pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6909-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 9,397E-07 2,261E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,478E-06 1,778E-03 ! positive regulation of axonogenesis GO:0050772 28 15 2,000 1,183E-05 9,485E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,76E-05 0,01058514 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,931E-05 0,01410358 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,341E-05 0,01339883 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,942E-05 0,01354925 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 5,168E-05 0,01554279 ! negative regulation of kinase activity GO:0033673 131 68 3,000 5,478E-05 0,01464553 ! interaction with host GO:0051701 62 25 2,000 5,849E-05 0,01407242 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 6,597E-05 0,01443016 ! negative regulation of transferase activity GO:0051348 140 72 3,000 6,857E-05 0,01374871 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 7,406E-05 0,01370638 ! exocytosis GO:0006887 133 74 3,000 7,634E-05 0,01311966 ! positive regulation of glycolysis GO:0045821 14 5 1,000 8,976E-05 0,01439827 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 8,976E-05 0,01349838 ! meiotic chromosome segregation GO:0045132 7 5 1,000 8,976E-05 0,01270436 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 9,211E-05 0,01231222 ! regulation of neuron differentiation GO:0045664 167 81 3,000 1,086E-04 0,01375467 ! regulation of axonogenesis GO:0050770 75 32 2,000 1,242E-04 0,01494317 ! activation of MAPKKK activity GO:0000185 12 6 1,000 1,344E-04 0,01539634 ! male sex determination GO:0030238 15 6 1,000 1,344E-04 0,01469651 ! establishment of spindle localization GO:0051293 12 6 1,000 1,344E-04 0,01405753 GO:0051653|spindle localization, ! interaction with symbiont GO:0051702 13 6 1,000 1,344E-04 0,0134718 ! progesterone metabolic process GO:0042448 10 6 1,000 1,344E-04 0,01293293 ! positive regulation of neurogenesis GO:0050769 67 33 2,000 1,363E-04 0,01261661 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,492E-04 0,01329597 ! positive regulation of cell development GO:0010720 80 36 2,000 1,773E-04 0,01523119 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,854E-04 0,01538422 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,878E-04 0,01505872 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,925E-04 0,01493839 ! regulation of neuron projection development GO:0010975 91 38 2,000 2,085E-04 0,0156777 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 2,000 2,085E-04 0,01520261 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,499E-04 0,01768127 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,499E-04 0,01717609 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,017E-04 0,02016511 ! regulation of developmental growth GO:0048638 15 9 1,000 3,206E-04 0,02084874 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,206E-04 0,02030009 ! regulation of glycolysis GO:0006110 21 9 1,000 3,206E-04 0,01977957 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,206E-04 0,01928508 ! motor axon guidance GO:0008045 16 9 1,000 3,206E-04 0,01881472 ! protein heterooligomerization GO:0051291 16 9 1,000 3,206E-04 0,01836675 ! induction of an organ GO:0001759 14 9 1,000 3,206E-04 0,01793961 ! mitochondrion localization GO:0051646 15 9 1,000 3,206E-04 0,01753189 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,687E-04 0,01971368 ! response to insulin stimulus GO:0032868 95 46 2,000 3,687E-04 0,01928512 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4E-04 0,02047569 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4E-04 0,02004911 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4E-04 0,01963995 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 4E-04 0,01924715 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,183E-04 0,01973278 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,183E-04 0,0193533 ! regulation of cell projection organization GO:0031344 121 50 2,000 4,719E-04 0,02142386 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,879E-04 0,02173891 ! negative regulation of proteolysis GO:0045861 25 11 1,000 4,879E-04 0,02134366 ! developmental induction GO:0031128 19 11 1,000 4,879E-04 0,02096252 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 4,879E-04 0,02059476 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 5,003E-04 0,02075521 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to UV GO:0009411 104 53 2,000 5,604E-04 0,02285187 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 5,843E-04 0,02343186 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 5,843E-04 0,02304773 ! virus-host interaction GO:0019048 29 12 1,000 5,843E-04 0,02267599 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,843E-04 0,02231606 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 5,843E-04 0,02196737 GO:0042130|negative regulation of T cell proliferation, ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 6,892E-04 0,02551178 GO:0000725|recombinational repair, ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 6,892E-04 0,02512524 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 6,892E-04 0,02475023 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 6,939E-04 0,02455012 ! positive regulation of cell migration GO:0030335 126 57 2,000 6,939E-04 0,02419432 ! lipid modification GO:0030258 97 57 2,000 6,939E-04 0,02384869 ! cAMP biosynthetic process GO:0006171 23 14 1,000 8,025E-04 0,02719494 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 8,46E-04 0,0282717 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 1,000 9,242E-04 0,03045912 ! cell killing GO:0001906 29 15 1,000 9,242E-04 0,03004751 ! positive regulation of cell motion GO:0051272 146 64 2,000 9,73E-04 0,03121507 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,054E-03 0,03337064 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,054E-03 0,03293725 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,054E-03 0,03251498 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,192E-03 0,03631239 ! inositol metabolic process GO:0006020 28 17 1,000 1,192E-03 0,03585849 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,192E-03 0,03541579 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,339E-03 0,03927959 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 1,339E-03 0,03880634 ! epidermis morphogenesis GO:0048730 40 18 1,000 1,339E-03 0,03834436 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,339E-03 0,03789325 ! meiosis GO:0007126 121 74 2,000 1,481E-03 0,04144288 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 2,000 1,481E-03 0,04096653 ! skin development GO:0043588 36 19 1,000 1,493E-03 0,04082718 ! lipid phosphorylation GO:0046834 35 19 1,000 1,493E-03 0,04036845 ! neuromuscular junction development GO:0007528 34 19 1,000 1,493E-03 0,03991991 ! meiotic cell cycle GO:0051321 122 75 2,000 1,54E-03 0,04070908 ! regulation of catabolic process GO:0009894 161 76 2,000 1,599E-03 0,04183031 ! cAMP metabolic process GO:0046058 36 20 1,000 1,656E-03 0,04284038 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,656E-03 0,04238463 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 1,000 1,656E-03 0,04193848 ! cellular response to starvation GO:0009267 33 20 1,000 1,656E-03 0,04150162 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,656E-03 0,04107377 ! regulation of vasoconstriction GO:0019229 39 21 1,000 1,827E-03 0,04484591 ! collagen fibril organization GO:0030199 59 21 1,000 1,827E-03 0,04439292 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 1,989E-03 0,04785168 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,005E-03 0,04777133 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 2,005E-03 0,04730299 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,192E-03 0,05120441 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,192E-03 0,05071206 ! sex determination GO:0007530 47 23 1,000 2,192E-03 0,05022909 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,192E-03 0,04975523 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,387E-03 0,05366571 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,387E-03 0,05316881 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,387E-03 0,05268102 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,387E-03 0,0522021 ! protein tetramerization GO:0051262 52 24 1,000 2,387E-03 0,05173181 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 2,512E-03 0,05396097 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,589E-03 0,05512671 ! myelination GO:0042552 45 25 1,000 2,589E-03 0,05464315 ! response to starvation GO:0042594 42 25 1,000 2,589E-03 0,05416799 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,589E-03 0,05370102 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,799E-03 0,05756582 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,799E-03 0,05707797 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 2,799E-03 0,05659833 GO:0045840|positive regulation of mitosis, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,017E-03 0,06049802 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,017E-03 0,05999804 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 3,017E-03 0,05950625 ! regulation of chromosome organization GO:0033044 42 27 1,000 3,017E-03 0,05902246 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,017E-03 0,05854647 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 3,022E-03 0,05816688 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,243E-03 0,06192768 ! lipid oxidation GO:0034440 43 28 1,000 3,243E-03 0,06144006 GO:0019395|fatty acid oxidation, ! interphase GO:0051325 213 98 2,000 3,299E-03 0,06201329 ! ensheathment of neurons GO:0007272 57 30 1,000 3,718E-03 0,06933624 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,718E-03 0,06880288 ! neurotransmitter secretion GO:0007269 48 30 1,000 3,718E-03 0,06827767 ! regulation of B cell activation GO:0050864 50 30 1,000 3,718E-03 0,06776041 ! fatty acid catabolic process GO:0009062 48 31 1,000 3,966E-03 0,07174818 ! peripheral nervous system development GO:0007422 64 32 1,000 4,222E-03 0,07581158 ! positive regulation of catabolic process GO:0009896 64 32 1,000 4,222E-03 0,07525001 ! spindle organization GO:0007051 46 32 1,000 4,222E-03 0,0746967 ! cell fate specification GO:0001708 52 33 1,000 4,486E-03 0,07878096 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 5,035E-03 0,08778996 ! odontogenesis GO:0042476 66 35 1,000 5,035E-03 0,08715838 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,035E-03 0,08653582 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 5,321E-03 0,09079841 ! regulation of proteolysis GO:0030162 72 36 1,000 5,321E-03 0,09015899 ! hormone biosynthetic process GO:0042446 57 36 1,000 5,321E-03 0,0895285 ! negative regulation of cell activation GO:0050866 65 36 1,000 5,321E-03 0,08890678 ! meiosis I GO:0007127 65 37 1,000 5,614E-03 0,09315648 ! sister chromatid segregation GO:0000819 58 37 1,000 5,614E-03 0,09251842 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 5,614E-03 0,09188905 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 5,914E-03 0,09615031 ! carbohydrate homeostasis GO:0033500 53 38 1,000 5,914E-03 0,095505 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,914E-03 0,0948683 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 6,222E-03 0,09913996 ! regulation of action potential in neuron GO:0019228 73 39 1,000 6,222E-03 0,09848772 ! Rho protein signal transduction GO:0007266 74 39 1,000 6,222E-03 0,09784401 ! cytokinesis GO:0000910 72 40 1,000 6,537E-03 0,10212498 ! regulation of T cell proliferation GO:0042129 71 41 1,000 6,858E-03 0,10646112 ! regulation of T cell differentiation GO:0045580 70 41 1,000 6,858E-03 0,10577868 ! polyol metabolic process GO:0019751 66 41 1,000 6,858E-03 0,10510493 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 7,523E-03 0,1145623 ! double-strand break repair GO:0006302 81 44 1,000 7,866E-03 0,11903001 ! maintenance of location in cell GO:0051651 97 44 1,000 7,866E-03 0,11828607 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 8,216E-03 0,12277879 ! cell growth GO:0016049 84 45 1,000 8,216E-03 0,1220209 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 8,573E-03 0,1265373 ! positive regulation of DNA binding GO:0043388 73 47 1,000 8,936E-03 0,13109908 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 9,306E-03 0,13570477 ! regulation of action potential GO:0001508 95 49 1,000 9,684E-03 0,14035295 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01006735 0,14504223 ! positive regulation of binding GO:0051099 78 51 1,000 0,01045784 0,14977127 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01085497 0,15453874 ! positive regulation of growth GO:0045927 90 52 1,000 0,01085497 0,15362969 ! amino acid activation GO:0043038 92 52 1,000 0,01085497 0,15273127 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,01085497 0,1518433 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,01125868 0,15658019 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01166893 0,16135314 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,01166893 0,16043112 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01208569 0,16521685 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01208569 0,16428343 ! heart morphogenesis GO:0003007 97 55 1,000 0,01208569 0,16336049 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01250891 0,16813649 ! regulation of DNA replication GO:0006275 101 56 1,000 0,01250891 0,1672024 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01250891 0,16627863 ! muscle fiber development GO:0048747 112 57 1,000 0,01293855 0,17104474 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01293855 0,17011006 ! maintenance of location GO:0051235 118 57 1,000 0,01293855 0,16918555 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01337456 0,1739416 ! establishment of organelle localization GO:0051656 109 59 1,000 0,01381691 0,17872846 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,01426556 0,18354511 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01501772 0,19219481 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01501772 0,1911779 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01501772 0,1901717 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01501772 0,18917604 ! neuron fate determination GO:0048664 7 5 0,000 0,01501772 0,18819075 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01501772 0,18721567 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01501772 0,18625064 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01501772 0,18529551 ! polyol transport GO:0015791 12 5 0,000 0,01501772 0,18435012 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01501772 0,18341433 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01501772 0,182488 ! response to superoxide GO:0000303 10 5 0,000 0,01501772 0,18157097 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01501772 0,18066312 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01501772 0,1797643 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01501772 0,17887437 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01501772 0,17799322 ! female meiosis GO:0007143 7 5 0,000 0,01501772 0,1771207 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01501772 0,1762567 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01501772 0,17540109 ! cobalt ion transport GO:0006824 11 5 0,000 0,01501772 0,17455374 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01501772 0,17371454 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01501772 0,17288337 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01501772 0,17206011 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01501772 0,17124466 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01501772 0,1704369 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01501772 0,16963673 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01501772 0,16884404 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01501772 0,16805871 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01501772 0,16728067 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01501772 0,16650979 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01501772 0,16574598 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01501772 0,16498915 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01501772 0,1642392 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01501772 0,16349603 ! negative chemotaxis GO:0050919 14 5 0,000 0,01501772 0,16275957 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01501772 0,1620297 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01501772 0,16130636 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01501772 0,16058944 ! behavioral response to pain GO:0048266 9 5 0,000 0,01501772 0,15987887 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01501772 0,15917455 ! Notch receptor processing GO:0007220 8 5 0,000 0,01501772 0,15847642 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01501772 0,15778438 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01501772 0,15709836 ! micturition GO:0060073 9 5 0,000 0,01501772 0,15641828 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01501772 0,15574407 ! copulation GO:0007620 9 5 0,000 0,01501772 0,15507564 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01501772 0,15441292 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01501772 0,15375585 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01501772 0,15310434 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01501772 0,15245833 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01501772 0,15181775 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01501772 0,15118253 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01501772 0,1505526 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01501772 0,1499279 ! grooming behavior GO:0007625 6 5 0,000 0,01501772 0,14930836 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01501772 0,14869392 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01501772 0,14808452 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01501772 0,1474801 ! response to protozoan GO:0001562 10 5 0,000 0,01501772 0,14688058 ! lymph vessel development GO:0001945 10 5 0,000 0,01501772 0,14628593 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01501772 0,14569606 ! endochondral ossification GO:0001958 16 5 0,000 0,01501772 0,14511094 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01501772 0,14453049 ! parathyroid gland development GO:0060017 13 5 0,000 0,01501772 0,14395468 ! anagen GO:0042640 6 5 0,000 0,01501772 0,14338343 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01501772 0,14281669 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01501772 0,14225442 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01501772 0,14169656 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01501772 0,14114306 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01501772 0,14059387 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01501772 0,14004893 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01501772 0,1395082 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01501772 0,13897163 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01501772 0,13843917 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01501772 0,13791078 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01501772 0,1373864 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01501772 0,136866 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01501772 0,13634952 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01501772 0,13583693 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01501772 0,13532818 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01501772 0,13482322 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01501772 0,13432202 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01501772 0,13382453 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01501772 0,13333071 ! histidine catabolic process GO:0006548 6 5 0,000 0,01501772 0,13284053 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01501772 0,13235393 ! microvillus organization GO:0032528 7 5 0,000 0,01501772 0,13187089 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01501772 0,13139136 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01501772 0,1309153 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01501772 0,13044268 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01501772 0,12997347 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01501772 0,12950761 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01501772 0,12904508 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01501772 0,12858585 ! polyol catabolic process GO:0046174 7 5 0,000 0,01501772 0,12812987 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01501772 0,12767712 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01501772 0,12722755 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01501772 0,12678114 ! muscle cell migration GO:0014812 8 5 0,000 0,01501772 0,12633785 ! mitochondrial fission GO:0000266 8 5 0,000 0,01501772 0,12589764 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01501772 0,1254605 ! mRNA transcription GO:0009299 9 5 0,000 0,01501772 0,12502638 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01501772 0,12459525 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01501772 0,12416709 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01501772 0,12374186 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01501772 0,12331953 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01501772 0,12290008 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01501772 0,12248347 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01501772 0,12206967 ! response to food GO:0032094 6 5 0,000 0,01501772 0,12165867 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01501772 0,12125042 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01501772 0,1208449 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01501772 0,12044208 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01501772 0,12004194 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01501772 0,11964445 ! forebrain neuron development GO:0021884 13 5 0,000 0,01501772 0,11924958 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01501772 0,11885731 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01501772 0,11846762 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01501772 0,11808047 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01501772 0,11769584 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01501772 0,11731371 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01501772 0,11693406 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01501772 0,11655685 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01501772 0,11618207 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01501772 0,11580969 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01501772 0,11543969 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01501772 0,11507205 ! basic amino acid transport GO:0015802 11 5 0,000 0,01501772 0,11470674 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01501772 0,11434375 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01501772 0,11398304 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01501772 0,1136246 ! depyrimidination GO:0045008 10 5 0,000 0,01501772 0,11326841 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01501772 0,11291445 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01501772 0,11256269 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01501772 0,11221312 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01501772 0,11186571 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01501772 0,11152044 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01501772 0,1111773 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01501772 0,11083627 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01501772 0,11049732 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01501772 0,11016044 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01501772 0,1098256 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01501772 0,1094928 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01501772 0,10916201 ! response to arsenic GO:0046685 10 5 0,000 0,01501772 0,1088332 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01501772 0,10850638 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01501772 0,10818151 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01501772 0,10785858 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01501772 0,10753757 ! response to cadmium ion GO:0046686 7 5 0,000 0,01501772 0,10721847 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01501772 0,10690125 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01501772 0,10658591 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01501772 0,10627242 ! decidualization GO:0046697 11 5 0,000 0,01501772 0,10596077 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01501772 0,10565095 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01501772 0,10534293 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01501772 0,1050367 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01501772 0,10473224 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01501772 0,10442955 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01501772 0,1041286 ! neural tube patterning GO:0021532 7 5 0,000 0,01501772 0,10382938 ! embryonic cleavage GO:0040016 6 5 0,000 0,01501772 0,10353187 ! peroxisome fission GO:0016559 5 5 0,000 0,01501772 0,10323607 ! histone demethylation GO:0016577 10 5 0,000 0,01501772 0,10294195 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01501772 0,1026495 ! mitotic recombination GO:0006312 9 5 0,000 0,01501772 0,10235871 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01501772 0,10206956 ! metaphase plate congression GO:0051310 7 5 0,000 0,01501772 0,10178204 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01501772 0,10149613 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01501772 0,10121183 ! enteric nervous system development GO:0048484 8 5 0,000 0,01501772 0,10092912 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01501772 0,10064798 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01501772 0,1003684 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01501772 0,10009037 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01501772 0,09981388 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01501772 0,09953891 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01501772 0,09926545 ! plasminogen activation GO:0031639 5 5 0,000 0,01501772 0,09899349 ! B cell homeostasis GO:0001782 13 5 0,000 0,01501772 0,09872302 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01501772 0,09845402 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01501772 0,09818648 ! metaphase GO:0051323 8 5 0,000 0,01501772 0,09792039 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01501772 0,09765574 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01501772 0,09739252 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01501772 0,09713071 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01501772 0,0968703 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01501772 0,09661129 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01501772 0,09635366 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01501772 0,0960974 ! response to redox state GO:0051775 5 5 0,000 0,01501772 0,0958425 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01501772 0,09558895 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01501772 0,09533674 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01501772 0,09508585 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01501772 0,09483628 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01501772 0,09458802 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01501772 0,09434105 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01501772 0,09409537 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01501772 0,09385097 ! striatum development GO:0021756 9 5 0,000 0,01501772 0,09360783 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01501772 0,09336595 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01501772 0,09312532 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01501772 0,09288592 ! glial cell migration GO:0008347 11 5 0,000 0,01501772 0,09264775 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01501772 0,0924108 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01501772 0,09217506 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01501772 0,09194052 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01501772 0,09170717 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01501772 0,091475 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01501772 0,091244 ! neuroprotection GO:0043526 6 5 0,000 0,01501772 0,09101417 ! neural plate development GO:0001840 8 5 0,000 0,01501772 0,09078549 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01501772 0,09055795 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01501772 0,09033156 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01501772 0,09010629 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01501772 0,08988215 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01501772 0,08965912 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01501772 0,08943719 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01501772 0,08921635 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01501772 0,08899661 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01501772 0,08877795 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01501772 0,08856035 ! spindle assembly GO:0051225 6 5 0,000 0,01501772 0,08834382 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01501772 0,08812835 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01501772 0,08791393 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01501772 0,08770054 ! drug metabolic process GO:0017144 6 5 0,000 0,01501772 0,08748819 ! stem cell division GO:0017145 11 5 0,000 0,01501772 0,08727687 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01501772 0,08706656 ! organ regeneration GO:0031100 7 5 0,000 0,01501772 0,08685727 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01501772 0,08664898 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01501772 0,08644168 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01501772 0,08623538 ! viral reproductive process GO:0022415 126 62 1,000 0,01518157 0,08696871 ! regulation of mitosis GO:0007088 105 63 1,000 0,01564885 0,08943263 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,01564885 0,08922071 ! extracellular matrix organization GO:0030198 133 66 1,000 0,01708732 0,09719172 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,01757889 0,09975189 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01757889 0,09951718 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01757889 0,09928357 ! lung development GO:0030324 144 67 1,000 0,01757889 0,09905105 ! chromosome segregation GO:0007059 113 67 1,000 0,01757889 0,09881963 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01757889 0,09858928 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01799438 0,10068485 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01799438 0,10045124 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01799438 0,10021871 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01799438 0,09998726 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01799438 0,09975688 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01799438 0,09952755 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01799438 0,09929927 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01799438 0,09907205 ! sleep GO:0030431 13 6 0,000 0,01799438 0,09884585 ! response to oxygen radical GO:0000305 11 6 0,000 0,01799438 0,09862069 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01799438 0,09839655 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01799438 0,09817343 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01799438 0,09795132 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01799438 0,09773021 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01799438 0,0975101 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01799438 0,09729097 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01799438 0,09707283 ! forebrain regionalization GO:0021871 8 6 0,000 0,01799438 0,09685567 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01799438 0,09663947 ! male meiosis GO:0007140 7 6 0,000 0,01799438 0,09642424 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01799438 0,09620996 ! response to zinc ion GO:0010043 9 6 0,000 0,01799438 0,09599664 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01799438 0,09578426 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01799438 0,09557281 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01799438 0,0953623 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01799438 0,09515271 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01799438 0,09494404 ! malate metabolic process GO:0006108 11 6 0,000 0,01799438 0,09473629 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01799438 0,09452944 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01799438 0,09432349 ! protein refolding GO:0042026 15 6 0,000 0,01799438 0,09411844 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01799438 0,09391428 ! opsonization GO:0008228 8 6 0,000 0,01799438 0,093711 ! mating behavior GO:0007617 7 6 0,000 0,01799438 0,0935086 ! neuron remodeling GO:0016322 15 6 0,000 0,01799438 0,09330708 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01799438 0,09310642 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01799438 0,09290662 ! equilibrioception GO:0050957 14 6 0,000 0,01799438 0,09270767 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01799438 0,09250958 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01799438 0,09231233 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01799438 0,09211592 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01799438 0,09192035 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01799438 0,0917256 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01799438 0,09153168 ! toxin metabolic process GO:0009404 11 6 0,000 0,01799438 0,09133857 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01799438 0,09114628 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01799438 0,0909548 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01799438 0,09076412 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01799438 0,09057423 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01799438 0,09038514 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01799438 0,09019684 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01799438 0,09000932 ! thymic T cell selection GO:0045061 12 6 0,000 0,01799438 0,08982258 ! protein lipoylation GO:0009249 10 6 0,000 0,01799438 0,08963661 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01799438 0,08945141 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01799438 0,08926698 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01799438 0,0890833 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01799438 0,08890038 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01799438 0,0887182 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01799438 0,08853678 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01799438 0,08835609 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01799438 0,08817614 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01799438 0,08799692 ! hyperosmotic response GO:0006972 9 6 0,000 0,01799438 0,08781843 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01799438 0,08764066 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01799438 0,0874636 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01799438 0,08728727 ! urea metabolic process GO:0019627 7 6 0,000 0,01799438 0,08711164 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01799438 0,08693671 ! neutrophil activation GO:0042119 8 6 0,000 0,01799438 0,08676249 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01799438 0,08658897 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01799438 0,08641614 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01799438 0,08624399 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01799438 0,08607253 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01799438 0,08590175 ! neuron apoptosis GO:0051402 9 6 0,000 0,01799438 0,08573165 ! nucleoside salvage GO:0043174 9 6 0,000 0,01799438 0,08556222 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01799438 0,08539346 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01799438 0,08522536 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01799438 0,08505792 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01799438 0,08489114 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01799438 0,08472502 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01799438 0,08455954 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01799438 0,08439471 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01799438 0,08423051 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01799438 0,08406696 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01799438 0,08390404 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01799438 0,08374175 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01799438 0,08358008 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01799438 0,08341904 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01799438 0,08325862 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01799438 0,08309882 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01799438 0,08293962 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01799438 0,08278104 ! neural nucleus development GO:0048857 14 6 0,000 0,01799438 0,08262306 ! response to UV-C GO:0010225 11 6 0,000 0,01799438 0,08246568 ! astrocyte development GO:0014002 15 6 0,000 0,01799438 0,0823089 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01799438 0,08215272 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01799438 0,08199713 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01799438 0,08184212 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01799438 0,08168771 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01799438 0,08153387 ! response to copper ion GO:0046688 10 6 0,000 0,01799438 0,08138061 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01799438 0,08122792 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01799438 0,08107581 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01799438 0,08092427 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01799438 0,08077329 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01799438 0,08062287 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01799438 0,08047302 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01799438 0,08032372 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01799438 0,08017497 ! hair follicle maturation GO:0048820 7 6 0,000 0,01799438 0,08002677 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01799438 0,07987912 ! Schwann cell development GO:0014044 15 6 0,000 0,01799438 0,07973201 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01799438 0,07958545 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01799438 0,07943942 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01799438 0,07929393 ! subpallium development GO:0021544 10 6 0,000 0,01799438 0,07914896 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01799438 0,07900453 ! histone ubiquitination GO:0016574 8 6 0,000 0,01799438 0,07886063 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01799438 0,07871724 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01799438 0,07857438 ! G2 phase GO:0051319 16 6 0,000 0,01799438 0,07843204 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01799438 0,07829021 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01799438 0,07814889 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01799438 0,07800808 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01799438 0,07786778 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01799438 0,07772798 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01799438 0,07758868 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01799438 0,07744988 ! receptor internalization GO:0031623 10 6 0,000 0,01799438 0,07731158 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01799438 0,07717377 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01799438 0,07703645 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01799438 0,07689962 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01799438 0,07676327 ! protein deubiquitination GO:0016579 14 6 0,000 0,01799438 0,0766274 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01799438 0,07649202 ! protein destabilization GO:0031648 9 6 0,000 0,01799438 0,07635711 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01799438 0,07622268 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01799438 0,07608872 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01799438 0,07595523 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01799438 0,07582221 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01799438 0,07568966 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01799438 0,07555756 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01799438 0,07542593 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01799438 0,07529475 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01799438 0,07516403 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01799438 0,07503377 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01799438 0,07490395 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01799438 0,07477458 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01799438 0,07464566 ! catecholamine transport GO:0051937 9 6 0,000 0,01799438 0,07451718 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01799438 0,07438915 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01799438 0,07426155 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01799438 0,07413439 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01799438 0,07400766 ! maternal placenta development GO:0001893 12 6 0,000 0,01799438 0,07388137 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01799438 0,07375551 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01799438 0,07363007 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01799438 0,07350507 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01799438 0,07338048 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01799438 0,07325632 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01799438 0,07313257 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01799438 0,07300925 ! viral reproduction GO:0016032 134 68 1,000 0,01807642 0,07321863 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01807642 0,07309557 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01857988 0,07500537 ! respiratory tube development GO:0030323 150 70 1,000 0,01908924 0,07693251 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02012546 0,08097301 ! respiratory system development GO:0060541 153 72 1,000 0,02012546 0,08083783 ! regulation of blood pressure GO:0008217 125 73 1,000 0,02065225 0,08281554 ! axon guidance GO:0007411 139 73 1,000 0,02065225 0,08267774 ! tRNA transcription GO:0009304 14 7 0,000 0,02096215 0,08377897 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02096215 0,08364003 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02096215 0,08350155 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02096215 0,08336353 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02096215 0,08322597 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02096215 0,08308886 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02096215 0,0829522 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02096215 0,08281599 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02096215 0,08268023 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02096215 0,08254491 ! prostate gland development GO:0030850 13 7 0,000 0,02096215 0,08241003 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02096215 0,08227559 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02096215 0,08214159 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02096215 0,08200803 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02096215 0,0818749 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02096215 0,0817422 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02096215 0,08160993 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02096215 0,08147809 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02096215 0,08134667 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02096215 0,08121568 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02096215 0,08108511 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02096215 0,08095496 ! glycolipid transport GO:0046836 10 7 0,000 0,02096215 0,08082522 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02096215 0,0806959 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02096215 0,08056699 ! neuron adhesion GO:0007158 12 7 0,000 0,02096215 0,0804385 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02096215 0,08031041 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02096215 0,08018273 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02096215 0,08005546 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02096215 0,07992859 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02096215 0,07980212 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02096215 0,07967605 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02096215 0,07955037 ! mRNA stabilization GO:0048255 18 7 0,000 0,02096215 0,0794251 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02096215 0,07930022 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02096215 0,07917573 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02096215 0,07905163 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02096215 0,07892791 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02096215 0,07880459 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02096215 0,07868165 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02096215 0,07855909 ! lipoprotein transport GO:0042953 14 7 0,000 0,02096215 0,07843692 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02096215 0,07831512 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02096215 0,0781937 ! rhythmic behavior GO:0007622 15 7 0,000 0,02096215 0,07807266 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02096215 0,07795199 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02096215 0,07783169 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02096215 0,07771177 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02096215 0,07759221 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02096215 0,07747302 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02096215 0,0773542 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02096215 0,07723574 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02096215 0,07711764 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02096215 0,0769999 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02096215 0,07688253 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02096215 0,07676551 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02096215 0,07664884 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02096215 0,07653253 ! spinal cord patterning GO:0021511 13 7 0,000 0,02096215 0,07641657 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02096215 0,07630096 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02096215 0,07618571 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02096215 0,0760708 ! adrenal gland development GO:0030325 17 7 0,000 0,02096215 0,07595623 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02096215 0,07584201 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02096215 0,07572813 ! ovulation GO:0030728 9 7 0,000 0,02096215 0,0756146 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02096215 0,0755014 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02096215 0,07538855 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02096215 0,07527603 ! microtubule nucleation GO:0007020 20 7 0,000 0,02096215 0,07516384 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02096215 0,07505199 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02096215 0,07494047 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02096215 0,07482928 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02096215 0,07471843 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02096215 0,0746079 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02096215 0,07449769 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02096215 0,07438781 ! galactose metabolic process GO:0006012 13 7 0,000 0,02096215 0,07427826 ! vesicle fusion GO:0006906 17 7 0,000 0,02096215 0,07416903 ! response to dietary excess GO:0002021 8 7 0,000 0,02096215 0,07406011 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02096215 0,07395152 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02096215 0,07384325 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02096215 0,07373529 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02096215 0,07362765 ! organ growth GO:0035265 15 7 0,000 0,02096215 0,07352032 ! purine salvage GO:0043101 10 7 0,000 0,02096215 0,0734133 ! nucleoside transport GO:0015858 8 7 0,000 0,02096215 0,0733066 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02096215 0,0732002 ! parturition GO:0007567 14 7 0,000 0,02096215 0,07309411 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02096215 0,07298833 ! rRNA modification GO:0000154 14 7 0,000 0,02096215 0,07288286 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02096215 0,07277769 ! spindle checkpoint GO:0031577 15 7 0,000 0,02096215 0,07267282 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02096215 0,07256826 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02096215 0,07246399 ! macrophage differentiation GO:0030225 11 7 0,000 0,02096215 0,07236003 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02096215 0,07225636 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02096215 0,07215299 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02096215 0,07204991 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02096215 0,07194713 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02096215 0,07184464 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02096215 0,07174244 ! fibrinolysis GO:0042730 10 7 0,000 0,02096215 0,07164054 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02096215 0,07153892 ! eating behavior GO:0042755 7 7 0,000 0,02096215 0,07143759 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02096215 0,07133655 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02096215 0,07123579 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02096215 0,07113531 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02096215 0,07103512 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02096215 0,07093521 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02096215 0,07083559 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02096215 0,07073624 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02096215 0,07063717 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02096215 0,07053837 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02096215 0,07043986 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02096215 0,07034161 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02096215 0,07024365 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02096215 0,07014595 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02096215 0,07004852 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02096215 0,06995137 ! regulation of meiosis GO:0040020 12 7 0,000 0,02096215 0,06985448 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02096215 0,06975787 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02096215 0,06966152 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02096215 0,06956543 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02096215 0,06946961 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02096215 0,06937405 ! transcription termination GO:0006353 13 7 0,000 0,02096215 0,06927876 ! response to tumor cell GO:0002347 13 7 0,000 0,02096215 0,06918373 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02096215 0,06908896 ! anaphase GO:0051322 17 7 0,000 0,02096215 0,06899444 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02096215 0,06890019 ! axonal fasciculation GO:0007413 18 7 0,000 0,02096215 0,06880619 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02096215 0,06871245 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02096215 0,06861896 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02096215 0,06852573 ! diuresis GO:0030146 12 7 0,000 0,02096215 0,06843275 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02096215 0,06834002 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02096215 0,06824755 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02096215 0,06815532 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02096215 0,06806334 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02096215 0,06797161 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02096215 0,06788013 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02096215 0,06778889 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02096215 0,0676979 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02096215 0,06760715 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02096215 0,06751665 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02096215 0,06742639 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02096215 0,06733637 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02096215 0,06724658 ! lymph node development GO:0048535 10 7 0,000 0,02096215 0,06715704 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02096215 0,06706774 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02096215 0,06697867 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02096215 0,06688984 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02096215 0,06680124 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02096215 0,06671288 ! adult feeding behavior GO:0008343 9 7 0,000 0,02096215 0,06662475 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02096215 0,06653686 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02096215 0,06644919 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02096215 0,06636176 ! muscle adaptation GO:0043500 14 7 0,000 0,02096215 0,06627456 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02096215 0,06618758 ! retina homeostasis GO:0001895 12 7 0,000 0,02096215 0,06610084 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02096215 0,06601432 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02096215 0,06592802 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02096215 0,06584196 ! protein prenylation GO:0018342 18 7 0,000 0,02096215 0,06575611 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02096215 0,06567049 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02096215 0,06558509 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02096215 0,06549992 ! neurotransmitter transport GO:0006836 123 74 1,000 0,02118478 0,0661097 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,021723 0,06770147 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,02226688 0,06930674 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02281638 0,07092532 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02337145 0,07255706 ! protein oligomerization GO:0051259 139 78 1,000 0,02337145 0,07246355 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02392105 0,07407213 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02392105 0,07397693 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02392105 0,07388196 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02392105 0,07378724 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02392105 0,07369276 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02392105 0,07359853 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02392105 0,07350453 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02392105 0,07341078 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02392105 0,07331726 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02392105 0,07322398 ! meiotic prophase I GO:0007128 13 8 0,000 0,02392105 0,07313094 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02392105 0,07303813 ! oligopeptide transport GO:0006857 15 8 0,000 0,02392105 0,07294556 ! UTP metabolic process GO:0046051 8 8 0,000 0,02392105 0,07285323 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02392105 0,07276112 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02392105 0,07266925 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02392105 0,07257761 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02392105 0,07248621 ! succinate metabolic process GO:0006105 14 8 0,000 0,02392105 0,07239503 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02392105 0,07230408 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02392105 0,07221336 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02392105 0,07212287 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02392105 0,0720326 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02392105 0,07194256 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02392105 0,07185274 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02392105 0,07176315 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02392105 0,07167378 ! reflex GO:0060004 16 8 0,000 0,02392105 0,07158464 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02392105 0,07149571 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02392105 0,07140701 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02392105 0,07131852 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02392105 0,07123026 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02392105 0,07114221 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02392105 0,07105438 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02392105 0,07096677 ! pigment granule organization GO:0048753 16 8 0,000 0,02392105 0,07087937 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02392105 0,07079219 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02392105 0,07070522 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02392105 0,07061846 ! histidine metabolic process GO:0006547 16 8 0,000 0,02392105 0,07053192 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02392105 0,07044559 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02392105 0,07035947 ! glycine catabolic process GO:0006546 13 8 0,000 0,02392105 0,07027356 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02392105 0,07018786 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02392105 0,07010237 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02392105 0,07001709 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02392105 0,06993201 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02392105 0,06984715 ! melanin metabolic process GO:0006582 15 8 0,000 0,02392105 0,06976248 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02392105 0,06967802 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02392105 0,06959377 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02392105 0,06950972 ! macrophage activation GO:0042116 12 8 0,000 0,02392105 0,06942587 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02392105 0,06934223 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02392105 0,06925878 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02392105 0,06917554 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02392105 0,06909249 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02392105 0,06900965 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02392105 0,068927 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02392105 0,06884456 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02392105 0,0687623 ! osteoblast development GO:0002076 16 8 0,000 0,02392105 0,06868025 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02392105 0,06859839 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02392105 0,06851672 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02392105 0,06843525 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02392105 0,06835398 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02392105 0,06827289 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02392105 0,068192 ! response to UV-B GO:0010224 16 8 0,000 0,02392105 0,0681113 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02392105 0,06803079 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02392105 0,06795047 ! intermediate filament organization GO:0045109 12 8 0,000 0,02392105 0,06787034 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02392105 0,0677904 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02392105 0,06771064 ! cellular extravasation GO:0045123 12 8 0,000 0,02392105 0,06763108 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02392105 0,0675517 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02392105 0,06747251 ! response to antibiotic GO:0046677 11 8 0,000 0,02392105 0,0673935 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02392105 0,06731468 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02392105 0,06723604 ! DNA topological change GO:0006265 12 8 0,000 0,02392105 0,06715758 ! response to tropane GO:0014073 15 8 0,000 0,02392105 0,06707931 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02392105 0,06700122 ! melanosome transport GO:0032402 13 8 0,000 0,02392105 0,06692331 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02392105 0,06684558 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02392105 0,06676804 ! mast cell activation GO:0045576 14 8 0,000 0,02392105 0,06669067 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02392105 0,06661348 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02392105 0,06653647 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02392105 0,06645964 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02392105 0,06638299 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02392105 0,06630651 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02392105 0,06623021 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02392105 0,06615408 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02392105 0,06607813 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02392105 0,06600235 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02392105 0,06592674 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02392105 0,06585131 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02392105 0,06577606 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02392105 0,06570097 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02392105 0,06562605 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02392105 0,06555131 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02392105 0,06547673 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02392105 0,06540233 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02392105 0,06532809 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02392105 0,06525402 ! hormone catabolic process GO:0042447 17 8 0,000 0,02392105 0,06518012 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02392105 0,06510639 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02392105 0,06503282 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02392105 0,06495942 ! ATP catabolic process GO:0006200 11 8 0,000 0,02392105 0,06488619 ! blastocyst growth GO:0001832 19 8 0,000 0,02392105 0,06481312 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02392105 0,06474021 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02392105 0,06466747 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02392105 0,06459489 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02392105 0,06452248 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02392105 0,06445022 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02392105 0,06437813 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02392105 0,0643062 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02392105 0,06423443 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02392105 0,06416282 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02392105 0,06409137 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02392105 0,06402008 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02392105 0,06394894 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02392105 0,06387797 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02392105 0,06380715 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02392105 0,06373649 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02392105 0,06366598 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02392105 0,06359563 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,02393208 0,06355472 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,02393208 0,06348464 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02393208 0,06341473 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,02393208 0,06334496 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,0244982 0,06477217 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02506979 0,06621068 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 155 84 1,000 0,02681701 0,0707475 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,02681701 0,07067001 ! axon extension GO:0048675 15 9 0,000 0,02687111 0,0707351 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02687111 0,07065779 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02687111 0,07058065 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02687111 0,07050368 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02687111 0,07042688 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02687111 0,07035025 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02687111 0,07027378 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02687111 0,07019748 ! phosphate transport GO:0006817 19 9 0,000 0,02687111 0,07012134 ! reproductive behavior GO:0019098 19 9 0,000 0,02687111 0,07004537 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02687111 0,06996957 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02687111 0,06989392 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02687111 0,06981844 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02687111 0,06974313 ! GTP metabolic process GO:0046039 9 9 0,000 0,02687111 0,06966797 ! RNA methylation GO:0001510 15 9 0,000 0,02687111 0,06959298 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02687111 0,06951815 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02687111 0,06944348 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02687111 0,06936897 ! artery development GO:0060840 24 9 0,000 0,02687111 0,06929462 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02687111 0,06922043 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02687111 0,06914639 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02687111 0,06907252 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02687111 0,0689988 ! chemosensory behavior GO:0007635 20 9 0,000 0,02687111 0,06892524 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02687111 0,06885184 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02687111 0,06877859 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02687111 0,0687055 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02687111 0,06863257 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02687111 0,06855979 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02687111 0,06848716 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02687111 0,06841469 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02687111 0,06834237 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02687111 0,0682702 ! protein targeting to ER GO:0045047 22 9 0,000 0,02687111 0,06819818 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02687111 0,06812632 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02687111 0,06805461 ! T cell selection GO:0045058 23 9 0,000 0,02687111 0,06798305 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02687111 0,06791164 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02687111 0,06784038 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02687111 0,06776926 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02687111 0,0676983 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02687111 0,06762749 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02687111 0,06755682 ! mannose metabolic process GO:0006013 13 9 0,000 0,02687111 0,0674863 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02687111 0,06741593 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02687111 0,06734571 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02687111 0,06727563 ! receptor clustering GO:0043113 18 9 0,000 0,02687111 0,0672057 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02687111 0,06713591 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02687111 0,06706626 ! ruffle organization GO:0031529 15 9 0,000 0,02687111 0,06699677 ! retinol metabolic process GO:0042572 18 9 0,000 0,02687111 0,06692741 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02687111 0,0668582 ! behavioral fear response GO:0001662 22 9 0,000 0,02687111 0,06678913 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02687111 0,06672021 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02687111 0,06665142 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02687111 0,06658278 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02687111 0,06651428 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02687111 0,06644592 ! segment specification GO:0007379 13 9 0,000 0,02687111 0,0663777 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02687111 0,06630962 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02687111 0,06624168 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02687111 0,06617388 ! response to amine stimulus GO:0014075 13 9 0,000 0,02687111 0,06610622 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02687111 0,06603869 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02687111 0,0659713 ! erythrocyte development GO:0048821 15 9 0,000 0,02687111 0,06590406 ! gas homeostasis GO:0033483 16 9 0,000 0,02687111 0,06583694 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02687111 0,06576997 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02687111 0,06570313 ! renal water homeostasis GO:0003091 14 9 0,000 0,02687111 0,06563643 ! postreplication repair GO:0006301 22 9 0,000 0,02687111 0,06556986 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02687111 0,06550342 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02687111 0,06543712 ! icosanoid secretion GO:0032309 15 9 0,000 0,02687111 0,06537096 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02687111 0,06530493 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02687111 0,06523903 ! regulation of cell division GO:0051302 15 9 0,000 0,02687111 0,06517326 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02687111 0,06510763 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02687111 0,06504213 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02687111 0,06497676 ! sterol catabolic process GO:0016127 11 9 0,000 0,02687111 0,06491152 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02687111 0,06484642 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02687111 0,06478144 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02687111 0,0647166 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02687111 0,06465188 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02687111 0,06458729 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02687111 0,06452283 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02687111 0,0644585 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02687111 0,0643943 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02687111 0,06433023 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02687111 0,06426628 ! purine base metabolic process GO:0006144 21 9 0,000 0,02687111 0,06420246 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02687111 0,06413877 ! pigment granule transport GO:0051904 17 9 0,000 0,02687111 0,0640752 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02687111 0,06401176 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02687111 0,06394845 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02687111 0,06388526 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02687111 0,06382219 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02687111 0,06375925 ! nucleosome assembly GO:0006334 122 85 1,000 0,0274101 0,06497408 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0274101 0,06491013 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,02800847 0,06626193 ! gland development GO:0048732 206 88 1,000 0,02922092 0,0690624 ! regulation of neurological system process GO:0031644 148 88 1,000 0,02922092 0,06899463 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02922092 0,06892699 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02981234 0,07025318 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02981234 0,07018443 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02981234 0,07011583 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02981234 0,07004736 ! synapsis GO:0007129 13 10 0,000 0,02981234 0,06997902 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02981234 0,06991081 ! N-glycan processing GO:0006491 20 10 0,000 0,02981234 0,06984274 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02981234 0,0697748 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02981234 0,06970699 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02981234 0,06963931 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02981234 0,06957177 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02981234 0,06950435 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02981234 0,06943707 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02981234 0,06936992 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02981234 0,06930289 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02981234 0,069236 ! androgen metabolic process GO:0008209 17 10 0,000 0,02981234 0,06916923 ! phospholipid efflux GO:0033700 16 10 0,000 0,02981234 0,06910259 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02981234 0,06903608 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02981234 0,0689697 ! lung alveolus development GO:0048286 26 10 0,000 0,02981234 0,06890345 ! pathogenesis GO:0009405 13 10 0,000 0,02981234 0,06883732 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02981234 0,06877133 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02981234 0,06870545 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02981234 0,06863971 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02981234 0,06857408 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02981234 0,06850859 ! endoderm development GO:0007492 16 10 0,000 0,02981234 0,06844322 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02981234 0,06837797 ! arginine catabolic process GO:0006527 13 10 0,000 0,02981234 0,06831285 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02981234 0,06824785 ! proline metabolic process GO:0006560 13 10 0,000 0,02981234 0,06818298 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02981234 0,06811823 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02981234 0,0680536 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02981234 0,06798909 ! V(D)J recombination GO:0033151 28 10 0,000 0,02981234 0,06792471 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02981234 0,06786045 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02981234 0,06779631 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02981234 0,06773229 ! B cell proliferation GO:0042100 18 10 0,000 0,02981234 0,06766839 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02981234 0,06760461 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02981234 0,06754095 ! multicellular organism growth GO:0035264 18 10 0,000 0,02981234 0,06747742 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02981234 0,067414 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02981234 0,0673507 ! epithelial cell development GO:0002064 20 10 0,000 0,02981234 0,06728752 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02981234 0,06722445 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02981234 0,06716151 ! macroautophagy GO:0016236 17 10 0,000 0,02981234 0,06709868 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02981234 0,06703597 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02981234 0,06697338 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02981234 0,06691091 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02981234 0,06684855 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02981234 0,06678631 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02981234 0,06672418 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02981234 0,06666217 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02981234 0,06660027 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02981234 0,06653849 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02981234 0,06647682 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02981234 0,06641527 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02981234 0,06635383 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02981234 0,06629251 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02981234 0,06623129 ! response to dsRNA GO:0043331 20 10 0,000 0,02981234 0,0661702 ! DNA ligation GO:0006266 19 10 0,000 0,02981234 0,06610921 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02981234 0,06604834 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02981234 0,06598757 ! melanosome localization GO:0032400 16 10 0,000 0,02981234 0,06592692 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02981234 0,06586638 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02981234 0,06580596 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02981234 0,06574564 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02981234 0,06568543 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02981234 0,06562534 ! mRNA cleavage GO:0006379 17 10 0,000 0,02981234 0,06556535 ! protein sumoylation GO:0016925 15 10 0,000 0,02981234 0,06550547 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02981234 0,0654457 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02981234 0,06538605 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02981234 0,0653265 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02981234 0,06526705 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02981234 0,06520772 ! salivary gland development GO:0007431 27 10 0,000 0,02981234 0,06514849 ! prophase GO:0051324 15 10 0,000 0,02981234 0,06508938 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02981234 0,06503036 ! apical protein localization GO:0045176 15 10 0,000 0,02981234 0,06497146 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02981234 0,06491266 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02981234 0,06485397 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02981234 0,06479539 ! midbrain development GO:0030901 13 10 0,000 0,02981234 0,06473691 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02981234 0,06467853 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02981234 0,06462026 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02981234 0,0645621 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02981234 0,06450404 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02981234 0,06444608 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02981234 0,06438823 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02981234 0,06433049 ! detection of calcium ion GO:0005513 23 10 0,000 0,02981234 0,06427284 ! oocyte development GO:0048599 17 10 0,000 0,02981234 0,0642153 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02981234 0,06415786 ! blastocyst formation GO:0001825 17 10 0,000 0,02981234 0,06410053 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02981234 0,0640433 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02981234 0,06398617 ! activation of innate immune response GO:0002218 12 10 0,000 0,02981234 0,06392914 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02981234 0,06387221 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02981234 0,06381538 ! response to nicotine GO:0035094 20 10 0,000 0,02981234 0,06375866 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02981234 0,06370204 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02981234 0,06364551 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02981234 0,06358909 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02983492 0,06358088 ! ossification GO:0001503 188 90 1,000 0,03045405 0,06484288 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03045405 0,06478555 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,03045405 0,06472832 ! bone development GO:0060348 189 91 1,000 0,03107829 0,0659968 ! nucleosome organization GO:0034728 138 92 1,000 0,0317076 0,06727379 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03234193 0,06855919 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03234193 0,06849884 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03274478 0,06929107 ! respiratory burst GO:0045730 17 11 0,000 0,03274478 0,06923019 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03274478 0,0691694 ! neuron fate specification GO:0048665 17 11 0,000 0,03274478 0,06910873 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03274478 0,06904816 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03274478 0,0689877 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03274478 0,06892734 ! thyroid gland development GO:0030878 26 11 0,000 0,03274478 0,06886709 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03274478 0,06880694 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03274478 0,0687469 ! response to pain GO:0048265 24 11 0,000 0,03274478 0,06868697 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03274478 0,06862714 ! T cell proliferation GO:0042098 26 11 0,000 0,03274478 0,06856741 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03274478 0,06850778 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03274478 0,06844826 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03274478 0,06838885 ! bone resorption GO:0045453 16 11 0,000 0,03274478 0,06832953 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03274478 0,06827032 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03274478 0,06821121 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03274478 0,06815221 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03274478 0,0680933 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03274478 0,0680345 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03274478 0,0679758 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03274478 0,0679172 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03274478 0,0678587 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03274478 0,0678003 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03274478 0,067742 ! lipid digestion GO:0044241 18 11 0,000 0,03274478 0,06768381 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03274478 0,06762571 ! UV protection GO:0009650 19 11 0,000 0,03274478 0,06756771 ! adult heart development GO:0007512 14 11 0,000 0,03274478 0,06750981 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03274478 0,06745201 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03274478 0,06739431 ! temperature homeostasis GO:0001659 17 11 0,000 0,03274478 0,06733671 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03274478 0,06727921 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03274478 0,0672218 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03274478 0,06716449 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03274478 0,06710728 ! regulation of organ growth GO:0046620 13 11 0,000 0,03274478 0,06705017 ! pigment granule localization GO:0051875 20 11 0,000 0,03274478 0,06699316 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03274478 0,06693624 ! vasoconstriction GO:0042310 18 11 0,000 0,03274478 0,06687942 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03274478 0,06682269 ! embryonic axis specification GO:0000578 18 11 0,000 0,03274478 0,06676606 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03274478 0,06670953 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03274478 0,06665309 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03274478 0,06659675 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03274478 0,0665405 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03274478 0,06648435 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03274478 0,06642829 ! zymogen activation GO:0031638 15 11 0,000 0,03274478 0,06637233 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03274478 0,06631646 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03274478 0,06626068 ! nucleosome positioning GO:0016584 15 11 0,000 0,03274478 0,066205 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03274478 0,06614941 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03274478 0,06609392 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03274478 0,06603852 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03274478 0,06598321 ! acid secretion GO:0046717 18 11 0,000 0,03274478 0,06592799 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03274478 0,06587287 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03274478 0,06581784 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03274478 0,0657629 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03274478 0,06570805 ! oocyte differentiation GO:0009994 18 11 0,000 0,03274478 0,06565329 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03274478 0,06559863 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03274478 0,06554405 ! cholesterol efflux GO:0033344 19 11 0,000 0,03274478 0,06548957 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03274478 0,06543518 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03274478 0,06538087 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03274478 0,06532666 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03274478 0,06527254 ! embryonic gut development GO:0048566 15 11 0,000 0,03274478 0,0652185 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03274478 0,06516456 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03274478 0,0651107 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03274478 0,06505694 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03274478 0,06500326 ! defense response to fungus GO:0050832 13 11 0,000 0,03274478 0,06494967 ! lysogeny GO:0030069 21 11 0,000 0,03274478 0,06489617 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03274478 0,06484276 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03274478 0,06478943 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03274478 0,0647362 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03274478 0,06468305 ! nucleus localization GO:0051647 19 11 0,000 0,03274478 0,06462998 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03274478 0,06457701 ! female pregnancy GO:0007565 164 94 1,000 0,03298126 0,06499009 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03298126 0,06493691 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,03492885 0,0687153 ! hormone metabolic process GO:0042445 157 97 1,000 0,03492885 0,06865916 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,0355878 0,06989735 GO:0016054|organic acid catabolic process, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03566846 0,06999863 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03566846 0,06994158 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03566846 0,06988462 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03566846 0,06982776 ! cartilage condensation GO:0001502 20 12 0,000 0,03566846 0,06977099 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03566846 0,06971431 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03566846 0,06965773 ! protein complex disassembly GO:0043241 27 12 0,000 0,03566846 0,06960123 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03566846 0,06954483 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03566846 0,06948852 ! hippocampus development GO:0021766 26 12 0,000 0,03566846 0,0694323 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03566846 0,06937617 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03566846 0,06932013 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03566846 0,06926418 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03566846 0,06920832 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03566846 0,06915255 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03566846 0,06909687 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03566846 0,06904129 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03566846 0,06898579 ! drug transport GO:0015893 16 12 0,000 0,03566846 0,06893038 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03566846 0,06887506 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03566846 0,06881982 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03566846 0,06876468 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03566846 0,06870962 ! focal adhesion formation GO:0048041 35 12 0,000 0,03566846 0,06865465 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03566846 0,06859978 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03566846 0,06854498 ! forebrain cell migration GO:0021885 21 12 0,000 0,03566846 0,06849028 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03566846 0,06843566 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03566846 0,06838113 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03566846 0,06832669 ! entry into host cell GO:0030260 32 12 0,000 0,03566846 0,06827233 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03566846 0,06821806 ! monoamine transport GO:0015844 18 12 0,000 0,03566846 0,06816387 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03566846 0,06810978 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03566846 0,06805576 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03566846 0,06800184 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03566846 0,067948 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03566846 0,06789424 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03566846 0,06784057 ! protein homotetramerization GO:0051289 21 12 0,000 0,03566846 0,06778698 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03566846 0,06773348 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03566846 0,06768006 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03566846 0,06762673 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03566846 0,06757348 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03566846 0,06752031 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03566846 0,06746723 ! cranial nerve development GO:0021545 20 12 0,000 0,03566846 0,06741423 ! fucose catabolic process GO:0019317 22 12 0,000 0,03566846 0,06736132 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03566846 0,06730849 ! histone acetylation GO:0016573 26 12 0,000 0,03566846 0,06725574 ! histone methylation GO:0016571 26 12 0,000 0,03566846 0,06720307 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03566846 0,06715048 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03566846 0,06709798 ! gland morphogenesis GO:0022612 29 12 0,000 0,03566846 0,06704556 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03566846 0,06699322 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03566846 0,06694097 ! T cell homeostasis GO:0043029 25 12 0,000 0,03566846 0,06688879 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03566846 0,0668367 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03566846 0,06678468 ! spleen development GO:0048536 22 12 0,000 0,03566846 0,06673275 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03566846 0,0666809 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03566846 0,06662913 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03566846 0,06657744 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03566846 0,06652583 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03566846 0,0664743 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03566846 0,06642285 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03566846 0,06637148 ! response to cold GO:0009409 17 12 0,000 0,03566846 0,06632018 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03566846 0,06626897 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03566846 0,06621784 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03625157 0,06724849 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,03692013 0,06843593 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0385834 0,07146394 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0385834 0,07140897 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0385834 0,07135408 ! peroxisomal transport GO:0043574 24 13 0,000 0,0385834 0,07129928 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0385834 0,07124456 ! lipid localization GO:0010876 28 13 0,000 0,0385834 0,07118992 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,0385834 0,07113537 ! organelle fusion GO:0048284 32 13 0,000 0,0385834 0,0710809 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0385834 0,07102652 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0385834 0,07097221 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0385834 0,070918 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0385834 0,07086386 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0385834 0,07080981 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0385834 0,07075584 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0385834 0,07070195 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0385834 0,07064814 ! methionine metabolic process GO:0006555 27 13 0,000 0,0385834 0,07059442 ! plasma membrane organization GO:0007009 24 13 0,000 0,0385834 0,07054077 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0385834 0,07048721 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,0385834 0,07043373 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0385834 0,07038033 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,0385834 0,07032701 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0385834 0,07027377 ! response to X-ray GO:0010165 25 13 0,000 0,0385834 0,07022062 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0385834 0,07016754 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,0385834 0,07011454 ! exocrine system development GO:0035272 32 13 0,000 0,0385834 0,07006163 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0385834 0,07000879 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0385834 0,06995603 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0385834 0,06990336 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0385834 0,06985076 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0385834 0,06979824 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0385834 0,0697458 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0385834 0,06969344 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,0385834 0,06964115 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0385834 0,06958895 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0385834 0,06953682 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0385834 0,06948477 ! ribosome assembly GO:0042255 17 13 0,000 0,0385834 0,0694328 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0385834 0,06938091 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0385834 0,06932909 ! chromatin silencing GO:0006342 26 13 0,000 0,0385834 0,06927736 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0385834 0,06922569 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0385834 0,06917411 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0385834 0,0691226 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,0385834 0,06907117 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0385834 0,06901982 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0385834 0,06896854 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0385834 0,06891734 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0385834 0,06886621 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0385834 0,06881516 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0385834 0,06876419 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0385834 0,06871329 ! embryonic placenta development GO:0001892 23 13 0,000 0,0385834 0,06866247 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0385834 0,06861172 ! insulin secretion GO:0030073 23 13 0,000 0,0385834 0,06856105 ! actin filament polymerization GO:0030041 24 13 0,000 0,0385834 0,06851045 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,0385834 0,06845992 ! acrosome reaction GO:0007340 18 13 0,000 0,0385834 0,06840947 ! rRNA transcription GO:0009303 25 14 0,000 0,04148962 0,07350812 ! lactation GO:0007595 26 14 0,000 0,04148962 0,07345403 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,04148962 0,07340002 ! reproductive cellular process GO:0048610 20 14 0,000 0,04148962 0,07334609 ! tRNA modification GO:0006400 20 14 0,000 0,04148962 0,07329224 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04148962 0,07323846 ! regulation of S phase GO:0033261 23 14 0,000 0,04148962 0,07318477 ! water transport GO:0006833 21 14 0,000 0,04148962 0,07313116 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04148962 0,07307762 ! non-recombinational repair GO:0000726 25 14 0,000 0,04148962 0,07302416 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04148962 0,07297078 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04148962 0,07291748 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04148962 0,07286425 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04148962 0,07281111 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04148962 0,07275804 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04148962 0,07270504 ! palate development GO:0060021 31 14 0,000 0,04148962 0,07265213 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04148962 0,07259929 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04148962 0,07254653 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04148962 0,07249385 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04148962 0,07244124 ! arginine metabolic process GO:0006525 17 14 0,000 0,04148962 0,07238871 ! regulation of heart rate GO:0002027 24 14 0,000 0,04148962 0,07233625 ! organic alcohol transport GO:0015850 29 14 0,000 0,04148962 0,07228387 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04148962 0,07223157 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04148962 0,07217934 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04148962 0,07212719 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04148962 0,07207511 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04148962 0,07202311 ! L-amino acid transport GO:0015807 30 14 0,000 0,04148962 0,07197118 ! bone mineralization GO:0030282 17 14 0,000 0,04148962 0,07191933 ! stem cell development GO:0048864 43 14 0,000 0,04148962 0,07186755 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04148962 0,07181585 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04148962 0,07176422 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04148962 0,07171266 ! cerebellum development GO:0021549 21 14 0,000 0,04148962 0,07166118 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04148962 0,07160978 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04148962 0,07155844 ! response to gamma radiation GO:0010332 28 14 0,000 0,04148962 0,07150718 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04148962 0,071456 ! cofactor transport GO:0051181 26 14 0,000 0,04148962 0,07140488 ! NADP metabolic process GO:0006739 24 14 0,000 0,04148962 0,07135384 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04148962 0,07130288 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04148962 0,07125198 ! intestinal absorption GO:0050892 25 14 0,000 0,04148962 0,07120116 ! oxygen transport GO:0015671 21 14 0,000 0,04148962 0,07115041 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04148962 0,07109973 ! male genitalia development GO:0030539 24 14 0,000 0,04148962 0,07104913 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04148962 0,0709986 ! regulation of axon extension GO:0030516 37 14 0,000 0,04148962 0,07094814 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,04148962 0,07089775 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04148962 0,07084743 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04438715 0,07574148 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04438715 0,0756878 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04438715 0,0756342 ! superoxide anion generation GO:0042554 20 15 0,000 0,04438715 0,07558067 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04438715 0,07552722 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04438715 0,07547385 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04438715 0,07542055 ! copper ion transport GO:0006825 20 15 0,000 0,04438715 0,07536732 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04438715 0,07531417 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04438715 0,07526109 ! sulfate transport GO:0008272 23 15 0,000 0,04438715 0,07520809 ! response to cAMP GO:0051591 22 15 0,000 0,04438715 0,07515517 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04438715 0,07510231 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04438715 0,07504954 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04438715 0,07499683 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04438715 0,0749442 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04438715 0,07489165 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04438715 0,07483917 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04438715 0,07478676 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04438715 0,07473442 ! pituitary gland development GO:0021983 29 15 0,000 0,04438715 0,07468216 ! vesicle coating GO:0006901 33 15 0,000 0,04438715 0,07462997 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04438715 0,07457786 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04438715 0,07452581 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04438715 0,07447384 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04438715 0,07442195 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04438715 0,07437012 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04438715 0,07431837 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04438715 0,07426668 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04438715 0,07421507 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04438715 0,07416354 ! histone deacetylation GO:0016575 20 15 0,000 0,04438715 0,07411207 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04438715 0,07406067 ! tissue regeneration GO:0042246 26 15 0,000 0,04438715 0,07400935 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04438715 0,0739581 ! water homeostasis GO:0030104 27 15 0,000 0,04438715 0,07390691 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04438715 0,0738558 ! muscle maintenance GO:0046716 26 15 0,000 0,04438715 0,07380476 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04438715 0,07375379 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04438715 0,07370289 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04438715 0,07365206 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04438715 0,0736013 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04438715 0,07355061 ! detection of bacterium GO:0016045 18 15 0,000 0,04438715 0,07349999 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04438715 0,07344944 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04438715 0,07339896 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04438715 0,07334855 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04438715 0,07329821 ! peptide hormone processing GO:0016486 23 15 0,000 0,04438715 0,07324794 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04727602 0,0779617 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04727602 0,0779083 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04727602 0,07785497 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04727602 0,07780172 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04727602 0,07774854 ! bone remodeling GO:0046849 27 16 0,000 0,04727602 0,07769543 ! filopodium assembly GO:0046847 32 16 0,000 0,04727602 0,0776424 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04727602 0,07758944 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04727602 0,07753655 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04727602 0,07748373 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04727602 0,07743098 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04727602 0,07737831 ! startle response GO:0001964 28 16 0,000 0,04727602 0,07732571 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04727602 0,07727317 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04727602 0,07722072 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04727602 0,07716833 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04727602 0,07711601 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04727602 0,07706376 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04727602 0,07701159 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04727602 0,07695948 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04727602 0,07690745 ! response to osmotic stress GO:0006970 25 16 0,000 0,04727602 0,07685548 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04727602 0,07680359 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04727602 0,07675176 ! fructose metabolic process GO:0006000 25 16 0,000 0,04727602 0,07670001 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04727602 0,07664832 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04727602 0,07659671 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04727602 0,07654516 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04727602 0,07649369 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04727602 0,07644228 ! axon cargo transport GO:0008088 43 16 0,000 0,04727602 0,07639094 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04727602 0,07633967 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04727602 0,07628847 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04727602 0,07623734 ! DNA replication initiation GO:0006270 27 16 0,000 0,04727602 0,07618628 ! neuron recognition GO:0008038 35 16 0,000 0,04727602 0,07613528 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04727602 0,07608436 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04727602 0,0760335 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04727602 0,07598271 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04727602 0,07593198 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04727602 0,07588133 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04727602 0,07583074 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04727602 0,07578022 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04727602 0,07572977 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04727602 0,07567938 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04727602 0,07562906 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04727602 0,07557881 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04727602 0,07552863 ! defense response to virus GO:0051607 37 16 0,000 0,04727602 0,07547851 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05015626 0,08002384 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05015626 0,07997081 ! metencephalon development GO:0022037 30 17 0,000 0,05015626 0,07991785 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05015626 0,07986496 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05015626 0,07981214 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05015626 0,07975939 ! signal complex assembly GO:0007172 41 17 0,000 0,05015626 0,07970671 ! endothelial cell migration GO:0043542 28 17 0,000 0,05015626 0,07965409 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05015626 0,07960155 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05015626 0,07954908 ! glial cell development GO:0021782 27 17 0,000 0,05015626 0,07949668 ! limbic system development GO:0021761 36 17 0,000 0,05015626 0,07944434 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05015626 0,07939207 ! adult walking behavior GO:0007628 33 17 0,000 0,05015626 0,07933988 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05015626 0,07928775 ! heart looping GO:0001947 30 17 0,000 0,05015626 0,07923569 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05015626 0,0791837 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05015626 0,07913177 ! myoblast differentiation GO:0045445 45 17 0,000 0,05015626 0,07907992 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05015626 0,07902813 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05015626 0,07897641 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05015626 0,07892476 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05015626 0,07887317 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05015626 0,07882165 ! glycine metabolic process GO:0006544 28 17 0,000 0,05015626 0,0787702 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05015626 0,07871882 ! NAD metabolic process GO:0019674 29 17 0,000 0,05015626 0,07866751 ! membrane budding GO:0006900 37 17 0,000 0,05015626 0,07861626 ! DNA integration GO:0015074 29 17 0,000 0,05015626 0,07856507 ! regulation of protein binding GO:0043393 33 17 0,000 0,05015626 0,07851396 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05015626 0,07846291 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05015626 0,07841193 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05015626 0,07836101 ! genitalia development GO:0048806 30 17 0,000 0,05015626 0,07831016 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05015626 0,07825937 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05015626 0,07820865 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05015626 0,078158 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05015626 0,07810741 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05015626 0,07805689 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05015626 0,07800643 ! steroid catabolic process GO:0006706 31 17 0,000 0,05015626 0,07795604 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05015626 0,07790572 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05015626 0,07785545 ! gas transport GO:0015669 25 17 0,000 0,05015626 0,07780526 ! organic cation transport GO:0015695 31 17 0,000 0,05015626 0,07775512 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05015626 0,07770506 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05015626 0,07765505 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05015626 0,07760511 ! microspike assembly GO:0030035 36 17 0,000 0,05015626 0,07755524 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05015626 0,07750543 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05015626 0,07745568 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05302788 0,08183776 ! neuron maturation GO:0042551 42 18 0,000 0,05302788 0,0817853 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05302788 0,08173291 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05302788 0,08168058 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05302788 0,08162833 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05302788 0,08157613 ! memory GO:0007613 31 18 0,000 0,05302788 0,08152401 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05302788 0,08147195 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05302788 0,08141996 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05302788 0,08136803 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05302788 0,08131617 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05302788 0,08126438 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05302788 0,08121265 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05302788 0,08116099 ! response to retinoic acid GO:0032526 26 18 0,000 0,05302788 0,08110939 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05302788 0,08105786 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05302788 0,0810064 ! response to fungus GO:0009620 21 18 0,000 0,05302788 0,080955 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05302788 0,08090366 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05302788 0,08085239 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05302788 0,08080119 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05302788 0,08075005 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05302788 0,08069897 ! vitamin transport GO:0051180 27 18 0,000 0,05302788 0,08064796 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05302788 0,08059701 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05302788 0,08054613 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05302788 0,08049531 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05302788 0,08044456 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05302788 0,08039387 ! nerve development GO:0021675 28 18 0,000 0,05302788 0,08034324 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05302788 0,08029268 ! protein secretion GO:0009306 39 19 0,000 0,05589091 0,08457455 ! positive regulation of translation GO:0045727 30 19 0,000 0,05589091 0,08452139 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05589091 0,0844683 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05589091 0,08441527 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05589091 0,08436232 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05589091 0,08430942 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05589091 0,0842566 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05589091 0,08420384 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05589091 0,08415115 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05589091 0,08409852 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05589091 0,08404596 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05589091 0,08399346 ! cerebral cortex development GO:0021987 36 19 0,000 0,05589091 0,08394103 ! pigmentation during development GO:0048066 41 19 0,000 0,05589091 0,08388867 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05589091 0,08383637 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05589091 0,08378413 ! heme metabolic process GO:0042168 36 19 0,000 0,05589091 0,08373196 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05589091 0,08367986 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05589091 0,08362782 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05589091 0,08357584 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05589091 0,08352393 ! peptide cross-linking GO:0018149 37 19 0,000 0,05589091 0,08347209 ! protein export from nucleus GO:0006611 36 19 0,000 0,05589091 0,08342031 ! heart process GO:0003015 30 19 0,000 0,05589091 0,08336859 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05589091 0,08331693 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05589091 0,08326535 ! visual learning GO:0008542 36 19 0,000 0,05589091 0,08321382 ! cellular pigmentation GO:0033059 36 19 0,000 0,05589091 0,08316236 ! G1 phase GO:0051318 40 19 0,000 0,05589091 0,08311096 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05589091 0,08305962 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05589091 0,08300835 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05589091 0,08295715 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05589091 0,082906 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05589091 0,08285492 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05589091 0,0828039 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05589091 0,08275294 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05589091 0,08270205 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05589091 0,08265122 ! cilium assembly GO:0042384 37 19 0,000 0,05589091 0,08260045 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05589091 0,08254974 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05874538 0,08671251 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05874538 0,08665935 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05874538 0,08660625 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05874538 0,08655321 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05874538 0,08650024 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,05874538 0,08644734 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,05874538 0,0863945 ! response to vitamin GO:0033273 31 20 0,000 0,05874538 0,08634172 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05874538 0,08628901 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05874538 0,08623636 ! response to alkaloid GO:0043279 38 20 0,000 0,05874538 0,08618378 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05874538 0,08613126 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05874538 0,0860788 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,05874538 0,08602641 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05874538 0,08597408 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05874538 0,08592182 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05874538 0,08586962 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05874538 0,08581748 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05874538 0,08576541 ! body fluid secretion GO:0007589 31 20 0,000 0,05874538 0,0857134 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05874538 0,08566145 ! peptide secretion GO:0002790 35 20 0,000 0,05874538 0,08560957 ! stem cell differentiation GO:0048863 53 20 0,000 0,05874538 0,08555774 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05874538 0,08550599 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05874538 0,08545429 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05874538 0,08540266 ! sensory perception of pain GO:0019233 30 20 0,000 0,05874538 0,08535108 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05874538 0,08529957 ! diencephalon development GO:0021536 34 20 0,000 0,05874538 0,08524813 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05874538 0,08519674 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05874538 0,08514542 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05874538 0,08509416 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05874538 0,08504296 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05874538 0,08499182 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05874538 0,08494074 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05874538 0,08488973 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05874538 0,08483877 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05874538 0,08478788 ! regulation of glucose import GO:0046324 29 20 0,000 0,05874538 0,08473705 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05874538 0,08468628 ! actin filament-based movement GO:0030048 43 20 0,000 0,05874538 0,08463557 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05874538 0,08458492 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05874538 0,08453433 ! negative regulation of translation GO:0017148 29 20 0,000 0,05874538 0,0844838 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05874538 0,08443333 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05874538 0,08438292 ! regulation of cell killing GO:0031341 42 21 0,000 0,06159132 0,08841809 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06159132 0,08836537 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06159132 0,08831271 ! hormone secretion GO:0046879 38 21 0,000 0,06159132 0,08826011 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06159132 0,08820757 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06159132 0,0881551 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06159132 0,08810269 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06159132 0,08805034 ! axis specification GO:0009798 38 21 0,000 0,06159132 0,08799805 ! ovarian follicle development GO:0001541 35 21 0,000 0,06159132 0,08794583 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06159132 0,08789366 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06159132 0,08784156 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06159132 0,08778953 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06159132 0,08773755 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06159132 0,08768563 ! cell aging GO:0007569 44 21 0,000 0,06159132 0,08763378 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06159132 0,08758199 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06159132 0,08753025 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06159132 0,08747858 ! cytolysis GO:0019835 24 21 0,000 0,06159132 0,08742697 ! vasodilation GO:0042311 39 21 0,000 0,06159132 0,08737542 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06159132 0,08732394 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06159132 0,08727251 ! oogenesis GO:0048477 36 21 0,000 0,06159132 0,08722114 ! DNA modification GO:0006304 34 21 0,000 0,06159132 0,08716983 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06159132 0,08711859 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06159132 0,0870674 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06159132 0,08701628 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06159132 0,08696521 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06159132 0,0869142 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06159132 0,08686326 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06159132 0,08681237 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06159132 0,08676155 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06159132 0,08671078 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06159132 0,08666007 ! collagen catabolic process GO:0030574 28 21 0,000 0,06159132 0,08660942 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06159132 0,08655883 ! gut development GO:0048565 39 21 0,000 0,06159132 0,0865083 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06442875 0,09044082 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06442875 0,09038809 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06442875 0,09033541 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06442875 0,0902828 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06442875 0,09023025 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06442875 0,09017776 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06442875 0,09012533 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06442875 0,09007296 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06442875 0,09002065 ! regeneration GO:0031099 41 22 0,000 0,06442875 0,08996841 ! keratinization GO:0031424 28 22 0,000 0,06442875 0,08991622 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06442875 0,0898641 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06442875 0,08981203 ! sensory perception of taste GO:0050909 28 22 0,000 0,06442875 0,08976003 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,06442875 0,08970808 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06442875 0,0896562 ! vacuolar transport GO:0007034 36 22 0,000 0,06442875 0,08960437 ! lysosome organization GO:0007040 41 22 0,000 0,06442875 0,08955261 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06442875 0,0895009 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06442875 0,08944926 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06442875 0,08939767 ! fucose metabolic process GO:0006004 39 22 0,000 0,06442875 0,08934615 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06442875 0,08929468 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06442875 0,08924327 ! ureteric bud development GO:0001657 43 22 0,000 0,06442875 0,08919193 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06442875 0,08914064 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06442875 0,08908941 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06442875 0,08903824 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,06442875 0,08898712 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06442875 0,08893607 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06442875 0,08888507 ! sarcomere organization GO:0045214 30 22 0,000 0,06442875 0,08883414 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06442875 0,08878326 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06442875 0,08873244 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06442875 0,08868167 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06442875 0,08863097 ! protein stabilization GO:0050821 39 22 0,000 0,06442875 0,08858032 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06725769 0,0924169 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06725769 0,09236416 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06725769 0,09231147 ! gluconeogenesis GO:0006094 33 23 0,000 0,06725769 0,09225884 ! viral genome replication GO:0019079 41 23 0,000 0,06725769 0,09220627 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06725769 0,09215376 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06725769 0,09210131 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06725769 0,09204892 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06725769 0,09199659 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06725769 0,09194432 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06725769 0,09189211 ! visual behavior GO:0007632 42 23 0,000 0,06725769 0,09183995 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06725769 0,09178786 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06725769 0,09173583 ! response to ethanol GO:0045471 46 23 0,000 0,06725769 0,09168385 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06725769 0,09163194 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06725769 0,09158008 ! peroxisome organization GO:0007031 37 23 0,000 0,06725769 0,09152828 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06725769 0,09147654 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06725769 0,09142486 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06725769 0,09137324 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06725769 0,09132167 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06725769 0,09127016 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06725769 0,09121871 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06725769 0,09116732 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06725769 0,09111599 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06725769 0,09106472 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06725769 0,0910135 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06725769 0,09096234 ! fatty acid transport GO:0015908 44 23 0,000 0,06725769 0,09091124 ! platelet activation GO:0030168 37 23 0,000 0,06725769 0,09086019 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06725769 0,0908092 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06725769 0,09075827 ! hormone transport GO:0009914 40 23 0,000 0,06725769 0,0907074 ! cell-cell recognition GO:0009988 25 23 0,000 0,06725769 0,09065658 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06725769 0,09060582 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06725769 0,09055512 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06725769 0,09050447 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06725769 0,09045388 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,07007817 0,09419446 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07007817 0,09414186 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07007817 0,09408933 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07007817 0,09403685 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07007817 0,09398444 ! vesicle docking GO:0048278 47 24 0,000 0,07007817 0,09393208 ! spinal cord development GO:0021510 47 24 0,000 0,07007817 0,09387978 ! vacuole organization GO:0007033 43 24 0,000 0,07007817 0,09382753 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07007817 0,09377535 ! digestive system process GO:0022600 39 24 0,000 0,07007817 0,09372322 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07007817 0,09367115 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07007817 0,09361914 ! regulation of behavior GO:0050795 43 24 0,000 0,07007817 0,09356719 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07007817 0,09351529 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07007817 0,09346346 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07007817 0,09341168 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07007817 0,09335995 ! membrane depolarization GO:0051899 39 24 0,000 0,07007817 0,09330829 ! pallium development GO:0021543 49 24 0,000 0,07007817 0,09325668 ! pentose metabolic process GO:0019321 35 24 0,000 0,07007817 0,09320513 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07007817 0,09315363 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07007817 0,0931022 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07007817 0,09305081 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07007817 0,09299949 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07007817 0,09294822 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07007817 0,09289701 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07007817 0,09284586 ! regulation of amine transport GO:0051952 40 24 0,000 0,07007817 0,09279476 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07289022 0,09646527 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07289022 0,09641224 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07289022 0,09635926 ! phototransduction GO:0007602 33 25 0,000 0,07289022 0,09630635 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07289022 0,09625349 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07289022 0,09620069 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,07289022 0,09614795 ! sperm motility GO:0030317 31 25 0,000 0,07289022 0,09609526 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07289022 0,09604264 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,07289022 0,09599007 ! receptor metabolic process GO:0043112 46 25 0,000 0,07289022 0,09593756 ! chromosome condensation GO:0030261 45 25 0,000 0,07289022 0,09588511 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07289022 0,09583271 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,07289022 0,09578037 ! neural crest cell development GO:0014032 54 25 0,000 0,07289022 0,09572809 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07289022 0,09567586 ! negative regulation of cell development GO:0010721 73 25 0,000 0,07289022 0,0956237 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07289022 0,09557158 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07289022 0,09551953 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07289022 0,09546753 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07289022 0,09541559 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,07289022 0,09536371 ! immunoglobulin production GO:0002377 55 25 0,000 0,07289022 0,09531188 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07289022 0,09526011 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07289022 0,09520839 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07289022 0,09515673 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07289022 0,09510513 ! telomere organization GO:0032200 43 25 0,000 0,07289022 0,09505358 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07289022 0,09500209 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07289022 0,09495065 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07569385 0,09854946 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07569385 0,09849616 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07569385 0,09844292 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07569385 0,09838974 ! initiation of viral infection GO:0019059 57 26 0,000 0,07569385 0,09833661 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07569385 0,09828354 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07569385 0,09823053 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07569385 0,09817758 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07569385 0,09812468 ! molting cycle process GO:0022404 50 26 0,000 0,07569385 0,09807184 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07569385 0,09801906 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07569385 0,09796633 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07569385 0,09791366 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07569385 0,09786104 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07569385 0,09780849 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07569385 0,09775599 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07569385 0,09770354 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07569385 0,09765116 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07569385 0,09759882 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07569385 0,09754655 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07569385 0,09749433 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07569385 0,09744216 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07569385 0,09739006 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07569385 0,097338 ! blastocyst development GO:0001824 49 26 0,000 0,07569385 0,09728601 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07569385 0,09723407 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07569385 0,09718218 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07569385 0,09713035 ! neuron fate commitment GO:0048663 48 27 0,000 0,0784891 0,10066353 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0784891 0,1006099 ! iron ion transport GO:0006826 59 27 0,000 0,0784891 0,10055632 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0784891 0,10050281 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0784891 0,10044935 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0784891 0,10039595 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0784891 0,1003426 ! fat cell differentiation GO:0045444 50 27 0,000 0,0784891 0,10028931 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0784891 0,10023608 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0784891 0,1001829 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0784891 0,10012979 ! autophagy GO:0006914 41 27 0,000 0,0784891 0,10007672 ! male gonad development GO:0008584 44 27 0,000 0,0784891 0,10002372 ! response to toxin GO:0009636 47 27 0,000 0,0784891 0,09997077 ! primary neural tube formation GO:0014020 51 27 0,000 0,0784891 0,09991787 ! base-excision repair GO:0006284 41 27 0,000 0,0784891 0,09986503 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0784891 0,09981225 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0784891 0,09975952 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0784891 0,09970685 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0784891 0,09965424 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0784891 0,09960167 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08127599 0,10308383 ! circadian rhythm GO:0007623 50 28 0,000 0,08127599 0,10302952 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08127599 0,10297527 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08127599 0,10292107 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08127599 0,10286693 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08127599 0,10281284 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,08127599 0,10275882 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08127599 0,10270485 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08127599 0,10265093 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08127599 0,10259708 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08127599 0,10254328 ! synaptogenesis GO:0007416 42 28 0,000 0,08127599 0,10248953 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08127599 0,10243585 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08127599 0,10238221 ! translational initiation GO:0006413 65 29 0,000 0,08405454 0,10582691 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08405454 0,10577156 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08405454 0,10571627 ! regulation of pH GO:0006885 43 29 0,000 0,08405454 0,10566104 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08405454 0,10560586 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08405454 0,10555075 ! catechol metabolic process GO:0009712 54 29 0,000 0,08405454 0,10549569 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08405454 0,10544068 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08405454 0,10538574 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08405454 0,10533085 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08405454 0,10527602 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08405454 0,10522124 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08405454 0,10516653 ! cell fate determination GO:0001709 60 29 0,000 0,08405454 0,10511187 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08405454 0,10505726 ! detection of light stimulus GO:0009583 38 29 0,000 0,08405454 0,10500272 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08405454 0,10494822 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08405454 0,10489379 ! tissue homeostasis GO:0001894 48 29 0,000 0,08405454 0,10483941 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08405454 0,10478509 ! phenol metabolic process GO:0018958 55 30 0,000 0,08682478 0,10818251 ! zinc ion transport GO:0006829 45 30 0,000 0,08682478 0,10812652 ! membrane docking GO:0022406 61 30 0,000 0,08682478 0,10807058 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08682478 0,1080147 ! cell junction assembly GO:0034329 78 30 0,000 0,08682478 0,10795888 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08682478 0,10790312 ! acute-phase response GO:0006953 49 30 0,000 0,08682478 0,10784741 ! myofibril assembly GO:0030239 47 30 0,000 0,08682478 0,10779176 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08682478 0,10773617 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08682478 0,10768063 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08682478 0,10762516 ! phospholipid transport GO:0015914 51 30 0,000 0,08682478 0,10756974 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08682478 0,10751438 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08682478 0,10745907 ! eye morphogenesis GO:0048592 60 30 0,000 0,08682478 0,10740382 ! response to heat GO:0009408 50 30 0,000 0,08682478 0,10734863 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08958674 0,11070657 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08958674 0,11064974 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08958674 0,11059297 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08958674 0,11053625 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08958674 0,1104796 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08958674 0,110423 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08958674 0,11036646 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08958674 0,11030998 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08958674 0,11025355 ! ovulation cycle process GO:0022602 49 31 0,000 0,08958674 0,11019719 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08958674 0,11014088 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08958674 0,11008462 ! peptide transport GO:0015833 55 31 0,000 0,08958674 0,11002843 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08958674 0,10997229 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08958674 0,10991621 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08958674 0,10986019 ! mesoderm formation GO:0001707 69 31 0,000 0,08958674 0,10980423 ! natural killer cell activation GO:0030101 45 31 0,000 0,08958674 0,10974832 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08958674 0,10969247 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08958674 0,10963667 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,08958674 0,10958093 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08958674 0,10952525 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09234043 0,11283447 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09234043 0,1127772 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09234043 0,11271998 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09234043 0,11266282 ! cholesterol transport GO:0030301 56 32 0,000 0,09234043 0,11260572 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09234043 0,11254867 ! spliceosome assembly GO:0000245 67 32 0,000 0,09234043 0,11249169 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09234043 0,11243476 ! metanephros development GO:0001656 74 32 0,000 0,09234043 0,11237789 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09234043 0,11232107 ! response to ionizing radiation GO:0010212 65 32 0,000 0,09234043 0,11226432 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09234043 0,11220762 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,09234043 0,11215097 ! muscle cell development GO:0055001 49 32 0,000 0,09234043 0,11209439 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09234043 0,11203786 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09234043 0,11198139 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09234043 0,11192498 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09234043 0,11186862 ! ovulation cycle GO:0042698 51 32 0,000 0,09234043 0,11181232 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09234043 0,11175608 ! hindbrain development GO:0030902 61 32 0,000 0,09234043 0,11169989 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09234043 0,11164376 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09234043 0,11158768 ! gene silencing GO:0016458 65 32 0,000 0,09234043 0,11153167 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,09508589 0,11479009 ! post-embryonic development GO:0009791 69 33 0,000 0,09508589 0,11473252 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,09508589 0,11467501 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09508589 0,11461756 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09508589 0,11456016 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09508589 0,11450283 ! sterol transport GO:0015918 57 33 0,000 0,09508589 0,11444555 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09508589 0,11438832 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09508589 0,11433116 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09508589 0,11427405 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,09508589 0,114217 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09508589 0,11416 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09782313 0,11738776 ! glial cell differentiation GO:0010001 63 34 0,000 0,09782313 0,11732924 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09782313 0,11727078 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09782313 0,11721238 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09782313 0,11715403 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09782313 0,11709575 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09782313 0,11703752 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09782313 0,11697935 ! mismatch repair GO:0006298 46 34 0,000 0,09782313 0,11692124 ! spermatid development GO:0007286 63 34 0,000 0,09782313 0,11686318 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09782313 0,11680519 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09782313 0,11674725 ! placenta development GO:0001890 53 34 0,000 0,09782313 0,11668937 ! regulation of muscle development GO:0048634 70 35 0,000 0,10055218 0,11988531 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,10055218 0,11982593 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10055218 0,11976661 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,10055218 0,11970735 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10055218 0,11964815 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10055218 0,119589 ! female gonad development GO:0008585 58 35 0,000 0,10055218 0,11952992 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10055218 0,11947089 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10055218 0,11941192 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,10055218 0,11935301 ! cytokine production GO:0001816 59 35 0,000 0,10055218 0,11929416 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10055218 0,11923536 ! neural tube formation GO:0001841 67 35 0,000 0,10055218 0,11917663 ! vesicle localization GO:0051648 64 35 0,000 0,10055218 0,11911795 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,10327307 0,12228101 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10327307 0,12222086 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10327307 0,12216077 ! cell junction organization GO:0034330 86 36 0,000 0,10327307 0,12210074 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10327307 0,12204077 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,10327307 0,12198086 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,10327307 0,121921 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10327307 0,12186121 ! aerobic respiration GO:0009060 55 36 0,000 0,10327307 0,12180147 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,10327307 0,1217418 ! embryonic organ development GO:0048568 57 36 0,000 0,10327307 0,12168218 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10327307 0,12162262 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10598582 0,1247563 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10598582 0,12469529 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10598582 0,12463435 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10598582 0,12457346 ! organic anion transport GO:0015711 68 37 0,000 0,10598582 0,12451264 ! tissue remodeling GO:0048771 76 37 0,000 0,10598582 0,12445187 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,10598582 0,12439116 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,10598582 0,12433051 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10598582 0,12426992 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10598582 0,12420939 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,10598582 0,12414892 ! glycogen metabolic process GO:0005977 61 37 0,000 0,10598582 0,1240885 ! pigment metabolic process GO:0042440 80 37 0,000 0,10598582 0,12402815 ! spermatid differentiation GO:0048515 66 37 0,000 0,10598582 0,12396785 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10869045 0,12706959 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10869045 0,12700788 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10869045 0,12694622 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,10869045 0,12688463 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10869045 0,12682309 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,10869045 0,12676162 ! lipid homeostasis GO:0055088 67 38 0,000 0,10869045 0,1267002 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10869045 0,12663885 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10869045 0,12657755 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10869045 0,12651631 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10869045 0,12645513 ! glucan metabolic process GO:0044042 62 38 0,000 0,10869045 0,12639402 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11138699 0,12946719 ! learning GO:0007612 77 39 0,000 0,11138699 0,12940468 ! ear morphogenesis GO:0042471 60 39 0,000 0,11138699 0,12934222 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11138699 0,12927983 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11138699 0,1292175 ! segmentation GO:0035282 67 39 0,000 0,11138699 0,12915522 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11138699 0,12909301 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11138699 0,12903086 ! RNA modification GO:0009451 57 39 0,000 0,11138699 0,12896876 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11138699 0,12890673 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11407546 0,13195459 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11407546 0,13189118 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11407546 0,13182783 ! feeding behavior GO:0007631 59 40 0,000 0,11407546 0,13176454 ! negative regulation of binding GO:0051100 72 40 0,000 0,11407546 0,13170132 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11407546 0,13163815 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11407546 0,13157505 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11407546 0,131512 ! maintenance of protein location GO:0045185 91 40 0,000 0,11407546 0,13144902 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11675588 0,13447326 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11675588 0,13440892 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11675588 0,13434464 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11675588 0,13428042 ! gliogenesis GO:0042063 88 41 0,000 0,11675588 0,13421627 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11675588 0,13415217 ! T cell differentiation GO:0030217 81 41 0,000 0,11675588 0,13408814 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,11675588 0,13402416 ! female gamete generation GO:0007292 61 41 0,000 0,11675588 0,13396025 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11675588 0,1338964 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,11942828 0,13689588 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,11942828 0,13683069 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,11942828 0,13676556 ! regulation of tube size GO:0035150 71 42 0,000 0,11942828 0,1367005 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11942828 0,1366355 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,11942828 0,13657056 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11942828 0,13650568 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,11942828 0,13644086 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11942828 0,1363761 ! neuron migration GO:0001764 79 42 0,000 0,11942828 0,13631141 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11942828 0,13624678 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,11942828 0,1361822 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12209269 0,13915444 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12209269 0,13908855 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12209269 0,13902272 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12209269 0,13895696 ! glucose transport GO:0015758 65 43 0,000 0,12209269 0,13889126 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12209269 0,13882562 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,12209269 0,13876004 ! neural tube development GO:0021915 77 43 0,000 0,12209269 0,13869453 ! striated muscle contraction GO:0006941 77 43 0,000 0,12209269 0,13862908 ! phagocytosis GO:0006909 90 43 0,000 0,12209269 0,13856369 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12209269 0,13849836 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12474912 0,14144505 ! hexose transport GO:0008645 67 44 0,000 0,12474912 0,14137842 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12474912 0,14131186 ! male sex differentiation GO:0046661 76 44 0,000 0,12474912 0,14124536 ! biopolymer methylation GO:0043414 84 44 0,000 0,12474912 0,14117892 ! B cell differentiation GO:0030183 107 44 0,000 0,12474912 0,14111255 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12474912 0,14104624 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12474912 0,14097999 ! developmental growth GO:0048589 82 44 0,000 0,12474912 0,1409138 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12739761 0,14383794 ! glycolysis GO:0006096 65 45 0,000 0,12739761 0,14377047 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,12739761 0,14370307 ! leukocyte migration GO:0050900 68 45 0,000 0,12739761 0,14363573 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,12739761 0,14356845 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,12739761 0,14350124 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12739761 0,14343409 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,12739761 0,143367 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12739761 0,14329997 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,12739761 0,14323301 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12739761 0,14316611 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13003816 0,14606528 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,13003816 0,14599712 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,13003816 0,14592902 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13003816 0,14586099 ! pigmentation GO:0043473 100 46 0,000 0,13003816 0,14579302 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,13003816 0,14572511 ! positive regulation of defense response GO:0031349 76 47 0,000 0,13267082 0,14860614 ! response to calcium ion GO:0051592 81 47 0,000 0,13267082 0,14853699 ! endosome transport GO:0016197 108 47 0,000 0,13267082 0,1484679 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,13267082 0,14839888 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13267082 0,14832992 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13267082 0,14826102 ! JNK cascade GO:0007254 91 47 0,000 0,13267082 0,14819219 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13267082 0,14812343 ! methylation GO:0032259 90 47 0,000 0,13267082 0,14805472 ! protein homooligomerization GO:0051260 76 47 0,000 0,13267082 0,14798609 ! mitochondrial transport GO:0006839 82 48 0,000 0,13529559 0,15084393 ! Notch signaling pathway GO:0007219 96 48 0,000 0,13529559 0,15077406 ! cellular component disassembly GO:0022411 86 48 0,000 0,13529559 0,15070426 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,13529559 0,15063452 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13529559 0,15056484 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13529559 0,15049523 ! activation of caspase activity GO:0006919 84 48 0,000 0,13529559 0,15042569 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13529559 0,15035621 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,13529559 0,15028679 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,13791251 0,15312298 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,13791251 0,15305235 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,13791251 0,15298179 ! regulation of ion transport GO:0043269 77 49 0,000 0,13791251 0,15291129 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,13791251 0,15284085 ! peptide metabolic process GO:0006518 76 49 0,000 0,13791251 0,15277049 ! response to temperature stimulus GO:0009266 76 49 0,000 0,13791251 0,15270018 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,13791251 0,15262994 ! endocrine system development GO:0035270 104 49 0,000 0,13791251 0,15255977 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,13791251 0,15248966 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,13791251 0,15241961 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,13791251 0,15234963 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,13791251 0,15227971 ! neuromuscular process GO:0050905 99 50 0,000 0,14052159 0,15508943 ! regulation of ossification GO:0030278 117 50 0,000 0,14052159 0,15501832 ! inner ear development GO:0048839 79 50 0,000 0,14052159 0,15494728 ! histone modification GO:0016570 91 50 0,000 0,14052159 0,1548763 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14052159 0,15480538 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14052159 0,15473453 ! viral infectious cycle GO:0019058 99 51 0,000 0,14312287 0,15752682 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,14312287 0,15745479 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,14312287 0,15738283 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,14312287 0,15731093 ! excretion GO:0007588 83 51 0,000 0,14312287 0,1572391 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,14312287 0,15716733 ! chromatin remodeling GO:0006338 109 51 0,000 0,14312287 0,15709563 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,14312287 0,157024 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,14312287 0,15695243 ! vesicle organization GO:0016050 107 51 0,000 0,14312287 0,15688092 ! regulation of cell shape GO:0008360 125 51 0,000 0,14312287 0,15680948 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,14312287 0,15673811 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,14571636 0,15950571 ! membrane fusion GO:0006944 110 52 0,000 0,14571636 0,15943318 ! covalent chromatin modification GO:0016569 101 52 0,000 0,14571636 0,15936071 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,14571636 0,1592883 ! cartilage development GO:0051216 90 52 0,000 0,14571636 0,15921596 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,14830208 0,16196768 ! RNA catabolic process GO:0006401 93 53 0,000 0,14830208 0,1618942 ! regulation of translational initiation GO:0006446 82 53 0,000 0,14830208 0,16182077 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,14830208 0,16174742 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,14830208 0,16167413 ! cell maturation GO:0048469 100 53 0,000 0,14830208 0,16160091 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,14830208 0,16152775 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,14830208 0,16145466 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,15088007 0,16418699 ! cell recognition GO:0008037 85 54 0,000 0,15088007 0,16411277 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15088007 0,16403861 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15088007 0,16396452 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15088007 0,16389049 ! chloride transport GO:0006821 90 55 0,000 0,15345033 0,16660717 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,15345033 0,16653202 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,15345033 0,16645694 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,15345033 0,16638193 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15345033 0,16630698 ! aging GO:0007568 103 55 0,000 0,15345033 0,1662321 ! gastrulation GO:0007369 112 55 0,000 0,15345033 0,16615729 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,15345033 0,16608255 ! RNA elongation GO:0006354 79 55 0,000 0,15345033 0,16600787 ! nuclear export GO:0051168 97 55 0,000 0,15345033 0,16593326 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,15345033 0,16585871 ! regulation of actin filament length GO:0030832 105 56 0,000 0,1560129 0,16855278 ! sensory perception of smell GO:0007608 80 56 0,000 0,1560129 0,16847713 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,1560129 0,16840155 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,1560129 0,16832603 ! proton transport GO:0015992 94 56 0,000 0,1560129 0,16825058 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,1585678 0,17092927 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,1585678 0,17085272 ! hydrogen transport GO:0006818 97 58 0,000 0,16111505 0,17351961 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,16111505 0,17344198 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16111505 0,17336441 ! adult behavior GO:0030534 99 58 0,000 0,16111505 0,17328691 ! positive regulation of secretion GO:0051047 95 59 0,000 0,16365468 0,17593974 ! regulation of cellular component size GO:0032535 109 59 0,000 0,16365468 0,17586117 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,16365468 0,17578266 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16365468 0,17570422 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,16365468 0,17562585 ! DNA catabolic process GO:0006308 86 59 0,000 0,16365468 0,17554755 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,16365468 0,17546932 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,16618669 0,17810476 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,16618669 0,17802546 ! regulation of heart contraction GO:0008016 110 60 0,000 0,16618669 0,17794623 ! camera-type eye development GO:0043010 116 60 0,000 0,16618669 0,17786708 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,16618669 0,17778799 ! kidney development GO:0001822 122 60 0,000 0,16618669 0,17770897 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,16871113 0,18032829 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,16871113 0,18024822 ! mesoderm development GO:0007498 119 61 0,000 0,16871113 0,18016821 ! tRNA processing GO:0008033 89 61 0,000 0,16871113 0,18008828 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,16871113 0,18000842 ! ear development GO:0043583 103 62 0,000 0,17122801 0,18261285 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17122801 0,18253194 ! gonad development GO:0008406 98 62 0,000 0,17122801 0,1824511 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,17122801 0,18237034 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,17373735 0,18496109 ! detection of external stimulus GO:0009581 91 63 0,000 0,17373735 0,18487929 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,17373735 0,18479755 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,17373735 0,18471589 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17623918 0,18729305 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17623918 0,18721036 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,17623918 0,18712774 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,17623918 0,1870452 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,17623918 0,18696273 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,17873351 0,18952527 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,17873351 0,18944178 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,17873351 0,18935836 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,17873351 0,18927501 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,17873351 0,18919174 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18122038 0,19173977 ! actin filament organization GO:0007015 148 66 0,000 0,18122038 0,19165548 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18122038 0,19157128 ! secondary metabolic process GO:0019748 116 66 0,000 0,18122038 0,19148714 ! developmental maturation GO:0021700 116 66 0,000 0,18122038 0,19140308 ! cell projection assembly GO:0030031 120 66 0,000 0,18122038 0,1913191 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,18369979 0,19385162 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18369979 0,19376664 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,18369979 0,19368173 ! hexose catabolic process GO:0019320 104 67 0,000 0,18369979 0,19359689 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,18369979 0,19351213 ! adaptive immune response GO:0002250 119 67 0,000 0,18369979 0,19342744 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,18369979 0,19334283 ! amino acid transport GO:0006865 125 68 0,000 0,18617178 0,1958589 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18617178 0,1957733 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,18617178 0,19568777 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,18617178 0,19560232 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,18617178 0,19551694 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,18617178 0,19543164 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,18863637 0,19793245 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,18863637 0,19784617 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,18863637 0,19775996 ! urogenital system development GO:0001655 137 69 0,000 0,18863637 0,19767383 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,18863637 0,19758777 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,18863637 0,19750179 ! antigen processing and presentation GO:0019882 104 69 0,000 0,18863637 0,19741588 ! appendage morphogenesis GO:0035107 135 70 0,000 0,19109358 0,1999005 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,19354342 0,20237526 ! reproductive structure development GO:0048608 113 71 0,000 0,19354342 0,20228735 ! appendage development GO:0048736 136 71 0,000 0,19354342 0,20219951 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,19354342 0,20211175 ! B cell activation GO:0042113 160 71 0,000 0,19354342 0,20202406 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,19354342 0,20193646 ! regulation of immune effector process GO:0002697 137 71 0,000 0,19354342 0,20184892 ! acute inflammatory response GO:0002526 113 72 0,000 0,19598593 0,20430769 ! regulation of caspase activity GO:0043281 122 72 0,000 0,19598593 0,2042192 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,19598593 0,2041308 ! carbohydrate transport GO:0008643 110 72 0,000 0,19598593 0,20404247 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,19598593 0,20395421 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,19598593 0,20386603 ! learning or memory GO:0007611 147 73 0,000 0,19842112 0,20630994 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,19842112 0,20622082 ! fertilization GO:0009566 90 73 0,000 0,19842112 0,20613178 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,20084901 0,20856397 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,20084901 0,208474 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,20084901 0,2083841 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,20084901 0,20829428 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,20084901 0,20820453 ! eye development GO:0001654 143 74 0,000 0,20084901 0,20811487 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,20326963 0,21053239 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,20326963 0,2104418 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,20326963 0,21035128 ! rhythmic process GO:0048511 128 75 0,000 0,20326963 0,21026085 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,20326963 0,21017049 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,205683 0,21257444 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,205683 0,21248317 ! defense response to bacterium GO:0042742 89 76 0,000 0,205683 0,21239198 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,205683 0,21230086 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,20808914 0,21469231 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,20808914 0,21460029 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,20808914 0,21450835 ! blood coagulation GO:0007596 146 78 0,000 0,21048807 0,21688835 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21048807 0,21679551 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,21048807 0,21670274 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,21287982 0,21907136 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,21287982 0,2189777 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,21287982 0,21888412 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,21526439 0,22124141 ! response to metal ion GO:0010038 140 80 0,000 0,21526439 0,22114694 ! muscle cell differentiation GO:0042692 159 80 0,000 0,21526439 0,22105255 ! protein import into nucleus GO:0006606 158 80 0,000 0,21526439 0,22095825 ! inorganic anion transport GO:0015698 138 80 0,000 0,21526439 0,22086402 ! T cell activation GO:0042110 168 81 0,000 0,21764183 0,22320811 ! response to hypoxia GO:0001666 171 81 0,000 0,21764183 0,22311301 ! digestion GO:0007586 112 81 0,000 0,21764183 0,22301799 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,21764183 0,22292305 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,21764183 0,22282819 ! nuclear import GO:0051170 161 81 0,000 0,21764183 0,22273341 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,22001214 0,22506344 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,22001214 0,22496779 ! response to drug GO:0042493 143 82 0,000 0,22001214 0,22487222 ! response to nutrient GO:0007584 125 82 0,000 0,22001214 0,22477673 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,22001214 0,22468132 ! response to oxygen levels GO:0070482 176 83 0,000 0,22237534 0,22699833 ! regulation of lyase activity GO:0051339 160 83 0,000 0,22237534 0,22690207 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,22473147 0,22920895 ! hemostasis GO:0007599 158 84 0,000 0,22473147 0,22911183 ! negative regulation of transport GO:0051051 153 84 0,000 0,22473147 0,22901479 ! regulation of ligase activity GO:0051340 142 84 0,000 0,22473147 0,22891783 ! response to unfolded protein GO:0006986 131 85 0,000 0,22708053 0,23121276 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,22708053 0,23111496 ! amine biosynthetic process GO:0009309 138 86 0,000 0,22942256 0,23339986 ! response to inorganic substance GO:0010035 153 86 0,000 0,22942256 0,23330121 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,22942256 0,23320265 ! tube morphogenesis GO:0035239 176 86 0,000 0,22942256 0,23310417 ! mitochondrion organization GO:0007005 148 86 0,000 0,22942256 0,23300577 ! alcohol catabolic process GO:0046164 130 86 0,000 0,22942256 0,23290745 ! amine transport GO:0015837 155 86 0,000 0,22942256 0,23280922 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,23175756 0,23507955 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,23175756 0,23498048 ! protein localization in nucleus GO:0034504 176 87 0,000 0,23175756 0,2348815 ! regulation of protein transport GO:0051223 154 87 0,000 0,23175756 0,23478261 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,23408557 0,23704119 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,23408557 0,23694147 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,23408557 0,23684183 ! cellular defense response GO:0006968 114 89 0,000 0,2364066 0,23908965 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,23872067 0,24132854 ! sex differentiation GO:0007548 145 90 0,000 0,23872067 0,24122719 ! sterol metabolic process GO:0016125 152 91 0,000 0,24102781 0,2434563 ! response to protein stimulus GO:0051789 149 91 0,000 0,24102781 0,24335414 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,24102781 0,24325206 ! regulation of defense response GO:0031347 149 92 0,000 0,24332803 0,24547054 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,24332803 0,24536766 ! vitamin metabolic process GO:0006766 139 92 0,000 0,24332803 0,24526487 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,24562136 0,24747278 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,24562136 0,24736919 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,24562136 0,24726569 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,24790781 0,24946307 ! transcription initiation GO:0006352 153 94 0,000 0,24790781 0,24935878 ! forebrain development GO:0030900 188 95 0,000 0,25018741 0,25154656 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,25018741 0,25144148 ! leukocyte differentiation GO:0002521 202 96 0,000 0,25246017 0,2536197 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,25246017 0,25351385 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,25246017 0,25340809 ! positive regulation of immune response GO:0050778 156 96 0,000 0,25246017 0,25330241 ! detection of stimulus GO:0051606 151 96 0,000 0,25246017 0,25319682 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,25472613 0,25536294 ! protein ubiquitination GO:0016567 217 97 0,000 0,25472613 0,25525658 ! regulation of protein localization GO:0032880 176 97 0,000 0,25472613 0,25515032 ! response to virus GO:0009615 160 98 0,000 0,25698528 0,25730611 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,25698528 0,25719908 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,25923767 0,25934546 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,25923767 0,25923767