pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6906-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cell migration GO:0030335 126 57 9,000 1,471E-11 3,54E-08 ! positive regulation of cell motion GO:0051272 146 64 9,000 4,93E-11 5,931E-08 ! negative regulation of phosphorylation GO:0042326 47 24 6,000 3,791E-10 3,04E-07 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 6,000 7,113E-10 4,279E-07 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of mitochondrial membrane permeability GO:0046902 14 5 3,000 1,535E-08 7,386E-06 ! induction of apoptosis by intracellular signals GO:0008629 93 45 6,000 4,348E-08 1,743E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 1,309E-07 4,499E-05 ! apoptotic mitochondrial changes GO:0008637 41 20 4,000 3,22E-07 9,683E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 3,778E-07 1,01E-04 ! inactivation of MAPK activity GO:0000188 39 21 4,000 4,2E-07 1,011E-04 ! positive regulation of locomotion GO:0040017 39 21 4,000 4,2E-07 9,186E-05 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 4,000 5,402E-07 1,083E-04 ! protein sumoylation GO:0016925 15 10 3,000 6,259E-07 1,158E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 7,244E-07 1,245E-04 ! negative regulation of kinase activity GO:0033673 131 68 6,000 8,024E-07 1,287E-04 ! regulation of behavior GO:0050795 43 24 4,000 8,613E-07 1,295E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 3,000 9,777E-07 1,384E-04 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,189E-06 1,589E-04 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 1,458E-06 1,846E-04 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 3,000 1,458E-06 1,754E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 4,000 1,606E-06 1,84E-04 ! regulation of mRNA stability GO:0043488 31 13 3,000 2,094E-06 2,29E-04 ! cellular response to extracellular stimulus GO:0031668 48 29 4,000 2,334E-06 2,442E-04 ! response to hypoxia GO:0001666 171 81 6,000 2,65E-06 2,657E-04 ! regulation of RNA stability GO:0043487 32 14 3,000 2,914E-06 2,804E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 2,914E-06 2,696E-04 ! response to oxygen levels GO:0070482 176 83 6,000 3,124E-06 2,784E-04 ! negative regulation of growth GO:0045926 155 84 6,000 3,387E-06 2,91E-04 ! negative regulation of MAP kinase activity GO:0043407 69 32 4,000 3,886E-06 3,224E-04 ! negative regulation of survival gene product expression GO:0008634 8 5 2,000 4,124E-06 3,307E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 4,124E-06 3,201E-04 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 3,000 6,806E-06 5,117E-04 ! regulation of homeostatic process GO:0032844 134 62 5,000 7,232E-06 5,273E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 6,000 7,706E-06 5,453E-04 ! regulation of protein stability GO:0031647 73 37 4,000 8,158E-06 5,608E-04 ! neural nucleus development GO:0048857 14 6 2,000 8,202E-06 5,482E-04 ! cell-substrate junction assembly GO:0007044 54 18 3,000 8,699E-06 5,657E-04 ! nucleus organization GO:0006997 67 38 4,000 9,337E-06 5,912E-04 ! interphase GO:0051325 213 98 6,000 9,465E-06 5,839E-04 ! cell cycle arrest GO:0007050 213 100 6,000 1,081E-05 6,505E-04 ! negative regulation of cell growth GO:0030308 132 67 5,000 1,138E-05 6,678E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 1,138E-05 6,519E-04 ! negative regulation of cell size GO:0045792 134 69 5,000 1,35E-05 7,554E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 1,361E-05 7,444E-04 ! prostate gland development GO:0030850 13 7 2,000 1,427E-05 7,632E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 1,427E-05 7,466E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 1,427E-05 7,307E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 1,427E-05 7,155E-04 ! cell structure disassembly during apoptosis GO:0006921 30 21 3,000 1,672E-05 8,208E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 1,737E-05 8,358E-04 ! apoptotic nuclear changes GO:0030262 32 22 3,000 2,031E-05 9,582E-04 ! positive regulation of intracellular transport GO:0032388 37 22 3,000 2,031E-05 9,398E-04 ! cell-matrix adhesion GO:0007160 163 75 5,000 2,184E-05 9,916E-04 ! ER overload response GO:0006983 12 8 2,000 2,271E-05 1,012E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 2,271E-05 9,935E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 2,271E-05 9,758E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,271E-05 9,587E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 2,271E-05 9,421E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 2,428E-05 9,903E-04 ! pigmentation GO:0043473 100 46 4,000 2,428E-05 9,738E-04 ! positive regulation of fibroblast proliferation GO:0048146 43 24 3,000 2,916E-05 1,15E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 3,000 2,916E-05 1,132E-03 ! regulation of glycolysis GO:0006110 21 9 2,000 3,388E-05 1,294E-03 ! middle ear morphogenesis GO:0042474 14 9 2,000 3,388E-05 1,274E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 3,388E-05 1,254E-03 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 2,000 3,388E-05 1,235E-03 ! cell-substrate adhesion GO:0031589 171 81 5,000 3,391E-05 1,218E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 3,451E-05 1,221E-03 ! cellular response to nutrient levels GO:0031669 41 25 3,000 3,451E-05 1,203E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 4,055E-05 1,394E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 4,055E-05 1,374E-03 ! cartilage development GO:0051216 90 52 4,000 4,439E-05 1,483E-03 ! mitochondrial membrane organization GO:0007006 57 27 3,000 4,732E-05 1,56E-03 ! response to toxin GO:0009636 47 27 3,000 4,732E-05 1,538E-03 ! mitochondrion organization GO:0007005 148 86 5,000 4,762E-05 1,528E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 4,813E-05 1,524E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 4,813E-05 1,504E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 4,813E-05 1,485E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 4,813E-05 1,466E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 4,813E-05 1,448E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 5,488E-05 1,63E-03 ! regulation of DNA replication GO:0006275 101 56 4,000 6,367E-05 1,868E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 6,581E-05 1,908E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 6,581E-05 1,885E-03 GO:0010829|negative regulation of glucose transport, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 6,937E-05 1,964E-03 ! cell junction assembly GO:0034329 78 30 3,000 7,259E-05 2,031E-03 ! skeletal system morphogenesis GO:0048705 105 59 4,000 8,194E-05 2,266E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 8,726E-05 2,386E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 8,726E-05 2,359E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 8,726E-05 2,333E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 8,726E-05 2,307E-03 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 9,347E-05 2,445E-03 ! actin filament organization GO:0007015 148 66 4,000 1,402E-04 3,627E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 1,428E-04 3,655E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 1,428E-04 3,616E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 1,428E-04 3,579E-03 GO:0060675|ureteric bud morphogenesis, ! response to gamma radiation GO:0010332 28 14 2,000 1,428E-04 3,542E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 1,428E-04 3,506E-03 ! lung development GO:0030324 144 67 4,000 1,506E-04 3,659E-03 ! cell junction organization GO:0034330 86 36 3,000 1,506E-04 3,624E-03 ! negative regulation of cell activation GO:0050866 65 36 3,000 1,506E-04 3,588E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 1,731E-04 4,083E-03 ! urogenital system development GO:0001655 137 69 4,000 1,731E-04 4,043E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 1,775E-04 4,106E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,775E-04 4,067E-03 ! G1/S transition checkpoint GO:0031575 40 15 2,000 1,775E-04 4,029E-03 ! respiratory tube development GO:0030323 150 70 4,000 1,853E-04 4,166E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 1,866E-04 4,156E-03 GO:0042593|glucose homeostasis, ! mitotic cell cycle checkpoint GO:0007093 76 38 3,000 1,866E-04 4,118E-03 ! respiratory system development GO:0060541 153 72 4,000 2,116E-04 4,629E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 2,172E-04 4,709E-03 ! axon cargo transport GO:0008088 43 16 2,000 2,172E-04 4,667E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 2,172E-04 4,626E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 2,172E-04 4,585E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 2,172E-04 4,545E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 2,000 2,172E-04 4,506E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 2,623E-04 5,395E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 2,623E-04 5,349E-03 ! negative regulation of blood coagulation GO:0030195 24 17 2,000 2,623E-04 5,304E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 2,623E-04 5,26E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 2,763E-04 5,494E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 3,131E-04 6,174E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 3,131E-04 6,124E-03 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 3,614E-04 7,013E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 3,697E-04 7,116E-03 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 3,697E-04 7,06E-03 ! cellular pigmentation GO:0033059 36 19 2,000 3,697E-04 7,004E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 3,697E-04 6,95E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 3,935E-04 7,34E-03 ! positive regulation of protein transport GO:0051222 72 46 3,000 3,935E-04 7,283E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 4,326E-04 7,945E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 2,000 4,326E-04 7,884E-03 ! cellular response to starvation GO:0009267 33 20 2,000 4,326E-04 7,825E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 4,326E-04 7,767E-03 ! regulation of glucose import GO:0046324 29 20 2,000 4,326E-04 7,709E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 4,326E-04 7,653E-03 ! negative regulation of coagulation GO:0050819 29 20 2,000 4,326E-04 7,597E-03 ! mitochondrial transport GO:0006839 82 48 3,000 4,638E-04 8,086E-03 ! cellular component disassembly GO:0022411 86 48 3,000 4,638E-04 8,027E-03 ! activation of caspase activity GO:0006919 84 48 3,000 4,638E-04 7,97E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 4,638E-04 7,914E-03 ! tube morphogenesis GO:0035239 176 86 4,000 4,839E-04 8,198E-03 ! cell aging GO:0007569 44 21 2,000 5,019E-04 8,444E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 5,019E-04 8,385E-03 ! gland development GO:0048732 206 88 4,000 5,377E-04 8,923E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 5,523E-04 9,102E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,523E-04 9,04E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 5,523E-04 8,979E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 5,523E-04 8,919E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 5,523E-04 8,86E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 5,523E-04 8,801E-03 ! microvillus organization GO:0032528 7 5 1,000 5,523E-04 8,743E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 5,523E-04 8,686E-03 ! mRNA transcription GO:0009299 9 5 1,000 5,523E-04 8,629E-03 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 5,523E-04 8,574E-03 GO:0051489|regulation of filopodium assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 5,523E-04 8,519E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 5,523E-04 8,465E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 5,523E-04 8,411E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 5,523E-04 8,358E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 5,523E-04 8,306E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 5,523E-04 8,254E-03 ! B cell homeostasis GO:0001782 13 5 1,000 5,523E-04 8,203E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 5,523E-04 8,153E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 5,523E-04 8,103E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 5,523E-04 8,054E-03 ! stem cell division GO:0017145 11 5 1,000 5,523E-04 8,006E-03 GO:0048103|somatic stem cell division, ! microtubule-based transport GO:0010970 54 22 2,000 5,779E-04 8,326E-03 ! ureteric bud development GO:0001657 43 22 2,000 5,779E-04 8,276E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 5,852E-04 8,332E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 3,000 5,852E-04 8,283E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 6,303E-04 8,869E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 6,303E-04 8,817E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 6,609E-04 9,192E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 6,609E-04 9,139E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 6,609E-04 9,087E-03 ! response to UV GO:0009411 104 53 3,000 6,778E-04 9,266E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 6,921E-04 9,408E-03 ! negative regulation of multicellular organismal process GO:0051241 166 93 4,000 6,921E-04 9,355E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 7,512E-04 0,01009681 ! positive regulation of caspase activity GO:0043280 95 55 3,000 7,802E-04 0,01042928 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 3,000 7,802E-04 0,01037166 ! negative regulation of cell motion GO:0051271 134 55 3,000 7,802E-04 0,01031467 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 8,244E-04 0,01083902 ! embryonic hemopoiesis GO:0035162 14 6 1,000 8,244E-04 0,01078011 ! toxin metabolic process GO:0009404 11 6 1,000 8,244E-04 0,01072184 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 8,244E-04 0,01066419 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! neuron apoptosis GO:0051402 9 6 1,000 8,244E-04 0,01060716 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 8,244E-04 0,01055074 ! negative regulation of platelet activation GO:0010544 9 6 1,000 8,244E-04 0,01049492 GO:0010543|regulation of platelet activation, ! purine base biosynthetic process GO:0009113 17 6 1,000 8,244E-04 0,01043968 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 8,244E-04 0,01038503 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 8,244E-04 0,01033094 ! triglyceride catabolic process GO:0019433 10 6 1,000 8,244E-04 0,01027741 ! negative regulation of B cell activation GO:0050869 13 6 1,000 8,244E-04 0,01022443 ! regulation of protein localization GO:0032880 176 97 4,000 8,377E-04 0,01033602 ! response to starvation GO:0042594 42 25 2,000 8,489E-04 0,01042072 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 8,489E-04 0,01036782 ! regulation of blood coagulation GO:0030193 40 25 2,000 8,489E-04 0,01031546 ! regulation of intracellular transport GO:0032386 101 57 3,000 8,932E-04 0,01079891 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 9,543E-04 0,01148072 ! cellular response to oxidative stress GO:0034599 39 26 2,000 9,543E-04 0,01142361 ! DNA catabolic process GO:0006308 86 59 3,000 1,017E-03 0,0121152 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,068E-03 0,01265484 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 1,068E-03 0,0125928 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 1,083E-03 0,01271612 ! regulation of helicase activity GO:0051095 15 7 1,000 1,148E-03 0,01341368 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,148E-03 0,01334888 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,148E-03 0,0132847 ! mRNA stabilization GO:0048255 18 7 1,000 1,148E-03 0,01322114 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 1,148E-03 0,01315818 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,148E-03 0,01309582 ! glycerol ether catabolic process GO:0044269 12 7 1,000 1,148E-03 0,01303405 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 1,148E-03 0,01297286 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,148E-03 0,01291224 ! fibrinolysis GO:0042730 10 7 1,000 1,148E-03 0,01285218 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 1,148E-03 0,01279268 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,148E-03 0,01273373 ! oxygen homeostasis GO:0032364 12 7 1,000 1,148E-03 0,01267531 ! response to tumor cell GO:0002347 13 7 1,000 1,148E-03 0,01261744 ! peptidyl-threonine modification GO:0018210 25 7 1,000 1,148E-03 0,01256008 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 1,148E-03 0,01250325 ! negative regulation of protein modification process GO:0031400 60 28 2,000 1,189E-03 0,01288901 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,189E-03 0,01283121 ! ear development GO:0043583 103 62 3,000 1,225E-03 0,01315855 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 1,319E-03 0,01410643 ! regulation of coagulation GO:0050818 46 29 2,000 1,319E-03 0,01404401 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 1,458E-03 0,01545022 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,458E-03 0,01538246 ! regulation of B cell activation GO:0050864 50 30 2,000 1,458E-03 0,01531528 ! neutral lipid catabolic process GO:0046461 13 8 1,000 1,524E-03 0,01593946 ! succinate metabolic process GO:0006105 14 8 1,000 1,524E-03 0,01587046 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,524E-03 0,01580205 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,524E-03 0,01573423 ! glycerolipid catabolic process GO:0046503 13 8 1,000 1,524E-03 0,01566699 ! hemoglobin metabolic process GO:0020027 13 8 1,000 1,524E-03 0,01560033 ! pigment granule organization GO:0048753 16 8 1,000 1,524E-03 0,01553422 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,524E-03 0,01546868 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,524E-03 0,01540368 ! melanin metabolic process GO:0006582 15 8 1,000 1,524E-03 0,01533923 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,524E-03 0,01527532 ! synaptic transmission, glutamatergic GO:0035249 17 8 1,000 1,524E-03 0,01521194 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,524E-03 0,01514908 ! response to UV-B GO:0010224 16 8 1,000 1,524E-03 0,01508673 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 1,000 1,524E-03 0,0150249 ! iron ion homeostasis GO:0055072 54 31 2,000 1,605E-03 0,01576168 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 1,605E-03 0,01569761 GO:0043433|negative regulation of transcription factor activity, ! spindle organization GO:0007051 46 32 2,000 1,761E-03 0,0171565 ! metanephros development GO:0001656 74 32 2,000 1,761E-03 0,01708732 ! response to ionizing radiation GO:0010212 65 32 2,000 1,761E-03 0,0170187 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,761E-03 0,01695063 ! hindbrain development GO:0030902 61 32 2,000 1,761E-03 0,01688309 ! DNA damage checkpoint GO:0000077 71 33 2,000 1,927E-03 0,01839602 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 1,927E-03 0,01832331 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,927E-03 0,01825117 GO:0060326|cell chemotaxis, ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,949E-03 0,01839309 ! microtubule bundle formation GO:0001578 21 9 1,000 1,949E-03 0,01832124 ! T cell selection GO:0045058 23 9 1,000 1,949E-03 0,01824995 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,949E-03 0,01817922 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 18 9 1,000 1,949E-03 0,01810903 ! behavioral fear response GO:0001662 22 9 1,000 1,949E-03 0,01803938 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,949E-03 0,01797026 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,949E-03 0,01790167 ! gas homeostasis GO:0033483 16 9 1,000 1,949E-03 0,0178336 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,949E-03 0,01776605 ! purine base metabolic process GO:0006144 21 9 1,000 1,949E-03 0,01769901 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,949E-03 0,01763247 ! reproductive structure development GO:0048608 113 71 3,000 2,025E-03 0,01824505 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 2,102E-03 0,01886748 ! regulation of caspase activity GO:0043281 122 72 3,000 2,131E-03 0,01906332 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 2,131E-03 0,01899272 ! regulation of muscle development GO:0048634 70 35 2,000 2,286E-03 0,02029576 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 2,286E-03 0,02022114 ! regulation of transcription factor activity GO:0051090 126 74 3,000 2,356E-03 0,02076536 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 3,000 2,356E-03 0,02068958 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 2,425E-03 0,02121399 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,425E-03 0,02113713 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,425E-03 0,02106082 ! lung alveolus development GO:0048286 26 10 1,000 2,425E-03 0,02098506 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,425E-03 0,02090985 ! B cell proliferation GO:0042100 18 10 1,000 2,425E-03 0,02083517 ! nucleobase biosynthetic process GO:0046112 24 10 1,000 2,425E-03 0,02076102 ! epithelial cell development GO:0002064 20 10 1,000 2,425E-03 0,0206874 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 2,425E-03 0,0206143 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,425E-03 0,02054171 ! regulation of bone resorption GO:0045124 25 10 1,000 2,425E-03 0,02046964 ! alpha-beta T cell activation GO:0046631 23 10 1,000 2,425E-03 0,02039807 ! apical protein localization GO:0045176 15 10 1,000 2,425E-03 0,02032699 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,425E-03 0,02025641 ! oocyte development GO:0048599 17 10 1,000 2,425E-03 0,02018632 ! response to nicotine GO:0035094 20 10 1,000 2,425E-03 0,02011671 ! DNA integrity checkpoint GO:0031570 75 36 2,000 2,48E-03 0,0205059 ! regulation of catabolic process GO:0009894 161 76 3,000 2,597E-03 0,02139684 ! tissue remodeling GO:0048771 76 37 2,000 2,684E-03 0,02204127 ! negative regulation of DNA binding GO:0043392 68 37 2,000 2,684E-03 0,0219663 ! pigment metabolic process GO:0042440 80 37 2,000 2,684E-03 0,02189184 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,898E-03 0,02355801 ! negative regulation of muscle development GO:0048635 20 11 1,000 2,949E-03 0,02388912 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,949E-03 0,02380896 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,949E-03 0,02372933 ! blood vessel remodeling GO:0001974 29 11 1,000 2,949E-03 0,02365023 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,949E-03 0,02357166 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,949E-03 0,02349361 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,949E-03 0,02341607 ! substrate-bound cell migration GO:0006929 13 11 1,000 2,949E-03 0,02333905 ! negative regulation of ossification GO:0030279 26 11 1,000 2,949E-03 0,02326252 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 2,949E-03 0,0231865 ! nitric oxide metabolic process GO:0046209 15 11 1,000 2,949E-03 0,02311098 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 2,949E-03 0,02303594 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,949E-03 0,02296139 ! oocyte differentiation GO:0009994 18 11 1,000 2,949E-03 0,02288732 ! thymus development GO:0048538 27 11 1,000 2,949E-03 0,02281373 ! regulation of peptidase activity GO:0052547 134 79 3,000 2,989E-03 0,02304617 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 2,989E-03 0,02297254 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 2,989E-03 0,02289937 ! ear morphogenesis GO:0042471 60 39 2,000 3,123E-03 0,02385026 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 3,123E-03 0,02377479 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 3,271E-03 0,02482661 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of binding GO:0051100 72 40 2,000 3,357E-03 0,02540078 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 3,357E-03 0,02532115 ! mesenchymal cell development GO:0014031 87 40 2,000 3,357E-03 0,02524203 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! response to drug GO:0042493 143 82 3,000 3,419E-03 0,02562525 ! response to nutrient GO:0007584 125 82 3,000 3,419E-03 0,02554567 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,521E-03 0,02622939 ! cartilage condensation GO:0001502 20 12 1,000 3,521E-03 0,02614844 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 3,521E-03 0,02606798 ! regulation of cell projection assembly GO:0060491 30 12 1,000 3,521E-03 0,02598802 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 3,521E-03 0,02590854 ! asymmetric protein localization GO:0008105 20 12 1,000 3,521E-03 0,02582955 ! fear response GO:0042596 26 12 1,000 3,521E-03 0,02575104 ! cranial nerve development GO:0021545 20 12 1,000 3,521E-03 0,02567301 ! histone acetylation GO:0016573 26 12 1,000 3,521E-03 0,02559545 ! mRNA polyadenylation GO:0006378 23 12 1,000 3,521E-03 0,02551835 ! autonomic nervous system development GO:0048483 24 12 1,000 3,521E-03 0,02544172 ! gland morphogenesis GO:0022612 29 12 1,000 3,521E-03 0,02536555 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 3,521E-03 0,02528983 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,521E-03 0,02521456 ! T cell homeostasis GO:0043029 25 12 1,000 3,521E-03 0,02513974 ! spleen development GO:0048536 22 12 1,000 3,521E-03 0,02506536 ! digestive tract morphogenesis GO:0048546 26 12 1,000 3,521E-03 0,02499142 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of T cell proliferation GO:0042129 71 41 2,000 3,602E-03 0,02549228 ! T cell differentiation GO:0030217 81 41 2,000 3,602E-03 0,02541752 ! regulation of T cell differentiation GO:0045580 70 41 2,000 3,602E-03 0,0253432 ! negative regulation of transport GO:0051051 153 84 3,000 3,728E-03 0,02615025 ! regulation of ligase activity GO:0051340 142 84 3,000 3,728E-03 0,02607423 ! response to reactive oxygen species GO:0000302 67 42 2,000 3,858E-03 0,02690711 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 3,858E-03 0,02682935 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 3,858E-03 0,02675203 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 4,125E-03 0,02851874 ! regulation of chemokine production GO:0032642 18 13 1,000 4,141E-03 0,02854763 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 4,141E-03 0,02846606 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 4,141E-03 0,02838496 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 4,141E-03 0,02830433 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! response to X-ray GO:0010165 25 13 1,000 4,141E-03 0,02822414 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,141E-03 0,02814441 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 4,141E-03 0,02806513 ! regulation of cellular pH GO:0030641 22 13 1,000 4,141E-03 0,0279863 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,141E-03 0,02790791 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 4,141E-03 0,02782995 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 4,141E-03 0,02775243 ! mRNA 3'-end processing GO:0031124 24 13 1,000 4,141E-03 0,02767534 ! embryonic placenta development GO:0001892 23 13 1,000 4,141E-03 0,02759868 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 4,141E-03 0,02752244 ! regulation of protein transport GO:0051223 154 87 3,000 4,226E-03 0,02801318 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 3,000 4,402E-03 0,02909727 ! regulation of DNA binding GO:0051101 155 88 3,000 4,402E-03 0,02901755 ! male sex differentiation GO:0046661 76 44 2,000 4,402E-03 0,02894097 ! B cell differentiation GO:0030183 107 44 2,000 4,402E-03 0,02886211 ! regulation of cell adhesion GO:0030155 212 89 3,000 4,583E-03 0,02996116 ! leukocyte migration GO:0050900 68 45 2,000 4,691E-03 0,03058776 ! cell growth GO:0016049 84 45 2,000 4,691E-03 0,03050509 ! sex differentiation GO:0007548 145 90 3,000 4,768E-03 0,03092139 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,807E-03 0,03109243 ! hair follicle morphogenesis GO:0031069 26 14 1,000 4,807E-03 0,03100908 ! RNA polyadenylation GO:0043631 30 14 1,000 4,807E-03 0,03092616 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 4,807E-03 0,03084369 ! male genitalia development GO:0030539 24 14 1,000 4,807E-03 0,03076166 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,991E-03 0,03185221 ! negative regulation of cell migration GO:0030336 115 46 2,000 4,991E-03 0,03176795 ! positive regulation of defense response GO:0031349 76 47 2,000 5,302E-03 0,03365932 ! regulation of membrane potential GO:0042391 164 93 3,000 5,354E-03 0,03390163 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,52E-03 0,03485598 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 5,52E-03 0,03476473 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 5,52E-03 0,03467396 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 5,52E-03 0,03458367 ! muscle maintenance GO:0046716 26 15 1,000 5,52E-03 0,03449384 ! lymphocyte homeostasis GO:0002260 30 15 1,000 5,52E-03 0,03440448 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 5,52E-03 0,03431558 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 5,52E-03 0,03422713 ! regulation of inflammatory response GO:0050727 75 48 2,000 5,625E-03 0,03478909 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 5,625E-03 0,03469988 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 5,959E-03 0,03666691 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 6,277E-03 0,03852709 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 6,277E-03 0,03842905 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 6,277E-03 0,03833152 GO:0031114|regulation of microtubule depolymerization, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 6,277E-03 0,03823448 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,277E-03 0,03813792 ! negative regulation of immune system process GO:0002683 95 50 2,000 6,304E-03 0,03820796 ! embryonic skeletal system development GO:0048706 85 51 2,000 6,662E-03 0,04027284 ! regulation of cell shape GO:0008360 125 51 2,000 6,662E-03 0,0401719 ! regulation of muscle contraction GO:0006937 81 52 2,000 7,031E-03 0,04229271 ! positive regulation of growth GO:0045927 90 52 2,000 7,031E-03 0,04218724 ! metencephalon development GO:0022037 30 17 1,000 7,079E-03 0,04236851 ! signal complex assembly GO:0007172 41 17 1,000 7,079E-03 0,04226338 ! heart looping GO:0001947 30 17 1,000 7,079E-03 0,04215876 ! regulation of viral genome replication GO:0045069 28 17 1,000 7,079E-03 0,04205467 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 1,000 7,079E-03 0,04195109 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 7,079E-03 0,04184801 ! regulation of protein binding GO:0043393 33 17 1,000 7,079E-03 0,04174544 ! nucleobase metabolic process GO:0009112 37 17 1,000 7,079E-03 0,04164338 ! genitalia development GO:0048806 30 17 1,000 7,079E-03 0,04154181 ! neural crest cell migration GO:0001755 37 17 1,000 7,079E-03 0,04144073 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 7,079E-03 0,04134015 ! RNA 3'-end processing GO:0031123 34 17 1,000 7,079E-03 0,04124005 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 7,079E-03 0,04114044 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 7,412E-03 0,04297412 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 7,925E-03 0,04583414 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,925E-03 0,04572422 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 7,925E-03 0,04561484 ! epidermis morphogenesis GO:0048730 40 18 1,000 7,925E-03 0,04550597 ! glutamine metabolic process GO:0006541 29 18 1,000 7,925E-03 0,04539762 ! response to retinoic acid GO:0032526 26 18 1,000 7,925E-03 0,04528979 ! nerve development GO:0021675 28 18 1,000 7,925E-03 0,04518247 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 8,211E-03 0,04670335 ! forelimb morphogenesis GO:0035136 32 19 1,000 8,814E-03 0,05001303 ! pigmentation during development GO:0048066 41 19 1,000 8,814E-03 0,04989536 ! neuromuscular junction development GO:0007528 34 19 1,000 8,814E-03 0,04977823 ! G1 phase GO:0051318 40 19 1,000 8,814E-03 0,04966165 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 8,814E-03 0,04954562 ! lipid phosphorylation GO:0046834 35 19 1,000 8,814E-03 0,04943013 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 8,814E-03 0,04931518 ! response to vitamin A GO:0033189 27 19 1,000 8,814E-03 0,04920076 ! regulation of bone remodeling GO:0046850 137 57 2,000 9,058E-03 0,05044891 ! regulation of tissue remodeling GO:0034103 140 58 2,000 9,5E-03 0,05278874 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 9,745E-03 0,05402317 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,745E-03 0,05389898 ! response to vitamin GO:0033273 31 20 1,000 9,745E-03 0,05377536 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 9,745E-03 0,05365231 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,745E-03 0,05352981 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 0,01042157 0,05711687 ! regulation of heart contraction GO:0008016 110 60 2,000 0,01042157 0,05698705 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 0,01042157 0,05685783 ! kidney development GO:0001822 122 60 2,000 0,01042157 0,05672919 ! hindlimb morphogenesis GO:0035137 43 21 1,000 0,01071777 0,05820984 ! ovarian follicle development GO:0001541 35 21 1,000 0,01071777 0,05807874 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 0,01071777 0,05794822 ! oogenesis GO:0048477 36 21 1,000 0,01071777 0,05781829 ! DNA modification GO:0006304 34 21 1,000 0,01071777 0,05768894 ! response to cytokine stimulus GO:0034097 63 21 1,000 0,01071777 0,05756017 ! gut development GO:0048565 39 21 1,000 0,01071777 0,05743198 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 0,010901 0,05828399 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 0,01173176 0,06258672 ! regeneration GO:0031099 41 22 1,000 0,01173176 0,06244825 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 0,01173176 0,0623104 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 0,01173176 0,06217315 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 0,01173176 0,06203651 ! renal system process GO:0003014 41 22 1,000 0,01173176 0,06190046 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 0,01173176 0,06176501 ! positive regulation of B cell activation GO:0050871 38 22 1,000 0,01173176 0,06163015 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 0,01173176 0,06149588 ! protein stabilization GO:0050821 39 22 1,000 0,01173176 0,0613622 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 0,01189762 0,06209471 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 0,01241492 0,06465431 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 0,01278612 0,06644366 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01278612 0,06630046 ! response to ethanol GO:0045471 46 23 1,000 0,01278612 0,06615788 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 0,01278612 0,06601591 ! regulation of viral reproduction GO:0050792 38 23 1,000 0,01278612 0,06587455 ! platelet activation GO:0030168 37 23 1,000 0,01278612 0,06573379 ! nerve-nerve synaptic transmission GO:0007270 49 23 1,000 0,01278612 0,06559363 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 1,000 0,01278612 0,06545407 ! negative regulation of catabolic process GO:0009895 50 23 1,000 0,01278612 0,0653151 ! fatty acid biosynthetic process GO:0006633 124 66 2,000 0,01348774 0,06875318 ! extracellular matrix organization GO:0030198 133 66 2,000 0,01348774 0,06860782 ! secondary metabolic process GO:0019748 116 66 2,000 0,01348774 0,06846308 ! cell projection assembly GO:0030031 120 66 2,000 0,01348774 0,06831895 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01388021 0,07015921 ! multicellular organismal response to stress GO:0033555 49 24 1,000 0,01388021 0,07001213 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 0,01388021 0,06986566 ! lymphocyte proliferation GO:0046651 48 24 1,000 0,01388021 0,0697198 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01388021 0,06957455 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01388021 0,0694299 ! protein tetramerization GO:0051262 52 24 1,000 0,01388021 0,06928586 ! adaptive immune response GO:0002250 119 67 2,000 0,01404334 0,06995504 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 0,01501337 0,07463256 ! myelination GO:0042552 45 25 1,000 0,01501337 0,07447868 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 0,01501337 0,07432543 ! vasculogenesis GO:0001570 46 25 1,000 0,01501337 0,07417281 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01501337 0,07402082 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01501337 0,07386945 ! receptor metabolic process GO:0043112 46 25 1,000 0,01501337 0,07371869 ! neural crest cell development GO:0014032 54 25 1,000 0,01501337 0,07356855 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 0,01501337 0,07341902 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01501337 0,0732701 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 0,01501337 0,07312178 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 0,01501337 0,07297406 ! neural tube closure GO:0001843 49 25 1,000 0,01501337 0,07282694 GO:0060606|tube closure, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 0,01519312 0,0735506 ! molting cycle process GO:0022404 50 26 1,000 0,01618495 0,07819477 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 0,01618495 0,07803807 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01618495 0,07788199 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 0,01618495 0,07772654 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 0,01618495 0,0775717 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01618495 0,07741748 GO:0032943|mononuclear cell proliferation, ! humoral immune response GO:0006959 109 71 2,000 0,01639453 0,07826439 ! B cell activation GO:0042113 160 71 2,000 0,01639453 0,07810941 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 0,01701467 0,08090376 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 0,01701467 0,08074419 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01739433 0,08238339 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 0,01739433 0,08222153 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01739433 0,08206031 ! male gonad development GO:0008584 44 27 1,000 0,01739433 0,08189973 ! primary neural tube formation GO:0014020 51 27 1,000 0,01739433 0,08173977 ! base-excision repair GO:0006284 41 27 1,000 0,01739433 0,08158043 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01739433 0,08142171 ! glutathione metabolic process GO:0006749 39 27 1,000 0,01739433 0,08126361 ! dendrite development GO:0016358 59 28 1,000 0,01864087 0,0869185 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01895306 0,08820324 ! meiotic cell cycle GO:0051321 122 75 2,000 0,01895306 0,08803296 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01895306 0,08786334 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01962524 0,09080448 ! regulation of pH GO:0006885 43 29 1,000 0,01992396 0,0920097 ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01992396 0,09183344 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01992396 0,09165785 ! sterol biosynthetic process GO:0016126 52 29 1,000 0,01992396 0,09148293 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01992396 0,09130868 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01992396 0,09113509 ! tissue homeostasis GO:0001894 48 29 1,000 0,01992396 0,09096215 GO:0048871|multicellular organismal homeostasis, ! positive regulation of ligase activity GO:0051351 124 77 2,000 0,02031046 0,09255106 ! ensheathment of neurons GO:0007272 57 30 1,000 0,02124298 0,09661742 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 1,000 0,02124298 0,09643513 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,02259733 0,10239015 ! collagen metabolic process GO:0032963 45 31 1,000 0,02259733 0,10219769 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,02259733 0,10200594 ! ovulation cycle process GO:0022602 49 31 1,000 0,02259733 0,10181492 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,02259733 0,10162461 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,02259733 0,10143502 ! mesoderm formation GO:0001707 69 31 1,000 0,02259733 0,10124612 ! T cell activation GO:0042110 168 81 2,000 0,02318187 0,10367208 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,02318187 0,10347974 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,02393237 0,10663199 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,0239864 0,10667517 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,0239864 0,10647836 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,0239864 0,10628226 ! ovulation cycle GO:0042698 51 32 1,000 0,0239864 0,10608689 ! peripheral nervous system development GO:0007422 64 32 1,000 0,0239864 0,10589224 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,0239864 0,1056983 ! post-embryonic development GO:0009791 69 33 1,000 0,0254096 0,11176507 ! formation of primary germ layer GO:0001704 72 33 1,000 0,0254096 0,11156112 ! cell fate specification GO:0001708 52 33 1,000 0,0254096 0,11135791 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,0254096 0,11115544 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,02686635 0,11731476 ! glial cell differentiation GO:0010001 63 34 1,000 0,02686635 0,11710223 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,02686635 0,11689047 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,02686635 0,11667948 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,02686635 0,11646925 ! placenta development GO:0001890 53 34 1,000 0,02686635 0,11625977 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,02835606 0,12248598 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,02835606 0,12226647 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,02835606 0,12204775 ! odontogenesis GO:0042476 66 35 1,000 0,02835606 0,12182981 ! female gonad development GO:0008585 58 35 1,000 0,02835606 0,12161264 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,02835606 0,12139625 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02835606 0,12118062 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,02835606 0,12096576 ! neural tube formation GO:0001841 67 35 1,000 0,02835606 0,12075167 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,0295507 0,12561657 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02987818 0,12678465 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,02987818 0,12656144 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02987818 0,12633901 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02987818 0,12611736 ! embryonic organ development GO:0048568 57 36 1,000 0,02987818 0,12589649 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,03143212 0,13221273 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,03143212 0,131982 ! glycogen metabolic process GO:0005977 61 37 1,000 0,03143212 0,13175206 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,03143212 0,13152293 ! regulation of defense response GO:0031347 149 92 2,000 0,03215319 0,13430657 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,03301734 0,13767714 GO:0006956|complement activation, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,03301734 0,13743895 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 1,000 0,03301734 0,13720158 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,03301734 0,13696502 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,03301734 0,13672928 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,03301734 0,13649435 GO:0006073|cellular glucan metabolic process, ! transcription initiation GO:0006352 153 94 2,000 0,03395263 0,14012013 ! regulation of T cell activation GO:0050863 158 94 2,000 0,03395263 0,1398802 ! mammary gland development GO:0030879 86 39 1,000 0,03463327 0,14244043 ! organic ether metabolic process GO:0018904 55 39 1,000 0,03463327 0,14219736 ! segmentation GO:0035282 67 39 1,000 0,03463327 0,14195511 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,03463327 0,14171369 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,03463327 0,14147309 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,03463327 0,14123331 ! leukocyte differentiation GO:0002521 202 96 2,000 0,03580336 0,14575784 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,03627938 0,14744627 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,03627938 0,14719762 ! maintenance of protein location GO:0045185 91 40 1,000 0,03627938 0,14694981 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03696385 0,14947065 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03696385 0,14921986 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03696385 0,14896991 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03696385 0,14872079 ! neuron fate determination GO:0048664 7 5 0,000 0,03696385 0,14847251 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03696385 0,14822506 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03696385 0,14797843 ! polyol transport GO:0015791 12 5 0,000 0,03696385 0,14773262 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03696385 0,14748762 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03696385 0,14724343 ! response to superoxide GO:0000303 10 5 0,000 0,03696385 0,14700006 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03696385 0,14675748 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03696385 0,14651571 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03696385 0,14627473 ! female meiosis GO:0007143 7 5 0,000 0,03696385 0,14603454 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03696385 0,14579514 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03696385 0,14555652 ! cobalt ion transport GO:0006824 11 5 0,000 0,03696385 0,14531868 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03696385 0,14508162 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03696385 0,14484533 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03696385 0,14460981 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03696385 0,14437506 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03696385 0,14414106 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03696385 0,14390782 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03696385 0,14367534 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03696385 0,1434436 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03696385 0,14321262 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03696385 0,14298237 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03696385 0,14275286 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03696385 0,14252409 ! negative chemotaxis GO:0050919 14 5 0,000 0,03696385 0,14229606 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03696385 0,14206875 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03696385 0,14184216 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03696385 0,1416163 ! behavioral response to pain GO:0048266 9 5 0,000 0,03696385 0,14139115 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03696385 0,14116672 ! Notch receptor processing GO:0007220 8 5 0,000 0,03696385 0,140943 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03696385 0,14071999 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03696385 0,14049768 ! micturition GO:0060073 9 5 0,000 0,03696385 0,14027608 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03696385 0,14005517 ! copulation GO:0007620 9 5 0,000 0,03696385 0,13983496 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03696385 0,13961544 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03696385 0,13939661 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03696385 0,13917846 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03696385 0,13896099 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03696385 0,1387442 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03696385 0,13852809 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03696385 0,13831265 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03696385 0,13809788 ! grooming behavior GO:0007625 6 5 0,000 0,03696385 0,13788377 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03696385 0,13767033 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03696385 0,13745755 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03696385 0,13724542 ! response to protozoan GO:0001562 10 5 0,000 0,03696385 0,13703395 ! lymph vessel development GO:0001945 10 5 0,000 0,03696385 0,13682313 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03696385 0,13661296 ! endochondral ossification GO:0001958 16 5 0,000 0,03696385 0,13640343 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03696385 0,13619454 ! parathyroid gland development GO:0060017 13 5 0,000 0,03696385 0,13598629 ! anagen GO:0042640 6 5 0,000 0,03696385 0,13577868 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03696385 0,1355717 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03696385 0,13536535 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03696385 0,13515963 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03696385 0,13495453 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03696385 0,13475005 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03696385 0,13454619 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03696385 0,13434295 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03696385 0,13414032 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03696385 0,13393831 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03696385 0,13373689 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03696385 0,13353609 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03696385 0,13333588 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03696385 0,13313628 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03696385 0,13293727 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03696385 0,13273886 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03696385 0,13254104 ! histidine catabolic process GO:0006548 6 5 0,000 0,03696385 0,1323438 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03696385 0,13214715 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03696385 0,13195109 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03696385 0,13175561 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03696385 0,1315607 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03696385 0,13136637 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03696385 0,13117262 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03696385 0,13097943 ! polyol catabolic process GO:0046174 7 5 0,000 0,03696385 0,13078682 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03696385 0,13059476 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03696385 0,13040328 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03696385 0,13021235 ! muscle cell migration GO:0014812 8 5 0,000 0,03696385 0,13002198 ! mitochondrial fission GO:0000266 8 5 0,000 0,03696385 0,12983217 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03696385 0,12964291 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03696385 0,1294542 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03696385 0,12926604 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03696385 0,12907842 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03696385 0,12889135 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03696385 0,12870483 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03696385 0,12851884 ! response to food GO:0032094 6 5 0,000 0,03696385 0,12833338 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03696385 0,12814846 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03696385 0,12796408 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03696385 0,12778022 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03696385 0,12759689 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,03696385 0,12741409 ! forebrain neuron development GO:0021884 13 5 0,000 0,03696385 0,12723181 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03696385 0,12705005 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03696385 0,12686881 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03696385 0,12668808 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03696385 0,12650787 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03696385 0,12632817 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03696385 0,12614899 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03696385 0,1259703 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03696385 0,12579213 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03696385 0,12561446 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03696385 0,12543728 ! basic amino acid transport GO:0015802 11 5 0,000 0,03696385 0,12526061 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03696385 0,12508444 ! depyrimidination GO:0045008 10 5 0,000 0,03696385 0,12490876 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03696385 0,12473357 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03696385 0,12455887 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03696385 0,12438466 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,03696385 0,12421094 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03696385 0,12403771 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03696385 0,12386495 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03696385 0,12369268 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03696385 0,12352088 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03696385 0,12334956 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03696385 0,12317872 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03696385 0,12300835 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03696385 0,12283845 ! response to arsenic GO:0046685 10 5 0,000 0,03696385 0,12266901 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03696385 0,12250005 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03696385 0,12233155 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03696385 0,12216351 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03696385 0,12199593 ! response to cadmium ion GO:0046686 7 5 0,000 0,03696385 0,12182881 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03696385 0,12166215 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03696385 0,12149595 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03696385 0,1213302 ! decidualization GO:0046697 11 5 0,000 0,03696385 0,1211649 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03696385 0,12100005 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03696385 0,12083564 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03696385 0,12067169 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03696385 0,12050818 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03696385 0,12034511 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03696385 0,12018248 ! neural tube patterning GO:0021532 7 5 0,000 0,03696385 0,12002029 ! embryonic cleavage GO:0040016 6 5 0,000 0,03696385 0,11985854 ! peroxisome fission GO:0016559 5 5 0,000 0,03696385 0,11969722 ! histone demethylation GO:0016577 10 5 0,000 0,03696385 0,11953634 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03696385 0,11937589 ! mitotic recombination GO:0006312 9 5 0,000 0,03696385 0,11921586 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03696385 0,11905627 ! metaphase plate congression GO:0051310 7 5 0,000 0,03696385 0,11889711 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03696385 0,11873836 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03696385 0,11858005 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03696385 0,11842215 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03696385 0,11826467 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03696385 0,11810762 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03696385 0,11795097 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03696385 0,11779475 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03696385 0,11763893 ! plasminogen activation GO:0031639 5 5 0,000 0,03696385 0,11748353 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03696385 0,11732854 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03696385 0,11717396 ! metaphase GO:0051323 8 5 0,000 0,03696385 0,11701978 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03696385 0,11686601 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03696385 0,11671264 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03696385 0,11655968 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03696385 0,11640711 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03696385 0,11625495 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03696385 0,11610318 ! response to redox state GO:0051775 5 5 0,000 0,03696385 0,11595181 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03696385 0,11580083 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03696385 0,11565024 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03696385 0,11550004 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03696385 0,11535024 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03696385 0,11520082 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03696385 0,11505179 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03696385 0,11490315 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03696385 0,11475488 ! striatum development GO:0021756 9 5 0,000 0,03696385 0,114607 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03696385 0,1144595 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03696385 0,11431238 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03696385 0,11416564 ! glial cell migration GO:0008347 11 5 0,000 0,03696385 0,11401928 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03696385 0,11387328 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03696385 0,11372767 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03696385 0,11358242 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03696385 0,11343754 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03696385 0,11329304 ! neuroprotection GO:0043526 6 5 0,000 0,03696385 0,1131489 ! neural plate development GO:0001840 8 5 0,000 0,03696385 0,11300513 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03696385 0,11286172 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03696385 0,11271868 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03696385 0,11257599 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03696385 0,11243367 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03696385 0,11229171 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03696385 0,11215011 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03696385 0,11200886 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03696385 0,11186797 ! spindle assembly GO:0051225 6 5 0,000 0,03696385 0,11172743 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03696385 0,11158725 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03696385 0,11144741 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03696385 0,11130793 ! drug metabolic process GO:0017144 6 5 0,000 0,03696385 0,11116879 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03696385 0,11103001 ! organ regeneration GO:0031100 7 5 0,000 0,03696385 0,11089156 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03696385 0,11075347 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03696385 0,11061571 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03696385 0,1104783 ! response to virus GO:0009615 160 98 2,000 0,03770511 0,11255396 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,03795512 0,11315988 ! gliogenesis GO:0042063 88 41 1,000 0,03795512 0,11301983 ! female gamete generation GO:0007292 61 41 1,000 0,03795512 0,11288013 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,03795512 0,11274077 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,03867503 0,1147375 GO:0060538|skeletal muscle organ development, ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03965997 0,11751463 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03965997 0,11737009 ! neuron migration GO:0001764 79 42 1,000 0,03965997 0,1172259 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,04139338 0,12219936 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,04139338 0,12204961 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,04139338 0,12190022 ! neural tube development GO:0021915 77 43 1,000 0,04139338 0,1217512 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,04315486 0,12677727 ! double-strand break repair GO:0006302 81 44 1,000 0,04315486 0,12662266 ! biopolymer methylation GO:0043414 84 44 1,000 0,04315486 0,12646843 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,04315486 0,12631458 ! developmental growth GO:0048589 82 44 1,000 0,04315486 0,1261611 ! maintenance of location in cell GO:0051651 97 44 1,000 0,04315486 0,12600799 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04419174 0,12887919 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04419174 0,12872316 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04419174 0,12856751 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04419174 0,12841224 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04419174 0,12825734 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04419174 0,12810281 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04419174 0,12794866 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04419174 0,12779487 ! sleep GO:0030431 13 6 0,000 0,04419174 0,12764146 ! response to oxygen radical GO:0000305 11 6 0,000 0,04419174 0,12748841 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04419174 0,12733573 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04419174 0,12718341 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04419174 0,12703146 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04419174 0,12687987 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04419174 0,12672865 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04419174 0,12657778 ! forebrain regionalization GO:0021871 8 6 0,000 0,04419174 0,12642727 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04419174 0,12627712 ! male meiosis GO:0007140 7 6 0,000 0,04419174 0,12612732 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04419174 0,12597788 ! response to zinc ion GO:0010043 9 6 0,000 0,04419174 0,1258288 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04419174 0,12568006 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04419174 0,12553168 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04419174 0,12538365 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04419174 0,12523596 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04419174 0,12508863 ! malate metabolic process GO:0006108 11 6 0,000 0,04419174 0,12494164 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04419174 0,12479499 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04419174 0,12464869 ! protein refolding GO:0042026 15 6 0,000 0,04419174 0,12450273 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04419174 0,12435712 ! opsonization GO:0008228 8 6 0,000 0,04419174 0,12421184 ! mating behavior GO:0007617 7 6 0,000 0,04419174 0,1240669 ! neuron remodeling GO:0016322 15 6 0,000 0,04419174 0,1239223 ! erythrocyte maturation GO:0043249 7 6 0,000 0,04419174 0,12377804 ! equilibrioception GO:0050957 14 6 0,000 0,04419174 0,12363411 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04419174 0,12349052 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04419174 0,12334725 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04419174 0,12320433 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,04419174 0,12306173 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04419174 0,12291946 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04419174 0,12277752 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04419174 0,12263591 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04419174 0,12249462 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04419174 0,12235366 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04419174 0,12221303 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,04419174 0,12207271 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04419174 0,12193272 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,04419174 0,12179305 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04419174 0,1216537 ! thymic T cell selection GO:0045061 12 6 0,000 0,04419174 0,12151467 ! protein lipoylation GO:0009249 10 6 0,000 0,04419174 0,12137595 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04419174 0,12123755 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04419174 0,12109947 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04419174 0,1209617 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04419174 0,12082424 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04419174 0,1206871 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,04419174 0,12055026 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,04419174 0,12041374 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04419174 0,12027753 ! hyperosmotic response GO:0006972 9 6 0,000 0,04419174 0,12014162 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04419174 0,12000602 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04419174 0,11987073 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04419174 0,11973574 ! urea metabolic process GO:0019627 7 6 0,000 0,04419174 0,11960105 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04419174 0,11946667 ! neutrophil activation GO:0042119 8 6 0,000 0,04419174 0,11933259 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04419174 0,1191988 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04419174 0,11906532 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04419174 0,11893214 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04419174 0,11879926 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04419174 0,11866667 ! nucleoside salvage GO:0043174 9 6 0,000 0,04419174 0,11853437 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04419174 0,11840238 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04419174 0,11827067 ! male sex determination GO:0030238 15 6 0,000 0,04419174 0,11813926 ! carnitine transport GO:0015879 10 6 0,000 0,04419174 0,11800814 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04419174 0,11787731 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04419174 0,11774677 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04419174 0,11761652 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04419174 0,11748656 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04419174 0,11735688 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,04419174 0,11722749 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04419174 0,11709838 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,04419174 0,11696956 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04419174 0,11684103 ! establishment of spindle localization GO:0051293 12 6 0,000 0,04419174 0,11671277 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04419174 0,1165848 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,04419174 0,1164571 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,04419174 0,11632969 ! response to UV-C GO:0010225 11 6 0,000 0,04419174 0,11620255 ! astrocyte development GO:0014002 15 6 0,000 0,04419174 0,11607569 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04419174 0,11594911 ! interaction with symbiont GO:0051702 13 6 0,000 0,04419174 0,1158228 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04419174 0,11569677 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04419174 0,11557101 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04419174 0,11544553 ! response to copper ion GO:0046688 10 6 0,000 0,04419174 0,11532032 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04419174 0,11519538 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,04419174 0,11507071 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04419174 0,11494631 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04419174 0,11482217 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04419174 0,11469831 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04419174 0,11457471 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04419174 0,11445138 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04419174 0,11432832 ! hair follicle maturation GO:0048820 7 6 0,000 0,04419174 0,11420551 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04419174 0,11408298 ! Schwann cell development GO:0014044 15 6 0,000 0,04419174 0,1139607 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04419174 0,11383869 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04419174 0,11371693 ! subpallium development GO:0021544 10 6 0,000 0,04419174 0,11359544 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04419174 0,11347421 ! histone ubiquitination GO:0016574 8 6 0,000 0,04419174 0,11335323 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04419174 0,11323252 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04419174 0,11311206 ! G2 phase GO:0051319 16 6 0,000 0,04419174 0,11299185 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04419174 0,1128719 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04419174 0,11275221 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04419174 0,11263277 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04419174 0,11251358 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04419174 0,11239464 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04419174 0,11227596 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04419174 0,11215752 ! receptor internalization GO:0031623 10 6 0,000 0,04419174 0,11203934 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,04419174 0,1119214 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,04419174 0,11180372 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04419174 0,11168627 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,04419174 0,11156908 ! protein deubiquitination GO:0016579 14 6 0,000 0,04419174 0,11145213 ! protein destabilization GO:0031648 9 6 0,000 0,04419174 0,11133543 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04419174 0,11121897 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04419174 0,11110275 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04419174 0,11098678 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04419174 0,11087105 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04419174 0,11075556 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04419174 0,11064031 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04419174 0,11052529 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04419174 0,11041052 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04419174 0,11029599 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04419174 0,11018169 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04419174 0,11006763 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04419174 0,10995381 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04419174 0,10984022 ! catecholamine transport GO:0051937 9 6 0,000 0,04419174 0,10972687 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04419174 0,10961375 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04419174 0,10950086 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04419174 0,1093882 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04419174 0,10927578 ! maternal placenta development GO:0001893 12 6 0,000 0,04419174 0,10916359 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04419174 0,10905162 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04419174 0,10893989 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04419174 0,10882839 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04419174 0,10871711 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04419174 0,10860606 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04419174 0,10849524 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,04494387 0,1102293 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,04494387 0,11011705 ! response to insulin stimulus GO:0032868 95 46 1,000 0,04675991 0,11444998 ! endosome transport GO:0016197 108 47 1,000 0,04860247 0,11883898 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,04860247 0,11871833 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,04860247 0,11859792 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,04860247 0,11847776 ! methylation GO:0032259 90 47 1,000 0,04860247 0,11835785 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,05047107 0,12278403 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,05047107 0,12266001 ! tRNA transcription GO:0009304 14 7 0,000 0,05136562 0,12470806 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,05136562 0,12458234 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,05136562 0,12445688 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,05136562 0,12433168 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,05136562 0,12420672 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,05136562 0,12408201 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,05136562 0,12395756 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,05136562 0,12383335 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,05136562 0,1237094 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,05136562 0,12358569 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05136562 0,12346222 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,05136562 0,12333901 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,05136562 0,12321604 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05136562 0,12309331 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,05136562 0,12297083 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,05136562 0,12284859 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,05136562 0,1227266 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,05136562 0,12260485 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,05136562 0,12248334 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,05136562 0,12236207 ! glycolipid transport GO:0046836 10 7 0,000 0,05136562 0,12224103 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,05136562 0,12212024 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,05136562 0,12199969 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,05136562 0,12187937 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,05136562 0,1217593 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,05136562 0,12163945 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,05136562 0,12151985 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,05136562 0,12140048 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,05136562 0,12128134 ! pericardium development GO:0060039 14 7 0,000 0,05136562 0,12116244 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,05136562 0,12104377 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,05136562 0,12092533 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05136562 0,12080712 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,05136562 0,12068915 ! lipoprotein transport GO:0042953 14 7 0,000 0,05136562 0,1205714 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05136562 0,12045389 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05136562 0,1203366 ! rhythmic behavior GO:0007622 15 7 0,000 0,05136562 0,12021954 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,05136562 0,12010271 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,05136562 0,1199861 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,05136562 0,11986972 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,05136562 0,11975357 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,05136562 0,11963764 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,05136562 0,11952194 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,05136562 0,11940646 ! mechanosensory behavior GO:0007638 14 7 0,000 0,05136562 0,1192912 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,05136562 0,11917617 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05136562 0,11906135 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,05136562 0,11894676 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05136562 0,11883239 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05136562 0,11871824 ! spinal cord patterning GO:0021511 13 7 0,000 0,05136562 0,11860431 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,05136562 0,11849059 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,05136562 0,11837709 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,05136562 0,11826381 ! adrenal gland development GO:0030325 17 7 0,000 0,05136562 0,11815075 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,05136562 0,1180379 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,05136562 0,11792527 ! ovulation GO:0030728 9 7 0,000 0,05136562 0,11781286 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,05136562 0,11770065 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,05136562 0,11758866 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,05136562 0,11747689 ! microtubule nucleation GO:0007020 20 7 0,000 0,05136562 0,11736532 ! proline biosynthetic process GO:0006561 10 7 0,000 0,05136562 0,11725397 ! thyroid hormone generation GO:0006590 13 7 0,000 0,05136562 0,11714283 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,05136562 0,1170319 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,05136562 0,11692118 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,05136562 0,11681067 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05136562 0,11670036 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05136562 0,11659027 ! galactose metabolic process GO:0006012 13 7 0,000 0,05136562 0,11648038 ! vesicle fusion GO:0006906 17 7 0,000 0,05136562 0,1163707 ! response to dietary excess GO:0002021 8 7 0,000 0,05136562 0,11626123 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,05136562 0,11615196 ! intracellular pH reduction GO:0051452 11 7 0,000 0,05136562 0,1160429 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,05136562 0,11593404 ! purine salvage GO:0043101 10 7 0,000 0,05136562 0,11582539 ! nucleoside transport GO:0015858 8 7 0,000 0,05136562 0,11571693 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,05136562 0,11560869 ! parturition GO:0007567 14 7 0,000 0,05136562 0,11550064 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,05136562 0,1153928 ! rRNA modification GO:0000154 14 7 0,000 0,05136562 0,11528515 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,05136562 0,11517771 ! spindle checkpoint GO:0031577 15 7 0,000 0,05136562 0,11507047 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,05136562 0,11496343 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,05136562 0,11485659 ! macrophage differentiation GO:0030225 11 7 0,000 0,05136562 0,11474994 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05136562 0,11464349 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,05136562 0,11453724 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,05136562 0,11443119 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,05136562 0,11432533 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,05136562 0,11421967 ! eating behavior GO:0042755 7 7 0,000 0,05136562 0,11411421 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,05136562 0,11400894 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,05136562 0,11390386 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,05136562 0,11379897 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,05136562 0,11369428 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,05136562 0,11358978 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,05136562 0,11348548 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,05136562 0,11338136 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,05136562 0,11327744 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,05136562 0,11317371 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,05136562 0,11307016 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,05136562 0,11296681 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,05136562 0,11286364 ! regulation of meiosis GO:0040020 12 7 0,000 0,05136562 0,11276066 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,05136562 0,11265787 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,05136562 0,11255527 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,05136562 0,11245285 ! transcription termination GO:0006353 13 7 0,000 0,05136562 0,11235062 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,05136562 0,11224858 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,05136562 0,11214672 ! anaphase GO:0051322 17 7 0,000 0,05136562 0,11204505 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,05136562 0,11194356 ! axonal fasciculation GO:0007413 18 7 0,000 0,05136562 0,11184225 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,05136562 0,11174113 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,05136562 0,11164019 ! diuresis GO:0030146 12 7 0,000 0,05136562 0,11153943 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,05136562 0,11143885 ! thiamin metabolic process GO:0006772 7 7 0,000 0,05136562 0,11133846 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05136562 0,11123824 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,05136562 0,11113821 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,05136562 0,11103835 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,05136562 0,11093868 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05136562 0,11083918 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05136562 0,11073986 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05136562 0,11064072 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,05136562 0,11054176 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,05136562 0,11044297 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,05136562 0,11034436 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,05136562 0,11024593 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,05136562 0,11014767 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05136562 0,11004959 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,05136562 0,10995168 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,05136562 0,10985394 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,05136562 0,10975638 ! adult feeding behavior GO:0008343 9 7 0,000 0,05136562 0,10965899 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,05136562 0,10956178 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,05136562 0,10946474 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,05136562 0,10936786 ! muscle adaptation GO:0043500 14 7 0,000 0,05136562 0,10927116 ! embryonic heart tube development GO:0035050 10 7 0,000 0,05136562 0,10917463 ! retina homeostasis GO:0001895 12 7 0,000 0,05136562 0,10907828 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,05136562 0,10898209 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,05136562 0,10888607 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,05136562 0,10879022 ! protein prenylation GO:0018342 18 7 0,000 0,05136562 0,10869453 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,05136562 0,10859902 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,05136562 0,10850368 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05136562 0,1084085 ! regulation of action potential GO:0001508 95 49 1,000 0,05236522 0,11042131 ! peptide metabolic process GO:0006518 76 49 1,000 0,05236522 0,11032461 ! response to temperature stimulus GO:0009266 76 49 1,000 0,05236522 0,11022809 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,05236522 0,11013174 GO:0019724|B cell mediated immunity, ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,05236522 0,11003555 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,05236522 0,10993954 ! regulation of ossification GO:0030278 117 50 1,000 0,05428441 0,11386948 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,05428441 0,1137703 ! inner ear development GO:0048839 79 50 1,000 0,05428441 0,11367128 ! histone modification GO:0016570 91 50 1,000 0,05428441 0,11357243 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,05428441 0,11347376 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,05428441 0,11337526 ! positive regulation of binding GO:0051099 78 51 1,000 0,05622819 0,11733306 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,05622819 0,11723139 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,05622819 0,11712989 ! chromatin remodeling GO:0006338 109 51 1,000 0,05622819 0,11702857 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,05622819 0,11692742 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,05622819 0,11682644 ! vesicle organization GO:0016050 107 51 1,000 0,05622819 0,11672564 ! covalent chromatin modification GO:0016569 101 52 1,000 0,05819607 0,12070667 ! synapse organization GO:0050808 85 52 1,000 0,05819607 0,1206027 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05848589 0,12109902 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05848589 0,12099489 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,05848589 0,12089094 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05848589 0,12078717 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05848589 0,12068358 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05848589 0,12058017 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05848589 0,12047693 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05848589 0,12037387 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05848589 0,12027099 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05848589 0,12016828 ! meiotic prophase I GO:0007128 13 8 0,000 0,05848589 0,12006575 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05848589 0,11996339 ! oligopeptide transport GO:0006857 15 8 0,000 0,05848589 0,11986121 ! UTP metabolic process GO:0046051 8 8 0,000 0,05848589 0,1197592 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05848589 0,11965736 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05848589 0,1195557 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05848589 0,11945421 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05848589 0,11935289 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05848589 0,11925174 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05848589 0,11915077 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05848589 0,11904997 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05848589 0,11894933 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05848589 0,11884887 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05848589 0,11874857 ! reflex GO:0060004 16 8 0,000 0,05848589 0,11864845 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05848589 0,11854849 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05848589 0,1184487 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05848589 0,11834908 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05848589 0,11824963 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05848589 0,11815034 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05848589 0,11805122 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05848589 0,11795227 ! histidine metabolic process GO:0006547 16 8 0,000 0,05848589 0,11785348 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05848589 0,11775486 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05848589 0,1176564 ! glycine catabolic process GO:0006546 13 8 0,000 0,05848589 0,11755811 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05848589 0,11745998 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05848589 0,11736202 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05848589 0,11726422 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05848589 0,11716658 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05848589 0,1170691 ! macrophage activation GO:0042116 12 8 0,000 0,05848589 0,11697179 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05848589 0,11687463 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05848589 0,11677764 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05848589 0,11668081 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05848589 0,11658414 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05848589 0,11648763 ! osteoblast development GO:0002076 16 8 0,000 0,05848589 0,11639128 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05848589 0,11629509 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05848589 0,11619906 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05848589 0,11610318 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05848589 0,11600747 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05848589 0,11591191 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05848589 0,11581651 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05848589 0,11572127 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05848589 0,11562618 ! intermediate filament organization GO:0045109 12 8 0,000 0,05848589 0,11553125 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05848589 0,11543647 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05848589 0,11534185 ! cellular extravasation GO:0045123 12 8 0,000 0,05848589 0,11524739 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05848589 0,11515308 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05848589 0,11505892 ! response to antibiotic GO:0046677 11 8 0,000 0,05848589 0,11496492 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05848589 0,11487107 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05848589 0,11477737 ! DNA topological change GO:0006265 12 8 0,000 0,05848589 0,11468383 ! response to tropane GO:0014073 15 8 0,000 0,05848589 0,11459044 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05848589 0,1144972 ! melanosome transport GO:0032402 13 8 0,000 0,05848589 0,11440411 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05848589 0,11431118 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05848589 0,11421839 ! mast cell activation GO:0045576 14 8 0,000 0,05848589 0,11412576 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05848589 0,11403327 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05848589 0,11394094 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05848589 0,11384875 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05848589 0,11375672 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05848589 0,11366483 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05848589 0,11357309 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05848589 0,1134815 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05848589 0,11339006 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05848589 0,11329876 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05848589 0,11320761 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05848589 0,11311661 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05848589 0,11302575 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05848589 0,11293504 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05848589 0,11284447 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05848589 0,11275405 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05848589 0,11266378 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05848589 0,11257365 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05848589 0,11248366 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05848589 0,11239382 ! hormone catabolic process GO:0042447 17 8 0,000 0,05848589 0,11230412 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05848589 0,11221456 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05848589 0,11212515 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05848589 0,11203587 ! ATP catabolic process GO:0006200 11 8 0,000 0,05848589 0,11194675 ! blastocyst growth GO:0001832 19 8 0,000 0,05848589 0,11185776 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05848589 0,11176891 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05848589 0,11168021 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05848589 0,11159164 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05848589 0,11150322 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05848589 0,11141493 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05848589 0,11132679 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05848589 0,11123878 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05848589 0,11115092 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05848589 0,11106319 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05848589 0,1109756 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05848589 0,11088815 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05848589 0,11080083 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05848589 0,11071366 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05848589 0,11062662 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05848589 0,11053972 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,06018758 0,11366666 ! cell maturation GO:0048469 100 53 1,000 0,06018758 0,11357751 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,06220227 0,11728736 ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,06220227 0,11719551 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,06423968 0,1209395 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,06423968 0,12084494 ! gastrulation GO:0007369 112 55 1,000 0,06423968 0,12075053 ! heart morphogenesis GO:0003007 97 55 1,000 0,06423968 0,12065627 ! RNA elongation GO:0006354 79 55 1,000 0,06423968 0,12056215 ! regulation of developmental growth GO:0048638 15 9 0,000 0,06555296 0,12293095 ! axon extension GO:0048675 15 9 0,000 0,06555296 0,12283521 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,06555296 0,12273962 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,06555296 0,12264418 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,06555296 0,12254888 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06555296 0,12245374 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,06555296 0,12235874 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,06555296 0,12226388 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,06555296 0,12216918 ! phosphate transport GO:0006817 19 9 0,000 0,06555296 0,12207462 ! reproductive behavior GO:0019098 19 9 0,000 0,06555296 0,12198021 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06555296 0,12188594 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,06555296 0,12179182 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06555296 0,12169785 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,06555296 0,12160402 ! GTP metabolic process GO:0046039 9 9 0,000 0,06555296 0,12151033 ! RNA methylation GO:0001510 15 9 0,000 0,06555296 0,12141679 ! elastic fiber assembly GO:0048251 15 9 0,000 0,06555296 0,12132339 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,06555296 0,12123014 ! artery development GO:0060840 24 9 0,000 0,06555296 0,12113703 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,06555296 0,12104406 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,06555296 0,12095124 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,06555296 0,12085855 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,06555296 0,12076601 ! chemosensory behavior GO:0007635 20 9 0,000 0,06555296 0,12067361 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,06555296 0,12058135 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06555296 0,12048924 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,06555296 0,12039726 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,06555296 0,12030542 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,06555296 0,12021373 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06555296 0,12012217 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06555296 0,12003075 ! protein targeting to ER GO:0045047 22 9 0,000 0,06555296 0,11993948 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,06555296 0,11984834 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,06555296 0,11975734 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,06555296 0,11966647 ! endosome organization GO:0007032 17 9 0,000 0,06555296 0,11957575 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06555296 0,11948516 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06555296 0,11939471 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06555296 0,1193044 ! mannose metabolic process GO:0006013 13 9 0,000 0,06555296 0,11921422 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,06555296 0,11912418 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,06555296 0,11903427 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,06555296 0,1189445 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,06555296 0,11885487 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06555296 0,11876537 ! ruffle organization GO:0031529 15 9 0,000 0,06555296 0,11867601 ! retinol metabolic process GO:0042572 18 9 0,000 0,06555296 0,11858678 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,06555296 0,11849768 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,06555296 0,11840872 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,06555296 0,11831989 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,06555296 0,11823119 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,06555296 0,11814263 ! oligodendrocyte development GO:0014003 10 9 0,000 0,06555296 0,1180542 ! segment specification GO:0007379 13 9 0,000 0,06555296 0,1179659 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06555296 0,11787774 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,06555296 0,1177897 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06555296 0,1177018 ! response to amine stimulus GO:0014075 13 9 0,000 0,06555296 0,11761403 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06555296 0,11752639 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,06555296 0,11743888 ! erythrocyte development GO:0048821 15 9 0,000 0,06555296 0,1173515 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06555296 0,11726425 ! renal water homeostasis GO:0003091 14 9 0,000 0,06555296 0,11717713 ! postreplication repair GO:0006301 22 9 0,000 0,06555296 0,11709013 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,06555296 0,11700327 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,06555296 0,11691654 ! icosanoid secretion GO:0032309 15 9 0,000 0,06555296 0,11682993 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,06555296 0,11674346 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06555296 0,11665711 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,06555296 0,11657089 ! regulation of cell division GO:0051302 15 9 0,000 0,06555296 0,11648479 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,06555296 0,11639883 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,06555296 0,11631299 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06555296 0,11622727 ! sterol catabolic process GO:0016127 11 9 0,000 0,06555296 0,11614169 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06555296 0,11605623 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,06555296 0,11597089 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,06555296 0,11588568 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,06555296 0,1158006 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,06555296 0,11571564 ! musculoskeletal movement GO:0050881 14 9 0,000 0,06555296 0,1156308 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,06555296 0,11554609 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,06555296 0,1154615 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,06555296 0,11537704 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,06555296 0,1152927 ! pigment granule transport GO:0051904 17 9 0,000 0,06555296 0,11520848 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,06555296 0,11512439 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,06555296 0,11504042 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06555296 0,11495657 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06555296 0,11487284 ! mitochondrion localization GO:0051646 15 9 0,000 0,06555296 0,11478924 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,06629936 0,11601183 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,06629936 0,11592751 ! muscle fiber development GO:0048747 112 57 1,000 0,06838086 0,11948028 ! lipid modification GO:0030258 97 57 1,000 0,06838086 0,11939357 ! maintenance of location GO:0051235 118 57 1,000 0,06838086 0,11930699 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,07256721 0,12651935 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,07256721 0,12642773 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,07256721 0,12633625 ! synapsis GO:0007129 13 10 0,000 0,07256721 0,1262449 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,07256721 0,12615368 ! N-glycan processing GO:0006491 20 10 0,000 0,07256721 0,1260626 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,07256721 0,12597164 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,07256721 0,12588082 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,07256721 0,12579013 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,07256721 0,12569957 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,07256721 0,12560913 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,07256721 0,12551883 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,07256721 0,12542866 ! androgen metabolic process GO:0008209 17 10 0,000 0,07256721 0,12533862 ! phospholipid efflux GO:0033700 16 10 0,000 0,07256721 0,12524871 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,07256721 0,12515892 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,07256721 0,12506927 ! pathogenesis GO:0009405 13 10 0,000 0,07256721 0,12497974 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07256721 0,12489034 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,07256721 0,12480107 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,07256721 0,12471193 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,07256721 0,12462291 ! endoderm development GO:0007492 16 10 0,000 0,07256721 0,12453402 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,07256721 0,12444526 ! arginine catabolic process GO:0006527 13 10 0,000 0,07256721 0,12435662 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,07256721 0,12426811 ! proline metabolic process GO:0006560 13 10 0,000 0,07256721 0,12417973 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,07256721 0,12409147 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,07256721 0,12400334 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,07256721 0,12391533 ! V(D)J recombination GO:0033151 28 10 0,000 0,07256721 0,12382744 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07256721 0,12373969 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,07256721 0,12365205 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,07256721 0,12356454 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,07256721 0,12347715 ! multicellular organism growth GO:0035264 18 10 0,000 0,07256721 0,12338989 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,07256721 0,12330275 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,07256721 0,12321573 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,07256721 0,12312884 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,07256721 0,12304207 ! macroautophagy GO:0016236 17 10 0,000 0,07256721 0,12295542 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,07256721 0,12286889 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,07256721 0,12278249 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,07256721 0,1226962 ! copper ion homeostasis GO:0055070 13 10 0,000 0,07256721 0,12261004 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,07256721 0,122524 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,07256721 0,12243808 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,07256721 0,12235228 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,07256721 0,12226659 ! blastoderm segmentation GO:0007350 18 10 0,000 0,07256721 0,12218103 ! response to dsRNA GO:0043331 20 10 0,000 0,07256721 0,12209559 ! DNA ligation GO:0006266 19 10 0,000 0,07256721 0,12201027 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07256721 0,12192507 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,07256721 0,12183998 ! melanosome localization GO:0032400 16 10 0,000 0,07256721 0,12175502 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,07256721 0,12167017 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,07256721 0,12158544 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,07256721 0,12150083 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,07256721 0,12141634 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,07256721 0,12133196 ! mRNA cleavage GO:0006379 17 10 0,000 0,07256721 0,12124771 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,07256721 0,12116356 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07256721 0,12107954 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,07256721 0,12099563 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,07256721 0,12091184 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,07256721 0,12082816 ! salivary gland development GO:0007431 27 10 0,000 0,07256721 0,1207446 ! prophase GO:0051324 15 10 0,000 0,07256721 0,12066116 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07256721 0,12057783 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,07256721 0,12049461 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,07256721 0,12041151 ! midbrain development GO:0030901 13 10 0,000 0,07256721 0,12032853 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07256721 0,12024566 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,07256721 0,1201629 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,07256721 0,12008026 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,07256721 0,11999773 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,07256721 0,11991531 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,07256721 0,11983301 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,07256721 0,11975082 ! detection of calcium ion GO:0005513 23 10 0,000 0,07256721 0,11966874 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,07256721 0,11958678 ! blastocyst formation GO:0001825 17 10 0,000 0,07256721 0,11950493 ! cerebellar cortex development GO:0021695 15 10 0,000 0,07256721 0,11942318 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,07256721 0,11934156 ! activation of innate immune response GO:0002218 12 10 0,000 0,07256721 0,11926004 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,07256721 0,11917863 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,07256721 0,11909734 ! establishment of cell polarity GO:0030010 16 10 0,000 0,07256721 0,11901615 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,07256721 0,11893508 ! localization within membrane GO:0051668 20 10 0,000 0,07256721 0,11885412 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,07260756 0,11883932 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,07260756 0,11875853 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,07475191 0,12218281 ! mesoderm development GO:0007498 119 61 1,000 0,07691635 0,12563526 ! gonad development GO:0008406 98 62 1,000 0,07910046 0,12911513 ! respiratory burst GO:0045730 17 11 0,000 0,07952904 0,12972668 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,07952904 0,12963879 ! neuron fate specification GO:0048665 17 11 0,000 0,07952904 0,12955102 ! telencephalon cell migration GO:0022029 20 11 0,000 0,07952904 0,12946337 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,07952904 0,12937583 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,07952904 0,12928842 ! thyroid gland development GO:0030878 26 11 0,000 0,07952904 0,12920112 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07952904 0,12911394 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07952904 0,12902688 ! response to pain GO:0048265 24 11 0,000 0,07952904 0,12893993 ! T cell proliferation GO:0042098 26 11 0,000 0,07952904 0,1288531 ! bone resorption GO:0045453 16 11 0,000 0,07952904 0,12876639 ! ventral spinal cord development GO:0021517 21 11 0,000 0,07952904 0,1286798 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07952904 0,12859332 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07952904 0,12850696 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,07952904 0,12842071 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07952904 0,12833458 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,07952904 0,12824857 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07952904 0,12816267 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,07952904 0,12807688 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,07952904 0,12799121 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,07952904 0,12790565 ! UV protection GO:0009650 19 11 0,000 0,07952904 0,12782021 ! adult heart development GO:0007512 14 11 0,000 0,07952904 0,12773489 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07952904 0,12764967 ! temperature homeostasis GO:0001659 17 11 0,000 0,07952904 0,12756457 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07952904 0,12747959 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,07952904 0,12739471 ! regulation of organ growth GO:0046620 13 11 0,000 0,07952904 0,12730995 ! pigment granule localization GO:0051875 20 11 0,000 0,07952904 0,12722531 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,07952904 0,12714077 ! vasoconstriction GO:0042310 18 11 0,000 0,07952904 0,12705635 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07952904 0,12697204 ! embryonic axis specification GO:0000578 18 11 0,000 0,07952904 0,12688784 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07952904 0,12680375 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07952904 0,12671977 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07952904 0,12663591 ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07952904 0,12655216 ! zymogen activation GO:0031638 15 11 0,000 0,07952904 0,12646851 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07952904 0,12638498 ! neuroblast proliferation GO:0007405 24 11 0,000 0,07952904 0,12630156 ! nucleosome positioning GO:0016584 15 11 0,000 0,07952904 0,12621824 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07952904 0,12613504 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07952904 0,12605195 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07952904 0,12596897 ! acid secretion GO:0046717 18 11 0,000 0,07952904 0,12588609 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07952904 0,12580333 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07952904 0,12572067 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07952904 0,12563812 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,07952904 0,12555568 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,07952904 0,12547335 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,07952904 0,12539113 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07952904 0,12530901 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07952904 0,125227 ! germ cell migration GO:0008354 25 11 0,000 0,07952904 0,1251451 ! embryonic gut development GO:0048566 15 11 0,000 0,07952904 0,12506331 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07952904 0,12498162 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07952904 0,12490004 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07952904 0,12481856 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,07952904 0,1247372 ! defense response to fungus GO:0050832 13 11 0,000 0,07952904 0,12465593 ! developmental induction GO:0031128 19 11 0,000 0,07952904 0,12457478 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,07952904 0,12449373 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07952904 0,12441278 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,07952904 0,12433194 ! sequestering of metal ion GO:0051238 14 11 0,000 0,07952904 0,12425121 ! lamellipodium assembly GO:0030032 20 11 0,000 0,07952904 0,12417058 ! regulation of embryonic development GO:0045995 27 11 0,000 0,07952904 0,12409005 ! nucleus localization GO:0051647 19 11 0,000 0,07952904 0,12400963 ! regulation of synapse organization GO:0050807 17 11 0,000 0,07952904 0,12392931 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,08130383 0,12661296 ! detection of external stimulus GO:0009581 91 63 1,000 0,08130383 0,12653106 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,08130383 0,12644927 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,08352605 0,1298215 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,08352605 0,12973769 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 1,000 0,08352605 0,12965399 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,08576672 0,13304625 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,08576672 0,13296053 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,08643884 0,13391619 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,08643884 0,13383001 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,08643884 0,13374395 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,08643884 0,13365799 ! virus-host interaction GO:0019048 29 12 0,000 0,08643884 0,13357215 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,08643884 0,13348642 ! mating GO:0007618 17 12 0,000 0,08643884 0,13340079 ! protein complex disassembly GO:0043241 27 12 0,000 0,08643884 0,13331528 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,08643884 0,13322988 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,08643884 0,13314458 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,08643884 0,1330594 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,08643884 0,13297432 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,08643884 0,13288935 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,08643884 0,13280449 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,08643884 0,13271974 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,08643884 0,1326351 ! drug transport GO:0015893 16 12 0,000 0,08643884 0,13255057 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,08643884 0,13246614 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,08643884 0,13238182 ! polyamine metabolic process GO:0006595 17 12 0,000 0,08643884 0,13229761 ! mitotic spindle organization GO:0007052 21 12 0,000 0,08643884 0,1322135 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,08643884 0,1321295 ! forebrain cell migration GO:0021885 21 12 0,000 0,08643884 0,13204561 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,08643884 0,13196183 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,08643884 0,13187815 ! entry into host cell GO:0030260 32 12 0,000 0,08643884 0,13179457 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,08643884 0,13171111 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08643884 0,13162775 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,08643884 0,13154449 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,08643884 0,13146134 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,08643884 0,13137829 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08643884 0,13129535 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,08643884 0,13121252 ! protein homotetramerization GO:0051289 21 12 0,000 0,08643884 0,13112978 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,08643884 0,13104716 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,08643884 0,13096463 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08643884 0,13088221 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,08643884 0,1307999 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,08643884 0,13071769 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08643884 0,13063558 ! fucose catabolic process GO:0019317 22 12 0,000 0,08643884 0,13055357 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,08643884 0,13047167 ! histone methylation GO:0016571 26 12 0,000 0,08643884 0,13038987 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,08643884 0,13030817 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,08643884 0,13022657 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,08643884 0,13014508 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,08643884 0,13006369 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,08643884 0,1299824 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,08643884 0,12990121 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,08643884 0,12982012 ! response to cold GO:0009409 17 12 0,000 0,08643884 0,12973914 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,08643884 0,12965825 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,08643884 0,12957747 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,08802544 0,13187373 ! developmental maturation GO:0021700 116 66 1,000 0,08802544 0,13179167 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,09030181 0,13511578 ! activation of MAPK activity GO:0000187 115 67 1,000 0,09030181 0,1350318 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,09030181 0,13494793 ! activation of immune response GO:0002253 105 67 1,000 0,09030181 0,13486416 ! amino acid transport GO:0006865 125 68 1,000 0,09259545 0,13820388 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,09259545 0,1381182 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,09259545 0,13803263 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,09259545 0,13794716 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,09259545 0,13786179 ! cGMP metabolic process GO:0046068 18 13 0,000 0,09329699 0,13882039 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,09329699 0,13873459 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,09329699 0,1386489 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,09329699 0,13856331 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,09329699 0,13847783 ! lipid localization GO:0010876 28 13 0,000 0,09329699 0,13839246 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,09329699 0,13830719 ! organelle fusion GO:0048284 32 13 0,000 0,09329699 0,13822202 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,09329699 0,13813696 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,09329699 0,13805201 ! endocrine pancreas development GO:0031018 22 13 0,000 0,09329699 0,13796716 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,09329699 0,13788241 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,09329699 0,13779777 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,09329699 0,13771323 ! methionine metabolic process GO:0006555 27 13 0,000 0,09329699 0,13762879 ! plasma membrane organization GO:0007009 24 13 0,000 0,09329699 0,13754446 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,09329699 0,13746024 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,09329699 0,13737611 ! Golgi organization GO:0007030 24 13 0,000 0,09329699 0,13729209 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,09329699 0,13720817 ! cytokine metabolic process GO:0042107 22 13 0,000 0,09329699 0,13712435 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,09329699 0,13704064 ! exocrine system development GO:0035272 32 13 0,000 0,09329699 0,13695703 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,09329699 0,13687351 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,09329699 0,13679011 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,09329699 0,1367068 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,09329699 0,13662359 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,09329699 0,13654049 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,09329699 0,13645749 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,09329699 0,13637458 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,09329699 0,13629178 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,09329699 0,13620908 ! ribosome assembly GO:0042255 17 13 0,000 0,09329699 0,13612648 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,09329699 0,13604398 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,09329699 0,13596158 ! chromatin silencing GO:0006342 26 13 0,000 0,09329699 0,13587928 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,09329699 0,13579707 ! regulation of epidermis development GO:0045682 19 13 0,000 0,09329699 0,13571497 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,09329699 0,13563297 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,09329699 0,13555107 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,09329699 0,13546926 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,09329699 0,13538755 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,09329699 0,13530595 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,09329699 0,13522444 ! insulin secretion GO:0030073 23 13 0,000 0,09329699 0,13514302 ! actin filament polymerization GO:0030041 24 13 0,000 0,09329699 0,13506171 ! acrosome reaction GO:0007340 18 13 0,000 0,09329699 0,1349805 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,09490597 0,13722582 ! appendage morphogenesis GO:0035107 135 70 1,000 0,09723299 0,14050605 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,09957613 0,14380562 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,09957613 0,14371936 ! rRNA transcription GO:0009303 25 14 0,000 0,10010389 0,14439446 ! lactation GO:0007595 26 14 0,000 0,10010389 0,14430795 ! reproductive cellular process GO:0048610 20 14 0,000 0,10010389 0,14422153 ! tRNA modification GO:0006400 20 14 0,000 0,10010389 0,14413523 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,10010389 0,14404902 ! regulation of S phase GO:0033261 23 14 0,000 0,10010389 0,14396292 ! water transport GO:0006833 21 14 0,000 0,10010389 0,14387692 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,10010389 0,14379102 ! non-recombinational repair GO:0000726 25 14 0,000 0,10010389 0,14370523 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,10010389 0,14361954 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,10010389 0,14353395 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,10010389 0,14344846 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,10010389 0,14336307 ! palate development GO:0060021 31 14 0,000 0,10010389 0,14327779 ! regulated secretory pathway GO:0045055 23 14 0,000 0,10010389 0,14319261 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,10010389 0,14310752 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,10010389 0,14302254 ! arginine metabolic process GO:0006525 17 14 0,000 0,10010389 0,14293766 ! regulation of heart rate GO:0002027 24 14 0,000 0,10010389 0,14285288 ! organic alcohol transport GO:0015850 29 14 0,000 0,10010389 0,14276821 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,10010389 0,14268363 ! embryo implantation GO:0007566 30 14 0,000 0,10010389 0,14259915 ! neutral amino acid transport GO:0015804 26 14 0,000 0,10010389 0,14251477 ! L-amino acid transport GO:0015807 30 14 0,000 0,10010389 0,14243049 ! bone mineralization GO:0030282 17 14 0,000 0,10010389 0,14234631 ! stem cell development GO:0048864 43 14 0,000 0,10010389 0,14226223 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,10010389 0,14217825 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,10010389 0,14209437 ! cerebellum development GO:0021549 21 14 0,000 0,10010389 0,14201059 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,10010389 0,14192691 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,10010389 0,14184332 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,10010389 0,14175984 ! cofactor transport GO:0051181 26 14 0,000 0,10010389 0,14167645 ! NADP metabolic process GO:0006739 24 14 0,000 0,10010389 0,14159316 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,10010389 0,14150997 ! intestinal absorption GO:0050892 25 14 0,000 0,10010389 0,14142687 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,10010389 0,14134387 ! oxygen transport GO:0015671 21 14 0,000 0,10010389 0,14126098 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,10010389 0,14117817 ! regulation of axon extension GO:0030516 37 14 0,000 0,10010389 0,14109547 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,10010389 0,14101286 ! acute inflammatory response GO:0002526 113 72 1,000 0,10193503 0,1435083 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,10193503 0,14342438 ! learning or memory GO:0007611 147 73 1,000 0,10430932 0,14667926 ! axon guidance GO:0007411 139 73 1,000 0,10430932 0,14659359 ! fertilization GO:0009566 90 73 1,000 0,10430932 0,14650801 ! meiosis GO:0007126 121 74 1,000 0,10669863 0,1497765 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,10669863 0,14968916 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,10685991 0,14982806 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,10685991 0,1497408 ! superoxide anion generation GO:0042554 20 15 0,000 0,10685991 0,14965364 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,10685991 0,14956658 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,10685991 0,14947962 ! copper ion transport GO:0006825 20 15 0,000 0,10685991 0,14939277 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,10685991 0,14930601 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,10685991 0,14921936 ! sulfate transport GO:0008272 23 15 0,000 0,10685991 0,1491328 ! response to cAMP GO:0051591 22 15 0,000 0,10685991 0,14904635 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,10685991 0,14895999 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,10685991 0,14887374 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,10685991 0,14878759 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,10685991 0,14870153 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,10685991 0,14861558 ! response to hexose stimulus GO:0009746 22 15 0,000 0,10685991 0,14852972 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,10685991 0,14844397 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,10685991 0,14835831 ! pituitary gland development GO:0021983 29 15 0,000 0,10685991 0,14827275 ! vesicle coating GO:0006901 33 15 0,000 0,10685991 0,14818729 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,10685991 0,14810193 ! regulation of exocytosis GO:0017157 22 15 0,000 0,10685991 0,14801667 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,10685991 0,1479315 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,10685991 0,14784644 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,10685991 0,14776147 ! regulation of vasodilation GO:0042312 26 15 0,000 0,10685991 0,14767659 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,10685991 0,14759182 ! histone deacetylation GO:0016575 20 15 0,000 0,10685991 0,14750714 ! mRNA splice site selection GO:0006376 38 15 0,000 0,10685991 0,14742256 ! tissue regeneration GO:0042246 26 15 0,000 0,10685991 0,14733808 ! water homeostasis GO:0030104 27 15 0,000 0,10685991 0,14725369 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,10685991 0,14716941 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,10685991 0,14708521 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,10685991 0,14700112 ! dopamine metabolic process GO:0042417 35 15 0,000 0,10685991 0,14691711 ! heme biosynthetic process GO:0006783 29 15 0,000 0,10685991 0,14683321 ! cell killing GO:0001906 29 15 0,000 0,10685991 0,1467494 ! detection of bacterium GO:0016045 18 15 0,000 0,10685991 0,14666569 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,10685991 0,14658207 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,10685991 0,14649855 ! peptide hormone processing GO:0016486 23 15 0,000 0,10685991 0,14641512 ! rhythmic process GO:0048511 128 75 1,000 0,10910262 0,14940291 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,11152093 0,15262762 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,11356544 0,15533737 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,11356544 0,15524911 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,11356544 0,15516095 ! bone remodeling GO:0046849 27 16 0,000 0,11356544 0,15507289 ! filopodium assembly GO:0046847 32 16 0,000 0,11356544 0,15498493 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,11356544 0,15489707 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,11356544 0,15480931 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,11356544 0,15472165 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,11356544 0,15463409 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,11356544 0,15454663 ! startle response GO:0001964 28 16 0,000 0,11356544 0,15445926 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,11356544 0,154372 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,11356544 0,15428483 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,11356544 0,15419776 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,11356544 0,15411079 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,11356544 0,15402392 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,11356544 0,15393715 ! protein polyubiquitination GO:0000209 34 16 0,000 0,11356544 0,15385047 ! glutamate metabolic process GO:0006536 22 16 0,000 0,11356544 0,15376389 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,11356544 0,15367741 ! response to osmotic stress GO:0006970 25 16 0,000 0,11356544 0,15359103 ! lysosomal transport GO:0007041 26 16 0,000 0,11356544 0,15350474 ! fructose metabolic process GO:0006000 25 16 0,000 0,11356544 0,15341855 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,11356544 0,15333246 ! intermediate filament-based process GO:0045103 32 16 0,000 0,11356544 0,15324646 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,11356544 0,15316056 ! negative regulation of immune response GO:0050777 35 16 0,000 0,11356544 0,15307476 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,11356544 0,15298905 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,11356544 0,15290344 ! DNA replication initiation GO:0006270 27 16 0,000 0,11356544 0,15281792 ! neuron recognition GO:0008038 35 16 0,000 0,11356544 0,1527325 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,11356544 0,15264717 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,11356544 0,15256194 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,11356544 0,15247681 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,11356544 0,15239177 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,11356544 0,15230682 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,11356544 0,15222197 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,11356544 0,15213722 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,11356544 0,15205255 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,11356544 0,15196799 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,11356544 0,15188351 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,11395321 0,15231746 ! blood coagulation GO:0007596 146 78 1,000 0,11639912 0,15550043 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,11639912 0,15541414 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,11639912 0,15532794 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,11639912 0,15524184 ! protein oligomerization GO:0051259 139 78 1,000 0,11639912 0,15515583 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,11885831 0,15834613 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,11885831 0,1582585 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,12022084 0,15998414 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,12022084 0,15989571 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,12022084 0,15980737 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,12022084 0,15971912 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,12022084 0,15963098 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,12022084 0,15954293 ! endothelial cell migration GO:0043542 28 17 0,000 0,12022084 0,15945498 ! inositol metabolic process GO:0006020 28 17 0,000 0,12022084 0,15936713 ! gene silencing by RNA GO:0031047 36 17 0,000 0,12022084 0,15927937 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,12022084 0,15919171 ! glial cell development GO:0021782 27 17 0,000 0,12022084 0,15910414 ! limbic system development GO:0021761 36 17 0,000 0,12022084 0,15901668 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,12022084 0,1589293 ! adult walking behavior GO:0007628 33 17 0,000 0,12022084 0,15884203 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,12022084 0,15875485 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,12022084 0,15866776 ! myoblast differentiation GO:0045445 45 17 0,000 0,12022084 0,15858077 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,12022084 0,15849388 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,12022084 0,15840708 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,12022084 0,15832038 ! glycine metabolic process GO:0006544 28 17 0,000 0,12022084 0,15823377 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,12022084 0,15814726 ! NAD metabolic process GO:0019674 29 17 0,000 0,12022084 0,15806084 ! membrane budding GO:0006900 37 17 0,000 0,12022084 0,15797451 ! DNA integration GO:0015074 29 17 0,000 0,12022084 0,15788828 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,12022084 0,15780215 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,12022084 0,1577161 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,12022084 0,15763015 GO:0002712|regulation of B cell mediated immunity, ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,12022084 0,1575443 ! steroid catabolic process GO:0006706 31 17 0,000 0,12022084 0,15745854 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,12022084 0,15737287 ! gas transport GO:0015669 25 17 0,000 0,12022084 0,15728729 ! organic cation transport GO:0015695 31 17 0,000 0,12022084 0,15720181 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,12022084 0,15711642 ! microspike assembly GO:0030035 36 17 0,000 0,12022084 0,15703113 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,12022084 0,15694592 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,12133046 0,15830862 ! response to metal ion GO:0010038 140 80 1,000 0,12133046 0,15822282 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,12133046 0,15813711 ! protein import into nucleus GO:0006606 158 80 1,000 0,12133046 0,15805149 ! nuclear import GO:0051170 161 81 1,000 0,12381524 0,16120101 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,12631231 0,16436313 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,12631231 0,16427428 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,12631231 0,16418553 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,12682649 0,16476486 ! neuron maturation GO:0042551 42 18 0,000 0,12682649 0,16467595 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,12682649 0,16458712 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,12682649 0,1644984 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,12682649 0,16440977 ! memory GO:0007613 31 18 0,000 0,12682649 0,16432123 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,12682649 0,16423279 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,12682649 0,16414445 ! patterning of blood vessels GO:0001569 39 18 0,000 0,12682649 0,1640562 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,12682649 0,16396804 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,12682649 0,16387998 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,12682649 0,16379202 ! response to fungus GO:0009620 21 18 0,000 0,12682649 0,16370415 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,12682649 0,16361637 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,12682649 0,16352869 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,12682649 0,1634411 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,12682649 0,1633536 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,12682649 0,1632662 ! vitamin transport GO:0051180 27 18 0,000 0,12682649 0,16317889 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,12682649 0,16309168 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,12682649 0,16300456 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,12682649 0,16291753 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,12682649 0,16283059 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,12682649 0,16274375 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,12682649 0,162657 ! regulation of lyase activity GO:0051339 160 83 1,000 0,12882136 0,16512743 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,13134206 0,1682689 ! hemostasis GO:0007599 158 84 1,000 0,13134206 0,16817935 ! protein secretion GO:0009306 39 19 0,000 0,13338276 0,17070155 ! positive regulation of translation GO:0045727 30 19 0,000 0,13338276 0,1706108 ! negative regulation of defense response GO:0031348 25 19 0,000 0,13338276 0,17052015 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,13338276 0,17042959 ! skin development GO:0043588 36 19 0,000 0,13338276 0,17033913 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,13338276 0,17024876 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,13338276 0,17015849 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,13338276 0,17006832 ! bile acid metabolic process GO:0008206 29 19 0,000 0,13338276 0,16997824 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,13338276 0,16988826 ! cerebral cortex development GO:0021987 36 19 0,000 0,13338276 0,16979837 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,13338276 0,16970858 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,13338276 0,16961888 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,13338276 0,16952928 ! plasma membrane fusion GO:0045026 28 19 0,000 0,13338276 0,16943977 ! peptide cross-linking GO:0018149 37 19 0,000 0,13338276 0,16935035 ! protein export from nucleus GO:0006611 36 19 0,000 0,13338276 0,16926103 ! heart process GO:0003015 30 19 0,000 0,13338276 0,16917181 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,13338276 0,16908268 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,13338276 0,16899364 ! visual learning GO:0008542 36 19 0,000 0,13338276 0,16890469 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,13338276 0,16881584 ! cell-cell junction organization GO:0045216 35 19 0,000 0,13338276 0,16872709 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,13338276 0,16863842 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,13338276 0,16854985 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,13338276 0,16846137 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,13338276 0,16837299 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,13338276 0,1682847 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,13338276 0,1681965 ! cilium assembly GO:0042384 37 19 0,000 0,13338276 0,16810839 ! peptide hormone secretion GO:0030072 31 19 0,000 0,13338276 0,16802038 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,13387411 0,16855107 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,13387411 0,16846292 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,13641719 0,17157332 ! amine transport GO:0015837 155 86 1,000 0,13641719 0,17148367 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,13897099 0,17460272 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,13897099 0,17451159 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,13989002 0,17557401 ! positive regulation of ossification GO:0045778 47 20 0,000 0,13989002 0,17548247 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,13989002 0,17539103 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,13989002 0,17529968 ! cAMP metabolic process GO:0046058 36 20 0,000 0,13989002 0,17520843 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,13989002 0,17511727 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,13989002 0,1750262 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,13989002 0,17493523 ! retinoid metabolic process GO:0001523 32 20 0,000 0,13989002 0,17484436 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,13989002 0,17475357 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,13989002 0,17466289 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,13989002 0,17457229 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,13989002 0,1744818 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,13989002 0,17439139 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,13989002 0,17430108 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,13989002 0,17421086 ! body fluid secretion GO:0007589 31 20 0,000 0,13989002 0,17412074 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,13989002 0,17403071 ! peptide secretion GO:0002790 35 20 0,000 0,13989002 0,17394077 ! stem cell differentiation GO:0048863 53 20 0,000 0,13989002 0,17385092 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,13989002 0,17376117 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,13989002 0,17367151 ! sensory perception of pain GO:0019233 30 20 0,000 0,13989002 0,17358194 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,13989002 0,17349247 ! diencephalon development GO:0021536 34 20 0,000 0,13989002 0,17340308 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,13989002 0,17331379 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,13989002 0,17322459 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,13989002 0,17313549 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,13989002 0,17304647 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,13989002 0,17295755 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,13989002 0,17286871 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,13989002 0,17277997 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,13989002 0,17269132 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,13989002 0,17260276 ! actin filament-based movement GO:0030048 43 20 0,000 0,13989002 0,17251429 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,13989002 0,17242591 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,13989002 0,17233763 ! negative regulation of translation GO:0017148 29 20 0,000 0,13989002 0,17224943 ! regulation of cell killing GO:0031341 42 21 0,000 0,14634863 0,18010988 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,14634863 0,18001779 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,14634863 0,17992581 ! hormone secretion GO:0046879 38 21 0,000 0,14634863 0,17983392 ! glycerol metabolic process GO:0006071 34 21 0,000 0,14634863 0,17974212 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,14634863 0,17965041 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,14634863 0,1795588 ! axis specification GO:0009798 38 21 0,000 0,14634863 0,17946728 ! smooth muscle contraction GO:0006939 46 21 0,000 0,14634863 0,17937586 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,14634863 0,17928452 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,14634863 0,17919329 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,14634863 0,17910214 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,14634863 0,17901109 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,14634863 0,17892012 ! cytolysis GO:0019835 24 21 0,000 0,14634863 0,17882926 ! vasodilation GO:0042311 39 21 0,000 0,14634863 0,17873848 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,14634863 0,1786478 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,14634863 0,1785572 ! collagen fibril organization GO:0030199 59 21 0,000 0,14634863 0,1784667 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,14634863 0,17837629 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,14634863 0,17828598 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,14634863 0,17819575 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,14634863 0,17810562 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,14634863 0,17801557 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,14634863 0,17792562 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,14634863 0,17783576 ! collagen catabolic process GO:0030574 28 21 0,000 0,14634863 0,17774599 ! sperm-egg recognition GO:0035036 21 21 0,000 0,14634863 0,17765631 ! ossification GO:0001503 188 90 1,000 0,14669377 0,17798548 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,14669377 0,17789577 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,14669377 0,17780615 ! bone development GO:0060348 189 91 1,000 0,1492875 0,18085887 ! sterol metabolic process GO:0016125 152 91 1,000 0,1492875 0,18076785 ! response to protein stimulus GO:0051789 149 91 1,000 0,1492875 0,18067692 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,15275896 0,18478535 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,15275896 0,18469249 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,15275896 0,18459973 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,15275896 0,18450705 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,15275896 0,18441448 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,15275896 0,18432199 ! keratinization GO:0031424 28 22 0,000 0,15275896 0,1842296 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,15275896 0,1841373 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,15275896 0,18404509 ! sensory perception of taste GO:0050909 28 22 0,000 0,15275896 0,18395298 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,15275896 0,18386096 ! vacuolar transport GO:0007034 36 22 0,000 0,15275896 0,18376903 ! lysosome organization GO:0007040 41 22 0,000 0,15275896 0,18367719 ! central nervous system neuron development GO:0021954 46 22 0,000 0,15275896 0,18358544 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,15275896 0,18349379 ! fucose metabolic process GO:0006004 39 22 0,000 0,15275896 0,18340222 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,15275896 0,18331075 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,15275896 0,18321937 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,15275896 0,18312808 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,15275896 0,18303688 ! sarcomere organization GO:0045214 30 22 0,000 0,15275896 0,18294577 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,15275896 0,18285475 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,15275896 0,18276383 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,15275896 0,18267299 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,15275896 0,18258224 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,15450244 0,18457442 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,15450244 0,18448282 ! female pregnancy GO:0007565 164 94 1,000 0,15712309 0,18751892 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,15912136 0,18980961 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,15912136 0,18971556 ! gluconeogenesis GO:0006094 33 23 0,000 0,15912136 0,18962159 ! viral genome replication GO:0019079 41 23 0,000 0,15912136 0,18952772 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,15912136 0,18943394 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,15912136 0,18934025 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,15912136 0,18924666 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,15912136 0,18915316 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,15912136 0,18905975 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,15912136 0,18896643 ! visual behavior GO:0007632 42 23 0,000 0,15912136 0,18887321 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,15912136 0,18878007 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,15912136 0,18868703 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,15912136 0,18859408 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,15912136 0,18850123 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,15912136 0,18840846 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,15912136 0,18831579 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,15912136 0,1882232 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,15912136 0,18813071 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,15912136 0,18803831 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,15912136 0,18794599 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,15912136 0,18785377 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,15912136 0,18776164 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,15912136 0,1876696 ! fatty acid transport GO:0015908 44 23 0,000 0,15912136 0,18757765 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,15912136 0,18748579 ! hormone transport GO:0009914 40 23 0,000 0,15912136 0,18739402 ! cell-cell recognition GO:0009988 25 23 0,000 0,15912136 0,18730234 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,15912136 0,18721075 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,15912136 0,18711925 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,15912136 0,18702784 ! forebrain development GO:0030900 188 95 1,000 0,15975215 0,18767758 ! positive regulation of immune response GO:0050778 156 96 1,000 0,16238936 0,19068268 ! detection of stimulus GO:0051606 151 96 1,000 0,16238936 0,19058966 ! hormone metabolic process GO:0042445 157 97 1,000 0,16503445 0,19359965 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,16543619 0,19397635 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,16543619 0,19388187 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,16543619 0,19378748 ! vesicle docking GO:0048278 47 24 0,000 0,16543619 0,19369318 ! spinal cord development GO:0021510 47 24 0,000 0,16543619 0,19359897 ! vacuole organization GO:0007033 43 24 0,000 0,16543619 0,19350485 ! digestive system process GO:0022600 39 24 0,000 0,16543619 0,19341083 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,16543619 0,19331689 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,16543619 0,19322305 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,16543619 0,1931293 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,16543619 0,19303563 ! membrane depolarization GO:0051899 39 24 0,000 0,16543619 0,19294206 ! pallium development GO:0021543 49 24 0,000 0,16543619 0,19284858 ! pentose metabolic process GO:0019321 35 24 0,000 0,16543619 0,1927552 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,16543619 0,1926619 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,16543619 0,19256869 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,16543619 0,19247557 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,16543619 0,19238254 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,16543619 0,1922896 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,16543619 0,19219675 ! regulation of amine transport GO:0051952 40 24 0,000 0,16543619 0,192104 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,17034718 0,1977112 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,17170381 0,19918967 ! phototransduction GO:0007602 33 25 0,000 0,17170381 0,19909367 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,17170381 0,19899777 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,17170381 0,19890196 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,17170381 0,19880624 ! chromosome condensation GO:0030261 45 25 0,000 0,17170381 0,19871061 ! osteoblast differentiation GO:0001649 60 25 0,000 0,17170381 0,19861508 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,17170381 0,19851964 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,17170381 0,19842429 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,17170381 0,19832903 ! interaction with host GO:0051701 62 25 0,000 0,17170381 0,19823386 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,17170381 0,19813879 ! immunoglobulin production GO:0002377 55 25 0,000 0,17170381 0,1980438 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,17170381 0,19794891 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,17170381 0,1978541 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,17170381 0,19775939 ! telomere organization GO:0032200 43 25 0,000 0,17170381 0,19766477 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,17170381 0,19757024 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,17792456 0,20463026 ! embryonic pattern specification GO:0009880 44 26 0,000 0,17792456 0,20453249 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,17792456 0,20443481 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,17792456 0,20433723 ! initiation of viral infection GO:0019059 57 26 0,000 0,17792456 0,20423974 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,17792456 0,20414235 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,17792456 0,20404504 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,17792456 0,20394783 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,17792456 0,20385072 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,17792456 0,20375369 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,17792456 0,20365676 GO:0051297|centrosome organization, ! response to estradiol stimulus GO:0032355 40 26 0,000 0,17792456 0,20355992 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,17792456 0,20346317 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,17792456 0,20336651 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,17792456 0,20326994 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,17792456 0,20317347 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,17792456 0,20307709 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,17792456 0,2029808 ! blastocyst development GO:0001824 49 26 0,000 0,17792456 0,2028846 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,17792456 0,20278849 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,17792456 0,20269247 ! neuron fate commitment GO:0048663 48 27 0,000 0,1840988 0,20962694 ! iron ion transport GO:0006826 59 27 0,000 0,1840988 0,20952778 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1840988 0,20942871 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,1840988 0,20932974 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,1840988 0,20923086 ! fat cell differentiation GO:0045444 50 27 0,000 0,1840988 0,20913207 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1840988 0,20903338 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1840988 0,20893477 ! autophagy GO:0006914 41 27 0,000 0,1840988 0,20883627 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1840988 0,20873785 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1840988 0,20863953 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1840988 0,2085413 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1840988 0,20844316 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1840988 0,20834512 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,19022688 0,21517906 ! circadian rhythm GO:0007623 50 28 0,000 0,19022688 0,21507794 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,19022688 0,21497692 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,19022688 0,21487599 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,19022688 0,21477516 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,19022688 0,21467442 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,19022688 0,21457378 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,19022688 0,21447323 ! synaptogenesis GO:0007416 42 28 0,000 0,19022688 0,21437277 ! lipid oxidation GO:0034440 43 28 0,000 0,19022688 0,21427241 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,19022688 0,21417214 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,19022688 0,21407197 ! translational initiation GO:0006413 65 29 0,000 0,19630912 0,22081335 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,19630912 0,22071016 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,19630912 0,22060708 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,19630912 0,22050408 ! catechol metabolic process GO:0009712 54 29 0,000 0,19630912 0,22040119 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,19630912 0,22029839 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,19630912 0,22019569 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,19630912 0,22009308 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,19630912 0,21999057 ! cell fate determination GO:0001709 60 29 0,000 0,19630912 0,21988815 ! detection of light stimulus GO:0009583 38 29 0,000 0,19630912 0,21978583 ! phenol metabolic process GO:0018958 55 30 0,000 0,20234589 0,22643916 ! zinc ion transport GO:0006829 45 30 0,000 0,20234589 0,22633389 ! membrane docking GO:0022406 61 30 0,000 0,20234589 0,22622872 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,20234589 0,22612364 ! regulation of innate immune response GO:0045088 51 30 0,000 0,20234589 0,22601866 ! acute-phase response GO:0006953 49 30 0,000 0,20234589 0,22591378 ! myofibril assembly GO:0030239 47 30 0,000 0,20234589 0,225809 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,20234589 0,22570431 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,20234589 0,22559972 ! phospholipid transport GO:0015914 51 30 0,000 0,20234589 0,22549523 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,20234589 0,22539083 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,20234589 0,22528653 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,20234589 0,22518233 ! eye morphogenesis GO:0048592 60 30 0,000 0,20234589 0,22507823 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,2083375 0,23163588 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,2083375 0,23152888 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,2083375 0,23142199 GO:0009799|determination of symmetry, ! cholesterol homeostasis GO:0042632 53 31 0,000 0,2083375 0,2313152 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,2083375 0,2312085 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,2083375 0,23110191 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,2083375 0,23099541 ! peptide transport GO:0015833 55 31 0,000 0,2083375 0,23088901 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,2083375 0,23078271 ! natural killer cell activation GO:0030101 45 31 0,000 0,2083375 0,2306765 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,2083375 0,23057039 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,2083375 0,23046438 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,2083375 0,23035847 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,2083375 0,23025266 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,21428431 0,23671628 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,21428431 0,23660765 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,21428431 0,23649911 ! cholesterol transport GO:0030301 56 32 0,000 0,21428431 0,23639067 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,21428431 0,23628234 ! spliceosome assembly GO:0000245 67 32 0,000 0,21428431 0,2361741 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,21428431 0,23606596 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,21428431 0,23595792 ! muscle cell development GO:0055001 49 32 0,000 0,21428431 0,23584998 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,21428431 0,23574214 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,21428431 0,2356344 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,21428431 0,23552675 ! BMP signaling pathway GO:0030509 64 32 0,000 0,21428431 0,23541921 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,21428431 0,23531176 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,21428431 0,23520441 ! gene silencing GO:0016458 65 32 0,000 0,21428431 0,23509715 ! protein targeting to membrane GO:0006612 68 33 0,000 0,22018665 0,24146266 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,22018665 0,24135266 ! ceramide metabolic process GO:0006672 64 33 0,000 0,22018665 0,24124275 ! sterol transport GO:0015918 57 33 0,000 0,22018665 0,24113294 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,22018665 0,24102324 ! adult locomotory behavior GO:0008344 59 33 0,000 0,22018665 0,24091363 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,22018665 0,24080413 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,22604484 0,24709854 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,22604484 0,24698632 ! mismatch repair GO:0006298 46 34 0,000 0,22604484 0,24687421 ! spermatid development GO:0007286 63 34 0,000 0,22604484 0,2467622 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,22604484 0,24665029 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,22604484 0,24653848 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,22604484 0,24642677 ! negative regulation of secretion GO:0051048 63 35 0,000 0,23185922 0,25265094 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,23185922 0,25253657 ! telencephalon development GO:0021537 68 35 0,000 0,23185922 0,2524223 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,23185922 0,25230813 ! cytokine production GO:0001816 59 35 0,000 0,23185922 0,25219407 ! vesicle localization GO:0051648 64 35 0,000 0,23185922 0,25208011 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,2376301 0,25823759 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,2376301 0,25812101 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,2376301 0,25800453 ! regulation of proteolysis GO:0030162 72 36 0,000 0,2376301 0,25788815 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,2376301 0,25777188 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,2376301 0,25765571 ! aerobic respiration GO:0009060 55 36 0,000 0,2376301 0,25753965 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,2376301 0,2574237 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,2376301 0,25730784 ! RNA export from nucleus GO:0006405 56 37 0,000 0,24335782 0,26339133 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,24335782 0,2632729 ! meiosis I GO:0007127 65 37 0,000 0,24335782 0,26315457 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,24335782 0,26303635 ! sister chromatid segregation GO:0000819 58 37 0,000 0,24335782 0,26291824 ! actomyosin structure organization GO:0031032 62 37 0,000 0,24335782 0,26280024 ! organic anion transport GO:0015711 68 37 0,000 0,24335782 0,26268234 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,24335782 0,26256454 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,24335782 0,26244685 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,24335782 0,26232927 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,2490427 0,2683371 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,2490427 0,26821698 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,2490427 0,26809698 ! lipid homeostasis GO:0055088 67 38 0,000 0,2490427 0,26797708 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,2490427 0,26785728 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,2490427 0,2677376 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,2490427 0,26761802 ! mRNA catabolic process GO:0006402 71 39 0,000 0,25468506 0,27355904 ! learning GO:0007612 77 39 0,000 0,25468506 0,27343697 ! ion transmembrane transport GO:0034220 66 39 0,000 0,25468506 0,27331501 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,25468506 0,27319315 ! RNA modification GO:0009451 57 39 0,000 0,25468506 0,27307141 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,2602852 0,27895153 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,2602852 0,27882734 ! feeding behavior GO:0007631 59 40 0,000 0,2602852 0,27870325 ! cytokinesis GO:0000910 72 40 0,000 0,2602852 0,27857927 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,26584345 0,28440167 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,26584345 0,28427527 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,26584345 0,28414898 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,26584345 0,2840228 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,26584345 0,28389674 ! polyol metabolic process GO:0019751 66 41 0,000 0,26584345 0,28377078 ! regulation of tube size GO:0035150 71 42 0,000 0,27136012 0,28953102 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,27136012 0,28940269 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,27136012 0,28927446 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,27136012 0,28914635 ! regulation of protein secretion GO:0050708 71 42 0,000 0,27136012 0,28901835 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,27683552 0,29471959 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,27683552 0,29458924 ! glucose transport GO:0015758 65 43 0,000 0,27683552 0,294459 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,27683552 0,29432889 ! striated muscle contraction GO:0006941 77 43 0,000 0,27683552 0,29419888 ! phagocytosis GO:0006909 90 43 0,000 0,27683552 0,29406899 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,27683552 0,29393922 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,28226996 0,2995772 ! hexose transport GO:0008645 67 44 0,000 0,28226996 0,29944511 GO:0015749|monosaccharide transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,28226996 0,29931314 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,28766373 0,30489821 ! glycolysis GO:0006096 65 45 0,000 0,28766373 0,30476395 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,28766373 0,30462981 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,28766373 0,30449579 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,28766373 0,30436189 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,28766373 0,3042281 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,28766373 0,30409444 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,29301715 0,30961759 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,29301715 0,30948168 ! response to calcium ion GO:0051592 81 47 0,000 0,29833051 0,31495534 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,29833051 0,3148172 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,29833051 0,31467918 ! JNK cascade GO:0007254 91 47 0,000 0,29833051 0,31454129 ! protein homooligomerization GO:0051260 76 47 0,000 0,29833051 0,31440351 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,30360412 0,31982115 ! Notch signaling pathway GO:0007219 96 48 0,000 0,30360412 0,31968118 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,30360412 0,31954134 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,30360412 0,31940162 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,30883826 0,32476611 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,30883826 0,32462423 ! regulation of ion transport GO:0043269 77 49 0,000 0,30883826 0,32448247 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,30883826 0,32434084 ! endocrine system development GO:0035270 104 49 0,000 0,30883826 0,32419933 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,30883826 0,32405794 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,30883826 0,32391668 ! neuromuscular process GO:0050905 99 50 0,000 0,31403324 0,32922177 ! viral infectious cycle GO:0019058 99 51 0,000 0,31918934 0,33448151 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,31918934 0,33433589 ! excretion GO:0007588 83 51 0,000 0,31918934 0,3341904 ! membrane fusion GO:0006944 110 52 0,000 0,32430685 0,33940074 ! amino acid activation GO:0043038 92 52 0,000 0,32430685 0,33925317 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,32938607 0,34441673 ! RNA catabolic process GO:0006401 93 53 0,000 0,32938607 0,34426711 ! regulation of translational initiation GO:0006446 82 53 0,000 0,32938607 0,34411762 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,32938607 0,34396827 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,32938607 0,34381904 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,32938607 0,34366994 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,33442727 0,34877851 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,33442727 0,34862739 ! cell recognition GO:0008037 85 54 0,000 0,33442727 0,34847641 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,33442727 0,34832555 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,33442727 0,34817483 ! chloride transport GO:0006821 90 55 0,000 0,33943075 0,35323113 ! glucose catabolic process GO:0006007 82 55 0,000 0,33943075 0,35307842 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,33943075 0,35292583 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,33943075 0,35277338 ! nuclear export GO:0051168 97 55 0,000 0,33943075 0,35262106 ! regulation of actin filament length GO:0030832 105 56 0,000 0,34439677 0,35762565 ! sensory perception of smell GO:0007608 80 56 0,000 0,34439677 0,35747137 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,34439677 0,35731722 ! proton transport GO:0015992 94 56 0,000 0,34439677 0,35716321 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,34439677 0,35700932 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,34932563 0,36196273 ! hydrogen transport GO:0006818 97 58 0,000 0,35421759 0,36687367 ! regulation of endocytosis GO:0030100 91 58 0,000 0,35421759 0,3667158 ! adult behavior GO:0030534 99 58 0,000 0,35421759 0,36655808 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,35421759 0,36640048 ! positive regulation of secretion GO:0051047 95 59 0,000 0,35907294 0,37126321 ! regulation of cellular component size GO:0032535 109 59 0,000 0,35907294 0,37110373 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,35907294 0,37094439 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,35907294 0,37078519 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,36389194 0,37560017 ! camera-type eye development GO:0043010 116 60 0,000 0,36389194 0,37543911 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,36867486 0,38021077 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,36867486 0,38004787 ! tRNA processing GO:0008033 89 61 0,000 0,36867486 0,37988511 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,36867486 0,37972248 ! viral reproductive process GO:0022415 126 62 0,000 0,37342199 0,38444728 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,37342199 0,38428285 ! regulation of mitosis GO:0007088 105 63 0,000 0,37813357 0,3889651 GO:0051783|regulation of nuclear division, ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,37813357 0,38879887 ! cell redox homeostasis GO:0045454 102 64 0,000 0,38280988 0,39343894 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,38745118 0,39803908 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,38745118 0,3978692 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,38745118 0,39769946 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,39662979 0,40694724 ! chromosome segregation GO:0007059 113 67 0,000 0,39662979 0,40677377 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,39662979 0,40660045 ! hexose catabolic process GO:0019320 104 67 0,000 0,39662979 0,40642729 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,39662979 0,40625426 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,40116761 0,41072735 ! viral reproduction GO:0016032 134 68 0,000 0,40116761 0,41055265 ! regulation of lipase activity GO:0060191 130 68 0,000 0,40116761 0,41037809 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,40567146 0,41480898 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,40567146 0,41463277 ! antigen processing and presentation GO:0019882 104 69 0,000 0,40567146 0,4144567 ! amine catabolic process GO:0009310 117 71 0,000 0,41457823 0,42337658 ! regulation of immune effector process GO:0002697 137 71 0,000 0,41457823 0,42319696 ! carbohydrate transport GO:0008643 110 72 0,000 0,41898166 0,42751055 ! regulation of blood pressure GO:0008217 125 73 0,000 0,42335211 0,43178685 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,42335211 0,43160389 ! transition metal ion transport GO:0000041 126 74 0,000 0,42768983 0,43584147 ! neurotransmitter transport GO:0006836 123 74 0,000 0,42768983 0,43565695 ! exocytosis GO:0006887 133 74 0,000 0,42768983 0,43547259 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,42768983 0,43528838 ! eye development GO:0001654 143 74 0,000 0,42768983 0,43510432 ! organelle localization GO:0051640 136 74 0,000 0,42768983 0,43492042 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,43199506 0,43911285 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,43199506 0,43892741 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,43626805 0,44308186 ! defense response to bacterium GO:0042742 89 76 0,000 0,43626805 0,4428949 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,43626805 0,44270811 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,44050903 0,44682324 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,44050903 0,44663495 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,44889594 0,45494677 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,44889594 0,45475522 ! muscle cell differentiation GO:0042692 159 80 0,000 0,45304234 0,45876257 ! inorganic anion transport GO:0015698 138 80 0,000 0,45304234 0,45856957 ! digestion GO:0007586 112 81 0,000 0,45715768 0,46254053 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,45715768 0,4623461 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,46931965 0,47444667 ! response to unfolded protein GO:0006986 131 85 0,000 0,47331305 0,47828273 ! nucleosome assembly GO:0006334 122 85 0,000 0,47331305 0,47808194 ! amine biosynthetic process GO:0009309 138 86 0,000 0,47727653 0,48188306 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,47727653 0,48168092 ! chromatin assembly GO:0031497 124 86 0,000 0,47727653 0,48147896 ! alcohol catabolic process GO:0046164 130 86 0,000 0,47727653 0,48127717 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,48121031 0,48504064 ! cellular respiration GO:0045333 135 88 0,000 0,48511462 0,48877127 ! regulation of neurological system process GO:0031644 148 88 0,000 0,48511462 0,48856667 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,48511462 0,48836225 ! cellular defense response GO:0006968 114 89 0,000 0,48898968 0,49205737 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,4928357 0,49572019 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,4966529 0,49935098 ! nucleosome organization GO:0034728 138 92 0,000 0,5004415 0,50294998 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,5004415 0,50273998 ! vitamin metabolic process GO:0006766 139 92 0,000 0,5004415 0,50253016 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,50420171 0,50609483 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,50793374 0,50962826 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,5116378 0,5131307 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,5153141 0,51660238 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,5153141 0,51638722 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,51896284 0,51982706 ! protein ubiquitination GO:0016567 217 97 0,000 0,51896284 0,51961074 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,52258424 0,523019 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,52258424 0,52280153 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,5261785 0,5261785