pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6934-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 6 6 4,000 1,578E-10 3,63E-07 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 4,000 1,455E-09 1,673E-06 ! cell cycle checkpoint GO:0000075 108 64 8,000 1,532E-09 1,175E-06 ! negative regulation of peptide secretion GO:0002792 6 5 3,000 1,742E-08 1,001E-05 GO:0046676|negative regulation of insulin secretion, ! cellular response to hormone stimulus GO:0032870 109 74 7,000 1,067E-07 4,91E-05 ! organ growth GO:0035265 11 7 3,000 1,204E-07 4,617E-05 ! regulation of growth hormone secretion GO:0060123 11 7 3,000 1,204E-07 3,957E-05 ! DNA damage checkpoint GO:0000077 53 31 5,000 1,245E-07 3,579E-05 ! DNA integrity checkpoint GO:0031570 57 34 5,000 2,231E-07 5,701E-05 ! DNA damage response, signal transduction GO:0042770 96 56 6,000 2,492E-07 5,732E-05 ! regulation of intracellular protein transport GO:0033157 59 35 5,000 2,675E-07 5,594E-05 ! positive regulation of MAP kinase activity GO:0043406 121 85 7,000 3,172E-07 6,08E-05 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 5,000 8,269E-07 1,463E-04 ! protein amino acid autophosphorylation GO:0046777 80 45 5,000 1,26E-06 2,069E-04 ! regulation of intracellular transport GO:0032386 78 49 5,000 2,108E-06 3,232E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 2,681E-06 3,853E-04 ! negative regulation of hormone secretion GO:0046888 20 15 3,000 4,475E-06 6,055E-04 ! cranial nerve morphogenesis GO:0021602 6 5 2,000 4,553E-06 5,818E-04 ! carbohydrate homeostasis GO:0033500 39 33 4,000 5,272E-06 6,382E-04 GO:0042593|glucose homeostasis, ! activation of MAPK activity GO:0000187 84 59 5,000 6,373E-06 7,329E-04 ! positive regulation of hormone secretion GO:0046887 24 17 3,000 7,709E-06 8,444E-04 ! peptidyl-amino acid modification GO:0018193 147 93 6,000 8,018E-06 8,383E-04 ! hormone-mediated signaling GO:0009755 49 36 4,000 8,219E-06 8,219E-04 ! N-terminal protein amino acid acetylation GO:0006474 7 6 2,000 9,054E-06 8,677E-04 ! ER overload response GO:0006983 7 6 2,000 9,054E-06 8,33E-04 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 9,852E-06 8,716E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 1,399E-05 1,192E-03 ! G1 DNA damage checkpoint GO:0031571 18 7 2,000 1,575E-05 1,294E-03 ! regulation of insulin secretion GO:0050796 26 21 3,000 1,892E-05 1,501E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 3,000 1,892E-05 1,451E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 3,000 2,299E-05 1,706E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 2,506E-05 1,801E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 2,506E-05 1,747E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,506E-05 1,695E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 3,000 2,766E-05 1,818E-03 ! regulation of protein transport GO:0051223 114 76 5,000 2,775E-05 1,773E-03 GO:0070201|regulation of establishment of protein localization, ! response to UV GO:0009411 75 46 4,000 2,808E-05 1,745E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 3,3E-05 1,997E-03 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 3,000 3,3E-05 1,946E-03 ! regulation of DNA replication GO:0006275 75 48 4,000 3,464E-05 1,992E-03 ! regulation of peptide secretion GO:0002791 34 25 3,000 3,904E-05 2,19E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 3,000 4,586E-05 2,512E-03 ! regulation of protein localization GO:0032880 132 85 5,000 5,244E-05 2,805E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 5,31E-05 2,776E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 2,000 5,31E-05 2,714E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 2,000 5,31E-05 2,655E-03 ! cranial nerve development GO:0021545 12 10 2,000 5,31E-05 2,598E-03 ! triglyceride metabolic process GO:0006641 34 28 3,000 6,206E-05 2,974E-03 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 3,000 6,206E-05 2,913E-03 ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 7,259E-05 3,339E-03 GO:0042130|negative regulation of T cell proliferation, ! multicellular organism reproduction GO:0032504 83 57 4,000 8,009E-05 3,612E-03 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of secretion GO:0051048 49 31 3,000 9,366E-05 4,143E-03 ! mammary gland development GO:0030879 57 31 3,000 9,366E-05 4,065E-03 ! lung development GO:0030324 94 59 4,000 9,458E-05 4,028E-03 ! histone acetylation GO:0016573 23 12 2,000 9,624E-05 4,025E-03 ! autonomic nervous system development GO:0048483 23 12 2,000 9,624E-05 3,953E-03 ! peptidyl-lysine modification GO:0018205 18 12 2,000 9,624E-05 3,883E-03 ! neutral lipid metabolic process GO:0006638 41 32 3,000 1,064E-04 4,219E-03 GO:0006639|acylglycerol metabolic process, ! negative regulation of cell growth GO:0030308 106 62 4,000 1,2E-04 4,678E-03 ! respiratory tube development GO:0030323 99 62 4,000 1,2E-04 4,6E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 2,000 1,244E-04 4,691E-03 ! mRNA catabolic process GO:0006402 48 34 3,000 1,356E-04 5,03E-03 ! mitotic cell cycle checkpoint GO:0007093 63 34 3,000 1,356E-04 4,95E-03 ! glycerol ether metabolic process GO:0006662 44 34 3,000 1,356E-04 4,872E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 1,356E-04 4,797E-03 ! negative regulation of cell size GO:0045792 108 64 4,000 1,396E-04 4,866E-03 ! respiratory system development GO:0060541 100 64 4,000 1,396E-04 4,793E-03 ! phosphoinositide phosphorylation GO:0046854 21 14 2,000 1,574E-04 5,325E-03 ! cellular response to starvation GO:0009267 21 14 2,000 1,574E-04 5,248E-03 ! G1/S transition checkpoint GO:0031575 33 14 2,000 1,574E-04 5,173E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,574E-04 5,1E-03 ! regulation of hormone secretion GO:0046883 48 36 3,000 1,701E-04 5,435E-03 ! organic ether metabolic process GO:0018904 46 36 3,000 1,701E-04 5,361E-03 ! lipid phosphorylation GO:0046834 23 15 2,000 1,957E-04 6,082E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 2,000 1,957E-04 6E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 1,957E-04 5,922E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 1,957E-04 5,845E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! protein amino acid acetylation GO:0006473 28 16 2,000 2,395E-04 7,061E-03 ! nerve development GO:0021675 18 16 2,000 2,395E-04 6,971E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 2,891E-04 8,312E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 2,891E-04 8,209E-03 ! peptidyl-serine modification GO:0018209 27 17 2,000 2,891E-04 8,109E-03 ! negative regulation of growth GO:0045926 123 75 4,000 2,952E-04 8,181E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 3,418E-04 9,358E-03 ! response to insulin stimulus GO:0032868 63 43 3,000 3,418E-04 9,248E-03 ! epithelial tube morphogenesis GO:0060562 65 43 3,000 3,418E-04 9,14E-03 ! positive regulation of DNA replication GO:0045740 29 18 2,000 3,45E-04 9,12E-03 ! cellular response to nutrient levels GO:0031669 27 18 2,000 3,45E-04 9,016E-03 ! gut development GO:0048565 26 18 2,000 3,45E-04 8,915E-03 ! negative regulation of T cell activation GO:0050868 25 18 2,000 3,45E-04 8,816E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 3,737E-04 9,445E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 4,073E-04 0,01018299 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 4,073E-04 0,01007349 ! cellular response to reactive oxygen species GO:0034614 27 19 2,000 4,073E-04 9,966E-03 ! response to starvation GO:0042594 30 19 2,000 4,073E-04 9,861E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 4,073E-04 9,759E-03 ! positive regulation of cell cycle GO:0045787 77 45 3,000 4,077E-04 9,667E-03 ! RNA catabolic process GO:0006401 64 45 3,000 4,077E-04 9,568E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 4,765E-04 0,01106973 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 4,822E-04 0,01109128 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of DNA metabolic process GO:0051052 135 85 4,000 5,273E-04 0,01200839 ! anterior/posterior pattern formation GO:0009952 124 85 4,000 5,273E-04 0,01189066 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 5,527E-04 0,01234271 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 5,527E-04 0,01222403 ! protein amino acid acylation GO:0043543 37 21 2,000 5,527E-04 0,01210761 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 5,527E-04 0,01199339 ! cell cycle arrest GO:0007050 150 86 4,000 5,564E-04 0,01196039 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 5,564E-04 0,01184965 ! sleep GO:0030431 11 5 1,000 5,916E-04 0,01248375 ! forebrain regionalization GO:0021871 6 5 1,000 5,916E-04 0,01237026 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 5,916E-04 0,01225882 ! rhythmic behavior GO:0007622 12 5 1,000 5,916E-04 0,01214936 ! positive regulation of glycolysis GO:0045821 11 5 1,000 5,916E-04 0,01204185 ! endochondral ossification GO:0001958 12 5 1,000 5,916E-04 0,01193622 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 5,916E-04 0,01183242 ! microvillus organization GO:0032528 7 5 1,000 5,916E-04 0,01173042 GO:0030033|microvillus assembly, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 1,000 5,916E-04 0,01163016 ! enteric nervous system development GO:0048484 8 5 1,000 5,916E-04 0,0115316 ! regulation of respiratory burst GO:0060263 8 5 1,000 5,916E-04 0,01143469 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 5,916E-04 0,01133941 GO:0007439|ectodermal gut development, ! regulation of multicellular organism growth GO:0040014 65 50 3,000 6,115E-04 0,01162411 ! interphase GO:0051325 159 88 4,000 6,182E-04 0,01165467 ! protein import into nucleus, translocation GO:0000060 36 22 2,000 6,364E-04 0,01189985 ! spliceosomal snRNP biogenesis GO:0000387 28 22 2,000 6,364E-04 0,01180389 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 2,000 6,364E-04 0,01170946 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 2,000 6,364E-04 0,01161652 ! ureteric bud development GO:0001657 32 22 2,000 6,364E-04 0,01152506 ! protein tetramerization GO:0051262 39 22 2,000 6,364E-04 0,01143502 ! positive regulation of secretion GO:0051047 71 51 3,000 6,596E-04 0,01176039 ! positive regulation of cell migration GO:0030335 92 51 3,000 6,596E-04 0,01166993 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 7,277E-04 0,01277627 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 7,277E-04 0,01267948 ! cellular response to oxidative stress GO:0034599 33 23 2,000 7,277E-04 0,01258414 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 7,277E-04 0,01249023 ! skeletal system morphogenesis GO:0048705 78 53 3,000 7,637E-04 0,01301097 ! regulation of helicase activity GO:0051095 11 6 1,000 8,829E-04 0,01493148 ! male meiosis GO:0007140 7 6 1,000 8,829E-04 0,01482249 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 1,000 8,829E-04 0,01471508 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 1,000 8,829E-04 0,01460921 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 1,000 8,829E-04 0,01450486 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 8,829E-04 0,01440199 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 8,829E-04 0,01430057 ! maintenance of protein location in nucleus GO:0051457 16 6 1,000 8,829E-04 0,01420056 ! male sex determination GO:0030238 9 6 1,000 8,829E-04 0,01410195 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 1,000 8,829E-04 0,01400469 ! DNA topological change GO:0006265 8 6 1,000 8,829E-04 0,01390877 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 8,829E-04 0,01381415 ! negative regulation of B cell activation GO:0050869 9 6 1,000 8,829E-04 0,01372081 ! response to light stimulus GO:0009416 153 96 4,000 9,18E-04 0,01416992 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 9,344E-04 0,01432706 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 39 25 2,000 9,344E-04 0,01423218 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 9,344E-04 0,01413855 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 9,344E-04 0,01404614 ! positive regulation of cell motion GO:0051272 99 56 3,000 9,408E-04 0,01405119 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,006E-03 0,01492447 ! response to peptide hormone stimulus GO:0043434 84 57 3,000 1,006E-03 0,0148288 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,074E-03 0,01573126 ! Ras protein signal transduction GO:0007265 162 100 4,000 1,103E-03 0,0160571 ! response to ionizing radiation GO:0010212 47 27 2,000 1,175E-03 0,01699482 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 1,175E-03 0,01688861 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,23E-03 0,01756807 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 1,23E-03 0,01745962 ! microtubule bundle formation GO:0001578 8 7 1,000 1,23E-03 0,01735251 ! spinal cord patterning GO:0021511 7 7 1,000 1,23E-03 0,0172467 ! protein heterooligomerization GO:0051291 10 7 1,000 1,23E-03 0,01714217 ! B cell lineage commitment GO:0002326 17 7 1,000 1,23E-03 0,01703891 ! spinal cord motor neuron differentiation GO:0021522 9 7 1,000 1,23E-03 0,01693688 ! T cell lineage commitment GO:0002360 12 7 1,000 1,23E-03 0,01683606 ! response to tumor cell GO:0002347 12 7 1,000 1,23E-03 0,01673644 ! negative regulation of transferase activity GO:0051348 105 61 3,000 1,297E-03 0,01755174 ! regulation of B cell activation GO:0050864 42 28 2,000 1,308E-03 0,0175983 ! embryonic skeletal system morphogenesis GO:0048704 42 30 2,000 1,603E-03 0,02143844 ! embryonic epithelial tube formation GO:0001838 44 30 2,000 1,603E-03 0,02131452 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,603E-03 0,02119202 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,631E-03 0,02144036 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,631E-03 0,02131854 ! smoothened signaling pathway GO:0007224 8 8 1,000 1,631E-03 0,02119809 ! keratinocyte proliferation GO:0043616 12 8 1,000 1,631E-03 0,021079 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,631E-03 0,02096124 ! osteoblast development GO:0002076 13 8 1,000 1,631E-03 0,02084479 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 1,000 1,631E-03 0,02072963 ! regulation of embryonic development GO:0045995 16 8 1,000 1,631E-03 0,02061573 ! regulation of caspase activity GO:0043281 97 65 3,000 1,643E-03 0,02065327 ! odontogenesis GO:0042476 50 31 2,000 1,765E-03 0,02206201 ! metanephros development GO:0001656 58 31 2,000 1,765E-03 0,02194276 ! regulation of endopeptidase activity GO:0052548 99 67 3,000 1,838E-03 0,02273109 ! regulation of protein stability GO:0031647 48 32 2,000 1,937E-03 0,02381836 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 1,000 2,087E-03 0,02552934 ! regulation of developmental growth GO:0048638 13 9 1,000 2,087E-03 0,02539426 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 2,087E-03 0,02526061 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 1,000 2,087E-03 0,02512835 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 15 9 1,000 2,087E-03 0,02499748 ! lung alveolus development GO:0048286 17 9 1,000 2,087E-03 0,02486795 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 2,087E-03 0,02473977 ! ventral spinal cord development GO:0021517 11 9 1,000 2,087E-03 0,0246129 ! motor axon guidance GO:0008045 14 9 1,000 2,087E-03 0,02448732 ! localization within membrane GO:0051668 15 9 1,000 2,087E-03 0,02436302 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 2,118E-03 0,02460482 ! nucleus organization GO:0006997 49 33 2,000 2,118E-03 0,02448118 ! negative regulation of hydrolase activity GO:0051346 50 33 2,000 2,118E-03 0,02435878 ! regulation of catabolic process GO:0009894 106 70 3,000 2,16E-03 0,02471558 ! neuron migration GO:0001764 46 34 2,000 2,31E-03 0,02630217 ! dorsal/ventral pattern formation GO:0009953 44 34 2,000 2,31E-03 0,0261726 ! regulation of peptidase activity GO:0052547 106 72 3,000 2,395E-03 0,02699956 ! negative regulation of transport GO:0051051 116 73 3,000 2,518E-03 0,02825623 ! tube morphogenesis GO:0035239 118 73 3,000 2,518E-03 0,02811906 ! mitochondrion organization GO:0007005 104 73 3,000 2,518E-03 0,02798322 ! negative regulation of muscle development GO:0048635 12 10 1,000 2,595E-03 0,02869646 ! neuron fate specification GO:0048665 11 10 1,000 2,595E-03 0,02855915 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,595E-03 0,02842316 GO:0010812|negative regulation of cell-substrate adhesion, ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 2,595E-03 0,02828845 ! response to X-ray GO:0010165 16 10 1,000 2,595E-03 0,02815501 ! UV protection GO:0009650 14 10 1,000 2,595E-03 0,02802283 ! DNA methylation GO:0006306 15 10 1,000 2,595E-03 0,02789188 GO:0006305|DNA alkylation, ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 2,595E-03 0,02776215 GO:0043470|regulation of carbohydrate catabolic process, ! embryonic gut development GO:0048566 11 10 1,000 2,595E-03 0,02763362 ! response to reactive oxygen species GO:0000302 55 36 2,000 2,725E-03 0,02888504 ! neural tube development GO:0021915 50 36 2,000 2,725E-03 0,02875254 ! gland development GO:0048732 148 77 3,000 3,057E-03 0,03211036 ! virus-host interaction GO:0019048 17 11 1,000 3,156E-03 0,0329917 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,156E-03 0,03284241 ! regulation of intracellular pH GO:0051453 17 11 1,000 3,156E-03 0,03269447 ! male genitalia development GO:0030539 13 11 1,000 3,156E-03 0,03254786 ! digestive tract morphogenesis GO:0048546 15 11 1,000 3,156E-03 0,03240256 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of T cell proliferation GO:0042129 58 38 2,000 3,184E-03 0,03254433 ! morphogenesis of embryonic epithelium GO:0016331 60 39 2,000 3,43E-03 0,03490247 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 3,43E-03 0,03474872 ! protein localization in nucleus GO:0034504 133 80 3,000 3,51E-03 0,0354073 ! mRNA transport GO:0051028 121 81 3,000 3,67E-03 0,03686369 ! regulation of cell cycle process GO:0010564 122 81 3,000 3,67E-03 0,03670341 ! epidermal cell differentiation GO:0009913 53 40 2,000 3,687E-03 0,03670764 ! positive regulation of protein transport GO:0051222 55 40 2,000 3,687E-03 0,03654942 ! lactation GO:0007595 20 12 1,000 3,768E-03 0,03719114 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 3,768E-03 0,03703221 ! positive regulation of cell growth GO:0030307 16 12 1,000 3,768E-03 0,03687462 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 3,768E-03 0,03671838 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 20 12 1,000 3,768E-03 0,03656345 ! regulation of T cell differentiation GO:0045580 59 41 2,000 3,955E-03 0,03822419 ! regulation of JAK-STAT cascade GO:0046425 61 42 2,000 4,236E-03 0,04076142 ! embryonic skeletal system development GO:0048706 56 42 2,000 4,236E-03 0,04059159 ! cell differentiation in spinal cord GO:0021515 16 13 1,000 4,43E-03 0,04227828 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 4,43E-03 0,04210358 ! genitalia development GO:0048806 15 13 1,000 4,43E-03 0,04193031 ! regulation of cellular pH GO:0030641 20 13 1,000 4,43E-03 0,04175847 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 4,43E-03 0,04158802 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 4,528E-03 0,04233201 ! activation of caspase activity GO:0006919 65 43 2,000 4,528E-03 0,04216062 ! Wnt receptor signaling pathway GO:0016055 130 87 3,000 4,738E-03 0,04394292 ! establishment of RNA localization GO:0051236 128 88 3,000 4,934E-03 0,04557864 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 5,142E-03 0,04730758 ! neuron maturation GO:0042551 21 14 1,000 5,142E-03 0,04711911 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 5,142E-03 0,04693213 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of caspase activity GO:0043154 20 14 1,000 5,142E-03 0,04674662 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 5,142E-03 0,04656258 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 5,142E-03 0,04637998 ! hormone metabolic process GO:0042445 121 90 3,000 5,343E-03 0,04800332 ! histone modification GO:0016570 68 46 2,000 5,476E-03 0,04900523 ! RNA localization GO:0006403 135 91 3,000 5,556E-03 0,04952589 ! covalent chromatin modification GO:0016569 75 47 2,000 5,816E-03 0,0516503 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 2,000 5,816E-03 0,05145164 ! negative regulation of immune system process GO:0002683 73 47 2,000 5,816E-03 0,05125451 ! positive regulation of cell size GO:0045793 20 15 1,000 5,903E-03 0,05182131 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 5,903E-03 0,05162427 ! skin development GO:0043588 25 15 1,000 5,903E-03 0,05142872 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 5,903E-03 0,05123465 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 5,903E-03 0,05104204 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 5,903E-03 0,05085087 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 5,903E-03 0,05066113 ! positive regulation of caspase activity GO:0043280 72 48 2,000 6,169E-03 0,05274749 GO:0010952|positive regulation of peptidase activity, ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 6,169E-03 0,05255213 ! response to oxidative stress GO:0006979 141 94 3,000 6,227E-03 0,05284766 ! regulation of angiogenesis GO:0045765 94 49 2,000 6,535E-03 0,0552557 ! RNA elongation GO:0006354 62 49 2,000 6,535E-03 0,0550533 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 3,000 6,703E-03 0,05626691 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 6,712E-03 0,05613855 ! cellular response to hydrogen peroxide GO:0070301 21 16 1,000 6,712E-03 0,05593515 GO:0042744|hydrogen peroxide catabolic process, ! neural crest cell migration GO:0001755 24 16 1,000 6,712E-03 0,05573322 ! G1 phase GO:0051318 27 16 1,000 6,712E-03 0,05553274 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 6,712E-03 0,0553337 ! lipid modification GO:0030258 73 50 2,000 6,913E-03 0,05678252 ! positive regulation of growth GO:0045927 67 50 2,000 6,913E-03 0,05658045 ! regulation of protein catabolic process GO:0042176 77 51 2,000 7,303E-03 0,05956731 ! positive regulation of organelle organization GO:0010638 82 51 2,000 7,303E-03 0,05935683 ! forelimb morphogenesis GO:0035136 19 17 1,000 7,569E-03 0,06129526 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 7,569E-03 0,06108019 ! DNA duplex unwinding GO:0032508 25 17 1,000 7,569E-03 0,06086662 GO:0032392|DNA geometric change, ! neuromuscular junction development GO:0007528 23 17 1,000 7,569E-03 0,06065455 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 7,569E-03 0,06044394 ! proximal/distal pattern formation GO:0009954 25 17 1,000 7,569E-03 0,06023479 ! aging GO:0007568 79 52 2,000 7,707E-03 0,06112554 ! nucleotide-excision repair GO:0006289 64 52 2,000 7,707E-03 0,06091549 ! protein localization in organelle GO:0033365 161 100 3,000 7,727E-03 0,06086138 ! kidney development GO:0001822 90 53 2,000 8,124E-03 0,06376998 ! cAMP metabolic process GO:0046058 33 18 1,000 8,472E-03 0,06627435 ! somitogenesis GO:0001756 24 18 1,000 8,472E-03 0,06604969 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 8,472E-03 0,06582655 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 8,472E-03 0,06560491 ! regulation of mitosis GO:0007088 84 54 2,000 8,553E-03 0,06601603 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 2,000 8,553E-03 0,06579524 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 9,42E-03 0,07222252 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 9,42E-03 0,07198258 ! apoptotic nuclear changes GO:0030262 24 19 1,000 9,42E-03 0,07174422 ! sex determination GO:0007530 29 19 1,000 9,42E-03 0,07150745 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 9,42E-03 0,07127222 ! embryonic organ morphogenesis GO:0048562 23 19 1,000 9,42E-03 0,07103854 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 9,42E-03 0,07080639 ! protein stabilization GO:0050821 26 19 1,000 9,42E-03 0,07057575 ! hindlimb morphogenesis GO:0035137 32 20 1,000 0,01041409 0,07776755 ! spinal cord development GO:0021510 31 20 1,000 0,01041409 0,07751588 ! DNA modification GO:0006304 28 20 1,000 0,01041409 0,07726583 ! positive regulation of B cell activation GO:0050871 31 20 1,000 0,01041409 0,07701738 ! camera-type eye morphogenesis GO:0048593 34 20 1,000 0,01041409 0,07677053 ! phosphoinositide metabolic process GO:0030384 87 60 2,000 0,01140944 0,08383936 ! embryonic limb morphogenesis GO:0030326 86 60 2,000 0,01140944 0,08357236 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 0,01145213 0,0836187 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 1,000 0,01145213 0,08335409 ! dendrite development GO:0016358 35 21 1,000 0,01145213 0,08309114 ! cell aging GO:0007569 32 21 1,000 0,01145213 0,08282985 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 0,01145213 0,08257019 ! response to cytokine stimulus GO:0034097 47 21 1,000 0,01145213 0,08231216 ! meiosis GO:0007126 96 61 2,000 0,01193249 0,08549756 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 2,000 0,01193249 0,08523204 ! negative regulation of ligase activity GO:0051352 91 61 2,000 0,01193249 0,08496816 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! meiotic cell cycle GO:0051321 97 62 2,000 0,01246913 0,08851542 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 0,0125337 0,08870004 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,0125337 0,08842795 GO:0010810|regulation of cell-substrate adhesion, ! neural tube closure GO:0001843 33 22 1,000 0,0125337 0,08815753 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of transcription factor activity GO:0051090 97 63 2,000 0,01301943 0,09129476 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 0,01301943 0,09101727 ! appendage morphogenesis GO:0035107 93 64 2,000 0,01358343 0,09467237 GO:0035108|limb morphogenesis, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 0,01365808 0,09490511 ! neuron fate commitment GO:0048663 32 23 1,000 0,01365808 0,09461925 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01365808 0,09433511 ! myelination GO:0042552 35 23 1,000 0,01365808 0,09405267 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01365808 0,09377191 ! osteoblast differentiation GO:0001649 40 23 1,000 0,01365808 0,09349283 ! hydrogen peroxide metabolic process GO:0042743 30 23 1,000 0,01365808 0,0932154 ! interaction with host GO:0051701 37 23 1,000 0,01365808 0,09293962 ! negative regulation of catabolic process GO:0009895 34 23 1,000 0,01365808 0,09266546 ! appendage development GO:0048736 94 65 2,000 0,01416118 0,09579619 GO:0060173|limb development, ! protein oligomerization GO:0051259 100 65 2,000 0,01416118 0,09551527 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 0,01475271 0,09921416 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 0,01482455 0,09940661 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01482455 0,09911764 ! neural crest cell development GO:0014032 39 24 1,000 0,01482455 0,09883034 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 1,000 0,01482455 0,0985447 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01482455 0,09826071 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 0,01482455 0,09797835 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01482455 0,09769761 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01603239 0,10535572 ! response to drug GO:0042493 108 69 2,000 0,01661042 0,10884324 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 0,01725746 0,11276183 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 0,01725746 0,11244239 ! regulation of pH GO:0006885 36 26 1,000 0,0172809 0,11227705 ! circadian rhythm GO:0007623 42 26 1,000 0,0172809 0,11196078 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 0,0172809 0,11164628 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,0172809 0,11133355 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 0,01791844 0,11511848 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 1,000 0,01856939 0,11896821 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01856939 0,11863775 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 0,01859339 0,11846201 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 2,000 0,01859339 0,11813477 ! negative regulation of organelle organization GO:0010639 115 72 2,000 0,01859339 0,11780933 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01989715 0,12572378 ! mRNA export from nucleus GO:0006406 39 28 1,000 0,01989715 0,12537933 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01989715 0,12503677 GO:0008366|axon ensheathment, ! neural tube formation GO:0001841 41 28 1,000 0,01989715 0,12469607 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01989715 0,12435722 ! response to oxygen levels GO:0070482 137 74 2,000 0,01998523 0,12456918 ! protein import into nucleus GO:0006606 118 74 2,000 0,01998523 0,1242325 ! regulation of ligase activity GO:0051340 114 75 2,000 0,02070215 0,12834219 ! nuclear import GO:0051170 121 75 2,000 0,02070215 0,12799719 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,02126353 0,13111559 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,02126353 0,13076502 ! telencephalon development GO:0021537 52 29 1,000 0,02126353 0,13041631 ! eye morphogenesis GO:0048592 51 29 1,000 0,02126353 0,13006946 ! tissue homeostasis GO:0001894 42 29 1,000 0,02126353 0,12972445 GO:0048871|multicellular organismal homeostasis, ! regulation of DNA binding GO:0051101 119 77 2,000 0,02217805 0,13494581 ! spliceosome assembly GO:0000245 49 30 1,000 0,02266784 0,13756207 ! spindle organization GO:0007051 37 30 1,000 0,02266784 0,13720006 ! hindbrain development GO:0030902 45 30 1,000 0,02266784 0,13683996 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,02266784 0,13648174 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,02410941 0,14478238 ! segmentation GO:0035282 41 31 1,000 0,02410941 0,14440534 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,02410941 0,14403026 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,02410941 0,14365713 ! cell fate specification GO:0001708 37 31 1,000 0,02410941 0,14328592 ! forebrain development GO:0030900 131 80 2,000 0,02449705 0,14521444 ! regulation of muscle development GO:0048634 48 32 1,000 0,02558761 0,15128919 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,02558761 0,15090126 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,02558761 0,15051533 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,02558761 0,15013136 ! meiosis I GO:0007127 52 32 1,000 0,02558761 0,14974935 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,02558761 0,14936927 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02558761 0,14899112 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,02558761 0,14861488 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02558761 0,14824054 ! ossification GO:0001503 134 82 2,000 0,0261131 0,15090485 GO:0060348|bone development, ! regulation of cell adhesion GO:0030155 159 83 2,000 0,02694212 0,15530545 ! RNA export from nucleus GO:0006405 44 33 1,000 0,02710176 0,15583514 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02710176 0,15544653 ! sister chromatid segregation GO:0000819 46 33 1,000 0,02710176 0,15505984 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,02710176 0,15467508 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,02710176 0,15429222 ! cytokinesis GO:0000910 52 33 1,000 0,02710176 0,15391125 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,02778511 0,15740336 ! rRNA metabolic process GO:0016072 107 85 2,000 0,02864207 0,16185936 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 2,000 0,02864207 0,16146264 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,02865125 0,16111949 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,02865125 0,16072651 ! embryonic organ development GO:0048568 45 34 1,000 0,02865125 0,16033545 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,03023543 0,16879 ! cyclic nucleotide metabolic process GO:0009187 58 35 1,000 0,03023543 0,16838131 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,03023543 0,16797459 ! maintenance of protein location GO:0045185 65 35 1,000 0,03023543 0,16756983 ! glycogen metabolic process GO:0005977 48 35 1,000 0,03023543 0,16716702 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,03023543 0,16676614 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,03039778 0,16726049 GO:0060538|skeletal muscle organ development, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,03185367 0,17485309 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,03185367 0,17443678 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 0,03185367 0,17402244 ! glucan metabolic process GO:0044042 49 36 1,000 0,03185367 0,17361006 GO:0006073|cellular glucan metabolic process, ! reproductive developmental process GO:0003006 127 89 2,000 0,03220906 0,17513201 ! regulation of T cell activation GO:0050863 128 89 2,000 0,03220906 0,17471897 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,03350537 0,18132317 ! glycerophospholipid metabolic process GO:0006650 130 92 2,000 0,03502971 0,18912753 ! cell fate commitment GO:0045165 141 92 2,000 0,03502971 0,1886846 ! mesenchymal cell development GO:0014031 64 38 1,000 0,03518991 0,18910464 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 0,03518991 0,18866384 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,03690668 0,19740784 ! male sex differentiation GO:0046661 53 39 1,000 0,03690668 0,19694982 ! chromatin remodeling GO:0006338 68 39 1,000 0,03690668 0,19649392 ! developmental growth GO:0048589 62 39 1,000 0,03690668 0,19604012 ! synapse organization GO:0050808 55 39 1,000 0,03690668 0,19558841 ! regulation of binding GO:0051098 151 95 2,000 0,03797401 0,20078215 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03830096 0,20204635 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03830096 0,201584 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03830096 0,20112376 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03830096 0,20066562 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03830096 0,20020956 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03830096 0,19975557 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03830096 0,19930364 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03830096 0,19885374 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03830096 0,19840587 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03830096 0,19796002 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03830096 0,19751616 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03830096 0,19707429 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03830096 0,19663439 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 0,03830096 0,19619645 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03830096 0,19576046 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03830096 0,1953264 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03830096 0,19489426 ! cobalt ion transport GO:0006824 9 5 0,000 0,03830096 0,19446403 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03830096 0,1940357 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03830096 0,19360925 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03830096 0,19318466 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03830096 0,19276194 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03830096 0,19234106 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03830096 0,19192202 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03830096 0,1915048 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03830096 0,19108939 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03830096 0,19067577 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03830096 0,19026395 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03830096 0,18985389 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03830096 0,18944561 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03830096 0,18903907 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03830096 0,18863428 ! malate metabolic process GO:0006108 7 5 0,000 0,03830096 0,18823121 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03830096 0,18782987 ! behavioral response to pain GO:0048266 7 5 0,000 0,03830096 0,18743023 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03830096 0,18703229 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03830096 0,18663603 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03830096 0,18624145 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03830096 0,18584854 ! mating behavior GO:0007617 6 5 0,000 0,03830096 0,18545728 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03830096 0,18506766 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03830096 0,18467968 ! copulation GO:0007620 7 5 0,000 0,03830096 0,18429332 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03830096 0,18390857 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03830096 0,18352543 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03830096 0,18314388 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03830096 0,18276392 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03830096 0,18238552 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03830096 0,18200869 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03830096 0,18163342 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03830096 0,18125969 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03830096 0,18088749 ! response to protozoan GO:0001562 9 5 0,000 0,03830096 0,18051682 ! lymph vessel development GO:0001945 7 5 0,000 0,03830096 0,18014766 ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03830096 0,17978001 ! parathyroid gland development GO:0060017 8 5 0,000 0,03830096 0,17941386 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03830096 0,1790492 ! anagen GO:0042640 6 5 0,000 0,03830096 0,17868602 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03830096 0,17832431 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03830096 0,17796405 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03830096 0,17760526 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03830096 0,1772479 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03830096 0,17689198 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03830096 0,17653749 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03830096 0,17618441 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03830096 0,17583275 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03830096 0,17548248 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03830096 0,17513361 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03830096 0,17478613 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,03830096 0,17444001 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03830096 0,17409527 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03830096 0,17375189 ! ovulation GO:0030728 6 5 0,000 0,03830096 0,17340986 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03830096 0,17306917 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,03830096 0,17272982 ! response to pH GO:0009268 9 5 0,000 0,03830096 0,17239179 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03830096 0,17205509 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03830096 0,1717197 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03830096 0,17138562 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03830096 0,17105283 ! polyol catabolic process GO:0046174 7 5 0,000 0,03830096 0,17072133 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03830096 0,17039112 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03830096 0,17006218 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03830096 0,1697345 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03830096 0,16940809 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03830096 0,16908293 ! urea metabolic process GO:0019627 6 5 0,000 0,03830096 0,16875902 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03830096 0,16843634 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03830096 0,1681149 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03830096 0,16779468 ! neutrophil activation GO:0042119 5 5 0,000 0,03830096 0,16747568 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03830096 0,16715789 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03830096 0,1668413 ! response to food GO:0032094 5 5 0,000 0,03830096 0,16652591 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03830096 0,16621171 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03830096 0,1658987 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03830096 0,16558686 ! forebrain neuron development GO:0021884 7 5 0,000 0,03830096 0,16527619 ! melanosome organization GO:0032438 7 5 0,000 0,03830096 0,16496668 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03830096 0,16465833 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03830096 0,16435113 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03830096 0,16404508 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03830096 0,16374016 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03830096 0,16343638 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03830096 0,16313372 ! nucleoside transport GO:0015858 6 5 0,000 0,03830096 0,16283218 ! nucleoside salvage GO:0043174 7 5 0,000 0,03830096 0,16253175 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03830096 0,16223243 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03830096 0,1619342 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03830096 0,16163708 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03830096 0,16134104 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03830096 0,16104608 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03830096 0,1607522 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03830096 0,16045939 ! depyrimidination GO:0045008 8 5 0,000 0,03830096 0,16016765 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03830096 0,15987696 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03830096 0,15958733 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03830096 0,15929875 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03830096 0,1590112 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03830096 0,1587247 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03830096 0,15843922 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03830096 0,15815477 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03830096 0,15787134 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03830096 0,15758892 ! monocyte differentiation GO:0030224 8 5 0,000 0,03830096 0,15730751 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03830096 0,15702711 ! centrosome duplication GO:0051298 5 5 0,000 0,03830096 0,1567477 ! response to UV-C GO:0010225 6 5 0,000 0,03830096 0,15646928 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03830096 0,15619186 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03830096 0,15591541 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03830096 0,15563994 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03830096 0,15536544 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03830096 0,15509191 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03830096 0,15481934 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03830096 0,15454773 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03830096 0,15427707 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03830096 0,15400736 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03830096 0,15373858 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03830096 0,15347074 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03830096 0,15320384 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03830096 0,15293786 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03830096 0,1526728 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03830096 0,15240866 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03830096 0,15214544 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03830096 0,15188312 ! neural tube patterning GO:0021532 6 5 0,000 0,03830096 0,1516217 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03830096 0,15136118 ! histone demethylation GO:0016577 9 5 0,000 0,03830096 0,15110156 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03830096 0,15084282 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03830096 0,15058497 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03830096 0,150328 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03830096 0,1500719 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03830096 0,14981668 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03830096 0,14956232 ! transcription termination GO:0006353 8 5 0,000 0,03830096 0,14930883 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03830096 0,14905619 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03830096 0,1488044 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03830096 0,14855347 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03830096 0,14830338 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03830096 0,14805413 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03830096 0,14780572 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03830096 0,14755814 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03830096 0,14731138 ! apical protein localization GO:0045176 6 5 0,000 0,03830096 0,14706545 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03830096 0,14682035 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03830096 0,14657605 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03830096 0,14633257 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03830096 0,1460899 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03830096 0,14584803 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03830096 0,14560695 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03830096 0,14536668 ! glial cell migration GO:0008347 10 5 0,000 0,03830096 0,14512719 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03830096 0,1448885 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03830096 0,14465059 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03830096 0,14441345 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03830096 0,1441771 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03830096 0,14394151 ! neural plate development GO:0001840 6 5 0,000 0,03830096 0,1437067 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03830096 0,14347265 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03830096 0,14323936 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03830096 0,14300683 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03830096 0,14277505 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03830096 0,14254402 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03830096 0,14231374 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03830096 0,14208421 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03830096 0,14185541 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03830096 0,14162734 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03830096 0,14140001 ! spindle assembly GO:0051225 5 5 0,000 0,03830096 0,14117341 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03830096 0,14094753 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03830096 0,14072238 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03830096 0,14049794 ! organ regeneration GO:0031100 7 5 0,000 0,03830096 0,14027422 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03830096 0,1400512 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03830096 0,1398289 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03830096 0,1396073 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03830096 0,1393864 GO:0055081|anion homeostasis, ! T cell differentiation GO:0030217 65 40 1,000 0,0386551 0,14045298 ! double-strand break repair GO:0006302 67 40 1,000 0,0386551 0,14023144 ! B cell differentiation GO:0030183 62 40 1,000 0,0386551 0,14001061 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,0386551 0,13979046 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,04043458 0,14599611 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,04043458 0,14576728 ! endosome transport GO:0016197 71 41 1,000 0,04043458 0,14553916 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,04043458 0,14531176 ! biopolymer methylation GO:0043414 62 41 1,000 0,04043458 0,14508506 ! extracellular structure organization GO:0043062 156 99 2,000 0,04209028 0,15079072 ! protein import GO:0017038 156 99 2,000 0,04209028 0,15055621 ! mitochondrial transport GO:0006839 60 42 1,000 0,04224452 0,15087329 ! cellular component disassembly GO:0022411 64 42 1,000 0,04224452 0,15063938 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,04224452 0,15040619 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,04224452 0,15017373 ! positive regulation of binding GO:0051099 59 43 1,000 0,04408437 0,15647229 ! methylation GO:0032259 64 43 1,000 0,04408437 0,1562312 ! tRNA transcription GO:0009304 11 6 0,000 0,04578457 0,16200694 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04578457 0,16175808 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04578457 0,16150999 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04578457 0,16126265 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04578457 0,16101607 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04578457 0,16077025 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04578457 0,16052517 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04578457 0,16028084 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04578457 0,16003725 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04578457 0,1597944 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04578457 0,15955229 ! prostate gland development GO:0030850 9 6 0,000 0,04578457 0,15931091 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04578457 0,15907026 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04578457 0,15883034 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04578457 0,15859113 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04578457 0,15835265 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04578457 0,15811488 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04578457 0,15787783 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04578457 0,15764149 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04578457 0,15740585 ! neuron adhesion GO:0007158 9 6 0,000 0,04578457 0,15717091 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04578457 0,15693668 ! signal peptide processing GO:0006465 8 6 0,000 0,04578457 0,15670314 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04578457 0,1564703 ! mRNA stabilization GO:0048255 15 6 0,000 0,04578457 0,15623815 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04578457 0,15600669 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04578457 0,15577591 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04578457 0,15554581 ! opsonization GO:0008228 8 6 0,000 0,04578457 0,15531639 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04578457 0,15508765 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04578457 0,15485958 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04578457 0,15463218 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04578457 0,15440544 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04578457 0,15417937 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04578457 0,15395397 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04578457 0,15372922 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04578457 0,15350512 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04578457 0,15328168 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04578457 0,15305888 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04578457 0,15283674 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04578457 0,15261524 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04578457 0,15239437 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04578457 0,15217415 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04578457 0,15195456 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04578457 0,15173561 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04578457 0,15151728 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04578457 0,15129959 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04578457 0,15108251 ! thymic T cell selection GO:0045061 12 6 0,000 0,04578457 0,15086606 ! protein lipoylation GO:0009249 10 6 0,000 0,04578457 0,15065023 ! pigment granule organization GO:0048753 11 6 0,000 0,04578457 0,15043502 ! drug transport GO:0015893 6 6 0,000 0,04578457 0,15022042 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04578457 0,15000643 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04578457 0,14979305 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04578457 0,14958027 ! histidine metabolic process GO:0006547 6 6 0,000 0,04578457 0,1493681 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04578457 0,14915653 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04578457 0,14894556 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04578457 0,14873519 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04578457 0,14852541 ! adenohypophysis development GO:0021984 10 6 0,000 0,04578457 0,14831621 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04578457 0,14810761 ! hyperosmotic response GO:0006972 8 6 0,000 0,04578457 0,1478996 ! microtubule nucleation GO:0007020 10 6 0,000 0,04578457 0,14769216 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04578457 0,14748531 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04578457 0,14727904 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04578457 0,14707334 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04578457 0,14686822 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04578457 0,14666367 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04578457 0,14645968 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04578457 0,14625627 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04578457 0,14605342 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04578457 0,14585113 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04578457 0,14564939 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04578457 0,14544822 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04578457 0,1452476 ! neuron apoptosis GO:0051402 8 6 0,000 0,04578457 0,14504754 ! organic alcohol transport GO:0015850 9 6 0,000 0,04578457 0,14484802 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04578457 0,14464906 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04578457 0,14445063 ! carnitine transport GO:0015879 8 6 0,000 0,04578457 0,14425276 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04578457 0,14405542 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04578457 0,14385862 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04578457 0,14366236 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04578457 0,14346664 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04578457 0,14327145 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04578457 0,14307678 ! parturition GO:0007567 12 6 0,000 0,04578457 0,14288265 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04578457 0,14268904 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04578457 0,14249596 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04578457 0,1423034 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04578457 0,14211135 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04578457 0,14191983 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04578457 0,14172882 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04578457 0,14153832 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04578457 0,14134834 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04578457 0,14115886 ! macrophage differentiation GO:0030225 10 6 0,000 0,04578457 0,1409699 ! astrocyte development GO:0014002 14 6 0,000 0,04578457 0,14078143 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04578457 0,14059347 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04578457 0,14040602 ! interaction with symbiont GO:0051702 8 6 0,000 0,04578457 0,14021906 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04578457 0,1400326 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04578457 0,13984663 ! eating behavior GO:0042755 6 6 0,000 0,04578457 0,13966116 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04578457 0,13947618 ! response to copper ion GO:0046688 9 6 0,000 0,04578457 0,13929168 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04578457 0,13910768 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04578457 0,13892416 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04578457 0,13874112 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04578457 0,13855857 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04578457 0,13837649 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04578457 0,1381949 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04578457 0,13801378 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04578457 0,13783313 ! gas homeostasis GO:0033483 11 6 0,000 0,04578457 0,13765296 ! hair follicle maturation GO:0048820 7 6 0,000 0,04578457 0,13747325 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04578457 0,13729402 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04578457 0,13711525 ! Schwann cell development GO:0014044 14 6 0,000 0,04578457 0,13693695 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04578457 0,13675911 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04578457 0,13658173 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04578457 0,13640481 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04578457 0,13622835 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04578457 0,13605234 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04578457 0,13587679 ! histone ubiquitination GO:0016574 7 6 0,000 0,04578457 0,13570169 ! regulation of meiosis GO:0040020 10 6 0,000 0,04578457 0,13552704 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04578457 0,13535284 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04578457 0,13517909 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04578457 0,13500579 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04578457 0,13483292 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04578457 0,1346605 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04578457 0,13448852 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04578457 0,13431698 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04578457 0,13414588 ! receptor internalization GO:0031623 9 6 0,000 0,04578457 0,13397521 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04578457 0,13380497 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04578457 0,13363517 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04578457 0,1334658 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04578457 0,13329685 ! protein deubiquitination GO:0016579 8 6 0,000 0,04578457 0,13312833 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04578457 0,13296024 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04578457 0,13279258 ! axonal fasciculation GO:0007413 9 6 0,000 0,04578457 0,13262533 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04578457 0,13245851 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04578457 0,1322921 ! midbrain development GO:0030901 6 6 0,000 0,04578457 0,13212611 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04578457 0,13196054 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04578457 0,13179538 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04578457 0,13163064 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04578457 0,13146631 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04578457 0,13130238 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04578457 0,13113887 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04578457 0,13097576 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04578457 0,13081306 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04578457 0,13065076 ! adult feeding behavior GO:0008343 6 6 0,000 0,04578457 0,13048886 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04578457 0,13032737 ! blastocyst growth GO:0001832 15 6 0,000 0,04578457 0,13016627 ! pigment granule transport GO:0051904 12 6 0,000 0,04578457 0,13000557 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04578457 0,12984527 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04578457 0,12968536 ! catecholamine transport GO:0051937 7 6 0,000 0,04578457 0,12952585 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04578457 0,12936672 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04578457 0,12920799 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04578457 0,12904965 ! protein prenylation GO:0018342 10 6 0,000 0,04578457 0,12889169 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04578457 0,12873412 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04578457 0,12857694 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04578457 0,12842014 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04578457 0,12826372 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04578457 0,12810768 ! activation of adenylate cyclase activity GO:0007190 76 44 1,000 0,04595355 0,12842425 ! regulation of action potential GO:0001508 71 44 1,000 0,04595355 0,12826839 ! ribonucleoprotein complex assembly GO:0022618 70 44 1,000 0,04595355 0,12811292 ! cell maturation GO:0048469 60 45 1,000 0,0478515 0,13324266 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 1,000 0,04977766 0,13843848 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,04977766 0,13827129 ! cell redox homeostasis GO:0045454 63 46 1,000 0,04977766 0,13810449 ! positive regulation of cyclase activity GO:0031281 87 47 1,000 0,0517315 0,14335236 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,0517315 0,14317985 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05321037 0,14709598 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05321037 0,14691939 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05321037 0,14674323 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05321037 0,14656749 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05321037 0,14639217 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05321037 0,14621727 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05321037 0,14604279 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05321037 0,14586872 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05321037 0,14569507 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05321037 0,14552182 ! reproductive behavior GO:0019098 12 7 0,000 0,05321037 0,145349 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05321037 0,14517658 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,05321037 0,14500457 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05321037 0,14483296 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,05321037 0,14466177 ! oligopeptide transport GO:0006857 11 7 0,000 0,05321037 0,14449097 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05321037 0,14432058 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05321037 0,14415059 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,05321037 0,14398101 ! pericardium development GO:0060039 8 7 0,000 0,05321037 0,14381182 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05321037 0,14364302 ! fibril organization GO:0043206 13 7 0,000 0,05321037 0,14347462 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05321037 0,14330662 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05321037 0,14313901 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,05321037 0,14297179 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05321037 0,14280496 ! lipoprotein transport GO:0042953 9 7 0,000 0,05321037 0,14263853 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05321037 0,14247247 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05321037 0,14230681 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05321037 0,14214153 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05321037 0,14197663 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05321037 0,14181211 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05321037 0,14164798 ! chemosensory behavior GO:0007635 9 7 0,000 0,05321037 0,14148423 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,05321037 0,14132085 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05321037 0,14115785 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05321037 0,14099522 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05321037 0,14083297 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05321037 0,1406711 ! reflex GO:0060004 12 7 0,000 0,05321037 0,14050959 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05321037 0,14034846 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05321037 0,14018769 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05321037 0,14002729 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05321037 0,13986726 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05321037 0,1397076 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05321037 0,1395483 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05321037 0,13938936 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05321037 0,13923078 ! adrenal gland development GO:0030325 17 7 0,000 0,05321037 0,13907256 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05321037 0,1389147 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05321037 0,1387572 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05321037 0,13860006 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05321037 0,13844327 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05321037 0,13828684 ! endosome organization GO:0007032 10 7 0,000 0,05321037 0,13813076 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05321037 0,13797503 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05321037 0,13781966 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05321037 0,13766463 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,05321037 0,13750995 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05321037 0,13735562 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05321037 0,13720163 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05321037 0,13704799 ! galactose metabolic process GO:0006012 10 7 0,000 0,05321037 0,13689469 ! vesicle fusion GO:0006906 15 7 0,000 0,05321037 0,13674174 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05321037 0,13658912 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05321037 0,13643685 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05321037 0,13628492 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05321037 0,13613332 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05321037 0,13598206 ! retinol metabolic process GO:0042572 9 7 0,000 0,05321037 0,13583114 ! behavioral fear response GO:0001662 13 7 0,000 0,05321037 0,13568055 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05321037 0,13553029 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05321037 0,13538037 ! rRNA modification GO:0000154 12 7 0,000 0,05321037 0,13523078 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05321037 0,13508152 ! response to UV-B GO:0010224 11 7 0,000 0,05321037 0,13493259 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05321037 0,13478398 ! intermediate filament organization GO:0045109 11 7 0,000 0,05321037 0,1346357 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05321037 0,13448775 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05321037 0,13434013 ! fibrinolysis GO:0042730 9 7 0,000 0,05321037 0,13419282 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,05321037 0,13404584 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05321037 0,13389918 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05321037 0,13375285 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05321037 0,13360683 ! response to tropane GO:0014073 13 7 0,000 0,05321037 0,13346113 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,05321037 0,13331575 ! melanosome localization GO:0032400 10 7 0,000 0,05321037 0,13317068 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05321037 0,13302593 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05321037 0,13288149 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05321037 0,13273737 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05321037 0,13259356 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05321037 0,13245006 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05321037 0,13230687 ! mast cell activation GO:0045576 9 7 0,000 0,05321037 0,13216399 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05321037 0,13202142 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05321037 0,13187915 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05321037 0,1317372 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05321037 0,13159554 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05321037 0,13145419 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05321037 0,13131315 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05321037 0,13117241 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05321037 0,13103196 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05321037 0,13089182 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05321037 0,13075198 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05321037 0,13061244 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05321037 0,13047319 ! neuroblast proliferation GO:0007405 13 7 0,000 0,05321037 0,13033424 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05321037 0,13019559 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05321037 0,13005723 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,05321037 0,12991917 ! diuresis GO:0030146 12 7 0,000 0,05321037 0,12978139 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05321037 0,12964391 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05321037 0,12950672 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05321037 0,12936983 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,05321037 0,12923322 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05321037 0,12909689 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05321037 0,12896086 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05321037 0,12882511 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05321037 0,12868965 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05321037 0,12855447 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,05321037 0,12841957 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,05321037 0,12828496 ! lymph node development GO:0048535 9 7 0,000 0,05321037 0,12815063 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05321037 0,12801658 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05321037 0,12788282 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05321037 0,12774933 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05321037 0,12761612 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05321037 0,12748318 ! ATP catabolic process GO:0006200 10 7 0,000 0,05321037 0,12735053 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05321037 0,12721814 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,05321037 0,12708604 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05321037 0,12695421 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05321037 0,12682265 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05321037 0,12669136 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05321037 0,12656035 ! muscle adaptation GO:0043500 12 7 0,000 0,05321037 0,1264296 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05321037 0,12629913 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05321037 0,12616892 ! retina homeostasis GO:0001895 9 7 0,000 0,05321037 0,12603899 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05321037 0,12590932 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05321037 0,12577991 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05321037 0,12565077 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05321037 0,1255219 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05321037 0,12539329 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05321037 0,12526495 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,05371247 0,12631768 ! heart morphogenesis GO:0003007 65 48 1,000 0,05371247 0,12618865 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,05371247 0,12605989 ! positive regulation of lyase activity GO:0051349 88 48 1,000 0,05371247 0,12593139 ! nuclear export GO:0051168 69 48 1,000 0,05371247 0,12580315 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,05572004 0,13037243 ! maintenance of location GO:0051235 84 49 1,000 0,05572004 0,13023994 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,05775368 0,13485632 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,05775368 0,13471955 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,05981288 0,13938158 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,05981288 0,1392405 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06057881 0,14088094 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06057881 0,14073864 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,06057881 0,14059662 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06057881 0,14045489 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06057881 0,14031345 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06057881 0,14017229 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06057881 0,14003141 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06057881 0,13989082 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06057881 0,13975051 ! phosphate transport GO:0006817 10 8 0,000 0,06057881 0,13961047 ! N-glycan processing GO:0006491 12 8 0,000 0,06057881 0,13947072 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06057881 0,13933125 ! UTP metabolic process GO:0046051 8 8 0,000 0,06057881 0,13919206 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06057881 0,13905315 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06057881 0,13891451 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,06057881 0,13877615 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06057881 0,13863806 ! succinate metabolic process GO:0006105 14 8 0,000 0,06057881 0,13850025 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06057881 0,13836271 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,06057881 0,13822545 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,06057881 0,13808846 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06057881 0,13795174 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06057881 0,13781529 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06057881 0,1376791 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06057881 0,13754319 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06057881 0,13740755 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,06057881 0,13727217 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06057881 0,13713706 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06057881 0,13700222 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06057881 0,13686764 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06057881 0,13673332 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06057881 0,13659927 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06057881 0,13646548 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06057881 0,13633195 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06057881 0,13619868 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,06057881 0,13606568 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06057881 0,13593293 ! melanin metabolic process GO:0006582 12 8 0,000 0,06057881 0,13580044 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06057881 0,13566821 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06057881 0,13553624 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,06057881 0,13540452 ! macrophage activation GO:0042116 12 8 0,000 0,06057881 0,13527306 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06057881 0,13514186 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06057881 0,1350109 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06057881 0,13488021 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06057881 0,13474976 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,06057881 0,13461957 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06057881 0,13448963 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06057881 0,13435994 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06057881 0,13423049 ! ruffle organization GO:0031529 11 8 0,000 0,06057881 0,1341013 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06057881 0,13397236 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06057881 0,13384366 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06057881 0,13371521 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06057881 0,13358701 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06057881 0,13345906 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06057881 0,13333134 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,06057881 0,13320388 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06057881 0,13307665 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06057881 0,13294967 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,06057881 0,13282293 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,06057881 0,13269643 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06057881 0,13257017 ! segment specification GO:0007379 10 8 0,000 0,06057881 0,13244416 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,06057881 0,13231838 ! cellular extravasation GO:0045123 11 8 0,000 0,06057881 0,13219284 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06057881 0,13206754 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06057881 0,13194248 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06057881 0,13181765 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06057881 0,13169306 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06057881 0,1315687 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06057881 0,13144458 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06057881 0,13132069 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,06057881 0,13119704 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06057881 0,13107362 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06057881 0,13095043 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06057881 0,13082747 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06057881 0,13070474 ! icosanoid secretion GO:0032309 12 8 0,000 0,06057881 0,13058224 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,06057881 0,13045998 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06057881 0,13033794 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06057881 0,13021612 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06057881 0,13009454 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06057881 0,12997318 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06057881 0,12985205 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06057881 0,12973115 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06057881 0,12961047 ! sterol catabolic process GO:0016127 9 8 0,000 0,06057881 0,12949001 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06057881 0,12936978 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06057881 0,12924977 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06057881 0,12912998 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06057881 0,12901042 ! prophase GO:0051324 11 8 0,000 0,06057881 0,12889108 ! S phase GO:0051320 8 8 0,000 0,06057881 0,12877195 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06057881 0,12865305 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,06057881 0,12853437 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,06057881 0,1284159 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06057881 0,12829766 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06057881 0,12817963 ! hormone catabolic process GO:0042447 13 8 0,000 0,06057881 0,12806181 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06057881 0,12794422 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06057881 0,12782684 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06057881 0,12770967 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06057881 0,12759272 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06057881 0,12747599 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,06057881 0,12735946 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06057881 0,12724315 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06057881 0,12712706 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06057881 0,12701117 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06057881 0,1268955 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06057881 0,12678003 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06057881 0,12666478 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06057881 0,12654973 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06057881 0,12643489 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,06057881 0,12632027 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,06189711 0,12895231 ! establishment of organelle localization GO:0051656 85 52 1,000 0,06189711 0,12883561 ! cell projection assembly GO:0030031 76 53 1,000 0,06400587 0,13310442 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,06613865 0,13741545 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,06613865 0,13729143 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06789031 0,14080047 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06789031 0,14067362 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06789031 0,140547 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06789031 0,14042061 ! CTP metabolic process GO:0046036 9 9 0,000 0,06789031 0,14029445 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06789031 0,14016851 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,06789031 0,1400428 ! GTP metabolic process GO:0046039 9 9 0,000 0,06789031 0,13991731 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06789031 0,13979205 ! social behavior GO:0035176 14 9 0,000 0,06789031 0,13966701 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06789031 0,1395422 ! artery development GO:0060840 19 9 0,000 0,06789031 0,13941761 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,06789031 0,13929324 ! response to pain GO:0048265 16 9 0,000 0,06789031 0,13916909 ! protein complex disassembly GO:0043241 17 9 0,000 0,06789031 0,13904517 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06789031 0,13892146 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06789031 0,13879797 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06789031 0,13867471 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06789031 0,13855166 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06789031 0,13842883 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06789031 0,13830622 ! protein targeting to ER GO:0045047 19 9 0,000 0,06789031 0,13818382 ! T cell selection GO:0045058 18 9 0,000 0,06789031 0,13806165 ! endoderm development GO:0007492 12 9 0,000 0,06789031 0,13793968 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06789031 0,13781794 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06789031 0,1376964 ! arginine catabolic process GO:0006527 10 9 0,000 0,06789031 0,13757508 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,06789031 0,13745398 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06789031 0,13733309 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06789031 0,13721241 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06789031 0,13709194 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,06789031 0,13697169 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06789031 0,13685164 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06789031 0,1367318 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06789031 0,13661218 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06789031 0,13649276 ! mannose metabolic process GO:0006013 9 9 0,000 0,06789031 0,13637356 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06789031 0,13625456 ! receptor clustering GO:0043113 15 9 0,000 0,06789031 0,13613576 ! epithelial cell development GO:0002064 10 9 0,000 0,06789031 0,13601718 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06789031 0,1358988 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06789031 0,13578063 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06789031 0,13566266 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06789031 0,1355449 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06789031 0,13542734 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,06789031 0,13530998 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,06789031 0,13519283 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,06789031 0,13507588 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,06789031 0,13495914 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06789031 0,13484259 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06789031 0,13472625 ! DNA ligation GO:0006266 14 9 0,000 0,06789031 0,1346101 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06789031 0,13449416 ! response to amine stimulus GO:0014075 13 9 0,000 0,06789031 0,13437842 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06789031 0,13426287 ! erythrocyte development GO:0048821 11 9 0,000 0,06789031 0,13414753 ! renal water homeostasis GO:0003091 14 9 0,000 0,06789031 0,13403238 ! postreplication repair GO:0006301 11 9 0,000 0,06789031 0,13391743 ! mRNA cleavage GO:0006379 13 9 0,000 0,06789031 0,13380267 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06789031 0,13368812 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,06789031 0,13357376 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,06789031 0,13345959 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06789031 0,13334562 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06789031 0,13323184 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06789031 0,13311826 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06789031 0,13300487 ! acid secretion GO:0046717 14 9 0,000 0,06789031 0,13289168 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06789031 0,13277867 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06789031 0,13266586 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06789031 0,13255324 ! purine base metabolic process GO:0006144 18 9 0,000 0,06789031 0,13244082 ! oocyte differentiation GO:0009994 12 9 0,000 0,06789031 0,13232858 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,06789031 0,13221653 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06789031 0,13210467 ! spleen development GO:0048536 15 9 0,000 0,06789031 0,131993 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,06789031 0,13188152 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06789031 0,13177023 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06789031 0,13165912 ! detection of calcium ion GO:0005513 13 9 0,000 0,06789031 0,13154821 ! blastocyst formation GO:0001825 12 9 0,000 0,06789031 0,13143748 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06789031 0,13132693 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06789031 0,13121657 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06789031 0,1311064 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06789031 0,13099641 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06789031 0,13088661 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06789031 0,13077699 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,06789031 0,13066755 ! prepulse inhibition GO:0060134 14 9 0,000 0,06789031 0,1305583 ! embryonic placenta development GO:0001892 12 9 0,000 0,06789031 0,13044922 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06789031 0,13034033 ! insulin secretion GO:0030073 17 9 0,000 0,06789031 0,13023163 ! sequestering of metal ion GO:0051238 11 9 0,000 0,06789031 0,1301231 ! response to nicotine GO:0035094 16 9 0,000 0,06789031 0,13001476 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06789031 0,12990659 ! nucleus localization GO:0051647 15 9 0,000 0,06789031 0,1297986 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06789031 0,1296908 ! mesoderm development GO:0007498 76 55 1,000 0,06829498 0,13035556 ! chromosome segregation GO:0007059 83 57 1,000 0,07267627 0,13860317 ! camera-type eye development GO:0043010 88 57 1,000 0,07267627 0,13848833 ! developmental maturation GO:0021700 75 57 1,000 0,07267627 0,13837369 ! viral reproductive process GO:0022415 87 58 1,000 0,07490028 0,14249019 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,07490028 0,14237243 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07514533 0,14272028 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07514533 0,14260253 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07514533 0,14248496 ! thyroid gland development GO:0030878 19 10 0,000 0,07514533 0,1423676 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07514533 0,14225042 ! synapsis GO:0007129 13 10 0,000 0,07514533 0,14213344 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07514533 0,14201665 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,07514533 0,14190005 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07514533 0,14178364 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,07514533 0,14166743 ! sulfate transport GO:0008272 12 10 0,000 0,07514533 0,1415514 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07514533 0,14143557 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,07514533 0,14131992 ! androgen metabolic process GO:0008209 13 10 0,000 0,07514533 0,14120446 ! phospholipid efflux GO:0033700 16 10 0,000 0,07514533 0,14108919 ! hippocampus development GO:0021766 19 10 0,000 0,07514533 0,14097411 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,07514533 0,14085922 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07514533 0,14074451 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07514533 0,14062999 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07514533 0,14051566 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07514533 0,14040151 ! pathogenesis GO:0009405 13 10 0,000 0,07514533 0,14028755 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07514533 0,14017377 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07514533 0,14006018 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07514533 0,13994677 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07514533 0,13983354 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07514533 0,1397205 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07514533 0,13960764 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07514533 0,13949496 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07514533 0,13938247 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07514533 0,13927015 ! B cell proliferation GO:0042100 14 10 0,000 0,07514533 0,13915802 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07514533 0,13904607 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07514533 0,13893429 ! forebrain cell migration GO:0021885 17 10 0,000 0,07514533 0,1388227 ! lipid digestion GO:0044241 15 10 0,000 0,07514533 0,13871128 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07514533 0,13860005 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07514533 0,13848899 ! entry into host cell GO:0030260 20 10 0,000 0,07514533 0,13837811 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,07514533 0,13826741 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07514533 0,13815688 ! negative regulation of ossification GO:0030279 19 10 0,000 0,07514533 0,13804653 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07514533 0,13793636 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07514533 0,13782636 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,07514533 0,13771654 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07514533 0,1376069 ! regulation of organ growth GO:0046620 11 10 0,000 0,07514533 0,13749742 ! response to dsRNA GO:0043331 18 10 0,000 0,07514533 0,13738812 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07514533 0,137279 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07514533 0,13717005 ! embryonic axis specification GO:0000578 12 10 0,000 0,07514533 0,13706127 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07514533 0,13695266 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07514533 0,13684423 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07514533 0,13673597 ! fucose catabolic process GO:0019317 16 10 0,000 0,07514533 0,13662787 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07514533 0,13651995 ! protein sumoylation GO:0016925 12 10 0,000 0,07514533 0,1364122 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07514533 0,13630462 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07514533 0,13619721 ! zymogen activation GO:0031638 14 10 0,000 0,07514533 0,13608997 ! salivary gland development GO:0007431 22 10 0,000 0,07514533 0,1359829 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07514533 0,13587599 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07514533 0,13576925 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07514533 0,13566269 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07514533 0,13555628 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,07514533 0,13545005 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07514533 0,13534398 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07514533 0,13523808 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07514533 0,13513234 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07514533 0,13502677 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07514533 0,13492136 ! detection of bacterium GO:0016045 10 10 0,000 0,07514533 0,13481612 ! activation of innate immune response GO:0002218 10 10 0,000 0,07514533 0,13471104 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07514533 0,13460612 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07514533 0,13450137 ! developmental induction GO:0031128 13 10 0,000 0,07514533 0,13439678 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07514533 0,13429235 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,07514533 0,13418809 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07514533 0,13408399 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07514533 0,13398005 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,07714591 0,13744042 ! nucleoside monophosphate metabolic process GO:0009123 95 59 1,000 0,07714591 0,13733404 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,07941268 0,14125999 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 1,000 0,07941268 0,14115082 ! extracellular matrix organization GO:0030198 103 61 1,000 0,08170015 0,1451045 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,08170015 0,14499254 ! rRNA transcription GO:0009303 17 11 0,000 0,08234429 0,14602303 ! respiratory burst GO:0045730 14 11 0,000 0,08234429 0,14591053 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,08234429 0,14579821 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,08234429 0,14568605 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,08234429 0,14557407 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,08234429 0,14546227 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,08234429 0,14535063 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,08234429 0,14523916 ! RNA polyadenylation GO:0043631 19 11 0,000 0,08234429 0,14512787 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,08234429 0,14501675 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,08234429 0,14490579 ! mating GO:0007618 14 11 0,000 0,08234429 0,14479501 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,08234429 0,14468439 ! T cell proliferation GO:0042098 20 11 0,000 0,08234429 0,14457395 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,08234429 0,14446367 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,08234429 0,14435356 ! bone resorption GO:0045453 16 11 0,000 0,08234429 0,14424362 ! regulated secretory pathway GO:0045055 14 11 0,000 0,08234429 0,14413384 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,08234429 0,14402424 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,08234429 0,14391479 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,08234429 0,14380552 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,08234429 0,14369641 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,08234429 0,14358747 ! syncytium formation GO:0006949 15 11 0,000 0,08234429 0,14347869 ! plasma membrane organization GO:0007009 18 11 0,000 0,08234429 0,14337008 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,08234429 0,14326163 ! focal adhesion formation GO:0048041 24 11 0,000 0,08234429 0,14315334 ! mitotic spindle organization GO:0007052 15 11 0,000 0,08234429 0,14304522 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,08234429 0,14293726 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,08234429 0,14282946 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,08234429 0,14272183 ! adult heart development GO:0007512 11 11 0,000 0,08234429 0,14261436 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,08234429 0,14250705 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,08234429 0,1423999 ! temperature homeostasis GO:0001659 16 11 0,000 0,08234429 0,14229291 ! L-glutamate transport GO:0015813 16 11 0,000 0,08234429 0,14218609 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,08234429 0,14207942 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,08234429 0,14197292 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,08234429 0,14186657 ! stem cell development GO:0048864 29 11 0,000 0,08234429 0,14176038 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,08234429 0,14165435 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,08234429 0,14154848 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,08234429 0,14144277 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,08234429 0,14133722 ! vasoconstriction GO:0042310 15 11 0,000 0,08234429 0,14123182 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,08234429 0,14112658 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,08234429 0,1410215 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,08234429 0,14091657 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,08234429 0,1408118 ! ribosome assembly GO:0042255 13 11 0,000 0,08234429 0,14070718 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,08234429 0,14060272 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,08234429 0,14049842 ! chromatin silencing GO:0006342 19 11 0,000 0,08234429 0,14039427 ! nucleosome positioning GO:0016584 13 11 0,000 0,08234429 0,14029027 ! T cell homeostasis GO:0043029 20 11 0,000 0,08234429 0,14018643 ! regulation of isotype switching GO:0045191 19 11 0,000 0,08234429 0,14008274 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,08234429 0,13997921 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,08234429 0,13987583 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,08234429 0,1397726 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,08234429 0,13966952 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,08234429 0,1395666 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,08234429 0,13946382 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,08234429 0,1393612 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,08234429 0,13925873 ! cholesterol efflux GO:0033344 19 11 0,000 0,08234429 0,13915641 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,08234429 0,13905424 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,08234429 0,13895222 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,08234429 0,13885034 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,08234429 0,13874862 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,08234429 0,13864705 ! defense response to fungus GO:0050832 12 11 0,000 0,08234429 0,13854563 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,08234429 0,13844435 ! lysogeny GO:0030069 18 11 0,000 0,08234429 0,13834322 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,08234429 0,13824224 ! acrosome reaction GO:0007340 13 11 0,000 0,08234429 0,13814141 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,08234429 0,13804072 ! organelle localization GO:0051640 96 62 1,000 0,08400785 0,14072691 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,08633533 0,14452057 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,08633533 0,14441547 ! viral reproduction GO:0016032 92 63 1,000 0,08633533 0,14431052 ! regulation of lipase activity GO:0060191 109 63 1,000 0,08633533 0,14420572 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,08868217 0,14801814 ! reproductive cellular process GO:0048610 14 12 0,000 0,08948762 0,1492542 ! tRNA modification GO:0006400 14 12 0,000 0,08948762 0,14914604 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08948762 0,14903804 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08948762 0,1489302 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08948762 0,14882251 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08948762 0,14871498 ! non-recombinational repair GO:0000726 19 12 0,000 0,08948762 0,14860761 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08948762 0,14850039 ! peroxisomal transport GO:0043574 21 12 0,000 0,08948762 0,14839332 ! cartilage condensation GO:0001502 18 12 0,000 0,08948762 0,14828641 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08948762 0,14817965 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08948762 0,14807305 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08948762 0,1479666 ! heart looping GO:0001947 15 12 0,000 0,08948762 0,1478603 ! palate development GO:0060021 15 12 0,000 0,08948762 0,14775415 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08948762 0,14764816 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,08948762 0,14754232 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08948762 0,14743663 ! arginine metabolic process GO:0006525 13 12 0,000 0,08948762 0,14733109 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,08948762 0,14722571 ! methionine metabolic process GO:0006555 13 12 0,000 0,08948762 0,14712047 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08948762 0,14701538 ! Golgi organization GO:0007030 18 12 0,000 0,08948762 0,14691045 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,08948762 0,14680566 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08948762 0,14670102 ! monoamine transport GO:0015844 13 12 0,000 0,08948762 0,14659654 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08948762 0,1464922 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08948762 0,14638801 ! L-amino acid transport GO:0015807 20 12 0,000 0,08948762 0,14628396 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08948762 0,14618007 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08948762 0,14607632 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08948762 0,14597272 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08948762 0,14586927 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08948762 0,14576596 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08948762 0,1456628 ! cerebellum development GO:0021549 13 12 0,000 0,08948762 0,14555979 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08948762 0,14545692 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08948762 0,14535419 ! histone methylation GO:0016571 15 12 0,000 0,08948762 0,14525161 ! gland morphogenesis GO:0022612 23 12 0,000 0,08948762 0,14514918 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08948762 0,14504689 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08948762 0,14494474 ! regulation of epidermis development GO:0045682 17 12 0,000 0,08948762 0,14484274 ! intestinal absorption GO:0050892 19 12 0,000 0,08948762 0,14474088 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08948762 0,14463917 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08948762 0,1445376 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,08948762 0,14443617 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08948762 0,14433488 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,08948762 0,14423373 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08948762 0,14413273 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08948762 0,14403187 ! microspike assembly GO:0030035 23 12 0,000 0,08948762 0,14393114 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08948762 0,14383056 ! response to cold GO:0009409 14 12 0,000 0,08948762 0,14373012 ! B cell activation GO:0042113 104 65 1,000 0,09104792 0,14613413 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,09104792 0,14603222 ! axon guidance GO:0007411 99 66 1,000 0,09343214 0,14975186 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,09657576 0,15468262 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,09657576 0,15457498 ! cGMP metabolic process GO:0046068 16 13 0,000 0,09657576 0,15446748 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,09657576 0,15436014 ! water transport GO:0006833 17 13 0,000 0,09657576 0,15425295 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,09657576 0,1541459 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,09657576 0,154039 ! lipid localization GO:0010876 24 13 0,000 0,09657576 0,15393225 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,09657576 0,15382565 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,09657576 0,1537192 ! organelle fusion GO:0048284 28 13 0,000 0,09657576 0,15361289 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,09657576 0,15350673 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,09657576 0,15340072 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,09657576 0,15329485 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,09657576 0,15318913 ! response to hexose stimulus GO:0009746 19 13 0,000 0,09657576 0,15308356 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,09657576 0,15297813 ! glutamate metabolic process GO:0006536 18 13 0,000 0,09657576 0,15287284 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,09657576 0,1527677 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,09657576 0,15266271 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,09657576 0,15255786 ! NAD metabolic process GO:0019674 21 13 0,000 0,09657576 0,15245315 ! exocrine system development GO:0035272 27 13 0,000 0,09657576 0,15234859 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,09657576 0,15224417 ! bone mineralization GO:0030282 15 13 0,000 0,09657576 0,15213989 ! regulation of exocytosis GO:0017157 17 13 0,000 0,09657576 0,15203576 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,09657576 0,15193177 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,09657576 0,15182792 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,09657576 0,15172421 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,09657576 0,15162064 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,09657576 0,15151722 ! cellular pigmentation GO:0033059 24 13 0,000 0,09657576 0,15141393 ! tissue regeneration GO:0042246 21 13 0,000 0,09657576 0,15131079 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,09657576 0,15120779 ! cofactor transport GO:0051181 19 13 0,000 0,09657576 0,15110493 ! NADP metabolic process GO:0006739 18 13 0,000 0,09657576 0,1510022 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,09657576 0,15089962 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,09657576 0,15079718 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,09657576 0,15069487 ! gas transport GO:0015669 18 13 0,000 0,09657576 0,15059271 ! regulation of RNA stability GO:0043487 28 13 0,000 0,09657576 0,15049068 ! heme biosynthetic process GO:0006783 20 13 0,000 0,09657576 0,15038879 ! regulation of axon extension GO:0030516 23 13 0,000 0,09657576 0,15028704 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,09657576 0,15018542 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,09657576 0,15008395 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,09657576 0,14998261 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,09657576 0,1498814 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,09657576 0,14978034 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,09657576 0,14967941 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,09825433 0,15217843 ! rhythmic process GO:0048511 105 68 1,000 0,09825433 0,15207602 ! eye development GO:0001654 111 70 1,000 0,10314541 0,15953896 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,10360911 0,1601485 ! superoxide anion generation GO:0042554 18 14 0,000 0,10360911 0,16004094 ! regulation of S phase GO:0033261 18 14 0,000 0,10360911 0,15993353 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,10360911 0,15982626 ! myotube differentiation GO:0014902 21 14 0,000 0,10360911 0,15971914 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,10360911 0,15961216 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,10360911 0,15950533 ! inositol metabolic process GO:0006020 20 14 0,000 0,10360911 0,15939864 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,10360911 0,15929209 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,10360911 0,15918568 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,10360911 0,15907941 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,10360911 0,15897329 ! gene silencing by RNA GO:0031047 20 14 0,000 0,10360911 0,15886731 ! response to cAMP GO:0051591 19 14 0,000 0,10360911 0,15876147 ! limbic system development GO:0021761 25 14 0,000 0,10360911 0,15865577 ! startle response GO:0001964 21 14 0,000 0,10360911 0,15855021 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,10360911 0,15844479 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,10360911 0,15833951 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,10360911 0,15823437 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,10360911 0,15812937 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,10360911 0,15802451 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,10360911 0,15791979 ! glycine metabolic process GO:0006544 22 14 0,000 0,10360911 0,15781521 ! pituitary gland development GO:0021983 23 14 0,000 0,10360911 0,15771076 ! lysosomal transport GO:0007041 20 14 0,000 0,10360911 0,15760646 ! regulation of heart rate GO:0002027 23 14 0,000 0,10360911 0,15750229 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,10360911 0,15739826 ! embryo implantation GO:0007566 27 14 0,000 0,10360911 0,15729436 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,10360911 0,15719061 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,10360911 0,15708699 ! axon cargo transport GO:0008088 27 14 0,000 0,10360911 0,15698351 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,10360911 0,15688016 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,10360911 0,15677695 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,10360911 0,15667387 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,10360911 0,15657093 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,10360911 0,15646813 ! mRNA splice site selection GO:0006376 26 14 0,000 0,10360911 0,15636546 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,10360911 0,15626293 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,10360911 0,15616052 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,10360911 0,15605826 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,10360911 0,15595613 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,10360911 0,15585413 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,10360911 0,15575226 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,10360911 0,15565053 ! muscle maintenance GO:0046716 19 14 0,000 0,10360911 0,15554893 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,10360911 0,15544746 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,10360911 0,15534613 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,10360911 0,15524493 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,10360911 0,15514385 ! cell killing GO:0001906 20 14 0,000 0,10360911 0,15504292 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,10360911 0,15494211 ! cilium assembly GO:0042384 20 14 0,000 0,10360911 0,15484143 ! peptide hormone secretion GO:0030072 23 14 0,000 0,10360911 0,15474088 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,10561575 0,15763545 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,10561575 0,15753322 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,11058811 0,16484294 ! metencephalon development GO:0022037 19 15 0,000 0,11058811 0,16473618 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,11058811 0,16462955 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,11058811 0,16452307 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,11058811 0,16441672 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,11058811 0,1643105 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,11058811 0,16420443 ! bile acid metabolic process GO:0008206 22 15 0,000 0,11058811 0,16409849 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,11058811 0,16399269 ! adult walking behavior GO:0007628 25 15 0,000 0,11058811 0,16388702 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,11058811 0,16378149 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,11058811 0,1636761 ! myoblast differentiation GO:0045445 27 15 0,000 0,11058811 0,16357084 ! centrosome cycle GO:0007098 16 15 0,000 0,11058811 0,16346572 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,11058811 0,16336073 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,11058811 0,16325588 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,11058811 0,16315116 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,11058811 0,16304658 ! cerebral cortex development GO:0021987 29 15 0,000 0,11058811 0,16294213 ! response to osmotic stress GO:0006970 22 15 0,000 0,11058811 0,16283781 ! vesicle coating GO:0006901 25 15 0,000 0,11058811 0,16273363 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,11058811 0,16262958 ! DNA integration GO:0015074 22 15 0,000 0,11058811 0,16252566 ! peptide secretion GO:0002790 27 15 0,000 0,11058811 0,16242188 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,11058811 0,16231823 ! regulation of vasodilation GO:0042312 24 15 0,000 0,11058811 0,16221471 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,11058811 0,16211132 ! neuron recognition GO:0008038 22 15 0,000 0,11058811 0,16200806 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,11058811 0,16190494 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,11058811 0,16180195 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,11058811 0,16169908 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,11058811 0,16159635 ! biomineral formation GO:0031214 18 15 0,000 0,11058811 0,16149375 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,11058811 0,16139128 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,11058811 0,16128894 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,11058811 0,16118673 ! dopamine metabolic process GO:0042417 30 15 0,000 0,11058811 0,16108465 ! organic cation transport GO:0015695 19 15 0,000 0,11058811 0,1609827 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,11058811 0,16088087 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,11058811 0,16077918 ! defense response to virus GO:0051607 27 15 0,000 0,11058811 0,16067761 ! peptide hormone processing GO:0016486 19 15 0,000 0,11058811 0,16057617 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,11312126 0,16415073 ! protein secretion GO:0009306 27 16 0,000 0,11751317 0,17041633 ! hormone secretion GO:0046879 25 16 0,000 0,11751317 0,17030895 ! bone remodeling GO:0046849 24 16 0,000 0,11751317 0,1702017 ! endothelial cell migration GO:0043542 22 16 0,000 0,11751317 0,17009459 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,11751317 0,16998761 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,11751317 0,16988076 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,11751317 0,16977406 ! glial cell development GO:0021782 24 16 0,000 0,11751317 0,16966748 ! patterning of blood vessels GO:0001569 24 16 0,000 0,11751317 0,16956104 ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,11751317 0,16945473 ! protein polyubiquitination GO:0000209 26 16 0,000 0,11751317 0,16934856 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,11751317 0,16924252 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,11751317 0,16913661 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,11751317 0,16903083 ! fructose metabolic process GO:0006000 20 16 0,000 0,11751317 0,16892519 ! regulation of protein binding GO:0043393 27 16 0,000 0,11751317 0,16881967 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,11751317 0,16871429 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,11751317 0,16860904 ! protein export from nucleus GO:0006611 24 16 0,000 0,11751317 0,16850393 ! negative regulation of immune response GO:0050777 28 16 0,000 0,11751317 0,16839894 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,11751317 0,16829408 ! DNA replication initiation GO:0006270 25 16 0,000 0,11751317 0,16818936 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,11751317 0,16808476 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,11751317 0,1679803 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,11751317 0,16787596 ! diencephalon development GO:0021536 25 16 0,000 0,11751317 0,16777175 ! oogenesis GO:0048477 23 16 0,000 0,11751317 0,16766768 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,11751317 0,16756373 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,11751317 0,16745991 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,11751317 0,16735622 ! steroid catabolic process GO:0006706 22 16 0,000 0,11751317 0,16725266 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,11751317 0,16714922 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,11751317 0,16704592 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,11751317 0,16694274 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,11751317 0,16683969 ! sperm-egg recognition GO:0035036 16 16 0,000 0,11751317 0,16673677 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,11751317 0,16663397 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,11751317 0,1665313 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,11751317 0,16642875 ! negative regulation of translation GO:0017148 22 16 0,000 0,11751317 0,16632634 ! response to unfolded protein GO:0006986 99 76 1,000 0,11819978 0,16719527 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,12076036 0,17071225 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,12076036 0,17060739 ! sex differentiation GO:0007548 105 77 1,000 0,12076036 0,17050266 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,12076036 0,17039806 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,12333466 0,1739238 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,12333466 0,17381723 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,12438471 0,17518973 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,12438471 0,17508251 ! negative regulation of defense response GO:0031348 19 17 0,000 0,12438471 0,17497543 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,12438471 0,17486847 ! glycerol metabolic process GO:0006071 20 17 0,000 0,12438471 0,17476165 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,12438471 0,17465496 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,12438471 0,1745484 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,12438471 0,17444197 ! signal complex assembly GO:0007172 29 17 0,000 0,12438471 0,17433566 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,12438471 0,17422949 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,12438471 0,17412345 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,12438471 0,17401753 ! memory GO:0007613 25 17 0,000 0,12438471 0,17391175 ! keratinization GO:0031424 17 17 0,000 0,12438471 0,17380609 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,12438471 0,17370056 ! retinoid metabolic process GO:0001523 22 17 0,000 0,12438471 0,17359516 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,12438471 0,17348989 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,12438471 0,17338474 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,12438471 0,17327972 ! vacuolar transport GO:0007034 24 17 0,000 0,12438471 0,17317483 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,12438471 0,17307007 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,12438471 0,17296543 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,12438471 0,17286092 ! membrane budding GO:0006900 29 17 0,000 0,12438471 0,17275654 ! heme metabolic process GO:0042168 27 17 0,000 0,12438471 0,17265228 ! actin filament bundle formation GO:0051017 26 17 0,000 0,12438471 0,17254814 ! body fluid secretion GO:0007589 27 17 0,000 0,12438471 0,17244414 ! stem cell differentiation GO:0048863 36 17 0,000 0,12438471 0,17234026 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,12438471 0,1722365 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,12438471 0,17213287 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,12438471 0,17202936 ! sensory perception of pain GO:0019233 23 17 0,000 0,12438471 0,17192598 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,12438471 0,17182272 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,12438471 0,17171958 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,12438471 0,17161657 ! synaptogenesis GO:0007416 24 17 0,000 0,12438471 0,17151368 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,12438471 0,17141092 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,12438471 0,17130828 ! cell-cell junction organization GO:0045216 25 17 0,000 0,12438471 0,17120576 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,12438471 0,17110336 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,12438471 0,17100109 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,12438471 0,17089894 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,12438471 0,17079691 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,12438471 0,170695 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,12592231 0,17270204 ! T cell activation GO:0042110 134 79 1,000 0,12592231 0,17259912 ! regulation of lyase activity GO:0051339 133 79 1,000 0,12592231 0,17249632 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,12852296 0,17595406 GO:0010498|proteasomal protein catabolic process, ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,13113625 0,17942497 ! response to protein stimulus GO:0051789 111 81 1,000 0,13113625 0,1793183 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,13113625 0,17921175 GO:0002696|positive regulation of leukocyte activation, ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,13120312 0,17919667 ! positive regulation of translation GO:0045727 28 18 0,000 0,13120312 0,17909032 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,13120312 0,1789841 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,13120312 0,178878 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,13120312 0,17877203 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,13120312 0,17866619 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,13120312 0,17856047 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,13120312 0,17845487 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,13120312 0,1783494 ! axis specification GO:0009798 26 18 0,000 0,13120312 0,17824406 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,13120312 0,17813884 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,13120312 0,17803374 ! pancreas development GO:0031016 26 18 0,000 0,13120312 0,17792877 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,13120312 0,17782392 ! glutamine metabolic process GO:0006541 23 18 0,000 0,13120312 0,17771919 ! response to retinoic acid GO:0032526 25 18 0,000 0,13120312 0,17761459 ! pigmentation during development GO:0048066 31 18 0,000 0,13120312 0,17751011 ! central nervous system neuron development GO:0021954 30 18 0,000 0,13120312 0,17740575 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,13120312 0,17730152 ! fucose metabolic process GO:0006004 26 18 0,000 0,13120312 0,17719741 ! response to fungus GO:0009620 19 18 0,000 0,13120312 0,17709342 ! peptide cross-linking GO:0018149 31 18 0,000 0,13120312 0,17698955 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,13120312 0,17688581 ! heart process GO:0003015 27 18 0,000 0,13120312 0,17678218 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,13120312 0,17667868 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,13120312 0,1765753 ! visual learning GO:0008542 35 18 0,000 0,13120312 0,17647204 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,13120312 0,1763689 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,13120312 0,17626588 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,13120312 0,17616298 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,13120312 0,1760602 ! vitamin transport GO:0051180 24 18 0,000 0,13120312 0,17595754 ! hormone transport GO:0009914 27 18 0,000 0,13120312 0,175855 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,13120312 0,17575258 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,13120312 0,17565028 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,13120312 0,1755481 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,13120312 0,17544604 ! cell-cell recognition GO:0009988 20 18 0,000 0,13120312 0,17534409 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,13120312 0,17524227 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,13120312 0,17514056 ! regulation of glucose import GO:0046324 21 18 0,000 0,13120312 0,17503897 GO:0010827|regulation of glucose transport, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,13639935 0,1818658 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,13796884 0,18385187 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,13796884 0,18374541 ! positive regulation of ossification GO:0045778 30 19 0,000 0,13796884 0,18363908 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,13796884 0,18353286 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,13796884 0,18342678 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,13796884 0,18332081 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,13796884 0,18321497 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,13796884 0,18310925 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,13796884 0,18300365 ! regeneration GO:0031099 32 19 0,000 0,13796884 0,18289817 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,13796884 0,18279281 ! response to alkaloid GO:0043279 32 19 0,000 0,13796884 0,18268758 ! sensory perception of taste GO:0050909 23 19 0,000 0,13796884 0,18258246 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,13796884 0,18247747 ! smooth muscle contraction GO:0006939 36 19 0,000 0,13796884 0,1823726 ! peroxisome organization GO:0007031 29 19 0,000 0,13796884 0,18226785 ! digestive system process GO:0022600 30 19 0,000 0,13796884 0,18216322 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,13796884 0,1820587 ! response to vitamin A GO:0033189 26 19 0,000 0,13796884 0,18195431 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,13796884 0,18185004 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,13796884 0,18174589 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,13796884 0,18164186 ! plasma membrane fusion GO:0045026 23 19 0,000 0,13796884 0,18153794 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,13796884 0,18143415 ! cytolysis GO:0019835 20 19 0,000 0,13796884 0,18133047 ! renal system process GO:0003014 35 19 0,000 0,13796884 0,18122691 ! vasodilation GO:0042311 33 19 0,000 0,13796884 0,18112347 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,13796884 0,18102015 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,13796884 0,18091695 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,13796884 0,18081386 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,13796884 0,18071089 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,13796884 0,18060804 ! sarcomere organization GO:0045214 23 19 0,000 0,13796884 0,1805053 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,13796884 0,18040268 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,13796884 0,18030018 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,13796884 0,1801978 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,13796884 0,18009553 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,13796884 0,17999338 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,13796884 0,17989134 ! sterol metabolic process GO:0016125 120 84 1,000 0,13904848 0,18119632 ! regulation of membrane potential GO:0042391 128 85 1,000 0,14170888 0,18455856 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,14438021 0,18793123 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,14468224 0,18821785 ! iron ion transport GO:0006826 37 20 0,000 0,14468224 0,18811145 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,14468224 0,18800517 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,14468224 0,18789902 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,14468224 0,18779298 ! response to vitamin GO:0033273 29 20 0,000 0,14468224 0,18768706 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,14468224 0,18758126 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,14468224 0,18747558 ! response to ethanol GO:0045471 37 20 0,000 0,14468224 0,18737002 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,14468224 0,18726458 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,14468224 0,18715926 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,14468224 0,18705405 ! chromosome condensation GO:0030261 31 20 0,000 0,14468224 0,18694897 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,14468224 0,186844 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,14468224 0,18673915 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,14468224 0,18663441 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,14468224 0,1865298 ! pallium development GO:0021543 38 20 0,000 0,14468224 0,1864253 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,14468224 0,18632092 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,14468224 0,18621665 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,14468224 0,18611251 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,14468224 0,18600847 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,14468224 0,18590456 ! collagen catabolic process GO:0030574 25 20 0,000 0,14468224 0,18580076 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,14468224 0,18569708 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,14468224 0,18559351 ! alditol metabolic process GO:0019400 24 20 0,000 0,14468224 0,18549006 ! actin filament-based movement GO:0030048 34 20 0,000 0,14468224 0,18538672 ! female pregnancy GO:0007565 130 87 1,000 0,14706215 0,18833126 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,14975437 0,19167226 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,15134375 0,19359879 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,15134375 0,19349117 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,15134375 0,19338368 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,15134375 0,1932763 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,15134375 0,19316905 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,15134375 0,19306191 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,15134375 0,19295489 GO:0034105|positive regulation of tissue remodeling, ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,15134375 0,19284799 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,15134375 0,19274121 ! vesicle docking GO:0048278 27 21 0,000 0,15134375 0,19263455 ! phototransduction GO:0007602 25 21 0,000 0,15134375 0,192528 ! visual behavior GO:0007632 39 21 0,000 0,15134375 0,19242157 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,15134375 0,19231526 ! ovarian follicle development GO:0001541 30 21 0,000 0,15134375 0,19220907 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,15134375 0,19210299 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,15134375 0,19199703 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,15134375 0,19189119 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,15134375 0,19178547 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,15134375 0,19167986 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,15134375 0,19157437 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,15134375 0,19146899 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,15134375 0,19136373 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,15134375 0,19125858 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,15134375 0,19115355 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,15134375 0,19104864 ! fatty acid transport GO:0015908 30 21 0,000 0,15134375 0,19094384 ! immunoglobulin production GO:0002377 33 21 0,000 0,15134375 0,19083916 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,15134375 0,19073459 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,15134375 0,19063013 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,15134375 0,19052579 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,15134375 0,19042157 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,15134375 0,19031745 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,15134375 0,19021346 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,15134375 0,19010957 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,15134375 0,1900058 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,15134375 0,18990214 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,15134375 0,18979859 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,15134375 0,18969516 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,15134375 0,18959184 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,15134375 0,18948864 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,15245656 0,19077807 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,15245656 0,19067433 ! leukocyte differentiation GO:0002521 143 90 1,000 0,15516841 0,19396051 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,15795375 0,19733494 ! viral genome replication GO:0019079 29 22 0,000 0,15795375 0,19722781 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,15795375 0,1971208 ! leukocyte adhesion GO:0007159 38 22 0,000 0,15795375 0,1970139 ! molting cycle process GO:0022404 40 22 0,000 0,15795375 0,19690712 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,15795375 0,19680045 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,15795375 0,1966939 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,15795375 0,19658746 ! vasculogenesis GO:0001570 33 22 0,000 0,15795375 0,19648114 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,15795375 0,19637493 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,15795375 0,19626884 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,15795375 0,19616287 ! lysosome organization GO:0007040 37 22 0,000 0,15795375 0,196057 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,15795375 0,19595126 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,15795375 0,19584562 ! regulation of behavior GO:0050795 38 22 0,000 0,15795375 0,1957401 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,15795375 0,19563469 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,15795375 0,1955294 ! membrane depolarization GO:0051899 35 22 0,000 0,15795375 0,19542422 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,15795375 0,19531916 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,15795375 0,1952142 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,15795375 0,19510936 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,15795375 0,19500463 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,15795375 0,19490002 ! blastocyst development GO:0001824 37 22 0,000 0,15795375 0,19479551 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,15795375 0,19469112 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,16061981 0,19787122 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,16335876 0,20113766 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,16335876 0,20103005 ! embryonic pattern specification GO:0009880 31 23 0,000 0,16451265 0,20234176 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,16451265 0,20223361 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,16451265 0,20212558 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,16451265 0,20201766 ! vesicle targeting GO:0006903 32 23 0,000 0,16451265 0,20190986 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,16451265 0,20180218 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,16451265 0,20169461 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,16451265 0,20158715 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,16451265 0,20147981 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,16451265 0,20137258 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,16451265 0,20126547 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,16451265 0,20115847 ! cell fate determination GO:0001709 45 23 0,000 0,16451265 0,20105159 ! pentose metabolic process GO:0019321 31 23 0,000 0,16451265 0,20094481 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,16451265 0,20083816 ! spermatid development GO:0007286 33 23 0,000 0,16451265 0,20073161 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,16451265 0,20062518 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,16451265 0,20051886 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,16451265 0,20041265 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,16451265 0,20030656 ! telomere organization GO:0032200 32 23 0,000 0,16451265 0,20020057 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,16451265 0,2000947 ! regulation of amine transport GO:0051952 38 23 0,000 0,16451265 0,19998895 ! liver development GO:0001889 40 23 0,000 0,16451265 0,1998833 ! angiogenesis GO:0001525 149 95 1,000 0,16886168 0,20505906 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,17102082 0,20757145 ! initiation of viral infection GO:0019059 42 24 0,000 0,17102082 0,20746197 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,17102082 0,20735261 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,17102082 0,20724336 ! superoxide metabolic process GO:0006801 32 24 0,000 0,17102082 0,20713423 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,17102082 0,20702521 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,17102082 0,2069163 ! fat cell differentiation GO:0045444 37 24 0,000 0,17102082 0,20680752 ! sperm motility GO:0030317 27 24 0,000 0,17102082 0,20669884 ! vacuole organization GO:0007033 39 24 0,000 0,17102082 0,20659028 ! receptor metabolic process GO:0043112 37 24 0,000 0,17102082 0,20648183 ! response to toxin GO:0009636 38 24 0,000 0,17102082 0,2063735 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,17102082 0,20626528 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,17102082 0,20615718 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,17102082 0,20604918 ! glutathione metabolic process GO:0006749 29 24 0,000 0,17102082 0,20594131 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,17102082 0,20583354 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,17102082 0,20572589 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,17102082 0,20561835 ! in utero embryonic development GO:0001701 147 96 1,000 0,17162506 0,20623701 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,17162506 0,20612932 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,17747867 0,21304851 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,17747867 0,21293738 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,17747867 0,21282636 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,17747867 0,21271545 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,17747867 0,21260466 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,17747867 0,21249399 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,17747867 0,21238343 ! peptide transport GO:0015833 43 25 0,000 0,17747867 0,21227299 ! male gonad development GO:0008584 33 25 0,000 0,17747867 0,21216266 ! iron ion homeostasis GO:0055072 39 25 0,000 0,17747867 0,21205244 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,17747867 0,21194234 ! phospholipid transport GO:0015914 35 25 0,000 0,17747867 0,21183236 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,17747867 0,21172249 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,17747867 0,21161273 ! detection of light stimulus GO:0009583 30 25 0,000 0,17747867 0,21150308 ! leukocyte proliferation GO:0070661 39 25 0,000 0,17747867 0,21139355 GO:0032943|mononuclear cell proliferation, ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,17995948 0,21423747 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,18275144 0,21744869 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,18275144 0,21733626 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,18388659 0,2185732 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,18388659 0,2184603 ! translational initiation GO:0006413 43 26 0,000 0,18388659 0,21834752 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,18388659 0,21823485 ! post-embryonic development GO:0009791 42 26 0,000 0,18388659 0,2181223 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,18388659 0,21800987 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,18388659 0,21789755 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,18388659 0,21778535 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,18388659 0,21767326 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,18388659 0,21756129 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,18388659 0,21744943 ! regulation of coagulation GO:0050818 39 26 0,000 0,18388659 0,21733769 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,19024494 0,22473722 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,19024494 0,22462185 ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,19024494 0,2245066 ! membrane docking GO:0022406 39 27 0,000 0,19024494 0,22439147 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,19024494 0,22427645 ! catechol metabolic process GO:0009712 43 27 0,000 0,19024494 0,22416156 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,19024494 0,22404678 ! acute-phase response GO:0006953 42 27 0,000 0,19024494 0,22393212 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,19024494 0,22381758 ! myofibril assembly GO:0030239 36 27 0,000 0,19024494 0,22370315 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,19024494 0,22358884 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,19024494 0,22347465 ! natural killer cell activation GO:0030101 35 27 0,000 0,19024494 0,22336057 ! lipid oxidation GO:0034440 38 27 0,000 0,19024494 0,22324661 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,19024494 0,22313277 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,19024494 0,22301904 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,19024494 0,22290543 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,19024494 0,22279194 ! gene silencing GO:0016458 41 27 0,000 0,19024494 0,22267856 ! phenol metabolic process GO:0018958 44 28 0,000 0,19655412 0,22994632 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,19655412 0,22982942 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,19655412 0,22971264 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,19655412 0,22959597 ! cell junction assembly GO:0034329 56 28 0,000 0,19655412 0,22947943 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,19655412 0,229363 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,19655412 0,22924669 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,19655412 0,2291305 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,19655412 0,22901442 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,19655412 0,22889847 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,19655412 0,22878263 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,19655412 0,2286669 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,19655412 0,2285513 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,19655412 0,22843581 ! mesoderm formation GO:0001707 46 28 0,000 0,19655412 0,22832044 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,19655412 0,22820518 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,19655412 0,22809004 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,19655412 0,22797502 ! BMP signaling pathway GO:0030509 40 28 0,000 0,19655412 0,22786012 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,19655412 0,22774532 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,19655412 0,22763065 ! placenta development GO:0001890 37 28 0,000 0,19655412 0,22751609 ! regulation of innate immune response GO:0045088 38 29 0,000 0,20281449 0,23464454 ! ovulation cycle process GO:0022602 41 29 0,000 0,20281449 0,23452657 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,20281449 0,23440871 ! protein targeting to membrane GO:0006612 53 29 0,000 0,20281449 0,23429098 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,20281449 0,23417336 ! mismatch repair GO:0006298 34 29 0,000 0,20281449 0,23405586 ! muscle cell development GO:0055001 38 29 0,000 0,20281449 0,23393848 ! formation of primary germ layer GO:0001704 48 29 0,000 0,20281449 0,23382122 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,20281449 0,23370408 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,20281449 0,23358705 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,20902645 0,24062104 ! collagen metabolic process GO:0032963 40 30 0,000 0,20902645 0,24050067 ! organic anion transport GO:0015711 51 30 0,000 0,20902645 0,24038042 ! cholesterol transport GO:0030301 46 30 0,000 0,20902645 0,24026029 GO:0015918|sterol transport, ! pigment biosynthetic process GO:0046148 50 30 0,000 0,20902645 0,24014028 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,20902645 0,24002039 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,20902645 0,23990061 ! ceramide metabolic process GO:0006672 43 30 0,000 0,20902645 0,23978096 ! ovulation cycle GO:0042698 43 30 0,000 0,20902645 0,23966143 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,20902645 0,23954202 ! adult locomotory behavior GO:0008344 47 30 0,000 0,20902645 0,23942273 ! response to heat GO:0009408 41 30 0,000 0,20902645 0,23930355 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,20902645 0,23918449 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,20902645 0,23906556 ! glial cell differentiation GO:0010001 55 31 0,000 0,21519035 0,24599294 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,21519035 0,24587074 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,21519035 0,24574866 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,21519035 0,2456267 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,21519035 0,24550486 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,21519035 0,24538315 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,21519035 0,24526155 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,21519035 0,24514007 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,21519035 0,24501872 ! RNA modification GO:0009451 40 31 0,000 0,21519035 0,24489748 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,22130657 0,25173348 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,22130657 0,25160905 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,22130657 0,25148474 ! cytokine production GO:0001816 44 32 0,000 0,22130657 0,25136055 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,22130657 0,25123648 ! vesicle localization GO:0051648 47 32 0,000 0,22130657 0,25111253 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,22737547 0,25787159 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,22737547 0,25774449 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,22737547 0,25761752 ! ear morphogenesis GO:0042471 42 33 0,000 0,22737547 0,25749068 ! actomyosin structure organization GO:0031032 43 33 0,000 0,22737547 0,25736396 ! cell junction organization GO:0034330 63 33 0,000 0,22737547 0,25723737 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,22737547 0,2571109 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,22737547 0,25698456 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,22737547 0,25685834 ! female gonad development GO:0008585 49 33 0,000 0,22737547 0,25673224 ! positive regulation of cell development GO:0010720 54 33 0,000 0,22737547 0,25660627 ! lipid homeostasis GO:0055088 55 33 0,000 0,22737547 0,25648042 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,22737547 0,25635469 ! regulation of proteolysis GO:0030162 50 33 0,000 0,22737547 0,25622909 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,22737547 0,25610361 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,22737547 0,25597826 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,23339741 0,26262918 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,23339741 0,26250076 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,23339741 0,26237246 ! feeding behavior GO:0007631 45 34 0,000 0,23339741 0,26224428 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,23339741 0,26211624 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,23339741 0,26198831 ! female gamete generation GO:0007292 43 34 0,000 0,23339741 0,26186051 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,23339741 0,26173284 ! polyol metabolic process GO:0019751 44 34 0,000 0,23339741 0,26160529 ! aerobic respiration GO:0009060 47 34 0,000 0,23339741 0,26147786 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,23339741 0,26135056 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,23937277 0,26791113 ! Notch signaling pathway GO:0007219 56 35 0,000 0,23937277 0,26778082 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,23937277 0,26765064 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,23937277 0,26752058 GO:0032313|regulation of Rab GTPase activity, ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,23937277 0,26739066 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,23937277 0,26726086 ! pigment metabolic process GO:0042440 61 35 0,000 0,23937277 0,26713118 ! protein homooligomerization GO:0051260 52 35 0,000 0,23937277 0,26700163 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,24530188 0,27348247 ! tissue remodeling GO:0048771 62 36 0,000 0,24530188 0,27334997 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,24530188 0,27321759 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,24530188 0,27308535 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,25118512 0,27949965 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,25118512 0,27936449 ! learning GO:0007612 67 37 0,000 0,25118512 0,27922947 ! ion transmembrane transport GO:0034220 56 37 0,000 0,25118512 0,27909458 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,25118512 0,27895981 ! regulation of protein secretion GO:0050708 51 37 0,000 0,25118512 0,27882518 ! amino acid activation GO:0043038 52 37 0,000 0,25118512 0,27869068 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,25118512 0,2785563 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,25702283 0,28489277 ! gliogenesis GO:0042063 71 38 0,000 0,25702283 0,28475554 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,25702283 0,28461844 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,25702283 0,28448147 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,25702283 0,28434464 ! phagocytosis GO:0006909 60 38 0,000 0,25702283 0,28420793 ! pigmentation GO:0043473 74 38 0,000 0,25702283 0,28407136 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,26281536 0,29033397 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,26281536 0,29019459 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,26281536 0,29005534 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,26281536 0,28991622 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,26281536 0,28977724 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,26281536 0,28963839 ! JNK cascade GO:0007254 54 39 0,000 0,26281536 0,28949968 ! cell growth GO:0016049 61 39 0,000 0,26281536 0,28936109 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,26856306 0,29554786 ! response to calcium ion GO:0051592 58 40 0,000 0,26856306 0,29540652 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,26856306 0,29526531 ! regulation of tube size GO:0035150 60 40 0,000 0,26856306 0,29512424 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,26856306 0,2949833 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,26856306 0,2948425 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,26856306 0,29470183 ! peptide metabolic process GO:0006518 56 40 0,000 0,26856306 0,29456129 ! inner ear development GO:0048839 57 40 0,000 0,26856306 0,29442089 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,26856306 0,29428062 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,26856306 0,29414049 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,27426627 0,30024389 ! glucose transport GO:0015758 52 41 0,000 0,27426627 0,30010106 ! striated muscle contraction GO:0006941 62 41 0,000 0,27426627 0,29995835 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,27426627 0,29981579 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,27426627 0,29967336 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,27992534 0,30571143 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,27992534 0,30556634 ! hexose transport GO:0008645 54 42 0,000 0,27992534 0,30542138 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,27992534 0,30527656 ! excretion GO:0007588 63 42 0,000 0,27992534 0,30513188 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,27992534 0,30498734 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,27992534 0,30484293 ! regulation of cell shape GO:0008360 78 42 0,000 0,27992534 0,30469866 ! leukocyte migration GO:0050900 60 43 0,000 0,2855406 0,31066385 ! neuromuscular process GO:0050905 79 43 0,000 0,2855406 0,31051696 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,2855406 0,31037021 ! tRNA processing GO:0008033 49 43 0,000 0,2855406 0,31022361 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,2855406 0,31007714 ! vesicle organization GO:0016050 79 43 0,000 0,2855406 0,3099308 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,29111239 0,31582948 ! glycolysis GO:0006096 53 44 0,000 0,29111239 0,31568057 ! regulation of ion transport GO:0043269 57 44 0,000 0,29111239 0,31553181 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,29111239 0,31538318 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,29111239 0,3152347 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,29111239 0,31508635 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,29111239 0,31493814 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,29111239 0,31479008 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,29111239 0,31464215 ! positive regulation of defense response GO:0031349 59 45 0,000 0,29664105 0,32046708 ! regulation of translational initiation GO:0006446 64 45 0,000 0,29664105 0,32031662 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,29664105 0,32016631 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,29664105 0,32001614 ! cell recognition GO:0008037 58 45 0,000 0,29664105 0,31986611 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,3021269 0,3256288 ! regulation of ossification GO:0030278 71 46 0,000 0,3021269 0,32547628 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,3021269 0,32532391 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,30757028 0,33103025 ! viral infectious cycle GO:0019058 71 47 0,000 0,30757028 0,33087541 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,30757028 0,33072073 ! endocrine system development GO:0035270 83 47 0,000 0,30757028 0,33056619 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,30757028 0,33041179 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,30757028 0,33025753 ! chloride transport GO:0006821 67 48 0,000 0,31297151 0,33590036 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,31297151 0,33574369 ! response to temperature stimulus GO:0009266 62 48 0,000 0,31297151 0,33558716 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,31297151 0,33543079 ! gastrulation GO:0007369 73 48 0,000 0,31297151 0,33527455 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,31297151 0,33511847 GO:0019724|B cell mediated immunity, ! regulation of endocytosis GO:0030100 63 48 0,000 0,31297151 0,33496252 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,31297151 0,33480673 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,31833091 0,34038173 ! sensory perception of smell GO:0007608 61 49 0,000 0,31833091 0,34022356 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,31833091 0,34006554 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,31833091 0,33990766 ! germ cell development GO:0007281 68 49 0,000 0,31833091 0,33974993 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,31833091 0,33959235 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,31833091 0,33943491 ! cartilage development GO:0051216 70 49 0,000 0,31833091 0,33927762 ! regulation of actin filament length GO:0030832 72 50 0,000 0,32364881 0,34478568 ! ear development GO:0043583 72 50 0,000 0,32364881 0,34462605 ! membrane fusion GO:0006944 80 50 0,000 0,32364881 0,34446658 ! proton transport GO:0015992 75 50 0,000 0,32364881 0,34430725 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,32364881 0,34414807 ! hydrogen transport GO:0006818 77 51 0,000 0,32892553 0,34959738 ! adult behavior GO:0030534 80 51 0,000 0,32892553 0,3494359 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,32892553 0,34927457 ! transition metal ion transport GO:0000041 74 52 0,000 0,33416138 0,3546706 ! regulation of cellular component size GO:0032535 74 52 0,000 0,33416138 0,354507 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,33416138 0,35434356 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,33935668 0,35968681 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,33935668 0,35952113 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,33935668 0,3593556 ! single fertilization GO:0007338 59 53 0,000 0,33935668 0,35919023 ! amino acid transport GO:0006865 84 54 0,000 0,34451174 0,36447884 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,34451174 0,36431127 ! glucose catabolic process GO:0006007 66 54 0,000 0,34451174 0,36414384 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,34451174 0,36397657 ! detection of external stimulus GO:0009581 66 54 0,000 0,34451174 0,36380946 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,34451174 0,3636425 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,34451174 0,36347569 ! exocytosis GO:0006887 74 55 0,000 0,34962687 0,36870325 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,34962687 0,36853428 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,34962687 0,36836546 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,35470237 0,37354187 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,35470237 0,37337091 ! carbohydrate transport GO:0008643 74 57 0,000 0,35973855 0,37849893 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,35973855 0,37832586 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,35973855 0,37815295 ! secondary metabolic process GO:0019748 84 57 0,000 0,35973855 0,3779802 ! gonad development GO:0008406 79 57 0,000 0,35973855 0,37780761 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,36473571 0,38288094 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,36473571 0,38270626 ! actin filament organization GO:0007015 95 59 0,000 0,36969415 0,38773213 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,36969415 0,3875554 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,37461418 0,39253422 ! regulation of heart contraction GO:0008016 91 60 0,000 0,37461418 0,39235547 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,37461418 0,39217688 ! fertilization GO:0009566 68 60 0,000 0,37461418 0,39199846 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,37461418 0,3918202 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,37949608 0,3967459 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,37949608 0,39656564 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,37949608 0,39638555 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,37949608 0,39620562 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,37949608 0,39602585 ! amine catabolic process GO:0009310 90 62 0,000 0,38434015 0,40089902 ! neurotransmitter transport GO:0006836 81 62 0,000 0,38434015 0,40071729 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,38434015 0,40053572 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,38434015 0,40035432 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,38434015 0,40017308 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,39391596 0,40995778 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,39391596 0,40977237 ! hexose catabolic process GO:0019320 82 64 0,000 0,39391596 0,40958712 ! adaptive immune response GO:0002250 94 64 0,000 0,39391596 0,40940203 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,39864827 0,41413325 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,39864827 0,41394628 ! defense response to bacterium GO:0042742 73 65 0,000 0,39864827 0,41375949 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,39864827 0,41357285 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,39864827 0,41338639 ! activation of immune response GO:0002253 83 65 0,000 0,39864827 0,4132001 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,4033439 0,41787882 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,4033439 0,41769067 ! antigen processing and presentation GO:0019882 96 66 0,000 0,4033439 0,41750269 ! regulation of immune effector process GO:0002697 101 66 0,000 0,4033439 0,41731488 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,40800314 0,42194569 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,40800314 0,42175605 ! acute inflammatory response GO:0002526 92 68 0,000 0,41262625 0,42634339 ! learning or memory GO:0007611 123 68 0,000 0,41262625 0,42615195 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,41262625 0,42596067 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,41262625 0,42576957 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,41262625 0,42557865 ! inorganic anion transport GO:0015698 93 68 0,000 0,41262625 0,42538789 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,41721353 0,42992434 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,41721353 0,4297318 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,41721353 0,42953944 ! response to metal ion GO:0010038 103 70 0,000 0,42176524 0,43403134 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,42176524 0,43383723 ! humoral immune response GO:0006959 86 70 0,000 0,42176524 0,4336433 ! amine transport GO:0015837 101 70 0,000 0,42176524 0,43344953 ! muscle cell differentiation GO:0042692 104 71 0,000 0,42628166 0,43789541 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,42628166 0,43769992 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,42628166 0,43750461 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,42628166 0,43730947 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,43076306 0,44170979 ! regulation of blood pressure GO:0008217 107 73 0,000 0,43520972 0,44607057 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,43520972 0,44587187 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,43520972 0,44567335 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,43962189 0,44999125 ! digestion GO:0007586 97 74 0,000 0,43962189 0,44979108 ! blood coagulation GO:0007596 116 75 0,000 0,44399984 0,45406831 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,44399984 0,45386651 ! response to nutrient GO:0007584 104 75 0,000 0,44399984 0,45366488 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,44399984 0,45346343 ! amine biosynthetic process GO:0009309 97 76 0,000 0,44834384 0,45769678 ! tRNA metabolic process GO:0006399 95 76 0,000 0,44834384 0,45749372 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,44834384 0,45729084 ! protein ubiquitination GO:0016567 125 77 0,000 0,45265415 0,46148251 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,45265415 0,46127805 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,45265415 0,46107376 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,45693103 0,46522415 ! cellular respiration GO:0045333 107 79 0,000 0,46117473 0,46933711 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,46117473 0,46912953 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,46117473 0,46892214 ! chromatin assembly GO:0031497 102 80 0,000 0,46538551 0,47299455 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,46538551 0,47278563 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,46538551 0,4725769 ! hemostasis GO:0007599 125 81 0,000 0,46956363 0,47660915 ! regulation of neurological system process GO:0031644 122 81 0,000 0,46956363 0,47639892 ! vitamin metabolic process GO:0006766 103 81 0,000 0,46956363 0,47618886 ! detection of stimulus GO:0051606 108 82 0,000 0,47370933 0,48018134 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,47782286 0,4841377 ! regulation of defense response GO:0031347 117 84 0,000 0,48190448 0,48805826 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,48190448 0,48784345 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,48595443 0,49172688 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,48595443 0,49151064 ! nucleosome organization GO:0034728 114 87 0,000 0,49396029 0,49938842 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,49396029 0,49916901 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,49396029 0,49894978 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,49791668 0,50272535 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,49791668 0,50250476 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,49791668 0,50228437 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,50184236 0,50602255 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,50573757 0,50972674 ! ATP metabolic process GO:0046034 137 91 0,000 0,50960255 0,51339723 ! response to virus GO:0009615 122 91 0,000 0,50960255 0,51317245 ! positive regulation of immune response GO:0050778 121 92 0,000 0,51343753 0,51680801 ! DNA recombination GO:0006310 146 92 0,000 0,51343753 0,51658194 ! sulfur metabolic process GO:0006790 118 92 0,000 0,51343753 0,51635606 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,51724273 0,51995554 ! electron transport chain GO:0022900 123 94 0,000 0,52101839 0,52352219 ! carboxylic acid transport GO:0046942 147 95 0,000 0,52476474 0,52705629 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,528482 0,5305581 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,528482 0,53032661 ! protein maturation GO:0051604 129 96 0,000 0,528482 0,53009533 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,5321704 0,5335623 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,5321704 0,53332981 ! calcium ion transport GO:0006816 167 99 0,000 0,53946148 0,54040131 ! regulation of translation GO:0006417 151 100 0,000 0,54306461 0,54377388 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,54306461 0,54353726 ! divalent metal ion transport GO:0070838 171 100 0,000 0,54306461 0,54330083 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,54306461 0,54306461