pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6909-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 3,000 2,496E-06 5,74E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 3,543E-06 4,074E-03 ! positive regulation of axonogenesis GO:0050772 19 14 2,000 2,263E-05 0,01734865 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 3,281E-05 0,01886854 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 4,191E-05 0,01927633 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 5,937E-05 0,02275755 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 6,964E-05 0,02288199 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 8,101E-05 0,02329071 ! interaction with host GO:0051701 37 23 2,000 1,072E-04 0,0274073 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 1,222E-04 0,02810836 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,222E-04 0,02555305 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,613E-04 0,03092526 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,613E-04 0,0285464 ! regulation of axonogenesis GO:0050770 51 29 2,000 2,174E-04 0,03572255 ! positive regulation of neurogenesis GO:0050769 45 30 2,000 2,409E-04 0,03693794 ! activation of MAPKKK activity GO:0000185 10 6 1,000 2,414E-04 0,03469945 ! male sex determination GO:0030238 9 6 1,000 2,414E-04 0,0326583 ! interaction with symbiont GO:0051702 8 6 1,000 2,414E-04 0,03084395 ! progesterone metabolic process GO:0042448 8 6 1,000 2,414E-04 0,02922059 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 2,000 2,926E-04 0,03364822 ! positive regulation of cell development GO:0010720 54 33 2,000 3,209E-04 0,03514812 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,371E-04 0,03523748 ! protein heterooligomerization GO:0051291 10 7 1,000 3,371E-04 0,03370541 ! regulation of neuron projection development GO:0010975 63 34 2,000 3,51E-04 0,03363288 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 3,51E-04 0,03228757 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 2,000 3,51E-04 0,03104574 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 3,946E-04 0,03361687 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 4,482E-04 0,03681845 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 4,482E-04 0,03554884 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 4,482E-04 0,03436388 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 4,482E-04 0,03325537 ! induction of an organ GO:0001759 11 8 1,000 4,482E-04 0,03221614 ! regulation of embryonic development GO:0045995 16 8 1,000 4,482E-04 0,03123989 ! mitochondrion localization GO:0051646 12 8 1,000 4,482E-04 0,03032107 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 5,283E-04 0,03471372 ! regulation of developmental growth GO:0048638 13 9 1,000 5,748E-04 0,03672172 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 5,748E-04 0,03572924 ! regulation of glycolysis GO:0006110 15 9 1,000 5,748E-04 0,034789 ! motor axon guidance GO:0008045 14 9 1,000 5,748E-04 0,03389697 ! localization within membrane GO:0051668 15 9 1,000 5,748E-04 0,03304955 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 7,051E-04 0,03955395 ! response to insulin stimulus GO:0032868 63 43 2,000 7,051E-04 0,03861219 ! regulation of B cell proliferation GO:0030888 15 10 1,000 7,166E-04 0,03832878 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 7,166E-04 0,03745767 GO:0043470|regulation of carbohydrate catabolic process, ! developmental induction GO:0031128 13 10 1,000 7,166E-04 0,03662528 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of cell projection organization GO:0031344 83 44 2,000 7,545E-04 0,0377245 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 7,545E-04 0,03692185 ! positive regulation of cell cycle GO:0045787 77 45 2,000 8,06E-04 0,03862266 ! response to UV GO:0009411 75 46 2,000 8,598E-04 0,04035672 ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 1,000 8,735E-04 0,04018203 ! virus-host interaction GO:0019048 17 11 1,000 8,735E-04 0,03939415 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 8,735E-04 0,03863657 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 8,735E-04 0,03790758 GO:0000725|recombinational repair, ! negative regulation of proteolysis GO:0045861 16 11 1,000 8,735E-04 0,03720559 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 8,735E-04 0,03652912 GO:0042130|negative regulation of T cell proliferation, ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 9,157E-04 0,03761044 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,045E-03 0,04218586 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,045E-03 0,04145851 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cAMP biosynthetic process GO:0006171 20 12 1,000 1,045E-03 0,04075583 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 1,163E-03 0,04456281 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,163E-03 0,04383227 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,232E-03 0,04571509 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,434E-03 0,05235001 ! inositol metabolic process GO:0006020 20 14 1,000 1,434E-03 0,05153204 ! activation of MAPKK activity GO:0000186 21 14 1,000 1,434E-03 0,05073924 ! epidermis morphogenesis GO:0048730 29 14 1,000 1,434E-03 0,04997047 ! cellular response to starvation GO:0009267 21 14 1,000 1,434E-03 0,04922464 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 1,000 1,434E-03 0,04850075 ! cell killing GO:0001906 20 14 1,000 1,434E-03 0,04779784 ! exocytosis GO:0006887 74 55 2,000 1,448E-03 0,04756465 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,525E-03 0,04940573 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 1,605E-03 0,05127735 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 1,605E-03 0,05057492 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 1,65E-03 0,05129005 ! skin development GO:0043588 25 15 1,000 1,65E-03 0,05060618 ! lipid phosphorylation GO:0046834 23 15 1,000 1,65E-03 0,04994031 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 1,65E-03 0,04929174 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of kinase activity GO:0033673 100 58 2,000 1,688E-03 0,0497703 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,881E-03 0,0547633 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,881E-03 0,05407876 ! meiosis GO:0007126 96 61 2,000 1,952E-03 0,05541762 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of transferase activity GO:0051348 105 61 2,000 1,952E-03 0,0547418 ! meiotic cell cycle GO:0051321 97 62 2,000 2,045E-03 0,05666786 ! organelle localization GO:0051640 96 62 2,000 2,045E-03 0,05599324 ! neuromuscular junction development GO:0007528 23 17 1,000 2,126E-03 0,05753282 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 2,126E-03 0,05686383 ! positive regulation of DNA replication GO:0045740 29 18 1,000 2,386E-03 0,06307081 ! protein amino acid ADP-ribosylation GO:0006471 27 18 1,000 2,386E-03 0,0623541 ! cAMP metabolic process GO:0046058 33 18 1,000 2,386E-03 0,06165349 ! cellular response to nutrient levels GO:0031669 27 18 1,000 2,386E-03 0,06096845 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 2,386E-03 0,06029847 ! negative regulation of T cell activation GO:0050868 25 18 1,000 2,386E-03 0,05964305 ! regulation of neuron differentiation GO:0045664 107 67 2,000 2,553E-03 0,0631402 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 2,659E-03 0,06507069 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,659E-03 0,06438574 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 23 19 1,000 2,659E-03 0,06371505 ! response to starvation GO:0042594 30 19 1,000 2,659E-03 0,0630582 ! sex determination GO:0007530 29 19 1,000 2,659E-03 0,06241475 ! regulation of catabolic process GO:0009894 106 70 2,000 2,892E-03 0,06719066 ! collagen fibril organization GO:0030199 45 20 1,000 2,947E-03 0,06778475 ! positive regulation of B cell activation GO:0050871 31 20 1,000 2,947E-03 0,06711362 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 3,249E-03 0,07325868 ! regulation of vasoconstriction GO:0019229 31 21 1,000 3,249E-03 0,07254743 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 3,386E-03 0,07487204 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 3,564E-03 0,07807726 ! protein tetramerization GO:0051262 39 22 1,000 3,564E-03 0,07734068 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 3,65E-03 0,07846553 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 3,894E-03 0,08292031 ! myelination GO:0042552 35 23 1,000 3,894E-03 0,08215957 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 3,894E-03 0,08141266 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 3,894E-03 0,08067922 ! negative regulation of catabolic process GO:0009895 34 23 1,000 3,894E-03 0,07995887 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 4,237E-03 0,08622979 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 4,237E-03 0,08547339 ! neurotransmitter secretion GO:0007269 32 24 1,000 4,237E-03 0,08473014 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 4,593E-03 0,09106529 GO:0045936|negative regulation of phosphate metabolic process, ! cyclic nucleotide biosynthetic process GO:0009190 36 25 1,000 4,593E-03 0,09028696 ! regulation of chromosome organization GO:0033044 35 25 1,000 4,593E-03 0,08952181 ! positive regulation of nuclear division GO:0051785 39 25 1,000 4,593E-03 0,08876953 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 4,593E-03 0,08802978 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 4,593E-03 0,08730226 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 4,963E-03 0,09355702 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 5,163E-03 0,09654078 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 5,346E-03 0,09915209 ! interphase GO:0051325 159 88 2,000 5,504E-03 0,10127558 ! regulation of neurogenesis GO:0050767 153 89 2,000 5,68E-03 0,10367729 ! ensheathment of neurons GO:0007272 43 28 1,000 5,742E-03 0,10398446 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 5,742E-03 0,10317208 ! regulation of B cell activation GO:0050864 42 28 1,000 5,742E-03 0,1023723 ! spindle organization GO:0007051 37 30 1,000 6,573E-03 0,11629341 ! negative regulation of cell activation GO:0050866 44 30 1,000 6,573E-03 0,11540567 ! response to light stimulus GO:0009416 153 96 2,000 7,003E-03 0,12202587 ! mammary gland development GO:0030879 57 31 1,000 7,008E-03 0,12119241 ! odontogenesis GO:0042476 50 31 1,000 7,008E-03 0,12028799 ! cell fate specification GO:0001708 37 31 1,000 7,008E-03 0,11939697 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 7,456E-03 0,12609044 ! meiosis I GO:0007127 52 32 1,000 7,456E-03 0,12517007 ! peripheral nervous system development GO:0007422 53 32 1,000 7,456E-03 0,12426304 ! calcium-mediated signaling GO:0019722 50 32 1,000 7,456E-03 0,12336906 ! extracellular structure organization GO:0043062 156 99 2,000 7,622E-03 0,1252153 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 7,916E-03 0,12912781 ! sister chromatid segregation GO:0000819 46 33 1,000 7,916E-03 0,12821846 ! carbohydrate homeostasis GO:0033500 39 33 1,000 7,916E-03 0,12732183 GO:0042593|glucose homeostasis, ! regulation of proteolysis GO:0030162 50 33 1,000 7,916E-03 0,12643765 ! hormone biosynthetic process GO:0042446 45 33 1,000 7,916E-03 0,12556566 ! cytokinesis GO:0000910 52 33 1,000 7,916E-03 0,12470562 ! polyol metabolic process GO:0019751 44 34 1,000 8,389E-03 0,13125517 ! cyclic nucleotide metabolic process GO:0009187 58 35 1,000 8,874E-03 0,13790894 ! regulation of action potential in neuron GO:0019228 54 35 1,000 8,874E-03 0,13698338 ! Rho protein signal transduction GO:0007266 51 35 1,000 8,874E-03 0,13607016 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 8,874E-03 0,13516903 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! amino acid activation GO:0043038 52 37 1,000 9,881E-03 0,14952072 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 0,01040317 0,15638745 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,01040317 0,15537195 ! maintenance of location in cell GO:0051651 69 38 1,000 0,01040317 0,15436955 ! cell growth GO:0016049 61 39 1,000 0,01093694 0,16124982 ! synapse organization GO:0050808 55 39 1,000 0,01093694 0,16022275 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,0114826 0,16715182 ! double-strand break repair GO:0006302 67 40 1,000 0,0114826 0,16610055 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01204004 0,17307557 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,01204004 0,17200056 ! positive regulation of binding GO:0051099 59 43 1,000 0,01318984 0,18726312 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,01318984 0,18611426 ! regulation of action potential GO:0001508 71 44 1,000 0,013782 0,19328409 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,013782 0,19211267 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01562632 0,21650923 ! heart morphogenesis GO:0003007 65 48 1,000 0,01626338 0,22398664 ! regulation of DNA replication GO:0006275 75 48 1,000 0,01626338 0,22265339 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01626338 0,22133591 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01691142 0,22880152 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 1,000 0,01691142 0,2274635 ! maintenance of location GO:0051235 84 49 1,000 0,01691142 0,22614104 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,01757034 0,23359409 ! lipid modification GO:0030258 73 50 1,000 0,01757034 0,2322516 ! positive regulation of growth GO:0045927 67 50 1,000 0,01757034 0,23092445 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01824005 0,23836423 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,01824005 0,23701754 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,01824005 0,23568598 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,01824005 0,2343693 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01892044 0,24176122 ! establishment of organelle localization GO:0051656 85 52 1,000 0,01892044 0,24042552 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,01961144 0,24783682 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02014461 0,25318365 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02014461 0,25180766 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02014461 0,25044653 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02014461 0,24910005 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02014461 0,24776796 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02014461 0,24645005 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02014461 0,24514608 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02014461 0,24385583 ! sleep GO:0030431 11 5 0,000 0,02014461 0,2425791 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02014461 0,24131567 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02014461 0,24006533 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02014461 0,23882788 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02014461 0,23760312 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02014461 0,23639086 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02014461 0,23519091 ! tongue development GO:0043586 6 5 0,000 0,02014461 0,23400307 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02014461 0,23282718 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02014461 0,23166304 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02014461 0,23051049 ! cobalt ion transport GO:0006824 9 5 0,000 0,02014461 0,22936935 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02014461 0,22823945 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02014461 0,22712063 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02014461 0,22601272 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02014461 0,22491558 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02014461 0,22382903 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02014461 0,22275293 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02014461 0,22168712 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02014461 0,22063147 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02014461 0,21958582 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02014461 0,21855004 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02014461 0,21752398 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02014461 0,21650752 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02014461 0,2155005 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02014461 0,21450282 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02014461 0,21351433 ! malate metabolic process GO:0006108 7 5 0,000 0,02014461 0,2125349 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02014461 0,21156442 ! behavioral response to pain GO:0048266 7 5 0,000 0,02014461 0,21060277 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02014461 0,20964981 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02014461 0,20870544 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02014461 0,20776955 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02014461 0,206842 ! mating behavior GO:0007617 6 5 0,000 0,02014461 0,2059227 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02014461 0,20501154 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02014461 0,20410841 ! rhythmic behavior GO:0007622 12 5 0,000 0,02014461 0,2032132 ! copulation GO:0007620 7 5 0,000 0,02014461 0,2023258 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02014461 0,20144612 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02014461 0,20057406 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02014461 0,19970952 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02014461 0,1988524 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02014461 0,1980026 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02014461 0,19716004 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02014461 0,19632461 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02014461 0,19549624 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02014461 0,19467483 ! response to protozoan GO:0001562 9 5 0,000 0,02014461 0,19386029 ! lymph vessel development GO:0001945 7 5 0,000 0,02014461 0,19305254 ! endochondral ossification GO:0001958 12 5 0,000 0,02014461 0,19225149 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02014461 0,19145706 ! parathyroid gland development GO:0060017 8 5 0,000 0,02014461 0,19066917 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02014461 0,18988774 ! anagen GO:0042640 6 5 0,000 0,02014461 0,18911269 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02014461 0,18834394 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02014461 0,18758141 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02014461 0,18682503 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02014461 0,18607473 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02014461 0,18533043 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02014461 0,18459207 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02014461 0,18385956 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02014461 0,18313284 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02014461 0,18241184 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02014461 0,1816965 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02014461 0,18098675 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02014461 0,18028252 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02014461 0,17958375 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02014461 0,17889038 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02014461 0,17820234 ! ovulation GO:0030728 6 5 0,000 0,02014461 0,17751957 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02014461 0,17684202 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02014461 0,17616961 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02014461 0,17550231 ! response to pH GO:0009268 9 5 0,000 0,02014461 0,17484003 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02014461 0,17418274 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02014461 0,17353037 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02014461 0,17288287 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02014461 0,17224018 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02014461 0,17160225 ! polyol catabolic process GO:0046174 7 5 0,000 0,02014461 0,17096904 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02014461 0,17034047 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02014461 0,16971651 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02014461 0,16909711 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02014461 0,16848221 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02014461 0,16787177 ! urea metabolic process GO:0019627 6 5 0,000 0,02014461 0,16726573 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02014461 0,16666406 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02014461 0,1660667 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02014461 0,1654736 ! neutrophil activation GO:0042119 5 5 0,000 0,02014461 0,16488473 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02014461 0,16430003 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02014461 0,16371946 ! response to food GO:0032094 5 5 0,000 0,02014461 0,16314299 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02014461 0,16257056 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02014461 0,16200213 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02014461 0,16143766 ! forebrain neuron development GO:0021884 7 5 0,000 0,02014461 0,16087711 ! melanosome organization GO:0032438 7 5 0,000 0,02014461 0,16032044 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02014461 0,15976762 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02014461 0,15921859 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02014461 0,15867332 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02014461 0,15813177 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02014461 0,15759391 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02014461 0,15705969 ! nucleoside transport GO:0015858 6 5 0,000 0,02014461 0,15652908 ! nucleoside salvage GO:0043174 7 5 0,000 0,02014461 0,15600205 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02014461 0,15547855 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02014461 0,15495856 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02014461 0,15444203 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02014461 0,15392893 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02014461 0,15341923 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02014461 0,1529129 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02014461 0,1524099 ! depyrimidination GO:0045008 8 5 0,000 0,02014461 0,15191019 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02014461 0,15141375 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02014461 0,15092055 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02014461 0,15043055 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02014461 0,14994372 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02014461 0,14946003 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02014461 0,14897945 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02014461 0,14850195 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02014461 0,1480275 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02014461 0,14755608 ! monocyte differentiation GO:0030224 8 5 0,000 0,02014461 0,14708765 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02014461 0,14662218 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02014461 0,14615965 ! centrosome duplication GO:0051298 5 5 0,000 0,02014461 0,14570003 ! response to UV-C GO:0010225 6 5 0,000 0,02014461 0,14524329 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02014461 0,1447894 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02014461 0,14433834 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02014461 0,14389009 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02014461 0,14344461 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02014461 0,14300188 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02014461 0,14256187 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02014461 0,14212457 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02014461 0,14168993 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02014461 0,14125795 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02014461 0,1408286 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02014461 0,14040184 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02014461 0,13997767 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02014461 0,13955605 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02014461 0,13913696 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02014461 0,13872038 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02014461 0,13830629 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02014461 0,13789467 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02014461 0,13748549 ! neural tube patterning GO:0021532 6 5 0,000 0,02014461 0,13707872 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02014461 0,13667436 ! histone demethylation GO:0016577 9 5 0,000 0,02014461 0,13627238 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02014461 0,13587275 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02014461 0,13547546 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02014461 0,13508049 ! enteric nervous system development GO:0048484 8 5 0,000 0,02014461 0,13468782 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02014461 0,13429742 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02014461 0,13390927 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02014461 0,13352337 ! transcription termination GO:0006353 8 5 0,000 0,02014461 0,13313968 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02014461 0,13275819 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02014461 0,13237888 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02014461 0,13200173 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02014461 0,13162673 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02014461 0,13125385 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02014461 0,13088307 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02014461 0,13051439 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02014461 0,13014778 ! apical protein localization GO:0045176 6 5 0,000 0,02014461 0,12978322 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02014461 0,12942069 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02014461 0,12906019 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02014461 0,12870169 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02014461 0,12834518 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02014461 0,12799063 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02014461 0,12763804 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02014461 0,12728739 ! glial cell migration GO:0008347 10 5 0,000 0,02014461 0,12693865 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02014461 0,12659183 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02014461 0,12624689 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02014461 0,12590383 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02014461 0,12556262 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02014461 0,12522327 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02014461 0,12488574 ! neural plate development GO:0001840 6 5 0,000 0,02014461 0,12455002 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02014461 0,12421611 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02014461 0,12388398 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02014461 0,12355362 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02014461 0,12322502 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02014461 0,12289817 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02014461 0,12257304 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02014461 0,12224963 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02014461 0,12192792 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02014461 0,1216079 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02014461 0,12128955 ! spindle assembly GO:0051225 5 5 0,000 0,02014461 0,12097287 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02014461 0,12065783 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02014461 0,12034444 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02014461 0,12003266 ! organ regeneration GO:0031100 7 5 0,000 0,02014461 0,1197225 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02014461 0,11941394 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02014461 0,11910696 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02014461 0,11880156 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02014461 0,11849772 GO:0055081|anion homeostasis, ! regulation of mitosis GO:0007088 84 54 1,000 0,02031293 0,119183 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,02031293 0,11887973 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,02031293 0,11857801 ! chromosome segregation GO:0007059 83 57 1,000 0,02247947 0,1308931 ! viral reproductive process GO:0022415 87 58 1,000 0,02322202 0,1348754 ! activation of MAPK activity GO:0000187 84 59 1,000 0,02397462 0,13889577 ! lung development GO:0030324 94 59 1,000 0,02397462 0,13854678 ! nucleoside monophosphate metabolic process GO:0009123 95 59 1,000 0,02397462 0,13819955 ! tRNA transcription GO:0009304 11 6 0,000 0,02412526 0,13872023 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02412526 0,13837429 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02412526 0,13803008 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02412526 0,13768757 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02412526 0,13734676 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02412526 0,13700763 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02412526 0,13667018 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02412526 0,13633438 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02412526 0,13600023 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02412526 0,13566771 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02412526 0,13533681 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02412526 0,13500752 ! prostate gland development GO:0030850 9 6 0,000 0,02412526 0,13467983 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02412526 0,13435373 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02412526 0,13402921 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02412526 0,13370625 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02412526 0,13338484 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02412526 0,13306497 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02412526 0,13274663 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02412526 0,13242981 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02412526 0,1321145 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02412526 0,13180069 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02412526 0,13148837 ! neuron adhesion GO:0007158 9 6 0,000 0,02412526 0,13117752 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,02412526 0,13086814 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02412526 0,13056022 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02412526 0,13025374 ! signal peptide processing GO:0006465 8 6 0,000 0,02412526 0,12994869 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02412526 0,12964507 ! mRNA stabilization GO:0048255 15 6 0,000 0,02412526 0,12934287 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02412526 0,12904207 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02412526 0,12874267 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02412526 0,12844466 ! opsonization GO:0008228 8 6 0,000 0,02412526 0,12814802 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02412526 0,12785275 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02412526 0,12755883 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02412526 0,12726627 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02412526 0,12697504 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02412526 0,12668514 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02412526 0,12639656 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02412526 0,1261093 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02412526 0,12582334 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02412526 0,12553867 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02412526 0,12525529 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02412526 0,12497318 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02412526 0,12469234 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02412526 0,12441276 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02412526 0,12413443 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02412526 0,12385735 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02412526 0,1235815 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02412526 0,12330687 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02412526 0,12303346 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02412526 0,12276127 ! thymic T cell selection GO:0045061 12 6 0,000 0,02412526 0,12249027 ! protein lipoylation GO:0009249 10 6 0,000 0,02412526 0,12222047 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02412526 0,12195185 ! pigment granule organization GO:0048753 11 6 0,000 0,02412526 0,12168441 ! drug transport GO:0015893 6 6 0,000 0,02412526 0,12141814 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02412526 0,12115304 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02412526 0,12088909 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02412526 0,12062629 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02412526 0,12036462 ! histidine metabolic process GO:0006547 6 6 0,000 0,02412526 0,1201041 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02412526 0,11984469 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02412526 0,11958641 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02412526 0,11932923 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02412526 0,11907316 ! adenohypophysis development GO:0021984 10 6 0,000 0,02412526 0,11881818 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02412526 0,1185643 ! hyperosmotic response GO:0006972 8 6 0,000 0,02412526 0,1183115 ! microtubule nucleation GO:0007020 10 6 0,000 0,02412526 0,11805977 ! ER overload response GO:0006983 7 6 0,000 0,02412526 0,11780911 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02412526 0,11755952 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02412526 0,11731098 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02412526 0,11706349 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02412526 0,11681704 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02412526 0,11657162 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02412526 0,11632724 ! response to dietary excess GO:0002021 7 6 0,000 0,02412526 0,11608387 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02412526 0,11584153 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02412526 0,11560019 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02412526 0,11535986 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02412526 0,11512052 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02412526 0,11488218 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02412526 0,11464482 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02412526 0,11440844 ! neuron apoptosis GO:0051402 8 6 0,000 0,02412526 0,11417303 ! organic alcohol transport GO:0015850 9 6 0,000 0,02412526 0,11393859 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02412526 0,11370511 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02412526 0,11347258 ! carnitine transport GO:0015879 8 6 0,000 0,02412526 0,113241 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02412526 0,11301037 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02412526 0,11278067 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02412526 0,11255191 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02412526 0,11232407 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02412526 0,11209716 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02412526 0,11187115 ! parturition GO:0007567 12 6 0,000 0,02412526 0,11164606 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02412526 0,11142187 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02412526 0,11119858 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02412526 0,11097618 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02412526 0,11075467 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02412526 0,11053405 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02412526 0,1103143 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02412526 0,11009542 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02412526 0,10987741 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02412526 0,10966026 ! macrophage differentiation GO:0030225 10 6 0,000 0,02412526 0,10944397 ! astrocyte development GO:0014002 14 6 0,000 0,02412526 0,10922853 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02412526 0,10901393 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02412526 0,10880018 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02412526 0,10858726 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02412526 0,10837518 ! eating behavior GO:0042755 6 6 0,000 0,02412526 0,10816392 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02412526 0,10795349 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02412526 0,10774387 ! response to copper ion GO:0046688 9 6 0,000 0,02412526 0,10753506 ! DNA topological change GO:0006265 8 6 0,000 0,02412526 0,10732706 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02412526 0,10711987 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02412526 0,10691347 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02412526 0,10670787 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02412526 0,10650306 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02412526 0,10629903 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02412526 0,10609578 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02412526 0,10589331 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02412526 0,1056916 ! gas homeostasis GO:0033483 11 6 0,000 0,02412526 0,10549067 ! hair follicle maturation GO:0048820 7 6 0,000 0,02412526 0,1052905 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02412526 0,10509108 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02412526 0,10489242 ! Schwann cell development GO:0014044 14 6 0,000 0,02412526 0,10469451 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02412526 0,10449735 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02412526 0,10430092 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02412526 0,10410524 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02412526 0,10391028 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02412526 0,10371606 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02412526 0,10352256 ! histone ubiquitination GO:0016574 7 6 0,000 0,02412526 0,10332978 ! regulation of meiosis GO:0040020 10 6 0,000 0,02412526 0,10313772 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02412526 0,10294637 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02412526 0,10275573 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02412526 0,10256579 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02412526 0,10237655 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02412526 0,10218801 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02412526 0,10200017 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02412526 0,10181301 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02412526 0,10162654 ! receptor internalization GO:0031623 9 6 0,000 0,02412526 0,10144075 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02412526 0,10125564 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02412526 0,10107121 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02412526 0,10088744 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02412526 0,10070434 ! protein deubiquitination GO:0016579 8 6 0,000 0,02412526 0,10052191 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02412526 0,10034013 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02412526 0,10015901 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02412526 0,09997854 ! axonal fasciculation GO:0007413 9 6 0,000 0,02412526 0,09979873 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02412526 0,09961955 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02412526 0,09944103 ! midbrain development GO:0030901 6 6 0,000 0,02412526 0,09926313 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02412526 0,09908588 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02412526 0,09890925 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02412526 0,09873326 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02412526 0,09855789 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02412526 0,09838314 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02412526 0,09820901 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02412526 0,0980355 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02412526 0,0978626 ! adult feeding behavior GO:0008343 6 6 0,000 0,02412526 0,0976903 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02412526 0,09751862 ! blastocyst growth GO:0001832 15 6 0,000 0,02412526 0,09734753 ! pigment granule transport GO:0051904 12 6 0,000 0,02412526 0,09717704 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02412526 0,09700715 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02412526 0,09683786 ! catecholamine transport GO:0051937 7 6 0,000 0,02412526 0,09666915 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02412526 0,09650103 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02412526 0,09633349 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02412526 0,09616654 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02412526 0,09600016 ! protein prenylation GO:0018342 10 6 0,000 0,02412526 0,09583436 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02412526 0,09566912 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02412526 0,09550446 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02412526 0,09534036 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02412526 0,09517683 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02412526 0,09501386 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,02473715 0,09725719 ! extracellular matrix organization GO:0030198 103 61 1,000 0,02550954 0,10012278 ! neurotransmitter transport GO:0006836 81 62 1,000 0,0262917 0,10301687 ! cellular hormone metabolic process GO:0034754 87 62 1,000 0,0262917 0,10284167 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,0262917 0,10266706 ! respiratory tube development GO:0030323 99 62 1,000 0,0262917 0,10249305 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,02708352 0,10540118 ! viral reproduction GO:0016032 92 63 1,000 0,02708352 0,10522314 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02708352 0,1050457 ! negative regulation of cell size GO:0045792 108 64 1,000 0,02788493 0,10797196 ! respiratory system development GO:0060541 100 64 1,000 0,02788493 0,10779049 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02808996 0,10840084 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02808996 0,10821927 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02808996 0,1080383 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02808996 0,10785794 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02808996 0,10767817 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02808996 0,10749901 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02808996 0,10732044 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02808996 0,10714246 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02808996 0,10696507 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02808996 0,10678827 ! reproductive behavior GO:0019098 12 7 0,000 0,02808996 0,10661205 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02808996 0,10643641 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02808996 0,10626135 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02808996 0,10608687 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02808996 0,10591296 ! oligopeptide transport GO:0006857 11 7 0,000 0,02808996 0,10573961 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02808996 0,10556684 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02808996 0,10539462 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02808996 0,10522297 ! RNA methylation GO:0001510 11 7 0,000 0,02808996 0,10505188 ! pericardium development GO:0060039 8 7 0,000 0,02808996 0,10488134 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02808996 0,10471135 ! fibril organization GO:0043206 13 7 0,000 0,02808996 0,10454191 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02808996 0,10437303 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02808996 0,10420468 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02808996 0,10403688 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02808996 0,10386962 ! lipoprotein transport GO:0042953 9 7 0,000 0,02808996 0,10370289 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02808996 0,1035367 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02808996 0,10337105 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02808996 0,10320592 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02808996 0,10304131 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02808996 0,10287723 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02808996 0,10271368 ! chemosensory behavior GO:0007635 9 7 0,000 0,02808996 0,10255064 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02808996 0,10238812 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02808996 0,10222611 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02808996 0,10206462 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02808996 0,10190363 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02808996 0,10174315 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02808996 0,10158318 ! reflex GO:0060004 12 7 0,000 0,02808996 0,10142371 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02808996 0,10126474 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02808996 0,10110626 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02808996 0,10094829 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02808996 0,1007908 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02808996 0,10063381 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02808996 0,1004773 ! spinal cord patterning GO:0021511 7 7 0,000 0,02808996 0,10032128 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02808996 0,10016574 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02808996 0,10001069 ! adrenal gland development GO:0030325 17 7 0,000 0,02808996 0,09985611 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02808996 0,09970201 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02808996 0,09954839 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02808996 0,09939524 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02808996 0,09924255 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02808996 0,09909034 ! endosome organization GO:0007032 10 7 0,000 0,02808996 0,0989386 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02808996 0,09878731 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02808996 0,09863649 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02808996 0,09848613 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02808996 0,09833623 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02808996 0,09818678 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02808996 0,09803779 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02808996 0,09788925 ! galactose metabolic process GO:0006012 10 7 0,000 0,02808996 0,09774115 ! vesicle fusion GO:0006906 15 7 0,000 0,02808996 0,09759351 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02808996 0,09744631 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02808996 0,09729955 ! organ growth GO:0035265 11 7 0,000 0,02808996 0,09715324 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02808996 0,09700736 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02808996 0,09686192 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02808996 0,09671692 ! retinol metabolic process GO:0042572 9 7 0,000 0,02808996 0,09657235 ! behavioral fear response GO:0001662 13 7 0,000 0,02808996 0,09642821 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02808996 0,09628451 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02808996 0,09614123 ! rRNA modification GO:0000154 12 7 0,000 0,02808996 0,09599837 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02808996 0,09585594 ! response to UV-B GO:0010224 11 7 0,000 0,02808996 0,09571393 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,02808996 0,09557234 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02808996 0,09543117 ! intermediate filament organization GO:0045109 11 7 0,000 0,02808996 0,09529042 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02808996 0,09515008 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02808996 0,09501015 ! fibrinolysis GO:0042730 9 7 0,000 0,02808996 0,09487064 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02808996 0,09473153 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02808996 0,09459283 ! B cell lineage commitment GO:0002326 17 7 0,000 0,02808996 0,09445454 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02808996 0,09431665 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02808996 0,09417916 ! response to tropane GO:0014073 13 7 0,000 0,02808996 0,09404207 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02808996 0,09390538 ! melanosome localization GO:0032400 10 7 0,000 0,02808996 0,09376909 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02808996 0,09363319 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02808996 0,09349769 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02808996 0,09336258 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02808996 0,09322785 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02808996 0,09309352 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02808996 0,09295957 ! mast cell activation GO:0045576 9 7 0,000 0,02808996 0,09282601 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02808996 0,09269283 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02808996 0,09256003 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02808996 0,09242762 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02808996 0,09229558 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02808996 0,09216391 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02808996 0,09203263 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02808996 0,09190171 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02808996 0,09177117 ! T cell lineage commitment GO:0002360 12 7 0,000 0,02808996 0,091641 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02808996 0,09151119 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02808996 0,09138176 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02808996 0,09125269 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02808996 0,09112398 ! response to tumor cell GO:0002347 12 7 0,000 0,02808996 0,09099564 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02808996 0,09086766 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02808996 0,09074003 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02808996 0,09061277 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02808996 0,09048586 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02808996 0,09035931 ! diuresis GO:0030146 12 7 0,000 0,02808996 0,09023311 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02808996 0,09010726 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02808996 0,08998176 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02808996 0,08985661 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02808996 0,08973181 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02808996 0,08960736 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02808996 0,08948325 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02808996 0,08935948 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02808996 0,08923605 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02808996 0,08911297 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02808996 0,08899022 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02808996 0,08886782 ! lymph node development GO:0048535 9 7 0,000 0,02808996 0,08874575 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02808996 0,08862401 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02808996 0,08850261 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02808996 0,08838154 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02808996 0,0882608 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02808996 0,08814039 ! ATP catabolic process GO:0006200 10 7 0,000 0,02808996 0,0880203 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02808996 0,08790055 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02808996 0,08778112 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02808996 0,08766201 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02808996 0,08754323 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02808996 0,08742477 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02808996 0,08730663 ! muscle adaptation GO:0043500 12 7 0,000 0,02808996 0,0871888 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02808996 0,0870713 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02808996 0,08695411 ! retina homeostasis GO:0001895 9 7 0,000 0,02808996 0,08683724 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02808996 0,08672068 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02808996 0,08660443 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02808996 0,08648849 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02808996 0,08637287 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02808996 0,08625755 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02808996 0,08614254 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02808996 0,08602783 ! protein oligomerization GO:0051259 100 65 1,000 0,02869584 0,08776652 ! axon guidance GO:0007411 99 66 1,000 0,02951615 0,09015557 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,03203266 0,09771237 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03203878 0,09760157 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03203878 0,09747247 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,03203878 0,09734371 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03203878 0,09721529 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03203878 0,0970872 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03203878 0,09695946 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03203878 0,09683205 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03203878 0,09670497 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03203878 0,09657823 ! phosphate transport GO:0006817 10 8 0,000 0,03203878 0,09645182 ! N-glycan processing GO:0006491 12 8 0,000 0,03203878 0,09632573 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03203878 0,09619998 ! UTP metabolic process GO:0046051 8 8 0,000 0,03203878 0,09607456 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03203878 0,09594946 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03203878 0,09582469 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,03203878 0,09570024 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03203878 0,09557612 ! succinate metabolic process GO:0006105 14 8 0,000 0,03203878 0,09545231 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,03203878 0,09532883 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03203878 0,09520567 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03203878 0,09508282 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03203878 0,09496029 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,03203878 0,09483808 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03203878 0,09471618 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03203878 0,09459459 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03203878 0,09447332 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03203878 0,09435235 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03203878 0,0942317 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03203878 0,09411135 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03203878 0,09399131 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03203878 0,09387158 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03203878 0,09375215 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03203878 0,09363302 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03203878 0,0935142 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03203878 0,09339567 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03203878 0,09327745 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03203878 0,09315953 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03203878 0,0930419 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03203878 0,09292457 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03203878 0,09280754 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03203878 0,0926908 ! melanin metabolic process GO:0006582 12 8 0,000 0,03203878 0,09257436 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03203878 0,0924582 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03203878 0,09234234 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,03203878 0,09222677 ! macrophage activation GO:0042116 12 8 0,000 0,03203878 0,09211148 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03203878 0,09199649 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03203878 0,09188178 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03203878 0,09176736 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03203878 0,09165322 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03203878 0,09153936 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03203878 0,09142579 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03203878 0,0913125 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03203878 0,09119949 ! ruffle organization GO:0031529 11 8 0,000 0,03203878 0,09108676 ! osteoblast development GO:0002076 13 8 0,000 0,03203878 0,09097431 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03203878 0,09086213 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03203878 0,09075023 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03203878 0,09063861 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03203878 0,09052726 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03203878 0,09041618 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03203878 0,09030538 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03203878 0,09019484 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03203878 0,09008458 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03203878 0,08997459 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03203878 0,08986486 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03203878 0,0897554 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03203878 0,08964621 ! segment specification GO:0007379 10 8 0,000 0,03203878 0,08953729 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03203878 0,08942863 ! cellular extravasation GO:0045123 11 8 0,000 0,03203878 0,08932023 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03203878 0,08921209 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03203878 0,08910422 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03203878 0,0889966 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03203878 0,08888925 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03203878 0,08878215 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03203878 0,08867532 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03203878 0,08856873 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03203878 0,08846241 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03203878 0,08835634 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03203878 0,08825052 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03203878 0,08814496 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03203878 0,08803965 ! icosanoid secretion GO:0032309 12 8 0,000 0,03203878 0,08793459 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03203878 0,08782978 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03203878 0,08772522 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03203878 0,08762091 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03203878 0,08751685 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03203878 0,08741303 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03203878 0,08730946 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03203878 0,08720614 ! sterol catabolic process GO:0016127 9 8 0,000 0,03203878 0,08710306 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03203878 0,08700022 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03203878 0,08689763 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03203878 0,08679527 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03203878 0,08669316 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03203878 0,08659129 ! prophase GO:0051324 11 8 0,000 0,03203878 0,08648966 ! S phase GO:0051320 8 8 0,000 0,03203878 0,08638826 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03203878 0,0862871 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03203878 0,08618618 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03203878 0,0860855 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03203878 0,08598505 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03203878 0,08588483 ! hormone catabolic process GO:0042447 13 8 0,000 0,03203878 0,08578485 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03203878 0,0856851 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03203878 0,08558558 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03203878 0,0854863 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03203878 0,08538724 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03203878 0,08528841 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03203878 0,08518981 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03203878 0,08509144 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03203878 0,0849933 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03203878 0,08489538 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03203878 0,08479768 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03203878 0,08470022 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03203878 0,08460297 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03203878 0,08450595 GO:0000076|DNA replication checkpoint, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,03203878 0,08440915 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,03288974 0,08655195 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,03288974 0,08645303 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,03375579 0,08862822 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,03375579 0,08852716 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,03463073 0,09071832 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,03463073 0,09061511 ! regulation of blood pressure GO:0008217 107 73 1,000 0,03551448 0,09282194 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03597178 0,09391043 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03597178 0,09380395 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03597178 0,09369772 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03597178 0,09359173 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03597178 0,09348597 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03597178 0,09338046 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03597178 0,09327518 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03597178 0,09317014 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03597178 0,09306534 ! GTP metabolic process GO:0046039 9 9 0,000 0,03597178 0,09296077 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03597178 0,09285644 ! social behavior GO:0035176 14 9 0,000 0,03597178 0,09275234 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03597178 0,09264847 ! artery development GO:0060840 19 9 0,000 0,03597178 0,09254484 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03597178 0,09244144 ! response to pain GO:0048265 16 9 0,000 0,03597178 0,09233827 ! protein complex disassembly GO:0043241 17 9 0,000 0,03597178 0,09223533 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03597178 0,09213261 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03597178 0,09203013 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03597178 0,09192788 ! lung alveolus development GO:0048286 17 9 0,000 0,03597178 0,09182585 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03597178 0,09172404 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03597178 0,09162247 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03597178 0,09152111 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03597178 0,09141999 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03597178 0,09131908 ! protein targeting to ER GO:0045047 19 9 0,000 0,03597178 0,0912184 ! T cell selection GO:0045058 18 9 0,000 0,03597178 0,09111794 ! endoderm development GO:0007492 12 9 0,000 0,03597178 0,0910177 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03597178 0,09091768 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03597178 0,09081788 ! arginine catabolic process GO:0006527 10 9 0,000 0,03597178 0,0907183 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03597178 0,09061894 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03597178 0,09051979 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03597178 0,09042086 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03597178 0,09032215 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03597178 0,09022365 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03597178 0,09012537 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03597178 0,0900273 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03597178 0,08992944 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03597178 0,0898318 ! mannose metabolic process GO:0006013 9 9 0,000 0,03597178 0,08973437 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03597178 0,08963715 ! receptor clustering GO:0043113 15 9 0,000 0,03597178 0,08954014 ! epithelial cell development GO:0002064 10 9 0,000 0,03597178 0,08944334 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03597178 0,08934675 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03597178 0,08925036 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03597178 0,08915419 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03597178 0,08905822 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03597178 0,08896246 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03597178 0,0888669 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03597178 0,08877155 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03597178 0,08867641 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03597178 0,08858146 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03597178 0,08848672 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03597178 0,08839219 ! DNA ligation GO:0006266 14 9 0,000 0,03597178 0,08829785 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03597178 0,08820372 ! response to amine stimulus GO:0014075 13 9 0,000 0,03597178 0,08810978 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03597178 0,08801605 ! erythrocyte development GO:0048821 11 9 0,000 0,03597178 0,08792252 ! renal water homeostasis GO:0003091 14 9 0,000 0,03597178 0,08782918 ! postreplication repair GO:0006301 11 9 0,000 0,03597178 0,08773604 ! mRNA cleavage GO:0006379 13 9 0,000 0,03597178 0,0876431 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03597178 0,08755036 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03597178 0,08745781 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03597178 0,08736546 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03597178 0,0872733 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03597178 0,08718134 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03597178 0,08708957 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03597178 0,08699799 ! acid secretion GO:0046717 14 9 0,000 0,03597178 0,0869066 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03597178 0,08681541 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03597178 0,08672441 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03597178 0,0866336 ! purine base metabolic process GO:0006144 18 9 0,000 0,03597178 0,08654298 ! oocyte differentiation GO:0009994 12 9 0,000 0,03597178 0,08645255 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03597178 0,0863623 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03597178 0,08627225 ! spleen development GO:0048536 15 9 0,000 0,03597178 0,08618238 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03597178 0,0860927 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03597178 0,08600321 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03597178 0,0859139 ! detection of calcium ion GO:0005513 13 9 0,000 0,03597178 0,08582478 ! blastocyst formation GO:0001825 12 9 0,000 0,03597178 0,08573584 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03597178 0,08564709 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03597178 0,08555852 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03597178 0,08547013 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03597178 0,08538193 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03597178 0,0852939 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03597178 0,08520606 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03597178 0,0851184 ! prepulse inhibition GO:0060134 14 9 0,000 0,03597178 0,08503092 ! embryonic placenta development GO:0001892 12 9 0,000 0,03597178 0,08494362 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03597178 0,0848565 ! insulin secretion GO:0030073 17 9 0,000 0,03597178 0,08476956 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03597178 0,08468279 ! response to nicotine GO:0035094 16 9 0,000 0,03597178 0,0845962 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03597178 0,08450979 ! nucleus localization GO:0051647 15 9 0,000 0,03597178 0,08442356 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03597178 0,0843375 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,03640695 0,08527086 ! negative regulation of growth GO:0045926 123 75 1,000 0,03730806 0,08729251 ! tRNA metabolic process GO:0006399 95 76 1,000 0,03821773 0,08933006 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03913587 0,09138325 ! gland development GO:0048732 148 77 1,000 0,03913587 0,09129057 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03988902 0,09295314 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03988902 0,09285906 ! neuron fate specification GO:0048665 11 10 0,000 0,03988902 0,09276517 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03988902 0,09267146 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03988902 0,09257795 ! thyroid gland development GO:0030878 19 10 0,000 0,03988902 0,09248463 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03988902 0,09239149 ! synapsis GO:0007129 13 10 0,000 0,03988902 0,09229854 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03988902 0,09220578 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03988902 0,0921132 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03988902 0,09202081 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03988902 0,09192861 ! sulfate transport GO:0008272 12 10 0,000 0,03988902 0,09183659 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03988902 0,09174475 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03988902 0,0916531 ! androgen metabolic process GO:0008209 13 10 0,000 0,03988902 0,09156163 ! phospholipid efflux GO:0033700 16 10 0,000 0,03988902 0,09147034 ! hippocampus development GO:0021766 19 10 0,000 0,03988902 0,09137923 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03988902 0,09128831 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03988902 0,09119756 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03988902 0,091107 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03988902 0,09101662 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03988902 0,09092641 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03988902 0,09083639 ! pathogenesis GO:0009405 13 10 0,000 0,03988902 0,09074654 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03988902 0,09065687 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03988902 0,09056737 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03988902 0,09047806 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03988902 0,09038892 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03988902 0,09029995 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03988902 0,09021116 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03988902 0,09012254 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03988902 0,0900341 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03988902 0,08994583 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03988902 0,08985774 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03988902 0,08976981 ! response to X-ray GO:0010165 16 10 0,000 0,03988902 0,08968206 ! B cell proliferation GO:0042100 14 10 0,000 0,03988902 0,08959448 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03988902 0,08950707 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03988902 0,08941983 ! forebrain cell migration GO:0021885 17 10 0,000 0,03988902 0,08933276 ! lipid digestion GO:0044241 15 10 0,000 0,03988902 0,08924586 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03988902 0,08915913 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03988902 0,08907257 ! UV protection GO:0009650 14 10 0,000 0,03988902 0,08898618 ! entry into host cell GO:0030260 20 10 0,000 0,03988902 0,08889995 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03988902 0,08881389 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03988902 0,088728 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03988902 0,08864227 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03988902 0,08855671 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03988902 0,08847131 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03988902 0,08838608 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03988902 0,08830101 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03988902 0,0882161 ! regulation of organ growth GO:0046620 11 10 0,000 0,03988902 0,08813136 ! response to dsRNA GO:0043331 18 10 0,000 0,03988902 0,08804678 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03988902 0,08796237 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03988902 0,08787811 ! embryonic axis specification GO:0000578 12 10 0,000 0,03988902 0,08779402 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03988902 0,08771008 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03988902 0,08762631 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03988902 0,0875427 ! cranial nerve development GO:0021545 12 10 0,000 0,03988902 0,08745925 ! fucose catabolic process GO:0019317 16 10 0,000 0,03988902 0,08737595 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03988902 0,08729282 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03988902 0,08720984 ! protein sumoylation GO:0016925 12 10 0,000 0,03988902 0,08712702 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03988902 0,08704435 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03988902 0,08696185 ! zymogen activation GO:0031638 14 10 0,000 0,03988902 0,0868795 ! salivary gland development GO:0007431 22 10 0,000 0,03988902 0,0867973 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03988902 0,08671526 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03988902 0,08663338 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03988902 0,08655165 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03988902 0,08647007 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03988902 0,08638865 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03988902 0,08630738 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03988902 0,08622627 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03988902 0,0861453 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03988902 0,08606449 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03988902 0,08598383 ! detection of bacterium GO:0016045 10 10 0,000 0,03988902 0,08590332 ! embryonic gut development GO:0048566 11 10 0,000 0,03988902 0,08582296 ! activation of innate immune response GO:0002218 10 10 0,000 0,03988902 0,08574276 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03988902 0,0856627 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03988902 0,08558279 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03988902 0,08550303 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03988902 0,08542342 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03988902 0,08534395 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03988902 0,08526464 ! chromatin assembly GO:0031497 102 80 1,000 0,04194033 0,08956617 GO:0006334|nucleosome assembly, ! regulation of cell cycle process GO:0010564 122 81 1,000 0,04289156 0,09151261 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,04289156 0,0914278 GO:0002696|positive regulation of leukocyte activation, ! rRNA transcription GO:0009303 17 11 0,000 0,04379057 0,0932577 ! respiratory burst GO:0045730 14 11 0,000 0,04379057 0,09317143 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04379057 0,09308532 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04379057 0,09299937 ! filopodium assembly GO:0046847 19 11 0,000 0,04379057 0,09291357 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04379057 0,09282794 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04379057 0,09274246 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,04379057 0,09265714 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,04379057 0,09257198 ! mating GO:0007618 14 11 0,000 0,04379057 0,09248697 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04379057 0,09240212 ! T cell proliferation GO:0042098 20 11 0,000 0,04379057 0,09231743 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04379057 0,09223289 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,04379057 0,0921485 ! bone resorption GO:0045453 16 11 0,000 0,04379057 0,09206427 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04379057 0,0919802 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04379057 0,09189627 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! regulation of mRNA processing GO:0050684 18 11 0,000 0,04379057 0,0918125 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04379057 0,09172888 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04379057 0,09164542 ! syncytium formation GO:0006949 15 11 0,000 0,04379057 0,0915621 ! plasma membrane organization GO:0007009 18 11 0,000 0,04379057 0,09147894 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04379057 0,09139593 ! focal adhesion formation GO:0048041 24 11 0,000 0,04379057 0,09131307 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04379057 0,09123036 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04379057 0,0911478 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,04379057 0,09106538 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04379057 0,09098312 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04379057 0,09090101 ! adult heart development GO:0007512 11 11 0,000 0,04379057 0,09081904 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04379057 0,09073722 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04379057 0,09065555 ! temperature homeostasis GO:0001659 16 11 0,000 0,04379057 0,09057402 ! L-glutamate transport GO:0015813 16 11 0,000 0,04379057 0,09049264 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04379057 0,09041141 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04379057 0,09033033 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04379057 0,09024938 ! stem cell development GO:0048864 29 11 0,000 0,04379057 0,09016859 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,04379057 0,09008794 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04379057 0,09000743 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,04379057 0,08992707 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04379057 0,08984685 ! vasoconstriction GO:0042310 15 11 0,000 0,04379057 0,08976677 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04379057 0,08968683 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04379057 0,08960704 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04379057 0,08952739 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04379057 0,08944788 ! ribosome assembly GO:0042255 13 11 0,000 0,04379057 0,08936851 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04379057 0,08928929 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04379057 0,0892102 ! chromatin silencing GO:0006342 19 11 0,000 0,04379057 0,08913125 ! nucleosome positioning GO:0016584 13 11 0,000 0,04379057 0,08905244 ! T cell homeostasis GO:0043029 20 11 0,000 0,04379057 0,08897378 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04379057 0,08889525 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,04379057 0,08881686 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04379057 0,0887386 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04379057 0,08866049 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04379057 0,08858251 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04379057 0,08850467 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,04379057 0,08842697 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04379057 0,0883494 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04379057 0,08827197 ! male genitalia development GO:0030539 13 11 0,000 0,04379057 0,08819467 ! cholesterol efflux GO:0033344 19 11 0,000 0,04379057 0,08811751 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04379057 0,08804048 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04379057 0,08796359 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04379057 0,08788684 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04379057 0,08781021 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04379057 0,08773372 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04379057 0,08765737 ! defense response to fungus GO:0050832 12 11 0,000 0,04379057 0,08758114 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04379057 0,08750505 ! lysogeny GO:0030069 18 11 0,000 0,04379057 0,08742909 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04379057 0,08735326 ! acrosome reaction GO:0007340 13 11 0,000 0,04379057 0,08727757 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04379057 0,087202 ! ossification GO:0001503 134 82 1,000 0,04385086 0,08724653 GO:0060348|bone development, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,04481816 0,089094 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,04579336 0,090954 ! protein-DNA complex assembly GO:0065004 107 84 1,000 0,04579336 0,09087553 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,04677641 0,09274632 ! rRNA metabolic process GO:0016072 107 85 1,000 0,04677641 0,09266644 GO:0006364|rRNA processing, ! regulation of membrane potential GO:0042391 128 85 1,000 0,04677641 0,09258669 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,04677641 0,09250708 ! lactation GO:0007595 20 12 0,000 0,04767649 0,09420612 ! reproductive cellular process GO:0048610 14 12 0,000 0,04767649 0,09412526 ! tRNA modification GO:0006400 14 12 0,000 0,04767649 0,09404453 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04767649 0,09396395 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04767649 0,0938835 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04767649 0,09380319 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04767649 0,09372301 ! non-recombinational repair GO:0000726 19 12 0,000 0,04767649 0,09364298 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04767649 0,09356308 ! peroxisomal transport GO:0043574 21 12 0,000 0,04767649 0,09348331 ! cartilage condensation GO:0001502 18 12 0,000 0,04767649 0,09340368 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04767649 0,09332419 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04767649 0,09324483 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04767649 0,09316561 ! heart looping GO:0001947 15 12 0,000 0,04767649 0,09308652 ! palate development GO:0060021 15 12 0,000 0,04767649 0,09300757 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04767649 0,09292875 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04767649 0,09285006 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04767649 0,09277151 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04767649 0,09269309 ! arginine metabolic process GO:0006525 13 12 0,000 0,04767649 0,0926148 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04767649 0,09253665 ! methionine metabolic process GO:0006555 13 12 0,000 0,04767649 0,09245862 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04767649 0,09238073 ! Golgi organization GO:0007030 18 12 0,000 0,04767649 0,09230297 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04767649 0,09222534 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04767649 0,09214784 ! monoamine transport GO:0015844 13 12 0,000 0,04767649 0,09207047 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04767649 0,09199323 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04767649 0,09191611 ! L-amino acid transport GO:0015807 20 12 0,000 0,04767649 0,09183913 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04767649 0,09176228 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04767649 0,09168556 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04767649 0,09160896 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04767649 0,09153249 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04767649 0,09145615 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04767649 0,09137994 ! cerebellum development GO:0021549 13 12 0,000 0,04767649 0,09130385 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04767649 0,09122789 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04767649 0,09115206 ! histone acetylation GO:0016573 23 12 0,000 0,04767649 0,09107635 ! histone methylation GO:0016571 15 12 0,000 0,04767649 0,09100077 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04767649 0,09092531 ! gland morphogenesis GO:0022612 23 12 0,000 0,04767649 0,09084998 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04767649 0,09077477 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,04767649 0,09069969 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04767649 0,09062473 ! response to gamma radiation GO:0010332 20 12 0,000 0,04767649 0,0905499 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04767649 0,09047519 ! intestinal absorption GO:0050892 19 12 0,000 0,04767649 0,0904006 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04767649 0,09032613 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,04767649 0,09025179 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04767649 0,09017757 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,04767649 0,09010347 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04767649 0,09002949 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04767649 0,08995564 ! microspike assembly GO:0030035 23 12 0,000 0,04767649 0,08988191 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04767649 0,08980829 ! response to cold GO:0009409 14 12 0,000 0,04767649 0,0897348 ! cell cycle arrest GO:0007050 150 86 1,000 0,04776721 0,08983203 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,04876569 0,09163487 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 1,000 0,04876569 0,09156006 ! nucleosome organization GO:0034728 114 87 1,000 0,04876569 0,09148538 ! reproductive developmental process GO:0003006 127 89 1,000 0,05078538 0,09519672 ! regulation of T cell activation GO:0050863 128 89 1,000 0,05078538 0,09511919 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,05154684 0,09646682 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,05154684 0,09638839 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,05154684 0,09631009 ! cGMP metabolic process GO:0046068 16 13 0,000 0,05154684 0,09623192 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,05154684 0,09615387 ! water transport GO:0006833 17 13 0,000 0,05154684 0,09607595 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,05154684 0,09599816 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,05154684 0,09592049 ! lipid localization GO:0010876 24 13 0,000 0,05154684 0,09584295 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,05154684 0,09576553 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,05154684 0,09568824 ! organelle fusion GO:0048284 28 13 0,000 0,05154684 0,09561107 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,05154684 0,09553402 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,05154684 0,0954571 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,05154684 0,09538031 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,05154684 0,09530364 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,05154684 0,09522709 ! response to hexose stimulus GO:0009746 19 13 0,000 0,05154684 0,09515066 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,05154684 0,09507436 ! glutamate metabolic process GO:0006536 18 13 0,000 0,05154684 0,09499818 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,05154684 0,09492212 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,05154684 0,09484618 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,05154684 0,09477036 ! NAD metabolic process GO:0019674 21 13 0,000 0,05154684 0,09469467 ! exocrine system development GO:0035272 27 13 0,000 0,05154684 0,09461909 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,05154684 0,09454364 ! bone mineralization GO:0030282 15 13 0,000 0,05154684 0,09446831 ! regulation of exocytosis GO:0017157 17 13 0,000 0,05154684 0,09439309 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,05154684 0,094318 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,05154684 0,09424302 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,05154684 0,09416817 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,05154684 0,09409343 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,05154684 0,09401881 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,05154684 0,09394431 ! genitalia development GO:0048806 15 13 0,000 0,05154684 0,09386993 ! regulation of cellular pH GO:0030641 20 13 0,000 0,05154684 0,09379567 ! cellular pigmentation GO:0033059 24 13 0,000 0,05154684 0,09372152 ! tissue regeneration GO:0042246 21 13 0,000 0,05154684 0,09364749 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,05154684 0,09357358 ! cofactor transport GO:0051181 19 13 0,000 0,05154684 0,09349978 ! NADP metabolic process GO:0006739 18 13 0,000 0,05154684 0,0934261 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,05154684 0,09335254 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,05154684 0,09327909 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05154684 0,09320576 ! gas transport GO:0015669 18 13 0,000 0,05154684 0,09313254 ! regulation of RNA stability GO:0043487 28 13 0,000 0,05154684 0,09305944 ! heme biosynthetic process GO:0006783 20 13 0,000 0,05154684 0,09298645 ! regulation of axon extension GO:0030516 23 13 0,000 0,05154684 0,09291358 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,05154684 0,09284082 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,05154684 0,09276817 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,05154684 0,09269564 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,05154684 0,09262322 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,05154684 0,09255092 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,05154684 0,09247872 ! hormone metabolic process GO:0042445 121 90 1,000 0,05180644 0,09287203 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,05387062 0,09649721 ! cell fate commitment GO:0045165 141 92 1,000 0,05387062 0,09642212 ! DNA recombination GO:0006310 146 92 1,000 0,05387062 0,09634714 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,05491358 0,09813617 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05540167 0,09893156 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,05540167 0,09885481 ! superoxide anion generation GO:0042554 18 14 0,000 0,05540167 0,09877818 ! neuron maturation GO:0042551 21 14 0,000 0,05540167 0,09870167 ! regulation of S phase GO:0033261 18 14 0,000 0,05540167 0,09862527 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05540167 0,098549 ! myotube differentiation GO:0014902 21 14 0,000 0,05540167 0,09847284 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,05540167 0,0983968 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,05540167 0,09832087 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05540167 0,09824507 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05540167 0,09816938 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05540167 0,0980938 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05540167 0,09801835 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05540167 0,09794301 ! response to cAMP GO:0051591 19 14 0,000 0,05540167 0,09786778 ! limbic system development GO:0021761 25 14 0,000 0,05540167 0,09779267 ! startle response GO:0001964 21 14 0,000 0,05540167 0,09771768 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,05540167 0,0976428 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05540167 0,09756803 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05540167 0,09749338 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,05540167 0,09741885 ! glycine metabolic process GO:0006544 22 14 0,000 0,05540167 0,09734442 ! pituitary gland development GO:0021983 23 14 0,000 0,05540167 0,09727012 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,05540167 0,09719592 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,05540167 0,09712184 ! regulation of heart rate GO:0002027 23 14 0,000 0,05540167 0,09704787 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05540167 0,09697401 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,05540167 0,09690027 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05540167 0,09682664 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05540167 0,09675311 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,05540167 0,09667971 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,05540167 0,09660641 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,05540167 0,09653322 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,05540167 0,09646015 ! axon cargo transport GO:0008088 27 14 0,000 0,05540167 0,09638718 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05540167 0,09631433 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05540167 0,09624158 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,05540167 0,09616895 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05540167 0,09609642 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05540167 0,096024 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05540167 0,0959517 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05540167 0,0958795 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05540167 0,09580741 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05540167 0,09573543 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05540167 0,09566355 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,05540167 0,09559179 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,05540167 0,09552013 ! muscle maintenance GO:0046716 19 14 0,000 0,05540167 0,09544858 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05540167 0,09537713 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05540167 0,0953058 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05540167 0,09523457 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,05540167 0,09516344 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,05540167 0,09509243 ! cilium assembly GO:0042384 20 14 0,000 0,05540167 0,09502152 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05540167 0,09495071 ! regulation of binding GO:0051098 151 95 1,000 0,0570209 0,09765307 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05924107 0,1013798 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05924107 0,10130442 ! metencephalon development GO:0022037 19 15 0,000 0,05924107 0,10122916 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05924107 0,10115401 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05924107 0,10107897 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05924107 0,10100404 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05924107 0,10092922 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05924107 0,10085452 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05924107 0,10077992 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05924107 0,10070543 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05924107 0,10063106 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05924107 0,10055679 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05924107 0,10048263 ! adult walking behavior GO:0007628 25 15 0,000 0,05924107 0,10040859 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05924107 0,10033465 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05924107 0,10026082 ! myoblast differentiation GO:0045445 27 15 0,000 0,05924107 0,1001871 ! centrosome cycle GO:0007098 16 15 0,000 0,05924107 0,10011348 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05924107 0,10003998 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05924107 0,09996658 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05924107 0,09989329 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05924107 0,09982011 ! cerebral cortex development GO:0021987 29 15 0,000 0,05924107 0,09974704 ! response to osmotic stress GO:0006970 22 15 0,000 0,05924107 0,09967407 ! vesicle coating GO:0006901 25 15 0,000 0,05924107 0,09960121 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05924107 0,09952845 ! DNA integration GO:0015074 22 15 0,000 0,05924107 0,0994558 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05924107 0,09938326 ! peptide secretion GO:0002790 27 15 0,000 0,05924107 0,09931082 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05924107 0,09923849 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05924107 0,09916627 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05924107 0,09909415 ! neuron recognition GO:0008038 22 15 0,000 0,05924107 0,09902213 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05924107 0,09895022 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05924107 0,09887841 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05924107 0,09880671 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,05924107 0,09873511 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05924107 0,09866361 ! biomineral formation GO:0031214 18 15 0,000 0,05924107 0,09859222 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05924107 0,09852093 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05924107 0,09844975 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05924107 0,09837867 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05924107 0,09830768 ! organic cation transport GO:0015695 19 15 0,000 0,05924107 0,09823681 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05924107 0,09816603 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05924107 0,09809536 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05924107 0,09802479 ! defense response to virus GO:0051607 27 15 0,000 0,05924107 0,09795431 ! peptide hormone processing GO:0016486 19 15 0,000 0,05924107 0,09788394 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05924107 0,09781368 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,06131904 0,10117203 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,06241056 0,10289913 ! protein secretion GO:0009306 27 16 0,000 0,06306507 0,10390377 ! hormone secretion GO:0046879 25 16 0,000 0,06306507 0,10382939 ! bone remodeling GO:0046849 24 16 0,000 0,06306507 0,10375512 ! endothelial cell migration GO:0043542 22 16 0,000 0,06306507 0,10368096 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,06306507 0,1036069 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,06306507 0,10353295 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06306507 0,1034591 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,06306507 0,10338536 ! glial cell development GO:0021782 24 16 0,000 0,06306507 0,10331172 ! patterning of blood vessels GO:0001569 24 16 0,000 0,06306507 0,10323819 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,06306507 0,10316477 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,06306507 0,10309144 ! protein polyubiquitination GO:0000209 26 16 0,000 0,06306507 0,10301823 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,06306507 0,10294511 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,06306507 0,1028721 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,06306507 0,10279919 ! fructose metabolic process GO:0006000 20 16 0,000 0,06306507 0,10272639 ! regulation of protein binding GO:0043393 27 16 0,000 0,06306507 0,10265369 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,06306507 0,10258109 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,06306507 0,10250859 ! protein export from nucleus GO:0006611 24 16 0,000 0,06306507 0,1024362 ! negative regulation of immune response GO:0050777 28 16 0,000 0,06306507 0,10236391 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,06306507 0,10229172 ! DNA replication initiation GO:0006270 25 16 0,000 0,06306507 0,10221963 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,06306507 0,10214765 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,06306507 0,10207576 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,06306507 0,10200398 ! diencephalon development GO:0021536 25 16 0,000 0,06306507 0,1019323 ! oogenesis GO:0048477 23 16 0,000 0,06306507 0,10186072 ! neural crest cell migration GO:0001755 24 16 0,000 0,06306507 0,10178924 ! G1 phase GO:0051318 27 16 0,000 0,06306507 0,10171786 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,06306507 0,10164657 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,06306507 0,10157539 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,06306507 0,10150431 ! steroid catabolic process GO:0006706 22 16 0,000 0,06306507 0,10143333 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,06306507 0,10136245 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,06306507 0,10129166 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,06306507 0,10122098 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,06306507 0,10115039 ! sperm-egg recognition GO:0035036 16 16 0,000 0,06306507 0,1010799 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,06306507 0,10100951 ! nerve development GO:0021675 18 16 0,000 0,06306507 0,10093922 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,06306507 0,10086903 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,06306507 0,10079893 ! negative regulation of translation GO:0017148 22 16 0,000 0,06306507 0,10072893 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,06687375 0,10673811 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,06687375 0,10666409 ! negative regulation of defense response GO:0031348 19 17 0,000 0,06687375 0,10659017 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,06687375 0,10651636 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,06687375 0,10644265 ! glycerol metabolic process GO:0006071 20 17 0,000 0,06687375 0,10636903 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,06687375 0,10629552 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,06687375 0,10622211 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,06687375 0,10614881 ! signal complex assembly GO:0007172 29 17 0,000 0,06687375 0,1060756 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,06687375 0,1060025 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,06687375 0,10592949 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,06687375 0,10585659 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,06687375 0,10578378 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,06687375 0,10571108 ! memory GO:0007613 25 17 0,000 0,06687375 0,10563848 ! keratinization GO:0031424 17 17 0,000 0,06687375 0,10556597 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,06687375 0,10549357 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,06687375 0,10542126 ! retinoid metabolic process GO:0001523 22 17 0,000 0,06687375 0,10534906 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,06687375 0,10527695 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,06687375 0,10520494 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,06687375 0,10513303 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,06687375 0,10506122 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,06687375 0,1049895 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,06687375 0,10491789 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,06687375 0,10484637 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,06687375 0,10477495 ! membrane budding GO:0006900 29 17 0,000 0,06687375 0,10470362 ! heme metabolic process GO:0042168 27 17 0,000 0,06687375 0,1046324 ! actin filament bundle formation GO:0051017 26 17 0,000 0,06687375 0,10456127 ! body fluid secretion GO:0007589 27 17 0,000 0,06687375 0,10449023 ! stem cell differentiation GO:0048863 36 17 0,000 0,06687375 0,1044193 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,06687375 0,10434845 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,06687375 0,10427771 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,06687375 0,10420706 ! sensory perception of pain GO:0019233 23 17 0,000 0,06687375 0,10413651 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,06687375 0,10406605 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,06687375 0,10399569 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,06687375 0,10392542 ! synaptogenesis GO:0007416 24 17 0,000 0,06687375 0,10385525 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,06687375 0,10378517 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,06687375 0,10371519 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,06687375 0,1036453 ! cell-cell junction organization GO:0045216 25 17 0,000 0,06687375 0,1035755 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,06687375 0,1035058 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,06687375 0,1034362 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,06687375 0,10336668 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,06687375 0,10329726 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,06687375 0,10322793 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,06687375 0,1031587 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,07066716 0,10893731 ! positive regulation of translation GO:0045727 28 18 0,000 0,07066716 0,10886435 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,07066716 0,10879148 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,07066716 0,10871871 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,07066716 0,10864604 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,07066716 0,10857346 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,07066716 0,10850098 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,07066716 0,1084286 ! axis specification GO:0009798 26 18 0,000 0,07066716 0,10835632 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,07066716 0,10828413 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,07066716 0,10821203 ! pancreas development GO:0031016 26 18 0,000 0,07066716 0,10814004 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,07066716 0,10806813 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,07066716 0,10799633 ! glutamine metabolic process GO:0006541 23 18 0,000 0,07066716 0,10792462 ! response to retinoic acid GO:0032526 25 18 0,000 0,07066716 0,107853 ! pigmentation during development GO:0048066 31 18 0,000 0,07066716 0,10778148 ! central nervous system neuron development GO:0021954 30 18 0,000 0,07066716 0,10771005 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,07066716 0,10763872 ! fucose metabolic process GO:0006004 26 18 0,000 0,07066716 0,10756749 ! response to fungus GO:0009620 19 18 0,000 0,07066716 0,10749634 ! peptide cross-linking GO:0018149 31 18 0,000 0,07066716 0,1074253 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,07066716 0,10735434 ! heart process GO:0003015 27 18 0,000 0,07066716 0,10728348 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,07066716 0,10721271 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,07066716 0,10714204 ! visual learning GO:0008542 35 18 0,000 0,07066716 0,10707146 ! somitogenesis GO:0001756 24 18 0,000 0,07066716 0,10700097 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,07066716 0,10693057 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,07066716 0,10686027 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,07066716 0,10679006 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,07066716 0,10671994 ! vitamin transport GO:0051180 24 18 0,000 0,07066716 0,10664992 ! hormone transport GO:0009914 27 18 0,000 0,07066716 0,10657998 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,07066716 0,10651014 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,07066716 0,10644039 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,07066716 0,10637073 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,07066716 0,10630116 ! cell-cell recognition GO:0009988 20 18 0,000 0,07066716 0,10623168 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,07066716 0,10616229 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,07066716 0,106093 ! regulation of glucose import GO:0046324 21 18 0,000 0,07066716 0,10602379 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,07066716 0,10595468 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,07066716 0,10588565 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,07444537 0,11147419 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,07444537 0,11140166 ! positive regulation of ossification GO:0045778 30 19 0,000 0,07444537 0,11132923 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,07444537 0,11125689 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,07444537 0,11118464 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,07444537 0,11111249 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,07444537 0,11104044 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,07444537 0,11096847 ! regeneration GO:0031099 32 19 0,000 0,07444537 0,1108966 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,07444537 0,11082482 ! response to alkaloid GO:0043279 32 19 0,000 0,07444537 0,11075314 ! sensory perception of taste GO:0050909 23 19 0,000 0,07444537 0,11068155 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,07444537 0,11061005 ! smooth muscle contraction GO:0006939 36 19 0,000 0,07444537 0,11053864 ! peroxisome organization GO:0007031 29 19 0,000 0,07444537 0,11046732 ! digestive system process GO:0022600 30 19 0,000 0,07444537 0,1103961 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,07444537 0,11032497 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,07444537 0,11025393 ! response to vitamin A GO:0033189 26 19 0,000 0,07444537 0,11018298 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,07444537 0,11011212 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,07444537 0,11004136 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,07444537 0,10997068 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,07444537 0,1099001 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,07444537 0,1098296 ! plasma membrane fusion GO:0045026 23 19 0,000 0,07444537 0,1097592 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,07444537 0,10968889 ! cytolysis GO:0019835 20 19 0,000 0,07444537 0,10961866 ! renal system process GO:0003014 35 19 0,000 0,07444537 0,10954853 ! vasodilation GO:0042311 33 19 0,000 0,07444537 0,10947849 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,07444537 0,10940853 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,07444537 0,10933867 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,07444537 0,10926889 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,07444537 0,1091992 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,07444537 0,10912961 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,07444537 0,1090601 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,07444537 0,10899068 ! sarcomere organization GO:0045214 23 19 0,000 0,07444537 0,10892134 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,07444537 0,1088521 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,07444537 0,10878294 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,07444537 0,10871387 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,07444537 0,10864489 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,07444537 0,108576 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,07444537 0,10850719 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,07444537 0,10843848 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,07444537 0,10836984 ! protein stabilization GO:0050821 26 19 0,000 0,07444537 0,1083013 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,07820843 0,11370379 ! iron ion transport GO:0006826 37 20 0,000 0,07820843 0,11363196 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,07820843 0,11356023 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,07820843 0,11348858 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,07820843 0,11341702 ! response to vitamin GO:0033273 29 20 0,000 0,07820843 0,11334556 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,07820843 0,11327418 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,07820843 0,11320289 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,07820843 0,1131317 ! spinal cord development GO:0021510 31 20 0,000 0,07820843 0,11306059 ! response to ethanol GO:0045471 37 20 0,000 0,07820843 0,11298957 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,07820843 0,11291864 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,07820843 0,1128478 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,07820843 0,11277705 ! chromosome condensation GO:0030261 31 20 0,000 0,07820843 0,11270639 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,07820843 0,11263582 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,07820843 0,11256533 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,07820843 0,11249493 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,07820843 0,11242462 ! pallium development GO:0021543 38 20 0,000 0,07820843 0,1123544 ! DNA modification GO:0006304 28 20 0,000 0,07820843 0,11228427 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,07820843 0,11221422 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,07820843 0,11214426 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,07820843 0,11207439 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,07820843 0,11200461 ! collagen catabolic process GO:0030574 25 20 0,000 0,07820843 0,11193491 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,07820843 0,1118653 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,07820843 0,11179577 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,07820843 0,11172633 ! alditol metabolic process GO:0019400 24 20 0,000 0,07820843 0,11165698 ! actin filament-based movement GO:0030048 34 20 0,000 0,07820843 0,11158772 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,08195641 0,11686283 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,08195641 0,11679043 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,08195641 0,11671811 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,08195641 0,11664588 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,08195641 0,11657375 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,08195641 0,1165017 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,08195641 0,11642974 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,08195641 0,11635787 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,08195641 0,11628609 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,08195641 0,1162144 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,08195641 0,11614279 ! protein amino acid acylation GO:0043543 37 21 0,000 0,08195641 0,11607127 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,08195641 0,11599985 ! vesicle docking GO:0048278 27 21 0,000 0,08195641 0,1159285 ! phototransduction GO:0007602 25 21 0,000 0,08195641 0,11585725 ! dendrite development GO:0016358 35 21 0,000 0,08195641 0,11578609 ! visual behavior GO:0007632 39 21 0,000 0,08195641 0,11571501 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,08195641 0,11564402 ! ovarian follicle development GO:0001541 30 21 0,000 0,08195641 0,11557311 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,08195641 0,1155023 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,08195641 0,11543157 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,08195641 0,11536092 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,08195641 0,11529037 ! cell aging GO:0007569 32 21 0,000 0,08195641 0,1152199 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,08195641 0,11514951 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,08195641 0,11507921 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,08195641 0,115009 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,08195641 0,11493887 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,08195641 0,11486883 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,08195641 0,11479887 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,08195641 0,114729 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,08195641 0,11465921 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,08195641 0,11458951 ! fatty acid transport GO:0015908 30 21 0,000 0,08195641 0,1145199 ! immunoglobulin production GO:0002377 33 21 0,000 0,08195641 0,11445036 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,08195641 0,11438092 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,08195641 0,11431155 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,08195641 0,11424227 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,08195641 0,11417308 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,08195641 0,11410396 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,08195641 0,11403494 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,08195641 0,11396599 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,08195641 0,11389713 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,08195641 0,11382835 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,08195641 0,11375966 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,08195641 0,11369104 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,08195641 0,11362251 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,08195641 0,11355407 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,08195641 0,1134857 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,08568937 0,11858336 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,08568937 0,11851205 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,08568937 0,11844083 ! viral genome replication GO:0019079 29 22 0,000 0,08568937 0,11836969 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,08568937 0,11829864 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,08568937 0,11822768 ! leukocyte adhesion GO:0007159 38 22 0,000 0,08568937 0,1181568 ! molting cycle process GO:0022404 40 22 0,000 0,08568937 0,118086 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,08568937 0,11801529 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,08568937 0,11794467 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,08568937 0,11787413 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,08568937 0,11780367 ! vasculogenesis GO:0001570 33 22 0,000 0,08568937 0,1177333 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,08568937 0,11766301 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,08568937 0,1175928 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,08568937 0,11752268 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,08568937 0,11745265 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,08568937 0,11738269 ! lysosome organization GO:0007040 37 22 0,000 0,08568937 0,11731282 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,08568937 0,11724303 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,08568937 0,11717333 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,08568937 0,11710371 ! regulation of behavior GO:0050795 38 22 0,000 0,08568937 0,11703417 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,08568937 0,11696471 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,08568937 0,11689534 ! membrane depolarization GO:0051899 35 22 0,000 0,08568937 0,11682605 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,08568937 0,11675684 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,08568937 0,11668771 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,08568937 0,11661866 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,08568937 0,1165497 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,08568937 0,11648082 ! blastocyst development GO:0001824 37 22 0,000 0,08568937 0,11641201 ! neural tube closure GO:0001843 33 22 0,000 0,08568937 0,11634329 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,08568937 0,11627466 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,08940735 0,12124818 ! neuron fate commitment GO:0048663 32 23 0,000 0,08940735 0,12117673 ! embryonic pattern specification GO:0009880 31 23 0,000 0,08940735 0,12110537 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,08940735 0,12103409 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,08940735 0,12096289 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,08940735 0,12089178 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,08940735 0,12082075 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,08940735 0,1207498 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,08940735 0,12067894 ! vesicle targeting GO:0006903 32 23 0,000 0,08940735 0,12060816 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,08940735 0,12053746 ! osteoblast differentiation GO:0001649 40 23 0,000 0,08940735 0,12046685 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,08940735 0,12039632 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,08940735 0,12032587 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,08940735 0,1202555 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,08940735 0,12018522 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,08940735 0,12011502 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,08940735 0,1200449 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,08940735 0,11997486 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,08940735 0,1199049 ! cell fate determination GO:0001709 45 23 0,000 0,08940735 0,11983503 ! pentose metabolic process GO:0019321 31 23 0,000 0,08940735 0,11976524 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,08940735 0,11969552 ! spermatid development GO:0007286 33 23 0,000 0,08940735 0,11962589 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,08940735 0,11955634 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,08940735 0,11948687 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,08940735 0,11941749 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,08940735 0,11934818 ! telomere organization GO:0032200 32 23 0,000 0,08940735 0,11927895 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,08940735 0,1192098 ! regulation of amine transport GO:0051952 38 23 0,000 0,08940735 0,11914074 ! liver development GO:0001889 40 23 0,000 0,08940735 0,11907175 ! initiation of viral infection GO:0019059 42 24 0,000 0,09311043 0,12393171 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,09311043 0,12386003 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,09311043 0,12378844 ! superoxide metabolic process GO:0006801 32 24 0,000 0,09311043 0,12371692 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,09311043 0,12364549 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,09311043 0,12357415 ! fat cell differentiation GO:0045444 37 24 0,000 0,09311043 0,12350288 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,09311043 0,1234317 ! sperm motility GO:0030317 27 24 0,000 0,09311043 0,1233606 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,09311043 0,12328958 ! vacuole organization GO:0007033 39 24 0,000 0,09311043 0,12321864 ! receptor metabolic process GO:0043112 37 24 0,000 0,09311043 0,12314778 ! neural crest cell development GO:0014032 39 24 0,000 0,09311043 0,12307701 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,09311043 0,12300632 ! primary neural tube formation GO:0014020 35 24 0,000 0,09311043 0,1229357 ! negative regulation of cell development GO:0010721 56 24 0,000 0,09311043 0,12286517 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,09311043 0,12279472 ! base-excision repair GO:0006284 31 24 0,000 0,09311043 0,12272435 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,09311043 0,12265406 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,09311043 0,12258386 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,09311043 0,12251373 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,09311043 0,12244368 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,09679867 0,1272211 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,09679867 0,12714845 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,09679867 0,12707587 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,09679867 0,12700338 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,09679867 0,12693098 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,09679867 0,12685865 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,09679867 0,12678641 ! peptide transport GO:0015833 43 25 0,000 0,09679867 0,12671425 ! male gonad development GO:0008584 33 25 0,000 0,09679867 0,12664217 ! iron ion homeostasis GO:0055072 39 25 0,000 0,09679867 0,12657017 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,09679867 0,12649826 ! phospholipid transport GO:0015914 35 25 0,000 0,09679867 0,12642642 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,09679867 0,12635467 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,09679867 0,126283 ! detection of light stimulus GO:0009583 30 25 0,000 0,09679867 0,12621141 ! leukocyte proliferation GO:0070661 39 25 0,000 0,09679867 0,1261399 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,10047211 0,13085269 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,10047211 0,13077864 ! translational initiation GO:0006413 43 26 0,000 0,10047211 0,13070467 ! regulation of pH GO:0006885 36 26 0,000 0,10047211 0,13063078 ! circadian rhythm GO:0007623 42 26 0,000 0,10047211 0,13055698 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,10047211 0,13048326 ! post-embryonic development GO:0009791 42 26 0,000 0,10047211 0,13040962 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,10047211 0,13033607 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,10047211 0,1302626 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,10047211 0,13018921 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,10047211 0,13011591 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,10047211 0,13004268 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,10047211 0,12996954 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,10047211 0,12989649 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,10047211 0,12982351 ! regulation of coagulation GO:0050818 39 26 0,000 0,10047211 0,12975062 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,10413082 0,13440005 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,10413082 0,13432467 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,10413082 0,13424938 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,10413082 0,13417417 ! membrane docking GO:0022406 39 27 0,000 0,10413082 0,13409904 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,10413082 0,134024 ! catechol metabolic process GO:0009712 43 27 0,000 0,10413082 0,13394904 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,10413082 0,13387417 ! acute-phase response GO:0006953 42 27 0,000 0,10413082 0,13379938 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,10413082 0,13372467 ! myofibril assembly GO:0030239 36 27 0,000 0,10413082 0,13365005 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,10413082 0,13357551 ! response to ionizing radiation GO:0010212 47 27 0,000 0,10413082 0,13350105 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,10413082 0,13342668 ! natural killer cell activation GO:0030101 35 27 0,000 0,10413082 0,13335239 ! lipid oxidation GO:0034440 38 27 0,000 0,10413082 0,13327818 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,10413082 0,13320405 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,10413082 0,13313001 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,10413082 0,13305605 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,10413082 0,13298217 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,10413082 0,13290837 ! gene silencing GO:0016458 41 27 0,000 0,10413082 0,13283466 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,10777486 0,13740697 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,10777486 0,13733085 ! phenol metabolic process GO:0018958 44 28 0,000 0,10777486 0,13725481 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,10777486 0,13717885 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,10777486 0,13710297 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,10777486 0,13702719 ! cell junction assembly GO:0034329 56 28 0,000 0,10777486 0,13695148 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,10777486 0,13687586 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,10777486 0,13680032 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,10777486 0,13672486 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,10777486 0,13664949 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,10777486 0,1365742 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,10777486 0,136499 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,10777486 0,13642387 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,10777486 0,13634883 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,10777486 0,13627387 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,10777486 0,136199 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,10777486 0,13612421 ! mesoderm formation GO:0001707 46 28 0,000 0,10777486 0,13604949 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,10777486 0,13597486 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,10777486 0,13590032 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,10777486 0,13582585 ! BMP signaling pathway GO:0030509 40 28 0,000 0,10777486 0,13575147 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,10777486 0,13567716 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,10777486 0,13560294 ! neural tube formation GO:0001841 41 28 0,000 0,10777486 0,1355288 ! placenta development GO:0001890 37 28 0,000 0,10777486 0,13545474 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,11140429 0,13993984 ! regulation of innate immune response GO:0045088 38 29 0,000 0,11140429 0,13986346 ! ovulation cycle process GO:0022602 41 29 0,000 0,11140429 0,13978716 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,11140429 0,13971094 ! protein targeting to membrane GO:0006612 53 29 0,000 0,11140429 0,1396348 ! mismatch repair GO:0006298 34 29 0,000 0,11140429 0,13955875 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,11140429 0,13948277 ! muscle cell development GO:0055001 38 29 0,000 0,11140429 0,13940689 ! formation of primary germ layer GO:0001704 48 29 0,000 0,11140429 0,13933108 ! telencephalon development GO:0021537 52 29 0,000 0,11140429 0,13925536 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,11140429 0,13917972 ! eye morphogenesis GO:0048592 51 29 0,000 0,11140429 0,13910416 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,11140429 0,13902868 ! tissue homeostasis GO:0001894 42 29 0,000 0,11140429 0,13895328 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,11501915 0,14338431 ! collagen metabolic process GO:0032963 40 30 0,000 0,11501915 0,14330664 ! organic anion transport GO:0015711 51 30 0,000 0,11501915 0,14322905 ! cholesterol transport GO:0030301 46 30 0,000 0,11501915 0,14315154 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,11501915 0,14307412 ! spliceosome assembly GO:0000245 49 30 0,000 0,11501915 0,14299679 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,11501915 0,14291953 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,11501915 0,14284236 ! ceramide metabolic process GO:0006672 43 30 0,000 0,11501915 0,14276527 ! ovulation cycle GO:0042698 43 30 0,000 0,11501915 0,14268827 ! hindbrain development GO:0030902 45 30 0,000 0,11501915 0,14261135 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,11501915 0,14253451 ! adult locomotory behavior GO:0008344 47 30 0,000 0,11501915 0,14245776 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,11501915 0,14238108 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,11501915 0,14230449 ! response to heat GO:0009408 41 30 0,000 0,11501915 0,14222799 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,11501915 0,14215156 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,11501915 0,14207522 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,11861952 0,14644385 ! negative regulation of secretion GO:0051048 49 31 0,000 0,11861952 0,14636529 ! glial cell differentiation GO:0010001 55 31 0,000 0,11861952 0,14628681 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,11861952 0,14620841 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,11861952 0,1461301 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,11861952 0,14605187 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,11861952 0,14597373 ! segmentation GO:0035282 41 31 0,000 0,11861952 0,14589567 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,11861952 0,14581769 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,11861952 0,1457398 ! metanephros development GO:0001656 58 31 0,000 0,11861952 0,14566199 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,11861952 0,14558426 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,11861952 0,14550661 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,11861952 0,14542905 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,11861952 0,14535157 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,11861952 0,14527418 ! RNA modification GO:0009451 40 31 0,000 0,11861952 0,14519686 ! regulation of muscle development GO:0048634 48 32 0,000 0,12220545 0,14950667 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,12220545 0,14942718 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,12220545 0,14934779 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,12220545 0,14926847 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,12220545 0,14918924 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,12220545 0,1491101 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,12220545 0,14903104 ! regulation of protein stability GO:0031647 48 32 0,000 0,12220545 0,14895206 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,12220545 0,14887316 ! cytokine production GO:0001816 44 32 0,000 0,12220545 0,14879435 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,12220545 0,14871563 ! vesicle localization GO:0051648 47 32 0,000 0,12220545 0,14863698 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,12577699 0,15290015 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,12577699 0,15281938 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,12577699 0,15273869 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,12577699 0,15265809 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,12577699 0,15257757 ! ear morphogenesis GO:0042471 42 33 0,000 0,12577699 0,15249714 ! actomyosin structure organization GO:0031032 43 33 0,000 0,12577699 0,1524168 ! cell junction organization GO:0034330 63 33 0,000 0,12577699 0,15233654 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,12577699 0,15225636 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,12577699 0,15217627 ! nucleus organization GO:0006997 49 33 0,000 0,12577699 0,15209626 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,12577699 0,15201633 ! female gonad development GO:0008585 49 33 0,000 0,12577699 0,15193649 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,12577699 0,15185674 ! lipid homeostasis GO:0055088 55 33 0,000 0,12577699 0,15177706 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,12577699 0,15169747 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,12577699 0,15161797 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,12577699 0,15153854 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,12577699 0,1514592 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,12933421 0,15566126 ! mRNA catabolic process GO:0006402 48 34 0,000 0,12933421 0,15557985 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,12933421 0,15549852 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,12933421 0,15541728 ! feeding behavior GO:0007631 45 34 0,000 0,12933421 0,15533612 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,12933421 0,15525505 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,12933421 0,15517406 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,12933421 0,15509316 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,12933421 0,15501234 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,12933421 0,1549316 ! neuron migration GO:0001764 46 34 0,000 0,12933421 0,15485095 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,12933421 0,15477038 ! female gamete generation GO:0007292 43 34 0,000 0,12933421 0,1546899 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,12933421 0,1546095 ! aerobic respiration GO:0009060 47 34 0,000 0,12933421 0,15452918 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,12933421 0,15444895 ! embryonic organ development GO:0048568 45 34 0,000 0,12933421 0,1543688 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,13287715 0,15851527 ! Notch signaling pathway GO:0007219 56 35 0,000 0,13287715 0,1584331 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,13287715 0,15835101 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,13287715 0,158269 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,13287715 0,15818708 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,13287715 0,15810525 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,13287715 0,1580235 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,13287715 0,15794183 ! glycogen metabolic process GO:0005977 48 35 0,000 0,13287715 0,15786025 ! pigment metabolic process GO:0042440 61 35 0,000 0,13287715 0,15777875 ! protein homooligomerization GO:0051260 52 35 0,000 0,13287715 0,15769734 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,13640588 0,16180171 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,13640588 0,16171831 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,13640588 0,16163499 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,13640588 0,16155176 ! negative regulation of binding GO:0051100 58 36 0,000 0,13640588 0,16146861 ! organic ether metabolic process GO:0018904 46 36 0,000 0,13640588 0,16138555 ! tissue remodeling GO:0048771 62 36 0,000 0,13640588 0,16130258 ! neural tube development GO:0021915 50 36 0,000 0,13640588 0,16121969 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,13640588 0,16113689 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,13640588 0,16105417 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,13640588 0,16097153 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,13640588 0,16088898 ! glucan metabolic process GO:0044042 49 36 0,000 0,13640588 0,16080652 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,13992045 0,16486528 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,13992045 0,16478086 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,13992045 0,16469653 ! learning GO:0007612 67 37 0,000 0,13992045 0,16461229 ! ion transmembrane transport GO:0034220 56 37 0,000 0,13992045 0,16452813 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,13992045 0,16444406 ! regulation of protein secretion GO:0050708 51 37 0,000 0,13992045 0,16436008 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,13992045 0,16427618 ! gliogenesis GO:0042063 71 38 0,000 0,14342091 0,16830005 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,14342091 0,16821423 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,14342091 0,16812849 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,14342091 0,16804284 ! phagocytosis GO:0006909 60 38 0,000 0,14342091 0,16795728 ! mesenchymal cell development GO:0014031 64 38 0,000 0,14342091 0,16787181 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,14342091 0,16778642 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,14690733 0,17177777 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,14690733 0,17169048 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,14690733 0,17160329 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,14690733 0,17151618 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,14690733 0,17142916 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,14690733 0,17134223 ! male sex differentiation GO:0046661 53 39 0,000 0,14690733 0,17125538 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,14690733 0,17116863 ! chromatin remodeling GO:0006338 68 39 0,000 0,14690733 0,17108196 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,14690733 0,17099538 ! JNK cascade GO:0007254 54 39 0,000 0,14690733 0,17090889 ! developmental growth GO:0048589 62 39 0,000 0,14690733 0,17082248 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,15037976 0,17477183 ! response to calcium ion GO:0051592 58 40 0,000 0,15037976 0,17468356 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,15037976 0,17459538 ! regulation of tube size GO:0035150 60 40 0,000 0,15037976 0,17450729 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,15037976 0,17441929 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,15037976 0,17433138 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,15037976 0,17424355 ! peptide metabolic process GO:0006518 56 40 0,000 0,15037976 0,17415582 ! inner ear development GO:0048839 57 40 0,000 0,15037976 0,17406817 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,15037976 0,17398061 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,15037976 0,17389314 ! B cell differentiation GO:0030183 62 40 0,000 0,15037976 0,17380576 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,15037976 0,17371846 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,15037976 0,17363125 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,15037976 0,17354413 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,15037976 0,1734571 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,15383826 0,17735739 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,15383826 0,17726853 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,15383826 0,17717977 ! glucose transport GO:0015758 52 41 0,000 0,15383826 0,17709109 ! endosome transport GO:0016197 71 41 0,000 0,15383826 0,1770025 ! striated muscle contraction GO:0006941 62 41 0,000 0,15383826 0,176914 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,15383826 0,17682558 ! biopolymer methylation GO:0043414 62 41 0,000 0,15383826 0,17673726 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,15383826 0,17664902 ! mitochondrial transport GO:0006839 60 42 0,000 0,15728287 0,18051427 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,15728287 0,18042424 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,15728287 0,1803343 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,15728287 0,18024444 ! cellular component disassembly GO:0022411 64 42 0,000 0,15728287 0,18015468 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,15728287 0,18006501 ! hexose transport GO:0008645 54 42 0,000 0,15728287 0,17997542 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,15728287 0,17988593 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,15728287 0,17979652 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,15728287 0,1797072 ! excretion GO:0007588 63 42 0,000 0,15728287 0,17961797 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,15728287 0,17952883 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,15728287 0,17943978 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,15728287 0,17935082 ! regulation of cell shape GO:0008360 78 42 0,000 0,15728287 0,17926194 ! leukocyte migration GO:0050900 60 43 0,000 0,16071366 0,18308143 ! neuromuscular process GO:0050905 79 43 0,000 0,16071366 0,1829908 ! activation of caspase activity GO:0006919 65 43 0,000 0,16071366 0,18290025 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,16071366 0,1828098 ! tRNA processing GO:0008033 49 43 0,000 0,16071366 0,18271943 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,16071366 0,18262915 ! vesicle organization GO:0016050 79 43 0,000 0,16071366 0,18253897 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,16071366 0,18244887 ! methylation GO:0032259 64 43 0,000 0,16071366 0,18235886 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,16413067 0,18614425 ! glycolysis GO:0006096 53 44 0,000 0,16413067 0,18605251 ! regulation of ion transport GO:0043269 57 44 0,000 0,16413067 0,18596086 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,16413067 0,1858693 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,16413067 0,18577783 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,16413067 0,18568645 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,16413067 0,18559515 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,16413067 0,18550395 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,16413067 0,18541284 ! RNA catabolic process GO:0006401 64 45 0,000 0,16753397 0,18916452 ! positive regulation of defense response GO:0031349 59 45 0,000 0,16753397 0,1890717 ! regulation of translational initiation GO:0006446 64 45 0,000 0,16753397 0,18897898 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,16753397 0,18888634 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,16753397 0,18879379 ! cell recognition GO:0008037 58 45 0,000 0,16753397 0,18870134 ! cell maturation GO:0048469 60 45 0,000 0,16753397 0,18860897 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,17092361 0,19233087 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,17092361 0,19223682 ! cell redox homeostasis GO:0045454 63 46 0,000 0,17092361 0,19214286 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,17092361 0,192049 ! regulation of ossification GO:0030278 71 46 0,000 0,17092361 0,19195522 ! histone modification GO:0016570 68 46 0,000 0,17092361 0,19186154 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,17092361 0,19176795 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,17429963 0,19546034 ! viral infectious cycle GO:0019058 71 47 0,000 0,17429963 0,19536509 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,17429963 0,19526993 ! endocrine system development GO:0035270 83 47 0,000 0,17429963 0,19517486 ! covalent chromatin modification GO:0016569 75 47 0,000 0,17429963 0,19507988 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,17429963 0,194985 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,17429963 0,19489021 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,17429963 0,19479551 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,17429963 0,1947009 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,17429963 0,19460639 ! chloride transport GO:0006821 67 48 0,000 0,17766211 0,19826436 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,17766211 0,19816821 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,17766211 0,19807215 ! response to temperature stimulus GO:0009266 62 48 0,000 0,17766211 0,19797619 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,17766211 0,19788031 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,17766211 0,19778453 ! gastrulation GO:0007369 73 48 0,000 0,17766211 0,19768885 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,17766211 0,19759325 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,17766211 0,19749775 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,17766211 0,19740234 ! regulation of endocytosis GO:0030100 63 48 0,000 0,17766211 0,19730702 ! nuclear export GO:0051168 69 48 0,000 0,17766211 0,1972118 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,17766211 0,19711667 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,18101108 0,20073553 ! sensory perception of smell GO:0007608 61 49 0,000 0,18101108 0,20063879 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,18101108 0,20054214 ! RNA elongation GO:0006354 62 49 0,000 0,18101108 0,20044559 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,18101108 0,20034913 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,18101108 0,20025276 ! germ cell development GO:0007281 68 49 0,000 0,18101108 0,20015648 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,18101108 0,2000603 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,18101108 0,19996421 ! cartilage development GO:0051216 70 49 0,000 0,18101108 0,19986821 ! regulation of actin filament length GO:0030832 72 50 0,000 0,18434661 0,20345355 ! ear development GO:0043583 72 50 0,000 0,18434661 0,20335597 ! membrane fusion GO:0006944 80 50 0,000 0,18434661 0,20325848 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,18434661 0,20316109 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,18434661 0,20306379 ! proton transport GO:0015992 75 50 0,000 0,18434661 0,20296658 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,18434661 0,20286947 ! positive regulation of secretion GO:0051047 71 51 0,000 0,18766874 0,20642664 ! hydrogen transport GO:0006818 77 51 0,000 0,18766874 0,20632796 ! adult behavior GO:0030534 80 51 0,000 0,18766874 0,20622938 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,18766874 0,2061309 ! transition metal ion transport GO:0000041 74 52 0,000 0,19097753 0,20966507 ! regulation of cellular component size GO:0032535 74 52 0,000 0,19097753 0,20956503 ! aging GO:0007568 79 52 0,000 0,19097753 0,2094651 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,19097753 0,20936526 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,19097753 0,20926551 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,19427303 0,21277522 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,19427303 0,21267395 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,19427303 0,21257277 ! kidney development GO:0001822 90 53 0,000 0,19427303 0,21247169 ! single fertilization GO:0007338 59 53 0,000 0,19427303 0,21237071 ! cell projection assembly GO:0030031 76 53 0,000 0,19427303 0,21226982 ! amino acid transport GO:0006865 84 54 0,000 0,19755529 0,21575365 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,19755529 0,21565125 ! glucose catabolic process GO:0006007 66 54 0,000 0,19755529 0,21554895 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,19755529 0,21544674 ! DNA catabolic process GO:0006308 67 54 0,000 0,19755529 0,21534463 ! detection of external stimulus GO:0009581 66 54 0,000 0,19755529 0,21524262 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,19755529 0,21514071 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,19755529 0,21503889 ! mesoderm development GO:0007498 76 55 0,000 0,20082438 0,21849388 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,20082438 0,21839058 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,20082438 0,21828737 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,20408033 0,22172166 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,20408033 0,22161698 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,20408033 0,22151239 ! carbohydrate transport GO:0008643 74 57 0,000 0,2073232 0,22492611 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,2073232 0,22482007 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,2073232 0,22471412 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,2073232 0,22460827 ! camera-type eye development GO:0043010 88 57 0,000 0,2073232 0,22450253 ! secondary metabolic process GO:0019748 84 57 0,000 0,2073232 0,22439688 ! developmental maturation GO:0021700 75 57 0,000 0,2073232 0,22429133 ! gonad development GO:0008406 79 57 0,000 0,2073232 0,22418588 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,21055305 0,22757143 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,21055305 0,22746454 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,21055305 0,22735775 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,21376992 0,23072304 ! actin filament organization GO:0007015 95 59 0,000 0,21376992 0,23061483 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,21376992 0,23050671 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,21697386 0,23385187 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,21697386 0,23374233 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,21697386 0,2336329 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,21697386 0,23352358 ! regulation of heart contraction GO:0008016 91 60 0,000 0,21697386 0,23341435 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,21697386 0,23330523 ! fertilization GO:0009566 68 60 0,000 0,21697386 0,23319621 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,21697386 0,23308729 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,22016493 0,23640492 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,22016493 0,23629461 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,22016493 0,2361844 ! urogenital system development GO:0001655 101 61 0,000 0,22016493 0,23607429 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,22016493 0,23596428 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,22016493 0,23585438 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,22016493 0,23574457 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,22016493 0,23563488 ! amine catabolic process GO:0009310 90 62 0,000 0,22334318 0,23892527 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,22334318 0,23881419 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,22334318 0,23870322 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,22650866 0,24197395 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,22650866 0,24186162 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,22650866 0,24174938 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,22966142 0,24500059 ! appendage morphogenesis GO:0035107 93 64 0,000 0,22966142 0,244887 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,22966142 0,24477352 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,22966142 0,24466015 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,22966142 0,24454688 ! hexose catabolic process GO:0019320 82 64 0,000 0,22966142 0,24443372 ! adaptive immune response GO:0002250 94 64 0,000 0,22966142 0,24432066 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,23280151 0,24754668 ! regulation of caspase activity GO:0043281 97 65 0,000 0,23280151 0,24743228 ! appendage development GO:0048736 94 65 0,000 0,23280151 0,247318 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,23280151 0,24720382 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,23280151 0,24708974 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,23280151 0,24697577 ! defense response to bacterium GO:0042742 73 65 0,000 0,23280151 0,2468619 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,23280151 0,24674814 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,23280151 0,24663448 ! activation of immune response GO:0002253 83 65 0,000 0,23280151 0,24652093 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,23592897 0,24971774 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,23592897 0,24960287 ! antigen processing and presentation GO:0019882 96 66 0,000 0,23592897 0,24948811 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,23592897 0,24937346 ! regulation of immune effector process GO:0002697 101 66 0,000 0,23592897 0,24925891 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,23904387 0,25243384 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,23904387 0,25231799 ! acute inflammatory response GO:0002526 92 68 0,000 0,24214625 0,2554754 ! learning or memory GO:0007611 123 68 0,000 0,24214625 0,25535826 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,24214625 0,25524123 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,24214625 0,25512431 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,24214625 0,25500749 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,24214625 0,25489079 ! rhythmic process GO:0048511 105 68 0,000 0,24214625 0,25477418 ! inorganic anion transport GO:0015698 93 68 0,000 0,24214625 0,25465769 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,24523615 0,25778937 ! response to drug GO:0042493 108 69 0,000 0,24523615 0,25767161 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,24523615 0,25755395 ! response to metal ion GO:0010038 103 70 0,000 0,24831364 0,26066698 ! humoral immune response GO:0006959 86 70 0,000 0,24831364 0,26054807 ! eye development GO:0001654 111 70 0,000 0,24831364 0,26042926 ! amine transport GO:0015837 101 70 0,000 0,24831364 0,26031056 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,24831364 0,26019197 ! muscle cell differentiation GO:0042692 104 71 0,000 0,25137875 0,26328375 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,25137875 0,26316392 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,25137875 0,26304419 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,25137875 0,26292457 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,25137875 0,26280506 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,25443154 0,26587575 ! response to hypoxia GO:0001666 132 72 0,000 0,25443154 0,26575501 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,25443154 0,26563438 ! negative regulation of transport GO:0051051 116 73 0,000 0,25747205 0,26868681 ! tube morphogenesis GO:0035239 118 73 0,000 0,25747205 0,26856495 ! mitochondrion organization GO:0007005 104 73 0,000 0,25747205 0,26844321 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,25747205 0,26832158 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,25747205 0,26820005 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,26050034 0,27123168 ! response to oxygen levels GO:0070482 137 74 0,000 0,26050034 0,27110895 ! digestion GO:0007586 97 74 0,000 0,26050034 0,27098633 ! protein import into nucleus GO:0006606 118 74 0,000 0,26050034 0,27086383 ! blood coagulation GO:0007596 116 75 0,000 0,26351645 0,27387611 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,26351645 0,27375241 ! response to nutrient GO:0007584 104 75 0,000 0,26351645 0,27362882 ! regulation of ligase activity GO:0051340 114 75 0,000 0,26351645 0,27350534 ! nuclear import GO:0051170 121 75 0,000 0,26351645 0,27338198 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,26351645 0,27325872 ! amine biosynthetic process GO:0009309 97 76 0,000 0,26652044 0,27624921 ! response to unfolded protein GO:0006986 99 76 0,000 0,26652044 0,27612478 ! regulation of protein transport GO:0051223 114 76 0,000 0,26652044 0,27600045 GO:0070201|regulation of establishment of protein localization, ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,26951234 0,27897317 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,26951234 0,27884767 ! sex differentiation GO:0007548 105 77 0,000 0,26951234 0,27872229 ! protein ubiquitination GO:0016567 125 77 0,000 0,26951234 0,27859702 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,26951234 0,27847187 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,26951234 0,27834682 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,26951234 0,27822189 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,27249221 0,28117186 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,27249221 0,28104577 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,27249221 0,2809198 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,27546009 0,28385224 ! cellular respiration GO:0045333 107 79 0,000 0,27546009 0,28372513 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,27546009 0,28359812 ! T cell activation GO:0042110 134 79 0,000 0,27546009 0,28347124 ! regulation of lyase activity GO:0051339 133 79 0,000 0,27546009 0,28334446 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,27546009 0,2832178 ! alcohol catabolic process GO:0046164 104 80 0,000 0,27841604 0,28612908 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,27841604 0,28600129 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,27841604 0,28587361 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,27841604 0,28574605 ! forebrain development GO:0030900 131 80 0,000 0,27841604 0,28561859 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,28136009 0,28851013 ! hemostasis GO:0007599 125 81 0,000 0,28136009 0,28838156 ! mRNA transport GO:0051028 121 81 0,000 0,28136009 0,2882531 ! response to protein stimulus GO:0051789 111 81 0,000 0,28136009 0,28812476 ! regulation of neurological system process GO:0031644 122 81 0,000 0,28136009 0,28799654 ! vitamin metabolic process GO:0006766 103 81 0,000 0,28136009 0,28786842 ! detection of stimulus GO:0051606 108 82 0,000 0,28429231 0,29073913 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,28721272 0,29359523 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,28721272 0,2934648 ! regulation of defense response GO:0031347 117 84 0,000 0,29012139 0,29630515 ! sterol metabolic process GO:0016125 120 84 0,000 0,29012139 0,29617363 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,29301835 0,29899832 ! transcription initiation GO:0006352 118 85 0,000 0,29301835 0,29886573 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,29301835 0,29873325 ! regulation of protein localization GO:0032880 132 85 0,000 0,29301835 0,29860089 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,29590366 0,30140763 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,29877736 0,30420006 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,29877736 0,30406545 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,29877736 0,30393097 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,30163949 0,30670682 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,30163949 0,30657129 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,30163949 0,30643588 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,30163949 0,30630059 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,30163949 0,30616542 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,30449011 0,30892247 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,30449011 0,30878626 ! leukocyte differentiation GO:0002521 143 90 0,000 0,30732925 0,31152811 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,30732925 0,31139087 ! RNA localization GO:0006403 135 91 0,000 0,31015696 0,31411758 ! ATP metabolic process GO:0046034 137 91 0,000 0,31015696 0,31397932 ! response to virus GO:0009615 122 91 0,000 0,31015696 0,31384119 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,3129733 0,31655171 ! positive regulation of immune response GO:0050778 121 92 0,000 0,3129733 0,31641257 ! sulfur metabolic process GO:0006790 118 92 0,000 0,3129733 0,31627354 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,3157783 0,31896797 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,3157783 0,31882795 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,3157783 0,31868806 ! electron transport chain GO:0022900 123 94 0,000 0,318572 0,32136649 ! response to oxidative stress GO:0006979 141 94 0,000 0,318572 0,3212256 ! angiogenesis GO:0001525 149 95 0,000 0,32135446 0,32388924 ! carboxylic acid transport GO:0046942 147 95 0,000 0,32135446 0,32374737 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,32412572 0,3263963 ! in utero embryonic development GO:0001701 147 96 0,000 0,32412572 0,32625346 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,32412572 0,32611074 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,32412572 0,32596814 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,32412572 0,32582568 ! protein maturation GO:0051604 129 96 0,000 0,32412572 0,32568333 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,32688581 0,32831326 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,32688581 0,32816996 ! calcium ion transport GO:0006816 167 99 0,000 0,33237271 0,33353283 ! protein import GO:0017038 156 99 0,000 0,33237271 0,33338737 ! regulation of translation GO:0006417 151 100 0,000 0,33509961 0,33597606 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,33509961 0,33582967 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,33509961 0,3356834 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,33509961 0,33553726 ! divalent metal ion transport GO:0070838 171 100 0,000 0,33509961 0,33539125 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,33509961 0,33524536 ! protein localization in organelle GO:0033365 161 100 0,000 0,33509961 0,33509961