pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6918-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 3,000 1,792E-07 3,302E-04 ! regulation of cell migration GO:0030334 71 71 6,000 2,609E-07 2,404E-04 ! regulation of locomotion GO:0040012 79 79 6,000 5,475E-07 3,363E-04 ! regulation of cell motion GO:0051270 79 79 6,000 5,475E-07 2,523E-04 ! heart development GO:0007507 90 87 6,000 1,063E-06 3,917E-04 ! positive regulation of cell migration GO:0030335 36 36 4,000 2,756E-06 8,465E-04 ! positive regulation of cell motion GO:0051272 39 39 4,000 4,149E-06 1,092E-03 ! mammary gland development GO:0030879 23 21 3,000 8,047E-06 1,854E-03 ! gland development GO:0048732 51 49 4,000 1,311E-05 2,684E-03 ! anterior/posterior pattern formation GO:0009952 51 50 4,000 1,449E-05 2,671E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 1,669E-05 2,797E-03 ! negative regulation of cell cycle GO:0045786 92 91 5,000 2,137E-05 3,282E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 2,295E-05 3,253E-03 ! blood vessel development GO:0001568 95 94 5,000 2,573E-05 3,388E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,665E-05 3,274E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 2,000 2,839E-05 3,27E-03 ! vasculature development GO:0001944 97 96 5,000 2,902E-05 3,146E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 3,886E-05 3,979E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 4,038E-05 3,917E-03 ! lipid transport GO:0006869 62 62 4,000 4,182E-05 3,854E-03 ! vasculogenesis GO:0001570 13 13 2,000 6,676E-05 5,859E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 6,676E-05 5,593E-03 ! negative regulation of intracellular transport GO:0032387 13 13 2,000 6,676E-05 5,349E-03 ! protein tetramerization GO:0051262 13 13 2,000 6,676E-05 5,127E-03 ! regionalization GO:0003002 70 69 4,000 7,027E-05 5,18E-03 ! lung development GO:0030324 38 37 3,000 8,242E-05 5,843E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 8,459E-05 5,774E-03 ! respiratory tube development GO:0030323 40 39 3,000 1,017E-04 6,694E-03 ! respiratory system development GO:0060541 40 39 3,000 1,017E-04 6,463E-03 ! protein import into nucleus, translocation GO:0000060 15 15 2,000 1,053E-04 6,467E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 1,053E-04 6,258E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 1,29E-04 7,428E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 1,559E-04 8,708E-03 ! tissue remodeling GO:0048771 17 17 2,000 1,559E-04 8,452E-03 ! blood vessel morphogenesis GO:0048514 84 83 4,000 1,699E-04 8,947E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 1,863E-04 9,536E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 2,009E-04 0,01000813 ! positive regulation of transferase activity GO:0051347 91 88 4,000 2,239E-04 0,01085855 GO:0033674|positive regulation of kinase activity, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 2,501E-04 0,0118172 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 2,995E-04 0,01380175 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 2,995E-04 0,01346512 ! negative regulation of protein transport GO:0051224 21 21 2,000 2,995E-04 0,01314452 ! pattern specification process GO:0007389 96 94 4,000 3,049E-04 0,01306905 ! cell fate commitment GO:0045165 52 52 3,000 3,151E-04 0,0131983 ! regulation of protein transport GO:0051223 53 53 3,000 3,392E-04 0,01389376 GO:0070201|regulation of establishment of protein localization, ! neuron fate specification GO:0048665 5 5 1,000 3,949E-04 0,01582203 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 3,949E-04 0,01548539 ! forebrain regionalization GO:0021871 5 5 1,000 3,949E-04 0,01516278 ! mRNA stabilization GO:0048255 5 5 1,000 3,949E-04 0,01485334 GO:0043489|RNA stabilization, ! paraxial mesoderm development GO:0048339 5 5 1,000 3,949E-04 0,01455627 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,949E-04 0,01427085 ! protein heterooligomerization GO:0051291 5 5 1,000 3,949E-04 0,01399641 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 3,949E-04 0,01373233 ! decidualization GO:0046697 5 5 1,000 3,949E-04 0,01347803 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 3,949E-04 0,01323297 GO:0021517|ventral spinal cord development, ! T cell lineage commitment GO:0002360 5 5 1,000 3,949E-04 0,01299667 ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,949E-04 0,01276866 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 3,949E-04 0,01254851 ! nucleosome positioning GO:0016584 5 5 1,000 3,949E-04 0,01233582 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 3,949E-04 0,01213022 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 3,949E-04 0,01193137 GO:0007439|ectodermal gut development, ! blastocyst formation GO:0001825 5 5 1,000 3,949E-04 0,01173893 ! embryonic gut development GO:0048566 5 5 1,000 3,949E-04 0,01155259 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 3,949E-04 0,01137208 ! B cell receptor signaling pathway GO:0050853 5 5 1,000 3,949E-04 0,01119713 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 3,953E-04 0,01103921 ! regulation of binding GO:0051098 60 57 3,000 4,492E-04 0,01235627 ! regulation of protein localization GO:0032880 58 57 3,000 4,492E-04 0,01217456 ! T cell differentiation GO:0030217 24 24 2,000 4,498E-04 0,01201395 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 5,088E-04 0,01339725 ! negative regulation of cell migration GO:0030336 26 26 2,000 5,727E-04 0,01486492 ! response to insulin stimulus GO:0032868 28 26 2,000 5,727E-04 0,01465846 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 5,9E-04 0,01489426 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 5,9E-04 0,01469299 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 5,9E-04 0,01449708 GO:0050927|positive regulation of positive chemotaxis, ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 5,9E-04 0,01430633 ! ER overload response GO:0006983 6 6 1,000 5,9E-04 0,01412053 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 5,9E-04 0,0139395 GO:0070667|negative regulation of mast cell proliferation, ! lipid digestion GO:0044241 6 6 1,000 5,9E-04 0,01376305 ! regulation of vascular permeability GO:0043114 6 6 1,000 5,9E-04 0,01359101 ! regulation of bone resorption GO:0045124 6 6 1,000 5,9E-04 0,01342322 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 5,9E-04 0,01325953 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 5,9E-04 0,01309977 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 5,9E-04 0,01294382 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 5,9E-04 0,01279154 ! intestinal absorption GO:0050892 6 6 1,000 5,9E-04 0,0126428 ! thymus development GO:0048538 6 6 1,000 5,9E-04 0,01249748 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 5,9E-04 0,01235547 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! maternal placenta development GO:0001893 6 6 1,000 5,9E-04 0,01221664 ! regulation of embryonic development GO:0045995 6 6 1,000 5,9E-04 0,0120809 ! localization within membrane GO:0051668 6 6 1,000 5,9E-04 0,01194814 ! angiogenesis GO:0001525 65 64 3,000 6,994E-04 0,01401138 ! DNA packaging GO:0006323 66 66 3,000 7,86E-04 0,01557723 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 7,86E-04 0,01541151 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 7,941E-04 0,01540566 ! response to UV GO:0009411 29 29 2,000 7,941E-04 0,01524518 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 8,226E-04 0,01562894 ! cell differentiation in spinal cord GO:0021515 7 7 1,000 8,226E-04 0,01546946 ! cardiac muscle tissue development GO:0048738 7 7 1,000 8,226E-04 0,0153132 ! response to X-ray GO:0010165 7 7 1,000 8,226E-04 0,01516007 ! regulation of intracellular pH GO:0051453 7 7 1,000 8,226E-04 0,01500997 ! response to gamma radiation GO:0010332 8 7 1,000 8,226E-04 0,01486281 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 8,226E-04 0,01471851 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 8,226E-04 0,01457699 ! T cell receptor signaling pathway GO:0050852 7 7 1,000 8,226E-04 0,01443816 ! negative regulation of T cell activation GO:0050868 7 7 1,000 8,226E-04 0,01430195 ! digestive system development GO:0055123 7 7 1,000 8,226E-04 0,01416829 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of defense response to virus GO:0050688 7 7 1,000 8,226E-04 0,0140371 ! regulation of mRNA processing GO:0050684 7 7 1,000 8,226E-04 0,01390832 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 8,226E-04 0,01378188 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 8,226E-04 0,01365772 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cranial nerve development GO:0021545 7 7 1,000 8,226E-04 0,01353578 ! striated muscle tissue development GO:0014706 69 67 3,000 8,321E-04 0,01357105 ! chromatin assembly or disassembly GO:0006333 68 68 3,000 8,8E-04 0,01422659 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 9,298E-04 0,01490145 ! regulation of DNA replication GO:0006275 32 31 2,000 9,682E-04 0,01538275 ! negative regulation of cell motion GO:0051271 31 31 2,000 9,682E-04 0,01525127 ! muscle tissue development GO:0060537 72 70 3,000 9,816E-04 0,01533146 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,092E-03 0,01691706 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,092E-03 0,01677609 ! sex determination GO:0007530 8 8 1,000 1,092E-03 0,01663744 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,092E-03 0,01650107 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,092E-03 0,01636691 ! regulation of RNA stability GO:0043487 8 8 1,000 1,092E-03 0,01623492 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,092E-03 0,01610504 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,092E-03 0,01597722 ! regulation of multi-organism process GO:0043900 8 8 1,000 1,092E-03 0,01585142 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 1,272E-03 0,01831206 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,385E-03 0,01978521 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,399E-03 0,01982922 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,399E-03 0,01967786 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 1,000 1,399E-03 0,01952878 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,399E-03 0,01938195 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,399E-03 0,01923731 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,399E-03 0,01909481 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,399E-03 0,0189544 ! regulation of cellular pH GO:0030641 9 9 1,000 1,399E-03 0,01881605 ! histone acetylation GO:0016573 9 9 1,000 1,399E-03 0,0186797 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,399E-03 0,01854532 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,399E-03 0,01841285 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,399E-03 0,01828226 ! actin filament-based movement GO:0030048 9 9 1,000 1,399E-03 0,01815351 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 1,629E-03 0,02100088 ! MAPKKK cascade GO:0000165 82 81 3,000 1,693E-03 0,02166295 ! tube development GO:0035295 83 81 3,000 1,693E-03 0,02151355 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,741E-03 0,0219806 ! inositol metabolic process GO:0006020 10 10 1,000 1,741E-03 0,02183108 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,741E-03 0,02168357 ! neuromuscular junction development GO:0007528 10 10 1,000 1,741E-03 0,02153804 ! gland morphogenesis GO:0022612 10 10 1,000 1,741E-03 0,02139445 ! nerve development GO:0021675 10 10 1,000 1,741E-03 0,02125277 ! gut development GO:0048565 10 10 1,000 1,741E-03 0,02111295 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 1,741E-03 0,02097496 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,741E-03 0,02083875 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,741E-03 0,02070431 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 1,000 1,741E-03 0,02057159 ! negative regulation of kinase activity GO:0033673 38 38 2,000 1,761E-03 0,02067548 ! chromosome segregation GO:0007059 38 38 2,000 1,761E-03 0,02054463 ! lymphocyte differentiation GO:0030098 39 39 2,000 1,9E-03 0,02201847 ! protein oligomerization GO:0051259 39 39 2,000 1,9E-03 0,02188085 ! regulation of cellular localization GO:0060341 86 85 3,000 2,022E-03 0,02314721 ! negative regulation of transferase activity GO:0051348 40 40 2,000 2,044E-03 0,02325919 ! endothelial cell migration GO:0043542 11 11 1,000 2,12E-03 0,02396565 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,12E-03 0,02381952 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 2,12E-03 0,02367516 GO:0032388|positive regulation of intracellular transport, ! spinal cord development GO:0021510 11 11 1,000 2,12E-03 0,02353254 ! activation of MAPKK activity GO:0000186 12 11 1,000 2,12E-03 0,02339162 ! cellular response to starvation GO:0009267 11 11 1,000 2,12E-03 0,02325239 ! digestive system process GO:0022600 11 11 1,000 2,12E-03 0,0231148 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,12E-03 0,02297883 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,12E-03 0,02284445 ! interaction with host GO:0051701 11 11 1,000 2,12E-03 0,02271163 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,12E-03 0,02258035 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,12E-03 0,02245058 GO:0006109|regulation of carbohydrate metabolic process, ! proximal/distal pattern formation GO:0009954 11 11 1,000 2,12E-03 0,02232229 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,12E-03 0,02219546 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,196E-03 0,02286674 ! protein ubiquitination GO:0016567 43 42 2,000 2,355E-03 0,02437867 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,533E-03 0,02608194 ! mitotic chromosome condensation GO:0007076 12 12 1,000 2,533E-03 0,02593704 ! osteoblast differentiation GO:0001649 12 12 1,000 2,533E-03 0,02579374 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 2,533E-03 0,02565202 ! somitogenesis GO:0001756 13 12 1,000 2,533E-03 0,02551184 ! regulation of response to biotic stimulus GO:0002831 12 12 1,000 2,533E-03 0,02537319 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 2,533E-03 0,02523604 ! negative regulation of translation GO:0017148 12 12 1,000 2,533E-03 0,02510036 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 2,533E-03 0,02496613 ! protein import into nucleus GO:0006606 44 44 2,000 2,692E-03 0,02639286 ! tissue morphogenesis GO:0048729 94 93 3,000 2,81E-03 0,02739924 ! regulation of DNA binding GO:0051101 47 45 2,000 2,872E-03 0,02785628 ! nuclear import GO:0051170 45 45 2,000 2,872E-03 0,02771043 ! positive regulation of DNA replication GO:0045740 14 13 1,000 2,982E-03 0,02862055 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 2,982E-03 0,02847226 ! mitochondrial membrane organization GO:0007006 13 13 1,000 2,982E-03 0,02832549 ! negative regulation of DNA replication GO:0008156 13 13 1,000 2,982E-03 0,02818023 ! ureteric bud development GO:0001657 13 13 1,000 2,982E-03 0,02803646 ! cell aging GO:0007569 13 13 1,000 2,982E-03 0,02789414 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 2,982E-03 0,02775326 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,982E-03 0,0276138 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,982E-03 0,02747573 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 2,982E-03 0,02733903 ! regulation of viral reproduction GO:0050792 13 13 1,000 2,982E-03 0,02720369 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,982E-03 0,02706968 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,982E-03 0,02693699 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 2,982E-03 0,02680559 GO:0001952|regulation of cell-matrix adhesion, ! camera-type eye morphogenesis GO:0048593 13 13 1,000 2,982E-03 0,02667546 ! blastocyst development GO:0001824 13 13 1,000 2,982E-03 0,0265466 ! tissue homeostasis GO:0001894 13 13 1,000 2,982E-03 0,02641897 GO:0048871|multicellular organismal homeostasis, ! cellular response to hormone stimulus GO:0032870 48 46 2,000 3,059E-03 0,02697052 ! regulation of cell growth GO:0001558 97 96 3,000 3,153E-03 0,02766955 ! regulation of catabolic process GO:0009894 48 47 2,000 3,253E-03 0,0284098 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 3,397E-03 0,02952933 ! regulation of cell cycle process GO:0010564 50 48 2,000 3,454E-03 0,02988616 ! protein localization in nucleus GO:0034504 48 48 2,000 3,454E-03 0,0297465 ! neuron fate commitment GO:0048663 14 14 1,000 3,464E-03 0,02969777 ! protein amino acid acylation GO:0043543 14 14 1,000 3,464E-03 0,02956028 ! macromolecular complex disassembly GO:0032984 15 14 1,000 3,464E-03 0,02942406 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 1,000 3,464E-03 0,02928908 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of behavior GO:0050795 14 14 1,000 3,464E-03 0,02915534 ! base-excision repair GO:0006284 14 14 1,000 3,464E-03 0,02902282 ! formation of primary germ layer GO:0001704 14 14 1,000 3,464E-03 0,02889149 GO:0001707|mesoderm formation, ! response to hormone stimulus GO:0009725 102 100 3,000 3,653E-03 0,03032905 ! muscle organ development GO:0007517 102 100 3,000 3,653E-03 0,03019305 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 3,653E-03 0,03005826 ! leukocyte differentiation GO:0002521 50 49 2,000 3,663E-03 0,03000379 ! ossification GO:0001503 50 49 2,000 3,663E-03 0,02987103 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 2,000 3,663E-03 0,02973944 ! skeletal muscle tissue development GO:0007519 50 49 2,000 3,663E-03 0,029609 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 2,000 3,88E-03 0,0312224 ! negative regulation of transport GO:0051051 51 50 2,000 3,88E-03 0,03108665 ! chromatin assembly GO:0031497 50 50 2,000 3,88E-03 0,03095208 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 2,000 3,88E-03 0,03081867 ! protein amino acid O-linked glycosylation GO:0006493 15 15 1,000 3,981E-03 0,03149135 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 3,981E-03 0,03135677 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,981E-03 0,03122334 ! mesoderm morphogenesis GO:0048332 15 15 1,000 3,981E-03 0,03109104 ! chromosome condensation GO:0030261 15 15 1,000 3,981E-03 0,03095985 ! response to starvation GO:0042594 15 15 1,000 3,981E-03 0,03082977 ! response to ionizing radiation GO:0010212 16 15 1,000 3,981E-03 0,03070077 ! negative regulation of cell activation GO:0050866 15 15 1,000 3,981E-03 0,03057285 ! protein modification by small protein conjugation GO:0032446 52 51 2,000 4,104E-03 0,03138233 ! protein-DNA complex assembly GO:0065004 51 51 2,000 4,104E-03 0,03125265 ! response to light stimulus GO:0009416 53 52 2,000 4,336E-03 0,03288328 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 4,532E-03 0,03422844 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 4,532E-03 0,03408873 ! segmentation GO:0035282 17 16 1,000 4,532E-03 0,03395016 ! cell fate specification GO:0001708 16 16 1,000 4,532E-03 0,03381271 ! cellular response to nutrient levels GO:0031669 16 16 1,000 4,532E-03 0,03367637 ! polyol metabolic process GO:0019751 16 16 1,000 4,532E-03 0,03354112 ! response to hypoxia GO:0001666 53 53 2,000 4,575E-03 0,03373025 ! response to oxygen levels GO:0070482 55 54 2,000 4,823E-03 0,03541458 ! nucleosome organization GO:0034728 55 55 2,000 5,079E-03 0,03714392 ! in utero embryonic development GO:0001701 55 55 2,000 5,079E-03 0,0369971 ! regulation of cell adhesion GO:0030155 56 55 2,000 5,079E-03 0,03685144 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 5,079E-03 0,03670693 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 5,115E-03 0,03682419 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,115E-03 0,0366809 ! myelination GO:0042552 17 17 1,000 5,115E-03 0,03653873 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 5,115E-03 0,03639765 ! negative regulation of cell development GO:0010721 18 17 1,000 5,115E-03 0,03625766 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 1,000 5,115E-03 0,03611874 GO:0002764|immune response-regulating signal transduction, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 5,115E-03 0,03598088 ! embryonic organ development GO:0048568 17 17 1,000 5,115E-03 0,03584407 ! extracellular structure organization GO:0043062 56 56 2,000 5,343E-03 0,03729666 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 5,731E-03 0,03985832 ! cholesterol homeostasis GO:0042632 18 18 1,000 5,731E-03 0,03970848 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 5,731E-03 0,03955976 ! negative regulation of DNA binding GO:0043392 19 18 1,000 5,731E-03 0,03941214 ! telencephalon development GO:0021537 19 18 1,000 5,731E-03 0,03926563 ! B cell differentiation GO:0030183 18 18 1,000 5,731E-03 0,0391202 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 5,731E-03 0,03897585 ! ensheathment of neurons GO:0007272 18 18 1,000 5,731E-03 0,03883255 GO:0008366|axon ensheathment, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 5,731E-03 0,03869031 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 6,183E-03 0,0415869 ! protein localization in organelle GO:0033365 59 59 2,000 6,183E-03 0,04143568 ! DNA damage checkpoint GO:0000077 19 19 1,000 6,379E-03 0,0425991 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 6,379E-03 0,04244531 ! regulation of pH GO:0006885 19 19 1,000 6,379E-03 0,04229263 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 6,379E-03 0,04214105 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 6,379E-03 0,04199054 ! metanephros development GO:0001656 19 19 1,000 6,379E-03 0,04184111 ! peripheral nervous system development GO:0007422 19 19 1,000 6,379E-03 0,04169274 ! regulation of protein stability GO:0031647 19 19 1,000 6,379E-03 0,04154541 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 6,379E-03 0,04139913 ! eye morphogenesis GO:0048592 19 19 1,000 6,379E-03 0,04125387 ! regulation of cell shape GO:0008360 21 19 1,000 6,379E-03 0,04110962 ! placenta development GO:0001890 19 19 1,000 6,379E-03 0,04096638 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 7,06E-03 0,04517677 ! negative regulation of binding GO:0051100 21 20 1,000 7,06E-03 0,04502045 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 7,06E-03 0,04486521 ! neural tube development GO:0021915 21 20 1,000 7,06E-03 0,04471103 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 7,06E-03 0,04455791 ! chromatin remodeling GO:0006338 20 20 1,000 7,06E-03 0,04440584 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 7,06E-03 0,0442548 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 7,098E-03 0,04434346 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 2,000 7,098E-03 0,04419365 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 7,42E-03 0,0460427 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 7,771E-03 0,04806164 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 7,771E-03 0,04790089 ! cholesterol transport GO:0030301 21 21 1,000 7,771E-03 0,04774122 GO:0015918|sterol transport, ! DNA integrity checkpoint GO:0031570 21 21 1,000 7,771E-03 0,04758262 ! regulation of action potential in neuron GO:0019228 21 21 1,000 7,771E-03 0,04742506 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 7,771E-03 0,04726854 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 8,514E-03 0,05161502 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 8,514E-03 0,05144579 ! sister chromatid segregation GO:0000819 22 22 1,000 8,514E-03 0,05127766 ! odontogenesis GO:0042476 22 22 1,000 8,514E-03 0,05111064 ! embryonic skeletal system development GO:0048706 22 22 1,000 8,514E-03 0,05094469 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 8,794E-03 0,05244911 ! response to radiation GO:0009314 70 68 2,000 9,159E-03 0,05445138 ! epithelial cell differentiation GO:0030855 23 23 1,000 9,287E-03 0,05503522 ! endocrine system development GO:0035270 23 23 1,000 9,287E-03 0,05485883 ! positive regulation of growth GO:0045927 23 23 1,000 9,287E-03 0,05468356 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 9,287E-03 0,05450941 ! lipid homeostasis GO:0055088 23 23 1,000 9,287E-03 0,05433636 ! calcium-mediated signaling GO:0019722 23 23 1,000 9,287E-03 0,05416441 ! cell projection assembly GO:0030031 25 23 1,000 9,287E-03 0,05399354 ! mitochondrial transport GO:0006839 24 24 1,000 0,01009039 0,05847984 ! regulation of action potential GO:0001508 24 24 1,000 0,01009039 0,05829652 ! glucose homeostasis GO:0042593 24 24 1,000 0,01009039 0,05811434 GO:0033500|carbohydrate homeostasis, ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01009039 0,0579333 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01009039 0,05775338 ! negative regulation of signal transduction GO:0009968 71 71 2,000 0,01030768 0,05881438 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,01070839 0,06091223 ! cellular component disassembly GO:0022411 26 25 1,000 0,01092357 0,06194503 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01092357 0,06175502 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01092357 0,06156616 ! gastrulation GO:0007369 25 25 1,000 0,01092357 0,06137846 ! heart morphogenesis GO:0003007 25 25 1,000 0,01092357 0,0611919 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01092357 0,06100647 ! positive regulation of binding GO:0051099 27 26 1,000 0,01178614 0,06562496 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,01178614 0,0654273 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01178614 0,06523082 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01178614 0,06503552 ! double-strand break repair GO:0006302 27 26 1,000 0,01178614 0,06484138 ! synapse organization GO:0050808 26 26 1,000 0,01178614 0,0646484 ! negative regulation of cell communication GO:0010648 76 76 2,000 0,01240127 0,06782061 ! learning or memory GO:0007611 28 27 1,000 0,01267773 0,06912736 ! activation of caspase activity GO:0006919 27 27 1,000 0,01267773 0,06892344 ! regulation of immune response GO:0050776 78 78 2,000 0,0133022 0,07210572 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,01359792 0,07349259 GO:0007254|JNK cascade, ! histone modification GO:0016570 28 28 1,000 0,01359792 0,0732777 ! developmental growth GO:0048589 28 28 1,000 0,01359792 0,07306406 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01359792 0,07285167 ! nuclear transport GO:0051169 79 79 2,000 0,01376638 0,07354041 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 2,000 0,01423975 0,07584933 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01454635 0,07725917 ! viral reproductive process GO:0022415 29 29 1,000 0,01454635 0,07703716 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,01454635 0,07681642 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01454635 0,07659695 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01454635 0,07637872 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,01454635 0,07616174 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01454635 0,07594598 ! lymphocyte activation GO:0046649 82 81 2,000 0,01472234 0,07664765 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01552264 0,08058653 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01552264 0,08036017 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01552264 0,08013507 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,01552264 0,07991123 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01552264 0,07968863 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01652639 0,08460594 ! B cell activation GO:0042113 31 31 1,000 0,01652639 0,08437157 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,01652639 0,0841385 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01652639 0,08390672 ! aging GO:0007568 32 31 1,000 0,01652639 0,0836762 ! digestion GO:0007586 31 31 1,000 0,01652639 0,08344695 ! camera-type eye development GO:0043010 31 31 1,000 0,01652639 0,08321896 ! extracellular matrix organization GO:0030198 31 31 1,000 0,01652639 0,0829922 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,01674521 0,08386256 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,01727416 0,08627718 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,01755724 0,08745405 ! muscle fiber development GO:0048747 32 32 1,000 0,01755724 0,08721832 ! lipid modification GO:0030258 32 32 1,000 0,01755724 0,08698387 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01755724 0,08675066 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01755724 0,08651871 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,01755724 0,08628799 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01755724 0,0860585 ! kidney development GO:0001822 32 32 1,000 0,01755724 0,08583023 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01755724 0,08560317 ! negative regulation of cell size GO:0045792 33 33 1,000 0,01861482 0,09052009 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,01861482 0,09028188 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01861482 0,09004492 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01969876 0,09503878 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01969876 0,09479064 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01969876 0,09454379 ! viral reproduction GO:0016032 34 34 1,000 0,01969876 0,09429822 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,02064415 0,0985678 ! mesoderm development GO:0007498 35 35 1,000 0,02080869 0,0990967 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,02080869 0,09884129 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02080869 0,0985872 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,02080869 0,09833441 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02080869 0,09808292 ! regulation of immune effector process GO:0002697 35 35 1,000 0,02080869 0,09783271 ! epidermis development GO:0008544 94 94 2,000 0,0218425 0,10243189 ! regulation of mitosis GO:0007088 37 36 1,000 0,02194426 0,1026479 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,02194426 0,10238803 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02194426 0,10212948 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,02194426 0,10187222 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02194426 0,10161626 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02194426 0,10136159 ! activation of immune response GO:0002253 36 36 1,000 0,02194426 0,10110818 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02310511 0,1061913 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02310511 0,10592714 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,02310511 0,10566429 ! eye development GO:0001654 37 37 1,000 0,02310511 0,10540275 ! negative regulation of growth GO:0045926 37 37 1,000 0,02310511 0,10514249 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,02310511 0,10488352 ! adaptive immune response GO:0002250 37 37 1,000 0,02310511 0,10462582 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! urogenital system development GO:0001655 38 38 1,000 0,02429087 0,10972569 ! axon guidance GO:0007411 39 38 1,000 0,02429087 0,10945741 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,02429087 0,10919044 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,02429087 0,10892477 ! ectoderm development GO:0007398 99 99 2,000 0,02500292 0,11184557 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02550121 0,11379839 ! activation of MAPK activity GO:0000187 39 39 1,000 0,02550121 0,11352352 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,02550121 0,11324997 ! limb development GO:0060173 39 39 1,000 0,02550121 0,11297773 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! hemopoiesis GO:0030097 104 100 2,000 0,02566321 0,11342279 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02673578 0,11788048 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,02673578 0,11759914 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,02799422 0,12284132 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 0,02799422 0,12254953 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,02927621 0,12785794 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02927621 0,12755567 ! forebrain development GO:0030900 43 42 1,000 0,02927621 0,12725484 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02927621 0,12695541 ! mitochondrion organization GO:0007005 44 43 1,000 0,03058139 0,13230401 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03058139 0,13199417 ! rRNA transcription GO:0009303 5 5 0,000 0,03157941 0,1359833 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03157941 0,13566633 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03157941 0,13535082 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03157941 0,13503678 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03157941 0,1347242 ! reproductive cellular process GO:0048610 5 5 0,000 0,03157941 0,13441306 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03157941 0,13410335 ! prostate gland development GO:0030850 5 5 0,000 0,03157941 0,13379507 ! metencephalon development GO:0022037 5 5 0,000 0,03157941 0,1334882 ! water transport GO:0006833 5 5 0,000 0,03157941 0,13318273 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03157941 0,13287866 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03157941 0,13257598 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03157941 0,13227467 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03157941 0,13197473 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03157941 0,13167614 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03157941 0,1313789 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03157941 0,131083 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03157941 0,13078844 ! filopodium assembly GO:0046847 7 5 0,000 0,03157941 0,13049519 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03157941 0,13020325 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03157941 0,12991262 ! GTP metabolic process GO:0046039 5 5 0,000 0,03157941 0,12962328 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03157941 0,12933523 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03157941 0,12904846 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03157941 0,12876295 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03157941 0,12847871 ! social behavior GO:0035176 5 5 0,000 0,03157941 0,12819571 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03157941 0,12791396 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03157941 0,12763345 ! memory GO:0007613 5 5 0,000 0,03157941 0,12735417 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03157941 0,1270761 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03157941 0,12679925 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03157941 0,1265236 ! response to lipid GO:0033993 5 5 0,000 0,03157941 0,12624914 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03157941 0,12597587 ! hippocampus development GO:0021766 6 5 0,000 0,03157941 0,12570379 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03157941 0,12543287 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03157941 0,12516313 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03157941 0,12489454 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03157941 0,1246271 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03157941 0,1243608 ! heart looping GO:0001947 5 5 0,000 0,03157941 0,12409564 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03157941 0,1238316 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03157941 0,12356869 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03157941 0,12330689 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03157941 0,1230462 ! pH reduction GO:0045851 5 5 0,000 0,03157941 0,12278661 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03157941 0,12252811 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03157941 0,1222707 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03157941 0,12201437 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03157941 0,12175911 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03157941 0,12150491 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03157941 0,12125178 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03157941 0,1209997 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03157941 0,12074866 ! adrenal gland development GO:0030325 5 5 0,000 0,03157941 0,12049866 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03157941 0,1202497 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03157941 0,12000176 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03157941 0,11975484 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03157941 0,11950894 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03157941 0,11926404 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03157941 0,11902015 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03157941 0,11877725 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03157941 0,11853534 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03157941 0,11829442 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03157941 0,11805447 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03157941 0,11781549 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03157941 0,11757748 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03157941 0,11734043 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03157941 0,11710433 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03157941 0,11686918 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03157941 0,11663498 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03157941 0,11640171 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03157941 0,11616937 ! response to ATP GO:0033198 5 5 0,000 0,03157941 0,11593796 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03157941 0,11570746 ! regulation of appetite GO:0032098 5 5 0,000 0,03157941 0,11547788 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03157941 0,11524922 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03157941 0,11502145 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03157941 0,11479458 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03157941 0,11456861 ! receptor clustering GO:0043113 5 5 0,000 0,03157941 0,11434352 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03157941 0,11411932 ! fear response GO:0042596 5 5 0,000 0,03157941 0,113896 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03157941 0,11367354 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03157941 0,11345196 ! retinol metabolic process GO:0042572 5 5 0,000 0,03157941 0,11323123 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03157941 0,11301137 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03157941 0,11279235 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03157941 0,11257419 ! parturition GO:0007567 5 5 0,000 0,03157941 0,11235686 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03157941 0,11214037 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03157941 0,11192472 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03157941 0,11170989 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03157941 0,11149589 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03157941 0,1112827 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03157941 0,11107033 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03157941 0,11085877 ! response to UV-B GO:0010224 5 5 0,000 0,03157941 0,11064801 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03157941 0,11043805 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03157941 0,11022889 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03157941 0,11002052 ! interaction with symbiont GO:0051702 5 5 0,000 0,03157941 0,10981293 ! cellular extravasation GO:0045123 5 5 0,000 0,03157941 0,10960613 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03157941 0,1094001 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03157941 0,10919485 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03157941 0,10899036 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03157941 0,10878664 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03157941 0,10858368 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03157941 0,10838148 ! response to amine stimulus GO:0014075 5 5 0,000 0,03157941 0,10818003 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03157941 0,10797932 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03157941 0,10777936 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03157941 0,10758014 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03157941 0,10738165 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03157941 0,10718389 ! neuron recognition GO:0008038 5 5 0,000 0,03157941 0,10698686 ! hair follicle maturation GO:0048820 5 5 0,000 0,03157941 0,10679056 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03157941 0,10659497 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03157941 0,1064001 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03157941 0,10620594 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03157941 0,10601248 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03157941 0,10581973 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03157941 0,10562768 ! postreplication repair GO:0006301 5 5 0,000 0,03157941 0,10543633 ! cellular pigmentation GO:0033059 5 5 0,000 0,03157941 0,10524567 ! histone methylation GO:0016571 5 5 0,000 0,03157941 0,10505569 ! DNA methylation GO:0006306 5 5 0,000 0,03157941 0,1048664 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03157941 0,10467779 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03157941 0,10448986 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03157941 0,10430261 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03157941 0,10411602 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03157941 0,1039301 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03157941 0,10374484 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03157941 0,10356024 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03157941 0,10337629 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03157941 0,103193 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03157941 0,10301036 ! sterol catabolic process GO:0016127 5 5 0,000 0,03157941 0,10282836 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03157941 0,10264701 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03157941 0,10246629 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03157941 0,10228621 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03157941 0,10210676 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03157941 0,10192794 ! zymogen activation GO:0031638 5 5 0,000 0,03157941 0,10174974 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03157941 0,10157217 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03157941 0,10139522 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03157941 0,10121888 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03157941 0,10104315 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03157941 0,10086803 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03157941 0,10069352 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03157941 0,10051961 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03157941 0,1003463 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03157941 0,10017359 ! NADPH regeneration GO:0006740 5 5 0,000 0,03157941 0,10000147 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03157941 0,09982994 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03157941 0,099659 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03157941 0,09948864 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03157941 0,09931886 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03157941 0,09914967 ! sarcomere organization GO:0045214 5 5 0,000 0,03157941 0,09898104 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03157941 0,09881299 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03157941 0,09864551 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03157941 0,0984786 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03157941 0,09831225 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03157941 0,09814647 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03157941 0,09798124 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03157941 0,09781656 ! spleen development GO:0048536 5 5 0,000 0,03157941 0,09765244 ! male genitalia development GO:0030539 5 5 0,000 0,03157941 0,09748887 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03157941 0,09732584 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03157941 0,09716336 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03157941 0,09700142 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03157941 0,09684002 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03157941 0,09667916 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03157941 0,09651883 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03157941 0,09635903 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03157941 0,09619976 ! ATP catabolic process GO:0006200 5 5 0,000 0,03157941 0,09604101 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03157941 0,09588279 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03157941 0,09572509 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03157941 0,0955679 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03157941 0,09541124 ! activation of innate immune response GO:0002218 5 5 0,000 0,03157941 0,09525508 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03157941 0,09509943 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03157941 0,0949443 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03157941 0,09478966 ! muscle adaptation GO:0043500 5 5 0,000 0,03157941 0,09463553 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03157941 0,09448191 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03157941 0,09432877 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03157941 0,09417614 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03157941 0,094024 ! defense response to fungus GO:0050832 5 5 0,000 0,03157941 0,09387234 ! lysogeny GO:0030069 5 5 0,000 0,03157941 0,09372118 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03157941 0,0935705 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03157941 0,09342031 ! response to nicotine GO:0035094 5 5 0,000 0,03157941 0,0932706 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03157941 0,09312137 ! mitochondrion localization GO:0051646 5 5 0,000 0,03157941 0,09297261 ! nucleus localization GO:0051647 5 5 0,000 0,03157941 0,09282433 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03157941 0,09267652 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,03190945 0,0934962 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03190945 0,0933478 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,03326004 0,09714461 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,03326004 0,0969909 ! tube morphogenesis GO:0035239 47 46 1,000 0,03463283 0,10083461 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,03463283 0,10067557 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,03463283 0,10051702 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,03463283 0,10035898 ! regulation of membrane potential GO:0042391 46 46 1,000 0,03463283 0,10020143 ! actin filament organization GO:0007015 50 48 1,000 0,03744375 0,10816431 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,03744375 0,10799504 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,03744375 0,1078263 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,0377773 0,10861711 ! axon extension GO:0048675 7 6 0,000 0,0377773 0,10844793 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,0377773 0,10827927 ! tRNA modification GO:0006400 6 6 0,000 0,0377773 0,10811113 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,0377773 0,10794352 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,0377773 0,10777642 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,0377773 0,10760984 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,0377773 0,10744378 ! regulation of S phase GO:0033261 6 6 0,000 0,0377773 0,10727823 ! myotube differentiation GO:0014902 6 6 0,000 0,0377773 0,10711318 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,0377773 0,10694865 ! bone remodeling GO:0046849 6 6 0,000 0,0377773 0,10678461 ! N-glycan processing GO:0006491 6 6 0,000 0,0377773 0,10662108 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,0377773 0,10645806 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,0377773 0,10629552 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,0377773 0,10613349 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,0377773 0,10597195 ! RNA methylation GO:0001510 6 6 0,000 0,0377773 0,10581089 ! cartilage condensation GO:0001502 7 6 0,000 0,0377773 0,10565033 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,0377773 0,10549026 ! succinate metabolic process GO:0006105 7 6 0,000 0,0377773 0,10533066 ! artery development GO:0060840 6 6 0,000 0,0377773 0,10517155 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,0377773 0,10501292 ! bile acid metabolic process GO:0008206 6 6 0,000 0,0377773 0,10485477 ! androgen metabolic process GO:0008209 6 6 0,000 0,0377773 0,1046971 ! estrogen metabolic process GO:0008210 6 6 0,000 0,0377773 0,10453989 ! limbic system development GO:0021761 7 6 0,000 0,0377773 0,10438316 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,0377773 0,1042269 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,0377773 0,1040711 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,0377773 0,10391577 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,0377773 0,10376091 ! pathogenesis GO:0009405 6 6 0,000 0,0377773 0,1036065 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,0377773 0,10345255 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,0377773 0,10329906 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,0377773 0,10314603 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,0377773 0,10299344 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,0377773 0,10284131 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,0377773 0,10268963 ! arginine metabolic process GO:0006525 6 6 0,000 0,0377773 0,10253839 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,0377773 0,1023876 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,0377773 0,10223725 ! glutamate catabolic process GO:0006538 7 6 0,000 0,0377773 0,10208734 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,0377773 0,10193787 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,0377773 0,10178884 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,0377773 0,10164025 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,0377773 0,10149208 ! V(D)J recombination GO:0033151 6 6 0,000 0,0377773 0,10134435 ! focal adhesion formation GO:0048041 7 6 0,000 0,0377773 0,10119705 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,0377773 0,10105017 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,0377773 0,10090372 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,0377773 0,1007577 ! regulation of heart rate GO:0002027 6 6 0,000 0,0377773 0,10061209 ! asymmetric protein localization GO:0008105 6 6 0,000 0,0377773 0,10046691 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,0377773 0,10032214 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,0377773 0,1001778 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,0377773 0,10003386 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,0377773 0,09989034 ! ruffle organization GO:0031529 6 6 0,000 0,0377773 0,09974723 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,0377773 0,09960453 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,0377773 0,09946224 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,0377773 0,09932035 ! neutral amino acid transport GO:0015804 6 6 0,000 0,0377773 0,09917887 ! L-amino acid transport GO:0015807 6 6 0,000 0,0377773 0,09903779 ! bone mineralization GO:0030282 6 6 0,000 0,0377773 0,09889711 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,0377773 0,09875683 ! negative regulation of ossification GO:0030279 6 6 0,000 0,0377773 0,09861695 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,0377773 0,09847747 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,0377773 0,09833837 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,0377773 0,09819967 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,0377773 0,09806136 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,0377773 0,09792344 ! regulation of organ growth GO:0046620 6 6 0,000 0,0377773 0,09778591 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,0377773 0,09764876 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,0377773 0,097512 ! response to dsRNA GO:0043331 6 6 0,000 0,0377773 0,09737562 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,0377773 0,09723962 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,0377773 0,097104 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,0377773 0,09696876 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,0377773 0,09683389 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,0377773 0,0966994 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,0377773 0,09656528 ! multicellular organismal aging GO:0010259 6 6 0,000 0,0377773 0,09643154 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,0377773 0,09629816 ! erythrocyte development GO:0048821 6 6 0,000 0,0377773 0,09616515 ! renal water homeostasis GO:0003091 6 6 0,000 0,0377773 0,09603251 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,0377773 0,09590023 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,0377773 0,09576832 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,0377773 0,09563677 ! ribosome assembly GO:0042255 6 6 0,000 0,0377773 0,09550558 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,0377773 0,09537475 ! diencephalon development GO:0021536 6 6 0,000 0,0377773 0,09524428 ! fucose catabolic process GO:0019317 6 6 0,000 0,0377773 0,09511416 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,0377773 0,0949844 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,0377773 0,094855 ! regulation of lipid transport GO:0032368 6 6 0,000 0,0377773 0,09472594 ! regulation of cell division GO:0051302 6 6 0,000 0,0377773 0,09459724 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,0377773 0,09446889 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,0377773 0,09434088 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,0377773 0,09421322 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,0377773 0,0940859 ! neuroblast proliferation GO:0007405 6 6 0,000 0,0377773 0,09395893 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,0377773 0,0938323 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,0377773 0,09370601 ! regulation of glucose transport GO:0010827 6 6 0,000 0,0377773 0,09358007 GO:0046324|regulation of glucose import, ! methionine biosynthetic process GO:0009086 6 6 0,000 0,0377773 0,09345445 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,0377773 0,09332918 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,0377773 0,09320424 ! lymph node development GO:0048535 6 6 0,000 0,0377773 0,09307964 ! organic cation transport GO:0015695 6 6 0,000 0,0377773 0,09295536 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,0377773 0,09283142 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,0377773 0,09270781 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,0377773 0,09258453 ! sperm-egg recognition GO:0035036 7 6 0,000 0,0377773 0,09246158 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,0377773 0,09233895 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,0377773 0,09221665 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,0377773 0,09209467 ! alditol metabolic process GO:0019400 6 6 0,000 0,0377773 0,09197301 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,0377773 0,09185167 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,0377773 0,09173066 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,0377773 0,09160996 ! regulation of ligase activity GO:0051340 50 49 1,000 0,03888123 0,09416309 ! regulation of defense response GO:0031347 50 50 1,000 0,04033964 0,09756686 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,04033964 0,09743899 ! transcription initiation GO:0006352 50 50 1,000 0,04033964 0,09731145 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,04033964 0,09718425 ! positive regulation of immune response GO:0050778 51 51 1,000 0,04181865 0,1006159 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,04181865 0,10048472 GO:0051325|interphase, ! cholesterol metabolic process GO:0008203 52 52 1,000 0,04331797 0,10395185 ! respiratory burst GO:0045730 7 7 0,000 0,04393642 0,10529887 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04393642 0,10516212 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04393642 0,10502572 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04393642 0,10488967 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04393642 0,10475398 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04393642 0,10461864 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04393642 0,10448365 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04393642 0,10434901 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04393642 0,10421471 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04393642 0,10408076 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04393642 0,10394715 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04393642 0,10381388 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04393642 0,10368096 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04393642 0,10354837 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04393642 0,10341613 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04393642 0,10328422 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04393642 0,10315265 ! axis specification GO:0009798 7 7 0,000 0,04393642 0,10302141 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04393642 0,10289051 ! visual behavior GO:0007632 7 7 0,000 0,04393642 0,10275993 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04393642 0,10262969 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04393642 0,10249978 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04393642 0,1023702 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04393642 0,10224095 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04393642 0,10211202 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04393642 0,10198341 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04393642 0,10185513 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04393642 0,10172717 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04393642 0,10159953 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04393642 0,10147222 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04393642 0,10134522 ! protein targeting to ER GO:0045047 8 7 0,000 0,04393642 0,10121854 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04393642 0,10109217 ! endoderm development GO:0007492 7 7 0,000 0,04393642 0,10096612 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04393642 0,10084038 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04393642 0,10071496 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04393642 0,10058985 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04393642 0,10046505 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04393642 0,10034056 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04393642 0,10021637 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04393642 0,1000925 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04393642 0,09996892 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04393642 0,09984566 ! UV protection GO:0009650 7 7 0,000 0,04393642 0,0997227 ! DNA integration GO:0015074 7 7 0,000 0,04393642 0,09960004 ! myofibril assembly GO:0030239 7 7 0,000 0,04393642 0,09947768 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04393642 0,09935562 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04393642 0,09923386 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04393642 0,0991124 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04393642 0,09899123 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04393642 0,09887036 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04393642 0,09874979 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04393642 0,09862951 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04393642 0,09850952 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04393642 0,09838983 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04393642 0,09827042 ! axon cargo transport GO:0008088 7 7 0,000 0,04393642 0,09815131 ! eating behavior GO:0042755 7 7 0,000 0,04393642 0,09803248 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04393642 0,09791394 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04393642 0,09779569 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04393642 0,09767772 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04393642 0,09756003 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04393642 0,09744263 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04393642 0,09732552 ! induction of an organ GO:0001759 7 7 0,000 0,04393642 0,09720868 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04393642 0,09709212 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04393642 0,09697584 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04393642 0,09685984 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04393642 0,09674412 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04393642 0,09662867 ! platelet activation GO:0030168 8 7 0,000 0,04393642 0,0965135 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04393642 0,09639861 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04393642 0,09628398 ! natural killer cell activation GO:0030101 7 7 0,000 0,04393642 0,09616963 ! NADP metabolic process GO:0006739 7 7 0,000 0,04393642 0,09605555 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04393642 0,09594174 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04393642 0,0958282 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04393642 0,09571493 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04393642 0,09560192 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04393642 0,09548918 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04393642 0,09537671 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04393642 0,0952645 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04393642 0,09515256 ! cell-cell recognition GO:0009988 8 7 0,000 0,04393642 0,09504088 ! hormone catabolic process GO:0042447 7 7 0,000 0,04393642 0,09492946 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04393642 0,0948183 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04393642 0,0947074 ! oxygen transport GO:0015671 7 7 0,000 0,04393642 0,09459676 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04393642 0,09448638 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04393642 0,09437626 ! regulation of axon extension GO:0030516 7 7 0,000 0,04393642 0,09426639 ! cell killing GO:0001906 7 7 0,000 0,04393642 0,09415678 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04393642 0,09404742 ! adult feeding behavior GO:0008343 7 7 0,000 0,04393642 0,09393832 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04393642 0,09382947 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04393642 0,09372087 ! response to cold GO:0009409 7 7 0,000 0,04393642 0,09361252 ! regulation of T cell activation GO:0050863 53 53 1,000 0,04483729 0,09542162 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,04637629 0,09858305 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,04637629 0,09846948 ! reproductive developmental process GO:0003006 56 56 1,000 0,04951217 0,10500683 ! regulation of nervous system development GO:0051960 57 56 1,000 0,04951217 0,10488613 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05005701 0,10591857 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05005701 0,1057971 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05005701 0,10567591 ! positive regulation of translation GO:0045727 8 8 0,000 0,05005701 0,105555 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05005701 0,10543437 ! superoxide anion generation GO:0042554 8 8 0,000 0,05005701 0,10531401 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05005701 0,10519392 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05005701 0,10507411 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05005701 0,10495457 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05005701 0,10483531 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05005701 0,10471631 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05005701 0,10459759 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05005701 0,10447913 ! zinc ion transport GO:0006829 8 8 0,000 0,05005701 0,10436094 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05005701 0,10424302 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05005701 0,10412536 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05005701 0,10400797 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05005701 0,10389085 ! lipid localization GO:0010876 8 8 0,000 0,05005701 0,10377398 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05005701 0,10365738 ! response to cAMP GO:0051591 8 8 0,000 0,05005701 0,10354105 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05005701 0,10342497 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05005701 0,10330915 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05005701 0,10319359 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05005701 0,10307829 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05005701 0,10296325 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05005701 0,10284846 ! sensory perception of taste GO:0050909 8 8 0,000 0,05005701 0,10273393 ! organelle fusion GO:0048284 8 8 0,000 0,05005701 0,10261966 ! pancreas development GO:0031016 8 8 0,000 0,05005701 0,10250563 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05005701 0,10239187 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05005701 0,10227835 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05005701 0,10216508 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05005701 0,10205207 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05005701 0,10193931 ! sperm motility GO:0030317 8 8 0,000 0,05005701 0,10182679 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05005701 0,10171452 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05005701 0,1016025 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05005701 0,10149073 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05005701 0,1013792 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05005701 0,10126792 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05005701 0,10115688 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05005701 0,10104608 ! Golgi organization GO:0007030 8 8 0,000 0,05005701 0,10093553 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05005701 0,10082521 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05005701 0,10071514 ! fructose metabolic process GO:0006000 8 8 0,000 0,05005701 0,10060531 ! mannose metabolic process GO:0006013 9 8 0,000 0,05005701 0,10049572 ! NAD metabolic process GO:0019674 8 8 0,000 0,05005701 0,10038637 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05005701 0,10027725 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05005701 0,10016837 ! response to fungus GO:0009620 8 8 0,000 0,05005701 0,10005973 ! stem cell differentiation GO:0048863 8 8 0,000 0,05005701 0,09995132 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05005701 0,09984315 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05005701 0,09973521 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05005701 0,09962751 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05005701 0,09952003 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05005701 0,09941279 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05005701 0,09930578 ! vasoconstriction GO:0042310 8 8 0,000 0,05005701 0,099199 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05005701 0,09909245 ! muscle cell development GO:0055001 8 8 0,000 0,05005701 0,09898613 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05005701 0,09888003 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05005701 0,09877417 ! sensory perception of pain GO:0019233 8 8 0,000 0,05005701 0,09866853 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05005701 0,09856311 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05005701 0,09845792 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05005701 0,09835295 ! chromatin silencing GO:0006342 8 8 0,000 0,05005701 0,09824821 ! tissue regeneration GO:0042246 8 8 0,000 0,05005701 0,09814369 ! salivary gland development GO:0007431 8 8 0,000 0,05005701 0,0980394 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05005701 0,09793532 ! T cell homeostasis GO:0043029 8 8 0,000 0,05005701 0,09783146 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05005701 0,09772783 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,05005701 0,09762441 ! water homeostasis GO:0030104 8 8 0,000 0,05005701 0,09752122 ! cofactor transport GO:0051181 8 8 0,000 0,05005701 0,09741824 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05005701 0,09731548 ! acid secretion GO:0046717 8 8 0,000 0,05005701 0,09721293 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05005701 0,0971106 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05005701 0,09700849 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05005701 0,09690659 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05005701 0,0968049 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05005701 0,09670343 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05005701 0,09660217 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05005701 0,09650112 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05005701 0,09640028 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05005701 0,09629966 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05005701 0,09619924 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05005701 0,09609903 ! developmental induction GO:0031128 8 8 0,000 0,05005701 0,09599903 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05005701 0,09589924 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05005701 0,09579966 ! actin filament polymerization GO:0030041 9 8 0,000 0,05005701 0,09570028 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05005701 0,09560111 ! peptide hormone processing GO:0016486 8 8 0,000 0,05005701 0,09550214 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05005701 0,09540338 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05005701 0,09530483 ! dephosphorylation GO:0016311 60 59 1,000 0,05435624 0,10338344 ! regulation of cell development GO:0060284 60 59 1,000 0,05435624 0,10327686 ! sterol metabolic process GO:0016125 59 59 1,000 0,05435624 0,1031705 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,05600717 0,10619466 ! protein polymerization GO:0051258 65 60 1,000 0,05600717 0,10608552 ! lactation GO:0007595 10 9 0,000 0,0561393 0,10622662 ! embryonic pattern specification GO:0009880 10 9 0,000 0,0561393 0,10611767 ! positive regulation of cell size GO:0045793 9 9 0,000 0,0561393 0,10600894 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,0561393 0,10590044 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,0561393 0,10579216 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,0561393 0,1056841 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,0561393 0,10557626 ! viral genome replication GO:0019079 9 9 0,000 0,0561393 0,10546863 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,0561393 0,10536123 ! copper ion transport GO:0006825 9 9 0,000 0,0561393 0,10525405 ! lipid phosphorylation GO:0046834 9 9 0,000 0,0561393 0,10514708 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,0561393 0,10504034 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,0561393 0,1049338 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,0561393 0,10482749 ! RNA polyadenylation GO:0043631 9 9 0,000 0,0561393 0,10472139 GO:0006378|mRNA polyadenylation, ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,0561393 0,1046155 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,0561393 0,10450983 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,0561393 0,10440437 ! phospholipid efflux GO:0033700 9 9 0,000 0,0561393 0,10429912 ! response to alkaloid GO:0043279 10 9 0,000 0,0561393 0,10419409 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,0561393 0,10408927 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,0561393 0,10398465 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,0561393 0,10388025 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,0561393 0,10377606 ! response to ethanol GO:0045471 9 9 0,000 0,0561393 0,10367207 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,0561393 0,1035683 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,0561393 0,10346473 ! methionine metabolic process GO:0006555 9 9 0,000 0,0561393 0,10336137 ! glutamine metabolic process GO:0006541 9 9 0,000 0,0561393 0,10325821 ! cerebral cortex development GO:0021987 9 9 0,000 0,0561393 0,10315526 ! response to osmotic stress GO:0006970 9 9 0,000 0,0561393 0,10305252 ! pigmentation during development GO:0048066 9 9 0,000 0,0561393 0,10294998 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,0561393 0,10284764 ! central nervous system neuron development GO:0021954 10 9 0,000 0,0561393 0,10274551 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,0561393 0,10264358 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,0561393 0,10254185 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,0561393 0,10244033 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,0561393 0,102339 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,0561393 0,10223788 ! L-glutamate transport GO:0015813 9 9 0,000 0,0561393 0,10213695 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,0561393 0,10203622 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,0561393 0,10193569 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,0561393 0,10183536 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,0561393 0,10173523 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,0561393 0,10163529 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,0561393 0,10153555 ! DNA replication initiation GO:0006270 9 9 0,000 0,0561393 0,10143601 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,0561393 0,10133666 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,0561393 0,10123751 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,0561393 0,10113854 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,0561393 0,10103978 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,0561393 0,1009412 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,0561393 0,10084282 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,0561393 0,10074463 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,0561393 0,10064662 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,0561393 0,10054881 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,0561393 0,10045119 ! collagen catabolic process GO:0030574 9 9 0,000 0,0561393 0,10035376 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,0561393 0,10025652 ! purine base metabolic process GO:0006144 9 9 0,000 0,0561393 0,10015947 ! gas transport GO:0015669 9 9 0,000 0,0561393 0,1000626 ! cholesterol efflux GO:0033344 9 9 0,000 0,0561393 0,09996592 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,0561393 0,09986943 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,0561393 0,09977312 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,0561393 0,099677 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,0561393 0,09958107 ! defense response to virus GO:0051607 9 9 0,000 0,0561393 0,09948532 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,0561393 0,09938975 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,0561393 0,09929437 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,05767574 0,10191408 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,05767574 0,10181646 ! axonogenesis GO:0007409 66 62 1,000 0,05936167 0,1046924 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,05936167 0,10459231 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,05936167 0,10449241 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06218353 0,10935519 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06218353 0,10925094 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06218353 0,10914689 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06218353 0,10904304 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06218353 0,10893939 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06218353 0,10883593 ! neuron maturation GO:0042551 10 10 0,000 0,06218353 0,10873267 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06218353 0,10862961 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06218353 0,10852674 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06218353 0,10842407 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06218353 0,10832159 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06218353 0,1082193 ! hormone secretion GO:0046879 10 10 0,000 0,06218353 0,1081172 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06218353 0,1080153 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06218353 0,10791359 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! cAMP metabolic process GO:0046058 10 10 0,000 0,06218353 0,10781208 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06218353 0,10771075 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06218353 0,10760961 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06218353 0,10750867 ! glial cell development GO:0021782 10 10 0,000 0,06218353 0,10740791 ! phototransduction GO:0007602 11 10 0,000 0,06218353 0,10730734 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,06218353 0,10720696 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06218353 0,10710676 ! fat cell differentiation GO:0045444 10 10 0,000 0,06218353 0,10700676 ! myoblast differentiation GO:0045445 10 10 0,000 0,06218353 0,10690694 ! centrosome cycle GO:0007098 10 10 0,000 0,06218353 0,1068073 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06218353 0,10670786 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06218353 0,10660859 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06218353 0,10650951 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06218353 0,10641062 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06218353 0,10631191 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06218353 0,10621338 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06218353 0,10611503 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06218353 0,10601687 ! plasma membrane organization GO:0007009 10 10 0,000 0,06218353 0,10591889 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06218353 0,10582109 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,06218353 0,10572347 ! lysosomal transport GO:0007041 10 10 0,000 0,06218353 0,10562603 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06218353 0,10552876 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06218353 0,10543168 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06218353 0,10533478 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06218353 0,10523805 ! exocrine system development GO:0035272 10 10 0,000 0,06218353 0,1051415 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06218353 0,10504513 ! embryo implantation GO:0007566 11 10 0,000 0,06218353 0,10494894 ! regulation of protein binding GO:0043393 11 10 0,000 0,06218353 0,10485292 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06218353 0,10475707 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06218353 0,1046614 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06218353 0,10456591 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,06218353 0,10447059 ! protein export from nucleus GO:0006611 10 10 0,000 0,06218353 0,10437544 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06218353 0,10428047 ! cytolysis GO:0019835 10 10 0,000 0,06218353 0,10418567 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06218353 0,10409104 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06218353 0,10399659 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06218353 0,1039023 ! histone deacetylation GO:0016575 10 10 0,000 0,06218353 0,10380819 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06218353 0,10371424 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06218353 0,10362047 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06218353 0,10352686 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06218353 0,10343343 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06218353 0,10334016 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06218353 0,10324706 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06218353 0,10315413 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06218353 0,10306136 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06218353 0,10296877 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06218353 0,10287633 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06218353 0,10278407 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06218353 0,10269197 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06218353 0,10260003 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06218353 0,10250826 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06218353 0,10241666 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06218353 0,10232521 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06218353 0,10223393 ! protein stabilization GO:0050821 10 10 0,000 0,06218353 0,10214281 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,0627845 0,10303814 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,0627845 0,10294647 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,0627845 0,10285496 ! protein amino acid glycosylation GO:0006486 66 66 1,000 0,06627346 0,10847424 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,06627346 0,10837799 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,06804207 0,11117158 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Ras protein signal transduction GO:0007265 69 67 1,000 0,06804207 0,11107311 ! protein secretion GO:0009306 11 11 0,000 0,06818992 0,11121595 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06818992 0,11111761 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06818992 0,11101945 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,06818992 0,11092147 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06818992 0,11082365 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06818992 0,11072601 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06818992 0,11062854 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06818992 0,11053124 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06818992 0,11043411 ! skin development GO:0043588 11 11 0,000 0,06818992 0,11033716 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06818992 0,11024037 ! signal complex assembly GO:0007172 11 11 0,000 0,06818992 0,11014375 ! microtubule-based transport GO:0010970 11 11 0,000 0,06818992 0,1100473 ! peroxisomal transport GO:0043574 11 11 0,000 0,06818992 0,10995102 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06818992 0,10985491 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06818992 0,10975897 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06818992 0,10966319 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,06818992 0,10956759 ! T cell proliferation GO:0042098 11 11 0,000 0,06818992 0,10947214 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06818992 0,10937687 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06818992 0,10928176 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,06818992 0,10918681 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06818992 0,10909203 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06818992 0,10899742 ! mitotic spindle organization GO:0007052 11 11 0,000 0,06818992 0,10890296 ! fucose metabolic process GO:0006004 11 11 0,000 0,06818992 0,10880868 ! membrane budding GO:0006900 11 11 0,000 0,06818992 0,10871455 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,06818992 0,10862059 ! monoamine transport GO:0015844 11 11 0,000 0,06818992 0,10852679 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06818992 0,10843315 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06818992 0,10833967 ! body fluid secretion GO:0007589 11 11 0,000 0,06818992 0,10824636 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06818992 0,1081532 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06818992 0,10806021 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06818992 0,10796737 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,06818992 0,1078747 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06818992 0,10778218 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06818992 0,10768982 ! oogenesis GO:0048477 11 11 0,000 0,06818992 0,10759762 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06818992 0,10750558 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06818992 0,10741369 ! vitamin transport GO:0051180 11 11 0,000 0,06818992 0,10732196 ! muscle maintenance GO:0046716 12 11 0,000 0,06818992 0,10723039 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06818992 0,10713898 ! hindbrain development GO:0030902 11 11 0,000 0,06818992 0,10704772 ! steroid catabolic process GO:0006706 11 11 0,000 0,06818992 0,10695661 ! endocrine process GO:0050886 11 11 0,000 0,06818992 0,10686566 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06818992 0,10677487 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06818992 0,10668423 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06818992 0,10659374 ! regulation of cell size GO:0008361 68 68 1,000 0,06982641 0,10905938 ! regulation of translation GO:0006417 69 69 1,000 0,07162621 0,11177571 ! response to nutrient levels GO:0031667 69 69 1,000 0,07162621 0,11168114 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,07162621 0,11158674 ! positive regulation of transport GO:0051050 71 70 1,000 0,07344122 0,11431771 ! cell part morphogenesis GO:0032990 75 70 1,000 0,07344122 0,11422124 ! wound healing GO:0042060 74 70 1,000 0,07344122 0,11412494 ! growth GO:0040007 70 70 1,000 0,07344122 0,11402879 ! translational initiation GO:0006413 12 12 0,000 0,07415871 0,11504588 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,07415871 0,11494912 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07415871 0,11485253 ! initiation of viral infection GO:0019059 12 12 0,000 0,07415871 0,11475609 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07415871 0,11465982 ! iron ion transport GO:0006826 13 12 0,000 0,07415871 0,11456371 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07415871 0,11446776 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07415871 0,11437197 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07415871 0,11427634 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07415871 0,11418088 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,07415871 0,11408557 ! collagen metabolic process GO:0032963 12 12 0,000 0,07415871 0,11399041 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07415871 0,11389542 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,07415871 0,11380059 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,07415871 0,11370591 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,07415871 0,11361139 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,07415871 0,11351703 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07415871 0,11342283 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07415871 0,11332878 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07415871 0,11323489 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,07415871 0,11314115 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07415871 0,11304757 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07415871 0,11295414 GO:0016101|diterpenoid metabolic process, ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07415871 0,11286086 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07415871 0,11276775 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,07415871 0,11267478 ! acute-phase response GO:0006953 12 12 0,000 0,07415871 0,11258197 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07415871 0,11248931 ! vacuolar transport GO:0007034 12 12 0,000 0,07415871 0,1123968 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07415871 0,11230444 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07415871 0,11221224 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07415871 0,11212019 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07415871 0,11202828 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,07415871 0,11193653 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07415871 0,11184493 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,07415871 0,11175348 ! renal system process GO:0003014 12 12 0,000 0,07415871 0,11166218 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07415871 0,11157103 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07415871 0,11148002 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07415871 0,11138917 ! pallium development GO:0021543 13 12 0,000 0,07415871 0,11129846 ! cell fate determination GO:0001709 12 12 0,000 0,07415871 0,1112079 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,07415871 0,11111749 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,07415871 0,11102722 ! G1 phase GO:0051318 13 12 0,000 0,07415871 0,1109371 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07415871 0,11084713 ! detection of light stimulus GO:0009583 13 12 0,000 0,07415871 0,1107573 ! synaptogenesis GO:0007416 12 12 0,000 0,07415871 0,11066762 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07415871 0,11057808 ! hormone transport GO:0009914 12 12 0,000 0,07415871 0,11048869 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07415871 0,11039944 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07415871 0,11031034 ! spermatid differentiation GO:0048515 13 12 0,000 0,07415871 0,11022138 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,07415871 0,11013256 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07415871 0,11004389 ! neural tube closure GO:0001843 13 12 0,000 0,07415871 0,10995536 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,07415871 0,10986697 ! translational elongation GO:0006414 71 71 1,000 0,07527118 0,11142553 ! regulation of cell activation GO:0050865 71 71 1,000 0,07527118 0,1113361 ! sensory organ development GO:0007423 72 72 1,000 0,07711583 0,11397312 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,07711583 0,11388179 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08009014 0,11817944 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08009014 0,1180849 ! phenol metabolic process GO:0018958 13 13 0,000 0,08009014 0,1179905 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,08009014 0,11789626 ! gluconeogenesis GO:0006094 13 13 0,000 0,08009014 0,11780217 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08009014 0,11770823 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08009014 0,11761444 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08009014 0,1175208 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08009014 0,1174273 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08009014 0,11733396 ! regeneration GO:0031099 13 13 0,000 0,08009014 0,11724076 ! keratinization GO:0031424 13 13 0,000 0,08009014 0,11714772 ! post-embryonic development GO:0009791 14 13 0,000 0,08009014 0,11705481 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08009014 0,11696206 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08009014 0,11686945 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08009014 0,11677699 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08009014 0,11668468 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08009014 0,11659251 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,08009014 0,11650049 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08009014 0,11640861 ! autophagy GO:0006914 13 13 0,000 0,08009014 0,11631688 ! receptor metabolic process GO:0043112 14 13 0,000 0,08009014 0,11622529 ! actin filament bundle formation GO:0051017 13 13 0,000 0,08009014 0,11613385 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,08009014 0,11604255 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08009014 0,11595139 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08009014 0,11586038 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08009014 0,11576951 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08009014 0,11567878 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08009014 0,11558819 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08009014 0,11549775 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08009014 0,11540744 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08009014 0,11531728 ! vasodilation GO:0042311 14 13 0,000 0,08009014 0,11522726 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08009014 0,11513738 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08009014 0,11504764 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08009014 0,11495804 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,08009014 0,11486858 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08009014 0,11477925 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08009014 0,11469007 ! immunoglobulin production GO:0002377 13 13 0,000 0,08009014 0,11460103 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08009014 0,11451212 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08009014 0,11442335 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08009014 0,11433472 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08009014 0,11424622 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08009014 0,11415787 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08009014 0,11406965 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08009014 0,11398156 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08009014 0,11389361 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08009014 0,1138058 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08009014 0,11371812 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08009014 0,11363058 ! telomere organization GO:0032200 13 13 0,000 0,08009014 0,11354317 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08009014 0,1134559 ! regulation of amine transport GO:0051952 13 13 0,000 0,08009014 0,11336876 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08009014 0,11328175 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08598442 0,12152552 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08598442 0,1214324 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08598442 0,12133942 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08598442 0,12124658 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08598442 0,12115389 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08598442 0,12106133 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08598442 0,12096892 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,08598442 0,12087665 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08598442 0,12078451 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08598442 0,12069252 ! vesicle docking GO:0048278 14 14 0,000 0,08598442 0,12060067 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08598442 0,12050896 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08598442 0,12041739 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08598442 0,12032595 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08598442 0,12023466 ! hair cycle GO:0042633 14 14 0,000 0,08598442 0,1201435 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08598442 0,12005249 ! response to retinoic acid GO:0032526 14 14 0,000 0,08598442 0,11996161 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08598442 0,11987086 ! lysosome organization GO:0007040 14 14 0,000 0,08598442 0,11978026 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08598442 0,11968979 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08598442 0,11959946 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,08598442 0,11950926 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,08598442 0,1194192 ! primary neural tube formation GO:0014020 15 14 0,000 0,08598442 0,11932928 ! peptide cross-linking GO:0018149 14 14 0,000 0,08598442 0,11923949 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08598442 0,11914984 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08598442 0,11906032 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08598442 0,11897093 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08598442 0,11888168 ! DNA modification GO:0006304 14 14 0,000 0,08598442 0,11879257 ! collagen fibril organization GO:0030199 14 14 0,000 0,08598442 0,11870358 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08598442 0,11861473 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,08598442 0,11852602 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08598442 0,11843743 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08598442 0,11834898 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08598442 0,11826066 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08598442 0,11817247 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08598442 0,11808441 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,08598442 0,11799649 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08598442 0,11790869 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,08655073 0,11859703 ! regulation of protein modification process GO:0031399 79 78 1,000 0,08847833 0,12114826 ! microtubule-based movement GO:0007018 82 78 1,000 0,08847833 0,12105832 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,09184179 0,12556707 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09184179 0,12547399 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09184179 0,12538105 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,09184179 0,12528824 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09184179 0,12519557 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09184179 0,12510304 ! response to vitamin GO:0033273 15 15 0,000 0,09184179 0,12501064 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,09184179 0,12491838 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,09184179 0,12482626 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09184179 0,12473427 ! ovarian follicle development GO:0001541 15 15 0,000 0,09184179 0,12464242 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09184179 0,12455071 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09184179 0,12445913 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09184179 0,12436768 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09184179 0,12427637 ! heme metabolic process GO:0042168 15 15 0,000 0,09184179 0,12418519 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09184179 0,12409414 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09184179 0,12400323 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09184179 0,12391245 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09184179 0,12382181 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09184179 0,12373129 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09184179 0,12364091 ! phospholipid transport GO:0015914 15 15 0,000 0,09184179 0,12355066 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,09184179 0,12346055 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09184179 0,12337056 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09184179 0,12328071 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09184179 0,12319098 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,09184179 0,12310139 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,09184179 0,12301193 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09184179 0,12292259 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,09184179 0,12283339 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09184179 0,12274432 ! protein homooligomerization GO:0051260 15 15 0,000 0,09184179 0,12265537 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09184179 0,12256655 ! glycoprotein biosynthetic process GO:0009101 80 80 1,000 0,09237221 0,12318522 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,09766246 0,130146 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,09766246 0,13005197 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,09766246 0,12995807 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,09766246 0,1298643 ! learning GO:0007612 16 16 0,000 0,09766246 0,12977067 ! circadian rhythm GO:0007623 16 16 0,000 0,09766246 0,12967718 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09766246 0,12958382 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,09766246 0,12949059 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,09766246 0,1293975 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,09766246 0,12930454 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09766246 0,12921172 ! vesicle targeting GO:0006903 17 16 0,000 0,09766246 0,12911903 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,09766246 0,12902647 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,09766246 0,12893404 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09766246 0,12884175 ! positive regulation of cell development GO:0010720 16 16 0,000 0,09766246 0,12874959 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,09766246 0,12865756 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,09766246 0,12856566 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09766246 0,12847389 ! pentose metabolic process GO:0019321 16 16 0,000 0,09766246 0,12838226 ! fatty acid transport GO:0015908 16 16 0,000 0,09766246 0,12829075 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09766246 0,12819937 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,09766246 0,12810813 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09766246 0,12801701 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09766246 0,12792603 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09766246 0,12783517 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09766246 0,12774444 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09766246 0,12765385 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09766246 0,12756338 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,09766246 0,12747303 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,09766246 0,12738282 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,09766246 0,12729273 ! regulation of coagulation GO:0050818 17 16 0,000 0,09766246 0,12720277 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,1023218 0,13317732 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,10344668 0,13454639 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,10344668 0,1344515 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10344668 0,13435675 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,10344668 0,13426213 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,10344668 0,13416765 ! leukocyte adhesion GO:0007159 17 17 0,000 0,10344668 0,1340733 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,10344668 0,13397908 ! sensory perception of smell GO:0007608 17 17 0,000 0,10344668 0,13388499 ! glucose transport GO:0015758 17 17 0,000 0,10344668 0,13379104 ! cell junction assembly GO:0034329 18 17 0,000 0,10344668 0,13369722 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10344668 0,13360353 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,10344668 0,13350997 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10344668 0,13341654 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10344668 0,13332324 ! neural crest cell development GO:0014032 19 17 0,000 0,10344668 0,13323007 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,10344668 0,13313703 ! cell recognition GO:0008037 18 17 0,000 0,10344668 0,13304412 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,10344668 0,13295135 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,10344668 0,1328587 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,10344668 0,13276618 ! pigmentation GO:0043473 17 17 0,000 0,10344668 0,13267379 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,10344668 0,13258152 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10344668 0,13248939 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,10344668 0,13239738 ! liver development GO:0001889 17 17 0,000 0,10344668 0,1323055 ! gene silencing GO:0016458 17 17 0,000 0,10344668 0,13221375 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,10434675 0,1332717 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 1,000 0,10842989 0,13839078 GO:0007283|spermatogenesis, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,10919465 0,13927041 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,10919465 0,1391741 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,10919465 0,13907792 ! meiosis I GO:0007127 18 18 0,000 0,10919465 0,13898187 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,10919465 0,13888595 ! membrane docking GO:0022406 18 18 0,000 0,10919465 0,13879017 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,10919465 0,13869452 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,10919465 0,138599 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,10919465 0,13850361 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,10919465 0,13840835 ! hexose transport GO:0008645 18 18 0,000 0,10919465 0,13831323 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 18 18 0,000 0,10919465 0,13821823 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,10919465 0,13812337 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,10919465 0,13802863 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,10919465 0,13793403 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,10919465 0,13783955 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,10919465 0,13774521 ! BMP signaling pathway GO:0030509 18 18 0,000 0,10919465 0,13765099 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,10919465 0,1375569 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,10919465 0,13746294 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,10919465 0,13736911 ! brain development GO:0007420 91 90 1,000 0,11255594 0,14150109 ! DNA replication GO:0006260 91 91 1,000 0,11463452 0,14401596 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11490661 0,14425945 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11490661 0,14416125 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,11490661 0,14406318 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,11490661 0,14396525 ! feeding behavior GO:0007631 19 19 0,000 0,11490661 0,14386745 ! peroxisome organization GO:0007031 19 19 0,000 0,11490661 0,14376978 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,11490661 0,14367224 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11490661 0,14357483 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,11490661 0,14347756 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11490661 0,14338042 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,11490661 0,14328341 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11490661 0,14318653 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,11490661 0,14308978 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11490661 0,14299317 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,11490661 0,14289668 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11490661 0,14280032 ! response to heat GO:0009408 19 19 0,000 0,11490661 0,1427041 ! vesicle localization GO:0051648 20 19 0,000 0,11490661 0,142608 ! regulation of muscle development GO:0048634 21 20 0,000 0,12058277 0,14955184 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,12058277 0,14945127 ! organic ether metabolic process GO:0018904 20 20 0,000 0,12058277 0,14935083 GO:0006662|glycerol ether metabolic process, ! nucleus organization GO:0006997 20 20 0,000 0,12058277 0,14925053 ! phagocytosis GO:0006909 21 20 0,000 0,12058277 0,14915036 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,12058277 0,14905033 ! protein targeting to membrane GO:0006612 22 20 0,000 0,12058277 0,14895043 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,12058277 0,14885066 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,12058277 0,14875103 ! lipid oxidation GO:0034440 20 20 0,000 0,12058277 0,14865153 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,12058277 0,14855216 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,12058277 0,14845293 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,12058277 0,14835383 ! RNA modification GO:0009451 20 20 0,000 0,12058277 0,14825486 ! single fertilization GO:0007338 21 20 0,000 0,12058277 0,14815602 ! regulation of B cell activation GO:0050864 20 20 0,000 0,12058277 0,14805732 ! regulation of response to stress GO:0080134 97 94 1,000 0,12093 0,14838481 ! mRNA catabolic process GO:0006402 21 21 0,000 0,12622334 0,15477686 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,12622334 0,15467395 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,12622334 0,15457118 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,12622334 0,15446854 ! Notch signaling pathway GO:0007219 22 21 0,000 0,12622334 0,15436604 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,12622334 0,15426367 ! ear morphogenesis GO:0042471 21 21 0,000 0,12622334 0,15416144 ! organic anion transport GO:0015711 21 21 0,000 0,12622334 0,15405935 ! spliceosome assembly GO:0000245 22 21 0,000 0,12622334 0,15395739 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,12622334 0,15385557 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,12622334 0,15375388 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,12622334 0,15365232 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,12622334 0,1535509 ! regulation of proteolysis GO:0030162 21 21 0,000 0,12622334 0,15344962 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,12622334 0,15334846 ! endocytosis GO:0006897 99 98 1,000 0,1294558 0,15717196 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,1294558 0,15706849 ! blood circulation GO:0008015 99 98 1,000 0,1294558 0,15696515 GO:0003013|circulatory system process, ! anti-apoptosis GO:0006916 100 99 1,000 0,13160946 0,15947156 ! RNA export from nucleus GO:0006405 22 22 0,000 0,13182856 0,15963208 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,13182856 0,15952727 ! regulation of ion transport GO:0043269 22 22 0,000 0,13182856 0,15942259 ! cell junction organization GO:0034330 23 22 0,000 0,13182856 0,15931805 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,13182856 0,15921365 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,13182856 0,15910939 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,13182856 0,15900526 ! ovulation cycle process GO:0022602 22 22 0,000 0,13182856 0,15890126 ! spindle organization GO:0007051 22 22 0,000 0,13182856 0,15879741 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,13182856 0,15869369 ! cell chemotaxis GO:0060326 23 22 0,000 0,13182856 0,1585901 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,13182856 0,15848665 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,13182856 0,15838333 ! male sex differentiation GO:0046661 22 22 0,000 0,13182856 0,15828015 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,13182856 0,1581771 ! biopolymer methylation GO:0043414 22 22 0,000 0,13182856 0,15807419 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,13182856 0,15797141 ! detection of external stimulus GO:0009581 23 22 0,000 0,13182856 0,15786877 ! neuron migration GO:0001764 22 22 0,000 0,13182856 0,15776625 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,13182856 0,15766388 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,13182856 0,15756163 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,13182856 0,15745952 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,13182856 0,15735753 ! aerobic respiration GO:0009060 22 22 0,000 0,13182856 0,15725568 ! cytokine production GO:0001816 22 22 0,000 0,13182856 0,15715397 ! cytokinesis GO:0000910 23 22 0,000 0,13182856 0,15705238 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,13182856 0,15695092 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,13739863 0,16347687 ! viral infectious cycle GO:0019058 23 23 0,000 0,13739863 0,1633714 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,13739863 0,16326607 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,13739863 0,16316087 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,13739863 0,16305581 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,13739863 0,16295088 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,13739863 0,16284609 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,13739863 0,16274143 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,13739863 0,16263691 ! female gonad development GO:0008585 23 23 0,000 0,13739863 0,16253252 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,13739863 0,16242827 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,13739863 0,16232415 ! gliogenesis GO:0042063 24 24 0,000 0,14293377 0,16875524 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,14293377 0,16864721 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,14293377 0,16853931 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,14293377 0,16843154 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,14293377 0,16832392 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,14293377 0,16821643 ! ovulation cycle GO:0042698 24 24 0,000 0,14293377 0,16810908 ! fertilization GO:0009566 25 24 0,000 0,14293377 0,16800187 ! maintenance of protein location GO:0045185 25 24 0,000 0,14293377 0,1678948 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,14293377 0,16778786 ! glucan metabolic process GO:0044042 25 24 0,000 0,14293377 0,16768105 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,14843419 0,17402304 ! negative regulation of secretion GO:0051048 26 25 0,000 0,14843419 0,17391241 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,14843419 0,17380192 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,14843419 0,17369157 ! endosome transport GO:0016197 25 25 0,000 0,14843419 0,17358136 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,14843419 0,17347129 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,14843419 0,17336136 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,14843419 0,17325156 ! excretion GO:0007588 25 25 0,000 0,14843419 0,17314191 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,14843419 0,1730324 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,14843419 0,17292302 ! regulation of endocytosis GO:0030100 25 25 0,000 0,14843419 0,17281378 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,14843419 0,17270468 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,14843419 0,17259572 ! positive regulation of defense response GO:0031349 26 26 0,000 0,15390012 0,17883853 ! glycolysis GO:0006096 26 26 0,000 0,15390012 0,17872584 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,15390012 0,1786133 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,15390012 0,17850089 ! cellular defense response GO:0006968 26 26 0,000 0,15390012 0,17838863 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,15390012 0,1782765 ! regulation of protein secretion GO:0050708 26 26 0,000 0,15390012 0,17816452 ! germ cell development GO:0007281 27 26 0,000 0,15390012 0,17805268 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,15390012 0,17794097 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,15390012 0,17782941 ! maintenance of location in cell GO:0051651 27 26 0,000 0,15390012 0,17771799 ! chloride transport GO:0006821 27 27 0,000 0,15933175 0,18387502 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,15933175 0,18375996 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,15933175 0,18364503 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,15933175 0,18353026 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,15933175 0,18341562 ! peptide metabolic process GO:0006518 29 27 0,000 0,15933175 0,18330113 ! mesenchymal cell development GO:0014031 29 27 0,000 0,15933175 0,18318678 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,15933175 0,18307257 ! defense response to bacterium GO:0042742 27 27 0,000 0,15933175 0,18295851 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,15933175 0,18284459 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,15933175 0,18273081 ! cell growth GO:0016049 27 27 0,000 0,15933175 0,18261717 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,1647293 0,1886862 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,1647293 0,188569 ! carbohydrate transport GO:0008643 28 28 0,000 0,1647293 0,18845195 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,1647293 0,18833504 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,1647293 0,18821828 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,1647293 0,18810167 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,1647293 0,1879852 ! cartilage development GO:0051216 29 28 0,000 0,1647293 0,18786887 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,17009297 0,19386602 ! leukocyte migration GO:0050900 30 29 0,000 0,17009297 0,1937462 ! antigen processing and presentation GO:0019882 29 29 0,000 0,17009297 0,19362653 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,17009297 0,193507 ! tRNA processing GO:0008033 29 29 0,000 0,17009297 0,19338763 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,17009297 0,1932684 ! adult behavior GO:0030534 30 29 0,000 0,17009297 0,19314932 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,17009297 0,19303039 ! transition metal ion transport GO:0000041 31 30 0,000 0,17542298 0,19895665 ! RNA catabolic process GO:0006401 30 30 0,000 0,17542298 0,19883429 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,17542298 0,19871208 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,17542298 0,19859002 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,17542298 0,19846811 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,17542298 0,19834635 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,17542298 0,19822474 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,17542298 0,19810328 ! response to temperature stimulus GO:0009266 30 30 0,000 0,17542298 0,19798197 ! regulation of ossification GO:0030278 30 30 0,000 0,17542298 0,19786081 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,17542298 0,19773979 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,17542298 0,19761892 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,17542298 0,1974982 ! vesicle organization GO:0016050 30 30 0,000 0,17542298 0,19737763 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,17542298 0,1972572 ! establishment of organelle localization GO:0051656 31 30 0,000 0,17542298 0,19713693 ! regulation of translational initiation GO:0006446 31 31 0,000 0,18071954 0,20296533 ! membrane fusion GO:0006944 31 31 0,000 0,18071954 0,20284172 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,18071954 0,20271826 ! ion transmembrane transport GO:0034220 31 31 0,000 0,18071954 0,20259495 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,18071954 0,2024718 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,18071954 0,20234879 ! regulation of heart contraction GO:0008016 31 31 0,000 0,18071954 0,20222593 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,18071954 0,20210322 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,18071954 0,20198066 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,18071954 0,20185825 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,18071954 0,20173598 ! cell redox homeostasis GO:0045454 32 32 0,000 0,18598284 0,20748569 ! glucose catabolic process GO:0006007 32 32 0,000 0,18598284 0,20736017 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,18598284 0,2072348 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,18598284 0,20710959 ! cell maturation GO:0048469 32 32 0,000 0,18598284 0,20698452 ! nuclear export GO:0051168 32 32 0,000 0,18598284 0,20685961 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,18598284 0,20673484 ! maintenance of location GO:0051235 33 32 0,000 0,18598284 0,20661023 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,19121309 0,2122926 ! amino acid transport GO:0006865 33 33 0,000 0,19121309 0,21216479 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,19121309 0,21203714 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,19121309 0,21190963 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,19121309 0,21178228 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,19121309 0,21165509 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,19121309 0,21152804 ! regulation of actin filament length GO:0030832 34 34 0,000 0,19641049 0,21714729 ! response to metal ion GO:0010038 34 34 0,000 0,19641049 0,21701711 ! ear development GO:0043583 34 34 0,000 0,19641049 0,21688708 ! muscle cell differentiation GO:0042692 35 34 0,000 0,19641049 0,21675721 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,19641049 0,21662749 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,19641049 0,21649793 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,19641049 0,21636852 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,19641049 0,21623927 ! secondary metabolic process GO:0019748 34 34 0,000 0,19641049 0,21611017 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,19641049 0,21598123 ! detection of stimulus GO:0051606 36 34 0,000 0,19641049 0,21585244 ! acute inflammatory response GO:0002526 35 35 0,000 0,20157525 0,22139642 ! regulation of cellular component size GO:0032535 35 35 0,000 0,20157525 0,22126455 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,20157525 0,22113285 ! inorganic anion transport GO:0015698 35 35 0,000 0,20157525 0,2210013 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,20157525 0,22086991 ! hydrogen transport GO:0006818 36 36 0,000 0,20670756 0,22635891 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,20670756 0,22622449 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,20670756 0,22609023 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,20670756 0,22595613 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,20670756 0,22582219 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,20670756 0,22568841 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,20670756 0,22555479 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,20670756 0,22542133 ! gonad development GO:0008406 36 36 0,000 0,20670756 0,22528802 ! coagulation GO:0050817 39 36 0,000 0,20670756 0,22515487 GO:0007596|blood coagulation, ! meiosis GO:0007126 37 37 0,000 0,21180763 0,23057381 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,21180763 0,2304377 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,21180763 0,23030175 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,21180763 0,23016596 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,21180763 0,23003033 ! positive regulation of secretion GO:0051047 39 38 0,000 0,21687565 0,23539566 ! neurotransmitter transport GO:0006836 40 38 0,000 0,21687565 0,23525711 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,21687565 0,23511872 ! exocytosis GO:0006887 40 38 0,000 0,21687565 0,2349805 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,21687565 0,23484244 ! hexose catabolic process GO:0019320 38 38 0,000 0,21687565 0,23470454 ! RNA elongation GO:0006354 38 38 0,000 0,21687565 0,2345668 ! meiotic cell cycle GO:0051321 38 38 0,000 0,21687565 0,23442922 ! regulation of neurological system process GO:0031644 38 38 0,000 0,21687565 0,23429181 ! hemostasis GO:0007599 42 39 0,000 0,22191182 0,23959197 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,22191182 0,23945169 ! response to unfolded protein GO:0006986 39 39 0,000 0,22191182 0,23931158 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,22191182 0,23917163 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,22191182 0,23903185 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,22191182 0,23889222 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,22191182 0,23875277 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,22191182 0,23861347 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,22191182 0,23847434 ! developmental maturation GO:0021700 39 39 0,000 0,22191182 0,23833537 ! DNA catabolic process GO:0006308 41 40 0,000 0,22691634 0,24356832 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,22691634 0,24342655 ! organelle localization GO:0051640 41 40 0,000 0,22691634 0,24328494 ! amine catabolic process GO:0009310 42 41 0,000 0,23188939 0,24847218 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,23188939 0,2483278 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,23188939 0,24818359 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,23188939 0,24803955 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,23188939 0,24789567 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,23188939 0,24775197 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,23683117 0,2528852 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,23683117 0,25273877 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,23683117 0,25259251 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,23683117 0,25244642 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,23683117 0,25230049 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,23683117 0,25215474 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,23683117 0,25200915 ! reproductive structure development GO:0048608 43 43 0,000 0,24174188 0,25708614 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,24174188 0,25693788 ! alcohol catabolic process GO:0046164 43 43 0,000 0,24174188 0,25678979 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,24174188 0,25664187 ! humoral immune response GO:0006959 44 44 0,000 0,24662171 0,26167174 ! mRNA transport GO:0051028 44 44 0,000 0,24662171 0,26152118 ! vitamin metabolic process GO:0006766 44 44 0,000 0,24662171 0,26137079 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,24662171 0,26122058 ! amine biosynthetic process GO:0009309 46 45 0,000 0,25147084 0,26620376 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,25147084 0,26605095 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,25147084 0,26589831 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,25147084 0,26574584 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,25147084 0,26559355 ! protein processing GO:0016485 45 45 0,000 0,25147084 0,26544144 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,25628946 0,27037291 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,25628946 0,27021823 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,25628946 0,27006373 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,26107776 0,27495218 ! regulation of blood pressure GO:0008217 48 47 0,000 0,26107776 0,27479515 ! sex differentiation GO:0007548 47 47 0,000 0,26107776 0,27463831 ! amine transport GO:0015837 47 47 0,000 0,26107776 0,27448164 ! rhythmic process GO:0048511 47 47 0,000 0,26107776 0,27432515 ! calcium ion transport GO:0006816 48 48 0,000 0,26583593 0,2791656 ! DNA recombination GO:0006310 48 48 0,000 0,26583593 0,27900662 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,27056415 0,28380748 ! divalent metal ion transport GO:0070838 49 49 0,000 0,27056415 0,28364604 ! response to nutrient GO:0007584 49 49 0,000 0,27056415 0,28348478 ! response to bacterium GO:0009617 50 49 0,000 0,27056415 0,28332371 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,27056415 0,28316283 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,27056415 0,28300212 GO:0002696|positive regulation of leukocyte activation, ! RNA transport GO:0050658 50 50 0,000 0,27526261 0,28775326 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,27526261 0,28759013 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,27526261 0,28742719 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,27993149 0,29213689 ! rRNA metabolic process GO:0016072 51 51 0,000 0,27993149 0,29197156 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,27993149 0,29180641 ! protein maturation GO:0051604 51 51 0,000 0,27993149 0,29164146 ! RNA localization GO:0006403 52 52 0,000 0,28457097 0,29630752 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,28457097 0,29614021 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,28457097 0,29597308 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,28457097 0,29580615 ! sodium ion transport GO:0006814 53 53 0,000 0,28918124 0,30042898 ! tRNA metabolic process GO:0006399 53 53 0,000 0,28918124 0,30025973 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,28918124 0,30009066 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,28918124 0,29992179 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,28918124 0,2997531 ! response to virus GO:0009615 54 54 0,000 0,29376246 0,30433065 ! hormone metabolic process GO:0042445 55 54 0,000 0,29376246 0,30415967 ! sulfur metabolic process GO:0006790 55 54 0,000 0,29376246 0,30398889 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,29831483 0,3085265 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,29831483 0,30835347 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,30283851 0,31285391 ! ATP metabolic process GO:0046034 57 57 0,000 0,30733369 0,31731989 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,30733369 0,31714221 ! innate immune response GO:0045087 58 58 0,000 0,31180054 0,32157157 ! carboxylic acid transport GO:0046942 59 59 0,000 0,31623924 0,32596695 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,31623924 0,32578475 ! immune effector process GO:0002252 59 59 0,000 0,31623924 0,32560275 ! potassium ion transport GO:0006813 60 60 0,000 0,32064995 0,32995972 ! cellular respiration GO:0045333 62 61 0,000 0,32503285 0,33428323 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,32503285 0,33409679 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,32503285 0,33391056 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,32938812 0,33819627 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,32938812 0,33800796 ! regulation of secretion GO:0051046 65 63 0,000 0,33371592 0,34225845 ! glucose metabolic process GO:0006006 63 63 0,000 0,33371592 0,34206809 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,33371592 0,34187795 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,33371592 0,34168802 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,33801642 0,34589909 ! anion transport GO:0006820 65 65 0,000 0,34228978 0,35007773 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,34228978 0,34988357 ! regulation of hormone levels GO:0010817 66 65 0,000 0,34228978 0,34968962 ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,34653619 0,35383169 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,34653619 0,35363577 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,3507558 0,35774374 ! muscle contraction GO:0006936 67 67 0,000 0,3507558 0,35754587 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,35494877 0,36162 ! sensory perception of sound GO:0007605 71 69 0,000 0,35911528 0,36566269 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,36325548 0,36967413 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,36736955 0,37365457 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,36736955 0,37344847 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,36736955 0,3732426 ! secretion by cell GO:0032940 75 72 0,000 0,37145763 0,3771881 ! muscle system process GO:0003012 72 72 0,000 0,37145763 0,3769804 ! regulation of cytokine production GO:0001817 72 72 0,000 0,37145763 0,37677293 ! electron transport chain GO:0022900 75 74 0,000 0,37955648 0,38477591 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,37955648 0,38456438 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,38356758 0,38841486 ! response to oxidative stress GO:0006979 76 75 0,000 0,38356758 0,38820156 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,38356758 0,3879885 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,38755333 0,39180515 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,39151389 0,39559216 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,39544942 0,39934974 ! metal ion homeostasis GO:0055065 78 78 0,000 0,39544942 0,39913104 ! lipid catabolic process GO:0016042 82 81 0,000 0,40710734 0,41067259 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,41475692 0,41816029 ! ncRNA processing GO:0034470 83 83 0,000 0,41475692 0,41793166 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,41854546 0,42151874 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,42231003 0,42507776 ! hexose metabolic process GO:0019318 87 86 0,000 0,42605077 0,42860894 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,43346138 0,43582615 ! chemotaxis GO:0006935 90 89 0,000 0,43713154 0,43927668 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,43713154 0,43903729 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,44077845 0,44245898 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,44440228 0,44585378 ! visual perception GO:0007601 93 92 0,000 0,44800315 0,44922187 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,44800315 0,44897759 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,44800315 0,44873359 ! cofactor metabolic process GO:0051186 95 94 0,000 0,45513659 0,45563104 ! regulation of system process GO:0044057 98 98 0,000 0,46913425 0,46938894 ! response to other organism GO:0051707 101 100 0,000 0,47600067 0,47600067