pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6909-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 6,405E-06 0,01180384 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 1,334E-05 0,01229311 ! interaction with host GO:0051701 11 11 2,000 1,334E-05 8,195E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 2,000 1,773E-05 8,17E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 2,298E-05 8,471E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 2,916E-05 8,957E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 3,571E-05 9,403E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 3,992E-05 9,196E-03 GO:0033674|positive regulation of kinase activity, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 6,204E-05 0,01270446 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 2,000 6,458E-05 0,01190172 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,949E-04 0,0326464 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,949E-04 0,02992587 ! protein heterooligomerization GO:0051291 5 5 1,000 1,949E-04 0,02762388 ! interaction with symbiont GO:0051702 5 5 1,000 1,949E-04 0,02565074 ! mitochondrion localization GO:0051646 5 5 1,000 1,949E-04 0,02394069 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 2,001E-04 0,02304366 ! positive regulation of cell cycle GO:0045787 29 29 2,000 2,796E-04 0,03031484 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 2,796E-04 0,02863068 ! virus-host interaction GO:0019048 6 6 1,000 2,915E-04 0,02827119 ! arginine metabolic process GO:0006525 6 6 1,000 2,915E-04 0,02685763 GO:0006527|arginine catabolic process, ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,915E-04 0,0255787 GO:0070667|negative regulation of mast cell proliferation, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,915E-04 0,02441603 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,915E-04 0,02335446 ! nitric oxide mediated signal transduction GO:0007263 6 6 1,000 2,915E-04 0,02238136 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,915E-04 0,0214861 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,915E-04 0,02065972 ! localization within membrane GO:0051668 6 6 1,000 2,915E-04 0,01989454 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 4,069E-04 0,02678221 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 4,069E-04 0,02585869 GO:0000725|recombinational repair, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 4,069E-04 0,02499673 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 4,069E-04 0,02419038 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! induction of an organ GO:0001759 7 7 1,000 4,069E-04 0,02343443 ! cAMP biosynthetic process GO:0006171 7 7 1,000 4,069E-04 0,0227243 ! cell killing GO:0001906 7 7 1,000 4,069E-04 0,02205594 ! negative regulation of T cell activation GO:0050868 7 7 1,000 4,069E-04 0,02142577 ! positive regulation of cell migration GO:0030335 36 36 2,000 5,349E-04 0,02738158 ! negative regulation of proteolysis GO:0045861 8 8 1,000 5,41E-04 0,02694762 ! sex determination GO:0007530 8 8 1,000 5,41E-04 0,02623848 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 1,000 5,41E-04 0,02556569 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 5,41E-04 0,02492655 ! developmental induction GO:0031128 8 8 1,000 5,41E-04 0,02431859 GO:0045168|cell-cell signaling involved in cell fate specification, ! heart development GO:0007507 90 87 3,000 5,784E-04 0,02538032 ! meiosis GO:0007126 37 37 2,000 5,803E-04 0,02487088 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 5,803E-04 0,02430563 ! exocytosis GO:0006887 40 38 2,000 6,281E-04 0,025724 ! negative regulation of kinase activity GO:0033673 38 38 2,000 6,281E-04 0,02516478 ! meiotic cell cycle GO:0051321 38 38 2,000 6,281E-04 0,02462936 ! positive regulation of cell motion GO:0051272 39 39 2,000 6,784E-04 0,02604642 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 1,000 6,936E-04 0,02608855 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 6,936E-04 0,02556678 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 6,936E-04 0,02506547 ! negative regulation of transferase activity GO:0051348 40 40 2,000 7,311E-04 0,02591316 ! organelle localization GO:0051640 41 40 2,000 7,311E-04 0,02542423 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 8,646E-04 0,02950814 ! inositol metabolic process GO:0006020 10 10 1,000 8,646E-04 0,02897163 ! cAMP metabolic process GO:0046058 10 10 1,000 8,646E-04 0,02845428 ! epidermis morphogenesis GO:0048730 10 10 1,000 8,646E-04 0,02795508 ! neuromuscular junction development GO:0007528 10 10 1,000 8,646E-04 0,0274731 ! skin development GO:0043588 11 11 1,000 1,054E-03 0,0329165 ! activation of MAPKK activity GO:0000186 12 11 1,000 1,054E-03 0,0323679 ! cellular response to starvation GO:0009267 11 11 1,000 1,054E-03 0,03183727 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,054E-03 0,03132377 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,054E-03 0,03082657 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,054E-03 0,0303449 ! regulation of catabolic process GO:0009894 48 47 2,000 1,175E-03 0,03330483 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 1,261E-03 0,0352114 ! C21-steroid hormone metabolic process GO:0008207 13 12 1,000 1,261E-03 0,03468585 ! regulation of chromosome organization GO:0033044 12 12 1,000 1,261E-03 0,03417577 ! neurotransmitter secretion GO:0007269 14 12 1,000 1,261E-03 0,03368047 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,261E-03 0,03319932 ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,486E-03 0,03857448 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 1,486E-03 0,03803872 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,486E-03 0,03751764 ! protein tetramerization GO:0051262 13 13 1,000 1,486E-03 0,03701065 ! regulation of vasoconstriction GO:0019229 14 14 1,000 1,729E-03 0,04248393 ! collagen fibril organization GO:0030199 14 14 1,000 1,729E-03 0,04192494 ! extracellular structure organization GO:0043062 56 56 2,000 1,954E-03 0,04676338 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,989E-03 0,04700244 ! response to starvation GO:0042594 15 15 1,000 1,989E-03 0,04640748 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 1,000 1,989E-03 0,04582738 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,989E-03 0,04526161 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 2,267E-03 0,05095356 ! positive regulation of mitosis GO:0045840 16 16 1,000 2,267E-03 0,05033966 GO:0051785|positive regulation of nuclear division, ! cell fate specification GO:0001708 16 16 1,000 2,267E-03 0,04974038 ! cellular response to nutrient levels GO:0031669 16 16 1,000 2,267E-03 0,0491552 ! polyol metabolic process GO:0019751 16 16 1,000 2,267E-03 0,04858363 ! glutamine family amino acid catabolic process GO:0009065 17 16 1,000 2,267E-03 0,0480252 ! positive regulation of catabolic process GO:0009896 16 16 1,000 2,267E-03 0,04747946 ! carboxylic acid catabolic process GO:0046395 63 61 2,000 2,498E-03 0,0517355 GO:0016054|organic acid catabolic process, ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,562E-03 0,05246689 ! myelination GO:0042552 17 17 1,000 2,562E-03 0,05189033 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 2,562E-03 0,0513263 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,874E-03 0,05696124 ! meiosis I GO:0007127 18 18 1,000 2,874E-03 0,05635527 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,874E-03 0,05576205 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,874E-03 0,0551812 ! ensheathment of neurons GO:0007272 18 18 1,000 2,874E-03 0,05461232 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 2,874E-03 0,05405505 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 3,203E-03 0,05963678 ! peripheral nervous system development GO:0007422 19 19 1,000 3,203E-03 0,05904041 ! hormone biosynthetic process GO:0042446 19 19 1,000 3,203E-03 0,05845586 ! cyclic nucleotide metabolic process GO:0009187 20 20 1,000 3,549E-03 0,06413415 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 3,549E-03 0,06351149 ! lipid oxidation GO:0034440 20 20 1,000 3,549E-03 0,0629008 GO:0019395|fatty acid oxidation, ! regulation of cell migration GO:0030334 71 71 2,000 3,849E-03 0,06755519 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 3,912E-03 0,06801933 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 3,912E-03 0,06738363 ! mammary gland development GO:0030879 23 21 1,000 3,912E-03 0,06675971 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 3,912E-03 0,06614723 ! regulation of action potential in neuron GO:0019228 21 21 1,000 3,912E-03 0,0655459 ! regulation of proteolysis GO:0030162 21 21 1,000 3,912E-03 0,06495539 ! secretion by cell GO:0032940 75 72 2,000 4,004E-03 0,06588611 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 4,291E-03 0,06998995 ! sister chromatid segregation GO:0000819 22 22 1,000 4,291E-03 0,06937601 ! odontogenesis GO:0042476 22 22 1,000 4,291E-03 0,06877274 ! spindle organization GO:0007051 22 22 1,000 4,291E-03 0,06817987 ! fatty acid catabolic process GO:0009062 23 22 1,000 4,291E-03 0,06759713 ! cytokinesis GO:0000910 23 22 1,000 4,291E-03 0,06702428 ! positive regulation of growth GO:0045927 23 23 1,000 4,687E-03 0,07258707 ! calcium-mediated signaling GO:0019722 23 23 1,000 4,687E-03 0,07198218 ! Rho protein signal transduction GO:0007266 24 23 1,000 4,687E-03 0,07138729 ! regulation of action potential GO:0001508 24 24 1,000 5,099E-03 0,07702272 ! glucose homeostasis GO:0042593 24 24 1,000 5,099E-03 0,07639652 GO:0033500|carbohydrate homeostasis, ! regulation of locomotion GO:0040012 79 79 2,000 5,197E-03 0,07724685 ! regulation of cell motion GO:0051270 79 79 2,000 5,197E-03 0,07662888 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 5,526E-03 0,08083594 ! regulation of T cell proliferation GO:0042129 25 25 1,000 5,526E-03 0,08019944 ! positive regulation of DNA binding GO:0043388 26 25 1,000 5,526E-03 0,07957288 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 5,526E-03 0,07895604 ! heart morphogenesis GO:0003007 25 25 1,000 5,526E-03 0,07834868 ! negative regulation of immune system process GO:0002683 25 25 1,000 5,526E-03 0,0777506 ! MAPKKK cascade GO:0000165 82 81 2,000 5,574E-03 0,07781826 ! positive regulation of binding GO:0051099 27 26 1,000 5,97E-03 0,08273133 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 5,97E-03 0,08211393 ! regulation of T cell differentiation GO:0045580 26 26 1,000 5,97E-03 0,08150568 ! double-strand break repair GO:0006302 27 26 1,000 5,97E-03 0,08090637 ! response to insulin stimulus GO:0032868 28 26 1,000 5,97E-03 0,08031582 ! maintenance of location in cell GO:0051651 27 26 1,000 5,97E-03 0,07973382 ! synapse organization GO:0050808 26 26 1,000 5,97E-03 0,07916019 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 6,43E-03 0,08464517 ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 6,43E-03 0,08404484 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 6,905E-03 0,08962138 ! viral reproductive process GO:0022415 29 29 1,000 7,396E-03 0,0953199 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 7,396E-03 0,09465796 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! response to UV GO:0009411 29 29 1,000 7,396E-03 0,09400515 ! activation of phospholipase C activity GO:0007202 30 30 1,000 7,902E-03 0,09975065 GO:0010863|positive regulation of phospholipase C activity, ! establishment of organelle localization GO:0051656 31 30 1,000 7,902E-03 0,09907207 ! epidermis development GO:0008544 94 94 2,000 8,418E-03 0,10482514 ! skeletal muscle fiber development GO:0048741 31 31 1,000 8,424E-03 0,10419144 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 8,424E-03 0,10349683 ! regulation of DNA replication GO:0006275 32 31 1,000 8,424E-03 0,10281142 ! extracellular matrix organization GO:0030198 31 31 1,000 8,424E-03 0,10213503 ! muscle fiber development GO:0048747 32 32 1,000 8,96E-03 0,10792994 ! lipid modification GO:0030258 32 32 1,000 8,96E-03 0,1072291 ! regulation of phospholipase activity GO:0010517 32 32 1,000 8,96E-03 0,1065373 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 8,96E-03 0,10585437 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 8,96E-03 0,10518014 ! positive regulation of lipase activity GO:0060193 32 32 1,000 8,96E-03 0,10451444 ! maintenance of location GO:0051235 33 32 1,000 8,96E-03 0,10385712 ! blood circulation GO:0008015 99 98 2,000 9,436E-03 0,10869594 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 2,000 9,436E-03 0,10802081 ! activation of protein kinase activity GO:0032147 35 33 1,000 9,511E-03 0,10820748 ! regulation of neuron differentiation GO:0045664 34 33 1,000 9,511E-03 0,10754363 ! regulation of synaptic transmission GO:0050804 33 33 1,000 9,511E-03 0,10688787 ! ectoderm development GO:0007398 99 99 2,000 9,702E-03 0,10836714 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01007773 0,11188712 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01007773 0,11121714 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,01007773 0,11055513 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,01007773 0,10990096 ! viral reproduction GO:0016032 34 34 1,000 0,01007773 0,10925448 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,0106587 0,1148771 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,0106587 0,11420921 ! regulation of mitosis GO:0007088 37 36 1,000 0,01125422 0,11989323 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01125422 0,11920418 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,01125422 0,11852302 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01125422 0,11784959 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,01125422 0,11718377 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01125422 0,11652544 ! lung development GO:0030324 38 37 1,000 0,01186416 0,12215445 ! cellular amino acid catabolic process GO:0009063 38 37 1,000 0,01186416 0,12147582 ! neurotransmitter transport GO:0006836 40 38 1,000 0,01248839 0,12716075 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,01248839 0,12646206 ! chromosome segregation GO:0007059 38 38 1,000 0,01248839 0,12577101 ! axon guidance GO:0007411 39 38 1,000 0,01248839 0,12508747 ! regulation of neurological system process GO:0031644 38 38 1,000 0,01248839 0,12441132 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01312677 0,13006789 ! respiratory tube development GO:0030323 40 39 1,000 0,01312677 0,12937234 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,01312677 0,12868419 ! respiratory system development GO:0060541 40 39 1,000 0,01312677 0,12800332 ! protein oligomerization GO:0051259 39 39 1,000 0,01312677 0,12732962 ! amine catabolic process GO:0009310 42 41 1,000 0,01444546 0,13938734 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,01652639 0,15863613 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01724696 0,16469504 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01724696 0,16384609 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,01724696 0,16300586 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01798077 0,16907432 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01798077 0,16821607 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,01872771 0,17431908 ! regulation of blood pressure GO:0008217 48 47 1,000 0,01872771 0,1734431 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,01948765 0,17957873 ! DNA recombination GO:0006310 48 48 1,000 0,01948765 0,1786853 ! ossification GO:0001503 50 49 1,000 0,02026047 0,18485169 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,02026047 0,18394109 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,02026047 0,18303942 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,02026047 0,18214654 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,02104603 0,18829047 ! chromatin assembly GO:0031497 50 50 1,000 0,02104603 0,18738086 GO:0006334|nucleosome assembly, ! nitrogen compound catabolic process GO:0044270 51 50 1,000 0,02104603 0,18647999 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,02104603 0,18558774 ! rRNA metabolic process GO:0016072 51 51 1,000 0,02184423 0,19170908 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 1,000 0,02184423 0,19080051 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,02184423 0,18990051 GO:0051325|interphase, ! rRNA transcription GO:0009303 5 5 0,000 0,02233339 0,19324152 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02233339 0,19233853 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02233339 0,19144393 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02233339 0,19055761 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02233339 0,18967947 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02233339 0,18880938 ! reproductive cellular process GO:0048610 5 5 0,000 0,02233339 0,18794723 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02233339 0,18709293 ! prostate gland development GO:0030850 5 5 0,000 0,02233339 0,18624635 ! metencephalon development GO:0022037 5 5 0,000 0,02233339 0,18540741 ! water transport GO:0006833 5 5 0,000 0,02233339 0,18457598 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02233339 0,18375198 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02233339 0,18293531 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02233339 0,18212586 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02233339 0,18132354 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02233339 0,18052826 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02233339 0,17973993 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02233339 0,17895845 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02233339 0,17818374 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02233339 0,17741571 ! filopodium assembly GO:0046847 7 5 0,000 0,02233339 0,17665427 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02233339 0,17589934 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02233339 0,17515083 ! GTP metabolic process GO:0046039 5 5 0,000 0,02233339 0,17440866 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02233339 0,17367276 ! mRNA stabilization GO:0048255 5 5 0,000 0,02233339 0,17294304 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02233339 0,17221943 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02233339 0,17150185 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02233339 0,17079023 ! social behavior GO:0035176 5 5 0,000 0,02233339 0,17008448 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02233339 0,16938454 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02233339 0,16869035 ! memory GO:0007613 5 5 0,000 0,02233339 0,16800181 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02233339 0,16731888 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02233339 0,16664148 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02233339 0,16596953 ! response to lipid GO:0033993 5 5 0,000 0,02233339 0,16530299 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02233339 0,16464178 ! hippocampus development GO:0021766 6 5 0,000 0,02233339 0,16398583 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02233339 0,1633351 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02233339 0,1626895 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02233339 0,16204899 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02233339 0,16141351 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02233339 0,16078299 ! heart looping GO:0001947 5 5 0,000 0,02233339 0,16015737 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02233339 0,15953661 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02233339 0,15892063 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02233339 0,1583094 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02233339 0,15770285 ! pH reduction GO:0045851 5 5 0,000 0,02233339 0,15710093 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02233339 0,15650359 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02233339 0,15591077 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02233339 0,15532243 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02233339 0,15473851 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02233339 0,15415897 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02233339 0,15358375 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02233339 0,1530128 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02233339 0,15244609 ! adrenal gland development GO:0030325 5 5 0,000 0,02233339 0,15188356 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02233339 0,15132516 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02233339 0,15077086 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02233339 0,1502206 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02233339 0,14967434 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02233339 0,14913204 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02233339 0,14859366 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02233339 0,14805915 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02233339 0,14752847 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02233339 0,14700159 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02233339 0,14647845 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02233339 0,14595902 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02233339 0,14544327 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02233339 0,14493114 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02233339 0,14442261 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02233339 0,14391764 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02233339 0,14341618 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02233339 0,14291821 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02233339 0,14242368 ! response to ATP GO:0033198 5 5 0,000 0,02233339 0,14193257 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02233339 0,14144483 ! regulation of appetite GO:0032098 5 5 0,000 0,02233339 0,14096043 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02233339 0,14047933 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02233339 0,14000151 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02233339 0,13952693 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02233339 0,13905556 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02233339 0,13858735 ! receptor clustering GO:0043113 5 5 0,000 0,02233339 0,1381223 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02233339 0,13766035 ! fear response GO:0042596 5 5 0,000 0,02233339 0,13720148 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02233339 0,13674566 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02233339 0,13629286 ! retinol metabolic process GO:0042572 5 5 0,000 0,02233339 0,13584305 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02233339 0,1353962 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02233339 0,13495228 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02233339 0,13451126 ! parturition GO:0007567 5 5 0,000 0,02233339 0,13407311 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02233339 0,13363781 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02233339 0,13320532 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02233339 0,13277563 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02233339 0,1323487 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02233339 0,1319245 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02233339 0,13150302 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02233339 0,13108422 ! response to UV-B GO:0010224 5 5 0,000 0,02233339 0,13066808 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02233339 0,13025457 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02233339 0,12984367 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02233339 0,12943536 ! cellular extravasation GO:0045123 5 5 0,000 0,02233339 0,12902961 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02233339 0,12862639 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02233339 0,12822568 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02233339 0,12782747 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02233339 0,12743172 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02233339 0,12703841 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02233339 0,12664752 ! response to amine stimulus GO:0014075 5 5 0,000 0,02233339 0,12625903 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02233339 0,12587292 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02233339 0,12548916 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02233339 0,12510773 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02233339 0,12472862 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02233339 0,1243518 ! neuron recognition GO:0008038 5 5 0,000 0,02233339 0,12397724 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02233339 0,12360494 ! decidualization GO:0046697 5 5 0,000 0,02233339 0,12323486 ! hair follicle maturation GO:0048820 5 5 0,000 0,02233339 0,122867 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02233339 0,12250132 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02233339 0,12213782 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02233339 0,12177646 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02233339 0,12141724 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02233339 0,12106013 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02233339 0,12070512 ! postreplication repair GO:0006301 5 5 0,000 0,02233339 0,12035218 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02233339 0,1200013 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02233339 0,11965245 ! histone methylation GO:0016571 5 5 0,000 0,02233339 0,11930564 ! DNA methylation GO:0006306 5 5 0,000 0,02233339 0,11896082 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02233339 0,118618 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02233339 0,11827714 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02233339 0,11793824 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02233339 0,11760127 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02233339 0,11726622 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02233339 0,11693308 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02233339 0,11660183 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02233339 0,11627244 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02233339 0,11594491 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02233339 0,11561923 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02233339 0,11529536 ! sterol catabolic process GO:0016127 5 5 0,000 0,02233339 0,11497331 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02233339 0,11465305 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02233339 0,11433457 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02233339 0,11401785 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02233339 0,11370289 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02233339 0,11338965 ! zymogen activation GO:0031638 5 5 0,000 0,02233339 0,11307814 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02233339 0,11276834 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02233339 0,11246023 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02233339 0,1121538 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,02233339 0,11184903 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02233339 0,11154592 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02233339 0,11124444 ! nucleosome positioning GO:0016584 5 5 0,000 0,02233339 0,11094459 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02233339 0,11064636 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02233339 0,11034972 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02233339 0,11005466 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02233339 0,10976119 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02233339 0,10946927 ! NADPH regeneration GO:0006740 5 5 0,000 0,02233339 0,1091789 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02233339 0,10889006 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02233339 0,10860276 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02233339 0,10831696 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02233339 0,10803266 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02233339 0,10774985 ! sarcomere organization GO:0045214 5 5 0,000 0,02233339 0,10746852 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02233339 0,10718866 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02233339 0,10691025 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02233339 0,10663328 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02233339 0,10635774 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02233339 0,10608362 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02233339 0,10581091 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02233339 0,1055396 ! spleen development GO:0048536 5 5 0,000 0,02233339 0,10526968 ! male genitalia development GO:0030539 5 5 0,000 0,02233339 0,10500113 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02233339 0,10473396 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02233339 0,10446813 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02233339 0,10420366 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02233339 0,10394052 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02233339 0,1036787 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02233339 0,1034182 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02233339 0,10315901 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02233339 0,10290111 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02233339 0,1026445 ! ATP catabolic process GO:0006200 5 5 0,000 0,02233339 0,10238917 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02233339 0,1021351 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02233339 0,10188229 ! blastocyst formation GO:0001825 5 5 0,000 0,02233339 0,10163073 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02233339 0,1013804 ! embryonic gut development GO:0048566 5 5 0,000 0,02233339 0,10113131 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02233339 0,10088344 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02233339 0,10063678 ! activation of innate immune response GO:0002218 5 5 0,000 0,02233339 0,10039133 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02233339 0,10014707 ! catecholamine transport GO:0051937 5 5 0,000 0,02233339 0,09990399 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02233339 0,09966209 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02233339 0,09942136 ! muscle adaptation GO:0043500 5 5 0,000 0,02233339 0,09918179 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02233339 0,09894338 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02233339 0,0987061 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02233339 0,09846996 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02233339 0,09823495 ! defense response to fungus GO:0050832 5 5 0,000 0,02233339 0,09800106 ! lysogeny GO:0030069 5 5 0,000 0,02233339 0,09776828 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02233339 0,0975366 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02233339 0,09730602 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02233339 0,09707652 ! response to nicotine GO:0035094 5 5 0,000 0,02233339 0,0968481 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02233339 0,09662076 ! nucleus localization GO:0051647 5 5 0,000 0,02233339 0,09639448 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02233339 0,09616926 ! cell fate commitment GO:0045165 52 52 1,000 0,02265493 0,0973264 ! response to light stimulus GO:0009416 53 52 1,000 0,02265493 0,09710006 ! regulation of T cell activation GO:0050863 53 53 1,000 0,02347801 0,10039437 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,02431336 0,10372575 ! hormone metabolic process GO:0042445 55 54 1,000 0,02431336 0,1034862 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,02431336 0,10324775 ! nucleosome organization GO:0034728 55 55 1,000 0,02516086 0,10660105 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,02516086 0,10635655 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,02516086 0,10611317 ! reproductive developmental process GO:0003006 56 56 1,000 0,02602038 0,10948757 ! regulation of nervous system development GO:0051960 57 56 1,000 0,02602038 0,10923817 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02674178 0,1120116 ! axon extension GO:0048675 7 6 0,000 0,02674178 0,1117576 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02674178 0,11150476 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,02674178 0,11125305 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,02674178 0,11100248 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02674178 0,11075304 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02674178 0,11050471 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02674178 0,1102575 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02674178 0,11001139 ! regulation of S phase GO:0033261 6 6 0,000 0,02674178 0,10976638 ! myotube differentiation GO:0014902 6 6 0,000 0,02674178 0,10952245 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02674178 0,10927961 ! bone remodeling GO:0046849 6 6 0,000 0,02674178 0,10903784 ! N-glycan processing GO:0006491 6 6 0,000 0,02674178 0,10879714 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02674178 0,1085575 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02674178 0,10831891 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02674178 0,10808137 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02674178 0,10784486 ! RNA methylation GO:0001510 6 6 0,000 0,02674178 0,10760939 ! cartilage condensation GO:0001502 7 6 0,000 0,02674178 0,10737495 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02674178 0,10714153 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02674178 0,10690912 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02674178 0,10667771 ! artery development GO:0060840 6 6 0,000 0,02674178 0,10644731 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02674178 0,10621789 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02674178 0,10598947 ! androgen metabolic process GO:0008209 6 6 0,000 0,02674178 0,10576202 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02674178 0,10553555 ! limbic system development GO:0021761 7 6 0,000 0,02674178 0,10531005 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02674178 0,10508551 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02674178 0,10486192 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02674178 0,10463928 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02674178 0,10441759 ! pathogenesis GO:0009405 6 6 0,000 0,02674178 0,10419683 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02674178 0,10397701 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02674178 0,10375811 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02674178 0,10354013 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02674178 0,10332307 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02674178 0,10310691 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02674178 0,10289166 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02674178 0,1026773 ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02674178 0,10246383 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02674178 0,10225125 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02674178 0,10203955 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02674178 0,10182872 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02674178 0,10161877 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02674178 0,10140968 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02674178 0,10120144 ! ER overload response GO:0006983 6 6 0,000 0,02674178 0,10099406 ! V(D)J recombination GO:0033151 6 6 0,000 0,02674178 0,10078753 ! focal adhesion formation GO:0048041 7 6 0,000 0,02674178 0,10058184 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02674178 0,10037699 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02674178 0,10017297 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02674178 0,09996978 ! regulation of heart rate GO:0002027 6 6 0,000 0,02674178 0,09976741 ! lipid digestion GO:0044241 6 6 0,000 0,02674178 0,09956586 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02674178 0,09936513 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02674178 0,0991652 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02674178 0,09896607 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02674178 0,09876774 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02674178 0,09857021 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02674178 0,09837346 ! ruffle organization GO:0031529 6 6 0,000 0,02674178 0,0981775 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02674178 0,09798231 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02674178 0,0977879 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02674178 0,09759426 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02674178 0,09740139 ! L-amino acid transport GO:0015807 6 6 0,000 0,02674178 0,09720928 ! bone mineralization GO:0030282 6 6 0,000 0,02674178 0,09701792 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02674178 0,09682731 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02674178 0,09663746 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02674178 0,09644834 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02674178 0,09625997 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02674178 0,09607233 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02674178 0,09588541 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,02674178 0,09569923 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02674178 0,09551377 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02674178 0,09532902 ! regulation of organ growth GO:0046620 6 6 0,000 0,02674178 0,09514499 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02674178 0,09496166 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02674178 0,09477904 ! response to dsRNA GO:0043331 6 6 0,000 0,02674178 0,09459713 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02674178 0,09441591 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02674178 0,09423538 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02674178 0,09405554 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02674178 0,09387639 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02674178 0,09369791 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02674178 0,09352012 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02674178 0,093343 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02674178 0,09316655 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02674178 0,09299076 ! erythrocyte development GO:0048821 6 6 0,000 0,02674178 0,09281564 ! renal water homeostasis GO:0003091 6 6 0,000 0,02674178 0,09264117 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02674178 0,09246736 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02674178 0,0922942 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02674178 0,09212169 ! ribosome assembly GO:0042255 6 6 0,000 0,02674178 0,09194982 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02674178 0,09177859 ! diencephalon development GO:0021536 6 6 0,000 0,02674178 0,091608 ! fucose catabolic process GO:0019317 6 6 0,000 0,02674178 0,09143804 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02674178 0,09126871 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02674178 0,09110001 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02674178 0,09093192 ! regulation of cell division GO:0051302 6 6 0,000 0,02674178 0,09076446 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02674178 0,09059762 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02674178 0,09043138 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02674178 0,09026576 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02674178 0,09010074 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02674178 0,08993632 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02674178 0,0897725 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02674178 0,08960928 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02674178 0,08944665 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02674178 0,08928461 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02674178 0,08912315 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02674178 0,08896228 ! thymus development GO:0048538 6 6 0,000 0,02674178 0,08880199 ! lymph node development GO:0048535 6 6 0,000 0,02674178 0,08864227 ! organic cation transport GO:0015695 6 6 0,000 0,02674178 0,08848313 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02674178 0,08832456 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02674178 0,08816655 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02674178 0,08800911 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02674178 0,08785223 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02674178 0,08769591 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02674178 0,08754015 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02674178 0,08738493 ! alditol metabolic process GO:0019400 6 6 0,000 0,02674178 0,08723027 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02674178 0,08707615 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02674178 0,08692258 ! maternal placenta development GO:0001893 6 6 0,000 0,02674178 0,08676955 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02674178 0,08661705 ! regulation of binding GO:0051098 60 57 1,000 0,02689181 0,08695018 ! dephosphorylation GO:0016311 60 59 1,000 0,02866993 0,09253708 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,02866993 0,09237531 ! regulation of cell development GO:0060284 60 59 1,000 0,02866993 0,09221409 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,02957638 0,09496389 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,03049428 0,0977408 ! respiratory burst GO:0045730 7 7 0,000 0,03113093 0,09960816 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03113093 0,09943553 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03113093 0,0992635 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03113093 0,09909206 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03113093 0,09892121 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03113093 0,09875095 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03113093 0,09858128 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03113093 0,09841218 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03113093 0,09824367 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03113093 0,09807573 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03113093 0,09790837 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03113093 0,09774157 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03113093 0,09757535 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03113093 0,09740968 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03113093 0,09724458 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03113093 0,09708004 ! axis specification GO:0009798 7 7 0,000 0,03113093 0,09691605 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03113093 0,09675262 ! visual behavior GO:0007632 7 7 0,000 0,03113093 0,09658974 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03113093 0,0964274 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03113093 0,09626561 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03113093 0,09610436 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03113093 0,09594365 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03113093 0,09578348 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03113093 0,09562384 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03113093 0,09546473 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03113093 0,09530615 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03113093 0,0951481 ! digestive system development GO:0055123 7 7 0,000 0,03113093 0,09499057 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03113093 0,09483356 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03113093 0,09467707 ! protein targeting to ER GO:0045047 8 7 0,000 0,03113093 0,09452109 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03113093 0,09436563 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03113093 0,09421068 ! endoderm development GO:0007492 7 7 0,000 0,03113093 0,09405623 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03113093 0,0939023 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03113093 0,09374886 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,03113093 0,09359593 ! response to hexose stimulus GO:0009746 7 7 0,000 0,03113093 0,09344349 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03113093 0,09329155 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03113093 0,0931401 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03113093 0,09298915 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03113093 0,09283868 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03113093 0,0926887 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03113093 0,0925392 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03113093 0,09239018 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03113093 0,09224164 ! response to X-ray GO:0010165 7 7 0,000 0,03113093 0,09209358 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,03113093 0,091946 ! UV protection GO:0009650 7 7 0,000 0,03113093 0,09179888 ! DNA integration GO:0015074 7 7 0,000 0,03113093 0,09165224 ! myofibril assembly GO:0030239 7 7 0,000 0,03113093 0,09150607 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03113093 0,09136035 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03113093 0,09121511 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03113093 0,09107032 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03113093 0,090926 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03113093 0,09078212 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03113093 0,09063871 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03113093 0,09049575 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03113093 0,09035323 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03113093 0,09021117 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03113093 0,09006955 ! axon cargo transport GO:0008088 7 7 0,000 0,03113093 0,08992837 ! eating behavior GO:0042755 7 7 0,000 0,03113093 0,08978764 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03113093 0,08964735 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03113093 0,08950749 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03113093 0,08936807 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03113093 0,08922909 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03113093 0,08909053 ! cranial nerve development GO:0021545 7 7 0,000 0,03113093 0,08895241 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03113093 0,08881471 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03113093 0,08867744 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03113093 0,08854059 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03113093 0,08840416 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03113093 0,08826816 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03113093 0,08813257 ! platelet activation GO:0030168 8 7 0,000 0,03113093 0,0879974 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03113093 0,08786264 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03113093 0,08772829 ! natural killer cell activation GO:0030101 7 7 0,000 0,03113093 0,08759436 ! response to gamma radiation GO:0010332 8 7 0,000 0,03113093 0,08746083 ! NADP metabolic process GO:0006739 7 7 0,000 0,03113093 0,08732771 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03113093 0,08719499 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03113093 0,08706268 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03113093 0,08693076 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03113093 0,08679925 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03113093 0,08666813 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03113093 0,08653741 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03113093 0,08640708 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03113093 0,08627715 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03113093 0,0861476 ! cell-cell recognition GO:0009988 8 7 0,000 0,03113093 0,08601845 ! hormone catabolic process GO:0042447 7 7 0,000 0,03113093 0,08588968 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03113093 0,08576129 ! oxygen transport GO:0015671 7 7 0,000 0,03113093 0,08563329 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03113093 0,08550567 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03113093 0,08537843 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03113093 0,08525156 ! regulation of axon extension GO:0030516 7 7 0,000 0,03113093 0,08512508 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03113093 0,08499897 ! adult feeding behavior GO:0008343 7 7 0,000 0,03113093 0,08487323 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03113093 0,08474786 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03113093 0,08462287 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03113093 0,08449824 ! response to cold GO:0009409 7 7 0,000 0,03113093 0,08437397 ! axonogenesis GO:0007409 66 62 1,000 0,03142351 0,08504189 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,03142351 0,0849172 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,03236396 0,08733056 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,03427804 0,09236028 ! regulation of hormone levels GO:0010817 66 65 1,000 0,03427804 0,09222545 ! DNA packaging GO:0006323 66 66 1,000 0,03525146 0,09470619 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,03525146 0,09456833 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03550092 0,09509912 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03550092 0,0949611 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03550092 0,09482347 ! positive regulation of translation GO:0045727 8 8 0,000 0,03550092 0,09468624 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03550092 0,09454941 ! superoxide anion generation GO:0042554 8 8 0,000 0,03550092 0,09441298 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03550092 0,09427694 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03550092 0,09414129 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03550092 0,09400603 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03550092 0,09387115 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03550092 0,09373667 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03550092 0,09360257 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03550092 0,09346885 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03550092 0,09333551 ! zinc ion transport GO:0006829 8 8 0,000 0,03550092 0,09320256 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03550092 0,09306998 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03550092 0,09293778 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03550092 0,09280595 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03550092 0,0926745 ! lipid localization GO:0010876 8 8 0,000 0,03550092 0,09254342 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03550092 0,0924127 ! response to cAMP GO:0051591 8 8 0,000 0,03550092 0,09228236 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03550092 0,09215239 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03550092 0,09202278 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03550092 0,09189353 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03550092 0,09176465 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03550092 0,09163613 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03550092 0,09150796 ! sensory perception of taste GO:0050909 8 8 0,000 0,03550092 0,09138016 ! organelle fusion GO:0048284 8 8 0,000 0,03550092 0,09125271 ! pancreas development GO:0031016 8 8 0,000 0,03550092 0,09112562 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03550092 0,09099888 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03550092 0,09087249 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03550092 0,09074646 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03550092 0,09062077 ! sperm motility GO:0030317 8 8 0,000 0,03550092 0,09049543 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03550092 0,09037043 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03550092 0,09024579 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03550092 0,09012148 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03550092 0,08999752 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03550092 0,08987389 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03550092 0,08975061 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03550092 0,08962766 ! Golgi organization GO:0007030 8 8 0,000 0,03550092 0,08950505 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03550092 0,08938278 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03550092 0,08926084 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03550092 0,08913923 ! fructose metabolic process GO:0006000 8 8 0,000 0,03550092 0,08901795 ! mannose metabolic process GO:0006013 9 8 0,000 0,03550092 0,088897 ! NAD metabolic process GO:0019674 8 8 0,000 0,03550092 0,08877638 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03550092 0,08865609 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03550092 0,08853612 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,03550092 0,08841648 ! response to fungus GO:0009620 8 8 0,000 0,03550092 0,08829716 ! stem cell differentiation GO:0048863 8 8 0,000 0,03550092 0,08817816 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03550092 0,08805948 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03550092 0,08794112 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03550092 0,08782308 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03550092 0,08770535 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03550092 0,08758794 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03550092 0,08747085 ! vasoconstriction GO:0042310 8 8 0,000 0,03550092 0,08735406 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03550092 0,08723759 ! muscle cell development GO:0055001 8 8 0,000 0,03550092 0,08712143 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03550092 0,08700558 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03550092 0,08689003 ! sensory perception of pain GO:0019233 8 8 0,000 0,03550092 0,08677479 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03550092 0,08665986 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03550092 0,08654523 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03550092 0,0864309 ! chromatin silencing GO:0006342 8 8 0,000 0,03550092 0,08631688 ! tissue regeneration GO:0042246 8 8 0,000 0,03550092 0,08620315 ! salivary gland development GO:0007431 8 8 0,000 0,03550092 0,08608973 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03550092 0,0859766 ! T cell homeostasis GO:0043029 8 8 0,000 0,03550092 0,08586377 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03550092 0,08575124 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03550092 0,085639 ! water homeostasis GO:0030104 8 8 0,000 0,03550092 0,08552705 ! cofactor transport GO:0051181 8 8 0,000 0,03550092 0,0854154 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03550092 0,08530403 ! acid secretion GO:0046717 8 8 0,000 0,03550092 0,08519296 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03550092 0,08508218 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03550092 0,08497168 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03550092 0,08486147 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03550092 0,08475155 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03550092 0,08464191 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03550092 0,08453255 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03550092 0,08442348 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03550092 0,08431468 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,03550092 0,08420617 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03550092 0,08409794 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03550092 0,08398998 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03550092 0,0838823 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03550092 0,0837749 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03550092 0,08366777 ! peptide hormone secretion GO:0030072 8 8 0,000 0,03550092 0,08356091 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03550092 0,08345433 ! actin filament polymerization GO:0030041 9 8 0,000 0,03550092 0,08334802 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03550092 0,08324198 ! peptide hormone processing GO:0016486 8 8 0,000 0,03550092 0,08313621 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03550092 0,0830307 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03550092 0,08292547 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,03623565 0,08453456 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,03623565 0,08442769 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,03623565 0,08432109 ! response to radiation GO:0009314 70 68 1,000 0,0372305 0,08652687 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,0372305 0,08641789 ! response to nutrient levels GO:0031667 69 69 1,000 0,0382359 0,08863994 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,0382359 0,08852859 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,0382359 0,08841751 ! cell part morphogenesis GO:0032990 75 70 1,000 0,03925173 0,09065281 ! wound healing GO:0042060 74 70 1,000 0,03925173 0,09053936 ! muscle tissue development GO:0060537 72 70 1,000 0,03925173 0,09042618 ! lactation GO:0007595 10 9 0,000 0,03985183 0,09169404 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03985183 0,09157971 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03985183 0,09146566 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03985183 0,0913519 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03985183 0,09123842 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03985183 0,09112522 ! viral genome replication GO:0019079 9 9 0,000 0,03985183 0,0910123 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03985183 0,09089966 ! copper ion transport GO:0006825 9 9 0,000 0,03985183 0,0907873 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03985183 0,09067522 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03985183 0,09056341 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03985183 0,09045188 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03985183 0,09034062 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03985183 0,09022964 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03985183 0,09011893 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03985183 0,09000849 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03985183 0,08989832 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03985183 0,08978842 ! phospholipid efflux GO:0033700 9 9 0,000 0,03985183 0,08967879 ! response to alkaloid GO:0043279 10 9 0,000 0,03985183 0,08956942 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03985183 0,08946032 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03985183 0,08935149 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03985183 0,08924292 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03985183 0,08913462 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03985183 0,08902658 ! response to ethanol GO:0045471 9 9 0,000 0,03985183 0,0889188 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03985183 0,08881128 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03985183 0,08870402 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03985183 0,08859702 ! methionine metabolic process GO:0006555 9 9 0,000 0,03985183 0,08849027 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03985183 0,08838379 ! cerebral cortex development GO:0021987 9 9 0,000 0,03985183 0,08827756 ! response to osmotic stress GO:0006970 9 9 0,000 0,03985183 0,08817158 ! pigmentation during development GO:0048066 9 9 0,000 0,03985183 0,08806586 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03985183 0,08796039 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03985183 0,08785518 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03985183 0,08775021 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03985183 0,0876455 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03985183 0,08754103 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03985183 0,08743682 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03985183 0,08733285 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03985183 0,08722913 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03985183 0,08712565 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03985183 0,08702242 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03985183 0,08691944 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03985183 0,0868167 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03985183 0,0867142 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03985183 0,08661194 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03985183 0,08650993 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03985183 0,08640815 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03985183 0,08630661 ! DNA replication initiation GO:0006270 9 9 0,000 0,03985183 0,08620531 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03985183 0,08610425 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03985183 0,08600343 ! regulation of cellular pH GO:0030641 9 9 0,000 0,03985183 0,08590284 ! histone acetylation GO:0016573 9 9 0,000 0,03985183 0,08580248 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03985183 0,08570236 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03985183 0,08560248 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03985183 0,08550282 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03985183 0,0854034 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03985183 0,08530421 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03985183 0,08520525 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03985183 0,08510652 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03985183 0,08500802 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03985183 0,08490974 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03985183 0,08481169 ! collagen catabolic process GO:0030574 9 9 0,000 0,03985183 0,08471387 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03985183 0,08461627 ! purine base metabolic process GO:0006144 9 9 0,000 0,03985183 0,0845189 ! gas transport GO:0015669 9 9 0,000 0,03985183 0,08442175 ! cholesterol efflux GO:0033344 9 9 0,000 0,03985183 0,08432483 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03985183 0,08422813 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03985183 0,08413165 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03985183 0,08403538 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03985183 0,08393934 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03985183 0,08384352 ! defense response to virus GO:0051607 9 9 0,000 0,03985183 0,08374792 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03985183 0,08365254 ! actin filament-based movement GO:0030048 9 9 0,000 0,03985183 0,08355737 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03985183 0,08346242 ! ribosome biogenesis GO:0042254 71 71 1,000 0,04027791 0,084259 ! regulation of cell activation GO:0050865 71 71 1,000 0,04027791 0,08416347 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,04131431 0,08623133 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,04131431 0,08613379 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04418375 0,09201203 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,04418375 0,09190818 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,04418375 0,09180456 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04418375 0,09170118 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04418375 0,09159803 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04418375 0,09149511 ! neuron maturation GO:0042551 10 10 0,000 0,04418375 0,09139242 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04418375 0,09128996 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04418375 0,09118773 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,04418375 0,09108574 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,04418375 0,09098396 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04418375 0,09088242 ! hormone secretion GO:0046879 10 10 0,000 0,04418375 0,0907811 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04418375 0,09068001 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04418375 0,09057914 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,04418375 0,0904785 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04418375 0,09037808 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04418375 0,09027788 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04418375 0,0901779 ! glial cell development GO:0021782 10 10 0,000 0,04418375 0,09007815 ! phototransduction GO:0007602 11 10 0,000 0,04418375 0,08997862 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,04418375 0,0898793 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,04418375 0,08978021 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,04418375 0,08968133 ! fat cell differentiation GO:0045444 10 10 0,000 0,04418375 0,08958267 ! myoblast differentiation GO:0045445 10 10 0,000 0,04418375 0,08948423 ! centrosome cycle GO:0007098 10 10 0,000 0,04418375 0,089386 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04418375 0,08928799 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04418375 0,08919019 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04418375 0,08909261 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,04418375 0,08899524 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04418375 0,08889809 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04418375 0,08880114 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04418375 0,08870441 ! plasma membrane organization GO:0007009 10 10 0,000 0,04418375 0,08860789 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,04418375 0,08851157 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,04418375 0,08841547 ! lysosomal transport GO:0007041 10 10 0,000 0,04418375 0,08831957 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,04418375 0,08822389 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,04418375 0,08812841 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,04418375 0,08803313 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,04418375 0,08793806 ! exocrine system development GO:0035272 10 10 0,000 0,04418375 0,0878432 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,04418375 0,08774854 ! embryo implantation GO:0007566 11 10 0,000 0,04418375 0,08765409 ! regulation of protein binding GO:0043393 11 10 0,000 0,04418375 0,08755984 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04418375 0,08746579 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04418375 0,08737194 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04418375 0,08727829 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04418375 0,08718485 ! protein export from nucleus GO:0006611 10 10 0,000 0,04418375 0,0870916 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04418375 0,08699855 ! cytolysis GO:0019835 10 10 0,000 0,04418375 0,08690571 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04418375 0,08681306 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04418375 0,0867206 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,04418375 0,08662835 ! histone deacetylation GO:0016575 10 10 0,000 0,04418375 0,08653629 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04418375 0,08644442 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,04418375 0,08635275 ! gland morphogenesis GO:0022612 10 10 0,000 0,04418375 0,08626128 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04418375 0,08617 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04418375 0,08607891 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04418375 0,08598801 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04418375 0,08589731 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,04418375 0,08580679 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04418375 0,08571647 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04418375 0,08562634 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,04418375 0,08553639 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04418375 0,08544664 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04418375 0,08535707 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04418375 0,08526769 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,04418375 0,0851785 ! nerve development GO:0021675 10 10 0,000 0,04418375 0,0850895 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,04418375 0,08500068 ! gut development GO:0048565 10 10 0,000 0,04418375 0,08491204 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,04418375 0,08482359 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,04418375 0,08473532 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,04418375 0,08464724 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04418375 0,08455934 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04418375 0,08447163 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,04418375 0,08438409 ! protein stabilization GO:0050821 10 10 0,000 0,04418375 0,08429674 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,046646 0,08890236 ! regulation of protein modification process GO:0031399 79 78 1,000 0,04774155 0,09089636 ! protein secretion GO:0009306 11 11 0,000 0,04849675 0,09223891 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04849675 0,09214382 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04849675 0,09204892 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04849675 0,09195422 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04849675 0,09185972 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04849675 0,09176541 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04849675 0,09167129 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04849675 0,09157736 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04849675 0,09148363 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04849675 0,09139009 ! signal complex assembly GO:0007172 11 11 0,000 0,04849675 0,09129674 ! microtubule-based transport GO:0010970 11 11 0,000 0,04849675 0,09120358 ! endothelial cell migration GO:0043542 11 11 0,000 0,04849675 0,09111061 ! peroxisomal transport GO:0043574 11 11 0,000 0,04849675 0,09101783 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04849675 0,09092523 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,04849675 0,09083283 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,04849675 0,09074061 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,04849675 0,09064858 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04849675 0,09055674 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04849675 0,09046509 ! T cell proliferation GO:0042098 11 11 0,000 0,04849675 0,09037361 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04849675 0,09028233 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04849675 0,09019123 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04849675 0,09010031 ! spinal cord development GO:0021510 11 11 0,000 0,04849675 0,09000957 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04849675 0,08991902 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04849675 0,08982865 ! digestive system process GO:0022600 11 11 0,000 0,04849675 0,08973846 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04849675 0,08964845 ! fucose metabolic process GO:0006004 11 11 0,000 0,04849675 0,08955862 ! membrane budding GO:0006900 11 11 0,000 0,04849675 0,08946897 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04849675 0,0893795 ! monoamine transport GO:0015844 11 11 0,000 0,04849675 0,08929021 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04849675 0,0892011 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04849675 0,08911217 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,04849675 0,08902341 ! body fluid secretion GO:0007589 11 11 0,000 0,04849675 0,08893483 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,04849675 0,08884643 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04849675 0,0887582 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04849675 0,08867014 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04849675 0,08858226 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04849675 0,08849456 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04849675 0,08840703 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04849675 0,08831967 ! oogenesis GO:0048477 11 11 0,000 0,04849675 0,08823248 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04849675 0,08814547 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04849675 0,08805863 ! vitamin transport GO:0051180 11 11 0,000 0,04849675 0,08797195 ! muscle maintenance GO:0046716 12 11 0,000 0,04849675 0,08788545 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04849675 0,08779912 ! hindbrain development GO:0030902 11 11 0,000 0,04849675 0,08771296 ! steroid catabolic process GO:0006706 11 11 0,000 0,04849675 0,08762697 ! endocrine process GO:0050886 11 11 0,000 0,04849675 0,08754114 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04849675 0,08745548 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04849675 0,08736999 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04849675 0,08728467 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04849675 0,08719952 ! neuron projection development GO:0031175 85 80 1,000 0,04996104 0,08974483 ! tube development GO:0035295 83 81 1,000 0,05108477 0,09167404 ! lipid catabolic process GO:0016042 82 81 1,000 0,05108477 0,09158486 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,05279091 0,09455165 ! translational initiation GO:0006413 12 12 0,000 0,05279091 0,09445985 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,05279091 0,09436823 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,05279091 0,09427679 ! initiation of viral infection GO:0019059 12 12 0,000 0,05279091 0,09418552 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,05279091 0,09409443 ! iron ion transport GO:0006826 13 12 0,000 0,05279091 0,09400352 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,05279091 0,09391279 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,05279091 0,09382222 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,05279091 0,09373184 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,05279091 0,09364162 ! collagen metabolic process GO:0032963 12 12 0,000 0,05279091 0,09355158 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,05279091 0,09346172 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,05279091 0,09337202 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,05279091 0,0932825 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,05279091 0,09319315 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,05279091 0,09310397 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,05279091 0,09301496 ! actomyosin structure organization GO:0031032 12 12 0,000 0,05279091 0,09292612 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,05279091 0,09283745 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,05279091 0,09274895 ! retinoid metabolic process GO:0001523 12 12 0,000 0,05279091 0,09266061 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,05279091 0,09257245 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,05279091 0,09248445 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,05279091 0,09239662 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,05279091 0,09230896 ! acute-phase response GO:0006953 12 12 0,000 0,05279091 0,09222147 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,05279091 0,09213413 ! vacuolar transport GO:0007034 12 12 0,000 0,05279091 0,09204697 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,05279091 0,09195997 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,05279091 0,09187313 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,05279091 0,09178646 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,05279091 0,09169995 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,05279091 0,0916136 ! male gonad development GO:0008584 12 12 0,000 0,05279091 0,09152742 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,05279091 0,0914414 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,05279091 0,09135554 ! renal system process GO:0003014 12 12 0,000 0,05279091 0,09126984 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,05279091 0,0911843 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,05279091 0,09109892 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,05279091 0,0910137 ! pallium development GO:0021543 13 12 0,000 0,05279091 0,09092864 ! cell fate determination GO:0001709 12 12 0,000 0,05279091 0,09084374 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,05279091 0,090759 ! somitogenesis GO:0001756 13 12 0,000 0,05279091 0,09067441 ! G1 phase GO:0051318 13 12 0,000 0,05279091 0,09058999 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,05279091 0,09050572 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,05279091 0,0904216 ! detection of light stimulus GO:0009583 13 12 0,000 0,05279091 0,09033765 ! synaptogenesis GO:0007416 12 12 0,000 0,05279091 0,09025385 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,05279091 0,0901702 ! hormone transport GO:0009914 12 12 0,000 0,05279091 0,09008671 ! heme biosynthetic process GO:0006783 12 12 0,000 0,05279091 0,09000337 ! spermatid differentiation GO:0048515 13 12 0,000 0,05279091 0,08992019 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,05279091 0,08983716 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,05279091 0,08975429 ! neural tube closure GO:0001843 13 12 0,000 0,05279091 0,08967156 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,05279091 0,08958899 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,05279091 0,08950657 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,05279091 0,08942431 ! ncRNA processing GO:0034470 83 83 1,000 0,05335972 0,09030484 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,05683937 0,09610546 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,05706631 0,09640075 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,05706631 0,09631247 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,05706631 0,09622435 ! phenol metabolic process GO:0018958 13 13 0,000 0,05706631 0,0961364 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,05706631 0,0960486 ! gluconeogenesis GO:0006094 13 13 0,000 0,05706631 0,09596096 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,05706631 0,09587349 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,05706631 0,09578617 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,05706631 0,09569901 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,05706631 0,09561202 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,05706631 0,09552517 ! regeneration GO:0031099 13 13 0,000 0,05706631 0,09543849 ! keratinization GO:0031424 13 13 0,000 0,05706631 0,09535196 ! post-embryonic development GO:0009791 14 13 0,000 0,05706631 0,0952656 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,05706631 0,09517938 ! patterning of blood vessels GO:0001569 13 13 0,000 0,05706631 0,09509332 ! vasculogenesis GO:0001570 13 13 0,000 0,05706631 0,09500742 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,05706631 0,09492168 ! regulation of innate immune response GO:0045088 13 13 0,000 0,05706631 0,09483608 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,05706631 0,09475065 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,05706631 0,09466536 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,05706631 0,09458023 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,05706631 0,09449525 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,05706631 0,09441043 ! autophagy GO:0006914 13 13 0,000 0,05706631 0,09432576 ! receptor metabolic process GO:0043112 14 13 0,000 0,05706631 0,09424123 ! actin filament bundle formation GO:0051017 13 13 0,000 0,05706631 0,09415686 ! ureteric bud development GO:0001657 13 13 0,000 0,05706631 0,09407265 ! cell aging GO:0007569 13 13 0,000 0,05706631 0,09398858 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,05706631 0,09390466 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,05706631 0,09382089 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,05706631 0,09373727 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,05706631 0,0936538 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,05706631 0,09357048 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,05706631 0,0934873 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,05706631 0,09340428 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,05706631 0,0933214 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,05706631 0,09323867 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,05706631 0,09315608 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,05706631 0,09307364 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,05706631 0,09299135 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,05706631 0,0929092 ! vasodilation GO:0042311 14 13 0,000 0,05706631 0,0928272 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,05706631 0,09274534 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,05706631 0,09266363 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,05706631 0,09258206 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,05706631 0,09250063 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,05706631 0,09241935 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,05706631 0,09233821 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,05706631 0,09225721 ! immunoglobulin production GO:0002377 13 13 0,000 0,05706631 0,09217635 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,05706631 0,09209564 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,05706631 0,09201506 ! cell-cell junction organization GO:0045216 13 13 0,000 0,05706631 0,09193463 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,05706631 0,09185434 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,05706631 0,09177419 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,05706631 0,09169417 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,05706631 0,0916143 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,05706631 0,09153457 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,05706631 0,09145497 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,05706631 0,09137551 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,05706631 0,0912962 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,05706631 0,09121701 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,05706631 0,09113797 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,05706631 0,09105906 ! blastocyst development GO:0001824 13 13 0,000 0,05706631 0,09098029 ! telomere organization GO:0032200 13 13 0,000 0,05706631 0,09090166 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,05706631 0,09082316 ! regulation of amine transport GO:0051952 13 13 0,000 0,05706631 0,09074479 ! tissue homeostasis GO:0001894 13 13 0,000 0,05706631 0,09066657 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,05706631 0,09058847 ! male gamete generation GO:0048232 90 88 1,000 0,05920281 0,09389911 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,05920281 0,09381838 ! neuron fate commitment GO:0048663 14 14 0,000 0,06132304 0,09709482 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,06132304 0,09701147 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,06132304 0,09692827 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,06132304 0,09684521 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,06132304 0,0967623 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,06132304 0,09667953 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,06132304 0,09659689 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,06132304 0,0965144 ! protein amino acid acylation GO:0043543 14 14 0,000 0,06132304 0,09643205 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,06132304 0,09634984 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,06132304 0,09626777 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,06132304 0,09618584 ! vesicle docking GO:0048278 14 14 0,000 0,06132304 0,09610405 ! superoxide metabolic process GO:0006801 15 14 0,000 0,06132304 0,0960224 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,06132304 0,09594089 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,06132304 0,09585951 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,06132304 0,09577828 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,06132304 0,09569718 ! hair cycle GO:0042633 14 14 0,000 0,06132304 0,09561621 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,06132304 0,09553539 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,06132304 0,0954547 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,06132304 0,09537415 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,06132304 0,09529373 ! lysosome organization GO:0007040 14 14 0,000 0,06132304 0,09521345 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,06132304 0,0951333 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,06132304 0,09505329 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,06132304 0,09497342 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,06132304 0,09489367 ! primary neural tube formation GO:0014020 15 14 0,000 0,06132304 0,09481406 ! peptide cross-linking GO:0018149 14 14 0,000 0,06132304 0,09473459 ! regulation of behavior GO:0050795 14 14 0,000 0,06132304 0,09465525 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,06132304 0,09457604 ! base-excision repair GO:0006284 14 14 0,000 0,06132304 0,09449696 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,06132304 0,09441802 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,06132304 0,0943392 ! formation of primary germ layer GO:0001704 14 14 0,000 0,06132304 0,09426052 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,06132304 0,09418197 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,06132304 0,09410355 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,06132304 0,09402526 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,06132304 0,0939471 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,06132304 0,09386907 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,06132304 0,09379117 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,06132304 0,0937134 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,06132304 0,09363576 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,06132304 0,09355825 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,06132304 0,09348086 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,06281155 0,09567082 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,06403105 0,09744775 ! tissue morphogenesis GO:0048729 94 93 1,000 0,06525868 0,09923411 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,06556117 0,0996119 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,06556117 0,09952985 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,06556117 0,09944793 ! positive regulation of ossification GO:0045778 15 15 0,000 0,06556117 0,09936615 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,06556117 0,0992845 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,06556117 0,09920298 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,06556117 0,0991216 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,06556117 0,09904036 ! response to vitamin GO:0033273 15 15 0,000 0,06556117 0,09895924 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,06556117 0,09887826 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,06556117 0,09879741 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,06556117 0,09871669 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,06556117 0,09863611 ! ovarian follicle development GO:0001541 15 15 0,000 0,06556117 0,09855566 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,06556117 0,09847533 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,06556117 0,09839514 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,06556117 0,09831508 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,06556117 0,09823515 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,06556117 0,09815535 ! heme metabolic process GO:0042168 15 15 0,000 0,06556117 0,09807568 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,06556117 0,09799614 ! chromosome condensation GO:0030261 15 15 0,000 0,06556117 0,09791672 ! response to ionizing radiation GO:0010212 16 15 0,000 0,06556117 0,09783744 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,06556117 0,09775828 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,06556117 0,09767925 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,06556117 0,09760035 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,06556117 0,09752158 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,06556117 0,09744293 ! phospholipid transport GO:0015914 15 15 0,000 0,06556117 0,09736441 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,06556117 0,09728602 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,06556117 0,09720775 ! glutathione metabolic process GO:0006749 16 15 0,000 0,06556117 0,09712961 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,06556117 0,09705159 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,06556117 0,0969737 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,06556117 0,09689594 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,06556117 0,0968183 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,06556117 0,09674078 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,06556117 0,09666339 ! protein homooligomerization GO:0051260 15 15 0,000 0,06556117 0,09658612 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,06556117 0,09650897 ! blood vessel development GO:0001568 95 94 1,000 0,06649435 0,09780453 ! vasculature development GO:0001944 97 96 1,000 0,06898944 0,10139357 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06978078 0,10247488 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06978078 0,10239329 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06978078 0,10231183 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06978078 0,1022305 ! learning GO:0007612 16 16 0,000 0,06978078 0,1021493 ! circadian rhythm GO:0007623 16 16 0,000 0,06978078 0,10206823 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06978078 0,10198729 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,06978078 0,10190647 ! vacuole organization GO:0007033 16 16 0,000 0,06978078 0,10182579 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06978078 0,10174523 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06978078 0,1016648 ! vesicle targeting GO:0006903 17 16 0,000 0,06978078 0,1015845 ! segmentation GO:0035282 17 16 0,000 0,06978078 0,10150432 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06978078 0,10142427 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06978078 0,10134434 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06978078 0,10126454 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06978078 0,10118487 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06978078 0,10110532 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06978078 0,1010259 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06978078 0,1009466 ! pentose metabolic process GO:0019321 16 16 0,000 0,06978078 0,10086743 ! fatty acid transport GO:0015908 16 16 0,000 0,06978078 0,10078838 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06978078 0,10070945 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06978078 0,10063065 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06978078 0,10055197 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06978078 0,10047341 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06978078 0,10039498 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06978078 0,10031667 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06978078 0,10023848 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06978078 0,10016041 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06978078 0,10008247 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06978078 0,10000464 ! regulation of coagulation GO:0050818 17 16 0,000 0,06978078 0,09992694 ! anti-apoptosis GO:0006916 100 99 1,000 0,07279012 0,10415543 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,07398194 0,10577868 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,07398194 0,10569668 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,07398194 0,10561481 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,07398194 0,10553306 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,07398194 0,10545144 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,07398194 0,10536995 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,07398194 0,10528859 ! leukocyte adhesion GO:0007159 17 17 0,000 0,07398194 0,10520734 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,07398194 0,10512623 ! sensory perception of smell GO:0007608 17 17 0,000 0,07398194 0,10504524 ! glucose transport GO:0015758 17 17 0,000 0,07398194 0,10496437 ! cell junction assembly GO:0034329 18 17 0,000 0,07398194 0,10488363 ! tissue remodeling GO:0048771 17 17 0,000 0,07398194 0,10480301 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,07398194 0,10472252 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,07398194 0,10464215 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,07398194 0,1045619 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,07398194 0,10448178 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,07398194 0,10440177 ! neural crest cell development GO:0014032 19 17 0,000 0,07398194 0,1043219 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,07398194 0,10424214 ! negative regulation of cell development GO:0010721 18 17 0,000 0,07398194 0,1041625 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,07398194 0,10408299 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,07398194 0,1040036 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,07398194 0,10392433 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,07398194 0,10384518 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,07398194 0,10376615 ! pigmentation GO:0043473 17 17 0,000 0,07398194 0,10368724 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,07398194 0,10360845 ! adult locomotory behavior GO:0008344 17 17 0,000 0,07398194 0,10352978 ! embryonic organ development GO:0048568 17 17 0,000 0,07398194 0,10345123 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,07398194 0,1033728 ! liver development GO:0001889 17 17 0,000 0,07398194 0,10329448 ! gene silencing GO:0016458 17 17 0,000 0,07398194 0,10321629 ! response to hormone stimulus GO:0009725 102 100 1,000 0,07407213 0,10326394 ! muscle organ development GO:0007517 102 100 1,000 0,07407213 0,10318589 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,07816474 0,10880485 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,07816474 0,10872273 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,07816474 0,10864074 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,07816474 0,10855887 ! membrane docking GO:0022406 18 18 0,000 0,07816474 0,10847712 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,07816474 0,1083955 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,07816474 0,108314 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,07816474 0,10823262 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,07816474 0,10815137 ! hexose transport GO:0008645 18 18 0,000 0,07816474 0,10807023 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,07816474 0,10798922 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,07816474 0,10790833 ! striated muscle contraction GO:0006941 18 18 0,000 0,07816474 0,10782756 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,07816474 0,10774691 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,07816474 0,10766638 ! ceramide metabolic process GO:0006672 18 18 0,000 0,07816474 0,10758597 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,07816474 0,10750569 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,07816474 0,10742552 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,07816474 0,10734547 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,07816474 0,10726554 ! B cell differentiation GO:0030183 18 18 0,000 0,07816474 0,10718573 ! BMP signaling pathway GO:0030509 18 18 0,000 0,07816474 0,10710604 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,07816474 0,10702646 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,07816474 0,10694701 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,08232926 0,11256144 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,08232926 0,112478 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,08232926 0,11239468 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,08232926 0,11231149 ! glial cell differentiation GO:0010001 19 19 0,000 0,08232926 0,11222842 ! regulation of pH GO:0006885 19 19 0,000 0,08232926 0,11214547 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,08232926 0,11206264 ! feeding behavior GO:0007631 19 19 0,000 0,08232926 0,11197994 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,08232926 0,11189736 ! peroxisome organization GO:0007031 19 19 0,000 0,08232926 0,1118149 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,08232926 0,11173256 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,08232926 0,11165034 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,08232926 0,11156825 ! metanephros development GO:0001656 19 19 0,000 0,08232926 0,11148627 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,08232926 0,11140442 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,08232926 0,11132268 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,08232926 0,11124107 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,08232926 0,11115957 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,08232926 0,1110782 ! regulation of protein stability GO:0031647 19 19 0,000 0,08232926 0,11099694 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,08232926 0,1109158 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,08232926 0,11083478 ! eye morphogenesis GO:0048592 19 19 0,000 0,08232926 0,11075388 ! regulation of cell shape GO:0008360 21 19 0,000 0,08232926 0,1106731 ! placenta development GO:0001890 19 19 0,000 0,08232926 0,11059243 ! response to heat GO:0009408 19 19 0,000 0,08232926 0,11051188 ! vesicle localization GO:0051648 20 19 0,000 0,08232926 0,11043145 ! regulation of muscle development GO:0048634 21 20 0,000 0,08647556 0,1159087 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,08647556 0,11582446 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,08647556 0,11574035 ! negative regulation of binding GO:0051100 21 20 0,000 0,08647556 0,11565635 ! organic ether metabolic process GO:0018904 20 20 0,000 0,08647556 0,11557248 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,08647556 0,11548874 ! neural tube development GO:0021915 21 20 0,000 0,08647556 0,11540511 ! nucleus organization GO:0006997 20 20 0,000 0,08647556 0,1153216 ! phagocytosis GO:0006909 21 20 0,000 0,08647556 0,11523822 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,08647556 0,11515495 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,08647556 0,11507181 ! protein targeting to membrane GO:0006612 22 20 0,000 0,08647556 0,11498879 ! chromatin remodeling GO:0006338 20 20 0,000 0,08647556 0,11490588 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,08647556 0,1148231 ! female gamete generation GO:0007292 20 20 0,000 0,08647556 0,11474043 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,08647556 0,11465788 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,08647556 0,11457545 ! RNA modification GO:0009451 20 20 0,000 0,08647556 0,11449314 ! single fertilization GO:0007338 21 20 0,000 0,08647556 0,11441095 ! regulation of B cell activation GO:0050864 20 20 0,000 0,08647556 0,11432888 ! mRNA catabolic process GO:0006402 21 21 0,000 0,09060373 0,11970084 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,09060373 0,1196151 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,09060373 0,11952948 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,09060373 0,11944397 ! Notch signaling pathway GO:0007219 22 21 0,000 0,09060373 0,1193586 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,09060373 0,11927334 ! ear morphogenesis GO:0042471 21 21 0,000 0,09060373 0,11918821 ! organic anion transport GO:0015711 21 21 0,000 0,09060373 0,11910319 ! cholesterol transport GO:0030301 21 21 0,000 0,09060373 0,1190183 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,09060373 0,11893353 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,09060373 0,11884888 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,09060373 0,11876435 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,09060373 0,11867994 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,09060373 0,11859565 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,09060373 0,11851148 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,09060373 0,11842743 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,09060373 0,1183435 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,09060373 0,11825969 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,09060373 0,11817599 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,09471385 0,12344952 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,09471385 0,12336228 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,09471385 0,12327516 ! regulation of ion transport GO:0043269 22 22 0,000 0,09471385 0,12318816 ! cell junction organization GO:0034330 23 22 0,000 0,09471385 0,12310128 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,09471385 0,12301453 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,09471385 0,1229279 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,09471385 0,12284139 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,09471385 0,12275501 ! ovulation cycle process GO:0022602 22 22 0,000 0,09471385 0,12266874 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,09471385 0,1225826 ! cell chemotaxis GO:0060326 23 22 0,000 0,09471385 0,12249658 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,09471385 0,12241067 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,09471385 0,12232489 ! male sex differentiation GO:0046661 22 22 0,000 0,09471385 0,12223923 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,09471385 0,12215369 ! biopolymer methylation GO:0043414 22 22 0,000 0,09471385 0,12206827 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,09471385 0,12198296 ! detection of external stimulus GO:0009581 23 22 0,000 0,09471385 0,12189778 ! neuron migration GO:0001764 22 22 0,000 0,09471385 0,12181271 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,09471385 0,12172777 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,09471385 0,12164294 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,09471385 0,12155823 ! aerobic respiration GO:0009060 22 22 0,000 0,09471385 0,12147364 ! cytokine production GO:0001816 22 22 0,000 0,09471385 0,12138917 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,09471385 0,12130481 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,09880598 0,12645794 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,09880598 0,12637018 ! viral infectious cycle GO:0019058 23 23 0,000 0,09880598 0,12628254 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,09880598 0,12619503 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,09880598 0,12610764 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,09880598 0,12602036 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,09880598 0,12593321 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,09880598 0,12584618 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,09880598 0,12575927 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,09880598 0,12567248 ! endocrine system development GO:0035270 23 23 0,000 0,09880598 0,12558581 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,09880598 0,12549926 ! female gonad development GO:0008585 23 23 0,000 0,09880598 0,12541283 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,09880598 0,12532652 ! lipid homeostasis GO:0055088 23 23 0,000 0,09880598 0,12524032 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,09880598 0,12515425 ! cell projection assembly GO:0030031 25 23 0,000 0,09880598 0,12506829 ! mitochondrial transport GO:0006839 24 24 0,000 0,10288022 0,13013606 ! gliogenesis GO:0042063 24 24 0,000 0,10288022 0,1300468 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,10288022 0,12995767 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,10288022 0,12986866 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,10288022 0,12977977 ! T cell differentiation GO:0030217 24 24 0,000 0,10288022 0,129691 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,10288022 0,12960235 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,10288022 0,12951382 ! ovulation cycle GO:0042698 24 24 0,000 0,10288022 0,12942542 ! fertilization GO:0009566 25 24 0,000 0,10288022 0,12933713 ! maintenance of protein location GO:0045185 25 24 0,000 0,10288022 0,12924897 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,10288022 0,12916093 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,10288022 0,129073 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,10288022 0,1289852 ! glucan metabolic process GO:0044042 25 24 0,000 0,10288022 0,12889751 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,10693662 0,13388872 ! negative regulation of secretion GO:0051048 26 25 0,000 0,10693662 0,13379782 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,10693662 0,13370705 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,10693662 0,1336164 ! cellular component disassembly GO:0022411 26 25 0,000 0,10693662 0,13352588 ! endosome transport GO:0016197 25 25 0,000 0,10693662 0,13343547 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,10693662 0,13334519 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,10693662 0,13325503 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,10693662 0,133165 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,10693662 0,13307508 ! excretion GO:0007588 25 25 0,000 0,10693662 0,13298529 ! gastrulation GO:0007369 25 25 0,000 0,10693662 0,13289561 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,10693662 0,13280606 ! regulation of endocytosis GO:0030100 25 25 0,000 0,10693662 0,13271663 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,10693662 0,13262732 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,10693662 0,13253813 ! positive regulation of defense response GO:0031349 26 26 0,000 0,11097527 0,13745123 ! glycolysis GO:0006096 26 26 0,000 0,11097527 0,13735892 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,11097527 0,13726673 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,11097527 0,13717467 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,11097527 0,13708273 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,11097527 0,13699091 ! cellular defense response GO:0006968 26 26 0,000 0,11097527 0,13689922 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,11097527 0,13680765 ! regulation of protein secretion GO:0050708 26 26 0,000 0,11097527 0,1367162 ! germ cell development GO:0007281 27 26 0,000 0,11097527 0,13662487 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,11097527 0,13653366 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,11097527 0,13644258 ! chloride transport GO:0006821 27 27 0,000 0,11499625 0,14129206 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,11499625 0,14119793 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,11499625 0,14110392 ! learning or memory GO:0007611 28 27 0,000 0,11499625 0,14101004 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,11499625 0,14091628 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,11499625 0,14082265 ! peptide metabolic process GO:0006518 29 27 0,000 0,11499625 0,14072914 ! activation of caspase activity GO:0006919 27 27 0,000 0,11499625 0,14063576 ! mesenchymal cell development GO:0014031 29 27 0,000 0,11499625 0,1405425 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,11499625 0,14044936 ! defense response to bacterium GO:0042742 27 27 0,000 0,11499625 0,14035635 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,11499625 0,14026346 ! cell growth GO:0016049 27 27 0,000 0,11499625 0,14017069 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,11899962 0,1449546 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,11899962 0,14485885 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,11899962 0,14476324 ! carbohydrate transport GO:0008643 28 28 0,000 0,11899962 0,14466775 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,11899962 0,14457238 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,11899962 0,14447714 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,11899962 0,14438203 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,11899962 0,14428704 ! histone modification GO:0016570 28 28 0,000 0,11899962 0,14419218 ! developmental growth GO:0048589 28 28 0,000 0,11899962 0,14409744 ! cartilage development GO:0051216 29 28 0,000 0,11899962 0,14400283 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,12298547 0,14872849 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,12298547 0,14863096 ! leukocyte migration GO:0050900 30 29 0,000 0,12298547 0,14853356 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,12298547 0,14843629 ! antigen processing and presentation GO:0019882 29 29 0,000 0,12298547 0,14833915 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,12298547 0,14824213 ! tRNA processing GO:0008033 29 29 0,000 0,12298547 0,14814524 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,12298547 0,14804848 ! covalent chromatin modification GO:0016569 29 29 0,000 0,12298547 0,14795184 ! adult behavior GO:0030534 30 29 0,000 0,12298547 0,14785533 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,12298547 0,14775894 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,12298547 0,14766268 ! transition metal ion transport GO:0000041 31 30 0,000 0,12695386 0,1523281 ! RNA catabolic process GO:0006401 30 30 0,000 0,12695386 0,15222899 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,12695386 0,15213002 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,12695386 0,15203117 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,12695386 0,15193244 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,12695386 0,15183385 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,12695386 0,15173538 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,12695386 0,15163705 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,12695386 0,15153884 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,12695386 0,15144075 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,12695386 0,1513428 ! response to temperature stimulus GO:0009266 30 30 0,000 0,12695386 0,15124497 ! regulation of ossification GO:0030278 30 30 0,000 0,12695386 0,15114726 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,12695386 0,15104969 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,12695386 0,15095223 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,12695386 0,15085491 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,12695386 0,15075771 ! vesicle organization GO:0016050 30 30 0,000 0,12695386 0,15066063 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,12695386 0,15056368 ! regulation of translational initiation GO:0006446 31 31 0,000 0,13090487 0,15514963 ! membrane fusion GO:0006944 31 31 0,000 0,13090487 0,15504992 ! B cell activation GO:0042113 31 31 0,000 0,13090487 0,15495034 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,13090487 0,15485088 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,13090487 0,15475156 ! ion transmembrane transport GO:0034220 31 31 0,000 0,13090487 0,15465236 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,13090487 0,15455328 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,13090487 0,15445434 ! digestion GO:0007586 31 31 0,000 0,13090487 0,15435552 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,13090487 0,15425683 ! regulation of heart contraction GO:0008016 31 31 0,000 0,13090487 0,15415826 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,13090487 0,15405982 ! camera-type eye development GO:0043010 31 31 0,000 0,13090487 0,1539615 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,13090487 0,15386331 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,13090487 0,15376525 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,13090487 0,15366731 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,13090487 0,1535695 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,13090487 0,15347181 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,13483858 0,15798315 ! cell redox homeostasis GO:0045454 32 32 0,000 0,13483858 0,15788278 ! glucose catabolic process GO:0006007 32 32 0,000 0,13483858 0,15778254 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,13483858 0,15768242 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,13483858 0,15758243 ! cell maturation GO:0048469 32 32 0,000 0,13483858 0,15748257 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,13483858 0,15738284 ! nuclear export GO:0051168 32 32 0,000 0,13483858 0,15728323 ! kidney development GO:0001822 32 32 0,000 0,13483858 0,15718374 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,13483858 0,15708439 ! negative regulation of cell size GO:0045792 33 33 0,000 0,13875505 0,16154489 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,13875505 0,1614429 ! amino acid transport GO:0006865 33 33 0,000 0,13875505 0,16134104 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,13875505 0,16123932 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,13875505 0,16113772 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,13875505 0,16103624 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,13875505 0,1609349 ! regulation of actin filament length GO:0030832 34 34 0,000 0,14265436 0,16535345 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,14265436 0,16524952 ! response to metal ion GO:0010038 34 34 0,000 0,14265436 0,16514572 ! ear development GO:0043583 34 34 0,000 0,14265436 0,16504205 ! muscle cell differentiation GO:0042692 35 34 0,000 0,14265436 0,16493851 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,14265436 0,1648351 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,14265436 0,16473182 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,14265436 0,16462867 ! secondary metabolic process GO:0019748 34 34 0,000 0,14265436 0,16452565 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,14265436 0,16442276 ! detection of stimulus GO:0051606 36 34 0,000 0,14265436 0,16431999 ! acute inflammatory response GO:0002526 35 35 0,000 0,14653659 0,1686864 ! regulation of cellular component size GO:0032535 35 35 0,000 0,14653659 0,16858111 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,14653659 0,16847594 ! mesoderm development GO:0007498 35 35 0,000 0,14653659 0,1683709 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,14653659 0,168266 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,14653659 0,16816123 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,14653659 0,16805658 ! inorganic anion transport GO:0015698 35 35 0,000 0,14653659 0,16795207 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,14653659 0,16784769 ! regulation of immune effector process GO:0002697 35 35 0,000 0,14653659 0,16774344 ! hydrogen transport GO:0006818 36 36 0,000 0,1504018 0,17206115 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1504018 0,17195441 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1504018 0,17184781 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1504018 0,17174133 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1504018 0,17163499 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1504018 0,17152878 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1504018 0,1714227 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,1504018 0,17131676 ! gonad development GO:0008406 36 36 0,000 0,1504018 0,17121094 ! activation of immune response GO:0002253 36 36 0,000 0,1504018 0,17110526 ! coagulation GO:0050817 39 36 0,000 0,1504018 0,1709997 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,15425007 0,17526687 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,15425007 0,17515889 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 0,000 0,15425007 0,17505103 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,15425007 0,17494331 ! eye development GO:0001654 37 37 0,000 0,15425007 0,17483571 ! negative regulation of growth GO:0045926 37 37 0,000 0,15425007 0,17472825 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,15425007 0,17462093 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,15425007 0,17451373 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,15425007 0,17440667 ! adaptive immune response GO:0002250 37 37 0,000 0,15425007 0,17429974 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,15808146 0,17851969 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,15808146 0,17841037 ! urogenital system development GO:0001655 38 38 0,000 0,15808146 0,17830118 ! hexose catabolic process GO:0019320 38 38 0,000 0,15808146 0,17819213 ! RNA elongation GO:0006354 38 38 0,000 0,15808146 0,17808321 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,15808146 0,17797443 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,15808146 0,17786577 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,16189606 0,18204664 ! hemostasis GO:0007599 42 39 0,000 0,16189606 0,18193563 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,16189606 0,18182476 ! response to unfolded protein GO:0006986 39 39 0,000 0,16189606 0,18171403 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,16189606 0,18160343 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,16189606 0,18149297 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,16189606 0,18138264 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,16189606 0,18127244 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,16189606 0,18116238 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,16189606 0,18105245 ! developmental maturation GO:0021700 39 39 0,000 0,16189606 0,18094265 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,16189606 0,18083299 ! limb development GO:0060173 39 39 0,000 0,16189606 0,18072346 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,16569393 0,18485104 ! DNA catabolic process GO:0006308 41 40 0,000 0,16569393 0,18473921 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,16569393 0,18462752 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,16569393 0,18451596 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,16947514 0,18861273 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,16947514 0,1884989 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,16947514 0,18838521 ! regulation of caspase activity GO:0043281 41 41 0,000 0,16947514 0,18827166 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,16947514 0,18815824 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,16947514 0,18804496 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,16947514 0,18793182 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,16947514 0,18781881 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,17323977 0,19187553 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,17323977 0,19176029 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,17323977 0,19164519 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,17323977 0,19153023 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,17323977 0,1914154 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,17323977 0,19130071 ! protein ubiquitination GO:0016567 43 42 0,000 0,17323977 0,19118616 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,17323977 0,19107175 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,17323977 0,19095747 ! forebrain development GO:0030900 43 42 0,000 0,17323977 0,19084333 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,17323977 0,19072932 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,17323977 0,19061546 ! reproductive structure development GO:0048608 43 43 0,000 0,17698787 0,1946233 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,17698787 0,19450725 ! mitochondrion organization GO:0007005 44 43 0,000 0,17698787 0,19439133 ! alcohol catabolic process GO:0046164 43 43 0,000 0,17698787 0,19427555 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,17698787 0,19415991 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,17698787 0,19404441 ! humoral immune response GO:0006959 44 44 0,000 0,18071954 0,1980179 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,18071954 0,19790024 ! mRNA transport GO:0051028 44 44 0,000 0,18071954 0,19778272 ! protein import into nucleus GO:0006606 44 44 0,000 0,18071954 0,19766534 ! vitamin metabolic process GO:0006766 44 44 0,000 0,18071954 0,19754811 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,18071954 0,19743101 ! amine biosynthetic process GO:0009309 46 45 0,000 0,18443482 0,20137048 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,18443482 0,20125126 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,18443482 0,20113218 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,18443482 0,20101323 ! nuclear import GO:0051170 45 45 0,000 0,18443482 0,20089443 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,18443482 0,20077577 ! protein processing GO:0016485 45 45 0,000 0,18443482 0,20065725 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,1881338 0,20456082 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,1881338 0,20444021 ! tube morphogenesis GO:0035239 47 46 0,000 0,1881338 0,20431974 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,1881338 0,20419941 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,1881338 0,20407922 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,1881338 0,20395917 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,1881338 0,20383927 ! sex differentiation GO:0007548 47 47 0,000 0,19181654 0,20770734 ! amine transport GO:0015837 47 47 0,000 0,19181654 0,20758537 ! rhythmic process GO:0048511 47 47 0,000 0,19181654 0,20746355 ! calcium ion transport GO:0006816 48 48 0,000 0,19548311 0,21130521 ! actin filament organization GO:0007015 50 48 0,000 0,19548311 0,21118135 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,19548311 0,21105763 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,19548311 0,21093406 ! protein localization in nucleus GO:0034504 48 48 0,000 0,19548311 0,21081064 ! leukocyte differentiation GO:0002521 50 49 0,000 0,19913359 0,21462175 ! cell cycle arrest GO:0007050 49 49 0,000 0,19913359 0,21449632 ! divalent metal ion transport GO:0070838 49 49 0,000 0,19913359 0,21437103 ! response to nutrient GO:0007584 49 49 0,000 0,19913359 0,21424588 ! response to bacterium GO:0009617 50 49 0,000 0,19913359 0,21412089 ! regulation of ligase activity GO:0051340 50 49 0,000 0,19913359 0,21399603 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,19913359 0,21387133 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,19913359 0,21374677 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,20276803 0,21752123 ! negative regulation of transport GO:0051051 51 50 0,000 0,20276803 0,21739469 ! RNA transport GO:0050658 50 50 0,000 0,20276803 0,2172683 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,20276803 0,21714205 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,20276803 0,21701595 ! transcription initiation GO:0006352 50 50 0,000 0,20276803 0,21689 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,20276803 0,21676419 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,20276803 0,21663853 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,2063865 0,22037678 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,2063865 0,22024917 ! positive regulation of immune response GO:0050778 51 51 0,000 0,2063865 0,22012171 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,2063865 0,2199944 ! protein maturation GO:0051604 51 51 0,000 0,2063865 0,21986724 ! RNA localization GO:0006403 52 52 0,000 0,20998908 0,2235759 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,20998908 0,22344681 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,20998908 0,22331788 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,20998908 0,22318909 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,20998908 0,22306045 ! sodium ion transport GO:0006814 53 53 0,000 0,21357583 0,22673978 ! tRNA metabolic process GO:0006399 53 53 0,000 0,21357583 0,22660925 ! response to hypoxia GO:0001666 53 53 0,000 0,21357583 0,22647886 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,21357583 0,22634863 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,21357583 0,22621854 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,21357583 0,2260886 ! regulation of protein transport GO:0051223 53 53 0,000 0,21357583 0,22595882 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 0,000 0,21714682 0,22960505 ! response to virus GO:0009615 54 54 0,000 0,21714682 0,22947339 ! sulfur metabolic process GO:0006790 55 54 0,000 0,21714682 0,22934189 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,22070212 0,23296335 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,22070212 0,23283 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,22070212 0,2326968 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,22424179 0,23629366 ! ATP metabolic process GO:0046034 57 57 0,000 0,22776589 0,23987002 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,22776589 0,23973303 ! regulation of protein localization GO:0032880 58 57 0,000 0,22776589 0,2395962 ! innate immune response GO:0045087 58 58 0,000 0,23127451 0,24314827 ! carboxylic acid transport GO:0046942 59 59 0,000 0,23476769 0,24668007 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,23476769 0,24653952 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,23476769 0,24639912 ! protein localization in organelle GO:0033365 59 59 0,000 0,23476769 0,24625888 ! immune effector process GO:0002252 59 59 0,000 0,23476769 0,2461188 ! potassium ion transport GO:0006813 60 60 0,000 0,23824551 0,24962278 ! protein polymerization GO:0051258 65 60 0,000 0,23824551 0,24948095 ! cellular respiration GO:0045333 62 61 0,000 0,24170803 0,25296303 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,24170803 0,25281946 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,24170803 0,25267606 ! lipid transport GO:0006869 62 62 0,000 0,24515531 0,25613449 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,24515531 0,25598937 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,24515531 0,25584442 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,24515531 0,25569963 ! protein import GO:0017038 62 62 0,000 0,24515531 0,255555 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,24515531 0,25541054 ! regulation of secretion GO:0051046 65 63 0,000 0,24858743 0,25883991 ! glucose metabolic process GO:0006006 63 63 0,000 0,24858743 0,25869375 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,24858743 0,25854776 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,24858743 0,25840194 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,25200445 0,2618062 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,25200445 0,2616587 ! angiogenesis GO:0001525 65 64 0,000 0,25200445 0,26151137 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,25200445 0,26136421 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,25200445 0,26121721 ! anion transport GO:0006820 65 65 0,000 0,25540642 0,26459474 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,25879342 0,26795296 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,25879342 0,26780251 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,25879342 0,26765223 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,26216551 0,27098768 ! muscle contraction GO:0006936 67 67 0,000 0,26216551 0,27083578 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,26216551 0,27068405 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,26552275 0,27399688 ! regulation of cell size GO:0008361 68 68 0,000 0,26552275 0,27384355 ! regulation of translation GO:0006417 69 69 0,000 0,2688652 0,27713566 ! sensory perception of sound GO:0007605 71 69 0,000 0,2688652 0,27698075 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,2688652 0,27682602 ! positive regulation of transport GO:0051050 71 70 0,000 0,27219293 0,2800958 ! growth GO:0040007 70 70 0,000 0,27219293 0,2799395 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,27219293 0,27978337 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,27550601 0,28303097 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,27550601 0,2828733 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,27550601 0,2827158 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,27550601 0,28255847 ! muscle system process GO:0003012 72 72 0,000 0,27880448 0,28578235 ! sensory organ development GO:0007423 72 72 0,000 0,27880448 0,28562349 ! regulation of cytokine production GO:0001817 72 72 0,000 0,27880448 0,28546481 ! electron transport chain GO:0022900 75 74 0,000 0,28535789 0,29201254 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,28535789 0,29185049 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,28861294 0,29501589 ! response to oxidative stress GO:0006979 76 75 0,000 0,28861294 0,29485236 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,28861294 0,294689 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,29185365 0,29783293 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,29185365 0,29766811 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,29508006 0,30079234 ! microtubule-based movement GO:0007018 82 78 0,000 0,29829225 0,30389863 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,29829225 0,30373073 ! metal ion homeostasis GO:0055065 78 78 0,000 0,29829225 0,30356301 ! regulation of immune response GO:0050776 78 78 0,000 0,29829225 0,30339549 ! nuclear transport GO:0051169 79 79 0,000 0,30149027 0,30647908 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,30467419 0,30954494 ! lymphocyte activation GO:0046649 82 81 0,000 0,30784405 0,31259316 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,31414189 0,3188125 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,31414189 0,31863704 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,31726998 0,32163287 ! regulation of cellular localization GO:0060341 86 85 0,000 0,32038425 0,32461142 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,32038425 0,32443307 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,32038425 0,3242549 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,32038425 0,32407694 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,32348478 0,32703371 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,32348478 0,32685441 ! chemotaxis GO:0006935 90 89 0,000 0,33270445 0,33598592 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,33270445 0,33580192 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,33575057 0,33869091 ! brain development GO:0007420 91 90 0,000 0,33575057 0,33850563 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,33878322 0,34137643 ! DNA replication GO:0006260 91 91 0,000 0,33878322 0,34118988 ! visual perception GO:0007601 93 92 0,000 0,34180248 0,34404258 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,34180248 0,34385479 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,34180248 0,34366719 ! regulation of response to stress GO:0080134 97 94 0,000 0,34780101 0,34950778 ! pattern specification process GO:0007389 96 94 0,000 0,34780101 0,34931731 ! cofactor metabolic process GO:0051186 95 94 0,000 0,34780101 0,34912705 ! regulation of cell growth GO:0001558 97 96 0,000 0,35374663 0,35490203 ! endocytosis GO:0006897 99 98 0,000 0,35963977 0,36061812 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,35963977 0,36042203 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,35963977 0,36022614 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,3654809 0,36587795 ! response to other organism GO:0051707 101 100 0,000 0,3654809 0,36567931 ! hemopoiesis GO:0030097 104 100 0,000 0,3654809 0,3654809