pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6896-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 3,000 1,227E-08 2,823E-05 ! ribosomal large subunit biogenesis GO:0042273 12 12 3,000 2,881E-08 3,313E-05 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 2,000 2,193E-07 1,681E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 3,316E-07 1,906E-04 ! negative regulation of focal adhesion formation GO:0051895 16 6 2,000 4,376E-07 2,013E-04 ! protein heterooligomerization GO:0051291 10 7 2,000 7,643E-07 2,93E-04 ! regulation of focal adhesion formation GO:0051893 17 7 2,000 7,643E-07 2,511E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,22E-06 3,509E-04 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 2,000 1,22E-06 3,119E-04 ! establishment of cell polarity GO:0030010 12 9 2,000 1,827E-06 4,202E-04 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 2,000 2,605E-06 5,446E-04 GO:0010812|negative regulation of cell-substrate adhesion, ! angiogenesis GO:0001525 149 95 4,000 7,441E-06 1,426E-03 ! inositol metabolic process GO:0006020 20 14 2,000 7,837E-06 1,387E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 8,09E-06 1,329E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 3,000 9,644E-06 1,479E-03 ! cardiac muscle tissue development GO:0048738 23 15 2,000 9,777E-06 1,405E-03 ! RNA elongation GO:0006354 62 49 3,000 1,141E-05 1,543E-03 ! endothelial cell migration GO:0043542 22 16 2,000 1,201E-05 1,534E-03 ! lipid modification GO:0030258 73 50 3,000 1,237E-05 1,498E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 1,34E-05 1,541E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 1,455E-05 1,594E-03 ! positive regulation of cell motion GO:0051272 99 56 3,000 1,949E-05 2,037E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 2,065E-05 2,065E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 2,425E-05 2,324E-03 ! phosphoinositide metabolic process GO:0030384 87 60 3,000 2,566E-05 2,36E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 3,263E-05 2,886E-03 GO:0010810|regulation of cell-substrate adhesion, ! protein oligomerization GO:0051259 100 65 3,000 3,525E-05 3,003E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 4,271E-05 3,508E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 3,000 4,724E-05 3,746E-03 ! negative regulation of protein kinase cascade GO:0010741 51 26 2,000 5,464E-05 4,189E-03 ! positive regulation of catabolic process GO:0009896 40 28 2,000 6,857E-05 5,088E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 7,973E-05 5,731E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 7,973E-05 5,557E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 7,973E-05 5,394E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 7,973E-05 5,239E-03 ! regulation of cell adhesion GO:0030155 159 83 3,000 9,212E-05 5,885E-03 ! rRNA metabolic process GO:0016072 107 85 3,000 1,011E-04 6,283E-03 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 1,011E-04 6,118E-03 ! transcription initiation GO:0006352 118 85 3,000 1,011E-04 5,961E-03 ! regulation of protein stability GO:0031647 48 32 2,000 1,03E-04 5,922E-03 ! negative regulation of cell adhesion GO:0007162 67 33 2,000 1,131E-04 6,342E-03 ! cytokinesis GO:0000910 52 33 2,000 1,131E-04 6,191E-03 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 1,194E-04 6,385E-03 ! mRNA stabilization GO:0048255 15 6 1,000 1,194E-04 6,24E-03 GO:0043489|RNA stabilization, ! male sex determination GO:0030238 9 6 1,000 1,194E-04 6,101E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,194E-04 5,969E-03 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 1,238E-04 6,056E-03 ! polyol metabolic process GO:0019751 44 34 2,000 1,238E-04 5,93E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,238E-04 5,809E-03 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 1,351E-04 6,214E-03 ! glycerophospholipid metabolic process GO:0006650 130 92 3,000 1,374E-04 6,199E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,668E-04 7,379E-03 ! microtubule bundle formation GO:0001578 8 7 1,000 1,668E-04 7,239E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 1,668E-04 7,105E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 1,871E-04 7,825E-03 ! striated muscle contraction GO:0006941 62 41 2,000 2,174E-04 8,928E-03 ! induction of positive chemotaxis GO:0050930 14 8 1,000 2,22E-04 8,959E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 2,22E-04 8,804E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 2,22E-04 8,655E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,22E-04 8,511E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 2,22E-04 8,371E-03 ! regulation of embryonic development GO:0045995 16 8 1,000 2,22E-04 8,236E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 2,22E-04 8,106E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 2,336E-04 8,396E-03 ! response to insulin stimulus GO:0032868 63 43 2,000 2,506E-04 8,869E-03 ! negative regulation of cell migration GO:0030336 92 44 2,000 2,684E-04 9,355E-03 ! regulation of developmental growth GO:0048638 13 9 1,000 2,849E-04 9,781E-03 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 2,849E-04 9,637E-03 ! regulation of glycolysis GO:0006110 15 9 1,000 2,849E-04 9,498E-03 ! lung alveolus development GO:0048286 17 9 1,000 2,849E-04 9,362E-03 ! motor axon guidance GO:0008045 14 9 1,000 2,849E-04 9,23E-03 ! localization within membrane GO:0051668 15 9 1,000 2,849E-04 9,102E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 3,555E-04 0,01120119 ! blood vessel remodeling GO:0001974 21 10 1,000 3,555E-04 0,01104982 ! regulation of bone resorption GO:0045124 24 10 1,000 3,555E-04 0,01090249 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 3,555E-04 0,01075904 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 3,555E-04 0,01061931 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of intracellular transport GO:0032386 78 49 2,000 3,697E-04 0,0109013 ! negative regulation of cell motion GO:0051271 104 51 2,000 4,162E-04 0,01211716 ! virus-host interaction GO:0019048 17 11 1,000 4,337E-04 0,0124696 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 4,337E-04 0,01231566 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 4,337E-04 0,01216547 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 4,337E-04 0,01201889 ! regulation of mRNA processing GO:0050684 18 11 1,000 4,337E-04 0,01187581 ! regulation of leukocyte migration GO:0002685 24 11 1,000 4,337E-04 0,0117361 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 4,337E-04 0,01159963 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 5,195E-04 0,01373441 ! cartilage condensation GO:0001502 18 12 1,000 5,195E-04 0,01357834 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 5,195E-04 0,01342578 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of mRNA stability GO:0043488 27 12 1,000 5,195E-04 0,0132766 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 5,195E-04 0,0131307 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 5,778E-04 0,01444419 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 6,129E-04 0,01515664 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 6,129E-04 0,0149954 ! regulation of RNA stability GO:0043487 28 13 1,000 6,129E-04 0,01483755 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 7,137E-04 0,01709886 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 7,137E-04 0,01692258 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 7,137E-04 0,01674991 GO:0031114|regulation of microtubule depolymerization, ! lipid phosphorylation GO:0046834 23 15 1,000 8,22E-04 0,01909665 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 8,22E-04 0,01890568 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 8,22E-04 0,0187185 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 8,22E-04 0,01853498 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 8,22E-04 0,01835503 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 8,874E-04 0,01962505 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 9,377E-04 0,02054003 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 9,377E-04 0,02034626 ! regulation of catabolic process GO:0009894 106 70 2,000 1,053E-03 0,02263564 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 1,061E-03 0,02259075 ! neuromuscular junction development GO:0007528 23 17 1,000 1,061E-03 0,0223835 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 1,061E-03 0,02218001 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,061E-03 0,02198019 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,191E-03 0,02446219 ! negative regulation of T cell activation GO:0050868 25 18 1,000 1,191E-03 0,02424571 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 1,237E-03 0,02495847 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 1,329E-03 0,02657828 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,329E-03 0,02634916 GO:0010675|regulation of cellular carbohydrate metabolic process, ! sex determination GO:0007530 29 19 1,000 1,329E-03 0,02612395 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 1,329E-03 0,02590256 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 1,329E-03 0,02568489 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 1,329E-03 0,02547085 ! regulation of protein transport GO:0051223 114 76 2,000 1,336E-03 0,02539891 GO:0070201|regulation of establishment of protein localization, ! positive regulation of locomotion GO:0040017 35 20 1,000 1,474E-03 0,0277862 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 1,000 1,626E-03 0,0304058 ! regulation of chemotaxis GO:0050920 36 21 1,000 1,626E-03 0,03016059 ! dendrite development GO:0016358 35 21 1,000 1,626E-03 0,02991931 ! ossification GO:0001503 134 82 2,000 1,663E-03 0,03035907 GO:0060348|bone development, ! vasculogenesis GO:0001570 33 22 1,000 1,785E-03 0,03233386 ! regulation of behavior GO:0050795 38 22 1,000 1,785E-03 0,03208125 ! protein tetramerization GO:0051262 39 22 1,000 1,785E-03 0,03183256 ! regulation of protein localization GO:0032880 132 85 2,000 1,844E-03 0,03262064 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 1,952E-03 0,03426934 ! myelination GO:0042552 35 23 1,000 1,952E-03 0,03400973 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 1,952E-03 0,03375401 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 1,952E-03 0,03350212 ! interaction with host GO:0051701 37 23 1,000 1,952E-03 0,03325395 ! spermatid development GO:0007286 33 23 1,000 1,952E-03 0,03300944 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,125E-03 0,03568227 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 2,125E-03 0,0354237 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 2,125E-03 0,03516885 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 2,125E-03 0,03491765 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 2,306E-03 0,03761608 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 2,306E-03 0,03735118 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 2,494E-03 0,04010758 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 2,494E-03 0,03982905 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 2,494E-03 0,03955437 ! spermatid differentiation GO:0048515 36 26 1,000 2,494E-03 0,03928345 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 2,609E-03 0,04082242 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 2,688E-03 0,04177652 ! negative regulation of protein transport GO:0051224 49 27 1,000 2,688E-03 0,04149615 ! ensheathment of neurons GO:0007272 43 28 1,000 2,89E-03 0,04430935 GO:0008366|axon ensheathment, ! regulation of protein import into nucleus GO:0042306 53 29 1,000 3,098E-03 0,04719023 ! tissue homeostasis GO:0001894 42 29 1,000 3,098E-03 0,04687977 GO:0048871|multicellular organismal homeostasis, ! regulation of microtubule-based process GO:0032886 58 30 1,000 3,313E-03 0,04980914 ! negative regulation of cell activation GO:0050866 44 30 1,000 3,313E-03 0,04948571 ! mammary gland development GO:0030879 57 31 1,000 3,535E-03 0,05246153 ! peripheral nervous system development GO:0007422 53 32 1,000 3,764E-03 0,05549902 ! calcium-mediated signaling GO:0019722 50 32 1,000 3,764E-03 0,05514552 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 3,764E-03 0,0547965 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 4E-03 0,05785938 ! carbohydrate homeostasis GO:0033500 39 33 1,000 4E-03 0,05749776 GO:0042593|glucose homeostasis, ! androgen receptor signaling pathway GO:0030521 54 33 1,000 4E-03 0,05714063 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 4,242E-03 0,06022734 ! regulation of action potential in neuron GO:0019228 54 35 1,000 4,491E-03 0,06337008 ! protein homooligomerization GO:0051260 52 35 1,000 4,491E-03 0,06298367 ! tissue remodeling GO:0048771 62 36 1,000 4,747E-03 0,06616383 ! regulation of T cell proliferation GO:0042129 58 38 1,000 5,277E-03 0,07311897 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 5,552E-03 0,07647055 ! synapse organization GO:0050808 55 39 1,000 5,552E-03 0,07601537 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 5,834E-03 0,07939811 ! positive regulation of protein transport GO:0051222 55 40 1,000 5,834E-03 0,07893106 ! positive regulation of DNA binding GO:0043388 57 41 1,000 6,122E-03 0,08234362 ! regulation of T cell differentiation GO:0045580 59 41 1,000 6,122E-03 0,08186488 ! regulation of cell shape GO:0008360 78 42 1,000 6,416E-03 0,08530595 ! positive regulation of binding GO:0051099 59 43 1,000 6,717E-03 0,08879143 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 6,717E-03 0,08828405 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 6,717E-03 0,08778243 ! regulation of action potential GO:0001508 71 44 1,000 7,024E-03 0,09127688 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 7,024E-03 0,09076409 ! positive regulation of cell cycle GO:0045787 77 45 1,000 7,338E-03 0,09428349 ! vascular process in circulatory system GO:0003018 69 45 1,000 7,338E-03 0,09375969 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 7,657E-03 0,09730294 ! cell redox homeostasis GO:0045454 63 46 1,000 7,657E-03 0,09676831 ! response to UV GO:0009411 75 46 1,000 7,657E-03 0,09623952 ! negative regulation of immune system process GO:0002683 73 47 1,000 7,983E-03 0,09978905 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 7,983E-03 0,09924965 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! heart morphogenesis GO:0003007 65 48 1,000 8,315E-03 0,10282109 ! regulation of DNA replication GO:0006275 75 48 1,000 8,315E-03 0,10227124 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 8,315E-03 0,10172725 ! regulation of angiogenesis GO:0045765 94 49 1,000 8,653E-03 0,10530348 ! germ cell development GO:0007281 68 49 1,000 8,653E-03 0,10474925 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 8,653E-03 0,10420082 ! cartilage development GO:0051216 70 49 1,000 8,653E-03 0,10365811 ! skeletal muscle fiber development GO:0048741 73 50 1,000 8,997E-03 0,10722283 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 8,997E-03 0,10667014 ! positive regulation of growth GO:0045927 67 50 1,000 8,997E-03 0,10612311 ! activation of phospholipase C activity GO:0007202 87 51 1,000 9,348E-03 0,10969178 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 9,348E-03 0,10913497 ! regulation of protein catabolic process GO:0042176 77 51 1,000 9,348E-03 0,10858378 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 9,704E-03 0,11215588 ! nucleotide-excision repair GO:0006289 64 52 1,000 9,704E-03 0,1115951 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,01006618 0,11518516 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,01006618 0,11461493 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01043439 0,11822216 ! DNA catabolic process GO:0006308 67 54 1,000 0,01043439 0,11764264 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,01043439 0,11706877 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01043439 0,11650047 ! exocytosis GO:0006887 74 55 1,000 0,01080851 0,1200946 ! viral reproductive process GO:0022415 87 58 1,000 0,01196601 0,13231651 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,01196601 0,13168341 ! activation of MAPK activity GO:0000187 84 59 1,000 0,01236344 0,13540912 ! lung development GO:0030324 94 59 1,000 0,01236344 0,13476737 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01276661 0,13850564 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,01317548 0,1422704 ! respiratory tube development GO:0030323 99 62 1,000 0,01359001 0,1460609 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,01401019 0,14987642 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,01401019 0,14918254 ! viral reproduction GO:0016032 92 63 1,000 0,01401019 0,14849507 ! regulation of lipase activity GO:0060191 109 63 1,000 0,01401019 0,1478139 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01422047 0,14934744 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01422047 0,14866859 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01422047 0,14799588 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01422047 0,14732923 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01422047 0,14666856 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01422047 0,14601379 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01422047 0,14536484 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01422047 0,14472164 ! sleep GO:0030431 11 5 0,000 0,01422047 0,1440841 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01422047 0,14345215 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01422047 0,14282572 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01422047 0,14220474 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01422047 0,14158913 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01422047 0,14097883 ! tongue development GO:0043586 6 5 0,000 0,01422047 0,14037378 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01422047 0,13977389 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01422047 0,1391791 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01422047 0,13858936 ! cobalt ion transport GO:0006824 9 5 0,000 0,01422047 0,1380046 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01422047 0,13742475 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01422047 0,13684975 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01422047 0,13627954 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01422047 0,13571406 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01422047 0,13515326 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01422047 0,13459708 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01422047 0,13404545 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01422047 0,13349832 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01422047 0,13295565 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01422047 0,13241737 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01422047 0,13188343 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01422047 0,13135377 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01422047 0,13082836 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01422047 0,13030713 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01422047 0,12979004 ! malate metabolic process GO:0006108 7 5 0,000 0,01422047 0,12927703 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01422047 0,12876807 ! behavioral response to pain GO:0048266 7 5 0,000 0,01422047 0,1282631 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01422047 0,12776207 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01422047 0,12726494 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01422047 0,12677167 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01422047 0,1262822 ! mating behavior GO:0007617 6 5 0,000 0,01422047 0,1257965 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01422047 0,12531452 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01422047 0,12483622 ! rhythmic behavior GO:0007622 12 5 0,000 0,01422047 0,12436156 ! copulation GO:0007620 7 5 0,000 0,01422047 0,12389049 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01422047 0,12342298 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01422047 0,12295898 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01422047 0,12249846 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01422047 0,12204138 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01422047 0,12158769 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01422047 0,12113737 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01422047 0,12069037 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01422047 0,12024665 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01422047 0,11980619 ! response to protozoan GO:0001562 9 5 0,000 0,01422047 0,11936894 ! lymph vessel development GO:0001945 7 5 0,000 0,01422047 0,11893487 ! endochondral ossification GO:0001958 12 5 0,000 0,01422047 0,11850395 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01422047 0,11807614 ! parathyroid gland development GO:0060017 8 5 0,000 0,01422047 0,1176514 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01422047 0,11722971 ! anagen GO:0042640 6 5 0,000 0,01422047 0,11681103 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01422047 0,11639534 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01422047 0,11598259 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01422047 0,11557275 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01422047 0,11516581 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01422047 0,11476172 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01422047 0,11436045 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01422047 0,11396198 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01422047 0,11356628 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01422047 0,11317332 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01422047 0,11278307 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01422047 0,1123955 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01422047 0,11201058 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01422047 0,11162829 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01422047 0,1112486 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01422047 0,11087149 ! ovulation GO:0030728 6 5 0,000 0,01422047 0,11049692 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01422047 0,11012488 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01422047 0,10975533 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01422047 0,10938826 ! response to pH GO:0009268 9 5 0,000 0,01422047 0,10902363 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01422047 0,10866143 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01422047 0,10830162 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01422047 0,10794419 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01422047 0,10758911 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01422047 0,10723636 ! polyol catabolic process GO:0046174 7 5 0,000 0,01422047 0,10688591 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01422047 0,10653775 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01422047 0,10619185 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01422047 0,10584819 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01422047 0,10550674 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01422047 0,10516749 ! urea metabolic process GO:0019627 6 5 0,000 0,01422047 0,10483042 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01422047 0,10449549 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01422047 0,10416271 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01422047 0,10383203 ! neutrophil activation GO:0042119 5 5 0,000 0,01422047 0,10350345 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01422047 0,10317694 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01422047 0,10285248 ! response to food GO:0032094 5 5 0,000 0,01422047 0,10253006 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01422047 0,10220965 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01422047 0,10189124 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01422047 0,10157481 ! forebrain neuron development GO:0021884 7 5 0,000 0,01422047 0,10126034 ! melanosome organization GO:0032438 7 5 0,000 0,01422047 0,10094781 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01422047 0,1006372 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01422047 0,1003285 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01422047 0,10002168 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01422047 0,09971674 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01422047 0,09941365 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01422047 0,09911239 ! nucleoside transport GO:0015858 6 5 0,000 0,01422047 0,09881296 ! nucleoside salvage GO:0043174 7 5 0,000 0,01422047 0,09851533 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01422047 0,09821949 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01422047 0,09792542 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01422047 0,0976331 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01422047 0,09734253 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01422047 0,09705368 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01422047 0,09676654 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01422047 0,09648109 ! depyrimidination GO:0045008 8 5 0,000 0,01422047 0,09619732 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01422047 0,09591522 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01422047 0,09563476 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01422047 0,09535595 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01422047 0,09507875 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01422047 0,09480316 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01422047 0,09452916 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01422047 0,09425674 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01422047 0,09398589 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01422047 0,09371659 ! monocyte differentiation GO:0030224 8 5 0,000 0,01422047 0,09344883 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01422047 0,09318259 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01422047 0,09291787 ! centrosome duplication GO:0051298 5 5 0,000 0,01422047 0,09265464 ! response to UV-C GO:0010225 6 5 0,000 0,01422047 0,09239291 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01422047 0,09213265 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01422047 0,09187385 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01422047 0,0916165 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01422047 0,09136059 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01422047 0,0911061 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01422047 0,09085303 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01422047 0,09060136 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01422047 0,09035108 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01422047 0,09010218 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01422047 0,08985464 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01422047 0,08960846 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01422047 0,08936363 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01422047 0,08912014 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01422047 0,08887796 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01422047 0,0886371 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01422047 0,08839754 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01422047 0,08815927 ! neural tube patterning GO:0021532 6 5 0,000 0,01422047 0,08792228 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01422047 0,08768657 ! histone demethylation GO:0016577 9 5 0,000 0,01422047 0,08745211 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01422047 0,08721891 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01422047 0,08698694 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01422047 0,08675621 ! enteric nervous system development GO:0048484 8 5 0,000 0,01422047 0,08652669 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01422047 0,08629839 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01422047 0,08607129 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01422047 0,08584538 ! transcription termination GO:0006353 8 5 0,000 0,01422047 0,08562065 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01422047 0,0853971 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01422047 0,08517471 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01422047 0,08495348 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01422047 0,08473339 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01422047 0,08451444 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01422047 0,08429662 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01422047 0,08407992 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01422047 0,08386433 ! apical protein localization GO:0045176 6 5 0,000 0,01422047 0,08364985 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01422047 0,08343645 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01422047 0,08322415 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01422047 0,08301292 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01422047 0,08280276 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01422047 0,08259366 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01422047 0,08238562 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01422047 0,08217862 ! glial cell migration GO:0008347 10 5 0,000 0,01422047 0,08197266 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01422047 0,08176772 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01422047 0,08156381 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01422047 0,08136092 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01422047 0,08115903 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01422047 0,08095814 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01422047 0,08075825 ! neural plate development GO:0001840 6 5 0,000 0,01422047 0,08055933 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01422047 0,0803614 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01422047 0,08016444 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01422047 0,07996843 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01422047 0,07977339 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01422047 0,07957929 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01422047 0,07938614 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01422047 0,07919392 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01422047 0,07900263 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01422047 0,07881226 ! spindle assembly GO:0051225 5 5 0,000 0,01422047 0,07862281 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01422047 0,07843427 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01422047 0,07824663 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01422047 0,07805988 ! organ regeneration GO:0031100 7 5 0,000 0,01422047 0,07787402 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01422047 0,07768905 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01422047 0,07750495 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01422047 0,07732172 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01422047 0,07713936 GO:0055081|anion homeostasis, ! respiratory system development GO:0060541 100 64 1,000 0,01443596 0,07812402 ! adaptive immune response GO:0002250 94 64 1,000 0,01443596 0,07794063 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 1,000 0,0148673 0,08008147 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,01530417 0,08224205 ! axon guidance GO:0007411 99 66 1,000 0,01530417 0,08205034 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,01574654 0,08422569 ! tRNA transcription GO:0009304 11 6 0,000 0,01704069 0,09093641 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01704069 0,09072591 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01704069 0,09051638 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01704069 0,09030782 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01704069 0,09010022 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01704069 0,08989357 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01704069 0,08968786 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01704069 0,08948309 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01704069 0,08927926 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01704069 0,08907635 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01704069 0,08887436 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01704069 0,08867329 ! prostate gland development GO:0030850 9 6 0,000 0,01704069 0,08847313 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01704069 0,08827386 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01704069 0,08807549 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01704069 0,08787801 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01704069 0,08768142 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01704069 0,0874857 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01704069 0,08729086 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01704069 0,08709688 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01704069 0,08690376 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01704069 0,08671149 ! neuron adhesion GO:0007158 9 6 0,000 0,01704069 0,08652008 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01704069 0,0863295 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01704069 0,08613977 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01704069 0,08595087 ! signal peptide processing GO:0006465 8 6 0,000 0,01704069 0,08576279 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01704069 0,08557553 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01704069 0,08538909 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01704069 0,08520347 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01704069 0,08501864 ! opsonization GO:0008228 8 6 0,000 0,01704069 0,08483462 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01704069 0,08465139 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01704069 0,08446895 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01704069 0,0842873 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01704069 0,08410643 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01704069 0,08392633 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01704069 0,083747 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01704069 0,08356843 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01704069 0,08339063 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01704069 0,08321358 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01704069 0,08303728 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01704069 0,08286172 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01704069 0,08268691 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01704069 0,08251283 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01704069 0,08233948 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01704069 0,08216686 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01704069 0,08199497 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01704069 0,08182379 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01704069 0,08165332 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01704069 0,08148356 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01704069 0,08131451 ! thymic T cell selection GO:0045061 12 6 0,000 0,01704069 0,08114616 ! protein lipoylation GO:0009249 10 6 0,000 0,01704069 0,0809785 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01704069 0,08081153 ! pigment granule organization GO:0048753 11 6 0,000 0,01704069 0,08064526 ! drug transport GO:0015893 6 6 0,000 0,01704069 0,08047966 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01704069 0,08031474 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01704069 0,0801505 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01704069 0,07998693 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01704069 0,07982402 ! histidine metabolic process GO:0006547 6 6 0,000 0,01704069 0,07966178 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01704069 0,07950019 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01704069 0,07933926 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01704069 0,07917898 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01704069 0,07901934 ! adenohypophysis development GO:0021984 10 6 0,000 0,01704069 0,07886035 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01704069 0,078702 ! hyperosmotic response GO:0006972 8 6 0,000 0,01704069 0,07854428 ! microtubule nucleation GO:0007020 10 6 0,000 0,01704069 0,07838719 ! ER overload response GO:0006983 7 6 0,000 0,01704069 0,07823073 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01704069 0,07807489 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01704069 0,07791967 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01704069 0,07776507 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01704069 0,07761108 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01704069 0,0774577 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01704069 0,07730492 ! response to dietary excess GO:0002021 7 6 0,000 0,01704069 0,07715274 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01704069 0,07700117 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01704069 0,07685019 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01704069 0,07669979 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01704069 0,07654999 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01704069 0,07640077 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01704069 0,07625213 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01704069 0,07610407 ! neuron apoptosis GO:0051402 8 6 0,000 0,01704069 0,07595658 ! organic alcohol transport GO:0015850 9 6 0,000 0,01704069 0,07580966 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01704069 0,07566331 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01704069 0,07551752 ! carnitine transport GO:0015879 8 6 0,000 0,01704069 0,0753723 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01704069 0,07522763 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01704069 0,07508351 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01704069 0,07493995 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01704069 0,07479694 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01704069 0,07465447 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01704069 0,07451254 ! parturition GO:0007567 12 6 0,000 0,01704069 0,07437115 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01704069 0,07423029 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01704069 0,07408997 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01704069 0,07395018 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01704069 0,07381091 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01704069 0,07367217 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01704069 0,07353395 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01704069 0,07339624 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01704069 0,07325906 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01704069 0,07312238 ! macrophage differentiation GO:0030225 10 6 0,000 0,01704069 0,07298621 ! astrocyte development GO:0014002 14 6 0,000 0,01704069 0,07285055 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01704069 0,07271539 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01704069 0,07258073 ! interaction with symbiont GO:0051702 8 6 0,000 0,01704069 0,07244657 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01704069 0,0723129 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01704069 0,07217973 ! eating behavior GO:0042755 6 6 0,000 0,01704069 0,07204705 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01704069 0,07191485 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01704069 0,07178314 ! response to copper ion GO:0046688 9 6 0,000 0,01704069 0,07165191 ! DNA topological change GO:0006265 8 6 0,000 0,01704069 0,07152116 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01704069 0,07139088 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01704069 0,07126108 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01704069 0,07113175 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01704069 0,07100289 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01704069 0,07087449 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01704069 0,07074656 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01704069 0,07061909 ! gas homeostasis GO:0033483 11 6 0,000 0,01704069 0,07049208 ! hair follicle maturation GO:0048820 7 6 0,000 0,01704069 0,07036552 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01704069 0,07023942 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01704069 0,07011376 ! Schwann cell development GO:0014044 14 6 0,000 0,01704069 0,06998856 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01704069 0,0698638 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01704069 0,06973949 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01704069 0,06961562 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01704069 0,06949219 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01704069 0,06936919 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01704069 0,06924663 ! histone ubiquitination GO:0016574 7 6 0,000 0,01704069 0,06912451 ! regulation of meiosis GO:0040020 10 6 0,000 0,01704069 0,06900281 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01704069 0,06888154 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01704069 0,06876069 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01704069 0,06864027 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01704069 0,06852027 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01704069 0,06840069 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01704069 0,06828152 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01704069 0,06816277 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01704069 0,06804443 ! receptor internalization GO:0031623 9 6 0,000 0,01704069 0,06792651 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01704069 0,06780899 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01704069 0,06769187 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01704069 0,06757516 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01704069 0,06745885 ! protein deubiquitination GO:0016579 8 6 0,000 0,01704069 0,06734295 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01704069 0,06722743 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01704069 0,06711232 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01704069 0,0669976 ! axonal fasciculation GO:0007413 9 6 0,000 0,01704069 0,06688327 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01704069 0,06676933 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01704069 0,06665577 ! midbrain development GO:0030901 6 6 0,000 0,01704069 0,06654261 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01704069 0,06642982 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01704069 0,06631742 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01704069 0,0662054 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01704069 0,06609375 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01704069 0,06598248 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01704069 0,06587159 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01704069 0,06576106 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01704069 0,06565091 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01704069 0,06554113 ! adult feeding behavior GO:0008343 6 6 0,000 0,01704069 0,06543171 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01704069 0,06532266 ! blastocyst growth GO:0001832 15 6 0,000 0,01704069 0,06521397 ! pigment granule transport GO:0051904 12 6 0,000 0,01704069 0,06510564 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01704069 0,06499767 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01704069 0,06489006 ! catecholamine transport GO:0051937 7 6 0,000 0,01704069 0,0647828 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01704069 0,0646759 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01704069 0,06456935 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01704069 0,06446315 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01704069 0,0643573 ! protein prenylation GO:0018342 10 6 0,000 0,01704069 0,06425179 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01704069 0,06414664 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01704069 0,06404182 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01704069 0,06393735 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01704069 0,06383322 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,01710631 0,06397482 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,01757034 0,06560354 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,0180397 0,06724685 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,0180397 0,06713804 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,0180397 0,06702958 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,0180397 0,06692146 ! negative regulation of transport GO:0051051 116 73 1,000 0,01851436 0,0685717 ! response to oxygen levels GO:0070482 137 74 1,000 0,01899428 0,07023609 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01985301 0,0732936 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01985301 0,07317614 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01985301 0,07305906 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01985301 0,07294235 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01985301 0,07282602 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01985301 0,07271005 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01985301 0,07259445 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01985301 0,07247923 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01985301 0,07236436 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01985301 0,07224986 ! reproductive behavior GO:0019098 12 7 0,000 0,01985301 0,07213572 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01985301 0,07202194 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01985301 0,07190852 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01985301 0,07179546 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01985301 0,07168275 ! oligopeptide transport GO:0006857 11 7 0,000 0,01985301 0,0715704 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01985301 0,07145839 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01985301 0,07134674 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01985301 0,07123543 ! RNA methylation GO:0001510 11 7 0,000 0,01985301 0,07112447 ! pericardium development GO:0060039 8 7 0,000 0,01985301 0,07101386 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01985301 0,07090359 ! fibril organization GO:0043206 13 7 0,000 0,01985301 0,07079366 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01985301 0,07068407 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01985301 0,07057483 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01985301 0,07046591 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01985301 0,07035734 ! lipoprotein transport GO:0042953 9 7 0,000 0,01985301 0,0702491 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01985301 0,07014119 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01985301 0,07003361 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01985301 0,06992636 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01985301 0,06981944 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01985301 0,06971284 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01985301 0,06960657 ! chemosensory behavior GO:0007635 9 7 0,000 0,01985301 0,06950063 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01985301 0,069395 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01985301 0,0692897 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01985301 0,06918472 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01985301 0,06908005 ! reflex GO:0060004 12 7 0,000 0,01985301 0,0689757 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01985301 0,06887166 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01985301 0,06876794 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01985301 0,06866453 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01985301 0,06856143 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01985301 0,06845864 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01985301 0,06835616 ! spinal cord patterning GO:0021511 7 7 0,000 0,01985301 0,06825398 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01985301 0,06815211 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01985301 0,06805054 ! adrenal gland development GO:0030325 17 7 0,000 0,01985301 0,06794927 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01985301 0,06784831 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01985301 0,06774764 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01985301 0,06764728 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01985301 0,06754721 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01985301 0,06744743 ! endosome organization GO:0007032 10 7 0,000 0,01985301 0,06734795 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01985301 0,06724877 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01985301 0,06714987 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01985301 0,06705127 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01985301 0,06695295 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01985301 0,06685492 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01985301 0,06675718 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01985301 0,06665973 ! galactose metabolic process GO:0006012 10 7 0,000 0,01985301 0,06656255 ! vesicle fusion GO:0006906 15 7 0,000 0,01985301 0,06646567 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01985301 0,06636906 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01985301 0,06627273 ! organ growth GO:0035265 11 7 0,000 0,01985301 0,06617668 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01985301 0,06608091 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01985301 0,06598542 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01985301 0,06589021 ! retinol metabolic process GO:0042572 9 7 0,000 0,01985301 0,06579526 ! behavioral fear response GO:0001662 13 7 0,000 0,01985301 0,06570059 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01985301 0,0656062 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01985301 0,06551207 ! rRNA modification GO:0000154 12 7 0,000 0,01985301 0,06541821 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01985301 0,06532462 ! response to UV-B GO:0010224 11 7 0,000 0,01985301 0,0652313 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01985301 0,06513825 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01985301 0,06504546 ! intermediate filament organization GO:0045109 11 7 0,000 0,01985301 0,06495293 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01985301 0,06486067 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01985301 0,06476867 ! fibrinolysis GO:0042730 9 7 0,000 0,01985301 0,06467693 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01985301 0,06458545 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01985301 0,06449423 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01985301 0,06440326 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01985301 0,06431255 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01985301 0,0642221 ! response to tropane GO:0014073 13 7 0,000 0,01985301 0,0641319 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01985301 0,06404195 ! melanosome localization GO:0032400 10 7 0,000 0,01985301 0,06395226 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01985301 0,06386281 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01985301 0,06377362 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01985301 0,06368468 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01985301 0,06359598 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01985301 0,06350753 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01985301 0,06341932 ! mast cell activation GO:0045576 9 7 0,000 0,01985301 0,06333136 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01985301 0,06324365 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01985301 0,06315617 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01985301 0,06306894 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01985301 0,06298195 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01985301 0,0628952 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01985301 0,06280868 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01985301 0,06272241 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01985301 0,06263637 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01985301 0,06255056 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01985301 0,062465 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01985301 0,06237966 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01985301 0,06229456 ! response to tumor cell GO:0002347 12 7 0,000 0,01985301 0,06220969 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01985301 0,06212505 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01985301 0,06204064 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01985301 0,06195646 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01985301 0,06187251 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01985301 0,06178879 ! diuresis GO:0030146 12 7 0,000 0,01985301 0,06170529 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01985301 0,06162201 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01985301 0,06153897 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01985301 0,06145614 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01985301 0,06137354 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01985301 0,06129116 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01985301 0,061209 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01985301 0,06112706 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01985301 0,06104534 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01985301 0,06096383 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01985301 0,06088255 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01985301 0,06080148 ! lymph node development GO:0048535 9 7 0,000 0,01985301 0,06072063 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01985301 0,06063999 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01985301 0,06055957 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01985301 0,06047935 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01985301 0,06039935 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01985301 0,06031957 ! ATP catabolic process GO:0006200 10 7 0,000 0,01985301 0,06023999 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01985301 0,06016062 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01985301 0,06008146 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01985301 0,06000251 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01985301 0,05992377 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01985301 0,05984523 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01985301 0,0597669 ! muscle adaptation GO:0043500 12 7 0,000 0,01985301 0,05968877 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01985301 0,05961085 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01985301 0,05953313 ! retina homeostasis GO:0001895 9 7 0,000 0,01985301 0,05945561 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01985301 0,0593783 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01985301 0,05930118 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01985301 0,05922427 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01985301 0,05914755 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01985301 0,05907104 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01985301 0,05899472 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01985301 0,0589186 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,0199698 0,05918883 ! regulation of DNA binding GO:0051101 119 77 1,000 0,02046532 0,06057946 ! gland development GO:0048732 148 77 1,000 0,02046532 0,0605016 ! protein ubiquitination GO:0016567 125 77 1,000 0,02046532 0,06042393 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,02046532 0,06034647 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02265743 0,06672483 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02265743 0,0666395 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02265743 0,0665544 ! axon extension GO:0048675 11 8 0,000 0,02265743 0,06646951 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02265743 0,06638483 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02265743 0,06630037 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02265743 0,06621613 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02265743 0,0661321 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02265743 0,06604828 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02265743 0,06596467 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02265743 0,06588128 ! phosphate transport GO:0006817 10 8 0,000 0,02265743 0,0657981 ! N-glycan processing GO:0006491 12 8 0,000 0,02265743 0,06571512 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02265743 0,06563236 ! UTP metabolic process GO:0046051 8 8 0,000 0,02265743 0,0655498 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02265743 0,06546745 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02265743 0,06538531 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02265743 0,06530337 ! succinate metabolic process GO:0006105 14 8 0,000 0,02265743 0,06522164 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02265743 0,06514012 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02265743 0,06505879 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02265743 0,06497767 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02265743 0,06489675 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02265743 0,06481604 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02265743 0,06473552 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02265743 0,0646552 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02265743 0,06457508 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02265743 0,06449516 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02265743 0,06441544 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02265743 0,06433592 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02265743 0,06425659 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02265743 0,06417745 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02265743 0,06409851 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02265743 0,06401977 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02265743 0,06394122 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02265743 0,06386286 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02265743 0,06378469 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02265743 0,06370671 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02265743 0,06362893 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02265743 0,06355133 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02265743 0,06347393 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02265743 0,06339671 ! melanin metabolic process GO:0006582 12 8 0,000 0,02265743 0,06331968 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02265743 0,06324283 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02265743 0,06316617 ! macrophage activation GO:0042116 12 8 0,000 0,02265743 0,0630897 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02265743 0,06301341 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02265743 0,06293731 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02265743 0,06286139 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02265743 0,06278565 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02265743 0,0627101 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02265743 0,06263473 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02265743 0,06255954 ! ruffle organization GO:0031529 11 8 0,000 0,02265743 0,06248452 ! osteoblast development GO:0002076 13 8 0,000 0,02265743 0,06240969 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02265743 0,06233504 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02265743 0,06226056 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02265743 0,06218627 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02265743 0,06211215 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02265743 0,06203821 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02265743 0,06196444 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02265743 0,06189085 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02265743 0,06181743 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02265743 0,06174419 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02265743 0,06167112 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02265743 0,06159822 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02265743 0,06152549 ! segment specification GO:0007379 10 8 0,000 0,02265743 0,06145294 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02265743 0,06138056 ! cellular extravasation GO:0045123 11 8 0,000 0,02265743 0,06130834 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02265743 0,0612363 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02265743 0,06116443 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02265743 0,06109272 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02265743 0,06102119 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02265743 0,06094982 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02265743 0,06087861 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02265743 0,06080758 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02265743 0,0607367 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02265743 0,060666 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02265743 0,06059546 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02265743 0,06052508 ! icosanoid secretion GO:0032309 12 8 0,000 0,02265743 0,06045486 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02265743 0,06038481 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02265743 0,06031492 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02265743 0,06024519 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02265743 0,06017563 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02265743 0,06010622 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02265743 0,06003697 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02265743 0,05996789 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02265743 0,05989896 ! sterol catabolic process GO:0016127 9 8 0,000 0,02265743 0,05983019 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02265743 0,05976157 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02265743 0,05969312 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02265743 0,05962482 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02265743 0,05955668 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02265743 0,05948869 ! prophase GO:0051324 11 8 0,000 0,02265743 0,05942086 ! S phase GO:0051320 8 8 0,000 0,02265743 0,05935318 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02265743 0,05928566 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02265743 0,05921829 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02265743 0,05915107 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02265743 0,05908401 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02265743 0,05901709 ! hormone catabolic process GO:0042447 13 8 0,000 0,02265743 0,05895033 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02265743 0,05888372 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02265743 0,05881726 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02265743 0,05875095 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02265743 0,05868479 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02265743 0,05861878 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02265743 0,05855291 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02265743 0,0584872 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02265743 0,05842163 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02265743 0,05835621 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02265743 0,05829093 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02265743 0,0582258 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02265743 0,05816082 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02265743 0,05809598 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02265743 0,05803128 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,024076 0,06159601 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,02461172 0,06289662 ! regulation of membrane potential GO:0042391 128 85 1,000 0,02461172 0,06282681 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,02461172 0,06275716 ! cell cycle arrest GO:0007050 150 86 1,000 0,02515232 0,0640646 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,02515232 0,06399373 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02545399 0,06468971 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02545399 0,06461831 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02545399 0,06454706 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02545399 0,06447598 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02545399 0,06440504 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02545399 0,06433427 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02545399 0,06426365 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02545399 0,06419319 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02545399 0,06412288 ! GTP metabolic process GO:0046039 9 9 0,000 0,02545399 0,06405272 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02545399 0,06398272 ! social behavior GO:0035176 14 9 0,000 0,02545399 0,06391287 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02545399 0,06384317 ! artery development GO:0060840 19 9 0,000 0,02545399 0,06377362 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02545399 0,06370423 ! response to pain GO:0048265 16 9 0,000 0,02545399 0,06363498 ! protein complex disassembly GO:0043241 17 9 0,000 0,02545399 0,06356589 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02545399 0,06349695 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02545399 0,06342815 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02545399 0,06335951 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02545399 0,06329101 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02545399 0,06322266 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02545399 0,06315446 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02545399 0,06308641 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02545399 0,0630185 ! protein targeting to ER GO:0045047 19 9 0,000 0,02545399 0,06295074 ! T cell selection GO:0045058 18 9 0,000 0,02545399 0,06288312 ! endoderm development GO:0007492 12 9 0,000 0,02545399 0,06281565 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02545399 0,06274832 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02545399 0,06268114 ! arginine catabolic process GO:0006527 10 9 0,000 0,02545399 0,0626141 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02545399 0,06254721 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02545399 0,06248045 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02545399 0,06241384 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02545399 0,06234738 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02545399 0,06228105 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02545399 0,06221486 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02545399 0,06214882 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02545399 0,06208291 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02545399 0,06201715 ! mannose metabolic process GO:0006013 9 9 0,000 0,02545399 0,06195152 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02545399 0,06188603 ! receptor clustering GO:0043113 15 9 0,000 0,02545399 0,06182068 ! epithelial cell development GO:0002064 10 9 0,000 0,02545399 0,06175547 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02545399 0,0616904 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02545399 0,06162546 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02545399 0,06156066 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02545399 0,06149599 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02545399 0,06143146 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02545399 0,06136707 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02545399 0,06130281 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02545399 0,06123869 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02545399 0,0611747 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02545399 0,06111084 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02545399 0,06104712 ! DNA ligation GO:0006266 14 9 0,000 0,02545399 0,06098353 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02545399 0,06092007 ! response to amine stimulus GO:0014075 13 9 0,000 0,02545399 0,06085674 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02545399 0,06079355 ! erythrocyte development GO:0048821 11 9 0,000 0,02545399 0,06073048 ! renal water homeostasis GO:0003091 14 9 0,000 0,02545399 0,06066755 ! postreplication repair GO:0006301 11 9 0,000 0,02545399 0,06060475 ! mRNA cleavage GO:0006379 13 9 0,000 0,02545399 0,06054207 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02545399 0,06047953 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02545399 0,06041712 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02545399 0,06035483 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02545399 0,06029267 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02545399 0,06023064 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02545399 0,06016874 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02545399 0,06010697 ! acid secretion GO:0046717 14 9 0,000 0,02545399 0,06004532 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02545399 0,0599838 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02545399 0,0599224 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02545399 0,05986113 ! purine base metabolic process GO:0006144 18 9 0,000 0,02545399 0,05979999 ! oocyte differentiation GO:0009994 12 9 0,000 0,02545399 0,05973897 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02545399 0,05967807 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02545399 0,0596173 ! spleen development GO:0048536 15 9 0,000 0,02545399 0,05955665 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02545399 0,05949612 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02545399 0,05943572 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02545399 0,05937544 ! detection of calcium ion GO:0005513 13 9 0,000 0,02545399 0,05931528 ! blastocyst formation GO:0001825 12 9 0,000 0,02545399 0,05925525 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02545399 0,05919533 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02545399 0,05913554 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02545399 0,05907587 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02545399 0,05901632 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02545399 0,05895688 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02545399 0,05889757 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02545399 0,05883838 ! prepulse inhibition GO:0060134 14 9 0,000 0,02545399 0,0587793 ! embryonic placenta development GO:0001892 12 9 0,000 0,02545399 0,05872035 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02545399 0,05866151 ! insulin secretion GO:0030073 17 9 0,000 0,02545399 0,05860279 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02545399 0,05854419 ! response to nicotine GO:0035094 16 9 0,000 0,02545399 0,0584857 ! nucleus localization GO:0051647 15 9 0,000 0,02545399 0,05842733 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02545399 0,05836908 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,02569777 0,05886939 GO:0060538|skeletal muscle organ development, ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,02624804 0,06007013 ! interphase GO:0051325 159 88 1,000 0,02624804 0,06001042 ! reproductive developmental process GO:0003006 127 89 1,000 0,02680309 0,06121859 ! regulation of T cell activation GO:0050863 128 89 1,000 0,02680309 0,06115786 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,02736291 0,06237334 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02824271 0,06431509 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02824271 0,06425148 ! neuron fate specification GO:0048665 11 10 0,000 0,02824271 0,06418799 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02824271 0,06412462 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02824271 0,06406138 ! thyroid gland development GO:0030878 19 10 0,000 0,02824271 0,06399827 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02824271 0,06393528 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02824271 0,06387241 ! synapsis GO:0007129 13 10 0,000 0,02824271 0,06380967 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02824271 0,06374705 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02824271 0,06368455 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02824271 0,06362218 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02824271 0,06355992 ! sulfate transport GO:0008272 12 10 0,000 0,02824271 0,06349779 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02824271 0,06343578 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02824271 0,06337389 ! androgen metabolic process GO:0008209 13 10 0,000 0,02824271 0,06331213 ! phospholipid efflux GO:0033700 16 10 0,000 0,02824271 0,06325048 ! hippocampus development GO:0021766 19 10 0,000 0,02824271 0,06318895 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02824271 0,06312754 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02824271 0,06306625 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02824271 0,06300508 ! pathogenesis GO:0009405 13 10 0,000 0,02824271 0,06294403 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02824271 0,0628831 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02824271 0,06282228 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02824271 0,06276159 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02824271 0,06270101 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02824271 0,06264054 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02824271 0,06258019 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02824271 0,06251996 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02824271 0,06245985 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02824271 0,06239985 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02824271 0,06233996 ! response to X-ray GO:0010165 16 10 0,000 0,02824271 0,06228019 ! B cell proliferation GO:0042100 14 10 0,000 0,02824271 0,06222054 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02824271 0,062161 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02824271 0,06210157 ! forebrain cell migration GO:0021885 17 10 0,000 0,02824271 0,06204226 ! lipid digestion GO:0044241 15 10 0,000 0,02824271 0,06198305 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02824271 0,06192397 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02824271 0,06186499 ! UV protection GO:0009650 14 10 0,000 0,02824271 0,06180613 ! entry into host cell GO:0030260 20 10 0,000 0,02824271 0,06174738 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02824271 0,06168874 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02824271 0,06163021 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02824271 0,06157179 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02824271 0,06151349 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02824271 0,06145529 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02824271 0,0613972 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02824271 0,06133923 ! regulation of organ growth GO:0046620 11 10 0,000 0,02824271 0,06128136 ! response to dsRNA GO:0043331 18 10 0,000 0,02824271 0,0612236 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02824271 0,06116595 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02824271 0,06110841 ! embryonic axis specification GO:0000578 12 10 0,000 0,02824271 0,06105098 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02824271 0,06099365 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02824271 0,06093644 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02824271 0,06087933 ! cranial nerve development GO:0021545 12 10 0,000 0,02824271 0,06082232 ! fucose catabolic process GO:0019317 16 10 0,000 0,02824271 0,06076543 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02824271 0,06070864 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02824271 0,06065195 ! protein sumoylation GO:0016925 12 10 0,000 0,02824271 0,06059537 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02824271 0,0605389 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02824271 0,06048253 ! zymogen activation GO:0031638 14 10 0,000 0,02824271 0,06042627 ! salivary gland development GO:0007431 22 10 0,000 0,02824271 0,06037011 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02824271 0,06031406 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02824271 0,06025811 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02824271 0,06020226 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02824271 0,06014652 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02824271 0,06009088 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02824271 0,06003534 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02824271 0,05997991 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02824271 0,05992458 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02824271 0,05986935 ! detection of bacterium GO:0016045 10 10 0,000 0,02824271 0,05981422 ! embryonic gut development GO:0048566 11 10 0,000 0,02824271 0,05975919 ! activation of innate immune response GO:0002218 10 10 0,000 0,02824271 0,05970427 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02824271 0,05964944 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02824271 0,05959472 ! developmental induction GO:0031128 13 10 0,000 0,02824271 0,05954009 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02824271 0,05948557 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02824271 0,05943114 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02824271 0,05937682 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02824271 0,05932259 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,0290706 0,06100583 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,0290706 0,06095022 ! electron transport chain GO:0022900 123 94 1,000 0,02964915 0,06210659 ! regulation of binding GO:0051098 151 95 1,000 0,0302323 0,06327051 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,03082003 0,06444188 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,03082003 0,06438335 ! response to light stimulus GO:0009416 153 96 1,000 0,03082003 0,06432492 ! rRNA transcription GO:0009303 17 11 0,000 0,03102361 0,06469112 ! respiratory burst GO:0045730 14 11 0,000 0,03102361 0,06463253 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03102361 0,06457403 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03102361 0,06451565 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03102361 0,06445737 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03102361 0,0643992 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03102361 0,06434113 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03102361 0,06428316 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03102361 0,0642253 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03102361 0,06416754 ! mating GO:0007618 14 11 0,000 0,03102361 0,06410989 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03102361 0,06405234 ! T cell proliferation GO:0042098 20 11 0,000 0,03102361 0,0639949 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03102361 0,06393755 ! bone resorption GO:0045453 16 11 0,000 0,03102361 0,06388031 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03102361 0,06382317 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03102361 0,06376614 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03102361 0,0637092 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03102361 0,06365237 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03102361 0,06359564 ! syncytium formation GO:0006949 15 11 0,000 0,03102361 0,06353901 ! plasma membrane organization GO:0007009 18 11 0,000 0,03102361 0,06348248 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03102361 0,06342605 ! focal adhesion formation GO:0048041 24 11 0,000 0,03102361 0,06336972 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03102361 0,06331349 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03102361 0,06325737 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03102361 0,06320134 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03102361 0,06314541 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03102361 0,06308957 ! adult heart development GO:0007512 11 11 0,000 0,03102361 0,06303384 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03102361 0,06297821 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,03102361 0,06292267 ! temperature homeostasis GO:0001659 16 11 0,000 0,03102361 0,06286723 ! L-glutamate transport GO:0015813 16 11 0,000 0,03102361 0,06281189 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03102361 0,06275665 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03102361 0,0627015 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03102361 0,06264645 ! stem cell development GO:0048864 29 11 0,000 0,03102361 0,0625915 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03102361 0,06253664 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03102361 0,06248188 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03102361 0,06242722 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03102361 0,06237265 ! vasoconstriction GO:0042310 15 11 0,000 0,03102361 0,06231817 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03102361 0,06226379 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03102361 0,06220951 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03102361 0,06215532 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03102361 0,06210123 ! ribosome assembly GO:0042255 13 11 0,000 0,03102361 0,06204722 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03102361 0,06199332 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03102361 0,0619395 ! chromatin silencing GO:0006342 19 11 0,000 0,03102361 0,06188578 ! nucleosome positioning GO:0016584 13 11 0,000 0,03102361 0,06183216 ! T cell homeostasis GO:0043029 20 11 0,000 0,03102361 0,06177862 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03102361 0,06172518 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03102361 0,06167183 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03102361 0,06161857 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03102361 0,06156541 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03102361 0,06151233 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03102361 0,06145935 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03102361 0,06140646 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03102361 0,06135366 ! male genitalia development GO:0030539 13 11 0,000 0,03102361 0,06130095 ! cholesterol efflux GO:0033344 19 11 0,000 0,03102361 0,06124833 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03102361 0,0611958 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03102361 0,06114337 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03102361 0,06109102 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03102361 0,06103876 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03102361 0,06098659 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03102361 0,06093451 ! defense response to fungus GO:0050832 12 11 0,000 0,03102361 0,06088252 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03102361 0,06083061 ! lysogeny GO:0030069 18 11 0,000 0,03102361 0,0607788 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03102361 0,06072707 ! acrosome reaction GO:0007340 13 11 0,000 0,03102361 0,06067543 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03102361 0,06062388 ! extracellular structure organization GO:0043062 156 99 1,000 0,03261037 0,06367051 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,03261037 0,06361651 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,03321611 0,06474327 ! lactation GO:0007595 20 12 0,000 0,03379671 0,06581917 ! reproductive cellular process GO:0048610 14 12 0,000 0,03379671 0,06576348 ! tRNA modification GO:0006400 14 12 0,000 0,03379671 0,06570789 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03379671 0,0656524 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03379671 0,06559699 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03379671 0,06554168 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03379671 0,06548647 ! non-recombinational repair GO:0000726 19 12 0,000 0,03379671 0,06543134 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03379671 0,06537631 ! peroxisomal transport GO:0043574 21 12 0,000 0,03379671 0,06532138 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03379671 0,06526653 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03379671 0,06521178 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03379671 0,06515711 ! heart looping GO:0001947 15 12 0,000 0,03379671 0,06510254 ! palate development GO:0060021 15 12 0,000 0,03379671 0,06504806 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03379671 0,06499368 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03379671 0,06493938 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03379671 0,06488517 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03379671 0,06483106 ! arginine metabolic process GO:0006525 13 12 0,000 0,03379671 0,06477703 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03379671 0,0647231 ! methionine metabolic process GO:0006555 13 12 0,000 0,03379671 0,06466925 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03379671 0,06461549 ! Golgi organization GO:0007030 18 12 0,000 0,03379671 0,06456182 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03379671 0,06450825 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03379671 0,06445476 ! monoamine transport GO:0015844 13 12 0,000 0,03379671 0,06440136 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03379671 0,06434804 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03379671 0,06429482 ! L-amino acid transport GO:0015807 20 12 0,000 0,03379671 0,06424168 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03379671 0,06418864 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03379671 0,06413567 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03379671 0,0640828 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03379671 0,06403001 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03379671 0,06397731 ! cerebellum development GO:0021549 13 12 0,000 0,03379671 0,0639247 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03379671 0,06387218 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03379671 0,06381973 ! histone acetylation GO:0016573 23 12 0,000 0,03379671 0,06376738 ! histone methylation GO:0016571 15 12 0,000 0,03379671 0,06371511 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03379671 0,06366293 ! gland morphogenesis GO:0022612 23 12 0,000 0,03379671 0,06361083 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03379671 0,06355882 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,03379671 0,06350689 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03379671 0,06345505 ! response to gamma radiation GO:0010332 20 12 0,000 0,03379671 0,06340329 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03379671 0,06335162 ! intestinal absorption GO:0050892 19 12 0,000 0,03379671 0,06330003 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03379671 0,06324852 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03379671 0,0631971 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03379671 0,06314577 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03379671 0,06309451 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03379671 0,06304334 ! microspike assembly GO:0030035 23 12 0,000 0,03379671 0,06299225 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03379671 0,06294124 ! response to cold GO:0009409 14 12 0,000 0,03379671 0,06289032 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,03656203 0,06798114 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,03656203 0,06792623 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,03656203 0,06787141 ! cGMP metabolic process GO:0046068 16 13 0,000 0,03656203 0,06781667 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,03656203 0,06776203 ! water transport GO:0006833 17 13 0,000 0,03656203 0,06770747 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,03656203 0,067653 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,03656203 0,06759861 ! lipid localization GO:0010876 24 13 0,000 0,03656203 0,06754432 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,03656203 0,06749011 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,03656203 0,06743599 ! organelle fusion GO:0048284 28 13 0,000 0,03656203 0,06738195 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,03656203 0,067328 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,03656203 0,06727414 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,03656203 0,06722036 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,03656203 0,06716667 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,03656203 0,06711307 ! response to hexose stimulus GO:0009746 19 13 0,000 0,03656203 0,06705955 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,03656203 0,06700612 ! glutamate metabolic process GO:0006536 18 13 0,000 0,03656203 0,06695277 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,03656203 0,0668995 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,03656203 0,06684632 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,03656203 0,06679323 ! NAD metabolic process GO:0019674 21 13 0,000 0,03656203 0,06674022 ! exocrine system development GO:0035272 27 13 0,000 0,03656203 0,06668729 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,03656203 0,06663445 ! bone mineralization GO:0030282 15 13 0,000 0,03656203 0,06658169 ! regulation of exocytosis GO:0017157 17 13 0,000 0,03656203 0,06652902 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,03656203 0,06647642 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,03656203 0,06642391 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,03656203 0,06637149 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,03656203 0,06631915 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,03656203 0,06626688 ! genitalia development GO:0048806 15 13 0,000 0,03656203 0,06621471 ! regulation of cellular pH GO:0030641 20 13 0,000 0,03656203 0,06616261 ! cellular pigmentation GO:0033059 24 13 0,000 0,03656203 0,06611059 ! tissue regeneration GO:0042246 21 13 0,000 0,03656203 0,06605866 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,03656203 0,06600681 ! cofactor transport GO:0051181 19 13 0,000 0,03656203 0,06595504 ! NADP metabolic process GO:0006739 18 13 0,000 0,03656203 0,06590335 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,03656203 0,06585174 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,03656203 0,06580022 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03656203 0,06574877 ! gas transport GO:0015669 18 13 0,000 0,03656203 0,0656974 ! heme biosynthetic process GO:0006783 20 13 0,000 0,03656203 0,06564612 ! regulation of axon extension GO:0030516 23 13 0,000 0,03656203 0,06559491 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,03656203 0,06554379 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,03656203 0,06549274 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,03656203 0,06544177 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,03656203 0,06539088 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,03656203 0,06534007 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,03656203 0,06528934 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,0393196 0,0701591 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,0393196 0,07010471 ! superoxide anion generation GO:0042554 18 14 0,000 0,0393196 0,07005041 ! neuron maturation GO:0042551 21 14 0,000 0,0393196 0,06999619 ! regulation of S phase GO:0033261 18 14 0,000 0,0393196 0,06994205 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,0393196 0,069888 ! myotube differentiation GO:0014902 21 14 0,000 0,0393196 0,06983403 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,0393196 0,06978015 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,0393196 0,06972635 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,0393196 0,06967263 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,0393196 0,069619 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,0393196 0,06956544 ! gene silencing by RNA GO:0031047 20 14 0,000 0,0393196 0,06951197 ! response to cAMP GO:0051591 19 14 0,000 0,0393196 0,06945858 ! limbic system development GO:0021761 25 14 0,000 0,0393196 0,06940528 ! startle response GO:0001964 21 14 0,000 0,0393196 0,06935205 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,0393196 0,06929891 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,0393196 0,06924585 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,0393196 0,06919287 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,0393196 0,06913997 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,0393196 0,06908715 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,0393196 0,06903441 ! glycine metabolic process GO:0006544 22 14 0,000 0,0393196 0,06898175 ! pituitary gland development GO:0021983 23 14 0,000 0,0393196 0,06892917 ! cellular response to starvation GO:0009267 21 14 0,000 0,0393196 0,06887668 ! lysosomal transport GO:0007041 20 14 0,000 0,0393196 0,06882426 ! regulation of heart rate GO:0002027 23 14 0,000 0,0393196 0,06877192 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,0393196 0,06871966 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,0393196 0,06866748 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,0393196 0,06861538 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,0393196 0,06856336 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,0393196 0,06851142 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,0393196 0,06845956 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,0393196 0,06840777 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,0393196 0,06835607 ! axon cargo transport GO:0008088 27 14 0,000 0,0393196 0,06830444 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,0393196 0,06825289 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,0393196 0,06820141 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,0393196 0,06815002 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,0393196 0,0680987 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0393196 0,06804746 ! mRNA splice site selection GO:0006376 26 14 0,000 0,0393196 0,0679963 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,0393196 0,06794521 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,0393196 0,0678942 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,0393196 0,06784327 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,0393196 0,06779241 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,0393196 0,06774163 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,0393196 0,06769092 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,0393196 0,0676403 ! muscle maintenance GO:0046716 19 14 0,000 0,0393196 0,06758974 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,0393196 0,06753926 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,0393196 0,06748886 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,0393196 0,06743853 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,0393196 0,06738828 ! cell killing GO:0001906 20 14 0,000 0,0393196 0,06733811 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,0393196 0,067288 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,0393196 0,06723797 ! cilium assembly GO:0042384 20 14 0,000 0,0393196 0,06718802 ! peptide hormone secretion GO:0030072 23 14 0,000 0,0393196 0,06713814 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,04206943 0,07178018 ! positive regulation of cell size GO:0045793 20 15 0,000 0,04206943 0,07172697 ! metencephalon development GO:0022037 19 15 0,000 0,04206943 0,07167384 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,04206943 0,07162079 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,04206943 0,07156781 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,04206943 0,07151492 ! skin development GO:0043588 25 15 0,000 0,04206943 0,0714621 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,04206943 0,07140936 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,04206943 0,0713567 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,04206943 0,07130411 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,04206943 0,07125161 ! bile acid metabolic process GO:0008206 22 15 0,000 0,04206943 0,07119918 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,04206943 0,07114683 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,04206943 0,07109455 ! adult walking behavior GO:0007628 25 15 0,000 0,04206943 0,07104235 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,04206943 0,07099023 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,04206943 0,07093818 ! myoblast differentiation GO:0045445 27 15 0,000 0,04206943 0,07088621 ! centrosome cycle GO:0007098 16 15 0,000 0,04206943 0,07083432 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,04206943 0,0707825 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,04206943 0,07073076 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,04206943 0,0706791 ! cerebral cortex development GO:0021987 29 15 0,000 0,04206943 0,07062751 ! response to osmotic stress GO:0006970 22 15 0,000 0,04206943 0,07057599 ! vesicle coating GO:0006901 25 15 0,000 0,04206943 0,07052455 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,04206943 0,07047318 ! DNA integration GO:0015074 22 15 0,000 0,04206943 0,07042189 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,04206943 0,07037068 ! peptide secretion GO:0002790 27 15 0,000 0,04206943 0,07031954 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,04206943 0,07026847 ! regulation of vasodilation GO:0042312 24 15 0,000 0,04206943 0,07021748 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,04206943 0,07016656 ! neuron recognition GO:0008038 22 15 0,000 0,04206943 0,07011571 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,04206943 0,07006494 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,04206943 0,07001424 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,04206943 0,06996362 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,04206943 0,06991307 ! biomineral formation GO:0031214 18 15 0,000 0,04206943 0,06986259 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,04206943 0,06981218 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,04206943 0,06976185 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,04206943 0,06971159 ! dopamine metabolic process GO:0042417 30 15 0,000 0,04206943 0,0696614 ! organic cation transport GO:0015695 19 15 0,000 0,04206943 0,06961128 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,04206943 0,06956124 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,04206943 0,06951127 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,04206943 0,06946137 ! defense response to virus GO:0051607 27 15 0,000 0,04206943 0,06941154 ! peptide hormone processing GO:0016486 19 15 0,000 0,04206943 0,06936178 ! protein secretion GO:0009306 27 16 0,000 0,04481154 0,07382991 ! hormone secretion GO:0046879 25 16 0,000 0,04481154 0,07377706 ! bone remodeling GO:0046849 24 16 0,000 0,04481154 0,07372428 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04481154 0,07367159 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,04481154 0,07361896 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04481154 0,07356642 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04481154 0,07351394 ! glial cell development GO:0021782 24 16 0,000 0,04481154 0,07346155 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04481154 0,07340922 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04481154 0,07335697 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04481154 0,0733048 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04481154 0,0732527 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04481154 0,07320067 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04481154 0,07314872 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04481154 0,07309684 ! fructose metabolic process GO:0006000 20 16 0,000 0,04481154 0,07304504 ! regulation of protein binding GO:0043393 27 16 0,000 0,04481154 0,07299331 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04481154 0,07294165 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04481154 0,07289006 ! protein export from nucleus GO:0006611 24 16 0,000 0,04481154 0,07283855 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04481154 0,07278711 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04481154 0,07273574 ! DNA replication initiation GO:0006270 25 16 0,000 0,04481154 0,07268445 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04481154 0,07263323 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04481154 0,07258208 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04481154 0,072531 ! diencephalon development GO:0021536 25 16 0,000 0,04481154 0,07247999 ! oogenesis GO:0048477 23 16 0,000 0,04481154 0,07242906 ! neural crest cell migration GO:0001755 24 16 0,000 0,04481154 0,07237819 ! G1 phase GO:0051318 27 16 0,000 0,04481154 0,0723274 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04481154 0,07227668 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04481154 0,07222603 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04481154 0,07217545 ! steroid catabolic process GO:0006706 22 16 0,000 0,04481154 0,07212495 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04481154 0,07207451 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,04481154 0,07202414 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04481154 0,07197385 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04481154 0,07192362 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04481154 0,07187346 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04481154 0,07182338 ! nerve development GO:0021675 18 16 0,000 0,04481154 0,07177336 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04481154 0,07172342 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04481154 0,07167354 ! negative regulation of translation GO:0017148 22 16 0,000 0,04481154 0,07162373 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,04754597 0,07594147 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,04754597 0,07588877 ! negative regulation of defense response GO:0031348 19 17 0,000 0,04754597 0,07583614 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,04754597 0,07578359 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,04754597 0,07573111 ! glycerol metabolic process GO:0006071 20 17 0,000 0,04754597 0,0756787 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,04754597 0,07562636 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,04754597 0,0755741 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,04754597 0,07552191 ! signal complex assembly GO:0007172 29 17 0,000 0,04754597 0,07546979 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,04754597 0,07541774 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,04754597 0,07536576 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,04754597 0,07531386 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,04754597 0,07526202 ! memory GO:0007613 25 17 0,000 0,04754597 0,07521026 ! keratinization GO:0031424 17 17 0,000 0,04754597 0,07515857 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,04754597 0,07510695 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,04754597 0,0750554 ! retinoid metabolic process GO:0001523 22 17 0,000 0,04754597 0,07500392 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,04754597 0,07495252 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,04754597 0,07490118 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,04754597 0,07484991 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,04754597 0,07479871 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,04754597 0,07474759 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,04754597 0,07469653 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,04754597 0,07464554 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,04754597 0,07459462 ! membrane budding GO:0006900 29 17 0,000 0,04754597 0,07454378 ! heme metabolic process GO:0042168 27 17 0,000 0,04754597 0,074493 ! actin filament bundle formation GO:0051017 26 17 0,000 0,04754597 0,07444229 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,04754597 0,07439165 ! body fluid secretion GO:0007589 27 17 0,000 0,04754597 0,07434107 ! stem cell differentiation GO:0048863 36 17 0,000 0,04754597 0,07429057 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,04754597 0,07424014 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,04754597 0,07418977 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,04754597 0,07413947 ! sensory perception of pain GO:0019233 23 17 0,000 0,04754597 0,07408924 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,04754597 0,07403908 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,04754597 0,07398898 ! synaptogenesis GO:0007416 24 17 0,000 0,04754597 0,07393896 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,04754597 0,073889 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,04754597 0,07383911 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,04754597 0,07378928 ! cell-cell junction organization GO:0045216 25 17 0,000 0,04754597 0,07373953 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,04754597 0,07368984 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,04754597 0,07364022 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,04754597 0,07359066 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,04754597 0,07354117 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,04754597 0,07349175 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,05027272 0,0776543 ! positive regulation of translation GO:0045727 28 18 0,000 0,05027272 0,07760218 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,05027272 0,07755013 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,05027272 0,07749815 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,05027272 0,07744625 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,05027272 0,07739441 ! cAMP metabolic process GO:0046058 33 18 0,000 0,05027272 0,07734264 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,05027272 0,07729094 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,05027272 0,07723931 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,05027272 0,07718775 ! axis specification GO:0009798 26 18 0,000 0,05027272 0,07713626 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,05027272 0,07708483 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,05027272 0,07703348 ! pancreas development GO:0031016 26 18 0,000 0,05027272 0,07698219 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,05027272 0,07693097 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,05027272 0,07687982 ! glutamine metabolic process GO:0006541 23 18 0,000 0,05027272 0,07682874 ! response to retinoic acid GO:0032526 25 18 0,000 0,05027272 0,07677772 ! pigmentation during development GO:0048066 31 18 0,000 0,05027272 0,07672677 ! central nervous system neuron development GO:0021954 30 18 0,000 0,05027272 0,07667589 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,05027272 0,07662508 ! fucose metabolic process GO:0006004 26 18 0,000 0,05027272 0,07657434 ! response to fungus GO:0009620 19 18 0,000 0,05027272 0,07652366 ! peptide cross-linking GO:0018149 31 18 0,000 0,05027272 0,07647305 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,05027272 0,0764225 ! heart process GO:0003015 27 18 0,000 0,05027272 0,07637203 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,05027272 0,07632161 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,05027272 0,07627127 ! visual learning GO:0008542 35 18 0,000 0,05027272 0,07622099 ! somitogenesis GO:0001756 24 18 0,000 0,05027272 0,07617078 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,05027272 0,07612064 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,05027272 0,07607056 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,05027272 0,07602054 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,05027272 0,0759706 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,05027272 0,07592071 ! vitamin transport GO:0051180 24 18 0,000 0,05027272 0,0758709 ! hormone transport GO:0009914 27 18 0,000 0,05027272 0,07582115 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,05027272 0,07577146 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,05027272 0,07572184 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,05027272 0,07567228 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,05027272 0,07562279 ! cell-cell recognition GO:0009988 20 18 0,000 0,05027272 0,07557336 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,05027272 0,075524 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,05027272 0,0754747 ! regulation of glucose import GO:0046324 21 18 0,000 0,05027272 0,07542547 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,05027272 0,0753763 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,05027272 0,0753272 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,05027272 0,07527816 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,05299182 0,0792981 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,05299182 0,07924654 ! positive regulation of ossification GO:0045778 30 19 0,000 0,05299182 0,07919505 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,05299182 0,07914362 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,05299182 0,07909226 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,05299182 0,07904097 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,05299182 0,07898975 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,05299182 0,07893859 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,05299182 0,07888749 ! regeneration GO:0031099 32 19 0,000 0,05299182 0,07883647 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,05299182 0,07878551 ! response to alkaloid GO:0043279 32 19 0,000 0,05299182 0,07873461 ! sensory perception of taste GO:0050909 23 19 0,000 0,05299182 0,07868378 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,05299182 0,07863302 ! smooth muscle contraction GO:0006939 36 19 0,000 0,05299182 0,07858232 ! peroxisome organization GO:0007031 29 19 0,000 0,05299182 0,07853169 ! digestive system process GO:0022600 30 19 0,000 0,05299182 0,07848112 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,05299182 0,07843062 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,05299182 0,07838018 ! response to vitamin A GO:0033189 26 19 0,000 0,05299182 0,07832981 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,05299182 0,0782795 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,05299182 0,07822925 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,05299182 0,07817907 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,05299182 0,07812896 ! response to starvation GO:0042594 30 19 0,000 0,05299182 0,07807891 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,05299182 0,07802892 ! plasma membrane fusion GO:0045026 23 19 0,000 0,05299182 0,077979 ! cytolysis GO:0019835 20 19 0,000 0,05299182 0,07792914 ! renal system process GO:0003014 35 19 0,000 0,05299182 0,07787935 ! vasodilation GO:0042311 33 19 0,000 0,05299182 0,07782961 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,05299182 0,07777995 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,05299182 0,07773034 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,05299182 0,0776808 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,05299182 0,07763132 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,05299182 0,07758191 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,05299182 0,07753256 ! sarcomere organization GO:0045214 23 19 0,000 0,05299182 0,07748327 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,05299182 0,07743404 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,05299182 0,07738487 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,05299182 0,07733577 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,05299182 0,07728673 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,05299182 0,07723775 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,05299182 0,07718884 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,05299182 0,07713999 ! protein stabilization GO:0050821 26 19 0,000 0,05299182 0,07709119 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,05570329 0,08098455 ! iron ion transport GO:0006826 37 20 0,000 0,05570329 0,08093339 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,05570329 0,0808823 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,05570329 0,08083127 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,05570329 0,0807803 ! response to vitamin GO:0033273 29 20 0,000 0,05570329 0,0807294 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,05570329 0,08067856 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,05570329 0,08062779 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,05570329 0,08057708 ! spinal cord development GO:0021510 31 20 0,000 0,05570329 0,08052644 ! response to ethanol GO:0045471 37 20 0,000 0,05570329 0,08047585 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,05570329 0,08042534 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,05570329 0,08037488 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,05570329 0,08032449 ! chromosome condensation GO:0030261 31 20 0,000 0,05570329 0,08027416 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,05570329 0,08022389 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,05570329 0,08017369 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,05570329 0,08012355 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,05570329 0,08007347 ! pallium development GO:0021543 38 20 0,000 0,05570329 0,08002346 ! DNA modification GO:0006304 28 20 0,000 0,05570329 0,07997351 ! collagen fibril organization GO:0030199 45 20 0,000 0,05570329 0,07992362 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,05570329 0,07987379 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,05570329 0,07982402 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,05570329 0,07977432 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,05570329 0,07972468 ! collagen catabolic process GO:0030574 25 20 0,000 0,05570329 0,0796751 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,05570329 0,07962558 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,05570329 0,07957612 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,05570329 0,07952673 ! alditol metabolic process GO:0019400 24 20 0,000 0,05570329 0,07947739 ! actin filament-based movement GO:0030048 34 20 0,000 0,05570329 0,07942812 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,05840715 0,083232 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,05840715 0,08318046 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,05840715 0,08312899 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,05840715 0,08307758 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,05840715 0,08302623 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,05840715 0,08297495 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,05840715 0,08292373 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,05840715 0,08287257 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,05840715 0,08282148 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,05840715 0,08277045 GO:0034105|positive regulation of tissue remodeling, ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,05840715 0,08271948 ! protein amino acid acylation GO:0043543 37 21 0,000 0,05840715 0,08266858 ! vesicle docking GO:0048278 27 21 0,000 0,05840715 0,08261774 ! phototransduction GO:0007602 25 21 0,000 0,05840715 0,08256696 ! visual behavior GO:0007632 39 21 0,000 0,05840715 0,08251624 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,05840715 0,08246559 ! ovarian follicle development GO:0001541 30 21 0,000 0,05840715 0,08241499 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,05840715 0,08236446 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,05840715 0,082314 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,05840715 0,08226359 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,05840715 0,08221324 ! cell aging GO:0007569 32 21 0,000 0,05840715 0,08216296 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,05840715 0,08211274 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,05840715 0,08206258 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,05840715 0,08201248 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,05840715 0,08196244 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,05840715 0,08191246 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,05840715 0,08186255 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,05840715 0,08181269 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,05840715 0,0817629 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,05840715 0,08171316 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,05840715 0,08166349 ! fatty acid transport GO:0015908 30 21 0,000 0,05840715 0,08161388 ! immunoglobulin production GO:0002377 33 21 0,000 0,05840715 0,08156432 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,05840715 0,08151483 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,05840715 0,0814654 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,05840715 0,08141602 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,05840715 0,08136671 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,05840715 0,08131746 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,05840715 0,08126826 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,05840715 0,08121913 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,05840715 0,08117006 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,05840715 0,08112104 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,05840715 0,08107208 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,05840715 0,08102319 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,05840715 0,08097435 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,05840715 0,08092557 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,05840715 0,08087685 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,05840715 0,08082818 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,06110342 0,08450864 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,06110342 0,08445786 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,06110342 0,08440713 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,06110342 0,08435647 ! viral genome replication GO:0019079 29 22 0,000 0,06110342 0,08430586 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,06110342 0,08425532 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,06110342 0,08420484 ! leukocyte adhesion GO:0007159 38 22 0,000 0,06110342 0,08415441 ! molting cycle process GO:0022404 40 22 0,000 0,06110342 0,08410405 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,06110342 0,08405375 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,06110342 0,08400351 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,06110342 0,08395333 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,06110342 0,08390321 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,06110342 0,08385315 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,06110342 0,08380314 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,06110342 0,0837532 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,06110342 0,08370332 ! lysosome organization GO:0007040 37 22 0,000 0,06110342 0,0836535 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,06110342 0,08360373 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,06110342 0,08355403 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,06110342 0,08350438 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,06110342 0,08345479 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,06110342 0,08340527 ! membrane depolarization GO:0051899 35 22 0,000 0,06110342 0,0833558 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,06110342 0,08330639 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,06110342 0,08325703 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,06110342 0,08320774 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,06110342 0,0831585 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,06110342 0,08310933 ! blastocyst development GO:0001824 37 22 0,000 0,06110342 0,08306021 ! neural tube closure GO:0001843 33 22 0,000 0,06110342 0,08301115 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,06110342 0,08296214 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06379213 0,08656159 ! neuron fate commitment GO:0048663 32 23 0,000 0,06379213 0,08651055 ! embryonic pattern specification GO:0009880 31 23 0,000 0,06379213 0,08645957 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06379213 0,08640866 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06379213 0,0863578 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,06379213 0,086307 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,06379213 0,08625626 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,06379213 0,08620558 ! vesicle targeting GO:0006903 32 23 0,000 0,06379213 0,08615496 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06379213 0,0861044 ! osteoblast differentiation GO:0001649 40 23 0,000 0,06379213 0,0860539 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06379213 0,08600346 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06379213 0,08595307 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06379213 0,08590275 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,06379213 0,08585249 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,06379213 0,08580228 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,06379213 0,08575213 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,06379213 0,08570204 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,06379213 0,08565201 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06379213 0,08560204 ! cell fate determination GO:0001709 45 23 0,000 0,06379213 0,08555213 ! pentose metabolic process GO:0019321 31 23 0,000 0,06379213 0,08550227 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,06379213 0,08545247 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06379213 0,08540273 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06379213 0,08535305 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06379213 0,08530343 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06379213 0,08525386 ! telomere organization GO:0032200 32 23 0,000 0,06379213 0,08520435 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,06379213 0,0851549 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06379213 0,08510551 ! regulation of amine transport GO:0051952 38 23 0,000 0,06379213 0,08505617 ! liver development GO:0001889 40 23 0,000 0,06379213 0,08500689 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,06647329 0,08852841 ! initiation of viral infection GO:0019059 42 24 0,000 0,06647329 0,08847718 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,06647329 0,08842601 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,06647329 0,0883749 ! superoxide metabolic process GO:0006801 32 24 0,000 0,06647329 0,08832384 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,06647329 0,08827285 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,06647329 0,08822191 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,06647329 0,08817103 ! sperm motility GO:0030317 27 24 0,000 0,06647329 0,08812021 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,06647329 0,08806945 ! vacuole organization GO:0007033 39 24 0,000 0,06647329 0,08801875 ! receptor metabolic process GO:0043112 37 24 0,000 0,06647329 0,08796811 ! neural crest cell development GO:0014032 39 24 0,000 0,06647329 0,08791752 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,06647329 0,08786699 ! primary neural tube formation GO:0014020 35 24 0,000 0,06647329 0,08781652 ! negative regulation of cell development GO:0010721 56 24 0,000 0,06647329 0,08776611 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,06647329 0,08771576 ! base-excision repair GO:0006284 31 24 0,000 0,06647329 0,08766546 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,06647329 0,08761523 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,06647329 0,08756505 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,06647329 0,08751492 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,06647329 0,08746486 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,06647329 0,08741485 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,06914693 0,09087882 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,06914693 0,09082692 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,06914693 0,09077508 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,06914693 0,09072329 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,06914693 0,09067157 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,06914693 0,0906199 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,06914693 0,0905683 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,06914693 0,09051675 ! peptide transport GO:0015833 43 25 0,000 0,06914693 0,09046526 ! male gonad development GO:0008584 33 25 0,000 0,06914693 0,09041383 ! iron ion homeostasis GO:0055072 39 25 0,000 0,06914693 0,09036246 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,06914693 0,09031115 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,06914693 0,09025989 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,06914693 0,0902087 ! phospholipid transport GO:0015914 35 25 0,000 0,06914693 0,09015756 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,06914693 0,09010648 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,06914693 0,09005545 ! detection of light stimulus GO:0009583 30 25 0,000 0,06914693 0,09000449 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,06914693 0,08995358 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,06914693 0,08990273 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,07181306 0,0933164 ! translational initiation GO:0006413 43 26 0,000 0,07181306 0,09326371 ! regulation of pH GO:0006885 36 26 0,000 0,07181306 0,09321108 ! circadian rhythm GO:0007623 42 26 0,000 0,07181306 0,09315851 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,07181306 0,09310599 ! post-embryonic development GO:0009791 42 26 0,000 0,07181306 0,09305354 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,07181306 0,09300115 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,07181306 0,09294881 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,07181306 0,09289653 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,07181306 0,09284431 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,07181306 0,09279215 ! regulation of coagulation GO:0050818 39 26 0,000 0,07181306 0,09274005 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,07447171 0,09611949 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,07447171 0,09606558 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,07447171 0,09601173 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,07447171 0,09595794 ! membrane docking GO:0022406 39 27 0,000 0,07447171 0,09590421 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,07447171 0,09585054 ! catechol metabolic process GO:0009712 43 27 0,000 0,07447171 0,09579694 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,07447171 0,09574339 ! acute-phase response GO:0006953 42 27 0,000 0,07447171 0,0956899 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,07447171 0,09563647 ! myofibril assembly GO:0030239 36 27 0,000 0,07447171 0,0955831 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,07447171 0,09552979 ! response to ionizing radiation GO:0010212 47 27 0,000 0,07447171 0,09547655 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,07447171 0,09542336 ! natural killer cell activation GO:0030101 35 27 0,000 0,07447171 0,09537022 ! lipid oxidation GO:0034440 38 27 0,000 0,07447171 0,09531715 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,07447171 0,09526414 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,07447171 0,09521119 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,07447171 0,09515829 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,07447171 0,09510545 ! gene silencing GO:0016458 41 27 0,000 0,07447171 0,09505268 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,07712289 0,09838194 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,07712289 0,09832741 ! phenol metabolic process GO:0018958 44 28 0,000 0,07712289 0,09827293 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,07712289 0,09821852 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,07712289 0,09816416 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,07712289 0,09810987 ! cell junction assembly GO:0034329 56 28 0,000 0,07712289 0,09805564 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,07712289 0,09800146 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,07712289 0,09794735 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,07712289 0,09789329 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,07712289 0,0978393 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,07712289 0,09778536 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,07712289 0,09773149 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,07712289 0,09767767 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,07712289 0,09762391 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,07712289 0,09757021 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,07712289 0,09751657 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,07712289 0,09746299 ! mesoderm formation GO:0001707 46 28 0,000 0,07712289 0,09740947 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,07712289 0,09735601 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,07712289 0,0973026 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,07712289 0,09724926 ! BMP signaling pathway GO:0030509 40 28 0,000 0,07712289 0,09719597 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,07712289 0,09714274 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,07712289 0,09708957 ! neural tube formation GO:0001841 41 28 0,000 0,07712289 0,09703646 ! placenta development GO:0001890 37 28 0,000 0,07712289 0,0969834 ! regulation of B cell activation GO:0050864 42 28 0,000 0,07712289 0,09693041 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,07976663 0,10019839 ! regulation of innate immune response GO:0045088 38 29 0,000 0,07976663 0,1001437 ! ovulation cycle process GO:0022602 41 29 0,000 0,07976663 0,10008906 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,07976663 0,10003449 ! protein targeting to membrane GO:0006612 53 29 0,000 0,07976663 0,09997997 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,07976663 0,09992552 ! mismatch repair GO:0006298 34 29 0,000 0,07976663 0,09987112 ! muscle cell development GO:0055001 38 29 0,000 0,07976663 0,09981678 ! formation of primary germ layer GO:0001704 48 29 0,000 0,07976663 0,09976251 ! telencephalon development GO:0021537 52 29 0,000 0,07976663 0,09970829 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,07976663 0,09965413 ! eye morphogenesis GO:0048592 51 29 0,000 0,07976663 0,09960003 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,07976663 0,09954598 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,08240295 0,10278025 ! collagen metabolic process GO:0032963 40 30 0,000 0,08240295 0,10272454 ! organic anion transport GO:0015711 51 30 0,000 0,08240295 0,1026689 ! cholesterol transport GO:0030301 46 30 0,000 0,08240295 0,10261331 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,08240295 0,10255778 ! spliceosome assembly GO:0000245 49 30 0,000 0,08240295 0,10250232 ! spindle organization GO:0007051 37 30 0,000 0,08240295 0,10244691 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,08240295 0,10239156 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,08240295 0,10233628 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,08240295 0,10228105 ! ceramide metabolic process GO:0006672 43 30 0,000 0,08240295 0,10222588 ! ovulation cycle GO:0042698 43 30 0,000 0,08240295 0,10217077 ! hindbrain development GO:0030902 45 30 0,000 0,08240295 0,10211572 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,08240295 0,10206073 ! adult locomotory behavior GO:0008344 47 30 0,000 0,08240295 0,1020058 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,08240295 0,10195093 ! response to heat GO:0009408 41 30 0,000 0,08240295 0,10189612 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,08240295 0,10184137 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,08240295 0,10178667 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,08503187 0,10497761 ! negative regulation of secretion GO:0051048 49 31 0,000 0,08503187 0,10492129 ! glial cell differentiation GO:0010001 55 31 0,000 0,08503187 0,10486504 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,08503187 0,10480884 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,08503187 0,1047527 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,08503187 0,10469662 ! odontogenesis GO:0042476 50 31 0,000 0,08503187 0,1046406 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,08503187 0,10458465 ! segmentation GO:0035282 41 31 0,000 0,08503187 0,10452875 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,08503187 0,10447291 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,08503187 0,10441713 ! metanephros development GO:0001656 58 31 0,000 0,08503187 0,10436141 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,08503187 0,10430575 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,08503187 0,10425015 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,08503187 0,10419461 ! cell fate specification GO:0001708 37 31 0,000 0,08503187 0,10413913 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,08503187 0,10408371 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,08503187 0,10402835 ! RNA modification GO:0009451 40 31 0,000 0,08503187 0,10397304 ! regulation of muscle development GO:0048634 48 32 0,000 0,0876534 0,10712158 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,0876534 0,1070647 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,0876534 0,10700787 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,0876534 0,1069511 ! meiosis I GO:0007127 52 32 0,000 0,0876534 0,10689439 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,0876534 0,10683774 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,0876534 0,10678116 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,0876534 0,10672463 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,0876534 0,10666816 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,0876534 0,10661175 ! cytokine production GO:0001816 44 32 0,000 0,0876534 0,1065554 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,0876534 0,10649911 ! vesicle localization GO:0051648 47 32 0,000 0,0876534 0,10644288 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,09026757 0,10955959 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,09026757 0,1095018 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,09026757 0,10944408 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,09026757 0,10938642 ! sister chromatid segregation GO:0000819 46 33 0,000 0,09026757 0,10932882 ! ear morphogenesis GO:0042471 42 33 0,000 0,09026757 0,10927127 ! actomyosin structure organization GO:0031032 43 33 0,000 0,09026757 0,10921379 ! cell junction organization GO:0034330 63 33 0,000 0,09026757 0,10915637 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,09026757 0,10909901 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,09026757 0,10904171 ! nucleus organization GO:0006997 49 33 0,000 0,09026757 0,10898447 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,09026757 0,10892729 ! female gonad development GO:0008585 49 33 0,000 0,09026757 0,10887017 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,09026757 0,10881311 ! positive regulation of cell development GO:0010720 54 33 0,000 0,09026757 0,10875611 ! lipid homeostasis GO:0055088 55 33 0,000 0,09026757 0,10869917 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,09026757 0,10864229 ! regulation of proteolysis GO:0030162 50 33 0,000 0,09026757 0,10858547 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,09026757 0,10852871 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,09026757 0,10847201 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,09026757 0,10841536 ! mRNA catabolic process GO:0006402 48 34 0,000 0,09287441 0,11148807 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,09287441 0,11142991 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,09287441 0,11137181 ! feeding behavior GO:0007631 45 34 0,000 0,09287441 0,11131378 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,09287441 0,1112558 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,09287441 0,11119788 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,09287441 0,11114003 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,09287441 0,11108223 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,09287441 0,1110245 ! neuron migration GO:0001764 46 34 0,000 0,09287441 0,11096682 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,09287441 0,11090921 ! female gamete generation GO:0007292 43 34 0,000 0,09287441 0,11085165 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,09287441 0,11079416 ! aerobic respiration GO:0009060 47 34 0,000 0,09287441 0,11073672 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,09287441 0,11067934 ! embryonic organ development GO:0048568 45 34 0,000 0,09287441 0,11062203 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,09287441 0,11056477 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,09547392 0,11360063 ! Notch signaling pathway GO:0007219 56 35 0,000 0,09547392 0,11354189 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,09547392 0,11348321 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,09547392 0,11342459 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,09547392 0,11336604 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,09547392 0,11330754 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,09547392 0,1132491 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,09547392 0,11319073 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,09547392 0,11313241 ! glycogen metabolic process GO:0005977 48 35 0,000 0,09547392 0,11307416 ! pigment metabolic process GO:0042440 61 35 0,000 0,09547392 0,11301596 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,09547392 0,11295783 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,09806613 0,11596509 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,09806613 0,1159055 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,09806613 0,11584597 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,09806613 0,1157865 ! negative regulation of binding GO:0051100 58 36 0,000 0,09806613 0,11572709 ! organic ether metabolic process GO:0018904 46 36 0,000 0,09806613 0,11566774 ! neural tube development GO:0021915 50 36 0,000 0,09806613 0,11560846 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,09806613 0,11554923 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,09806613 0,11549007 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,09806613 0,11543096 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,09806613 0,11537192 ! glucan metabolic process GO:0044042 49 36 0,000 0,09806613 0,11531293 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,10065106 0,118292 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,10065106 0,11823158 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,10065106 0,11817123 ! learning GO:0007612 67 37 0,000 0,10065106 0,11811094 ! ion transmembrane transport GO:0034220 56 37 0,000 0,10065106 0,11805071 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,10065106 0,11799054 ! regulation of protein secretion GO:0050708 51 37 0,000 0,10065106 0,11793043 ! amino acid activation GO:0043038 52 37 0,000 0,10065106 0,11787039 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,10065106 0,1178104 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,10322873 0,12076606 ! gliogenesis GO:0042063 71 38 0,000 0,10322873 0,12070467 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,10322873 0,12064333 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,10322873 0,12058206 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,10322873 0,12052085 ! phagocytosis GO:0006909 60 38 0,000 0,10322873 0,1204597 ! mesenchymal cell development GO:0014031 64 38 0,000 0,10322873 0,12039862 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,10322873 0,1203376 ! maintenance of location in cell GO:0051651 69 38 0,000 0,10322873 0,12027663 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,10579916 0,12320915 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,10579916 0,12314679 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,10579916 0,1230845 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,10579916 0,12302228 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,10579916 0,12296011 ! male sex differentiation GO:0046661 53 39 0,000 0,10579916 0,12289801 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,10579916 0,12283597 ! chromatin remodeling GO:0006338 68 39 0,000 0,10579916 0,122774 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,10579916 0,12271208 ! JNK cascade GO:0007254 54 39 0,000 0,10579916 0,12265023 ! developmental growth GO:0048589 62 39 0,000 0,10579916 0,12258845 ! cell growth GO:0016049 61 39 0,000 0,10579916 0,12252672 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,10836237 0,12543203 ! response to calcium ion GO:0051592 58 40 0,000 0,10836237 0,12536894 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,10836237 0,1253059 ! regulation of tube size GO:0035150 60 40 0,000 0,10836237 0,12524294 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,10836237 0,12518003 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,10836237 0,12511719 ! peptide metabolic process GO:0006518 56 40 0,000 0,10836237 0,12505441 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,10836237 0,1249917 ! inner ear development GO:0048839 57 40 0,000 0,10836237 0,12492904 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,10836237 0,12486645 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,10836237 0,12480393 ! double-strand break repair GO:0006302 67 40 0,000 0,10836237 0,12474146 ! B cell differentiation GO:0030183 62 40 0,000 0,10836237 0,12467906 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,10836237 0,12461672 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,10836237 0,12455444 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,10836237 0,12449223 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,11091837 0,12736508 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,11091837 0,12730153 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,11091837 0,12723803 ! glucose transport GO:0015758 52 41 0,000 0,11091837 0,12717461 ! endosome transport GO:0016197 71 41 0,000 0,11091837 0,12711124 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,11091837 0,12704794 ! biopolymer methylation GO:0043414 62 41 0,000 0,11091837 0,1269847 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,11091837 0,12692152 ! mitochondrial transport GO:0006839 60 42 0,000 0,1134672 0,12977353 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,1134672 0,12970903 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,1134672 0,12964459 ! cellular component disassembly GO:0022411 64 42 0,000 0,1134672 0,12958022 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,1134672 0,12951591 ! hexose transport GO:0008645 54 42 0,000 0,1134672 0,12945167 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,1134672 0,12938749 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,1134672 0,12932337 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,1134672 0,12925932 ! excretion GO:0007588 63 42 0,000 0,1134672 0,12919533 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,1134672 0,1291314 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,1134672 0,12906754 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,1134672 0,12900374 ! leukocyte migration GO:0050900 60 43 0,000 0,11600887 0,13182826 ! neuromuscular process GO:0050905 79 43 0,000 0,11600887 0,13176316 ! activation of caspase activity GO:0006919 65 43 0,000 0,11600887 0,13169812 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,11600887 0,13163315 ! tRNA processing GO:0008033 49 43 0,000 0,11600887 0,13156824 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,11600887 0,1315034 ! vesicle organization GO:0016050 79 43 0,000 0,11600887 0,13143862 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,11600887 0,1313739 ! methylation GO:0032259 64 43 0,000 0,11600887 0,13130925 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,11854339 0,13411205 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,11854339 0,13404611 ! glycolysis GO:0006096 53 44 0,000 0,11854339 0,13398024 ! regulation of ion transport GO:0043269 57 44 0,000 0,11854339 0,13391444 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,11854339 0,1338487 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,11854339 0,13378302 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,11854339 0,13371741 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,11854339 0,13365186 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,11854339 0,13358638 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,11854339 0,13352096 ! RNA catabolic process GO:0006401 64 45 0,000 0,12107079 0,13630094 ! positive regulation of defense response GO:0031349 59 45 0,000 0,12107079 0,13623426 ! regulation of translational initiation GO:0006446 64 45 0,000 0,12107079 0,13616764 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,12107079 0,13610108 ! cell recognition GO:0008037 58 45 0,000 0,12107079 0,1360346 ! cell maturation GO:0048469 60 45 0,000 0,12107079 0,13596817 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,12359109 0,13873085 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,12359109 0,13866317 ! regulation of ossification GO:0030278 71 46 0,000 0,12359109 0,13859557 ! histone modification GO:0016570 68 46 0,000 0,12359109 0,13852802 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,12359109 0,13846055 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,12610431 0,14120735 ! viral infectious cycle GO:0019058 71 47 0,000 0,12610431 0,14113864 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,12610431 0,14106999 ! endocrine system development GO:0035270 83 47 0,000 0,12610431 0,14100141 ! covalent chromatin modification GO:0016569 75 47 0,000 0,12610431 0,1409329 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,12610431 0,14086445 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,12610431 0,14079607 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,12610431 0,14072776 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,12610431 0,14065951 ! chloride transport GO:0006821 67 48 0,000 0,12861046 0,14338539 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,12861046 0,14331592 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,12861046 0,14324652 ! response to temperature stimulus GO:0009266 62 48 0,000 0,12861046 0,14317718 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,12861046 0,14310791 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,12861046 0,14303871 ! gastrulation GO:0007369 73 48 0,000 0,12861046 0,14296958 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,12861046 0,14290051 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,12861046 0,14283151 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,12861046 0,14276258 ! regulation of endocytosis GO:0030100 63 48 0,000 0,12861046 0,14269371 ! nuclear export GO:0051168 69 48 0,000 0,12861046 0,14262491 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,12861046 0,14255617 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,13110957 0,14525627 ! sensory perception of smell GO:0007608 61 49 0,000 0,13110957 0,14518633 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,13110957 0,14511646 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,13110957 0,14504666 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,13110957 0,14497693 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,13110957 0,14490726 ! maintenance of location GO:0051235 84 49 0,000 0,13110957 0,14483766 ! regulation of actin filament length GO:0030832 72 50 0,000 0,13360165 0,14751983 ! ear development GO:0043583 72 50 0,000 0,13360165 0,14744904 ! membrane fusion GO:0006944 80 50 0,000 0,13360165 0,14737832 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,13360165 0,14730767 ! proton transport GO:0015992 75 50 0,000 0,13360165 0,14723709 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,13360165 0,14716657 ! positive regulation of secretion GO:0051047 71 51 0,000 0,13608674 0,14983221 ! hydrogen transport GO:0006818 77 51 0,000 0,13608674 0,14976052 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,13608674 0,1496889 ! adult behavior GO:0030534 80 51 0,000 0,13608674 0,14961735 ! transition metal ion transport GO:0000041 74 52 0,000 0,13856483 0,15226904 ! regulation of cellular component size GO:0032535 74 52 0,000 0,13856483 0,15219633 ! aging GO:0007568 79 52 0,000 0,13856483 0,15212368 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,13856483 0,1520511 ! establishment of organelle localization GO:0051656 85 52 0,000 0,13856483 0,15197859 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,14103596 0,15461521 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,14103596 0,15454154 ! kidney development GO:0001822 90 53 0,000 0,14103596 0,15446795 ! single fertilization GO:0007338 59 53 0,000 0,14103596 0,15439443 ! cell projection assembly GO:0030031 76 53 0,000 0,14103596 0,15432098 ! amino acid transport GO:0006865 84 54 0,000 0,14350014 0,15694261 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,14350014 0,15686802 ! regulation of mitosis GO:0007088 84 54 0,000 0,14350014 0,1567935 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,14350014 0,15671905 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,14350014 0,15664467 ! detection of external stimulus GO:0009581 66 54 0,000 0,14350014 0,15657036 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,14350014 0,15649612 ! mesoderm development GO:0007498 76 55 0,000 0,14595739 0,15910047 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,14595739 0,15902511 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,14595739 0,15894981 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,14840773 0,16154178 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,14840773 0,16146537 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,14840773 0,16138902 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,15085119 0,16396868 ! carbohydrate transport GO:0008643 74 57 0,000 0,15085119 0,16389123 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,15085119 0,16381385 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,15085119 0,16373654 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,15085119 0,16365931 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,15085119 0,16358214 ! camera-type eye development GO:0043010 88 57 0,000 0,15085119 0,16350506 ! secondary metabolic process GO:0019748 84 57 0,000 0,15085119 0,16342804 ! developmental maturation GO:0021700 75 57 0,000 0,15085119 0,1633511 ! gonad development GO:0008406 79 57 0,000 0,15085119 0,16327423 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,15328777 0,16583343 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,15328777 0,16575546 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,15328777 0,16567757 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,1557175 0,16822463 ! actin filament organization GO:0007015 95 59 0,000 0,1557175 0,16814566 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,1557175 0,16806675 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,1557175 0,16798792 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,15814039 0,17052176 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,15814039 0,17044185 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,15814039 0,17036202 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,15814039 0,17028226 ! regulation of heart contraction GO:0008016 91 60 0,000 0,15814039 0,17020258 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,15814039 0,17012297 ! fertilization GO:0009566 68 60 0,000 0,15814039 0,17004344 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,16055648 0,1725607 ! meiosis GO:0007126 96 61 0,000 0,16055648 0,1724801 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,16055648 0,17239958 ! urogenital system development GO:0001655 101 61 0,000 0,16055648 0,17231913 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,16055648 0,17223876 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,16055648 0,17215846 ! extracellular matrix organization GO:0030198 103 61 0,000 0,16055648 0,17207824 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,16055648 0,17199809 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,16055648 0,17191801 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,16055648 0,17183802 ! amine catabolic process GO:0009310 90 62 0,000 0,16296576 0,17433547 ! neurotransmitter transport GO:0006836 81 62 0,000 0,16296576 0,17425442 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,16296576 0,17417345 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,16296576 0,17409255 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,16296576 0,17401172 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,16296576 0,17393098 ! meiotic cell cycle GO:0051321 97 62 0,000 0,16296576 0,1738503 ! organelle localization GO:0051640 96 62 0,000 0,16296576 0,17376971 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,16536827 0,17624978 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,16536827 0,17616815 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,16776402 0,17863762 ! negative regulation of cell size GO:0045792 108 64 0,000 0,16776402 0,17855495 ! appendage morphogenesis GO:0035107 93 64 0,000 0,16776402 0,17847237 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,16776402 0,17838985 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,16776402 0,17830742 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,16776402 0,17822506 ! hexose catabolic process GO:0019320 82 64 0,000 0,16776402 0,17814278 ! reproductive structure development GO:0048608 90 65 0,000 0,17015303 0,18059621 ! appendage development GO:0048736 94 65 0,000 0,17015303 0,18051291 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,17015303 0,18042968 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,17015303 0,18034653 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,17015303 0,18026346 ! defense response to bacterium GO:0042742 73 65 0,000 0,17015303 0,18018047 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,17015303 0,18009755 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,17015303 0,18001471 ! activation of immune response GO:0002253 83 65 0,000 0,17015303 0,17993194 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,17253532 0,1823673 ! antigen processing and presentation GO:0019882 96 66 0,000 0,17253532 0,18228353 ! regulation of immune effector process GO:0002697 101 66 0,000 0,17253532 0,18219984 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,17491091 0,18462373 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,17491091 0,18453904 ! acute inflammatory response GO:0002526 92 68 0,000 0,17727982 0,18695258 ! learning or memory GO:0007611 123 68 0,000 0,17727982 0,1868669 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,17727982 0,1867813 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,17727982 0,18669578 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,17727982 0,18661033 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,17727982 0,18652497 ! rhythmic process GO:0048511 105 68 0,000 0,17727982 0,18643968 ! inorganic anion transport GO:0015698 93 68 0,000 0,17727982 0,18635447 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,17964205 0,18875136 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,17964205 0,18866517 ! response to drug GO:0042493 108 69 0,000 0,17964205 0,18857906 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,17964205 0,18849303 ! response to metal ion GO:0010038 103 70 0,000 0,18199764 0,1908776 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,18199764 0,1907906 ! humoral immune response GO:0006959 86 70 0,000 0,18199764 0,19070368 ! eye development GO:0001654 111 70 0,000 0,18199764 0,19061684 ! amine transport GO:0015837 101 70 0,000 0,18199764 0,19053008 ! muscle cell differentiation GO:0042692 104 71 0,000 0,18434661 0,19290136 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,18434661 0,19281364 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,18434661 0,192726 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,18434661 0,19263843 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,18434661 0,19255095 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,18434661 0,19246355 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,18668896 0,1948206 ! regulation of blood pressure GO:0008217 107 73 0,000 0,18902471 0,19716864 ! tube morphogenesis GO:0035239 118 73 0,000 0,18902471 0,19707926 ! mitochondrion organization GO:0007005 104 73 0,000 0,18902471 0,19698996 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,18902471 0,19690074 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,18902471 0,19681161 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,1913539 0,19914659 ! digestion GO:0007586 97 74 0,000 0,1913539 0,19905652 ! protein import into nucleus GO:0006606 118 74 0,000 0,1913539 0,19896653 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,1913539 0,19887662 ! blood coagulation GO:0007596 116 75 0,000 0,19367653 0,20119964 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,19367653 0,20110881 ! negative regulation of growth GO:0045926 123 75 0,000 0,19367653 0,20101806 ! response to nutrient GO:0007584 104 75 0,000 0,19367653 0,20092738 ! regulation of ligase activity GO:0051340 114 75 0,000 0,19367653 0,20083679 ! nuclear import GO:0051170 121 75 0,000 0,19367653 0,20074629 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,19367653 0,20065586 ! amine biosynthetic process GO:0009309 97 76 0,000 0,19599262 0,20296399 ! tRNA metabolic process GO:0006399 95 76 0,000 0,19599262 0,20287265 ! response to unfolded protein GO:0006986 99 76 0,000 0,19599262 0,20278138 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,19830219 0,2050787 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,19830219 0,20498653 ! sex differentiation GO:0007548 105 77 0,000 0,19830219 0,20489444 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,19830219 0,20480244 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,19830219 0,20471052 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,20060525 0,2069951 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,20060525 0,20690228 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,20060525 0,20680954 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,20290184 0,20908343 ! cellular respiration GO:0045333 107 79 0,000 0,20290184 0,2089898 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,20290184 0,20889625 ! T cell activation GO:0042110 134 79 0,000 0,20290184 0,20880279 ! regulation of lyase activity GO:0051339 133 79 0,000 0,20290184 0,2087094 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,20290184 0,2086161 ! chromatin assembly GO:0031497 102 80 0,000 0,20519195 0,21087645 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,20519195 0,21078227 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,20519195 0,21068817 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,20519195 0,21059415 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,20519195 0,21050022 ! forebrain development GO:0030900 131 80 0,000 0,20519195 0,21040637 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,20747562 0,21265327 ! hemostasis GO:0007599 125 81 0,000 0,20747562 0,21255854 ! mRNA transport GO:0051028 121 81 0,000 0,20747562 0,21246391 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,20747562 0,21236935 ! response to protein stimulus GO:0051789 111 81 0,000 0,20747562 0,21227488 ! regulation of neurological system process GO:0031644 122 81 0,000 0,20747562 0,21218049 ! vitamin metabolic process GO:0006766 103 81 0,000 0,20747562 0,21208619 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,20747562 0,21199197 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,20975286 0,21422361 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,21202369 0,21644673 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,21202369 0,2163507 ! regulation of defense response GO:0031347 117 84 0,000 0,21428812 0,21856438 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,21428812 0,21846749 ! sterol metabolic process GO:0016125 120 84 0,000 0,21428812 0,2183707 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,21654617 0,22057404 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,21654617 0,2204764 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,21879786 0,22267039 ! nucleosome organization GO:0034728 114 87 0,000 0,22104321 0,22485599 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,22104321 0,22475658 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,22104321 0,22465726 ! female pregnancy GO:0007565 130 87 0,000 0,22104321 0,22455803 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,22104321 0,22445889 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,22328224 0,22663245 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,22328224 0,22653248 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,22328224 0,2264326 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,22328224 0,22633281 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,22551495 0,22849533 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,22551495 0,22839471 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,22551495 0,22829419 ! leukocyte differentiation GO:0002521 143 90 0,000 0,22774138 0,23044662 ! hormone metabolic process GO:0042445 121 90 0,000 0,22774138 0,23034528 ! RNA localization GO:0006403 135 91 0,000 0,22996153 0,23248858 ! ATP metabolic process GO:0046034 137 91 0,000 0,22996153 0,23238644 ! response to virus GO:0009615 122 91 0,000 0,22996153 0,23228438 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,23217543 0,23441769 ! cell fate commitment GO:0045165 141 92 0,000 0,23217543 0,23431483 ! positive regulation of immune response GO:0050778 121 92 0,000 0,23217543 0,23421206 ! DNA recombination GO:0006310 146 92 0,000 0,23217543 0,23410938 ! sulfur metabolic process GO:0006790 118 92 0,000 0,23217543 0,23400679 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,2343831 0,23612839 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,2343831 0,23602501 ! response to oxidative stress GO:0006979 141 94 0,000 0,23658454 0,23813761 ! carboxylic acid transport GO:0046942 147 95 0,000 0,23877977 0,24024212 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,24096882 0,24233856 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,24096882 0,24223264 ! protein maturation GO:0051604 129 96 0,000 0,24096882 0,24212682 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,2431517 0,2442135 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,2431517 0,2441069 ! calcium ion transport GO:0006816 167 99 0,000 0,24749902 0,24836289 ! protein import GO:0017038 156 99 0,000 0,24749902 0,24825458 ! regulation of translation GO:0006417 151 100 0,000 0,2496635 0,2503165 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,2496635 0,25020743 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,2496635 0,25009845 ! divalent metal ion transport GO:0070838 171 100 0,000 0,2496635 0,24998957 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,2496635 0,24988078 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,2496635 0,24977209 ! protein localization in organelle GO:0033365 161 100 0,000 0,2496635 0,2496635