pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6903-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cell growth GO:0001558 97 96 6,000 5,84E-08 1,076E-04 ! chromosome segregation GO:0007059 38 38 4,000 2,892E-07 2,665E-04 ! amyloid precursor protein catabolic process GO:0042987 5 5 2,000 5,363E-07 3,295E-04 ! amyloid precursor protein metabolic process GO:0042982 7 7 2,000 1,867E-06 8,604E-04 ! membrane protein ectodomain proteolysis GO:0006509 7 7 2,000 1,867E-06 6,883E-04 GO:0033619|membrane protein proteolysis, ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 2,000 2,98E-06 9,153E-04 ! glycoprotein catabolic process GO:0006516 13 12 2,000 1,158E-05 3,05E-03 ! G1 phase GO:0051318 13 12 2,000 1,158E-05 2,669E-03 ! forebrain development GO:0030900 43 42 3,000 1,902E-05 3,895E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 2,377E-05 4,381E-03 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 2,000 2,377E-05 3,983E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 2,000 2,918E-05 4,482E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 3,675E-05 5,21E-03 ! Notch signaling pathway GO:0007219 22 21 2,000 6,84E-05 9,005E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 6,84E-05 8,404E-03 ! neuron migration GO:0001764 22 22 2,000 7,9E-05 9,099E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 1,033E-04 0,01119695 ! response to insulin stimulus GO:0032868 28 26 2,000 1,32E-04 0,01351343 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 1,367E-04 0,01325537 ! endocrine pancreas development GO:0031018 5 5 1,000 1,473E-04 0,01356933 ! central nervous system neuron axonogenesis GO:0021955 6 5 1,000 1,473E-04 0,01292317 GO:0021952|central nervous system projection neuron axonogenesis, ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 1,473E-04 0,01233575 ! DNA methylation GO:0006306 5 5 1,000 1,473E-04 0,01179942 GO:0006305|DNA alkylation, ! T cell lineage commitment GO:0002360 5 5 1,000 1,473E-04 0,01130777 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,473E-04 0,01085546 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 1,473E-04 0,01043795 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 2,094E-04 0,01429186 ! axon extension GO:0048675 7 6 1,000 2,203E-04 0,01450336 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,203E-04 0,01400324 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of lipid kinase activity GO:0043550 6 6 1,000 2,203E-04 0,01353647 ! ER overload response GO:0006983 6 6 1,000 2,203E-04 0,01309981 ! focal adhesion formation GO:0048041 7 6 1,000 2,203E-04 0,01269044 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,203E-04 0,01230588 GO:0070667|negative regulation of mast cell proliferation, ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,203E-04 0,01194394 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,203E-04 0,01160269 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,203E-04 0,01128039 ! nitric oxide metabolic process GO:0046209 6 6 1,000 2,203E-04 0,01097551 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 1,000 2,203E-04 0,01068668 ! regulation of DNA replication GO:0006275 32 31 2,000 2,252E-04 0,01064259 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 2,252E-04 0,01037653 ! negative regulation of cell growth GO:0030308 32 32 2,000 2,479E-04 0,0111415 ! protein maturation by peptide bond cleavage GO:0051605 32 32 2,000 2,479E-04 0,01087623 ! negative regulation of cell size GO:0045792 33 33 2,000 2,719E-04 0,01165509 ! regulation of angiogenesis GO:0045765 35 34 2,000 2,975E-04 0,01245984 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 2,975E-04 0,01218296 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 3,077E-04 0,01232946 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 3,077E-04 0,01206713 ! regulation of intracellular pH GO:0051453 7 7 1,000 3,077E-04 0,01181573 ! response to gamma radiation GO:0010332 8 7 1,000 3,077E-04 0,01157459 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 3,077E-04 0,0113431 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 3,077E-04 0,01112069 ! negative regulation of T cell activation GO:0050868 7 7 1,000 3,077E-04 0,01090683 ! brain development GO:0007420 91 90 3,000 3,818E-04 0,01327637 ! response to drug GO:0042493 37 37 2,000 3,832E-04 0,01307956 ! negative regulation of growth GO:0045926 37 37 2,000 3,832E-04 0,01284175 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 4,093E-04 0,013471 ! pancreas development GO:0031016 8 8 1,000 4,093E-04 0,01323467 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 4,093E-04 0,01300648 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 4,15E-04 0,01296327 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 4,835E-04 0,01485129 ! cell cycle checkpoint GO:0000075 42 41 2,000 5,203E-04 0,01571992 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 5,25E-04 0,01560588 ! RNA polyadenylation GO:0043631 9 9 1,000 5,25E-04 0,01535817 GO:0006378|mRNA polyadenylation, ! central nervous system neuron development GO:0021954 10 9 1,000 5,25E-04 0,0151182 ! regulation of cellular pH GO:0030641 9 9 1,000 5,25E-04 0,01488561 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 6,547E-04 0,01828074 ! plasma membrane organization GO:0007009 10 10 1,000 6,547E-04 0,0180079 ! cell-substrate junction assembly GO:0007044 11 10 1,000 6,547E-04 0,01774307 ! central nervous system neuron differentiation GO:0021953 11 10 1,000 6,547E-04 0,01748593 ! neuromuscular junction development GO:0007528 10 10 1,000 6,547E-04 0,01723613 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 6,547E-04 0,01699337 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 6,547E-04 0,01675735 ! mRNA 3'-end processing GO:0031124 10 10 1,000 6,547E-04 0,01652779 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 6,854E-04 0,01706993 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 6,854E-04 0,01684233 ! protein processing GO:0016485 45 45 2,000 6,854E-04 0,01662073 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 7,313E-04 0,01750358 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 7,982E-04 0,01885998 ! dendrite development GO:0016358 11 11 1,000 7,982E-04 0,01862125 ! regulation of viral genome replication GO:0045069 11 11 1,000 7,982E-04 0,01838848 ! cellular response to starvation GO:0009267 11 11 1,000 7,982E-04 0,01816147 ! apoptotic nuclear changes GO:0030262 11 11 1,000 7,982E-04 0,01793999 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 7,982E-04 0,01772384 ! G1/S transition checkpoint GO:0031575 12 11 1,000 7,982E-04 0,01751284 ! RNA 3'-end processing GO:0031123 11 11 1,000 7,982E-04 0,01730681 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 7,982E-04 0,01710557 ! cell cycle arrest GO:0007050 49 49 2,000 8,806E-04 0,01865543 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 9,344E-04 0,01956947 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 9,555E-04 0,01978679 ! xenobiotic metabolic process GO:0006805 12 12 1,000 9,555E-04 0,01956694 ! regulation of chromosome organization GO:0033044 12 12 1,000 9,555E-04 0,01935192 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 9,555E-04 0,01914157 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 9,555E-04 0,01893575 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 9,902E-04 0,01941458 GO:0051325|interphase, ! protein maturation GO:0051604 51 51 2,000 9,902E-04 0,01921022 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 1,127E-03 0,02162685 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,127E-03 0,02140389 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,127E-03 0,02118548 ! actin filament bundle formation GO:0051017 13 13 1,000 1,127E-03 0,02097149 ! cell aging GO:0007569 13 13 1,000 1,127E-03 0,02076177 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,127E-03 0,02055621 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 1,127E-03 0,02035468 ! regulation of viral reproduction GO:0050792 13 13 1,000 1,127E-03 0,02015706 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,127E-03 0,01996324 ! protein tetramerization GO:0051262 13 13 1,000 1,127E-03 0,01977312 ! extracellular structure organization GO:0043062 56 56 2,000 1,301E-03 0,02261961 ! protein amino acid acylation GO:0043543 14 14 1,000 1,311E-03 0,02258271 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 1,311E-03 0,02237361 ! base-excision repair GO:0006284 14 14 1,000 1,311E-03 0,02216835 ! DNA modification GO:0006304 14 14 1,000 1,311E-03 0,02196682 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,509E-03 0,02505726 ! striated muscle cell differentiation GO:0051146 16 15 1,000 1,509E-03 0,02483354 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,509E-03 0,02461377 ! chromosome condensation GO:0030261 15 15 1,000 1,509E-03 0,02439786 ! response to starvation GO:0042594 15 15 1,000 1,509E-03 0,02418571 ! response to ionizing radiation GO:0010212 16 15 1,000 1,509E-03 0,02397721 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,509E-03 0,02377228 ! positive regulation of mitosis GO:0045840 16 16 1,000 1,721E-03 0,02687297 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,721E-03 0,02664714 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 1,721E-03 0,02642508 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,721E-03 0,02620669 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 1,721E-03 0,02599188 ! axonogenesis GO:0007409 66 62 2,000 1,747E-03 0,02618237 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,945E-03 0,02891231 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,945E-03 0,02868101 ! myelination GO:0042552 17 17 1,000 1,945E-03 0,02845339 ! glucose transport GO:0015758 17 17 1,000 1,945E-03 0,02822934 ! cell junction assembly GO:0034329 18 17 1,000 1,945E-03 0,0280088 ! response to toxin GO:0009636 18 17 1,000 1,945E-03 0,02779168 ! negative regulation of cell development GO:0010721 18 17 1,000 1,945E-03 0,0275779 GO:0050768|negative regulation of neurogenesis, ! meiosis I GO:0007127 18 18 1,000 2,183E-03 0,03071392 ! hexose transport GO:0008645 18 18 1,000 2,183E-03 0,03048124 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,183E-03 0,03025205 ! B cell differentiation GO:0030183 18 18 1,000 2,183E-03 0,03002629 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,183E-03 0,02980387 ! ensheathment of neurons GO:0007272 18 18 1,000 2,183E-03 0,02958473 GO:0008366|axon ensheathment, ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 2,185E-03 0,02938894 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 2,185E-03 0,02917598 ! regulation of cell size GO:0008361 68 68 2,000 2,28E-03 0,03022399 ! DNA damage checkpoint GO:0000077 19 19 1,000 2,434E-03 0,03204297 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,434E-03 0,03181572 ! regulation of pH GO:0006885 19 19 1,000 2,434E-03 0,03159166 ! cellular response to oxidative stress GO:0034599 19 19 1,000 2,434E-03 0,03137074 ! peripheral nervous system development GO:0007422 19 19 1,000 2,434E-03 0,03115289 ! cell part morphogenesis GO:0032990 75 70 2,000 2,477E-03 0,03148184 ! wound healing GO:0042060 74 70 2,000 2,477E-03 0,03126621 ! muscle tissue development GO:0060537 72 70 2,000 2,477E-03 0,03105352 ! nucleus organization GO:0006997 20 20 1,000 2,698E-03 0,03359746 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,698E-03 0,03337198 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 2,975E-03 0,03655045 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,975E-03 0,03630839 ! mammary gland development GO:0030879 23 21 1,000 2,975E-03 0,03606952 ! protein amino acid lipidation GO:0006497 21 21 1,000 2,975E-03 0,03583378 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,975E-03 0,03560109 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,975E-03 0,0353714 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,975E-03 0,03514466 ! response to oxidative stress GO:0006979 76 75 2,000 3,016E-03 0,03540158 ! sister chromatid segregation GO:0000819 22 22 1,000 3,264E-03 0,03807763 ! cell junction organization GO:0034330 23 22 1,000 3,264E-03 0,03783815 ! spindle organization GO:0007051 22 22 1,000 3,264E-03 0,03760166 ! erythrocyte differentiation GO:0030218 23 22 1,000 3,264E-03 0,03736811 ! biopolymer methylation GO:0043414 22 22 1,000 3,264E-03 0,03713744 GO:0032259|methylation, ! cytokinesis GO:0000910 23 22 1,000 3,264E-03 0,0369096 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 3,567E-03 0,04008134 ! endocrine system development GO:0035270 23 23 1,000 3,567E-03 0,03983842 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 3,567E-03 0,03959843 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 3,567E-03 0,03936131 ! neuron projection development GO:0031175 85 80 2,000 3,622E-03 0,03973244 ! mitochondrial transport GO:0006839 24 24 1,000 3,882E-03 0,04232906 ! regulation of action potential GO:0001508 24 24 1,000 3,882E-03 0,04208006 ! T cell differentiation GO:0030217 24 24 1,000 3,882E-03 0,04183398 ! erythrocyte homeostasis GO:0034101 25 24 1,000 3,882E-03 0,04159076 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 4,209E-03 0,0448376 ! endosome transport GO:0016197 25 25 1,000 4,209E-03 0,04457991 ! regulation of T cell proliferation GO:0042129 25 25 1,000 4,209E-03 0,04432517 ! negative regulation of immune system process GO:0002683 25 25 1,000 4,209E-03 0,04407332 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 4,298E-03 0,04474911 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 4,441E-03 0,04598603 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 4,549E-03 0,04683264 ! regulation of T cell differentiation GO:0045580 26 26 1,000 4,549E-03 0,04657246 ! double-strand break repair GO:0006302 27 26 1,000 4,549E-03 0,04631515 ! synapse organization GO:0050808 26 26 1,000 4,549E-03 0,04606067 ! activation of caspase activity GO:0006919 27 27 1,000 4,901E-03 0,04935438 ! mesenchymal cell development GO:0014031 29 27 1,000 4,901E-03 0,04908615 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! negative regulation of cell cycle GO:0045786 92 91 2,000 5,204E-03 0,05184328 ! DNA replication GO:0006260 91 91 2,000 5,204E-03 0,05156455 ! carbohydrate transport GO:0008643 28 28 1,000 5,265E-03 0,05188854 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 5,265E-03 0,05161254 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 5,265E-03 0,05133945 ! positive regulation of cell cycle GO:0045787 29 29 1,000 5,641E-03 0,05471992 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 5,641E-03 0,05443343 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 5,641E-03 0,05414992 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 5,641E-03 0,05386935 ! response to UV GO:0009411 29 29 1,000 5,641E-03 0,05359168 ! response to reactive oxygen species GO:0000302 31 30 1,000 6,03E-03 0,05698751 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 6,03E-03 0,05669676 GO:0043280|positive regulation of caspase activity, ! establishment of organelle localization GO:0051656 31 30 1,000 6,03E-03 0,05640896 ! endocytosis GO:0006897 99 98 2,000 6,398E-03 0,05954909 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 2,000 6,398E-03 0,05924984 ! skeletal muscle fiber development GO:0048741 31 31 1,000 6,43E-03 0,05925162 ! B cell activation GO:0042113 31 31 1,000 6,43E-03 0,05895683 ! lipoprotein metabolic process GO:0042157 31 31 1,000 6,43E-03 0,05866497 ! aging GO:0007568 32 31 1,000 6,43E-03 0,05837598 ! extracellular matrix organization GO:0030198 31 31 1,000 6,43E-03 0,05808982 ! response to hormone stimulus GO:0009725 102 100 2,000 6,766E-03 0,06082986 ! muscle organ development GO:0007517 102 100 2,000 6,766E-03 0,06053457 ! hemopoiesis GO:0030097 104 100 2,000 6,766E-03 0,06024214 ! muscle fiber development GO:0048747 32 32 1,000 6,842E-03 0,06062448 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 6,842E-03 0,06033441 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 7,266E-03 0,06376714 ! muscle cell differentiation GO:0042692 35 34 1,000 7,701E-03 0,06726909 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 7,701E-03 0,06695178 ! regulation of mitosis GO:0007088 37 36 1,000 8,607E-03 0,07447362 GO:0051783|regulation of nuclear division, ! positive regulation of organelle organization GO:0010638 36 36 1,000 8,607E-03 0,07412561 ! coagulation GO:0050817 39 36 1,000 8,607E-03 0,07378084 GO:0007596|blood coagulation, ! meiosis GO:0007126 37 37 1,000 9,077E-03 0,07744894 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 9,077E-03 0,07709203 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 9,077E-03 0,0767384 ! negative regulation of kinase activity GO:0033673 38 38 1,000 9,558E-03 0,08043775 ! cell-matrix adhesion GO:0007160 39 38 1,000 9,558E-03 0,08007213 ! meiotic cell cycle GO:0051321 38 38 1,000 9,558E-03 0,07970981 ! axon guidance GO:0007411 39 38 1,000 9,558E-03 0,07935075 ! hemostasis GO:0007599 42 39 1,000 0,01005068 0,0830646 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01005068 0,08269378 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01005068 0,08232625 ! protein oligomerization GO:0051259 39 39 1,000 0,01005068 0,08196197 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,01055422 0,08568909 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,01055422 0,08531326 ! organelle localization GO:0051640 41 40 1,000 0,01055422 0,08494071 ! regulation of caspase activity GO:0043281 41 41 1,000 0,01106878 0,0886946 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,01159427 0,09250323 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,01159427 0,09210451 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,01159427 0,09170921 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,01213062 0,09554158 ! mitochondrion organization GO:0007005 44 43 1,000 0,01213062 0,09513502 ! protein import into nucleus GO:0006606 44 44 1,000 0,01267773 0,09900444 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,01267773 0,0985867 ! nuclear import GO:0051170 45 45 1,000 0,01323551 0,10249177 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01380388 0,10644583 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01380388 0,10600231 ! actin filament organization GO:0007015 50 48 1,000 0,01497206 0,11449587 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,01497206 0,11402274 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01497206 0,11355351 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01557169 0,11761734 ! gland development GO:0048732 51 49 1,000 0,01557169 0,11713727 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01557169 0,1166611 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,01557169 0,11618879 ! T cell activation GO:0042110 51 50 1,000 0,01618158 0,12025263 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,01618158 0,11976969 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01618158 0,11929061 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01680164 0,12336819 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,01743178 0,12748717 ! cell fate commitment GO:0045165 52 52 1,000 0,01743178 0,12698326 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,01743178 0,12648333 ! response to light stimulus GO:0009416 53 52 1,000 0,01743178 0,12598732 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01807192 0,13010372 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,01938189 0,13899156 ! in utero embryonic development GO:0001701 55 55 1,000 0,01938189 0,13845283 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,01938189 0,13791826 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,01938189 0,13738781 ! rRNA transcription GO:0009303 5 5 0,000 0,0194743 0,13751395 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0194743 0,13698909 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0194743 0,13646822 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0194743 0,13595129 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0194743 0,13543827 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0194743 0,1349291 ! reproductive cellular process GO:0048610 5 5 0,000 0,0194743 0,13442375 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,0194743 0,13392217 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0194743 0,13342431 ! prostate gland development GO:0030850 5 5 0,000 0,0194743 0,13293015 ! metencephalon development GO:0022037 5 5 0,000 0,0194743 0,13243963 ! water transport GO:0006833 5 5 0,000 0,0194743 0,13195272 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0194743 0,13146938 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0194743 0,13098956 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0194743 0,13051324 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0194743 0,13004036 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0194743 0,12957091 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0194743 0,12910482 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0194743 0,12864208 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0194743 0,12818265 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0194743 0,12772648 ! filopodium assembly GO:0046847 7 5 0,000 0,0194743 0,12727355 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0194743 0,12682382 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0194743 0,12637726 ! GTP metabolic process GO:0046039 5 5 0,000 0,0194743 0,12593383 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0194743 0,1254935 ! mRNA stabilization GO:0048255 5 5 0,000 0,0194743 0,12505624 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0194743 0,12462202 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0194743 0,1241908 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0194743 0,12376255 ! social behavior GO:0035176 5 5 0,000 0,0194743 0,12333725 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0194743 0,12291487 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0194743 0,12249536 ! memory GO:0007613 5 5 0,000 0,0194743 0,12207871 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0194743 0,12166488 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0194743 0,12125385 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0194743 0,12084559 ! response to lipid GO:0033993 5 5 0,000 0,0194743 0,12044007 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0194743 0,12003726 ! hippocampus development GO:0021766 6 5 0,000 0,0194743 0,11963714 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0194743 0,11923967 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0194743 0,11884484 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0194743 0,11845261 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0194743 0,11806296 ! heart looping GO:0001947 5 5 0,000 0,0194743 0,11767587 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0194743 0,11729131 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0194743 0,11690925 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0194743 0,11652968 ! pH reduction GO:0045851 5 5 0,000 0,0194743 0,11615256 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0194743 0,11577787 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0194743 0,1154056 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0194743 0,11503571 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0194743 0,11466818 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0194743 0,114303 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0194743 0,11394013 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0194743 0,11357956 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0194743 0,11322126 ! adrenal gland development GO:0030325 5 5 0,000 0,0194743 0,11286522 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0194743 0,11251141 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0194743 0,11215981 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0194743 0,11181041 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0194743 0,11146317 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0194743 0,11111808 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0194743 0,11077513 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0194743 0,11043428 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0194743 0,11009552 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0194743 0,10975884 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0194743 0,10942421 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0194743 0,10909161 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0194743 0,10876103 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0194743 0,10843245 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0194743 0,10810585 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0194743 0,1077812 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0194743 0,10745851 ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0194743 0,10713773 ! response to ATP GO:0033198 5 5 0,000 0,0194743 0,10681887 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0194743 0,1065019 ! regulation of appetite GO:0032098 5 5 0,000 0,0194743 0,10618681 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0194743 0,10587357 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0194743 0,10556218 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,0194743 0,10525261 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0194743 0,10494486 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0194743 0,10463889 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0194743 0,10433471 ! receptor clustering GO:0043113 5 5 0,000 0,0194743 0,10403229 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0194743 0,10373162 ! fear response GO:0042596 5 5 0,000 0,0194743 0,10343268 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0194743 0,10313546 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0194743 0,10283994 ! retinol metabolic process GO:0042572 5 5 0,000 0,0194743 0,10254612 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0194743 0,10225396 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0194743 0,10196347 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0194743 0,10167462 ! parturition GO:0007567 5 5 0,000 0,0194743 0,1013874 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0194743 0,1011018 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0194743 0,10081781 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0194743 0,10053541 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0194743 0,10025458 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0194743 0,09997532 ! protein heterooligomerization GO:0051291 5 5 0,000 0,0194743 0,09969761 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0194743 0,09942144 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0194743 0,0991468 ! response to UV-B GO:0010224 5 5 0,000 0,0194743 0,09887367 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0194743 0,09860203 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0194743 0,09833189 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0194743 0,09806323 ! interaction with symbiont GO:0051702 5 5 0,000 0,0194743 0,09779602 ! cellular extravasation GO:0045123 5 5 0,000 0,0194743 0,09753027 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0194743 0,09726596 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0194743 0,09700308 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0194743 0,09674162 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0194743 0,09648156 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0194743 0,0962229 ! response to amine stimulus GO:0014075 5 5 0,000 0,0194743 0,09596562 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0194743 0,09570971 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0194743 0,09545516 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0194743 0,09520196 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0194743 0,09495011 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0194743 0,09469958 ! neuron recognition GO:0008038 5 5 0,000 0,0194743 0,09445037 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,0194743 0,09420247 ! decidualization GO:0046697 5 5 0,000 0,0194743 0,09395587 ! hair follicle maturation GO:0048820 5 5 0,000 0,0194743 0,09371055 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0194743 0,09346651 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0194743 0,09322374 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0194743 0,09298223 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0194743 0,09274197 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0194743 0,09250294 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0194743 0,09226514 ! postreplication repair GO:0006301 5 5 0,000 0,0194743 0,09202857 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0194743 0,0917932 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0194743 0,09155903 ! histone methylation GO:0016571 5 5 0,000 0,0194743 0,09132606 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0194743 0,09109427 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0194743 0,09086365 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0194743 0,09063419 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0194743 0,0904059 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0194743 0,09017875 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0194743 0,08995273 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0194743 0,08972785 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0194743 0,08950409 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0194743 0,08928144 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0194743 0,0890599 ! sterol catabolic process GO:0016127 5 5 0,000 0,0194743 0,08883946 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0194743 0,0886201 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0194743 0,08840182 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0194743 0,08818462 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0194743 0,08796848 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0194743 0,0877534 ! zymogen activation GO:0031638 5 5 0,000 0,0194743 0,08753937 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0194743 0,08732638 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0194743 0,08711442 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0194743 0,08690349 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,0194743 0,08669358 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0194743 0,08648468 ! nucleosome positioning GO:0016584 5 5 0,000 0,0194743 0,08627678 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0194743 0,08606988 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0194743 0,08586397 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0194743 0,08565905 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0194743 0,0854551 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0194743 0,08525212 ! NADPH regeneration GO:0006740 5 5 0,000 0,0194743 0,0850501 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0194743 0,08484903 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0194743 0,08464892 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0194743 0,08444974 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0194743 0,0842515 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0194743 0,08405419 ! sarcomere organization GO:0045214 5 5 0,000 0,0194743 0,08385781 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0194743 0,08366233 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0194743 0,08346777 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0194743 0,08327411 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0194743 0,08308134 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0194743 0,08288947 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0194743 0,08269848 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0194743 0,08250837 ! spleen development GO:0048536 5 5 0,000 0,0194743 0,08231913 ! male genitalia development GO:0030539 5 5 0,000 0,0194743 0,08213076 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0194743 0,08194324 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0194743 0,08175658 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0194743 0,08157077 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0194743 0,08138581 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0194743 0,08120168 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0194743 0,08101838 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0194743 0,0808359 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0194743 0,08065425 ! ATP catabolic process GO:0006200 5 5 0,000 0,0194743 0,08047341 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0194743 0,08029338 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0194743 0,08011415 ! blastocyst formation GO:0001825 5 5 0,000 0,0194743 0,07993573 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0194743 0,07975809 ! embryonic gut development GO:0048566 5 5 0,000 0,0194743 0,07958124 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0194743 0,07940518 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0194743 0,07922989 ! activation of innate immune response GO:0002218 5 5 0,000 0,0194743 0,07905538 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,0194743 0,07888163 ! catecholamine transport GO:0051937 5 5 0,000 0,0194743 0,07870864 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0194743 0,07853641 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0194743 0,07836494 ! muscle adaptation GO:0043500 5 5 0,000 0,0194743 0,07819421 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0194743 0,07802422 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0194743 0,07785497 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0194743 0,07768645 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0194743 0,07751866 ! defense response to fungus GO:0050832 5 5 0,000 0,0194743 0,0773516 ! lysogeny GO:0030069 5 5 0,000 0,0194743 0,07718525 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0194743 0,07701962 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0194743 0,07685469 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0194743 0,07669047 ! response to nicotine GO:0035094 5 5 0,000 0,0194743 0,07652695 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0194743 0,07636413 ! mitochondrion localization GO:0051646 5 5 0,000 0,0194743 0,076202 ! nucleus localization GO:0051647 5 5 0,000 0,0194743 0,07604055 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0194743 0,07587979 ! regulation of nervous system development GO:0051960 57 56 1,000 0,02005156 0,07796418 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,0221183 0,08581899 ! regulation of cell development GO:0060284 60 59 1,000 0,0221183 0,08563869 ! protein localization in organelle GO:0033365 59 59 1,000 0,0221183 0,08545916 ! protein polymerization GO:0051258 65 60 1,000 0,02282619 0,08800977 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02332509 0,08974562 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02332509 0,08955865 ! tRNA modification GO:0006400 6 6 0,000 0,02332509 0,08937245 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02332509 0,08918703 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02332509 0,08900238 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02332509 0,08881849 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02332509 0,08863536 ! virus-host interaction GO:0019048 6 6 0,000 0,02332509 0,08845298 ! regulation of S phase GO:0033261 6 6 0,000 0,02332509 0,08827136 ! myotube differentiation GO:0014902 6 6 0,000 0,02332509 0,08809047 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02332509 0,08791033 ! bone remodeling GO:0046849 6 6 0,000 0,02332509 0,08773092 ! N-glycan processing GO:0006491 6 6 0,000 0,02332509 0,08755224 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02332509 0,08737429 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02332509 0,08719706 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02332509 0,08702055 ! RNA methylation GO:0001510 6 6 0,000 0,02332509 0,08684475 ! cartilage condensation GO:0001502 7 6 0,000 0,02332509 0,08666966 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02332509 0,08649527 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02332509 0,08632159 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02332509 0,0861486 ! artery development GO:0060840 6 6 0,000 0,02332509 0,0859763 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02332509 0,08580469 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02332509 0,08563377 ! androgen metabolic process GO:0008209 6 6 0,000 0,02332509 0,08546352 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02332509 0,08529395 ! limbic system development GO:0021761 7 6 0,000 0,02332509 0,08512505 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02332509 0,08495682 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02332509 0,08478925 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02332509 0,08462234 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02332509 0,08445609 ! pathogenesis GO:0009405 6 6 0,000 0,02332509 0,08429049 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02332509 0,08412554 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02332509 0,08396123 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02332509 0,08379756 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02332509 0,08363453 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02332509 0,08347214 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02332509 0,08331037 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02332509 0,08314923 ! arginine metabolic process GO:0006525 6 6 0,000 0,02332509 0,08298871 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02332509 0,08282881 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02332509 0,08266952 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02332509 0,08251084 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02332509 0,08235278 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02332509 0,08219532 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02332509 0,08203845 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02332509 0,08188219 ! V(D)J recombination GO:0033151 6 6 0,000 0,02332509 0,08172652 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02332509 0,08157144 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02332509 0,08141695 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02332509 0,08126304 ! regulation of heart rate GO:0002027 6 6 0,000 0,02332509 0,08110972 ! lipid digestion GO:0044241 6 6 0,000 0,02332509 0,08095697 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02332509 0,08080479 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02332509 0,08065319 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02332509 0,08050215 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02332509 0,08035168 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02332509 0,08020177 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02332509 0,08005242 ! ruffle organization GO:0031529 6 6 0,000 0,02332509 0,07990362 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02332509 0,07975538 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02332509 0,07960769 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02332509 0,07946054 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02332509 0,07931393 ! L-amino acid transport GO:0015807 6 6 0,000 0,02332509 0,07916786 ! bone mineralization GO:0030282 6 6 0,000 0,02332509 0,07902233 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02332509 0,07887734 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02332509 0,07873288 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02332509 0,07858894 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02332509 0,07844553 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02332509 0,07830264 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02332509 0,07816027 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02332509 0,07801842 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02332509 0,07787708 ! regulation of organ growth GO:0046620 6 6 0,000 0,02332509 0,07773626 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02332509 0,07759594 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02332509 0,07745613 ! response to dsRNA GO:0043331 6 6 0,000 0,02332509 0,07731682 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02332509 0,07717801 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02332509 0,0770397 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02332509 0,07690188 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02332509 0,07676455 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02332509 0,07662772 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02332509 0,07649137 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02332509 0,07635551 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02332509 0,07622012 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02332509 0,07608522 ! erythrocyte development GO:0048821 6 6 0,000 0,02332509 0,0759508 ! renal water homeostasis GO:0003091 6 6 0,000 0,02332509 0,07581684 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02332509 0,07568336 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02332509 0,07555035 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02332509 0,07541781 ! ribosome assembly GO:0042255 6 6 0,000 0,02332509 0,07528573 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02332509 0,07515411 ! diencephalon development GO:0021536 6 6 0,000 0,02332509 0,07502295 ! fucose catabolic process GO:0019317 6 6 0,000 0,02332509 0,07489225 GO:0042355|L-fucose catabolic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,02332509 0,074762 ! regulation of cell division GO:0051302 6 6 0,000 0,02332509 0,0746322 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02332509 0,07450286 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02332509 0,07437396 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02332509 0,07424551 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02332509 0,0741175 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02332509 0,07398993 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02332509 0,0738628 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02332509 0,07373611 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02332509 0,07360985 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02332509 0,07348402 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02332509 0,07335862 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02332509 0,07323365 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02332509 0,0731091 ! thymus development GO:0048538 6 6 0,000 0,02332509 0,07298497 ! lymph node development GO:0048535 6 6 0,000 0,02332509 0,07286127 ! organic cation transport GO:0015695 6 6 0,000 0,02332509 0,07273799 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02332509 0,07261512 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02332509 0,07249266 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,02332509 0,07237062 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02332509 0,07224899 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02332509 0,07212777 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02332509 0,07200695 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02332509 0,07188654 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02332509 0,07176653 ! alditol metabolic process GO:0019400 6 6 0,000 0,02332509 0,07164692 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02332509 0,0715277 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02332509 0,07140889 ! maternal placenta development GO:0001893 6 6 0,000 0,02332509 0,07129046 ! regulation of embryonic development GO:0045995 6 6 0,000 0,02332509 0,07117243 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02332509 0,07105479 ! localization within membrane GO:0051668 6 6 0,000 0,02332509 0,07093754 ! protein import GO:0017038 62 62 1,000 0,02426998 0,07368958 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02426998 0,07356838 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,02500572 0,07567412 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,02650449 0,08007833 ! respiratory burst GO:0045730 7 7 0,000 0,02716132 0,0819285 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02716132 0,08179463 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02716132 0,0816612 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02716132 0,0815282 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02716132 0,08139564 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02716132 0,0812635 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02716132 0,08113179 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02716132 0,08100051 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02716132 0,08086965 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02716132 0,08073922 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02716132 0,0806092 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02716132 0,08047961 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02716132 0,08035043 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02716132 0,08022166 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02716132 0,08009331 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02716132 0,07996536 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02716132 0,07983782 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02716132 0,07971069 ! axis specification GO:0009798 7 7 0,000 0,02716132 0,07958397 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02716132 0,07945764 ! visual behavior GO:0007632 7 7 0,000 0,02716132 0,07933172 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02716132 0,0792062 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02716132 0,07908107 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02716132 0,07895633 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02716132 0,07883199 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02716132 0,07870804 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02716132 0,07858448 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02716132 0,07846131 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02716132 0,07833852 ! digestive system development GO:0055123 7 7 0,000 0,02716132 0,07821612 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02716132 0,0780941 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02716132 0,07797245 ! protein targeting to ER GO:0045047 8 7 0,000 0,02716132 0,07785119 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02716132 0,0777303 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02716132 0,07760979 ! endoderm development GO:0007492 7 7 0,000 0,02716132 0,07748965 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02716132 0,07736989 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02716132 0,07725049 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02716132 0,07713146 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02716132 0,07701279 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02716132 0,07689449 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02716132 0,07677656 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02716132 0,07665898 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02716132 0,07654177 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02716132 0,07642491 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02716132 0,07630841 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02716132 0,07619226 ! UV protection GO:0009650 7 7 0,000 0,02716132 0,07607647 ! DNA integration GO:0015074 7 7 0,000 0,02716132 0,07596103 ! myofibril assembly GO:0030239 7 7 0,000 0,02716132 0,07584593 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02716132 0,07573119 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02716132 0,07561679 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02716132 0,07550274 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02716132 0,07538903 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02716132 0,07527566 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02716132 0,07516264 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02716132 0,07504995 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02716132 0,0749376 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02716132 0,07482558 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02716132 0,0747139 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02716132 0,07460256 ! axon cargo transport GO:0008088 7 7 0,000 0,02716132 0,07449154 ! eating behavior GO:0042755 7 7 0,000 0,02716132 0,07438086 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02716132 0,0742705 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02716132 0,07416047 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02716132 0,07405076 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02716132 0,07394138 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02716132 0,07383232 ! cranial nerve development GO:0021545 7 7 0,000 0,02716132 0,07372359 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02716132 0,07361517 ! induction of an organ GO:0001759 7 7 0,000 0,02716132 0,07350707 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02716132 0,07339929 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02716132 0,07329182 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02716132 0,07318467 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02716132 0,07307783 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02716132 0,07297131 ! platelet activation GO:0030168 8 7 0,000 0,02716132 0,07286509 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02716132 0,07275918 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02716132 0,07265358 ! natural killer cell activation GO:0030101 7 7 0,000 0,02716132 0,07254828 ! NADP metabolic process GO:0006739 7 7 0,000 0,02716132 0,07244329 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02716132 0,07233861 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02716132 0,07223422 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02716132 0,07213014 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02716132 0,07202635 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02716132 0,07192287 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02716132 0,07181968 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02716132 0,07171678 ! cell-cell recognition GO:0009988 8 7 0,000 0,02716132 0,07161419 ! hormone catabolic process GO:0042447 7 7 0,000 0,02716132 0,07151188 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02716132 0,07140987 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02716132 0,07130814 ! oxygen transport GO:0015671 7 7 0,000 0,02716132 0,07120671 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02716132 0,07110556 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02716132 0,0710047 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02716132 0,07090413 ! regulation of axon extension GO:0030516 7 7 0,000 0,02716132 0,07080384 ! cell killing GO:0001906 7 7 0,000 0,02716132 0,07070384 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02716132 0,07060411 ! adult feeding behavior GO:0008343 7 7 0,000 0,02716132 0,07050467 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02716132 0,07040551 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02716132 0,07030662 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02716132 0,07020802 ! response to cold GO:0009409 7 7 0,000 0,02716132 0,07010969 ! DNA packaging GO:0006323 66 66 1,000 0,02726737 0,07028499 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,02726737 0,07018683 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,02803915 0,07207274 ! response to radiation GO:0009314 70 68 1,000 0,02881975 0,07397603 ! regulation of translation GO:0006417 69 69 1,000 0,02960908 0,07589644 ! response to nutrient levels GO:0031667 69 69 1,000 0,02960908 0,07579103 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02960908 0,07568591 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03098304 0,07908828 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03098304 0,07897889 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03098304 0,0788698 ! positive regulation of translation GO:0045727 8 8 0,000 0,03098304 0,07876101 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03098304 0,07865253 ! superoxide anion generation GO:0042554 8 8 0,000 0,03098304 0,07854434 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03098304 0,07843645 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03098304 0,07832886 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03098304 0,07822156 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03098304 0,07811455 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03098304 0,07800784 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03098304 0,07790141 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03098304 0,07779528 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03098304 0,07768944 ! zinc ion transport GO:0006829 8 8 0,000 0,03098304 0,07758388 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03098304 0,07747861 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03098304 0,07737363 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03098304 0,07726893 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03098304 0,07716451 ! lipid localization GO:0010876 8 8 0,000 0,03098304 0,07706037 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03098304 0,07695652 ! response to cAMP GO:0051591 8 8 0,000 0,03098304 0,07685294 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03098304 0,07674964 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03098304 0,07664663 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03098304 0,07654388 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03098304 0,07644141 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03098304 0,07633922 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03098304 0,0762373 ! sensory perception of taste GO:0050909 8 8 0,000 0,03098304 0,07613565 ! organelle fusion GO:0048284 8 8 0,000 0,03098304 0,07603427 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03098304 0,07593316 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03098304 0,07583232 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03098304 0,07573175 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03098304 0,07563144 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03098304 0,0755314 ! sperm motility GO:0030317 8 8 0,000 0,03098304 0,07543162 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03098304 0,07533211 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03098304 0,07523285 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03098304 0,07513386 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03098304 0,07503513 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03098304 0,07493666 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03098304 0,07483845 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03098304 0,07474049 ! Golgi organization GO:0007030 8 8 0,000 0,03098304 0,07464279 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03098304 0,07454535 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03098304 0,07444816 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03098304 0,07435122 ! fructose metabolic process GO:0006000 8 8 0,000 0,03098304 0,07425453 ! mannose metabolic process GO:0006013 9 8 0,000 0,03098304 0,0741581 ! NAD metabolic process GO:0019674 8 8 0,000 0,03098304 0,07406191 ! sex determination GO:0007530 8 8 0,000 0,03098304 0,07396598 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03098304 0,07387029 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03098304 0,07377485 ! response to fungus GO:0009620 8 8 0,000 0,03098304 0,07367966 ! stem cell differentiation GO:0048863 8 8 0,000 0,03098304 0,07358471 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03098304 0,07349001 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03098304 0,07339555 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03098304 0,07330133 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03098304 0,07320735 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03098304 0,07311362 ! vasoconstriction GO:0042310 8 8 0,000 0,03098304 0,07302012 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03098304 0,07292687 ! muscle cell development GO:0055001 8 8 0,000 0,03098304 0,07283385 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03098304 0,07274106 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03098304 0,07264852 ! sensory perception of pain GO:0019233 8 8 0,000 0,03098304 0,07255621 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03098304 0,07246413 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03098304 0,07237229 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03098304 0,07228068 ! chromatin silencing GO:0006342 8 8 0,000 0,03098304 0,0721893 ! tissue regeneration GO:0042246 8 8 0,000 0,03098304 0,07209815 ! salivary gland development GO:0007431 8 8 0,000 0,03098304 0,07200723 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03098304 0,07191654 ! T cell homeostasis GO:0043029 8 8 0,000 0,03098304 0,07182608 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03098304 0,07173585 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03098304 0,07164584 ! water homeostasis GO:0030104 8 8 0,000 0,03098304 0,07155606 ! cofactor transport GO:0051181 8 8 0,000 0,03098304 0,0714665 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03098304 0,07137717 ! acid secretion GO:0046717 8 8 0,000 0,03098304 0,07128806 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03098304 0,07119917 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03098304 0,07111051 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03098304 0,07102206 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03098304 0,07093383 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03098304 0,07084583 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03098304 0,07075804 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03098304 0,07067047 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03098304 0,07058311 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,03098304 0,07049597 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03098304 0,07040905 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03098304 0,07032233 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03098304 0,07023584 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03098304 0,07014955 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03098304 0,07006348 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03098304 0,06997762 ! developmental induction GO:0031128 8 8 0,000 0,03098304 0,06989197 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03098304 0,06980652 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03098304 0,06972129 ! actin filament polymerization GO:0030041 9 8 0,000 0,03098304 0,06963626 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03098304 0,06955144 ! peptide hormone processing GO:0016486 8 8 0,000 0,03098304 0,06946683 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03098304 0,06938243 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03098304 0,06929822 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,03121369 0,06972949 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 1,000 0,03121369 0,06964508 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,03202881 0,07137738 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03202881 0,07129118 ! lactation GO:0007595 10 9 0,000 0,03479029 0,0773444 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03479029 0,07725121 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03479029 0,07715825 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03479029 0,07706551 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03479029 0,076973 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03479029 0,0768807 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03479029 0,07678863 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,03479029 0,07669678 ! viral genome replication GO:0019079 9 9 0,000 0,03479029 0,07660515 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03479029 0,07651373 ! copper ion transport GO:0006825 9 9 0,000 0,03479029 0,07642254 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03479029 0,07633156 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03479029 0,07624079 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03479029 0,07615025 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03479029 0,07605991 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03479029 0,0759698 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03479029 0,07587989 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03479029 0,0757902 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03479029 0,07570072 ! phospholipid efflux GO:0033700 9 9 0,000 0,03479029 0,07561145 ! response to alkaloid GO:0043279 10 9 0,000 0,03479029 0,07552239 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03479029 0,07543354 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03479029 0,0753449 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03479029 0,07525646 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03479029 0,07516824 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03479029 0,07508022 ! response to ethanol GO:0045471 9 9 0,000 0,03479029 0,07499241 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03479029 0,0749048 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03479029 0,07481739 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03479029 0,07473019 ! methionine metabolic process GO:0006555 9 9 0,000 0,03479029 0,0746432 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03479029 0,0745564 ! cerebral cortex development GO:0021987 9 9 0,000 0,03479029 0,07446981 ! response to osmotic stress GO:0006970 9 9 0,000 0,03479029 0,07438342 ! pigmentation during development GO:0048066 9 9 0,000 0,03479029 0,07429723 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03479029 0,07421124 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03479029 0,07412544 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03479029 0,07403985 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03479029 0,07395445 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03479029 0,07386925 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03479029 0,07378424 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03479029 0,07369943 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03479029 0,07361482 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03479029 0,0735304 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03479029 0,07344617 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03479029 0,07336214 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03479029 0,07327829 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03479029 0,07319464 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03479029 0,07311118 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03479029 0,07302791 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03479029 0,07294483 ! DNA replication initiation GO:0006270 9 9 0,000 0,03479029 0,07286194 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03479029 0,07277924 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03479029 0,07269672 ! histone acetylation GO:0016573 9 9 0,000 0,03479029 0,07261439 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03479029 0,07253225 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03479029 0,07245029 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03479029 0,07236852 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03479029 0,07228693 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03479029 0,07220553 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03479029 0,07212431 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03479029 0,07204327 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03479029 0,07196241 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03479029 0,07188173 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03479029 0,07180124 ! collagen catabolic process GO:0030574 9 9 0,000 0,03479029 0,07172093 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03479029 0,07164079 ! purine base metabolic process GO:0006144 9 9 0,000 0,03479029 0,07156083 ! gas transport GO:0015669 9 9 0,000 0,03479029 0,07148106 ! cholesterol efflux GO:0033344 9 9 0,000 0,03479029 0,07140146 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03479029 0,07132203 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03479029 0,07124279 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03479029 0,07116372 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03479029 0,07108482 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03479029 0,0710061 ! defense response to virus GO:0051607 9 9 0,000 0,03479029 0,07092755 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03479029 0,07084918 ! actin filament-based movement GO:0030048 9 9 0,000 0,03479029 0,07077098 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03479029 0,07069295 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,03622962 0,07353655 ! microtubule-based movement GO:0007018 82 78 1,000 0,03709431 0,07520882 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,03709431 0,07512617 ! metal ion homeostasis GO:0055065 78 78 1,000 0,03709431 0,07504371 ! nuclear transport GO:0051169 79 79 1,000 0,03796702 0,07672502 GO:0006913|nucleocytoplasmic transport, ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03858314 0,0778847 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03858314 0,07779948 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03858314 0,07771446 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03858314 0,07762961 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,03858314 0,07754496 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03858314 0,07746049 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03858314 0,0773762 ! neuron maturation GO:0042551 10 10 0,000 0,03858314 0,07729209 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03858314 0,07720817 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03858314 0,07712443 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03858314 0,07704087 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03858314 0,0769575 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03858314 0,0768743 ! hormone secretion GO:0046879 10 10 0,000 0,03858314 0,07679128 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03858314 0,07670844 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03858314 0,07662578 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03858314 0,0765433 ! inositol metabolic process GO:0006020 10 10 0,000 0,03858314 0,076461 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03858314 0,07637887 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03858314 0,07629692 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03858314 0,07621514 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03858314 0,07613354 ! glial cell development GO:0021782 10 10 0,000 0,03858314 0,07605211 ! phototransduction GO:0007602 11 10 0,000 0,03858314 0,07597086 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03858314 0,07588978 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03858314 0,07580888 ! fat cell differentiation GO:0045444 10 10 0,000 0,03858314 0,07572814 ! myoblast differentiation GO:0045445 10 10 0,000 0,03858314 0,07564758 ! centrosome cycle GO:0007098 10 10 0,000 0,03858314 0,07556719 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03858314 0,07548697 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03858314 0,07540692 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03858314 0,07532704 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03858314 0,07524733 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03858314 0,07516779 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03858314 0,07508841 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03858314 0,07500921 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03858314 0,07493017 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03858314 0,07485129 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,03858314 0,07477258 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03858314 0,07469404 GO:0030968|endoplasmic reticulum unfolded protein response, ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03858314 0,07461566 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03858314 0,07453745 ! exocrine system development GO:0035272 10 10 0,000 0,03858314 0,0744594 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03858314 0,07438151 ! embryo implantation GO:0007566 11 10 0,000 0,03858314 0,07430379 ! regulation of protein binding GO:0043393 11 10 0,000 0,03858314 0,07422623 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03858314 0,07414883 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03858314 0,07407159 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03858314 0,07399451 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03858314 0,0739176 ! protein export from nucleus GO:0006611 10 10 0,000 0,03858314 0,07384084 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03858314 0,07376424 ! cytolysis GO:0019835 10 10 0,000 0,03858314 0,0736878 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03858314 0,07361152 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03858314 0,0735354 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03858314 0,07345943 ! histone deacetylation GO:0016575 10 10 0,000 0,03858314 0,07338362 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03858314 0,07330797 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03858314 0,07323247 ! gland morphogenesis GO:0022612 10 10 0,000 0,03858314 0,07315713 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03858314 0,07308194 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03858314 0,07300691 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03858314 0,07293203 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03858314 0,0728573 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03858314 0,07278273 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03858314 0,07270831 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03858314 0,07263404 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03858314 0,07255993 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03858314 0,07248596 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03858314 0,07241215 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03858314 0,07233848 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03858314 0,07226497 ! nerve development GO:0021675 10 10 0,000 0,03858314 0,0721916 ! gut development GO:0048565 10 10 0,000 0,03858314 0,07211838 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03858314 0,07204532 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03858314 0,0719724 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03858314 0,07189962 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03858314 0,071827 ! protein stabilization GO:0050821 10 10 0,000 0,03858314 0,07175452 ! lymphocyte activation GO:0046649 82 81 1,000 0,03973618 0,07382437 ! protein secretion GO:0009306 11 11 0,000 0,04236163 0,07862285 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04236163 0,07854375 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04236163 0,07846482 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04236163 0,07838604 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04236163 0,07830741 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04236163 0,07822895 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04236163 0,07815064 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04236163 0,07807249 ! skin development GO:0043588 11 11 0,000 0,04236163 0,0779945 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04236163 0,07791666 ! signal complex assembly GO:0007172 11 11 0,000 0,04236163 0,07783897 ! microtubule-based transport GO:0010970 11 11 0,000 0,04236163 0,07776145 ! endothelial cell migration GO:0043542 11 11 0,000 0,04236163 0,07768407 ! peroxisomal transport GO:0043574 11 11 0,000 0,04236163 0,07760685 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04236163 0,07752978 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,04236163 0,07745287 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,04236163 0,07737611 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,04236163 0,0772995 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04236163 0,07722304 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 0,000 0,04236163 0,07714673 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04236163 0,07707057 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04236163 0,07699457 ! spinal cord development GO:0021510 11 11 0,000 0,04236163 0,07691871 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04236163 0,076843 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04236163 0,07676745 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,04236163 0,07669204 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04236163 0,07661677 ! digestive system process GO:0022600 11 11 0,000 0,04236163 0,07654166 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04236163 0,07646669 ! fucose metabolic process GO:0006004 11 11 0,000 0,04236163 0,07639187 ! membrane budding GO:0006900 11 11 0,000 0,04236163 0,0763172 ! monoamine transport GO:0015844 11 11 0,000 0,04236163 0,07624267 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04236163 0,07616828 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04236163 0,07609405 ! body fluid secretion GO:0007589 11 11 0,000 0,04236163 0,07601995 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04236163 0,075946 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04236163 0,0758722 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04236163 0,07579854 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,04236163 0,07572502 ! membrane depolarization GO:0051899 11 11 0,000 0,04236163 0,07565164 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04236163 0,0755784 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04236163 0,07550531 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,04236163 0,07543236 ! oogenesis GO:0048477 11 11 0,000 0,04236163 0,07535955 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04236163 0,07528688 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04236163 0,07521435 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,04236163 0,07514196 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,04236163 0,0750697 ! muscle maintenance GO:0046716 12 11 0,000 0,04236163 0,07499759 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04236163 0,07492562 ! hindbrain development GO:0030902 11 11 0,000 0,04236163 0,07485378 ! steroid catabolic process GO:0006706 11 11 0,000 0,04236163 0,07478208 ! endocrine process GO:0050886 11 11 0,000 0,04236163 0,07471052 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04236163 0,07463909 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04236163 0,07456781 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04236163 0,07449665 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,04336753 0,0761929 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 0,04429434 0,07774711 ! heart development GO:0007507 90 87 1,000 0,0452286 0,07931143 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04612583 0,08080789 ! translational initiation GO:0006413 12 12 0,000 0,04612583 0,08073115 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04612583 0,08065455 ! initiation of viral infection GO:0019059 12 12 0,000 0,04612583 0,0805781 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04612583 0,0805018 ! iron ion transport GO:0006826 13 12 0,000 0,04612583 0,08042564 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04612583 0,08034962 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04612583 0,08027375 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04612583 0,08019802 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04612583 0,08012243 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04612583 0,08004698 ! collagen metabolic process GO:0032963 12 12 0,000 0,04612583 0,07997168 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04612583 0,07989652 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04612583 0,0798215 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04612583 0,07974662 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04612583 0,07967188 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04612583 0,07959728 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04612583 0,07952282 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04612583 0,0794485 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04612583 0,07937432 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04612583 0,07930028 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04612583 0,07922637 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04612583 0,07915261 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04612583 0,07907897 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04612583 0,07900548 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,04612583 0,07893212 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04612583 0,0788589 ! vacuolar transport GO:0007034 12 12 0,000 0,04612583 0,07878582 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04612583 0,07871287 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04612583 0,07864005 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04612583 0,07856737 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04612583 0,07849483 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04612583 0,07842242 ! male gonad development GO:0008584 12 12 0,000 0,04612583 0,07835014 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04612583 0,07827799 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04612583 0,07820598 ! renal system process GO:0003014 12 12 0,000 0,04612583 0,0781341 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04612583 0,07806235 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04612583 0,07799073 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04612583 0,07791925 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04612583 0,07784789 ! pallium development GO:0021543 13 12 0,000 0,04612583 0,07777667 ! cell fate determination GO:0001709 12 12 0,000 0,04612583 0,07770557 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04612583 0,07763461 ! somitogenesis GO:0001756 13 12 0,000 0,04612583 0,07756378 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04612583 0,07749307 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04612583 0,07742249 ! detection of light stimulus GO:0009583 13 12 0,000 0,04612583 0,07735205 ! synaptogenesis GO:0007416 12 12 0,000 0,04612583 0,07728173 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04612583 0,07721153 ! hormone transport GO:0009914 12 12 0,000 0,04612583 0,07714147 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04612583 0,07707153 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04612583 0,07700172 ! spermatid differentiation GO:0048515 13 12 0,000 0,04612583 0,07693203 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04612583 0,07686248 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04612583 0,07679304 ! neural tube closure GO:0001843 13 12 0,000 0,04612583 0,07672373 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,04612583 0,07665455 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04612583 0,07658549 ! positive regulation of transferase activity GO:0051347 91 88 1,000 0,04617025 0,07659026 GO:0033674|positive regulation of kinase activity, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,04711922 0,07809418 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,04903884 0,08120269 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,04987577 0,0825144 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04987577 0,0824404 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04987577 0,08236652 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04987577 0,08229279 ! phenol metabolic process GO:0018958 13 13 0,000 0,04987577 0,08221918 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,04987577 0,0821457 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04987577 0,08207236 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04987577 0,08199914 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04987577 0,08192606 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04987577 0,08185311 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04987577 0,08178029 ! regeneration GO:0031099 13 13 0,000 0,04987577 0,08170759 ! keratinization GO:0031424 13 13 0,000 0,04987577 0,08163503 ! post-embryonic development GO:0009791 14 13 0,000 0,04987577 0,08156259 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04987577 0,08149028 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04987577 0,08141811 ! vasculogenesis GO:0001570 13 13 0,000 0,04987577 0,08134605 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04987577 0,08127413 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04987577 0,08120233 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,04987577 0,08113066 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04987577 0,08105912 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04987577 0,0809877 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04987577 0,08091641 ! autophagy GO:0006914 13 13 0,000 0,04987577 0,08084524 ! receptor metabolic process GO:0043112 14 13 0,000 0,04987577 0,0807742 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04987577 0,08070328 ! ureteric bud development GO:0001657 13 13 0,000 0,04987577 0,08063249 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04987577 0,08056182 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04987577 0,08049128 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04987577 0,08042086 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04987577 0,08035056 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04987577 0,08028039 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04987577 0,08021033 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04987577 0,0801404 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04987577 0,08007059 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04987577 0,08000091 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04987577 0,07993134 ! vasodilation GO:0042311 14 13 0,000 0,04987577 0,0798619 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04987577 0,07979257 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04987577 0,07972337 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04987577 0,07965428 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04987577 0,07958532 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04987577 0,07951647 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04987577 0,07944775 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04987577 0,07937914 ! immunoglobulin production GO:0002377 13 13 0,000 0,04987577 0,07931065 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04987577 0,07924228 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04987577 0,07917402 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04987577 0,07910589 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04987577 0,07903787 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04987577 0,07896997 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04987577 0,07890218 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04987577 0,07883451 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04987577 0,07876696 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04987577 0,07869952 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04987577 0,0786322 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04987577 0,07856499 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04987577 0,0784979 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04987577 0,07843092 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04987577 0,07836406 ! blastocyst development GO:0001824 13 13 0,000 0,04987577 0,07829731 ! telomere organization GO:0032200 13 13 0,000 0,04987577 0,07823067 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04987577 0,07816415 ! regulation of amine transport GO:0051952 13 13 0,000 0,04987577 0,07809774 ! tissue homeostasis GO:0001894 13 13 0,000 0,04987577 0,07803144 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04987577 0,07796526 ! neuron fate commitment GO:0048663 14 14 0,000 0,05361151 0,08373391 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05361151 0,08366301 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05361151 0,08359223 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05361151 0,08352157 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05361151 0,08345103 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05361151 0,08338061 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05361151 0,0833103 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05361151 0,08324012 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05361151 0,08317005 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05361151 0,0831001 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05361151 0,08303027 ! vesicle docking GO:0048278 14 14 0,000 0,05361151 0,08296055 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05361151 0,08289095 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05361151 0,08282147 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05361151 0,08275211 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05361151 0,08268286 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05361151 0,08261373 ! hair cycle GO:0042633 14 14 0,000 0,05361151 0,08254471 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05361151 0,08247581 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05361151 0,08240702 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05361151 0,08233835 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05361151 0,08226979 ! lysosome organization GO:0007040 14 14 0,000 0,05361151 0,08220135 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05361151 0,08213302 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05361151 0,0820648 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05361151 0,0819967 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05361151 0,0819287 ! primary neural tube formation GO:0014020 15 14 0,000 0,05361151 0,08186083 ! peptide cross-linking GO:0018149 14 14 0,000 0,05361151 0,08179306 ! regulation of behavior GO:0050795 14 14 0,000 0,05361151 0,08172541 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05361151 0,08165787 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05361151 0,08159044 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05361151 0,08152312 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05361151 0,08145591 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05361151 0,08138881 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,05361151 0,08132183 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05361151 0,08125495 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05361151 0,08118818 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05361151 0,08112153 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05361151 0,08105498 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05361151 0,08098854 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05361151 0,08092221 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05361151 0,08085599 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05361151 0,08078988 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05361151 0,08072387 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,05597828 0,08421875 ! anti-apoptosis GO:0006916 100 99 1,000 0,05699679 0,08568115 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05733311 0,08611648 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05733311 0,08604635 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05733311 0,08597634 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05733311 0,08590644 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05733311 0,08583665 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05733311 0,08576698 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05733311 0,08569742 ! response to vitamin GO:0033273 15 15 0,000 0,05733311 0,08562798 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,05733311 0,08555864 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05733311 0,08548942 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05733311 0,08542031 ! ovarian follicle development GO:0001541 15 15 0,000 0,05733311 0,08535131 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05733311 0,08528242 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05733311 0,08521365 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05733311 0,08514498 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05733311 0,08507643 ! heme metabolic process GO:0042168 15 15 0,000 0,05733311 0,08500798 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05733311 0,08493965 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05733311 0,08487142 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05733311 0,08480331 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05733311 0,0847353 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05733311 0,08466741 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05733311 0,08459962 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05733311 0,08453194 ! phospholipid transport GO:0015914 15 15 0,000 0,05733311 0,08446437 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05733311 0,0843969 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05733311 0,08432955 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05733311 0,0842623 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05733311 0,08419516 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05733311 0,08412812 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05733311 0,08406119 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05733311 0,08399437 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05733311 0,08392766 ! protein homooligomerization GO:0051260 15 15 0,000 0,05733311 0,08386105 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05733311 0,08379455 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06104061 0,08914251 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06104061 0,08907193 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06104061 0,08900146 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06104061 0,08893111 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06104061 0,08886086 ! learning GO:0007612 16 16 0,000 0,06104061 0,08879073 ! circadian rhythm GO:0007623 16 16 0,000 0,06104061 0,0887207 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06104061 0,08865079 ! vacuole organization GO:0007033 16 16 0,000 0,06104061 0,08858098 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06104061 0,08851129 ! vesicle targeting GO:0006903 17 16 0,000 0,06104061 0,08844171 ! segmentation GO:0035282 17 16 0,000 0,06104061 0,08837223 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06104061 0,08830286 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06104061 0,08823361 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06104061 0,08816446 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06104061 0,08809542 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06104061 0,08802649 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06104061 0,08795766 ! cell fate specification GO:0001708 16 16 0,000 0,06104061 0,08788894 ! pentose metabolic process GO:0019321 16 16 0,000 0,06104061 0,08782034 ! fatty acid transport GO:0015908 16 16 0,000 0,06104061 0,08775183 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06104061 0,08768344 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06104061 0,08761515 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06104061 0,08754696 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06104061 0,08747889 ! polyol metabolic process GO:0019751 16 16 0,000 0,06104061 0,08741092 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06104061 0,08734305 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06104061 0,08727529 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06104061 0,08720764 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06104061 0,08714008 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,06104061 0,08707264 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06104061 0,0870053 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06104061 0,08693806 ! regulation of coagulation GO:0050818 17 16 0,000 0,06104061 0,08687093 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06473407 0,09205625 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,06473407 0,09198527 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06473407 0,0919144 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06473407 0,09184364 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06473407 0,091773 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06473407 0,09170246 ! leukocyte adhesion GO:0007159 17 17 0,000 0,06473407 0,09163202 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06473407 0,0915617 ! sensory perception of smell GO:0007608 17 17 0,000 0,06473407 0,09149148 ! tissue remodeling GO:0048771 17 17 0,000 0,06473407 0,09142138 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06473407 0,09135137 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06473407 0,09128148 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06473407 0,09121169 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06473407 0,09114201 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06473407 0,09107244 ! neural crest cell development GO:0014032 19 17 0,000 0,06473407 0,09100297 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06473407 0,09093361 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06473407 0,09086435 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,06473407 0,0907952 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06473407 0,09072616 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,06473407 0,09065721 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06473407 0,09058838 ! pigmentation GO:0043473 17 17 0,000 0,06473407 0,09051965 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06473407 0,09045102 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06473407 0,0903825 ! embryonic organ development GO:0048568 17 17 0,000 0,06473407 0,09031408 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06473407 0,09024576 ! liver development GO:0001889 17 17 0,000 0,06473407 0,09017755 ! gene silencing GO:0016458 17 17 0,000 0,06473407 0,09010944 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06841354 0,09515936 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06841354 0,0950876 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,06841354 0,09501594 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06841354 0,09494439 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,06841354 0,09487295 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06841354 0,09480162 ! membrane docking GO:0022406 18 18 0,000 0,06841354 0,09473039 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06841354 0,09465927 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06841354 0,09458826 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06841354 0,09451736 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06841354 0,09444656 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06841354 0,09437586 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,06841354 0,09430527 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06841354 0,09423479 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06841354 0,09416442 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06841354 0,09409414 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06841354 0,09402398 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06841354 0,09395391 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06841354 0,09388396 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06841354 0,0938141 ! BMP signaling pathway GO:0030509 18 18 0,000 0,06841354 0,09374435 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06841354 0,0936747 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06841354 0,09360516 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,06841354 0,09353572 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06841354 0,09346638 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07207906 0,09840127 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07207906 0,09832843 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07207906 0,09825571 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07207906 0,09818309 ! feeding behavior GO:0007631 19 19 0,000 0,07207906 0,09811057 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,07207906 0,09803817 ! peroxisome organization GO:0007031 19 19 0,000 0,07207906 0,09796587 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07207906 0,09789367 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07207906 0,09782159 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07207906 0,09774961 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,07207906 0,09767773 ! metanephros development GO:0001656 19 19 0,000 0,07207906 0,09760596 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,07207906 0,0975343 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07207906 0,09746274 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,07207906 0,09739129 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07207906 0,09731994 ! regulation of protein stability GO:0031647 19 19 0,000 0,07207906 0,09724869 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07207906 0,09717755 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07207906 0,09710652 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,07207906 0,09703558 ! eye morphogenesis GO:0048592 19 19 0,000 0,07207906 0,09696476 ! regulation of cell shape GO:0008360 21 19 0,000 0,07207906 0,09689403 ! placenta development GO:0001890 19 19 0,000 0,07207906 0,09682341 ! response to heat GO:0009408 19 19 0,000 0,07207906 0,09675289 ! vesicle localization GO:0051648 20 19 0,000 0,07207906 0,09668247 ! regulation of muscle development GO:0048634 21 20 0,000 0,0757307 0,10150667 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,0757307 0,10143291 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0757307 0,10135924 ! negative regulation of binding GO:0051100 21 20 0,000 0,0757307 0,10128569 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0757307 0,10121224 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,0757307 0,1011389 ! neural tube development GO:0021915 21 20 0,000 0,0757307 0,10106566 ! phagocytosis GO:0006909 21 20 0,000 0,0757307 0,10099253 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0757307 0,10091951 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0757307 0,10084659 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,0757307 0,10077377 ! chromatin remodeling GO:0006338 20 20 0,000 0,0757307 0,10070107 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,0757307 0,10062846 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,0757307 0,10055596 ! lipid oxidation GO:0034440 20 20 0,000 0,0757307 0,10048357 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,0757307 0,10041128 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0757307 0,10033909 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0757307 0,10026701 ! RNA modification GO:0009451 20 20 0,000 0,0757307 0,10019503 ! single fertilization GO:0007338 21 20 0,000 0,0757307 0,10012315 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0757307 0,10005138 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07936849 0,10478233 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,07936849 0,10470733 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07936849 0,10463243 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,07936849 0,10455764 ! ear morphogenesis GO:0042471 21 21 0,000 0,07936849 0,10448295 ! organic anion transport GO:0015711 21 21 0,000 0,07936849 0,10440837 ! cholesterol transport GO:0030301 21 21 0,000 0,07936849 0,1043339 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07936849 0,10425954 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07936849 0,10418528 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,07936849 0,10411113 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07936849 0,10403708 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,07936849 0,10396314 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,07936849 0,1038893 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07936849 0,10381557 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,07936849 0,10374194 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,07936849 0,10366841 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,0829925 0,10832519 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,0829925 0,10824853 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,0829925 0,10817198 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,0829925 0,10809553 ! regulation of ion transport GO:0043269 22 22 0,000 0,0829925 0,10801919 ! odontogenesis GO:0042476 22 22 0,000 0,0829925 0,10794296 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,0829925 0,10786684 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,0829925 0,10779082 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,0829925 0,10771491 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,0829925 0,10763911 ! ovulation cycle process GO:0022602 22 22 0,000 0,0829925 0,10756341 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,0829925 0,10748782 ! cell chemotaxis GO:0060326 23 22 0,000 0,0829925 0,10741234 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,0829925 0,10733696 ! male sex differentiation GO:0046661 22 22 0,000 0,0829925 0,10726169 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,0829925 0,10718653 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,0829925 0,10711147 ! detection of external stimulus GO:0009581 23 22 0,000 0,0829925 0,10703651 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,0829925 0,10696166 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,0829925 0,10688691 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,0829925 0,10681227 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,0829925 0,10673774 ! aerobic respiration GO:0009060 22 22 0,000 0,0829925 0,1066633 ! cytokine production GO:0001816 22 22 0,000 0,0829925 0,10658897 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,0829925 0,10651475 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08660276 0,11107091 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08660276 0,11099367 ! viral infectious cycle GO:0019058 23 23 0,000 0,08660276 0,11091654 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,08660276 0,11083951 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,08660276 0,11076259 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08660276 0,11068578 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08660276 0,11060907 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08660276 0,11053248 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08660276 0,11045598 ! positive regulation of growth GO:0045927 23 23 0,000 0,08660276 0,11037959 ! female gonad development GO:0008585 23 23 0,000 0,08660276 0,11030331 ! lipid homeostasis GO:0055088 23 23 0,000 0,08660276 0,11022714 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,08660276 0,11015107 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08660276 0,1100751 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,08660276 0,10999924 ! cell projection assembly GO:0030031 25 23 0,000 0,08660276 0,10992348 ! gliogenesis GO:0042063 24 24 0,000 0,09019934 0,11440976 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,09019934 0,11433108 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,09019934 0,1142525 ! glucose homeostasis GO:0042593 24 24 0,000 0,09019934 0,11417403 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,09019934 0,11409567 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,09019934 0,11401741 ! ovulation cycle GO:0042698 24 24 0,000 0,09019934 0,11393926 ! fertilization GO:0009566 25 24 0,000 0,09019934 0,11386122 ! maintenance of protein location GO:0045185 25 24 0,000 0,09019934 0,11378329 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,09019934 0,11370546 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,09019934 0,11362774 ! glucan metabolic process GO:0044042 25 24 0,000 0,09019934 0,11355013 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09378228 0,11798003 ! negative regulation of secretion GO:0051048 26 25 0,000 0,09378228 0,11789955 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09378228 0,11781918 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09378228 0,11773892 ! cellular component disassembly GO:0022411 26 25 0,000 0,09378228 0,11765877 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,09378228 0,11757873 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,09378228 0,1174988 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,09378228 0,11741898 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09378228 0,11733927 ! excretion GO:0007588 25 25 0,000 0,09378228 0,11725966 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,09378228 0,11718016 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09378228 0,11710077 ! gastrulation GO:0007369 25 25 0,000 0,09378228 0,11702149 ! heart morphogenesis GO:0003007 25 25 0,000 0,09378228 0,11694231 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,09378228 0,11686324 ! regulation of endocytosis GO:0030100 25 25 0,000 0,09378228 0,11678428 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,09378228 0,11670543 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,09378228 0,11662668 ! positive regulation of binding GO:0051099 27 26 0,000 0,09735163 0,12098385 ! positive regulation of defense response GO:0031349 26 26 0,000 0,09735163 0,12090232 ! glycolysis GO:0006096 26 26 0,000 0,09735163 0,12082091 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,09735163 0,1207396 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,09735163 0,1206584 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09735163 0,12057732 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,09735163 0,12049634 ! cellular defense response GO:0006968 26 26 0,000 0,09735163 0,12041547 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09735163 0,12033471 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09735163 0,12025405 ! germ cell development GO:0007281 27 26 0,000 0,09735163 0,12017351 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09735163 0,12009307 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,09735163 0,12001274 ! maintenance of location in cell GO:0051651 27 26 0,000 0,09735163 0,11993252 ! chloride transport GO:0006821 27 27 0,000 0,10090743 0,12423006 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,10090743 0,12414713 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,10090743 0,12406431 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,10090743 0,1239816 ! learning or memory GO:0007611 28 27 0,000 0,10090743 0,123899 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,10090743 0,12381651 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,10090743 0,12373413 ! peptide metabolic process GO:0006518 29 27 0,000 0,10090743 0,12365186 ! inner ear development GO:0048839 27 27 0,000 0,10090743 0,1235697 ! defense response to bacterium GO:0042742 27 27 0,000 0,10090743 0,12348765 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,10090743 0,12340571 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,10090743 0,12332387 ! cell growth GO:0016049 27 27 0,000 0,10090743 0,12324215 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10444975 0,12748403 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,10444975 0,12739966 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,10444975 0,1273154 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10444975 0,12723126 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,10444975 0,12714722 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10444975 0,12706329 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,10444975 0,12697948 ! histone modification GO:0016570 28 28 0,000 0,10444975 0,12689577 ! developmental growth GO:0048589 28 28 0,000 0,10444975 0,12681218 ! cartilage development GO:0051216 29 28 0,000 0,10444975 0,1267287 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10797863 0,13092408 ! viral reproductive process GO:0022415 29 29 0,000 0,10797863 0,13083801 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,10797863 0,13075204 ! leukocyte migration GO:0050900 30 29 0,000 0,10797863 0,13066619 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,10797863 0,13058045 ! antigen processing and presentation GO:0019882 29 29 0,000 0,10797863 0,13049482 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,10797863 0,13040931 ! tRNA processing GO:0008033 29 29 0,000 0,10797863 0,13032391 ! covalent chromatin modification GO:0016569 29 29 0,000 0,10797863 0,13023862 ! adult behavior GO:0030534 30 29 0,000 0,10797863 0,13015344 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10797863 0,13006837 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,10797863 0,12998341 ! transition metal ion transport GO:0000041 31 30 0,000 0,11149411 0,1341277 ! RNA catabolic process GO:0006401 30 30 0,000 0,11149411 0,13404021 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,11149411 0,13395283 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,11149411 0,13386557 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,11149411 0,13377841 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,11149411 0,13369138 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,11149411 0,13360445 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,11149411 0,13351764 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,11149411 0,13343094 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,11149411 0,13334435 ! response to temperature stimulus GO:0009266 30 30 0,000 0,11149411 0,13325788 ! regulation of ossification GO:0030278 30 30 0,000 0,11149411 0,13317151 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,11149411 0,13308526 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,11149411 0,13299912 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,11149411 0,13291309 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,11149411 0,13282718 ! vesicle organization GO:0016050 30 30 0,000 0,11149411 0,13274137 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,11149411 0,13265568 ! regulation of translational initiation GO:0006446 31 31 0,000 0,11499625 0,13673425 ! membrane fusion GO:0006944 31 31 0,000 0,11499625 0,13664609 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11499625 0,13655805 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,11499625 0,13647011 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11499625 0,1363823 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11499625 0,13629459 ! digestion GO:0007586 31 31 0,000 0,11499625 0,136207 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11499625 0,13611952 ! regulation of heart contraction GO:0008016 31 31 0,000 0,11499625 0,13603215 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11499625 0,13594489 ! camera-type eye development GO:0043010 31 31 0,000 0,11499625 0,13585775 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11499625 0,13577072 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,11499625 0,1356838 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,11499625 0,13559699 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,11499625 0,13551029 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11848509 0,13953229 ! glucose catabolic process GO:0006007 32 32 0,000 0,11848509 0,13944319 ! lipid modification GO:0030258 32 32 0,000 0,11848509 0,1393542 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,11848509 0,13926533 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11848509 0,13917656 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,11848509 0,13908792 ! cell maturation GO:0048469 32 32 0,000 0,11848509 0,13899938 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,11848509 0,13891096 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,11848509 0,13882265 ! nuclear export GO:0051168 32 32 0,000 0,11848509 0,13873445 ! kidney development GO:0001822 32 32 0,000 0,11848509 0,13864637 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,11848509 0,13855839 ! maintenance of location GO:0051235 33 32 0,000 0,11848509 0,13847053 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,12196069 0,14244205 ! amino acid transport GO:0006865 33 33 0,000 0,12196069 0,14235184 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,12196069 0,14226175 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,12196069 0,14217176 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,12196069 0,1420819 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,12196069 0,14199214 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,12196069 0,1419025 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,12196069 0,14181297 ! regulation of actin filament length GO:0030832 34 34 0,000 0,1254231 0,14574701 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,1254231 0,14565518 ! response to metal ion GO:0010038 34 34 0,000 0,1254231 0,14556345 ! ear development GO:0043583 34 34 0,000 0,1254231 0,14547185 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,1254231 0,14538036 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,1254231 0,14528898 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,1254231 0,14519772 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,1254231 0,14510657 ! secondary metabolic process GO:0019748 34 34 0,000 0,1254231 0,14501554 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,1254231 0,14492462 ! viral reproduction GO:0016032 34 34 0,000 0,1254231 0,14483381 ! detection of stimulus GO:0051606 36 34 0,000 0,1254231 0,14474312 ! acute inflammatory response GO:0002526 35 35 0,000 0,12887235 0,14863062 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,12887235 0,14853767 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12887235 0,14844483 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12887235 0,14835211 ! mesoderm development GO:0007498 35 35 0,000 0,12887235 0,14825951 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,12887235 0,14816702 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,12887235 0,14807465 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,12887235 0,14798239 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,12887235 0,14789025 ! inorganic anion transport GO:0015698 35 35 0,000 0,12887235 0,14779822 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,12887235 0,1477063 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12887235 0,1476145 ! hydrogen transport GO:0006818 36 36 0,000 0,1323085 0,15145625 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1323085 0,15136223 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1323085 0,15126834 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1323085 0,15117456 ! positive regulation of cell migration GO:0030335 36 36 0,000 0,1323085 0,15108089 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1323085 0,15098734 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,1323085 0,15089391 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,1323085 0,15080059 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1323085 0,15070739 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1323085 0,1506143 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,1323085 0,15052133 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,1323085 0,15042848 ! gonad development GO:0008406 36 36 0,000 0,1323085 0,15033573 ! regulation of lipase activity GO:0060191 36 36 0,000 0,1323085 0,15024311 ! activation of immune response GO:0002253 36 36 0,000 0,1323085 0,15015059 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,13573159 0,15394051 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,13573159 0,15384583 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 0,000 0,13573159 0,15375128 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,13573159 0,15365683 ! eye development GO:0001654 37 37 0,000 0,13573159 0,15356251 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13573159 0,1534683 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13573159 0,1533742 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,13573159 0,15328022 ! adaptive immune response GO:0002250 37 37 0,000 0,13573159 0,15318636 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,13914168 0,15693888 ! neurotransmitter transport GO:0006836 40 38 0,000 0,13914168 0,15684289 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,13914168 0,15674702 ! exocytosis GO:0006887 40 38 0,000 0,13914168 0,15665127 ! urogenital system development GO:0001655 38 38 0,000 0,13914168 0,15655563 ! hexose catabolic process GO:0019320 38 38 0,000 0,13914168 0,15646011 ! RNA elongation GO:0006354 38 38 0,000 0,13914168 0,15636471 ! regulation of neurological system process GO:0031644 38 38 0,000 0,13914168 0,15626942 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,13914168 0,15617425 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,14253881 0,15988986 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,14253881 0,1597926 ! activation of MAPK activity GO:0000187 39 39 0,000 0,14253881 0,15969546 ! respiratory tube development GO:0030323 40 39 0,000 0,14253881 0,15959844 ! response to unfolded protein GO:0006986 39 39 0,000 0,14253881 0,15950154 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,14253881 0,15940475 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,14253881 0,15930809 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,14253881 0,15921154 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,14253881 0,1591151 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,14253881 0,15901879 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,14253881 0,15892259 ! respiratory system development GO:0060541 40 39 0,000 0,14253881 0,1588265 ! developmental maturation GO:0021700 39 39 0,000 0,14253881 0,15873054 ! limb development GO:0060173 39 39 0,000 0,14253881 0,15863468 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! positive regulation of cell motion GO:0051272 39 39 0,000 0,14253881 0,15853895 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,14592304 0,16220516 ! DNA catabolic process GO:0006308 41 40 0,000 0,14592304 0,16210739 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,14929439 0,16575275 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,14929439 0,16565296 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14929439 0,16555329 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14929439 0,16545374 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,14929439 0,16535431 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14929439 0,16525499 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,14929439 0,1651558 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,15265293 0,16876986 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,15265293 0,16866868 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,15265293 0,16856762 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,15265293 0,16846668 ! protein ubiquitination GO:0016567 43 42 0,000 0,15265293 0,16836586 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,15265293 0,16826516 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,15265293 0,16816459 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,15265293 0,16806413 ! reproductive structure development GO:0048608 43 43 0,000 0,1559987 0,17164514 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1559987 0,17154272 ! alcohol catabolic process GO:0046164 43 43 0,000 0,1559987 0,17144043 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,1559987 0,17133826 ! humoral immune response GO:0006959 44 44 0,000 0,15933175 0,17489482 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,15933175 0,17479072 ! mRNA transport GO:0051028 44 44 0,000 0,15933175 0,17468674 ! vitamin metabolic process GO:0006766 44 44 0,000 0,15933175 0,17458288 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,15933175 0,17447915 ! amine biosynthetic process GO:0009309 46 45 0,000 0,16265212 0,17800941 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,16265212 0,17790377 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,16265212 0,17779825 ! regulation of DNA binding GO:0051101 47 45 0,000 0,16265212 0,17769286 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,16265212 0,17758759 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,16265212 0,17748244 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16595985 0,18098462 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,16595985 0,18087759 ! tube morphogenesis GO:0035239 47 46 0,000 0,16595985 0,18077069 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,16595985 0,18066392 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,16595985 0,18055727 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,16595985 0,18045074 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,16925501 0,18392511 ! regulation of blood pressure GO:0008217 48 47 0,000 0,16925501 0,18381672 ! sex differentiation GO:0007548 47 47 0,000 0,16925501 0,18370847 ! amine transport GO:0015837 47 47 0,000 0,16925501 0,18360034 ! rhythmic process GO:0048511 47 47 0,000 0,16925501 0,18349234 ! regulation of catabolic process GO:0009894 48 47 0,000 0,16925501 0,18338447 ! calcium ion transport GO:0006816 48 48 0,000 0,17253762 0,18683128 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,17253762 0,18672157 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,17253762 0,186612 ! DNA recombination GO:0006310 48 48 0,000 0,17253762 0,18650255 ! ossification GO:0001503 50 49 0,000 0,17580775 0,18992595 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,17580775 0,18981469 ! divalent metal ion transport GO:0070838 49 49 0,000 0,17580775 0,18970356 ! response to nutrient GO:0007584 49 49 0,000 0,17580775 0,18959256 ! response to bacterium GO:0009617 50 49 0,000 0,17580775 0,18948168 ! regulation of ligase activity GO:0051340 50 49 0,000 0,17580775 0,18937094 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,17580775 0,18926033 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,17580775 0,18914984 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,17906542 0,19254234 ! negative regulation of transport GO:0051051 51 50 0,000 0,17906542 0,19243007 ! chromatin assembly GO:0031497 50 50 0,000 0,17906542 0,19231794 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,17906542 0,19220593 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17906542 0,19209405 ! transcription initiation GO:0006352 50 50 0,000 0,17906542 0,1919823 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,17906542 0,19187068 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,17906542 0,1917592 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,1823107 0,19512115 ! positive regulation of immune response GO:0050778 51 51 0,000 0,1823107 0,19500791 ! rRNA metabolic process GO:0016072 51 51 0,000 0,1823107 0,19489479 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,1823107 0,19478181 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,1823107 0,19466896 ! RNA localization GO:0006403 52 52 0,000 0,18554362 0,19800631 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,18554362 0,19789172 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,18554362 0,19777727 ! sodium ion transport GO:0006814 53 53 0,000 0,18876423 0,20109392 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18876423 0,20097774 ! response to hypoxia GO:0001666 53 53 0,000 0,18876423 0,20086171 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18876423 0,2007458 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,18876423 0,20063003 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,18876423 0,2005144 ! regulation of protein transport GO:0051223 53 53 0,000 0,18876423 0,20039889 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,19197257 0,20368765 ! response to oxygen levels GO:0070482 55 54 0,000 0,19197257 0,20357046 ! response to virus GO:0009615 54 54 0,000 0,19197257 0,2034534 ! hormone metabolic process GO:0042445 55 54 0,000 0,19197257 0,20333647 ! sulfur metabolic process GO:0006790 55 54 0,000 0,19197257 0,20321968 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,19197257 0,20310302 ! nucleosome organization GO:0034728 55 55 0,000 0,1951687 0,20636598 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,1951687 0,20624766 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,19835265 0,20949222 ! reproductive developmental process GO:0003006 56 56 0,000 0,19835265 0,20937224 ! regulation of binding GO:0051098 60 57 0,000 0,20152446 0,2125985 ! ATP metabolic process GO:0046034 57 57 0,000 0,20152446 0,21247688 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,20152446 0,21235539 ! regulation of protein localization GO:0032880 58 57 0,000 0,20152446 0,21223405 ! innate immune response GO:0045087 58 58 0,000 0,20468419 0,21543859 ! dephosphorylation GO:0016311 60 59 0,000 0,20783188 0,2186268 ! carboxylic acid transport GO:0046942 59 59 0,000 0,20783188 0,21850209 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,20783188 0,21837751 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,20783188 0,21825308 ! immune effector process GO:0002252 59 59 0,000 0,20783188 0,21812879 ! potassium ion transport GO:0006813 60 60 0,000 0,21096757 0,22129381 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,21096757 0,22116794 ! cellular respiration GO:0045333 62 61 0,000 0,21409131 0,22431511 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,21409131 0,22418766 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,21409131 0,22406035 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,21409131 0,22393319 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,21409131 0,22380617 ! lipid transport GO:0006869 62 62 0,000 0,21720313 0,22693048 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,21720313 0,22680191 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,21720313 0,22667348 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,21720313 0,2265452 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21720313 0,22641706 ! regulation of secretion GO:0051046 65 63 0,000 0,22030309 0,22951871 ! glucose metabolic process GO:0006006 63 63 0,000 0,22030309 0,22938904 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,22030309 0,22925951 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,22030309 0,22913013 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,22339122 0,23221096 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,22339122 0,23208006 ! angiogenesis GO:0001525 65 64 0,000 0,22339122 0,23194931 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,22339122 0,23181871 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,22339122 0,23168825 ! anion transport GO:0006820 65 65 0,000 0,22646758 0,23474677 ! regulation of hormone levels GO:0010817 66 65 0,000 0,22646758 0,23461481 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,2295322 0,23765609 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,2295322 0,23752265 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,2295322 0,23738936 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,2295322 0,23725622 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,23258512 0,24027712 ! muscle contraction GO:0006936 67 67 0,000 0,23258512 0,24014251 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,23258512 0,24000805 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,2356264 0,24301032 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,2356264 0,24287441 ! sensory perception of sound GO:0007605 71 69 0,000 0,23865606 0,24585977 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,23865606 0,24572242 ! positive regulation of transport GO:0051050 71 70 0,000 0,24167416 0,24869095 ! growth GO:0040007 70 70 0,000 0,24167416 0,24855217 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,24167416 0,24841354 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,24468074 0,25136377 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,24468074 0,25122374 ! regulation of cell migration GO:0030334 71 71 0,000 0,24468074 0,25108386 ! ribosome biogenesis GO:0042254 71 71 0,000 0,24468074 0,25094413 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,24468074 0,25080457 ! secretion by cell GO:0032940 75 72 0,000 0,24767584 0,2537335 ! muscle system process GO:0003012 72 72 0,000 0,24767584 0,25359254 ! sensory organ development GO:0007423 72 72 0,000 0,24767584 0,25345173 ! regulation of cytokine production GO:0001817 72 72 0,000 0,24767584 0,25331108 ! electron transport chain GO:0022900 75 74 0,000 0,25363176 0,25925865 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,25363176 0,25911493 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,25659267 0,26199462 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,25659267 0,26184955 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,25954227 0,264713 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,25954227 0,26456659 ! regulation of protein modification process GO:0031399 79 78 0,000 0,26540769 0,270396 ! regulation of immune response GO:0050776 78 78 0,000 0,26540769 0,27024661 ! regulation of locomotion GO:0040012 79 79 0,000 0,26832359 0,27306481 ! regulation of cell motion GO:0051270 79 79 0,000 0,26832359 0,27291412 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,27122835 0,27571641 ! MAPKKK cascade GO:0000165 82 81 0,000 0,274122 0,27850433 ! tube development GO:0035295 83 81 0,000 0,274122 0,27835088 ! lipid catabolic process GO:0016042 82 81 0,000 0,274122 0,2781976 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,27987615 0,28388098 ! ncRNA processing GO:0034470 83 83 0,000 0,27987615 0,28372483 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,27987615 0,28356885 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,28273673 0,28630977 ! regulation of cellular localization GO:0060341 86 85 0,000 0,28558636 0,28903661 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,28558636 0,28887797 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,28842509 0,29158938 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,28842509 0,29142952 ! male gamete generation GO:0048232 90 88 0,000 0,29407 0,29697042 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,29407 0,29680778 ! chemotaxis GO:0006935 90 89 0,000 0,29687626 0,29947616 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,29967177 0,30213079 ! visual perception GO:0007601 93 92 0,000 0,30523073 0,3075671 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,30523073 0,30739903 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,30523073 0,30723115 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,30523073 0,30706345 ! tissue morphogenesis GO:0048729 94 93 0,000 0,30799425 0,30967452 ! regulation of response to stress GO:0080134 97 94 0,000 0,31074718 0,31227211 ! blood vessel development GO:0001568 95 94 0,000 0,31074718 0,31210194 ! pattern specification process GO:0007389 96 94 0,000 0,31074718 0,31193195 ! epidermis development GO:0008544 94 94 0,000 0,31074718 0,31176214 ! cofactor metabolic process GO:0051186 95 94 0,000 0,31074718 0,31159252 ! vasculature development GO:0001944 97 96 0,000 0,31622144 0,31690925 ! blood circulation GO:0008015 99 98 0,000 0,32165382 0,32217826 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,32165382 0,32200326 ! ectoderm development GO:0007398 99 99 0,000 0,32435441 0,32453049 ! response to other organism GO:0051707 101 100 0,000 0,32704463 0,32704463