pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6934-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 4,000 1,764E-10 4,308E-07 ! cell cycle checkpoint GO:0000075 145 71 8,000 5,804E-10 7,09E-07 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 4,000 1,048E-09 8,531E-07 ! cellular response to hormone stimulus GO:0032870 182 85 8,000 2,979E-09 1,819E-06 ! cellular response to extracellular stimulus GO:0031668 52 31 5,000 3,307E-08 1,616E-05 ! organ growth GO:0035265 15 7 3,000 4,837E-08 1,969E-05 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 4,837E-08 1,688E-05 GO:0046676|negative regulation of insulin secretion, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 6,000 6,233E-08 1,903E-05 ! DNA damage checkpoint GO:0000077 78 35 5,000 7,142E-08 1,939E-05 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 9,627E-08 2,352E-05 ! DNA damage response, signal transduction GO:0042770 136 62 6,000 1,13E-07 2,509E-05 ! positive regulation of MAP kinase activity GO:0043406 174 93 7,000 1,187E-07 2,417E-05 ! DNA integrity checkpoint GO:0031570 82 38 5,000 1,196E-07 2,248E-05 ! carbohydrate homeostasis GO:0033500 59 39 5,000 1,406E-07 2,454E-05 GO:0042593|glucose homeostasis, ! regulation of intracellular protein transport GO:0033157 86 42 5,000 2,227E-07 3,626E-05 ! hormone-mediated signaling GO:0009755 84 43 5,000 2,574E-07 3,931E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 3,000 2,86E-07 4,11E-05 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 5,000 3,895E-07 5,286E-05 ! cellular response to nutrient levels GO:0031669 45 27 4,000 6,132E-07 7,884E-05 ! response to UV GO:0009411 120 55 5,000 1,151E-06 1,406E-04 ! regulation of intracellular transport GO:0032386 108 57 5,000 1,426E-06 1,659E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 5,000 2,843E-06 3,157E-04 ! negative regulation of hormone secretion GO:0046888 26 17 3,000 3,134E-06 3,328E-04 ! activation of MAPK activity GO:0000187 124 67 5,000 3,726E-06 3,793E-04 ! positive regulation of hormone secretion GO:0046887 35 19 3,000 5,054E-06 4,939E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 6,287E-06 5,907E-04 ! N-terminal protein amino acid acetylation GO:0006474 14 7 2,000 7,929E-06 7,175E-04 ! G1 DNA damage checkpoint GO:0031571 20 7 2,000 7,929E-06 6,918E-04 ! cranial nerve morphogenesis GO:0021602 12 7 2,000 7,929E-06 6,68E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 8,479E-06 6,905E-04 ! cellular response to starvation GO:0009267 37 22 3,000 9,401E-06 7,409E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 9,466E-06 7,226E-04 ! ER overload response GO:0006983 13 8 2,000 1,263E-05 9,349E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,263E-05 9,074E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,263E-05 8,815E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 3,000 1,602E-05 1,087E-03 ! regulation of insulin secretion GO:0050796 42 25 3,000 1,602E-05 1,058E-03 ! regulation of protein transport GO:0051223 165 87 5,000 1,702E-05 1,094E-03 GO:0070201|regulation of establishment of protein localization, ! insulin receptor signaling pathway GO:0008286 66 27 3,000 2,202E-05 1,379E-03 ! response to starvation GO:0042594 47 27 3,000 2,202E-05 1,345E-03 ! regulation of DNA replication GO:0006275 105 56 4,000 2,509E-05 1,495E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 2,556E-05 1,487E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 3,000 2,556E-05 1,452E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 2,000 2,682E-05 1,489E-03 ! regulation of peptide secretion GO:0002791 52 29 3,000 2,951E-05 1,602E-03 ! regulation of protein localization GO:0032880 188 97 5,000 3,165E-05 1,681E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 3,354E-05 1,743E-03 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 3,000 3,388E-05 1,725E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 2,000 3,67E-05 1,83E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 4,872E-05 2,38E-03 ! cranial nerve development GO:0021545 23 12 2,000 4,872E-05 2,334E-03 ! histone acetylation GO:0016573 27 12 2,000 4,872E-05 2,289E-03 ! autonomic nervous system development GO:0048483 24 12 2,000 4,872E-05 2,246E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 4,872E-05 2,204E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 4,872E-05 2,164E-03 GO:0042130|negative regulation of T cell proliferation, ! triglyceride metabolic process GO:0006641 46 33 3,000 4,987E-05 2,175E-03 ! multicellular organism reproduction GO:0032504 123 65 4,000 5,187E-05 2,223E-03 GO:0048609|reproductive process in a multicellular organism, ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 3,000 5,624E-05 2,369E-03 ! negative regulation of cell growth GO:0030308 142 67 4,000 6,004E-05 2,486E-03 ! negative regulation of secretion GO:0051048 68 35 3,000 6,32E-05 2,573E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 6,918E-05 2,771E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 6,918E-05 2,726E-03 ! lung development GO:0030324 165 69 4,000 6,918E-05 2,683E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 7,413E-05 2,83E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 7,987E-05 3,002E-03 ! respiratory tube development GO:0030323 171 72 4,000 8,485E-05 3,141E-03 ! neutral lipid metabolic process GO:0006638 54 38 3,000 8,781E-05 3,202E-03 GO:0006639|acylglycerol metabolic process, ! cellular response to insulin stimulus GO:0032869 85 38 3,000 8,781E-05 3,155E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 9,671E-05 3,424E-03 ! respiratory system development GO:0060541 175 74 4,000 9,671E-05 3,375E-03 ! mitotic cell cycle checkpoint GO:0007093 76 39 3,000 9,738E-05 3,351E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 9,939E-05 3,372E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 2,000 9,939E-05 3,326E-03 ! G1/S transition checkpoint GO:0031575 37 15 2,000 9,939E-05 3,281E-03 ! mammary gland development GO:0030879 93 40 3,000 1,077E-04 3,507E-03 ! glycerol ether metabolic process GO:0006662 57 40 3,000 1,077E-04 3,461E-03 ! mRNA catabolic process GO:0006402 79 41 3,000 1,187E-04 3,767E-03 ! regulation of hormone secretion GO:0046883 69 41 3,000 1,187E-04 3,719E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 2,000 1,218E-04 3,766E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 1,218E-04 3,719E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! organic ether metabolic process GO:0018904 59 42 3,000 1,306E-04 3,939E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,758E-04 5,238E-03 ! nerve development GO:0021675 34 18 2,000 1,758E-04 5,175E-03 ! negative regulation of growth GO:0045926 168 85 4,000 1,864E-04 5,422E-03 ! regulation of gene-specific transcription GO:0032583 102 46 3,000 1,868E-04 5,368E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 2,032E-04 5,772E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 2,206E-04 6,194E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 2,39E-04 6,636E-03 ! phosphoinositide phosphorylation GO:0046854 40 20 2,000 2,434E-04 6,682E-03 ! protein amino acid acetylation GO:0006473 41 20 2,000 2,434E-04 6,607E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,434E-04 6,535E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 2,434E-04 6,464E-03 ! negative regulation of T cell activation GO:0050868 41 20 2,000 2,434E-04 6,394E-03 ! lipid phosphorylation GO:0046834 43 21 2,000 2,827E-04 7,347E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,827E-04 7,27E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 3,241E-04 8,247E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 3,259E-04 8,207E-03 ! ureteric bud development GO:0001657 50 22 2,000 3,259E-04 8,123E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 3,259E-04 8,041E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 3,259E-04 7,961E-03 ! gut development GO:0048565 44 22 2,000 3,259E-04 7,882E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 3,451E-04 8,264E-03 ! epithelial tube morphogenesis GO:0060562 114 54 3,000 3,483E-04 8,262E-03 ! positive regulation of DNA replication GO:0045740 44 23 2,000 3,73E-04 8,763E-03 ! cellular response to reactive oxygen species GO:0034614 35 23 2,000 3,73E-04 8,679E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 2,000 3,73E-04 8,597E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 3,733E-04 8,523E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 3,733E-04 8,444E-03 ! endochondral ossification GO:0001958 17 5 1,000 3,733E-04 8,367E-03 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! microvillus organization GO:0032528 8 5 1,000 3,733E-04 8,291E-03 GO:0030033|microvillus assembly, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 1,000 3,733E-04 8,216E-03 ! mRNA transcription GO:0009299 10 5 1,000 3,733E-04 8,143E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,733E-04 8,071E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,733E-04 8E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,733E-04 7,93E-03 ! regulation of chondrocyte differentiation GO:0032330 16 5 1,000 3,733E-04 7,862E-03 ! enteric nervous system development GO:0048484 8 5 1,000 3,733E-04 7,795E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 3,733E-04 7,729E-03 ! circadian behavior GO:0048512 15 5 1,000 3,733E-04 7,664E-03 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 3,733E-04 7,6E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 3,733E-04 7,537E-03 ! stem cell division GO:0017145 11 5 1,000 3,733E-04 7,475E-03 GO:0048103|somatic stem cell division, ! RNA catabolic process GO:0006401 103 55 3,000 3,738E-04 7,425E-03 ! regulation of multicellular organism growth GO:0040014 90 55 3,000 3,738E-04 7,365E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 4,244E-04 8,294E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 4,244E-04 8,228E-03 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 4,244E-04 8,164E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 4,584E-04 8,749E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 4,801E-04 9,092E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 4,801E-04 9,022E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 4,801E-04 8,953E-03 ! protein tetramerization GO:0051262 57 25 2,000 4,801E-04 8,885E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 5,402E-04 9,923E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 5,402E-04 9,849E-03 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 5,402E-04 9,776E-03 ! positive regulation of nuclear division GO:0051785 41 26 2,000 5,402E-04 9,704E-03 GO:0045840|positive regulation of mitosis, ! positive regulation of secretion GO:0051047 110 61 3,000 5,558E-04 9,911E-03 ! forebrain regionalization GO:0021871 9 6 1,000 5,577E-04 9,873E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 5,577E-04 9,802E-03 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 1,000 5,577E-04 9,732E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 5,577E-04 9,663E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 19 6 1,000 5,577E-04 9,595E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 5,577E-04 9,527E-03 ! ectodermal gut morphogenesis GO:0048567 16 6 1,000 5,577E-04 9,461E-03 GO:0007439|ectodermal gut development, ! negative regulation of B cell activation GO:0050869 14 6 1,000 5,577E-04 9,396E-03 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 2,000 6,05E-04 0,01012355 ! cellular response to oxidative stress GO:0034599 43 27 2,000 6,05E-04 0,01005469 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 6,05E-04 9,987E-03 ! skeletal system morphogenesis GO:0048705 118 63 3,000 6,283E-04 0,01030189 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 6,67E-04 0,01086318 ! spliceosomal snRNP biogenesis GO:0000387 40 28 2,000 6,745E-04 0,01091331 ! protein amino acid acylation GO:0043543 59 28 2,000 6,745E-04 0,01084151 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 6,745E-04 0,01077065 ! positive regulation of cell motion GO:0051272 157 65 3,000 7,073E-04 0,0112209 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 7,49E-04 0,01180475 ! regulation of helicase activity GO:0051095 16 7 1,000 7,776E-04 0,01217729 ! sleep GO:0030431 16 7 1,000 7,776E-04 0,01209972 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 7,776E-04 0,01202314 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 1,000 7,776E-04 0,01194753 ! rhythmic behavior GO:0007622 17 7 1,000 7,776E-04 0,01187285 ! spinal cord patterning GO:0021511 14 7 1,000 7,776E-04 0,01179911 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 7,776E-04 0,01172628 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 7,776E-04 0,01165434 ! male sex determination GO:0030238 15 7 1,000 7,776E-04 0,01158327 ! B cell lineage commitment GO:0002326 21 7 1,000 7,776E-04 0,01151307 ! T cell lineage commitment GO:0002360 16 7 1,000 7,776E-04 0,01144371 ! regulation of B cell activation GO:0050864 55 30 2,000 8,284E-04 0,01211881 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 9,13E-04 0,01327707 ! metanephros development GO:0001656 81 32 2,000 1,003E-03 0,01449802 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,033E-03 0,01483877 ! male meiosis GO:0007140 9 8 1,000 1,033E-03 0,014752 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,033E-03 0,01466623 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,033E-03 0,01458145 ! osteoblast development GO:0002076 17 8 1,000 1,033E-03 0,01449765 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 1,000 1,033E-03 0,01441481 ! DNA topological change GO:0006265 12 8 1,000 1,033E-03 0,0143329 ! response to tumor cell GO:0002347 16 8 1,000 1,033E-03 0,01425193 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,033E-03 0,01417186 ! positive regulation of gene-specific transcription GO:0043193 70 33 2,000 1,098E-03 0,01498883 ! response to ionizing radiation GO:0010212 74 33 2,000 1,098E-03 0,01490555 ! regulation of caspase activity GO:0043281 136 74 3,000 1,151E-03 0,01554026 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,322E-03 0,01774818 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 1,322E-03 0,0176512 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 20 9 1,000 1,322E-03 0,01755527 ! microtubule bundle formation GO:0001578 22 9 1,000 1,322E-03 0,01746037 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,322E-03 0,0173665 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 1,322E-03 0,01727363 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 1,335E-03 0,0173458 ! regulation of catabolic process GO:0009894 173 77 3,000 1,335E-03 0,01725403 ! negative regulation of hydrolase activity GO:0051346 66 36 2,000 1,418E-03 0,01823022 ! odontogenesis GO:0042476 74 37 2,000 1,536E-03 0,0196458 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,536E-03 0,01954348 ! response to hypoxia GO:0001666 178 81 3,000 1,61E-03 0,0203791 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 1,646E-03 0,02072852 ! regulation of developmental growth GO:0048638 16 10 1,000 1,646E-03 0,02062222 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,646E-03 0,02051701 ! smoothened signaling pathway GO:0007224 18 10 1,000 1,646E-03 0,02041286 ! lung alveolus development GO:0048286 26 10 1,000 1,646E-03 0,02030976 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,646E-03 0,0202077 ! motor axon guidance GO:0008045 22 10 1,000 1,646E-03 0,02010667 ! protein heterooligomerization GO:0051291 17 10 1,000 1,646E-03 0,02000663 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 1,646E-03 0,01990759 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,646E-03 0,01980952 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of fibrinolysis GO:0051917 20 10 1,000 1,646E-03 0,01971242 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 1,66E-03 0,01978337 ! embryonic skeletal system morphogenesis GO:0048704 68 38 2,000 1,66E-03 0,01968733 ! regulation of protein stability GO:0031647 77 38 2,000 1,66E-03 0,01959222 ! regulation of peptidase activity GO:0052547 150 82 3,000 1,684E-03 0,01978436 ! response to oxygen levels GO:0070482 183 83 3,000 1,761E-03 0,020588 ! negative regulation of transport GO:0051051 164 85 3,000 1,922E-03 0,02236216 ! nucleus organization GO:0006997 73 40 2,000 1,927E-03 0,0223082 ! negative regulation of muscle development GO:0048635 27 11 1,000 2,004E-03 0,02308979 ! neuron fate specification GO:0048665 18 11 1,000 2,004E-03 0,02298139 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,004E-03 0,022874 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 2,004E-03 0,02276761 ! keratinocyte proliferation GO:0043616 19 11 1,000 2,004E-03 0,0226622 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 2,004E-03 0,02255777 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of intracellular pH GO:0051453 21 11 1,000 2,004E-03 0,02245429 ! UV protection GO:0009650 20 11 1,000 2,004E-03 0,02235176 ! DNA methylation GO:0006306 19 11 1,000 2,004E-03 0,02225016 GO:0006305|DNA alkylation, ! embryonic gut development GO:0048566 19 11 1,000 2,004E-03 0,02214948 ! regulation of embryonic development GO:0045995 35 11 1,000 2,004E-03 0,02204971 ! embryonic epithelial tube formation GO:0001838 85 41 2,000 2,069E-03 0,02267147 ! mitochondrion organization GO:0007005 159 87 3,000 2,093E-03 0,02282769 ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,219E-03 0,02408931 ! dorsal/ventral pattern formation GO:0009953 75 42 2,000 2,219E-03 0,02398272 ! tube morphogenesis GO:0035239 194 89 3,000 2,274E-03 0,02447437 ! protein localization in nucleus GO:0034504 192 89 3,000 2,274E-03 0,02436702 ! regulation of cell cycle process GO:0010564 161 90 3,000 2,369E-03 0,02526812 ! regulation of T cell proliferation GO:0042129 80 43 2,000 2,374E-03 0,02521888 ! neuron migration GO:0001764 85 43 2,000 2,374E-03 0,02510971 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,395E-03 0,02521655 ! virus-host interaction GO:0019048 30 12 1,000 2,395E-03 0,02510833 ! ventral spinal cord development GO:0021517 25 12 1,000 2,395E-03 0,02500103 ! localization within membrane GO:0051668 26 12 1,000 2,395E-03 0,02489464 ! gland development GO:0048732 220 91 3,000 2,466E-03 0,02552384 ! response to reactive oxygen species GO:0000302 75 44 2,000 2,537E-03 0,02614647 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 2,705E-03 0,02777073 ! positive regulation of cell growth GO:0030307 24 13 1,000 2,819E-03 0,02881137 ! response to X-ray GO:0010165 28 13 1,000 2,819E-03 0,02869132 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,819E-03 0,02857227 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,819E-03 0,0284542 ! digestive tract morphogenesis GO:0048546 31 13 1,000 2,819E-03 0,02833711 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of protein transport GO:0051222 80 46 2,000 2,881E-03 0,02884722 ! neural tube development GO:0021915 91 47 2,000 3,064E-03 0,03055016 ! regulation of JAK-STAT cascade GO:0046425 76 48 2,000 3,253E-03 0,03230833 ! negative regulation of caspase activity GO:0043154 23 14 1,000 3,275E-03 0,0323929 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 3,275E-03 0,03226229 GO:0060675|ureteric bud morphogenesis, ! regulation of cellular pH GO:0030641 27 14 1,000 3,275E-03 0,03213272 ! response to gamma radiation GO:0010332 30 14 1,000 3,275E-03 0,03200419 ! male genitalia development GO:0030539 26 14 1,000 3,275E-03 0,03187668 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 3,45E-03 0,03344485 ! mRNA transport GO:0051028 185 100 3,000 3,466E-03 0,03346418 ! hormone metabolic process GO:0042445 171 100 3,000 3,466E-03 0,03333244 ! activation of caspase activity GO:0006919 95 50 2,000 3,654E-03 0,03500292 ! epidermal cell differentiation GO:0009913 87 50 2,000 3,654E-03 0,03486619 ! lactation GO:0007595 30 15 1,000 3,764E-03 0,03577674 ! negative regulation of immune system process GO:0002683 101 51 2,000 3,864E-03 0,03659289 ! morphogenesis of embryonic epithelium GO:0016331 106 52 2,000 4,083E-03 0,03850948 ! histone modification GO:0016570 104 52 2,000 4,083E-03 0,03836136 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 2,000 4,083E-03 0,03821438 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,284E-03 0,0399452 ! positive regulation of cell size GO:0045793 29 16 1,000 4,284E-03 0,03979332 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,284E-03 0,03964259 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,284E-03 0,03949299 ! positive regulation of growth GO:0045927 96 53 2,000 4,308E-03 0,03956725 ! regulation of angiogenesis GO:0045765 125 54 2,000 4,541E-03 0,04155035 ! embryonic skeletal system development GO:0048706 101 54 2,000 4,541E-03 0,04139531 ! covalent chromatin modification GO:0016569 115 54 2,000 4,541E-03 0,04124143 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 4,835E-03 0,04375229 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 4,835E-03 0,04359084 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 4,835E-03 0,04343058 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 4,835E-03 0,04327149 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 4,835E-03 0,04311357 GO:0031114|regulation of microtubule depolymerization, ! genitalia development GO:0048806 32 17 1,000 4,835E-03 0,04295679 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 4,835E-03 0,04280115 ! regulation of protein catabolic process GO:0042176 126 56 2,000 5,03E-03 0,04435772 ! RNA elongation GO:0006354 90 56 2,000 5,03E-03 0,04419816 ! positive regulation of caspase activity GO:0043280 108 57 2,000 5,285E-03 0,04627778 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 2,000 5,285E-03 0,0461125 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 5,418E-03 0,04710343 ! neural crest cell migration GO:0001755 41 18 1,000 5,418E-03 0,0469364 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 5,418E-03 0,04677054 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 5,418E-03 0,04660586 ! aging GO:0007568 112 58 2,000 5,548E-03 0,04756028 ! positive regulation of organelle organization GO:0010638 108 58 2,000 5,548E-03 0,04739399 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 6,031E-03 0,05133627 ! neuron maturation GO:0042551 46 19 1,000 6,031E-03 0,05115802 ! cellular response to hydrogen peroxide GO:0070301 25 19 1,000 6,031E-03 0,050981 GO:0042744|hydrogen peroxide catabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 1,000 6,031E-03 0,05080521 ! neuromuscular junction development GO:0007528 43 19 1,000 6,031E-03 0,05063062 ! proximal/distal pattern formation GO:0009954 33 19 1,000 6,031E-03 0,05045722 ! embryonic organ morphogenesis GO:0048562 34 19 1,000 6,031E-03 0,05028502 ! lipid modification GO:0030258 112 60 2,000 6,098E-03 0,05067324 ! DNA catabolic process GO:0006308 94 60 2,000 6,098E-03 0,05050146 ! kidney development GO:0001822 133 60 2,000 6,098E-03 0,05033085 ! skin development GO:0043588 42 20 1,000 6,674E-03 0,05489728 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 6,674E-03 0,05471306 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 6,674E-03 0,05453007 ! DNA duplex unwinding GO:0032508 30 20 1,000 6,674E-03 0,05434831 GO:0032392|DNA geometric change, ! viral reproductive process GO:0022415 132 62 2,000 6,679E-03 0,05421254 ! regulation of mitosis GO:0007088 112 63 2,000 6,982E-03 0,05648054 GO:0051783|regulation of nuclear division, ! cAMP metabolic process GO:0046058 41 21 1,000 7,347E-03 0,05923451 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 7,347E-03 0,05903966 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 7,347E-03 0,05884609 ! camera-type eye morphogenesis GO:0048593 47 21 1,000 7,347E-03 0,05865378 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 7,347E-03 0,05846272 ! hindlimb morphogenesis GO:0035137 47 22 1,000 8,049E-03 0,06384174 ! apoptotic nuclear changes GO:0030262 34 22 1,000 8,049E-03 0,06363514 ! cell aging GO:0007569 48 22 1,000 8,049E-03 0,06342986 ! G1 phase GO:0051318 44 22 1,000 8,049E-03 0,06322591 ! positive regulation of B cell activation GO:0050871 42 22 1,000 8,049E-03 0,06302326 ! response to cytokine stimulus GO:0034097 69 22 1,000 8,049E-03 0,06282191 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 8,049E-03 0,06262184 ! protein stabilization GO:0050821 41 22 1,000 8,049E-03 0,06242304 ! embryonic limb morphogenesis GO:0030326 139 67 2,000 8,273E-03 0,06395814 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ligase activity GO:0051352 116 68 2,000 8,616E-03 0,06640067 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 142 68 2,000 8,616E-03 0,06619186 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 8,78E-03 0,06723874 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 8,78E-03 0,06702861 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 8,78E-03 0,0668198 GO:0010810|regulation of cell-substrate adhesion, ! DNA modification GO:0006304 36 23 1,000 8,78E-03 0,06661229 ! urogenital system development GO:0001655 149 69 2,000 8,967E-03 0,06782476 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 8,967E-03 0,06761542 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 9,539E-03 0,07170716 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 9,539E-03 0,0714872 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 9,539E-03 0,07126859 ! sex determination GO:0007530 48 24 1,000 9,539E-03 0,0710513 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 9,539E-03 0,07083534 ! negative regulation of catabolic process GO:0009895 52 24 1,000 9,539E-03 0,07062069 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 9,539E-03 0,07040733 ! appendage morphogenesis GO:0035107 150 72 2,000 0,01007137 0,07410953 GO:0035108|limb morphogenesis, ! negative regulation of DNA replication GO:0008156 45 25 1,000 0,0103272 0,07576381 ! interaction with host GO:0051701 66 25 1,000 0,0103272 0,07553698 ! appendage development GO:0048736 151 73 2,000 0,0104561 0,07625152 GO:0060173|limb development, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 0,01114278 0,0810173 ! myelination GO:0042552 50 26 1,000 0,01114278 0,08077689 ! osteoblast differentiation GO:0001649 63 26 1,000 0,01114278 0,08053791 ! neural crest cell development GO:0014032 59 26 1,000 0,01114278 0,08030034 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 83 26 1,000 0,01114278 0,08006416 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 1,000 0,01114278 0,07982937 ! spinal cord development GO:0021510 54 26 1,000 0,01114278 0,07959595 ! neural tube closure GO:0001843 58 26 1,000 0,01114278 0,07936389 GO:0060606|tube closure, ! regulation of transcription factor activity GO:0051090 137 75 2,000 0,01125088 0,07990086 GO:0090046|regulation of transcription regulator activity, ! tube lumen formation GO:0035148 59 27 1,000 0,0119858 0,08487338 ! mitochondrial membrane organization GO:0007006 60 27 1,000 0,0119858 0,08462808 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,0119858 0,08438419 ! phosphoinositide metabolic process GO:0030384 146 77 2,000 0,01207961 0,08480028 ! neuron fate commitment GO:0048663 52 28 1,000 0,0128559 0,0899913 ! circadian rhythm GO:0007623 56 28 1,000 0,0128559 0,08973418 ! dendrite development GO:0016358 67 28 1,000 0,0128559 0,08947852 ! base-excision repair GO:0006284 41 28 1,000 0,0128559 0,08922432 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01294253 0,08957113 ! protein oligomerization GO:0051259 149 79 2,000 0,01294253 0,0893181 ! negative regulation of organelle organization GO:0010639 181 80 2,000 0,01338687 0,09212431 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 1,000 0,01375271 0,09437603 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! primary neural tube formation GO:0014020 61 29 1,000 0,01375271 0,09411167 ! somitogenesis GO:0001756 52 29 1,000 0,01375271 0,09384879 ! meiosis GO:0007126 143 81 2,000 0,01383983 0,09418024 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 2,000 0,01383983 0,09391863 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 0,01383983 0,09365847 ! protein import into nucleus GO:0006606 174 82 2,000 0,01430143 0,09651488 ! meiotic cell cycle GO:0051321 144 82 2,000 0,01430143 0,096249 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 0,01467587 0,09849768 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01467587 0,09822782 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 0,01467587 0,09795944 GO:0048871|multicellular organismal homeostasis, ! response to drug GO:0042493 149 83 2,000 0,01477168 0,09833029 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 0,01477168 0,09806309 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 2,000 0,01477168 0,09779734 ! regulation of ligase activity GO:0051340 147 84 2,000 0,01525061 0,10069525 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01562503 0,10288937 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01562503 0,10261278 GO:0008366|axon ensheathment, ! eye morphogenesis GO:0048592 65 31 1,000 0,01562503 0,10233768 ! cholesterol metabolic process GO:0008203 148 85 2,000 0,01573823 0,10280349 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01659984 0,10814242 ! spindle organization GO:0007051 50 32 1,000 0,01659984 0,10785481 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01659984 0,10756872 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01659984 0,10728415 ! hindbrain development GO:0030902 65 32 1,000 0,01659984 0,10700108 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01659984 0,1067195 ! regulation of pH GO:0006885 56 33 1,000 0,01759994 0,11285213 ! regulation of DNA binding GO:0051101 167 89 2,000 0,01777594 0,11368225 ! response to hydrogen peroxide GO:0042542 56 34 1,000 0,018625 0,11880122 ! spliceosome assembly GO:0000245 75 34 1,000 0,018625 0,11849184 ! cell fate specification GO:0001708 56 34 1,000 0,018625 0,11818407 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,018625 0,1178779 ! ossification GO:0001503 205 91 2,000 0,01884728 0,11897651 ! bone development GO:0060348 206 92 2,000 0,01939611 0,12212548 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01939611 0,12181153 ! mRNA export from nucleus GO:0006406 53 35 1,000 0,01967466 0,12324408 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01967466 0,12292888 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01967466 0,12261529 ! telencephalon development GO:0021537 81 35 1,000 0,01967466 0,12230329 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01967466 0,12199288 ! sterol metabolic process GO:0016125 166 94 2,000 0,02052009 0,12691289 ! regulation of muscle development GO:0048634 82 36 1,000 0,02074859 0,12800204 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,02074859 0,12767962 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,02074859 0,12735881 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,02074859 0,12703962 ! embryonic organ development GO:0048568 67 36 1,000 0,02074859 0,12672202 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02167923 0,1320757 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,02184646 0,13276341 ! sister chromatid segregation GO:0000819 65 37 1,000 0,02184646 0,13243397 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,02184646 0,13210617 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,02184646 0,13177998 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,02184646 0,1314554 ! transcription initiation GO:0006352 171 97 2,000 0,02227198 0,13368661 ! forebrain development GO:0030900 210 98 2,000 0,02287352 0,13696084 ! meiosis I GO:0007127 74 38 1,000 0,02296792 0,13718981 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,02296792 0,1368552 ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 0,02296792 0,13652221 ! glycogen metabolic process GO:0005977 63 38 1,000 0,02296792 0,13619085 ! neural tube formation GO:0001841 79 38 1,000 0,02296792 0,13586109 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,02410298 0,14223087 GO:0060538|skeletal muscle organ development, ! negative regulation of binding GO:0051100 71 39 1,000 0,02411266 0,14194511 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,02411266 0,14160389 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,02411266 0,14126432 GO:0006073|cellular glucan metabolic process, ! lipid homeostasis GO:0055088 75 40 1,000 0,02528034 0,14775086 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02528034 0,14739824 ! RNA export from nucleus GO:0006405 61 41 1,000 0,02647064 0,15397087 ! mesenchymal cell development GO:0014031 94 41 1,000 0,02647064 0,15360514 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,02647064 0,15324115 ! maintenance of protein location GO:0045185 95 41 1,000 0,02647064 0,15287888 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,02768324 0,15950507 ! T cell differentiation GO:0030217 93 42 1,000 0,02768324 0,15912976 ! cytokinesis GO:0000910 84 42 1,000 0,02768324 0,15875622 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,02768324 0,15838442 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02891782 0,1650613 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02891782 0,16467654 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,02891782 0,16429357 ! segmentation GO:0035282 78 43 1,000 0,02891782 0,16391238 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,03017407 0,17063718 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,03017407 0,1702431 ! double-strand break repair GO:0006302 85 44 1,000 0,03017407 0,16985083 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03043128 0,17090489 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03043128 0,17051291 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03043128 0,17012272 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03043128 0,16973431 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03043128 0,16934767 ! neuron fate determination GO:0048664 7 5 0,000 0,03043128 0,16896279 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03043128 0,16857966 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03043128 0,16819825 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03043128 0,16781857 ! polyol transport GO:0015791 12 5 0,000 0,03043128 0,1674406 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03043128 0,16706433 ! response to superoxide GO:0000303 10 5 0,000 0,03043128 0,16668975 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03043128 0,16631684 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03043128 0,1659456 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03043128 0,16557601 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03043128 0,16520806 ! female meiosis GO:0007143 10 5 0,000 0,03043128 0,16484175 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,03043128 0,16447705 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03043128 0,16411397 ! hypothalamus development GO:0021854 9 5 0,000 0,03043128 0,16375249 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03043128 0,16339259 ! cobalt ion transport GO:0006824 11 5 0,000 0,03043128 0,16303427 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03043128 0,16267752 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03043128 0,16232233 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03043128 0,16196869 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03043128 0,16161658 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03043128 0,161266 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03043128 0,16091694 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03043128 0,16056939 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03043128 0,16022334 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03043128 0,15987877 ! transposition GO:0032196 9 5 0,000 0,03043128 0,15953568 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,03043128 0,15919406 ! negative chemotaxis GO:0050919 16 5 0,000 0,03043128 0,15885391 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03043128 0,1585152 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03043128 0,15817793 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03043128 0,1578421 ! behavioral response to pain GO:0048266 10 5 0,000 0,03043128 0,15750769 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03043128 0,15717469 ! Notch receptor processing GO:0007220 11 5 0,000 0,03043128 0,1568431 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03043128 0,1565129 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03043128 0,15618409 ! micturition GO:0060073 9 5 0,000 0,03043128 0,15585666 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03043128 0,1555306 ! copulation GO:0007620 9 5 0,000 0,03043128 0,1552059 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03043128 0,15488256 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03043128 0,15456056 ! bioluminescence GO:0008218 9 5 0,000 0,03043128 0,15423989 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03043128 0,15392056 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03043128 0,15360254 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03043128 0,15328583 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03043128 0,15297043 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03043128 0,15265632 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03043128 0,1523435 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03043128 0,15203196 ! grooming behavior GO:0007625 6 5 0,000 0,03043128 0,15172169 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03043128 0,15141268 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03043128 0,15110494 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03043128 0,15079843 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03043128 0,15049317 ! response to protozoan GO:0001562 13 5 0,000 0,03043128 0,15018915 ! lymph vessel development GO:0001945 10 5 0,000 0,03043128 0,14988635 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03043128 0,14958477 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03043128 0,14928439 ! single strand break repair GO:0000012 8 5 0,000 0,03043128 0,14898523 ! parathyroid gland development GO:0060017 14 5 0,000 0,03043128 0,14868726 ! anagen GO:0042640 7 5 0,000 0,03043128 0,14839048 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03043128 0,14809488 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03043128 0,14780045 ! cytokine secretion GO:0050663 15 5 0,000 0,03043128 0,1475072 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03043128 0,14721511 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03043128 0,14692417 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03043128 0,14663438 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03043128 0,14634572 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03043128 0,14605821 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03043128 0,14577182 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03043128 0,14548655 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03043128 0,1452024 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03043128 0,14491935 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,03043128 0,14463741 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03043128 0,14435656 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,03043128 0,1440768 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03043128 0,14379812 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03043128 0,14352052 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03043128 0,14324399 ! valine metabolic process GO:0006573 12 5 0,000 0,03043128 0,14296852 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03043128 0,1426941 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03043128 0,14242074 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03043128 0,14214843 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03043128 0,14187715 ! polyol catabolic process GO:0046174 9 5 0,000 0,03043128 0,14160691 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03043128 0,1413377 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03043128 0,1410695 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03043128 0,14080233 ! muscle cell migration GO:0014812 8 5 0,000 0,03043128 0,14053616 ! mitochondrial fission GO:0000266 8 5 0,000 0,03043128 0,140271 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03043128 0,14000683 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03043128 0,13974366 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03043128 0,13948148 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03043128 0,13922028 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03043128 0,13896005 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03043128 0,1387008 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03043128 0,13844251 ! monocyte activation GO:0042117 10 5 0,000 0,03043128 0,13818518 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03043128 0,13792881 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03043128 0,13767339 ! response to food GO:0032094 6 5 0,000 0,03043128 0,13741891 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03043128 0,13716537 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03043128 0,13691276 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03043128 0,13666108 ! forebrain neuron development GO:0021884 13 5 0,000 0,03043128 0,13641033 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03043128 0,13616049 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03043128 0,13591157 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03043128 0,13566356 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03043128 0,13541644 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03043128 0,13517023 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03043128 0,13492492 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03043128 0,13468049 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03043128 0,13443694 ! lipid glycosylation GO:0030259 7 5 0,000 0,03043128 0,13419427 ! nucleobase transport GO:0015851 6 5 0,000 0,03043128 0,13395248 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03043128 0,13371156 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03043128 0,1334715 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03043128 0,13323231 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03043128 0,13299397 ! basic amino acid transport GO:0015802 12 5 0,000 0,03043128 0,13275648 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03043128 0,13251984 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03043128 0,13228404 ! actin nucleation GO:0045010 11 5 0,000 0,03043128 0,13204907 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03043128 0,13181494 ! depurination GO:0045007 5 5 0,000 0,03043128 0,13158164 ! depyrimidination GO:0045008 10 5 0,000 0,03043128 0,13134917 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03043128 0,13111751 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03043128 0,13088667 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03043128 0,13065664 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03043128 0,13042742 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03043128 0,130199 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03043128 0,12997138 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03043128 0,12974455 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03043128 0,12951852 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03043128 0,12929327 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03043128 0,1290688 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03043128 0,12884511 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03043128 0,12862219 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03043128 0,12840005 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03043128 0,12817867 ! response to arsenic GO:0046685 11 5 0,000 0,03043128 0,12795805 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03043128 0,12773819 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03043128 0,12751909 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03043128 0,12730073 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03043128 0,12708313 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03043128 0,12686626 ! response to mercury ion GO:0046689 8 5 0,000 0,03043128 0,12665013 ! response to cadmium ion GO:0046686 7 5 0,000 0,03043128 0,12643474 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03043128 0,12622008 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03043128 0,12600615 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03043128 0,12579294 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03043128 0,12558045 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03043128 0,12536868 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03043128 0,12515762 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03043128 0,12494727 ! decidualization GO:0046697 11 5 0,000 0,03043128 0,12473763 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03043128 0,12452869 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03043128 0,12432045 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03043128 0,1241129 ! embryonic cleavage GO:0040016 6 5 0,000 0,03043128 0,12390605 ! peroxisome fission GO:0016559 5 5 0,000 0,03043128 0,12369988 ! histone demethylation GO:0016577 13 5 0,000 0,03043128 0,1234944 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03043128 0,1232896 ! mitotic recombination GO:0006312 9 5 0,000 0,03043128 0,12308548 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03043128 0,12288203 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03043128 0,12267925 ! metaphase plate congression GO:0051310 7 5 0,000 0,03043128 0,12247715 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03043128 0,1222757 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03043128 0,12207492 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03043128 0,1218748 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03043128 0,12167533 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03043128 0,12147652 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03043128 0,12127835 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03043128 0,12108083 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03043128 0,12088395 ! B cell homeostasis GO:0001782 13 5 0,000 0,03043128 0,12068771 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03043128 0,1204921 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03043128 0,12029713 ! metaphase GO:0051323 11 5 0,000 0,03043128 0,12010279 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03043128 0,11990908 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03043128 0,11971599 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03043128 0,11952352 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03043128 0,11933167 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03043128 0,11914043 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03043128 0,11894981 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03043128 0,11875979 ! response to redox state GO:0051775 6 5 0,000 0,03043128 0,11857038 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03043128 0,11838157 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03043128 0,11819337 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03043128 0,11800576 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03043128 0,11781875 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03043128 0,11763232 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03043128 0,11744649 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03043128 0,11726124 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03043128 0,11707658 GO:0033015|tetrapyrrole catabolic process, ! striatum development GO:0021756 14 5 0,000 0,03043128 0,1168925 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03043128 0,11670899 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03043128 0,11652606 ! glial cell migration GO:0008347 10 5 0,000 0,03043128 0,11634371 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03043128 0,11616192 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03043128 0,1159807 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03043128 0,11580004 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03043128 0,11561995 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03043128 0,11544042 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03043128 0,11526144 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03043128 0,11508302 ! neuroprotection GO:0043526 8 5 0,000 0,03043128 0,11490514 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03043128 0,11472782 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03043128 0,11455105 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03043128 0,11437481 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03043128 0,11419912 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03043128 0,11402397 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03043128 0,11384935 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03043128 0,11367527 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03043128 0,11350172 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03043128 0,1133287 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03043128 0,11315621 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03043128 0,11298424 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03043128 0,11281279 ! spindle assembly GO:0051225 6 5 0,000 0,03043128 0,11264186 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03043128 0,11247145 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03043128 0,11230155 ! protein palmitoylation GO:0018345 12 5 0,000 0,03043128 0,11213217 ! drug metabolic process GO:0017144 7 5 0,000 0,03043128 0,1119633 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03043128 0,11179493 ! organ regeneration GO:0031100 7 5 0,000 0,03043128 0,11162707 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03043128 0,11145971 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03043128 0,11129286 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,03145168 0,11485271 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,03145168 0,11468129 ! biopolymer methylation GO:0043414 91 45 1,000 0,03145168 0,11451038 ! B cell differentiation GO:0030183 124 45 1,000 0,03145168 0,11433997 ! developmental growth GO:0048589 88 45 1,000 0,03145168 0,11417008 ! maintenance of location in cell GO:0051651 101 45 1,000 0,03145168 0,11400069 ! activation of adenylate cyclase activity GO:0007190 94 46 1,000 0,03275034 0,11853198 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 0,03540959 0,12796691 ! mitochondrial transport GO:0006839 94 48 1,000 0,03540959 0,12777789 ! cellular component disassembly GO:0022411 89 48 1,000 0,03540959 0,12758942 ! endosome transport GO:0016197 127 48 1,000 0,03540959 0,12740152 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,03540959 0,12721416 ! male sex differentiation GO:0046661 93 48 1,000 0,03540959 0,12702736 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,03540959 0,1268411 ! methylation GO:0032259 97 48 1,000 0,03540959 0,12665539 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,036406 0,13002905 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,036406 0,12983922 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,036406 0,12964995 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,036406 0,12946123 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,036406 0,12927306 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,036406 0,12908544 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,036406 0,12889836 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,036406 0,12871182 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,036406 0,12852582 ! response to oxygen radical GO:0000305 11 6 0,000 0,036406 0,12834036 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,036406 0,12815543 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,036406 0,12797103 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,036406 0,12778717 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,036406 0,12760383 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,036406 0,12742101 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,036406 0,12723872 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,036406 0,12705695 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,036406 0,1268757 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,036406 0,12669497 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,036406 0,12651475 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,036406 0,12633504 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,036406 0,12615584 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,036406 0,12597715 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,036406 0,12579896 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,036406 0,12562128 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,036406 0,1254441 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,036406 0,12526742 ! malate metabolic process GO:0006108 13 6 0,000 0,036406 0,12509123 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,036406 0,12491554 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,036406 0,12474035 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,036406 0,12456564 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,036406 0,12439142 ! protein refolding GO:0042026 15 6 0,000 0,036406 0,12421769 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,036406 0,12404445 ! opsonization GO:0008228 8 6 0,000 0,036406 0,12387168 ! mating behavior GO:0007617 7 6 0,000 0,036406 0,1236994 ! erythrocyte maturation GO:0043249 8 6 0,000 0,036406 0,12352759 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,036406 0,12335627 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,036406 0,12318541 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,036406 0,12301503 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,036406 0,12284512 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,036406 0,12267568 ! response to interferon-gamma GO:0034341 16 6 0,000 0,036406 0,1225067 ! toxin metabolic process GO:0009404 11 6 0,000 0,036406 0,12233819 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,036406 0,12217015 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,036406 0,12200256 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,036406 0,12183543 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,036406 0,12166877 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,036406 0,12150255 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,036406 0,12133679 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,036406 0,12117148 ! thymic T cell selection GO:0045061 16 6 0,000 0,036406 0,12100662 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,036406 0,12084221 ! protein lipoylation GO:0009249 10 6 0,000 0,036406 0,12067825 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,036406 0,12051473 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,036406 0,12035165 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,036406 0,12018901 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,036406 0,12002681 ! glutamate catabolic process GO:0006538 12 6 0,000 0,036406 0,11986505 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,036406 0,11970372 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,036406 0,11954283 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,036406 0,11938237 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,036406 0,11922234 ! hyperosmotic response GO:0006972 10 6 0,000 0,036406 0,11906274 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,036406 0,11890357 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,036406 0,11874482 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,036406 0,11858649 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,036406 0,11842859 ! urea metabolic process GO:0019627 7 6 0,000 0,036406 0,1182711 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,036406 0,11811403 ! neutrophil activation GO:0042119 7 6 0,000 0,036406 0,11795738 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,036406 0,11780115 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,036406 0,11764533 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,036406 0,11748992 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,036406 0,11733492 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,036406 0,11718033 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,036406 0,11702614 ! neuron apoptosis GO:0051402 15 6 0,000 0,036406 0,11687236 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,036406 0,11671899 ! T cell mediated immunity GO:0002456 17 6 0,000 0,036406 0,11656601 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,036406 0,11641344 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,036406 0,11626126 ! carnitine transport GO:0015879 10 6 0,000 0,036406 0,11610949 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,036406 0,11595811 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,036406 0,11580712 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,036406 0,11565652 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,036406 0,11550632 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,036406 0,11535651 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,036406 0,11520708 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,036406 0,11505804 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,036406 0,11490939 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,036406 0,11476112 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,036406 0,11461323 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,036406 0,11446572 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,036406 0,1143186 ! astrocyte development GO:0014002 16 6 0,000 0,036406 0,11417185 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,036406 0,11402547 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,036406 0,11387947 ! interaction with symbiont GO:0051702 14 6 0,000 0,036406 0,11373385 ! regulation of dendrite development GO:0050773 16 6 0,000 0,036406 0,11358859 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,036406 0,11344371 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,036406 0,11329919 ! response to copper ion GO:0046688 10 6 0,000 0,036406 0,11315505 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,036406 0,11301127 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,036406 0,11286785 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,036406 0,1127248 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,036406 0,11258211 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,036406 0,11243978 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,036406 0,11229781 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,036406 0,1121562 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,036406 0,11201495 ! hair follicle maturation GO:0048820 8 6 0,000 0,036406 0,11187405 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,036406 0,1117335 ! Schwann cell development GO:0014044 15 6 0,000 0,036406 0,11159331 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,036406 0,11145347 ! response to pheromone GO:0019236 6 6 0,000 0,036406 0,11131398 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,036406 0,11117483 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,036406 0,11103604 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,036406 0,11089759 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,036406 0,11075949 ! subpallium development GO:0021544 15 6 0,000 0,036406 0,11062173 ! neural tube patterning GO:0021532 8 6 0,000 0,036406 0,11048431 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,036406 0,11034723 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,036406 0,11021049 ! maintenance of organ identity GO:0048496 9 6 0,000 0,036406 0,11007409 ! G2 phase GO:0051319 16 6 0,000 0,036406 0,10993803 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,036406 0,10980231 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,036406 0,10966691 ! oxygen homeostasis GO:0032364 10 6 0,000 0,036406 0,10953186 ! establishment of planar polarity GO:0001736 7 6 0,000 0,036406 0,10939713 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,036406 0,10926274 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,036406 0,10912867 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,036406 0,10899494 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,036406 0,10886153 ! receptor internalization GO:0031623 11 6 0,000 0,036406 0,10872844 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,036406 0,10859569 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,036406 0,10846325 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,036406 0,10833114 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,036406 0,10819935 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,036406 0,10806788 ! protein deubiquitination GO:0016579 16 6 0,000 0,036406 0,10793673 ! protein destabilization GO:0031648 9 6 0,000 0,036406 0,1078059 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,036406 0,10767538 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,036406 0,10754518 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,036406 0,1074153 ! regulation of viral transcription GO:0046782 11 6 0,000 0,036406 0,10728573 ! progesterone metabolic process GO:0042448 12 6 0,000 0,036406 0,10715647 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,036406 0,10702752 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,036406 0,10689888 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,036406 0,10677055 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,036406 0,10664253 ! determination of adult lifespan GO:0008340 17 6 0,000 0,036406 0,10651481 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,036406 0,1063874 ! neural plate development GO:0001840 9 6 0,000 0,036406 0,1062603 ! catecholamine transport GO:0051937 9 6 0,000 0,036406 0,10613349 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,036406 0,10600699 ! sensory cilium assembly GO:0035058 10 6 0,000 0,036406 0,10588079 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,036406 0,1057549 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,036406 0,1056293 ! maternal placenta development GO:0001893 12 6 0,000 0,036406 0,10550399 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,036406 0,10537899 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,036406 0,10525428 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,036406 0,10512987 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,036406 0,10500575 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,036406 0,10488192 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,036406 0,10475838 GO:0055081|anion homeostasis, ! positive regulation of cyclase activity GO:0031281 106 49 1,000 0,03676958 0,10568009 ! regulation of action potential GO:0001508 102 50 1,000 0,03814941 0,10951705 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,03814941 0,10938851 ! positive regulation of lyase activity GO:0051349 107 50 1,000 0,03814941 0,10926027 ! viral infectious cycle GO:0019058 104 51 1,000 0,03954879 0,11313549 ! positive regulation of binding GO:0051099 88 52 1,000 0,04096744 0,11705667 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,04096744 0,11691992 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,04096744 0,11678349 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,04096744 0,11664738 ! tRNA transcription GO:0009304 17 7 0,000 0,04234407 0,12042674 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04234407 0,12028671 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04234407 0,120147 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04234407 0,12000762 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,04234407 0,11986856 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04234407 0,11972983 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04234407 0,11959141 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04234407 0,11945331 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04234407 0,11931554 ! prostate gland development GO:0030850 14 7 0,000 0,04234407 0,11917808 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04234407 0,11904093 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04234407 0,1189041 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04234407 0,11876759 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04234407 0,11863139 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04234407 0,1184955 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04234407 0,11835992 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04234407 0,11822465 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04234407 0,11808969 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04234407 0,11795504 ! glycolipid transport GO:0046836 11 7 0,000 0,04234407 0,11782069 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04234407 0,11768665 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,04234407 0,11755292 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04234407 0,11741949 ! mRNA stabilization GO:0048255 18 7 0,000 0,04234407 0,11728636 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04234407 0,11715353 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04234407 0,11702101 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04234407 0,11688878 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,04234407 0,11675685 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04234407 0,11662522 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04234407 0,11649388 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04234407 0,11636285 ! lipoprotein transport GO:0042953 14 7 0,000 0,04234407 0,1162321 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04234407 0,11610165 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04234407 0,11597149 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04234407 0,11584162 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04234407 0,11571205 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04234407 0,11558276 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04234407 0,11545376 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04234407 0,11532505 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04234407 0,11519663 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04234407 0,11506849 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04234407 0,11494063 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04234407 0,11481306 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04234407 0,11468578 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04234407 0,11455877 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04234407 0,11443205 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04234407 0,1143056 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04234407 0,11417944 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04234407 0,11405355 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04234407 0,11392794 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04234407 0,11380261 ! adrenal gland development GO:0030325 17 7 0,000 0,04234407 0,11367755 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04234407 0,11355277 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04234407 0,11342826 ! ovulation GO:0030728 10 7 0,000 0,04234407 0,11330402 ! adenohypophysis development GO:0021984 11 7 0,000 0,04234407 0,11318005 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04234407 0,11305636 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04234407 0,11293294 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04234407 0,11280978 ! microtubule nucleation GO:0007020 21 7 0,000 0,04234407 0,11268689 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04234407 0,11256428 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04234407 0,11244192 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04234407 0,11231984 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04234407 0,11219801 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04234407 0,11207646 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04234407 0,11195516 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04234407 0,11183413 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04234407 0,11171336 ! galactose metabolic process GO:0006012 13 7 0,000 0,04234407 0,11159285 ! vesicle fusion GO:0006906 20 7 0,000 0,04234407 0,1114726 ! response to dietary excess GO:0002021 8 7 0,000 0,04234407 0,1113526 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04234407 0,11123287 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04234407 0,11111339 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04234407 0,11099417 ! nucleoside transport GO:0015858 11 7 0,000 0,04234407 0,11087521 ! nucleoside salvage GO:0043174 11 7 0,000 0,04234407 0,1107565 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04234407 0,11063804 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04234407 0,11051984 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04234407 0,11040189 ! parturition GO:0007567 16 7 0,000 0,04234407 0,11028419 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,04234407 0,11016674 ! rRNA modification GO:0000154 14 7 0,000 0,04234407 0,11004954 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04234407 0,10993259 ! spindle checkpoint GO:0031577 16 7 0,000 0,04234407 0,10981589 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04234407 0,10969944 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04234407 0,10958323 ! monocyte differentiation GO:0030224 16 7 0,000 0,04234407 0,10946727 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04234407 0,10935155 ! centrosome duplication GO:0051298 14 7 0,000 0,04234407 0,10923608 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04234407 0,10912085 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04234407 0,10900587 ! fibrinolysis GO:0042730 11 7 0,000 0,04234407 0,10889113 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,04234407 0,10877662 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04234407 0,10866236 ! eating behavior GO:0042755 8 7 0,000 0,04234407 0,10854834 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04234407 0,10843456 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04234407 0,10832101 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04234407 0,10820771 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04234407 0,10809464 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04234407 0,10798181 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04234407 0,10786921 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04234407 0,10775684 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04234407 0,10764471 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04234407 0,10753282 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04234407 0,10742115 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04234407 0,10730972 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04234407 0,10719852 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04234407 0,10708755 ! histone ubiquitination GO:0016574 9 7 0,000 0,04234407 0,1069768 ! regulation of meiosis GO:0040020 12 7 0,000 0,04234407 0,10686629 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04234407 0,10675601 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04234407 0,10664595 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04234407 0,10653612 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04234407 0,10642651 ! transcription termination GO:0006353 14 7 0,000 0,04234407 0,10631713 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04234407 0,10620798 ! anaphase GO:0051322 18 7 0,000 0,04234407 0,10609905 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04234407 0,10599034 ! axonal fasciculation GO:0007413 19 7 0,000 0,04234407 0,10588185 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04234407 0,10577359 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04234407 0,10566555 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04234407 0,10555772 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04234407 0,10545012 ! diuresis GO:0030146 12 7 0,000 0,04234407 0,10534274 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04234407 0,10523557 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04234407 0,10512863 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04234407 0,1050219 ! antibiotic transport GO:0042891 9 7 0,000 0,04234407 0,10491538 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04234407 0,10480909 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04234407 0,10470301 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04234407 0,10459714 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04234407 0,10449148 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04234407 0,10438604 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04234407 0,10428082 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04234407 0,1041758 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04234407 0,104071 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04234407 0,1039664 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04234407 0,10386202 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04234407 0,10375784 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04234407 0,10365388 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04234407 0,10355012 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04234407 0,10344657 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04234407 0,10334323 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04234407 0,10324009 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04234407 0,10313716 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04234407 0,10303443 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04234407 0,10293191 ! muscle adaptation GO:0043500 13 7 0,000 0,04234407 0,10282959 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04234407 0,10272748 ! retina homeostasis GO:0001895 12 7 0,000 0,04234407 0,10262556 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04234407 0,10252385 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04234407 0,10242235 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04234407 0,10232104 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04234407 0,10221993 ! chromatin remodeling GO:0006338 122 53 1,000 0,04240506 0,1022661 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,04240506 0,10216524 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,04240506 0,10206459 ! synapse organization GO:0050808 102 53 1,000 0,04240506 0,10196413 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,04386136 0,10536215 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,04533607 0,10879767 ! cell maturation GO:0048469 107 55 1,000 0,04533607 0,1086909 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,04682891 0,11215983 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,04682891 0,11204998 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04824571 0,11532708 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04824571 0,11521435 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04824571 0,11510184 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04824571 0,11498954 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04824571 0,11487747 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04824571 0,11476561 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04824571 0,11465397 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04824571 0,11454255 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04824571 0,11443134 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04824571 0,11432035 ! meiotic prophase I GO:0007128 14 8 0,000 0,04824571 0,11420957 ! response to zinc ion GO:0010043 12 8 0,000 0,04824571 0,11409901 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04824571 0,11398867 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04824571 0,11387853 ! oligopeptide transport GO:0006857 16 8 0,000 0,04824571 0,11376861 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04824571 0,1136589 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04824571 0,1135494 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04824571 0,11344012 ! signal peptide processing GO:0006465 12 8 0,000 0,04824571 0,11333104 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04824571 0,11322217 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04824571 0,11311351 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04824571 0,11300506 ! succinate metabolic process GO:0006105 17 8 0,000 0,04824571 0,11289682 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04824571 0,11278879 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04824571 0,11268096 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04824571 0,11257333 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04824571 0,11246592 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04824571 0,1123587 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04824571 0,1122517 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04824571 0,11214489 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04824571 0,11203829 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04824571 0,11193189 ! reflex GO:0060004 17 8 0,000 0,04824571 0,11182569 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04824571 0,1117197 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04824571 0,1116139 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04824571 0,11150831 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04824571 0,11140291 ! pigment granule organization GO:0048753 17 8 0,000 0,04824571 0,11129772 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04824571 0,11119272 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04824571 0,11108792 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04824571 0,11098331 ! histidine catabolic process GO:0006548 10 8 0,000 0,04824571 0,11087891 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04824571 0,1107747 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04824571 0,11067069 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04824571 0,11056687 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04824571 0,11046324 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04824571 0,11035981 ! melanin metabolic process GO:0006582 17 8 0,000 0,04824571 0,11025658 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04824571 0,11015353 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04824571 0,11005068 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04824571 0,10994802 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04824571 0,10984555 ! macrophage activation GO:0042116 13 8 0,000 0,04824571 0,10974328 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04824571 0,10964119 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04824571 0,10953929 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04824571 0,10943759 ! purine salvage GO:0043101 12 8 0,000 0,04824571 0,10933607 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04824571 0,10923474 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04824571 0,10913359 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04824571 0,10903264 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04824571 0,10893187 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04824571 0,10883128 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04824571 0,10873089 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04824571 0,10863067 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04824571 0,10853064 ! response to UV-B GO:0010224 17 8 0,000 0,04824571 0,1084308 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04824571 0,10833114 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04824571 0,10823166 ! intermediate filament organization GO:0045109 12 8 0,000 0,04824571 0,10813237 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04824571 0,10803325 ! cellular extravasation GO:0045123 13 8 0,000 0,04824571 0,10793432 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04824571 0,10783557 ! response to antibiotic GO:0046677 11 8 0,000 0,04824571 0,107737 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04824571 0,10763861 ! response to tropane GO:0014073 15 8 0,000 0,04824571 0,1075404 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04824571 0,10744237 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04824571 0,10734452 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04824571 0,10724684 ! mast cell activation GO:0045576 14 8 0,000 0,04824571 0,10714935 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04824571 0,10705203 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04824571 0,10695488 ! gas homeostasis GO:0033483 14 8 0,000 0,04824571 0,10685792 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04824571 0,10676112 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04824571 0,10666451 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04824571 0,10656807 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04824571 0,1064718 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04824571 0,1063757 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04824571 0,10627978 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04824571 0,10618404 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04824571 0,10608846 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04824571 0,10599306 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04824571 0,10589783 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04824571 0,10580277 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04824571 0,10570787 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04824571 0,10561315 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04824571 0,1055186 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04824571 0,10542422 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04824571 0,10533001 ! hormone catabolic process GO:0042447 17 8 0,000 0,04824571 0,10523596 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04824571 0,10514209 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04824571 0,10504838 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04824571 0,10495484 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04824571 0,10486146 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04824571 0,10476825 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04824571 0,1046752 ! adult feeding behavior GO:0008343 10 8 0,000 0,04824571 0,10458233 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04824571 0,10448961 ! ATP catabolic process GO:0006200 11 8 0,000 0,04824571 0,10439706 ! blastocyst growth GO:0001832 19 8 0,000 0,04824571 0,10430467 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04824571 0,10421245 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04824571 0,10412039 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04824571 0,10402849 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04824571 0,10393676 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04824571 0,10384518 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04824571 0,10375377 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04824571 0,10366252 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04824571 0,10357142 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04824571 0,10348049 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04824571 0,10338972 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04824571 0,10329911 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04824571 0,10320865 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04824571 0,10311836 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04824571 0,10302822 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04824571 0,10293824 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04824571 0,10284841 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04824571 0,10275874 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04824571 0,10266923 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04824571 0,10257988 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,04833959 0,10269011 ! muscle fiber development GO:0048747 131 57 1,000 0,04833959 0,10260089 ! heart morphogenesis GO:0003007 105 57 1,000 0,04833959 0,10251183 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,04986785 0,10566102 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04986785 0,10556946 ! maintenance of location GO:0051235 124 58 1,000 0,04986785 0,10547806 ! nuclear export GO:0051168 110 59 1,000 0,05141341 0,10865308 ! establishment of organelle localization GO:0051656 122 59 1,000 0,05141341 0,10855917 ! axon extension GO:0048675 16 9 0,000 0,05411115 0,11415677 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05411115 0,11405828 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05411115 0,11395995 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05411115 0,1138618 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05411115 0,11376381 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05411115 0,11366599 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05411115 0,11356834 ! reproductive behavior GO:0019098 22 9 0,000 0,05411115 0,11347085 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05411115 0,11337354 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05411115 0,11327639 ! UTP metabolic process GO:0046051 10 9 0,000 0,05411115 0,1131794 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05411115 0,11308259 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,05411115 0,11298594 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05411115 0,11288945 ! artery development GO:0060840 25 9 0,000 0,05411115 0,11279313 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05411115 0,11269697 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05411115 0,11260097 ! equilibrioception GO:0050957 20 9 0,000 0,05411115 0,11250514 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05411115 0,11240948 ! chemosensory behavior GO:0007635 21 9 0,000 0,05411115 0,11231397 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05411115 0,11221863 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05411115 0,11212345 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05411115 0,11202843 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05411115 0,11193357 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05411115 0,11183887 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05411115 0,11174433 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05411115 0,11164995 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05411115 0,11155573 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05411115 0,11146167 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05411115 0,11136777 ! protein targeting to ER GO:0045047 25 9 0,000 0,05411115 0,11127403 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05411115 0,11118044 ! T cell selection GO:0045058 27 9 0,000 0,05411115 0,11108701 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05411115 0,11099374 ! glycine catabolic process GO:0006546 15 9 0,000 0,05411115 0,11090062 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05411115 0,11080767 ! endosome organization GO:0007032 20 9 0,000 0,05411115 0,11071486 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05411115 0,11062221 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05411115 0,11052972 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05411115 0,11043738 ! mannose metabolic process GO:0006013 13 9 0,000 0,05411115 0,1103452 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05411115 0,11025316 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05411115 0,11016129 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05411115 0,11006956 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05411115 0,10997799 ! receptor clustering GO:0043113 20 9 0,000 0,05411115 0,10988657 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05411115 0,1097953 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05411115 0,10970419 ! retinol metabolic process GO:0042572 20 9 0,000 0,05411115 0,10961322 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05411115 0,10952241 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05411115 0,10943174 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05411115 0,10934123 ! macrophage differentiation GO:0030225 15 9 0,000 0,05411115 0,10925086 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05411115 0,10916065 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05411115 0,10907058 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05411115 0,10898066 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05411115 0,10889089 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05411115 0,10880127 ! response to amine stimulus GO:0014075 13 9 0,000 0,05411115 0,1087118 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05411115 0,10862247 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05411115 0,10853329 ! erythrocyte development GO:0048821 17 9 0,000 0,05411115 0,10844425 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05411115 0,10835536 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05411115 0,10826662 ! renal water homeostasis GO:0003091 15 9 0,000 0,05411115 0,10817802 ! postreplication repair GO:0006301 25 9 0,000 0,05411115 0,10808957 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05411115 0,10800126 ! icosanoid secretion GO:0032309 15 9 0,000 0,05411115 0,1079131 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05411115 0,10782508 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05411115 0,1077372 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05411115 0,10764947 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05411115 0,10756188 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05411115 0,10747443 ! sterol catabolic process GO:0016127 14 9 0,000 0,05411115 0,10738712 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05411115 0,10729995 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05411115 0,10721293 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05411115 0,10712605 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05411115 0,10703931 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05411115 0,10695271 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05411115 0,10686624 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05411115 0,10677992 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05411115 0,10669374 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05411115 0,1066077 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05411115 0,10652179 ! purine base metabolic process GO:0006144 25 9 0,000 0,05411115 0,10643603 ! pigment granule transport GO:0051904 17 9 0,000 0,05411115 0,1063504 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,05411115 0,10626491 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05411115 0,10617955 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05411115 0,10609434 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05411115 0,10600926 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05411115 0,10592431 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05411115 0,10583951 ! mitochondrion localization GO:0051646 18 9 0,000 0,05411115 0,10575484 ! camera-type eye development GO:0043010 126 61 1,000 0,05455536 0,10653777 ! mesoderm development GO:0007498 128 63 1,000 0,05776333 0,11271231 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05994061 0,11686744 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05994061 0,11677424 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05994061 0,1166812 ! associative learning GO:0008306 21 10 0,000 0,05994061 0,1165883 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05994061 0,11649555 ! phosphate transport GO:0006817 24 10 0,000 0,05994061 0,11640294 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05994061 0,11631049 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05994061 0,11621818 ! CTP metabolic process GO:0046036 11 10 0,000 0,05994061 0,11612601 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05994061 0,11603399 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05994061 0,11594212 ! GTP metabolic process GO:0046039 11 10 0,000 0,05994061 0,1158504 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05994061 0,11575882 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05994061 0,11566738 ! social behavior GO:0035176 29 10 0,000 0,05994061 0,11557609 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05994061 0,11548494 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05994061 0,11539393 ! androgen metabolic process GO:0008209 17 10 0,000 0,05994061 0,11530307 ! phospholipid efflux GO:0033700 19 10 0,000 0,05994061 0,11521235 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05994061 0,11512178 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05994061 0,11503134 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05994061 0,11494105 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05994061 0,1148509 ! pathogenesis GO:0009405 17 10 0,000 0,05994061 0,11476089 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05994061 0,11467103 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05994061 0,1145813 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05994061 0,11449171 ! endoderm development GO:0007492 18 10 0,000 0,05994061 0,11440227 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05994061 0,11431296 ! arginine catabolic process GO:0006527 17 10 0,000 0,05994061 0,11422379 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05994061 0,11413476 ! proline metabolic process GO:0006560 13 10 0,000 0,05994061 0,11404587 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05994061 0,11395712 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05994061 0,11386851 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05994061 0,11378003 ! V(D)J recombination GO:0033151 34 10 0,000 0,05994061 0,11369169 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05994061 0,11360349 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05994061 0,11351543 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05994061 0,1134275 ! B cell proliferation GO:0042100 19 10 0,000 0,05994061 0,11333971 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05994061 0,11325205 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05994061 0,11316453 ! multicellular organism growth GO:0035264 19 10 0,000 0,05994061 0,11307714 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05994061 0,11298989 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05994061 0,11290278 ! ruffle organization GO:0031529 17 10 0,000 0,05994061 0,11281579 ! epithelial cell development GO:0002064 21 10 0,000 0,05994061 0,11272895 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05994061 0,11264223 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05994061 0,11255565 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05994061 0,1124692 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05994061 0,11238289 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05994061 0,1122967 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05994061 0,11221065 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,05994061 0,11212473 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05994061 0,11203895 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05994061 0,11195329 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05994061 0,11186776 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05994061 0,11178237 ! segment specification GO:0007379 15 10 0,000 0,05994061 0,1116971 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05994061 0,11161197 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05994061 0,11152696 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05994061 0,11144209 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05994061 0,11135734 ! response to dsRNA GO:0043331 23 10 0,000 0,05994061 0,11127272 ! DNA ligation GO:0006266 18 10 0,000 0,05994061 0,11118823 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05994061 0,11110387 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05994061 0,11101964 ! melanosome localization GO:0032400 16 10 0,000 0,05994061 0,11093553 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05994061 0,11085155 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05994061 0,1107677 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05994061 0,11068398 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05994061 0,11060038 ! induction of an organ GO:0001759 17 10 0,000 0,05994061 0,11051691 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05994061 0,11043356 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05994061 0,11035034 ! protein sumoylation GO:0016925 17 10 0,000 0,05994061 0,11026724 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05994061 0,11018427 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05994061 0,11010143 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05994061 0,11001871 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05994061 0,10993611 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05994061 0,10985364 ! salivary gland development GO:0007431 28 10 0,000 0,05994061 0,10977129 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05994061 0,10968906 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05994061 0,10960696 ! midbrain development GO:0030901 14 10 0,000 0,05994061 0,10952498 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05994061 0,10944312 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05994061 0,10936139 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05994061 0,10927978 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05994061 0,10919829 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05994061 0,10911692 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05994061 0,10903567 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05994061 0,10895454 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05994061 0,10887353 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05994061 0,10879265 ! detection of calcium ion GO:0005513 24 10 0,000 0,05994061 0,10871188 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05994061 0,10863123 ! blastocyst formation GO:0001825 18 10 0,000 0,05994061 0,10855071 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05994061 0,1084703 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05994061 0,10839001 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05994061 0,10830984 ! response to nicotine GO:0035094 20 10 0,000 0,05994061 0,10822979 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05994061 0,10814985 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05994061 0,10807004 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,06103523 0,10996244 ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,06103523 0,10988141 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,06269452 0,1127855 ! chromosome segregation GO:0007059 127 67 1,000 0,06436903 0,11571269 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,06436903 0,11562761 ! respiratory burst GO:0045730 17 11 0,000 0,0657343 0,1179933 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0657343 0,11790667 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0657343 0,11782017 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0657343 0,11773379 ! thyroid gland development GO:0030878 26 11 0,000 0,0657343 0,11764754 ! synapsis GO:0007129 14 11 0,000 0,0657343 0,11756141 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0657343 0,11747541 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0657343 0,11738954 ! response to pain GO:0048265 27 11 0,000 0,0657343 0,11730379 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0657343 0,11721817 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0657343 0,11713267 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0657343 0,11704729 ! bone resorption GO:0045453 16 11 0,000 0,0657343 0,11696204 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0657343 0,11687692 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0657343 0,11679192 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0657343 0,11670704 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0657343 0,11662229 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0657343 0,11653765 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0657343 0,11645315 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0657343 0,11636876 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0657343 0,1162845 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0657343 0,11620035 ! adult heart development GO:0007512 16 11 0,000 0,0657343 0,11611633 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0657343 0,11603243 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0657343 0,11594866 ! macroautophagy GO:0016236 19 11 0,000 0,0657343 0,115865 ! temperature homeostasis GO:0001659 18 11 0,000 0,0657343 0,11578146 ! behavioral fear response GO:0001662 27 11 0,000 0,0657343 0,11569805 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0657343 0,11561475 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0657343 0,11553157 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0657343 0,11544852 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0657343 0,11536558 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0657343 0,11528276 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0657343 0,11520006 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0657343 0,11511748 ! regulation of organ growth GO:0046620 14 11 0,000 0,0657343 0,11503502 ! pigment granule localization GO:0051875 20 11 0,000 0,0657343 0,11495268 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0657343 0,11487045 ! vasoconstriction GO:0042310 20 11 0,000 0,0657343 0,11478834 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0657343 0,11470635 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0657343 0,11462447 ! embryonic axis specification GO:0000578 19 11 0,000 0,0657343 0,11454272 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0657343 0,11446107 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0657343 0,11437955 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0657343 0,11429814 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0657343 0,11421685 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0657343 0,11413567 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0657343 0,11405461 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0657343 0,11397366 ! prophase GO:0051324 17 11 0,000 0,0657343 0,11389283 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0657343 0,11381211 ! nucleosome positioning GO:0016584 15 11 0,000 0,0657343 0,11373151 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0657343 0,11365102 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0657343 0,11357064 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0657343 0,11349038 ! apical protein localization GO:0045176 18 11 0,000 0,0657343 0,11341023 ! acid secretion GO:0046717 20 11 0,000 0,0657343 0,1133302 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0657343 0,11325027 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0657343 0,11317046 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0657343 0,11309077 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0657343 0,11301118 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0657343 0,11293171 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0657343 0,11285235 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0657343 0,1127731 ! cholesterol efflux GO:0033344 21 11 0,000 0,0657343 0,11269396 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0657343 0,11261493 ! oocyte development GO:0048599 20 11 0,000 0,0657343 0,11253601 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0657343 0,1124572 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0657343 0,11237851 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0657343 0,11229992 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0657343 0,11222144 ! activation of innate immune response GO:0002218 16 11 0,000 0,0657343 0,11214308 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0657343 0,11206482 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0657343 0,11198667 ! lysogeny GO:0030069 22 11 0,000 0,0657343 0,11190863 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0657343 0,1118307 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0657343 0,11175288 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0657343 0,11167517 ! nucleus localization GO:0051647 22 11 0,000 0,0657343 0,11159756 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,06605852 0,11207011 ! extracellular matrix organization GO:0030198 146 68 1,000 0,06605852 0,11199233 ! regulation of lipase activity GO:0060191 137 68 1,000 0,06605852 0,11191467 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,06605852 0,11183711 ! cell projection assembly GO:0030031 138 68 1,000 0,06605852 0,11175966 ! developmental maturation GO:0021700 128 69 1,000 0,06776273 0,11456356 ! cell redox homeostasis GO:0045454 114 70 1,000 0,06948142 0,11738805 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,07121436 0,12023268 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,07121436 0,12014965 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,07149244 0,12053557 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07149244 0,12045244 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,07149244 0,12036943 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,07149244 0,12028653 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07149244 0,12020374 ! protein complex disassembly GO:0043241 28 12 0,000 0,07149244 0,12012107 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07149244 0,12003851 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,07149244 0,11995607 ! hippocampus development GO:0021766 29 12 0,000 0,07149244 0,11987374 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,07149244 0,11979152 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07149244 0,11970942 ! T cell proliferation GO:0042098 32 12 0,000 0,07149244 0,11962742 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07149244 0,11954554 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07149244 0,11946377 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07149244 0,11938212 ! drug transport GO:0015893 16 12 0,000 0,07149244 0,11930057 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,07149244 0,11921914 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,07149244 0,11913782 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07149244 0,1190566 ! polyamine metabolic process GO:0006595 18 12 0,000 0,07149244 0,1189755 ! focal adhesion formation GO:0048041 37 12 0,000 0,07149244 0,11889451 ! mitotic spindle organization GO:0007052 23 12 0,000 0,07149244 0,11881363 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07149244 0,11873286 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,07149244 0,1186522 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,07149244 0,11857165 ! lipid digestion GO:0044241 21 12 0,000 0,07149244 0,11849121 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07149244 0,11841087 ! entry into host cell GO:0030260 34 12 0,000 0,07149244 0,11833065 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07149244 0,11825053 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07149244 0,11817053 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07149244 0,11809063 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07149244 0,11801084 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07149244 0,11793115 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,07149244 0,11785158 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07149244 0,11777211 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07149244 0,11769275 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07149244 0,11761349 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07149244 0,11753435 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07149244 0,1174553 ! fucose catabolic process GO:0019317 25 12 0,000 0,07149244 0,11737637 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,07149244 0,11729754 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,07149244 0,11721882 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,07149244 0,1171402 ! zymogen activation GO:0031638 18 12 0,000 0,07149244 0,11706169 ! T cell homeostasis GO:0043029 28 12 0,000 0,07149244 0,11698328 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07149244 0,11690498 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07149244 0,11682678 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,07149244 0,11674869 ! oocyte differentiation GO:0009994 21 12 0,000 0,07149244 0,1166707 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,07149244 0,11659282 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07149244 0,11651504 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,07149244 0,11643736 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,07149244 0,11635979 ! defense response to fungus GO:0050832 15 12 0,000 0,07149244 0,11628232 ! developmental induction GO:0031128 22 12 0,000 0,07149244 0,11620495 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,07149244 0,11612768 ! lamellipodium assembly GO:0030032 24 12 0,000 0,07149244 0,11605052 ! response to cold GO:0009409 17 12 0,000 0,07149244 0,11597346 ! establishment of cell polarity GO:0030010 21 12 0,000 0,07149244 0,11589651 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07149244 0,11581965 ! B cell activation GO:0042113 179 72 1,000 0,0729613 0,11812092 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,0729613 0,11804269 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,07649626 0,12367992 ! organelle localization GO:0051640 155 74 1,000 0,07649626 0,12359812 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07721526 0,12467738 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07721526 0,12459503 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07721526 0,12451279 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07721526 0,12443066 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07721526 0,12434864 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07721526 0,12426672 ! peroxisomal transport GO:0043574 28 13 0,000 0,07721526 0,12418491 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07721526 0,12410321 ! cartilage condensation GO:0001502 22 13 0,000 0,07721526 0,12402162 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07721526 0,12394013 ! organelle fusion GO:0048284 36 13 0,000 0,07721526 0,12385875 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07721526 0,12377748 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07721526 0,12369632 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07721526 0,12361526 ! endocrine pancreas development GO:0031018 25 13 0,000 0,07721526 0,1235343 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07721526 0,12345346 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07721526 0,12337271 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07721526 0,12329208 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07721526 0,12321155 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07721526 0,12313112 ! methionine metabolic process GO:0006555 31 13 0,000 0,07721526 0,1230508 ! plasma membrane organization GO:0007009 27 13 0,000 0,07721526 0,12297059 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07721526 0,12289048 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07721526 0,12281047 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07721526 0,12273057 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07721526 0,12265077 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,07721526 0,12257107 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07721526 0,12249148 ! exocrine system development GO:0035272 34 13 0,000 0,07721526 0,12241199 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07721526 0,12233261 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07721526 0,12225333 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07721526 0,12217415 ! L-glutamate transport GO:0015813 30 13 0,000 0,07721526 0,12209507 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07721526 0,12201609 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07721526 0,12193722 ! protein homotetramerization GO:0051289 24 13 0,000 0,07721526 0,12185845 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07721526 0,12177978 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07721526 0,12170121 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07721526 0,12162275 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07721526 0,12154438 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07721526 0,12146612 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07721526 0,12138795 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07721526 0,12130989 ! histone methylation GO:0016571 29 13 0,000 0,07721526 0,12123193 ! chromatin silencing GO:0006342 29 13 0,000 0,07721526 0,12115407 ! gland morphogenesis GO:0022612 31 13 0,000 0,07721526 0,1210763 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07721526 0,12099864 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07721526 0,12092108 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07721526 0,12084361 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07721526 0,12076625 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07721526 0,12068898 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07721526 0,12061182 ! spleen development GO:0048536 24 13 0,000 0,07721526 0,12053475 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,07721526 0,12045778 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07721526 0,12038091 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07721526 0,12030413 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07721526 0,12022746 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07721526 0,12015088 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07721526 0,1200744 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07721526 0,11999802 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07721526 0,11992173 ! insulin secretion GO:0030073 24 13 0,000 0,07721526 0,11984554 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07721526 0,11976945 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,07721526 0,11969345 ! acrosome reaction GO:0007340 19 13 0,000 0,07721526 0,11961755 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07721526 0,11954175 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07721526 0,11946604 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,0782838 0,12104261 ! eye development GO:0001654 155 75 1,000 0,0782838 0,12096605 ! axon guidance GO:0007411 162 75 1,000 0,0782838 0,12088959 ! rhythmic process GO:0048511 142 75 1,000 0,0782838 0,12081322 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,08008442 0,12351404 ! rRNA transcription GO:0009303 28 14 0,000 0,08290297 0,12778041 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08290297 0,12769984 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,08290297 0,12761937 ! water transport GO:0006833 21 14 0,000 0,08290297 0,12753901 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,08290297 0,12745874 ! non-recombinational repair GO:0000726 29 14 0,000 0,08290297 0,12737858 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,08290297 0,12729852 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08290297 0,12721856 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,08290297 0,1271387 ! RNA polyadenylation GO:0043631 32 14 0,000 0,08290297 0,12705894 ! lipid localization GO:0010876 32 14 0,000 0,08290297 0,12697928 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,08290297 0,12689971 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,08290297 0,12682025 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08290297 0,12674089 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08290297 0,12666163 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08290297 0,12658247 ! arginine metabolic process GO:0006525 21 14 0,000 0,08290297 0,1265034 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,08290297 0,12642444 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08290297 0,12634557 ! regulation of heart rate GO:0002027 25 14 0,000 0,08290297 0,1262668 ! fear response GO:0042596 34 14 0,000 0,08290297 0,12618813 ! organic alcohol transport GO:0015850 29 14 0,000 0,08290297 0,12610955 ! embryo implantation GO:0007566 30 14 0,000 0,08290297 0,12603108 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08290297 0,1259527 ! bone mineralization GO:0030282 18 14 0,000 0,08290297 0,12587442 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08290297 0,12579624 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,08290297 0,12571815 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08290297 0,12564016 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,08290297 0,12556227 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08290297 0,12548448 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,08290297 0,12540678 ! ribosome assembly GO:0042255 18 14 0,000 0,08290297 0,12532917 ! cerebellum development GO:0021549 23 14 0,000 0,08290297 0,12525167 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,08290297 0,12517426 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,08290297 0,12509694 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08290297 0,12501972 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08290297 0,12494259 ! NADP metabolic process GO:0006739 24 14 0,000 0,08290297 0,12486556 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,08290297 0,12478863 ! oxygen transport GO:0015671 22 14 0,000 0,08290297 0,12471179 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08290297 0,12463504 ! regulation of RNA stability GO:0043487 33 14 0,000 0,08290297 0,12455839 ! regulation of axon extension GO:0030516 43 14 0,000 0,08290297 0,12448183 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08290297 0,12440537 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,08290297 0,124329 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,08372396 0,12548321 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0874131 0,13093206 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08855577 0,13256235 ! reproductive cellular process GO:0048610 22 15 0,000 0,08855577 0,13248117 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08855577 0,13240009 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08855577 0,13231912 ! superoxide anion generation GO:0042554 22 15 0,000 0,08855577 0,13223824 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08855577 0,13215745 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,08855577 0,13207677 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08855577 0,13199619 ! copper ion transport GO:0006825 22 15 0,000 0,08855577 0,1319157 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08855577 0,13183532 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08855577 0,13175503 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08855577 0,13167483 ! sulfate transport GO:0008272 27 15 0,000 0,08855577 0,13159474 ! response to cAMP GO:0051591 25 15 0,000 0,08855577 0,13151474 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08855577 0,13143484 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08855577 0,13135504 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08855577 0,13127534 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08855577 0,13119573 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08855577 0,13111621 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08855577 0,1310368 ! vesicle coating GO:0006901 38 15 0,000 0,08855577 0,13095748 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08855577 0,13087825 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,08855577 0,13079913 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08855577 0,13072009 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08855577 0,13064116 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08855577 0,13056231 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08855577 0,13048357 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08855577 0,13040491 ! regulation of vasodilation GO:0042312 27 15 0,000 0,08855577 0,13032636 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,08855577 0,1302479 ! histone deacetylation GO:0016575 24 15 0,000 0,08855577 0,13016953 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08855577 0,13009125 ! water homeostasis GO:0030104 28 15 0,000 0,08855577 0,13001307 ! cofactor transport GO:0051181 30 15 0,000 0,08855577 0,12993499 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08855577 0,129857 ! muscle maintenance GO:0046716 26 15 0,000 0,08855577 0,1297791 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08855577 0,12970129 ! intestinal absorption GO:0050892 31 15 0,000 0,08855577 0,12962358 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08855577 0,12954596 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08855577 0,12946843 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08855577 0,129391 ! cell killing GO:0001906 32 15 0,000 0,08855577 0,12931366 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,08855577 0,12923641 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,08855577 0,12915926 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08855577 0,12908219 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08855577 0,12900522 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08855577 0,12892834 ! actin filament polymerization GO:0030041 27 15 0,000 0,08855577 0,12885155 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08855577 0,12877485 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,09303595 0,1352093 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,0941739 0,1367817 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,0941739 0,13670043 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,0941739 0,13661926 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,0941739 0,13653818 ! bone remodeling GO:0046849 28 16 0,000 0,0941739 0,13645719 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,0941739 0,13637631 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,0941739 0,13629551 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0941739 0,13621482 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,0941739 0,13613422 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,0941739 0,13605371 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,0941739 0,1359733 ! startle response GO:0001964 28 16 0,000 0,0941739 0,13589299 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,0941739 0,13581277 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,0941739 0,13573264 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,0941739 0,13565261 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,0941739 0,13557267 ! protein polyubiquitination GO:0000209 41 16 0,000 0,0941739 0,13549283 ! glutamate metabolic process GO:0006536 25 16 0,000 0,0941739 0,13541308 ! pituitary gland development GO:0021983 30 16 0,000 0,0941739 0,13533343 ! response to osmotic stress GO:0006970 27 16 0,000 0,0941739 0,13525387 ! lysosomal transport GO:0007041 31 16 0,000 0,0941739 0,1351744 ! fructose metabolic process GO:0006000 25 16 0,000 0,0941739 0,13509503 ! L-amino acid transport GO:0015807 33 16 0,000 0,0941739 0,13501574 ! stem cell development GO:0048864 46 16 0,000 0,0941739 0,13493656 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0941739 0,13485746 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0941739 0,13477846 ! intermediate filament-based process GO:0045103 36 16 0,000 0,0941739 0,13469955 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,0941739 0,13462073 ! negative regulation of immune response GO:0050777 38 16 0,000 0,0941739 0,134542 ! axon cargo transport GO:0008088 46 16 0,000 0,0941739 0,13446337 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,0941739 0,13438483 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,0941739 0,13430638 ! DNA replication initiation GO:0006270 28 16 0,000 0,0941739 0,13422802 ! neuron recognition GO:0008038 40 16 0,000 0,0941739 0,13414975 ! mRNA splice site selection GO:0006376 44 16 0,000 0,0941739 0,13407158 ! tissue regeneration GO:0042246 27 16 0,000 0,0941739 0,13399349 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,0941739 0,1339155 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,0941739 0,1338376 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,0941739 0,13375978 ! biomineral formation GO:0031214 22 16 0,000 0,0941739 0,13368206 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,0941739 0,13360443 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,0941739 0,13352689 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,0941739 0,13344944 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0941739 0,13337207 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,0941739 0,1332948 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,0941739 0,13321762 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,0941739 0,13314053 ! peptide hormone processing GO:0016486 27 16 0,000 0,0941739 0,13306352 ! T cell activation GO:0042110 189 84 1,000 0,09493316 0,13405879 ! response to nutrient GO:0007584 135 84 1,000 0,09493316 0,13398134 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,09684147 0,13659567 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,09876068 0,13922236 ! regulation of lyase activity GO:0051339 169 86 1,000 0,09876068 0,13914207 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,09876068 0,13906187 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of cell killing GO:0031343 36 17 0,000 0,09975755 0,14038461 ! metencephalon development GO:0022037 32 17 0,000 0,09975755 0,14030379 ! signal complex assembly GO:0007172 47 17 0,000 0,09975755 0,14022306 ! filopodium assembly GO:0046847 42 17 0,000 0,09975755 0,14014243 ! endothelial cell migration GO:0043542 31 17 0,000 0,09975755 0,14006189 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09975755 0,13998144 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09975755 0,13990108 ! glial cell development GO:0021782 28 17 0,000 0,09975755 0,13982082 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09975755 0,13974064 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,09975755 0,13966056 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,09975755 0,13958058 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09975755 0,13950068 ! myoblast differentiation GO:0045445 50 17 0,000 0,09975755 0,13942087 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,09975755 0,13934116 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,09975755 0,13926153 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09975755 0,139182 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09975755 0,13910256 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09975755 0,13902321 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09975755 0,13894395 ! NAD metabolic process GO:0019674 33 17 0,000 0,09975755 0,13886478 ! membrane budding GO:0006900 42 17 0,000 0,09975755 0,1387857 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09975755 0,13870671 ! regulation of protein binding GO:0043393 33 17 0,000 0,09975755 0,13862781 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,09975755 0,138549 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09975755 0,13847028 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09975755 0,13839164 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09975755 0,1383131 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09975755 0,13823465 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,09975755 0,13815628 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09975755 0,13807801 ! steroid catabolic process GO:0006706 34 17 0,000 0,09975755 0,13799982 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09975755 0,13792172 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,09975755 0,13784371 ! gas transport GO:0015669 26 17 0,000 0,09975755 0,13776579 ! organic cation transport GO:0015695 32 17 0,000 0,09975755 0,13768796 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,09975755 0,13761021 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,09975755 0,13753255 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,09975755 0,13745498 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,10263099 0,14133456 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,10458168 0,14393974 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,10530693 0,14485633 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,10530693 0,14477481 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,10530693 0,14469339 ! limbic system development GO:0021761 40 18 0,000 0,10530693 0,14461205 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10530693 0,14453081 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,10530693 0,14444966 ! adult walking behavior GO:0007628 36 18 0,000 0,10530693 0,1443686 ! patterning of blood vessels GO:0001569 43 18 0,000 0,10530693 0,14428763 ! heart looping GO:0001947 34 18 0,000 0,10530693 0,14420675 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,10530693 0,14412596 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,10530693 0,14404526 ! centrosome cycle GO:0007098 26 18 0,000 0,10530693 0,14396466 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,10530693 0,14388414 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,10530693 0,14380371 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,10530693 0,14372337 ! glycine metabolic process GO:0006544 30 18 0,000 0,10530693 0,14364313 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10530693 0,14356297 ! response to retinoic acid GO:0032526 31 18 0,000 0,10530693 0,1434829 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,10530693 0,14340292 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,10530693 0,14332303 ! DNA integration GO:0015074 32 18 0,000 0,10530693 0,14324323 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,10530693 0,14316352 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,10530693 0,14308389 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,10530693 0,14300436 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,10530693 0,14292491 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,10530693 0,14284555 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,10530693 0,14276628 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,10530693 0,1426871 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,10530693 0,142608 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,10530693 0,142529 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,10530693 0,14245008 ! detection of bacterium GO:0016045 22 18 0,000 0,10530693 0,14237124 ! defense response to virus GO:0051607 43 18 0,000 0,10530693 0,1422925 ! microspike assembly GO:0030035 46 18 0,000 0,10530693 0,14221384 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,10530693 0,14213527 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,10654246 0,14372349 ! response to unfolded protein GO:0006986 139 90 1,000 0,10654246 0,14364417 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,10851314 0,14622041 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,11082227 0,14924962 ! positive regulation of translation GO:0045727 31 19 0,000 0,11082227 0,14916738 ! negative regulation of defense response GO:0031348 27 19 0,000 0,11082227 0,14908524 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,11082227 0,14900319 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,11082227 0,14892123 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,11082227 0,14883936 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,11082227 0,14875758 ! inositol metabolic process GO:0006020 33 19 0,000 0,11082227 0,14867589 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11082227 0,14859429 ! memory GO:0007613 34 19 0,000 0,11082227 0,14851278 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,11082227 0,14843136 ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,11082227 0,14835003 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,11082227 0,14826879 ! cerebral cortex development GO:0021987 40 19 0,000 0,11082227 0,14818763 ! pigmentation during development GO:0048066 42 19 0,000 0,11082227 0,14810657 ! response to vitamin A GO:0033189 32 19 0,000 0,11082227 0,14802559 ! heme metabolic process GO:0042168 40 19 0,000 0,11082227 0,1479447 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,11082227 0,1478639 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,11082227 0,14778319 ! response to fungus GO:0009620 26 19 0,000 0,11082227 0,14770256 ! peptide cross-linking GO:0018149 39 19 0,000 0,11082227 0,14762203 ! protein export from nucleus GO:0006611 40 19 0,000 0,11082227 0,14754158 ! heart process GO:0003015 32 19 0,000 0,11082227 0,14746122 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,11082227 0,14738095 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,11082227 0,14730076 ! visual learning GO:0008542 38 19 0,000 0,11082227 0,14722066 ! cellular pigmentation GO:0033059 37 19 0,000 0,11082227 0,14714065 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,11082227 0,14706073 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,11082227 0,14698089 ! vitamin transport GO:0051180 31 19 0,000 0,11082227 0,14690114 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,11082227 0,14682148 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,11082227 0,1467419 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,11082227 0,14666241 ! cilium assembly GO:0042384 38 19 0,000 0,11082227 0,146583 ! peptide hormone secretion GO:0030072 32 19 0,000 0,11082227 0,14650368 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,1124834 0,14861923 GO:0010498|proteasomal protein catabolic process, ! female pregnancy GO:0007565 166 94 1,000 0,11448261 0,15117892 ! regulation of membrane potential GO:0042391 179 94 1,000 0,11448261 0,15109725 ! protein secretion GO:0009306 45 20 0,000 0,11630376 0,15341797 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,11630376 0,15333518 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,11630376 0,15325247 ! positive regulation of ossification GO:0045778 50 20 0,000 0,11630376 0,15316986 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,11630376 0,15308733 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,11630376 0,15300489 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,11630376 0,15292254 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,11630376 0,15284028 ! response to vitamin GO:0033273 36 20 0,000 0,11630376 0,15275811 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,11630376 0,15267602 ! bile acid metabolic process GO:0008206 34 20 0,000 0,11630376 0,15259403 ! response to alkaloid GO:0043279 38 20 0,000 0,11630376 0,15251212 ! retinoid metabolic process GO:0001523 34 20 0,000 0,11630376 0,1524303 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,11630376 0,15234857 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,11630376 0,15226692 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,11630376 0,15218537 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,11630376 0,1521039 ! body fluid secretion GO:0007589 33 20 0,000 0,11630376 0,15202252 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,11630376 0,15194122 ! peptide secretion GO:0002790 38 20 0,000 0,11630376 0,15186001 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,11630376 0,15177889 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,11630376 0,15169785 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,11630376 0,15161691 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,11630376 0,15153604 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,11630376 0,15145527 ! cell-cell junction organization GO:0045216 43 20 0,000 0,11630376 0,15137458 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,11630376 0,15129397 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,11630376 0,15121345 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,11630376 0,15113302 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,11630376 0,15105267 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,11630376 0,15097241 ! regulation of glucose import GO:0046324 30 20 0,000 0,11630376 0,15089224 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,11630376 0,15081214 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,11630376 0,15073214 ! negative regulation of translation GO:0017148 32 20 0,000 0,11630376 0,15065222 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,11630376 0,15057238 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,11649094 0,15073483 ! sex differentiation GO:0007548 171 96 1,000 0,11850821 0,15326392 ! response to protein stimulus GO:0051789 158 96 1,000 0,11850821 0,15318283 ! regulation of cell killing GO:0031341 46 21 0,000 0,12175161 0,15729201 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,12175161 0,15720887 ! hormone secretion GO:0046879 39 21 0,000 0,12175161 0,15712582 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,12175161 0,15704286 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,12175161 0,15695999 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,12175161 0,15687721 ! ovarian follicle development GO:0001541 39 21 0,000 0,12175161 0,15679451 ! smooth muscle contraction GO:0006939 48 21 0,000 0,12175161 0,1567119 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,12175161 0,15662937 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,12175161 0,15654694 ! plasma membrane fusion GO:0045026 33 21 0,000 0,12175161 0,15646459 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,12175161 0,15638233 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,12175161 0,15630015 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,12175161 0,15621806 ! sensory perception of pain GO:0019233 33 21 0,000 0,12175161 0,15613605 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,12175161 0,15605414 ! diencephalon development GO:0021536 36 21 0,000 0,12175161 0,1559723 ! collagen fibril organization GO:0030199 62 21 0,000 0,12175161 0,15589056 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,12175161 0,1558089 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,12175161 0,15572732 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,12175161 0,15564583 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,12175161 0,15556443 ! collagen catabolic process GO:0030574 29 21 0,000 0,12175161 0,15548311 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,12175161 0,15540187 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,12175161 0,15532072 ! actin filament-based movement GO:0030048 47 21 0,000 0,12175161 0,15523966 ! leukocyte differentiation GO:0002521 232 98 1,000 0,12256883 0,15620013 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,12256883 0,15611869 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,12716603 0,16188984 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,12716603 0,16180552 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,12716603 0,16172129 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,12716603 0,16163715 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,12716603 0,1615531 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,12716603 0,16146913 ! microtubule-based transport GO:0010970 59 22 0,000 0,12716603 0,16138525 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,12716603 0,16130146 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,12716603 0,16121775 ! vacuolar transport GO:0007034 41 22 0,000 0,12716603 0,16113413 ! central nervous system neuron development GO:0021954 47 22 0,000 0,12716603 0,1610506 ! fucose metabolic process GO:0006004 44 22 0,000 0,12716603 0,16096715 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,12716603 0,16088379 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,12716603 0,16080052 ! stem cell differentiation GO:0048863 57 22 0,000 0,12716603 0,16071733 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,12716603 0,16063423 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,12716603 0,16055122 ! cytolysis GO:0019835 27 22 0,000 0,12716603 0,16046829 ! renal system process GO:0003014 42 22 0,000 0,12716603 0,16038545 ! vasodilation GO:0042311 40 22 0,000 0,12716603 0,16030269 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,12716603 0,16022001 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,12716603 0,16013743 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,12716603 0,16005492 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,12716603 0,15997251 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,12716603 0,15989017 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,12716603 0,15980793 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,12716603 0,15972576 ! sarcomere organization GO:0045214 32 22 0,000 0,12716603 0,15964368 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,12716603 0,15956169 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,12716603 0,15947978 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,12716603 0,15939795 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,12716603 0,15931621 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,12716603 0,15923455 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,13254722 0,16588773 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,13254722 0,16580279 ! gluconeogenesis GO:0006094 38 23 0,000 0,13254722 0,16571794 ! glycerol metabolic process GO:0006071 40 23 0,000 0,13254722 0,16563317 ! viral genome replication GO:0019079 44 23 0,000 0,13254722 0,16554849 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,13254722 0,1654639 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,13254722 0,16537939 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,13254722 0,16529497 ! regeneration GO:0031099 42 23 0,000 0,13254722 0,16521064 ! axis specification GO:0009798 43 23 0,000 0,13254722 0,16512639 ! visual behavior GO:0007632 46 23 0,000 0,13254722 0,16504223 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,13254722 0,16495815 ! response to ethanol GO:0045471 47 23 0,000 0,13254722 0,16487416 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,13254722 0,16479026 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,13254722 0,16470644 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,13254722 0,1646227 ! peroxisome organization GO:0007031 43 23 0,000 0,13254722 0,16453905 ! lysosome organization GO:0007040 47 23 0,000 0,13254722 0,16445549 ! vesicle targeting GO:0006903 49 23 0,000 0,13254722 0,16437201 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,13254722 0,16428861 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,13254722 0,1642053 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,13254722 0,16412208 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,13254722 0,16403893 ! fatty acid transport GO:0015908 47 23 0,000 0,13254722 0,16395588 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,13254722 0,1638729 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,13254722 0,16379001 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,13254722 0,16370721 ! hormone transport GO:0009914 41 23 0,000 0,13254722 0,16362448 ! cell-cell recognition GO:0009988 28 23 0,000 0,13254722 0,16354185 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,13254722 0,16345929 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,13254722 0,16337682 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,13254722 0,16329443 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,13789538 0,16979759 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,13789538 0,16971205 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,13789538 0,1696266 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,13789538 0,16954123 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,13789538 0,16945595 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,13789538 0,16937075 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,13789538 0,16928564 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,13789538 0,16920061 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,13789538 0,16911567 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,13789538 0,16903082 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,13789538 0,16894605 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,13789538 0,16886136 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,13789538 0,16877676 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,13789538 0,16869225 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,13789538 0,16860782 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,13789538 0,16852347 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,13789538 0,16843921 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,13789538 0,16835503 ! membrane depolarization GO:0051899 45 24 0,000 0,13789538 0,16827094 ! pallium development GO:0021543 56 24 0,000 0,13789538 0,16818693 ! oogenesis GO:0048477 44 24 0,000 0,13789538 0,168103 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,13789538 0,16801916 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,13789538 0,1679354 ! platelet activation GO:0030168 41 24 0,000 0,13789538 0,16785173 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,13789538 0,16776814 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,13789538 0,16768463 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,13789538 0,1676012 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,13789538 0,16751786 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,13789538 0,1674346 ! regulation of amine transport GO:0051952 41 24 0,000 0,13789538 0,16735143 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,14321072 0,17371589 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,14321072 0,17362968 ! leukocyte adhesion GO:0007159 55 25 0,000 0,14321072 0,17354355 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,14321072 0,17345751 ! phototransduction GO:0007602 37 25 0,000 0,14321072 0,17337156 ! keratinization GO:0031424 37 25 0,000 0,14321072 0,17328569 ! vasculogenesis GO:0001570 49 25 0,000 0,14321072 0,1731999 ! vacuole organization GO:0007033 49 25 0,000 0,14321072 0,1731142 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,14321072 0,17302859 ! receptor metabolic process GO:0043112 53 25 0,000 0,14321072 0,17294305 ! chromosome condensation GO:0030261 48 25 0,000 0,14321072 0,17285761 ! regulation of behavior GO:0050795 48 25 0,000 0,14321072 0,17277225 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,14321072 0,17268697 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,14321072 0,17260178 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,14321072 0,17251667 ! immunoglobulin production GO:0002377 62 25 0,000 0,14321072 0,17243164 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,14321072 0,1723467 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,14321072 0,17226184 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,14321072 0,17217707 ! liver development GO:0001889 55 25 0,000 0,14321072 0,17209238 ! initiation of viral infection GO:0019059 60 26 0,000 0,14849344 0,17835274 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,14849344 0,1782651 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,14849344 0,17817754 ! molting cycle process GO:0022404 52 26 0,000 0,14849344 0,17809007 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,14849344 0,17800269 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,14849344 0,17791539 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,14849344 0,17782818 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,14849344 0,17774105 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,14849344 0,17765401 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,14849344 0,17756705 ! digestive system process GO:0022600 49 26 0,000 0,14849344 0,17748018 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,14849344 0,17739339 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,14849344 0,17730669 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,14849344 0,17722007 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,14849344 0,17713353 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,14849344 0,17704709 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,14849344 0,17696072 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,14849344 0,17687444 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,14849344 0,17678825 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,14849344 0,17670213 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,14849344 0,1766161 ! blastocyst development GO:0001824 50 26 0,000 0,14849344 0,17653016 ! telomere organization GO:0032200 46 26 0,000 0,14849344 0,1764443 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,14849344 0,17635852 ! alditol metabolic process GO:0019400 44 26 0,000 0,14849344 0,17627283 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,14849344 0,17618722 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,14849344 0,17610169 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,15374374 0,18223966 ! embryonic pattern specification GO:0009880 49 27 0,000 0,15374374 0,18215128 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,15374374 0,18206299 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,15374374 0,18197478 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,15374374 0,18188666 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,15374374 0,18179862 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,15374374 0,18171067 ! iron ion transport GO:0006826 65 27 0,000 0,15374374 0,1816228 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,15374374 0,18153502 ! superoxide metabolic process GO:0006801 41 27 0,000 0,15374374 0,18144732 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,15374374 0,1813597 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,15374374 0,18127218 ! response to toxin GO:0009636 49 27 0,000 0,15374374 0,18118473 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,15374374 0,18109737 ! leukocyte proliferation GO:0070661 59 27 0,000 0,15374374 0,18101009 GO:0032943|mononuclear cell proliferation, ! vesicle docking GO:0048278 55 28 0,000 0,1589618 0,18706343 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,1589618 0,18697337 ! fat cell differentiation GO:0045444 57 28 0,000 0,1589618 0,18688339 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,1589618 0,1867935 ! sperm motility GO:0030317 37 28 0,000 0,1589618 0,1867037 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,1589618 0,18661398 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,1589618 0,18652435 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,1589618 0,1864348 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,1589618 0,18634534 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,1589618 0,18625596 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,1589618 0,18616668 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,1589618 0,18607747 ! glutathione metabolic process GO:0006749 42 28 0,000 0,1589618 0,18598836 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,1589618 0,18589932 ! lipid oxidation GO:0034440 48 28 0,000 0,1589618 0,18581038 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,1589618 0,18572151 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,1589618 0,18563274 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,16414784 0,19159732 ! translational initiation GO:0006413 66 29 0,000 0,16414784 0,19150582 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,16414784 0,19141441 ! catechol metabolic process GO:0009712 55 29 0,000 0,16414784 0,19132308 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,16414784 0,19123185 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,16414784 0,1911407 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,16414784 0,19104963 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,16414784 0,19095866 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,16414784 0,19086777 ! synaptogenesis GO:0007416 46 29 0,000 0,16414784 0,19077697 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,16414784 0,19068625 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,16414784 0,19059562 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,16414784 0,19050507 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,16414784 0,19041462 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,16930205 0,19630038 ! phenol metabolic process GO:0018958 56 30 0,000 0,16930205 0,19620726 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,16930205 0,19611423 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,16930205 0,19602128 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,16930205 0,19592843 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,16930205 0,19583566 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,16930205 0,19574297 ! acute-phase response GO:0006953 50 30 0,000 0,16930205 0,19565038 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,16930205 0,19555787 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,16930205 0,19546546 ! myofibril assembly GO:0030239 50 30 0,000 0,16930205 0,19537312 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,16930205 0,19528088 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,16930205 0,19518872 ! cell fate determination GO:0001709 64 30 0,000 0,16930205 0,19509665 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,16930205 0,19500467 ! phospholipid transport GO:0015914 65 30 0,000 0,16930205 0,19491277 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,16930205 0,19482096 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,16930205 0,19472924 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,16930205 0,1946376 ! regulation of coagulation GO:0050818 52 30 0,000 0,16930205 0,19454605 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,17442462 0,20033819 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,17442462 0,20024405 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,17442462 0,20014999 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,17442462 0,20005603 ! cell junction assembly GO:0034329 85 31 0,000 0,17442462 0,19996215 ! regulation of innate immune response GO:0045088 57 31 0,000 0,17442462 0,19986836 ! ovulation cycle process GO:0022602 55 31 0,000 0,17442462 0,19977465 ! peptide transport GO:0015833 60 31 0,000 0,17442462 0,19968104 ! male gonad development GO:0008584 56 31 0,000 0,17442462 0,19958751 ! iron ion homeostasis GO:0055072 60 31 0,000 0,17442462 0,19949407 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,17442462 0,19940072 ! detection of light stimulus GO:0009583 44 31 0,000 0,17442462 0,19930745 ! natural killer cell activation GO:0030101 50 31 0,000 0,17442462 0,19921428 ! cofactor catabolic process GO:0051187 54 31 0,000 0,17442462 0,19912119 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,17442462 0,19902818 ! response to heat GO:0009408 54 31 0,000 0,17442462 0,19893526 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,17442462 0,19884243 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,17951574 0,20455082 ! collagen metabolic process GO:0032963 49 32 0,000 0,17951574 0,20445545 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,17951574 0,20436018 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,17951574 0,204265 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,17951574 0,2041699 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,17951574 0,20407489 ! muscle cell development GO:0055001 52 32 0,000 0,17951574 0,20397998 ! mesoderm formation GO:0001707 73 32 0,000 0,17951574 0,20388515 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,17951574 0,2037904 ! ovulation cycle GO:0042698 57 32 0,000 0,17951574 0,20369575 ! BMP signaling pathway GO:0030509 71 32 0,000 0,17951574 0,20360118 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,17951574 0,2035067 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,17951574 0,20341231 ! gene silencing GO:0016458 71 32 0,000 0,17951574 0,20331801 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,18457561 0,2089519 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,18457561 0,20885512 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,18457561 0,20875843 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,18457561 0,20866183 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,18457561 0,20856531 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,18457561 0,20846889 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,18457561 0,20837255 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,18457561 0,20827631 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,18457561 0,20818015 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,18457561 0,20808408 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,18457561 0,2079881 ! glial cell differentiation GO:0010001 67 34 0,000 0,18960441 0,21355628 ! post-embryonic development GO:0009791 76 34 0,000 0,18960441 0,21345787 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,18960441 0,21335955 ! cholesterol transport GO:0030301 62 34 0,000 0,18960441 0,21326132 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,18960441 0,21316318 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,18960441 0,21306512 ! formation of primary germ layer GO:0001704 76 34 0,000 0,18960441 0,21296716 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,18960441 0,21286929 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,18960441 0,21277151 ! adult locomotory behavior GO:0008344 62 34 0,000 0,18960441 0,21267382 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,19460235 0,21817968 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,19460235 0,2180796 ! membrane docking GO:0022406 69 35 0,000 0,19460235 0,21797961 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,19460235 0,21787971 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,19460235 0,21777991 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,19460235 0,21768019 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,19460235 0,21758056 ! ceramide metabolic process GO:0006672 72 35 0,000 0,19460235 0,21748103 ! sterol transport GO:0015918 63 35 0,000 0,19460235 0,21738159 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,19460235 0,21728224 ! placenta development GO:0001890 53 35 0,000 0,19460235 0,21718298 ! vesicle localization GO:0051648 70 35 0,000 0,19460235 0,21708381 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,1995696 0,22252329 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,1995696 0,22242177 ! positive regulation of cell development GO:0010720 85 36 0,000 0,1995696 0,22232035 ! protein targeting to membrane GO:0006612 75 36 0,000 0,1995696 0,22221902 ! regulation of proteolysis GO:0030162 77 36 0,000 0,1995696 0,22211778 ! aerobic respiration GO:0009060 56 36 0,000 0,1995696 0,22201663 ! cytokine production GO:0001816 68 36 0,000 0,1995696 0,22191558 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,1995696 0,22181462 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,1995696 0,22171375 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,20450635 0,22709501 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,20450635 0,22699183 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,20450635 0,22688874 ! actomyosin structure organization GO:0031032 68 37 0,000 0,20450635 0,22678575 ! cell junction organization GO:0034330 96 37 0,000 0,20450635 0,22668286 ! tissue remodeling GO:0048771 78 37 0,000 0,20450635 0,22658005 ! female gonad development GO:0008585 71 37 0,000 0,20450635 0,22647734 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,20450635 0,22637472 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,20941279 0,23170084 ! organic anion transport GO:0015711 82 38 0,000 0,20941279 0,23159595 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,20941279 0,23149116 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,20941279 0,23138646 ! spermatid development GO:0007286 69 38 0,000 0,20941279 0,23128185 ! pigment metabolic process GO:0042440 87 38 0,000 0,20941279 0,23117734 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,21428911 0,23645362 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,21428911 0,23634687 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,21428911 0,23624021 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,21428911 0,23613365 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,21428911 0,23602719 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,21428911 0,23592082 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,21428911 0,23581455 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,21913549 0,24103918 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,21913549 0,2409307 ! learning GO:0007612 82 40 0,000 0,21913549 0,24082232 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,21913549 0,24071403 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 0,000 0,21913549 0,24060585 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,21913549 0,24049776 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,22395211 0,24567356 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,22395211 0,24556329 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,22395211 0,24545313 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,22395211 0,24534306 ! gliogenesis GO:0042063 91 41 0,000 0,22395211 0,24523309 ! feeding behavior GO:0007631 69 41 0,000 0,22395211 0,24512322 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,22395211 0,24501344 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,22395211 0,24490377 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,22395211 0,24479419 ! RNA modification GO:0009451 64 41 0,000 0,22395211 0,24468471 ! ear morphogenesis GO:0042471 64 42 0,000 0,22873916 0,2498032 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,22873916 0,24969159 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,22873916 0,24958007 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,22873916 0,24946865 ! regulation of protein secretion GO:0050708 77 42 0,000 0,22873916 0,24935733 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,23349681 0,25443029 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,23349681 0,25431686 ! regulation of tube size GO:0035150 76 43 0,000 0,23349681 0,25420353 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,23349681 0,25409029 ! glucose transport GO:0015758 66 43 0,000 0,23349681 0,25397716 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,23349681 0,25386413 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,23349681 0,25375121 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,23349681 0,25363838 ! ion transmembrane transport GO:0034220 79 43 0,000 0,23349681 0,25352565 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,23349681 0,25341302 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,23822525 0,25842996 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,23822525 0,25831526 ! hexose transport GO:0008645 68 44 0,000 0,23822525 0,25820066 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,23822525 0,25808615 ! striated muscle contraction GO:0006941 85 44 0,000 0,23822525 0,25797175 ! phagocytosis GO:0006909 105 44 0,000 0,23822525 0,25785746 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,23822525 0,25774326 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,24292465 0,26271134 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,24292465 0,26259509 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,24292465 0,26247895 ! female gamete generation GO:0007292 71 45 0,000 0,24292465 0,26236291 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,24292465 0,26224698 ! polyol metabolic process GO:0019751 77 45 0,000 0,24292465 0,26213114 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,24759519 0,267053 ! glycolysis GO:0006096 71 46 0,000 0,24759519 0,26693515 ! leukocyte migration GO:0050900 75 46 0,000 0,24759519 0,2668174 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,24759519 0,26669975 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,24759519 0,26658221 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,24759519 0,26646478 ! pigmentation GO:0043473 103 46 0,000 0,24759519 0,26634744 ! cell growth GO:0016049 90 46 0,000 0,24759519 0,26623021 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,25223704 0,27110211 ! positive regulation of defense response GO:0031349 88 48 0,000 0,25685039 0,2759391 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,25685039 0,27581781 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,25685039 0,27569662 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,25685039 0,27557554 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,25685039 0,27545457 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,25685039 0,2753337 ! response to calcium ion GO:0051592 94 49 0,000 0,26143541 0,28012575 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,26143541 0,28000294 ! JNK cascade GO:0007254 106 49 0,000 0,26143541 0,27988024 ! protein homooligomerization GO:0051260 84 49 0,000 0,26143541 0,27975765 ! regulation of ion transport GO:0043269 86 50 0,000 0,26599227 0,28450924 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,26599227 0,28438473 ! endocrine system development GO:0035270 109 50 0,000 0,26599227 0,28426033 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,26599227 0,28413603 ! regulation of ossification GO:0030278 123 50 0,000 0,26599227 0,28401185 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,26599227 0,28388777 GO:0019724|B cell mediated immunity, ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,26599227 0,2837638 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,27052114 0,28846929 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,27052114 0,28834343 ! peptide metabolic process GO:0006518 80 51 0,000 0,27052114 0,28821768 ! response to temperature stimulus GO:0009266 84 51 0,000 0,27052114 0,28809204 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,27052114 0,28796651 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,27502219 0,29263032 ! Notch signaling pathway GO:0007219 111 52 0,000 0,27502219 0,29250292 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,27502219 0,29237564 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,27502219 0,29224846 ! excretion GO:0007588 87 52 0,000 0,27502219 0,2921214 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,27502219 0,29199444 ! amino acid activation GO:0043038 98 52 0,000 0,27502219 0,2918676 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,2794956 0,29648621 ! inner ear development GO:0048839 89 53 0,000 0,2794956 0,29635753 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,2794956 0,29622896 ! vesicle organization GO:0016050 127 53 0,000 0,2794956 0,2961005 ! cartilage development GO:0051216 99 53 0,000 0,2794956 0,29597215 ! regulation of translational initiation GO:0006446 87 54 0,000 0,28394153 0,30054989 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,28394153 0,30041973 ! neuromuscular process GO:0050905 107 54 0,000 0,28394153 0,30028967 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,28394153 0,30015974 ! membrane fusion GO:0006944 122 54 0,000 0,28394153 0,30002991 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,28394153 0,29990019 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,28394153 0,29977059 ! regulation of cell shape GO:0008360 142 54 0,000 0,28394153 0,2996411 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,28836015 0,30417264 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,28836015 0,30404136 ! cell recognition GO:0008037 98 55 0,000 0,28836015 0,3039102 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,28836015 0,30377914 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,28836015 0,3036482 ! glucose catabolic process GO:0006007 88 56 0,000 0,29275162 0,30813969 ! chloride transport GO:0006821 102 57 0,000 0,29711612 0,31259892 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,29711612 0,31246435 ! regulation of actin filament length GO:0030832 118 58 0,000 0,30145381 0,3168897 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,30145381 0,3167534 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,30145381 0,31661722 ! gastrulation GO:0007369 122 58 0,000 0,30145381 0,31648116 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,30145381 0,31634522 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,30145381 0,31620939 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,31004941 0,32508614 ! regulation of endocytosis GO:0030100 104 60 0,000 0,31004941 0,32494668 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,31004941 0,32480734 ! adult behavior GO:0030534 104 60 0,000 0,31004941 0,32466811 ! regulation of cellular component size GO:0032535 125 61 0,000 0,31430764 0,32898611 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,31430764 0,32884521 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,31430764 0,32870444 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,31430764 0,32856379 ! regulation of heart contraction GO:0008016 123 61 0,000 0,31430764 0,32842326 ! proton transport GO:0015992 117 61 0,000 0,31430764 0,32828285 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,31430764 0,32814255 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,31853972 0,33241885 ! tRNA processing GO:0008033 102 62 0,000 0,31853972 0,33227691 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,31853972 0,3321351 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,32274579 0,33637712 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,32274579 0,33623367 ! hydrogen transport GO:0006818 121 64 0,000 0,32692602 0,34044342 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,32692602 0,34029836 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,32692602 0,34015343 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,33108056 0,34432942 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,33108056 0,3441829 ! ear development GO:0043583 114 66 0,000 0,33520957 0,34832709 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,33520957 0,34817899 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,33520957 0,34803102 ! gonad development GO:0008406 115 66 0,000 0,33520957 0,34788317 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,33931322 0,35199244 ! secondary metabolic process GO:0019748 125 67 0,000 0,33931322 0,35184304 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,33931322 0,35169376 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,34339165 0,35577006 ! hexose catabolic process GO:0019320 113 68 0,000 0,34339165 0,35561924 ! detection of external stimulus GO:0009581 102 68 0,000 0,34339165 0,35546856 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,34339165 0,355318 ! adaptive immune response GO:0002250 126 68 0,000 0,34339165 0,35516757 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,34744501 0,35920786 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,34744501 0,35905591 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,34744501 0,35890409 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,34744501 0,3587524 ! single fertilization GO:0007338 83 69 0,000 0,34744501 0,35860083 ! germ cell development GO:0007281 133 70 0,000 0,35147347 0,36260544 ! activation of immune response GO:0002253 120 70 0,000 0,35147347 0,36245238 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,35147347 0,36229945 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,35547717 0,36627193 ! carbohydrate transport GO:0008643 114 72 0,000 0,35945627 0,37021571 ! actin filament organization GO:0007015 167 72 0,000 0,35945627 0,3700597 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,35945627 0,36990382 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,35945627 0,36974807 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,35945627 0,36959245 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,35945627 0,36943697 ! humoral immune response GO:0006959 115 73 0,000 0,36341091 0,37334435 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,36341091 0,37318742 ! regulation of immune effector process GO:0002697 156 73 0,000 0,36341091 0,37303061 ! acute inflammatory response GO:0002526 118 74 0,000 0,36734125 0,37690663 ! amino acid transport GO:0006865 148 74 0,000 0,36734125 0,37674839 ! transition metal ion transport GO:0000041 143 75 0,000 0,37124743 0,38059483 ! reproductive structure development GO:0048608 131 75 0,000 0,37124743 0,38043518 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,37124743 0,38027567 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,37512961 0,38409121 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,37512961 0,3839303 ! learning or memory GO:0007611 161 76 0,000 0,37512961 0,38376953 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,37512961 0,38360889 ! regulation of blood pressure GO:0008217 134 76 0,000 0,37512961 0,38344838 ! amine catabolic process GO:0009310 136 77 0,000 0,37898792 0,38723023 ! neurotransmitter transport GO:0006836 142 77 0,000 0,37898792 0,38706835 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,37898792 0,3869066 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,37898792 0,38674498 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,37898792 0,3865835 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,37898792 0,38642216 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,38282251 0,39016913 ! antigen processing and presentation GO:0019882 117 78 0,000 0,38282251 0,39000642 ! fertilization GO:0009566 99 78 0,000 0,38282251 0,38984385 ! blood coagulation GO:0007596 151 79 0,000 0,38663354 0,39356073 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,38663354 0,39339681 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,38663354 0,39323303 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,38663354 0,39306939 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,38663354 0,39290588 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,39042114 0,39658996 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,39042114 0,39642512 ! muscle cell differentiation GO:0042692 178 81 0,000 0,39418546 0,40008105 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,39792664 0,40371046 ! exocytosis GO:0006887 153 83 0,000 0,40164482 0,40731353 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,40164482 0,40714452 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,40164482 0,40697565 ! inorganic anion transport GO:0015698 156 83 0,000 0,40164482 0,40680692 ! response to metal ion GO:0010038 158 84 0,000 0,40534014 0,41037959 ! digestion GO:0007586 130 84 0,000 0,40534014 0,41020959 ! hemostasis GO:0007599 165 85 0,000 0,40901274 0,41375492 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,40901274 0,41358366 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,40901274 0,41341255 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,41629035 0,42059443 ! alcohol catabolic process GO:0046164 142 87 0,000 0,41629035 0,42042055 ! nucleosome assembly GO:0006334 126 87 0,000 0,41629035 0,42024683 ! cellular respiration GO:0045333 143 88 0,000 0,41989563 0,42371129 ! amine biosynthetic process GO:0009309 146 88 0,000 0,41989563 0,42353634 ! sensory perception of smell GO:0007608 117 88 0,000 0,41989563 0,42336154 ! chromatin assembly GO:0031497 128 88 0,000 0,41989563 0,42318689 ! cellular defense response GO:0006968 123 89 0,000 0,42347874 0,42662209 ! regulation of neurological system process GO:0031644 175 89 0,000 0,42347874 0,42644624 ! response to inorganic substance GO:0010035 173 90 0,000 0,42703982 0,42985508 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,42703982 0,42967804 ! defense response to bacterium GO:0042742 112 91 0,000 0,43057901 0,43306073 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,43409643 0,43641876 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,43759223 0,43975229 ! amine transport GO:0015837 181 93 0,000 0,43759223 0,43957147 ! vitamin metabolic process GO:0006766 153 93 0,000 0,43759223 0,4393908 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,44106652 0,44269742 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,44106652 0,44251561 ! regulation of defense response GO:0031347 171 95 0,000 0,44451945 0,44579681 ! nucleosome organization GO:0034728 143 95 0,000 0,44451945 0,44561388 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,44451945 0,4454311 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,44451945 0,44524847 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,44451945 0,445066 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,44451945 0,44488367 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,45136175 0,45154658 ! positive regulation of immune response GO:0050778 175 100 0,000 0,46146819 0,46146819