pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6902-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cell migration GO:0030334 71 71 9,000 2,722E-11 5,017E-08 ! regulation of locomotion GO:0040012 79 79 9,000 8,164E-11 7,523E-08 ! regulation of cell motion GO:0051270 79 79 9,000 8,164E-11 5,016E-08 ! positive regulation of MAP kinase activity GO:0043406 50 49 7,000 9,292E-10 4,281E-07 ! response to hypoxia GO:0001666 53 53 7,000 1,79E-09 6,596E-07 ! response to oxygen levels GO:0070482 55 54 7,000 2,09E-09 6,42E-07 ! positive regulation of cell migration GO:0030335 36 36 6,000 3,137E-09 8,258E-07 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 8,000 4,502E-09 1,037E-06 ! positive regulation of cell motion GO:0051272 39 39 6,000 5,691E-09 1,165E-06 ! regulation of MAP kinase activity GO:0043405 67 66 7,000 1,086E-08 2,001E-06 ! negative regulation of multicellular organismal process GO:0051241 55 54 6,000 6,069E-08 1,017E-05 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 4,000 6,96E-08 1,069E-05 ! cell junction assembly GO:0034329 18 17 4,000 6,96E-08 9,868E-06 ! regulation of angiogenesis GO:0045765 35 34 5,000 8,511E-08 1,12E-05 ! positive regulation of protein kinase activity GO:0045860 89 86 7,000 9,061E-08 1,113E-05 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 4,000 9,588E-08 1,104E-05 ! positive regulation of transferase activity GO:0051347 91 88 7,000 1,086E-07 1,178E-05 GO:0033674|positive regulation of kinase activity, ! negative regulation of blood coagulation GO:0030195 9 8 3,000 1,312E-07 1,343E-05 ! cell junction organization GO:0034330 23 22 4,000 2,887E-07 2,801E-05 ! regulation of mitotic cell cycle GO:0007346 72 69 6,000 3,424E-07 3,155E-05 ! wound healing GO:0042060 74 70 6,000 3,785E-07 3,322E-05 ! cell-substrate junction assembly GO:0007044 11 10 3,000 3,897E-07 3,264E-05 ! negative regulation of coagulation GO:0050819 11 10 3,000 3,897E-07 3,122E-05 ! regulation of membrane potential GO:0042391 46 46 5,000 5,574E-07 4,28E-05 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 3,000 6,093E-07 4,492E-05 ! positive regulation of cell cycle GO:0045787 29 29 4,000 1,256E-06 8,906E-05 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 3,000 1,307E-06 8,921E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 3,000 1,307E-06 8,602E-05 ! regulation of blood coagulation GO:0030193 15 14 3,000 1,821E-06 1,157E-04 ! wound healing, spreading of epidermal cells GO:0035313 5 5 2,000 2,96E-06 1,819E-04 ! positive regulation of mitosis GO:0045840 16 16 3,000 3,277E-06 1,948E-04 GO:0051785|positive regulation of nuclear division, ! regulation of coagulation GO:0050818 17 16 3,000 3,277E-06 1,887E-04 ! regulation of mitosis GO:0007088 37 36 4,000 3,849E-06 2,149E-04 GO:0051783|regulation of nuclear division, ! cell-matrix adhesion GO:0007160 39 38 4,000 5,072E-06 2,75E-04 ! activation of MAPK activity GO:0000187 39 39 4,000 5,789E-06 3,048E-04 ! focal adhesion formation GO:0048041 7 6 2,000 5,892E-06 3,016E-04 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 5,892E-06 2,935E-04 ! cell-substrate adhesion GO:0031589 43 42 4,000 8,423E-06 4,085E-04 ! DNA integrity checkpoint GO:0031570 21 21 3,000 1,051E-05 4,967E-04 ! regulation of multicellular organism growth GO:0040014 21 21 3,000 1,051E-05 4,843E-04 ! cellular response to hormone stimulus GO:0032870 48 46 4,000 1,33E-05 5,978E-04 ! positive regulation of growth GO:0045927 23 23 3,000 1,54E-05 6,756E-04 ! negative regulation of bone remodeling GO:0046851 8 8 2,000 1,634E-05 7,003E-04 ! positive regulation of endothelial cell migration GO:0010595 8 8 2,000 1,634E-05 6,844E-04 ! plasma membrane fusion GO:0045026 8 8 2,000 1,634E-05 6,692E-04 ! regulation of cell cycle process GO:0010564 50 48 4,000 1,644E-05 6,588E-04 ! heart development GO:0007507 90 87 5,000 2,435E-05 9,548E-04 ! negative regulation of tissue remodeling GO:0034104 9 9 2,000 2,439E-05 9,365E-04 ! defense response to virus GO:0051607 9 9 2,000 2,439E-05 9,174E-04 ! regulation of body fluid levels GO:0050878 55 52 4,000 2,445E-05 9,014E-04 ! negative regulation of cell migration GO:0030336 26 26 3,000 2,56E-05 9,253E-04 ! negative regulation of homeostatic process GO:0032845 10 10 2,000 3,468E-05 1,229E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 3,472E-05 1,207E-03 ! peptidyl-amino acid modification GO:0018193 61 59 4,000 4,546E-05 1,551E-03 ! positive regulation of hormone secretion GO:0046887 11 11 2,000 4,745E-05 1,59E-03 ! negative regulation of angiogenesis GO:0016525 11 11 2,000 4,745E-05 1,562E-03 ! hindbrain development GO:0030902 11 11 2,000 4,745E-05 1,534E-03 ! blood circulation GO:0008015 99 98 5,000 4,797E-05 1,524E-03 GO:0003013|circulatory system process, ! negative regulation of cell motion GO:0051271 31 31 3,000 5,256E-05 1,642E-03 ! response to hormone stimulus GO:0009725 102 100 5,000 5,377E-05 1,652E-03 ! renal system process GO:0003014 12 12 2,000 6,297E-05 1,903E-03 ! positive regulation of multicellular organism growth GO:0040018 12 12 2,000 6,297E-05 1,872E-03 ! regulation of response to external stimulus GO:0032101 65 64 4,000 6,749E-05 1,974E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 7,631E-05 2,197E-03 ! negative regulation of hormone secretion GO:0046888 13 13 2,000 8,147E-05 2,31E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 8,147E-05 2,275E-03 ! regulation of endothelial cell migration GO:0010594 13 13 2,000 8,147E-05 2,241E-03 ! response to cytokine stimulus GO:0034097 13 13 2,000 8,147E-05 2,208E-03 ! positive regulation of organelle organization GO:0010638 36 36 3,000 9,596E-05 2,563E-03 ! coagulation GO:0050817 39 36 3,000 9,596E-05 2,527E-03 GO:0007596|blood coagulation, ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,032E-04 2,679E-03 ! response to retinoic acid GO:0032526 14 14 2,000 1,032E-04 2,641E-03 GO:0033189|response to vitamin A, ! regulation of vasoconstriction GO:0019229 14 14 2,000 1,032E-04 2,605E-03 ! response to vitamin GO:0033273 15 15 2,000 1,284E-04 3,197E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 1,284E-04 3,154E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 1,284E-04 3,113E-03 ! hemostasis GO:0007599 42 39 3,000 1,32E-04 3,159E-03 ! triglyceride metabolic process GO:0006641 16 16 2,000 1,572E-04 3,715E-03 ! cell cycle checkpoint GO:0000075 42 41 3,000 1,609E-04 3,754E-03 ! myelination GO:0042552 17 17 2,000 1,9E-04 4,378E-03 ! glucose transport GO:0015758 17 17 2,000 1,9E-04 4,323E-03 ! response to toxin GO:0009636 18 17 2,000 1,9E-04 4,271E-03 ! MAPKKK cascade GO:0000165 82 81 4,000 2,08E-04 4,618E-03 ! tube development GO:0035295 83 81 4,000 2,08E-04 4,563E-03 ! hexose transport GO:0008645 18 18 2,000 2,269E-04 4,92E-03 GO:0015749|monosaccharide transport, ! neutral lipid metabolic process GO:0006638 18 18 2,000 2,269E-04 4,863E-03 GO:0006639|acylglycerol metabolic process, ! ensheathment of neurons GO:0007272 18 18 2,000 2,269E-04 4,807E-03 GO:0008366|axon ensheathment, ! DNA damage checkpoint GO:0000077 19 19 2,000 2,682E-04 5,617E-03 ! regulation of striated muscle tissue development GO:0016202 20 19 2,000 2,682E-04 5,554E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 2,682E-04 5,492E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 2,000 2,682E-04 5,432E-03 ! regulation of muscle development GO:0048634 21 20 2,000 3,14E-04 6,29E-03 ! organic ether metabolic process GO:0018904 20 20 2,000 3,14E-04 6,223E-03 GO:0006662|glycerol ether metabolic process, ! nucleus organization GO:0006997 20 20 2,000 3,14E-04 6,157E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 3,14E-04 6,092E-03 ! response to nutrient GO:0007584 49 49 3,000 3,235E-04 6,21E-03 ! mitotic sister chromatid segregation GO:0000070 21 21 2,000 3,646E-04 6,927E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 3,646E-04 6,857E-03 ! regulation of action potential in neuron GO:0019228 21 21 2,000 3,646E-04 6,787E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 3,646E-04 6,719E-03 ! sister chromatid segregation GO:0000819 22 22 2,000 4,201E-04 7,667E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 4,509E-04 8,147E-03 ! metencephalon development GO:0022037 5 5 1,000 4,509E-04 8,067E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 1,000 4,509E-04 7,99E-03 GO:0010469|regulation of receptor activity, ! mRNA stabilization GO:0048255 5 5 1,000 4,509E-04 7,914E-03 GO:0043489|RNA stabilization, ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 4,509E-04 7,839E-03 ! memory GO:0007613 5 5 1,000 4,509E-04 7,766E-03 ! middle ear morphogenesis GO:0042474 5 5 1,000 4,509E-04 7,694E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 4,509E-04 7,623E-03 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 1,000 4,509E-04 7,554E-03 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! muscle cell migration GO:0014812 5 5 1,000 4,509E-04 7,486E-03 ! phasic smooth muscle contraction GO:0014821 5 5 1,000 4,509E-04 7,419E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,509E-04 7,354E-03 ! maintenance of protein location in nucleus GO:0051457 5 5 1,000 4,509E-04 7,289E-03 ! fear response GO:0042596 5 5 1,000 4,509E-04 7,226E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 4,509E-04 7,163E-03 ! response to UV-B GO:0010224 5 5 1,000 4,509E-04 7,102E-03 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 4,509E-04 7,042E-03 ! cellular pigmentation GO:0033059 5 5 1,000 4,509E-04 6,983E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 4,509E-04 6,925E-03 ! regulation of DNA replication initiation GO:0030174 5 5 1,000 4,509E-04 6,867E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,509E-04 6,811E-03 ! oocyte differentiation GO:0009994 5 5 1,000 4,509E-04 6,756E-03 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 4,509E-04 6,701E-03 ! spleen development GO:0048536 5 5 1,000 4,509E-04 6,648E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 4,509E-04 6,595E-03 ! positive regulation of smooth muscle contraction GO:0045987 5 5 1,000 4,509E-04 6,543E-03 ! response to nicotine GO:0035094 5 5 1,000 4,509E-04 6,492E-03 ! regulation of cell growth GO:0001558 97 96 4,000 4,597E-04 6,567E-03 ! protein amino acid dephosphorylation GO:0006470 55 54 3,000 4,709E-04 6,676E-03 ! regulation of hormone secretion GO:0046883 23 23 2,000 4,809E-04 6,765E-03 ! calcium-mediated signaling GO:0019722 23 23 2,000 4,809E-04 6,714E-03 ! mitochondrial transport GO:0006839 24 24 2,000 5,469E-04 7,579E-03 ! regulation of action potential GO:0001508 24 24 2,000 5,469E-04 7,522E-03 ! glucose homeostasis GO:0042593 24 24 2,000 5,469E-04 7,466E-03 GO:0033500|carbohydrate homeostasis, ! negative regulation of secretion GO:0051048 26 25 2,000 6,185E-04 8,382E-03 ! dephosphorylation GO:0016311 60 59 3,000 6,61E-04 8,892E-03 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 6,734E-04 8,993E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 6,734E-04 8,928E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 6,734E-04 8,864E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 6,734E-04 8,801E-03 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 1,000 6,734E-04 8,739E-03 ! positive regulation of heart contraction GO:0045823 6 6 1,000 6,734E-04 8,678E-03 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 6,734E-04 8,618E-03 ! inositol phosphate-mediated signaling GO:0048016 6 6 1,000 6,734E-04 8,559E-03 ! vascular smooth muscle contraction GO:0014829 6 6 1,000 6,734E-04 8,5E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 6,734E-04 8,442E-03 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 1,000 6,734E-04 8,385E-03 ! regulation of heart rate GO:0002027 6 6 1,000 6,734E-04 8,329E-03 ! regulation of vascular permeability GO:0043114 6 6 1,000 6,734E-04 8,273E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 6,734E-04 8,219E-03 ! negative regulation of ossification GO:0030279 6 6 1,000 6,734E-04 8,164E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 6,734E-04 8,111E-03 ! purine base biosynthetic process GO:0009113 6 6 1,000 6,734E-04 8,058E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 6,734E-04 8,006E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 6,734E-04 7,955E-03 ! renal water homeostasis GO:0003091 6 6 1,000 6,734E-04 7,904E-03 ! thymus development GO:0048538 6 6 1,000 6,734E-04 7,854E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 6,734E-04 7,805E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 6,734E-04 7,756E-03 ! localization within membrane GO:0051668 6 6 1,000 6,734E-04 7,708E-03 ! pigment metabolic process GO:0042440 26 26 2,000 6,959E-04 7,917E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 6,959E-04 7,868E-03 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 7,504E-04 8,432E-03 ! mesenchymal cell development GO:0014031 29 27 2,000 7,791E-04 8,702E-03 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! axonogenesis GO:0007409 66 62 3,000 7,981E-04 8,861E-03 ! carbohydrate transport GO:0008643 28 28 2,000 8,684E-04 9,584E-03 ! angiogenesis GO:0001525 65 64 3,000 9E-04 9,873E-03 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 9,386E-04 0,01023567 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 9,386E-04 0,01017546 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 9,386E-04 0,01011595 ! hair follicle morphogenesis GO:0031069 7 7 1,000 9,386E-04 0,01005714 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 9,386E-04 9,999E-03 ! digestive system development GO:0055123 7 7 1,000 9,386E-04 9,942E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 9,386E-04 9,885E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 9,386E-04 9,829E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 9,386E-04 9,773E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 1,000 9,386E-04 9,718E-03 ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 9,386E-04 9,664E-03 ! cranial nerve development GO:0021545 7 7 1,000 9,386E-04 9,61E-03 ! autonomic nervous system development GO:0048483 7 7 1,000 9,386E-04 9,557E-03 ! platelet activation GO:0030168 8 7 1,000 9,386E-04 9,505E-03 ! response to gamma radiation GO:0010332 8 7 1,000 9,386E-04 9,453E-03 ! multicellular organismal water homeostasis GO:0050891 7 7 1,000 9,386E-04 9,401E-03 ! cAMP biosynthetic process GO:0006171 7 7 1,000 9,386E-04 9,35E-03 ! regulation of mRNA stability GO:0043488 7 7 1,000 9,386E-04 9,3E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 9,386E-04 9,25E-03 ! positive regulation of cellular component organization GO:0051130 65 65 3,000 9,543E-04 9,355E-03 ! regulation of hormone levels GO:0010817 66 65 3,000 9,543E-04 9,305E-03 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 9,64E-04 9,351E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 9,64E-04 9,302E-03 ! response to UV GO:0009411 29 29 2,000 9,64E-04 9,254E-03 ! response to reactive oxygen species GO:0000302 31 30 2,000 1,066E-03 0,01017974 ! activation of phospholipase C activity GO:0007202 30 30 2,000 1,066E-03 0,01012727 GO:0010863|positive regulation of phospholipase C activity, ! vascular process in circulatory system GO:0003018 31 30 2,000 1,066E-03 0,01007533 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 3,000 1,07E-03 0,01005764 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! response to radiation GO:0009314 70 68 3,000 1,131E-03 0,01057914 ! regulation of cell size GO:0008361 68 68 3,000 1,131E-03 0,01052571 ! membrane fusion GO:0006944 31 31 2,000 1,175E-03 0,01087846 ! positive regulation of phospholipase activity GO:0010518 31 31 2,000 1,175E-03 0,01082407 ! regulation of DNA replication GO:0006275 32 31 2,000 1,175E-03 0,01077022 ! regulation of heart contraction GO:0008016 31 31 2,000 1,175E-03 0,0107169 ! regionalization GO:0003002 70 69 3,000 1,194E-03 0,01084406 ! response to nutrient levels GO:0031667 69 69 3,000 1,194E-03 0,0107909 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,246E-03 0,01120195 ! T cell selection GO:0045058 8 8 1,000 1,246E-03 0,01114757 ! phosphagen metabolic process GO:0006599 8 8 1,000 1,246E-03 0,01109371 GO:0006600|creatine metabolic process, ! cell-cell junction assembly GO:0007043 8 8 1,000 1,246E-03 0,01104038 ! sex determination GO:0007530 8 8 1,000 1,246E-03 0,01098755 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,246E-03 0,01093523 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,246E-03 0,01088341 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,246E-03 0,01083207 ! vasoconstriction GO:0042310 8 8 1,000 1,246E-03 0,01078122 ! T cell homeostasis GO:0043029 8 8 1,000 1,246E-03 0,01073084 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,246E-03 0,01068093 ! water homeostasis GO:0030104 8 8 1,000 1,246E-03 0,01063148 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,246E-03 0,01058248 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 1,000 1,246E-03 0,01053394 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,246E-03 0,01048584 ! regulation of RNA stability GO:0043487 8 8 1,000 1,246E-03 0,01043818 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,246E-03 0,01039095 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,246E-03 0,01034414 ! peptide hormone secretion GO:0030072 8 8 1,000 1,246E-03 0,01029775 ! cell part morphogenesis GO:0032990 75 70 3,000 1,261E-03 0,01037122 ! negative regulation of cell growth GO:0030308 32 32 2,000 1,29E-03 0,01056607 ! regulation of phospholipase activity GO:0010517 32 32 2,000 1,29E-03 0,01051932 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 1,29E-03 0,01047298 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 1,29E-03 0,01042704 ! positive regulation of lipase activity GO:0060193 32 32 2,000 1,29E-03 0,01038151 ! response to extracellular stimulus GO:0009991 72 72 3,000 1,4E-03 0,01122095 ! negative regulation of cell size GO:0045792 33 33 2,000 1,412E-03 0,0112668 ! activation of protein kinase activity GO:0032147 35 33 2,000 1,412E-03 0,01121824 ! regulation of bone remodeling GO:0046850 34 34 2,000 1,541E-03 0,01219265 ! ear development GO:0043583 34 34 2,000 1,541E-03 0,01214055 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 2,000 1,541E-03 0,01208889 ! secondary metabolic process GO:0019748 34 34 2,000 1,541E-03 0,01203766 ! positive regulation of cell size GO:0045793 9 9 1,000 1,595E-03 0,01240367 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,595E-03 0,01235155 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,595E-03 0,01229987 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 1,000 1,595E-03 0,01224862 ! response to alkaloid GO:0043279 10 9 1,000 1,595E-03 0,0121978 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 1,000 1,595E-03 0,01214739 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,595E-03 0,0120974 ! response to ethanol GO:0045471 9 9 1,000 1,595E-03 0,01204782 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,595E-03 0,01199865 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,595E-03 0,01194987 ! glutamine metabolic process GO:0006541 9 9 1,000 1,595E-03 0,01190149 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 1,595E-03 0,0118535 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,595E-03 0,0118059 GO:0060675|ureteric bud morphogenesis, ! peptide secretion GO:0002790 9 9 1,000 1,595E-03 0,01175868 ! DNA replication initiation GO:0006270 9 9 1,000 1,595E-03 0,01171183 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,595E-03 0,01166535 ! histone acetylation GO:0016573 9 9 1,000 1,595E-03 0,01161924 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 1,595E-03 0,0115735 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,595E-03 0,01152811 ! purine base metabolic process GO:0006144 9 9 1,000 1,595E-03 0,01148308 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,595E-03 0,0114384 ! multicellular organism reproduction GO:0032504 36 35 2,000 1,678E-03 0,01198608 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 2,000 1,678E-03 0,0119398 ! regulation of tissue remodeling GO:0034103 35 35 2,000 1,678E-03 0,01189388 ! positive regulation of multicellular organismal process GO:0051240 76 76 3,000 1,712E-03 0,01208806 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 1,797E-03 0,01263866 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 2,000 1,822E-03 0,01276601 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 1,822E-03 0,01271765 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 2,000 1,822E-03 0,01266966 ! regulation of lipase activity GO:0060191 36 36 2,000 1,822E-03 0,01262203 ! regulation of protein modification process GO:0031399 79 78 3,000 1,884E-03 0,01300744 ! lung development GO:0030324 38 37 2,000 1,973E-03 0,01356827 ! negative regulation of growth GO:0045926 37 37 2,000 1,973E-03 0,01351783 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 1,973E-03 0,01346777 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,985E-03 0,0135004 ! hormone secretion GO:0046879 10 10 1,000 1,985E-03 0,01345076 ! cAMP metabolic process GO:0046058 10 10 1,000 1,985E-03 0,01340149 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,985E-03 0,01335258 ! regulation of survival gene product expression GO:0045884 10 10 1,000 1,985E-03 0,01330403 ! epidermis morphogenesis GO:0048730 10 10 1,000 1,985E-03 0,01325583 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 1,985E-03 0,01320797 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 1,985E-03 0,01316046 ! neuromuscular junction development GO:0007528 10 10 1,000 1,985E-03 0,01311329 ! regulation of protein binding GO:0043393 11 10 1,000 1,985E-03 0,01306646 ! gland morphogenesis GO:0022612 10 10 1,000 1,985E-03 0,01301996 ! lymphocyte homeostasis GO:0002260 10 10 1,000 1,985E-03 0,01297379 ! nerve development GO:0021675 10 10 1,000 1,985E-03 0,01292794 ! gut development GO:0048565 10 10 1,000 1,985E-03 0,01288242 ! neuron projection development GO:0031175 85 80 3,000 2,069E-03 0,01337756 ! positive regulation of secretion GO:0051047 39 38 2,000 2,132E-03 0,01373837 ! chromosome segregation GO:0007059 38 38 2,000 2,132E-03 0,0136905 ! regulation of homeostatic process GO:0032844 38 38 2,000 2,132E-03 0,01364296 ! respiratory tube development GO:0030323 40 39 2,000 2,299E-03 0,01465858 ! nucleoside monophosphate metabolic process GO:0009123 39 39 2,000 2,299E-03 0,01460804 ! respiratory system development GO:0060541 40 39 2,000 2,299E-03 0,01455784 ! blood vessel morphogenesis GO:0048514 84 83 3,000 2,368E-03 0,01494583 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 2,416E-03 0,01519521 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 2,416E-03 0,01514353 ! signal complex assembly GO:0007172 11 11 1,000 2,416E-03 0,01509219 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,416E-03 0,01504121 ! regulation of viral genome replication GO:0045069 11 11 1,000 2,416E-03 0,01499056 ! smooth muscle contraction GO:0006939 11 11 1,000 2,416E-03 0,01494026 ! apoptotic nuclear changes GO:0030262 11 11 1,000 2,416E-03 0,01489029 ! body fluid secretion GO:0007589 11 11 1,000 2,416E-03 0,01484066 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,416E-03 0,01479135 ! interaction with host GO:0051701 11 11 1,000 2,416E-03 0,01474237 ! membrane depolarization GO:0051899 11 11 1,000 2,416E-03 0,01469372 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,416E-03 0,01464538 ! oogenesis GO:0048477 11 11 1,000 2,416E-03 0,01459737 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,416E-03 0,01454966 GO:0006109|regulation of carbohydrate metabolic process, ! endocrine process GO:0050886 11 11 1,000 2,416E-03 0,01450227 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,416E-03 0,01445518 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 2,886E-03 0,01721497 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 2,886E-03 0,01715944 ! heterophilic cell adhesion GO:0007157 12 12 1,000 2,886E-03 0,01710426 ! C21-steroid hormone metabolic process GO:0008207 13 12 1,000 2,886E-03 0,01704944 ! regulation of muscle cell differentiation GO:0051147 13 12 1,000 2,886E-03 0,01699497 ! mitotic chromosome condensation GO:0007076 12 12 1,000 2,886E-03 0,01694085 ! male gonad development GO:0008584 12 12 1,000 2,886E-03 0,01688707 ! regulation of insulin secretion GO:0050796 12 12 1,000 2,886E-03 0,01683363 ! regulation of chromosome organization GO:0033044 12 12 1,000 2,886E-03 0,01678052 ! somitogenesis GO:0001756 13 12 1,000 2,886E-03 0,01672775 ! hormone transport GO:0009914 12 12 1,000 2,886E-03 0,01667532 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 2,886E-03 0,01662321 ! negative regulation of translation GO:0017148 12 12 1,000 2,886E-03 0,01657142 ! mitochondrion organization GO:0007005 44 43 2,000 3,045E-03 0,01742998 ! brain development GO:0007420 91 90 3,000 3,18E-03 0,01814465 ! positive regulation of DNA replication GO:0045740 14 13 1,000 3,396E-03 0,01931881 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 3,396E-03 0,01925937 ! regeneration GO:0031099 13 13 1,000 3,396E-03 0,01920029 ! post-embryonic development GO:0009791 14 13 1,000 3,396E-03 0,01914157 ! patterning of blood vessels GO:0001569 13 13 1,000 3,396E-03 0,01908322 ! vasculogenesis GO:0001570 13 13 1,000 3,396E-03 0,01902521 ! negative regulation of DNA replication GO:0008156 13 13 1,000 3,396E-03 0,01896756 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 3,396E-03 0,01891026 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 3,396E-03 0,0188533 ! ureteric bud development GO:0001657 13 13 1,000 3,396E-03 0,01879668 ! cell aging GO:0007569 13 13 1,000 3,396E-03 0,0187404 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 3,396E-03 0,01868446 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 1,000 3,396E-03 0,01862885 ! regulation of viral reproduction GO:0050792 13 13 1,000 3,396E-03 0,01857358 ! nucleobase metabolic process GO:0009112 13 13 1,000 3,396E-03 0,01851862 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 1,000 3,396E-03 0,018464 ! positive regulation of locomotion GO:0040017 13 13 1,000 3,396E-03 0,01840969 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neutrophil chemotaxis GO:0030593 14 13 1,000 3,396E-03 0,0183557 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,396E-03 0,01830203 ! cell-cell junction organization GO:0045216 13 13 1,000 3,396E-03 0,01824867 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 3,396E-03 0,01819562 GO:0001952|regulation of cell-matrix adhesion, ! tissue homeostasis GO:0001894 13 13 1,000 3,396E-03 0,01814288 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 3,396E-03 0,01809045 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 3,468E-03 0,01842103 ! tube morphogenesis GO:0035239 47 46 2,000 3,693E-03 0,01955615 ! regulation of response to stress GO:0080134 97 94 3,000 3,72E-03 0,01964705 ! blood vessel development GO:0001568 95 94 3,000 3,72E-03 0,01959091 ! pattern specification process GO:0007389 96 94 3,000 3,72E-03 0,0195351 ! protein amino acid acylation GO:0043543 14 14 1,000 3,945E-03 0,02065572 ! hair cycle GO:0042633 14 14 1,000 3,945E-03 0,02059721 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! multicellular organismal response to stress GO:0033555 14 14 1,000 3,945E-03 0,02053902 ! peptide transport GO:0015833 14 14 1,000 3,945E-03 0,02048117 ! regulation of behavior GO:0050795 14 14 1,000 3,945E-03 0,02042364 ! response to organic cyclic substance GO:0014070 15 14 1,000 3,945E-03 0,02036643 ! vasculature development GO:0001944 97 96 3,000 4,013E-03 0,02065808 ! actin filament organization GO:0007015 50 48 2,000 4,167E-03 0,02139456 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 4,32E-03 0,02211786 ! regulation of system process GO:0044057 98 98 3,000 4,32E-03 0,02205659 ! ossification GO:0001503 50 49 2,000 4,418E-03 0,0224936 GO:0060348|bone development, ! gland development GO:0048732 51 49 2,000 4,418E-03 0,02243163 ! skeletal muscle tissue development GO:0007519 50 49 2,000 4,418E-03 0,02237001 GO:0060538|skeletal muscle organ development, ! ovarian follicle development GO:0001541 15 15 1,000 4,532E-03 0,02288494 ! regulation of smooth muscle contraction GO:0006940 15 15 1,000 4,532E-03 0,02282241 ! chromosome condensation GO:0030261 15 15 1,000 4,532E-03 0,02276023 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 1,000 4,532E-03 0,02269838 ! leukocyte homeostasis GO:0001776 15 15 1,000 4,532E-03 0,02263686 ! negative regulation of cell activation GO:0050866 15 15 1,000 4,532E-03 0,02257568 ! muscle organ development GO:0007517 102 100 3,000 4,644E-03 0,0230674 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 4,678E-03 0,02317547 ! negative regulation of transport GO:0051051 51 50 2,000 4,678E-03 0,02311334 ! T cell activation GO:0042110 51 50 2,000 4,678E-03 0,02305154 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 4,678E-03 0,02299007 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 4,947E-03 0,02424627 GO:0051325|interphase, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 5,157E-03 0,02521191 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 5,157E-03 0,02514521 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 5,157E-03 0,02507887 ! positive regulation of cytoskeleton organization GO:0051495 16 16 1,000 5,157E-03 0,02501287 ! segmentation GO:0035282 17 16 1,000 5,157E-03 0,02494722 ! positive regulation of cell development GO:0010720 16 16 1,000 5,157E-03 0,02488191 ! lymphocyte proliferation GO:0046651 16 16 1,000 5,157E-03 0,02481695 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 5,157E-03 0,02475232 ! positive regulation of catabolic process GO:0009896 16 16 1,000 5,157E-03 0,02468803 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 5,157E-03 0,02462407 GO:0043507|positive regulation of JUN kinase activity, ! response to light stimulus GO:0009416 53 52 2,000 5,225E-03 0,02488066 ! response to virus GO:0009615 54 54 2,000 5,808E-03 0,02758911 ! hormone metabolic process GO:0042445 55 54 2,000 5,808E-03 0,02751819 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,82E-03 0,02750132 ! leukocyte adhesion GO:0007159 17 17 1,000 5,82E-03 0,02743099 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 5,82E-03 0,02736101 ! tissue remodeling GO:0048771 17 17 1,000 5,82E-03 0,02729139 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 5,82E-03 0,02722212 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 5,82E-03 0,0271532 ! neural crest cell development GO:0014032 19 17 1,000 5,82E-03 0,02708464 GO:0014033|neural crest cell differentiation, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 5,82E-03 0,02701641 ! pigmentation GO:0043473 17 17 1,000 5,82E-03 0,02694853 ! regulation of cell adhesion GO:0030155 56 55 2,000 6,114E-03 0,02824165 ! reproductive developmental process GO:0003006 56 56 2,000 6,43E-03 0,02962442 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 6,519E-03 0,02995992 ! meiosis I GO:0007127 18 18 1,000 6,519E-03 0,02988539 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 6,519E-03 0,02981123 ! mononuclear cell proliferation GO:0032943 18 18 1,000 6,519E-03 0,02973744 GO:0070661|leukocyte proliferation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 6,519E-03 0,02966401 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 6,519E-03 0,02959095 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! B cell differentiation GO:0030183 18 18 1,000 6,519E-03 0,02951825 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 6,519E-03 0,0294459 ! regulation of binding GO:0051098 60 57 2,000 6,755E-03 0,03043708 ! regulation of protein localization GO:0032880 58 57 2,000 6,755E-03 0,03036284 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 7,254E-03 0,03252842 ! regulation of pH GO:0006885 19 19 1,000 7,254E-03 0,03244946 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 7,254E-03 0,03237089 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 7,254E-03 0,0322927 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 7,254E-03 0,03221489 ! metanephros development GO:0001656 19 19 1,000 7,254E-03 0,03213745 ! cellular response to oxidative stress GO:0034599 19 19 1,000 7,254E-03 0,03206038 ! peripheral nervous system development GO:0007422 19 19 1,000 7,254E-03 0,03198368 ! regulation of protein stability GO:0031647 19 19 1,000 7,254E-03 0,03190735 ! hormone biosynthetic process GO:0042446 19 19 1,000 7,254E-03 0,03183138 ! regulation of cell shape GO:0008360 21 19 1,000 7,254E-03 0,03175577 ! response to heat GO:0009408 19 19 1,000 7,254E-03 0,03168052 ! regulation of cell development GO:0060284 60 59 2,000 7,434E-03 0,03238822 ! immune effector process GO:0002252 59 59 2,000 7,434E-03 0,03231183 ! cyclic nucleotide metabolic process GO:0009187 20 20 1,000 8,025E-03 0,0348008 ! chromatin remodeling GO:0006338 20 20 1,000 8,025E-03 0,03471911 ! female gamete generation GO:0007292 20 20 1,000 8,025E-03 0,0346378 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 8,025E-03 0,03455687 ! single fertilization GO:0007338 21 20 1,000 8,025E-03 0,03447632 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 8,526E-03 0,03654168 GO:0060429|epithelium development, ! mammary gland development GO:0030879 23 21 1,000 8,832E-03 0,03776447 ! receptor-mediated endocytosis GO:0006898 21 21 1,000 8,832E-03 0,03767706 ! ear morphogenesis GO:0042471 21 21 1,000 8,832E-03 0,03759004 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 8,832E-03 0,03750343 ! regulation of secretion GO:0051046 65 63 2,000 8,91E-03 0,0377481 ! glycerolipid metabolic process GO:0046486 65 64 2,000 9,304E-03 0,03932663 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 9,673E-03 0,04079337 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 9,673E-03 0,04070024 ! cellular amide metabolic process GO:0043603 22 22 1,000 9,673E-03 0,04060753 ! hormone-mediated signaling GO:0009755 22 22 1,000 9,673E-03 0,04051524 ! embryonic skeletal system development GO:0048706 22 22 1,000 9,673E-03 0,04042337 ! maintenance of protein location in cell GO:0032507 23 22 1,000 9,673E-03 0,04033191 ! ovulation cycle process GO:0022602 22 22 1,000 9,673E-03 0,04024087 ! spindle organization GO:0007051 22 22 1,000 9,673E-03 0,04015024 ! pigment biosynthetic process GO:0046148 22 22 1,000 9,673E-03 0,04006001 ! cell chemotaxis GO:0060326 23 22 1,000 9,673E-03 0,03997019 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 1,000 9,673E-03 0,03988077 ! male sex differentiation GO:0046661 22 22 1,000 9,673E-03 0,03979175 ! cytokinesis GO:0000910 23 22 1,000 9,673E-03 0,03970313 ! striated muscle tissue development GO:0014706 69 67 2,000 0,01054597 0,04319162 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,01054807 0,0431044 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,01054807 0,04300904 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 1,000 0,01054807 0,04291409 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01054807 0,04281957 ! female gonad development GO:0008585 23 23 1,000 0,01054807 0,04272546 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,01054807 0,04263177 ! regulation of JNK cascade GO:0046328 25 23 1,000 0,01054807 0,04253848 ! cell projection assembly GO:0030031 25 23 1,000 0,01054807 0,0424456 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,01145726 0,04600377 ! T cell differentiation GO:0030217 24 24 1,000 0,01145726 0,04590376 ! ovulation cycle GO:0042698 24 24 1,000 0,01145726 0,04580419 ! fertilization GO:0009566 25 24 1,000 0,01145726 0,04570505 ! maintenance of protein location GO:0045185 25 24 1,000 0,01145726 0,04560633 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01145726 0,04550804 ! positive regulation of transport GO:0051050 71 70 2,000 0,01188048 0,04708759 ! growth GO:0040007 70 70 2,000 0,01188048 0,04698655 ! muscle tissue development GO:0060537 72 70 2,000 0,01188048 0,04688593 ! calcium ion homeostasis GO:0055074 71 71 2,000 0,01234598 0,0486189 GO:0006874|cellular calcium ion homeostasis, ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01239976 0,04872656 ! cellular component disassembly GO:0022411 26 25 1,000 0,01239976 0,04862288 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01239976 0,04851965 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01239976 0,04841685 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01239976 0,04831449 ! excretion GO:0007588 25 25 1,000 0,01239976 0,04821256 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01239976 0,04811106 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,01239976 0,04800999 ! heart morphogenesis GO:0003007 25 25 1,000 0,01239976 0,04790934 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01239976 0,04780911 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01239976 0,0477093 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,01282188 0,04923068 ! sensory organ development GO:0007423 72 72 2,000 0,01282188 0,04912833 ! positive regulation of binding GO:0051099 27 26 1,000 0,01337508 0,05114165 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01337508 0,05103577 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01337508 0,05093032 ! germ cell development GO:0007281 27 26 1,000 0,01337508 0,05082531 ! regulation of blood vessel size GO:0050880 27 26 1,000 0,01337508 0,05072074 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 1,000 0,01337508 0,05061659 ! synapse organization GO:0050808 26 26 1,000 0,01337508 0,05051286 ! response to oxidative stress GO:0006979 76 75 2,000 0,01431231 0,05394189 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01438276 0,05409679 ! learning or memory GO:0007611 28 27 1,000 0,01438276 0,05398661 ! peptide metabolic process GO:0006518 29 27 1,000 0,01438276 0,05387688 ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 0,01438276 0,0537676 ! cellular metal ion homeostasis GO:0006875 77 77 2,000 0,01535852 0,05729908 ! regulation of muscle contraction GO:0006937 28 28 1,000 0,01542232 0,05742089 ! histone modification GO:0016570 28 28 1,000 0,01542232 0,05730512 ! developmental growth GO:0048589 28 28 1,000 0,01542232 0,05718982 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01542232 0,05707498 ! cartilage development GO:0051216 29 28 1,000 0,01542232 0,0569606 ! metal ion homeostasis GO:0055065 78 78 2,000 0,01589748 0,05859811 ! viral reproductive process GO:0022415 29 29 1,000 0,01649331 0,06067299 ! leukocyte migration GO:0050900 30 29 1,000 0,01649331 0,06055212 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01649331 0,06043174 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01649331 0,06031184 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01649331 0,06019241 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! lymphocyte activation GO:0046649 82 81 2,000 0,01757809 0,06402453 ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01759526 0,06396066 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,01759526 0,06383476 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,01759526 0,06370935 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01759526 0,06358443 ! regulation of ossification GO:0030278 30 30 1,000 0,01759526 0,06345999 ! vesicle organization GO:0016050 30 30 1,000 0,01759526 0,06333605 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01759526 0,06321259 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01872771 0,06715015 ! B cell activation GO:0042113 31 31 1,000 0,01872771 0,06701976 ! aging GO:0007568 32 31 1,000 0,01872771 0,06688988 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01872771 0,0667605 ! muscle fiber development GO:0048747 32 32 1,000 0,01989023 0,07076776 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01989023 0,0706314 ! kidney development GO:0001822 32 32 1,000 0,01989023 0,07049557 ! maintenance of location GO:0051235 33 32 1,000 0,01989023 0,07036026 ! regulation of cellular localization GO:0060341 86 85 2,000 0,01996824 0,0705009 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02108237 0,07429216 ! amino acid transport GO:0006865 33 33 1,000 0,02108237 0,07415038 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02108237 0,07400914 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02108237 0,07386844 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,02108237 0,07372827 ! purine nucleotide biosynthetic process GO:0006164 88 88 2,000 0,02187333 0,07634952 ! response to metal ion GO:0010038 34 34 1,000 0,02230367 0,07770448 ! viral reproduction GO:0016032 34 34 1,000 0,02230367 0,07755787 ! chemotaxis GO:0006935 90 89 2,000 0,02252982 0,07819673 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 2,000 0,02252982 0,07804975 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,02355372 0,08144372 ! mesoderm development GO:0007498 35 35 1,000 0,02355372 0,0812912 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02355372 0,08113926 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02355372 0,08098788 ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,02387504 0,08193984 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 2,000 0,02387504 0,08178753 ! response to inorganic substance GO:0010035 36 36 1,000 0,02483207 0,08490817 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02483207 0,08475093 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,02483207 0,08459428 ! gonad development GO:0008406 36 36 1,000 0,02483207 0,0844382 ! tissue morphogenesis GO:0048729 94 93 2,000 0,02526322 0,08574607 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,0261383 0,0885531 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 0,0261383 0,08839062 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 1,000 0,0261383 0,08822873 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,0261383 0,08806744 ! adaptive immune response GO:0002250 37 37 1,000 0,0261383 0,08790673 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,02747199 0,09222381 ! urogenital system development GO:0001655 38 38 1,000 0,02747199 0,09205613 ! meiotic cell cycle GO:0051321 38 38 1,000 0,02747199 0,09188906 ! axon guidance GO:0007411 39 38 1,000 0,02747199 0,09172259 ! regulation of neurological system process GO:0031644 38 38 1,000 0,02747199 0,09155673 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02883271 0,0959182 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,02883271 0,09574538 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,02883271 0,09557318 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,02883271 0,09540159 ! protein oligomerization GO:0051259 39 39 1,000 0,02883271 0,09523062 ! endocytosis GO:0006897 99 98 2,000 0,0289215 0,09535299 GO:0010324|membrane invagination, ! anti-apoptosis GO:0006916 100 99 2,000 0,0296853 0,09769643 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,03022006 0,09927908 ! DNA catabolic process GO:0006308 41 40 1,000 0,03022006 0,09910243 ! organelle localization GO:0051640 41 40 1,000 0,03022006 0,0989264 ! response to other organism GO:0051707 101 100 2,000 0,03045978 0,09953437 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03163361 0,10318717 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 1,000 0,03163361 0,10300486 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,03307298 0,10750175 ! cytosolic calcium ion homeostasis GO:0051480 42 42 1,000 0,03307298 0,10731249 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,03307298 0,10712389 ! response to protein stimulus GO:0051789 42 42 1,000 0,03307298 0,10693595 ! forebrain development GO:0030900 43 42 1,000 0,03307298 0,10674868 ! rRNA transcription GO:0009303 5 5 0,000 0,03370314 0,10859246 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03370314 0,10840294 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03370314 0,10821409 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03370314 0,10802589 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03370314 0,10783834 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03370314 0,10765145 ! reproductive cellular process GO:0048610 5 5 0,000 0,03370314 0,1074652 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03370314 0,1072796 ! prostate gland development GO:0030850 5 5 0,000 0,03370314 0,10709463 ! water transport GO:0006833 5 5 0,000 0,03370314 0,1069103 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03370314 0,10672661 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03370314 0,10654354 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03370314 0,10636111 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03370314 0,10617929 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03370314 0,1059981 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03370314 0,10581752 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03370314 0,10563756 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03370314 0,10545821 ! filopodium assembly GO:0046847 7 5 0,000 0,03370314 0,10527947 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03370314 0,10510133 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03370314 0,10492379 ! GTP metabolic process GO:0046039 5 5 0,000 0,03370314 0,10474686 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03370314 0,10457051 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03370314 0,10439477 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03370314 0,10421961 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03370314 0,10404503 ! social behavior GO:0035176 5 5 0,000 0,03370314 0,10387105 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03370314 0,10369764 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03370314 0,10352481 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03370314 0,10335256 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03370314 0,10318087 ! response to lipid GO:0033993 5 5 0,000 0,03370314 0,10300976 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03370314 0,10283921 ! hippocampus development GO:0021766 6 5 0,000 0,03370314 0,10266923 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03370314 0,10249981 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03370314 0,10233095 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03370314 0,10216264 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03370314 0,10199489 ! heart looping GO:0001947 5 5 0,000 0,03370314 0,10182768 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03370314 0,10166102 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03370314 0,10149491 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03370314 0,10132934 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03370314 0,10116431 ! pH reduction GO:0045851 5 5 0,000 0,03370314 0,10099981 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03370314 0,10083585 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03370314 0,10067242 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03370314 0,10050952 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03370314 0,10034715 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03370314 0,1001853 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03370314 0,10002397 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03370314 0,09986316 ! adrenal gland development GO:0030325 5 5 0,000 0,03370314 0,09970287 ! melanocyte differentiation GO:0030318 5 5 0,000 0,03370314 0,09954309 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03370314 0,09938382 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03370314 0,09922506 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03370314 0,0990668 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03370314 0,09890905 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03370314 0,09875181 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03370314 0,09859506 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03370314 0,0984388 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03370314 0,09828305 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03370314 0,09812778 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03370314 0,09797301 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03370314 0,09781872 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03370314 0,09766491 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03370314 0,09751159 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03370314 0,09735876 ! response to ATP GO:0033198 5 5 0,000 0,03370314 0,09720639 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03370314 0,09705451 ! regulation of appetite GO:0032098 5 5 0,000 0,03370314 0,0969031 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03370314 0,09675216 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03370314 0,09660169 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03370314 0,09645169 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03370314 0,09630215 ! receptor clustering GO:0043113 5 5 0,000 0,03370314 0,09615307 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03370314 0,09600446 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03370314 0,09585631 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03370314 0,09570861 ! retinol metabolic process GO:0042572 5 5 0,000 0,03370314 0,09556136 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03370314 0,09541457 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03370314 0,09526823 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03370314 0,09512234 ! parturition GO:0007567 5 5 0,000 0,03370314 0,09497689 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03370314 0,09483189 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03370314 0,09468733 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03370314 0,09454321 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03370314 0,09439952 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03370314 0,09425628 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03370314 0,09411346 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03370314 0,09397108 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03370314 0,09382913 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03370314 0,09368761 ! interaction with symbiont GO:0051702 5 5 0,000 0,03370314 0,09354651 ! cellular extravasation GO:0045123 5 5 0,000 0,03370314 0,09340584 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03370314 0,09326559 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03370314 0,09312577 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03370314 0,09298636 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03370314 0,09284736 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03370314 0,09270878 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03370314 0,09257062 ! response to amine stimulus GO:0014075 5 5 0,000 0,03370314 0,09243287 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03370314 0,09229552 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03370314 0,09215858 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03370314 0,09202205 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03370314 0,09188593 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03370314 0,0917502 ! neuron recognition GO:0008038 5 5 0,000 0,03370314 0,09161488 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03370314 0,09147995 ! decidualization GO:0046697 5 5 0,000 0,03370314 0,09134542 ! hair follicle maturation GO:0048820 5 5 0,000 0,03370314 0,09121129 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03370314 0,09107755 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03370314 0,0909442 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03370314 0,09081124 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03370314 0,09067867 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03370314 0,09054648 ! postreplication repair GO:0006301 5 5 0,000 0,03370314 0,09041468 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03370314 0,09028326 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,03370314 0,09015223 ! DNA methylation GO:0006306 5 5 0,000 0,03370314 0,09002157 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03370314 0,0898913 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03370314 0,0897614 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03370314 0,08963187 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03370314 0,08950272 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03370314 0,08937394 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03370314 0,08924553 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03370314 0,08911748 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03370314 0,08898981 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03370314 0,0888625 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03370314 0,08873555 ! sterol catabolic process GO:0016127 5 5 0,000 0,03370314 0,08860897 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03370314 0,08848274 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03370314 0,08835688 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03370314 0,08823137 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03370314 0,08810622 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! zymogen activation GO:0031638 5 5 0,000 0,03370314 0,08798142 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03370314 0,08785698 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03370314 0,08773289 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03370314 0,08760915 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03370314 0,08748575 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03370314 0,08736271 ! nucleosome positioning GO:0016584 5 5 0,000 0,03370314 0,08724001 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03370314 0,08711765 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03370314 0,08699564 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03370314 0,08687397 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03370314 0,08675263 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03370314 0,08663164 ! NADPH regeneration GO:0006740 5 5 0,000 0,03370314 0,08651098 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03370314 0,08639066 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03370314 0,08627067 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03370314 0,08615102 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03370314 0,0860317 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03370314 0,08591271 ! sarcomere organization GO:0045214 5 5 0,000 0,03370314 0,08579404 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03370314 0,0856757 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03370314 0,08555769 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03370314 0,08544001 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03370314 0,08532265 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03370314 0,0852056 ! male genitalia development GO:0030539 5 5 0,000 0,03370314 0,08508888 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03370314 0,08497248 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03370314 0,0848564 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03370314 0,08474064 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03370314 0,08462518 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03370314 0,08451005 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03370314 0,08439523 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03370314 0,08428071 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03370314 0,08416651 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03370314 0,08405262 ! ATP catabolic process GO:0006200 5 5 0,000 0,03370314 0,08393903 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03370314 0,08382576 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03370314 0,08371278 ! blastocyst formation GO:0001825 5 5 0,000 0,03370314 0,08360012 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03370314 0,08348775 ! embryonic gut development GO:0048566 5 5 0,000 0,03370314 0,08337569 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03370314 0,08326392 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03370314 0,08315246 ! activation of innate immune response GO:0002218 5 5 0,000 0,03370314 0,08304129 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03370314 0,08293042 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03370314 0,08281985 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03370314 0,08270957 ! muscle adaptation GO:0043500 5 5 0,000 0,03370314 0,08259958 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03370314 0,08248989 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03370314 0,08238049 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03370314 0,08227137 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03370314 0,08216255 ! defense response to fungus GO:0050832 5 5 0,000 0,03370314 0,08205401 ! lysogeny GO:0030069 5 5 0,000 0,03370314 0,08194576 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03370314 0,08183779 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03370314 0,08173011 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03370314 0,08162271 ! mitochondrion localization GO:0051646 5 5 0,000 0,03370314 0,0815156 ! nucleus localization GO:0051647 5 5 0,000 0,03370314 0,08140876 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03370314 0,08130221 ! reproductive structure development GO:0048608 43 43 1,000 0,03453774 0,08320661 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,03453774 0,08309799 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03453774 0,08298964 ! humoral immune response GO:0006959 44 44 1,000 0,03602751 0,08645665 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,03602751 0,08634422 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03602751 0,08623208 ! vitamin metabolic process GO:0006766 44 44 1,000 0,03602751 0,08612024 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,03754189 0,08962398 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,03754189 0,08950803 ! regulation of DNA binding GO:0051101 47 45 1,000 0,03754189 0,08939239 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,03754189 0,08927704 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,03754189 0,089162 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,0390805 0,09269672 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,0390805 0,09257757 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,0390805 0,09245873 ! axon extension GO:0048675 7 6 0,000 0,0403091 0,09524316 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,0403091 0,09512121 ! tRNA modification GO:0006400 6 6 0,000 0,0403091 0,09499957 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,0403091 0,09487824 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,0403091 0,09475722 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,0403091 0,09463651 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,0403091 0,09451611 ! regulation of S phase GO:0033261 6 6 0,000 0,0403091 0,09439602 ! myotube differentiation GO:0014902 6 6 0,000 0,0403091 0,09427622 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,0403091 0,09415674 ! bone remodeling GO:0046849 6 6 0,000 0,0403091 0,09403755 ! N-glycan processing GO:0006491 6 6 0,000 0,0403091 0,09391866 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,0403091 0,09380008 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,0403091 0,0936818 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,0403091 0,09356381 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,0403091 0,09344612 ! RNA methylation GO:0001510 6 6 0,000 0,0403091 0,09332872 ! cartilage condensation GO:0001502 7 6 0,000 0,0403091 0,09321162 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,0403091 0,09309482 ! artery development GO:0060840 6 6 0,000 0,0403091 0,0929783 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,0403091 0,09286208 ! bile acid metabolic process GO:0008206 6 6 0,000 0,0403091 0,09274615 ! androgen metabolic process GO:0008209 6 6 0,000 0,0403091 0,0926305 ! estrogen metabolic process GO:0008210 6 6 0,000 0,0403091 0,09251515 ! limbic system development GO:0021761 7 6 0,000 0,0403091 0,09240008 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,0403091 0,0922853 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,0403091 0,0921708 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,0403091 0,09205658 ! pathogenesis GO:0009405 6 6 0,000 0,0403091 0,09194265 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,0403091 0,091829 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,0403091 0,09171563 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,0403091 0,09160254 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,0403091 0,09148973 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,0403091 0,0913772 ! arginine metabolic process GO:0006525 6 6 0,000 0,0403091 0,09126494 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,0403091 0,09115296 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,0403091 0,09104125 ! glutamate catabolic process GO:0006538 7 6 0,000 0,0403091 0,09092982 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,0403091 0,09081866 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,0403091 0,09070777 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,0403091 0,09059715 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,0403091 0,0904868 ! ER overload response GO:0006983 6 6 0,000 0,0403091 0,09037672 ! V(D)J recombination GO:0033151 6 6 0,000 0,0403091 0,09026691 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,0403091 0,09015736 ! lipid digestion GO:0044241 6 6 0,000 0,0403091 0,09004808 ! asymmetric protein localization GO:0008105 6 6 0,000 0,0403091 0,08993906 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,0403091 0,08983031 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,0403091 0,08972182 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,0403091 0,08961359 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,0403091 0,08950562 ! ruffle organization GO:0031529 6 6 0,000 0,0403091 0,08939791 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,0403091 0,08929046 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,0403091 0,08918327 ! neutral amino acid transport GO:0015804 6 6 0,000 0,0403091 0,08907634 ! L-amino acid transport GO:0015807 6 6 0,000 0,0403091 0,08896966 ! bone mineralization GO:0030282 6 6 0,000 0,0403091 0,08886323 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,0403091 0,08875707 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,0403091 0,08865115 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,0403091 0,08854549 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,0403091 0,08844008 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,0403091 0,08833492 ! regulation of organ growth GO:0046620 6 6 0,000 0,0403091 0,08823 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,0403091 0,08812534 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,0403091 0,08802093 ! response to dsRNA GO:0043331 6 6 0,000 0,0403091 0,08791676 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,0403091 0,08781284 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,0403091 0,08770917 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,0403091 0,08760574 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,0403091 0,08750255 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,0403091 0,0873996 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,0403091 0,0872969 ! multicellular organismal aging GO:0010259 6 6 0,000 0,0403091 0,08719444 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,0403091 0,08709222 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,0403091 0,08699024 ! erythrocyte development GO:0048821 6 6 0,000 0,0403091 0,0868885 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,0403091 0,08678699 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,0403091 0,08668572 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,0403091 0,08658469 ! ribosome assembly GO:0042255 6 6 0,000 0,0403091 0,08648389 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,0403091 0,08638333 ! diencephalon development GO:0021536 6 6 0,000 0,0403091 0,086283 ! fucose catabolic process GO:0019317 6 6 0,000 0,0403091 0,0861829 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,0403091 0,08608304 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,0403091 0,08598341 ! regulation of lipid transport GO:0032368 6 6 0,000 0,0403091 0,085884 ! regulation of cell division GO:0051302 6 6 0,000 0,0403091 0,08578483 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,0403091 0,08568589 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,0403091 0,08558717 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,0403091 0,08548868 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,0403091 0,08539042 ! neuroblast proliferation GO:0007405 6 6 0,000 0,0403091 0,08529238 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,0403091 0,08519457 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,0403091 0,08509698 ! regulation of glucose transport GO:0010827 6 6 0,000 0,0403091 0,08499962 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,0403091 0,08490247 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,0403091 0,08480555 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,0403091 0,08470885 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,0403091 0,08461237 ! lymph node development GO:0048535 6 6 0,000 0,0403091 0,08451611 ! organic cation transport GO:0015695 6 6 0,000 0,0403091 0,08442007 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,0403091 0,08432425 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,0403091 0,08422864 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,0403091 0,08413325 ! sperm-egg recognition GO:0035036 7 6 0,000 0,0403091 0,08403808 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,0403091 0,08394312 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,0403091 0,08384838 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,0403091 0,08375385 ! alditol metabolic process GO:0019400 6 6 0,000 0,0403091 0,08365953 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,0403091 0,08356543 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,0403091 0,08347153 ! maternal placenta development GO:0001893 6 6 0,000 0,0403091 0,08337785 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,0403091 0,08328438 ! regulation of blood pressure GO:0008217 48 47 1,000 0,04064293 0,08388009 ! sex differentiation GO:0007548 47 47 1,000 0,04064293 0,08378627 ! amine transport GO:0015837 47 47 1,000 0,04064293 0,08369265 ! rhythmic process GO:0048511 47 47 1,000 0,04064293 0,08359925 ! regulation of catabolic process GO:0009894 48 47 1,000 0,04064293 0,08350605 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,04222882 0,08666784 ! protein localization in nucleus GO:0034504 48 48 1,000 0,04222882 0,08657143 ! leukocyte differentiation GO:0002521 50 49 1,000 0,04383779 0,08977004 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,04383779 0,08967041 ! regulation of ligase activity GO:0051340 50 49 1,000 0,04383779 0,089571 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,04546945 0,09280199 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,04546945 0,09269933 ! respiratory burst GO:0045730 7 7 0,000 0,04687085 0,0954508 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04687085 0,09534544 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04687085 0,09524032 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04687085 0,09513543 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04687085 0,09503077 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04687085 0,09492634 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04687085 0,09482214 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04687085 0,09471817 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04687085 0,09461442 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,04687085 0,09451091 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04687085 0,09440762 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04687085 0,09430455 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04687085 0,09420171 ! axis specification GO:0009798 7 7 0,000 0,04687085 0,0940991 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04687085 0,0939967 ! visual behavior GO:0007632 7 7 0,000 0,04687085 0,09389453 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04687085 0,09379258 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04687085 0,09369086 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04687085 0,09358935 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04687085 0,09348806 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04687085 0,09338699 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04687085 0,09328614 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04687085 0,09318551 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04687085 0,0930851 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04687085 0,0929849 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04687085 0,09288491 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04687085 0,09278515 ! protein targeting to ER GO:0045047 8 7 0,000 0,04687085 0,09268559 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04687085 0,09258625 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04687085 0,09248712 ! endoderm development GO:0007492 7 7 0,000 0,04687085 0,0923882 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04687085 0,0922895 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04687085 0,092191 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04687085 0,09209272 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04687085 0,09199464 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04687085 0,09189678 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04687085 0,09179912 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04687085 0,09170167 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04687085 0,09160442 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04687085 0,09150738 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04687085 0,09141055 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04687085 0,09131392 ! response to X-ray GO:0010165 7 7 0,000 0,04687085 0,0912175 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04687085 0,09112128 ! UV protection GO:0009650 7 7 0,000 0,04687085 0,09102526 ! DNA integration GO:0015074 7 7 0,000 0,04687085 0,09092944 ! myofibril assembly GO:0030239 7 7 0,000 0,04687085 0,09083383 GO:0055002|striated muscle cell development, ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04687085 0,09073841 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04687085 0,0906432 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04687085 0,09054819 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04687085 0,09045337 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04687085 0,09035876 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04687085 0,09026434 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04687085 0,09017011 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04687085 0,09007609 ! axon cargo transport GO:0008088 7 7 0,000 0,04687085 0,08998226 ! eating behavior GO:0042755 7 7 0,000 0,04687085 0,08988863 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04687085 0,08979519 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04687085 0,08970194 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04687085 0,08960889 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04687085 0,08951603 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04687085 0,08942336 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04687085 0,08933089 ! induction of an organ GO:0001759 7 7 0,000 0,04687085 0,08923861 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04687085 0,08914651 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04687085 0,08905461 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04687085 0,08896289 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04687085 0,08887137 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04687085 0,08878003 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04687085 0,08868888 ! natural killer cell activation GO:0030101 7 7 0,000 0,04687085 0,08859792 ! NADP metabolic process GO:0006739 7 7 0,000 0,04687085 0,08850714 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04687085 0,08841655 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04687085 0,08832615 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04687085 0,08823592 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04687085 0,08814589 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04687085 0,08805603 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04687085 0,08796636 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04687085 0,08787688 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04687085 0,08778757 ! cell-cell recognition GO:0009988 8 7 0,000 0,04687085 0,08769845 ! hormone catabolic process GO:0042447 7 7 0,000 0,04687085 0,0876095 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04687085 0,08752074 ! oxygen transport GO:0015671 7 7 0,000 0,04687085 0,08743216 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04687085 0,08734375 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04687085 0,08725553 ! regulation of axon extension GO:0030516 7 7 0,000 0,04687085 0,08716748 ! cell killing GO:0001906 7 7 0,000 0,04687085 0,08707961 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04687085 0,08699191 ! adult feeding behavior GO:0008343 7 7 0,000 0,04687085 0,0869044 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04687085 0,08681706 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04687085 0,08672989 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04687085 0,0866429 ! response to cold GO:0009409 7 7 0,000 0,04687085 0,08655608 ! cell fate commitment GO:0045165 52 52 1,000 0,0487994 0,09002732 ! regulation of T cell activation GO:0050863 53 53 1,000 0,05049696 0,09306589 ! regulation of protein transport GO:0051223 53 53 1,000 0,05049696 0,09297292 GO:0070201|regulation of establishment of protein localization, ! sulfur metabolic process GO:0006790 55 54 1,000 0,05221575 0,09604155 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05338868 0,09810103 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05338868 0,09800332 ! positive regulation of translation GO:0045727 8 8 0,000 0,05338868 0,09790581 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05338868 0,09780849 ! superoxide anion generation GO:0042554 8 8 0,000 0,05338868 0,09771136 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05338868 0,09761442 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05338868 0,09751768 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05338868 0,09742113 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05338868 0,09732476 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05338868 0,09722859 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05338868 0,09713261 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05338868 0,09703682 ! zinc ion transport GO:0006829 8 8 0,000 0,05338868 0,09694122 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05338868 0,0968458 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05338868 0,09675058 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05338868 0,09665554 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05338868 0,09656068 ! lipid localization GO:0010876 8 8 0,000 0,05338868 0,09646602 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05338868 0,09637154 ! response to cAMP GO:0051591 8 8 0,000 0,05338868 0,09627724 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05338868 0,09618313 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05338868 0,0960892 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05338868 0,09599545 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05338868 0,09590189 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05338868 0,09580851 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05338868 0,09571531 ! sensory perception of taste GO:0050909 8 8 0,000 0,05338868 0,09562229 ! organelle fusion GO:0048284 8 8 0,000 0,05338868 0,09552945 ! pancreas development GO:0031016 8 8 0,000 0,05338868 0,0954368 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05338868 0,09534432 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05338868 0,09525202 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05338868 0,0951599 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05338868 0,09506796 ! sperm motility GO:0030317 8 8 0,000 0,05338868 0,09497619 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05338868 0,09488461 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05338868 0,0947932 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05338868 0,09470196 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05338868 0,0946109 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05338868 0,09452002 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05338868 0,09442931 ! Golgi organization GO:0007030 8 8 0,000 0,05338868 0,09433877 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05338868 0,09424841 ! fructose metabolic process GO:0006000 8 8 0,000 0,05338868 0,09415822 ! mannose metabolic process GO:0006013 9 8 0,000 0,05338868 0,0940682 ! NAD metabolic process GO:0019674 8 8 0,000 0,05338868 0,09397835 ! response to fungus GO:0009620 8 8 0,000 0,05338868 0,09388868 ! stem cell differentiation GO:0048863 8 8 0,000 0,05338868 0,09379918 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05338868 0,09370985 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05338868 0,09362068 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05338868 0,09353169 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05338868 0,09344287 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05338868 0,09335421 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05338868 0,09326572 ! muscle cell development GO:0055001 8 8 0,000 0,05338868 0,0931774 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05338868 0,09308925 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05338868 0,09300126 ! sensory perception of pain GO:0019233 8 8 0,000 0,05338868 0,09291344 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05338868 0,09282579 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05338868 0,0927383 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05338868 0,09265098 ! chromatin silencing GO:0006342 8 8 0,000 0,05338868 0,09256382 ! tissue regeneration GO:0042246 8 8 0,000 0,05338868 0,09247682 ! salivary gland development GO:0007431 8 8 0,000 0,05338868 0,09238999 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05338868 0,09230332 ! cofactor transport GO:0051181 8 8 0,000 0,05338868 0,09221681 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05338868 0,09213047 ! acid secretion GO:0046717 8 8 0,000 0,05338868 0,09204428 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05338868 0,09195826 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05338868 0,0918724 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05338868 0,0917867 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05338868 0,09170115 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05338868 0,09161577 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05338868 0,09153055 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05338868 0,09144548 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05338868 0,09136057 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05338868 0,09127582 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05338868 0,09119123 ! developmental induction GO:0031128 8 8 0,000 0,05338868 0,09110679 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05338868 0,09102251 ! actin filament polymerization GO:0030041 9 8 0,000 0,05338868 0,09093839 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05338868 0,09085442 ! peptide hormone processing GO:0016486 8 8 0,000 0,05338868 0,09077061 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05338868 0,09068695 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05338868 0,09060344 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05395544 0,09148102 ! in utero embryonic development GO:0001701 55 55 1,000 0,05395544 0,09139694 ! extracellular structure organization GO:0043062 56 56 1,000 0,05571565 0,09429196 ! regulation of nervous system development GO:0051960 57 56 1,000 0,05571565 0,09420545 ! lactation GO:0007595 10 9 0,000 0,05986288 0,10112493 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05986288 0,10103232 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,05986288 0,10093989 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05986288 0,10084762 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05986288 0,10075552 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05986288 0,10066359 ! viral genome replication GO:0019079 9 9 0,000 0,05986288 0,10057183 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05986288 0,10048023 ! copper ion transport GO:0006825 9 9 0,000 0,05986288 0,1003888 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05986288 0,10029754 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05986288 0,10020644 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05986288 0,10011551 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05986288 0,10002475 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05986288 0,09993414 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05986288 0,09984371 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05986288 0,09975343 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05986288 0,09966332 ! phospholipid efflux GO:0033700 9 9 0,000 0,05986288 0,09957337 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05986288 0,09948359 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05986288 0,09939396 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05986288 0,0993045 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05986288 0,09921519 ! methionine metabolic process GO:0006555 9 9 0,000 0,05986288 0,09912605 ! cerebral cortex development GO:0021987 9 9 0,000 0,05986288 0,09903707 ! response to osmotic stress GO:0006970 9 9 0,000 0,05986288 0,09894825 ! pigmentation during development GO:0048066 9 9 0,000 0,05986288 0,09885958 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05986288 0,09877108 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05986288 0,09868273 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05986288 0,09859454 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05986288 0,09850651 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05986288 0,09841864 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05986288 0,09833092 ! L-glutamate transport GO:0015813 9 9 0,000 0,05986288 0,09824336 GO:0015800|acidic amino acid transport, ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05986288 0,09815596 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05986288 0,09806871 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05986288 0,09798161 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05986288 0,09789467 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05986288 0,09780789 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05986288 0,09772125 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,05986288 0,09763478 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05986288 0,09754845 GO:0006692|prostanoid metabolic process, ! regulation of cellular pH GO:0030641 9 9 0,000 0,05986288 0,09746228 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05986288 0,09737625 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05986288 0,09729038 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05986288 0,09720467 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05986288 0,0971191 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05986288 0,09703368 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05986288 0,09694841 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05986288 0,0968633 ! collagen catabolic process GO:0030574 9 9 0,000 0,05986288 0,09677833 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05986288 0,09669351 ! gas transport GO:0015669 9 9 0,000 0,05986288 0,09660884 ! cholesterol efflux GO:0033344 9 9 0,000 0,05986288 0,09652432 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05986288 0,09643994 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05986288 0,09635572 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05986288 0,09627164 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05986288 0,0961877 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05986288 0,09610392 ! actin filament-based movement GO:0030048 9 9 0,000 0,05986288 0,09602027 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05986288 0,09593678 ! carboxylic acid transport GO:0046942 59 59 1,000 0,06111604 0,09786 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,06111604 0,09777505 ! protein localization in organelle GO:0033365 59 59 1,000 0,06111604 0,09769025 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,06295494 0,10054242 ! protein polymerization GO:0051258 65 60 1,000 0,06295494 0,10045537 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,06481267 0,10333024 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06629375 0,10560015 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06629375 0,10550896 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06629375 0,10541792 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06629375 0,10532705 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06629375 0,10523632 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06629375 0,10514576 ! neuron maturation GO:0042551 10 10 0,000 0,06629375 0,10505535 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06629375 0,1049651 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06629375 0,104875 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06629375 0,10478505 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06629375 0,10469526 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06629375 0,10460563 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06629375 0,10451614 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06629375 0,10442681 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,06629375 0,10433764 ! inositol metabolic process GO:0006020 10 10 0,000 0,06629375 0,10424861 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06629375 0,10415974 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06629375 0,10407102 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06629375 0,10398244 ! glial cell development GO:0021782 10 10 0,000 0,06629375 0,10389402 ! phototransduction GO:0007602 11 10 0,000 0,06629375 0,10380575 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,06629375 0,10371763 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06629375 0,10362966 ! fat cell differentiation GO:0045444 10 10 0,000 0,06629375 0,10354184 ! myoblast differentiation GO:0045445 10 10 0,000 0,06629375 0,10345417 ! centrosome cycle GO:0007098 10 10 0,000 0,06629375 0,10336664 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06629375 0,10327927 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06629375 0,10319204 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06629375 0,10310496 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06629375 0,10301802 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06629375 0,10293123 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06629375 0,10284459 ! plasma membrane organization GO:0007009 10 10 0,000 0,06629375 0,10275809 ! lysosomal transport GO:0007041 10 10 0,000 0,06629375 0,10267174 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06629375 0,10258554 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06629375 0,10249947 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06629375 0,10241356 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06629375 0,10232778 ! exocrine system development GO:0035272 10 10 0,000 0,06629375 0,10224215 ! embryo implantation GO:0007566 11 10 0,000 0,06629375 0,10215667 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06629375 0,10207132 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06629375 0,10198612 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06629375 0,10190106 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,06629375 0,10181614 ! protein export from nucleus GO:0006611 10 10 0,000 0,06629375 0,10173137 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06629375 0,10164673 ! cytolysis GO:0019835 10 10 0,000 0,06629375 0,10156224 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06629375 0,10147788 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06629375 0,10139367 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06629375 0,1013096 ! histone deacetylation GO:0016575 10 10 0,000 0,06629375 0,10122566 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06629375 0,10114186 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06629375 0,10105821 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06629375 0,10097469 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06629375 0,10089131 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06629375 0,10080806 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06629375 0,10072496 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06629375 0,10064199 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06629375 0,10055915 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06629375 0,10047646 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06629375 0,1003939 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06629375 0,10031147 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06629375 0,10022918 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06629375 0,10014703 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06629375 0,10006501 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06629375 0,09998312 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,06629375 0,09990137 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06629375 0,09981975 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06629375 0,09973826 ! protein stabilization GO:0050821 10 10 0,000 0,06629375 0,09965691 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,06668891 0,10016924 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,06668891 0,10008767 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,06858331 0,10284706 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,07049556 0,10562871 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,07049556 0,1055429 ! protein secretion GO:0009306 11 11 0,000 0,07268155 0,10872735 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07268155 0,10863916 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07268155 0,10855113 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07268155 0,10846323 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07268155 0,10837548 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07268155 0,10828787 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07268155 0,1082004 ! skin development GO:0043588 11 11 0,000 0,07268155 0,10811307 ! microtubule-based transport GO:0010970 11 11 0,000 0,07268155 0,10802588 ! endothelial cell migration GO:0043542 11 11 0,000 0,07268155 0,10793883 ! peroxisomal transport GO:0043574 11 11 0,000 0,07268155 0,10785192 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07268155 0,10776516 GO:0008213|protein amino acid alkylation, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,07268155 0,10767853 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,07268155 0,10759204 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07268155 0,10750569 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07268155 0,10741948 ! T cell proliferation GO:0042098 11 11 0,000 0,07268155 0,10733341 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07268155 0,10724747 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07268155 0,10716167 ! spinal cord development GO:0021510 11 11 0,000 0,07268155 0,10707601 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07268155 0,10699049 ! cellular response to starvation GO:0009267 11 11 0,000 0,07268155 0,1069051 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07268155 0,10681985 ! digestive system process GO:0022600 11 11 0,000 0,07268155 0,10673473 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07268155 0,10664975 ! fucose metabolic process GO:0006004 11 11 0,000 0,07268155 0,10656491 ! membrane budding GO:0006900 11 11 0,000 0,07268155 0,1064802 ! monoamine transport GO:0015844 11 11 0,000 0,07268155 0,10639562 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07268155 0,10631118 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07268155 0,10622688 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07268155 0,1061427 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07268155 0,10605866 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07268155 0,10597475 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07268155 0,10589098 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07268155 0,10580734 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07268155 0,10572383 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07268155 0,10564045 ! vitamin transport GO:0051180 11 11 0,000 0,07268155 0,1055572 ! muscle maintenance GO:0046716 12 11 0,000 0,07268155 0,10547409 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07268155 0,1053911 ! steroid catabolic process GO:0006706 11 11 0,000 0,07268155 0,10530825 ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07268155 0,10522552 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07268155 0,10514293 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07268155 0,10506046 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07268155 0,10497813 ! protein amino acid glycosylation GO:0006486 66 66 1,000 0,07437233 0,1073361 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 1,000 0,07437233 0,10725211 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,07437233 0,10716826 ! muscle contraction GO:0006936 67 67 1,000 0,07633622 0,10991222 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,07633622 0,10982642 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,07831669 0,11258788 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,07902657 0,11351985 ! translational initiation GO:0006413 12 12 0,000 0,07902657 0,11343144 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07902657 0,11334317 ! initiation of viral infection GO:0019059 12 12 0,000 0,07902657 0,11325503 ! iron ion transport GO:0006826 13 12 0,000 0,07902657 0,11316703 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07902657 0,11307917 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07902657 0,11299144 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07902657 0,11290385 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07902657 0,1128164 ! collagen metabolic process GO:0032963 12 12 0,000 0,07902657 0,11272908 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07902657 0,11264189 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,07902657 0,11255484 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,07902657 0,11246793 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07902657 0,11238115 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07902657 0,1122945 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07902657 0,11220799 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,07902657 0,11212161 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07902657 0,11203536 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07902657 0,11194925 GO:0016101|diterpenoid metabolic process, ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07902657 0,11186326 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07902657 0,11177741 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,07902657 0,11169169 ! acute-phase response GO:0006953 12 12 0,000 0,07902657 0,11160611 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07902657 0,11152065 ! vacuolar transport GO:0007034 12 12 0,000 0,07902657 0,11143532 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07902657 0,11135013 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07902657 0,11126506 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07902657 0,11118013 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07902657 0,11109532 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,07902657 0,11101065 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,07902657 0,1109261 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07902657 0,11084168 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07902657 0,11075739 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,07902657 0,11067323 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07902657 0,11058919 ! pallium development GO:0021543 13 12 0,000 0,07902657 0,11050529 ! cell fate determination GO:0001709 12 12 0,000 0,07902657 0,11042151 ! G1 phase GO:0051318 13 12 0,000 0,07902657 0,11033785 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07902657 0,11025433 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07902657 0,11017093 ! detection of light stimulus GO:0009583 13 12 0,000 0,07902657 0,11008766 ! synaptogenesis GO:0007416 12 12 0,000 0,07902657 0,11000451 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07902657 0,10992149 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07902657 0,10983859 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07902657 0,10975582 ! spermatid differentiation GO:0048515 13 12 0,000 0,07902657 0,10967317 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,07902657 0,10959065 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07902657 0,10950825 ! neural tube closure GO:0001843 13 12 0,000 0,07902657 0,10942597 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,07902657 0,10934382 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,07902657 0,10926179 ! regulation of translation GO:0006417 69 69 1,000 0,08031345 0,11095778 ! sensory perception of sound GO:0007605 71 69 1,000 0,08031345 0,11087467 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,08031345 0,11079168 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,08435459 0,11627937 ! regulation of cell activation GO:0050865 71 71 1,000 0,08435459 0,11619246 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,0853291 0,11744699 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,0853291 0,11735935 ! phenol metabolic process GO:0018958 13 13 0,000 0,0853291 0,11727183 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,0853291 0,11718444 ! gluconeogenesis GO:0006094 13 13 0,000 0,0853291 0,11709719 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,0853291 0,11701006 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,0853291 0,11692307 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,0853291 0,1168362 ! keratinization GO:0031424 13 13 0,000 0,0853291 0,11674946 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,0853291 0,11666285 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,0853291 0,11657637 ! regulation of innate immune response GO:0045088 13 13 0,000 0,0853291 0,11649002 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,0853291 0,11640379 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,0853291 0,1163177 ! autophagy GO:0006914 13 13 0,000 0,0853291 0,11623173 ! receptor metabolic process GO:0043112 14 13 0,000 0,0853291 0,11614588 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,0853291 0,11606017 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,0853291 0,11597458 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,0853291 0,11588911 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,0853291 0,11580377 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,0853291 0,11571856 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,0853291 0,11563347 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,0853291 0,11554851 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,0853291 0,11546367 ! vasodilation GO:0042311 14 13 0,000 0,0853291 0,11537896 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,0853291 0,11529437 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,0853291 0,11520991 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,0853291 0,11512557 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,0853291 0,11504135 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,0853291 0,11495725 ! immunoglobulin production GO:0002377 13 13 0,000 0,0853291 0,11487328 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,0853291 0,11478943 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,0853291 0,11470571 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,0853291 0,1146221 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,0853291 0,11453862 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,0853291 0,11445526 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,0853291 0,11437202 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,0853291 0,1142889 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,0853291 0,1142059 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,0853291 0,11412302 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,0853291 0,11404026 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,0853291 0,11395763 ! blastocyst development GO:0001824 13 13 0,000 0,0853291 0,11387511 ! telomere organization GO:0032200 13 13 0,000 0,0853291 0,11379271 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,0853291 0,11371043 ! regulation of amine transport GO:0051952 13 13 0,000 0,0853291 0,11362827 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,0853291 0,11354623 ! secretion by cell GO:0032940 75 72 1,000 0,08639839 0,11488616 ! muscle system process GO:0003012 72 72 1,000 0,08639839 0,11480333 ! neuron fate commitment GO:0048663 14 14 0,000 0,0915894 0,12161331 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,0915894 0,12152575 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,0915894 0,12143832 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,0915894 0,12135102 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,0915894 0,12126384 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,0915894 0,12117679 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,0915894 0,12108986 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,0915894 0,12100306 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,0915894 0,12091638 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,0915894 0,12082983 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,0915894 0,1207434 ! vesicle docking GO:0048278 14 14 0,000 0,0915894 0,12065709 ! superoxide metabolic process GO:0006801 15 14 0,000 0,0915894 0,12057091 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,0915894 0,12048485 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,0915894 0,12039891 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,0915894 0,12031309 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,0915894 0,1202274 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,0915894 0,12014183 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,0915894 0,12005638 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 14 14 0,000 0,0915894 0,11997105 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,0915894 0,11988585 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,0915894 0,11980076 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,0915894 0,1197158 GO:0045936|negative regulation of phosphate metabolic process, ! primary neural tube formation GO:0014020 15 14 0,000 0,0915894 0,11963095 ! peptide cross-linking GO:0018149 14 14 0,000 0,0915894 0,11954623 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,0915894 0,11946162 ! base-excision repair GO:0006284 14 14 0,000 0,0915894 0,11937714 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,0915894 0,11929277 ! formation of primary germ layer GO:0001704 14 14 0,000 0,0915894 0,11920853 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,0915894 0,1191244 ! collagen fibril organization GO:0030199 14 14 0,000 0,0915894 0,11904039 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,0915894 0,1189565 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,0915894 0,11887273 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,0915894 0,11878907 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,0915894 0,11870554 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,0915894 0,11862212 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,0915894 0,11853881 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,0915894 0,11845563 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,0915894 0,11837256 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,09261912 0,11961951 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,09261912 0,11953574 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,09472152 0,12216359 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,09780777 0,12605575 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,09780777 0,12596766 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09780777 0,12587969 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09780777 0,12579185 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,09780777 0,12570413 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09780777 0,12561653 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09780777 0,12552905 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09780777 0,1254417 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,09780777 0,12535446 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,09780777 0,12526735 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,09780777 0,12518036 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09780777 0,12509349 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09780777 0,12500674 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09780777 0,12492011 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09780777 0,1248336 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,09780777 0,12474721 ! heme metabolic process GO:0042168 15 15 0,000 0,09780777 0,12466094 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09780777 0,12457479 ! response to starvation GO:0042594 15 15 0,000 0,09780777 0,12448876 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09780777 0,12440284 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09780777 0,12431705 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09780777 0,12423137 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09780777 0,12414581 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09780777 0,12406037 ! phospholipid transport GO:0015914 15 15 0,000 0,09780777 0,12397505 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09780777 0,12388984 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09780777 0,12380475 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09780777 0,12371978 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,09780777 0,12363492 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,09780777 0,12355018 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09780777 0,12346556 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,09780777 0,12338105 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09780777 0,12329666 ! protein homooligomerization GO:0051260 15 15 0,000 0,09780777 0,12321238 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09780777 0,12312822 ! microtubule-based movement GO:0007018 82 78 1,000 0,09896788 0,12450362 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,09896788 0,12441869 ! glycoprotein biosynthetic process GO:0009101 80 80 1,000 0,10326779 0,12973588 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,10398447 0,13054726 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10398447 0,13045839 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,10398447 0,13036964 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10398447 0,13028102 ! learning GO:0007612 16 16 0,000 0,10398447 0,13019251 ! circadian rhythm GO:0007623 16 16 0,000 0,10398447 0,13010412 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10398447 0,13001586 ! vacuole organization GO:0007033 16 16 0,000 0,10398447 0,12992771 ! vesicle targeting GO:0006903 17 16 0,000 0,10398447 0,12983968 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10398447 0,12975178 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10398447 0,12966399 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,10398447 0,12957632 ! cell fate specification GO:0001708 16 16 0,000 0,10398447 0,12948877 ! pentose metabolic process GO:0019321 16 16 0,000 0,10398447 0,12940133 ! fatty acid transport GO:0015908 16 16 0,000 0,10398447 0,12931402 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10398447 0,12922682 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,10398447 0,12913974 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,10398447 0,12905278 ! cofactor catabolic process GO:0051187 16 16 0,000 0,10398447 0,12896593 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10398447 0,1288792 ! polyol metabolic process GO:0019751 16 16 0,000 0,10398447 0,12879259 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10398447 0,12870609 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10398447 0,12861971 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10398447 0,12853345 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10398447 0,1284473 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,10398447 0,12836127 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,10398447 0,12827535 ! lipid catabolic process GO:0016042 82 81 1,000 0,10543715 0,12998038 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,10981335 0,13528476 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,11011977 0,13557164 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,11011977 0,13548114 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,11011977 0,13539075 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,11011977 0,13530049 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,11011977 0,13521035 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,11011977 0,13512033 ! sensory perception of smell GO:0007608 17 17 0,000 0,11011977 0,13503043 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,11011977 0,13494065 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,11011977 0,13485099 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,11011977 0,13476145 ! negative regulation of cell development GO:0010721 18 17 0,000 0,11011977 0,13467202 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,11011977 0,13458272 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,11011977 0,13449353 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,11011977 0,13440446 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,11011977 0,13431551 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,11011977 0,13422668 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,11011977 0,13413796 ! adult locomotory behavior GO:0008344 17 17 0,000 0,11011977 0,13404937 ! embryonic organ development GO:0048568 17 17 0,000 0,11011977 0,13396088 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,11011977 0,13387252 ! liver development GO:0001889 17 17 0,000 0,11011977 0,13378427 ! gene silencing GO:0016458 17 17 0,000 0,11011977 0,13369614 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,11201966 0,13591325 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,11423776 0,13851329 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,11423776 0,13842222 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,11423776 0,13833127 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11621395 0,14063186 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,11621395 0,14053958 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11621395 0,14044742 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11621395 0,14035539 ! membrane docking GO:0022406 18 18 0,000 0,11621395 0,14026347 ! response to calcium ion GO:0051592 18 18 0,000 0,11621395 0,14017167 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11621395 0,14008 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,11621395 0,13998844 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,11621395 0,13989701 ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,11621395 0,13980569 ! ceramide metabolic process GO:0006672 18 18 0,000 0,11621395 0,13971449 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,11621395 0,13962341 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11621395 0,13953245 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,11621395 0,13944161 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,11621395 0,13935089 ! BMP signaling pathway GO:0030509 18 18 0,000 0,11621395 0,13926028 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,11621395 0,1391698 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,11621395 0,13907943 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,11621395 0,13898917 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,11646741 0,13920197 GO:0006644|phospholipid metabolic process, ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,12226728 0,14603928 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,12226728 0,14594469 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,12226728 0,14585023 ! feeding behavior GO:0007631 19 19 0,000 0,12226728 0,14575589 ! peroxisome organization GO:0007031 19 19 0,000 0,12226728 0,14566167 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,12226728 0,14556757 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,12226728 0,1454736 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,12226728 0,14537974 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,12226728 0,14528601 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,12226728 0,1451924 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,12226728 0,14509891 ! eye morphogenesis GO:0048592 19 19 0,000 0,12226728 0,14500554 ! placenta development GO:0001890 19 19 0,000 0,12226728 0,14491229 ! vesicle localization GO:0051648 20 19 0,000 0,12226728 0,14481915 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,12549641 0,14854842 ! DNA replication GO:0006260 91 91 1,000 0,12778004 0,15115444 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,12828003 0,15164855 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,12828003 0,15155134 ! negative regulation of binding GO:0051100 21 20 0,000 0,12828003 0,15145425 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,12828003 0,15135729 ! neural tube development GO:0021915 21 20 0,000 0,12828003 0,15126045 ! phagocytosis GO:0006909 21 20 0,000 0,12828003 0,15116374 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,12828003 0,15106715 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,12828003 0,15097068 ! protein targeting to membrane GO:0006612 22 20 0,000 0,12828003 0,15087434 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,12828003 0,15077812 ! lipid oxidation GO:0034440 20 20 0,000 0,12828003 0,15068202 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,12828003 0,15058605 ! RNA modification GO:0009451 20 20 0,000 0,12828003 0,15049019 ! regulation of B cell activation GO:0050864 20 20 0,000 0,12828003 0,15039446 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,13007374 0,15240044 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,13007374 0,15230362 ! mRNA catabolic process GO:0006402 21 21 0,000 0,13425245 0,15709668 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,13425245 0,156997 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,13425245 0,15689745 ! Notch signaling pathway GO:0007219 22 21 0,000 0,13425245 0,15679802 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,13425245 0,15669872 ! organic anion transport GO:0015711 21 21 0,000 0,13425245 0,15659954 ! cholesterol transport GO:0030301 21 21 0,000 0,13425245 0,15650049 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,13425245 0,15640156 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,13425245 0,15630276 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,13425245 0,15620409 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,13425245 0,15610553 ! regulation of proteolysis GO:0030162 21 21 0,000 0,13425245 0,15600711 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,13425245 0,1559088 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,13425245 0,15581062 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,13425245 0,15571257 ! epidermis development GO:0008544 94 94 1,000 0,13469039 0,15612226 ! RNA export from nucleus GO:0006405 22 22 0,000 0,14018482 0,16238883 ! regulation of ion transport GO:0043269 22 22 0,000 0,14018482 0,16228683 ! odontogenesis GO:0042476 22 22 0,000 0,14018482 0,16218495 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,14018482 0,16208321 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! erythrocyte differentiation GO:0030218 23 22 0,000 0,14018482 0,16198159 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,14018482 0,16188009 ! biopolymer methylation GO:0043414 22 22 0,000 0,14018482 0,16177873 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,14018482 0,16167749 ! detection of external stimulus GO:0009581 23 22 0,000 0,14018482 0,16157638 ! neuron migration GO:0001764 22 22 0,000 0,14018482 0,16147539 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,14018482 0,16137454 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,14018482 0,1612738 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,14018482 0,16117319 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,14018482 0,16107271 ! aerobic respiration GO:0009060 22 22 0,000 0,14018482 0,16097236 ! cytokine production GO:0001816 22 22 0,000 0,14018482 0,16087212 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,14018482 0,16077202 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,14403431 0,1650841 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,1460774 0,16732173 ! viral infectious cycle GO:0019058 23 23 0,000 0,1460774 0,1672178 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,1460774 0,167114 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,1460774 0,16701033 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,1460774 0,16690679 ! endocrine system development GO:0035270 23 23 0,000 0,1460774 0,16680338 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,1460774 0,1667001 ! lipid homeostasis GO:0055088 23 23 0,000 0,1460774 0,16659694 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,1460774 0,16649391 ! ectoderm development GO:0007398 99 99 1,000 0,14639202 0,16674938 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,14875799 0,1693397 ! hemopoiesis GO:0030097 104 100 1,000 0,14875799 0,16923517 ! gliogenesis GO:0042063 24 24 0,000 0,15193045 0,17273771 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,15193045 0,17263121 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,15193045 0,17252485 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,15193045 0,17241861 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,15193045 0,17231251 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,15193045 0,17220654 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,15193045 0,17210069 ! glucan metabolic process GO:0044042 25 24 0,000 0,15193045 0,17199498 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,15774423 0,17846693 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,15774423 0,17835744 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,15774423 0,17824808 ! endosome transport GO:0016197 25 25 0,000 0,15774423 0,17813886 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,15774423 0,17802977 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,15774423 0,17792082 ! gastrulation GO:0007369 25 25 0,000 0,15774423 0,177812 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,15774423 0,17770331 ! regulation of endocytosis GO:0030100 25 25 0,000 0,15774423 0,17759476 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,15774423 0,17748634 ! positive regulation of defense response GO:0031349 26 26 0,000 0,163519 0,18387158 ! glycolysis GO:0006096 26 26 0,000 0,163519 0,18375946 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,163519 0,18364748 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,163519 0,18353564 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,163519 0,18342393 ! cellular defense response GO:0006968 26 26 0,000 0,163519 0,18331236 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,163519 0,18320092 ! double-strand break repair GO:0006302 27 26 0,000 0,163519 0,18308962 ! regulation of protein secretion GO:0050708 26 26 0,000 0,163519 0,18297845 ! chloride transport GO:0006821 27 27 0,000 0,16925501 0,18928215 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,16925501 0,18916736 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,16925501 0,18905272 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,16925501 0,18893821 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,16925501 0,18882384 ! activation of caspase activity GO:0006919 27 27 0,000 0,16925501 0,18870961 ! inner ear development GO:0048839 27 27 0,000 0,16925501 0,18859551 ! defense response to bacterium GO:0042742 27 27 0,000 0,16925501 0,18848156 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,16925501 0,18836774 ! cell growth GO:0016049 27 27 0,000 0,16925501 0,18825406 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,17495252 0,19447375 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,17495252 0,19435653 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,17495252 0,19423945 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,17495252 0,19412251 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,17495252 0,19400571 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,17495252 0,19388905 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,18061177 0,20004056 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,18061177 0,19992042 ! antigen processing and presentation GO:0019882 29 29 0,000 0,18061177 0,19980042 ! tRNA processing GO:0008033 29 29 0,000 0,18061177 0,19968056 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,18061177 0,19956085 ! adult behavior GO:0030534 30 29 0,000 0,18061177 0,19944128 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,18061177 0,19932185 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,18061177 0,19920257 ! transition metal ion transport GO:0000041 31 30 0,000 0,18623303 0,20527959 ! RNA catabolic process GO:0006401 30 30 0,000 0,18623303 0,20515689 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,18623303 0,20503434 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,18623303 0,20491193 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,18623303 0,20478966 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,18623303 0,20466755 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,18623303 0,20454558 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,18623303 0,20442375 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,18623303 0,20430207 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,18623303 0,20418053 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,18623303 0,20405914 ! regulation of translational initiation GO:0006446 31 31 0,000 0,19181654 0,21005222 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,19181654 0,20992749 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,19181654 0,2098029 ! ion transmembrane transport GO:0034220 31 31 0,000 0,19181654 0,20967846 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,19181654 0,20955417 ! digestion GO:0007586 31 31 0,000 0,19181654 0,20943003 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,19181654 0,20930603 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,19181654 0,20918218 ! camera-type eye development GO:0043010 31 31 0,000 0,19181654 0,20905848 ! extracellular matrix organization GO:0030198 31 31 0,000 0,19181654 0,20893492 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,19181654 0,20881151 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,19181654 0,20868825 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,19181654 0,20856513 ! cell redox homeostasis GO:0045454 32 32 0,000 0,19736255 0,21446886 ! glucose catabolic process GO:0006007 32 32 0,000 0,19736255 0,21434248 ! lipid modification GO:0030258 32 32 0,000 0,19736255 0,21421624 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,19736255 0,21409016 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,19736255 0,21396423 ! cell maturation GO:0048469 32 32 0,000 0,19736255 0,21383844 ! nuclear export GO:0051168 32 32 0,000 0,19736255 0,2137128 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,19736255 0,21358731 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,20287131 0,21942008 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,20287131 0,21929139 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,20287131 0,21916285 ! regulation of actin filament length GO:0030832 34 34 0,000 0,20834305 0,22494215 ! muscle cell differentiation GO:0042692 35 34 0,000 0,20834305 0,22481045 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,20834305 0,22467891 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,20834305 0,22454751 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,20834305 0,22441628 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,20834305 0,22428519 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,20834305 0,22415426 ! detection of stimulus GO:0051606 36 34 0,000 0,20834305 0,22402348 ! acute inflammatory response GO:0002526 35 35 0,000 0,21377804 0,22973348 ! regulation of cellular component size GO:0032535 35 35 0,000 0,21377804 0,2295996 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,21377804 0,22946588 ! inorganic anion transport GO:0015698 35 35 0,000 0,21377804 0,22933232 ! regulation of immune effector process GO:0002697 35 35 0,000 0,21377804 0,22919891 ! hydrogen transport GO:0006818 36 36 0,000 0,21917649 0,23485016 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,21917649 0,2347137 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,21917649 0,23457739 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,21917649 0,23444125 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,21917649 0,23430526 ! activation of immune response GO:0002253 36 36 0,000 0,21917649 0,23416943 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,22453866 0,23975942 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,22453866 0,23962059 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,22453866 0,23948192 ! eye development GO:0001654 37 37 0,000 0,22453866 0,23934341 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,22453866 0,23920506 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,22453866 0,23906687 ! neurotransmitter transport GO:0006836 40 38 0,000 0,22986479 0,24459631 ! exocytosis GO:0006887 40 38 0,000 0,22986479 0,24445517 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,22986479 0,24431419 ! hexose catabolic process GO:0019320 38 38 0,000 0,22986479 0,24417338 ! RNA elongation GO:0006354 38 38 0,000 0,22986479 0,24403272 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,22986479 0,24389223 ! response to unfolded protein GO:0006986 39 39 0,000 0,23515511 0,24936183 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,23515511 0,24921844 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,23515511 0,24907521 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,23515511 0,24893214 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,23515511 0,24878924 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,23515511 0,24864651 ! developmental maturation GO:0021700 39 39 0,000 0,23515511 0,24850394 ! limb development GO:0060173 39 39 0,000 0,23515511 0,24836153 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,24040985 0,25376596 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,24040985 0,2536207 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,24040985 0,25347561 ! amine catabolic process GO:0009310 42 41 0,000 0,24562926 0,2588306 ! regulation of caspase activity GO:0043281 41 41 0,000 0,24562926 0,2586827 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,24562926 0,25853496 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,24562926 0,2583874 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,24562926 0,25824 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,24562926 0,25809277 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,25081356 0,26338996 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,25081356 0,26323997 ! protein ubiquitination GO:0016567 43 42 0,000 0,25081356 0,26309015 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,25081356 0,26294049 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! one-carbon metabolic process GO:0006730 42 42 0,000 0,25081356 0,26279101 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,25081356 0,2626417 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,25596298 0,26788176 ! alcohol catabolic process GO:0046164 43 43 0,000 0,25596298 0,26772973 ! mRNA transport GO:0051028 44 44 0,000 0,26107776 0,27292474 ! protein import into nucleus GO:0006606 44 44 0,000 0,26107776 0,27277002 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,26107776 0,27261547 ! amine biosynthetic process GO:0009309 46 45 0,000 0,26615812 0,27776298 ! nuclear import GO:0051170 45 45 0,000 0,26615812 0,27760578 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,26615812 0,27744877 ! protein processing GO:0016485 45 45 0,000 0,26615812 0,27729193 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,27120429 0,28238955 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,27120429 0,2822301 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,27120429 0,28207083 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,27621649 0,28712183 ! calcium ion transport GO:0006816 48 48 0,000 0,28119496 0,29213208 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,28119496 0,29196749 ! DNA recombination GO:0006310 48 48 0,000 0,28119496 0,2918031 ! cell cycle arrest GO:0007050 49 49 0,000 0,2861399 0,29676749 ! divalent metal ion transport GO:0070838 49 49 0,000 0,2861399 0,29660058 ! response to bacterium GO:0009617 50 49 0,000 0,2861399 0,29643386 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,2861399 0,29626732 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,2861399 0,29610097 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,29105154 0,30101458 ! chromatin assembly GO:0031497 50 50 0,000 0,29105154 0,30084576 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,29105154 0,30067712 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,29105154 0,30050867 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,29105154 0,30034042 ! transcription initiation GO:0006352 50 50 0,000 0,29105154 0,30017235 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,2959301 0,3050331 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,2959301 0,30486259 ! positive regulation of immune response GO:0050778 51 51 0,000 0,2959301 0,30469228 ! rRNA metabolic process GO:0016072 51 51 0,000 0,2959301 0,30452215 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,2959301 0,30435222 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,2959301 0,30418247 ! protein maturation GO:0051604 51 51 0,000 0,2959301 0,30401292 ! RNA localization GO:0006403 52 52 0,000 0,3007758 0,30881883 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,3007758 0,30864688 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,3007758 0,30847512 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,3007758 0,30830356 ! sodium ion transport GO:0006814 53 53 0,000 0,30558885 0,31306296 ! tRNA metabolic process GO:0006399 53 53 0,000 0,30558885 0,31288903 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,30558885 0,3127153 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,30558885 0,31254176 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,30558885 0,31236842 ! nucleosome organization GO:0034728 55 55 0,000 0,31511789 0,3219303 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,31511789 0,32175195 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,31511789 0,32157379 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,31983429 0,3262062 ! ATP metabolic process GO:0046034 57 57 0,000 0,3245189 0,33080107 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,3245189 0,33061821 ! innate immune response GO:0045087 58 58 0,000 0,32917193 0,33517341 ! sterol metabolic process GO:0016125 59 59 0,000 0,33379358 0,33969165 ! potassium ion transport GO:0006813 60 60 0,000 0,33838407 0,3441732 ! cellular respiration GO:0045333 62 61 0,000 0,34294359 0,34861834 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,34294359 0,34842615 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,34294359 0,34823418 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,34747236 0,35263852 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,34747236 0,35244445 ! protein import GO:0017038 62 62 0,000 0,34747236 0,35225058 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,34747236 0,35205693 ! glucose metabolic process GO:0006006 63 63 0,000 0,35197057 0,35641855 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,35197057 0,35622282 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,35197057 0,35602731 ! anion transport GO:0006820 65 65 0,000 0,36087613 0,36483528 ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,36528388 0,36908892 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,36528388 0,36888668 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,36966188 0,37310342 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,36966188 0,3728992 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,37401031 0,37707932 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,38261929 0,38554803 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,38688021 0,38962854 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,38688021 0,38941574 ! ribosome biogenesis GO:0042254 71 71 0,000 0,38688021 0,38920318 ! regulation of cytokine production GO:0001817 72 72 0,000 0,39111235 0,39324608 ! electron transport chain GO:0022900 75 74 0,000 0,39949103 0,40145145 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,39949103 0,40123268 ! regulation of immune response GO:0050776 78 78 0,000 0,41591125 0,41749696 ! nuclear transport GO:0051169 79 79 0,000 0,41994714 0,42131877 GO:0006913|nucleocytoplasmic transport, ! ncRNA processing GO:0034470 83 83 0,000 0,43581956 0,43700514 ! hexose metabolic process GO:0019318 87 86 0,000 0,44744412 0,44841736 ! male gamete generation GO:0048232 90 88 0,000 0,45506326 0,45580521 GO:0007283|spermatogenesis, ! visual perception GO:0007601 93 92 0,000 0,46999432 0,4705049 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,46999432 0,47024947 ! cofactor metabolic process GO:0051186 95 94 0,000 0,47730895 0,47730895