87 54 0,000 0,29589232 0,30891664 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,29589232 0,30878468 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,29589232 0,30865284 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,29589232 0,3085211 ! RNA catabolic process GO:0006401 103 55 0,000 0,30045543 0,31314532 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,30045543 0,31301178 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,30045543 0,31287836 ! cell recognition GO:0008037 98 55 0,000 0,30045543 0,31274505 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,30045543 0,31261185 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,30045543 0,31247877 ! glucose catabolic process GO:0006007 88 56 0,000 0,3049891 0,31705888 ! RNA elongation GO:0006354 90 56 0,000 0,3049891 0,31692402 ! chloride transport GO:0006821 102 57 0,000 0,30949351 0,32146796 ! heart morphogenesis GO:0003007 105 57 0,000 0,30949351 0,32133134 ! regulation of actin filament length GO:0030832 118 58 0,000 0,31396885 0,32583938 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,31396885 0,32570102 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,31396885 0,32556278 ! gastrulation GO:0007369 122 58 0,000 0,31396885 0,32542465 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,31396885 0,32528664 ! nuclear export GO:0051168 110 59 0,000 0,31841531 0,32975354 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,32283308 0,33418696 ! regulation of endocytosis GO:0030100 104 60 0,000 0,32283308 0,33404541 ! adult behavior GO:0030534 104 60 0,000 0,32283308 0,33390399 ! regulation of cellular component size GO:0032535 125 61 0,000 0,32722234 0,33830054 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,32722234 0,33815743 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,32722234 0,33801445 ! proton transport GO:0015992 117 61 0,000 0,32722234 0,33787159 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,33158327 0,34222979 ! tRNA processing GO:0008033 102 62 0,000 0,33158327 0,34208527 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,33591605 0,346409 ! hydrogen transport GO:0006818 121 64 0,000 0,34022087 0,35070025 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,34022087 0,35055234 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,34022087 0,35040455 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,34449791 0,35466009 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,34449791 0,35451069 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,34449791 0,35436143 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,34449791 0,35421228 ! activation of MAPK activity GO:0000187 124 67 0,000 0,35296933 0,36276991 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,35296933 0,36261736 ! secondary metabolic process GO:0019748 125 67 0,000 0,35296933 0,36246494 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,35716408 0,36661843 ! hexose catabolic process GO:0019320 113 68 0,000 0,35716408 0,36646445 ! extracellular matrix organization GO:0030198 146 68 0,000 0,35716408 0,3663106 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,35716408 0,36615688 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,35716408 0,36600329 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,36133175 0,37011886 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,36133175 0,36996373 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,36133175 0,36980874 ! single fertilization GO:0007338 83 69 0,000 0,36133175 0,36965388 ! cell redox homeostasis GO:0045454 114 70 0,000 0,36547252 0,37373351 ! activation of immune response GO:0002253 120 70 0,000 0,36547252 0,37357714 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,36958655 0,37762441 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,37367403 0,38164116 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,37367403 0,38148168 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,37367403 0,38132233 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,37367403 0,38116312 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,37773512 0,38514478 ! amino acid transport GO:0006865 148 74 0,000 0,38176999 0,38909641 ! transition metal ion transport GO:0000041 143 75 0,000 0,38577882 0,3930182 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,38976175 0,39691037 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,38976175 0,39674499 ! amine catabolic process GO:0009310 136 77 0,000 0,39371898 0,40060619 ! neurotransmitter transport GO:0006836 142 77 0,000 0,39371898 0,40043941 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,39371898 0,40027277 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,39371898 0,40010627 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,39371898 0,3999399 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,39371898 0,39977368 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,39765065 0,40359806 ! antigen processing and presentation GO:0019882 117 78 0,000 0,39765065 0,40343046 ! fertilization GO:0009566 99 78 0,000 0,39765065 0,40326299 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,40155694 0,40705543 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,40155694 0,4068866 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,40155694 0,40671791 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,409294 0,41438261 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,41693147 0,42194017 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,41693147 0,42176545 ! inorganic anion transport GO:0015698 156 83 0,000 0,41693147 0,42159088 ! response to metal ion GO:0010038 158 84 0,000 0,42071325 0,42523892 ! digestion GO:0007586 130 84 0,000 0,42071325 0,42506305 ! regulation of ligase activity GO:0051340 147 84 0,000 0,42071325 0,42488734 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,42447061 0,42850483 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,43191268 0,43583754 ! alcohol catabolic process GO:0046164 142 87 0,000 0,43191268 0,43565759 ! nucleosome assembly GO:0006334 126 87 0,000 0,43191268 0,43547779 ! cellular respiration GO:0045333 143 88 0,000 0,43559771 0,43901205 ! sensory perception of smell GO:0007608 117 88 0,000 0,43559771 0,43883102 ! chromatin assembly GO:0031497 128 88 0,000 0,43559771 0,43865013 ! response to inorganic substance GO:0010035 173 90 0,000 0,44289652 0,44581632 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,44289652 0,44563271 ! response to unfolded protein GO:0006986 139 90 0,000 0,44289652 0,44544924 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,45010135 0,4525093 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,4536689 0,45590832 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,4536689 0,45572086 ! vitamin metabolic process GO:0006766 153 93 0,000 0,4536689 0,45553355 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,4572134 0,458904 ! sterol metabolic process GO:0016125 166 94 0,000 0,4572134 0,45871554 ! nucleosome organization GO:0034728 143 95 0,000 0,46073501 0,46205896 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,46073501 0,46186936 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,46073501 0,46167991 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,46073501 0,46149062 ! response to protein stimulus GO:0051789 158 96 0,000 0,46423386 0,46480464 ! mRNA transport GO:0051028 185 100 0,000 0,4780047 0,47839635 ! positive regulation of immune response GO:0050778 175 100 0,000 0,4780047 0,47820045 ! hormone metabolic process GO:0042445 171 100 0,000 0,4780047 0,4780047