pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6896-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phospholipid dephosphorylation GO:0046839 12 5 3,000 1,676E-10 4,031E-07 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 4,72E-10 5,678E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 5,017E-10 4,024E-07 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 1,168E-09 7,029E-07 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 2,333E-09 1,122E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 5,879E-09 2,357E-06 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 6,972E-09 2,396E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 1,094E-08 3,289E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 2,361E-08 6,311E-06 ! endothelial cell migration GO:0043542 28 17 3,000 7,799E-08 1,877E-05 ! inositol metabolic process GO:0006020 28 17 3,000 7,799E-08 1,706E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 7,799E-08 1,564E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 2,87E-07 5,311E-05 GO:0010810|regulation of cell-substrate adhesion, ! lipid modification GO:0030258 97 57 4,000 2,959E-07 5,085E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 7,904E-07 1,268E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 8,766E-07 1,318E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 9,608E-07 1,36E-04 ! protein heterooligomerization GO:0051291 16 9 2,000 1,183E-06 1,582E-04 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 1,659E-06 2,101E-04 ! establishment of cell polarity GO:0030010 16 10 2,000 1,688E-06 2,03E-04 ! regulation of protein stability GO:0031647 73 37 3,000 2,085E-06 2,389E-04 ! regulation of cell adhesion GO:0030155 212 89 4,000 2,759E-06 3,018E-04 ! polyol metabolic process GO:0019751 66 41 3,000 3,174E-06 3,32E-04 ! negative regulation of cell migration GO:0030336 115 46 3,000 5,067E-06 5,08E-04 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 3,000 7,688E-06 7,399E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 9,446E-06 8,741E-04 ! RNA elongation GO:0006354 79 55 3,000 1,041E-05 9,28E-04 ! negative regulation of cell motion GO:0051271 134 55 3,000 1,041E-05 8,949E-04 ! positive regulation of cell migration GO:0030335 126 57 3,000 1,202E-05 9,97E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 1,475E-05 1,183E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,575E-05 1,223E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,908E-05 1,435E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,12E-05 1,546E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 3,555E-05 2,516E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 3,000 4,174E-05 2,869E-03 ! protein oligomerization GO:0051259 139 78 3,000 4,174E-05 2,789E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,927E-05 3,854E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 5,927E-05 3,753E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,927E-05 3,657E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 5,927E-05 3,565E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 6,71E-05 3,938E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 8,309E-05 4,76E-03 ! transcription initiation GO:0006352 153 94 3,000 8,662E-05 4,847E-03 ! male sex determination GO:0030238 15 6 1,000 8,877E-05 4,854E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,042E-04 5,571E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,042E-04 5,45E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,241E-04 6,352E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,241E-04 6,22E-03 GO:0043489|RNA stabilization, ! regulation of respiratory burst GO:0060263 11 7 1,000 1,241E-04 6,093E-03 ! cytokinesis GO:0000910 72 40 2,000 1,318E-04 6,341E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,526E-04 7,198E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,637E-04 7,576E-03 ! striated muscle contraction GO:0006941 77 43 2,000 1,637E-04 7,433E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,652E-04 7,36E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,652E-04 7,226E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,652E-04 7,097E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,652E-04 6,972E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,652E-04 6,852E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,652E-04 6,736E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,003E-04 8,034E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 2,003E-04 7,902E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 2,12E-04 8,228E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,12E-04 8,098E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 2,12E-04 7,971E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,12E-04 7,848E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 2,12E-04 7,73E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,12E-04 7,614E-03 ! motor axon guidance GO:0008045 16 9 1,000 2,12E-04 7,502E-03 ! lung alveolus development GO:0048286 26 10 1,000 2,646E-04 9,227E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 2,646E-04 9,095E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,646E-04 8,967E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,646E-04 8,843E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,646E-04 8,722E-03 ! localization within membrane GO:0051668 20 10 1,000 2,646E-04 8,604E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,229E-04 0,01035886 ! blood vessel remodeling GO:0001974 29 11 1,000 3,229E-04 0,01022256 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 3,229E-04 0,0100898 ! regulation of leukocyte migration GO:0002685 26 11 1,000 3,229E-04 9,96E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 3,229E-04 9,834E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,788E-04 0,01139124 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,869E-04 0,01149153 ! virus-host interaction GO:0019048 29 12 1,000 3,869E-04 0,01135139 ! cartilage condensation GO:0001502 20 12 1,000 3,869E-04 0,01121463 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 3,869E-04 0,01108112 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,869E-04 0,01095075 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 3,869E-04 0,01082342 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 3,869E-04 0,01069901 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,565E-04 0,01248071 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,565E-04 0,01234048 ! regulation of mRNA stability GO:0043488 31 13 1,000 4,565E-04 0,01220336 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 4,626E-04 0,01223118 ! regulation of mRNA processing GO:0050684 24 14 1,000 5,317E-04 0,01390559 ! regulation of RNA stability GO:0043487 32 14 1,000 5,317E-04 0,01375607 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 6,125E-04 0,01567856 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,989E-04 0,01770154 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 6,989E-04 0,01751715 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 6,989E-04 0,01733656 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 6,989E-04 0,01715966 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 6,989E-04 0,01698633 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 6,989E-04 0,01681647 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of homeostatic process GO:0032845 33 17 1,000 7,909E-04 0,01883996 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 7,909E-04 0,01865525 ! regulation of catabolic process GO:0009894 161 76 2,000 8,801E-04 0,02055827 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 8,883E-04 0,02055084 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 8,883E-04 0,02035512 ! lipid phosphorylation GO:0046834 35 19 1,000 9,912E-04 0,0224994 ! neuromuscular junction development GO:0007528 34 19 1,000 9,912E-04 0,02228912 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 9,912E-04 0,02208274 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 1,097E-03 0,02421589 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,1E-03 0,02405198 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,1E-03 0,0238353 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,1E-03 0,02362248 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,213E-03 0,02583689 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,213E-03 0,02561025 ! regulation of protein transport GO:0051223 154 87 2,000 1,302E-03 0,02723097 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 1,333E-03 0,02764158 ! regulation of chemotaxis GO:0050920 40 22 1,000 1,333E-03 0,02740533 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,333E-03 0,02717308 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,333E-03 0,02694473 ! ossification GO:0001503 188 90 2,000 1,435E-03 0,02877205 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,457E-03 0,02897702 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,457E-03 0,0287395 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 1,457E-03 0,02850585 ! sex determination GO:0007530 47 23 1,000 1,457E-03 0,02827596 ! bone development GO:0060348 189 91 2,000 1,481E-03 0,0285127 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,587E-03 0,03030867 ! regulation of behavior GO:0050795 43 24 1,000 1,587E-03 0,03007002 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,587E-03 0,0298351 ! protein tetramerization GO:0051262 52 24 1,000 1,587E-03 0,02960382 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 1,676E-03 0,03101823 ! myelination GO:0042552 45 25 1,000 1,723E-03 0,03163648 ! vasculogenesis GO:0001570 46 25 1,000 1,723E-03 0,03139681 ! interaction with host GO:0051701 62 25 1,000 1,723E-03 0,03116075 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 1,723E-03 0,0309282 ! regulation of protein localization GO:0032880 176 97 2,000 1,779E-03 0,03170552 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,863E-03 0,03296042 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,863E-03 0,03271983 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,863E-03 0,03248273 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 2,009E-03 0,03477369 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,009E-03 0,0345253 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,009E-03 0,03428044 ! dendrite development GO:0016358 59 28 1,000 2,16E-03 0,03659925 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,16E-03 0,03634331 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 2,316E-03 0,03870282 ! tissue homeostasis GO:0001894 48 29 1,000 2,316E-03 0,03843591 GO:0048871|multicellular organismal homeostasis, ! ensheathment of neurons GO:0007272 57 30 1,000 2,478E-03 0,04083439 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,478E-03 0,0405566 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,816E-03 0,04578582 ! peripheral nervous system development GO:0007422 64 32 1,000 2,816E-03 0,04547853 ! negative regulation of protein transport GO:0051224 69 33 1,000 2,993E-03 0,04801363 ! spermatid development GO:0007286 63 34 1,000 3,175E-03 0,05059631 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 3,175E-03 0,05026344 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 3,363E-03 0,05287734 ! calcium-mediated signaling GO:0019722 62 35 1,000 3,363E-03 0,05253398 ! regulation of microtubule-based process GO:0032886 78 35 1,000 3,363E-03 0,05219505 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 3,555E-03 0,05482407 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,555E-03 0,05447487 ! tissue remodeling GO:0048771 76 37 1,000 3,752E-03 0,05713258 ! spermatid differentiation GO:0048515 66 37 1,000 3,752E-03 0,05677326 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,954E-03 0,05945845 ! carbohydrate homeostasis GO:0033500 53 38 1,000 3,954E-03 0,05908914 GO:0042593|glucose homeostasis, ! mammary gland development GO:0030879 86 39 1,000 4,161E-03 0,06180065 ! regulation of action potential in neuron GO:0019228 73 39 1,000 4,161E-03 0,0614215 ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,59E-03 0,06734161 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,59E-03 0,06693347 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 4,812E-03 0,06974619 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 5,039E-03 0,07259536 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 5,748E-03 0,08232007 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 5,748E-03 0,08183297 ! positive regulation of protein transport GO:0051222 72 46 1,000 5,748E-03 0,0813516 ! positive regulation of DNA binding GO:0043388 73 47 1,000 5,994E-03 0,08433675 ! vascular process in circulatory system GO:0003018 80 47 1,000 5,994E-03 0,08384642 ! protein homooligomerization GO:0051260 76 47 1,000 5,994E-03 0,08336176 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,245E-03 0,08634951 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,245E-03 0,08585609 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 6,245E-03 0,08536827 ! regulation of action potential GO:0001508 95 49 1,000 6,5E-03 0,08835822 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 6,5E-03 0,08786182 ! negative regulation of immune system process GO:0002683 95 50 1,000 6,76E-03 0,09086758 ! positive regulation of binding GO:0051099 78 51 1,000 7,025E-03 0,0939024 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 7,025E-03 0,0933836 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 7,025E-03 0,0928705 ! regulation of angiogenesis GO:0045765 114 52 1,000 7,295E-03 0,09590575 ! positive regulation of growth GO:0045927 90 52 1,000 7,295E-03 0,09538453 ! cartilage development GO:0051216 90 52 1,000 7,295E-03 0,09486893 ! synapse organization GO:0050808 85 52 1,000 7,295E-03 0,09435889 ! response to UV GO:0009411 104 53 1,000 7,569E-03 0,09738077 ! activation of phospholipase C activity GO:0007202 103 54 1,000 7,847E-03 0,1004294 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 7,847E-03 0,09989802 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 8,131E-03 0,10295929 ! regulation of protein catabolic process GO:0042176 116 55 1,000 8,131E-03 0,10242023 ! heart morphogenesis GO:0003007 97 55 1,000 8,131E-03 0,10188679 ! skeletal muscle fiber development GO:0048741 111 56 1,000 8,418E-03 0,10494695 ! nucleotide-excision repair GO:0006289 83 56 1,000 8,418E-03 0,10440598 ! regulation of DNA replication GO:0006275 101 56 1,000 8,418E-03 0,10387057 ! regulation of bone remodeling GO:0046850 137 57 1,000 8,711E-03 0,10692939 ! muscle fiber development GO:0048747 112 57 1,000 8,711E-03 0,1063866 ! regulation of phospholipase activity GO:0010517 106 57 1,000 8,711E-03 0,10584929 ! regulation of tissue remodeling GO:0034103 140 58 1,000 9,008E-03 0,10890655 ! positive regulation of lipase activity GO:0060193 108 58 1,000 9,008E-03 0,10836202 ! skeletal system morphogenesis GO:0048705 105 59 1,000 9,309E-03 0,11143004 ! DNA catabolic process GO:0006308 86 59 1,000 9,309E-03 0,11087841 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 9,309E-03 0,11033221 ! viral reproductive process GO:0022415 126 62 1,000 0,0102397 0,12076825 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,0102397 0,12017913 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01055875 0,12332213 ! cell redox homeostasis GO:0045454 102 64 1,000 0,01088217 0,12648555 ! germ cell development GO:0007281 118 65 1,000 0,01120994 0,12966882 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01187842 0,13674394 ! lung development GO:0030324 144 67 1,000 0,01187842 0,13609278 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01187842 0,13544779 ! adaptive immune response GO:0002250 119 67 1,000 0,01187842 0,13480889 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01221909 0,13802412 ! viral reproduction GO:0016032 134 68 1,000 0,01221909 0,13737915 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01221909 0,13674018 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,012226 0,1361841 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,012226 0,13555652 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,012226 0,1349347 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,012226 0,13431856 ! neuron fate determination GO:0048664 7 5 0,000 0,012226 0,13370802 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,012226 0,13310301 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,012226 0,13250345 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,012226 0,13190926 ! polyol transport GO:0015791 12 5 0,000 0,012226 0,13132038 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,012226 0,13073673 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,012226 0,13015825 ! response to superoxide GO:0000303 10 5 0,000 0,012226 0,12958487 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,012226 0,12901651 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,012226 0,12845312 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,012226 0,12789463 ! female meiosis GO:0007143 7 5 0,000 0,012226 0,12734097 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,012226 0,12679209 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,012226 0,12624792 ! cobalt ion transport GO:0006824 11 5 0,000 0,012226 0,1257084 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,012226 0,12517347 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,012226 0,12464307 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,012226 0,12411715 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,012226 0,12359565 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,012226 0,12307851 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,012226 0,12256569 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,012226 0,12205712 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,012226 0,12155275 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,012226 0,12105253 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,012226 0,12055641 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,012226 0,12006435 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,012226 0,11957628 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,012226 0,11909217 ! negative chemotaxis GO:0050919 14 5 0,000 0,012226 0,11861195 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,012226 0,1181356 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,012226 0,11766306 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,012226 0,11719428 ! behavioral response to pain GO:0048266 9 5 0,000 0,012226 0,11672923 ! clathrin coat assembly GO:0048268 14 5 0,000 0,012226 0,11626785 ! Notch receptor processing GO:0007220 8 5 0,000 0,012226 0,1158101 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,012226 0,11535594 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,012226 0,11490533 ! micturition GO:0060073 9 5 0,000 0,012226 0,11445823 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,012226 0,11401459 ! copulation GO:0007620 9 5 0,000 0,012226 0,11357438 ! glial cell fate commitment GO:0021781 13 5 0,000 0,012226 0,11313756 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,012226 0,11270408 ! spermidine metabolic process GO:0008216 7 5 0,000 0,012226 0,11227391 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,012226 0,11184701 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,012226 0,11142335 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,012226 0,11100289 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,012226 0,11058558 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,012226 0,1101714 ! grooming behavior GO:0007625 6 5 0,000 0,012226 0,10976032 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,012226 0,10935229 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,012226 0,10894728 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,012226 0,10854526 ! response to protozoan GO:0001562 10 5 0,000 0,012226 0,10814619 ! lymph vessel development GO:0001945 10 5 0,000 0,012226 0,10775005 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,012226 0,10735681 ! endochondral ossification GO:0001958 16 5 0,000 0,012226 0,10696642 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,012226 0,10657886 ! parathyroid gland development GO:0060017 13 5 0,000 0,012226 0,1061941 ! anagen GO:0042640 6 5 0,000 0,012226 0,1058121 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,012226 0,10543285 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,012226 0,1050563 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,012226 0,10468244 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,012226 0,10431122 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,012226 0,10394263 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,012226 0,10357664 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,012226 0,10321321 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,012226 0,10285232 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,012226 0,10249395 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,012226 0,10213807 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,012226 0,10178465 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,012226 0,10143367 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,012226 0,1010851 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,012226 0,10073892 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,012226 0,1003951 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,012226 0,10005362 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,012226 0,09971446 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,012226 0,09937758 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,012226 0,09904298 ! histidine catabolic process GO:0006548 6 5 0,000 0,012226 0,09871062 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,012226 0,09838048 ! microvillus organization GO:0032528 7 5 0,000 0,012226 0,09805255 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,012226 0,09772679 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,012226 0,09740319 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,012226 0,09708173 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,012226 0,09676238 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,012226 0,09644513 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,012226 0,09612995 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,012226 0,09581682 ! polyol catabolic process GO:0046174 7 5 0,000 0,012226 0,09550573 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,012226 0,09519665 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,012226 0,09488956 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,012226 0,09458445 ! muscle cell migration GO:0014812 8 5 0,000 0,012226 0,0942813 ! mitochondrial fission GO:0000266 8 5 0,000 0,012226 0,09398008 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,012226 0,09368078 ! mRNA transcription GO:0009299 9 5 0,000 0,012226 0,09338338 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,012226 0,09308786 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,012226 0,09279421 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,012226 0,09250241 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,012226 0,09221243 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,012226 0,09192427 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,012226 0,0916379 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,012226 0,09135331 ! response to food GO:0032094 6 5 0,000 0,012226 0,09107048 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,012226 0,0907894 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,012226 0,09051005 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,012226 0,09023241 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,012226 0,08995647 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,012226 0,08968221 ! forebrain neuron development GO:0021884 13 5 0,000 0,012226 0,08940962 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,012226 0,08913868 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,012226 0,08886938 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,012226 0,0886017 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,012226 0,08833563 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,012226 0,08807115 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,012226 0,08780825 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,012226 0,08754692 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,012226 0,08728714 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,012226 0,08702889 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,012226 0,08677217 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,012226 0,08651696 ! basic amino acid transport GO:0015802 11 5 0,000 0,012226 0,08626324 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,012226 0,08601101 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,012226 0,08576025 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,012226 0,08551094 ! depyrimidination GO:0045008 10 5 0,000 0,012226 0,08526309 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,012226 0,08501666 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,012226 0,08477166 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,012226 0,08452806 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,012226 0,08428586 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,012226 0,08404504 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,012226 0,0838056 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,012226 0,08356751 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,012226 0,08333078 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,012226 0,08309538 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,012226 0,08286131 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,012226 0,08262855 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,012226 0,0823971 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,012226 0,08216694 ! response to arsenic GO:0046685 10 5 0,000 0,012226 0,08193806 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,012226 0,08171046 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,012226 0,08148411 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,012226 0,08125902 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,012226 0,08103516 ! response to cadmium ion GO:0046686 7 5 0,000 0,012226 0,08081254 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,012226 0,08059114 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,012226 0,08037094 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,012226 0,08015195 ! decidualization GO:0046697 11 5 0,000 0,012226 0,07993414 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,012226 0,07971752 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,012226 0,07950207 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,012226 0,07928778 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,012226 0,07907464 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,012226 0,07886264 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,012226 0,07865178 ! neural tube patterning GO:0021532 7 5 0,000 0,012226 0,07844204 ! embryonic cleavage GO:0040016 6 5 0,000 0,012226 0,07823342 ! peroxisome fission GO:0016559 5 5 0,000 0,012226 0,0780259 ! histone demethylation GO:0016577 10 5 0,000 0,012226 0,07781948 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,012226 0,07761416 ! mitotic recombination GO:0006312 9 5 0,000 0,012226 0,07740991 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,012226 0,07720673 ! metaphase plate congression GO:0051310 7 5 0,000 0,012226 0,07700462 ! regulation of sterol transport GO:0032371 7 5 0,000 0,012226 0,07680356 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,012226 0,07660355 ! enteric nervous system development GO:0048484 8 5 0,000 0,012226 0,07640458 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,012226 0,07620664 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,012226 0,07600973 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,012226 0,07581383 ! muscle cell proliferation GO:0033002 11 5 0,000 0,012226 0,07561893 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,012226 0,07542504 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,012226 0,07523214 ! plasminogen activation GO:0031639 5 5 0,000 0,012226 0,07504022 ! B cell homeostasis GO:0001782 13 5 0,000 0,012226 0,07484927 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,012226 0,0746593 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,012226 0,07447029 ! metaphase GO:0051323 8 5 0,000 0,012226 0,07428223 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,012226 0,07409513 ! cellular response to nutrient GO:0031670 8 5 0,000 0,012226 0,07390896 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,012226 0,07372372 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,012226 0,07353941 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,012226 0,07335602 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,012226 0,07317354 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,012226 0,07299197 ! response to redox state GO:0051775 5 5 0,000 0,012226 0,0728113 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,012226 0,07263152 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,012226 0,07245262 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,012226 0,07227461 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,012226 0,07209746 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,012226 0,07192119 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,012226 0,07174577 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,012226 0,0715712 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,012226 0,07139749 ! striatum development GO:0021756 9 5 0,000 0,012226 0,07122461 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,012226 0,07105257 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,012226 0,07088136 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,012226 0,07071097 ! glial cell migration GO:0008347 11 5 0,000 0,012226 0,0705414 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,012226 0,07037264 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,012226 0,07020469 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,012226 0,07003754 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,012226 0,06987118 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,012226 0,0697056 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,012226 0,06954082 ! neuroprotection GO:0043526 6 5 0,000 0,012226 0,0693768 ! neural plate development GO:0001840 8 5 0,000 0,012226 0,06921356 ! regulation of sensory perception GO:0051931 7 5 0,000 0,012226 0,06905109 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,012226 0,06888938 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,012226 0,06872842 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,012226 0,06856822 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,012226 0,06840876 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,012226 0,06825003 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,012226 0,06809205 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,012226 0,06793479 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,012226 0,06777826 ! spindle assembly GO:0051225 6 5 0,000 0,012226 0,06762245 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,012226 0,06746735 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,012226 0,06731296 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,012226 0,06715928 ! drug metabolic process GO:0017144 6 5 0,000 0,012226 0,0670063 ! stem cell division GO:0017145 11 5 0,000 0,012226 0,06685401 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,012226 0,06670241 ! organ regeneration GO:0031100 7 5 0,000 0,012226 0,0665515 ! carnitine metabolic process GO:0009437 7 5 0,000 0,012226 0,06640128 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,012226 0,06625172 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,012226 0,06610284 ! respiratory tube development GO:0030323 150 70 1,000 0,01291318 0,06966168 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01362411 0,07333248 ! respiratory system development GO:0060541 153 72 1,000 0,01362411 0,07316879 ! axon guidance GO:0007411 139 73 1,000 0,01398584 0,07494418 ! exocytosis GO:0006887 133 74 1,000 0,01435172 0,07673384 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01435172 0,0765637 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01465345 0,07800045 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01465345 0,07782826 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01465345 0,07765683 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01465345 0,07748616 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01465345 0,07731623 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01465345 0,07714705 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01465345 0,07697861 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01465345 0,0768109 ! sleep GO:0030431 13 6 0,000 0,01465345 0,07664392 ! response to oxygen radical GO:0000305 11 6 0,000 0,01465345 0,07647766 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01465345 0,07631212 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01465345 0,0761473 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01465345 0,07598319 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01465345 0,07581979 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01465345 0,07565709 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01465345 0,07549508 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01465345 0,07533376 ! forebrain regionalization GO:0021871 8 6 0,000 0,01465345 0,07517314 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01465345 0,07501319 ! male meiosis GO:0007140 7 6 0,000 0,01465345 0,07485393 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01465345 0,07469534 ! response to zinc ion GO:0010043 9 6 0,000 0,01465345 0,07453742 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01465345 0,07438017 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01465345 0,07422358 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01465345 0,07406765 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01465345 0,07391237 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01465345 0,07375774 ! malate metabolic process GO:0006108 11 6 0,000 0,01465345 0,07360376 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01465345 0,07345042 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01465345 0,07329772 ! protein refolding GO:0042026 15 6 0,000 0,01465345 0,07314565 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01465345 0,07299421 ! opsonization GO:0008228 8 6 0,000 0,01465345 0,07284339 ! mating behavior GO:0007617 7 6 0,000 0,01465345 0,0726932 ! neuron remodeling GO:0016322 15 6 0,000 0,01465345 0,07254362 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01465345 0,07239466 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01465345 0,07224631 ! equilibrioception GO:0050957 14 6 0,000 0,01465345 0,07209857 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01465345 0,07195143 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01465345 0,07180489 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01465345 0,07165895 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01465345 0,07151359 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01465345 0,07136883 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01465345 0,07122465 ! toxin metabolic process GO:0009404 11 6 0,000 0,01465345 0,07108105 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01465345 0,07093803 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01465345 0,07079559 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01465345 0,07065371 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01465345 0,0705124 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01465345 0,07037166 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01465345 0,07023148 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01465345 0,07009185 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01465345 0,06995278 ! thymic T cell selection GO:0045061 12 6 0,000 0,01465345 0,06981426 ! protein lipoylation GO:0009249 10 6 0,000 0,01465345 0,06967629 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01465345 0,06953886 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01465345 0,06940197 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01465345 0,06926562 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01465345 0,06912981 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01465345 0,06899452 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01465345 0,06885977 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01465345 0,06872554 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01465345 0,06859183 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01465345 0,06845864 ! hyperosmotic response GO:0006972 9 6 0,000 0,01465345 0,06832597 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01465345 0,06819381 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01465345 0,06806217 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01465345 0,06793102 ! urea metabolic process GO:0019627 7 6 0,000 0,01465345 0,06780039 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01465345 0,06767025 ! neutrophil activation GO:0042119 8 6 0,000 0,01465345 0,06754062 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01465345 0,06741148 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01465345 0,06728283 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01465345 0,06715467 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01465345 0,067027 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01465345 0,06689981 ! neuron apoptosis GO:0051402 9 6 0,000 0,01465345 0,06677311 ! nucleoside salvage GO:0043174 9 6 0,000 0,01465345 0,06664688 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01465345 0,06652114 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01465345 0,06639586 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01465345 0,06627106 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01465345 0,06614672 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01465345 0,06602285 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01465345 0,06589944 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01465345 0,0657765 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01465345 0,06565401 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01465345 0,06553197 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01465345 0,06541039 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01465345 0,06528926 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01465345 0,06516858 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01465345 0,06504834 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01465345 0,06492855 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01465345 0,06480919 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01465345 0,06469028 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01465345 0,0645718 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01465345 0,06445375 ! neural nucleus development GO:0048857 14 6 0,000 0,01465345 0,06433613 ! response to UV-C GO:0010225 11 6 0,000 0,01465345 0,06421895 ! astrocyte development GO:0014002 15 6 0,000 0,01465345 0,06410218 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01465345 0,06398585 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01465345 0,06386993 ! interaction with symbiont GO:0051702 13 6 0,000 0,01465345 0,06375443 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01465345 0,06363935 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01465345 0,06352469 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01465345 0,06341043 ! response to copper ion GO:0046688 10 6 0,000 0,01465345 0,06329659 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01465345 0,06318316 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01465345 0,06307013 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01465345 0,0629575 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01465345 0,06284528 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01465345 0,06273345 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01465345 0,06262203 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01465345 0,062511 ! hair follicle maturation GO:0048820 7 6 0,000 0,01465345 0,06240036 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01465345 0,06229011 ! Schwann cell development GO:0014044 15 6 0,000 0,01465345 0,06218025 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01465345 0,06207078 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01465345 0,06196169 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01465345 0,06185299 ! subpallium development GO:0021544 10 6 0,000 0,01465345 0,06174466 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01465345 0,06163672 ! histone ubiquitination GO:0016574 8 6 0,000 0,01465345 0,06152915 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01465345 0,06142195 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01465345 0,06131513 ! G2 phase GO:0051319 16 6 0,000 0,01465345 0,06120868 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01465345 0,0611026 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01465345 0,06099689 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01465345 0,06089154 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01465345 0,06078655 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01465345 0,06068193 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01465345 0,06057767 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01465345 0,06047376 ! receptor internalization GO:0031623 10 6 0,000 0,01465345 0,06037021 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01465345 0,06026701 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01465345 0,06016417 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01465345 0,06006167 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01465345 0,05995953 ! protein deubiquitination GO:0016579 14 6 0,000 0,01465345 0,05985773 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01465345 0,05975627 ! protein destabilization GO:0031648 9 6 0,000 0,01465345 0,05965516 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01465345 0,05955439 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01465345 0,05945397 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01465345 0,05935387 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01465345 0,05925412 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01465345 0,0591547 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01465345 0,05905561 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01465345 0,05895686 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01465345 0,05885843 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01465345 0,05876034 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01465345 0,05866257 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01465345 0,05856512 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01465345 0,058468 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01465345 0,05837119 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01465345 0,05827471 ! catecholamine transport GO:0051937 9 6 0,000 0,01465345 0,05817855 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01465345 0,0580827 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01465345 0,05798717 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01465345 0,05789196 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01465345 0,05779705 ! maternal placenta development GO:0001893 12 6 0,000 0,01465345 0,05770246 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01465345 0,05760817 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01465345 0,0575142 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01465345 0,05742052 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01465345 0,05732716 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01465345 0,05723409 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01465345 0,05714133 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01465345 0,05704887 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01472171 0,05722203 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01472171 0,05712974 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,01585622 0,06143328 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01624249 0,06282868 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01624249 0,06272783 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01702706 0,0656524 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01702706 0,06554736 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,01702706 0,06544265 ! tRNA transcription GO:0009304 14 7 0,000 0,01707501 0,0655223 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01707501 0,06541796 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01707501 0,06531396 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01707501 0,06521028 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01707501 0,06510694 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01707501 0,06500392 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01707501 0,06490123 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01707501 0,06479886 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01707501 0,06469682 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01707501 0,06459509 ! prostate gland development GO:0030850 13 7 0,000 0,01707501 0,06449369 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01707501 0,0643926 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01707501 0,06429183 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01707501 0,06419137 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01707501 0,06409123 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01707501 0,0639914 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01707501 0,06389188 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01707501 0,06379267 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01707501 0,06369377 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01707501 0,06359517 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01707501 0,06349688 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01707501 0,06339889 ! glycolipid transport GO:0046836 10 7 0,000 0,01707501 0,0633012 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01707501 0,06320381 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01707501 0,06310673 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01707501 0,06300994 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01707501 0,06291344 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01707501 0,06281725 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01707501 0,06272134 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01707501 0,06262573 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01707501 0,06253041 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01707501 0,06243538 ! pericardium development GO:0060039 14 7 0,000 0,01707501 0,06234064 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01707501 0,06224618 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01707501 0,06215201 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01707501 0,06205813 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01707501 0,06196452 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01707501 0,0618712 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01707501 0,06177816 ! lipoprotein transport GO:0042953 14 7 0,000 0,01707501 0,0616854 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01707501 0,06159292 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01707501 0,06150072 ! rhythmic behavior GO:0007622 15 7 0,000 0,01707501 0,06140879 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01707501 0,06131713 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01707501 0,06122575 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01707501 0,06113464 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01707501 0,0610438 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01707501 0,06095323 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01707501 0,06086293 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01707501 0,0607729 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01707501 0,06068313 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01707501 0,06059363 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01707501 0,06050439 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01707501 0,06041541 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01707501 0,06032669 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01707501 0,06023824 ! spinal cord patterning GO:0021511 13 7 0,000 0,01707501 0,06015004 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01707501 0,0600621 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01707501 0,05997442 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01707501 0,059887 ! adrenal gland development GO:0030325 17 7 0,000 0,01707501 0,05979982 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01707501 0,05971291 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01707501 0,05962624 ! ovulation GO:0030728 9 7 0,000 0,01707501 0,05953982 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01707501 0,05945366 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01707501 0,05936774 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01707501 0,05928208 ! microtubule nucleation GO:0007020 20 7 0,000 0,01707501 0,05919666 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01707501 0,05911148 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01707501 0,05902655 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01707501 0,05894186 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01707501 0,05885742 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01707501 0,05877322 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01707501 0,05868926 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01707501 0,05860553 ! galactose metabolic process GO:0006012 13 7 0,000 0,01707501 0,05852205 ! vesicle fusion GO:0006906 17 7 0,000 0,01707501 0,0584388 ! response to dietary excess GO:0002021 8 7 0,000 0,01707501 0,05835579 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01707501 0,05827302 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01707501 0,05819048 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01707501 0,05810817 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01707501 0,0580261 ! organ growth GO:0035265 15 7 0,000 0,01707501 0,05794426 ! purine salvage GO:0043101 10 7 0,000 0,01707501 0,05786265 ! nucleoside transport GO:0015858 8 7 0,000 0,01707501 0,05778126 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01707501 0,05770011 ! parturition GO:0007567 14 7 0,000 0,01707501 0,05761919 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01707501 0,05753849 ! rRNA modification GO:0000154 14 7 0,000 0,01707501 0,05745801 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01707501 0,05737776 ! spindle checkpoint GO:0031577 15 7 0,000 0,01707501 0,05729774 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01707501 0,05721794 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01707501 0,05713836 ! macrophage differentiation GO:0030225 11 7 0,000 0,01707501 0,057059 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01707501 0,05697986 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01707501 0,05690094 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01707501 0,05682224 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01707501 0,05674376 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01707501 0,05666549 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01707501 0,05658744 ! fibrinolysis GO:0042730 10 7 0,000 0,01707501 0,0565096 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01707501 0,05643198 ! eating behavior GO:0042755 7 7 0,000 0,01707501 0,05635457 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01707501 0,05627737 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01707501 0,05620038 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01707501 0,05612361 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01707501 0,05604704 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01707501 0,05597068 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01707501 0,05589453 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01707501 0,05581859 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01707501 0,05574285 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01707501 0,05566732 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01707501 0,05559199 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01707501 0,05551686 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01707501 0,05544194 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01707501 0,05536722 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01707501 0,0552927 ! regulation of meiosis GO:0040020 12 7 0,000 0,01707501 0,05521839 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01707501 0,05514427 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01707501 0,05507035 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01707501 0,05499663 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01707501 0,0549231 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01707501 0,05484977 ! transcription termination GO:0006353 13 7 0,000 0,01707501 0,05477664 ! response to tumor cell GO:0002347 13 7 0,000 0,01707501 0,0547037 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01707501 0,05463096 ! anaphase GO:0051322 17 7 0,000 0,01707501 0,05455841 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01707501 0,05448605 ! axonal fasciculation GO:0007413 18 7 0,000 0,01707501 0,05441388 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01707501 0,0543419 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01707501 0,05427012 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01707501 0,05419852 ! diuresis GO:0030146 12 7 0,000 0,01707501 0,05412711 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01707501 0,05405589 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01707501 0,05398486 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01707501 0,05391401 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01707501 0,05384335 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01707501 0,05377288 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01707501 0,05370259 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01707501 0,05363248 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01707501 0,05356255 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01707501 0,05349281 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01707501 0,05342325 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01707501 0,05335387 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01707501 0,05328467 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01707501 0,05321565 ! lymph node development GO:0048535 10 7 0,000 0,01707501 0,0531468 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01707501 0,05307814 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01707501 0,05300965 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01707501 0,05294134 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01707501 0,0528732 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01707501 0,05280524 ! adult feeding behavior GO:0008343 9 7 0,000 0,01707501 0,05273746 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01707501 0,05266985 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01707501 0,05260241 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01707501 0,05253514 ! muscle adaptation GO:0043500 14 7 0,000 0,01707501 0,05246804 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01707501 0,05240112 ! retina homeostasis GO:0001895 12 7 0,000 0,01707501 0,05233437 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01707501 0,05226779 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01707501 0,05220137 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01707501 0,05213513 ! protein prenylation GO:0018342 18 7 0,000 0,01707501 0,05206905 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01707501 0,05200314 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01707501 0,05193739 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01707501 0,05187182 ! response to oxygen levels GO:0070482 176 83 1,000 0,01782751 0,05408951 ! negative regulation of transport GO:0051051 153 84 1,000 0,01823364 0,05525205 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,01864367 0,05642349 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0194907 0,05891285 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0194907 0,05883893 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0194907 0,0587652 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0194907 0,05869165 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0194907 0,05861829 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0194907 0,05854511 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0194907 0,05847211 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0194907 0,05839929 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0194907 0,05832666 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0194907 0,0582542 ! meiotic prophase I GO:0007128 13 8 0,000 0,0194907 0,05818192 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0194907 0,05810983 ! oligopeptide transport GO:0006857 15 8 0,000 0,0194907 0,05803791 ! UTP metabolic process GO:0046051 8 8 0,000 0,0194907 0,05796617 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0194907 0,05789461 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0194907 0,05782322 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0194907 0,05775201 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0194907 0,05768097 ! succinate metabolic process GO:0006105 14 8 0,000 0,0194907 0,05761011 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0194907 0,05753942 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0194907 0,05746891 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0194907 0,05739857 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0194907 0,0573284 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0194907 0,0572584 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0194907 0,05718857 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0194907 0,05711892 ! reflex GO:0060004 16 8 0,000 0,0194907 0,05704943 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0194907 0,05698011 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0194907 0,05691096 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0194907 0,05684198 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0194907 0,05677316 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0194907 0,05670451 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0194907 0,05663603 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0194907 0,05656771 ! pigment granule organization GO:0048753 16 8 0,000 0,0194907 0,05649956 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0194907 0,05643157 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0194907 0,05636374 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0194907 0,05629608 ! histidine metabolic process GO:0006547 16 8 0,000 0,0194907 0,05622857 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0194907 0,05616123 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0194907 0,05609406 ! glycine catabolic process GO:0006546 13 8 0,000 0,0194907 0,05602704 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0194907 0,05596018 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0194907 0,05589348 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,0194907 0,05582694 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0194907 0,05576056 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0194907 0,05569434 ! melanin metabolic process GO:0006582 15 8 0,000 0,0194907 0,05562827 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0194907 0,05556236 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0194907 0,0554966 ! macrophage activation GO:0042116 12 8 0,000 0,0194907 0,05543101 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0194907 0,05536556 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0194907 0,05530027 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0194907 0,05523514 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0194907 0,05517015 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0194907 0,05510532 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0194907 0,05504065 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0194907 0,05497612 ! osteoblast development GO:0002076 16 8 0,000 0,0194907 0,05491175 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0194907 0,05484752 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0194907 0,05478345 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0194907 0,05471952 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0194907 0,05465575 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0194907 0,05459212 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0194907 0,05452864 ! response to UV-B GO:0010224 16 8 0,000 0,0194907 0,05446531 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0194907 0,05440212 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0194907 0,05433909 ! intermediate filament organization GO:0045109 12 8 0,000 0,0194907 0,05427619 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0194907 0,05421345 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0194907 0,05415084 ! cellular extravasation GO:0045123 12 8 0,000 0,0194907 0,05408839 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0194907 0,05402607 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0194907 0,0539639 ! response to antibiotic GO:0046677 11 8 0,000 0,0194907 0,05390187 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0194907 0,05383999 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0194907 0,05377825 ! DNA topological change GO:0006265 12 8 0,000 0,0194907 0,05371665 ! response to tropane GO:0014073 15 8 0,000 0,0194907 0,05365518 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0194907 0,05359386 ! melanosome transport GO:0032402 13 8 0,000 0,0194907 0,05353268 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0194907 0,05347164 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0194907 0,05341074 ! mast cell activation GO:0045576 14 8 0,000 0,0194907 0,05334998 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0194907 0,05328935 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0194907 0,05322887 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0194907 0,05316852 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0194907 0,0531083 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0194907 0,05304823 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0194907 0,05298828 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0194907 0,05292848 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0194907 0,05286881 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0194907 0,05280927 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0194907 0,05274987 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0194907 0,0526906 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0194907 0,05263146 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0194907 0,05257246 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0194907 0,05251358 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0194907 0,05245484 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0194907 0,05239624 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0194907 0,05233776 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0194907 0,05227941 ! hormone catabolic process GO:0042447 17 8 0,000 0,0194907 0,05222119 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0194907 0,0521631 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0194907 0,05210515 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0194907 0,05204732 ! ATP catabolic process GO:0006200 11 8 0,000 0,0194907 0,05198961 ! blastocyst growth GO:0001832 19 8 0,000 0,0194907 0,05193204 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0194907 0,05187459 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0194907 0,05181727 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0194907 0,05176008 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0194907 0,05170301 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0194907 0,05164607 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0194907 0,05158925 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0194907 0,05153256 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0194907 0,05147599 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0194907 0,05141955 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0194907 0,05136323 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0194907 0,05130704 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0194907 0,05125096 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0194907 0,05119501 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0194907 0,05113918 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0194907 0,05108348 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0194907 0,05102789 ! regulation of DNA binding GO:0051101 155 88 1,000 0,01989702 0,05203503 ! gland development GO:0048732 206 88 1,000 0,01989702 0,05197853 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02032248 0,0530324 ! axon extension GO:0048675 15 9 0,000 0,02190054 0,05708851 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02190054 0,05702672 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02190054 0,05696507 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02190054 0,05690355 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02190054 0,05684217 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02190054 0,05678092 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02190054 0,0567198 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02190054 0,05665881 ! phosphate transport GO:0006817 19 9 0,000 0,02190054 0,05659795 ! reproductive behavior GO:0019098 19 9 0,000 0,02190054 0,05653722 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02190054 0,05647663 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02190054 0,05641616 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02190054 0,05635582 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02190054 0,05629561 ! GTP metabolic process GO:0046039 9 9 0,000 0,02190054 0,05623553 ! RNA methylation GO:0001510 15 9 0,000 0,02190054 0,05617558 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02190054 0,05611575 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02190054 0,05605605 ! artery development GO:0060840 24 9 0,000 0,02190054 0,05599648 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02190054 0,05593704 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02190054 0,05587772 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02190054 0,05581853 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02190054 0,05575946 ! chemosensory behavior GO:0007635 20 9 0,000 0,02190054 0,05570052 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02190054 0,0556417 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02190054 0,05558301 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02190054 0,05552444 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02190054 0,05546599 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02190054 0,05540767 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02190054 0,05534947 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02190054 0,05529139 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02190054 0,05523343 ! protein targeting to ER GO:0045047 22 9 0,000 0,02190054 0,05517559 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02190054 0,05511788 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02190054 0,05506028 ! T cell selection GO:0045058 23 9 0,000 0,02190054 0,05500281 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02190054 0,05494546 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02190054 0,05488822 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02190054 0,0548311 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02190054 0,05477411 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02190054 0,05471723 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02190054 0,05466047 ! mannose metabolic process GO:0006013 13 9 0,000 0,02190054 0,05460383 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02190054 0,0545473 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02190054 0,05449089 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02190054 0,0544346 ! receptor clustering GO:0043113 18 9 0,000 0,02190054 0,05437842 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02190054 0,05432236 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02190054 0,05426642 ! ruffle organization GO:0031529 15 9 0,000 0,02190054 0,05421059 ! retinol metabolic process GO:0042572 18 9 0,000 0,02190054 0,05415487 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02190054 0,05409927 ! behavioral fear response GO:0001662 22 9 0,000 0,02190054 0,05404379 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02190054 0,05398841 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02190054 0,05393315 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02190054 0,05387801 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02190054 0,05382297 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02190054 0,05376805 ! segment specification GO:0007379 13 9 0,000 0,02190054 0,05371324 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02190054 0,05365855 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02190054 0,05360396 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02190054 0,05354948 ! response to amine stimulus GO:0014075 13 9 0,000 0,02190054 0,05349512 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02190054 0,05344086 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02190054 0,05338672 ! erythrocyte development GO:0048821 15 9 0,000 0,02190054 0,05333268 ! gas homeostasis GO:0033483 16 9 0,000 0,02190054 0,05327876 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02190054 0,05322494 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02190054 0,05317123 ! renal water homeostasis GO:0003091 14 9 0,000 0,02190054 0,05311763 ! postreplication repair GO:0006301 22 9 0,000 0,02190054 0,05306414 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02190054 0,05301076 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02190054 0,05295748 ! icosanoid secretion GO:0032309 15 9 0,000 0,02190054 0,05290431 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02190054 0,05285125 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02190054 0,05279829 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02190054 0,05274544 ! regulation of cell division GO:0051302 15 9 0,000 0,02190054 0,05269269 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02190054 0,05264005 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02190054 0,05258752 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02190054 0,05253509 ! sterol catabolic process GO:0016127 11 9 0,000 0,02190054 0,05248276 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02190054 0,05243054 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02190054 0,05237842 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02190054 0,05232641 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02190054 0,0522745 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02190054 0,05222269 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02190054 0,05217098 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02190054 0,05211938 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02190054 0,05206788 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02190054 0,05201648 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02190054 0,05196518 ! purine base metabolic process GO:0006144 21 9 0,000 0,02190054 0,05191398 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02190054 0,05186289 ! pigment granule transport GO:0051904 17 9 0,000 0,02190054 0,05181189 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02190054 0,05176099 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02190054 0,0517102 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02190054 0,0516595 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02190054 0,0516089 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02190054 0,05155841 ! mitochondrion localization GO:0051646 15 9 0,000 0,02190054 0,05150801 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02206213 0,05183738 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,02206213 0,05178681 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02250639 0,05277815 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,02295436 0,05377623 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,02386131 0,05584661 ! protein ubiquitination GO:0016567 217 97 1,000 0,02386131 0,05579234 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02430453 0,05677349 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02430453 0,05671842 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02430453 0,05666346 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02430453 0,05660861 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02430453 0,05655386 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02430453 0,05649922 ! synapsis GO:0007129 13 10 0,000 0,02430453 0,05644469 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02430453 0,05639025 ! N-glycan processing GO:0006491 20 10 0,000 0,02430453 0,05633593 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02430453 0,05628171 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02430453 0,05622759 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02430453 0,05617358 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02430453 0,05611967 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02430453 0,05606586 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02430453 0,05601216 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02430453 0,05595856 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02430453 0,05590506 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02430453 0,05585167 ! androgen metabolic process GO:0008209 17 10 0,000 0,02430453 0,05579837 ! phospholipid efflux GO:0033700 16 10 0,000 0,02430453 0,05574518 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02430453 0,05569209 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02430453 0,0556391 ! pathogenesis GO:0009405 13 10 0,000 0,02430453 0,05558621 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02430453 0,05553342 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02430453 0,05548073 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02430453 0,05542815 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02430453 0,05537566 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02430453 0,05532327 ! endoderm development GO:0007492 16 10 0,000 0,02430453 0,05527098 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02430453 0,05521879 ! arginine catabolic process GO:0006527 13 10 0,000 0,02430453 0,05516669 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02430453 0,0551147 ! proline metabolic process GO:0006560 13 10 0,000 0,02430453 0,0550628 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02430453 0,055011 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02430453 0,0549593 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02430453 0,05490769 ! V(D)J recombination GO:0033151 28 10 0,000 0,02430453 0,05485619 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02430453 0,05480477 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02430453 0,05475346 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02430453 0,05470224 ! B cell proliferation GO:0042100 18 10 0,000 0,02430453 0,05465112 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02430453 0,05460009 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02430453 0,05454915 ! multicellular organism growth GO:0035264 18 10 0,000 0,02430453 0,05449832 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02430453 0,05444757 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02430453 0,05439692 ! epithelial cell development GO:0002064 20 10 0,000 0,02430453 0,05434637 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02430453 0,05429591 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02430453 0,05424554 ! macroautophagy GO:0016236 17 10 0,000 0,02430453 0,05419527 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02430453 0,05414509 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02430453 0,054095 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02430453 0,054045 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02430453 0,0539951 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02430453 0,05394529 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02430453 0,05389557 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02430453 0,05384594 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02430453 0,05379641 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02430453 0,05374696 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02430453 0,05369761 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02430453 0,05364834 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02430453 0,05359917 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02430453 0,05355009 ! response to dsRNA GO:0043331 20 10 0,000 0,02430453 0,05350109 ! DNA ligation GO:0006266 19 10 0,000 0,02430453 0,05345219 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02430453 0,05340337 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02430453 0,05335465 ! melanosome localization GO:0032400 16 10 0,000 0,02430453 0,05330601 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02430453 0,05325746 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02430453 0,053209 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02430453 0,05316063 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02430453 0,05311235 ! mRNA cleavage GO:0006379 17 10 0,000 0,02430453 0,05306415 ! protein sumoylation GO:0016925 15 10 0,000 0,02430453 0,05301604 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02430453 0,05296802 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02430453 0,05292008 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02430453 0,05287224 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02430453 0,05282447 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02430453 0,0527768 ! salivary gland development GO:0007431 27 10 0,000 0,02430453 0,05272921 ! prophase GO:0051324 15 10 0,000 0,02430453 0,05268171 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02430453 0,05263429 ! apical protein localization GO:0045176 15 10 0,000 0,02430453 0,05258695 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02430453 0,05253971 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02430453 0,05249254 ! midbrain development GO:0030901 13 10 0,000 0,02430453 0,05244547 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02430453 0,05239847 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02430453 0,05235156 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02430453 0,05230473 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02430453 0,05225799 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02430453 0,05221133 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02430453 0,05216476 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02430453 0,05211827 ! detection of calcium ion GO:0005513 23 10 0,000 0,02430453 0,05207186 ! oocyte development GO:0048599 17 10 0,000 0,02430453 0,05202553 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02430453 0,05197928 ! blastocyst formation GO:0001825 17 10 0,000 0,02430453 0,05193312 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02430453 0,05188704 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02430453 0,05184104 ! activation of innate immune response GO:0002218 12 10 0,000 0,02430453 0,05179512 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02430453 0,05174929 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02430453 0,05170353 ! response to nicotine GO:0035094 20 10 0,000 0,02430453 0,05165786 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02430453 0,05161226 ! interphase GO:0051325 213 98 1,000 0,02432026 0,05160012 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02478282 0,05253522 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,02524899 0,05347628 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02670269 0,05650543 ! respiratory burst GO:0045730 17 11 0,000 0,02670269 0,05645577 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02670269 0,05640621 ! neuron fate specification GO:0048665 17 11 0,000 0,02670269 0,05635673 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02670269 0,05630734 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02670269 0,05625803 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02670269 0,05620881 ! thyroid gland development GO:0030878 26 11 0,000 0,02670269 0,05615968 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02670269 0,05611063 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02670269 0,05606167 ! response to pain GO:0048265 24 11 0,000 0,02670269 0,05601279 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02670269 0,055964 ! T cell proliferation GO:0042098 26 11 0,000 0,02670269 0,05591529 ! bone resorption GO:0045453 16 11 0,000 0,02670269 0,05586667 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02670269 0,05581813 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02670269 0,05576968 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02670269 0,05572131 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02670269 0,05567303 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02670269 0,05562482 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02670269 0,05557671 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02670269 0,05552867 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02670269 0,05548072 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02670269 0,05543285 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02670269 0,05538506 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02670269 0,05533736 ! lipid digestion GO:0044241 18 11 0,000 0,02670269 0,05528973 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02670269 0,05524219 ! UV protection GO:0009650 19 11 0,000 0,02670269 0,05519474 ! adult heart development GO:0007512 14 11 0,000 0,02670269 0,05514736 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02670269 0,05510006 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02670269 0,05505285 ! temperature homeostasis GO:0001659 17 11 0,000 0,02670269 0,05500571 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02670269 0,05495866 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02670269 0,05491169 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02670269 0,05486479 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02670269 0,05481798 ! regulation of organ growth GO:0046620 13 11 0,000 0,02670269 0,05477125 ! pigment granule localization GO:0051875 20 11 0,000 0,02670269 0,05472459 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02670269 0,05467802 ! vasoconstriction GO:0042310 18 11 0,000 0,02670269 0,05463152 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02670269 0,05458511 ! embryonic axis specification GO:0000578 18 11 0,000 0,02670269 0,05453877 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02670269 0,05449251 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02670269 0,05444633 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02670269 0,05440023 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02670269 0,05435421 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02670269 0,05430826 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02670269 0,05426239 ! zymogen activation GO:0031638 15 11 0,000 0,02670269 0,0542166 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02670269 0,05417089 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02670269 0,05412525 ! nucleosome positioning GO:0016584 15 11 0,000 0,02670269 0,05407969 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02670269 0,05403421 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02670269 0,0539888 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02670269 0,05394347 ! acid secretion GO:0046717 18 11 0,000 0,02670269 0,05389821 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02670269 0,05385304 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02670269 0,05380793 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02670269 0,05376291 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02670269 0,05371795 ! oocyte differentiation GO:0009994 18 11 0,000 0,02670269 0,05367308 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02670269 0,05362827 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02670269 0,05358355 ! cholesterol efflux GO:0033344 19 11 0,000 0,02670269 0,05353889 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02670269 0,05349431 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02670269 0,05344981 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02670269 0,05340538 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02670269 0,05336102 ! embryonic gut development GO:0048566 15 11 0,000 0,02670269 0,05331674 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02670269 0,05327253 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02670269 0,05322839 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02670269 0,05318433 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02670269 0,05314034 ! defense response to fungus GO:0050832 13 11 0,000 0,02670269 0,05309642 ! developmental induction GO:0031128 19 11 0,000 0,02670269 0,05305258 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02670269 0,0530088 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02670269 0,0529651 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02670269 0,05292148 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02670269 0,05287792 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02670269 0,05283443 ! nucleus localization GO:0051647 19 11 0,000 0,02670269 0,05279102 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02670269 0,05274768 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02909504 0,0574263 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02909504 0,05737923 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02909504 0,05733223 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02909504 0,05728532 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02909504 0,05723848 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02909504 0,05719171 ! mating GO:0007618 17 12 0,000 0,02909504 0,05714503 ! protein complex disassembly GO:0043241 27 12 0,000 0,02909504 0,05709842 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02909504 0,05705188 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02909504 0,05700542 ! hippocampus development GO:0021766 26 12 0,000 0,02909504 0,05695904 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02909504 0,05691273 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02909504 0,0568665 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02909504 0,05682034 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02909504 0,05677426 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02909504 0,05672825 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02909504 0,05668231 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02909504 0,05663646 ! drug transport GO:0015893 16 12 0,000 0,02909504 0,05659067 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02909504 0,05654496 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02909504 0,05649932 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02909504 0,05645376 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02909504 0,05640827 ! focal adhesion formation GO:0048041 35 12 0,000 0,02909504 0,05636285 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02909504 0,0563175 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02909504 0,05627223 ! forebrain cell migration GO:0021885 21 12 0,000 0,02909504 0,05622704 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02909504 0,05618191 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02909504 0,05613686 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02909504 0,05609187 ! entry into host cell GO:0030260 32 12 0,000 0,02909504 0,05604696 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02909504 0,05600213 ! monoamine transport GO:0015844 18 12 0,000 0,02909504 0,05595736 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02909504 0,05591267 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02909504 0,05586804 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02909504 0,05582349 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02909504 0,05577901 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02909504 0,0557346 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02909504 0,05569026 ! protein homotetramerization GO:0051289 21 12 0,000 0,02909504 0,05564599 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02909504 0,05560179 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02909504 0,05555767 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02909504 0,05551361 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02909504 0,05546962 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02909504 0,0554257 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02909504 0,05538185 ! cranial nerve development GO:0021545 20 12 0,000 0,02909504 0,05533807 ! fucose catabolic process GO:0019317 22 12 0,000 0,02909504 0,05529436 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02909504 0,05525072 ! histone acetylation GO:0016573 26 12 0,000 0,02909504 0,05520714 ! histone methylation GO:0016571 26 12 0,000 0,02909504 0,05516364 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02909504 0,0551202 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02909504 0,05507684 ! gland morphogenesis GO:0022612 29 12 0,000 0,02909504 0,05503354 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02909504 0,05499031 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02909504 0,05494714 ! T cell homeostasis GO:0043029 25 12 0,000 0,02909504 0,05490405 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02909504 0,05486102 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02909504 0,05481806 ! spleen development GO:0048536 22 12 0,000 0,02909504 0,05477516 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02909504 0,05473234 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02909504 0,05468958 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02909504 0,05464688 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02909504 0,05460426 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02909504 0,0545617 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02909504 0,0545192 ! response to cold GO:0009409 17 12 0,000 0,02909504 0,05447678 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02909504 0,05443442 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02909504 0,05439212 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03148158 0,05880799 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03148158 0,05876236 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03148158 0,05871681 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03148158 0,05867133 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03148158 0,05862592 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03148158 0,05858058 ! lipid localization GO:0010876 28 13 0,000 0,03148158 0,05853531 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03148158 0,05849011 ! organelle fusion GO:0048284 32 13 0,000 0,03148158 0,05844498 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03148158 0,05839991 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03148158 0,05835492 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03148158 0,05831 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03148158 0,05826514 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03148158 0,05822036 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03148158 0,05817564 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03148158 0,058131 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03148158 0,05808642 ! methionine metabolic process GO:0006555 27 13 0,000 0,03148158 0,05804191 ! plasma membrane organization GO:0007009 24 13 0,000 0,03148158 0,05799746 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03148158 0,05795309 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03148158 0,05790878 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03148158 0,05786454 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03148158 0,05782037 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03148158 0,05777627 ! response to X-ray GO:0010165 25 13 0,000 0,03148158 0,05773223 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03148158 0,05768826 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03148158 0,05764436 ! exocrine system development GO:0035272 32 13 0,000 0,03148158 0,05760052 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03148158 0,05755675 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03148158 0,05751305 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03148158 0,05746941 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03148158 0,05742584 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03148158 0,05738234 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03148158 0,0573389 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03148158 0,05729553 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03148158 0,05725222 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03148158 0,05720898 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03148158 0,0571658 ! ribosome assembly GO:0042255 17 13 0,000 0,03148158 0,05712269 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03148158 0,05707964 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03148158 0,05703666 ! chromatin silencing GO:0006342 26 13 0,000 0,03148158 0,05699375 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03148158 0,05695089 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03148158 0,05690811 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03148158 0,05686538 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03148158 0,05682272 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03148158 0,05678013 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03148158 0,05673759 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03148158 0,05669513 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03148158 0,05665272 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03148158 0,05661038 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03148158 0,0565681 ! embryonic placenta development GO:0001892 23 13 0,000 0,03148158 0,05652589 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03148158 0,05648373 ! insulin secretion GO:0030073 23 13 0,000 0,03148158 0,05644165 ! actin filament polymerization GO:0030041 24 13 0,000 0,03148158 0,05639962 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03148158 0,05635766 ! acrosome reaction GO:0007340 18 13 0,000 0,03148158 0,05631575 ! rRNA transcription GO:0009303 25 14 0,000 0,03386234 0,06052956 ! lactation GO:0007595 26 14 0,000 0,03386234 0,06048463 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03386234 0,06043976 ! reproductive cellular process GO:0048610 20 14 0,000 0,03386234 0,06039495 ! tRNA modification GO:0006400 20 14 0,000 0,03386234 0,06035022 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03386234 0,06030555 ! regulation of S phase GO:0033261 23 14 0,000 0,03386234 0,06026094 ! water transport GO:0006833 21 14 0,000 0,03386234 0,0602164 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03386234 0,06017193 ! non-recombinational repair GO:0000726 25 14 0,000 0,03386234 0,06012752 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03386234 0,06008318 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03386234 0,0600389 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03386234 0,05999469 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03386234 0,05995055 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03386234 0,05990647 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03386234 0,05986245 ! palate development GO:0060021 31 14 0,000 0,03386234 0,0598185 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03386234 0,05977461 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03386234 0,05973079 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03386234 0,05968703 ! arginine metabolic process GO:0006525 17 14 0,000 0,03386234 0,05964333 ! regulation of heart rate GO:0002027 24 14 0,000 0,03386234 0,0595997 ! organic alcohol transport GO:0015850 29 14 0,000 0,03386234 0,05955614 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03386234 0,05951263 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03386234 0,05946919 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03386234 0,05942582 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03386234 0,0593825 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03386234 0,05933925 ! L-amino acid transport GO:0015807 30 14 0,000 0,03386234 0,05929607 ! bone mineralization GO:0030282 17 14 0,000 0,03386234 0,05925294 ! stem cell development GO:0048864 43 14 0,000 0,03386234 0,05920988 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03386234 0,05916688 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03386234 0,05912394 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03386234 0,05908107 ! cerebellum development GO:0021549 21 14 0,000 0,03386234 0,05903826 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03386234 0,05899551 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03386234 0,05895282 ! response to gamma radiation GO:0010332 28 14 0,000 0,03386234 0,05891019 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03386234 0,05886763 ! cofactor transport GO:0051181 26 14 0,000 0,03386234 0,05882512 ! NADP metabolic process GO:0006739 24 14 0,000 0,03386234 0,05878268 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03386234 0,0587403 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03386234 0,05869798 ! intestinal absorption GO:0050892 25 14 0,000 0,03386234 0,05865572 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03386234 0,05861352 ! oxygen transport GO:0015671 21 14 0,000 0,03386234 0,05857138 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03386234 0,05852931 ! male genitalia development GO:0030539 24 14 0,000 0,03386234 0,05848729 ! regulation of axon extension GO:0030516 37 14 0,000 0,03386234 0,05844533 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03386234 0,05840344 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03386234 0,0583616 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03623733 0,06241017 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03623733 0,06236553 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03623733 0,06232095 ! superoxide anion generation GO:0042554 20 15 0,000 0,03623733 0,06227643 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03623733 0,06223198 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03623733 0,0621876 ! copper ion transport GO:0006825 20 15 0,000 0,03623733 0,06214327 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03623733 0,06209901 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03623733 0,06205481 ! sulfate transport GO:0008272 23 15 0,000 0,03623733 0,06201067 ! response to cAMP GO:0051591 22 15 0,000 0,03623733 0,0619666 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03623733 0,06192259 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03623733 0,06187864 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03623733 0,06183476 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03623733 0,06179093 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03623733 0,06174717 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03623733 0,06170347 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03623733 0,06165984 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03623733 0,06161626 ! pituitary gland development GO:0021983 29 15 0,000 0,03623733 0,06157275 ! vesicle coating GO:0006901 33 15 0,000 0,03623733 0,06152929 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03623733 0,0614859 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03623733 0,06144257 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03623733 0,0613993 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03623733 0,06135609 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03623733 0,06131295 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03623733 0,06126986 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03623733 0,06122683 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03623733 0,06118387 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03623733 0,06114096 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03623733 0,06109811 ! histone deacetylation GO:0016575 20 15 0,000 0,03623733 0,06105533 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03623733 0,0610126 ! tissue regeneration GO:0042246 26 15 0,000 0,03623733 0,06096994 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03623733 0,06092733 ! water homeostasis GO:0030104 27 15 0,000 0,03623733 0,06088478 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03623733 0,0608423 ! muscle maintenance GO:0046716 26 15 0,000 0,03623733 0,06079987 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03623733 0,0607575 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03623733 0,06071519 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03623733 0,06067294 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03623733 0,06063074 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03623733 0,06058861 ! cell killing GO:0001906 29 15 0,000 0,03623733 0,06054653 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03623733 0,06050452 ! detection of bacterium GO:0016045 18 15 0,000 0,03623733 0,06046256 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03623733 0,06042066 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03623733 0,06037882 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03623733 0,06033703 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03623733 0,0602953 ! peptide hormone processing GO:0016486 23 15 0,000 0,03623733 0,06025363 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03860655 0,06414873 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03860655 0,06410446 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03860655 0,06406025 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03860655 0,0640161 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03860655 0,06397202 ! bone remodeling GO:0046849 27 16 0,000 0,03860655 0,06392799 ! filopodium assembly GO:0046847 32 16 0,000 0,03860655 0,06388402 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03860655 0,06384011 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03860655 0,06379627 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03860655 0,06375248 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03860655 0,06370876 ! startle response GO:0001964 28 16 0,000 0,03860655 0,06366509 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03860655 0,06362148 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03860655 0,06357794 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03860655 0,06353445 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03860655 0,06349102 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03860655 0,06344765 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03860655 0,06340435 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03860655 0,0633611 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03860655 0,0633179 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03860655 0,06327477 ! response to osmotic stress GO:0006970 25 16 0,000 0,03860655 0,0632317 ! lysosomal transport GO:0007041 26 16 0,000 0,03860655 0,06318868 ! fructose metabolic process GO:0006000 25 16 0,000 0,03860655 0,06314573 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03860655 0,06310283 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03860655 0,06305999 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03860655 0,06301721 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03860655 0,06297449 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03860655 0,06293182 ! axon cargo transport GO:0008088 43 16 0,000 0,03860655 0,06288921 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03860655 0,06284666 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03860655 0,06280417 ! DNA replication initiation GO:0006270 27 16 0,000 0,03860655 0,06276173 ! neuron recognition GO:0008038 35 16 0,000 0,03860655 0,06271936 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03860655 0,06267704 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03860655 0,06263477 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03860655 0,06259256 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03860655 0,06255042 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03860655 0,06250832 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03860655 0,06246629 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03860655 0,06242431 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03860655 0,06238238 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03860655 0,06234051 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03860655 0,0622987 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03860655 0,06225695 ! defense response to virus GO:0051607 37 16 0,000 0,03860655 0,06221525 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04097003 0,06597985 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04097003 0,06593572 ! metencephalon development GO:0022037 30 17 0,000 0,04097003 0,06589164 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04097003 0,06584763 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04097003 0,06580367 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04097003 0,06575977 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04097003 0,06571593 ! signal complex assembly GO:0007172 41 17 0,000 0,04097003 0,06567215 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04097003 0,06562843 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04097003 0,06558476 ! glial cell development GO:0021782 27 17 0,000 0,04097003 0,06554116 ! limbic system development GO:0021761 36 17 0,000 0,04097003 0,06549761 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04097003 0,06545412 ! adult walking behavior GO:0007628 33 17 0,000 0,04097003 0,06541068 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04097003 0,06536731 ! heart looping GO:0001947 30 17 0,000 0,04097003 0,06532399 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04097003 0,06528073 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04097003 0,06523752 ! myoblast differentiation GO:0045445 45 17 0,000 0,04097003 0,06519438 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04097003 0,06515129 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04097003 0,06510826 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04097003 0,06506528 ! glycine metabolic process GO:0006544 28 17 0,000 0,04097003 0,06502236 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04097003 0,0649795 ! NAD metabolic process GO:0019674 29 17 0,000 0,04097003 0,06493669 ! membrane budding GO:0006900 37 17 0,000 0,04097003 0,06489394 ! DNA integration GO:0015074 29 17 0,000 0,04097003 0,06485125 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04097003 0,06480861 ! regulation of protein binding GO:0043393 33 17 0,000 0,04097003 0,06476603 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04097003 0,06472351 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04097003 0,06468104 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04097003 0,06463862 ! genitalia development GO:0048806 30 17 0,000 0,04097003 0,06459626 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04097003 0,06455396 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04097003 0,06451171 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04097003 0,06446952 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04097003 0,06442739 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04097003 0,0643853 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04097003 0,06434328 ! steroid catabolic process GO:0006706 31 17 0,000 0,04097003 0,0643013 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04097003 0,06425939 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04097003 0,06421752 ! gas transport GO:0015669 25 17 0,000 0,04097003 0,06417572 ! organic cation transport GO:0015695 31 17 0,000 0,04097003 0,06413396 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04097003 0,06409226 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04097003 0,06405062 ! microspike assembly GO:0030035 36 17 0,000 0,04097003 0,06400903 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04097003 0,06396749 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04332778 0,06760483 ! neuron maturation GO:0042551 42 18 0,000 0,04332778 0,06756101 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04332778 0,06751725 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04332778 0,06747355 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04332778 0,06742991 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04332778 0,06738632 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04332778 0,06734279 ! memory GO:0007613 31 18 0,000 0,04332778 0,06729932 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04332778 0,0672559 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04332778 0,06721253 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04332778 0,06716923 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04332778 0,06712598 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04332778 0,06708278 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04332778 0,06703964 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04332778 0,06699656 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04332778 0,06695353 ! response to retinoic acid GO:0032526 26 18 0,000 0,04332778 0,06691055 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04332778 0,06686763 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04332778 0,06682477 ! response to fungus GO:0009620 21 18 0,000 0,04332778 0,06678196 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04332778 0,06673921 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04332778 0,06669651 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04332778 0,06665386 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04332778 0,06661127 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04332778 0,06656874 ! vitamin transport GO:0051180 27 18 0,000 0,04332778 0,06652625 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04332778 0,06648383 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04332778 0,06644145 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04332778 0,06639913 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04332778 0,06635687 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04332778 0,06631466 ! nerve development GO:0021675 28 18 0,000 0,04332778 0,0662725 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04332778 0,06623039 ! protein secretion GO:0009306 39 19 0,000 0,04567981 0,06978135 ! positive regulation of translation GO:0045727 30 19 0,000 0,04567981 0,06973707 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04567981 0,06969285 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04567981 0,06964869 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04567981 0,06960458 ! skin development GO:0043588 36 19 0,000 0,04567981 0,06956052 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04567981 0,06951652 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04567981 0,06947258 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04567981 0,0694287 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04567981 0,06938486 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04567981 0,06934109 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04567981 0,06929737 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04567981 0,0692537 ! cerebral cortex development GO:0021987 36 19 0,000 0,04567981 0,06921009 ! pigmentation during development GO:0048066 41 19 0,000 0,04567981 0,06916654 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04567981 0,06912303 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04567981 0,06907959 ! heme metabolic process GO:0042168 36 19 0,000 0,04567981 0,0690362 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04567981 0,06899286 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04567981 0,06894958 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04567981 0,06890635 ! peptide cross-linking GO:0018149 37 19 0,000 0,04567981 0,06886317 ! protein export from nucleus GO:0006611 36 19 0,000 0,04567981 0,06882005 ! heart process GO:0003015 30 19 0,000 0,04567981 0,06877699 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04567981 0,06873397 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04567981 0,06869102 ! visual learning GO:0008542 36 19 0,000 0,04567981 0,06864811 ! cellular pigmentation GO:0033059 36 19 0,000 0,04567981 0,06860526 ! G1 phase GO:0051318 40 19 0,000 0,04567981 0,06856246 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04567981 0,06851972 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04567981 0,06847703 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04567981 0,06843439 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04567981 0,0683918 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04567981 0,06834927 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04567981 0,06830679 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04567981 0,06826436 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04567981 0,06822199 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04567981 0,06817967 ! cilium assembly GO:0042384 37 19 0,000 0,04567981 0,0681374 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04567981 0,06809518 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04802614 0,07154853 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04802614 0,07150426 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04802614 0,07146004 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04802614 0,07141587 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04802614 0,07137176 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04802614 0,07132771 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04802614 0,0712837 ! response to vitamin GO:0033273 31 20 0,000 0,04802614 0,07123976 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04802614 0,07119586 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04802614 0,07115202 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04802614 0,07110824 ! response to alkaloid GO:0043279 38 20 0,000 0,04802614 0,0710645 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04802614 0,07102083 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04802614 0,0709772 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04802614 0,07093363 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04802614 0,07089011 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04802614 0,07084665 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04802614 0,07080324 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04802614 0,07075988 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04802614 0,07071657 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04802614 0,07067332 ! body fluid secretion GO:0007589 31 20 0,000 0,04802614 0,07063012 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04802614 0,07058698 ! peptide secretion GO:0002790 35 20 0,000 0,04802614 0,07054388 ! stem cell differentiation GO:0048863 53 20 0,000 0,04802614 0,07050084 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04802614 0,07045786 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04802614 0,07041492 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04802614 0,07037204 ! sensory perception of pain GO:0019233 30 20 0,000 0,04802614 0,0703292 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04802614 0,07028643 ! diencephalon development GO:0021536 34 20 0,000 0,04802614 0,0702437 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04802614 0,07020102 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04802614 0,0701584 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04802614 0,07011583 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04802614 0,07007331 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04802614 0,07003084 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04802614 0,06998842 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04802614 0,06994606 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04802614 0,06990374 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04802614 0,06986148 ! regulation of glucose import GO:0046324 29 20 0,000 0,04802614 0,06981926 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04802614 0,0697771 ! actin filament-based movement GO:0030048 43 20 0,000 0,04802614 0,06973499 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04802614 0,06969293 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04802614 0,06965092 ! negative regulation of translation GO:0017148 29 20 0,000 0,04802614 0,06960897 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04802614 0,06956706 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04802614 0,0695252 ! regulation of cell killing GO:0031341 42 21 0,000 0,05036677 0,07286978 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05036677 0,07282599 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05036677 0,07278225 ! hormone secretion GO:0046879 38 21 0,000 0,05036677 0,07273856 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05036677 0,07269493 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05036677 0,07265135 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05036677 0,07260782 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05036677 0,07256434 ! axis specification GO:0009798 38 21 0,000 0,05036677 0,07252092 ! ovarian follicle development GO:0001541 35 21 0,000 0,05036677 0,07247754 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05036677 0,07243422 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05036677 0,07239095 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05036677 0,07234773 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05036677 0,07230456 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05036677 0,07226145 ! cell aging GO:0007569 44 21 0,000 0,05036677 0,07221838 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05036677 0,07217537 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05036677 0,07213241 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05036677 0,0720895 ! cytolysis GO:0019835 24 21 0,000 0,05036677 0,07204664 ! vasodilation GO:0042311 39 21 0,000 0,05036677 0,07200383 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05036677 0,07196107 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05036677 0,07191837 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05036677 0,07187571 ! oogenesis GO:0048477 36 21 0,000 0,05036677 0,07183311 ! DNA modification GO:0006304 34 21 0,000 0,05036677 0,07179055 ! collagen fibril organization GO:0030199 59 21 0,000 0,05036677 0,07174805 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05036677 0,07170559 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05036677 0,07166319 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05036677 0,07162083 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05036677 0,07157853 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05036677 0,07153627 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05036677 0,07149407 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05036677 0,07145192 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05036677 0,07140981 ! collagen catabolic process GO:0030574 28 21 0,000 0,05036677 0,07136776 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05036677 0,07132575 ! gut development GO:0048565 39 21 0,000 0,05036677 0,07128379 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05270173 0,07454459 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05270173 0,0745008 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05270173 0,07445705 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05270173 0,07441335 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05270173 0,07436971 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05270173 0,07432612 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05270173 0,07428257 ! regeneration GO:0031099 41 22 0,000 0,05270173 0,07423908 ! keratinization GO:0031424 28 22 0,000 0,05270173 0,07419564 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05270173 0,07415225 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05270173 0,07410892 ! sensory perception of taste GO:0050909 28 22 0,000 0,05270173 0,07406563 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05270173 0,07402239 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05270173 0,0739792 ! vacuolar transport GO:0007034 36 22 0,000 0,05270173 0,07393607 ! lysosome organization GO:0007040 41 22 0,000 0,05270173 0,07389298 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05270173 0,07384994 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05270173 0,07380696 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05270173 0,07376402 ! fucose metabolic process GO:0006004 39 22 0,000 0,05270173 0,07372114 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05270173 0,0736783 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05270173 0,07363551 ! ureteric bud development GO:0001657 43 22 0,000 0,05270173 0,07359278 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05270173 0,07355009 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05270173 0,07350745 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05270173 0,07346486 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05270173 0,07342232 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05270173 0,07337984 ! sarcomere organization GO:0045214 30 22 0,000 0,05270173 0,07333739 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,05270173 0,073295 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05270173 0,07325266 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05270173 0,07321037 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05270173 0,07316812 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05270173 0,07312593 ! protein stabilization GO:0050821 39 22 0,000 0,05270173 0,07308378 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05503102 0,07626995 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05503102 0,07622604 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05503102 0,07618218 ! gluconeogenesis GO:0006094 33 23 0,000 0,05503102 0,07613837 ! viral genome replication GO:0019079 41 23 0,000 0,05503102 0,07609462 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05503102 0,07605091 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05503102 0,07600725 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05503102 0,07596365 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05503102 0,07592009 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05503102 0,07587658 ! visual behavior GO:0007632 42 23 0,000 0,05503102 0,07583312 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05503102 0,07578972 ! response to ethanol GO:0045471 46 23 0,000 0,05503102 0,07574636 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05503102 0,07570305 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05503102 0,07565979 ! peroxisome organization GO:0007031 37 23 0,000 0,05503102 0,07561658 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05503102 0,07557342 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05503102 0,07553031 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05503102 0,07548725 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05503102 0,07544424 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,05503102 0,07540127 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05503102 0,07535836 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05503102 0,07531549 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05503102 0,07527267 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05503102 0,07522991 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05503102 0,07518719 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05503102 0,07514451 ! fatty acid transport GO:0015908 44 23 0,000 0,05503102 0,07510189 ! platelet activation GO:0030168 37 23 0,000 0,05503102 0,07505932 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05503102 0,07501679 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05503102 0,07497431 ! hormone transport GO:0009914 40 23 0,000 0,05503102 0,07493188 ! cell-cell recognition GO:0009988 25 23 0,000 0,05503102 0,0748895 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05503102 0,07484716 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05503102 0,07480488 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05503102 0,07476264 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05503102 0,07472045 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05503102 0,0746783 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05735466 0,07778767 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05735466 0,07774384 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05735466 0,07770007 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05735466 0,07765634 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05735466 0,07761267 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05735466 0,07756904 ! vesicle docking GO:0048278 47 24 0,000 0,05735466 0,07752546 ! spinal cord development GO:0021510 47 24 0,000 0,05735466 0,07748193 ! vacuole organization GO:0007033 43 24 0,000 0,05735466 0,07743845 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05735466 0,07739502 ! digestive system process GO:0022600 39 24 0,000 0,05735466 0,07735164 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05735466 0,0773083 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05735466 0,07726502 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05735466 0,07722178 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05735466 0,07717859 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05735466 0,07713545 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05735466 0,07709236 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05735466 0,07704931 ! membrane depolarization GO:0051899 39 24 0,000 0,05735466 0,07700632 ! pallium development GO:0021543 49 24 0,000 0,05735466 0,07696337 ! pentose metabolic process GO:0019321 35 24 0,000 0,05735466 0,07692047 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05735466 0,07687761 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05735466 0,07683481 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05735466 0,07679205 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05735466 0,07674934 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05735466 0,07670668 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05735466 0,07666407 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05735466 0,0766215 ! regulation of amine transport GO:0051952 40 24 0,000 0,05735466 0,07657898 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05967267 0,07962975 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05967267 0,07958561 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05967267 0,07954152 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05967267 0,07949748 ! phototransduction GO:0007602 33 25 0,000 0,05967267 0,07945348 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05967267 0,07940954 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,05967267 0,07936564 ! sperm motility GO:0030317 31 25 0,000 0,05967267 0,07932179 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05967267 0,07927799 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05967267 0,07923424 ! receptor metabolic process GO:0043112 46 25 0,000 0,05967267 0,07919054 ! chromosome condensation GO:0030261 45 25 0,000 0,05967267 0,07914688 ! response to starvation GO:0042594 42 25 0,000 0,05967267 0,07910327 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05967267 0,07905971 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,05967267 0,0790162 ! neural crest cell development GO:0014032 54 25 0,000 0,05967267 0,07897274 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05967267 0,07892932 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05967267 0,07888596 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05967267 0,07884264 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05967267 0,07879936 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05967267 0,07875614 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05967267 0,07871296 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,05967267 0,07866983 ! immunoglobulin production GO:0002377 55 25 0,000 0,05967267 0,07862675 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05967267 0,07858371 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05967267 0,07854072 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05967267 0,07849778 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05967267 0,07845489 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05967267 0,07841204 ! telomere organization GO:0032200 43 25 0,000 0,05967267 0,07836924 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05967267 0,07832648 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05967267 0,07828377 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06198505 0,08127304 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06198505 0,08122878 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06198505 0,08118456 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06198505 0,08114039 ! initiation of viral infection GO:0019059 57 26 0,000 0,06198505 0,08109627 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06198505 0,08105219 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06198505 0,08100817 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06198505 0,08096419 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06198505 0,08092026 ! molting cycle process GO:0022404 50 26 0,000 0,06198505 0,08087637 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06198505 0,08083254 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06198505 0,08078875 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06198505 0,08074501 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06198505 0,08070132 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,06198505 0,08065767 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06198505 0,08061407 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06198505 0,08057052 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06198505 0,08052702 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06198505 0,08048356 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06198505 0,08044015 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06198505 0,08039678 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06198505 0,08035347 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06198505 0,0803102 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06198505 0,08026697 ! blastocyst development GO:0001824 49 26 0,000 0,06198505 0,08022379 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06198505 0,08018066 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06198505 0,08013758 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06198505 0,08009454 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,06429182 0,08303067 ! neuron fate commitment GO:0048663 48 27 0,000 0,06429182 0,08298612 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06429182 0,08294162 ! iron ion transport GO:0006826 59 27 0,000 0,06429182 0,08289718 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06429182 0,08285277 ! protein amino acid acylation GO:0043543 55 27 0,000 0,06429182 0,08280842 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06429182 0,08276411 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06429182 0,08271986 ! fat cell differentiation GO:0045444 50 27 0,000 0,06429182 0,08267564 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06429182 0,08263148 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,06429182 0,08258736 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06429182 0,08254329 ! autophagy GO:0006914 41 27 0,000 0,06429182 0,08249927 ! male gonad development GO:0008584 44 27 0,000 0,06429182 0,08245529 ! response to toxin GO:0009636 47 27 0,000 0,06429182 0,08241136 ! primary neural tube formation GO:0014020 51 27 0,000 0,06429182 0,08236748 ! base-excision repair GO:0006284 41 27 0,000 0,06429182 0,08232365 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06429182 0,08227986 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06429182 0,08223611 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06429182 0,08219242 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06429182 0,08214877 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06429182 0,08210516 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06429182 0,08206161 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06429182 0,0820181 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,066593 0,08490872 ! circadian rhythm GO:0007623 50 28 0,000 0,066593 0,08486375 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,066593 0,08481883 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,066593 0,08477395 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,066593 0,08472912 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,066593 0,08468433 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,066593 0,0846396 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,066593 0,08459491 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,066593 0,08455027 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,066593 0,08450568 ! synaptogenesis GO:0007416 42 28 0,000 0,066593 0,08446113 ! lipid oxidation GO:0034440 43 28 0,000 0,066593 0,08441663 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,066593 0,08437218 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,066593 0,08432777 ! translational initiation GO:0006413 65 29 0,000 0,06888859 0,08718883 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06888859 0,08714299 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06888859 0,08709719 ! regulation of pH GO:0006885 43 29 0,000 0,06888859 0,08705145 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06888859 0,08700575 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06888859 0,0869601 ! catechol metabolic process GO:0009712 54 29 0,000 0,06888859 0,0869145 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06888859 0,08686895 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06888859 0,08682345 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06888859 0,08677799 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06888859 0,08673258 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06888859 0,08668722 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06888859 0,0866419 ! cell fate determination GO:0001709 60 29 0,000 0,06888859 0,08659663 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06888859 0,08655141 ! detection of light stimulus GO:0009583 38 29 0,000 0,06888859 0,08650624 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,06888859 0,08646112 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06888859 0,08641604 ! regulation of coagulation GO:0050818 46 29 0,000 0,06888859 0,08637101 ! phenol metabolic process GO:0018958 55 30 0,000 0,07117862 0,08919571 ! zinc ion transport GO:0006829 45 30 0,000 0,07117862 0,08914927 ! membrane docking GO:0022406 61 30 0,000 0,07117862 0,08910289 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07117862 0,08905656 ! cell junction assembly GO:0034329 78 30 0,000 0,07117862 0,08901027 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07117862 0,08896403 ! acute-phase response GO:0006953 49 30 0,000 0,07117862 0,08891784 ! myofibril assembly GO:0030239 47 30 0,000 0,07117862 0,0888717 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07117862 0,0888256 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07117862 0,08877955 ! phospholipid transport GO:0015914 51 30 0,000 0,07117862 0,08873355 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07117862 0,0886876 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07117862 0,0886417 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07117862 0,08859584 ! eye morphogenesis GO:0048592 60 30 0,000 0,07117862 0,08855003 ! regulation of B cell activation GO:0050864 50 30 0,000 0,07117862 0,08850427 ! response to heat GO:0009408 50 30 0,000 0,07117862 0,08845855 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07346309 0,09125048 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07346309 0,0912034 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07346309 0,09115636 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07346309 0,09110937 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,07346309 0,09106244 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07346309 0,09101554 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07346309 0,0909687 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07346309 0,09092191 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,07346309 0,09087516 ! ovulation cycle process GO:0022602 49 31 0,000 0,07346309 0,09082846 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07346309 0,09078181 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07346309 0,09073521 ! peptide transport GO:0015833 55 31 0,000 0,07346309 0,09068865 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,07346309 0,09064215 ! iron ion homeostasis GO:0055072 54 31 0,000 0,07346309 0,09059569 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07346309 0,09054928 ! mesoderm formation GO:0001707 69 31 0,000 0,07346309 0,09050291 ! natural killer cell activation GO:0030101 45 31 0,000 0,07346309 0,09045659 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,07346309 0,09041033 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07346309 0,0903641 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07346309 0,09031793 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,07346309 0,0902718 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07346309 0,09022572 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07574201 0,09297718 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07574201 0,09292977 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07574201 0,09288241 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07574201 0,09283509 ! cholesterol transport GO:0030301 56 32 0,000 0,07574201 0,09278782 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07574201 0,0927406 ! spliceosome assembly GO:0000245 67 32 0,000 0,07574201 0,09269343 ! spindle organization GO:0007051 46 32 0,000 0,07574201 0,0926463 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07574201 0,09259923 ! metanephros development GO:0001656 74 32 0,000 0,07574201 0,0925522 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07574201 0,09250522 ! response to ionizing radiation GO:0010212 65 32 0,000 0,07574201 0,09245828 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07574201 0,0924114 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07574201 0,09236456 ! muscle cell development GO:0055001 49 32 0,000 0,07574201 0,09231777 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07574201 0,09227103 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07574201 0,09222433 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07574201 0,09217768 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07574201 0,09213108 ! ovulation cycle GO:0042698 51 32 0,000 0,07574201 0,09208453 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07574201 0,09203802 ! hindbrain development GO:0030902 61 32 0,000 0,07574201 0,09199156 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07574201 0,09194515 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07574201 0,09189878 ! gene silencing GO:0016458 65 32 0,000 0,07574201 0,09185246 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,07801541 0,09456175 ! post-embryonic development GO:0009791 69 33 0,000 0,07801541 0,09451413 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,07801541 0,09446657 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07801541 0,09441905 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,07801541 0,09437158 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07801541 0,09432415 ! formation of primary germ layer GO:0001704 72 33 0,000 0,07801541 0,09427678 ! cell fate specification GO:0001708 52 33 0,000 0,07801541 0,09422945 ! sterol transport GO:0015918 57 33 0,000 0,07801541 0,09418217 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,07801541 0,09413494 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07801541 0,09408775 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07801541 0,09404062 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07801541 0,09399352 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08028329 0,09667747 ! glial cell differentiation GO:0010001 63 34 0,000 0,08028329 0,09662911 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08028329 0,09658079 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08028329 0,09653253 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08028329 0,09648431 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08028329 0,09643614 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08028329 0,09638802 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08028329 0,09633994 ! mismatch repair GO:0006298 46 34 0,000 0,08028329 0,09629192 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08028329 0,09624394 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08028329 0,09619601 ! placenta development GO:0001890 53 34 0,000 0,08028329 0,09614813 ! regulation of muscle development GO:0048634 70 35 0,000 0,08254566 0,09880839 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08254566 0,09875925 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,08254566 0,09871017 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08254566 0,09866113 ! odontogenesis GO:0042476 66 35 0,000 0,08254566 0,09861214 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08254566 0,09856321 ! female gonad development GO:0008585 58 35 0,000 0,08254566 0,09851432 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08254566 0,09846547 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,08254566 0,09841668 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,08254566 0,09836793 ! cytokine production GO:0001816 59 35 0,000 0,08254566 0,09831924 ! neural tube formation GO:0001841 67 35 0,000 0,08254566 0,09827059 ! vesicle localization GO:0051648 64 35 0,000 0,08254566 0,09822199 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08480255 0,1008576 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,08480255 0,10080777 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08480255 0,10075799 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08480255 0,10070826 ! cell junction organization GO:0034330 86 36 0,000 0,08480255 0,10065857 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08480255 0,10060894 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,08480255 0,10055935 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08480255 0,10050982 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,08480255 0,10046033 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08480255 0,10041089 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08480255 0,1003615 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,08480255 0,10031216 ! aerobic respiration GO:0009060 55 36 0,000 0,08480255 0,10026286 ! embryonic organ development GO:0048568 57 36 0,000 0,08480255 0,10021362 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08480255 0,10016442 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08705395 0,10277322 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08705395 0,10272281 ! meiosis I GO:0007127 65 37 0,000 0,08705395 0,10267246 ! sister chromatid segregation GO:0000819 58 37 0,000 0,08705395 0,10262215 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08705395 0,1025719 ! organic anion transport GO:0015711 68 37 0,000 0,08705395 0,10252169 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,08705395 0,10247153 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08705395 0,10242142 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08705395 0,10237137 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,08705395 0,10232135 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08705395 0,10227139 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,08705395 0,10222148 ! pigment metabolic process GO:0042440 80 37 0,000 0,08705395 0,10217162 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,0892999 0,10475649 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,0892999 0,10470544 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,0892999 0,10465444 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,0892999 0,10460348 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,0892999 0,10455258 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,0892999 0,10450173 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,0892999 0,10445093 ! lipid homeostasis GO:0055088 67 38 0,000 0,0892999 0,10440017 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,0892999 0,10434947 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,0892999 0,10429881 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,0892999 0,10424821 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,0892999 0,10419765 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,0892999 0,10414714 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,0892999 0,10409668 ! glucan metabolic process GO:0044042 62 38 0,000 0,0892999 0,10404627 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09154039 0,10660512 ! learning GO:0007612 77 39 0,000 0,09154039 0,10655355 ! ear morphogenesis GO:0042471 60 39 0,000 0,09154039 0,10650202 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09154039 0,10645055 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09154039 0,10639912 ! segmentation GO:0035282 67 39 0,000 0,09154039 0,10634775 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09154039 0,10629642 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09154039 0,10624514 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09154039 0,10619392 ! RNA modification GO:0009451 57 39 0,000 0,09154039 0,10614274 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09154039 0,10609161 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09377545 0,10862962 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09377545 0,10857735 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09377545 0,10852512 ! feeding behavior GO:0007631 59 40 0,000 0,09377545 0,10847295 ! negative regulation of binding GO:0051100 72 40 0,000 0,09377545 0,10842082 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09377545 0,10836875 ! mesenchymal cell development GO:0014031 87 40 0,000 0,09377545 0,10831672 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09377545 0,10826474 ! maintenance of protein location GO:0045185 91 40 0,000 0,09377545 0,10821282 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09600508 0,11073261 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,09600508 0,11067955 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09600508 0,11062654 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09600508 0,11057359 ! gliogenesis GO:0042063 88 41 0,000 0,09600508 0,11052068 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,09600508 0,11046782 ! T cell differentiation GO:0030217 81 41 0,000 0,09600508 0,11041502 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,09600508 0,11036226 ! female gamete generation GO:0007292 61 41 0,000 0,09600508 0,11030956 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,09600508 0,11025691 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,0982293 0,11275749 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0982293 0,11270372 ! regulation of tube size GO:0035150 71 42 0,000 0,0982293 0,11265 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0982293 0,11259633 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0982293 0,11254271 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,0982293 0,11248914 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,0982293 0,11243563 ! neuron migration GO:0001764 79 42 0,000 0,0982293 0,11238216 ! regulation of protein secretion GO:0050708 71 42 0,000 0,0982293 0,11232875 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0982293 0,11227539 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10044812 0,11475697 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10044812 0,1147025 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10044812 0,11464809 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,10044812 0,11459373 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10044812 0,11453942 ! glucose transport GO:0015758 65 43 0,000 0,10044812 0,11448516 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10044812 0,11443095 ! neural tube development GO:0021915 77 43 0,000 0,10044812 0,1143768 ! phagocytosis GO:0006909 90 43 0,000 0,10044812 0,11432269 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10044812 0,11426864 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10266155 0,11673143 ! hexose transport GO:0008645 67 44 0,000 0,10266155 0,11667629 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10266155 0,1166212 ! male sex differentiation GO:0046661 76 44 0,000 0,10266155 0,11656616 ! double-strand break repair GO:0006302 81 44 0,000 0,10266155 0,11651118 ! biopolymer methylation GO:0043414 84 44 0,000 0,10266155 0,11645625 ! B cell differentiation GO:0030183 107 44 0,000 0,10266155 0,11640137 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10266155 0,11634654 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10266155 0,11629176 ! developmental growth GO:0048589 82 44 0,000 0,10266155 0,11623703 ! maintenance of location in cell GO:0051651 97 44 0,000 0,10266155 0,11618236 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,10486962 0,11862543 ! glycolysis GO:0006096 65 45 0,000 0,10486962 0,11856969 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,10486962 0,118514 ! leukocyte migration GO:0050900 68 45 0,000 0,10486962 0,11845835 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,10486962 0,11840277 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,10486962 0,11834723 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,10486962 0,11829175 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,10486962 0,11823631 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,10486962 0,11818093 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,10486962 0,11812561 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,10486962 0,11807033 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,10486962 0,11801511 ! cell growth GO:0016049 84 45 0,000 0,10486962 0,11795993 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,10707232 0,12038131 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,10707232 0,12032508 ! pigmentation GO:0043473 100 46 0,000 0,10707232 0,12026891 ! positive regulation of defense response GO:0031349 76 47 0,000 0,10926967 0,12267981 ! response to calcium ion GO:0051592 81 47 0,000 0,10926967 0,12262259 ! endosome transport GO:0016197 108 47 0,000 0,10926967 0,12256542 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,10926967 0,12250831 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,10926967 0,12245125 ! JNK cascade GO:0007254 91 47 0,000 0,10926967 0,12239424 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,10926967 0,12233729 ! methylation GO:0032259 90 47 0,000 0,10926967 0,12228039 ! mitochondrial transport GO:0006839 82 48 0,000 0,11146169 0,12467542 ! Notch signaling pathway GO:0007219 96 48 0,000 0,11146169 0,12461749 ! cellular component disassembly GO:0022411 86 48 0,000 0,11146169 0,12455961 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11146169 0,12450178 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11146169 0,12444401 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11146169 0,12438629 ! activation of caspase activity GO:0006919 84 48 0,000 0,11146169 0,12432862 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11146169 0,12427101 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,11146169 0,12421345 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11364839 0,12659168 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,11364839 0,1265331 ! regulation of ion transport GO:0043269 77 49 0,000 0,11364839 0,12647457 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,11364839 0,1264161 ! peptide metabolic process GO:0006518 76 49 0,000 0,11364839 0,12635768 ! response to temperature stimulus GO:0009266 76 49 0,000 0,11364839 0,12629932 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11364839 0,12624101 ! endocrine system development GO:0035270 104 49 0,000 0,11364839 0,12618275 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11364839 0,12612455 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,11364839 0,1260664 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11364839 0,12600831 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,11364839 0,12595027 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,11582978 0,12830868 ! neuromuscular process GO:0050905 99 50 0,000 0,11582978 0,12824963 ! regulation of ossification GO:0030278 117 50 0,000 0,11582978 0,12819064 ! inner ear development GO:0048839 79 50 0,000 0,11582978 0,1281317 ! histone modification GO:0016570 91 50 0,000 0,11582978 0,12807282 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,11582978 0,12801399 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,11582978 0,12795521 ! viral infectious cycle GO:0019058 99 51 0,000 0,11800587 0,13029928 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,11800587 0,13023951 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,11800587 0,13017979 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,11800587 0,13012013 ! excretion GO:0007588 83 51 0,000 0,11800587 0,13006053 ! chromatin remodeling GO:0006338 109 51 0,000 0,11800587 0,13000098 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,11800587 0,12994148 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,11800587 0,12988204 ! vesicle organization GO:0016050 107 51 0,000 0,11800587 0,12982265 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,11800587 0,12976331 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,12017668 0,13209004 ! membrane fusion GO:0006944 110 52 0,000 0,12017668 0,13202973 ! covalent chromatin modification GO:0016569 101 52 0,000 0,12017668 0,13196947 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,12017668 0,13190926 ! amino acid activation GO:0043038 92 52 0,000 0,12017668 0,13184911 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,12234222 0,1341638 ! RNA catabolic process GO:0006401 93 53 0,000 0,12234222 0,13410268 ! regulation of translational initiation GO:0006446 82 53 0,000 0,12234222 0,13404161 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,12234222 0,1339806 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,12234222 0,13391965 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,12234222 0,13385875 ! cell maturation GO:0048469 100 53 0,000 0,12234222 0,1337979 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,12234222 0,13373711 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,12234222 0,13367638 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,1245025 0,13597504 ! cell recognition GO:0008037 85 54 0,000 0,1245025 0,13591335 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,1245025 0,13585171 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,1245025 0,13579013 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,1245025 0,1357286 ! chloride transport GO:0006821 90 55 0,000 0,12665754 0,13801541 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,12665754 0,13795294 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,12665754 0,13789051 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,12665754 0,13782815 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,12665754 0,13776584 ! aging GO:0007568 103 55 0,000 0,12665754 0,13770359 ! gastrulation GO:0007369 112 55 0,000 0,12665754 0,13764139 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,12665754 0,13757925 ! nuclear export GO:0051168 97 55 0,000 0,12665754 0,13751716 ! regulation of actin filament length GO:0030832 105 56 0,000 0,12880734 0,13978821 ! sensory perception of smell GO:0007608 80 56 0,000 0,12880734 0,13972518 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,12880734 0,13966222 ! proton transport GO:0015992 94 56 0,000 0,12880734 0,13959931 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,12880734 0,13953645 ! maintenance of location GO:0051235 118 57 0,000 0,13095192 0,14179582 ! hydrogen transport GO:0006818 97 58 0,000 0,13309129 0,14404753 ! regulation of endocytosis GO:0030100 91 58 0,000 0,13309129 0,14398276 ! adult behavior GO:0030534 99 58 0,000 0,13309129 0,14391805 ! positive regulation of secretion GO:0051047 95 59 0,000 0,13522547 0,14616015 ! regulation of cellular component size GO:0032535 109 59 0,000 0,13522547 0,14609451 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,13522547 0,14602894 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,13522547 0,14596343 ! establishment of organelle localization GO:0051656 109 59 0,000 0,13522547 0,14589797 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,13735447 0,14812857 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,13735447 0,14806221 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,13735447 0,1479959 ! regulation of heart contraction GO:0008016 110 60 0,000 0,13735447 0,14792965 ! camera-type eye development GO:0043010 116 60 0,000 0,13735447 0,14786347 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,13735447 0,14779734 ! kidney development GO:0001822 122 60 0,000 0,13735447 0,14773127 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,13947829 0,14994851 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,13947829 0,14988154 ! mesoderm development GO:0007498 119 61 0,000 0,13947829 0,14981463 ! tRNA processing GO:0008033 89 61 0,000 0,13947829 0,14974778 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,13947829 0,14968098 ! ear development GO:0043583 103 62 0,000 0,14159695 0,15188688 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,14159695 0,1518192 ! gonad development GO:0008406 98 62 0,000 0,14159695 0,15175157 ! regulation of mitosis GO:0007088 105 63 0,000 0,14371047 0,15394809 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,14371047 0,15387957 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,14371047 0,15381112 ! detection of external stimulus GO:0009581 91 63 0,000 0,14371047 0,15374273 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,14371047 0,1536744 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,14581886 0,1558597 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,14581886 0,15579049 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,14581886 0,15572134 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,14581886 0,15565225 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,14792212 0,15782733 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,14792212 0,15775737 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,14792212 0,15768748 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,14792212 0,15761764 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,15002028 0,15978256 ! actin filament organization GO:0007015 148 66 0,000 0,15002028 0,15971186 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,15002028 0,15964122 ! extracellular matrix organization GO:0030198 133 66 0,000 0,15002028 0,15957064 ! secondary metabolic process GO:0019748 116 66 0,000 0,15002028 0,15950013 ! developmental maturation GO:0021700 116 66 0,000 0,15002028 0,15942968 ! cell projection assembly GO:0030031 120 66 0,000 0,15002028 0,15935929 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15211334 0,16151134 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,15211334 0,16144009 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,15211334 0,16136891 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,15211334 0,16129779 ! chromosome segregation GO:0007059 113 67 0,000 0,15211334 0,16122674 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15211334 0,16115574 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,15211334 0,16108481 ! hexose catabolic process GO:0019320 104 67 0,000 0,15211334 0,16101394 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15211334 0,16094314 ! activation of immune response GO:0002253 105 67 0,000 0,15211334 0,16087239 ! amino acid transport GO:0006865 125 68 0,000 0,15420131 0,16300894 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,15420131 0,16293735 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,15420131 0,16286583 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,15420131 0,16279436 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,15420131 0,16272296 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,15420131 0,16265163 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,15628421 0,16477643 ! negative regulation of cell size GO:0045792 134 69 0,000 0,15628421 0,16470426 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,15628421 0,16463214 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,15628421 0,1645601 ! urogenital system development GO:0001655 137 69 0,000 0,15628421 0,16448811 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,15628421 0,16441619 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,15628421 0,16434433 ! antigen processing and presentation GO:0019882 104 69 0,000 0,15628421 0,16427253 ! appendage morphogenesis GO:0035107 135 70 0,000 0,15836205 0,16638389 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,16043485 0,1684881 ! reproductive structure development GO:0048608 113 71 0,000 0,16043485 0,16841459 ! appendage development GO:0048736 136 71 0,000 0,16043485 0,16834114 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,16043485 0,16826776 ! B cell activation GO:0042113 160 71 0,000 0,16043485 0,16819444 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,16043485 0,16812119 ! regulation of immune effector process GO:0002697 137 71 0,000 0,16043485 0,16804799 ! acute inflammatory response GO:0002526 113 72 0,000 0,1625026 0,1701398 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,1625026 0,1700658 ! carbohydrate transport GO:0008643 110 72 0,000 0,1625026 0,16999185 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,1625026 0,16991798 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,1625026 0,16984416 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,1625026 0,16977041 ! learning or memory GO:0007611 147 73 0,000 0,16456534 0,17185078 ! regulation of blood pressure GO:0008217 125 73 0,000 0,16456534 0,17177623 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,16456534 0,17170173 ! fertilization GO:0009566 90 73 0,000 0,16456534 0,17162731 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,16662306 0,17369804 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,16662306 0,17362281 ! neurotransmitter transport GO:0006836 123 74 0,000 0,16662306 0,17354765 ! meiosis GO:0007126 121 74 0,000 0,16662306 0,17347256 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,16662306 0,17339752 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,16662306 0,17332256 ! eye development GO:0001654 143 74 0,000 0,16662306 0,17324766 ! organelle localization GO:0051640 136 74 0,000 0,16662306 0,17317282 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,16867578 0,17523054 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,16867578 0,17515491 ! meiotic cell cycle GO:0051321 122 75 0,000 0,16867578 0,17507935 ! rhythmic process GO:0048511 128 75 0,000 0,16867578 0,17500385 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,16867578 0,17492842 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,17072351 0,17697577 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,17072351 0,17689956 ! defense response to bacterium GO:0042742 89 76 0,000 0,17072351 0,1768234 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,17072351 0,17674732 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,17072351 0,1766713 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,17276627 0,17870836 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,17276627 0,17863156 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,17276627 0,17855483 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,17276627 0,17847816 ! blood coagulation GO:0007596 146 78 0,000 0,17480406 0,18050582 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,17480406 0,18042839 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,1768369 0,18244836 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,1768369 0,18237016 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,1768369 0,18229202 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,1768369 0,18221396 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,1768369 0,18213595 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,1788648 0,18414579 ! response to metal ion GO:0010038 140 80 0,000 0,1788648 0,18406703 ! muscle cell differentiation GO:0042692 159 80 0,000 0,1788648 0,18398833 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,1788648 0,18390971 ! protein import into nucleus GO:0006606 158 80 0,000 0,1788648 0,18383115 ! inorganic anion transport GO:0015698 138 80 0,000 0,1788648 0,18375265 ! T cell activation GO:0042110 168 81 0,000 0,18088777 0,18575159 ! digestion GO:0007586 112 81 0,000 0,18088777 0,18567235 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,18088777 0,18559317 ! nuclear import GO:0051170 161 81 0,000 0,18088777 0,18551406 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,18088777 0,18543502 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,18290583 0,18742395 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,18290583 0,18734416 ! response to drug GO:0042493 143 82 0,000 0,18290583 0,18726444 ! response to nutrient GO:0007584 125 82 0,000 0,18290583 0,18718478 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,18290583 0,1871052 ! regulation of lyase activity GO:0051339 160 83 0,000 0,18491898 0,18908418 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,18692724 0,19105647 ! hemostasis GO:0007599 158 84 0,000 0,18692724 0,19097534 ! negative regulation of growth GO:0045926 155 84 0,000 0,18692724 0,19089428 ! regulation of ligase activity GO:0051340 142 84 0,000 0,18692724 0,19081329 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,18692724 0,19073237 ! response to unfolded protein GO:0006986 131 85 0,000 0,18893061 0,19269481 ! nucleosome assembly GO:0006334 122 85 0,000 0,18893061 0,19261316 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,18893061 0,19253158 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,19092912 0,1944858 ! response to inorganic substance GO:0010035 153 86 0,000 0,19092912 0,1944035 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,19092912 0,19432126 ! chromatin assembly GO:0031497 124 86 0,000 0,19092912 0,19423909 ! tube morphogenesis GO:0035239 176 86 0,000 0,19092912 0,194157 ! mitochondrion organization GO:0007005 148 86 0,000 0,19092912 0,19407497 ! alcohol catabolic process GO:0046164 130 86 0,000 0,19092912 0,19399301 ! amine transport GO:0015837 155 86 0,000 0,19092912 0,19391113 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,19292277 0,19585324 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,19292277 0,19577064 ! protein localization in nucleus GO:0034504 176 87 0,000 0,19292277 0,1956881 ! cellular respiration GO:0045333 135 88 0,000 0,19491157 0,1976221 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,19491157 0,19753885 ! regulation of neurological system process GO:0031644 148 88 0,000 0,19491157 0,19745568 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,19491157 0,19737257 ! cellular defense response GO:0006968 114 89 0,000 0,19689554 0,19929771 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,19887468 0,20121635 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,19887468 0,20113177 ! sex differentiation GO:0007548 145 90 0,000 0,19887468 0,20104726 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,19887468 0,20096282 ! sterol metabolic process GO:0016125 152 91 0,000 0,20084901 0,20287268 ! response to protein stimulus GO:0051789 149 91 0,000 0,20084901 0,20278755 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,20084901 0,20270248 ! regulation of defense response GO:0031347 149 92 0,000 0,20281854 0,20460437 ! nucleosome organization GO:0034728 138 92 0,000 0,20281854 0,20451862 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,20281854 0,20443293 ! vitamin metabolic process GO:0006766 139 92 0,000 0,20281854 0,20434733 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,20478329 0,20624051 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,20478329 0,20615422 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,20478329 0,206068 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,20674325 0,20795329 ! female pregnancy GO:0007565 164 94 0,000 0,20674325 0,20786639 ! forebrain development GO:0030900 188 95 0,000 0,20869845 0,20974456 ! leukocyte differentiation GO:0002521 202 96 0,000 0,2106489 0,21161639 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,2106489 0,21152807 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,2106489 0,21143982 ! positive regulation of immune response GO:0050778 156 96 0,000 0,2106489 0,21135165 ! detection of stimulus GO:0051606 151 96 0,000 0,2106489 0,21126355 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,21259461 0,21312609 ! hormone metabolic process GO:0042445 157 97 0,000 0,21259461 0,21303733 ! response to virus GO:0009615 160 98 0,000 0,21453558 0,21489284 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,21453558 0,21480341 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,21453558 0,21471406 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,21647183 0,21656184 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,21647183 0,21647183