pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6906-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cell migration GO:0030335 36 36 7,000 1,135E-09 2,092E-06 ! positive regulation of cell motion GO:0051272 39 39 7,000 2,256E-09 2,079E-06 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 4,000 8,522E-09 5,235E-06 ! regulation of cell migration GO:0030334 71 71 8,000 1,828E-08 8,423E-06 ! regulation of locomotion GO:0040012 79 79 8,000 4,757E-08 1,753E-05 ! regulation of cell motion GO:0051270 79 79 8,000 4,757E-08 1,461E-05 ! response to hypoxia GO:0001666 53 53 6,000 5,879E-07 1,548E-04 ! response to oxygen levels GO:0070482 55 54 6,000 6,704E-07 1,545E-04 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 3,000 9,39E-07 1,923E-04 ! peptidyl-amino acid modification GO:0018193 61 59 6,000 1,244E-06 2,292E-04 ! mitochondrial membrane organization GO:0007006 13 13 3,000 5,176E-06 8,673E-04 ! prostate gland development GO:0030850 5 5 2,000 8,319E-06 1,278E-03 ! actin cytoskeleton reorganization GO:0031532 5 5 2,000 8,319E-06 1,179E-03 ! T cell lineage commitment GO:0002360 5 5 2,000 8,319E-06 1,095E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 2,000 8,319E-06 1,022E-03 ! regulation of DNA replication GO:0006275 32 31 4,000 9,763E-06 1,125E-03 ! cellular response to nutrient levels GO:0031669 16 16 3,000 1,289E-05 1,398E-03 ! regulation of angiogenesis GO:0045765 35 34 4,000 1,564E-05 1,601E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 6,000 1,598E-05 1,55E-03 ! ER overload response GO:0006983 6 6 2,000 1,652E-05 1,523E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 1,652E-05 1,45E-03 ! protein sumoylation GO:0016925 6 6 2,000 1,652E-05 1,384E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 2,000 1,652E-05 1,324E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of fibroblast proliferation GO:0048145 17 17 3,000 1,674E-05 1,285E-03 ! response to toxin GO:0009636 18 17 3,000 1,674E-05 1,234E-03 ! protein polymerization GO:0051258 65 60 5,000 2,064E-05 1,463E-03 ! cellular response to extracellular stimulus GO:0031668 18 18 3,000 2,137E-05 1,459E-03 ! lung development GO:0030324 38 37 4,000 2,396E-05 1,577E-03 ! negative regulation of growth GO:0045926 37 37 4,000 2,396E-05 1,523E-03 ! regulation of endothelial cell proliferation GO:0001936 19 19 3,000 2,687E-05 1,651E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 3,000 2,687E-05 1,598E-03 ! regulation of protein stability GO:0031647 19 19 3,000 2,687E-05 1,548E-03 ! response to gamma radiation GO:0010332 8 7 2,000 2,872E-05 1,604E-03 ! regulation of mRNA stability GO:0043488 7 7 2,000 2,872E-05 1,557E-03 ! respiratory tube development GO:0030323 40 39 4,000 3,118E-05 1,642E-03 ! respiratory system development GO:0060541 40 39 4,000 3,118E-05 1,596E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 3,000 3,335E-05 1,661E-03 ! posttranscriptional regulation of gene expression GO:0010608 98 98 6,000 3,758E-05 1,823E-03 ! regulation of cell size GO:0008361 68 68 5,000 4,25E-05 2,008E-03 ! negative regulation of bone remodeling GO:0046851 8 8 2,000 4,563E-05 2,103E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 2,000 4,563E-05 2,051E-03 ! negative regulation of blood coagulation GO:0030195 9 8 2,000 4,563E-05 2,002E-03 ! peptidyl-serine modification GO:0018209 8 8 2,000 4,563E-05 1,956E-03 ! regulation of RNA stability GO:0043487 8 8 2,000 4,563E-05 1,911E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 2,000 4,563E-05 1,869E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 4,563E-05 1,828E-03 ! response to nutrient levels GO:0031667 69 69 5,000 4,62E-05 1,812E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 5,000 4,62E-05 1,774E-03 ! response to extracellular stimulus GO:0009991 72 72 5,000 5,887E-05 2,214E-03 ! mitotic cell cycle checkpoint GO:0007093 24 23 3,000 5,964E-05 2,198E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 2,000 6,798E-05 2,457E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 2,000 6,798E-05 2,409E-03 ! defense response to virus GO:0051607 9 9 2,000 6,798E-05 2,364E-03 ! mitochondrial transport GO:0006839 24 24 3,000 7,106E-05 2,425E-03 ! glucose homeostasis GO:0042593 24 24 3,000 7,106E-05 2,381E-03 GO:0033500|carbohydrate homeostasis, ! gland development GO:0048732 51 49 4,000 9,591E-05 3,156E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 9,591E-05 3,101E-03 ! regulation of glucose metabolic process GO:0010906 10 10 2,000 9,645E-05 3,065E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 9,645E-05 3,013E-03 ! negative regulation of homeostatic process GO:0032845 10 10 2,000 9,645E-05 2,963E-03 ! negative regulation of coagulation GO:0050819 11 10 2,000 9,645E-05 2,914E-03 ! regulation of DNA metabolic process GO:0051052 51 50 4,000 1,058E-04 3,144E-03 ! tube development GO:0035295 83 81 5,000 1,143E-04 3,344E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 1,164E-04 3,352E-03 GO:0051325|interphase, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 1,317E-04 3,735E-03 GO:0032388|positive regulation of intracellular transport, ! cellular response to starvation GO:0009267 11 11 2,000 1,317E-04 3,678E-03 ! G1/S transition checkpoint GO:0031575 12 11 2,000 1,317E-04 3,623E-03 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 2,000 1,317E-04 3,57E-03 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 2,000 1,317E-04 3,518E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 1,33E-04 3,502E-03 ! negative regulation of multicellular organismal process GO:0051241 55 54 4,000 1,533E-04 3,979E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 1,595E-04 4,083E-03 ! positive regulation of multicellular organism growth GO:0040018 12 12 2,000 1,744E-04 4,403E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 1,811E-04 4,512E-03 GO:0033674|positive regulation of kinase activity, ! reproductive developmental process GO:0003006 56 56 4,000 1,824E-04 4,483E-03 ! positive regulation of DNA replication GO:0045740 14 13 2,000 2,252E-04 5,461E-03 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 2,252E-04 5,39E-03 ! cell aging GO:0007569 13 13 2,000 2,252E-04 5,321E-03 ! regulation of endothelial cell migration GO:0010594 13 13 2,000 2,252E-04 5,253E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 2,252E-04 5,188E-03 ! negative regulation of phosphorylation GO:0042326 13 13 2,000 2,252E-04 5,124E-03 ! positive regulation of locomotion GO:0040017 13 13 2,000 2,252E-04 5,061E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of cell growth GO:0030308 32 32 3,000 2,27E-04 5,04E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 3,000 2,27E-04 4,98E-03 ! negative regulation of cell size GO:0045792 33 33 3,000 2,564E-04 5,56E-03 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 2,000 2,846E-04 6,1E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of behavior GO:0050795 14 14 2,000 2,846E-04 6,03E-03 ! regulation of blood coagulation GO:0030193 15 14 2,000 2,846E-04 5,961E-03 ! positive regulation of fibroblast proliferation GO:0048146 15 15 2,000 3,534E-04 7,317E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 3,534E-04 7,236E-03 ! response to starvation GO:0042594 15 15 2,000 3,534E-04 7,156E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 3,534E-04 7,079E-03 ! negative regulation of cell activation GO:0050866 15 15 2,000 3,534E-04 7,003E-03 ! regulation of MAP kinase activity GO:0043405 67 66 4,000 3,965E-04 7,773E-03 ! response to drug GO:0042493 37 37 3,000 4,022E-04 7,802E-03 ! regulation of coagulation GO:0050818 17 16 2,000 4,319E-04 8,292E-03 ! cell-matrix adhesion GO:0007160 39 38 3,000 4,463E-04 8,479E-03 ! urogenital system development GO:0001655 38 38 3,000 4,463E-04 8,392E-03 ! regulation of homeostatic process GO:0032844 38 38 3,000 4,463E-04 8,308E-03 ! tissue remodeling GO:0048771 17 17 2,000 5,209E-04 9,6E-03 ! development of primary male sexual characteristics GO:0046546 17 17 2,000 5,209E-04 9,505E-03 ! pigmentation GO:0043473 17 17 2,000 5,209E-04 9,412E-03 ! cell cycle checkpoint GO:0000075 42 41 3,000 5,992E-04 0,01072103 ! regulation of cellular catabolic process GO:0031329 18 18 2,000 6,208E-04 0,01100121 ! B cell differentiation GO:0030183 18 18 2,000 6,208E-04 0,01089644 ! cell-substrate adhesion GO:0031589 43 42 3,000 6,575E-04 0,01143173 ! response to oxidative stress GO:0006979 76 75 4,000 7,165E-04 0,01234179 ! reproductive structure development GO:0048608 43 43 3,000 7,197E-04 0,01228222 ! mitochondrion organization GO:0007005 44 43 3,000 7,197E-04 0,01216954 ! DNA damage checkpoint GO:0000077 19 19 2,000 7,322E-04 0,01226694 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 7,322E-04 0,01215643 ! cellular response to oxidative stress GO:0034599 19 19 2,000 7,322E-04 0,01204789 ! positive regulation of gene-specific transcription GO:0043193 20 20 2,000 8,555E-04 0,01395257 ! microtubule-based movement GO:0007018 82 78 4,000 8,573E-04 0,0138594 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 8,897E-04 0,01425834 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 8,897E-04 0,01413543 ! metencephalon development GO:0022037 5 5 1,000 8,897E-04 0,01401461 ! mRNA stabilization GO:0048255 5 5 1,000 8,897E-04 0,01389584 GO:0043489|RNA stabilization, ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 8,897E-04 0,01377907 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 8,897E-04 0,01366425 ! heart looping GO:0001947 5 5 1,000 8,897E-04 0,01355132 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 8,897E-04 0,01344024 ! receptor clustering GO:0043113 5 5 1,000 8,897E-04 0,01333097 ! fear response GO:0042596 5 5 1,000 8,897E-04 0,01322346 ! cellular glucose homeostasis GO:0001678 5 5 1,000 8,897E-04 0,01311768 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 8,897E-04 0,01301357 ! response to UV-B GO:0010224 5 5 1,000 8,897E-04 0,0129111 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 8,897E-04 0,01281023 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 8,897E-04 0,01271093 ! cellular pigmentation GO:0033059 5 5 1,000 8,897E-04 0,01261315 ! DNA methylation GO:0006306 5 5 1,000 8,897E-04 0,01251687 GO:0006305|DNA alkylation, ! regulation of hormone metabolic process GO:0032350 5 5 1,000 8,897E-04 0,01242204 ! cellular response to nutrient GO:0031670 5 5 1,000 8,897E-04 0,01232864 ! peptidyl-lysine modification GO:0018205 5 5 1,000 8,897E-04 0,01223664 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 8,897E-04 0,012146 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 8,897E-04 0,01205669 ! oocyte differentiation GO:0009994 5 5 1,000 8,897E-04 0,01196868 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 8,897E-04 0,01188195 ! spleen development GO:0048536 5 5 1,000 8,897E-04 0,01179647 ! male genitalia development GO:0030539 5 5 1,000 8,897E-04 0,01171221 ! response to nicotine GO:0035094 5 5 1,000 8,897E-04 0,01162915 ! regulation of membrane potential GO:0042391 46 46 3,000 9,314E-04 0,01208881 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 9,912E-04 0,01277519 ! DNA integrity checkpoint GO:0031570 21 21 2,000 9,912E-04 0,01268647 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 9,912E-04 0,01259898 ! sex differentiation GO:0007548 47 47 3,000 1,011E-03 0,01275939 ! regulation of catabolic process GO:0009894 48 47 3,000 1,011E-03 0,01267259 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 1,14E-03 0,01419501 ! spindle organization GO:0007051 22 22 2,000 1,14E-03 0,01409974 ! male sex differentiation GO:0046661 22 22 2,000 1,14E-03 0,01400574 ! cell cycle arrest GO:0007050 49 49 3,000 1,184E-03 0,01444586 ! response to nutrient GO:0007584 49 49 3,000 1,184E-03 0,01435082 ! positive regulation of growth GO:0045927 23 23 2,000 1,302E-03 0,01568302 ! cell projection assembly GO:0030031 25 23 2,000 1,302E-03 0,01558118 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 1,326E-03 0,01576992 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,326E-03 0,01566883 GO:0018409|peptide or protein amino-terminal blocking, ! cartilage condensation GO:0001502 7 6 1,000 1,326E-03 0,01556903 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,326E-03 0,01547049 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 1,000 1,326E-03 0,01537319 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,326E-03 0,01527711 ! oligodendrocyte differentiation GO:0048709 6 6 1,000 1,326E-03 0,01518222 ! focal adhesion formation GO:0048041 7 6 1,000 1,326E-03 0,0150885 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,326E-03 0,01499594 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 1,326E-03 0,0149045 ! negative regulation of ossification GO:0030279 6 6 1,000 1,326E-03 0,01481417 ! regulation of bone resorption GO:0045124 6 6 1,000 1,326E-03 0,01472493 ! purine base biosynthetic process GO:0009113 6 6 1,000 1,326E-03 0,01463675 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,326E-03 0,01454963 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,326E-03 0,01446354 ! genitalia development GO:0048806 6 6 1,000 1,326E-03 0,01437846 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,326E-03 0,01429437 ! nitric oxide metabolic process GO:0046209 6 6 1,000 1,326E-03 0,01421126 GO:0006809|nitric oxide biosynthetic process, ! thymus development GO:0048538 6 6 1,000 1,326E-03 0,01412912 ! T cell differentiation GO:0030217 24 24 2,000 1,478E-03 0,01565276 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,668E-03 0,01756498 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 1,668E-03 0,01746518 ! protein amino acid dephosphorylation GO:0006470 55 54 3,000 1,704E-03 0,01774689 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,845E-03 0,01910619 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,845E-03 0,01899945 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,845E-03 0,0188939 ! regulation of chemokine production GO:0032642 7 7 1,000 1,845E-03 0,01878951 ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,845E-03 0,01868627 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 1,845E-03 0,01858416 ! negative regulation of lipid metabolic process GO:0045833 7 7 1,000 1,845E-03 0,01848316 ! digestive system development GO:0055123 7 7 1,000 1,845E-03 0,01838325 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 1,000 1,845E-03 0,01828442 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 1,845E-03 0,01818664 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,845E-03 0,0180899 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 1,845E-03 0,01799419 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,845E-03 0,01789948 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,845E-03 0,01780577 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,845E-03 0,01771303 ! axon cargo transport GO:0008088 7 7 1,000 1,845E-03 0,01762125 ! cranial nerve development GO:0021545 7 7 1,000 1,845E-03 0,01753042 ! autonomic nervous system development GO:0048483 7 7 1,000 1,845E-03 0,01744052 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 1,845E-03 0,01735154 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,845E-03 0,01726346 ! negative regulation of cell migration GO:0030336 26 26 2,000 1,873E-03 0,01742991 ! pigment metabolic process GO:0042440 26 26 2,000 1,873E-03 0,01734233 ! extracellular structure organization GO:0043062 56 56 3,000 1,951E-03 0,01798115 ! regulation of binding GO:0051098 60 57 3,000 2,084E-03 0,01910464 ! regulation of protein localization GO:0032880 58 57 3,000 2,084E-03 0,01901006 ! cell growth GO:0016049 27 27 2,000 2,092E-03 0,01899535 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 2,092E-03 0,01890223 ! mesenchymal cell development GO:0014031 29 27 2,000 2,092E-03 0,01881003 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! regulation of cell growth GO:0001558 97 96 4,000 2,174E-03 0,0194524 ! cartilage development GO:0051216 29 28 2,000 2,327E-03 0,02072156 ! dephosphorylation GO:0016311 60 59 3,000 2,367E-03 0,02096882 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 2,445E-03 0,0215622 ! T cell selection GO:0045058 8 8 1,000 2,445E-03 0,02145953 ! phosphagen metabolic process GO:0006599 8 8 1,000 2,445E-03 0,02135782 GO:0006600|creatine metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 2,445E-03 0,02125708 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 2,445E-03 0,02115728 ! alpha-beta T cell activation GO:0046631 8 8 1,000 2,445E-03 0,02105841 ! T cell homeostasis GO:0043029 8 8 1,000 2,445E-03 0,02096047 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 2,445E-03 0,02086343 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 2,445E-03 0,02076728 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 2,445E-03 0,02067202 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 2,445E-03 0,02057763 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 2,578E-03 0,02159869 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 2,578E-03 0,02150096 ! positive regulation of protein transport GO:0051222 29 29 2,000 2,578E-03 0,0214041 ! response to UV GO:0009411 29 29 2,000 2,578E-03 0,02130812 ! hemopoiesis GO:0030097 104 100 4,000 2,601E-03 0,02139643 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 2,675E-03 0,02191061 ! morphogenesis of an epithelium GO:0002009 63 62 3,000 2,839E-03 0,02315177 GO:0060429|epithelium development, ! response to reactive oxygen species GO:0000302 31 30 2,000 2,845E-03 0,02310018 ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 2,845E-03 0,02299886 ! skeletal system morphogenesis GO:0048705 31 30 2,000 2,845E-03 0,02289843 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 3,124E-03 0,02503598 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 3,124E-03 0,0249276 ! RNA polyadenylation GO:0043631 9 9 1,000 3,124E-03 0,02482015 GO:0006378|mRNA polyadenylation, ! response to alkaloid GO:0043279 10 9 1,000 3,124E-03 0,02471363 ! response to ethanol GO:0045471 9 9 1,000 3,124E-03 0,02460801 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 3,124E-03 0,0245033 ! glutamine metabolic process GO:0006541 9 9 1,000 3,124E-03 0,02439947 ! pigmentation during development GO:0048066 9 9 1,000 3,124E-03 0,02429652 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 1,000 3,124E-03 0,02419443 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 3,124E-03 0,0240932 ! substrate-bound cell migration GO:0006929 9 9 1,000 3,124E-03 0,02399281 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 3,124E-03 0,02389326 GO:0060675|ureteric bud morphogenesis, ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 3,124E-03 0,02379453 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 3,124E-03 0,02369661 ! regulation of cellular pH GO:0030641 9 9 1,000 3,124E-03 0,02359949 ! histone acetylation GO:0016573 9 9 1,000 3,124E-03 0,02350316 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 3,124E-03 0,02340762 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 3,124E-03 0,02331286 ! regulation of leukocyte migration GO:0002685 9 9 1,000 3,124E-03 0,02321885 ! purine base metabolic process GO:0006144 9 9 1,000 3,124E-03 0,0231256 ! B cell activation GO:0042113 31 31 2,000 3,129E-03 0,02306427 ! aging GO:0007568 32 31 2,000 3,129E-03 0,02297238 ! extracellular matrix organization GO:0030198 31 31 2,000 3,129E-03 0,02288122 ! regulation of intracellular transport GO:0032386 31 31 2,000 3,129E-03 0,02279078 ! negative regulation of cell motion GO:0051271 31 31 2,000 3,129E-03 0,02270105 ! regulation of response to external stimulus GO:0032101 65 64 3,000 3,188E-03 0,02303856 ! angiogenesis GO:0001525 65 64 3,000 3,188E-03 0,02294857 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 3,429E-03 0,02458863 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 3,746E-03 0,02675947 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 3,881E-03 0,02761932 ! regulation of lipid biosynthetic process GO:0046890 10 10 1,000 3,881E-03 0,02751309 ! regulation of survival gene product expression GO:0045884 10 10 1,000 3,881E-03 0,02740768 ! epidermis morphogenesis GO:0048730 10 10 1,000 3,881E-03 0,02730307 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 3,881E-03 0,02719926 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 1,000 3,881E-03 0,02709623 ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 3,881E-03 0,02699398 ! neuromuscular junction development GO:0007528 10 10 1,000 3,881E-03 0,0268925 ! regulation of protein binding GO:0043393 11 10 1,000 3,881E-03 0,02679178 ! gland morphogenesis GO:0022612 10 10 1,000 3,881E-03 0,02669181 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 3,881E-03 0,02659258 ! lymphocyte homeostasis GO:0002260 10 10 1,000 3,881E-03 0,02649409 ! nerve development GO:0021675 10 10 1,000 3,881E-03 0,02639633 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 3,881E-03 0,02629928 ! gut development GO:0048565 10 10 1,000 3,881E-03 0,02620295 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 3,881E-03 0,02610732 ! mRNA 3'-end processing GO:0031124 10 10 1,000 3,881E-03 0,02601238 ! protein stabilization GO:0050821 10 10 1,000 3,881E-03 0,02591813 ! response to radiation GO:0009314 70 68 3,000 3,971E-03 0,02641767 ! regulation of bone remodeling GO:0046850 34 34 2,000 4,081E-03 0,02705252 ! secondary metabolic process GO:0019748 34 34 2,000 4,081E-03 0,02695556 ! wound healing GO:0042060 74 70 3,000 4,407E-03 0,02900683 ! growth GO:0040007 70 70 3,000 4,407E-03 0,0289036 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 4,433E-03 0,02897082 ! regulation of tissue remodeling GO:0034103 35 35 2,000 4,433E-03 0,02886845 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 4,715E-03 0,03059545 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 4,715E-03 0,0304881 ! signal complex assembly GO:0007172 11 11 1,000 4,715E-03 0,03038149 ! microtubule-based transport GO:0010970 11 11 1,000 4,715E-03 0,03027563 ! protein amino acid acetylation GO:0006473 11 11 1,000 4,715E-03 0,03017051 ! regulation of viral genome replication GO:0045069 11 11 1,000 4,715E-03 0,03006611 ! apoptotic nuclear changes GO:0030262 11 11 1,000 4,715E-03 0,02996244 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 4,715E-03 0,02985947 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 4,715E-03 0,02975722 ! oogenesis GO:0048477 11 11 1,000 4,715E-03 0,02965566 ! muscle maintenance GO:0046716 12 11 1,000 4,715E-03 0,02955479 ! RNA 3'-end processing GO:0031123 11 11 1,000 4,715E-03 0,0294546 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 4,715E-03 0,02935509 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 2,000 4,803E-03 0,02980454 ! regulation of transcription factor activity GO:0051090 38 37 2,000 5,191E-03 0,03210605 GO:0090046|regulation of transcription regulator activity, ! DNA damage response, signal transduction GO:0042770 37 37 2,000 5,191E-03 0,03199868 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 5,623E-03 0,03454214 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 5,623E-03 0,03442738 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 5,623E-03 0,03431338 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 5,623E-03 0,03420013 ! collagen metabolic process GO:0032963 12 12 1,000 5,623E-03 0,03408763 ! xenobiotic metabolic process GO:0006805 12 12 1,000 5,623E-03 0,03397587 ! male gonad development GO:0008584 12 12 1,000 5,623E-03 0,03386484 ! renal system process GO:0003014 12 12 1,000 5,623E-03 0,03375453 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 5,623E-03 0,03364494 ! somitogenesis GO:0001756 13 12 1,000 5,623E-03 0,03353605 ! G1 phase GO:0051318 13 12 1,000 5,623E-03 0,03342787 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 5,623E-03 0,03332039 ! positive regulation of multicellular organismal process GO:0051240 76 76 3,000 5,908E-03 0,0348981 ! lymphocyte differentiation GO:0030098 39 39 2,000 6,023E-03 0,03546688 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 6,187E-03 0,03631592 ! regulation of protein modification process GO:0031399 79 78 3,000 6,475E-03 0,0378863 ! positive regulation of protein kinase cascade GO:0010740 79 78 3,000 6,475E-03 0,0377664 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 6,604E-03 0,03839527 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 6,604E-03 0,03827453 ! regeneration GO:0031099 13 13 1,000 6,604E-03 0,03815455 ! post-embryonic development GO:0009791 14 13 1,000 6,604E-03 0,03803532 ! vasculogenesis GO:0001570 13 13 1,000 6,604E-03 0,03791683 ! negative regulation of DNA replication GO:0008156 13 13 1,000 6,604E-03 0,03779907 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 6,604E-03 0,03768205 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 6,604E-03 0,03756574 GO:0051384|response to glucocorticoid stimulus, ! receptor metabolic process GO:0043112 14 13 1,000 6,604E-03 0,03745016 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 6,604E-03 0,03733528 ! ureteric bud development GO:0001657 13 13 1,000 6,604E-03 0,0372211 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 6,604E-03 0,03710763 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 6,604E-03 0,03699484 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 1,000 6,604E-03 0,03688273 ! nucleobase metabolic process GO:0009112 13 13 1,000 6,604E-03 0,0367713 ! neural crest cell migration GO:0001755 14 13 1,000 6,604E-03 0,03666055 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 6,604E-03 0,03655045 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 6,604E-03 0,03644102 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 1,000 6,604E-03 0,03633224 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 1,000 6,604E-03 0,03622411 ! tissue homeostasis GO:0001894 13 13 1,000 6,604E-03 0,03611662 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 6,604E-03 0,03600977 ! development of primary sexual characteristics GO:0045137 42 42 2,000 7,414E-03 0,04030408 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 7,657E-03 0,04150712 ! protein amino acid acylation GO:0043543 14 14 1,000 7,657E-03 0,0413854 ! hair cycle GO:0042633 14 14 1,000 7,657E-03 0,04126439 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 7,657E-03 0,04114409 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 7,657E-03 0,04102448 ! response to retinoic acid GO:0032526 14 14 1,000 7,657E-03 0,04090557 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 1,000 7,657E-03 0,04078735 ! base-excision repair GO:0006284 14 14 1,000 7,657E-03 0,0406698 ! response to organic cyclic substance GO:0014070 15 14 1,000 7,657E-03 0,04055294 ! DNA modification GO:0006304 14 14 1,000 7,657E-03 0,04043674 ! blood vessel morphogenesis GO:0048514 84 83 3,000 8,05E-03 0,04238948 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 8,437E-03 0,04430133 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 8,781E-03 0,04597549 ! response to vitamin GO:0033273 15 15 1,000 8,781E-03 0,04584525 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 8,781E-03 0,04571575 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 8,781E-03 0,04558697 ! ovarian follicle development GO:0001541 15 15 1,000 8,781E-03 0,04545892 ! leukocyte homeostasis GO:0001776 15 15 1,000 8,781E-03 0,04533158 ! glutathione metabolic process GO:0006749 16 15 1,000 8,781E-03 0,04520495 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 8,781E-03 0,04507904 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 8,781E-03 0,04495382 GO:0090048|negative regulation of transcription regulator activity, ! regulation of DNA binding GO:0051101 47 45 2,000 8,979E-03 0,04583851 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 8,979E-03 0,04571189 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 8,979E-03 0,04558596 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 8,979E-03 0,04546072 ! heart development GO:0007507 90 87 3,000 9,477E-03 0,04785385 ! tube morphogenesis GO:0035239 47 46 2,000 9,54E-03 0,04803943 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 9,54E-03 0,04790853 ! positive regulation of ligase activity GO:0051351 47 46 2,000 9,54E-03 0,04777834 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 9,974E-03 0,04981454 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 9,974E-03 0,04967991 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 9,974E-03 0,049546 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 9,974E-03 0,04941281 ! segmentation GO:0035282 17 16 1,000 9,974E-03 0,04928034 ! triglyceride metabolic process GO:0006641 16 16 1,000 9,974E-03 0,04914857 ! iron ion homeostasis GO:0055072 16 16 1,000 9,974E-03 0,04901751 ! positive regulation of cell development GO:0010720 16 16 1,000 9,974E-03 0,04888714 ! lymphocyte proliferation GO:0046651 16 16 1,000 9,974E-03 0,04875747 ! positive regulation of catabolic process GO:0009896 16 16 1,000 9,974E-03 0,04862848 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 9,974E-03 0,04850017 ! brain development GO:0007420 91 90 3,000 0,01064969 0,05165097 ! actin filament organization GO:0007015 50 48 2,000 0,01072345 0,05187223 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 0,01072345 0,05173644 ! negative regulation of cell cycle GO:0045786 92 91 3,000 0,01106042 0,05322287 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 0,0112341 0,05391781 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 0,0112341 0,05377777 ! myelination GO:0042552 17 17 1,000 0,0112341 0,05363845 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 0,0112341 0,05349985 ! cell junction assembly GO:0034329 18 17 1,000 0,0112341 0,05336196 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 0,0112341 0,05322478 ! neural crest cell development GO:0014032 19 17 1,000 0,0112341 0,05308831 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 18 17 1,000 0,0112341 0,05295253 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 0,0112341 0,05281745 ! embryonic organ development GO:0048568 17 17 1,000 0,0112341 0,05268305 ! leukocyte differentiation GO:0002521 50 49 2,000 0,01134562 0,053071 ! skeletal muscle tissue development GO:0007519 50 49 2,000 0,01134562 0,05293664 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 2,000 0,01134562 0,05280296 ! tissue morphogenesis GO:0048729 94 93 3,000 0,01191235 0,05530093 ! T cell activation GO:0042110 51 50 2,000 0,01198828 0,05551355 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 0,01198828 0,05537442 ! regulation of neurogenesis GO:0050767 51 50 2,000 0,01198828 0,05523598 ! anatomical structure homeostasis GO:0060249 51 50 2,000 0,01198828 0,05509824 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 0,01198828 0,05496118 ! blood vessel development GO:0001568 95 94 3,000 0,01235373 0,05649608 ! regulation of cell projection organization GO:0031344 19 18 1,000 0,01256076 0,05730069 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 0,01256076 0,05715921 ! mononuclear cell proliferation GO:0032943 18 18 1,000 0,01256076 0,05701842 GO:0070661|leukocyte proliferation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 0,01256076 0,05687833 ! neutral lipid metabolic process GO:0006638 18 18 1,000 0,01256076 0,05673892 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 1,000 0,01256076 0,05660019 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 0,01256076 0,05646215 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! ensheathment of neurons GO:0007272 18 18 1,000 0,01256076 0,05632477 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 0,01256076 0,05618806 ! protein modification by small protein conjugation GO:0032446 52 51 2,000 0,01265154 0,0564571 ! vasculature development GO:0001944 97 96 3,000 0,01326771 0,05906375 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 0,0133355 0,05922248 ! cell fate commitment GO:0045165 52 52 2,000 0,0133355 0,05908012 ! response to light stimulus GO:0009416 53 52 2,000 0,0133355 0,05893844 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 0,01395236 0,06151722 ! glial cell differentiation GO:0010001 19 19 1,000 0,01395236 0,0613704 ! regulation of pH GO:0006885 19 19 1,000 0,01395236 0,06122428 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 0,01395236 0,06107886 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 0,01395236 0,06093412 ! metanephros development GO:0001656 19 19 1,000 0,01395236 0,06079007 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 0,01395236 0,0606467 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01395236 0,060504 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 0,01395236 0,06036197 ! regulation of cell shape GO:0008360 21 19 1,000 0,01395236 0,06022061 ! placenta development GO:0001890 19 19 1,000 0,01395236 0,0600799 ! response to heat GO:0009408 19 19 1,000 0,01395236 0,05993986 ! regulation of protein transport GO:0051223 53 53 2,000 0,01404026 0,06017722 GO:0070201|regulation of establishment of protein localization, ! blood circulation GO:0008015 99 98 3,000 0,01422389 0,06082282 GO:0003013|circulatory system process, ! anti-apoptosis GO:0006916 100 99 3,000 0,01471801 0,06279001 ! response to virus GO:0009615 54 54 2,000 0,0147659 0,06284886 ! sulfur metabolic process GO:0006790 55 54 2,000 0,0147659 0,06270405 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 0,0152229 0,0644961 ! regulation of muscle development GO:0048634 21 20 1,000 0,01540757 0,06512878 ! negative regulation of binding GO:0051100 21 20 1,000 0,01540757 0,06497975 ! organic ether metabolic process GO:0018904 20 20 1,000 0,01540757 0,06483139 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 0,01540757 0,06468371 ! nucleus organization GO:0006997 20 20 1,000 0,01540757 0,06453671 ! chromatin remodeling GO:0006338 20 20 1,000 0,01540757 0,06439036 ! female gamete generation GO:0007292 20 20 1,000 0,01540757 0,06424468 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 0,01540757 0,06409966 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 0,0155125 0,06439083 ! in utero embryonic development GO:0001701 55 55 2,000 0,0155125 0,06424613 ! regulation of cell adhesion GO:0030155 56 55 2,000 0,0155125 0,06410208 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 0,0155125 0,06395868 ! regulation of nervous system development GO:0051960 57 56 2,000 0,01628011 0,06697376 ! mammary gland development GO:0030879 23 21 1,000 0,01692508 0,06947198 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01692508 0,0693176 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01692508 0,0691639 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01692508 0,06901088 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01692508 0,06885854 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01692508 0,06870687 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01850359 0,07494972 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 22 22 1,000 0,01850359 0,07478536 ! odontogenesis GO:0042476 22 22 1,000 0,01850359 0,07462172 ! cell junction organization GO:0034330 23 22 1,000 0,01850359 0,07445879 ! embryonic skeletal system development GO:0048706 22 22 1,000 0,01850359 0,07429657 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01850359 0,07413505 ! ovulation cycle process GO:0022602 22 22 1,000 0,01850359 0,07397424 ! pigment biosynthetic process GO:0046148 22 22 1,000 0,01850359 0,07381412 ! biopolymer methylation GO:0043414 22 22 1,000 0,01850359 0,0736547 GO:0032259|methylation, ! regulation of cell development GO:0060284 60 59 2,000 0,01870964 0,07431438 ! immune effector process GO:0002252 59 59 2,000 0,01870964 0,07415456 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,02014185 0,0796597 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,02014185 0,07948913 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,02014185 0,07931928 ! female gonad development GO:0008585 23 23 1,000 0,02014185 0,07915015 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,02014185 0,07898175 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,02014185 0,07881406 ! axonogenesis GO:0007409 66 62 2,000 0,02133005 0,08328662 ! regulation of action potential GO:0001508 24 24 1,000 0,02183858 0,08509196 ! gliogenesis GO:0042063 24 24 1,000 0,02183858 0,08491244 ! nucleotide catabolic process GO:0009166 24 24 1,000 0,02183858 0,08473368 ! ovulation cycle GO:0042698 24 24 1,000 0,02183858 0,08455567 ! maintenance of protein location GO:0045185 25 24 1,000 0,02183858 0,0843784 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,02183858 0,08420188 ! glucan metabolic process GO:0044042 25 24 1,000 0,02183858 0,08402609 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! cellular component disassembly GO:0022411 26 25 1,000 0,02359255 0,09058557 ! endosome transport GO:0016197 25 25 1,000 0,02359255 0,09039724 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,02359255 0,0902097 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,02359255 0,09002293 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,02359255 0,08983693 ! heart morphogenesis GO:0003007 25 25 1,000 0,02359255 0,0896517 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,02359255 0,08946723 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,02359255 0,08928352 ! positive regulation of cytokine production GO:0001819 25 25 1,000 0,02359255 0,08910056 ! positive regulation of binding GO:0051099 27 26 1,000 0,02540255 0,09574009 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,02540255 0,0955447 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,02540255 0,09535011 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,02540255 0,09515631 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,02540255 0,09496329 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,02540255 0,09477106 ! double-strand break repair GO:0006302 27 26 1,000 0,02540255 0,0945796 ! germ cell development GO:0007281 27 26 1,000 0,02540255 0,09438892 ! maintenance of location in cell GO:0051651 27 26 1,000 0,02540255 0,094199 ! synapse organization GO:0050808 26 26 1,000 0,02540255 0,09400985 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,02612299 0,0964823 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 0,02612299 0,09628934 ! Ras protein signal transduction GO:0007265 69 67 2,000 0,02612299 0,09609714 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,02726737 0,10010711 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,02726737 0,09990809 ! peptide metabolic process GO:0006518 29 27 1,000 0,02726737 0,09970986 ! activation of caspase activity GO:0006919 27 27 1,000 0,02726737 0,09951242 ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 0,02726737 0,09931575 ! regionalization GO:0003002 70 69 2,000 0,02818907 0,10247033 ! histone modification GO:0016570 28 28 1,000 0,02918584 0,10588483 ! developmental growth GO:0048589 28 28 1,000 0,02918584 0,10567681 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,02918584 0,1054696 ! positive regulation of transport GO:0051050 71 70 2,000 0,02925395 0,10550885 ! cell part morphogenesis GO:0032990 75 70 2,000 0,02925395 0,10530277 ! muscle tissue development GO:0060537 72 70 2,000 0,02925395 0,10509751 ! regulation of cell activation GO:0050865 71 71 2,000 0,03034 0,10878719 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,03115677 0,11149888 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,03115677 0,1112828 ! covalent chromatin modification GO:0016569 29 29 1,000 0,03115677 0,11106755 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,03317902 0,11804814 GO:0043280|positive regulation of caspase activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,03317902 0,11782069 ! response to temperature stimulus GO:0009266 30 30 1,000 0,03317902 0,11759411 ! regulation of ossification GO:0030278 30 30 1,000 0,03317902 0,1173684 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,03317902 0,11714356 ! vesicle organization GO:0016050 30 30 1,000 0,03317902 0,11691957 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,03525146 0,12398558 ! nucleoside metabolic process GO:0009116 31 31 1,000 0,03525146 0,12374942 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,03525146 0,12351415 ! muscle fiber development GO:0048747 32 32 1,000 0,03737297 0,13069903 ! cell maturation GO:0048469 32 32 1,000 0,03737297 0,13045149 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,03737297 0,13020489 ! kidney development GO:0001822 32 32 1,000 0,03737297 0,12995922 ! maintenance of location GO:0051235 33 32 1,000 0,03737297 0,12971448 ! amino acid transport GO:0006865 33 33 1,000 0,03954245 0,13698635 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,03954245 0,13672934 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,03954245 0,1364733 ! neuron projection development GO:0031175 85 80 2,000 0,04105939 0,14144385 ! response to metal ion GO:0010038 34 34 1,000 0,04175882 0,14358489 ! ear development GO:0043583 34 34 1,000 0,04175882 0,1433175 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,04175882 0,14305111 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,04175882 0,14278571 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,04175882 0,14252129 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,04175882 0,14225785 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,04175882 0,14199539 ! lymphocyte activation GO:0046649 82 81 2,000 0,04235425 0,14375486 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,044021 0,14913731 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,044021 0,14886366 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,044021 0,14859102 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,044021 0,14831937 ! response to inorganic substance GO:0010035 36 36 1,000 0,04632794 0,15580727 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,04632794 0,15552347 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,04632794 0,1552407 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,04632794 0,15495896 ! gonad development GO:0008406 36 36 1,000 0,04632794 0,15467823 ! coagulation GO:0050817 39 36 1,000 0,04632794 0,15439853 GO:0007596|blood coagulation, ! cellular amino acid derivative metabolic process GO:0006575 87 84 2,000 0,04636135 0,154231 ! rRNA transcription GO:0009303 5 5 0,000 0,04706706 0,15629657 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04706706 0,15601546 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04706706 0,15573536 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04706706 0,15545627 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04706706 0,15517817 ! reproductive cellular process GO:0048610 5 5 0,000 0,04706706 0,15490107 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04706706 0,15462495 ! water transport GO:0006833 5 5 0,000 0,04706706 0,15434982 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04706706 0,15407566 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04706706 0,15380248 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04706706 0,15353026 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04706706 0,15325901 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04706706 0,15298871 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04706706 0,15271936 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04706706 0,15245096 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04706706 0,1521835 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04706706 0,15191698 ! filopodium assembly GO:0046847 7 5 0,000 0,04706706 0,15165139 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04706706 0,15138673 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04706706 0,15112299 ! GTP metabolic process GO:0046039 5 5 0,000 0,04706706 0,15086017 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04706706 0,15059826 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04706706 0,15033726 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04706706 0,15007716 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04706706 0,14981796 ! social behavior GO:0035176 5 5 0,000 0,04706706 0,14955965 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04706706 0,14930223 ! memory GO:0007613 5 5 0,000 0,04706706 0,1490457 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04706706 0,14879005 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04706706 0,14853527 ! response to lipid GO:0033993 5 5 0,000 0,04706706 0,14828136 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04706706 0,14802832 ! hippocampus development GO:0021766 6 5 0,000 0,04706706 0,14777614 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04706706 0,14752482 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04706706 0,14727436 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04706706 0,14702474 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04706706 0,14677597 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04706706 0,14652804 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04706706 0,14628094 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04706706 0,14603467 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04706706 0,14578924 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04706706 0,14554463 ! pH reduction GO:0045851 5 5 0,000 0,04706706 0,14530083 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04706706 0,14505785 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04706706 0,14481569 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04706706 0,14457433 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04706706 0,14433377 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04706706 0,14409401 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04706706 0,14385505 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04706706 0,14361688 ! adrenal gland development GO:0030325 5 5 0,000 0,04706706 0,1433795 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04706706 0,1431429 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04706706 0,14290708 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04706706 0,14267203 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04706706 0,14243776 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04706706 0,14220426 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04706706 0,14197152 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04706706 0,14173954 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04706706 0,14150831 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04706706 0,14127785 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04706706 0,14104813 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04706706 0,14081915 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04706706 0,14059092 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04706706 0,14036343 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04706706 0,14013667 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04706706 0,13991064 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04706706 0,13968534 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04706706 0,13946077 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04706706 0,13923691 ! response to ATP GO:0033198 5 5 0,000 0,04706706 0,13901378 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04706706 0,13879136 ! regulation of appetite GO:0032098 5 5 0,000 0,04706706 0,13856964 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04706706 0,13834864 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04706706 0,13812834 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,04706706 0,13790874 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04706706 0,13768984 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04706706 0,13747163 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04706706 0,13725411 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04706706 0,13703728 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04706706 0,13682113 ! retinol metabolic process GO:0042572 5 5 0,000 0,04706706 0,13660566 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04706706 0,13639088 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04706706 0,13617676 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04706706 0,13596332 ! parturition GO:0007567 5 5 0,000 0,04706706 0,13575054 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04706706 0,13553843 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04706706 0,13532698 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04706706 0,13511619 ! protein heterooligomerization GO:0051291 5 5 0,000 0,04706706 0,13490606 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04706706 0,13469658 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04706706 0,13448775 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04706706 0,13427956 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04706706 0,13407202 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04706706 0,13386512 ! interaction with symbiont GO:0051702 5 5 0,000 0,04706706 0,13365886 ! cellular extravasation GO:0045123 5 5 0,000 0,04706706 0,13345323 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04706706 0,13324823 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04706706 0,13304386 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04706706 0,13284012 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04706706 0,132637 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04706706 0,1324345 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,04706706 0,13223262 ! response to amine stimulus GO:0014075 5 5 0,000 0,04706706 0,13203135 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04706706 0,13183069 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04706706 0,13163065 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04706706 0,13143121 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04706706 0,13123237 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04706706 0,13103413 ! neuron recognition GO:0008038 5 5 0,000 0,04706706 0,1308365 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04706706 0,13063945 ! decidualization GO:0046697 5 5 0,000 0,04706706 0,130443 ! hair follicle maturation GO:0048820 5 5 0,000 0,04706706 0,13024714 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04706706 0,13005187 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04706706 0,12985718 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04706706 0,12966307 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04706706 0,12946955 ! postreplication repair GO:0006301 5 5 0,000 0,04706706 0,1292766 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04706706 0,12908422 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,04706706 0,12889242 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04706706 0,12870118 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04706706 0,12851051 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04706706 0,12832041 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04706706 0,12813087 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04706706 0,12794188 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04706706 0,12775346 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04706706 0,12756558 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04706706 0,12737826 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04706706 0,12719149 ! sterol catabolic process GO:0016127 5 5 0,000 0,04706706 0,12700527 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04706706 0,12681959 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04706706 0,12663445 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04706706 0,12644985 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04706706 0,12626579 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04706706 0,12608226 ! zymogen activation GO:0031638 5 5 0,000 0,04706706 0,12589927 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04706706 0,12571681 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04706706 0,12553487 GO:0002820|negative regulation of adaptive immune response, ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04706706 0,12535346 ! nucleosome positioning GO:0016584 5 5 0,000 0,04706706 0,12517258 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04706706 0,12499221 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04706706 0,12481237 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04706706 0,12463304 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04706706 0,12445423 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04706706 0,12427593 ! NADPH regeneration GO:0006740 5 5 0,000 0,04706706 0,12409814 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04706706 0,12392085 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04706706 0,12374408 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04706706 0,1235678 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04706706 0,12339203 ! sarcomere organization GO:0045214 5 5 0,000 0,04706706 0,12321676 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04706706 0,12304198 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04706706 0,1228677 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04706706 0,12269391 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04706706 0,12252062 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04706706 0,12234781 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04706706 0,12217549 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04706706 0,12200365 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04706706 0,1218323 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04706706 0,12166143 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04706706 0,12149103 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04706706 0,12132111 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04706706 0,12115167 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04706706 0,1209827 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04706706 0,1208142 ! ATP catabolic process GO:0006200 5 5 0,000 0,04706706 0,12064617 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04706706 0,12047861 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04706706 0,12031151 ! blastocyst formation GO:0001825 5 5 0,000 0,04706706 0,12014487 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04706706 0,1199787 ! embryonic gut development GO:0048566 5 5 0,000 0,04706706 0,11981298 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04706706 0,11964772 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04706706 0,11948292 ! activation of innate immune response GO:0002218 5 5 0,000 0,04706706 0,11931857 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,04706706 0,11915467 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04706706 0,11899122 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04706706 0,11882821 ! muscle adaptation GO:0043500 5 5 0,000 0,04706706 0,11866566 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04706706 0,11850355 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04706706 0,11834188 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04706706 0,11818065 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04706706 0,11801986 ! defense response to fungus GO:0050832 5 5 0,000 0,04706706 0,11785951 ! lysogeny GO:0030069 5 5 0,000 0,04706706 0,11769959 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04706706 0,1175401 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04706706 0,11738105 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04706706 0,11722243 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04706706 0,11706423 ! mitochondrion localization GO:0051646 5 5 0,000 0,04706706 0,11690646 ! nucleus localization GO:0051647 5 5 0,000 0,04706706 0,11674912 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04706706 0,1165922 ! regulation of cellular localization GO:0060341 86 85 2,000 0,04773758 0,11809443 ! nitrogen compound biosynthetic process GO:0044271 86 85 2,000 0,04773758 0,11793613 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,04773758 0,11777825 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,04773758 0,11762079 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,0486786 0,11977925 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! adaptive immune response GO:0002250 37 37 1,000 0,0486786 0,11961955 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! meiotic cell cycle GO:0051321 38 38 1,000 0,05107196 0,12533373 ! axon guidance GO:0007411 39 38 1,000 0,05107196 0,12516706 ! male gamete generation GO:0048232 90 88 2,000 0,05198639 0,12723893 GO:0007283|spermatogenesis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 2,000 0,05344235 0,13062897 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,05350702 0,13061383 ! hemostasis GO:0007599 42 39 1,000 0,05350702 0,13044106 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,05350702 0,13026875 ! activation of MAPK activity GO:0000187 39 39 1,000 0,05350702 0,13009689 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,05350702 0,12992548 ! fatty acid biosynthetic process GO:0006633 39 39 1,000 0,05350702 0,12975453 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,05350702 0,12958402 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,05350702 0,12941396 ! developmental maturation GO:0021700 39 39 1,000 0,05350702 0,12924435 ! protein oligomerization GO:0051259 39 39 1,000 0,05350702 0,12907518 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,05598278 0,13487093 ! DNA catabolic process GO:0006308 41 40 1,000 0,05598278 0,13469486 ! axon extension GO:0048675 7 6 0,000 0,05621522 0,13507777 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,05621522 0,13490189 ! tRNA modification GO:0006400 6 6 0,000 0,05621522 0,13472646 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,05621522 0,13455149 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,05621522 0,13437698 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,05621522 0,13420291 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,05621522 0,1340293 ! virus-host interaction GO:0019048 6 6 0,000 0,05621522 0,13385614 ! regulation of S phase GO:0033261 6 6 0,000 0,05621522 0,13368342 ! myotube differentiation GO:0014902 6 6 0,000 0,05621522 0,13351115 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,05621522 0,13333932 ! bone remodeling GO:0046849 6 6 0,000 0,05621522 0,13316793 ! N-glycan processing GO:0006491 6 6 0,000 0,05621522 0,13299698 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,05621522 0,13282647 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,05621522 0,1326564 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,05621522 0,13248676 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,05621522 0,13231756 ! RNA methylation GO:0001510 6 6 0,000 0,05621522 0,13214879 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,05621522 0,13198044 ! artery development GO:0060840 6 6 0,000 0,05621522 0,13181253 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,05621522 0,13164504 ! bile acid metabolic process GO:0008206 6 6 0,000 0,05621522 0,13147798 ! androgen metabolic process GO:0008209 6 6 0,000 0,05621522 0,13131134 ! estrogen metabolic process GO:0008210 6 6 0,000 0,05621522 0,13114513 ! limbic system development GO:0021761 7 6 0,000 0,05621522 0,13097933 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,05621522 0,13081395 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,05621522 0,13064899 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,05621522 0,13048444 ! pathogenesis GO:0009405 6 6 0,000 0,05621522 0,13032031 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,05621522 0,13015659 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,05621522 0,12999329 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,05621522 0,12983039 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,05621522 0,1296679 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,05621522 0,12950581 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,05621522 0,12934413 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,05621522 0,12918285 ! arginine metabolic process GO:0006525 6 6 0,000 0,05621522 0,12902198 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,05621522 0,1288615 ! glutamate catabolic process GO:0006538 7 6 0,000 0,05621522 0,12870143 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,05621522 0,12854175 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,05621522 0,12838246 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,05621522 0,12822358 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,05621522 0,12806508 ! V(D)J recombination GO:0033151 6 6 0,000 0,05621522 0,12790697 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,05621522 0,12774926 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,05621522 0,12759193 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,05621522 0,12743499 ! regulation of heart rate GO:0002027 6 6 0,000 0,05621522 0,12727844 ! lipid digestion GO:0044241 6 6 0,000 0,05621522 0,12712227 ! asymmetric protein localization GO:0008105 6 6 0,000 0,05621522 0,12696648 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,05621522 0,12681108 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,05621522 0,12665605 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,05621522 0,1265014 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,05621522 0,12634713 ! ruffle organization GO:0031529 6 6 0,000 0,05621522 0,12619324 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,05621522 0,12603972 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,05621522 0,12588657 ! neutral amino acid transport GO:0015804 6 6 0,000 0,05621522 0,1257338 ! L-amino acid transport GO:0015807 6 6 0,000 0,05621522 0,12558139 ! bone mineralization GO:0030282 6 6 0,000 0,05621522 0,12542936 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,05621522 0,12527769 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,05621522 0,12512639 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,05621522 0,12497545 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,05621522 0,12482488 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,05621522 0,12467467 ! regulation of organ growth GO:0046620 6 6 0,000 0,05621522 0,12452482 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,05621522 0,12437533 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,05621522 0,1242262 ! response to dsRNA GO:0043331 6 6 0,000 0,05621522 0,12407742 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,05621522 0,12392901 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,05621522 0,12378094 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,05621522 0,12363323 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,05621522 0,12348587 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,05621522 0,12333887 ! multicellular organismal aging GO:0010259 6 6 0,000 0,05621522 0,12319221 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,05621522 0,1230459 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,05621522 0,12289994 ! erythrocyte development GO:0048821 6 6 0,000 0,05621522 0,12275432 ! renal water homeostasis GO:0003091 6 6 0,000 0,05621522 0,12260905 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,05621522 0,12246412 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,05621522 0,12231954 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,05621522 0,12217529 ! ribosome assembly GO:0042255 6 6 0,000 0,05621522 0,12203139 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,05621522 0,12188782 ! diencephalon development GO:0021536 6 6 0,000 0,05621522 0,12174459 ! fucose catabolic process GO:0019317 6 6 0,000 0,05621522 0,1216017 GO:0042355|L-fucose catabolic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,05621522 0,12145914 ! regulation of cell division GO:0051302 6 6 0,000 0,05621522 0,12131692 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,05621522 0,12117503 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,05621522 0,12103347 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,05621522 0,12089224 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,05621522 0,12075134 ! neuroblast proliferation GO:0007405 6 6 0,000 0,05621522 0,12061077 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,05621522 0,12047052 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,05621522 0,1203306 ! regulation of glucose transport GO:0010827 6 6 0,000 0,05621522 0,12019101 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,05621522 0,12005174 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,05621522 0,11991279 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,05621522 0,11977416 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,05621522 0,11963585 ! lymph node development GO:0048535 6 6 0,000 0,05621522 0,11949786 ! organic cation transport GO:0015695 6 6 0,000 0,05621522 0,11936019 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,05621522 0,11922284 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,05621522 0,1190858 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,05621522 0,11894908 ! sperm-egg recognition GO:0035036 7 6 0,000 0,05621522 0,11881267 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,05621522 0,11867657 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,05621522 0,11854079 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,05621522 0,11840531 ! alditol metabolic process GO:0019400 6 6 0,000 0,05621522 0,11827015 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,05621522 0,11813529 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,05621522 0,11800074 ! maternal placenta development GO:0001893 6 6 0,000 0,05621522 0,11786649 ! regulation of embryonic development GO:0045995 6 6 0,000 0,05621522 0,11773256 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,05621522 0,11759892 ! localization within membrane GO:0051668 6 6 0,000 0,05621522 0,11746559 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 2,000 0,0564131 0,11774557 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,05792765 0,12076998 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,05849826 0,1218218 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 0,05849826 0,1216843 ! regulation of response to stress GO:0080134 97 94 2,000 0,0610145 0,12677534 ! pattern specification process GO:0007389 96 94 2,000 0,0610145 0,12663257 ! epidermis development GO:0008544 94 94 2,000 0,0610145 0,12649013 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,0610525 0,12642669 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,0610525 0,12628479 ! response to protein stimulus GO:0051789 42 42 1,000 0,0610525 0,12614322 ! forebrain development GO:0030900 43 42 1,000 0,0610525 0,12600196 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,0610525 0,12586102 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,0610525 0,12572039 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,06364454 0,13091171 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,06364454 0,13076577 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,06364454 0,13062015 ! respiratory burst GO:0045730 7 7 0,000 0,06527687 0,13382122 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,06527687 0,13367253 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,06527687 0,13352417 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,06527687 0,13337613 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,06527687 0,13322843 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,06527687 0,13308105 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,06527687 0,132934 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,06527687 0,13278728 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,06527687 0,13264087 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,06527687 0,13249479 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,06527687 0,13234904 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,06527687 0,1322036 ! axis specification GO:0009798 7 7 0,000 0,06527687 0,13205848 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,06527687 0,13191368 ! visual behavior GO:0007632 7 7 0,000 0,06527687 0,13176919 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,06527687 0,13162503 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,06527687 0,13148117 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,06527687 0,13133763 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,06527687 0,13119441 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,06527687 0,1310515 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,06527687 0,13090889 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,06527687 0,1307666 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,06527687 0,13062462 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,06527687 0,13048294 ! protein targeting to ER GO:0045047 8 7 0,000 0,06527687 0,13034157 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,06527687 0,13020051 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,06527687 0,13005975 ! endoderm development GO:0007492 7 7 0,000 0,06527687 0,1299193 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,06527687 0,12977915 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,06527687 0,1296393 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,06527687 0,12949976 ! response to hexose stimulus GO:0009746 7 7 0,000 0,06527687 0,12936051 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,06527687 0,12922156 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,06527687 0,12908291 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,06527687 0,12894456 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,06527687 0,1288065 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,06527687 0,12866874 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,06527687 0,12853127 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,06527687 0,1283941 ! UV protection GO:0009650 7 7 0,000 0,06527687 0,12825722 ! DNA integration GO:0015074 7 7 0,000 0,06527687 0,12812063 ! myofibril assembly GO:0030239 7 7 0,000 0,06527687 0,12798433 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,06527687 0,12784832 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,06527687 0,1277126 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,06527687 0,12757717 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,06527687 0,12744203 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,06527687 0,12730717 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,06527687 0,12717259 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,06527687 0,1270383 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,06527687 0,1269043 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,06527687 0,12677057 ! eating behavior GO:0042755 7 7 0,000 0,06527687 0,12663713 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,06527687 0,12650397 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,06527687 0,12637109 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,06527687 0,12623848 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,06527687 0,12610616 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,06527687 0,12597411 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,06527687 0,12584234 ! induction of an organ GO:0001759 7 7 0,000 0,06527687 0,12571084 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,06527687 0,12557962 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,06527687 0,12544867 ! intracellular lipid transport GO:0032365 7 7 0,000 0,06527687 0,12531799 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,06527687 0,12518759 ! platelet activation GO:0030168 8 7 0,000 0,06527687 0,12505746 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,06527687 0,12492759 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,06527687 0,124798 ! natural killer cell activation GO:0030101 7 7 0,000 0,06527687 0,12466868 ! NADP metabolic process GO:0006739 7 7 0,000 0,06527687 0,12453962 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,06527687 0,12441083 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,06527687 0,12428231 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,06527687 0,12415405 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,06527687 0,12402605 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,06527687 0,12389832 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,06527687 0,12377086 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,06527687 0,12364365 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,06527687 0,12351671 ! cell-cell recognition GO:0009988 8 7 0,000 0,06527687 0,12339002 ! hormone catabolic process GO:0042447 7 7 0,000 0,06527687 0,1232636 ! dopamine metabolic process GO:0042417 7 7 0,000 0,06527687 0,12313743 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,06527687 0,12301153 ! oxygen transport GO:0015671 7 7 0,000 0,06527687 0,12288588 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,06527687 0,12276048 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,06527687 0,12263534 ! regulation of axon extension GO:0030516 7 7 0,000 0,06527687 0,12251046 ! cell killing GO:0001906 7 7 0,000 0,06527687 0,12238583 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,06527687 0,12226146 ! adult feeding behavior GO:0008343 7 7 0,000 0,06527687 0,12213733 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,06527687 0,12201346 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,06527687 0,12188984 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,06527687 0,12176647 ! response to cold GO:0009409 7 7 0,000 0,06527687 0,12164335 ! humoral immune response GO:0006959 44 44 1,000 0,06627346 0,12337575 ! protein import into nucleus GO:0006606 44 44 1,000 0,06627346 0,12325126 ! endocytosis GO:0006897 99 98 2,000 0,06741547 0,12524869 GO:0010324|membrane invagination, ! nuclear import GO:0051170 45 45 1,000 0,06893834 0,127949 ! ectoderm development GO:0007398 99 99 2,000 0,06906226 0,12805005 ! response to hormone stimulus GO:0009725 102 100 2,000 0,0707274 0,13100562 ! muscle organ development GO:0007517 102 100 2,000 0,0707274 0,13087409 ! response to other organism GO:0051707 101 100 2,000 0,0707274 0,13074282 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,07163826 0,1322939 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,07163826 0,13216147 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,07163826 0,13202931 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,07425282 0,13671124 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,07425282 0,13657481 ! positive regulation of translation GO:0045727 8 8 0,000 0,07425282 0,13643864 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,07425282 0,13630274 ! superoxide anion generation GO:0042554 8 8 0,000 0,07425282 0,13616712 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,07425282 0,13603176 ! cGMP metabolic process GO:0046068 8 8 0,000 0,07425282 0,13589668 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,07425282 0,13576186 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,07425282 0,13562731 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,07425282 0,13549302 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,07425282 0,13535901 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,07425282 0,13522525 ! zinc ion transport GO:0006829 8 8 0,000 0,07425282 0,13509176 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,07425282 0,13495854 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,07425282 0,13482557 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,07425282 0,13469287 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,07425282 0,13456043 ! lipid localization GO:0010876 8 8 0,000 0,07425282 0,13442825 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,07425282 0,13429632 ! response to cAMP GO:0051591 8 8 0,000 0,07425282 0,13416466 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,07425282 0,13403326 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,07425282 0,13390211 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,07425282 0,13377122 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,07425282 0,13364058 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,07425282 0,1335102 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,07425282 0,13338007 ! sensory perception of taste GO:0050909 8 8 0,000 0,07425282 0,1332502 ! organelle fusion GO:0048284 8 8 0,000 0,07425282 0,13312058 ! pancreas development GO:0031016 8 8 0,000 0,07425282 0,13299121 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,07425282 0,13286209 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,07425282 0,13273323 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,07425282 0,13260461 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,07425282 0,13247624 ! sperm motility GO:0030317 8 8 0,000 0,07425282 0,13234812 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,07425282 0,13222025 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,07425282 0,13209262 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,07425282 0,13196524 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,07425282 0,13183811 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,07425282 0,13171122 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,07425282 0,13158457 ! Golgi organization GO:0007030 8 8 0,000 0,07425282 0,13145817 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,07425282 0,13133201 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,07425282 0,13120609 ! fructose metabolic process GO:0006000 8 8 0,000 0,07425282 0,13108042 ! mannose metabolic process GO:0006013 9 8 0,000 0,07425282 0,13095498 ! NAD metabolic process GO:0019674 8 8 0,000 0,07425282 0,13082979 ! sex determination GO:0007530 8 8 0,000 0,07425282 0,13070483 ! plasma membrane fusion GO:0045026 8 8 0,000 0,07425282 0,13058011 ! response to fungus GO:0009620 8 8 0,000 0,07425282 0,13045563 ! stem cell differentiation GO:0048863 8 8 0,000 0,07425282 0,13033139 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,07425282 0,13020738 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,07425282 0,13008361 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,07425282 0,12996007 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,07425282 0,12983677 ! regulation of vasodilation GO:0042312 8 8 0,000 0,07425282 0,1297137 ! vasoconstriction GO:0042310 8 8 0,000 0,07425282 0,12959087 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,07425282 0,12946826 ! muscle cell development GO:0055001 8 8 0,000 0,07425282 0,12934589 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,07425282 0,12922375 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,07425282 0,12910184 ! sensory perception of pain GO:0019233 8 8 0,000 0,07425282 0,12898017 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,07425282 0,12885871 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,07425282 0,12873749 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,07425282 0,1286165 ! chromatin silencing GO:0006342 8 8 0,000 0,07425282 0,12849573 ! tissue regeneration GO:0042246 8 8 0,000 0,07425282 0,12837519 ! salivary gland development GO:0007431 8 8 0,000 0,07425282 0,12825488 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,07425282 0,12813479 ! water homeostasis GO:0030104 8 8 0,000 0,07425282 0,12801493 ! cofactor transport GO:0051181 8 8 0,000 0,07425282 0,12789529 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,07425282 0,12777587 ! acid secretion GO:0046717 8 8 0,000 0,07425282 0,12765667 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,07425282 0,1275377 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,07425282 0,12741895 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,07425282 0,12730042 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,07425282 0,12718211 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,07425282 0,12706403 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,07425282 0,12694616 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,07425282 0,1268285 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,07425282 0,12671107 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,07425282 0,12659385 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,07425282 0,12647685 ! developmental induction GO:0031128 8 8 0,000 0,07425282 0,12636007 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,07425282 0,1262435 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,07425282 0,12612715 ! actin filament polymerization GO:0030041 9 8 0,000 0,07425282 0,12601101 ! peptide hormone processing GO:0016486 8 8 0,000 0,07425282 0,12589508 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,07425282 0,12577937 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,07425282 0,12566387 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,07437233 0,12575064 ! amine transport GO:0015837 47 47 1,000 0,07437233 0,12563538 ! rhythmic process GO:0048511 47 47 1,000 0,07437233 0,12552033 ! protein localization in nucleus GO:0034504 48 48 1,000 0,07713967 0,13007174 ! DNA recombination GO:0006310 48 48 1,000 0,07713967 0,12995284 ! ossification GO:0001503 50 49 1,000 0,07993942 0,13454643 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,07993942 0,13442367 ! negative regulation of transport GO:0051051 51 50 1,000 0,08277071 0,13905782 ! lactation GO:0007595 10 9 0,000 0,08314388 0,13955753 ! embryonic pattern specification GO:0009880 10 9 0,000 0,08314388 0,13943054 ! positive regulation of cell size GO:0045793 9 9 0,000 0,08314388 0,13930379 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,08314388 0,13917726 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,08314388 0,13905097 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,08314388 0,1389249 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,08314388 0,13879906 ! viral genome replication GO:0019079 9 9 0,000 0,08314388 0,13867345 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,08314388 0,13854807 ! copper ion transport GO:0006825 9 9 0,000 0,08314388 0,13842291 ! lipid phosphorylation GO:0046834 9 9 0,000 0,08314388 0,13829798 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,08314388 0,13817328 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,08314388 0,1380488 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,08314388 0,13792454 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,08314388 0,13780051 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,08314388 0,1376767 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,08314388 0,13755311 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,08314388 0,13742974 ! phospholipid efflux GO:0033700 9 9 0,000 0,08314388 0,1373066 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,08314388 0,13718368 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,08314388 0,13706097 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,08314388 0,13693849 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,08314388 0,13681622 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,08314388 0,13669417 ! methionine metabolic process GO:0006555 9 9 0,000 0,08314388 0,13657234 ! cerebral cortex development GO:0021987 9 9 0,000 0,08314388 0,13645073 ! response to osmotic stress GO:0006970 9 9 0,000 0,08314388 0,13632933 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,08314388 0,13620815 ! central nervous system neuron development GO:0021954 10 9 0,000 0,08314388 0,13608718 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,08314388 0,13596643 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,08314388 0,13584589 ! L-glutamate transport GO:0015813 9 9 0,000 0,08314388 0,13572557 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,08314388 0,13560546 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,08314388 0,13548556 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,08314388 0,13536587 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,08314388 0,13524639 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,08314388 0,13512713 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,08314388 0,13500807 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,08314388 0,13488923 ! DNA replication initiation GO:0006270 9 9 0,000 0,08314388 0,13477059 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,08314388 0,13465217 GO:0006692|prostanoid metabolic process, ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,08314388 0,13453395 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,08314388 0,13441593 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,08314388 0,13429813 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,08314388 0,13418053 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,08314388 0,13406314 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,08314388 0,13394595 ! collagen catabolic process GO:0030574 9 9 0,000 0,08314388 0,13382897 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,08314388 0,13371219 ! gas transport GO:0015669 9 9 0,000 0,08314388 0,13359561 ! cholesterol efflux GO:0033344 9 9 0,000 0,08314388 0,13347924 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,08314388 0,13336307 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,08314388 0,1332471 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,08314388 0,13313133 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,08314388 0,13301577 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,08314388 0,1329004 ! actin filament-based movement GO:0030048 9 9 0,000 0,08314388 0,13278524 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,08314388 0,13267027 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,08852461 0,14113396 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,08852461 0,14101198 ! regulation of T cell activation GO:0050863 53 53 1,000 0,09144557 0,14553901 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,09195082 0,14621688 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,09195082 0,14609083 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,09195082 0,145965 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,09195082 0,14583938 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,09195082 0,14571398 ! neuron maturation GO:0042551 10 10 0,000 0,09195082 0,1455888 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,09195082 0,14546383 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,09195082 0,14533907 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,09195082 0,14521453 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,09195082 0,14509021 ! hormone secretion GO:0046879 10 10 0,000 0,09195082 0,14496609 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,09195082 0,14484219 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,09195082 0,1447185 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,09195082 0,14459502 ! inositol metabolic process GO:0006020 10 10 0,000 0,09195082 0,14447175 ! cAMP metabolic process GO:0046058 10 10 0,000 0,09195082 0,14434869 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,09195082 0,14422584 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,09195082 0,1441032 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,09195082 0,14398077 ! glial cell development GO:0021782 10 10 0,000 0,09195082 0,14385854 ! phototransduction GO:0007602 11 10 0,000 0,09195082 0,14373652 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,09195082 0,14361471 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,09195082 0,14349311 ! fat cell differentiation GO:0045444 10 10 0,000 0,09195082 0,14337171 ! myoblast differentiation GO:0045445 10 10 0,000 0,09195082 0,14325052 ! centrosome cycle GO:0007098 10 10 0,000 0,09195082 0,14312953 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,09195082 0,14300874 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,09195082 0,14288816 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,09195082 0,14276778 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,09195082 0,14264761 ! protein polyubiquitination GO:0000209 10 10 0,000 0,09195082 0,14252764 ! glutamate metabolic process GO:0006536 11 10 0,000 0,09195082 0,14240787 ! plasma membrane organization GO:0007009 10 10 0,000 0,09195082 0,1422883 ! lysosomal transport GO:0007041 10 10 0,000 0,09195082 0,14216893 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,09195082 0,14204976 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,09195082 0,14193079 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,09195082 0,14181202 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,09195082 0,14169345 ! exocrine system development GO:0035272 10 10 0,000 0,09195082 0,14157507 ! embryo implantation GO:0007566 11 10 0,000 0,09195082 0,1414569 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,09195082 0,14133892 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,09195082 0,14122113 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,09195082 0,14110355 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,09195082 0,14098616 ! protein export from nucleus GO:0006611 10 10 0,000 0,09195082 0,14086896 ! negative regulation of immune response GO:0050777 10 10 0,000 0,09195082 0,14075196 ! cytolysis GO:0019835 10 10 0,000 0,09195082 0,14063515 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,09195082 0,14051854 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,09195082 0,14040212 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,09195082 0,14028589 ! histone deacetylation GO:0016575 10 10 0,000 0,09195082 0,14016986 ! mRNA splice site selection GO:0006376 11 10 0,000 0,09195082 0,14005402 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,09195082 0,13993837 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,09195082 0,1398229 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,09195082 0,13970763 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,09195082 0,13959255 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,09195082 0,13947766 ! regulation of epidermis development GO:0045682 10 10 0,000 0,09195082 0,13936296 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,09195082 0,13924845 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,09195082 0,13913412 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,09195082 0,13901998 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,09195082 0,13890603 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,09195082 0,13879227 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,09195082 0,13867869 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,09195082 0,1385653 ! hormone metabolic process GO:0042445 55 54 1,000 0,09439478 0,14213201 ! protein secretion GO:0009306 11 11 0,000 0,10067444 0,15146366 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,10067444 0,15134012 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,10067444 0,15121678 ! negative regulation of defense response GO:0031348 11 11 0,000 0,10067444 0,15109364 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,10067444 0,1509707 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,10067444 0,15084796 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,10067444 0,15072542 ! skin development GO:0043588 11 11 0,000 0,10067444 0,15060307 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,10067444 0,15048093 ! endothelial cell migration GO:0043542 11 11 0,000 0,10067444 0,15035898 ! peroxisomal transport GO:0043574 11 11 0,000 0,10067444 0,15023724 ! protein amino acid methylation GO:0006479 11 11 0,000 0,10067444 0,15011568 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,10067444 0,14999433 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,10067444 0,14987317 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,10067444 0,14975221 ! T cell proliferation GO:0042098 11 11 0,000 0,10067444 0,14963144 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,10067444 0,14951087 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,10067444 0,14939049 ! spinal cord development GO:0021510 11 11 0,000 0,10067444 0,1492703 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,10067444 0,14915031 ! smooth muscle contraction GO:0006939 11 11 0,000 0,10067444 0,14903051 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,10067444 0,1489109 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,10067444 0,14879149 ! digestive system process GO:0022600 11 11 0,000 0,10067444 0,14867226 ! mitotic spindle organization GO:0007052 11 11 0,000 0,10067444 0,14855323 ! fucose metabolic process GO:0006004 11 11 0,000 0,10067444 0,14843439 ! membrane budding GO:0006900 11 11 0,000 0,10067444 0,14831574 ! monoamine transport GO:0015844 11 11 0,000 0,10067444 0,14819727 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,10067444 0,148079 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,10067444 0,14796091 ! body fluid secretion GO:0007589 11 11 0,000 0,10067444 0,14784302 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,10067444 0,14772531 ! intermediate filament-based process GO:0045103 11 11 0,000 0,10067444 0,14760779 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,10067444 0,14749045 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,10067444 0,1473733 ! membrane depolarization GO:0051899 11 11 0,000 0,10067444 0,14725634 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,10067444 0,14713956 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,10067444 0,14702297 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,10067444 0,14690656 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,10067444 0,14679034 ! vitamin transport GO:0051180 11 11 0,000 0,10067444 0,1466743 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,10067444 0,14655844 ! steroid catabolic process GO:0006706 11 11 0,000 0,10067444 0,14644277 ! endocrine process GO:0050886 11 11 0,000 0,10067444 0,14632728 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,10067444 0,14621197 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,10067444 0,14609684 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,10067444 0,14598189 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,1093155 0,15838716 ! translational initiation GO:0006413 12 12 0,000 0,1093155 0,15826274 ! initiation of viral infection GO:0019059 12 12 0,000 0,1093155 0,15813852 ! iron ion transport GO:0006826 13 12 0,000 0,1093155 0,15801449 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,1093155 0,15789065 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,1093155 0,15776701 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,1093155 0,15764356 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,1093155 0,15752031 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,1093155 0,15739724 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,1093155 0,15727437 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,1093155 0,15715169 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,1093155 0,15702921 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,1093155 0,15690691 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,1093155 0,1567848 ! actomyosin structure organization GO:0031032 12 12 0,000 0,1093155 0,15666289 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,1093155 0,15654116 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,1093155 0,15641962 ! retinoid metabolic process GO:0001523 12 12 0,000 0,1093155 0,15629827 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,1093155 0,15617711 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,1093155 0,15605614 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,1093155 0,15593535 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,1093155 0,15581475 ! acute-phase response GO:0006953 12 12 0,000 0,1093155 0,15569434 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,1093155 0,15557411 ! vacuolar transport GO:0007034 12 12 0,000 0,1093155 0,15545407 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,1093155 0,15533421 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,1093155 0,15521454 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,1093155 0,15509505 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,1093155 0,15497575 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,1093155 0,15485663 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,1093155 0,15473769 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,1093155 0,15461893 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,1093155 0,15450036 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,1093155 0,15438197 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,1093155 0,15426376 ! pallium development GO:0021543 13 12 0,000 0,1093155 0,15414573 ! cell fate determination GO:0001709 12 12 0,000 0,1093155 0,15402788 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,1093155 0,15391022 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,1093155 0,15379273 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,1093155 0,15367542 ! detection of light stimulus GO:0009583 13 12 0,000 0,1093155 0,15355829 ! synaptogenesis GO:0007416 12 12 0,000 0,1093155 0,15344133 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,1093155 0,15332456 ! hormone transport GO:0009914 12 12 0,000 0,1093155 0,15320796 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,1093155 0,15309154 ! heme biosynthetic process GO:0006783 12 12 0,000 0,1093155 0,1529753 ! spermatid differentiation GO:0048515 13 12 0,000 0,1093155 0,15285924 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,1093155 0,15274334 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,1093155 0,15262763 ! neural tube closure GO:0001843 13 12 0,000 0,1093155 0,15251209 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,1093155 0,15239673 ! negative regulation of translation GO:0017148 12 12 0,000 0,1093155 0,15228154 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,1093155 0,15216652 ! carboxylic acid transport GO:0046942 59 59 1,000 0,10953756 0,15236055 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,10953756 0,15224565 ! protein localization in organelle GO:0033365 59 59 1,000 0,10953756 0,15213092 ! potassium ion transport GO:0006813 60 60 1,000 0,11264017 0,15632217 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,11576576 0,16053898 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,11576576 0,16041827 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,11787479 0,16321806 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,11787479 0,16309552 ! phenol metabolic process GO:0018958 13 13 0,000 0,11787479 0,16297317 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,11787479 0,162851 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,11787479 0,16272902 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,11787479 0,16260721 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,11787479 0,16248559 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,11787479 0,16236415 ! keratinization GO:0031424 13 13 0,000 0,11787479 0,16224289 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,11787479 0,16212182 ! patterning of blood vessels GO:0001569 13 13 0,000 0,11787479 0,16200092 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,11787479 0,16188021 ! regulation of innate immune response GO:0045088 13 13 0,000 0,11787479 0,16175967 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,11787479 0,16163931 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,11787479 0,16151913 ! autophagy GO:0006914 13 13 0,000 0,11787479 0,16139914 ! actin filament bundle formation GO:0051017 13 13 0,000 0,11787479 0,16127931 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,11787479 0,16115967 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,11787479 0,1610402 ! regulation of peptide secretion GO:0002791 13 13 0,000 0,11787479 0,16092092 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,11787479 0,1608018 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,11787479 0,16068287 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,11787479 0,16056411 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,11787479 0,16044552 ! vasodilation GO:0042311 14 13 0,000 0,11787479 0,16032711 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,11787479 0,16020888 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,11787479 0,16009082 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,11787479 0,15997293 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,11787479 0,15985521 ! immunoglobulin production GO:0002377 13 13 0,000 0,11787479 0,15973767 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,11787479 0,15962031 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,11787479 0,15950311 ! cell-cell junction organization GO:0045216 13 13 0,000 0,11787479 0,15938609 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,11787479 0,15926923 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,11787479 0,15915255 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,11787479 0,15903604 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,11787479 0,1589197 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,11787479 0,15880354 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,11787479 0,15868754 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,11787479 0,15857171 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,11787479 0,15845604 ! blastocyst development GO:0001824 13 13 0,000 0,11787479 0,15834055 ! telomere organization GO:0032200 13 13 0,000 0,11787479 0,15822523 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,11787479 0,15811007 ! regulation of amine transport GO:0051952 13 13 0,000 0,11787479 0,15799508 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,11787479 0,15788026 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,11891362 0,15915599 ! protein import GO:0017038 62 62 1,000 0,11891362 0,15904049 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,11891362 0,15892516 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,12527336 0,16730348 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,12527336 0,16718233 ! neuron fate commitment GO:0048663 14 14 0,000 0,12635306 0,16850122 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,12635306 0,16837938 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,12635306 0,16825772 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,12635306 0,16813623 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,12635306 0,16801492 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,12635306 0,16789379 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,12635306 0,16777283 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,12635306 0,16765204 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,12635306 0,16753143 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,12635306 0,16741099 ! vesicle docking GO:0048278 14 14 0,000 0,12635306 0,16729072 ! superoxide metabolic process GO:0006801 15 14 0,000 0,12635306 0,16717063 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,12635306 0,16705071 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,12635306 0,16693096 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,12635306 0,16681138 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,12635306 0,16669197 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,12635306 0,16657274 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 14 14 0,000 0,12635306 0,16645367 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,12635306 0,16633477 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,12635306 0,16621605 ! peptide transport GO:0015833 14 14 0,000 0,12635306 0,16609749 ! primary neural tube formation GO:0014020 15 14 0,000 0,12635306 0,1659791 ! peptide cross-linking GO:0018149 14 14 0,000 0,12635306 0,16586089 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,12635306 0,16574284 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,12635306 0,16562495 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,12635306 0,16550724 ! formation of primary germ layer GO:0001704 14 14 0,000 0,12635306 0,16538969 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,12635306 0,16527231 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,12635306 0,16515509 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,12635306 0,16503805 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,12635306 0,16492116 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,12635306 0,16480445 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,12635306 0,1646879 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,12635306 0,16457151 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,12635306 0,16445528 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,12635306 0,16433923 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,12848388 0,1669928 ! regulation of hormone levels GO:0010817 66 65 1,000 0,12848388 0,16687512 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,13171395 0,17094986 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,13171395 0,17082956 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,13475106 0,17464571 ! positive regulation of ossification GO:0045778 15 15 0,000 0,13475106 0,17452298 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,13475106 0,17440043 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,13475106 0,17427804 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,13475106 0,17415582 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,13475106 0,17403378 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,13475106 0,17391191 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,13475106 0,17379021 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,13475106 0,17366868 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,13475106 0,17354731 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,13475106 0,17342612 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,13475106 0,1733051 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,13475106 0,17318424 ! heme metabolic process GO:0042168 15 15 0,000 0,13475106 0,17306356 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,13475106 0,17294304 ! chromosome condensation GO:0030261 15 15 0,000 0,13475106 0,17282269 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,13475106 0,17270251 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,13475106 0,17258249 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,13475106 0,17246264 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,13475106 0,17234296 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,13475106 0,17222344 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,13475106 0,17210409 ! phospholipid transport GO:0015914 15 15 0,000 0,13475106 0,17198491 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,13475106 0,17186589 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,13475106 0,17174703 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,13475106 0,17162834 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,13475106 0,17150981 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,13475106 0,17139145 ! protein homooligomerization GO:0051260 15 15 0,000 0,13475106 0,17127325 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,13475106 0,17115521 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,1349629 0,17130621 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,13823009 0,17533246 ! regulation of translation GO:0006417 69 69 1,000 0,1415149 0,17937549 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,1415149 0,17925221 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,14306955 0,18109697 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,14306955 0,18097267 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,14306955 0,18084855 ! learning GO:0007612 16 16 0,000 0,14306955 0,18072459 ! circadian rhythm GO:0007623 16 16 0,000 0,14306955 0,18060081 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,14306955 0,18047719 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,14306955 0,18035375 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,14306955 0,18023047 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,14306955 0,18010736 ! vesicle targeting GO:0006903 17 16 0,000 0,14306955 0,17998442 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,14306955 0,17986165 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,14306955 0,17973905 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,14306955 0,17961661 ! cell fate specification GO:0001708 16 16 0,000 0,14306955 0,17949434 ! pentose metabolic process GO:0019321 16 16 0,000 0,14306955 0,17937223 ! fatty acid transport GO:0015908 16 16 0,000 0,14306955 0,17925029 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,14306955 0,17912852 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,14306955 0,17900691 ! cofactor catabolic process GO:0051187 16 16 0,000 0,14306955 0,17888547 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,14306955 0,17876419 ! polyol metabolic process GO:0019751 16 16 0,000 0,14306955 0,17864308 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,14306955 0,17852213 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,14306955 0,17840134 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,14306955 0,17828072 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,14306955 0,17816026 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,14306955 0,17803996 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,14306955 0,17791983 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,14481669 0,17997112 GO:0016053|organic acid biosynthetic process, ! calcium ion homeostasis GO:0055074 71 71 1,000 0,14813486 0,18397072 GO:0006874|cellular calcium ion homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,15130927 0,18778652 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,15130927 0,18766015 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,15130927 0,18753395 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,15130927 0,18740792 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,15130927 0,18728205 ! leukocyte adhesion GO:0007159 17 17 0,000 0,15130927 0,18715636 ! sensory perception of smell GO:0007608 17 17 0,000 0,15130927 0,18703084 ! glucose transport GO:0015758 17 17 0,000 0,15130927 0,18690548 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,15130927 0,18678029 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,15130927 0,18665527 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,15130927 0,18653042 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,15130927 0,18640573 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,15130927 0,18628121 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,15130927 0,18615686 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,15130927 0,18603267 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,15130927 0,18590865 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,15130927 0,1857848 ! adult locomotory behavior GO:0008344 17 17 0,000 0,15130927 0,1856611 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,15130927 0,18553758 ! liver development GO:0001889 17 17 0,000 0,15130927 0,18541421 ! gene silencing GO:0016458 17 17 0,000 0,15130927 0,18529102 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,15146879 0,1853632 ! sensory organ development GO:0007423 72 72 1,000 0,15146879 0,1852402 ! regulation of cytokine production GO:0001817 72 72 1,000 0,15146879 0,18511736 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,1581816 0,1931933 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,15947094 0,19463904 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,15947094 0,19451022 ! meiosis I GO:0007127 18 18 0,000 0,15947094 0,19438158 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,15947094 0,19425311 ! membrane docking GO:0022406 18 18 0,000 0,15947094 0,1941248 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,15947094 0,19399667 ! response to calcium ion GO:0051592 18 18 0,000 0,15947094 0,1938687 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,15947094 0,1937409 ! hexose transport GO:0008645 18 18 0,000 0,15947094 0,19361327 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,15947094 0,19348581 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,15947094 0,19335852 ! ceramide metabolic process GO:0006672 18 18 0,000 0,15947094 0,19323139 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,15947094 0,19310443 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,15947094 0,19297764 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,15947094 0,19285102 ! BMP signaling pathway GO:0030509 18 18 0,000 0,15947094 0,19272456 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,15947094 0,19259826 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,15947094 0,19247213 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,15947094 0,19234617 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,16155931 0,19473761 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,16155931 0,19461033 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,16755531 0,20170113 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,16755531 0,20156947 GO:0006956|complement activation, ! feeding behavior GO:0007631 19 19 0,000 0,16755531 0,20143799 ! peroxisome organization GO:0007031 19 19 0,000 0,16755531 0,20130667 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,16755531 0,20117553 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,16755531 0,20104455 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,16755531 0,20091375 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,16755531 0,20078312 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,16755531 0,20065265 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,16755531 0,20052236 ! eye morphogenesis GO:0048592 19 19 0,000 0,16755531 0,20039224 ! vesicle localization GO:0051648 20 19 0,000 0,16755531 0,20026228 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,16835452 0,20108709 ! metal ion homeostasis GO:0055065 78 78 1,000 0,17177092 0,20503484 ! nuclear transport GO:0051169 79 79 1,000 0,17519912 0,20899157 GO:0006913|nucleocytoplasmic transport, ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,17556308 0,20929028 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,17556308 0,20915499 ! neural tube development GO:0021915 21 20 0,000 0,17556308 0,20901987 ! phagocytosis GO:0006909 21 20 0,000 0,17556308 0,20888494 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,17556308 0,20875017 ! protein targeting to membrane GO:0006612 22 20 0,000 0,17556308 0,20861558 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,17556308 0,20848116 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,17556308 0,20834692 ! lipid oxidation GO:0034440 20 20 0,000 0,17556308 0,20821285 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,17556308 0,20807895 ! RNA modification GO:0009451 20 20 0,000 0,17556308 0,20794522 ! single fertilization GO:0007338 21 20 0,000 0,17556308 0,20781167 ! regulation of B cell activation GO:0050864 20 20 0,000 0,17556308 0,20767828 ! MAPKKK cascade GO:0000165 82 81 1,000 0,18208884 0,21525961 ! lipid catabolic process GO:0016042 82 81 1,000 0,18208884 0,21512162 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,18349499 0,21664398 ! mRNA catabolic process GO:0006402 21 21 0,000 0,18349499 0,21650529 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,18349499 0,21636677 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,18349499 0,21622843 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,18349499 0,21609026 ! Notch signaling pathway GO:0007219 22 21 0,000 0,18349499 0,21595227 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,18349499 0,21581446 ! ear morphogenesis GO:0042471 21 21 0,000 0,18349499 0,21567682 ! organic anion transport GO:0015711 21 21 0,000 0,18349499 0,21553936 ! cholesterol transport GO:0030301 21 21 0,000 0,18349499 0,21540207 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,18349499 0,21526496 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,18349499 0,21512803 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,18349499 0,21499126 ! regulation of proteolysis GO:0030162 21 21 0,000 0,18349499 0,21485467 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,18349499 0,21471826 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,18349499 0,21458202 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,18901954 0,22090235 ! RNA export from nucleus GO:0006405 22 22 0,000 0,19135172 0,2234862 ! sister chromatid segregation GO:0000819 22 22 0,000 0,19135172 0,22334466 ! regulation of ion transport GO:0043269 22 22 0,000 0,19135172 0,2232033 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,19135172 0,22306212 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,19135172 0,22292112 ! cell chemotaxis GO:0060326 23 22 0,000 0,19135172 0,2227803 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,19135172 0,22263966 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,19135172 0,22249919 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,19135172 0,2223589 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,19135172 0,22221879 ! detection of external stimulus GO:0009581 23 22 0,000 0,19135172 0,22207885 ! neuron migration GO:0001764 22 22 0,000 0,19135172 0,22193909 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,19135172 0,22179951 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,19135172 0,2216601 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,19135172 0,22152086 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,19135172 0,22138181 ! aerobic respiration GO:0009060 22 22 0,000 0,19135172 0,22124292 ! cytokine production GO:0001816 22 22 0,000 0,19135172 0,22110421 ! cytokinesis GO:0000910 23 22 0,000 0,19135172 0,22096567 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,19135172 0,22082731 ! viral infectious cycle GO:0019058 23 23 0,000 0,19913399 0,22966454 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,19913399 0,22952091 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,19913399 0,22937746 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,19913399 0,22923419 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,19913399 0,2290911 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,19913399 0,22894818 ! endocrine system development GO:0035270 23 23 0,000 0,19913399 0,22880545 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,19913399 0,22866289 ! lipid homeostasis GO:0055088 23 23 0,000 0,19913399 0,22852051 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,19913399 0,2283783 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,19913399 0,22823628 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,19948374 0,22849505 GO:0006644|phospholipid metabolic process, ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,20649973 0,23638447 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,20684248 0,23662985 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,20684248 0,23648306 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,20684248 0,23633645 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,20684248 0,23619002 ! fertilization GO:0009566 25 24 0,000 0,20684248 0,23604377 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,20684248 0,23589771 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,20684248 0,23575182 ! chemotaxis GO:0006935 90 89 1,000 0,21001829 0,23922355 GO:0042330|taxis, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,21447789 0,24415242 ! negative regulation of secretion GO:0051048 26 25 0,000 0,21447789 0,2440017 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,21447789 0,24385118 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,21447789 0,24370084 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,21447789 0,24355068 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,21447789 0,24340071 ! excretion GO:0007588 25 25 0,000 0,21447789 0,24325093 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,21447789 0,24310133 ! gastrulation GO:0007369 25 25 0,000 0,21447789 0,24295191 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,21447789 0,24280268 ! regulation of endocytosis GO:0030100 25 25 0,000 0,21447789 0,24265363 ! DNA replication GO:0006260 91 91 1,000 0,21707431 0,24544047 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,22061091 0,24928627 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,22061091 0,24913352 ! positive regulation of defense response GO:0031349 26 26 0,000 0,22204091 0,25059485 ! glycolysis GO:0006096 26 26 0,000 0,22204091 0,25044149 ! cellular defense response GO:0006968 26 26 0,000 0,22204091 0,25028831 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,22204091 0,25013533 ! regulation of protein secretion GO:0050708 26 26 0,000 0,22204091 0,24998253 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,22204091 0,24982991 GO:0035150|regulation of tube size, ! response to insulin stimulus GO:0032868 28 26 0,000 0,22204091 0,24967748 ! cofactor metabolic process GO:0051186 95 94 1,000 0,22769913 0,25588384 ! chloride transport GO:0006821 27 27 0,000 0,2295322 0,25778662 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,2295322 0,25762962 ! learning or memory GO:0007611 28 27 0,000 0,2295322 0,25747282 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,2295322 0,25731621 ! inner ear development GO:0048839 27 27 0,000 0,2295322 0,25715978 ! defense response to bacterium GO:0042742 27 27 0,000 0,2295322 0,25700355 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,2295322 0,25684751 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,23695243 0,26498989 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,23695243 0,26482919 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,23695243 0,26466869 ! carbohydrate transport GO:0008643 28 28 0,000 0,23695243 0,26450838 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,23695243 0,26434827 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,23695243 0,26418835 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,23695243 0,26402862 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,23695243 0,26386908 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,24192434 0,26924309 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,24430228 0,27172547 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,24430228 0,27156158 ! viral reproductive process GO:0022415 29 29 0,000 0,24430228 0,27139789 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,24430228 0,2712344 ! leukocyte migration GO:0050900 30 29 0,000 0,24430228 0,2710711 ! antigen processing and presentation GO:0019882 29 29 0,000 0,24430228 0,270908 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,24430228 0,2707451 ! tRNA processing GO:0008033 29 29 0,000 0,24430228 0,27058239 ! adult behavior GO:0030534 30 29 0,000 0,24430228 0,27041988 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,24430228 0,27025756 ! transition metal ion transport GO:0000041 31 30 0,000 0,25158239 0,27814418 ! RNA catabolic process GO:0006401 30 30 0,000 0,25158239 0,27797743 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,25158239 0,27781087 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,25158239 0,27764452 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,25158239 0,27747836 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,25158239 0,27731241 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,25158239 0,27714665 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,25158239 0,27698109 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,25158239 0,27681573 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,25158239 0,27665057 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,25158239 0,2764856 ! establishment of organelle localization GO:0051656 31 30 0,000 0,25158239 0,27632083 ! regulation of translational initiation GO:0006446 31 31 0,000 0,25879342 0,28407164 ! membrane fusion GO:0006944 31 31 0,000 0,25879342 0,28390255 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,25879342 0,28373366 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,25879342 0,28356497 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,25879342 0,28339648 ! ion transmembrane transport GO:0034220 31 31 0,000 0,25879342 0,28322819 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,25879342 0,28306011 ! digestion GO:0007586 31 31 0,000 0,25879342 0,28289222 ! regulation of heart contraction GO:0008016 31 31 0,000 0,25879342 0,28272453 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,25879342 0,28255704 ! camera-type eye development GO:0043010 31 31 0,000 0,25879342 0,28238974 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,25879342 0,28222265 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,25879342 0,28205575 ! cell redox homeostasis GO:0045454 32 32 0,000 0,26593602 0,28966908 ! glucose catabolic process GO:0006007 32 32 0,000 0,26593602 0,28949798 ! lipid modification GO:0030258 32 32 0,000 0,26593602 0,28932708 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,26593602 0,28915639 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,26593602 0,2889859 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,26593602 0,2888156 ! nuclear export GO:0051168 32 32 0,000 0,26593602 0,28864551 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,26593602 0,28847562 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,26593602 0,28830593 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,27301082 0,29580184 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,27301082 0,29562805 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,27301082 0,29545445 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,27301082 0,29528106 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,27301082 0,29510788 ! regulation of actin filament length GO:0030832 34 34 0,000 0,28001845 0,30250528 ! muscle cell differentiation GO:0042692 35 34 0,000 0,28001845 0,30232807 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,28001845 0,30215106 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,28001845 0,30197426 ! viral reproduction GO:0016032 34 34 0,000 0,28001845 0,30179767 ! detection of stimulus GO:0051606 36 34 0,000 0,28001845 0,30162128 ! acute inflammatory response GO:0002526 35 35 0,000 0,28695955 0,30891732 ! regulation of cellular component size GO:0032535 35 35 0,000 0,28695955 0,30873699 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,28695955 0,30855686 ! mesoderm development GO:0007498 35 35 0,000 0,28695955 0,30837694 ! inorganic anion transport GO:0015698 35 35 0,000 0,28695955 0,30819724 ! regulation of immune effector process GO:0002697 35 35 0,000 0,28695955 0,30801774 ! hydrogen transport GO:0006818 36 36 0,000 0,29383474 0,31521387 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,29383474 0,3150305 ! regulation of mitosis GO:0007088 37 36 0,000 0,29383474 0,31484734 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,29383474 0,3146644 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,29383474 0,31448167 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,29383474 0,31429915 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,29383474 0,31411684 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,29383474 0,31393474 ! regulation of lipase activity GO:0060191 36 36 0,000 0,29383474 0,31375286 ! activation of immune response GO:0002253 36 36 0,000 0,29383474 0,31357118 ! meiosis GO:0007126 37 37 0,000 0,30064464 0,32065282 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,30064464 0,32046736 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,30064464 0,32028212 ! eye development GO:0001654 37 37 0,000 0,30064464 0,32009709 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,30064464 0,31991228 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,30064464 0,31972768 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,30064464 0,31954329 ! positive regulation of secretion GO:0051047 39 38 0,000 0,30738984 0,3265242 ! neurotransmitter transport GO:0006836 40 38 0,000 0,30738984 0,32633611 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,30738984 0,32614823 ! exocytosis GO:0006887 40 38 0,000 0,30738984 0,32596058 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,30738984 0,32577314 ! chromosome segregation GO:0007059 38 38 0,000 0,30738984 0,32558591 ! hexose catabolic process GO:0019320 38 38 0,000 0,30738984 0,3253989 ! RNA elongation GO:0006354 38 38 0,000 0,30738984 0,3252121 ! regulation of neurological system process GO:0031644 38 38 0,000 0,30738984 0,32502552 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,30738984 0,32483915 ! response to unfolded protein GO:0006986 39 39 0,000 0,31407097 0,33170934 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,31407097 0,33151936 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,31407097 0,33132959 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,31407097 0,33114005 ! limb development GO:0060173 39 39 0,000 0,31407097 0,33095071 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,32068862 0,33773093 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,32068862 0,33753805 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,32068862 0,33734539 ! organelle localization GO:0051640 41 40 0,000 0,32068862 0,33715295 ! amine catabolic process GO:0009310 42 41 0,000 0,32724338 0,34384809 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,32724338 0,34365216 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,32724338 0,34345646 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,32724338 0,34326098 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,32724338 0,34306572 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,32724338 0,34287069 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,33373584 0,34947451 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,33373584 0,34927606 ! protein ubiquitination GO:0016567 43 42 0,000 0,33373584 0,34907784 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,33373584 0,34887983 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! alcohol catabolic process GO:0046164 43 43 0,000 0,34016658 0,3554008 ! mRNA transport GO:0051028 44 44 0,000 0,34653619 0,36185054 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,34653619 0,36164564 ! vitamin metabolic process GO:0006766 44 44 0,000 0,34653619 0,36144097 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,34653619 0,36123654 ! amine biosynthetic process GO:0009309 46 45 0,000 0,35284523 0,36760529 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,35284523 0,3673976 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,35284523 0,36719015 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,35284523 0,36698293 ! protein processing GO:0016485 45 45 0,000 0,35284523 0,36677595 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,35909427 0,3730613 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,35909427 0,37285113 ! regulation of blood pressure GO:0008217 48 47 0,000 0,36528388 0,3790643 ! calcium ion transport GO:0006816 48 48 0,000 0,37141461 0,38520941 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,37141461 0,38499276 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,37141461 0,38477635 ! divalent metal ion transport GO:0070838 49 49 0,000 0,37748701 0,39084751 ! response to bacterium GO:0009617 50 49 0,000 0,37748701 0,39062805 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,37748701 0,39040884 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,37748701 0,39018988 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,38350163 0,3961847 ! chromatin assembly GO:0031497 50 50 0,000 0,38350163 0,39596275 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,38350163 0,39574104 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,38350163 0,39551959 ! transcription initiation GO:0006352 50 50 0,000 0,38350163 0,39529838 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,38945901 0,40121462 ! positive regulation of immune response GO:0050778 51 51 0,000 0,38945901 0,40099047 ! rRNA metabolic process GO:0016072 51 51 0,000 0,38945901 0,40076658 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,38945901 0,40054294 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,38945901 0,40031955 ! protein maturation GO:0051604 51 51 0,000 0,38945901 0,4000964 ! RNA localization GO:0006403 52 52 0,000 0,39535968 0,40593197 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,39535968 0,40570595 ! sodium ion transport GO:0006814 53 53 0,000 0,40120418 0,4114743 ! tRNA metabolic process GO:0006399 53 53 0,000 0,40120418 0,41124544 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,40120418 0,41101685 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,40120418 0,4107885 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,40120418 0,41056042 ! nucleosome organization GO:0034728 55 55 0,000 0,41272677 0,42211734 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,41272677 0,42188322 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,4184059 0,42745126 ! ATP metabolic process GO:0046034 57 57 0,000 0,42403093 0,4329579 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,42403093 0,43271816 ! innate immune response GO:0045087 58 58 0,000 0,42960237 0,43816114 ! sterol metabolic process GO:0016125 59 59 0,000 0,43512073 0,44354398 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,4405865 0,44886729 ! cellular respiration GO:0045333 62 61 0,000 0,44600018 0,45413168 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,44600018 0,45388091 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,45136226 0,45908424 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,45136226 0,45883102 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,45136226 0,45857808 ! regulation of secretion GO:0051046 65 63 0,000 0,45667321 0,46371831 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,45667321 0,46346296 ! glucose metabolic process GO:0006006 63 63 0,000 0,45667321 0,46320789 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,45667321 0,4629531 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,45667321 0,46269859 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,46193353 0,46777115 ! anion transport GO:0006820 65 65 0,000 0,46714368 0,47278737 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,47230413 0,47774782 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,47230413 0,47748575 ! DNA packaging GO:0006323 66 66 0,000 0,47230413 0,47722397 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,47741537 0,48212412 ! muscle contraction GO:0006936 67 67 0,000 0,47741537 0,48186009 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,48247783 0,48670314 ! sensory perception of sound GO:0007605 71 69 0,000 0,48749199 0,4914922 GO:0050954|sensory perception of mechanical stimulus, ! translational elongation GO:0006414 71 71 0,000 0,49737721 0,50118436 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,49737721 0,50091049 ! ribosome biogenesis GO:0042254 71 71 0,000 0,49737721 0,50063692 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,49737721 0,50036364 ! secretion by cell GO:0032940 75 72 0,000 0,50224916 0,5049892 ! muscle system process GO:0003012 72 72 0,000 0,50224916 0,50471385 ! electron transport chain GO:0022900 75 74 0,000 0,51185395 0,51408546 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,52127616 0,52326359 ! regulation of immune response GO:0050776 78 78 0,000 0,5305192 0,53225198 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,53958643 0,54105429 ! ncRNA processing GO:0034470 83 83 0,000 0,55286483 0,55406736 ! hexose metabolic process GO:0019318 87 86 0,000 0,56576591 0,56668835 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,58239863 0,58303133 ! visual perception GO:0007601 93 92 0,000 0,59047809 0,59079865 GO:0050953|sensory perception of light stimulus, ! regulation of system process GO:0044057 98 98 0,000 0,61380401 0,61380401