pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6909-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 4,000 1,885E-08 4,606E-05 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,234E-06 1,508E-03 ! positive regulation of axonogenesis GO:0050772 33 15 2,000 9,884E-06 8,049E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,762E-05 0,01075903 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,854E-05 0,01394223 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 3,423E-05 0,01393643 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 4,316E-05 0,01506163 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 4,607E-05 0,01406764 ! negative regulation of kinase activity GO:0033673 145 70 3,000 4,875E-05 0,0132336 ! interaction with host GO:0051701 66 25 2,000 4,894E-05 0,01195612 ! negative regulation of transferase activity GO:0051348 155 74 3,000 6,065E-05 0,01346986 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 6,198E-05 0,01261867 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 6,198E-05 0,01164801 ! positive regulation of glycolysis GO:0045821 13 5 1,000 7,95E-05 0,01387316 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 7,95E-05 0,01294828 ! meiotic chromosome segregation GO:0045132 10 5 1,000 7,95E-05 0,01213901 ! protein insertion into membrane GO:0051205 17 5 1,000 7,95E-05 0,01142495 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 9,447E-05 0,01282156 ! exocytosis GO:0006887 153 83 3,000 9,498E-05 0,01221305 ! regulation of neuron differentiation GO:0045664 187 85 3,000 1,042E-04 0,01272866 ! regulation of axonogenesis GO:0050770 86 33 2,000 1,142E-04 0,01328454 ! positive regulation of neurogenesis GO:0050769 72 33 2,000 1,142E-04 0,0126807 ! activation of MAPKKK activity GO:0000185 12 6 1,000 1,19E-04 0,01264329 ! establishment of spindle localization GO:0051293 16 6 1,000 1,19E-04 0,01211648 GO:0051653|spindle localization, ! interaction with symbiont GO:0051702 14 6 1,000 1,19E-04 0,01163183 ! progesterone metabolic process GO:0042448 12 6 1,000 1,19E-04 0,01118445 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 1,25E-04 0,01130898 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,477E-04 0,01288457 ! positive regulation of cell development GO:0010720 85 36 2,000 1,485E-04 0,01251135 ! male sex determination GO:0030238 15 7 1,000 1,663E-04 0,01354528 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,748E-04 0,01377171 ! regulation of neuron projection development GO:0010975 102 39 2,000 1,889E-04 0,01442335 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 2,000 1,889E-04 0,01398628 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,214E-04 0,01590607 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 2,214E-04 0,01545161 ! regulation of respiratory burst GO:0060263 12 8 1,000 2,214E-04 0,0150224 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,841E-04 0,01875765 ! regulation of glycolysis GO:0006110 20 9 1,000 2,841E-04 0,01826402 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,841E-04 0,01779571 ! mitochondrion localization GO:0051646 18 9 1,000 2,841E-04 0,01735082 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 2,897E-04 0,01726418 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 3,093E-04 0,01799183 ! response to insulin stimulus GO:0032868 98 47 2,000 3,297E-04 0,01873298 ! positive regulation of cell cycle GO:0045787 96 48 2,000 3,51E-04 0,01948753 ! regulation of developmental growth GO:0048638 16 10 1,000 3,545E-04 0,01924294 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,545E-04 0,01882462 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,545E-04 0,0184241 ! motor axon guidance GO:0008045 22 10 1,000 3,545E-04 0,01804026 ! protein heterooligomerization GO:0051291 17 10 1,000 3,545E-04 0,01767209 ! induction of an organ GO:0001759 17 10 1,000 3,545E-04 0,01731865 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 3,545E-04 0,01697907 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of mast cell proliferation GO:0070666 89 49 2,000 3,731E-04 0,01752872 ! regulation of cell projection organization GO:0031344 135 51 2,000 4,2E-04 0,01935933 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 4,324E-04 0,01956296 ! negative regulation of proteolysis GO:0045861 25 11 1,000 4,324E-04 0,01920727 ! regulation of embryonic development GO:0045995 35 11 1,000 4,324E-04 0,01886428 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 4,705E-04 0,02016586 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 5,179E-04 0,02181604 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 5,179E-04 0,02144628 ! virus-host interaction GO:0019048 30 12 1,000 5,179E-04 0,02108884 ! regulation of B cell proliferation GO:0030888 22 12 1,000 5,179E-04 0,02074312 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 5,179E-04 0,02040855 GO:0042130|negative regulation of T cell proliferation, ! developmental induction GO:0031128 22 12 1,000 5,179E-04 0,02008461 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 5,179E-04 0,01977079 ! response to UV GO:0009411 120 55 2,000 5,248E-04 0,01972303 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 5,829E-04 0,02157493 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 6,11E-04 0,0222779 GO:0000725|recombinational repair, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 6,11E-04 0,02195029 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 6,11E-04 0,02163217 ! positive regulation of cell migration GO:0030335 137 58 2,000 6,134E-04 0,02140756 ! lipid modification GO:0030258 112 60 2,000 6,775E-04 0,023311 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 8,181E-04 0,02775852 ! cAMP biosynthetic process GO:0006171 25 15 1,000 8,194E-04 0,02742271 ! cell killing GO:0001906 32 15 1,000 8,194E-04 0,02705214 ! positive regulation of cell motion GO:0051272 157 65 2,000 8,559E-04 0,02788024 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 9,348E-04 0,03004738 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 1,000 9,348E-04 0,02965716 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 9,348E-04 0,02927694 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell cycle process GO:0010948 35 17 1,000 1,057E-03 0,03269987 ! activation of MAPKK activity GO:0000186 43 17 1,000 1,057E-03 0,03229112 ! epidermis morphogenesis GO:0048730 43 18 1,000 1,187E-03 0,03581261 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 1,187E-03 0,03537587 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,187E-03 0,03494965 ! organelle localization GO:0051640 155 74 2,000 1,247E-03 0,03626631 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 1,325E-03 0,0380717 ! inositol metabolic process GO:0006020 33 19 1,000 1,325E-03 0,03762901 ! neuromuscular junction development GO:0007528 43 19 1,000 1,325E-03 0,03719649 ! regulation of catabolic process GO:0009894 173 77 2,000 1,399E-03 0,03882436 ! skin development GO:0043588 42 20 1,000 1,469E-03 0,04032593 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,469E-03 0,03987786 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,469E-03 0,03943964 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of T cell activation GO:0050868 41 20 1,000 1,469E-03 0,03901095 ! meiosis GO:0007126 143 81 2,000 1,618E-03 0,04249879 GO:0051327|M phase of meiotic cell cycle, ! lipid phosphorylation GO:0046834 43 21 1,000 1,621E-03 0,04212191 ! cAMP metabolic process GO:0046058 41 21 1,000 1,621E-03 0,04167852 ! C21-steroid hormone metabolic process GO:0008207 38 21 1,000 1,621E-03 0,04124437 ! regulation of vasoconstriction GO:0019229 40 21 1,000 1,621E-03 0,04081917 ! collagen fibril organization GO:0030199 62 21 1,000 1,621E-03 0,04040265 ! meiotic cell cycle GO:0051321 144 82 2,000 1,676E-03 0,04135426 ! cellular response to starvation GO:0009267 37 22 1,000 1,78E-03 0,04347351 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,78E-03 0,04304308 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 1,78E-03 0,04262109 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,858E-03 0,04405895 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,945E-03 0,04569788 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 2,118E-03 0,04928617 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,118E-03 0,04882121 ! sex determination GO:0007530 48 24 1,000 2,118E-03 0,04836493 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 2,118E-03 0,04791711 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 2,118E-03 0,0474775 ! negative regulation of catabolic process GO:0009895 52 24 1,000 2,118E-03 0,04704589 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,298E-03 0,05058248 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 2,298E-03 0,05013085 ! protein tetramerization GO:0051262 57 25 1,000 2,298E-03 0,04968722 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 2,401E-03 0,05144973 ! myelination GO:0042552 50 26 1,000 2,485E-03 0,05279395 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 2,485E-03 0,05233883 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,485E-03 0,05189149 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 41 26 1,000 2,485E-03 0,05145173 GO:0045840|positive regulation of mitosis, ! response to starvation GO:0042594 47 27 1,000 2,679E-03 0,05499911 ! regulation of chromosome organization GO:0033044 49 27 1,000 2,679E-03 0,05454078 ! cellular response to nutrient levels GO:0031669 45 27 1,000 2,679E-03 0,05409003 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 2,679E-03 0,05364667 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,785E-03 0,05532148 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,88E-03 0,05673652 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,88E-03 0,05628263 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 1,000 2,88E-03 0,05583594 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 2,88E-03 0,05539629 ! lipid oxidation GO:0034440 48 28 1,000 2,88E-03 0,05496351 GO:0019395|fatty acid oxidation, ! neurotransmitter secretion GO:0007269 55 30 1,000 3,302E-03 0,06252977 ! regulation of B cell activation GO:0050864 55 30 1,000 3,302E-03 0,06204877 ! ensheathment of neurons GO:0007272 64 31 1,000 3,523E-03 0,06570018 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 3,523E-03 0,06520245 ! fatty acid catabolic process GO:0009062 54 31 1,000 3,523E-03 0,0647122 ! spindle organization GO:0007051 50 32 1,000 3,751E-03 0,06838479 ! peripheral nervous system development GO:0007422 68 32 1,000 3,751E-03 0,06787824 ! positive regulation of catabolic process GO:0009896 72 32 1,000 3,751E-03 0,06737913 ! cell fate specification GO:0001708 56 34 1,000 4,227E-03 0,0753739 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 4,475E-03 0,07921636 ! calcium-mediated signaling GO:0019722 67 35 1,000 4,475E-03 0,07864646 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 4,729E-03 0,08252547 ! regulation of proteolysis GO:0030162 77 36 1,000 4,729E-03 0,08194018 ! sister chromatid segregation GO:0000819 65 37 1,000 4,99E-03 0,0858539 ! odontogenesis GO:0042476 74 37 1,000 4,99E-03 0,08525352 ! hormone biosynthetic process GO:0042446 62 37 1,000 4,99E-03 0,08466148 ! negative regulation of cell activation GO:0050866 69 37 1,000 4,99E-03 0,08407761 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 5,258E-03 0,08797827 ! meiosis I GO:0007127 74 38 1,000 5,258E-03 0,08737978 ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 5,258E-03 0,08678937 ! carbohydrate homeostasis GO:0033500 59 39 1,000 5,532E-03 0,09069929 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 5,532E-03 0,09009462 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 5,812E-03 0,09403483 ! regulation of action potential in neuron GO:0019228 80 40 1,000 5,812E-03 0,09341618 ! Rho protein signal transduction GO:0007266 88 40 1,000 5,812E-03 0,09280562 ! regulation of T cell differentiation GO:0045580 78 42 1,000 6,392E-03 0,10140337 ! cytokinesis GO:0000910 84 42 1,000 6,392E-03 0,10074915 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 6,692E-03 0,10479312 ! regulation of T cell proliferation GO:0042129 80 43 1,000 6,692E-03 0,10412565 ! double-strand break repair GO:0006302 85 44 1,000 6,997E-03 0,10819409 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 7,309E-03 0,1123072 ! polyol metabolic process GO:0019751 77 45 1,000 7,309E-03 0,11160528 ! maintenance of location in cell GO:0051651 101 45 1,000 7,309E-03 0,11091208 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 7,628E-03 0,11502575 ! cell growth GO:0016049 90 46 1,000 7,628E-03 0,11432007 ! positive regulation of DNA binding GO:0043388 83 48 1,000 8,282E-03 0,12337749 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 8,619E-03 0,12761296 ! regulation of action potential GO:0001508 102 50 1,000 8,962E-03 0,13188649 ! negative regulation of immune system process GO:0002683 101 51 1,000 9,31E-03 0,13619687 ! positive regulation of binding GO:0051099 88 52 1,000 9,665E-03 0,1405429 ! amino acid activation GO:0043038 98 52 1,000 9,665E-03 0,13971128 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 1,000 0,0100254 0,14407094 ! synapse organization GO:0050808 102 53 1,000 0,0100254 0,14322842 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01039187 0,14760086 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01039187 0,14674768 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,01039187 0,1459043 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01076422 0,15026848 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 0,01076422 0,14941468 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,0111424 0,15379029 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,0111424 0,15292629 ! regulation of DNA replication GO:0006275 105 56 1,000 0,0111424 0,15207196 ! muscle fiber development GO:0048747 131 57 1,000 0,01152638 0,15643862 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01152638 0,15557431 ! heart morphogenesis GO:0003007 105 57 1,000 0,01152638 0,15471951 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,01191613 0,1590771 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01191613 0,15821255 ! maintenance of location GO:0051235 124 58 1,000 0,01191613 0,15735734 ! establishment of organelle localization GO:0051656 122 59 1,000 0,01231161 0,16170574 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,01271279 0,16608205 ! viral reproductive process GO:0022415 132 62 1,000 0,01353209 0,17584522 ! regulation of mitosis GO:0007088 112 63 1,000 0,01395015 0,1803186 GO:0051783|regulation of nuclear division, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01412802 0,18165657 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01412802 0,18070549 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01412802 0,17976431 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01412802 0,17883289 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01412802 0,17791107 ! neuron fate determination GO:0048664 7 5 0,000 0,01412802 0,17699871 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01412802 0,17609565 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01412802 0,17520177 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01412802 0,17431691 ! polyol transport GO:0015791 12 5 0,000 0,01412802 0,17344095 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01412802 0,17257374 ! response to superoxide GO:0000303 10 5 0,000 0,01412802 0,17171517 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01412802 0,17086509 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01412802 0,17002339 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01412802 0,16918994 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01412802 0,16836463 ! female meiosis GO:0007143 10 5 0,000 0,01412802 0,16754732 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01412802 0,16673791 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01412802 0,16593629 ! hypothalamus development GO:0021854 9 5 0,000 0,01412802 0,16514234 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01412802 0,16435594 ! cobalt ion transport GO:0006824 11 5 0,000 0,01412802 0,16357701 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01412802 0,16280542 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01412802 0,16204107 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01412802 0,16128387 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01412802 0,16053371 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01412802 0,1597905 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01412802 0,15905414 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01412802 0,15832453 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01412802 0,15760159 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01412802 0,15688522 ! transposition GO:0032196 9 5 0,000 0,01412802 0,15617533 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01412802 0,15547184 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01412802 0,15477466 ! negative chemotaxis GO:0050919 16 5 0,000 0,01412802 0,1540837 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01412802 0,15339888 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01412802 0,15272013 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01412802 0,15204735 ! behavioral response to pain GO:0048266 10 5 0,000 0,01412802 0,15138047 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01412802 0,15071942 ! Notch receptor processing GO:0007220 11 5 0,000 0,01412802 0,15006412 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01412802 0,14941449 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01412802 0,14877047 ! micturition GO:0060073 9 5 0,000 0,01412802 0,14813197 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01412802 0,14749892 ! copulation GO:0007620 9 5 0,000 0,01412802 0,14687127 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01412802 0,14624893 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01412802 0,14563185 ! bioluminescence GO:0008218 9 5 0,000 0,01412802 0,14501995 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01412802 0,14441317 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01412802 0,14381145 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01412802 0,14321472 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01412802 0,14262293 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01412802 0,142036 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01412802 0,14145389 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01412802 0,14087652 ! grooming behavior GO:0007625 6 5 0,000 0,01412802 0,14030385 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01412802 0,13973582 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01412802 0,13917237 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01412802 0,13861345 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01412802 0,13805899 ! response to protozoan GO:0001562 13 5 0,000 0,01412802 0,13750896 ! lymph vessel development GO:0001945 10 5 0,000 0,01412802 0,13696329 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01412802 0,13642193 ! endochondral ossification GO:0001958 17 5 0,000 0,01412802 0,13588484 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01412802 0,13535195 ! single strand break repair GO:0000012 8 5 0,000 0,01412802 0,13482324 ! parathyroid gland development GO:0060017 14 5 0,000 0,01412802 0,13429863 ! anagen GO:0042640 7 5 0,000 0,01412802 0,13377809 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01412802 0,13326158 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01412802 0,13274903 ! cytokine secretion GO:0050663 15 5 0,000 0,01412802 0,13224041 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01412802 0,13173568 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01412802 0,13123478 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01412802 0,13073768 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01412802 0,13024433 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01412802 0,12975469 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01412802 0,12926872 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01412802 0,12878637 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01412802 0,12830761 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01412802 0,1278324 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01412802 0,12736069 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01412802 0,12689246 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01412802 0,12642765 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01412802 0,12596623 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01412802 0,12550818 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01412802 0,12505344 ! microvillus organization GO:0032528 8 5 0,000 0,01412802 0,12460198 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01412802 0,12415377 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01412802 0,12370878 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01412802 0,12326696 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01412802 0,12282829 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01412802 0,12239272 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01412802 0,12196024 ! polyol catabolic process GO:0046174 9 5 0,000 0,01412802 0,1215308 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01412802 0,12110438 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01412802 0,12068094 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01412802 0,12026045 ! muscle cell migration GO:0014812 8 5 0,000 0,01412802 0,11984288 ! mitochondrial fission GO:0000266 8 5 0,000 0,01412802 0,11942819 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01412802 0,11901637 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01412802 0,11860738 ! mRNA transcription GO:0009299 10 5 0,000 0,01412802 0,11820119 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01412802 0,11779778 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01412802 0,1173971 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01412802 0,11699915 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01412802 0,11660388 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01412802 0,11621127 ! monocyte activation GO:0042117 10 5 0,000 0,01412802 0,1158213 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01412802 0,11543394 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01412802 0,11504916 ! response to food GO:0032094 6 5 0,000 0,01412802 0,11466694 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01412802 0,11428725 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01412802 0,11391006 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01412802 0,11353536 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01412802 0,11316311 ! forebrain neuron development GO:0021884 13 5 0,000 0,01412802 0,11279329 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01412802 0,11242589 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01412802 0,11206087 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01412802 0,11169821 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01412802 0,1113379 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01412802 0,1109799 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01412802 0,11062419 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01412802 0,11027076 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01412802 0,10991958 ! lipid glycosylation GO:0030259 7 5 0,000 0,01412802 0,10957063 ! nucleobase transport GO:0015851 6 5 0,000 0,01412802 0,10922389 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01412802 0,10887933 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01412802 0,10853694 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01412802 0,1081967 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01412802 0,10785859 ! basic amino acid transport GO:0015802 12 5 0,000 0,01412802 0,10752258 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01412802 0,10718866 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01412802 0,10685681 ! actin nucleation GO:0045010 11 5 0,000 0,01412802 0,106527 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01412802 0,10619923 ! depurination GO:0045007 5 5 0,000 0,01412802 0,10587346 ! depyrimidination GO:0045008 10 5 0,000 0,01412802 0,10554969 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01412802 0,10522789 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01412802 0,10490805 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01412802 0,10459015 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01412802 0,10427416 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01412802 0,10396009 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01412802 0,10364789 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01412802 0,10333757 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01412802 0,1030291 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01412802 0,10272247 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01412802 0,10241765 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01412802 0,10211464 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01412802 0,10181342 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01412802 0,10151397 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01412802 0,10121627 ! response to arsenic GO:0046685 11 5 0,000 0,01412802 0,10092032 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01412802 0,10062609 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01412802 0,10033357 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01412802 0,10004275 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01412802 0,09975361 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01412802 0,09946613 ! response to mercury ion GO:0046689 8 5 0,000 0,01412802 0,09918031 ! response to cadmium ion GO:0046686 7 5 0,000 0,01412802 0,09889613 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01412802 0,09861357 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01412802 0,09833262 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01412802 0,09805326 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01412802 0,09777549 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01412802 0,09749929 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01412802 0,09722464 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01412802 0,09695154 ! decidualization GO:0046697 11 5 0,000 0,01412802 0,09667997 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01412802 0,09640991 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01412802 0,09614136 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01412802 0,0958743 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01412802 0,09560872 ! embryonic cleavage GO:0040016 6 5 0,000 0,01412802 0,09534461 ! peroxisome fission GO:0016559 5 5 0,000 0,01412802 0,09508195 ! histone demethylation GO:0016577 13 5 0,000 0,01412802 0,09482074 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01412802 0,09456095 ! mitotic recombination GO:0006312 9 5 0,000 0,01412802 0,09430259 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01412802 0,09404564 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01412802 0,09379008 ! metaphase plate congression GO:0051310 7 5 0,000 0,01412802 0,0935359 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01412802 0,0932831 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01412802 0,09303167 ! enteric nervous system development GO:0048484 8 5 0,000 0,01412802 0,09278158 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01412802 0,09253284 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01412802 0,09228542 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01412802 0,09203933 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01412802 0,09179454 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01412802 0,09155106 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01412802 0,09130886 ! B cell homeostasis GO:0001782 13 5 0,000 0,01412802 0,09106794 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01412802 0,09082828 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01412802 0,09058989 ! metaphase GO:0051323 11 5 0,000 0,01412802 0,09035274 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01412802 0,09011684 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01412802 0,08988216 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01412802 0,0896487 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01412802 0,08941645 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01412802 0,0891854 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01412802 0,08895554 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01412802 0,08872686 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01412802 0,08849935 ! response to redox state GO:0051775 6 5 0,000 0,01412802 0,08827301 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01412802 0,08804783 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01412802 0,08782379 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01412802 0,08760088 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01412802 0,08737911 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01412802 0,08715846 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01412802 0,08693891 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01412802 0,08672047 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01412802 0,08650313 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01412802 0,08628687 ! striatum development GO:0021756 14 5 0,000 0,01412802 0,08607169 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01412802 0,08585758 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01412802 0,08564454 ! glial cell migration GO:0008347 10 5 0,000 0,01412802 0,08543255 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01412802 0,0852216 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01412802 0,0850117 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01412802 0,08480282 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01412802 0,08459497 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01412802 0,08438814 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01412802 0,08418231 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01412802 0,08397749 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01412802 0,08377366 ! neuroprotection GO:0043526 8 5 0,000 0,01412802 0,08357082 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01412802 0,08336896 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01412802 0,08316807 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01412802 0,08296814 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01412802 0,08276918 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01412802 0,08257117 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01412802 0,0823741 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01412802 0,08217797 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01412802 0,08198277 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01412802 0,0817885 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01412802 0,08159515 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01412802 0,08140271 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01412802 0,08121117 ! spindle assembly GO:0051225 6 5 0,000 0,01412802 0,08102054 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01412802 0,08083079 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01412802 0,08064194 ! protein palmitoylation GO:0018345 12 5 0,000 0,01412802 0,08045396 ! drug metabolic process GO:0017144 7 5 0,000 0,01412802 0,08026686 ! stem cell division GO:0017145 11 5 0,000 0,01412802 0,08008062 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01412802 0,07989525 ! organ regeneration GO:0031100 7 5 0,000 0,01412802 0,07971073 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01412802 0,07952707 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01412802 0,07934425 ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,0148029 0,08294378 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,01567761 0,08764394 ! activation of MAPK activity GO:0000187 124 67 1,000 0,01567761 0,08744384 ! chromosome segregation GO:0007059 127 67 1,000 0,01567761 0,08724465 ! extracellular matrix organization GO:0030198 146 68 1,000 0,01612311 0,08951993 ! viral reproduction GO:0016032 142 68 1,000 0,01612311 0,08931693 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01612311 0,08911486 ! negative regulation of cell size GO:0045792 144 69 1,000 0,016574 0,09140021 ! cellular hormone metabolic process GO:0034754 120 69 1,000 0,016574 0,09119436 ! lung development GO:0030324 165 69 1,000 0,016574 0,09098942 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,016574 0,09078541 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01692982 0,09252693 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01692982 0,0923204 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01692982 0,09211479 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01692982 0,09191009 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01692982 0,09170629 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01692982 0,0915034 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01692982 0,09130141 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01692982 0,09110031 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01692982 0,09090009 ! response to oxygen radical GO:0000305 11 6 0,000 0,01692982 0,09070074 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01692982 0,09050227 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01692982 0,09030467 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01692982 0,09010793 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01692982 0,08991204 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01692982 0,089717 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01692982 0,08952281 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01692982 0,08932946 ! forebrain regionalization GO:0021871 9 6 0,000 0,01692982 0,08913694 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01692982 0,08894524 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01692982 0,08875438 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01692982 0,08856432 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01692982 0,08837508 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01692982 0,08818665 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01692982 0,08799902 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01692982 0,08781218 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01692982 0,08762614 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01692982 0,08744089 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01692982 0,08725641 ! malate metabolic process GO:0006108 13 6 0,000 0,01692982 0,08707271 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01692982 0,08688979 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01692982 0,08670763 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01692982 0,08652623 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01692982 0,08634559 ! protein refolding GO:0042026 15 6 0,000 0,01692982 0,08616571 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01692982 0,08598657 ! opsonization GO:0008228 8 6 0,000 0,01692982 0,08580817 ! mating behavior GO:0007617 7 6 0,000 0,01692982 0,08563052 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01692982 0,08545359 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01692982 0,0852774 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01692982 0,08510193 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01692982 0,08492718 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01692982 0,08475315 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01692982 0,08457983 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01692982 0,08440722 ! toxin metabolic process GO:0009404 11 6 0,000 0,01692982 0,08423531 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01692982 0,0840641 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01692982 0,08389359 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01692982 0,08372376 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01692982 0,08355462 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01692982 0,08338617 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01692982 0,08321839 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01692982 0,08305128 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01692982 0,08288485 ! thymic T cell selection GO:0045061 16 6 0,000 0,01692982 0,08271908 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01692982 0,08255397 ! protein lipoylation GO:0009249 10 6 0,000 0,01692982 0,08238952 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01692982 0,08222572 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01692982 0,08206258 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01692982 0,08190008 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01692982 0,08173822 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01692982 0,081577 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01692982 0,08141641 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01692982 0,08125646 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01692982 0,08109713 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01692982 0,08093843 ! hyperosmotic response GO:0006972 10 6 0,000 0,01692982 0,08078035 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01692982 0,08062288 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01692982 0,08046603 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01692982 0,08030978 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01692982 0,08015414 ! urea metabolic process GO:0019627 7 6 0,000 0,01692982 0,07999911 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01692982 0,07984467 ! neutrophil activation GO:0042119 7 6 0,000 0,01692982 0,07969083 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01692982 0,07953757 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01692982 0,07938491 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01692982 0,07923283 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01692982 0,07908134 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01692982 0,07893042 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01692982 0,07878007 ! neuron apoptosis GO:0051402 15 6 0,000 0,01692982 0,0786303 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01692982 0,0784811 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01692982 0,07833246 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01692982 0,07818438 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01692982 0,07803687 ! carnitine transport GO:0015879 10 6 0,000 0,01692982 0,0778899 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01692982 0,07774349 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01692982 0,07759763 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01692982 0,07745232 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01692982 0,07730755 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01692982 0,07716332 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01692982 0,07701963 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01692982 0,07687647 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01692982 0,07673384 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01692982 0,07659174 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01692982 0,07645016 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01692982 0,07630911 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01692982 0,07616858 ! response to UV-C GO:0010225 14 6 0,000 0,01692982 0,07602856 ! astrocyte development GO:0014002 16 6 0,000 0,01692982 0,07588906 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01692982 0,07575007 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01692982 0,07561159 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01692982 0,07547361 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01692982 0,07533614 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01692982 0,07519916 ! response to copper ion GO:0046688 10 6 0,000 0,01692982 0,07506268 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01692982 0,0749267 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01692982 0,07479121 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01692982 0,07465621 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01692982 0,07452169 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01692982 0,07438766 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01692982 0,07425411 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01692982 0,07412104 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01692982 0,07398844 ! hair follicle maturation GO:0048820 8 6 0,000 0,01692982 0,07385632 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01692982 0,07372467 ! Schwann cell development GO:0014044 15 6 0,000 0,01692982 0,07359349 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01692982 0,07346277 ! response to pheromone GO:0019236 6 6 0,000 0,01692982 0,07333252 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01692982 0,07320272 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01692982 0,07307339 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01692982 0,07294451 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01692982 0,07281609 ! subpallium development GO:0021544 15 6 0,000 0,01692982 0,07268812 ! neural tube patterning GO:0021532 8 6 0,000 0,01692982 0,07256059 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01692982 0,07243352 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01692982 0,07230689 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01692982 0,0721807 ! G2 phase GO:0051319 16 6 0,000 0,01692982 0,07205495 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01692982 0,07192963 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01692982 0,07180475 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01692982 0,07168031 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01692982 0,0715563 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01692982 0,07143271 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01692982 0,07130955 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01692982 0,07118681 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01692982 0,0710645 ! receptor internalization GO:0031623 11 6 0,000 0,01692982 0,07094261 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01692982 0,07082113 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01692982 0,07070007 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01692982 0,07057942 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01692982 0,07045918 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01692982 0,07033935 ! protein deubiquitination GO:0016579 16 6 0,000 0,01692982 0,07021993 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01692982 0,07010091 ! protein destabilization GO:0031648 9 6 0,000 0,01692982 0,0699823 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01692982 0,06986409 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01692982 0,06974627 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01692982 0,06962885 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01692982 0,06951183 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01692982 0,0693952 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01692982 0,06927896 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01692982 0,06916311 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01692982 0,06904764 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01692982 0,06893256 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01692982 0,06881787 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01692982 0,06870355 ! neural plate development GO:0001840 9 6 0,000 0,01692982 0,06858962 ! catecholamine transport GO:0051937 9 6 0,000 0,01692982 0,06847606 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01692982 0,06836287 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01692982 0,06825006 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01692982 0,06813763 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01692982 0,06802556 ! maternal placenta development GO:0001893 12 6 0,000 0,01692982 0,06791386 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01692982 0,06780252 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01692982 0,06769155 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01692982 0,06758095 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01692982 0,0674707 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01692982 0,06736081 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01692982 0,06725128 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01692982 0,06714211 GO:0055081|anion homeostasis, ! respiratory tube development GO:0030323 171 72 1,000 0,01795867 0,07110701 ! respiratory system development GO:0060541 175 74 1,000 0,0189081 0,07474513 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,01939062 0,07652872 ! axon guidance GO:0007411 162 75 1,000 0,01939062 0,07640529 ! tRNA transcription GO:0009304 17 7 0,000 0,01972373 0,0775927 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01972373 0,07746796 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01972373 0,07734361 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01972373 0,07721966 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01972373 0,07709611 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01972373 0,07697295 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01972373 0,07685019 ! sleep GO:0030431 16 7 0,000 0,01972373 0,07672782 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01972373 0,07660583 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01972373 0,07648424 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01972373 0,07636303 ! prostate gland development GO:0030850 14 7 0,000 0,01972373 0,0762422 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01972373 0,07612175 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01972373 0,07600169 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01972373 0,075882 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01972373 0,07576269 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01972373 0,07564375 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01972373 0,07552519 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01972373 0,07540699 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01972373 0,07528917 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01972373 0,07517171 ! glycolipid transport GO:0046836 11 7 0,000 0,01972373 0,07505462 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01972373 0,0749379 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01972373 0,07482154 ! neuron adhesion GO:0007158 14 7 0,000 0,01972373 0,07470553 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01972373 0,07458989 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01972373 0,0744746 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01972373 0,07435967 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01972373 0,0742451 ! mRNA stabilization GO:0048255 18 7 0,000 0,01972373 0,07413088 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01972373 0,074017 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01972373 0,07390348 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01972373 0,0737903 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01972373 0,07367748 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01972373 0,07356499 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01972373 0,07345285 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01972373 0,07334105 ! lipoprotein transport GO:0042953 14 7 0,000 0,01972373 0,07322959 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01972373 0,07311847 ! rhythmic behavior GO:0007622 17 7 0,000 0,01972373 0,07300768 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01972373 0,07289723 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01972373 0,07278711 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01972373 0,07267733 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01972373 0,07256787 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01972373 0,07245875 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01972373 0,07234995 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01972373 0,07224148 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01972373 0,07213334 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01972373 0,07202551 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01972373 0,07191801 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01972373 0,07181083 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01972373 0,07170397 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01972373 0,07159743 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01972373 0,0714912 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01972373 0,07138529 ! spinal cord patterning GO:0021511 14 7 0,000 0,01972373 0,07127969 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01972373 0,0711744 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01972373 0,07106942 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01972373 0,07096476 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01972373 0,0708604 ! adrenal gland development GO:0030325 17 7 0,000 0,01972373 0,07075634 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01972373 0,07065259 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01972373 0,07054915 ! ovulation GO:0030728 10 7 0,000 0,01972373 0,07044601 ! adenohypophysis development GO:0021984 11 7 0,000 0,01972373 0,07034317 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01972373 0,07024063 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01972373 0,07013838 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01972373 0,07003644 ! microtubule nucleation GO:0007020 21 7 0,000 0,01972373 0,06993479 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01972373 0,06983343 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01972373 0,06973237 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01972373 0,0696316 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01972373 0,06953112 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01972373 0,06943093 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01972373 0,06933103 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01972373 0,06923142 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01972373 0,06913209 ! galactose metabolic process GO:0006012 13 7 0,000 0,01972373 0,06903305 ! vesicle fusion GO:0006906 20 7 0,000 0,01972373 0,06893429 ! response to dietary excess GO:0002021 8 7 0,000 0,01972373 0,06883581 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01972373 0,06873762 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01972373 0,0686397 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01972373 0,06854206 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01972373 0,0684447 ! organ growth GO:0035265 15 7 0,000 0,01972373 0,06834762 ! nucleoside transport GO:0015858 11 7 0,000 0,01972373 0,06825081 ! nucleoside salvage GO:0043174 11 7 0,000 0,01972373 0,06815427 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01972373 0,06805801 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01972373 0,06796202 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01972373 0,06786629 ! parturition GO:0007567 16 7 0,000 0,01972373 0,06777084 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01972373 0,06767566 ! rRNA modification GO:0000154 14 7 0,000 0,01972373 0,06758074 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01972373 0,06748609 ! spindle checkpoint GO:0031577 16 7 0,000 0,01972373 0,0673917 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01972373 0,06729758 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01972373 0,06720372 ! monocyte differentiation GO:0030224 16 7 0,000 0,01972373 0,06711012 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01972373 0,06701679 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01972373 0,06692371 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01972373 0,06683089 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01972373 0,06673832 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01972373 0,06664601 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01972373 0,06655396 ! fibrinolysis GO:0042730 11 7 0,000 0,01972373 0,06646216 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01972373 0,06637062 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01972373 0,06627932 ! eating behavior GO:0042755 8 7 0,000 0,01972373 0,06618828 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01972373 0,06609749 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01972373 0,06600694 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01972373 0,06591665 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01972373 0,0658266 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01972373 0,06573679 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01972373 0,06564723 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01972373 0,06555792 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01972373 0,06546884 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01972373 0,06538001 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01972373 0,06529142 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01972373 0,06520307 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01972373 0,06511496 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01972373 0,06502708 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01972373 0,06493945 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01972373 0,06485204 ! histone ubiquitination GO:0016574 9 7 0,000 0,01972373 0,06476488 ! regulation of meiosis GO:0040020 12 7 0,000 0,01972373 0,06467794 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01972373 0,06459125 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01972373 0,06450478 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01972373 0,06441854 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01972373 0,06433254 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01972373 0,06424676 ! transcription termination GO:0006353 14 7 0,000 0,01972373 0,06416121 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01972373 0,06407589 ! anaphase GO:0051322 18 7 0,000 0,01972373 0,0639908 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01972373 0,06390593 ! axonal fasciculation GO:0007413 19 7 0,000 0,01972373 0,06382128 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01972373 0,06373686 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01972373 0,06365267 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01972373 0,06356869 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01972373 0,06348494 ! diuresis GO:0030146 12 7 0,000 0,01972373 0,06340141 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01972373 0,06331809 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01972373 0,063235 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01972373 0,06315212 ! antibiotic transport GO:0042891 9 7 0,000 0,01972373 0,06306946 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01972373 0,06298702 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01972373 0,06290479 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01972373 0,06282278 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01972373 0,06274098 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01972373 0,06265939 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01972373 0,06257801 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01972373 0,06249685 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01972373 0,06241589 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01972373 0,06233515 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01972373 0,06225461 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01972373 0,06217428 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01972373 0,06209416 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01972373 0,06201425 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01972373 0,06193454 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01972373 0,06185503 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01972373 0,06177573 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01972373 0,06169663 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01972373 0,06161774 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01972373 0,06153904 ! muscle adaptation GO:0043500 13 7 0,000 0,01972373 0,06146055 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01972373 0,06138225 ! retina homeostasis GO:0001895 12 7 0,000 0,01972373 0,06130416 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01972373 0,06122626 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01972373 0,06114856 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01972373 0,06107106 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01972373 0,06099376 ! regulation of blood pressure GO:0008217 134 76 1,000 0,01987829 0,06139401 ! neurotransmitter transport GO:0006836 142 77 1,000 0,02037108 0,06283656 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,02037108 0,06275732 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,02086897 0,06421019 ! steroid biosynthetic process GO:0006694 146 79 1,000 0,02137191 0,06567494 ! protein oligomerization GO:0051259 149 79 1,000 0,02137191 0,06559243 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,02137191 0,06551014 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,02187988 0,06698314 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,02187988 0,06689931 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,02187988 0,06681568 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,02239284 0,06829677 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02250978 0,06856782 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02250978 0,06848243 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02250978 0,06839725 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02250978 0,06831229 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02250978 0,06822753 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02250978 0,06814299 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02250978 0,06805865 ! male meiosis GO:0007140 9 8 0,000 0,02250978 0,06797453 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02250978 0,06789061 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02250978 0,0678069 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02250978 0,06772339 ! meiotic prophase I GO:0007128 14 8 0,000 0,02250978 0,06764009 ! response to zinc ion GO:0010043 12 8 0,000 0,02250978 0,06755699 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02250978 0,0674741 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02250978 0,06739141 ! oligopeptide transport GO:0006857 16 8 0,000 0,02250978 0,06730893 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02250978 0,06722664 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02250978 0,06714456 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02250978 0,06706267 ! signal peptide processing GO:0006465 12 8 0,000 0,02250978 0,06698099 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02250978 0,0668995 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02250978 0,06681822 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02250978 0,06673713 ! succinate metabolic process GO:0006105 17 8 0,000 0,02250978 0,06665623 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02250978 0,06657554 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02250978 0,06649503 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02250978 0,06641472 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02250978 0,06633461 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02250978 0,06625469 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02250978 0,06617496 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02250978 0,06609542 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02250978 0,06601608 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02250978 0,06593692 ! reflex GO:0060004 17 8 0,000 0,02250978 0,06585795 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02250978 0,06577918 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02250978 0,06570059 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02250978 0,06562219 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02250978 0,06554397 ! pigment granule organization GO:0048753 17 8 0,000 0,02250978 0,06546594 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02250978 0,0653881 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02250978 0,06531044 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02250978 0,06523297 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02250978 0,06515568 ! histidine catabolic process GO:0006548 10 8 0,000 0,02250978 0,06507857 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02250978 0,06500165 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02250978 0,0649249 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02250978 0,06484834 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,02250978 0,06477196 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02250978 0,06469576 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02250978 0,06461973 ! melanin metabolic process GO:0006582 17 8 0,000 0,02250978 0,06454389 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02250978 0,06446822 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02250978 0,06439273 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02250978 0,06431742 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02250978 0,06424228 ! macrophage activation GO:0042116 13 8 0,000 0,02250978 0,06416732 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02250978 0,06409253 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02250978 0,06401792 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02250978 0,06394348 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02250978 0,06386921 ! purine salvage GO:0043101 12 8 0,000 0,02250978 0,06379512 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02250978 0,0637212 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02250978 0,06364744 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02250978 0,06357386 ! osteoblast development GO:0002076 17 8 0,000 0,02250978 0,06350045 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02250978 0,06342721 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02250978 0,06335414 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02250978 0,06328123 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02250978 0,0632085 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02250978 0,06313593 ! response to UV-B GO:0010224 17 8 0,000 0,02250978 0,06306352 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02250978 0,06299129 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02250978 0,06291921 ! intermediate filament organization GO:0045109 12 8 0,000 0,02250978 0,06284731 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02250978 0,06277556 ! cellular extravasation GO:0045123 13 8 0,000 0,02250978 0,06270398 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02250978 0,06263256 ! response to antibiotic GO:0046677 11 8 0,000 0,02250978 0,06256131 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02250978 0,06249022 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02250978 0,06241929 ! DNA topological change GO:0006265 12 8 0,000 0,02250978 0,06234852 ! response to tropane GO:0014073 15 8 0,000 0,02250978 0,06227791 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,02250978 0,06220746 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02250978 0,06213717 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02250978 0,06206703 ! mast cell activation GO:0045576 14 8 0,000 0,02250978 0,06199706 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02250978 0,06192724 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02250978 0,06185758 ! gas homeostasis GO:0033483 14 8 0,000 0,02250978 0,06178808 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02250978 0,06171873 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02250978 0,06164954 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02250978 0,06158051 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02250978 0,06151162 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02250978 0,0614429 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02250978 0,06137432 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02250978 0,0613059 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02250978 0,06123763 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02250978 0,06116951 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02250978 0,06110155 ! response to tumor cell GO:0002347 16 8 0,000 0,02250978 0,06103373 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02250978 0,06096607 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02250978 0,06089855 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02250978 0,06083119 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02250978 0,06076397 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02250978 0,0606969 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02250978 0,06062998 ! hormone catabolic process GO:0042447 17 8 0,000 0,02250978 0,06056321 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02250978 0,06049658 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02250978 0,0604301 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02250978 0,06036377 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02250978 0,06029758 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02250978 0,06023154 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02250978 0,06016564 ! adult feeding behavior GO:0008343 10 8 0,000 0,02250978 0,06009988 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02250978 0,06003427 ! ATP catabolic process GO:0006200 11 8 0,000 0,02250978 0,0599688 ! blastocyst growth GO:0001832 19 8 0,000 0,02250978 0,05990348 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02250978 0,05983829 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02250978 0,05977325 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02250978 0,05970835 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02250978 0,05964359 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02250978 0,05957897 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02250978 0,05951449 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02250978 0,05945015 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02250978 0,05938595 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02250978 0,05932189 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02250978 0,05925797 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02250978 0,05919418 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02250978 0,05913053 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02250978 0,05906702 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02250978 0,05900364 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02250978 0,0589404 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02250978 0,05887729 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02250978 0,05881432 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02250978 0,05875149 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02250978 0,05868879 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02250978 0,05862622 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,02343362 0,06096735 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,02343362 0,06090249 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of growth GO:0045926 168 85 1,000 0,024494 0,06359069 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,024494 0,06352318 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,02503146 0,0648482 GO:0002696|positive regulation of leukocyte activation, ! axon extension GO:0048675 16 9 0,000 0,02528799 0,06544339 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02528799 0,06537414 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02528799 0,06530503 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02528799 0,06523607 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02528799 0,06516726 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02528799 0,06509859 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02528799 0,06503007 ! reproductive behavior GO:0019098 22 9 0,000 0,02528799 0,06496168 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02528799 0,06489345 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02528799 0,06482535 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02528799 0,0647574 ! UTP metabolic process GO:0046051 10 9 0,000 0,02528799 0,06468959 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02528799 0,06462193 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02528799 0,0645544 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02528799 0,06448702 ! artery development GO:0060840 25 9 0,000 0,02528799 0,06441977 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02528799 0,06435267 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02528799 0,0642857 ! equilibrioception GO:0050957 20 9 0,000 0,02528799 0,06421888 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02528799 0,06415219 ! chemosensory behavior GO:0007635 21 9 0,000 0,02528799 0,06408565 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02528799 0,06401924 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02528799 0,06395296 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02528799 0,06388683 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02528799 0,06382083 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02528799 0,06375497 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02528799 0,06368924 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02528799 0,06362365 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02528799 0,06355819 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02528799 0,06349287 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02528799 0,06342768 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02528799 0,06336263 ! protein targeting to ER GO:0045047 25 9 0,000 0,02528799 0,06329771 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02528799 0,06323292 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02528799 0,06316826 ! T cell selection GO:0045058 27 9 0,000 0,02528799 0,06310374 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02528799 0,06303935 ! glycine catabolic process GO:0006546 15 9 0,000 0,02528799 0,06297509 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02528799 0,06291096 ! endosome organization GO:0007032 20 9 0,000 0,02528799 0,06284696 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02528799 0,06278309 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02528799 0,06271935 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02528799 0,06265574 ! mannose metabolic process GO:0006013 13 9 0,000 0,02528799 0,06259226 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02528799 0,06252891 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02528799 0,06246568 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02528799 0,06240259 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02528799 0,06233962 ! receptor clustering GO:0043113 20 9 0,000 0,02528799 0,06227678 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02528799 0,06221406 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02528799 0,06215147 ! retinol metabolic process GO:0042572 20 9 0,000 0,02528799 0,06208901 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02528799 0,06202667 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02528799 0,06196446 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02528799 0,06190237 ! macrophage differentiation GO:0030225 15 9 0,000 0,02528799 0,0618404 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02528799 0,06177856 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02528799 0,06171685 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02528799 0,06165525 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02528799 0,06159378 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02528799 0,06153243 ! response to amine stimulus GO:0014075 13 9 0,000 0,02528799 0,06147121 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02528799 0,0614101 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02528799 0,06134912 ! erythrocyte development GO:0048821 17 9 0,000 0,02528799 0,06128826 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02528799 0,06122751 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02528799 0,06116689 ! renal water homeostasis GO:0003091 15 9 0,000 0,02528799 0,06110639 ! postreplication repair GO:0006301 25 9 0,000 0,02528799 0,06104601 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02528799 0,06098575 ! icosanoid secretion GO:0032309 15 9 0,000 0,02528799 0,0609256 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02528799 0,06086558 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02528799 0,06080567 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02528799 0,06074588 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02528799 0,06068621 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02528799 0,06062666 ! sterol catabolic process GO:0016127 14 9 0,000 0,02528799 0,06056722 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02528799 0,0605079 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02528799 0,06044869 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02528799 0,0603896 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02528799 0,06033063 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02528799 0,06027177 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02528799 0,06021302 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02528799 0,06015439 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02528799 0,06009588 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02528799 0,06003748 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02528799 0,05997919 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02528799 0,05992101 ! purine base metabolic process GO:0006144 25 9 0,000 0,02528799 0,05986295 ! pigment granule transport GO:0051904 17 9 0,000 0,02528799 0,059805 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02528799 0,05974716 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02528799 0,05968943 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02528799 0,05963182 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02528799 0,05957431 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02528799 0,05951692 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02528799 0,05945964 ! nucleosome assembly GO:0006334 126 87 1,000 0,02557372 0,06007365 ! chromatin assembly GO:0031497 128 88 1,000 0,02612076 0,06129972 ! regulation of DNA binding GO:0051101 167 89 1,000 0,02667253 0,06253455 ! regulation of neurological system process GO:0031644 175 89 1,000 0,02667253 0,06247459 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,02722902 0,06371696 ! ossification GO:0001503 205 91 1,000 0,0277902 0,0649679 ! gland development GO:0048732 220 91 1,000 0,0277902 0,06490578 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02805838 0,06546956 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02805838 0,06540709 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02805838 0,06534474 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02805838 0,06528251 ! associative learning GO:0008306 21 10 0,000 0,02805838 0,06522039 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02805838 0,0651584 ! phosphate transport GO:0006817 24 10 0,000 0,02805838 0,06509652 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02805838 0,06503476 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02805838 0,06497311 ! CTP metabolic process GO:0046036 11 10 0,000 0,02805838 0,06491158 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02805838 0,06485017 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02805838 0,06478888 ! GTP metabolic process GO:0046039 11 10 0,000 0,02805838 0,0647277 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02805838 0,06466663 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02805838 0,06460569 ! social behavior GO:0035176 29 10 0,000 0,02805838 0,06454485 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02805838 0,06448413 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02805838 0,06442353 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02805838 0,06436303 ! androgen metabolic process GO:0008209 17 10 0,000 0,02805838 0,06430266 ! phospholipid efflux GO:0033700 19 10 0,000 0,02805838 0,06424239 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02805838 0,06418224 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02805838 0,0641222 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02805838 0,06406227 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02805838 0,06400246 ! lung alveolus development GO:0048286 26 10 0,000 0,02805838 0,06394275 ! pathogenesis GO:0009405 17 10 0,000 0,02805838 0,06388316 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02805838 0,06382368 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02805838 0,06376431 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02805838 0,06370505 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02805838 0,0636459 ! endoderm development GO:0007492 18 10 0,000 0,02805838 0,06358686 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02805838 0,06352793 ! arginine catabolic process GO:0006527 17 10 0,000 0,02805838 0,0634691 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02805838 0,06341039 ! proline metabolic process GO:0006560 13 10 0,000 0,02805838 0,06335179 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02805838 0,06329329 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02805838 0,0632349 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02805838 0,06317662 ! V(D)J recombination GO:0033151 34 10 0,000 0,02805838 0,06311845 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02805838 0,06306038 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02805838 0,06300242 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02805838 0,06294457 ! B cell proliferation GO:0042100 19 10 0,000 0,02805838 0,06288682 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02805838 0,06282918 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02805838 0,06277164 ! multicellular organism growth GO:0035264 19 10 0,000 0,02805838 0,06271421 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02805838 0,06265688 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02805838 0,06259966 ! ruffle organization GO:0031529 17 10 0,000 0,02805838 0,06254255 ! epithelial cell development GO:0002064 21 10 0,000 0,02805838 0,06248553 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02805838 0,06242863 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02805838 0,06237182 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02805838 0,06231512 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02805838 0,06225852 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02805838 0,06220203 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02805838 0,06214563 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02805838 0,06208934 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02805838 0,06203315 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02805838 0,06197706 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02805838 0,06192108 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02805838 0,06186519 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02805838 0,06180941 ! segment specification GO:0007379 15 10 0,000 0,02805838 0,06175372 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02805838 0,06169814 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02805838 0,06164265 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02805838 0,06158727 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02805838 0,06153199 ! response to dsRNA GO:0043331 23 10 0,000 0,02805838 0,0614768 ! DNA ligation GO:0006266 18 10 0,000 0,02805838 0,06142171 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02805838 0,06136673 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02805838 0,06131184 ! melanosome localization GO:0032400 16 10 0,000 0,02805838 0,06125704 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02805838 0,06120235 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02805838 0,06114775 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02805838 0,06109325 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02805838 0,06103885 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02805838 0,06098455 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02805838 0,06093034 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02805838 0,06087623 ! protein sumoylation GO:0016925 17 10 0,000 0,02805838 0,06082221 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02805838 0,06076829 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02805838 0,06071447 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02805838 0,06066074 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02805838 0,0606071 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02805838 0,06055356 ! salivary gland development GO:0007431 28 10 0,000 0,02805838 0,06050012 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02805838 0,06044677 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02805838 0,06039351 ! midbrain development GO:0030901 14 10 0,000 0,02805838 0,06034034 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02805838 0,06028728 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02805838 0,0602343 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02805838 0,06018142 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02805838 0,06012862 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02805838 0,06007593 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02805838 0,06002332 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02805838 0,05997081 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02805838 0,05991838 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02805838 0,05986605 ! detection of calcium ion GO:0005513 24 10 0,000 0,02805838 0,05981381 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02805838 0,05976167 ! blastocyst formation GO:0001825 18 10 0,000 0,02805838 0,05970961 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02805838 0,05965764 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02805838 0,05960577 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02805838 0,05955398 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02805838 0,05950228 ! response to nicotine GO:0035094 20 10 0,000 0,02805838 0,05945068 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02805838 0,05939916 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02805838 0,05934773 ! bone development GO:0060348 206 92 1,000 0,02835602 0,05992539 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,02835602 0,0598736 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,02835602 0,0598219 ! female pregnancy GO:0007565 166 94 1,000 0,0295015 0,06218478 ! regulation of membrane potential GO:0042391 179 94 1,000 0,0295015 0,06213117 ! nucleosome organization GO:0034728 143 95 1,000 0,03008109 0,06329725 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,03008109 0,06324277 ! regulation of T cell activation GO:0050863 175 96 1,000 0,03066521 0,06441541 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03082098 0,06468699 ! respiratory burst GO:0045730 17 11 0,000 0,03082098 0,06463146 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03082098 0,06457603 ! neuron fate specification GO:0048665 18 11 0,000 0,03082098 0,0645207 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03082098 0,06446546 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03082098 0,06441031 ! thyroid gland development GO:0030878 26 11 0,000 0,03082098 0,06435526 ! synapsis GO:0007129 14 11 0,000 0,03082098 0,0643003 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03082098 0,06424544 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03082098 0,06419067 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,03082098 0,06413599 ! response to pain GO:0048265 27 11 0,000 0,03082098 0,06408141 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03082098 0,06402692 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03082098 0,06397252 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03082098 0,06391821 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03082098 0,063864 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03082098 0,06380988 ! bone resorption GO:0045453 16 11 0,000 0,03082098 0,06375585 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03082098 0,06370191 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,03082098 0,06364806 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03082098 0,0635943 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03082098 0,06354064 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03082098 0,06348706 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03082098 0,06343358 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03082098 0,06338018 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03082098 0,06332688 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03082098 0,06327366 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03082098 0,06322053 ! UV protection GO:0009650 20 11 0,000 0,03082098 0,0631675 ! adult heart development GO:0007512 16 11 0,000 0,03082098 0,06311455 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03082098 0,06306169 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03082098 0,06300892 ! macroautophagy GO:0016236 19 11 0,000 0,03082098 0,06295623 ! temperature homeostasis GO:0001659 18 11 0,000 0,03082098 0,06290364 ! behavioral fear response GO:0001662 27 11 0,000 0,03082098 0,06285113 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03082098 0,06279871 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03082098 0,06274638 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03082098 0,06269413 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03082098 0,06264198 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03082098 0,0625899 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03082098 0,06253792 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03082098 0,06248602 ! regulation of organ growth GO:0046620 14 11 0,000 0,03082098 0,06243421 ! pigment granule localization GO:0051875 20 11 0,000 0,03082098 0,06238248 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03082098 0,06233084 ! vasoconstriction GO:0042310 20 11 0,000 0,03082098 0,06227928 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03082098 0,06222781 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03082098 0,06217643 ! embryonic axis specification GO:0000578 19 11 0,000 0,03082098 0,06212513 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03082098 0,06207391 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03082098 0,06202278 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03082098 0,06197173 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03082098 0,06192077 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03082098 0,06186989 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03082098 0,06181909 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03082098 0,06176838 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03082098 0,06171775 ! prophase GO:0051324 17 11 0,000 0,03082098 0,0616672 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03082098 0,06161674 ! nucleosome positioning GO:0016584 15 11 0,000 0,03082098 0,06156636 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03082098 0,06151606 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03082098 0,06146584 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03082098 0,06141571 ! apical protein localization GO:0045176 18 11 0,000 0,03082098 0,06136565 ! acid secretion GO:0046717 20 11 0,000 0,03082098 0,06131568 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03082098 0,06126579 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03082098 0,06121598 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03082098 0,06116625 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03082098 0,0611166 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03082098 0,06106704 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03082098 0,06101755 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03082098 0,06096814 ! cholesterol efflux GO:0033344 21 11 0,000 0,03082098 0,06091881 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03082098 0,06086957 ! oocyte development GO:0048599 20 11 0,000 0,03082098 0,0608204 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03082098 0,06077131 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03082098 0,0607223 ! embryonic gut development GO:0048566 19 11 0,000 0,03082098 0,06067337 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03082098 0,06062452 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03082098 0,06057575 ! activation of innate immune response GO:0002218 16 11 0,000 0,03082098 0,06052705 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03082098 0,06047844 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03082098 0,0604299 ! lysogeny GO:0030069 22 11 0,000 0,03082098 0,06038144 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03082098 0,06033306 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03082098 0,06028475 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03082098 0,06023652 ! nucleus localization GO:0051647 22 11 0,000 0,03082098 0,06018837 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,03125384 0,06098492 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,03304641 0,06443127 GO:0060538|skeletal muscle organ development, ! hormone metabolic process GO:0042445 171 100 1,000 0,03304641 0,06437989 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0335758 0,06535911 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0335758 0,06530707 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0335758 0,06525512 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0335758 0,06520325 ! protein complex disassembly GO:0043241 28 12 0,000 0,0335758 0,06515146 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0335758 0,06509975 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0335758 0,06504812 ! hippocampus development GO:0021766 29 12 0,000 0,0335758 0,06499658 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0335758 0,06494512 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0335758 0,06489374 ! T cell proliferation GO:0042098 32 12 0,000 0,0335758 0,06484244 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0335758 0,06479122 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0335758 0,06474008 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0335758 0,06468903 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0335758 0,06463805 ! drug transport GO:0015893 16 12 0,000 0,0335758 0,06458715 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0335758 0,06453634 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0335758 0,0644856 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0335758 0,06443494 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0335758 0,06438437 ! focal adhesion formation GO:0048041 37 12 0,000 0,0335758 0,06433387 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0335758 0,06428345 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0335758 0,06423311 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0335758 0,06418285 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0335758 0,06413267 ! lipid digestion GO:0044241 21 12 0,000 0,0335758 0,06408257 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0335758 0,06403254 ! entry into host cell GO:0030260 34 12 0,000 0,0335758 0,06398259 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0335758 0,06393272 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0335758 0,06388293 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0335758 0,06383322 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0335758 0,06378358 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0335758 0,06373402 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0335758 0,06368454 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0335758 0,06363513 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0335758 0,0635858 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0335758 0,06353655 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0335758 0,06348737 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0335758 0,06343827 ! cranial nerve development GO:0021545 23 12 0,000 0,0335758 0,06338925 ! fucose catabolic process GO:0019317 25 12 0,000 0,0335758 0,0633403 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0335758 0,06329142 ! histone acetylation GO:0016573 27 12 0,000 0,0335758 0,06324262 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0335758 0,0631939 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0335758 0,06314525 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0335758 0,06309668 ! zymogen activation GO:0031638 18 12 0,000 0,0335758 0,06304818 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0335758 0,06299976 ! T cell homeostasis GO:0043029 28 12 0,000 0,0335758 0,06295141 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0335758 0,06290313 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0335758 0,06285493 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0335758 0,0628068 ! oocyte differentiation GO:0009994 21 12 0,000 0,0335758 0,06275875 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0335758 0,06271077 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0335758 0,06266286 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0335758 0,06261503 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0335758 0,06256727 ! defense response to fungus GO:0050832 15 12 0,000 0,0335758 0,06251958 ! embryonic placenta development GO:0001892 21 12 0,000 0,0335758 0,06247196 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0335758 0,06242442 ! response to cold GO:0009409 17 12 0,000 0,0335758 0,06237695 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0335758 0,06232955 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0335758 0,06228222 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03632287 0,06732684 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03632287 0,06727579 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03632287 0,06722483 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03632287 0,06717394 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03632287 0,06712313 ! peroxisomal transport GO:0043574 28 13 0,000 0,03632287 0,06707239 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03632287 0,06702173 ! cartilage condensation GO:0001502 22 13 0,000 0,03632287 0,06697115 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03632287 0,06692064 ! organelle fusion GO:0048284 36 13 0,000 0,03632287 0,06687021 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03632287 0,06681986 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03632287 0,06676958 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03632287 0,06671938 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03632287 0,06666925 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03632287 0,0666192 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03632287 0,06656922 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03632287 0,06651932 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03632287 0,06646949 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03632287 0,06641974 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03632287 0,06637006 ! methionine metabolic process GO:0006555 31 13 0,000 0,03632287 0,06632046 ! plasma membrane organization GO:0007009 27 13 0,000 0,03632287 0,06627093 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03632287 0,06622147 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03632287 0,06617209 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03632287 0,06612278 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03632287 0,06607355 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03632287 0,06602438 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03632287 0,0659753 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,03632287 0,06592628 ! exocrine system development GO:0035272 34 13 0,000 0,03632287 0,06587734 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03632287 0,06582847 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03632287 0,06577967 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03632287 0,06573094 ! L-glutamate transport GO:0015813 30 13 0,000 0,03632287 0,06568229 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03632287 0,06563371 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03632287 0,0655852 ! protein homotetramerization GO:0051289 24 13 0,000 0,03632287 0,06553676 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03632287 0,06548839 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03632287 0,0654401 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03632287 0,06539187 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03632287 0,06534372 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03632287 0,06529564 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03632287 0,06524763 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03632287 0,06519969 ! histone methylation GO:0016571 29 13 0,000 0,03632287 0,06515182 ! chromatin silencing GO:0006342 29 13 0,000 0,03632287 0,06510402 ! gland morphogenesis GO:0022612 31 13 0,000 0,03632287 0,06505629 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03632287 0,06500863 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03632287 0,06496103 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03632287 0,06491351 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03632287 0,06486606 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03632287 0,06481868 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03632287 0,06477137 ! spleen development GO:0048536 24 13 0,000 0,03632287 0,06472412 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03632287 0,06467695 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03632287 0,06462984 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03632287 0,0645828 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03632287 0,06453584 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03632287 0,06448893 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03632287 0,0644421 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03632287 0,06439534 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03632287 0,06434864 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03632287 0,06430201 ! insulin secretion GO:0030073 24 13 0,000 0,03632287 0,06425545 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03632287 0,06420895 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03632287 0,06416253 ! acrosome reaction GO:0007340 19 13 0,000 0,03632287 0,06411617 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03632287 0,06406987 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03632287 0,06402365 ! rRNA transcription GO:0009303 28 14 0,000 0,03906221 0,06880243 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03906221 0,06875286 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03906221 0,06870337 ! water transport GO:0006833 21 14 0,000 0,03906221 0,06865394 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03906221 0,06860458 ! non-recombinational repair GO:0000726 29 14 0,000 0,03906221 0,0685553 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03906221 0,06850608 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03906221 0,06845694 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03906221 0,06840787 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03906221 0,06835886 ! lipid localization GO:0010876 32 14 0,000 0,03906221 0,06830993 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03906221 0,06826107 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03906221 0,06821228 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03906221 0,06816355 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03906221 0,0681149 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03906221 0,06806632 ! arginine metabolic process GO:0006525 21 14 0,000 0,03906221 0,0680178 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03906221 0,06796935 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03906221 0,06792098 ! regulation of heart rate GO:0002027 25 14 0,000 0,03906221 0,06787267 ! fear response GO:0042596 34 14 0,000 0,03906221 0,06782443 ! organic alcohol transport GO:0015850 29 14 0,000 0,03906221 0,06777626 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03906221 0,06772816 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03906221 0,06768012 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03906221 0,06763216 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03906221 0,06758426 ! bone mineralization GO:0030282 18 14 0,000 0,03906221 0,06753643 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03906221 0,06748867 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03906221 0,06744097 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03906221 0,06739334 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03906221 0,06734578 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03906221 0,06729829 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03906221 0,06725086 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03906221 0,0672035 ! ribosome assembly GO:0042255 18 14 0,000 0,03906221 0,06715621 ! cerebellum development GO:0021549 23 14 0,000 0,03906221 0,06710898 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03906221 0,06706182 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03906221 0,06701473 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03906221 0,0669677 ! response to gamma radiation GO:0010332 30 14 0,000 0,03906221 0,06692074 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03906221 0,06687384 ! NADP metabolic process GO:0006739 24 14 0,000 0,03906221 0,06682701 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03906221 0,06678025 ! oxygen transport GO:0015671 22 14 0,000 0,03906221 0,06673355 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03906221 0,06668691 ! male genitalia development GO:0030539 26 14 0,000 0,03906221 0,06664035 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03906221 0,06659384 ! regulation of axon extension GO:0030516 43 14 0,000 0,03906221 0,0665474 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03906221 0,06650103 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03906221 0,06645472 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03906221 0,06640847 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04179384 0,07100302 ! lactation GO:0007595 30 15 0,000 0,04179384 0,07095368 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,04179384 0,0709044 ! reproductive cellular process GO:0048610 22 15 0,000 0,04179384 0,0708552 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04179384 0,07080606 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04179384 0,07075699 ! superoxide anion generation GO:0042554 22 15 0,000 0,04179384 0,07070799 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04179384 0,07065906 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04179384 0,07061019 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04179384 0,0705614 ! copper ion transport GO:0006825 22 15 0,000 0,04179384 0,07051267 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04179384 0,070464 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04179384 0,07041541 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04179384 0,07036688 ! sulfate transport GO:0008272 27 15 0,000 0,04179384 0,07031842 ! response to cAMP GO:0051591 25 15 0,000 0,04179384 0,07027002 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04179384 0,07022169 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04179384 0,07017343 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04179384 0,07012523 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04179384 0,0700771 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04179384 0,07002904 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04179384 0,06998104 ! vesicle coating GO:0006901 38 15 0,000 0,04179384 0,06993311 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,04179384 0,06988524 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,04179384 0,06983744 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,04179384 0,06978971 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04179384 0,06974204 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04179384 0,06969443 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,04179384 0,06964689 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04179384 0,06959941 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04179384 0,069552 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04179384 0,06950466 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04179384 0,06945737 ! histone deacetylation GO:0016575 24 15 0,000 0,04179384 0,06941016 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04179384 0,069363 ! water homeostasis GO:0030104 28 15 0,000 0,04179384 0,06931591 ! cofactor transport GO:0051181 30 15 0,000 0,04179384 0,06926889 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04179384 0,06922193 ! muscle maintenance GO:0046716 26 15 0,000 0,04179384 0,06917503 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04179384 0,06912819 ! intestinal absorption GO:0050892 31 15 0,000 0,04179384 0,06908142 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04179384 0,06903471 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04179384 0,06898807 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04179384 0,06894149 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,04179384 0,06889497 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04179384 0,06884851 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04179384 0,06880212 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04179384 0,06875578 ! actin filament polymerization GO:0030041 27 15 0,000 0,04179384 0,06870952 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04179384 0,06866331 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04451777 0,07308933 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04451777 0,07304024 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04451777 0,07299122 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04451777 0,07294227 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04451777 0,07289338 ! bone remodeling GO:0046849 28 16 0,000 0,04451777 0,07284456 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04451777 0,0727958 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04451777 0,07274711 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04451777 0,07269848 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04451777 0,07264991 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04451777 0,07260142 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04451777 0,07255298 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04451777 0,07250461 ! startle response GO:0001964 28 16 0,000 0,04451777 0,07245631 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04451777 0,07240807 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04451777 0,07235989 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04451777 0,07231178 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04451777 0,07226374 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04451777 0,07221575 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04451777 0,07216783 ! pituitary gland development GO:0021983 30 16 0,000 0,04451777 0,07211997 ! response to osmotic stress GO:0006970 27 16 0,000 0,04451777 0,07207218 ! lysosomal transport GO:0007041 31 16 0,000 0,04451777 0,07202445 ! fructose metabolic process GO:0006000 25 16 0,000 0,04451777 0,07197678 ! L-amino acid transport GO:0015807 33 16 0,000 0,04451777 0,07192918 ! stem cell development GO:0048864 46 16 0,000 0,04451777 0,07188164 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04451777 0,07183416 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04451777 0,07178675 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04451777 0,07173939 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04451777 0,0716921 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04451777 0,07164488 ! axon cargo transport GO:0008088 46 16 0,000 0,04451777 0,07159771 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04451777 0,07155061 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04451777 0,07150356 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04451777 0,07145658 ! DNA replication initiation GO:0006270 28 16 0,000 0,04451777 0,07140967 ! neuron recognition GO:0008038 40 16 0,000 0,04451777 0,07136281 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04451777 0,07131601 ! tissue regeneration GO:0042246 27 16 0,000 0,04451777 0,07126928 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04451777 0,07122261 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04451777 0,071176 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04451777 0,07112945 ! biomineral formation GO:0031214 22 16 0,000 0,04451777 0,07108296 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04451777 0,07103653 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04451777 0,07099016 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04451777 0,07094385 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04451777 0,0708976 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04451777 0,07085142 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04451777 0,07080529 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04451777 0,07075922 ! peptide hormone processing GO:0016486 27 16 0,000 0,04451777 0,07071321 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04723405 0,07497906 ! metencephalon development GO:0022037 32 17 0,000 0,04723405 0,07493037 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04723405 0,07488175 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04723405 0,07483319 ! signal complex assembly GO:0007172 47 17 0,000 0,04723405 0,07478469 ! filopodium assembly GO:0046847 42 17 0,000 0,04723405 0,07473625 ! endothelial cell migration GO:0043542 31 17 0,000 0,04723405 0,07468788 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04723405 0,07463957 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04723405 0,07459132 ! glial cell development GO:0021782 28 17 0,000 0,04723405 0,07454314 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04723405 0,07449501 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04723405 0,07444695 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04723405 0,07439895 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04723405 0,07435101 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04723405 0,07430314 ! myoblast differentiation GO:0045445 50 17 0,000 0,04723405 0,07425532 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04723405 0,07420757 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04723405 0,07415988 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04723405 0,07411225 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04723405 0,07406468 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04723405 0,07401717 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04723405 0,07396973 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,04723405 0,07392234 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,04723405 0,07387502 ! membrane budding GO:0006900 42 17 0,000 0,04723405 0,07382775 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04723405 0,07378055 ! regulation of protein binding GO:0043393 33 17 0,000 0,04723405 0,0737334 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04723405 0,07368632 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04723405 0,07363929 ! genitalia development GO:0048806 32 17 0,000 0,04723405 0,07359233 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04723405 0,07354543 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04723405 0,07349858 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04723405 0,0734518 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04723405 0,07340507 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,04723405 0,07335841 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04723405 0,0733118 ! steroid catabolic process GO:0006706 34 17 0,000 0,04723405 0,07326525 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04723405 0,07321877 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04723405 0,07317234 ! gas transport GO:0015669 26 17 0,000 0,04723405 0,07312597 ! organic cation transport GO:0015695 32 17 0,000 0,04723405 0,07307965 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04723405 0,0730334 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04723405 0,07298721 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04723405 0,07294107 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04994267 0,07707514 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04994267 0,07702648 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04994267 0,07697789 ! limbic system development GO:0021761 40 18 0,000 0,04994267 0,07692935 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04994267 0,07688087 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04994267 0,07683246 ! adult walking behavior GO:0007628 36 18 0,000 0,04994267 0,07678411 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04994267 0,07673582 ! heart looping GO:0001947 34 18 0,000 0,04994267 0,07668759 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04994267 0,07663941 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04994267 0,0765913 ! centrosome cycle GO:0007098 26 18 0,000 0,04994267 0,07654325 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04994267 0,07649527 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04994267 0,07644734 ! glycine metabolic process GO:0006544 30 18 0,000 0,04994267 0,07639947 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04994267 0,07635166 ! response to retinoic acid GO:0032526 31 18 0,000 0,04994267 0,07630391 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04994267 0,07625622 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04994267 0,07620859 ! DNA integration GO:0015074 32 18 0,000 0,04994267 0,07616102 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04994267 0,0761135 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04994267 0,07606605 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04994267 0,07601866 ! neural crest cell migration GO:0001755 41 18 0,000 0,04994267 0,07597132 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04994267 0,07592405 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04994267 0,07587683 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04994267 0,07582968 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04994267 0,07578258 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04994267 0,07573554 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04994267 0,07568855 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04994267 0,07564163 ! detection of bacterium GO:0016045 22 18 0,000 0,04994267 0,07559476 ! nerve development GO:0021675 34 18 0,000 0,04994267 0,07554796 ! defense response to virus GO:0051607 43 18 0,000 0,04994267 0,07550121 ! microspike assembly GO:0030035 46 18 0,000 0,04994267 0,07545451 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04994267 0,07540788 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04994267 0,0753613 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05264367 0,07938796 ! positive regulation of translation GO:0045727 31 19 0,000 0,05264367 0,07933899 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05264367 0,07929007 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,05264367 0,07924122 ! neuron maturation GO:0042551 46 19 0,000 0,05264367 0,07919242 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05264367 0,07914369 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05264367 0,07909502 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05264367 0,0790464 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05264367 0,07899785 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05264367 0,07894935 ! memory GO:0007613 34 19 0,000 0,05264367 0,07890092 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05264367 0,07885254 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05264367 0,07880423 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,05264367 0,07875597 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05264367 0,07870777 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,05264367 0,07865963 ! cerebral cortex development GO:0021987 40 19 0,000 0,05264367 0,07861155 ! pigmentation during development GO:0048066 42 19 0,000 0,05264367 0,07856353 ! response to vitamin A GO:0033189 32 19 0,000 0,05264367 0,07851556 ! heme metabolic process GO:0042168 40 19 0,000 0,05264367 0,07846766 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05264367 0,07841981 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,05264367 0,07837203 ! response to fungus GO:0009620 26 19 0,000 0,05264367 0,0783243 ! peptide cross-linking GO:0018149 39 19 0,000 0,05264367 0,07827663 ! protein export from nucleus GO:0006611 40 19 0,000 0,05264367 0,07822901 ! heart process GO:0003015 32 19 0,000 0,05264367 0,07818146 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05264367 0,07813396 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05264367 0,07808652 ! visual learning GO:0008542 38 19 0,000 0,05264367 0,07803914 ! cellular pigmentation GO:0033059 37 19 0,000 0,05264367 0,07799181 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05264367 0,07794454 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05264367 0,07789733 ! vitamin transport GO:0051180 31 19 0,000 0,05264367 0,07785018 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05264367 0,07780308 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05264367 0,07775604 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05264367 0,07770906 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05264367 0,07766213 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05264367 0,07761527 ! cilium assembly GO:0042384 38 19 0,000 0,05264367 0,07756845 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05264367 0,0775217 ! protein secretion GO:0009306 45 20 0,000 0,05533707 0,08143884 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05533707 0,08138981 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,05533707 0,08134084 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05533707 0,08129192 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,05533707 0,08124307 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,05533707 0,08119428 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05533707 0,08114554 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,05533707 0,08109686 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,05533707 0,08104824 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05533707 0,08099968 ! response to vitamin GO:0033273 36 20 0,000 0,05533707 0,08095118 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,05533707 0,08090273 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05533707 0,08085435 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05533707 0,08080602 ! response to alkaloid GO:0043279 38 20 0,000 0,05533707 0,08075775 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05533707 0,08070953 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,05533707 0,08066138 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,05533707 0,08061328 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05533707 0,08056524 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05533707 0,08051725 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,05533707 0,08046933 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,05533707 0,08042146 ! actin filament bundle formation GO:0051017 47 20 0,000 0,05533707 0,08037364 ! body fluid secretion GO:0007589 33 20 0,000 0,05533707 0,08032589 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05533707 0,08027819 ! peptide secretion GO:0002790 38 20 0,000 0,05533707 0,08023054 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05533707 0,08018296 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,05533707 0,08013543 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05533707 0,08008796 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05533707 0,08004054 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05533707 0,07999318 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05533707 0,07994587 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,05533707 0,07989862 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05533707 0,07985143 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05533707 0,07980429 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05533707 0,07975721 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05533707 0,07971018 ! regulation of glucose import GO:0046324 30 20 0,000 0,05533707 0,07966321 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05533707 0,07961629 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05533707 0,07956943 ! negative regulation of translation GO:0017148 32 20 0,000 0,05533707 0,07952263 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05533707 0,07947588 ! regulation of cell killing GO:0031341 46 21 0,000 0,05802289 0,08328432 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05802289 0,08323542 ! hormone secretion GO:0046879 39 21 0,000 0,05802289 0,08318657 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05802289 0,08313778 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05802289 0,08308905 ! ovarian follicle development GO:0001541 39 21 0,000 0,05802289 0,08304037 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05802289 0,08299176 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05802289 0,08294319 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,05802289 0,08289469 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05802289 0,08284624 ! plasma membrane fusion GO:0045026 33 21 0,000 0,05802289 0,08279785 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05802289 0,08274951 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05802289 0,08270124 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,05802289 0,08265301 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05802289 0,08260485 ! diencephalon development GO:0021536 36 21 0,000 0,05802289 0,08255674 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05802289 0,08250868 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,05802289 0,08246069 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,05802289 0,08241274 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05802289 0,08236486 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,05802289 0,08231703 ! collagen catabolic process GO:0030574 29 21 0,000 0,05802289 0,08226925 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05802289 0,08222153 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05802289 0,08217387 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05802289 0,08212626 ! actin filament-based movement GO:0030048 47 21 0,000 0,05802289 0,0820787 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,05802289 0,0820312 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,06070115 0,08576802 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06070115 0,08571844 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,06070115 0,08566892 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06070115 0,08561946 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06070115 0,08557005 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06070115 0,0855207 ! microtubule-based transport GO:0010970 59 22 0,000 0,06070115 0,08547141 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,06070115 0,08542218 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06070115 0,085373 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,06070115 0,08532388 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,06070115 0,08527481 ! vacuolar transport GO:0007034 41 22 0,000 0,06070115 0,0852258 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06070115 0,08517685 ! fucose metabolic process GO:0006004 44 22 0,000 0,06070115 0,08512796 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06070115 0,08507912 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06070115 0,08503033 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,06070115 0,0849816 ! ureteric bud development GO:0001657 50 22 0,000 0,06070115 0,08493293 ! cell aging GO:0007569 48 22 0,000 0,06070115 0,08488431 ! stem cell differentiation GO:0048863 57 22 0,000 0,06070115 0,08483575 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06070115 0,08478725 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06070115 0,0847388 ! cytolysis GO:0019835 27 22 0,000 0,06070115 0,0846904 ! renal system process GO:0003014 42 22 0,000 0,06070115 0,08464207 ! vasodilation GO:0042311 40 22 0,000 0,06070115 0,08459378 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06070115 0,08454555 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,06070115 0,08449738 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,06070115 0,08444926 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06070115 0,08440119 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06070115 0,08435318 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,06070115 0,08430523 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06070115 0,08425733 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,06070115 0,08420948 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06070115 0,08416169 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06070115 0,08411395 ! sarcomere organization GO:0045214 32 22 0,000 0,06070115 0,08406627 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06070115 0,08401864 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06070115 0,08397106 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06070115 0,08392354 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06070115 0,08387607 ! gut development GO:0048565 44 22 0,000 0,06070115 0,08382866 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06070115 0,0837813 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06070115 0,08373399 ! protein stabilization GO:0050821 41 22 0,000 0,06070115 0,08368674 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06337186 0,08731949 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06337186 0,08727027 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06337186 0,0872211 ! gluconeogenesis GO:0006094 38 23 0,000 0,06337186 0,08717199 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06337186 0,08712294 ! viral genome replication GO:0019079 44 23 0,000 0,06337186 0,08707394 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06337186 0,08702499 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06337186 0,0869761 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,06337186 0,08692726 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06337186 0,08687848 ! regeneration GO:0031099 42 23 0,000 0,06337186 0,08682976 ! axis specification GO:0009798 43 23 0,000 0,06337186 0,08678109 ! visual behavior GO:0007632 46 23 0,000 0,06337186 0,08673247 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,06337186 0,08668391 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06337186 0,0866354 ! response to ethanol GO:0045471 47 23 0,000 0,06337186 0,08658695 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06337186 0,08653855 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,06337186 0,0864902 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06337186 0,08644191 ! peroxisome organization GO:0007031 43 23 0,000 0,06337186 0,08639367 ! lysosome organization GO:0007040 47 23 0,000 0,06337186 0,08634549 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,06337186 0,08629736 ! vesicle targeting GO:0006903 49 23 0,000 0,06337186 0,08624928 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,06337186 0,08620126 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06337186 0,08615329 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06337186 0,08610537 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06337186 0,08605751 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06337186 0,0860097 ! DNA modification GO:0006304 36 23 0,000 0,06337186 0,08596194 ! fatty acid transport GO:0015908 47 23 0,000 0,06337186 0,08591424 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06337186 0,08586659 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06337186 0,08581899 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06337186 0,08577144 ! hormone transport GO:0009914 41 23 0,000 0,06337186 0,08572395 ! cell-cell recognition GO:0009988 28 23 0,000 0,06337186 0,08567651 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06337186 0,08562913 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06337186 0,08558179 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06337186 0,08553451 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06603506 0,08907987 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06603506 0,08903071 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,06603506 0,0889816 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06603506 0,08893255 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06603506 0,08888355 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06603506 0,08883461 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06603506 0,08878572 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,06603506 0,08873688 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06603506 0,0886881 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06603506 0,08863937 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06603506 0,08859069 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06603506 0,08854207 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06603506 0,0884935 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,06603506 0,08844498 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,06603506 0,08839652 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06603506 0,08834811 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06603506 0,08829975 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06603506 0,08825145 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06603506 0,0882032 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06603506 0,088155 ! membrane depolarization GO:0051899 45 24 0,000 0,06603506 0,08810685 ! pallium development GO:0021543 56 24 0,000 0,06603506 0,08805876 ! oogenesis GO:0048477 44 24 0,000 0,06603506 0,08801072 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06603506 0,08796273 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,06603506 0,0879148 ! platelet activation GO:0030168 41 24 0,000 0,06603506 0,08786691 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06603506 0,08781908 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06603506 0,0877713 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06603506 0,08772357 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06603506 0,0876759 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06603506 0,08762827 ! regulation of amine transport GO:0051952 41 24 0,000 0,06603506 0,0875807 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,06603506 0,08753318 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,06869076 0,09100408 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,06869076 0,09095476 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06869076 0,09090548 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06869076 0,09085627 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06869076 0,0908071 ! phototransduction GO:0007602 37 25 0,000 0,06869076 0,09075799 ! keratinization GO:0031424 37 25 0,000 0,06869076 0,09070893 ! vasculogenesis GO:0001570 49 25 0,000 0,06869076 0,09065993 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,06869076 0,09061097 ! vacuole organization GO:0007033 49 25 0,000 0,06869076 0,09056207 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06869076 0,09051323 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,06869076 0,09046443 ! receptor metabolic process GO:0043112 53 25 0,000 0,06869076 0,09041569 ! chromosome condensation GO:0030261 48 25 0,000 0,06869076 0,090367 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,06869076 0,09031837 ! regulation of behavior GO:0050795 48 25 0,000 0,06869076 0,09026978 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06869076 0,09022125 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06869076 0,09017277 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06869076 0,09012434 ! immunoglobulin production GO:0002377 62 25 0,000 0,06869076 0,09007597 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06869076 0,09002764 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06869076 0,08997937 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06869076 0,08993115 ! liver development GO:0001889 55 25 0,000 0,06869076 0,08988298 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,07133898 0,09329825 ! initiation of viral infection GO:0019059 60 26 0,000 0,07133898 0,09324833 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,07133898 0,09319847 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,07133898 0,09314865 ! molting cycle process GO:0022404 52 26 0,000 0,07133898 0,0930989 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,07133898 0,09304919 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,07133898 0,09299954 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,07133898 0,09294994 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,07133898 0,09290039 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,07133898 0,0928509 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,07133898 0,09280146 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,07133898 0,09275207 ! digestive system process GO:0022600 49 26 0,000 0,07133898 0,09270273 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,07133898 0,09265345 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,07133898 0,09260422 ! osteoblast differentiation GO:0001649 63 26 0,000 0,07133898 0,09255504 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,07133898 0,09250591 ! neural crest cell development GO:0014032 59 26 0,000 0,07133898 0,09245683 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,07133898 0,09240781 ! negative regulation of cell development GO:0010721 83 26 0,000 0,07133898 0,09235884 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,07133898 0,09230992 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,07133898 0,09226106 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,07133898 0,09221224 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,07133898 0,09216348 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,07133898 0,09211476 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,07133898 0,0920661 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,07133898 0,09201749 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,07133898 0,09196894 ! blastocyst development GO:0001824 50 26 0,000 0,07133898 0,09192043 ! telomere organization GO:0032200 46 26 0,000 0,07133898 0,09187197 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,07133898 0,09182357 ! neural tube closure GO:0001843 58 26 0,000 0,07133898 0,09177522 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,07133898 0,09172691 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,07133898 0,09167866 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,07133898 0,09163046 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07397975 0,09497243 ! embryonic pattern specification GO:0009880 49 27 0,000 0,07397975 0,09492255 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,07397975 0,09487272 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,07397975 0,09482294 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07397975 0,09477322 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07397975 0,09472355 ! iron ion transport GO:0006826 65 27 0,000 0,07397975 0,09467393 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07397975 0,09462436 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07397975 0,09457484 ! tube lumen formation GO:0035148 59 27 0,000 0,07397975 0,09452538 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07397975 0,09447597 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,07397975 0,09442661 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,07397975 0,0943773 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07397975 0,09432804 ! response to toxin GO:0009636 49 27 0,000 0,07397975 0,09427884 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,07397975 0,09422968 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07397975 0,09418058 ! leukocyte proliferation GO:0070661 59 27 0,000 0,07397975 0,09413152 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,07661308 0,09743142 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07661308 0,09738073 ! protein amino acid acylation GO:0043543 59 28 0,000 0,07661308 0,09733009 ! vesicle docking GO:0048278 55 28 0,000 0,07661308 0,0972795 ! circadian rhythm GO:0007623 56 28 0,000 0,07661308 0,09722896 ! dendrite development GO:0016358 67 28 0,000 0,07661308 0,09717848 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,07661308 0,09712805 ! fat cell differentiation GO:0045444 57 28 0,000 0,07661308 0,09707767 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07661308 0,09702735 ! sperm motility GO:0030317 37 28 0,000 0,07661308 0,09697708 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07661308 0,09692685 ! base-excision repair GO:0006284 41 28 0,000 0,07661308 0,09687669 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07661308 0,09682657 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07661308 0,0967765 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07661308 0,09672649 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07661308 0,09667653 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07661308 0,09662662 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07661308 0,09657676 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07661308 0,09652695 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07661308 0,09647719 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,07661308 0,09642749 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,079239 0,09968119 ! translational initiation GO:0006413 66 29 0,000 0,079239 0,09962989 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,079239 0,09957864 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,079239 0,09952744 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,079239 0,0994763 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,079239 0,0994252 ! autophagy GO:0006914 47 29 0,000 0,079239 0,09937416 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,079239 0,09932318 ! primary neural tube formation GO:0014020 61 29 0,000 0,079239 0,09927224 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,079239 0,09922136 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,079239 0,09917053 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,079239 0,09911975 ! somitogenesis GO:0001756 52 29 0,000 0,079239 0,09906902 ! synaptogenesis GO:0007416 46 29 0,000 0,079239 0,09901835 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,079239 0,09896773 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,079239 0,09891716 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,079239 0,09886664 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,079239 0,09881617 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,08185752 0,10202955 ! phenol metabolic process GO:0018958 56 30 0,000 0,08185752 0,10197752 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,08185752 0,10192555 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,08185752 0,10187362 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,08185752 0,10182175 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,08185752 0,10176994 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,08185752 0,10171817 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,08185752 0,10166646 ! acute-phase response GO:0006953 50 30 0,000 0,08185752 0,1016148 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,08185752 0,10156319 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,08185752 0,10151164 ! myofibril assembly GO:0030239 50 30 0,000 0,08185752 0,10146013 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,08185752 0,10140868 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,08185752 0,10135729 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,08185752 0,10130594 ! cell fate determination GO:0001709 64 30 0,000 0,08185752 0,10125465 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,08185752 0,1012034 ! phospholipid transport GO:0015914 65 30 0,000 0,08185752 0,10115221 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,08185752 0,10110107 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,08185752 0,10104999 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,08185752 0,10099895 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,08185752 0,10094797 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,08185752 0,10089704 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08446867 0,10406302 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08446867 0,10401057 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08446867 0,10395817 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08446867 0,10390582 ! cell junction assembly GO:0034329 85 31 0,000 0,08446867 0,10385353 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08446867 0,10380129 ! ovulation cycle process GO:0022602 55 31 0,000 0,08446867 0,1037491 ! peptide transport GO:0015833 60 31 0,000 0,08446867 0,10369697 ! male gonad development GO:0008584 56 31 0,000 0,08446867 0,10364488 ! iron ion homeostasis GO:0055072 60 31 0,000 0,08446867 0,10359285 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,08446867 0,10354088 ! detection of light stimulus GO:0009583 44 31 0,000 0,08446867 0,10348895 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,08446867 0,10343708 ! natural killer cell activation GO:0030101 50 31 0,000 0,08446867 0,10338525 ! cofactor catabolic process GO:0051187 54 31 0,000 0,08446867 0,10333348 ! eye morphogenesis GO:0048592 65 31 0,000 0,08446867 0,10328176 ! response to heat GO:0009408 54 31 0,000 0,08446867 0,1032301 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08446867 0,10317848 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,08707247 0,10630587 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,08707247 0,10625277 ! collagen metabolic process GO:0032963 49 32 0,000 0,08707247 0,10619972 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,08707247 0,10614673 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,08707247 0,10609379 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,08707247 0,1060409 ! metanephros development GO:0001656 81 32 0,000 0,08707247 0,10598806 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,08707247 0,10593528 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,08707247 0,10588255 ! muscle cell development GO:0055001 52 32 0,000 0,08707247 0,10582987 ! mesoderm formation GO:0001707 73 32 0,000 0,08707247 0,10577725 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,08707247 0,10572467 ! ovulation cycle GO:0042698 57 32 0,000 0,08707247 0,10567215 ! BMP signaling pathway GO:0030509 71 32 0,000 0,08707247 0,10561968 ! hindbrain development GO:0030902 65 32 0,000 0,08707247 0,10556727 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,08707247 0,1055149 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,08707247 0,10546259 ! gene silencing GO:0016458 71 32 0,000 0,08707247 0,10541033 ! regulation of pH GO:0006885 56 33 0,000 0,08966894 0,10849986 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,08966894 0,10844614 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,08966894 0,10839248 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,08966894 0,10833888 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,08966894 0,10828532 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,08966894 0,10823182 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,08966894 0,10817837 ! response to ionizing radiation GO:0010212 74 33 0,000 0,08966894 0,10812498 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,08966894 0,10807164 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,08966894 0,10801835 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,08966894 0,10796511 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,08966894 0,10791193 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,08966894 0,10785879 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,09225809 0,11091856 ! glial cell differentiation GO:0010001 67 34 0,000 0,09225809 0,110864 ! post-embryonic development GO:0009791 76 34 0,000 0,09225809 0,11080949 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,09225809 0,11075504 ! cholesterol transport GO:0030301 62 34 0,000 0,09225809 0,11070064 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,09225809 0,1106463 ! spliceosome assembly GO:0000245 75 34 0,000 0,09225809 0,11059201 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,09225809 0,11053777 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,09225809 0,11048358 ! formation of primary germ layer GO:0001704 76 34 0,000 0,09225809 0,11042945 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,09225809 0,11037537 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,09225809 0,11032135 ! adult locomotory behavior GO:0008344 62 34 0,000 0,09225809 0,11026737 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,09483995 0,1132978 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,09483995 0,11324242 ! negative regulation of secretion GO:0051048 68 35 0,000 0,09483995 0,1131871 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,09483995 0,11313184 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,09483995 0,11307662 ! membrane docking GO:0022406 69 35 0,000 0,09483995 0,11302146 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,09483995 0,11296636 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,09483995 0,11291131 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,09483995 0,11285631 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,09483995 0,11280136 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,09483995 0,11274647 ! ceramide metabolic process GO:0006672 72 35 0,000 0,09483995 0,11269163 ! telencephalon development GO:0021537 81 35 0,000 0,09483995 0,11263685 ! sterol transport GO:0015918 63 35 0,000 0,09483995 0,11258212 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,09483995 0,11252744 ! placenta development GO:0001890 53 35 0,000 0,09483995 0,11247282 ! vesicle localization GO:0051648 70 35 0,000 0,09483995 0,11241824 ! regulation of muscle development GO:0048634 82 36 0,000 0,09741454 0,11541403 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,09741454 0,11535808 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,09741454 0,11530219 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,09741454 0,11524636 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,09741454 0,11519057 ! protein targeting to membrane GO:0006612 75 36 0,000 0,09741454 0,11513485 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,09741454 0,11507917 ! aerobic respiration GO:0009060 56 36 0,000 0,09741454 0,11502355 ! cytokine production GO:0001816 68 36 0,000 0,09741454 0,11496798 ! embryonic organ development GO:0048568 67 36 0,000 0,09741454 0,11491247 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,09741454 0,11485701 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,09741454 0,11480161 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,09998188 0,11777037 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,09998188 0,11771361 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,09998188 0,11765691 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,09998188 0,11760026 ! actomyosin structure organization GO:0031032 68 37 0,000 0,09998188 0,11754367 ! cell junction organization GO:0034330 96 37 0,000 0,09998188 0,11748713 ! tissue remodeling GO:0048771 78 37 0,000 0,09998188 0,11743064 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,09998188 0,11737421 ! female gonad development GO:0008585 71 37 0,000 0,09998188 0,11731784 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,09998188 0,11726152 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,09998188 0,11720525 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,10254199 0,12014872 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,10254199 0,12009113 ! organic anion transport GO:0015711 82 38 0,000 0,10254199 0,12003358 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,10254199 0,1199761 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,10254199 0,11991866 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,10254199 0,11986129 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,10254199 0,11980396 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,10254199 0,1197467 ! regulation of protein stability GO:0031647 77 38 0,000 0,10254199 0,11968948 ! spermatid development GO:0007286 69 38 0,000 0,10254199 0,11963233 ! glycogen metabolic process GO:0005977 63 38 0,000 0,10254199 0,11957522 ! pigment metabolic process GO:0042440 87 38 0,000 0,10254199 0,11951817 ! neural tube formation GO:0001841 79 38 0,000 0,10254199 0,11946118 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,10509489 0,12237694 ! negative regulation of binding GO:0051100 71 39 0,000 0,10509489 0,12231864 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,10509489 0,12226039 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,10509489 0,1222022 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,10509489 0,12214406 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,10509489 0,12208598 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,10509489 0,12202796 ! glucan metabolic process GO:0044042 64 39 0,000 0,10509489 0,12196999 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,1076406 0,12486514 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,1076406 0,12480588 ! learning GO:0007612 82 40 0,000 0,1076406 0,12474668 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,1076406 0,12468753 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,1076406 0,12462843 ! lipid homeostasis GO:0055088 75 40 0,000 0,1076406 0,12456939 ! mismatch repair GO:0006298 58 40 0,000 0,1076406 0,12451041 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,1076406 0,12445149 ! RNA export from nucleus GO:0006405 61 41 0,000 0,11017914 0,12732623 ! mRNA catabolic process GO:0006402 79 41 0,000 0,11017914 0,12726603 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,11017914 0,12720588 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,11017914 0,12714579 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,11017914 0,12708576 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,11017914 0,12702579 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,11017914 0,12696587 ! gliogenesis GO:0042063 91 41 0,000 0,11017914 0,12690601 ! feeding behavior GO:0007631 69 41 0,000 0,11017914 0,1268462 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,11017914 0,12678645 ! mesenchymal cell development GO:0014031 94 41 0,000 0,11017914 0,12672676 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,11017914 0,12666713 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,11017914 0,12660755 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,11017914 0,12654802 ! spermatid differentiation GO:0048515 73 41 0,000 0,11017914 0,12648855 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,11017914 0,12642914 ! RNA modification GO:0009451 64 41 0,000 0,11017914 0,12636979 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,11271053 0,1292125 ! ear morphogenesis GO:0042471 64 42 0,000 0,11271053 0,12915189 ! organic ether metabolic process GO:0018904 59 42 0,000 0,11271053 0,12909134 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,11271053 0,12903085 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,11271053 0,12897041 ! T cell differentiation GO:0030217 93 42 0,000 0,11271053 0,12891003 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,11271053 0,12884971 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,11271053 0,12878944 ! regulation of protein secretion GO:0050708 77 42 0,000 0,11271053 0,12872923 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,11271053 0,12866908 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,11271053 0,12860898 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,11523479 0,13142791 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,11523479 0,13136658 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,11523479 0,13130531 ! regulation of tube size GO:0035150 76 43 0,000 0,11523479 0,1312441 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,11523479 0,13118294 ! glucose transport GO:0015758 66 43 0,000 0,11523479 0,13112184 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,11523479 0,1310608 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,11523479 0,13099981 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,11523479 0,13093888 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,11523479 0,13087801 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,11523479 0,13081719 ! segmentation GO:0035282 78 43 0,000 0,11523479 0,13075643 ! ion transmembrane transport GO:0034220 79 43 0,000 0,11523479 0,13069572 ! neuron migration GO:0001764 85 43 0,000 0,11523479 0,13063508 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,11523479 0,13057449 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,11775194 0,13336485 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,11775194 0,13330305 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,11775194 0,13324131 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,11775194 0,13317962 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,11775194 0,13311799 ! hexose transport GO:0008645 68 44 0,000 0,11775194 0,13305642 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,11775194 0,13299491 ! striated muscle contraction GO:0006941 85 44 0,000 0,11775194 0,13293345 ! phagocytosis GO:0006909 105 44 0,000 0,11775194 0,13287205 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,11775194 0,1328107 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,120262 0,13557917 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,120262 0,13551663 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,120262 0,13545415 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,120262 0,13539173 ! biopolymer methylation GO:0043414 91 45 0,000 0,120262 0,13532937 ! B cell differentiation GO:0030183 124 45 0,000 0,120262 0,13526706 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,120262 0,13520481 ! female gamete generation GO:0007292 71 45 0,000 0,120262 0,13514262 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,120262 0,13508049 ! developmental growth GO:0048589 88 45 0,000 0,120262 0,13501841 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,12276498 0,13776521 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,12276498 0,13770195 ! glycolysis GO:0006096 71 46 0,000 0,12276498 0,13763876 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,12276498 0,13757562 ! leukocyte migration GO:0050900 75 46 0,000 0,12276498 0,13751254 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,12276498 0,13744952 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,12276498 0,13738656 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,12276498 0,13732365 ! pigmentation GO:0043473 103 46 0,000 0,12276498 0,1372608 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,12276498 0,13719801 ! neural tube development GO:0021915 91 47 0,000 0,12526092 0,13992338 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,12526092 0,13985943 ! positive regulation of defense response GO:0031349 88 48 0,000 0,12774982 0,14257324 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,12774982 0,14250814 ! mitochondrial transport GO:0006839 94 48 0,000 0,12774982 0,14244309 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,12774982 0,14237811 ! cellular component disassembly GO:0022411 89 48 0,000 0,12774982 0,14231319 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,12774982 0,14224832 ! endosome transport GO:0016197 127 48 0,000 0,12774982 0,14218352 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,12774982 0,14211877 ! male sex differentiation GO:0046661 93 48 0,000 0,12774982 0,14205408 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,12774982 0,14198945 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,12774982 0,14192488 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,12774982 0,14186037 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,12774982 0,14179592 ! methylation GO:0032259 97 48 0,000 0,12774982 0,14173153 ! response to calcium ion GO:0051592 94 49 0,000 0,13023172 0,14441947 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,13023172 0,14435394 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,13023172 0,14428847 ! JNK cascade GO:0007254 106 49 0,000 0,13023172 0,14422307 ! protein homooligomerization GO:0051260 84 49 0,000 0,13023172 0,14415772 ! regulation of ion transport GO:0043269 86 50 0,000 0,13270662 0,14683074 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,13270662 0,14676427 ! endocrine system development GO:0035270 109 50 0,000 0,13270662 0,14669786 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,13270662 0,14663151 ! activation of caspase activity GO:0006919 95 50 0,000 0,13270662 0,14656522 ! regulation of ossification GO:0030278 123 50 0,000 0,13270662 0,14649899 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,13270662 0,14643282 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,13270662 0,14636671 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,13270662 0,14630066 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,13270662 0,14623467 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,13270662 0,14616874 ! viral infectious cycle GO:0019058 104 51 0,000 0,13517454 0,14881992 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,13517454 0,14875289 ! peptide metabolic process GO:0006518 80 51 0,000 0,13517454 0,14868591 ! response to temperature stimulus GO:0009266 84 51 0,000 0,13517454 0,148619 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,13517454 0,14855214 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,13763552 0,15118866 ! Notch signaling pathway GO:0007219 111 52 0,000 0,13763552 0,15112071 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,13763552 0,15105282 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,13763552 0,15098499 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,13763552 0,15091722 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,13763552 0,15084952 ! excretion GO:0007588 87 52 0,000 0,13763552 0,15078187 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,13763552 0,15071429 ! histone modification GO:0016570 104 52 0,000 0,13763552 0,15064676 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,13763552 0,1505793 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,13763552 0,1505119 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,13763552 0,15044455 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,14008956 0,1530585 ! inner ear development GO:0048839 89 53 0,000 0,14008956 0,15299007 ! chromatin remodeling GO:0006338 122 53 0,000 0,14008956 0,15292171 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,14008956 0,15285341 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,14008956 0,15278518 ! vesicle organization GO:0016050 127 53 0,000 0,14008956 0,152717 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,14008956 0,15264888 ! cartilage development GO:0051216 99 53 0,000 0,14008956 0,15258083 ! regulation of translational initiation GO:0006446 87 54 0,000 0,14253669 0,15517697 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,14253669 0,15510785 ! neuromuscular process GO:0050905 107 54 0,000 0,14253669 0,15503879 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,14253669 0,15496979 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,14253669 0,15490086 ! membrane fusion GO:0006944 122 54 0,000 0,14253669 0,15483198 ! covalent chromatin modification GO:0016569 115 54 0,000 0,14253669 0,15476317 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,14253669 0,15469441 ! regulation of cell shape GO:0008360 142 54 0,000 0,14253669 0,15462572 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,14253669 0,15455709 ! RNA catabolic process GO:0006401 103 55 0,000 0,14497692 0,15713337 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,14497692 0,15706368 ! cell recognition GO:0008037 98 55 0,000 0,14497692 0,15699406 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,14497692 0,15692451 ! cell maturation GO:0048469 107 55 0,000 0,14497692 0,15685501 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,14497692 0,15678557 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,14497692 0,1567162 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,14741027 0,15927611 ! glucose catabolic process GO:0006007 88 56 0,000 0,14741027 0,1592057 ! RNA elongation GO:0006354 90 56 0,000 0,14741027 0,15913535 ! chloride transport GO:0006821 102 57 0,000 0,14983677 0,16168341 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,14983677 0,16161202 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,14983677 0,1615407 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,14983677 0,16146944 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,14983677 0,16139825 ! regulation of actin filament length GO:0030832 118 58 0,000 0,15225643 0,16393233 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,15225643 0,16386011 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,15225643 0,16378796 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,15225643 0,16371587 ! aging GO:0007568 112 58 0,000 0,15225643 0,16364385 ! gastrulation GO:0007369 122 58 0,000 0,15225643 0,16357188 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,15225643 0,16349998 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,15225643 0,16342815 ! nuclear export GO:0051168 110 59 0,000 0,15466927 0,16594512 ! DNA catabolic process GO:0006308 94 60 0,000 0,15707531 0,16845259 ! regulation of endocytosis GO:0030100 104 60 0,000 0,15707531 0,16837867 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,15707531 0,16830482 ! adult behavior GO:0030534 104 60 0,000 0,15707531 0,16823104 ! kidney development GO:0001822 133 60 0,000 0,15707531 0,16815732 ! positive regulation of secretion GO:0051047 110 61 0,000 0,15947458 0,17065107 ! regulation of cellular component size GO:0032535 125 61 0,000 0,15947458 0,17057635 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,15947458 0,1705017 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,15947458 0,17042712 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,15947458 0,1703526 ! regulation of heart contraction GO:0008016 123 61 0,000 0,15947458 0,17027814 ! camera-type eye development GO:0043010 126 61 0,000 0,15947458 0,17020375 ! proton transport GO:0015992 117 61 0,000 0,15947458 0,17012943 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,15947458 0,17005517 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,16186708 0,17253109 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,16186708 0,17245585 ! tRNA processing GO:0008033 102 62 0,000 0,16186708 0,17238067 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,16186708 0,17230556 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,16425283 0,17476902 ! mesoderm development GO:0007498 128 63 0,000 0,16425283 0,17469293 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,16425283 0,17461691 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,16425283 0,17454096 ! hydrogen transport GO:0006818 121 64 0,000 0,16663187 0,17699202 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,16663187 0,1769151 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,16663187 0,17683825 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,16900419 0,179278 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,16900419 0,17920019 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,16900419 0,17912245 GO:0048609|reproductive process in a multicellular organism, ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,16900419 0,17904477 ! ear development GO:0043583 114 66 0,000 0,17136983 0,18147226 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,17136983 0,18139363 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,17136983 0,18131507 ! gonad development GO:0008406 115 66 0,000 0,17136983 0,18123658 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,17136983 0,18115816 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,17372881 0,18357244 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,17372881 0,18349307 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,17372881 0,18341377 ! secondary metabolic process GO:0019748 125 67 0,000 0,17372881 0,18333455 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,17372881 0,18325539 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,17608113 0,18565654 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,17608113 0,18557645 ! hexose catabolic process GO:0019320 113 68 0,000 0,17608113 0,18549642 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,17608113 0,18541647 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,17608113 0,18533658 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,17608113 0,18525676 ! adaptive immune response GO:0002250 126 68 0,000 0,17608113 0,18517701 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,17608113 0,18509733 ! cell projection assembly GO:0030031 138 68 0,000 0,17608113 0,18501772 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,17842682 0,18740186 ! urogenital system development GO:0001655 149 69 0,000 0,17842682 0,18732133 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,17842682 0,18724086 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,17842682 0,18716047 ! developmental maturation GO:0021700 128 69 0,000 0,17842682 0,18708014 ! single fertilization GO:0007338 83 69 0,000 0,17842682 0,18699988 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1807659 0,18937011 ! germ cell development GO:0007281 133 70 0,000 0,1807659 0,18928894 ! activation of immune response GO:0002253 120 70 0,000 0,1807659 0,18920784 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,1807659 0,18912681 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,18309839 0,19148518 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,18309839 0,19140324 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,18309839 0,19132137 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,18309839 0,19123958 ! appendage morphogenesis GO:0035107 150 72 0,000 0,1854243 0,19358614 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,1854243 0,19350345 ! actin filament organization GO:0007015 167 72 0,000 0,1854243 0,19342083 ! B cell activation GO:0042113 179 72 0,000 0,1854243 0,19333827 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,1854243 0,19325579 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,1854243 0,19317338 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,1854243 0,19309104 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,1854243 0,19300877 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,1854243 0,19292656 ! appendage development GO:0048736 151 73 0,000 0,18774366 0,1952566 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,18774366 0,19517351 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,18774366 0,1950905 ! regulation of immune effector process GO:0002697 156 73 0,000 0,18774366 0,19500755 ! acute inflammatory response GO:0002526 118 74 0,000 0,19005647 0,19732595 ! amino acid transport GO:0006865 148 74 0,000 0,19005647 0,19724213 ! regulation of caspase activity GO:0043281 136 74 0,000 0,19005647 0,19715837 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,19005647 0,19707469 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,19236277 0,19938152 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,19236277 0,19929697 ! reproductive structure development GO:0048608 131 75 0,000 0,19236277 0,19921248 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,19236277 0,19912807 ! eye development GO:0001654 155 75 0,000 0,19236277 0,19904373 ! rhythmic process GO:0048511 142 75 0,000 0,19236277 0,19895946 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,19466256 0,20125292 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,19466256 0,20116778 ! learning or memory GO:0007611 161 76 0,000 0,19466256 0,20108272 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,19466256 0,20099773 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,19466256 0,20091282 ! amine catabolic process GO:0009310 136 77 0,000 0,19695587 0,20319392 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,19695587 0,20310814 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,19695587 0,20302244 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,19695587 0,20293682 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,19695587 0,20285126 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,19695587 0,20276578 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,19924271 0,20503368 ! antigen processing and presentation GO:0019882 117 78 0,000 0,19924271 0,20494735 ! fertilization GO:0009566 99 78 0,000 0,19924271 0,20486109 ! blood coagulation GO:0007596 151 79 0,000 0,20152311 0,20711862 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,20152311 0,20703152 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,20152311 0,2069445 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,20152311 0,20685754 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,20379707 0,20910384 ! muscle cell differentiation GO:0042692 178 81 0,000 0,20606463 0,21134168 ! response to hypoxia GO:0001666 178 81 0,000 0,20606463 0,21125299 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,20606463 0,21116438 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,20832579 0,21339199 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,20832579 0,21330255 ! protein import into nucleus GO:0006606 174 82 0,000 0,20832579 0,21321319 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,21058057 0,21543062 ! response to drug GO:0042493 149 83 0,000 0,21058057 0,21534045 ! response to oxygen levels GO:0070482 183 83 0,000 0,21058057 0,21525035 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,21058057 0,21516032 ! nuclear import GO:0051170 177 83 0,000 0,21058057 0,21507037 ! inorganic anion transport GO:0015698 156 83 0,000 0,21058057 0,2149805 ! response to metal ion GO:0010038 158 84 0,000 0,21282899 0,21718514 ! T cell activation GO:0042110 189 84 0,000 0,21282899 0,21709446 ! response to nutrient GO:0007584 135 84 0,000 0,21282899 0,21700385 ! digestion GO:0007586 130 84 0,000 0,21282899 0,21691332 ! regulation of ligase activity GO:0051340 147 84 0,000 0,21282899 0,21682286 ! hemostasis GO:0007599 165 85 0,000 0,21507107 0,21901569 ! negative regulation of transport GO:0051051 164 85 0,000 0,21507107 0,21892443 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,21507107 0,21883325 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,21507107 0,21874215 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,21730684 0,22092409 ! regulation of lyase activity GO:0051339 169 86 0,000 0,21730684 0,2208322 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,21953629 0,22300505 ! mitochondrion organization GO:0007005 159 87 0,000 0,21953629 0,22291237 ! alcohol catabolic process GO:0046164 142 87 0,000 0,21953629 0,22281976 ! regulation of protein transport GO:0051223 165 87 0,000 0,21953629 0,22272722 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,22175946 0,22488931 ! amine biosynthetic process GO:0009309 146 88 0,000 0,22175946 0,224796 ! sensory perception of smell GO:0007608 117 88 0,000 0,22175946 0,22470276 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,22175946 0,2246096 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,22397635 0,22676097 ! tube morphogenesis GO:0035239 194 89 0,000 0,22397635 0,22666704 ! cellular defense response GO:0006968 123 89 0,000 0,22397635 0,22657318 ! protein localization in nucleus GO:0034504 192 89 0,000 0,22397635 0,2264794 ! response to inorganic substance GO:0010035 173 90 0,000 0,226187 0,22862012 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,226187 0,22852557 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,226187 0,2284311 ! response to unfolded protein GO:0006986 139 90 0,000 0,226187 0,22833671 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,22839141 0,23046683 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,22839141 0,23037168 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,23278159 0,23470302 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,23278159 0,2346062 ! vitamin metabolic process GO:0006766 153 93 0,000 0,23278159 0,23450945 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,2349674 0,23661391 ! sterol metabolic process GO:0016125 166 94 0,000 0,2349674 0,23651642 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,2349674 0,23641901 ! regulation of defense response GO:0031347 171 95 0,000 0,23714704 0,23851388 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,23714704 0,23841573 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,23714704 0,23831765 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,23714704 0,23821966 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,23714704 0,23812175 ! sex differentiation GO:0007548 171 96 0,000 0,23932053 0,24020545 ! response to protein stimulus GO:0051789 158 96 0,000 0,23932053 0,2401068 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,24148789 0,24218182 ! transcription initiation GO:0006352 171 97 0,000 0,24148789 0,24208245 ! regulation of protein localization GO:0032880 188 97 0,000 0,24148789 0,24198315 ! leukocyte differentiation GO:0002521 232 98 0,000 0,24364914 0,24404873 ! forebrain development GO:0030900 210 98 0,000 0,24364914 0,24394871 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,24364914 0,24384877 ! mRNA transport GO:0051028 185 100 0,000 0,24795336 0,24805489 ! positive regulation of immune response GO:0050778 175 100 0,000 0,24795336 0,24795336