pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6902-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of MAP kinase activity GO:0043406 121 85 10,000 1,996E-11 4,59E-08 ! cellular response to hormone stimulus GO:0032870 109 74 9,000 1,093E-10 1,257E-07 ! organ growth GO:0035265 11 7 4,000 3,437E-10 2,635E-07 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 6,000 4,478E-10 2,575E-07 ! positive regulation of cell migration GO:0030335 92 51 7,000 2,516E-09 1,157E-06 ! positive regulation of cell motion GO:0051272 99 56 7,000 5,45E-09 2,089E-06 ! activation of MAPK activity GO:0000187 84 59 7,000 8,358E-09 2,746E-06 ! negative regulation of peptide secretion GO:0002792 6 5 3,000 1,199E-08 3,447E-06 GO:0046676|negative regulation of insulin secretion, ! insulin receptor signaling pathway GO:0008286 40 24 5,000 1,367E-08 3,493E-06 ! regulation of protein export from nucleus GO:0046825 6 6 3,000 3,577E-08 8,228E-06 ! response to hypoxia GO:0001666 132 72 7,000 4,178E-08 8,735E-06 ! negative regulation of transport GO:0051051 116 73 7,000 4,664E-08 8,939E-06 ! negative regulation of hormone secretion GO:0046888 20 15 4,000 4,697E-08 8,31E-06 ! response to oxygen levels GO:0070482 137 74 7,000 5,199E-08 8,541E-06 ! negative regulation of secretion GO:0051048 49 31 5,000 7,18E-08 1,101E-05 ! regulation of growth hormone secretion GO:0060123 11 7 3,000 8,301E-08 1,193E-05 ! positive regulation of hormone secretion GO:0046887 24 17 4,000 9,569E-08 1,295E-05 ! DNA integrity checkpoint GO:0031570 57 34 5,000 1,289E-07 1,647E-05 ! cellular response to insulin stimulus GO:0032869 52 34 5,000 1,289E-07 1,56E-05 ! response to peptide hormone stimulus GO:0043434 84 57 6,000 1,501E-07 1,726E-05 ! induction of positive chemotaxis GO:0050930 14 8 3,000 1,651E-07 1,808E-05 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 3,000 1,651E-07 1,726E-05 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 3,000 1,651E-07 1,651E-05 ! cell cycle checkpoint GO:0000075 108 64 6,000 3,384E-07 3,243E-05 ! negative regulation of phosphorylation GO:0042326 41 23 4,000 5,029E-07 4,627E-05 ! response to insulin stimulus GO:0032868 63 43 5,000 5,546E-07 4,906E-05 ! positive regulation of cell cycle GO:0045787 77 45 5,000 7,324E-07 6,239E-05 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 7,657E-07 6,289E-05 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of phosphorus metabolic process GO:0010563 45 25 4,000 7,851E-07 6,227E-05 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 39 25 4,000 7,851E-07 6,019E-05 GO:0045840|positive regulation of mitosis, ! regulation of angiogenesis GO:0045765 94 49 5,000 1,229E-06 9,116E-05 ! regulation of multicellular organism growth GO:0040014 65 50 5,000 1,388E-06 9,977E-05 ! cell junction assembly GO:0034329 56 28 4,000 1,428E-06 9,951E-05 ! triglyceride metabolic process GO:0006641 34 28 4,000 1,428E-06 9,658E-05 ! regulation of cell cycle process GO:0010564 122 81 6,000 1,715E-06 1,127E-04 ! regulation of mitosis GO:0007088 84 54 5,000 2,205E-06 1,408E-04 GO:0051783|regulation of nuclear division, ! negative regulation of blood coagulation GO:0030195 19 14 3,000 2,284E-06 1,42E-04 ! negative regulation of multicellular organismal process GO:0051241 133 85 6,000 2,378E-06 1,439E-04 ! DNA damage checkpoint GO:0000077 53 31 4,000 2,427E-06 1,431E-04 ! neutral lipid metabolic process GO:0006638 41 32 4,000 2,86E-06 1,644E-04 GO:0006639|acylglycerol metabolic process, ! cell junction organization GO:0034330 63 33 4,000 3,351E-06 1,88E-04 ! carbohydrate homeostasis GO:0033500 39 33 4,000 3,351E-06 1,835E-04 GO:0042593|glucose homeostasis, ! regulation of mitochondrial membrane permeability GO:0046902 9 5 2,000 3,447E-06 1,844E-04 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 4,000 3,907E-06 2,042E-04 ! glycerol ether metabolic process GO:0006662 44 34 4,000 3,907E-06 1,997E-04 ! neutrophil chemotaxis GO:0030593 21 16 3,000 4,108E-06 2,054E-04 ! regulation of hormone secretion GO:0046883 48 36 4,000 5,234E-06 2,561E-04 ! organic ether metabolic process GO:0018904 46 36 4,000 5,234E-06 2,508E-04 ! cell-substrate junction assembly GO:0007044 39 17 3,000 5,343E-06 2,508E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 3,000 5,343E-06 2,458E-04 ! negative regulation of coagulation GO:0050819 23 17 3,000 5,343E-06 2,41E-04 ! regulation of response to external stimulus GO:0032101 139 96 6,000 5,384E-06 2,381E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 5,000 5,506E-06 2,389E-04 ! wound healing, spreading of epidermal cells GO:0035313 10 6 2,000 6,859E-06 2,921E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 8,93E-06 3,734E-04 ! positive regulation of phosphorylation GO:0042327 102 70 5,000 1,02E-05 4,191E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 3,000 1,07E-05 4,317E-04 ! positive regulation of locomotion GO:0040017 35 20 3,000 1,07E-05 4,243E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! branching morphogenesis of a tube GO:0048754 72 42 4,000 1,141E-05 4,45E-04 ! regulation of smooth muscle cell migration GO:0014910 19 7 2,000 1,194E-05 4,577E-04 ! fibrinolysis GO:0042730 9 7 2,000 1,194E-05 4,502E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,194E-05 4,429E-04 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 5,000 1,202E-05 4,388E-04 GO:0045937|positive regulation of phosphate metabolic process, ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 1,284E-05 4,616E-04 ! regulation of chemotaxis GO:0050920 36 21 3,000 1,314E-05 4,651E-04 ! regulation of insulin secretion GO:0050796 26 21 3,000 1,314E-05 4,58E-04 ! regulation of behavior GO:0050795 38 22 3,000 1,598E-05 5,484E-04 ! regulation of blood coagulation GO:0030193 34 22 3,000 1,598E-05 5,404E-04 ! response to UV GO:0009411 75 46 4,000 1,798E-05 5,994E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 1,901E-05 6,245E-04 ! middle ear morphogenesis GO:0042474 9 8 2,000 1,901E-05 6,157E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 1,901E-05 6,071E-04 ! positive regulation of endothelial cell migration GO:0010595 18 8 2,000 1,901E-05 5,988E-04 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 1,901E-05 5,907E-04 ! morphogenesis of a branching structure GO:0001763 86 49 4,000 2,459E-05 7,542E-04 ! regulation of peptide secretion GO:0002791 34 25 3,000 2,718E-05 8,225E-04 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 2,000 2,836E-05 8,471E-04 GO:0010469|regulation of receptor activity, ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 2,836E-05 8,363E-04 ! positive regulation of secretion GO:0051047 71 51 4,000 2,995E-05 8,721E-04 ! positive regulation of organelle organization GO:0010638 82 51 4,000 2,995E-05 8,612E-04 ! regulation of protein localization GO:0032880 132 85 5,000 3,121E-05 8,862E-04 ! regulation of membrane potential GO:0042391 128 85 5,000 3,121E-05 8,754E-04 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 3,000 3,194E-05 8,852E-04 ! regulation of coagulation GO:0050818 39 26 3,000 3,194E-05 8,746E-04 ! regulation of B cell proliferation GO:0030888 15 10 2,000 4,03E-05 1,091E-03 ! DNA damage response, signal transduction GO:0042770 96 56 4,000 4,735E-05 1,266E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 5,161E-05 1,364E-03 ! multicellular organism reproduction GO:0032504 83 57 4,000 5,161E-05 1,349E-03 GO:0048609|reproductive process in a multicellular organism, ! focal adhesion formation GO:0048041 24 11 2,000 5,513E-05 1,425E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 5,513E-05 1,409E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 5,513E-05 1,393E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 5,513E-05 1,378E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of kinase activity GO:0033673 100 58 4,000 5,616E-05 1,389E-03 ! leukocyte chemotaxis GO:0030595 43 31 3,000 6,541E-05 1,601E-03 GO:0060326|cell chemotaxis, ! regulation of heart contraction GO:0008016 91 60 4,000 6,619E-05 1,602E-03 ! cell-matrix adhesion GO:0007160 114 61 4,000 7,169E-05 1,718E-03 ! negative regulation of transferase activity GO:0051348 105 61 4,000 7,169E-05 1,7E-03 ! negative regulation of cell growth GO:0030308 106 62 4,000 7,754E-05 1,82E-03 ! nucleus organization GO:0006997 49 33 3,000 8,414E-05 1,955E-03 ! negative regulation of cell size GO:0045792 108 64 4,000 9,033E-05 2,078E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 9,458E-05 2,154E-03 ! cell-substrate adhesion GO:0031589 121 66 4,000 1,047E-04 2,361E-03 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 1,065E-04 2,378E-03 ! hormone-mediated signaling GO:0009755 49 36 3,000 1,191E-04 2,635E-03 ! negative regulation of bone remodeling GO:0046851 26 14 2,000 1,197E-04 2,623E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 2,000 1,197E-04 2,598E-03 GO:0060675|ureteric bud morphogenesis, ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 2,000 1,489E-04 3,201E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,489E-04 3,171E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 1,489E-04 3,142E-03 ! negative regulation of tissue remodeling GO:0034104 27 15 2,000 1,489E-04 3,114E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 1,489E-04 3,085E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 2,000 1,489E-04 3,058E-03 ! tube morphogenesis GO:0035239 118 73 4,000 1,691E-04 3,443E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 1,809E-04 3,649E-03 ! negative regulation of growth GO:0045926 123 75 4,000 1,922E-04 3,844E-03 ! regulation of protein transport GO:0051223 114 76 4,000 2,046E-04 4,056E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 2,191E-04 4,307E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,202E-04 4,293E-03 ! negative regulation of homeostatic process GO:0032845 28 17 2,000 2,202E-04 4,257E-03 ! leukocyte migration GO:0050900 60 43 3,000 2,402E-04 4,605E-03 ! negative regulation of cell migration GO:0030336 92 44 3,000 2,628E-04 4,996E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 2,628E-04 4,955E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 2,629E-04 4,917E-03 ! response to retinoic acid GO:0032526 25 18 2,000 2,629E-04 4,877E-03 ! regulation of glucose import GO:0046324 21 18 2,000 2,629E-04 4,838E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 25 18 2,000 2,629E-04 4,8E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 2,869E-04 5,196E-03 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 3,106E-04 5,581E-03 ! renal system process GO:0003014 35 19 2,000 3,106E-04 5,538E-03 ! negative regulation of angiogenesis GO:0016525 36 19 2,000 3,106E-04 5,496E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 3,106E-04 5,454E-03 ! response to vitamin A GO:0033189 26 19 2,000 3,106E-04 5,412E-03 ! apoptotic nuclear changes GO:0030262 24 19 2,000 3,106E-04 5,372E-03 ! plasma membrane fusion GO:0045026 23 19 2,000 3,106E-04 5,331E-03 ! regulation of endothelial cell migration GO:0010594 40 19 2,000 3,106E-04 5,292E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 3,397E-04 5,745E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to vitamin GO:0033273 29 20 2,000 3,635E-04 6,103E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 3,635E-04 6,059E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 3,645E-04 6,031E-03 ! regulation of muscle contraction GO:0006937 69 48 3,000 3,686E-04 6,055E-03 ! regulation of intracellular transport GO:0032386 78 49 3,000 3,992E-04 6,511E-03 ! cartilage development GO:0051216 70 49 3,000 3,992E-04 6,465E-03 ! interphase GO:0051325 159 88 4,000 4,054E-04 6,52E-03 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 4,219E-04 6,739E-03 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 4,219E-04 6,693E-03 ! regulation of vasoconstriction GO:0019229 31 21 2,000 4,219E-04 6,647E-03 ! response to cytokine stimulus GO:0034097 47 21 2,000 4,219E-04 6,602E-03 ! ear development GO:0043583 72 50 3,000 4,315E-04 6,706E-03 ! positive regulation of growth GO:0045927 67 50 3,000 4,315E-04 6,661E-03 ! hormone metabolic process GO:0042445 121 90 4,000 4,497E-04 6,895E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 4,657E-04 7,093E-03 ! activation of phospholipase C activity GO:0007202 87 51 3,000 4,657E-04 7,046E-03 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cell motion GO:0051271 104 51 3,000 4,657E-04 7E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 4,86E-04 7,259E-03 GO:0010810|regulation of cell-substrate adhesion, ! ureteric bud development GO:0001657 32 22 2,000 4,86E-04 7,212E-03 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 1,000 4,921E-04 7,256E-03 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,921E-04 7,21E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 4,921E-04 7,164E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 4,921E-04 7,119E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 4,921E-04 7,075E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 4,921E-04 7,031E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 1,000 4,921E-04 6,987E-03 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 4,921E-04 6,944E-03 ! microvillus organization GO:0032528 7 5 1,000 4,921E-04 6,902E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 1,000 4,921E-04 6,86E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 1,000 4,921E-04 6,819E-03 ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 4,921E-04 6,778E-03 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 4,921E-04 6,738E-03 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 4,921E-04 6,698E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 4,921E-04 6,658E-03 ! triglyceride catabolic process GO:0019433 6 5 1,000 4,921E-04 6,62E-03 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 4,921E-04 6,581E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 4,921E-04 6,543E-03 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 4,921E-04 6,505E-03 ! positive regulation of phospholipase activity GO:0010518 88 52 3,000 5,017E-04 6,594E-03 ! peptidyl-amino acid modification GO:0018193 147 93 4,000 5,229E-04 6,833E-03 ! myelination GO:0042552 35 23 2,000 5,561E-04 7,226E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 5,561E-04 7,185E-03 ! angiogenesis GO:0001525 149 95 4,000 5,764E-04 7,406E-03 ! regulation of phospholipase activity GO:0010517 90 54 3,000 5,797E-04 7,408E-03 ! positive regulation of lipase activity GO:0060193 90 54 3,000 5,797E-04 7,367E-03 ! response to light stimulus GO:0009416 153 96 4,000 6,046E-04 7,641E-03 ! mitochondrial membrane organization GO:0007006 39 24 2,000 6,322E-04 7,946E-03 ! response to toxin GO:0009636 38 24 2,000 6,322E-04 7,903E-03 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 7,147E-04 8,886E-03 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 7,147E-04 8,838E-03 ! regulation of body fluid levels GO:0050878 154 100 4,000 7,282E-04 8,956E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 7,348E-04 8,989E-03 ! mRNA stabilization GO:0048255 15 6 1,000 7,348E-04 8,942E-03 GO:0043489|RNA stabilization, ! inositol phosphate-mediated signaling GO:0048016 9 6 1,000 7,348E-04 8,895E-03 ! pigment granule organization GO:0048753 11 6 1,000 7,348E-04 8,848E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 7,348E-04 8,802E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! vascular smooth muscle contraction GO:0014829 10 6 1,000 7,348E-04 8,757E-03 ! positive regulation of muscle hypertrophy GO:0014742 9 6 1,000 7,348E-04 8,711E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 7,348E-04 8,667E-03 ! maintenance of protein location in nucleus GO:0051457 16 6 1,000 7,348E-04 8,623E-03 ! glycerol ether catabolic process GO:0044269 8 6 1,000 7,348E-04 8,579E-03 GO:0046464|acylglycerol catabolic process, ! neuron apoptosis GO:0051402 8 6 1,000 7,348E-04 8,535E-03 ! male sex determination GO:0030238 9 6 1,000 7,348E-04 8,493E-03 ! purine base biosynthetic process GO:0009113 14 6 1,000 7,348E-04 8,45E-03 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 7,348E-04 8,408E-03 ! progesterone metabolic process GO:0042448 8 6 1,000 7,348E-04 8,366E-03 ! positive regulation of smooth muscle contraction GO:0045987 9 6 1,000 7,348E-04 8,325E-03 ! negative regulation of B cell activation GO:0050869 9 6 1,000 7,348E-04 8,284E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 7,348E-04 8,244E-03 ! negative regulation of protein modification process GO:0031400 50 26 2,000 8,038E-04 8,974E-03 ! response to ionizing radiation GO:0010212 47 27 2,000 8,996E-04 9,996E-03 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 8,996E-04 9,947E-03 ! positive regulation of multicellular organism growth GO:0040018 38 28 2,000 1,002E-03 0,01103071 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,002E-03 0,01097819 ! ensheathment of neurons GO:0007272 43 28 2,000 1,002E-03 0,01092616 GO:0008366|axon ensheathment, ! regulation of B cell activation GO:0050864 42 28 2,000 1,002E-03 0,01087462 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,024E-03 0,01105658 ! neutral lipid catabolic process GO:0046461 9 7 1,000 1,024E-03 0,01100491 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 1,024E-03 0,01095372 ! T-helper 1 type immune response GO:0042088 11 7 1,000 1,024E-03 0,01090301 ! positive regulation of heart rate GO:0010460 9 7 1,000 1,024E-03 0,01085277 ! glycerolipid catabolic process GO:0046503 9 7 1,000 1,024E-03 0,01080298 ! regulation of granule cell precursor proliferation GO:0021936 11 7 1,000 1,024E-03 0,01075366 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of pigmentation during development GO:0048070 15 7 1,000 1,024E-03 0,01070478 ! phasic smooth muscle contraction GO:0014821 12 7 1,000 1,024E-03 0,01065634 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 1,024E-03 0,01060834 ! behavioral fear response GO:0001662 13 7 1,000 1,024E-03 0,01056077 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 10 7 1,000 1,024E-03 0,01051362 ! response to UV-B GO:0010224 11 7 1,000 1,024E-03 0,01046689 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 1,024E-03 0,01042058 ! B cell lineage commitment GO:0002326 17 7 1,000 1,024E-03 0,01037467 ! T cell lineage commitment GO:0002360 12 7 1,000 1,024E-03 0,01032917 ! peptidyl-threonine modification GO:0018210 18 7 1,000 1,024E-03 0,01028406 ! diuresis GO:0030146 12 7 1,000 1,024E-03 0,01023935 GO:0030147|natriuresis, ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 1,024E-03 0,01019502 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 1,000 1,024E-03 0,01015108 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 1,000 1,024E-03 0,01010751 ! regulation of lipase activity GO:0060191 109 63 3,000 1,04E-03 0,01021922 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 3,000 1,103E-03 0,01079518 ! embryonic skeletal system morphogenesis GO:0048704 42 30 2,000 1,229E-03 0,01198214 ! hindbrain development GO:0030902 45 30 2,000 1,229E-03 0,01193158 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,229E-03 0,01188145 ! mammary gland development GO:0030879 57 31 2,000 1,354E-03 0,01303197 ! regulation of striated muscle tissue development GO:0016202 47 31 2,000 1,354E-03 0,01297767 ! metanephros development GO:0001656 58 31 2,000 1,354E-03 0,01292382 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 1,359E-03 0,01291528 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,359E-03 0,01286213 ! succinate metabolic process GO:0006105 14 8 1,000 1,359E-03 0,01280941 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 1,359E-03 0,01275713 ! melanin metabolic process GO:0006582 12 8 1,000 1,359E-03 0,01270527 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 1,359E-03 0,01265383 ! regulation of muscle hypertrophy GO:0014743 11 8 1,000 1,359E-03 0,01260281 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of vascular permeability GO:0043114 12 8 1,000 1,359E-03 0,0125522 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,359E-03 0,01250199 ! regulation of embryonic development GO:0045995 16 8 1,000 1,359E-03 0,01245218 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 1,359E-03 0,01240276 GO:0000076|DNA replication checkpoint, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 1,359E-03 0,01235374 ! activation of protein kinase activity GO:0032147 102 69 3,000 1,46E-03 0,01322458 ! regulation of muscle development GO:0048634 48 32 2,000 1,487E-03 0,01340846 ! mitotic sister chromatid segregation GO:0000070 45 32 2,000 1,487E-03 0,01335608 ! regulation of protein stability GO:0031647 48 32 2,000 1,487E-03 0,01330411 ! calcium-mediated signaling GO:0019722 50 32 2,000 1,487E-03 0,01325254 ! phosphoinositide-mediated signaling GO:0048015 109 71 3,000 1,624E-03 0,01441884 ! sister chromatid segregation GO:0000819 46 33 2,000 1,627E-03 0,01439123 ! ear morphogenesis GO:0042471 42 33 2,000 1,627E-03 0,01433609 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 1,000 1,739E-03 0,01526664 ! regulation of developmental growth GO:0048638 13 9 1,000 1,739E-03 0,01520859 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 1,739E-03 0,01515098 ! regulation of glycolysis GO:0006110 15 9 1,000 1,739E-03 0,01509381 ! lung alveolus development GO:0048286 17 9 1,000 1,739E-03 0,01503706 ! T cell selection GO:0045058 18 9 1,000 1,739E-03 0,01498074 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,739E-03 0,01492485 GO:0006600|creatine metabolic process, ! positive regulation of muscle contraction GO:0045933 12 9 1,000 1,739E-03 0,01486936 ! motor axon guidance GO:0008045 14 9 1,000 1,739E-03 0,01481429 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 1,739E-03 0,01475963 ! renal water homeostasis GO:0003091 14 9 1,000 1,739E-03 0,01470536 ! regulation of DNA replication initiation GO:0030174 13 9 1,000 1,739E-03 0,0146515 ! purine base metabolic process GO:0006144 18 9 1,000 1,739E-03 0,01459802 ! oocyte differentiation GO:0009994 12 9 1,000 1,739E-03 0,01454494 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 1,000 1,739E-03 0,01449224 ! spleen development GO:0048536 15 9 1,000 1,739E-03 0,01443992 ! regulation of muscle adaptation GO:0043502 12 9 1,000 1,739E-03 0,01438798 ! response to nicotine GO:0035094 16 9 1,000 1,739E-03 0,01433641 ! localization within membrane GO:0051668 15 9 1,000 1,739E-03 0,01428521 ! dorsal/ventral pattern formation GO:0009953 44 34 2,000 1,775E-03 0,01452922 ! mitochondrion organization GO:0007005 104 73 3,000 1,799E-03 0,01467428 ! regulation of action potential in neuron GO:0019228 54 35 2,000 1,932E-03 0,0156979 ! pigment metabolic process GO:0042440 61 35 2,000 1,932E-03 0,01564262 ! blood coagulation GO:0007596 116 75 3,000 1,987E-03 0,01603904 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 3,000 1,987E-03 0,01598296 ! response to reactive oxygen species GO:0000302 55 36 2,000 2,096E-03 0,0167995 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 2,164E-03 0,01728003 ! hair follicle morphogenesis GO:0031069 17 10 1,000 2,164E-03 0,01722024 ! blood vessel remodeling GO:0001974 21 10 1,000 2,164E-03 0,01716086 ! positive regulation of heart contraction GO:0045823 14 10 1,000 2,164E-03 0,01710188 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,164E-03 0,01704332 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,164E-03 0,01698515 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 2,164E-03 0,01692737 ! B cell proliferation GO:0042100 14 10 1,000 2,164E-03 0,01686999 ! nucleobase biosynthetic process GO:0046112 21 10 1,000 2,164E-03 0,016813 ! fear response GO:0042596 16 10 1,000 2,164E-03 0,01675639 ! negative regulation of ossification GO:0030279 19 10 1,000 2,164E-03 0,01670016 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 2,164E-03 0,01664431 ! regulation of bone resorption GO:0045124 24 10 1,000 2,164E-03 0,01658883 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,164E-03 0,01653371 ! cranial nerve development GO:0021545 12 10 1,000 2,164E-03 0,01647897 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 2,164E-03 0,01642458 ! multicellular organismal water homeostasis GO:0050891 15 10 1,000 2,164E-03 0,01637055 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 2,164E-03 0,01631688 GO:0043470|regulation of carbohydrate catabolic process, ! gland development GO:0048732 148 77 3,000 2,189E-03 0,01645256 ! positive regulation of protein modification process GO:0031401 107 78 3,000 2,295E-03 0,0171918 ! regulation of T cell proliferation GO:0042129 58 38 2,000 2,451E-03 0,01830592 ! mesenchymal cell development GO:0014031 64 38 2,000 2,451E-03 0,01824667 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! virus-host interaction GO:0019048 17 11 1,000 2,632E-03 0,01953029 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,632E-03 0,0194675 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 2,632E-03 0,0194051 ! vasoconstriction GO:0042310 15 11 1,000 2,632E-03 0,0193431 ! T cell homeostasis GO:0043029 20 11 1,000 2,632E-03 0,0192815 ! regulation of leukocyte migration GO:0002685 24 11 1,000 2,632E-03 0,01922029 ! digestive tract morphogenesis GO:0048546 15 11 1,000 2,632E-03 0,01915947 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! hemostasis GO:0007599 125 81 3,000 2,633E-03 0,01910584 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 2,000 2,642E-03 0,01910914 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 2,642E-03 0,01904924 ! chromatin remodeling GO:0006338 68 39 2,000 2,642E-03 0,01898971 ! regulation of cell adhesion GO:0030155 159 83 3,000 2,877E-03 0,0206148 ! glucose transport GO:0015758 52 41 2,000 3,05E-03 0,02178717 ! regulation of T cell differentiation GO:0045580 59 41 2,000 3,05E-03 0,02171972 ! regulation of JNK cascade GO:0046328 58 41 2,000 3,05E-03 0,02165268 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 3,144E-03 0,02225117 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 3,144E-03 0,02218291 ! cell-cell junction assembly GO:0007043 18 12 1,000 3,144E-03 0,02211508 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 3,144E-03 0,02204765 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 3,144E-03 0,02198064 ! histone methylation GO:0016571 15 12 1,000 3,144E-03 0,02191403 ! autonomic nervous system development GO:0048483 23 12 1,000 3,144E-03 0,02184783 ! gland morphogenesis GO:0022612 23 12 1,000 3,144E-03 0,02178202 ! peptidyl-lysine modification GO:0018205 18 12 1,000 3,144E-03 0,02171661 ! response to gamma radiation GO:0010332 20 12 1,000 3,144E-03 0,02165159 ! cAMP biosynthetic process GO:0006171 20 12 1,000 3,144E-03 0,02158696 ! regulation of mRNA stability GO:0043488 27 12 1,000 3,144E-03 0,02152271 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 3,144E-03 0,02145884 ! mitochondrial transport GO:0006839 60 42 2,000 3,268E-03 0,02223775 ! cellular component disassembly GO:0022411 64 42 2,000 3,268E-03 0,02217215 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 2,000 3,268E-03 0,02210694 ! hexose transport GO:0008645 54 42 2,000 3,268E-03 0,02204211 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 2,000 3,268E-03 0,02197766 ! regulation of cell shape GO:0008360 78 42 2,000 3,268E-03 0,02191358 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 3,495E-03 0,02336815 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 3,699E-03 0,02465775 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 1,000 3,699E-03 0,02458648 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 3,699E-03 0,02451563 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,699E-03 0,02444518 ! cellular pigmentation GO:0033059 24 13 1,000 3,699E-03 0,02437514 ! regulation of RNA stability GO:0043487 28 13 1,000 3,699E-03 0,02430549 ! lymphocyte homeostasis GO:0002260 24 13 1,000 3,699E-03 0,02423625 ! regulation of action potential GO:0001508 71 44 2,000 3,732E-03 0,0243824 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 3,732E-03 0,02431333 ! regulation of inflammatory response GO:0050727 60 44 2,000 3,732E-03 0,02424465 ! positive regulation of defense response GO:0031349 59 45 2,000 3,978E-03 0,02577047 ! vascular process in circulatory system GO:0003018 69 45 2,000 3,978E-03 0,02569808 ! cell fate commitment GO:0045165 141 92 3,000 4,167E-03 0,0268432 ! histone modification GO:0016570 68 46 2,000 4,233E-03 0,02719731 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 4,295E-03 0,02751766 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,295E-03 0,02744122 ! heterophilic cell adhesion GO:0007157 29 14 1,000 4,295E-03 0,02736521 ! activation of MAPKK activity GO:0000186 21 14 1,000 4,295E-03 0,02728961 ! epidermis morphogenesis GO:0048730 29 14 1,000 4,295E-03 0,02721444 ! regulation of heart rate GO:0002027 23 14 1,000 4,295E-03 0,02713967 ! G1/S transition checkpoint GO:0031575 33 14 1,000 4,295E-03 0,02706532 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 1,000 4,295E-03 0,02699137 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! T cell differentiation in the thymus GO:0033077 27 14 1,000 4,295E-03 0,02691782 ! water homeostasis GO:0030104 24 14 1,000 4,295E-03 0,02684467 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 1,000 4,295E-03 0,02677192 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 4,295E-03 0,02669957 ! peptide hormone secretion GO:0030072 23 14 1,000 4,295E-03 0,0266276 ! covalent chromatin modification GO:0016569 75 47 2,000 4,499E-03 0,02781513 ! negative regulation of immune system process GO:0002683 73 47 2,000 4,499E-03 0,02774055 ! regulation of binding GO:0051098 151 95 3,000 4,671E-03 0,02872379 ! regulation of DNA replication GO:0006275 75 48 2,000 4,774E-03 0,0292814 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 4,774E-03 0,02920353 ! positive regulation of cell size GO:0045793 20 15 1,000 4,933E-03 0,03009542 ! metencephalon development GO:0022037 19 15 1,000 4,933E-03 0,0300158 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 4,933E-03 0,0299366 ! lipid phosphorylation GO:0046834 23 15 1,000 4,933E-03 0,02985782 ! regulation of muscle cell differentiation GO:0051147 24 15 1,000 4,933E-03 0,02977945 ! regulation of survival gene product expression GO:0045884 20 15 1,000 4,933E-03 0,0297015 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 4,933E-03 0,02962395 ! peptide secretion GO:0002790 27 15 1,000 4,933E-03 0,0295468 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 2,000 5,059E-03 0,03022539 ! membrane fusion GO:0006944 80 50 2,000 5,355E-03 0,03190725 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 3,000 5,405E-03 0,03212121 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 5,612E-03 0,03326525 ! hormone secretion GO:0046879 25 16 1,000 5,612E-03 0,03317974 ! protein amino acid acetylation GO:0006473 28 16 1,000 5,612E-03 0,03309466 ! patterning of blood vessels GO:0001569 24 16 1,000 5,612E-03 0,03301002 ! mitotic chromosome condensation GO:0007076 25 16 1,000 5,612E-03 0,03292581 ! regulation of protein binding GO:0043393 27 16 1,000 5,612E-03 0,03284203 ! DNA replication initiation GO:0006270 25 16 1,000 5,612E-03 0,03275868 ! oogenesis GO:0048477 23 16 1,000 5,612E-03 0,03267574 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 5,612E-03 0,03259323 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 5,612E-03 0,03251113 ! nerve development GO:0021675 18 16 1,000 5,612E-03 0,03242944 ! negative regulation of translation GO:0017148 22 16 1,000 5,612E-03 0,03234817 ! aging GO:0007568 79 52 2,000 5,976E-03 0,03436362 ! regulation of bone remodeling GO:0046850 90 53 2,000 6,302E-03 0,03614886 ! skeletal system morphogenesis GO:0048705 78 53 2,000 6,302E-03 0,03605894 ! kidney development GO:0001822 90 53 2,000 6,302E-03 0,03596946 ! signal complex assembly GO:0007172 29 17 1,000 6,331E-03 0,03604034 ! memory GO:0007613 25 17 1,000 6,331E-03 0,03595136 ! regulation of viral genome replication GO:0045069 24 17 1,000 6,331E-03 0,0358628 ! actin filament bundle formation GO:0051017 26 17 1,000 6,331E-03 0,03577469 ! neuromuscular junction development GO:0007528 23 17 1,000 6,331E-03 0,03568701 ! body fluid secretion GO:0007589 27 17 1,000 6,331E-03 0,03559975 ! nucleobase metabolic process GO:0009112 31 17 1,000 6,331E-03 0,03551292 ! peptidyl-serine modification GO:0018209 27 17 1,000 6,331E-03 0,03542652 ! cell-cell junction organization GO:0045216 25 17 1,000 6,331E-03 0,03534053 ! DNA catabolic process GO:0006308 67 54 2,000 6,639E-03 0,03697323 ! regulation of tissue remodeling GO:0034103 91 54 2,000 6,639E-03 0,03688392 ! mesoderm development GO:0007498 76 55 2,000 6,986E-03 0,03871901 ! positive regulation of DNA replication GO:0045740 29 18 1,000 7,089E-03 0,0391941 ! cAMP metabolic process GO:0046058 33 18 1,000 7,089E-03 0,03910011 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 1,000 7,089E-03 0,03900656 GO:0050886|endocrine process, ! glutamine metabolic process GO:0006541 23 18 1,000 7,089E-03 0,03891347 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 7,089E-03 0,03882082 ! peptide cross-linking GO:0018149 31 18 1,000 7,089E-03 0,03872861 ! somitogenesis GO:0001756 24 18 1,000 7,089E-03 0,03863683 ! hormone transport GO:0009914 27 18 1,000 7,089E-03 0,03854549 ! gut development GO:0048565 26 18 1,000 7,089E-03 0,03845458 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 7,089E-03 0,0383641 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 7,344E-03 0,03965074 ! carbohydrate transport GO:0008643 74 57 2,000 7,712E-03 0,04154237 ! chromosome segregation GO:0007059 83 57 2,000 7,712E-03 0,0414453 ! secondary metabolic process GO:0019748 84 57 2,000 7,712E-03 0,0413487 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 7,886E-03 0,04218349 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 7,886E-03 0,04208562 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 7,886E-03 0,04198819 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 7,886E-03 0,04189122 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 23 19 1,000 7,886E-03 0,0417947 ! regeneration GO:0031099 32 19 1,000 7,886E-03 0,04169862 ! response to alkaloid GO:0043279 32 19 1,000 7,886E-03 0,04160298 ! smooth muscle contraction GO:0006939 36 19 1,000 7,886E-03 0,04150778 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 7,886E-03 0,04141301 ! sex determination GO:0007530 29 19 1,000 7,886E-03 0,04131868 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 2,000 8,482E-03 0,04433555 ! lung development GO:0030324 94 59 2,000 8,482E-03 0,04423502 ! actin filament organization GO:0007015 95 59 2,000 8,482E-03 0,04413494 ! nucleoside monophosphate metabolic process GO:0009123 95 59 2,000 8,482E-03 0,04403531 ! response to ethanol GO:0045471 37 20 1,000 8,722E-03 0,0451834 ! multicellular organismal response to stress GO:0033555 32 20 1,000 8,722E-03 0,04508186 ! chromosome condensation GO:0030261 31 20 1,000 8,722E-03 0,04498078 ! positive regulation of B cell activation GO:0050871 31 20 1,000 8,722E-03 0,04488015 ! regulation of homeostatic process GO:0032844 105 60 2,000 8,882E-03 0,04560186 ! regulation of cellular response to stress GO:0080135 85 61 2,000 9,294E-03 0,04760978 ! urogenital system development GO:0001655 101 61 2,000 9,294E-03 0,04750398 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 9,596E-03 0,04893792 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 9,596E-03 0,04882965 ! protein amino acid acylation GO:0043543 37 21 1,000 9,596E-03 0,04872186 ! ovarian follicle development GO:0001541 30 21 1,000 9,596E-03 0,04861454 ! cell aging GO:0007569 32 21 1,000 9,596E-03 0,0485077 ! platelet activation GO:0030168 28 21 1,000 9,596E-03 0,04840132 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 9,596E-03 0,04829541 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 9,596E-03 0,04818996 ! respiratory tube development GO:0030323 99 62 2,000 9,717E-03 0,04869118 ! regulation of transcription factor activity GO:0051090 97 63 2,000 0,01015093 0,05075467 GO:0090046|regulation of transcription regulator activity, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 0,01050709 0,05242151 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01050709 0,05230804 ! spliceosomal snRNP biogenesis GO:0000387 28 22 1,000 0,01050709 0,05219506 ! leukocyte adhesion GO:0007159 38 22 1,000 0,01050709 0,05208257 ! molting cycle process GO:0022404 40 22 1,000 0,01050709 0,05197057 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 0,01050709 0,05185904 ! glutamate signaling pathway GO:0007215 34 22 1,000 0,01050709 0,051748 ! vasculogenesis GO:0001570 33 22 1,000 0,01050709 0,05163742 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 0,01050709 0,05152732 ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 0,01050709 0,05141769 ! membrane depolarization GO:0051899 35 22 1,000 0,01050709 0,05130852 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01050709 0,05119982 ! positive regulation of JUN kinase activity GO:0043507 28 22 1,000 0,01050709 0,05109157 ! protein tetramerization GO:0051262 39 22 1,000 0,01050709 0,05098378 ! respiratory system development GO:0060541 100 64 2,000 0,01059592 0,05130654 ! regulation of MAPKKK cascade GO:0043408 101 65 2,000 0,01105206 0,05340281 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 0,01145481 0,05523284 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01145481 0,05511729 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 0,01145481 0,05500222 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01145481 0,05488763 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01145481 0,05477352 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,01145481 0,05465988 ! interaction with host GO:0051701 37 23 1,000 0,01145481 0,05454672 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,01145481 0,05443402 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,01145481 0,05432178 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 1,000 0,01145481 0,05421001 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 1,000 0,01145481 0,05409869 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! regulation of neuron differentiation GO:0045664 107 67 2,000 0,01199803 0,05654808 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 0,01243868 0,05850505 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 0,01243868 0,05838565 ! neural crest cell development GO:0014032 39 24 1,000 0,01243868 0,05826674 GO:0014033|neural crest cell differentiation, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01243868 0,05814831 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 0,01243868 0,05803036 ! learning or memory GO:0007611 123 68 2,000 0,01248794 0,05814222 ! protein amino acid alkylation GO:0008213 39 25 1,000 0,01345816 0,06253285 GO:0006479|protein amino acid methylation, ! peptide transport GO:0015833 43 25 1,000 0,01345816 0,06240677 ! male gonad development GO:0008584 33 25 1,000 0,01345816 0,06228121 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 1,000 0,01345816 0,06215614 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01345816 0,06203158 ! leukocyte proliferation GO:0070661 39 25 1,000 0,01345816 0,06190752 GO:0032943|mononuclear cell proliferation, ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 0,01402585 0,06439012 ! regulation of pH GO:0006885 36 26 1,000 0,01451269 0,06649239 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 1,000 0,01451269 0,0663602 ! post-embryonic development GO:0009791 42 26 1,000 0,01451269 0,06622853 ! regulation of synaptic transmission GO:0050804 109 72 2,000 0,01456132 0,0663189 ! inner ear morphogenesis GO:0042472 35 27 1,000 0,01560173 0,07091698 ! acute-phase response GO:0006953 42 27 1,000 0,01560173 0,0707771 ! respiratory gaseous exchange GO:0007585 47 27 1,000 0,01560173 0,07063777 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01560173 0,070499 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,01560173 0,07036076 ! regulation of ligase activity GO:0051340 114 75 2,000 0,01623669 0,07308099 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01672476 0,07513077 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01672476 0,07498432 ! regulation of systemic arterial blood pressure GO:0003073 47 28 1,000 0,01672476 0,07483844 ! mesoderm formation GO:0001707 46 28 1,000 0,01672476 0,07469312 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01672476 0,07454837 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 0,0168182 0,07481986 ! regulation of DNA binding GO:0051101 119 77 2,000 0,01741128 0,07730879 ! regulation of transmission of nerve impulse GO:0051969 116 77 2,000 0,01741128 0,07715983 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,01788125 0,07909013 ! ovulation cycle process GO:0022602 41 29 1,000 0,01788125 0,07893832 ! formation of primary germ layer GO:0001704 48 29 1,000 0,01788125 0,0787871 ! tissue homeostasis GO:0001894 42 29 1,000 0,01788125 0,07863645 GO:0048871|multicellular organismal homeostasis, ! T cell activation GO:0042110 134 79 2,000 0,01863221 0,08178258 ! spindle organization GO:0007051 37 30 1,000 0,01907066 0,08354765 ! pigment biosynthetic process GO:0046148 50 30 1,000 0,01907066 0,08338881 ! ovulation cycle GO:0042698 43 30 1,000 0,01907066 0,08323058 ! response to heat GO:0009408 41 30 1,000 0,01907066 0,08307294 ! regulation of neurological system process GO:0031644 122 81 2,000 0,01989957 0,08651986 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 0,02029248 0,08806172 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,02029248 0,08789588 ! segmentation GO:0035282 41 31 1,000 0,02029248 0,08773066 ! mesoderm morphogenesis GO:0048332 49 31 1,000 0,02029248 0,08756606 ! cell fate specification GO:0001708 37 31 1,000 0,02029248 0,08740208 ! ossification GO:0001503 134 82 2,000 0,02055069 0,08834876 GO:0060348|bone development, ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,02154621 0,09245575 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,02154621 0,09228358 ! meiosis I GO:0007127 52 32 1,000 0,02154621 0,09211205 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,02154621 0,09194116 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,02154621 0,09177089 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02154621 0,09160126 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02154621 0,09143226 ! regulation of defense response GO:0031347 117 84 2,000 0,02188785 0,09271097 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 0,0225739 0,0954411 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,0225739 0,09526598 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02283133 0,09617594 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02283133 0,09600011 ! female gonad development GO:0008585 49 33 1,000 0,02283133 0,09582493 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,02283133 0,09565038 ! positive regulation of cell development GO:0010720 54 33 1,000 0,02283133 0,09547647 ! hormone biosynthetic process GO:0042446 45 33 1,000 0,02283133 0,0953032 ! cytokinesis GO:0000910 52 33 1,000 0,02283133 0,09513055 ! cell cycle arrest GO:0007050 150 86 2,000 0,02327159 0,09678959 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,02398092 0,09955977 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 2,000 0,02398092 0,09938038 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,02414735 0,0998901 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,02414735 0,09971076 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,02414735 0,09953207 ! female gamete generation GO:0007292 43 34 1,000 0,02414735 0,09935402 ! regulation of neurogenesis GO:0050767 153 89 2,000 0,0254345 0,10446312 ! reproductive developmental process GO:0003006 127 89 2,000 0,0254345 0,10427691 ! regulation of T cell activation GO:0050863 128 89 2,000 0,0254345 0,10409136 ! cyclic nucleotide metabolic process GO:0009187 58 35 1,000 0,02549376 0,10414857 ! maintenance of protein location GO:0045185 65 35 1,000 0,02549376 0,10396391 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,02549376 0,10377991 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02687008 0,10918938 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,02687008 0,1089968 ! negative regulation of binding GO:0051100 58 36 1,000 0,02687008 0,10880491 ! tissue remodeling GO:0048771 62 36 1,000 0,02687008 0,10861369 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,02687008 0,10842314 GO:0046660|female sex differentiation, ! response to virus GO:0009615 122 91 2,000 0,02693459 0,10849308 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,02827583 0,11369651 ! learning GO:0007612 67 37 1,000 0,02827583 0,11349808 ! regulation of protein secretion GO:0050708 51 37 1,000 0,02827583 0,11330035 ! response to oxidative stress GO:0006979 141 94 2,000 0,02927175 0,117087 ! pigmentation GO:0043473 74 38 1,000 0,02971052 0,11863575 ! maintenance of location in cell GO:0051651 69 38 1,000 0,02971052 0,11843014 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,03117368 0,12404751 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,03117368 0,12383326 ! male sex differentiation GO:0046661 53 39 1,000 0,03117368 0,12361976 ! JNK cascade GO:0007254 54 39 1,000 0,03117368 0,12340699 ! developmental growth GO:0048589 62 39 1,000 0,03117368 0,12319495 ! synapse organization GO:0050808 55 39 1,000 0,03117368 0,12298364 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,03266484 0,12864577 ! regulation of tube size GO:0035150 60 40 1,000 0,03266484 0,12842587 GO:0050880|regulation of blood vessel size, ! peptide metabolic process GO:0006518 56 40 1,000 0,03266484 0,12820671 ! inner ear development GO:0048839 57 40 1,000 0,03266484 0,1279883 ! T cell differentiation GO:0030217 65 40 1,000 0,03266484 0,12777063 ! B cell differentiation GO:0030183 62 40 1,000 0,03266484 0,1275537 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,03266484 0,12733751 ! endosome transport GO:0016197 71 41 1,000 0,03418354 0,13303239 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03418354 0,13280767 ! biopolymer methylation GO:0043414 62 41 1,000 0,03418354 0,13258371 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03496944 0,13540356 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03496944 0,13517599 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03496944 0,13494919 ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03496944 0,13472314 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03496944 0,13449785 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03496944 0,13427332 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03496944 0,13404953 ! sleep GO:0030431 11 5 0,000 0,03496944 0,13382648 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03496944 0,13360418 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03496944 0,13338261 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03496944 0,13316178 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03496944 0,13294168 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03496944 0,1327223 ! tongue development GO:0043586 6 5 0,000 0,03496944 0,13250365 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03496944 0,13228572 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03496944 0,1320685 ! cobalt ion transport GO:0006824 9 5 0,000 0,03496944 0,13185199 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03496944 0,1316362 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03496944 0,13142111 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03496944 0,13120672 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03496944 0,13099302 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03496944 0,13078003 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03496944 0,13056772 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03496944 0,1303561 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03496944 0,13014517 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03496944 0,12993492 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03496944 0,12972535 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03496944 0,12951645 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03496944 0,12930823 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03496944 0,12910067 ! malate metabolic process GO:0006108 7 5 0,000 0,03496944 0,12889378 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03496944 0,12868755 ! behavioral response to pain GO:0048266 7 5 0,000 0,03496944 0,12848197 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03496944 0,12827706 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03496944 0,1280728 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03496944 0,12786918 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03496944 0,12766622 ! mating behavior GO:0007617 6 5 0,000 0,03496944 0,12746389 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03496944 0,12726221 ! rhythmic behavior GO:0007622 12 5 0,000 0,03496944 0,12706116 ! copulation GO:0007620 7 5 0,000 0,03496944 0,12686075 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03496944 0,12666097 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03496944 0,12646182 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03496944 0,12626329 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03496944 0,12606539 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03496944 0,1258681 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03496944 0,12567143 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03496944 0,12547538 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03496944 0,12527993 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03496944 0,1250851 ! response to protozoan GO:0001562 9 5 0,000 0,03496944 0,12489086 ! lymph vessel development GO:0001945 7 5 0,000 0,03496944 0,12469723 ! endochondral ossification GO:0001958 12 5 0,000 0,03496944 0,1245042 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03496944 0,12431177 ! parathyroid gland development GO:0060017 8 5 0,000 0,03496944 0,12411993 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03496944 0,12392868 ! anagen GO:0042640 6 5 0,000 0,03496944 0,12373803 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03496944 0,12354795 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03496944 0,12335846 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03496944 0,12316955 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03496944 0,12298122 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03496944 0,12279346 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03496944 0,12260627 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03496944 0,12241966 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03496944 0,12223361 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03496944 0,12204813 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03496944 0,12186321 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03496944 0,12167884 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03496944 0,12149504 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03496944 0,12131179 ! ovulation GO:0030728 6 5 0,000 0,03496944 0,12112909 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03496944 0,12094694 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 9 5 0,000 0,03496944 0,12076534 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03496944 0,12058428 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03496944 0,12040377 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03496944 0,12022379 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03496944 0,12004435 ! polyol catabolic process GO:0046174 7 5 0,000 0,03496944 0,11986545 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03496944 0,11968708 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03496944 0,11950924 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03496944 0,11933192 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03496944 0,11915514 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03496944 0,11897887 ! urea metabolic process GO:0019627 6 5 0,000 0,03496944 0,11880313 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03496944 0,1186279 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03496944 0,11845319 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03496944 0,11827899 ! neutrophil activation GO:0042119 5 5 0,000 0,03496944 0,11810531 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03496944 0,11793214 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03496944 0,11775947 ! response to food GO:0032094 5 5 0,000 0,03496944 0,1175873 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03496944 0,11741564 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03496944 0,11724448 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03496944 0,11707382 ! forebrain neuron development GO:0021884 7 5 0,000 0,03496944 0,11690366 ! melanosome organization GO:0032438 7 5 0,000 0,03496944 0,11673399 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03496944 0,11656481 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03496944 0,11639612 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03496944 0,11622791 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03496944 0,1160602 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03496944 0,11589296 ! nucleoside transport GO:0015858 6 5 0,000 0,03496944 0,11572621 ! nucleoside salvage GO:0043174 7 5 0,000 0,03496944 0,11555994 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03496944 0,11539414 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03496944 0,11522882 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03496944 0,11506397 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03496944 0,11489959 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03496944 0,11473569 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03496944 0,11457225 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03496944 0,11440927 ! depyrimidination GO:0045008 8 5 0,000 0,03496944 0,11424676 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03496944 0,1140847 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03496944 0,11392311 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03496944 0,11376197 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03496944 0,11360129 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03496944 0,11344107 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03496944 0,11328129 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03496944 0,11312196 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03496944 0,11296308 ! monocyte differentiation GO:0030224 8 5 0,000 0,03496944 0,11280465 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03496944 0,11264666 ! centrosome duplication GO:0051298 5 5 0,000 0,03496944 0,11248911 ! response to UV-C GO:0010225 6 5 0,000 0,03496944 0,11233201 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03496944 0,11217534 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03496944 0,1120191 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03496944 0,11186331 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03496944 0,11170794 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03496944 0,111553 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03496944 0,1113985 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03496944 0,11124442 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03496944 0,11109077 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03496944 0,11093754 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03496944 0,11078473 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03496944 0,11063235 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03496944 0,11048038 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03496944 0,11032883 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03496944 0,11017769 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03496944 0,11002697 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03496944 0,10987666 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03496944 0,10972676 ! neural tube patterning GO:0021532 6 5 0,000 0,03496944 0,10957727 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03496944 0,10942819 ! histone demethylation GO:0016577 9 5 0,000 0,03496944 0,10927951 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03496944 0,10913123 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03496944 0,10898336 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03496944 0,10883588 ! enteric nervous system development GO:0048484 8 5 0,000 0,03496944 0,10868881 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03496944 0,10854213 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03496944 0,10839584 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03496944 0,10824995 ! transcription termination GO:0006353 8 5 0,000 0,03496944 0,10810446 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03496944 0,10795935 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03496944 0,10781463 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03496944 0,1076703 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03496944 0,10752636 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03496944 0,1073828 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03496944 0,10723962 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03496944 0,10709683 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03496944 0,10695441 ! apical protein localization GO:0045176 6 5 0,000 0,03496944 0,10681237 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03496944 0,10667071 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03496944 0,10652943 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03496944 0,10638851 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03496944 0,10624797 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03496944 0,10610781 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03496944 0,10596801 ! glial cell migration GO:0008347 10 5 0,000 0,03496944 0,10582857 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03496944 0,10568951 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03496944 0,10555081 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03496944 0,10541247 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03496944 0,1052745 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03496944 0,10513688 ! neural plate development GO:0001840 6 5 0,000 0,03496944 0,10499963 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03496944 0,10486273 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03496944 0,10472619 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03496944 0,10459001 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03496944 0,10445418 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03496944 0,1043187 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03496944 0,10418357 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03496944 0,10404879 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03496944 0,10391436 ! spindle assembly GO:0051225 5 5 0,000 0,03496944 0,10378028 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03496944 0,10364654 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03496944 0,10351315 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03496944 0,1033801 ! organ regeneration GO:0031100 7 5 0,000 0,03496944 0,10324739 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03496944 0,10311502 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03496944 0,10298299 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03496944 0,1028513 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03496944 0,10271994 GO:0055081|anion homeostasis, ! receptor-mediated endocytosis GO:0006898 76 42 1,000 0,03572932 0,10481815 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,03572932 0,10468462 ! excretion GO:0007588 63 42 1,000 0,03572932 0,10455144 ! positive regulation of binding GO:0051099 59 43 1,000 0,03730172 0,10901392 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,03730172 0,10887558 ! activation of caspase activity GO:0006919 65 43 1,000 0,03730172 0,10873759 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 0,03730172 0,10859994 ! vesicle organization GO:0016050 79 43 1,000 0,03730172 0,10846265 ! methylation GO:0032259 64 43 1,000 0,03730172 0,1083257 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,0389003 0,11282558 ! tRNA transcription GO:0009304 11 6 0,000 0,04181637 0,12113055 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04181637 0,12097818 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04181637 0,1208262 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04181637 0,1206746 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04181637 0,12052338 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04181637 0,12037253 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04181637 0,12022207 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04181637 0,12007198 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04181637 0,11992226 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04181637 0,11977292 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04181637 0,11962395 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04181637 0,11947535 ! prostate gland development GO:0030850 9 6 0,000 0,04181637 0,11932711 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04181637 0,11917925 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04181637 0,11903175 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04181637 0,11888462 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04181637 0,11873785 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04181637 0,11859144 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04181637 0,11844539 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04181637 0,1182997 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04181637 0,11815437 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04181637 0,11800939 ! neuron adhesion GO:0007158 9 6 0,000 0,04181637 0,11786477 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04181637 0,11772051 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04181637 0,11757659 ! signal peptide processing GO:0006465 8 6 0,000 0,04181637 0,11743303 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04181637 0,11728982 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04181637 0,11714696 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04181637 0,11700445 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04181637 0,11686228 ! opsonization GO:0008228 8 6 0,000 0,04181637 0,11672045 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04181637 0,11657898 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04181637 0,11643784 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04181637 0,11629704 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04181637 0,11615659 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04181637 0,11601647 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04181637 0,11587669 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04181637 0,11573725 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04181637 0,11559814 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04181637 0,11545937 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04181637 0,11532093 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04181637 0,11518282 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04181637 0,11504504 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04181637 0,11490759 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04181637 0,11477047 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04181637 0,11463368 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04181637 0,11449721 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04181637 0,11436106 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04181637 0,11422524 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04181637 0,11408974 ! thymic T cell selection GO:0045061 12 6 0,000 0,04181637 0,11395457 ! protein lipoylation GO:0009249 10 6 0,000 0,04181637 0,11381971 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04181637 0,11368517 ! drug transport GO:0015893 6 6 0,000 0,04181637 0,11355095 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04181637 0,11341705 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04181637 0,11328346 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04181637 0,11315018 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04181637 0,11301722 ! histidine metabolic process GO:0006547 6 6 0,000 0,04181637 0,11288457 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04181637 0,11275223 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04181637 0,1126202 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,04181637 0,11248848 ! adenohypophysis development GO:0021984 10 6 0,000 0,04181637 0,11235707 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04181637 0,11222597 ! hyperosmotic response GO:0006972 8 6 0,000 0,04181637 0,11209517 ! microtubule nucleation GO:0007020 10 6 0,000 0,04181637 0,11196467 ! ER overload response GO:0006983 7 6 0,000 0,04181637 0,11183448 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04181637 0,11170459 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04181637 0,11157501 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04181637 0,11144572 ! response to dietary excess GO:0002021 7 6 0,000 0,04181637 0,11131673 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04181637 0,11118804 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04181637 0,11105965 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04181637 0,11093155 ! purine salvage GO:0043101 8 6 0,000 0,04181637 0,11080375 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04181637 0,11067624 ! organic alcohol transport GO:0015850 9 6 0,000 0,04181637 0,11054903 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04181637 0,11042211 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04181637 0,11029548 ! carnitine transport GO:0015879 8 6 0,000 0,04181637 0,11016913 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04181637 0,11004308 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04181637 0,10991732 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04181637 0,10979184 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04181637 0,10966665 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04181637 0,10954175 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04181637 0,10941713 ! parturition GO:0007567 12 6 0,000 0,04181637 0,10929279 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04181637 0,10916873 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04181637 0,10904496 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04181637 0,10892147 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04181637 0,10879825 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04181637 0,10867532 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04181637 0,10855266 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04181637 0,10843028 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04181637 0,10830817 ! macrophage differentiation GO:0030225 10 6 0,000 0,04181637 0,10818634 ! astrocyte development GO:0014002 14 6 0,000 0,04181637 0,10806478 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04181637 0,1079435 ! interaction with symbiont GO:0051702 8 6 0,000 0,04181637 0,10782248 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04181637 0,10770174 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04181637 0,10758127 ! eating behavior GO:0042755 6 6 0,000 0,04181637 0,10746107 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04181637 0,10734113 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04181637 0,10722147 ! response to copper ion GO:0046688 9 6 0,000 0,04181637 0,10710207 ! DNA topological change GO:0006265 8 6 0,000 0,04181637 0,10698293 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04181637 0,10686406 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04181637 0,10674545 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04181637 0,10662711 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04181637 0,10650903 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04181637 0,10639121 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04181637 0,10627365 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04181637 0,10615635 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04181637 0,10603931 ! gas homeostasis GO:0033483 11 6 0,000 0,04181637 0,10592253 ! hair follicle maturation GO:0048820 7 6 0,000 0,04181637 0,105806 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04181637 0,10568973 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04181637 0,10557372 ! Schwann cell development GO:0014044 14 6 0,000 0,04181637 0,10545795 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04181637 0,10534245 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04181637 0,10522719 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04181637 0,10511219 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04181637 0,10499744 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04181637 0,10488294 ! histone ubiquitination GO:0016574 7 6 0,000 0,04181637 0,10476869 ! regulation of meiosis GO:0040020 10 6 0,000 0,04181637 0,10465468 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04181637 0,10454093 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04181637 0,10442742 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04181637 0,10431416 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04181637 0,10420114 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04181637 0,10408837 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04181637 0,10397584 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04181637 0,10386356 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04181637 0,10375152 ! receptor internalization GO:0031623 9 6 0,000 0,04181637 0,10363971 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04181637 0,10352815 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04181637 0,10341683 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04181637 0,10330575 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04181637 0,10319491 ! protein deubiquitination GO:0016579 8 6 0,000 0,04181637 0,1030843 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04181637 0,10297393 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04181637 0,1028638 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04181637 0,1027539 ! axonal fasciculation GO:0007413 9 6 0,000 0,04181637 0,10264424 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04181637 0,10253481 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04181637 0,10242562 ! midbrain development GO:0030901 6 6 0,000 0,04181637 0,10231665 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04181637 0,10220792 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04181637 0,10209942 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04181637 0,10199115 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04181637 0,10188311 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04181637 0,1017753 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04181637 0,10166771 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04181637 0,10156035 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04181637 0,10145322 ! adult feeding behavior GO:0008343 6 6 0,000 0,04181637 0,10134632 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04181637 0,10123964 ! blastocyst growth GO:0001832 15 6 0,000 0,04181637 0,10113318 ! pigment granule transport GO:0051904 12 6 0,000 0,04181637 0,10102695 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04181637 0,10092094 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04181637 0,10081515 ! catecholamine transport GO:0051937 7 6 0,000 0,04181637 0,10070959 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04181637 0,10060424 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04181637 0,10049912 ! protein prenylation GO:0018342 10 6 0,000 0,04181637 0,10039421 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04181637 0,10028952 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04181637 0,10018506 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04181637 0,10008081 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04181637 0,09997677 ! regulation of ossification GO:0030278 71 46 1,000 0,04217421 0,10072761 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,04384868 0,10461821 ! glutamine family amino acid metabolic process GO:0009064 59 47 1,000 0,04384868 0,1045098 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,04384868 0,10440161 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,04554757 0,10833445 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 1,000 0,04554757 0,10822253 ! gastrulation GO:0007369 73 48 1,000 0,04554757 0,10811085 ! heart morphogenesis GO:0003007 65 48 1,000 0,04554757 0,10799939 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,04554757 0,10788817 ! germ cell development GO:0007281 68 49 1,000 0,04727047 0,11185399 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,04727047 0,11173903 ! maintenance of location GO:0051235 84 49 1,000 0,04727047 0,11162431 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04861511 0,1146818 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04861511 0,1145643 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04861511 0,11444704 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04861511 0,11433002 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04861511 0,11421323 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04861511 0,11409669 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04861511 0,11398038 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04861511 0,11386431 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04861511 0,11374848 ! reproductive behavior GO:0019098 12 7 0,000 0,04861511 0,11363288 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04861511 0,11351752 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,04861511 0,11340239 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04861511 0,11328749 ! oligopeptide transport GO:0006857 11 7 0,000 0,04861511 0,11317283 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04861511 0,1130584 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04861511 0,1129442 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04861511 0,11283023 ! RNA methylation GO:0001510 11 7 0,000 0,04861511 0,11271649 ! pericardium development GO:0060039 8 7 0,000 0,04861511 0,11260298 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04861511 0,11248969 ! fibril organization GO:0043206 13 7 0,000 0,04861511 0,11237664 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04861511 0,11226381 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,04861511 0,11215121 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04861511 0,11203883 ! lipoprotein transport GO:0042953 9 7 0,000 0,04861511 0,11192668 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04861511 0,11181476 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04861511 0,11170305 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04861511 0,11159157 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04861511 0,11148031 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04861511 0,11136928 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04861511 0,11125846 ! chemosensory behavior GO:0007635 9 7 0,000 0,04861511 0,11114787 ! microtubule bundle formation GO:0001578 8 7 0,000 0,04861511 0,11103749 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04861511 0,11092734 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04861511 0,1108174 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04861511 0,11070768 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04861511 0,11059818 ! reflex GO:0060004 12 7 0,000 0,04861511 0,11048889 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04861511 0,11037982 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04861511 0,11027096 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04861511 0,11016232 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04861511 0,11005389 ! spinal cord patterning GO:0021511 7 7 0,000 0,04861511 0,10994568 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,04861511 0,10983768 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04861511 0,10972989 ! adrenal gland development GO:0030325 17 7 0,000 0,04861511 0,10962231 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04861511 0,10951494 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04861511 0,10940778 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04861511 0,10930084 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04861511 0,1091941 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04861511 0,10908757 ! endosome organization GO:0007032 10 7 0,000 0,04861511 0,10898124 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04861511 0,10887513 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04861511 0,10876922 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04861511 0,10866351 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04861511 0,10855801 ! galactose metabolic process GO:0006012 10 7 0,000 0,04861511 0,10845272 ! vesicle fusion GO:0006906 15 7 0,000 0,04861511 0,10834763 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04861511 0,10824274 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04861511 0,10813806 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04861511 0,10803358 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04861511 0,1079293 ! retinol metabolic process GO:0042572 9 7 0,000 0,04861511 0,10782522 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04861511 0,10772134 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04861511 0,10761767 ! rRNA modification GO:0000154 12 7 0,000 0,04861511 0,10751419 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04861511 0,10741091 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04861511 0,10730783 ! intermediate filament organization GO:0045109 11 7 0,000 0,04861511 0,10720494 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04861511 0,10710226 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04861511 0,10699977 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04861511 0,10689747 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04861511 0,10679537 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04861511 0,10669347 ! response to tropane GO:0014073 13 7 0,000 0,04861511 0,10659176 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04861511 0,10649024 ! melanosome localization GO:0032400 10 7 0,000 0,04861511 0,10638892 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04861511 0,10628779 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04861511 0,10618685 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04861511 0,10608611 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04861511 0,10598555 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04861511 0,10588518 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04861511 0,10578501 ! mast cell activation GO:0045576 9 7 0,000 0,04861511 0,10568502 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04861511 0,10558523 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,04861511 0,10548562 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04861511 0,1053862 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04861511 0,10528696 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04861511 0,10518792 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04861511 0,10508906 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04861511 0,10499038 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04861511 0,10489189 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04861511 0,10479358 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04861511 0,10469546 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04861511 0,10459753 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04861511 0,10449977 ! response to tumor cell GO:0002347 12 7 0,000 0,04861511 0,1044022 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04861511 0,10430481 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04861511 0,1042076 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04861511 0,10411057 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04861511 0,10401373 ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04861511 0,10391706 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,04861511 0,10382057 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04861511 0,10372426 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04861511 0,10362813 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04861511 0,10353218 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04861511 0,10343641 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04861511 0,10334081 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04861511 0,10324539 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04861511 0,10315014 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,04861511 0,10305507 ! lymph node development GO:0048535 9 7 0,000 0,04861511 0,10296018 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04861511 0,10286546 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04861511 0,10277091 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04861511 0,10267654 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04861511 0,10258234 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04861511 0,10248832 ! ATP catabolic process GO:0006200 10 7 0,000 0,04861511 0,10239446 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04861511 0,10230078 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,04861511 0,10220727 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04861511 0,10211393 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04861511 0,10202076 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04861511 0,10192776 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04861511 0,10183493 ! muscle adaptation GO:0043500 12 7 0,000 0,04861511 0,10174227 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04861511 0,10164978 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04861511 0,10155745 ! retina homeostasis GO:0001895 9 7 0,000 0,04861511 0,1014653 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04861511 0,1013733 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04861511 0,10128148 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04861511 0,10118982 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04861511 0,10109833 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,04901695 0,1018419 ! lipid modification GO:0030258 73 50 1,000 0,04901695 0,10174999 ! muscle fiber development GO:0048747 74 51 1,000 0,0507866 0,10532839 ! establishment of organelle localization GO:0051656 85 52 1,000 0,05257902 0,10894751 ! single fertilization GO:0007338 59 53 1,000 0,05439378 0,11260639 ! cell projection assembly GO:0030031 76 53 1,000 0,05439378 0,11250513 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,055366 0,11441311 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,055366 0,11431041 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,055366 0,11420789 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,055366 0,11410555 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,055366 0,11400339 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,055366 0,11390142 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,055366 0,11379964 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,055366 0,11369803 ! phosphate transport GO:0006817 10 8 0,000 0,055366 0,1135966 ! N-glycan processing GO:0006491 12 8 0,000 0,055366 0,11349536 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,055366 0,11339429 ! UTP metabolic process GO:0046051 8 8 0,000 0,055366 0,11329341 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,055366 0,1131927 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,055366 0,11309218 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,055366 0,11299183 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,055366 0,11289166 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,055366 0,11279167 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,055366 0,11269185 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,055366 0,11259221 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,055366 0,11249275 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,055366 0,11239346 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,055366 0,11229435 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,055366 0,11219541 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,055366 0,11209665 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,055366 0,11199806 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,055366 0,11189964 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,055366 0,1118014 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,055366 0,11170333 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,055366 0,11160543 ! astrocyte differentiation GO:0048708 16 8 0,000 0,055366 0,1115077 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,055366 0,11141014 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,055366 0,11131276 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,055366 0,11121554 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,055366 0,11111849 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,055366 0,11102161 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,055366 0,11092491 ! macrophage activation GO:0042116 12 8 0,000 0,055366 0,11082837 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,055366 0,11073199 ! multicellular organism growth GO:0035264 14 8 0,000 0,055366 0,11063579 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,055366 0,11053975 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,055366 0,11044388 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,055366 0,11034817 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,055366 0,11025263 ! ruffle organization GO:0031529 11 8 0,000 0,055366 0,11015726 ! osteoblast development GO:0002076 13 8 0,000 0,055366 0,11006205 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,055366 0,10996701 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,055366 0,10987212 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,055366 0,10977741 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,055366 0,10968285 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,055366 0,10958846 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,055366 0,10949423 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,055366 0,10940016 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,055366 0,10930626 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,055366 0,10921251 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,055366 0,10911893 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,055366 0,10902551 ! oligodendrocyte development GO:0014003 8 8 0,000 0,055366 0,10893224 ! segment specification GO:0007379 10 8 0,000 0,055366 0,10883914 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,055366 0,10874619 ! cellular extravasation GO:0045123 11 8 0,000 0,055366 0,10865341 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,055366 0,10856078 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,055366 0,10846831 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,055366 0,10837599 ! snRNA metabolic process GO:0016073 10 8 0,000 0,055366 0,10828384 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,055366 0,10819184 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,055366 0,10809999 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,055366 0,10800831 ! nucleosome disassembly GO:0006337 12 8 0,000 0,055366 0,10791677 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,055366 0,1078254 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,055366 0,10773417 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,055366 0,1076431 ! icosanoid secretion GO:0032309 12 8 0,000 0,055366 0,10755219 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,055366 0,10746143 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,055366 0,10737082 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,055366 0,10728036 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,055366 0,10719006 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,055366 0,10709991 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,055366 0,10700991 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,055366 0,10692006 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,055366 0,10683036 ! sterol catabolic process GO:0016127 9 8 0,000 0,055366 0,10674081 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,055366 0,10665142 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,055366 0,10656217 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,055366 0,10647307 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,055366 0,10638412 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,055366 0,10629532 ! prophase GO:0051324 11 8 0,000 0,055366 0,10620667 ! S phase GO:0051320 8 8 0,000 0,055366 0,10611816 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,055366 0,1060298 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,055366 0,10594159 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,055366 0,10585353 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,055366 0,10576561 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,055366 0,10567784 ! hormone catabolic process GO:0042447 13 8 0,000 0,055366 0,10559021 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,055366 0,10550273 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,055366 0,10541539 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,055366 0,1053282 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,055366 0,10524115 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,055366 0,10515425 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,055366 0,10506749 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,055366 0,10498087 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,055366 0,10489439 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,055366 0,10480806 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,055366 0,10472187 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,055366 0,10463582 ! lamellipodium assembly GO:0030032 9 8 0,000 0,055366 0,10454991 ! mitochondrion localization GO:0051646 12 8 0,000 0,055366 0,10446414 ! amino acid transport GO:0006865 84 54 1,000 0,0562305 0,10600832 ! gonad development GO:0008406 79 57 1,000 0,06186842 0,11654166 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06206936 0,1168245 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06206936 0,11672897 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06206936 0,11663361 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06206936 0,11653839 ! CTP metabolic process GO:0046036 9 9 0,000 0,06206936 0,11644334 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06206936 0,11634844 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,06206936 0,11625369 ! GTP metabolic process GO:0046039 9 9 0,000 0,06206936 0,1161591 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06206936 0,11606466 ! social behavior GO:0035176 14 9 0,000 0,06206936 0,11597038 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06206936 0,11587624 ! artery development GO:0060840 19 9 0,000 0,06206936 0,11578227 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,06206936 0,11568844 ! response to pain GO:0048265 16 9 0,000 0,06206936 0,11559476 ! protein complex disassembly GO:0043241 17 9 0,000 0,06206936 0,11550124 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06206936 0,11540787 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06206936 0,11531465 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06206936 0,11522158 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06206936 0,11512866 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06206936 0,11503589 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06206936 0,11494326 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06206936 0,11485079 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06206936 0,11475847 ! protein targeting to ER GO:0045047 19 9 0,000 0,06206936 0,11466629 ! endoderm development GO:0007492 12 9 0,000 0,06206936 0,11457426 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06206936 0,11448238 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06206936 0,11439065 ! arginine catabolic process GO:0006527 10 9 0,000 0,06206936 0,11429907 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,06206936 0,11420763 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06206936 0,11411633 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06206936 0,11402519 ! V(D)J recombination GO:0033151 12 9 0,000 0,06206936 0,11393418 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06206936 0,11384333 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06206936 0,11375262 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06206936 0,11366205 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06206936 0,11357163 ! mannose metabolic process GO:0006013 9 9 0,000 0,06206936 0,11348135 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06206936 0,11339121 ! receptor clustering GO:0043113 15 9 0,000 0,06206936 0,11330122 ! epithelial cell development GO:0002064 10 9 0,000 0,06206936 0,11321137 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06206936 0,11312166 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06206936 0,11303209 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06206936 0,11294267 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06206936 0,11285339 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,06206936 0,11276424 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,06206936 0,11267524 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06206936 0,11258638 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06206936 0,11249766 ! DNA ligation GO:0006266 14 9 0,000 0,06206936 0,11240908 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06206936 0,11232064 ! response to amine stimulus GO:0014075 13 9 0,000 0,06206936 0,11223234 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06206936 0,11214417 ! erythrocyte development GO:0048821 11 9 0,000 0,06206936 0,11205615 ! postreplication repair GO:0006301 11 9 0,000 0,06206936 0,11196826 ! mRNA cleavage GO:0006379 13 9 0,000 0,06206936 0,11188051 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06206936 0,1117929 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,06206936 0,11170543 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06206936 0,11161809 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06206936 0,11153089 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06206936 0,11144382 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06206936 0,11135689 ! acid secretion GO:0046717 14 9 0,000 0,06206936 0,1112701 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06206936 0,11118344 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06206936 0,11109691 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06206936 0,11101052 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06206936 0,11092427 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,06206936 0,11083815 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06206936 0,11075216 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06206936 0,11066631 ! detection of calcium ion GO:0005513 13 9 0,000 0,06206936 0,11058058 ! blastocyst formation GO:0001825 12 9 0,000 0,06206936 0,110495 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06206936 0,11040954 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06206936 0,11032421 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06206936 0,11023902 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06206936 0,11015396 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06206936 0,11006903 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,06206936 0,10998423 ! prepulse inhibition GO:0060134 14 9 0,000 0,06206936 0,10989956 ! embryonic placenta development GO:0001892 12 9 0,000 0,06206936 0,10981503 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06206936 0,10973062 ! insulin secretion GO:0030073 17 9 0,000 0,06206936 0,10964634 ! sequestering of metal ion GO:0051238 11 9 0,000 0,06206936 0,10956219 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06206936 0,10947817 ! nucleus localization GO:0051647 15 9 0,000 0,06206936 0,10939428 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06206936 0,10931052 ! viral reproductive process GO:0022415 87 58 1,000 0,06378902 0,11225306 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,06768988 0,11902655 ! fertilization GO:0009566 68 60 1,000 0,06768988 0,11893562 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,06872554 0,12066316 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,06872554 0,12057112 ! neuron fate specification GO:0048665 11 10 0,000 0,06872554 0,12047923 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,06872554 0,12038747 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,06872554 0,12029585 ! thyroid gland development GO:0030878 19 10 0,000 0,06872554 0,12020437 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,06872554 0,12011303 ! synapsis GO:0007129 13 10 0,000 0,06872554 0,12002182 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,06872554 0,11993076 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,06872554 0,11983984 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,06872554 0,11974905 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,06872554 0,1196584 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,06872554 0,11956788 ! androgen metabolic process GO:0008209 13 10 0,000 0,06872554 0,11947751 ! phospholipid efflux GO:0033700 16 10 0,000 0,06872554 0,11938727 ! hippocampus development GO:0021766 19 10 0,000 0,06872554 0,11929716 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,06872554 0,1192072 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,06872554 0,11911736 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,06872554 0,11902767 ! pathogenesis GO:0009405 13 10 0,000 0,06872554 0,11893811 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,06872554 0,11884868 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06872554 0,11875939 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,06872554 0,11867023 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,06872554 0,1185812 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,06872554 0,11849231 ! melanocyte differentiation GO:0030318 15 10 0,000 0,06872554 0,11840355 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,06872554 0,11831493 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,06872554 0,11822643 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06872554 0,11813807 ! response to X-ray GO:0010165 16 10 0,000 0,06872554 0,11804985 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,06872554 0,11796175 ! forebrain cell migration GO:0021885 17 10 0,000 0,06872554 0,11787378 ! lipid digestion GO:0044241 15 10 0,000 0,06872554 0,11778595 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,06872554 0,11769825 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,06872554 0,11761067 ! UV protection GO:0009650 14 10 0,000 0,06872554 0,11752323 ! entry into host cell GO:0030260 20 10 0,000 0,06872554 0,11743592 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,06872554 0,11734873 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,06872554 0,11726168 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,06872554 0,11717475 ! regulation of organ growth GO:0046620 11 10 0,000 0,06872554 0,11708796 ! response to dsRNA GO:0043331 18 10 0,000 0,06872554 0,11700129 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,06872554 0,11691475 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06872554 0,11682834 ! embryonic axis specification GO:0000578 12 10 0,000 0,06872554 0,11674206 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,06872554 0,1166559 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,06872554 0,11656987 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,06872554 0,11648397 ! fucose catabolic process GO:0019317 16 10 0,000 0,06872554 0,11639819 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,06872554 0,11631254 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,06872554 0,11622702 ! protein sumoylation GO:0016925 12 10 0,000 0,06872554 0,11614162 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,06872554 0,11605635 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06872554 0,1159712 ! zymogen activation GO:0031638 14 10 0,000 0,06872554 0,11588618 ! salivary gland development GO:0007431 22 10 0,000 0,06872554 0,11580128 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06872554 0,1157165 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,06872554 0,11563185 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,06872554 0,11554733 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,06872554 0,11546292 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,06872554 0,11537864 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,06872554 0,11529449 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,06872554 0,11521045 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,06872554 0,11512654 ! detection of bacterium GO:0016045 10 10 0,000 0,06872554 0,11504275 ! embryonic gut development GO:0048566 11 10 0,000 0,06872554 0,11495909 ! activation of innate immune response GO:0002218 10 10 0,000 0,06872554 0,11487554 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,06872554 0,11479212 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,06872554 0,11470881 ! developmental induction GO:0031128 13 10 0,000 0,06872554 0,11462563 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,06872554 0,11454257 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,06872554 0,11445963 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,06872554 0,1143768 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,06872554 0,1142941 ! meiosis GO:0007126 96 61 1,000 0,06966939 0,11578006 GO:0051327|M phase of meiotic cell cycle, ! homeostasis of number of cells GO:0048872 84 61 1,000 0,06966939 0,11569647 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,06966939 0,11561299 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cellular hormone metabolic process GO:0034754 87 62 1,000 0,0716678 0,11884351 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,0716678 0,11875789 ! meiotic cell cycle GO:0051321 97 62 1,000 0,0716678 0,11867239 ! organelle localization GO:0051640 96 62 1,000 0,0716678 0,11858702 ! viral reproduction GO:0016032 92 63 1,000 0,07368475 0,12183676 ! rRNA transcription GO:0009303 17 11 0,000 0,07533486 0,1244757 ! respiratory burst GO:0045730 14 11 0,000 0,07533486 0,12438634 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07533486 0,12429712 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07533486 0,12420801 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07533486 0,12411904 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07533486 0,12403019 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07533486 0,12394147 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07533486 0,12385288 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07533486 0,12376441 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,07533486 0,12367607 ! mating GO:0007618 14 11 0,000 0,07533486 0,12358786 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,07533486 0,12349977 ! T cell proliferation GO:0042098 20 11 0,000 0,07533486 0,12341181 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,07533486 0,12332397 ! bone resorption GO:0045453 16 11 0,000 0,07533486 0,12323626 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07533486 0,12314867 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07533486 0,12306121 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07533486 0,12297387 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07533486 0,12288665 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07533486 0,12279956 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07533486 0,12271259 ! syncytium formation GO:0006949 15 11 0,000 0,07533486 0,12262575 ! plasma membrane organization GO:0007009 18 11 0,000 0,07533486 0,12253902 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07533486 0,12245242 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07533486 0,12236595 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07533486 0,12227959 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,07533486 0,12219336 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07533486 0,12210724 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07533486 0,12202125 ! adult heart development GO:0007512 11 11 0,000 0,07533486 0,12193538 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,07533486 0,12184963 ! temperature homeostasis GO:0001659 16 11 0,000 0,07533486 0,121764 ! L-glutamate transport GO:0015813 16 11 0,000 0,07533486 0,1216785 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07533486 0,12159311 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07533486 0,12150784 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07533486 0,12142269 ! stem cell development GO:0048864 29 11 0,000 0,07533486 0,12133766 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07533486 0,12125275 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07533486 0,12116796 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07533486 0,12108328 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07533486 0,12099873 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07533486 0,12091429 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07533486 0,12082997 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07533486 0,12074577 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07533486 0,12066168 ! ribosome assembly GO:0042255 13 11 0,000 0,07533486 0,12057772 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07533486 0,12049387 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07533486 0,12041013 ! chromatin silencing GO:0006342 19 11 0,000 0,07533486 0,12032651 ! nucleosome positioning GO:0016584 13 11 0,000 0,07533486 0,12024301 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07533486 0,12015962 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07533486 0,12007635 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07533486 0,1199932 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07533486 0,11991016 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07533486 0,11982723 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07533486 0,11974442 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07533486 0,11966173 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07533486 0,11957914 ! male genitalia development GO:0030539 13 11 0,000 0,07533486 0,11949667 ! cholesterol efflux GO:0033344 19 11 0,000 0,07533486 0,11941432 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07533486 0,11933208 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07533486 0,11924995 ! germ cell migration GO:0008354 18 11 0,000 0,07533486 0,11916794 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07533486 0,11908603 ! defense response to fungus GO:0050832 12 11 0,000 0,07533486 0,11900424 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07533486 0,11892257 ! lysogeny GO:0030069 18 11 0,000 0,07533486 0,118841 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07533486 0,11875955 ! acrosome reaction GO:0007340 13 11 0,000 0,07533486 0,1186782 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07533486 0,11859697 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,07571988 0,11912155 ! adaptive immune response GO:0002250 94 64 1,000 0,07571988 0,11904013 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 1,000 0,07777282 0,12218408 ! regulation of caspase activity GO:0043281 97 65 1,000 0,07777282 0,12210068 ! B cell activation GO:0042113 104 65 1,000 0,07777282 0,12201739 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,07777282 0,12193421 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,07777282 0,12185115 ! protein oligomerization GO:0051259 100 65 1,000 0,07777282 0,1217682 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,07984324 0,1249248 ! axon guidance GO:0007411 99 66 1,000 0,07984324 0,12483987 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,07984324 0,12475506 ! lactation GO:0007595 20 12 0,000 0,08189765 0,1278782 ! reproductive cellular process GO:0048610 14 12 0,000 0,08189765 0,12779145 ! tRNA modification GO:0006400 14 12 0,000 0,08189765 0,12770481 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08189765 0,12761829 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08189765 0,12753188 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08189765 0,1274456 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08189765 0,12735943 ! non-recombinational repair GO:0000726 19 12 0,000 0,08189765 0,12727337 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08189765 0,12718744 ! peroxisomal transport GO:0043574 21 12 0,000 0,08189765 0,12710161 ! cartilage condensation GO:0001502 18 12 0,000 0,08189765 0,12701591 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08189765 0,12693032 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08189765 0,12684484 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08189765 0,12675948 ! heart looping GO:0001947 15 12 0,000 0,08189765 0,12667424 ! palate development GO:0060021 15 12 0,000 0,08189765 0,12658911 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,08189765 0,12650409 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08189765 0,12641919 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08189765 0,1263344 ! arginine metabolic process GO:0006525 13 12 0,000 0,08189765 0,12624973 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,08189765 0,12616517 ! methionine metabolic process GO:0006555 13 12 0,000 0,08189765 0,12608072 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08189765 0,12599638 ! Golgi organization GO:0007030 18 12 0,000 0,08189765 0,12591216 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08189765 0,12582805 ! monoamine transport GO:0015844 13 12 0,000 0,08189765 0,12574405 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08189765 0,12566017 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08189765 0,12557639 ! L-amino acid transport GO:0015807 20 12 0,000 0,08189765 0,12549273 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08189765 0,12540918 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08189765 0,12532574 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08189765 0,12524241 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08189765 0,1251592 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08189765 0,12507609 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08189765 0,12499309 ! cerebellum development GO:0021549 13 12 0,000 0,08189765 0,12491021 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08189765 0,12482743 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08189765 0,12474476 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08189765 0,12466221 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08189765 0,12457976 ! regulation of epidermis development GO:0045682 17 12 0,000 0,08189765 0,12449742 ! intestinal absorption GO:0050892 19 12 0,000 0,08189765 0,12441519 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08189765 0,12433306 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08189765 0,12425105 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08189765 0,12416914 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08189765 0,12408735 ! microspike assembly GO:0030035 23 12 0,000 0,08189765 0,12400566 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08189765 0,12392407 ! response to cold GO:0009409 14 12 0,000 0,08189765 0,1238426 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 1,000 0,08193079 0,12381131 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,08193079 0,12373001 ! acute inflammatory response GO:0002526 92 68 1,000 0,08403511 0,12682465 ! cytosolic calcium ion homeostasis GO:0051480 107 68 1,000 0,08403511 0,12674148 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,08403511 0,12665843 ! rhythmic process GO:0048511 105 68 1,000 0,08403511 0,12657548 ! response to drug GO:0042493 108 69 1,000 0,08615589 0,12968491 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,08615589 0,12960009 ! response to metal ion GO:0010038 103 70 1,000 0,08829277 0,1327277 ! humoral immune response GO:0006959 86 70 1,000 0,08829277 0,132641 ! amine transport GO:0015837 101 70 1,000 0,08829277 0,13255442 ! regulation of catabolic process GO:0009894 106 70 1,000 0,08829277 0,13246796 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,08841423 0,13256371 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,08841423 0,13247735 ! cGMP metabolic process GO:0046068 16 13 0,000 0,08841423 0,1323911 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,08841423 0,13230496 ! water transport GO:0006833 17 13 0,000 0,08841423 0,13221894 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,08841423 0,13213303 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,08841423 0,13204723 ! lipid localization GO:0010876 24 13 0,000 0,08841423 0,13196154 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,08841423 0,13187596 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,08841423 0,13179049 ! organelle fusion GO:0048284 28 13 0,000 0,08841423 0,13170514 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,08841423 0,13161989 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,08841423 0,13153475 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,08841423 0,13144973 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,08841423 0,13136481 ! response to hexose stimulus GO:0009746 19 13 0,000 0,08841423 0,13128001 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,08841423 0,13119531 ! glutamate metabolic process GO:0006536 18 13 0,000 0,08841423 0,13111072 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,08841423 0,13102624 ! cytokine metabolic process GO:0042107 17 13 0,000 0,08841423 0,13094187 ! NAD metabolic process GO:0019674 21 13 0,000 0,08841423 0,13085761 ! exocrine system development GO:0035272 27 13 0,000 0,08841423 0,13077346 ! bone mineralization GO:0030282 15 13 0,000 0,08841423 0,13068942 ! regulation of exocytosis GO:0017157 17 13 0,000 0,08841423 0,13060548 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,08841423 0,13052165 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,08841423 0,13043793 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,08841423 0,13035431 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,08841423 0,13027081 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,08841423 0,13018741 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,08841423 0,13010411 ! genitalia development GO:0048806 15 13 0,000 0,08841423 0,13002093 ! regulation of cellular pH GO:0030641 20 13 0,000 0,08841423 0,12993785 ! tissue regeneration GO:0042246 21 13 0,000 0,08841423 0,12985487 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,08841423 0,129772 ! cofactor transport GO:0051181 19 13 0,000 0,08841423 0,12968924 ! NADP metabolic process GO:0006739 18 13 0,000 0,08841423 0,12960658 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,08841423 0,12952403 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,08841423 0,12944159 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08841423 0,12935924 ! gas transport GO:0015669 18 13 0,000 0,08841423 0,12927701 ! heme biosynthetic process GO:0006783 20 13 0,000 0,08841423 0,12919487 ! regulation of axon extension GO:0030516 23 13 0,000 0,08841423 0,12911285 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,08841423 0,12903092 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,08841423 0,1289491 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,08841423 0,12886738 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,08841423 0,12878577 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,08841423 0,12870426 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,09044544 0,1315778 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,09044544 0,13149463 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,09261355 0,1345617 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,09261355 0,13447675 ! regulation of blood pressure GO:0008217 107 73 1,000 0,0947968 0,13756003 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,0947968 0,13747329 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,0947968 0,13738667 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,09488493 0,13742779 ! superoxide anion generation GO:0042554 18 14 0,000 0,09488493 0,13734131 ! neuron maturation GO:0042551 21 14 0,000 0,09488493 0,13725493 ! regulation of S phase GO:0033261 18 14 0,000 0,09488493 0,13716866 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09488493 0,1370825 ! myotube differentiation GO:0014902 21 14 0,000 0,09488493 0,13699645 ! inositol metabolic process GO:0006020 20 14 0,000 0,09488493 0,1369105 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09488493 0,13682466 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09488493 0,13673893 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09488493 0,13665331 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09488493 0,1365678 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09488493 0,13648239 ! response to cAMP GO:0051591 19 14 0,000 0,09488493 0,13639709 ! limbic system development GO:0021761 25 14 0,000 0,09488493 0,13631189 ! startle response GO:0001964 21 14 0,000 0,09488493 0,1362268 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09488493 0,13614182 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09488493 0,13605694 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09488493 0,13597217 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09488493 0,13588751 ! glycine metabolic process GO:0006544 22 14 0,000 0,09488493 0,13580295 ! pituitary gland development GO:0021983 23 14 0,000 0,09488493 0,13571849 ! cellular response to starvation GO:0009267 21 14 0,000 0,09488493 0,13563414 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,09488493 0,1355499 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,09488493 0,13546576 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09488493 0,13538172 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09488493 0,13529779 ! embryo implantation GO:0007566 27 14 0,000 0,09488493 0,13521396 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,09488493 0,13513024 ! intermediate filament-based process GO:0045103 24 14 0,000 0,09488493 0,13504662 ! axon cargo transport GO:0008088 27 14 0,000 0,09488493 0,1349631 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09488493 0,13487969 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09488493 0,13479638 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09488493 0,13471317 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09488493 0,13463007 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09488493 0,13454706 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09488493 0,13446416 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09488493 0,13438137 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09488493 0,13429867 GO:0046466|membrane lipid catabolic process, ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09488493 0,13421608 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,09488493 0,13413358 ! muscle maintenance GO:0046716 19 14 0,000 0,09488493 0,13405119 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09488493 0,1339689 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09488493 0,13388671 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,09488493 0,13380462 ! cell killing GO:0001906 20 14 0,000 0,09488493 0,13372263 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,09488493 0,13364075 ! cilium assembly GO:0042384 20 14 0,000 0,09488493 0,13355896 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,09699486 0,13644537 ! response to inorganic substance GO:0010035 115 75 1,000 0,09920741 0,13947252 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,10131007 0,14234157 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10131007 0,14225467 ! skin development GO:0043588 25 15 0,000 0,10131007 0,14216788 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,10131007 0,14208119 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,10131007 0,14199461 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,10131007 0,14190813 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,10131007 0,14182176 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10131007 0,14173549 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10131007 0,14164933 ! adult walking behavior GO:0007628 25 15 0,000 0,10131007 0,14156327 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10131007 0,14147732 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10131007 0,14139147 ! myoblast differentiation GO:0045445 27 15 0,000 0,10131007 0,14130573 ! centrosome cycle GO:0007098 16 15 0,000 0,10131007 0,14122009 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,10131007 0,14113455 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10131007 0,14104912 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,10131007 0,14096379 ! cerebral cortex development GO:0021987 29 15 0,000 0,10131007 0,14087857 ! response to osmotic stress GO:0006970 22 15 0,000 0,10131007 0,14079344 ! vesicle coating GO:0006901 25 15 0,000 0,10131007 0,14070842 ! DNA integration GO:0015074 22 15 0,000 0,10131007 0,14062351 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,10131007 0,14053869 ! regulation of vasodilation GO:0042312 24 15 0,000 0,10131007 0,14045398 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10131007 0,14036937 ! neuron recognition GO:0008038 22 15 0,000 0,10131007 0,14028486 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10131007 0,14020045 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,10131007 0,14011615 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10131007 0,14003194 ! biomineral formation GO:0031214 18 15 0,000 0,10131007 0,13994784 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10131007 0,13986384 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,10131007 0,13977993 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10131007 0,13969613 ! dopamine metabolic process GO:0042417 30 15 0,000 0,10131007 0,13961243 ! organic cation transport GO:0015695 19 15 0,000 0,10131007 0,13952883 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10131007 0,13944533 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,10131007 0,13936193 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,10131007 0,13927863 ! peptide hormone processing GO:0016486 19 15 0,000 0,10131007 0,13919543 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,10131007 0,13911233 ! sex differentiation GO:0007548 105 77 1,000 0,10367476 0,14227443 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,10367476 0,14218959 ! protein secretion GO:0009306 27 16 0,000 0,10768996 0,1476084 ! bone remodeling GO:0046849 24 16 0,000 0,10768996 0,14752049 ! endothelial cell migration GO:0043542 22 16 0,000 0,10768996 0,14743268 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,10768996 0,14734497 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10768996 0,14725737 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,10768996 0,14716987 ! glial cell development GO:0021782 24 16 0,000 0,10768996 0,14708248 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,10768996 0,14699519 GO:0042744|hydrogen peroxide catabolic process, ! protein polyubiquitination GO:0000209 26 16 0,000 0,10768996 0,14690801 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,10768996 0,14682092 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,10768996 0,14673394 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,10768996 0,14664707 ! fructose metabolic process GO:0006000 20 16 0,000 0,10768996 0,1465603 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,10768996 0,14647362 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,10768996 0,14638706 ! protein export from nucleus GO:0006611 24 16 0,000 0,10768996 0,14630059 ! negative regulation of immune response GO:0050777 28 16 0,000 0,10768996 0,14621423 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,10768996 0,14612796 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,10768996 0,1460418 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,10768996 0,14595574 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,10768996 0,14586979 ! diencephalon development GO:0021536 25 16 0,000 0,10768996 0,14578393 ! neural crest cell migration GO:0001755 24 16 0,000 0,10768996 0,14569818 ! G1 phase GO:0051318 27 16 0,000 0,10768996 0,14561252 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,10768996 0,14552697 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,10768996 0,14544151 ! steroid catabolic process GO:0006706 22 16 0,000 0,10768996 0,14535616 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,10768996 0,14527091 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,10768996 0,14518576 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,10768996 0,1451007 ! sperm-egg recognition GO:0035036 16 16 0,000 0,10768996 0,14501575 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,10768996 0,14493089 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,10768996 0,14484614 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,10768996 0,14476148 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,10819638 0,14535729 ! protein localization in nucleus GO:0034504 133 80 1,000 0,1104768 0,14833429 ! forebrain development GO:0030900 131 80 1,000 0,1104768 0,14824775 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,1127699 0,1512366 ! response to protein stimulus GO:0051789 111 81 1,000 0,1127699 0,15114846 ! vitamin metabolic process GO:0006766 103 81 1,000 0,1127699 0,15106043 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,1127699 0,15097251 GO:0002696|positive regulation of leukocyte activation, ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,11402492 0,15256388 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,11402492 0,15247518 ! negative regulation of defense response GO:0031348 19 17 0,000 0,11402492 0,15238658 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,11402492 0,15229809 ! glycerol metabolic process GO:0006071 20 17 0,000 0,11402492 0,1522097 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,11402492 0,15212141 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,11402492 0,15203322 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,11402492 0,15194514 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,11402492 0,15185716 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,11402492 0,15176928 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,11402492 0,1516815 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,11402492 0,15159382 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,11402492 0,15150625 ! keratinization GO:0031424 17 17 0,000 0,11402492 0,15141877 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,11402492 0,1513314 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,11402492 0,15124412 ! retinoid metabolic process GO:0001523 22 17 0,000 0,11402492 0,15115695 GO:0016101|diterpenoid metabolic process, ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,11402492 0,15106988 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,11402492 0,15098291 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,11402492 0,15089604 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,11402492 0,15080926 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,11402492 0,15072259 ! membrane budding GO:0006900 29 17 0,000 0,11402492 0,15063602 ! heme metabolic process GO:0042168 27 17 0,000 0,11402492 0,15054955 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,11402492 0,15046317 ! stem cell differentiation GO:0048863 36 17 0,000 0,11402492 0,1503769 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,11402492 0,15029072 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,11402492 0,15020465 ! sensory perception of pain GO:0019233 23 17 0,000 0,11402492 0,15011867 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,11402492 0,15003279 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,11402492 0,149947 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,11402492 0,14986132 ! synaptogenesis GO:0007416 24 17 0,000 0,11402492 0,14977573 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,11402492 0,14969025 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,11402492 0,14960486 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,11402492 0,14951956 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,11402492 0,14943437 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,11402492 0,14934927 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,11402492 0,14926426 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,11739296 0,15358578 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,11972235 0,15654429 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,12031526 0,15723018 ! positive regulation of translation GO:0045727 28 18 0,000 0,12031526 0,15714089 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,12031526 0,15705171 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,12031526 0,15696263 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,12031526 0,15687364 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,12031526 0,15678476 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,12031526 0,15669598 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,12031526 0,15660731 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,12031526 0,15651873 ! axis specification GO:0009798 26 18 0,000 0,12031526 0,15643025 ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,12031526 0,15634187 ! pancreas development GO:0031016 26 18 0,000 0,12031526 0,15625359 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,12031526 0,15616541 ! pigmentation during development GO:0048066 31 18 0,000 0,12031526 0,15607733 ! central nervous system neuron development GO:0021954 30 18 0,000 0,12031526 0,15598935 ! fucose metabolic process GO:0006004 26 18 0,000 0,12031526 0,15590147 ! response to fungus GO:0009620 19 18 0,000 0,12031526 0,15581369 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,12031526 0,155726 ! heart process GO:0003015 27 18 0,000 0,12031526 0,15563842 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,12031526 0,15555093 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,12031526 0,15546354 ! visual learning GO:0008542 35 18 0,000 0,12031526 0,15537625 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,12031526 0,15528906 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,12031526 0,15520197 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,12031526 0,15511497 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,12031526 0,15502807 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,12031526 0,15494127 ! vitamin transport GO:0051180 24 18 0,000 0,12031526 0,15485457 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,12031526 0,15476796 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,12031526 0,15468145 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,12031526 0,15459503 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,12031526 0,15450872 ! cell-cell recognition GO:0009988 20 18 0,000 0,12031526 0,15442249 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,12031526 0,15433637 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,12031526 0,15425034 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,12031526 0,15416441 ! rRNA metabolic process GO:0016072 107 85 1,000 0,12206328 0,15631711 GO:0006364|rRNA processing, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,12441546 0,15924071 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,12656131 0,16189711 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,12656131 0,16180712 ! positive regulation of ossification GO:0045778 30 19 0,000 0,12656131 0,16171723 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,12656131 0,16162743 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,12656131 0,16153774 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,12656131 0,16144815 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,12656131 0,16135865 ! sensory perception of taste GO:0050909 23 19 0,000 0,12656131 0,16126926 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,12656131 0,16117996 ! peroxisome organization GO:0007031 29 19 0,000 0,12656131 0,16109076 ! digestive system process GO:0022600 30 19 0,000 0,12656131 0,16100166 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,12656131 0,16091266 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,12656131 0,16082376 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,12656131 0,16073496 ! response to starvation GO:0042594 30 19 0,000 0,12656131 0,16064625 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,12656131 0,16055764 ! cytolysis GO:0019835 20 19 0,000 0,12656131 0,16046913 ! vasodilation GO:0042311 33 19 0,000 0,12656131 0,16038072 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,12656131 0,16029241 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,12656131 0,16020419 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,12656131 0,16011607 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,12656131 0,16002804 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,12656131 0,15994012 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,12656131 0,15985228 ! sarcomere organization GO:0045214 23 19 0,000 0,12656131 0,15976455 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,12656131 0,15967691 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,12656131 0,15958937 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,12656131 0,15950192 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,12656131 0,15941457 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,12656131 0,15932732 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,12656131 0,15924016 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,12656131 0,15915309 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,12656131 0,15906613 ! protein stabilization GO:0050821 26 19 0,000 0,12656131 0,15897925 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,1291525 0,16214561 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,13153682 0,16504893 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,13276336 0,16649712 ! iron ion transport GO:0006826 37 20 0,000 0,13276336 0,16640639 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,13276336 0,16631575 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,13276336 0,16622522 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,13276336 0,16613478 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,13276336 0,16604444 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,13276336 0,1659542 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,13276336 0,16586405 ! spinal cord development GO:0021510 31 20 0,000 0,13276336 0,16577401 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,13276336 0,16568406 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,13276336 0,16559421 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,13276336 0,16550446 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,13276336 0,1654148 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,13276336 0,16532524 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,13276336 0,16523578 ! pallium development GO:0021543 38 20 0,000 0,13276336 0,16514642 ! DNA modification GO:0006304 28 20 0,000 0,13276336 0,16505715 ! collagen fibril organization GO:0030199 45 20 0,000 0,13276336 0,16496798 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,13276336 0,1648789 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,13276336 0,16478992 ! collagen catabolic process GO:0030574 25 20 0,000 0,13276336 0,16470104 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,13276336 0,16461225 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,13276336 0,16452356 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,13276336 0,16443496 ! alditol metabolic process GO:0019400 24 20 0,000 0,13276336 0,16434646 ! actin filament-based movement GO:0030048 34 20 0,000 0,13276336 0,16425806 ! leukocyte differentiation GO:0002521 143 90 1,000 0,13393133 0,165614 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,13874983 0,17148018 ! sulfur metabolic process GO:0006790 118 92 1,000 0,13874983 0,17138808 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,13892172 0,1715083 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,13892172 0,17141629 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,13892172 0,17132438 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,13892172 0,17123256 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,13892172 0,17114085 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,13892172 0,17104923 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,13892172 0,17095771 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,13892172 0,17086629 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,13892172 0,17077497 ! vesicle docking GO:0048278 27 21 0,000 0,13892172 0,17068374 ! phototransduction GO:0007602 25 21 0,000 0,13892172 0,17059261 ! dendrite development GO:0016358 35 21 0,000 0,13892172 0,17050158 ! visual behavior GO:0007632 39 21 0,000 0,13892172 0,17041065 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,13892172 0,17031981 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,13892172 0,17022907 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,13892172 0,17013842 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,13892172 0,17004788 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,13892172 0,16995743 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,13892172 0,16986707 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,13892172 0,16977681 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,13892172 0,16968665 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,13892172 0,16959658 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,13892172 0,16950661 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,13892172 0,16941673 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,13892172 0,16932695 ! fatty acid transport GO:0015908 30 21 0,000 0,13892172 0,16923727 ! immunoglobulin production GO:0002377 33 21 0,000 0,13892172 0,16914768 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,13892172 0,16905818 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,13892172 0,16896878 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,13892172 0,16887947 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,13892172 0,16879026 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,13892172 0,16870114 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,13892172 0,16861212 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,13892172 0,16852319 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,13892172 0,16843435 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,13892172 0,16834561 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,13892172 0,16825696 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,13892172 0,1681684 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,14117332 0,17080412 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,1450367 0,17538613 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,1450367 0,17529397 ! viral genome replication GO:0019079 29 22 0,000 0,1450367 0,1752019 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,1450367 0,17510993 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,1450367 0,17501806 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,1450367 0,17492628 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,1450367 0,1748346 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,1450367 0,17474302 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,1450367 0,17465153 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,1450367 0,17456014 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,1450367 0,17446884 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,1450367 0,17437764 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,1450367 0,17428653 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,1450367 0,17419552 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,1450367 0,1741046 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,1450367 0,17401378 ! blastocyst development GO:0001824 37 22 0,000 0,1450367 0,17392306 ! neural tube closure GO:0001843 33 22 0,000 0,1450367 0,17383242 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! carboxylic acid transport GO:0046942 147 95 1,000 0,14604751 0,17495274 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 1,000 0,14849772 0,17779529 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,14849772 0,17770278 ! protein amino acid glycosylation GO:0006486 134 97 1,000 0,15095634 0,18055101 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! neuron fate commitment GO:0048663 32 23 0,000 0,15110861 0,18063919 ! embryonic pattern specification GO:0009880 31 23 0,000 0,15110861 0,18054535 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,15110861 0,18045161 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,15110861 0,18035797 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,15110861 0,18026442 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,15110861 0,18017097 ! vesicle targeting GO:0006903 32 23 0,000 0,15110861 0,18007762 ! osteoblast differentiation GO:0001649 40 23 0,000 0,15110861 0,17998436 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,15110861 0,1798912 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,15110861 0,17979814 ! glycolipid metabolic process GO:0006664 36 23 0,000 0,15110861 0,17970517 ! cell fate determination GO:0001709 45 23 0,000 0,15110861 0,1796123 ! pentose metabolic process GO:0019321 31 23 0,000 0,15110861 0,17951952 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,15110861 0,17942685 ! spermatid development GO:0007286 33 23 0,000 0,15110861 0,17933426 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,15110861 0,17924177 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,15110861 0,17914938 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,15110861 0,17905708 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,15110861 0,17896488 ! telomere organization GO:0032200 32 23 0,000 0,15110861 0,17887277 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,15110861 0,17878076 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,15110861 0,17868884 ! regulation of amine transport GO:0051952 38 23 0,000 0,15110861 0,17859702 ! liver development GO:0001889 40 23 0,000 0,15110861 0,17850529 ! extracellular structure organization GO:0043062 156 99 1,000 0,15589789 0,18406835 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,15713774 0,18543704 ! initiation of viral infection GO:0019059 42 24 0,000 0,15713774 0,18534194 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,15713774 0,18524695 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,15713774 0,18515205 ! superoxide metabolic process GO:0006801 32 24 0,000 0,15713774 0,18505724 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,15713774 0,18496253 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,15713774 0,18486792 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,15713774 0,18477341 ! sperm motility GO:0030317 27 24 0,000 0,15713774 0,18467899 ! vacuole organization GO:0007033 39 24 0,000 0,15713774 0,18458467 ! receptor metabolic process GO:0043112 37 24 0,000 0,15713774 0,18449045 ! primary neural tube formation GO:0014020 35 24 0,000 0,15713774 0,18439632 ! negative regulation of cell development GO:0010721 56 24 0,000 0,15713774 0,18430229 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,15713774 0,18420835 ! base-excision repair GO:0006284 31 24 0,000 0,15713774 0,18411451 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,15713774 0,18402077 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,15713774 0,18392712 ! glutathione metabolic process GO:0006749 29 24 0,000 0,15713774 0,18383357 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,15713774 0,18374011 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,15713774 0,18364674 ! regulation of translation GO:0006417 151 100 1,000 0,15838034 0,18500497 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,15838034 0,18491106 ! protein localization in organelle GO:0033365 161 100 1,000 0,15838034 0,18481724 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,16312438 0,19025664 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,16312438 0,19016021 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,16312438 0,19006387 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,16312438 0,18996764 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,16312438 0,1898715 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,16312438 0,18977546 ! iron ion homeostasis GO:0055072 39 25 0,000 0,16312438 0,18967952 ! phospholipid transport GO:0015914 35 25 0,000 0,16312438 0,18958367 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,16312438 0,18948792 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,16312438 0,18939227 ! detection of light stimulus GO:0009583 30 25 0,000 0,16312438 0,18929671 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,16906885 0,196096 ! translational initiation GO:0006413 43 26 0,000 0,16906885 0,19599716 ! circadian rhythm GO:0007623 42 26 0,000 0,16906885 0,19589842 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,16906885 0,19579978 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,16906885 0,19570124 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,16906885 0,1956028 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,16906885 0,19550446 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,16906885 0,19540621 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,16906885 0,19530807 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,16906885 0,19521002 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,17497143 0,20192388 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,17497143 0,20182262 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,17497143 0,20172145 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,17497143 0,20162039 ! membrane docking GO:0022406 39 27 0,000 0,17497143 0,20151943 ! catechol metabolic process GO:0009712 43 27 0,000 0,17497143 0,20141857 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,17497143 0,20131781 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,17497143 0,20121715 ! myofibril assembly GO:0030239 36 27 0,000 0,17497143 0,20111659 GO:0055002|striated muscle cell development, ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,17497143 0,20101613 ! natural killer cell activation GO:0030101 35 27 0,000 0,17497143 0,20091578 ! lipid oxidation GO:0034440 38 27 0,000 0,17497143 0,20081552 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,17497143 0,20071536 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,17497143 0,2006153 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,17497143 0,20051535 ! gene silencing GO:0016458 41 27 0,000 0,17497143 0,20041549 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,18083242 0,20702567 ! phenol metabolic process GO:0018958 44 28 0,000 0,18083242 0,20692267 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,18083242 0,20681978 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,18083242 0,20671698 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,18083242 0,20661429 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,18083242 0,2065117 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,18083242 0,20640922 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,18083242 0,20630683 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,18083242 0,20620455 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,18083242 0,20610236 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,18083242 0,20600028 GO:0002764|immune response-regulating signal transduction, ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,18083242 0,2058983 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,18083242 0,20579642 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,18083242 0,20569464 ! BMP signaling pathway GO:0030509 40 28 0,000 0,18083242 0,20559297 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,18083242 0,20549139 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,18083242 0,20538991 ! neural tube formation GO:0001841 41 28 0,000 0,18083242 0,20528853 ! placenta development GO:0001890 37 28 0,000 0,18083242 0,20518726 ! regulation of innate immune response GO:0045088 38 29 0,000 0,18665211 0,21168631 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,18665211 0,21158198 ! protein targeting to membrane GO:0006612 53 29 0,000 0,18665211 0,21147776 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,18665211 0,21137363 ! mismatch repair GO:0006298 34 29 0,000 0,18665211 0,21126961 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,18665211 0,21116569 ! muscle cell development GO:0055001 38 29 0,000 0,18665211 0,21106187 ! telencephalon development GO:0021537 52 29 0,000 0,18665211 0,21095816 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,18665211 0,21085454 ! eye morphogenesis GO:0048592 51 29 0,000 0,18665211 0,21075103 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,18665211 0,21064762 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,19243078 0,21706267 ! collagen metabolic process GO:0032963 40 30 0,000 0,19243078 0,21695627 ! organic anion transport GO:0015711 51 30 0,000 0,19243078 0,21684997 ! cholesterol transport GO:0030301 46 30 0,000 0,19243078 0,21674378 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,19243078 0,21663768 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,19243078 0,2165317 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,19243078 0,21642581 ! ceramide metabolic process GO:0006672 43 30 0,000 0,19243078 0,21632003 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,19243078 0,21621436 ! adult locomotory behavior GO:0008344 47 30 0,000 0,19243078 0,21610878 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,19243078 0,21600331 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,19243078 0,21589795 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,19243078 0,21579268 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,19243078 0,21568752 ! glial cell differentiation GO:0010001 55 31 0,000 0,19816872 0,22201074 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,19816872 0,22190266 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,19816872 0,22179468 ! odontogenesis GO:0042476 50 31 0,000 0,19816872 0,2216868 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,19816872 0,22157903 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,19816872 0,22147136 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,19816872 0,2213638 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,19816872 0,22125634 ! RNA modification GO:0009451 40 31 0,000 0,19816872 0,22114898 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,20386622 0,22739685 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,20386622 0,22728663 ! cytokine production GO:0001816 44 32 0,000 0,20386622 0,22717651 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,20386622 0,22706649 ! vesicle localization GO:0051648 47 32 0,000 0,20386622 0,22695659 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,20952356 0,23314184 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,20952356 0,23302911 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,20952356 0,23291648 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,20952356 0,23280396 ! actomyosin structure organization GO:0031032 43 33 0,000 0,20952356 0,23269155 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,20952356 0,23257924 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,20952356 0,23246705 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,20952356 0,23235496 ! lipid homeostasis GO:0055088 55 33 0,000 0,20952356 0,23224298 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,20952356 0,23213111 ! regulation of proteolysis GO:0030162 50 33 0,000 0,20952356 0,23201935 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,20952356 0,2319077 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,20952356 0,23179615 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,20952356 0,23168471 ! mRNA catabolic process GO:0006402 48 34 0,000 0,21514102 0,237782 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,21514102 0,2376678 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,21514102 0,2375537 ! feeding behavior GO:0007631 45 34 0,000 0,21514102 0,23743971 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,21514102 0,23732583 ! neuron migration GO:0001764 46 34 0,000 0,21514102 0,23721206 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,21514102 0,2370984 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,21514102 0,23698484 ! polyol metabolic process GO:0019751 44 34 0,000 0,21514102 0,2368714 ! aerobic respiration GO:0009060 47 34 0,000 0,21514102 0,23675806 ! embryonic organ development GO:0048568 45 34 0,000 0,21514102 0,23664484 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,21514102 0,23653172 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,22071888 0,24254822 ! Notch signaling pathway GO:0007219 56 35 0,000 0,22071888 0,24243239 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,22071888 0,24231667 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,22071888 0,24220106 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,22071888 0,24208557 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,22071888 0,24197018 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,22071888 0,2418549 ! glycogen metabolic process GO:0005977 48 35 0,000 0,22071888 0,24173973 ! protein homooligomerization GO:0051260 52 35 0,000 0,22071888 0,24162467 ! neural tube development GO:0021915 50 36 0,000 0,22625742 0,24756997 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,22625742 0,24745224 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,22625742 0,24733463 ! glucan metabolic process GO:0044042 49 36 0,000 0,22625742 0,24721713 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,23175691 0,25310584 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,23175691 0,25298571 ! ion transmembrane transport GO:0034220 56 37 0,000 0,23175691 0,2528657 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,23175691 0,2527458 ! amino acid activation GO:0043038 52 37 0,000 0,23175691 0,25262601 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,23175691 0,25250634 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,23721762 0,25833359 ! gliogenesis GO:0042063 71 38 0,000 0,23721762 0,25821133 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,23721762 0,25808918 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,23721762 0,25796715 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,23721762 0,25784524 ! phagocytosis GO:0006909 60 38 0,000 0,23721762 0,25772344 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,24263983 0,2634899 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,24263983 0,26336556 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,24263983 0,26324133 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,24263983 0,26311721 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,24263983 0,26299322 ! cell growth GO:0016049 61 39 0,000 0,24263983 0,26286934 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,24802381 0,26857568 ! response to calcium ion GO:0051592 58 40 0,000 0,24802381 0,2684493 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,24802381 0,26832303 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,24802381 0,26819687 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,24802381 0,26807084 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,24802381 0,26794493 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,24802381 0,26781913 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,24802381 0,26769346 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,24802381 0,2675679 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,25336981 0,27320702 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,25336981 0,27307899 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,25336981 0,27295109 ! striated muscle contraction GO:0006941 62 41 0,000 0,25336981 0,2728233 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,25336981 0,27269563 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,25867812 0,27827861 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,25867812 0,27814851 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,25867812 0,27801854 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,25867812 0,27788868 ! neuromuscular process GO:0050905 79 43 0,000 0,26394898 0,28341861 ! tRNA processing GO:0008033 49 43 0,000 0,26394898 0,28328636 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,26394898 0,28315423 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,26918267 0,2886341 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,26918267 0,2884996 ! glycolysis GO:0006096 53 44 0,000 0,26918267 0,28836523 ! regulation of ion transport GO:0043269 57 44 0,000 0,26918267 0,28823098 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,26918267 0,28809686 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,26918267 0,28796286 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,26918267 0,28782899 ! RNA catabolic process GO:0006401 64 45 0,000 0,27437945 0,29324941 ! regulation of translational initiation GO:0006446 64 45 0,000 0,27437945 0,29311321 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,27437945 0,29297713 ! cell recognition GO:0008037 58 45 0,000 0,27437945 0,29284117 ! cell maturation GO:0048469 60 45 0,000 0,27437945 0,29270535 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,27953956 0,29807186 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,27953956 0,29793373 ! cell redox homeostasis GO:0045454 63 46 0,000 0,27953956 0,29779574 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,27953956 0,29765787 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,27953956 0,29752013 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,28466328 0,30283328 ! viral infectious cycle GO:0019058 71 47 0,000 0,28466328 0,30269327 ! endocrine system development GO:0035270 83 47 0,000 0,28466328 0,30255339 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,28466328 0,30241365 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,28466328 0,30227403 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,28466328 0,30213454 ! chloride transport GO:0006821 67 48 0,000 0,28975085 0,3073925 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,28975085 0,30725078 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,28975085 0,30710919 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,28975085 0,30696773 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,28975085 0,3068264 ! regulation of endocytosis GO:0030100 63 48 0,000 0,28975085 0,3066852 ! nuclear export GO:0051168 69 48 0,000 0,28975085 0,30654414 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,28975085 0,3064032 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,29480252 0,31160193 ! sensory perception of smell GO:0007608 61 49 0,000 0,29480252 0,3114588 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,29480252 0,31131579 ! RNA elongation GO:0006354 62 49 0,000 0,29480252 0,31117292 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,29480252 0,31103018 ! regulation of actin filament length GO:0030832 72 50 0,000 0,29981855 0,31617729 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,29981855 0,31603239 ! proton transport GO:0015992 75 50 0,000 0,29981855 0,31588762 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,29981855 0,31574298 ! hydrogen transport GO:0006818 77 51 0,000 0,30479919 0,32084126 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,30479919 0,32069449 ! adult behavior GO:0030534 80 51 0,000 0,30479919 0,32054785 ! transition metal ion transport GO:0000041 74 52 0,000 0,30974469 0,32559999 ! regulation of cellular component size GO:0032535 74 52 0,000 0,30974469 0,32545125 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,30974469 0,32530264 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,30974469 0,32515417 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,31465528 0,33015837 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,31465528 0,33000782 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,31953122 0,33496892 ! glucose catabolic process GO:0006007 66 54 0,000 0,31953122 0,33481631 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,31953122 0,33466385 ! detection of external stimulus GO:0009581 66 54 0,000 0,31953122 0,33451152 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,31953122 0,33435933 ! exocytosis GO:0006887 74 55 0,000 0,32437275 0,33927118 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,32437275 0,33911696 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,32437275 0,33896289 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,3291801 0,34383026 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,33395353 0,34865779 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,33395353 0,3484996 ! camera-type eye development GO:0043010 88 57 0,000 0,33395353 0,34834155 ! developmental maturation GO:0021700 75 57 0,000 0,33395353 0,34818364 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,33869325 0,35296533 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,33869325 0,35280547 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,33869325 0,35264576 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,34339952 0,35738412 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,34807257 0,36208363 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,34807257 0,36191994 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,34807257 0,3617564 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,34807257 0,361593 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,34807257 0,36142975 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,35271262 0,36608259 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,35271262 0,36591747 ! extracellular matrix organization GO:0030198 103 61 0,000 0,35271262 0,36575249 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,35271262 0,36558766 ! amine catabolic process GO:0009310 90 62 0,000 0,35731991 0,37019631 ! neurotransmitter transport GO:0006836 81 62 0,000 0,35731991 0,37002963 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,35731991 0,3698631 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,36189467 0,37442994 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,36189467 0,37426158 ! appendage morphogenesis GO:0035107 93 64 0,000 0,36643713 0,37878894 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,36643713 0,37861878 ! hexose catabolic process GO:0019320 82 64 0,000 0,36643713 0,37844877 ! appendage development GO:0048736 94 65 0,000 0,37094751 0,38293504 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,37094751 0,38276325 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,37094751 0,3825916 ! activation of immune response GO:0002253 83 65 0,000 0,37094751 0,38242011 ! antigen processing and presentation GO:0019882 96 66 0,000 0,37542604 0,38686375 ! regulation of immune effector process GO:0002697 101 66 0,000 0,37542604 0,3866905 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,38428843 0,39564162 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,38428843 0,3954646 ! inorganic anion transport GO:0015698 93 68 0,000 0,38428843 0,39528774 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,38867273 0,39961881 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,39302606 0,40391418 ! eye development GO:0001654 111 70 0,000 0,39302606 0,40373378 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,39302606 0,40355354 ! muscle cell differentiation GO:0042692 104 71 0,000 0,39734864 0,40780985 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,39734864 0,40762795 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,39734864 0,40744622 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,41013401 0,42036909 ! digestion GO:0007586 97 74 0,000 0,41013401 0,42018184 ! protein import into nucleus GO:0006606 118 74 0,000 0,41013401 0,41999476 ! nuclear import GO:0051170 121 75 0,000 0,41433573 0,42410866 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,41433573 0,42392 ! amine biosynthetic process GO:0009309 97 76 0,000 0,41850775 0,42799814 ! tRNA metabolic process GO:0006399 95 76 0,000 0,41850775 0,42780792 ! response to unfolded protein GO:0006986 99 76 0,000 0,41850775 0,42761787 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,42265029 0,43165882 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,42265029 0,43146722 ! protein ubiquitination GO:0016567 125 77 0,000 0,42265029 0,4312758 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,42265029 0,43108455 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,42676355 0,43508695 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,42676355 0,43489418 ! cellular respiration GO:0045333 107 79 0,000 0,43084774 0,43886174 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,43084774 0,43866747 ! regulation of lyase activity GO:0051339 133 79 0,000 0,43084774 0,43847337 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,43084774 0,43827944 ! chromatin assembly GO:0031497 102 80 0,000 0,43490307 0,44220914 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,43490307 0,44201373 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,43490307 0,44181849 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,43490307 0,44162343 ! mRNA transport GO:0051028 121 81 0,000 0,43892974 0,44551562 ! detection of stimulus GO:0051606 108 82 0,000 0,44292794 0,4493755 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,44689788 0,45320332 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,45083975 0,45699931 ! sterol metabolic process GO:0016125 120 84 0,000 0,45083975 0,45679799 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,45475376 0,46056083 ! transcription initiation GO:0006352 118 85 0,000 0,45475376 0,46035812 ! nucleosome organization GO:0034728 114 87 0,000 0,46249894 0,46799277 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,46249894 0,46778697 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,46249894 0,46758135 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,46249894 0,46737591 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,46633051 0,47104092 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,46633051 0,47083414 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,46633051 0,47062755 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,46633051 0,47042113 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,47013499 0,47405106 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,47391256 0,47765069 ! RNA localization GO:0006403 135 91 0,000 0,47766341 0,48122026 ! ATP metabolic process GO:0046034 137 91 0,000 0,47766341 0,48100956 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,48138773 0,48454783 ! positive regulation of immune response GO:0050778 121 92 0,000 0,48138773 0,48433587 ! DNA recombination GO:0006310 146 92 0,000 0,48138773 0,48412409 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,48508572 0,48762987 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,48508572 0,48741684 ! electron transport chain GO:0022900 123 94 0,000 0,48875754 0,49089186 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,49602345 0,49797204 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,49602345 0,49775478 ! protein maturation GO:0051604 129 96 0,000 0,49602345 0,4975377 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,4996179 0,50092466 ! calcium ion transport GO:0006816 167 99 0,000 0,50673069 0,50783468 ! protein import GO:0017038 156 99 0,000 0,50673069 0,50761349 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,51024938 0,51091579 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,51024938 0,51069346 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,51024938 0,51047132 ! divalent metal ion transport GO:0070838 171 100 0,000 0,51024938 0,51024938