pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6902-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of MAP kinase activity GO:0043406 160 93 10,000 4,214E-12 1,014E-08 ! cellular response to hormone stimulus GO:0032870 167 82 9,000 2,994E-11 3,602E-08 ! organ growth GO:0035265 15 7 4,000 9,967E-11 7,994E-08 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 6,000 1,101E-10 6,625E-08 ! positive regulation of cell migration GO:0030335 126 57 7,000 9,442E-10 4,544E-07 ! positive regulation of cell motion GO:0051272 146 64 7,000 2,448E-09 9,816E-07 ! activation of MAPK activity GO:0000187 115 67 7,000 3,557E-09 1,223E-06 ! insulin receptor signaling pathway GO:0008286 64 26 5,000 5,381E-09 1,618E-06 ! response to hypoxia GO:0001666 171 81 7,000 1,643E-08 4,393E-06 ! response to oxygen levels GO:0070482 176 83 7,000 1,996E-08 4,803E-06 ! negative regulation of transport GO:0051051 153 84 7,000 2,196E-08 4,804E-06 ! negative regulation of hormone secretion GO:0046888 25 17 4,000 2,809E-08 5,632E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 3,075E-08 5,692E-06 GO:0046676|negative regulation of insulin secretion, ! regulation of protein export from nucleus GO:0046825 10 7 3,000 3,075E-08 5,285E-06 ! negative regulation of secretion GO:0051048 63 35 5,000 3,641E-08 5,84E-06 ! DNA integrity checkpoint GO:0031570 75 36 5,000 4,349E-08 6,54E-06 ! response to peptide hormone stimulus GO:0043434 122 61 6,000 4,624E-08 6,544E-06 ! cellular response to insulin stimulus GO:0032869 82 37 5,000 5,168E-08 6,907E-06 ! positive regulation of hormone secretion GO:0046887 32 19 4,000 5,231E-08 6,624E-06 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 3,000 6,124E-08 7,368E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 6,124E-08 7,017E-06 ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,098E-07 1,2E-05 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 1,098E-07 1,148E-05 ! cell cycle checkpoint GO:0000075 137 69 6,000 1,102E-07 1,105E-05 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 1,87E-07 1,8E-05 ! response to insulin stimulus GO:0032868 95 46 5,000 1,999E-07 1,849E-05 ! positive regulation of cell cycle GO:0045787 89 48 5,000 2,595E-07 2,312E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 2,868E-07 2,465E-05 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 4,000 2,868E-07 2,38E-05 GO:0045840|positive regulation of mitosis, ! regulation of angiogenesis GO:0045765 114 52 5,000 4,227E-07 3,39E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 4,257E-07 3,304E-05 GO:0050927|positive regulation of positive chemotaxis, ! regulation of multicellular organism growth GO:0040014 85 55 5,000 5,937E-07 4,464E-05 ! cell junction assembly GO:0034329 78 30 4,000 6,104E-07 4,451E-05 ! regulation of cell cycle process GO:0010564 149 90 6,000 6,926E-07 4,901E-05 ! triglyceride metabolic process GO:0006641 43 31 4,000 7,246E-07 4,981E-05 ! negative regulation of multicellular organismal process GO:0051241 166 93 6,000 8,661E-07 5,789E-05 ! DNA damage checkpoint GO:0000077 71 33 4,000 1,003E-06 6,523E-05 ! regulation of mitosis GO:0007088 105 63 5,000 1,342E-06 8,496E-05 GO:0051783|regulation of nuclear division, ! regulation of smooth muscle cell proliferation GO:0048660 59 35 4,000 1,36E-06 8,39E-05 ! neutral lipid metabolic process GO:0006638 50 35 4,000 1,36E-06 8,18E-05 GO:0006639|acylglycerol metabolic process, ! cell junction organization GO:0034330 86 36 4,000 1,572E-06 9,227E-05 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 1,631E-06 9,345E-05 ! glycerol ether metabolic process GO:0006662 53 37 4,000 1,81E-06 1,013E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 1,935E-06 1,058E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 2,003E-06 1,071E-04 ! neutrophil chemotaxis GO:0030593 27 17 3,000 2,003E-06 1,048E-04 ! negative regulation of blood coagulation GO:0030195 24 17 3,000 2,003E-06 1,025E-04 ! carbohydrate homeostasis GO:0033500 53 38 4,000 2,075E-06 1,04E-04 GO:0042593|glucose homeostasis, ! organic ether metabolic process GO:0018904 55 39 4,000 2,369E-06 1,163E-04 ! cell-substrate junction assembly GO:0007044 54 18 3,000 2,564E-06 1,234E-04 ! regulation of hormone secretion GO:0046883 62 40 4,000 2,696E-06 1,272E-04 ! neural nucleus development GO:0048857 14 6 2,000 3,249E-06 1,503E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 4,026E-06 1,827E-04 ! negative regulation of coagulation GO:0050819 29 20 3,000 4,026E-06 1,794E-04 ! branching morphogenesis of a tube GO:0048754 97 45 4,000 4,895E-06 2,142E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 4,895E-06 2,103E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 4,951E-06 2,09E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of phosphorylation GO:0042327 129 79 5,000 5,104E-06 2,117E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 5,468E-06 2,23E-04 ! wound healing, spreading of epidermal cells GO:0035313 14 7 2,000 5,663E-06 2,271E-04 ! fibrinolysis GO:0042730 10 7 2,000 5,663E-06 2,234E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 5,663E-06 2,198E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 5,906E-06 2,255E-04 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of chemotaxis GO:0050920 40 22 3,000 6,026E-06 2,265E-04 ! regulation of behavior GO:0050795 43 24 3,000 8,678E-06 3,212E-04 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 9,024E-06 3,29E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 9,024E-06 3,241E-04 ! morphogenesis of a branching structure GO:0001763 111 52 4,000 1,009E-05 3,572E-04 ! regulation of insulin secretion GO:0050796 37 25 3,000 1,029E-05 3,587E-04 ! regulation of blood coagulation GO:0030193 40 25 3,000 1,029E-05 3,536E-04 ! response to UV GO:0009411 104 53 4,000 1,11E-05 3,76E-04 ! regulation of membrane potential GO:0042391 164 93 5,000 1,314E-05 4,389E-04 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 2,000 1,348E-05 4,443E-04 GO:0010469|regulation of receptor activity, ! middle ear morphogenesis GO:0042474 14 9 2,000 1,348E-05 4,383E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,348E-05 4,325E-04 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 3,000 1,415E-05 4,479E-04 ! positive regulation of organelle organization GO:0010638 100 56 4,000 1,458E-05 4,554E-04 ! regulation of protein localization GO:0032880 176 97 5,000 1,672E-05 5,158E-04 ! positive regulation of secretion GO:0051047 95 59 4,000 1,885E-05 5,741E-04 ! regulation of peptide secretion GO:0002791 47 29 3,000 1,898E-05 5,71E-04 ! regulation of coagulation GO:0050818 46 29 3,000 1,898E-05 5,639E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,918E-05 5,628E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 1,918E-05 5,56E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,918E-05 5,494E-04 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 2,047E-05 5,795E-04 ! regulation of heart contraction GO:0008016 110 60 4,000 2,047E-05 5,727E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,627E-05 7,264E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,627E-05 7,182E-04 GO:0010829|negative regulation of glucose transport, ! multicellular organism reproduction GO:0032504 111 64 4,000 2,808E-05 7,59E-04 GO:0048609|reproductive process in a multicellular organism, ! leukocyte chemotaxis GO:0030595 50 33 3,000 3,215E-05 8,595E-04 GO:0060326|cell chemotaxis, ! regulation of B cell proliferation GO:0030888 20 12 2,000 3,488E-05 9,222E-04 ! focal adhesion formation GO:0048041 35 12 2,000 3,488E-05 9,122E-04 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 3,488E-05 9,024E-04 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 3,509E-05 8,983E-04 ! negative regulation of cell growth GO:0030308 132 67 4,000 3,509E-05 8,888E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 3,771E-05 9,451E-04 ! negative regulation of cell size GO:0045792 134 69 4,000 4,048E-05 1,004E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 4,973E-05 1,221E-03 ! nucleus organization GO:0006997 67 38 3,000 5,677E-05 1,38E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 5,724E-05 1,377E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 5,724E-05 1,364E-03 GO:0060675|ureteric bud morphogenesis, ! cell-matrix adhesion GO:0007160 163 75 4,000 6,053E-05 1,428E-03 ! negative regulation of bone remodeling GO:0046851 33 15 2,000 7,127E-05 1,665E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 7,127E-05 1,649E-03 ! hormone-mediated signaling GO:0009755 74 41 3,000 7,688E-05 1,762E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 8,461E-05 1,921E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 2,000 8,736E-05 1,964E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 8,736E-05 1,946E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 8,736E-05 1,928E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 2,000 8,736E-05 1,911E-03 ! cell-substrate adhesion GO:0031589 171 81 4,000 8,75E-05 1,897E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 9,289E-05 1,996E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,04E-04 2,215E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,056E-04 2,23E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 1,056E-04 2,21E-03 ! leukocyte migration GO:0050900 68 45 3,000 1,112E-04 2,306E-03 ! tube morphogenesis GO:0035239 176 86 4,000 1,163E-04 2,392E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,213E-04 2,472E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 1,213E-04 2,452E-03 ! regulation of protein transport GO:0051223 154 87 4,000 1,229E-04 2,464E-03 GO:0070201|regulation of establishment of protein localization, ! response to retinoic acid GO:0032526 26 18 2,000 1,263E-04 2,511E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,434E-04 2,827E-03 ! response to vitamin A GO:0033189 27 19 2,000 1,493E-04 2,921E-03 ! plasma membrane fusion GO:0045026 28 19 2,000 1,493E-04 2,898E-03 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 1,493E-04 2,874E-03 ! response to vitamin GO:0033273 31 20 2,000 1,75E-04 3,341E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,75E-04 3,315E-03 ! negative regulation of angiogenesis GO:0016525 45 20 2,000 1,75E-04 3,289E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,75E-04 3,263E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,75E-04 3,238E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 1,818E-04 3,338E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,86E-04 3,39E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 1,961E-04 3,547E-03 ! positive regulation of growth GO:0045927 90 52 3,000 1,961E-04 3,52E-03 ! cartilage development GO:0051216 90 52 3,000 1,961E-04 3,494E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,033E-04 3,597E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,033E-04 3,571E-03 ! regulation of vasoconstriction GO:0019229 39 21 2,000 2,033E-04 3,545E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,033E-04 3,519E-03 ! response to cytokine stimulus GO:0034097 63 21 2,000 2,033E-04 3,494E-03 ! hormone metabolic process GO:0042445 157 97 4,000 2,05E-04 3,499E-03 ! interphase GO:0051325 213 98 4,000 2,151E-04 3,645E-03 ! activation of phospholipase C activity GO:0007202 103 54 3,000 2,271E-04 3,821E-03 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,345E-04 3,917E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,345E-04 3,89E-03 ! ureteric bud development GO:0001657 43 22 2,000 2,345E-04 3,864E-03 ! renal system process GO:0003014 41 22 2,000 2,345E-04 3,838E-03 ! positive regulation of phospholipase activity GO:0010518 104 55 3,000 2,439E-04 3,964E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 2,439E-04 3,938E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 2,685E-04 4,307E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,685E-04 4,279E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 2,8E-04 4,433E-03 ! regulation of phospholipase activity GO:0010517 106 57 3,000 2,8E-04 4,404E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,8E-04 4,375E-03 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 1,000 2,987E-04 4,637E-03 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,987E-04 4,607E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 2,987E-04 4,578E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,987E-04 4,549E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 2,987E-04 4,52E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,987E-04 4,492E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 2,987E-04 4,464E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,987E-04 4,436E-03 ! microvillus organization GO:0032528 7 5 1,000 2,987E-04 4,409E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 2,987E-04 4,382E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 1,000 2,987E-04 4,356E-03 ! muscle cell migration GO:0014812 8 5 1,000 2,987E-04 4,329E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,987E-04 4,304E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,987E-04 4,278E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,987E-04 4,253E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,987E-04 4,228E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,987E-04 4,203E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,987E-04 4,178E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 2,987E-04 4,154E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,987E-04 4,13E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,987E-04 4,107E-03 ! stem cell division GO:0017145 11 5 1,000 2,987E-04 4,083E-03 GO:0048103|somatic stem cell division, ! positive regulation of lipase activity GO:0060193 108 58 3,000 2,995E-04 4,071E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,057E-04 4,132E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,413E-04 4,587E-03 ! myelination GO:0042552 45 25 2,000 3,459E-04 4,624E-03 ! ear development GO:0043583 103 62 3,000 3,871E-04 5,146E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 3,895E-04 5,149E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 4,364E-04 5,738E-03 ! response to toxin GO:0009636 47 27 2,000 4,364E-04 5,706E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 4,364E-04 5,676E-03 ! toxin metabolic process GO:0009404 11 6 1,000 4,464E-04 5,775E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,464E-04 5,744E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! vascular smooth muscle contraction GO:0014829 13 6 1,000 4,464E-04 5,713E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 4,464E-04 5,683E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! neuron apoptosis GO:0051402 9 6 1,000 4,464E-04 5,653E-03 ! male sex determination GO:0030238 15 6 1,000 4,464E-04 5,624E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 4,464E-04 5,594E-03 GO:0051653|spindle localization, ! purine base biosynthetic process GO:0009113 17 6 1,000 4,464E-04 5,565E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 4,464E-04 5,537E-03 ! progesterone metabolic process GO:0042448 10 6 1,000 4,464E-04 5,508E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 4,464E-04 5,48E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,464E-04 5,452E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 4,868E-04 5,915E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 4,868E-04 5,886E-03 ! regulation of lipase activity GO:0060191 130 68 3,000 5,508E-04 6,626E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 5,984E-04 7,163E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 5,984E-04 7,128E-03 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 5,984E-04 7,093E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 5,984E-04 7,058E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,227E-04 7,309E-03 ! mRNA stabilization GO:0048255 18 7 1,000 6,227E-04 7,273E-03 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 6,227E-04 7,238E-03 ! positive regulation of heart rate GO:0010460 10 7 1,000 6,227E-04 7,203E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 6,227E-04 7,169E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! phasic smooth muscle contraction GO:0014821 12 7 1,000 6,227E-04 7,135E-03 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 6,227E-04 7,101E-03 ! glycerol ether catabolic process GO:0044269 12 7 1,000 6,227E-04 7,068E-03 GO:0046464|acylglycerol catabolic process, ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,227E-04 7,034E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 6,227E-04 7,002E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 6,227E-04 6,969E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 6,227E-04 6,937E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,227E-04 6,905E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 6,227E-04 6,873E-03 ! diuresis GO:0030146 12 7 1,000 6,227E-04 6,842E-03 GO:0030147|natriuresis, ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 6,227E-04 6,811E-03 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 1,000 6,227E-04 6,78E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 6,227E-04 6,749E-03 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 6,227E-04 6,719E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 6,84E-04 7,347E-03 ! metanephros development GO:0001656 74 32 2,000 7,252E-04 7,755E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 7,252E-04 7,721E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 7,252E-04 7,687E-03 ! hindbrain development GO:0030902 61 32 2,000 7,252E-04 7,653E-03 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 7,979E-04 8,383E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 8,273E-04 8,654E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 8,273E-04 8,617E-03 ! neutral lipid catabolic process GO:0046461 13 8 1,000 8,273E-04 8,58E-03 ! succinate metabolic process GO:0006105 14 8 1,000 8,273E-04 8,543E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,273E-04 8,507E-03 ! glycerolipid catabolic process GO:0046503 13 8 1,000 8,273E-04 8,47E-03 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 8,273E-04 8,434E-03 ! pigment granule organization GO:0048753 16 8 1,000 8,273E-04 8,399E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 8,273E-04 8,364E-03 ! melanin metabolic process GO:0006582 15 8 1,000 8,273E-04 8,329E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 8,273E-04 8,294E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 8,273E-04 8,259E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,273E-04 8,225E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 8,273E-04 8,191E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,273E-04 8,158E-03 ! response to UV-B GO:0010224 16 8 1,000 8,273E-04 8,125E-03 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 8,273E-04 8,092E-03 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 8,273E-04 8,059E-03 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 8,679E-04 8,42E-03 ! blood coagulation GO:0007596 146 78 3,000 9,245E-04 8,933E-03 GO:0050817|coagulation, ! regulation of muscle development GO:0048634 70 35 2,000 9,455E-04 9,099E-03 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 9,455E-04 9,063E-03 ! calcium-mediated signaling GO:0019722 62 35 2,000 9,455E-04 9,027E-03 ! activation of protein kinase activity GO:0032147 147 79 3,000 9,696E-04 9,221E-03 ! mitotic sister chromatid segregation GO:0000070 57 36 2,000 1,027E-03 9,731E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,027E-03 9,692E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,06E-03 9,961E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,06E-03 9,922E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,06E-03 9,884E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,06E-03 9,846E-03 ! T cell selection GO:0045058 23 9 1,000 1,06E-03 9,808E-03 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,06E-03 9,77E-03 GO:0006600|creatine metabolic process, ! behavioral fear response GO:0001662 22 9 1,000 1,06E-03 9,733E-03 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,06E-03 9,696E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,06E-03 9,659E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,06E-03 9,623E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,06E-03 9,586E-03 ! renal water homeostasis GO:0003091 14 9 1,000 1,06E-03 9,551E-03 ! purine base metabolic process GO:0006144 21 9 1,000 1,06E-03 9,515E-03 ! regulation of muscle adaptation GO:0043502 14 9 1,000 1,06E-03 9,48E-03 ! sister chromatid segregation GO:0000819 58 37 2,000 1,113E-03 9,922E-03 ! regulation of protein stability GO:0031647 73 37 2,000 1,113E-03 9,885E-03 ! pigment metabolic process GO:0042440 80 37 2,000 1,113E-03 9,849E-03 ! response to nutrient GO:0007584 125 82 3,000 1,114E-03 9,822E-03 ! hemostasis GO:0007599 158 84 3,000 1,219E-03 0,01070374 ! mammary gland development GO:0030879 86 39 2,000 1,299E-03 0,01136537 ! ear morphogenesis GO:0042471 60 39 2,000 1,299E-03 0,01132419 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,299E-03 0,01128331 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,32E-03 0,01142428 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,32E-03 0,01138333 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,32E-03 0,01134268 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,32E-03 0,01130231 ! lung alveolus development GO:0048286 26 10 1,000 1,32E-03 0,01126223 ! B cell proliferation GO:0042100 18 10 1,000 1,32E-03 0,01122244 ! nucleobase biosynthetic process GO:0046112 24 10 1,000 1,32E-03 0,01118292 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 1,32E-03 0,01114368 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,32E-03 0,01110472 ! regulation of bone resorption GO:0045124 25 10 1,000 1,32E-03 0,01106603 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,32E-03 0,0110276 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,32E-03 0,01098944 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,32E-03 0,01095155 ! multicellular organismal water homeostasis GO:0050891 15 10 1,000 1,32E-03 0,01091392 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,32E-03 0,01087654 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,32E-03 0,01083942 ! response to nicotine GO:0035094 20 10 1,000 1,32E-03 0,01080255 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,32E-03 0,01076593 ! localization within membrane GO:0051668 20 10 1,000 1,32E-03 0,01072956 ! mitochondrion organization GO:0007005 148 86 3,000 1,33E-03 0,01077582 ! mesenchymal cell development GO:0014031 87 40 2,000 1,399E-03 0,01129296 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,448E-03 0,01165423 ! gland development GO:0048732 206 88 3,000 1,448E-03 0,01161538 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 2,000 1,503E-03 0,01201455 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,503E-03 0,01197476 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,503E-03 0,01193524 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 1,503E-03 0,01189598 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,51E-03 0,01191182 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,608E-03 0,01263945 ! blood vessel remodeling GO:0001974 29 11 1,000 1,608E-03 0,01259828 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,608E-03 0,01255738 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,608E-03 0,01251674 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,608E-03 0,01247636 ! negative regulation of ossification GO:0030279 26 11 1,000 1,608E-03 0,01243624 ! vasoconstriction GO:0042310 18 11 1,000 1,608E-03 0,01239638 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,608E-03 0,01235678 ! oocyte differentiation GO:0009994 18 11 1,000 1,608E-03 0,01231743 ! thymus development GO:0048538 27 11 1,000 1,608E-03 0,01227832 ! regulation of embryonic development GO:0045995 27 11 1,000 1,608E-03 0,01223947 ! response to reactive oxygen species GO:0000302 67 42 2,000 1,612E-03 0,01223628 ! glucose transport GO:0015758 65 43 2,000 1,726E-03 0,01305993 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,726E-03 0,01301899 ! hexose transport GO:0008645 67 44 2,000 1,845E-03 0,01387196 GO:0015749|monosaccharide transport, ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,922E-03 0,0144063 ! virus-host interaction GO:0019048 29 12 1,000 1,922E-03 0,01436156 ! fear response GO:0042596 26 12 1,000 1,922E-03 0,0143171 ! cranial nerve development GO:0021545 20 12 1,000 1,922E-03 0,01427291 ! histone acetylation GO:0016573 26 12 1,000 1,922E-03 0,01422899 ! histone methylation GO:0016571 26 12 1,000 1,922E-03 0,01418534 ! autonomic nervous system development GO:0048483 24 12 1,000 1,922E-03 0,01414196 ! gland morphogenesis GO:0022612 29 12 1,000 1,922E-03 0,01409885 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,922E-03 0,01405599 ! T cell homeostasis GO:0043029 25 12 1,000 1,922E-03 0,0140134 ! spleen development GO:0048536 22 12 1,000 1,922E-03 0,01397106 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,922E-03 0,01392898 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,922E-03 0,01388715 ! positive regulation of defense response GO:0031349 76 47 2,000 2,232E-03 0,01607664 ! vascular process in circulatory system GO:0003018 80 47 2,000 2,232E-03 0,01602865 ! regulation of JNK cascade GO:0046328 94 47 2,000 2,232E-03 0,01598094 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,263E-03 0,01615867 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,263E-03 0,01611086 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 1,000 2,263E-03 0,01606333 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,263E-03 0,01601609 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,263E-03 0,01596912 ! cell wall macromolecule catabolic process GO:0016998 14 13 1,000 2,263E-03 0,01592243 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,263E-03 0,01587601 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,263E-03 0,01582986 ! mitochondrial transport GO:0006839 82 48 2,000 2,371E-03 0,016535 ! cellular component disassembly GO:0022411 86 48 2,000 2,371E-03 0,01648721 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 2,371E-03 0,0164397 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,371E-03 0,01639246 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,371E-03 0,01634549 ! regulation of action potential GO:0001508 95 49 2,000 2,515E-03 0,01729207 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,515E-03 0,0172428 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,631E-03 0,01798322 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,631E-03 0,01793228 ! regulation of heart rate GO:0002027 24 14 1,000 2,631E-03 0,01788162 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,631E-03 0,01783125 ! response to gamma radiation GO:0010332 28 14 1,000 2,631E-03 0,01778116 ! cAMP biosynthetic process GO:0006171 23 14 1,000 2,631E-03 0,01773135 ! regulation of RNA stability GO:0043487 32 14 1,000 2,631E-03 0,01768182 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,631E-03 0,01763257 ! cell wall macromolecule metabolic process GO:0044036 15 14 1,000 2,631E-03 0,01758359 ! histone modification GO:0016570 91 50 2,000 2,665E-03 0,01776371 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,665E-03 0,01771464 ! embryonic skeletal system development GO:0048706 85 51 2,000 2,821E-03 0,01869466 ! chromatin remodeling GO:0006338 109 51 2,000 2,821E-03 0,0186433 ! regulation of cell shape GO:0008360 125 51 2,000 2,821E-03 0,01859222 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 2,821E-03 0,01854143 ! membrane fusion GO:0006944 110 52 2,000 2,981E-03 0,0195443 ! covalent chromatin modification GO:0016569 101 52 2,000 2,981E-03 0,01949119 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,025E-03 0,01972242 ! positive regulation of cell size GO:0045793 27 15 1,000 3,025E-03 0,01966912 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,025E-03 0,0196161 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,025E-03 0,01956337 ! water homeostasis GO:0030104 27 15 1,000 3,025E-03 0,01951092 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 1,000 3,025E-03 0,01945875 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,025E-03 0,01940686 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 2,000 3,147E-03 0,02014 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,444E-03 0,02198197 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,444E-03 0,02192381 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 3,444E-03 0,02186597 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! DNA replication initiation GO:0006270 27 16 1,000 3,444E-03 0,02180843 ! aging GO:0007568 103 55 2,000 3,497E-03 0,02208092 ! regulation of DNA replication GO:0006275 101 56 2,000 3,68E-03 0,02317648 ! regulation of bone remodeling GO:0046850 137 57 2,000 3,869E-03 0,02430246 ! metencephalon development GO:0022037 30 17 1,000 3,89E-03 0,0243705 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,89E-03 0,0243072 ! signal complex assembly GO:0007172 41 17 1,000 3,89E-03 0,02424422 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 3,89E-03 0,02418158 ! regulation of viral genome replication GO:0045069 28 17 1,000 3,89E-03 0,02411925 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,89E-03 0,02405725 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,89E-03 0,02399556 ! regulation of protein binding GO:0043393 33 17 1,000 3,89E-03 0,0239342 ! nucleobase metabolic process GO:0009112 37 17 1,000 3,89E-03 0,02387314 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 3,89E-03 0,02381239 ! regulation of tissue remodeling GO:0034103 140 58 2,000 4,063E-03 0,02481279 ! skeletal system morphogenesis GO:0048705 105 59 2,000 4,264E-03 0,02597148 ! DNA catabolic process GO:0006308 86 59 2,000 4,264E-03 0,02590589 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,36E-03 0,02642338 ! memory GO:0007613 31 18 1,000 4,36E-03 0,02635699 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,36E-03 0,02629093 GO:0050886|endocrine process, ! patterning of blood vessels GO:0001569 39 18 1,000 4,36E-03 0,0262252 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,36E-03 0,0261598 ! glutamine metabolic process GO:0006541 29 18 1,000 4,36E-03 0,02609473 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,36E-03 0,02602998 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,36E-03 0,02596554 ! nerve development GO:0021675 28 18 1,000 4,36E-03 0,02590143 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,47E-03 0,02649126 ! kidney development GO:0001822 122 60 2,000 4,47E-03 0,02642617 ! mesoderm development GO:0007498 119 61 2,000 4,683E-03 0,02761399 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 4,855E-03 0,02856219 ! lipid phosphorylation GO:0046834 35 19 1,000 4,855E-03 0,02849253 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,855E-03 0,02842321 ! mitotic chromosome condensation GO:0007076 34 19 1,000 4,855E-03 0,02835422 ! actin filament bundle formation GO:0051017 42 19 1,000 4,855E-03 0,02828556 ! neuromuscular junction development GO:0007528 34 19 1,000 4,855E-03 0,02821724 ! peptide cross-linking GO:0018149 37 19 1,000 4,855E-03 0,02814925 ! cellular pigmentation GO:0033059 36 19 1,000 4,855E-03 0,02808158 ! cell-cell junction organization GO:0045216 35 19 1,000 4,855E-03 0,02801424 ! peptide hormone secretion GO:0030072 31 19 1,000 4,855E-03 0,02794722 ! regulation of homeostatic process GO:0032844 134 62 2,000 4,901E-03 0,02814326 ! nucleoside monophosphate metabolic process GO:0009123 107 63 2,000 5,126E-03 0,02936217 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 5,356E-03 0,03061018 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,375E-03 0,03064728 ! cAMP metabolic process GO:0046058 36 20 1,000 5,375E-03 0,03057483 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,375E-03 0,03050272 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 1,000 5,375E-03 0,03043095 ! response to alkaloid GO:0043279 38 20 1,000 5,375E-03 0,03035952 ! body fluid secretion GO:0007589 31 20 1,000 5,375E-03 0,03028842 ! peptide secretion GO:0002790 35 20 1,000 5,375E-03 0,03021765 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,375E-03 0,03014721 ! negative regulation of translation GO:0017148 29 20 1,000 5,375E-03 0,0300771 ! actin filament organization GO:0007015 148 66 2,000 5,836E-03 0,03257749 ! secondary metabolic process GO:0019748 116 66 2,000 5,836E-03 0,03250208 ! hormone secretion GO:0046879 38 21 1,000 5,92E-03 0,03289387 ! ovarian follicle development GO:0001541 35 21 1,000 5,92E-03 0,03281808 ! smooth muscle contraction GO:0006939 46 21 1,000 5,92E-03 0,03274264 ! cell aging GO:0007569 44 21 1,000 5,92E-03 0,03266754 ! oogenesis GO:0048477 36 21 1,000 5,92E-03 0,03259278 ! gut development GO:0048565 39 21 1,000 5,92E-03 0,03251837 ! regulation of cellular response to stress GO:0080135 128 67 2,000 6,085E-03 0,03334932 ! lung development GO:0030324 144 67 2,000 6,085E-03 0,03327352 ! chromosome segregation GO:0007059 113 67 2,000 6,085E-03 0,03319807 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 6,488E-03 0,03531887 ! glutamate signaling pathway GO:0007215 41 22 1,000 6,488E-03 0,03523914 ! regeneration GO:0031099 41 22 1,000 6,488E-03 0,03515977 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 6,488E-03 0,03508076 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 6,488E-03 0,03500211 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 6,488E-03 0,0349238 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 6,488E-03 0,03484585 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,488E-03 0,03476824 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,488E-03 0,03469098 ! urogenital system development GO:0001655 137 69 2,000 6,602E-03 0,03522089 ! respiratory tube development GO:0030323 150 70 2,000 6,87E-03 0,03656999 ! positive regulation of DNA replication GO:0045740 43 23 1,000 7,081E-03 0,03760742 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 7,081E-03 0,03752458 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,081E-03 0,03744211 ! leukocyte adhesion GO:0007159 50 23 1,000 7,081E-03 0,03736 ! response to ethanol GO:0045471 46 23 1,000 7,081E-03 0,03727825 ! sex determination GO:0007530 47 23 1,000 7,081E-03 0,03719686 ! regulation of viral reproduction GO:0050792 38 23 1,000 7,081E-03 0,03711582 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 7,081E-03 0,03703513 ! platelet activation GO:0030168 37 23 1,000 7,081E-03 0,0369548 ! hormone transport GO:0009914 40 23 1,000 7,081E-03 0,03687481 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 7,145E-03 0,03712746 ! carbohydrate transport GO:0008643 110 72 2,000 7,426E-03 0,03850398 ! respiratory system development GO:0060541 153 72 2,000 7,426E-03 0,03842118 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 7,697E-03 0,0397383 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 7,697E-03 0,0396532 ! multicellular organismal response to stress GO:0033555 49 24 1,000 7,697E-03 0,03956847 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 7,697E-03 0,03948411 ! lymphocyte proliferation GO:0046651 48 24 1,000 7,697E-03 0,0394001 ! membrane depolarization GO:0051899 39 24 1,000 7,697E-03 0,03931645 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 7,697E-03 0,03923315 ! leukocyte homeostasis GO:0001776 44 24 1,000 7,697E-03 0,0391502 ! protein tetramerization GO:0051262 52 24 1,000 7,697E-03 0,03906761 ! learning or memory GO:0007611 147 73 2,000 7,713E-03 0,03906783 ! regulation of transcription factor activity GO:0051090 126 74 2,000 8,007E-03 0,04047103 GO:0090046|regulation of transcription regulator activity, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 8,336E-03 0,04204598 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 8,336E-03 0,04195802 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 8,336E-03 0,04187042 ! protein amino acid alkylation GO:0008213 53 25 1,000 8,336E-03 0,04178319 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 1,000 8,336E-03 0,04169633 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 8,336E-03 0,04160982 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 8,336E-03 0,04152367 ! negative regulation of DNA replication GO:0008156 42 25 1,000 8,336E-03 0,04143788 ! chromosome condensation GO:0030261 45 25 1,000 8,336E-03 0,04135244 ! neural crest cell development GO:0014032 54 25 1,000 8,336E-03 0,04126735 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 8,336E-03 0,04118261 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 8,336E-03 0,04109822 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 8,336E-03 0,04101418 ! molting cycle process GO:0022404 50 26 1,000 8,998E-03 0,04418198 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 8,998E-03 0,04409199 ! cellular response to oxidative stress GO:0034599 39 26 1,000 8,998E-03 0,04400237 ! leukocyte proliferation GO:0070661 52 26 1,000 8,998E-03 0,04391312 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 8,998E-03 0,04382423 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 9,574E-03 0,04653752 ! regulation of synaptic transmission GO:0050804 134 79 2,000 9,574E-03 0,04644369 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 9,683E-03 0,04687546 ! spliceosomal snRNP biogenesis GO:0000387 36 27 1,000 9,683E-03 0,04678133 ! protein amino acid acylation GO:0043543 55 27 1,000 9,683E-03 0,04668758 ! male gonad development GO:0008584 44 27 1,000 9,683E-03 0,0465942 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 9,683E-03 0,0465012 ! regulation of chromosome organization GO:0033044 42 27 1,000 9,683E-03 0,04640857 ! T cell activation GO:0042110 168 81 2,000 0,01024798 0,04901919 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01024798 0,04892193 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01039031 0,04950315 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01039031 0,04940532 ! regulation of pH GO:0006885 43 29 1,000 0,01111991 0,05277021 ! respiratory gaseous exchange GO:0007585 57 29 1,000 0,01111991 0,05266633 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01111991 0,05256286 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01111991 0,0524598 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01111991 0,05235714 ! tissue homeostasis GO:0001894 48 29 1,000 0,01111991 0,05225488 GO:0048871|multicellular organismal homeostasis, ! regulation of ligase activity GO:0051340 142 84 2,000 0,01130876 0,05303877 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,01130876 0,05293558 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 0,01187144 0,05546152 ! acute-phase response GO:0006953 49 30 1,000 0,01187144 0,05535404 ! response to heat GO:0009408 50 30 1,000 0,01187144 0,05524697 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01264465 0,05873171 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01264465 0,05861855 ! ovulation cycle process GO:0022602 49 31 1,000 0,01264465 0,05850582 ! peptide transport GO:0015833 55 31 1,000 0,01264465 0,05839353 ! mesoderm formation GO:0001707 69 31 1,000 0,01264465 0,05828166 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01264465 0,05817023 GO:0043433|negative regulation of transcription factor activity, ! regulation of DNA binding GO:0051101 155 88 2,000 0,01281822 0,05885618 ! regulation of neurological system process GO:0031644 148 88 2,000 0,01281822 0,05874407 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01321269 0,06043676 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01343928 0,06135655 ! spindle organization GO:0007051 46 32 1,000 0,01343928 0,06124035 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,01343928 0,06112458 ! ovulation cycle GO:0042698 51 32 1,000 0,01343928 0,06100925 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01343928 0,06089436 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01343928 0,0607799 ! ossification GO:0001503 188 90 2,000 0,01361404 0,06145476 ! bone development GO:0060348 189 91 2,000 0,01402229 0,06317906 ! post-embryonic development GO:0009791 69 33 1,000 0,01425507 0,06410784 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01425507 0,06398824 ! cell fate specification GO:0001708 52 33 1,000 0,01425507 0,06386908 ! regulation of defense response GO:0031347 149 92 2,000 0,01443744 0,06456593 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01509177 0,06736696 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01509177 0,0672422 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01509177 0,06711791 ! female pregnancy GO:0007565 164 94 2,000 0,01528852 0,06786748 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01528852 0,06774249 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01594912 0,07053967 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01594912 0,07041024 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01594912 0,07028128 ! female gonad development GO:0008585 58 35 1,000 0,01594912 0,0701528 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,01661726 0,07295827 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01682688 0,07374401 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01682688 0,07360993 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01682688 0,07347634 ! hormone biosynthetic process GO:0042446 57 36 1,000 0,01682688 0,07334323 ! response to virus GO:0009615 160 98 2,000 0,01707412 0,07428631 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01753796 0,07616666 GO:0060538|skeletal muscle organ development, ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01772479 0,07683936 ! meiosis I GO:0007127 65 37 1,000 0,01772479 0,07670116 ! tissue remodeling GO:0048771 76 37 1,000 0,01772479 0,07656345 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01772479 0,07642624 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01772479 0,07628952 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 0,01772479 0,07615329 ! cell cycle arrest GO:0007050 213 100 2,000 0,01800879 0,07723558 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01864261 0,07981162 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01864261 0,07966986 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01864261 0,0795286 GO:0046660|female sex differentiation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01864261 0,07938784 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 77 39 1,000 0,0195801 0,08323274 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,0195801 0,08308595 ! segmentation GO:0035282 67 39 1,000 0,0195801 0,08293967 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02053702 0,08684019 ! negative regulation of binding GO:0051100 72 40 1,000 0,02053702 0,08668784 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02053702 0,08653603 ! maintenance of protein location GO:0045185 91 40 1,000 0,02053702 0,08638474 ! cytokinesis GO:0000910 72 40 1,000 0,02053702 0,08623398 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02151312 0,0901752 ! T cell differentiation GO:0030217 81 41 1,000 0,02151312 0,09001838 ! female gamete generation GO:0007292 61 41 1,000 0,02151312 0,0898621 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02250817 0,09385555 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 1,000 0,02250817 0,09369317 GO:0050880|regulation of blood vessel size, ! regulation of protein secretion GO:0050708 71 42 1,000 0,02250817 0,09353135 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,02352193 0,09757544 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02352193 0,09740749 ! male sex differentiation GO:0046661 76 44 1,000 0,02455416 0,10150741 ! biopolymer methylation GO:0043414 84 44 1,000 0,02455416 0,1013333 ! B cell differentiation GO:0030183 107 44 1,000 0,02455416 0,10115978 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02455416 0,10098686 ! developmental growth GO:0048589 82 44 1,000 0,02455416 0,10081452 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02455416 0,10064278 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02560464 0,10477001 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02667314 0,10895683 ! pigmentation GO:0043473 100 46 1,000 0,02667314 0,10877215 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02725884 0,11097255 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02725884 0,11078509 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02725884 0,11059827 ! neuron fate determination GO:0048664 7 5 0,000 0,02725884 0,11041208 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02725884 0,11022651 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02725884 0,11004157 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02725884 0,10985724 ! polyol transport GO:0015791 12 5 0,000 0,02725884 0,10967354 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02725884 0,10949044 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02725884 0,10930796 ! response to superoxide GO:0000303 10 5 0,000 0,02725884 0,10912608 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02725884 0,10894481 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02725884 0,10876414 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02725884 0,10858406 ! female meiosis GO:0007143 7 5 0,000 0,02725884 0,10840459 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02725884 0,1082257 ! cobalt ion transport GO:0006824 11 5 0,000 0,02725884 0,10804741 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02725884 0,1078697 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02725884 0,10769257 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02725884 0,10751602 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02725884 0,10734006 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02725884 0,10716467 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02725884 0,10698985 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02725884 0,10681559 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02725884 0,10664191 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02725884 0,10646879 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02725884 0,10629623 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02725884 0,10612423 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02725884 0,10595279 ! negative chemotaxis GO:0050919 14 5 0,000 0,02725884 0,1057819 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02725884 0,10561155 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02725884 0,10544176 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02725884 0,10527251 ! behavioral response to pain GO:0048266 9 5 0,000 0,02725884 0,10510381 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02725884 0,10493564 ! Notch receptor processing GO:0007220 8 5 0,000 0,02725884 0,10476801 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02725884 0,10460092 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02725884 0,10443436 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02725884 0,10426832 ! copulation GO:0007620 9 5 0,000 0,02725884 0,10410282 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02725884 0,10393784 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02725884 0,10377338 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02725884 0,10360944 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02725884 0,10344602 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02725884 0,10328311 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02725884 0,10312072 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02725884 0,10295883 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02725884 0,10279745 ! grooming behavior GO:0007625 6 5 0,000 0,02725884 0,10263658 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02725884 0,10247621 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02725884 0,10231634 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02725884 0,10215697 ! response to protozoan GO:0001562 10 5 0,000 0,02725884 0,1019981 ! lymph vessel development GO:0001945 10 5 0,000 0,02725884 0,10183971 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02725884 0,10168182 ! endochondral ossification GO:0001958 16 5 0,000 0,02725884 0,10152442 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02725884 0,1013675 ! parathyroid gland development GO:0060017 13 5 0,000 0,02725884 0,10121107 ! anagen GO:0042640 6 5 0,000 0,02725884 0,10105512 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02725884 0,10089965 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02725884 0,10074466 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02725884 0,10059015 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02725884 0,1004361 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02725884 0,10028253 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02725884 0,10012943 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02725884 0,09997679 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02725884 0,09982462 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02725884 0,09967291 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02725884 0,09952166 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02725884 0,09937087 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02725884 0,09922054 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02725884 0,09907066 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02725884 0,09892123 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02725884 0,09877225 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02725884 0,09862372 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02725884 0,09847564 ! histidine catabolic process GO:0006548 6 5 0,000 0,02725884 0,098328 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02725884 0,0981808 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02725884 0,09803404 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02725884 0,09788772 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02725884 0,09774184 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02725884 0,09759639 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02725884 0,09745137 ! polyol catabolic process GO:0046174 7 5 0,000 0,02725884 0,09730679 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02725884 0,09716263 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02725884 0,0970189 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02725884 0,09687559 ! mitochondrial fission GO:0000266 8 5 0,000 0,02725884 0,09673271 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02725884 0,09659024 ! mRNA transcription GO:0009299 9 5 0,000 0,02725884 0,0964482 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02725884 0,09630657 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02725884 0,09616536 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02725884 0,09602456 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02725884 0,09588417 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02725884 0,0957442 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02725884 0,09560463 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02725884 0,09546547 ! response to food GO:0032094 6 5 0,000 0,02725884 0,09532671 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02725884 0,09518835 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02725884 0,0950504 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02725884 0,09491284 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02725884 0,09477569 ! forebrain neuron development GO:0021884 13 5 0,000 0,02725884 0,09463893 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02725884 0,09450256 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02725884 0,09436658 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02725884 0,094231 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02725884 0,0940958 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02725884 0,093961 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02725884 0,09382657 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02725884 0,09369254 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02725884 0,09355888 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02725884 0,09342561 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02725884 0,09329271 ! basic amino acid transport GO:0015802 11 5 0,000 0,02725884 0,09316019 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02725884 0,09302805 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02725884 0,09289628 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02725884 0,09276489 ! depyrimidination GO:0045008 10 5 0,000 0,02725884 0,09263386 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02725884 0,09250321 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02725884 0,09237292 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02725884 0,092243 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02725884 0,09211345 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02725884 0,09198426 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02725884 0,09185543 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02725884 0,09172696 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02725884 0,09159885 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02725884 0,0914711 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02725884 0,0913437 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02725884 0,09121666 ! response to arsenic GO:0046685 10 5 0,000 0,02725884 0,09108997 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02725884 0,09096363 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02725884 0,09083764 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02725884 0,090712 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02725884 0,09058671 ! response to cadmium ion GO:0046686 7 5 0,000 0,02725884 0,09046176 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02725884 0,09033716 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02725884 0,0902129 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02725884 0,09008898 ! decidualization GO:0046697 11 5 0,000 0,02725884 0,0899654 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02725884 0,08984216 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02725884 0,08971925 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02725884 0,08959669 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02725884 0,08947445 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02725884 0,08935255 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02725884 0,08923099 ! neural tube patterning GO:0021532 7 5 0,000 0,02725884 0,08910975 ! embryonic cleavage GO:0040016 6 5 0,000 0,02725884 0,08898884 ! peroxisome fission GO:0016559 5 5 0,000 0,02725884 0,08886826 ! histone demethylation GO:0016577 10 5 0,000 0,02725884 0,088748 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02725884 0,08862807 ! mitotic recombination GO:0006312 9 5 0,000 0,02725884 0,08850847 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02725884 0,08838918 ! metaphase plate congression GO:0051310 7 5 0,000 0,02725884 0,08827022 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02725884 0,08815158 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02725884 0,08803326 ! enteric nervous system development GO:0048484 8 5 0,000 0,02725884 0,08791525 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02725884 0,08779756 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02725884 0,08768018 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02725884 0,08756312 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02725884 0,08744637 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02725884 0,08732993 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02725884 0,0872138 ! plasminogen activation GO:0031639 5 5 0,000 0,02725884 0,08709798 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02725884 0,08698246 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02725884 0,08686725 ! metaphase GO:0051323 8 5 0,000 0,02725884 0,08675235 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02725884 0,08663775 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02725884 0,08652345 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02725884 0,08640945 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02725884 0,08629576 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02725884 0,08618236 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02725884 0,08606926 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02725884 0,08595646 ! response to redox state GO:0051775 5 5 0,000 0,02725884 0,08584395 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02725884 0,08573173 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02725884 0,08561981 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02725884 0,08550818 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02725884 0,08539684 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02725884 0,08528579 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02725884 0,08517503 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02725884 0,08506456 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02725884 0,08495437 ! striatum development GO:0021756 9 5 0,000 0,02725884 0,08484447 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02725884 0,08473485 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02725884 0,08462552 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02725884 0,08451646 ! glial cell migration GO:0008347 11 5 0,000 0,02725884 0,08440769 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02725884 0,0842992 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02725884 0,08419098 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02725884 0,08408305 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02725884 0,08397538 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02725884 0,083868 ! neuroprotection GO:0043526 6 5 0,000 0,02725884 0,08376089 ! neural plate development GO:0001840 8 5 0,000 0,02725884 0,08365405 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02725884 0,08354748 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02725884 0,08344119 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02725884 0,08333517 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02725884 0,08322941 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02725884 0,08312392 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02725884 0,0830187 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02725884 0,08291375 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02725884 0,08280906 ! spindle assembly GO:0051225 6 5 0,000 0,02725884 0,08270463 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02725884 0,08260047 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02725884 0,08249657 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02725884 0,08239293 ! drug metabolic process GO:0017144 6 5 0,000 0,02725884 0,08228955 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02725884 0,08218644 ! organ regeneration GO:0031100 7 5 0,000 0,02725884 0,08208357 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02725884 0,08198097 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02725884 0,08187862 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02725884 0,08177653 ! endosome transport GO:0016197 108 47 1,000 0,02775942 0,08317456 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02775942 0,08307111 ! JNK cascade GO:0007254 91 47 1,000 0,02775942 0,08296791 ! methylation GO:0032259 90 47 1,000 0,02775942 0,08286497 ! activation of caspase activity GO:0006919 84 48 1,000 0,02886327 0,08605331 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,02998445 0,08928538 ! peptide metabolic process GO:0006518 76 49 1,000 0,02998445 0,08917501 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02998445 0,08906492 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,02998445 0,0889551 ! regulation of ossification GO:0030278 117 50 1,000 0,03112275 0,09221839 ! inner ear development GO:0048839 79 50 1,000 0,03112275 0,09210496 ! positive regulation of binding GO:0051099 78 51 1,000 0,03227794 0,0954063 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03227794 0,09528923 ! excretion GO:0007588 83 51 1,000 0,03227794 0,09517246 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03227794 0,09505597 ! vesicle organization GO:0016050 107 51 1,000 0,03227794 0,09493976 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03262132 0,09583261 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03262132 0,09571574 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03262132 0,09559915 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03262132 0,09548285 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03262132 0,09536683 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03262132 0,0952511 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03262132 0,09513564 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03262132 0,09502047 ! sleep GO:0030431 13 6 0,000 0,03262132 0,09490557 ! response to oxygen radical GO:0000305 11 6 0,000 0,03262132 0,09479095 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03262132 0,0946766 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03262132 0,09456254 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03262132 0,09444874 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03262132 0,09433522 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03262132 0,09422197 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03262132 0,094109 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03262132 0,09399629 ! forebrain regionalization GO:0021871 8 6 0,000 0,03262132 0,09388386 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03262132 0,09377169 ! male meiosis GO:0007140 7 6 0,000 0,03262132 0,09365979 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03262132 0,09354816 ! response to zinc ion GO:0010043 9 6 0,000 0,03262132 0,09343679 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03262132 0,09332569 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03262132 0,09321485 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03262132 0,09310428 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03262132 0,09299396 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03262132 0,09288391 ! malate metabolic process GO:0006108 11 6 0,000 0,03262132 0,09277412 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03262132 0,09266459 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03262132 0,09255531 ! protein refolding GO:0042026 15 6 0,000 0,03262132 0,0924463 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03262132 0,09233754 ! opsonization GO:0008228 8 6 0,000 0,03262132 0,09222903 ! mating behavior GO:0007617 7 6 0,000 0,03262132 0,09212078 ! neuron remodeling GO:0016322 15 6 0,000 0,03262132 0,09201278 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03262132 0,09190504 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03262132 0,09179755 ! equilibrioception GO:0050957 14 6 0,000 0,03262132 0,09169031 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03262132 0,09158332 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03262132 0,09147658 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03262132 0,09137009 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03262132 0,09126384 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03262132 0,09115785 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03262132 0,09105209 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03262132 0,09094659 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03262132 0,09084133 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03262132 0,09073631 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03262132 0,09063153 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03262132 0,090527 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03262132 0,0904227 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03262132 0,09031865 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03262132 0,09021483 ! thymic T cell selection GO:0045061 12 6 0,000 0,03262132 0,09011126 ! protein lipoylation GO:0009249 10 6 0,000 0,03262132 0,09000792 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03262132 0,08990482 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03262132 0,08980195 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03262132 0,08969932 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03262132 0,08959692 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03262132 0,08949476 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,03262132 0,08939283 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03262132 0,08929113 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03262132 0,08918966 ! hyperosmotic response GO:0006972 9 6 0,000 0,03262132 0,08908843 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03262132 0,08898742 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03262132 0,08888664 ! urea metabolic process GO:0019627 7 6 0,000 0,03262132 0,08878609 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03262132 0,08868577 ! neutrophil activation GO:0042119 8 6 0,000 0,03262132 0,08858567 ! regulation of appetite GO:0032098 9 6 0,000 0,03262132 0,0884858 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03262132 0,08838615 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03262132 0,08828673 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03262132 0,08818753 ! nucleoside salvage GO:0043174 9 6 0,000 0,03262132 0,08808856 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03262132 0,0879898 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03262132 0,08789127 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03262132 0,08779296 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03262132 0,08769487 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03262132 0,08759699 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03262132 0,08749934 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03262132 0,0874019 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03262132 0,08730468 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03262132 0,08720767 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03262132 0,08711088 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03262132 0,08701431 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03262132 0,08691795 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03262132 0,0868218 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03262132 0,08672586 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03262132 0,08663014 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03262132 0,08653462 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03262132 0,08643932 ! response to UV-C GO:0010225 11 6 0,000 0,03262132 0,08634423 ! astrocyte development GO:0014002 15 6 0,000 0,03262132 0,08624935 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03262132 0,08615467 ! interaction with symbiont GO:0051702 13 6 0,000 0,03262132 0,0860602 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03262132 0,08596594 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03262132 0,08587189 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03262132 0,08577804 ! response to copper ion GO:0046688 10 6 0,000 0,03262132 0,08568439 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03262132 0,08559095 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03262132 0,08549772 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03262132 0,08540468 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03262132 0,08531185 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03262132 0,08521922 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03262132 0,08512679 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03262132 0,08503457 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03262132 0,08494254 ! hair follicle maturation GO:0048820 7 6 0,000 0,03262132 0,08485071 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03262132 0,08475908 ! Schwann cell development GO:0014044 15 6 0,000 0,03262132 0,08466764 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03262132 0,08457641 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03262132 0,08448537 ! subpallium development GO:0021544 10 6 0,000 0,03262132 0,08439452 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03262132 0,08430387 ! histone ubiquitination GO:0016574 8 6 0,000 0,03262132 0,08421342 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03262132 0,08412316 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03262132 0,08403309 ! G2 phase GO:0051319 16 6 0,000 0,03262132 0,08394321 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03262132 0,08385353 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03262132 0,08376404 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03262132 0,08367474 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03262132 0,08358563 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03262132 0,08349671 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03262132 0,08340798 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03262132 0,08331943 ! receptor internalization GO:0031623 10 6 0,000 0,03262132 0,08323108 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03262132 0,08314291 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03262132 0,08305493 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03262132 0,08296713 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03262132 0,08287952 ! protein deubiquitination GO:0016579 14 6 0,000 0,03262132 0,08279209 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03262132 0,08270485 ! protein destabilization GO:0031648 9 6 0,000 0,03262132 0,08261779 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03262132 0,08253092 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03262132 0,08244423 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03262132 0,08235772 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03262132 0,08227139 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03262132 0,08218524 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03262132 0,08209927 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03262132 0,08201348 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03262132 0,08192788 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03262132 0,08184245 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03262132 0,08175719 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03262132 0,08167212 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03262132 0,08158722 ! catecholamine transport GO:0051937 9 6 0,000 0,03262132 0,0815025 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03262132 0,08141795 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03262132 0,08133358 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03262132 0,08124938 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03262132 0,08116536 ! maternal placenta development GO:0001893 12 6 0,000 0,03262132 0,08108151 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03262132 0,08099784 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03262132 0,08091433 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03262132 0,080831 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03262132 0,08074784 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03262132 0,08066486 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03262132 0,08058204 ! synapse organization GO:0050808 85 52 1,000 0,03344981 0,08254384 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03463814 0,0853887 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03584272 0,08826773 ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,03584272 0,08817748 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,03706332 0,09108719 GO:0010952|positive regulation of peptidase activity, ! gastrulation GO:0007369 112 55 1,000 0,03706332 0,09099424 ! heart morphogenesis GO:0003007 97 55 1,000 0,03706332 0,09090149 ! tRNA transcription GO:0009304 14 7 0,000 0,03795442 0,09299219 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03795442 0,09289759 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03795442 0,09280319 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03795442 0,09270897 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03795442 0,09261494 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03795442 0,09252111 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03795442 0,09242746 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03795442 0,09233401 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03795442 0,09224074 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03795442 0,09214766 ! prostate gland development GO:0030850 13 7 0,000 0,03795442 0,09205477 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03795442 0,09196207 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03795442 0,09186955 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03795442 0,09177722 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03795442 0,09168507 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03795442 0,09159311 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03795442 0,09150134 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03795442 0,09140974 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03795442 0,09131833 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03795442 0,09122711 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03795442 0,09113606 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03795442 0,0910452 ! glycolipid transport GO:0046836 10 7 0,000 0,03795442 0,09095452 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03795442 0,09086401 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03795442 0,09077369 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03795442 0,09068355 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03795442 0,09059359 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03795442 0,0905038 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03795442 0,09041419 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03795442 0,09032476 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03795442 0,09023551 ! pericardium development GO:0060039 14 7 0,000 0,03795442 0,09014643 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03795442 0,09005753 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03795442 0,0899688 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03795442 0,08988025 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03795442 0,08979187 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03795442 0,08970367 ! lipoprotein transport GO:0042953 14 7 0,000 0,03795442 0,08961564 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03795442 0,08952778 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03795442 0,08944009 ! rhythmic behavior GO:0007622 15 7 0,000 0,03795442 0,08935258 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03795442 0,08926523 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03795442 0,08917806 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03795442 0,08909106 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03795442 0,08900422 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03795442 0,08891756 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03795442 0,08883106 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03795442 0,08874474 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03795442 0,08865858 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03795442 0,08857258 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03795442 0,08848676 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03795442 0,0884011 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03795442 0,0883156 ! spinal cord patterning GO:0021511 13 7 0,000 0,03795442 0,08823027 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03795442 0,08814511 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03795442 0,08806011 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03795442 0,08797527 ! adrenal gland development GO:0030325 17 7 0,000 0,03795442 0,0878906 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03795442 0,08780609 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03795442 0,08772174 ! ovulation GO:0030728 9 7 0,000 0,03795442 0,08763756 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03795442 0,08755353 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03795442 0,08746967 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03795442 0,08738597 ! microtubule nucleation GO:0007020 20 7 0,000 0,03795442 0,08730242 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03795442 0,08721904 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03795442 0,08713582 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03795442 0,08705275 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03795442 0,08696984 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03795442 0,08688709 ! galactose metabolic process GO:0006012 13 7 0,000 0,03795442 0,0868045 ! vesicle fusion GO:0006906 17 7 0,000 0,03795442 0,08672206 ! response to dietary excess GO:0002021 8 7 0,000 0,03795442 0,08663979 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03795442 0,08655766 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,03795442 0,0864757 ! purine salvage GO:0043101 10 7 0,000 0,03795442 0,08639388 ! nucleoside transport GO:0015858 8 7 0,000 0,03795442 0,08631223 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03795442 0,08623072 ! parturition GO:0007567 14 7 0,000 0,03795442 0,08614937 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03795442 0,08606818 ! rRNA modification GO:0000154 14 7 0,000 0,03795442 0,08598713 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03795442 0,08590624 ! spindle checkpoint GO:0031577 15 7 0,000 0,03795442 0,0858255 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03795442 0,08574491 ! macrophage differentiation GO:0030225 11 7 0,000 0,03795442 0,08566448 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03795442 0,08558419 ! centrosome duplication GO:0051298 13 7 0,000 0,03795442 0,08550406 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03795442 0,08542407 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03795442 0,08534424 ! eating behavior GO:0042755 7 7 0,000 0,03795442 0,08526455 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03795442 0,08518501 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03795442 0,08510562 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03795442 0,08502638 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03795442 0,08494729 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03795442 0,08486834 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03795442 0,08478954 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03795442 0,08471089 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03795442 0,08463238 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03795442 0,08455401 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03795442 0,08447579 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03795442 0,08439772 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03795442 0,08431979 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03795442 0,08424201 ! regulation of meiosis GO:0040020 12 7 0,000 0,03795442 0,08416436 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03795442 0,08408686 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03795442 0,08400951 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03795442 0,08393229 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03795442 0,08385522 ! transcription termination GO:0006353 13 7 0,000 0,03795442 0,08377829 ! response to tumor cell GO:0002347 13 7 0,000 0,03795442 0,0837015 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03795442 0,08362485 ! anaphase GO:0051322 17 7 0,000 0,03795442 0,08354834 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03795442 0,08347197 ! axonal fasciculation GO:0007413 18 7 0,000 0,03795442 0,08339574 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03795442 0,08331965 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03795442 0,0832437 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03795442 0,08316788 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03795442 0,08309221 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03795442 0,08301667 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03795442 0,08294127 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03795442 0,082866 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03795442 0,08279087 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03795442 0,08271588 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03795442 0,08264103 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03795442 0,08256631 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03795442 0,08249172 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03795442 0,08241727 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03795442 0,08234295 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03795442 0,08226877 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03795442 0,08219472 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03795442 0,0821208 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03795442 0,08204702 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03795442 0,08197337 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03795442 0,08189985 ! adult feeding behavior GO:0008343 9 7 0,000 0,03795442 0,08182646 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03795442 0,08175321 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03795442 0,08168008 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03795442 0,08160709 ! muscle adaptation GO:0043500 14 7 0,000 0,03795442 0,08153423 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03795442 0,08146149 ! retina homeostasis GO:0001895 12 7 0,000 0,03795442 0,08138889 ! protein prenylation GO:0018342 18 7 0,000 0,03795442 0,08131642 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03795442 0,08124407 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03795442 0,08117185 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03795442 0,08109976 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03829975 0,08176505 ! muscle fiber development GO:0048747 112 57 1,000 0,0395518 0,08436314 ! lipid modification GO:0030258 97 57 1,000 0,0395518 0,08428842 ! maintenance of location GO:0051235 118 57 1,000 0,0395518 0,08421382 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04210189 0,08956423 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04210189 0,08948511 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04325829 0,09186183 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04325829 0,09178082 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04325829 0,09169995 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04325829 0,09161923 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04325829 0,09153865 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04325829 0,09145822 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04325829 0,09137792 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04325829 0,09129776 ! meiotic prophase I GO:0007128 13 8 0,000 0,04325829 0,09121775 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04325829 0,09113787 ! oligopeptide transport GO:0006857 15 8 0,000 0,04325829 0,09105814 ! UTP metabolic process GO:0046051 8 8 0,000 0,04325829 0,09097854 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04325829 0,09089908 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04325829 0,09081976 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04325829 0,09074058 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04325829 0,09066154 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04325829 0,09058264 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04325829 0,09050387 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04325829 0,09042524 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04325829 0,09034674 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04325829 0,09026839 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04325829 0,09019016 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04325829 0,09011208 ! reflex GO:0060004 16 8 0,000 0,04325829 0,09003413 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04325829 0,08995631 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04325829 0,08987863 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04325829 0,08980108 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04325829 0,08972366 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04325829 0,08964638 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04325829 0,08956923 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04325829 0,08949222 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04325829 0,08941533 ! histidine metabolic process GO:0006547 16 8 0,000 0,04325829 0,08933858 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04325829 0,08926196 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04325829 0,08918547 ! glycine catabolic process GO:0006546 13 8 0,000 0,04325829 0,08910912 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04325829 0,08903289 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04325829 0,08895679 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04325829 0,08888083 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04325829 0,08880499 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04325829 0,08872928 ! macrophage activation GO:0042116 12 8 0,000 0,04325829 0,0886537 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04325829 0,08857825 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04325829 0,08850293 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04325829 0,08842774 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04325829 0,08835267 ! osteoblast development GO:0002076 16 8 0,000 0,04325829 0,08827773 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04325829 0,08820292 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04325829 0,08812824 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04325829 0,08805368 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04325829 0,08797925 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04325829 0,08790494 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04325829 0,08783076 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04325829 0,0877567 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04325829 0,08768277 ! intermediate filament organization GO:0045109 12 8 0,000 0,04325829 0,08760896 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04325829 0,08753528 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04325829 0,08746172 ! cellular extravasation GO:0045123 12 8 0,000 0,04325829 0,08738829 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04325829 0,08731497 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04325829 0,08724178 ! response to antibiotic GO:0046677 11 8 0,000 0,04325829 0,08716872 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04325829 0,08709577 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04325829 0,08702295 ! DNA topological change GO:0006265 12 8 0,000 0,04325829 0,08695025 ! response to tropane GO:0014073 15 8 0,000 0,04325829 0,08687767 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04325829 0,08680521 ! melanosome transport GO:0032402 13 8 0,000 0,04325829 0,08673287 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04325829 0,08666066 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04325829 0,08658856 ! mast cell activation GO:0045576 14 8 0,000 0,04325829 0,08651658 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04325829 0,08644472 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04325829 0,08637299 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04325829 0,08630137 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04325829 0,08622987 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04325829 0,08615848 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04325829 0,08608722 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04325829 0,08601607 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04325829 0,08594504 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04325829 0,08587413 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04325829 0,08580334 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04325829 0,08573266 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04325829 0,0856621 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04325829 0,08559165 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04325829 0,08552132 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04325829 0,08545111 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04325829 0,08538101 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04325829 0,08531102 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04325829 0,08524115 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04325829 0,0851714 ! hormone catabolic process GO:0042447 17 8 0,000 0,04325829 0,08510176 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04325829 0,08503223 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04325829 0,08496282 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04325829 0,08489351 ! ATP catabolic process GO:0006200 11 8 0,000 0,04325829 0,08482433 ! blastocyst growth GO:0001832 19 8 0,000 0,04325829 0,08475525 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04325829 0,08468629 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04325829 0,08461744 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04325829 0,0845487 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04325829 0,08448007 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04325829 0,08441156 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04325829 0,08434315 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04325829 0,08427486 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04325829 0,08420667 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04325829 0,0841386 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04325829 0,08407064 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04325829 0,08400278 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04325829 0,08393504 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04325829 0,0838674 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04325829 0,08379988 ! viral reproductive process GO:0022415 126 62 1,000 0,046039 0,08911491 ! gonad development GO:0008406 98 62 1,000 0,046039 0,08904327 ! axon extension GO:0048675 15 9 0,000 0,0485331 0,09379167 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0485331 0,0937164 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0485331 0,09364124 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0485331 0,09356621 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0485331 0,0934913 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0485331 0,0934165 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0485331 0,09334183 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0485331 0,09326728 ! phosphate transport GO:0006817 19 9 0,000 0,0485331 0,09319284 ! reproductive behavior GO:0019098 19 9 0,000 0,0485331 0,09311853 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0485331 0,09304433 ! CTP metabolic process GO:0046036 9 9 0,000 0,0485331 0,09297025 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0485331 0,09289629 ! GTP metabolic process GO:0046039 9 9 0,000 0,0485331 0,09282244 ! RNA methylation GO:0001510 15 9 0,000 0,0485331 0,09274871 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0485331 0,0926751 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0485331 0,09260161 ! artery development GO:0060840 24 9 0,000 0,0485331 0,09252823 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0485331 0,09245497 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0485331 0,09238183 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0485331 0,0923088 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0485331 0,09223589 ! chemosensory behavior GO:0007635 20 9 0,000 0,0485331 0,09216309 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0485331 0,0920904 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0485331 0,09201783 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0485331 0,09194538 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0485331 0,09187304 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0485331 0,09180081 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0485331 0,0917287 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0485331 0,0916567 ! protein targeting to ER GO:0045047 22 9 0,000 0,0485331 0,09158481 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0485331 0,09151303 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0485331 0,09144137 ! endosome organization GO:0007032 17 9 0,000 0,0485331 0,09136982 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0485331 0,09129838 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0485331 0,09122706 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0485331 0,09115584 ! mannose metabolic process GO:0006013 13 9 0,000 0,0485331 0,09108474 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0485331 0,09101374 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0485331 0,09094286 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0485331 0,09087209 ! receptor clustering GO:0043113 18 9 0,000 0,0485331 0,09080142 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0485331 0,09073087 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0485331 0,09066043 ! ruffle organization GO:0031529 15 9 0,000 0,0485331 0,09059009 ! retinol metabolic process GO:0042572 18 9 0,000 0,0485331 0,09051987 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0485331 0,09044975 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0485331 0,09037975 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0485331 0,09030985 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0485331 0,09024006 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,0485331 0,09017037 ! segment specification GO:0007379 13 9 0,000 0,0485331 0,0901008 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0485331 0,09003133 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0485331 0,08996197 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0485331 0,08989271 ! response to amine stimulus GO:0014075 13 9 0,000 0,0485331 0,08982356 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0485331 0,08975452 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0485331 0,08968558 ! erythrocyte development GO:0048821 15 9 0,000 0,0485331 0,08961675 ! gas homeostasis GO:0033483 16 9 0,000 0,0485331 0,08954803 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0485331 0,08947941 ! postreplication repair GO:0006301 22 9 0,000 0,0485331 0,0894109 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0485331 0,08934249 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0485331 0,08927418 ! icosanoid secretion GO:0032309 15 9 0,000 0,0485331 0,08920598 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0485331 0,08913789 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0485331 0,08906989 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0485331 0,08900201 ! regulation of cell division GO:0051302 15 9 0,000 0,0485331 0,08893422 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0485331 0,08886654 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0485331 0,08879896 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0485331 0,08873148 ! sterol catabolic process GO:0016127 11 9 0,000 0,0485331 0,08866411 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0485331 0,08859684 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0485331 0,08852967 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0485331 0,0884626 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0485331 0,08839563 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0485331 0,08832877 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0485331 0,088262 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0485331 0,08819534 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0485331 0,08812878 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0485331 0,08806232 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0485331 0,08799595 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0485331 0,08792969 ! pigment granule transport GO:0051904 17 9 0,000 0,0485331 0,08786353 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0485331 0,08779747 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0485331 0,0877315 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0485331 0,08766564 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0485331 0,08759987 ! mitochondrion localization GO:0051646 15 9 0,000 0,0485331 0,08753421 ! single fertilization GO:0007338 75 64 1,000 0,04873604 0,0878344 ! germ cell development GO:0007281 118 65 1,000 0,05010567 0,09023521 ! cell projection assembly GO:0030031 120 66 1,000 0,0514891 0,09265728 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,05288615 0,09510021 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,05288615 0,09502919 ! adaptive immune response GO:0002250 119 67 1,000 0,05288615 0,09495827 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,053779 0,09648938 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,053779 0,09641748 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,053779 0,09634569 ! synapsis GO:0007129 13 10 0,000 0,053779 0,096274 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,053779 0,09620243 ! N-glycan processing GO:0006491 20 10 0,000 0,053779 0,09613095 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,053779 0,09605959 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,053779 0,09598833 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,053779 0,09591717 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,053779 0,09584612 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,053779 0,09577518 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,053779 0,09570434 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,053779 0,0956336 ! androgen metabolic process GO:0008209 17 10 0,000 0,053779 0,09556297 ! phospholipid efflux GO:0033700 16 10 0,000 0,053779 0,09549244 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,053779 0,09542202 ! pathogenesis GO:0009405 13 10 0,000 0,053779 0,0953517 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,053779 0,09528149 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,053779 0,09521138 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,053779 0,09514137 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,053779 0,09507146 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,053779 0,09500166 ! endoderm development GO:0007492 16 10 0,000 0,053779 0,09493196 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,053779 0,09486236 ! arginine catabolic process GO:0006527 13 10 0,000 0,053779 0,09479287 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,053779 0,09472347 ! proline metabolic process GO:0006560 13 10 0,000 0,053779 0,09465418 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,053779 0,09458499 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,053779 0,0945159 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,053779 0,09444691 ! V(D)J recombination GO:0033151 28 10 0,000 0,053779 0,09437802 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,053779 0,09430923 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,053779 0,09424054 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,053779 0,09417195 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,053779 0,09410346 ! multicellular organism growth GO:0035264 18 10 0,000 0,053779 0,09403507 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,053779 0,09396678 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,053779 0,09389859 ! epithelial cell development GO:0002064 20 10 0,000 0,053779 0,0938305 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,053779 0,09376251 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,053779 0,09369461 ! macroautophagy GO:0016236 17 10 0,000 0,053779 0,09362682 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,053779 0,09355912 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,053779 0,09349152 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,053779 0,09342402 ! copper ion homeostasis GO:0055070 13 10 0,000 0,053779 0,09335661 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,053779 0,0932893 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,053779 0,09322209 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,053779 0,09315498 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,053779 0,09308796 ! blastoderm segmentation GO:0007350 18 10 0,000 0,053779 0,09302104 ! response to dsRNA GO:0043331 20 10 0,000 0,053779 0,09295421 ! DNA ligation GO:0006266 19 10 0,000 0,053779 0,09288748 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,053779 0,09282085 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,053779 0,09275431 ! melanosome localization GO:0032400 16 10 0,000 0,053779 0,09268787 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,053779 0,09262152 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,053779 0,09255527 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,053779 0,09248911 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,053779 0,09242304 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,053779 0,09235708 ! mRNA cleavage GO:0006379 17 10 0,000 0,053779 0,0922912 ! protein sumoylation GO:0016925 15 10 0,000 0,053779 0,09222542 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,053779 0,09215973 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,053779 0,09209414 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,053779 0,09202864 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,053779 0,09196323 ! salivary gland development GO:0007431 27 10 0,000 0,053779 0,09189791 ! prophase GO:0051324 15 10 0,000 0,053779 0,09183269 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,053779 0,09176756 ! apical protein localization GO:0045176 15 10 0,000 0,053779 0,09170252 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,053779 0,09163758 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,053779 0,09157273 ! midbrain development GO:0030901 13 10 0,000 0,053779 0,09150797 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,053779 0,0914433 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,053779 0,09137872 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,053779 0,09131423 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,053779 0,09124983 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,053779 0,09118553 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,053779 0,09112131 ! detection of calcium ion GO:0005513 23 10 0,000 0,053779 0,09105719 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,053779 0,09099315 ! blastocyst formation GO:0001825 17 10 0,000 0,053779 0,09092921 ! cerebellar cortex development GO:0021695 15 10 0,000 0,053779 0,09086535 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,053779 0,09080159 ! activation of innate immune response GO:0002218 12 10 0,000 0,053779 0,09073791 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,053779 0,09067433 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,053779 0,09061083 ! establishment of cell polarity GO:0030010 16 10 0,000 0,053779 0,09054742 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,053779 0,0904841 ! amino acid transport GO:0006865 125 68 1,000 0,05429663 0,09129119 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,05429663 0,09122744 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,05429663 0,09116378 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,05572035 0,09348895 ! reproductive structure development GO:0048608 113 71 1,000 0,05860676 0,09826331 ! humoral immune response GO:0006959 109 71 1,000 0,05860676 0,09819489 ! B cell activation GO:0042113 160 71 1,000 0,05860676 0,09812655 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05899614 0,09870982 ! respiratory burst GO:0045730 17 11 0,000 0,05899614 0,09864122 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05899614 0,09857272 ! neuron fate specification GO:0048665 17 11 0,000 0,05899614 0,09850432 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05899614 0,09843601 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05899614 0,09836779 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05899614 0,09829967 ! thyroid gland development GO:0030878 26 11 0,000 0,05899614 0,09823164 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05899614 0,09816371 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05899614 0,09809587 ! response to pain GO:0048265 24 11 0,000 0,05899614 0,09802812 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05899614 0,09796047 ! T cell proliferation GO:0042098 26 11 0,000 0,05899614 0,09789291 ! bone resorption GO:0045453 16 11 0,000 0,05899614 0,09782545 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05899614 0,09775807 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05899614 0,09769079 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05899614 0,0976236 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05899614 0,09755651 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05899614 0,09748951 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05899614 0,0974226 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05899614 0,09735578 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05899614 0,09728905 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05899614 0,09722241 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05899614 0,09715587 ! lipid digestion GO:0044241 18 11 0,000 0,05899614 0,09708941 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05899614 0,09702305 ! UV protection GO:0009650 19 11 0,000 0,05899614 0,09695678 ! adult heart development GO:0007512 14 11 0,000 0,05899614 0,09689059 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05899614 0,0968245 ! temperature homeostasis GO:0001659 17 11 0,000 0,05899614 0,0967585 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05899614 0,09669259 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05899614 0,09662677 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05899614 0,09656104 ! regulation of organ growth GO:0046620 13 11 0,000 0,05899614 0,09649539 ! pigment granule localization GO:0051875 20 11 0,000 0,05899614 0,09642984 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05899614 0,09636437 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05899614 0,096299 ! embryonic axis specification GO:0000578 18 11 0,000 0,05899614 0,09623371 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05899614 0,09616851 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05899614 0,0961034 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05899614 0,09603838 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05899614 0,09597344 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05899614 0,0959086 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05899614 0,09584384 ! zymogen activation GO:0031638 15 11 0,000 0,05899614 0,09577916 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05899614 0,09571458 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05899614 0,09565008 ! nucleosome positioning GO:0016584 15 11 0,000 0,05899614 0,09558567 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05899614 0,09552135 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05899614 0,09545711 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05899614 0,09539296 ! acid secretion GO:0046717 18 11 0,000 0,05899614 0,09532889 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05899614 0,09526491 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05899614 0,09520102 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05899614 0,09513721 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05899614 0,09507349 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05899614 0,09500985 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,05899614 0,0949463 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05899614 0,09488284 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05899614 0,09481945 ! germ cell migration GO:0008354 25 11 0,000 0,05899614 0,09475616 ! embryonic gut development GO:0048566 15 11 0,000 0,05899614 0,09469294 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05899614 0,09462981 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05899614 0,09456677 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05899614 0,09450381 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05899614 0,09444093 ! defense response to fungus GO:0050832 13 11 0,000 0,05899614 0,09437814 ! developmental induction GO:0031128 19 11 0,000 0,05899614 0,09431543 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05899614 0,0942528 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05899614 0,09419026 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05899614 0,0941278 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05899614 0,09406542 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05899614 0,09400313 ! nucleus localization GO:0051647 19 11 0,000 0,05899614 0,09394091 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05899614 0,09387878 ! acute inflammatory response GO:0002526 113 72 1,000 0,06006908 0,09552293 ! regulation of caspase activity GO:0043281 122 72 1,000 0,06006908 0,09545984 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06006908 0,09539683 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06006908 0,0953339 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,06006908 0,09527106 ! regulation of blood pressure GO:0008217 125 73 1,000 0,0615439 0,09754586 ! axon guidance GO:0007411 139 73 1,000 0,0615439 0,09748165 ! fertilization GO:0009566 90 73 1,000 0,0615439 0,09741751 ! meiosis GO:0007126 121 74 1,000 0,06303104 0,09970591 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,06303104 0,0996404 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,06303104 0,09957498 ! organelle localization GO:0051640 136 74 1,000 0,06303104 0,09950964 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0641847 0,10126451 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0641847 0,10119816 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0641847 0,10113188 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0641847 0,1010657 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0641847 0,1009996 ! cartilage condensation GO:0001502 20 12 0,000 0,0641847 0,10093359 ! mating GO:0007618 17 12 0,000 0,0641847 0,10086766 ! protein complex disassembly GO:0043241 27 12 0,000 0,0641847 0,10080182 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0641847 0,10073606 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0641847 0,10067039 ! hippocampus development GO:0021766 26 12 0,000 0,0641847 0,10060481 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0641847 0,10053931 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0641847 0,1004739 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0641847 0,10040857 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0641847 0,10034333 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0641847 0,10027817 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0641847 0,1002131 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0641847 0,10014811 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0641847 0,1000832 ! drug transport GO:0015893 16 12 0,000 0,0641847 0,10001838 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0641847 0,09995365 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0641847 0,09988899 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0641847 0,09982442 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0641847 0,09975994 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0641847 0,09969554 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0641847 0,09963122 ! forebrain cell migration GO:0021885 21 12 0,000 0,0641847 0,09956698 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0641847 0,09950283 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0641847 0,09943875 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0641847 0,09937477 ! entry into host cell GO:0030260 32 12 0,000 0,0641847 0,09931086 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,0641847 0,09924703 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0641847 0,09918329 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0641847 0,09911963 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0641847 0,09905605 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0641847 0,09899255 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0641847 0,09892914 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0641847 0,0988658 ! protein homotetramerization GO:0051289 21 12 0,000 0,0641847 0,09880255 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0641847 0,09873938 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0641847 0,09867628 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0641847 0,09861327 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0641847 0,09855034 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0641847 0,09848749 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0641847 0,09842472 ! fucose catabolic process GO:0019317 22 12 0,000 0,0641847 0,09836203 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0641847 0,09829942 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0641847 0,09823689 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0641847 0,09817443 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0641847 0,09811206 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0641847 0,09804977 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0641847 0,09798755 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0641847 0,09792542 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0641847 0,09786336 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0641847 0,09780138 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0641847 0,09773948 ! response to cold GO:0009409 17 12 0,000 0,0641847 0,09767766 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0641847 0,09761592 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0641847 0,09755425 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,06453033 0,09801766 ! meiotic cell cycle GO:0051321 122 75 1,000 0,06453033 0,09795582 ! rhythmic process GO:0048511 128 75 1,000 0,06453033 0,09789405 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,06453033 0,09783237 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,06604158 0,10006048 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,06604158 0,09999751 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,06604158 0,09993462 ! regulation of catabolic process GO:0009894 161 76 1,000 0,06604158 0,0998718 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,06756462 0,10211085 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,06756462 0,10204675 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06756462 0,10198273 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,06909928 0,10423377 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,06909928 0,10416846 ! protein oligomerization GO:0051259 139 78 1,000 0,06909928 0,10410323 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06934482 0,10440778 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06934482 0,10434248 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06934482 0,10427727 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06934482 0,10421213 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06934482 0,10414708 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06934482 0,10408211 ! lipid localization GO:0010876 28 13 0,000 0,06934482 0,10401722 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06934482 0,10395242 ! organelle fusion GO:0048284 32 13 0,000 0,06934482 0,10388769 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06934482 0,10382304 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06934482 0,10375848 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06934482 0,10369399 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06934482 0,10362958 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06934482 0,10356526 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06934482 0,10350101 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06934482 0,10343684 ! methionine metabolic process GO:0006555 27 13 0,000 0,06934482 0,10337276 ! plasma membrane organization GO:0007009 24 13 0,000 0,06934482 0,10330875 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06934482 0,10324482 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06934482 0,10318097 ! Golgi organization GO:0007030 24 13 0,000 0,06934482 0,1031172 ! response to X-ray GO:0010165 25 13 0,000 0,06934482 0,10305351 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06934482 0,10298989 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06934482 0,10292636 ! exocrine system development GO:0035272 32 13 0,000 0,06934482 0,1028629 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06934482 0,10279952 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06934482 0,10273622 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06934482 0,102673 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06934482 0,10260986 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06934482 0,10254679 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06934482 0,1024838 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06934482 0,10242089 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06934482 0,10235805 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06934482 0,1022953 ! ribosome assembly GO:0042255 17 13 0,000 0,06934482 0,10223262 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06934482 0,10217001 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06934482 0,10210748 ! chromatin silencing GO:0006342 26 13 0,000 0,06934482 0,10204503 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06934482 0,10198266 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06934482 0,10192036 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06934482 0,10185814 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06934482 0,10179599 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06934482 0,10173392 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06934482 0,10167192 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06934482 0,10161 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06934482 0,10154816 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06934482 0,10148639 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06934482 0,1014247 ! embryonic placenta development GO:0001892 23 13 0,000 0,06934482 0,10136308 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06934482 0,10130153 ! insulin secretion GO:0030073 23 13 0,000 0,06934482 0,10124007 ! actin filament polymerization GO:0030041 24 13 0,000 0,06934482 0,10117867 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06934482 0,10111735 ! acrosome reaction GO:0007340 18 13 0,000 0,06934482 0,1010561 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,07064538 0,10288909 ! response to metal ion GO:0010038 140 80 1,000 0,07220275 0,10509366 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,07220275 0,10503012 ! rRNA transcription GO:0009303 25 14 0,000 0,07447665 0,1082724 ! lactation GO:0007595 26 14 0,000 0,07447665 0,10820702 ! reproductive cellular process GO:0048610 20 14 0,000 0,07447665 0,10814172 ! tRNA modification GO:0006400 20 14 0,000 0,07447665 0,10807649 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07447665 0,10801135 ! regulation of S phase GO:0033261 23 14 0,000 0,07447665 0,10794628 ! water transport GO:0006833 21 14 0,000 0,07447665 0,10788129 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07447665 0,10781638 ! non-recombinational repair GO:0000726 25 14 0,000 0,07447665 0,10775155 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07447665 0,10768679 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07447665 0,10762212 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07447665 0,10755752 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07447665 0,107493 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07447665 0,10742855 ! palate development GO:0060021 31 14 0,000 0,07447665 0,10736418 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07447665 0,10729989 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07447665 0,10723568 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07447665 0,10717154 ! arginine metabolic process GO:0006525 17 14 0,000 0,07447665 0,10710749 ! organic alcohol transport GO:0015850 29 14 0,000 0,07447665 0,1070435 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07447665 0,1069796 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07447665 0,10691577 ! embryo implantation GO:0007566 30 14 0,000 0,07447665 0,10685201 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07447665 0,10678833 ! L-amino acid transport GO:0015807 30 14 0,000 0,07447665 0,10672473 ! bone mineralization GO:0030282 17 14 0,000 0,07447665 0,1066612 ! stem cell development GO:0048864 43 14 0,000 0,07447665 0,10659775 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07447665 0,10653438 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07447665 0,10647108 ! cerebellum development GO:0021549 21 14 0,000 0,07447665 0,10640785 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07447665 0,1063447 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07447665 0,10628163 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07447665 0,10621863 ! cofactor transport GO:0051181 26 14 0,000 0,07447665 0,1061557 ! NADP metabolic process GO:0006739 24 14 0,000 0,07447665 0,10609285 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07447665 0,10603007 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07447665 0,10596737 ! intestinal absorption GO:0050892 25 14 0,000 0,07447665 0,10590474 ! oxygen transport GO:0015671 21 14 0,000 0,07447665 0,10584219 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07447665 0,10577971 ! male genitalia development GO:0030539 24 14 0,000 0,07447665 0,1057173 ! regulation of axon extension GO:0030516 37 14 0,000 0,07447665 0,10565497 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07535063 0,10683184 ! response to drug GO:0042493 143 82 1,000 0,07535063 0,10676892 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,07854159 0,11122488 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07958036 0,11262961 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,07958036 0,1125634 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07958036 0,11249726 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07958036 0,1124312 ! copper ion transport GO:0006825 20 15 0,000 0,07958036 0,11236522 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07958036 0,11229932 ! sulfate transport GO:0008272 23 15 0,000 0,07958036 0,11223349 ! response to cAMP GO:0051591 22 15 0,000 0,07958036 0,11216775 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07958036 0,11210207 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07958036 0,11203648 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07958036 0,11197096 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07958036 0,11190552 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07958036 0,11184015 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07958036 0,11177486 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07958036 0,11170965 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07958036 0,11164451 ! pituitary gland development GO:0021983 29 15 0,000 0,07958036 0,11157945 ! vesicle coating GO:0006901 33 15 0,000 0,07958036 0,11151447 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07958036 0,11144956 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07958036 0,11138472 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07958036 0,11131997 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07958036 0,11125528 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07958036 0,11119067 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07958036 0,11112614 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07958036 0,11106168 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07958036 0,1109973 ! histone deacetylation GO:0016575 20 15 0,000 0,07958036 0,11093299 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07958036 0,11086876 ! tissue regeneration GO:0042246 26 15 0,000 0,07958036 0,1108046 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07958036 0,11074051 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07958036 0,1106765 ! muscle maintenance GO:0046716 26 15 0,000 0,07958036 0,11061256 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07958036 0,1105487 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07958036 0,11048491 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07958036 0,11042119 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07958036 0,11035755 ! cell killing GO:0001906 29 15 0,000 0,07958036 0,11029398 ! detection of bacterium GO:0016045 18 15 0,000 0,07958036 0,11023048 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07958036 0,11016705 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07958036 0,1101037 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07958036 0,11004043 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07958036 0,10997722 ! peptide hormone processing GO:0016486 23 15 0,000 0,07958036 0,10991409 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,08015282 0,11064124 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,08015282 0,1105778 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,08177432 0,11275014 ! amine transport GO:0015837 155 86 1,000 0,08177432 0,11268557 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08340593 0,11486816 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,08340593 0,11480244 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08465609 0,11645658 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08465609 0,11639003 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08465609 0,11632356 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08465609 0,11625716 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08465609 0,11619084 ! bone remodeling GO:0046849 27 16 0,000 0,08465609 0,1161246 ! filopodium assembly GO:0046847 32 16 0,000 0,08465609 0,11605843 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08465609 0,11599234 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08465609 0,11592632 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08465609 0,11586038 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08465609 0,11579451 ! startle response GO:0001964 28 16 0,000 0,08465609 0,11572872 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08465609 0,115663 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08465609 0,11559736 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08465609 0,11553179 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08465609 0,1154663 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08465609 0,11540088 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08465609 0,11533553 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08465609 0,11527026 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08465609 0,11520506 ! response to osmotic stress GO:0006970 25 16 0,000 0,08465609 0,11513994 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08465609 0,11507489 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08465609 0,11500991 ! fructose metabolic process GO:0006000 25 16 0,000 0,08465609 0,11494501 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08465609 0,11488017 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08465609 0,11481542 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08465609 0,11475073 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08465609 0,11468612 ! axon cargo transport GO:0008088 43 16 0,000 0,08465609 0,11462158 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08465609 0,11455711 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08465609 0,11449272 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08465609 0,1144284 ! neuron recognition GO:0008038 35 16 0,000 0,08465609 0,11436415 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08465609 0,11429997 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08465609 0,11423587 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08465609 0,11417183 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08465609 0,11410787 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08465609 0,11404398 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08465609 0,11398016 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08465609 0,11391642 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08465609 0,11385274 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08465609 0,11378913 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08465609 0,1137256 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08465609 0,11366214 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,0883599 0,11856883 ! sex differentiation GO:0007548 145 90 1,000 0,0883599 0,11850274 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,089704 0,12023834 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,089704 0,12017139 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,089704 0,12010452 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,089704 0,12003772 ! endothelial cell migration GO:0043542 28 17 0,000 0,089704 0,11997099 ! inositol metabolic process GO:0006020 28 17 0,000 0,089704 0,11990434 ! gene silencing by RNA GO:0031047 36 17 0,000 0,089704 0,11983777 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,089704 0,11977126 ! glial cell development GO:0021782 27 17 0,000 0,089704 0,11970484 ! limbic system development GO:0021761 36 17 0,000 0,089704 0,11963848 ! adult walking behavior GO:0007628 33 17 0,000 0,089704 0,1195722 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,089704 0,11950599 ! heart looping GO:0001947 30 17 0,000 0,089704 0,11943985 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,089704 0,11937379 ! myoblast differentiation GO:0045445 45 17 0,000 0,089704 0,1193078 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,089704 0,11924189 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,089704 0,11917605 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,089704 0,11911027 ! glycine metabolic process GO:0006544 28 17 0,000 0,089704 0,11904458 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,089704 0,11897895 ! NAD metabolic process GO:0019674 29 17 0,000 0,089704 0,1189134 ! membrane budding GO:0006900 37 17 0,000 0,089704 0,11884792 ! DNA integration GO:0015074 29 17 0,000 0,089704 0,11878251 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,089704 0,11871717 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,089704 0,11865191 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,089704 0,11858671 ! genitalia development GO:0048806 30 17 0,000 0,089704 0,11852159 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,089704 0,11845654 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,089704 0,11839156 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,089704 0,11832665 ! steroid catabolic process GO:0006706 31 17 0,000 0,089704 0,11826182 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,089704 0,11819705 ! gas transport GO:0015669 25 17 0,000 0,089704 0,11813236 ! organic cation transport GO:0015695 31 17 0,000 0,089704 0,11806773 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,089704 0,11800318 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,089704 0,1179387 ! microspike assembly GO:0030035 36 17 0,000 0,089704 0,11787429 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,089704 0,11780994 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,089704 0,11774567 ! response to protein stimulus GO:0051789 149 91 1,000 0,09003041 0,11810969 ! vitamin metabolic process GO:0006766 139 92 1,000 0,09171025 0,12024788 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,09339928 0,12239579 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09472423 0,12406451 ! neuron maturation GO:0042551 42 18 0,000 0,09472423 0,12399701 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09472423 0,12392959 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09472423 0,12386223 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09472423 0,12379495 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09472423 0,12372775 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09472423 0,12366061 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09472423 0,12359355 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09472423 0,12352656 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09472423 0,12345965 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09472423 0,1233928 ! response to fungus GO:0009620 21 18 0,000 0,09472423 0,12332603 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09472423 0,12325933 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09472423 0,12319271 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09472423 0,12312615 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09472423 0,12305967 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09472423 0,12299326 ! vitamin transport GO:0051180 27 18 0,000 0,09472423 0,12292692 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09472423 0,12286065 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09472423 0,12279445 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09472423 0,12272833 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09472423 0,12266228 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09472423 0,12259629 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09472423 0,12253038 ! forebrain development GO:0030900 188 95 1,000 0,09680428 0,12515374 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,09680428 0,12508652 ! leukocyte differentiation GO:0002521 202 96 1,000 0,09851996 0,12723512 ! protein secretion GO:0009306 39 19 0,000 0,09971695 0,1287119 ! positive regulation of translation GO:0045727 30 19 0,000 0,09971695 0,12864289 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09971695 0,12857395 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09971695 0,12850508 ! skin development GO:0043588 36 19 0,000 0,09971695 0,12843629 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09971695 0,12836757 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09971695 0,12829892 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09971695 0,12823035 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09971695 0,12816185 ! cerebral cortex development GO:0021987 36 19 0,000 0,09971695 0,12809342 ! pigmentation during development GO:0048066 41 19 0,000 0,09971695 0,12802507 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09971695 0,12795679 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,09971695 0,12788858 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09971695 0,12782045 ! protein export from nucleus GO:0006611 36 19 0,000 0,09971695 0,12775239 ! heart process GO:0003015 30 19 0,000 0,09971695 0,1276844 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09971695 0,12761648 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09971695 0,12754864 ! visual learning GO:0008542 36 19 0,000 0,09971695 0,12748086 ! G1 phase GO:0051318 40 19 0,000 0,09971695 0,12741316 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09971695 0,12734553 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09971695 0,12727798 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09971695 0,12721049 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09971695 0,12714308 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09971695 0,12707573 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09971695 0,12700846 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09971695 0,12694126 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09971695 0,12687413 ! cilium assembly GO:0042384 37 19 0,000 0,09971695 0,12680707 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,1046823 0,13305103 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,1046823 0,13298079 ! positive regulation of ossification GO:0045778 47 20 0,000 0,1046823 0,13291061 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,1046823 0,13284051 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,1046823 0,13277048 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,1046823 0,13270053 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,1046823 0,13263065 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,1046823 0,13256085 ! retinoid metabolic process GO:0001523 32 20 0,000 0,1046823 0,13249111 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,1046823 0,13242145 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,1046823 0,13235187 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,1046823 0,13228236 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,1046823 0,13221292 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,1046823 0,13214355 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,1046823 0,13207426 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,1046823 0,13200504 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,1046823 0,13193589 ! stem cell differentiation GO:0048863 53 20 0,000 0,1046823 0,13186681 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,1046823 0,13179781 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,1046823 0,13172887 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,1046823 0,13166001 ! sensory perception of pain GO:0019233 30 20 0,000 0,1046823 0,13159123 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,1046823 0,13152251 ! diencephalon development GO:0021536 34 20 0,000 0,1046823 0,13145387 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,1046823 0,13138529 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,1046823 0,13131679 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,1046823 0,13124836 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,1046823 0,13118 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,1046823 0,13111172 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,1046823 0,1310435 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,1046823 0,13097535 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,1046823 0,13090728 ! actin filament-based movement GO:0030048 43 20 0,000 0,1046823 0,13083928 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,1046823 0,13077134 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,1046823 0,13070348 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,1046823 0,13063569 ! regulation of cell killing GO:0031341 42 21 0,000 0,10962042 0,13672718 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10962042 0,13665634 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10962042 0,13658557 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10962042 0,13651487 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10962042 0,13644425 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10962042 0,1363737 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10962042 0,13630322 ! axis specification GO:0009798 38 21 0,000 0,10962042 0,13623282 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10962042 0,13616249 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10962042 0,13609223 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10962042 0,13602204 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10962042 0,13595193 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10962042 0,13588188 ! cytolysis GO:0019835 24 21 0,000 0,10962042 0,13581191 ! vasodilation GO:0042311 39 21 0,000 0,10962042 0,13574201 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10962042 0,13567219 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10962042 0,13560243 ! DNA modification GO:0006304 34 21 0,000 0,10962042 0,13553275 ! collagen fibril organization GO:0030199 59 21 0,000 0,10962042 0,13546314 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10962042 0,1353936 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10962042 0,13532413 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10962042 0,13525474 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10962042 0,13518541 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10962042 0,13511616 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10962042 0,13504697 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10962042 0,13497786 ! collagen catabolic process GO:0030574 28 21 0,000 0,10962042 0,13490882 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10962042 0,13483984 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11453147 0,14080875 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11453147 0,14073684 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11453147 0,14066499 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11453147 0,14059323 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11453147 0,14052153 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11453147 0,14044991 ! keratinization GO:0031424 28 22 0,000 0,11453147 0,14037836 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11453147 0,14030689 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11453147 0,14023548 ! sensory perception of taste GO:0050909 28 22 0,000 0,11453147 0,14016415 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11453147 0,1400929 ! vacuolar transport GO:0007034 36 22 0,000 0,11453147 0,14002171 ! lysosome organization GO:0007040 41 22 0,000 0,11453147 0,1399506 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11453147 0,13987956 ! fucose metabolic process GO:0006004 39 22 0,000 0,11453147 0,13980859 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11453147 0,13973769 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11453147 0,13966687 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11453147 0,13959611 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,11453147 0,13952543 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11453147 0,13945482 ! sarcomere organization GO:0045214 30 22 0,000 0,11453147 0,13938428 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11453147 0,13931381 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11453147 0,13924342 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11453147 0,13917309 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11453147 0,13910284 ! protein stabilization GO:0050821 39 22 0,000 0,11453147 0,13903266 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1194156 0,14488852 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1194156 0,14481549 ! gluconeogenesis GO:0006094 33 23 0,000 0,1194156 0,14474254 ! viral genome replication GO:0019079 41 23 0,000 0,1194156 0,14466965 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1194156 0,14459685 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1194156 0,14452411 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1194156 0,14445145 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1194156 0,14437886 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1194156 0,14430634 ! visual behavior GO:0007632 42 23 0,000 0,1194156 0,1442339 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1194156 0,14416153 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1194156 0,14408923 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,1194156 0,14401701 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1194156 0,14394486 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1194156 0,14387278 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1194156 0,14380077 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1194156 0,14372883 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,1194156 0,14365697 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1194156 0,14358517 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1194156 0,14351345 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1194156 0,1434418 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1194156 0,14337023 ! fatty acid transport GO:0015908 44 23 0,000 0,1194156 0,14329872 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1194156 0,14322728 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1194156 0,14315592 ! cell-cell recognition GO:0009988 25 23 0,000 0,1194156 0,14308463 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1194156 0,14301341 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1194156 0,14294225 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,1194156 0,14287117 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1194156 0,14280017 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1194156 0,14272923 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,12427295 0,14846113 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12427295 0,14838745 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12427295 0,14831384 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12427295 0,14824031 ! vesicle docking GO:0048278 47 24 0,000 0,12427295 0,14816685 ! spinal cord development GO:0021510 47 24 0,000 0,12427295 0,14809347 ! vacuole organization GO:0007033 43 24 0,000 0,12427295 0,14802015 ! digestive system process GO:0022600 39 24 0,000 0,12427295 0,14794691 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12427295 0,14787374 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12427295 0,14780065 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12427295 0,14772762 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12427295 0,14765467 ! pallium development GO:0021543 49 24 0,000 0,12427295 0,14758179 ! pentose metabolic process GO:0019321 35 24 0,000 0,12427295 0,14750898 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12427295 0,14743625 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12427295 0,14736358 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12427295 0,14729099 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12427295 0,14721847 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12427295 0,14714602 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12427295 0,14707364 ! regulation of amine transport GO:0051952 40 24 0,000 0,12427295 0,14700133 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12910366 0,1526405 ! phototransduction GO:0007602 33 25 0,000 0,12910366 0,15256553 ! sperm motility GO:0030317 31 25 0,000 0,12910366 0,15249063 ! receptor metabolic process GO:0043112 46 25 0,000 0,12910366 0,1524158 ! response to starvation GO:0042594 42 25 0,000 0,12910366 0,15234105 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12910366 0,15226638 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,12910366 0,15219177 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12910366 0,15211724 ! negative regulation of cell development GO:0010721 73 25 0,000 0,12910366 0,15204278 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12910366 0,1519684 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12910366 0,15189409 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12910366 0,15181985 ! immunoglobulin production GO:0002377 55 25 0,000 0,12910366 0,15174568 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12910366 0,15167159 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12910366 0,15159756 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,12910366 0,15152361 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12910366 0,15144974 ! telomere organization GO:0032200 43 25 0,000 0,12910366 0,15137593 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12910366 0,1513022 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12910366 0,15122853 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13390789 0,15677975 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13390789 0,15670349 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13390789 0,15662731 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13390789 0,1565512 ! initiation of viral infection GO:0019059 57 26 0,000 0,13390789 0,15647517 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13390789 0,15639921 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13390789 0,15632333 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13390789 0,15624752 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13390789 0,15617178 ! tube lumen formation GO:0035148 50 26 0,000 0,13390789 0,15609611 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13390789 0,15602052 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13390789 0,155945 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13390789 0,15586956 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13390789 0,15579419 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13390789 0,15571889 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13390789 0,15564366 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13390789 0,15556851 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13390789 0,15549343 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13390789 0,15541842 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13390789 0,15534348 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13390789 0,15526862 ! blastocyst development GO:0001824 49 26 0,000 0,13390789 0,15519382 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13390789 0,1551191 ! neuron fate commitment GO:0048663 48 27 0,000 0,13868577 0,1605765 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13868577 0,16049926 ! iron ion transport GO:0006826 59 27 0,000 0,13868577 0,1604221 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13868577 0,16034501 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13868577 0,160268 ! fat cell differentiation GO:0045444 50 27 0,000 0,13868577 0,16019105 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13868577 0,16011419 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13868577 0,16003739 ! autophagy GO:0006914 41 27 0,000 0,13868577 0,15996067 ! primary neural tube formation GO:0014020 51 27 0,000 0,13868577 0,15988403 ! base-excision repair GO:0006284 41 27 0,000 0,13868577 0,15980746 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13868577 0,15973096 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13868577 0,15965453 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13868577 0,15957818 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,13868577 0,1595019 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13868577 0,15942569 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14343746 0,16480923 ! circadian rhythm GO:0007623 50 28 0,000 0,14343746 0,16473056 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14343746 0,16465196 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14343746 0,16457345 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14343746 0,164495 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,14343746 0,16441664 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14343746 0,16433834 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14343746 0,16426012 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14343746 0,16418198 ! synaptogenesis GO:0007416 42 28 0,000 0,14343746 0,16410391 ! lipid oxidation GO:0034440 43 28 0,000 0,14343746 0,16402591 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14343746 0,16394799 ! translational initiation GO:0006413 65 29 0,000 0,14816308 0,16926893 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,14816308 0,1691886 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14816308 0,16910834 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,14816308 0,16902815 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14816308 0,16894805 ! catechol metabolic process GO:0009712 54 29 0,000 0,14816308 0,16886801 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14816308 0,16878806 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,14816308 0,16870818 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,14816308 0,16862837 ! cell fate determination GO:0001709 60 29 0,000 0,14816308 0,16854864 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14816308 0,16846899 ! detection of light stimulus GO:0009583 38 29 0,000 0,14816308 0,16838941 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,14816308 0,1683099 ! phenol metabolic process GO:0018958 55 30 0,000 0,15286279 0,17356672 ! zinc ion transport GO:0006829 45 30 0,000 0,15286279 0,17348485 ! membrane docking GO:0022406 61 30 0,000 0,15286279 0,17340306 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15286279 0,17332134 ! myofibril assembly GO:0030239 47 30 0,000 0,15286279 0,1732397 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15286279 0,17315814 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15286279 0,17307665 ! phospholipid transport GO:0015914 51 30 0,000 0,15286279 0,17299524 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15286279 0,17291391 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15286279 0,17283265 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15286279 0,17275147 ! eye morphogenesis GO:0048592 60 30 0,000 0,15286279 0,17267037 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,15753673 0,17786644 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,15753673 0,17778301 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,15753673 0,17769966 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,15753673 0,17761639 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,15753673 0,1775332 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,15753673 0,17745008 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,15753673 0,17736705 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,15753673 0,17728409 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,15753673 0,1772012 ! iron ion homeostasis GO:0055072 54 31 0,000 0,15753673 0,1771184 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,15753673 0,17703567 ! natural killer cell activation GO:0030101 45 31 0,000 0,15753673 0,17695302 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,15753673 0,17687045 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,15753673 0,17678796 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,15753673 0,17670554 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,15753673 0,1766232 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16218504 0,18174998 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16218504 0,18166536 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16218504 0,18158083 ! cholesterol transport GO:0030301 56 32 0,000 0,16218504 0,18149637 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16218504 0,18141199 ! spliceosome assembly GO:0000245 67 32 0,000 0,16218504 0,18132769 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16218504 0,18124347 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,16218504 0,18115933 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,16218504 0,18107527 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,16218504 0,18099128 ! muscle cell development GO:0055001 49 32 0,000 0,16218504 0,18090737 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16218504 0,18082354 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16218504 0,18073979 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,16218504 0,18065611 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16218504 0,18057251 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,16218504 0,18048899 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16218504 0,18040555 ! gene silencing GO:0016458 65 32 0,000 0,16218504 0,18032218 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,16680785 0,1853763 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16680785 0,18529071 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16680785 0,18520521 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16680785 0,18511978 ! sterol transport GO:0015918 57 33 0,000 0,16680785 0,18503443 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16680785 0,18494916 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16680785 0,18486397 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,16680785 0,18477886 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16680785 0,18469383 ! glial cell differentiation GO:0010001 63 34 0,000 0,17140531 0,18969695 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17140531 0,18960973 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17140531 0,18952259 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17140531 0,18943554 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17140531 0,18934856 ! mismatch repair GO:0006298 46 34 0,000 0,17140531 0,18926166 ! spermatid development GO:0007286 63 34 0,000 0,17140531 0,18917485 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17140531 0,18908811 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17140531 0,18900145 ! placenta development GO:0001890 53 34 0,000 0,17140531 0,18891487 ! odontogenesis GO:0042476 66 35 0,000 0,17597755 0,19386537 ! telencephalon development GO:0021537 68 35 0,000 0,17597755 0,19377665 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,17597755 0,193688 ! cytokine production GO:0001816 59 35 0,000 0,17597755 0,19359944 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17597755 0,19351096 ! neural tube formation GO:0001841 67 35 0,000 0,17597755 0,19342256 ! vesicle localization GO:0051648 64 35 0,000 0,17597755 0,19333424 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18052471 0,19823936 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18052471 0,19814893 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18052471 0,19805857 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18052471 0,1979683 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18052471 0,19787811 ! aerobic respiration GO:0009060 55 36 0,000 0,18052471 0,197788 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,18052471 0,19769797 ! embryonic organ development GO:0048568 57 36 0,000 0,18052471 0,19760803 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18052471 0,19751817 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18504693 0,20237405 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18504693 0,2022821 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18504693 0,20219024 ! organic anion transport GO:0015711 68 37 0,000 0,18504693 0,20209846 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18504693 0,20200676 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,18504693 0,20191515 ! spermatid differentiation GO:0048515 66 37 0,000 0,18504693 0,20182362 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18954434 0,20663511 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18954434 0,20654152 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18954434 0,20644802 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18954434 0,20635461 ! lipid homeostasis GO:0055088 67 38 0,000 0,18954434 0,20626128 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18954434 0,20616803 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,18954434 0,20607487 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18954434 0,20598179 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18954434 0,2058888 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18954434 0,20579589 ! glucan metabolic process GO:0044042 62 38 0,000 0,18954434 0,20570306 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,19401709 0,21046218 ! ion transmembrane transport GO:0034220 66 39 0,000 0,19401709 0,21036733 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,19401709 0,21027257 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,19401709 0,2101779 ! RNA modification GO:0009451 57 39 0,000 0,19401709 0,21008331 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,19401709 0,2099888 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19846529 0,21470661 ! feeding behavior GO:0007631 59 40 0,000 0,19846529 0,21461011 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,19846529 0,2145137 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,2028891 0,21919675 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,2028891 0,21909837 ! gliogenesis GO:0042063 88 41 0,000 0,2028891 0,21900007 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,2028891 0,21890187 ! polyol metabolic process GO:0019751 66 41 0,000 0,2028891 0,21880375 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,20728863 0,22344823 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,20728863 0,22334816 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,20728863 0,22324819 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,20728863 0,2231483 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,20728863 0,2230485 ! neuron migration GO:0001764 79 42 0,000 0,20728863 0,22294879 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,20728863 0,22284917 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,21166403 0,22745139 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,21166403 0,22734985 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,21166403 0,22724839 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,21166403 0,22714704 ! neural tube development GO:0021915 77 43 0,000 0,21166403 0,22704577 ! striated muscle contraction GO:0006941 77 43 0,000 0,21166403 0,22694459 ! phagocytosis GO:0006909 90 43 0,000 0,21166403 0,2268435 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21166403 0,2267425 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,21601542 0,23130089 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,21601542 0,231198 ! double-strand break repair GO:0006302 81 44 0,000 0,21601542 0,2310952 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,21601542 0,23099249 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22034294 0,23551538 ! glycolysis GO:0006096 65 45 0,000 0,22034294 0,2354108 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,22034294 0,23530631 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22034294 0,23520191 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22034294 0,23509761 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22034294 0,2349934 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22034294 0,23488928 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22034294 0,23478526 ! cell growth GO:0016049 84 45 0,000 0,22034294 0,23468132 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,22464671 0,23915929 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,22464671 0,23905351 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,22464671 0,23894783 ! response to calcium ion GO:0051592 81 47 0,000 0,22892687 0,24339286 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22892687 0,24328536 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,22892687 0,24317795 ! protein homooligomerization GO:0051260 76 47 0,000 0,22892687 0,24307063 ! Notch signaling pathway GO:0007219 96 48 0,000 0,23318354 0,24748108 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,23318354 0,24737196 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,23318354 0,24726294 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,23318354 0,24715401 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,23741686 0,25153014 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,23741686 0,25141944 ! regulation of ion transport GO:0043269 77 49 0,000 0,23741686 0,25130882 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,23741686 0,25119831 ! endocrine system development GO:0035270 104 49 0,000 0,23741686 0,25108789 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,23741686 0,25097757 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,23741686 0,25086735 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,23741686 0,25075723 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,24162694 0,25509189 ! neuromuscular process GO:0050905 99 50 0,000 0,24162694 0,25498001 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,24162694 0,25486822 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,24162694 0,25475654 ! viral infectious cycle GO:0019058 99 51 0,000 0,24581392 0,25905751 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,24581392 0,25894409 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24581392 0,25883076 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,24581392 0,25871754 ! amino acid activation GO:0043038 92 52 0,000 0,24997792 0,26298508 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,25411907 0,26722486 ! RNA catabolic process GO:0006401 93 53 0,000 0,25411907 0,26710812 ! regulation of translational initiation GO:0006446 82 53 0,000 0,25411907 0,26699148 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,25411907 0,26687494 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,25411907 0,2667585 ! cell maturation GO:0048469 100 53 0,000 0,25411907 0,26664217 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,25411907 0,26652593 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,25823749 0,27072741 ! cell recognition GO:0008037 85 54 0,000 0,25823749 0,2706095 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,25823749 0,27049169 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,25823749 0,27037398 ! chloride transport GO:0006821 90 55 0,000 0,26233331 0,27454282 ! glucose catabolic process GO:0006007 82 55 0,000 0,26233331 0,27442346 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,26233331 0,27430419 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,26233331 0,27418504 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,26233331 0,27406598 ! RNA elongation GO:0006354 79 55 0,000 0,26233331 0,27394703 ! nuclear export GO:0051168 97 55 0,000 0,26233331 0,27382818 ! regulation of actin filament length GO:0030832 105 56 0,000 0,26640665 0,27795941 ! sensory perception of smell GO:0007608 80 56 0,000 0,26640665 0,27783893 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,26640665 0,27771854 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,26640665 0,27759827 ! proton transport GO:0015992 94 56 0,000 0,26640665 0,2774781 ! hydrogen transport GO:0006818 97 58 0,000 0,27448637 0,28576989 ! regulation of endocytosis GO:0030100 91 58 0,000 0,27448637 0,28564629 ! adult behavior GO:0030534 99 58 0,000 0,27448637 0,28552279 ! regulation of cellular component size GO:0032535 109 59 0,000 0,278493 0,28956533 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,278493 0,28944024 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,278493 0,28931527 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,28247764 0,2933281 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,28247764 0,29320155 ! camera-type eye development GO:0043010 116 60 0,000 0,28247764 0,29307512 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2864404 0,29705845 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2864404 0,29693046 ! tRNA processing GO:0008033 89 61 0,000 0,2864404 0,29680258 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2864404 0,29667482 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29038141 0,30062722 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,29430078 0,30455384 ! detection of external stimulus GO:0009581 91 63 0,000 0,29430078 0,3044229 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,29430078 0,30429208 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,29430078 0,30416137 ! cell redox homeostasis GO:0045454 102 64 0,000 0,29819863 0,30805749 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29819863 0,30792528 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30207508 0,31179436 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,30207508 0,31166065 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,30207508 0,31152707 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,30207508 0,31139359 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,30593025 0,31523263 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,30593025 0,31509768 ! extracellular matrix organization GO:0030198 133 66 0,000 0,30593025 0,31496285 ! developmental maturation GO:0021700 116 66 0,000 0,30593025 0,31482814 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,30976425 0,31863736 ! hexose catabolic process GO:0019320 104 67 0,000 0,30976425 0,31850119 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,30976425 0,31836514 ! activation of immune response GO:0002253 105 67 0,000 0,30976425 0,3182292 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,3135772 0,32200885 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,3135772 0,32187148 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,3135772 0,32173422 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,3135772 0,32159708 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,31736921 0,32534739 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,31736921 0,32520883 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,31736921 0,32507038 ! antigen processing and presentation GO:0019882 104 69 0,000 0,31736921 0,32493205 ! appendage morphogenesis GO:0035107 135 70 0,000 0,3211404 0,32865326 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,32489088 0,33235011 ! appendage development GO:0048736 136 71 0,000 0,32489088 0,33220887 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,32489088 0,33206774 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,33233017 0,33952713 ! transition metal ion transport GO:0000041 126 74 0,000 0,3360192 0,34315034 ! neurotransmitter transport GO:0006836 123 74 0,000 0,3360192 0,34300475 ! exocytosis GO:0006887 133 74 0,000 0,3360192 0,34285928 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,3360192 0,34271394 ! eye development GO:0001654 143 74 0,000 0,3360192 0,34256873 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,33968797 0,34616233 ! defense response to bacterium GO:0042742 89 76 0,000 0,34333659 0,34973236 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,34333659 0,34958435 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,34696516 0,35312952 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,35057381 0,35665141 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,35416264 0,36015017 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,35416264 0,35999802 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,35773175 0,36347238 ! muscle cell differentiation GO:0042692 159 80 0,000 0,35773175 0,36331895 ! protein import into nucleus GO:0006606 158 80 0,000 0,35773175 0,36316565 ! inorganic anion transport GO:0015698 138 80 0,000 0,35773175 0,36301248 ! digestion GO:0007586 112 81 0,000 0,36128126 0,36645983 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,36128126 0,3663054 ! nuclear import GO:0051170 161 81 0,000 0,36128126 0,3661511 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,36481127 0,36957301 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,36481127 0,36941747 ! regulation of lyase activity GO:0051339 160 83 0,000 0,36832188 0,3728155 ! response to unfolded protein GO:0006986 131 85 0,000 0,37528536 0,37970419 ! nucleosome assembly GO:0006334 122 85 0,000 0,37528536 0,37954459 ! amine biosynthetic process GO:0009309 138 86 0,000 0,37873843 0,38287591 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,37873843 0,3827151 ! chromatin assembly GO:0031497 124 86 0,000 0,37873843 0,38255443 ! alcohol catabolic process GO:0046164 130 86 0,000 0,37873843 0,3823939 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,38217253 0,38569929 ! cellular respiration GO:0045333 135 88 0,000 0,38558776 0,38898287 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,38558776 0,38881984 ! cellular defense response GO:0006968 114 89 0,000 0,38898422 0,39208045 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,39236202 0,39531953 ! sterol metabolic process GO:0016125 152 91 0,000 0,39572126 0,3985372 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,39572126 0,39837044 ! nucleosome organization GO:0034728 138 92 0,000 0,39906204 0,40156557 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,39906204 0,40139769 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,40238446 0,40457042 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,40238446 0,40440143 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,40568863 0,40755192 ! transcription initiation GO:0006352 153 94 0,000 0,40568863 0,40738182 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,41224257 0,41379042 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,41224257 0,41361786 ! positive regulation of immune response GO:0050778 156 96 0,000 0,41224257 0,41344545 ! detection of stimulus GO:0051606 151 96 0,000 0,41224257 0,41327318 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,41549256 0,41635781 ! protein ubiquitination GO:0016567 217 97 0,000 0,41549256 0,41618447 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,41872468 0,41924743 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,41872468 0,41907303 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,42193903 0,42211447 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,42193903 0,42193903