pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6893-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 6,000 2,915E-08 7,122E-05 ! interphase of mitotic cell cycle GO:0051329 224 98 6,000 1,261E-06 1,54E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 4,054E-06 3,301E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 5,526E-06 3,375E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 5,686E-06 2,778E-03 ! response to metal ion GO:0010038 158 84 5,000 7,404E-06 3,015E-03 ! response to calcium ion GO:0051592 94 49 4,000 7,586E-06 2,647E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 4,000 8,391E-06 2,562E-03 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 8,739E-06 2,372E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 9,061E-06 2,214E-03 ! response to inorganic substance GO:0010035 173 90 5,000 1,103E-05 2,451E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 1,219E-05 2,482E-03 GO:0045936|negative regulation of phosphate metabolic process, ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,354E-05 2,544E-03 ! pyrimidine base metabolic process GO:0006206 22 9 2,000 1,354E-05 2,362E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 1,926E-05 3,137E-03 ! nucleobase biosynthetic process GO:0046112 26 10 2,000 1,926E-05 2,94E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,926E-05 2,768E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,637E-05 3,579E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,637E-05 3,391E-03 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 22 12 2,000 3,502E-05 4,278E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 37 12 2,000 3,502E-05 4,074E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 3,502E-05 3,889E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell growth GO:0030308 142 67 4,000 3,545E-05 3,766E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 4,089E-05 4,162E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 4,089E-05 3,996E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 4,384E-05 4,119E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 2,000 4,534E-05 4,103E-03 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 2,000 4,534E-05 3,956E-03 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 145 71 4,000 4,695E-05 3,955E-03 ! meiosis I GO:0007127 74 38 3,000 5,715E-05 4,654E-03 ! regulation of protein stability GO:0031647 77 38 3,000 5,715E-05 4,504E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 5,732E-05 4,376E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 5,747E-05 4,255E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 5,747E-05 4,13E-03 ! regulation of skeletal muscle tissue development GO:0048641 35 15 2,000 7,155E-05 4,994E-03 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 2,000 7,155E-05 4,855E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 7,155E-05 4,724E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 2,000 8,77E-05 5,638E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 8,77E-05 5,494E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! nucleobase metabolic process GO:0009112 43 17 2,000 1,061E-04 6,478E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,061E-04 6,32E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,061E-04 6,169E-03 ! negative regulation of growth GO:0045926 168 85 4,000 1,111E-04 6,314E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 1,119E-04 6,215E-03 ! epidermis morphogenesis GO:0048730 43 18 2,000 1,268E-04 6,882E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 1,268E-04 6,732E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 2,000 1,268E-04 6,589E-03 ! regulation of BMP signaling pathway GO:0030510 33 18 2,000 1,268E-04 6,452E-03 ! regulation of ossification GO:0030278 123 50 3,000 1,693E-04 8,442E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,757E-04 8,583E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,757E-04 8,414E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,757E-04 8,252E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,757E-04 8,097E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 2,041E-04 9,234E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 2,041E-04 9,066E-03 ! regulation of neuron apoptosis GO:0043523 117 53 3,000 2,125E-04 9,272E-03 ! cartilage development GO:0051216 99 53 3,000 2,125E-04 9,11E-03 ! reciprocal meiotic recombination GO:0007131 44 22 2,000 2,354E-04 9,914E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 2,354E-04 9,746E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 2,354E-04 9,584E-03 ! cell aging GO:0007569 48 22 2,000 2,354E-04 9,426E-03 ! renal system process GO:0003014 42 22 2,000 2,354E-04 9,274E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 2,354E-04 9,127E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! peptidyl-serine modification GO:0018209 50 22 2,000 2,354E-04 8,985E-03 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 2,000 2,354E-04 8,846E-03 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 3,000 2,454E-04 9,085E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 2,696E-04 9,83E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 2,000 2,696E-04 9,685E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,696E-04 9,545E-03 ! regulation of bone remodeling GO:0046850 143 57 3,000 2,818E-04 9,836E-03 ! positive regulation of muscle development GO:0048636 15 5 1,000 2,992E-04 0,01029646 GO:0045844|positive regulation of striated muscle development, ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,992E-04 0,01015345 ! Notch receptor processing GO:0007220 11 5 1,000 2,992E-04 0,01001436 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,992E-04 9,879E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,992E-04 9,747E-03 ! peptidyl-histidine phosphorylation GO:0018106 10 5 1,000 2,992E-04 9,619E-03 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 2,992E-04 9,494E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,992E-04 9,372E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,992E-04 9,254E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,992E-04 9,138E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 2,992E-04 9,025E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,992E-04 8,915E-03 ! stem cell division GO:0017145 11 5 1,000 2,992E-04 8,808E-03 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 2,992E-04 8,703E-03 ! aging GO:0007568 112 58 3,000 3,014E-04 8,663E-03 ! regulation of tissue remodeling GO:0034103 146 58 3,000 3,014E-04 8,562E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 3,068E-04 8,616E-03 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 2,000 3,068E-04 8,518E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 3,473E-04 9,532E-03 ! regulation of behavior GO:0050795 48 25 2,000 3,473E-04 9,426E-03 ! leukocyte homeostasis GO:0001776 50 25 2,000 3,473E-04 9,323E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 3,91E-04 0,01038215 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 2,000 3,91E-04 0,01027052 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! regulation of chromosome organization GO:0033044 49 27 2,000 4,381E-04 0,01138513 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 4,381E-04 0,01126528 ! establishment of spindle localization GO:0051293 16 6 1,000 4,472E-04 0,01138112 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 19 6 1,000 4,472E-04 0,01126379 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 4,472E-04 0,01114885 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 4,472E-04 0,01103624 ! neutrophil homeostasis GO:0001780 11 6 1,000 4,472E-04 0,01092588 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,472E-04 0,0108177 ! triglyceride catabolic process GO:0019433 10 6 1,000 4,472E-04 0,01071164 ! negative regulation of B cell activation GO:0050869 14 6 1,000 4,472E-04 0,01060765 ! nucleoside monophosphate metabolic process GO:0009123 117 65 3,000 4,668E-04 0,01096415 ! negative regulation of protein modification process GO:0031400 66 28 2,000 4,887E-04 0,01136928 ! fat cell differentiation GO:0045444 57 28 2,000 4,887E-04 0,01126202 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 5,428E-04 0,01239373 ! negative regulation of neuron apoptosis GO:0043524 69 29 2,000 5,428E-04 0,01227897 ! urogenital system development GO:0001655 149 69 3,000 5,859E-04 0,01313063 ! homeostasis of number of cells GO:0048872 131 69 3,000 5,859E-04 0,01301126 ! prostate gland development GO:0030850 14 7 1,000 6,239E-04 0,01373033 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,239E-04 0,01360773 ! neuron adhesion GO:0007158 14 7 1,000 6,239E-04 0,01348731 ! pericardium development GO:0060039 16 7 1,000 6,239E-04 0,013369 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,239E-04 0,01325275 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 6,239E-04 0,0131385 ! glycerol ether catabolic process GO:0044269 12 7 1,000 6,239E-04 0,01302621 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 6,239E-04 0,01291581 ! B cell lineage commitment GO:0002326 21 7 1,000 6,239E-04 0,01280728 ! T cell lineage commitment GO:0002360 16 7 1,000 6,239E-04 0,01270055 ! peptidyl-histidine modification GO:0018202 17 7 1,000 6,239E-04 0,01259559 ! axonal fasciculation GO:0007413 19 7 1,000 6,239E-04 0,01249235 ! peptidyl-threonine modification GO:0018210 26 7 1,000 6,239E-04 0,01239078 ! diuresis GO:0030146 12 7 1,000 6,239E-04 0,01229086 GO:0030147|natriuresis, ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 6,239E-04 0,01219253 ! cell junction assembly GO:0034329 85 31 2,000 6,624E-04 0,01284267 ! male gonad development GO:0008584 56 31 2,000 6,624E-04 0,01274155 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 6,624E-04 0,01264201 ! spindle organization GO:0007051 50 32 2,000 7,279E-04 0,01378569 ! metanephros development GO:0001656 81 32 2,000 7,279E-04 0,01367965 ! response to mechanical stimulus GO:0009612 60 32 2,000 7,279E-04 0,01357522 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 7,632E-04 0,01412554 ! leukocyte chemotaxis GO:0030595 55 33 2,000 7,975E-04 0,01464873 GO:0060326|cell chemotaxis, ! reproductive structure development GO:0048608 131 75 3,000 8,028E-04 0,01463584 ! phosphoinositide-mediated signaling GO:0048015 141 75 3,000 8,028E-04 0,01452743 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 8,288E-04 0,01488757 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 8,288E-04 0,0147789 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 8,288E-04 0,01467181 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,288E-04 0,01456626 ! glycerolipid catabolic process GO:0046503 14 8 1,000 8,288E-04 0,01446221 ! pigment granule organization GO:0048753 17 8 1,000 8,288E-04 0,01435964 ! ER overload response GO:0006983 13 8 1,000 8,288E-04 0,01425852 ! regulation of pigmentation during development GO:0048070 25 8 1,000 8,288E-04 0,01415881 ! melanin metabolic process GO:0006582 17 8 1,000 8,288E-04 0,01406048 ! macrophage activation GO:0042116 13 8 1,000 8,288E-04 0,01396352 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,288E-04 0,01386788 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,288E-04 0,01377354 ! response to UV-B GO:0010224 17 8 1,000 8,288E-04 0,01368047 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 8,288E-04 0,01358866 ! myeloid cell homeostasis GO:0002262 15 8 1,000 8,288E-04 0,01349807 ! regulation of Rac protein signal transduction GO:0035020 18 8 1,000 8,288E-04 0,01340867 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 1,000 8,288E-04 0,01332046 ! regulation of blood pressure GO:0008217 134 76 3,000 8,438E-04 0,01347265 ! post-embryonic development GO:0009791 76 34 2,000 8,711E-04 0,0138194 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 8,711E-04 0,01373024 ! DNA damage checkpoint GO:0000077 78 35 2,000 9,49E-04 0,0148609 ! regulation of striated muscle tissue development GO:0016202 81 35 2,000 9,49E-04 0,01476624 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 3,000 9,755E-04 0,01508373 ! regulation of muscle development GO:0048634 82 36 2,000 1,031E-03 0,01584175 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 2,000 1,031E-03 0,01574274 ! neutral lipid catabolic process GO:0046461 14 9 1,000 1,062E-03 0,01611025 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,062E-03 0,0160108 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 1,062E-03 0,01591258 ! T cell selection GO:0045058 27 9 1,000 1,062E-03 0,01581555 ! mannose metabolic process GO:0006013 13 9 1,000 1,062E-03 0,0157197 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,062E-03 0,015625 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 1,062E-03 0,01553144 ! renal water homeostasis GO:0003091 15 9 1,000 1,062E-03 0,01543899 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,062E-03 0,01534764 ! regulation of synaptogenesis GO:0051963 15 9 1,000 1,062E-03 0,01525736 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,062E-03 0,01516813 ! meiosis GO:0007126 143 81 3,000 1,071E-03 0,01521223 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 3,000 1,071E-03 0,0151243 ! cell junction organization GO:0034330 96 37 2,000 1,117E-03 0,01568976 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,117E-03 0,01560011 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,117E-03 0,01551147 ! meiotic cell cycle GO:0051321 144 82 3,000 1,121E-03 0,01547427 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 1,173E-03 0,01609747 GO:0045937|positive regulation of phosphate metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 2,000 1,208E-03 0,01649192 ! regulation of ligase activity GO:0051340 147 84 3,000 1,226E-03 0,01664324 ! regulation of developmental growth GO:0048638 16 10 1,000 1,322E-03 0,01784766 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,322E-03 0,01774959 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,322E-03 0,0176526 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 1,322E-03 0,01755666 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 1,000 1,322E-03 0,01746176 ! B cell proliferation GO:0042100 19 10 1,000 1,322E-03 0,01736788 ! motor axon guidance GO:0008045 22 10 1,000 1,322E-03 0,01727501 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 1,322E-03 0,01718312 ! protein sumoylation GO:0016925 17 10 1,000 1,322E-03 0,0170922 ! multicellular organismal water homeostasis GO:0050891 16 10 1,000 1,322E-03 0,01700224 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,322E-03 0,01691323 ! natural killer cell mediated immunity GO:0002228 19 10 1,000 1,322E-03 0,01682514 GO:0042267|natural killer cell mediated cytotoxicity, ! response to nicotine GO:0035094 20 10 1,000 1,322E-03 0,01673796 ! mitochondrion organization GO:0007005 159 87 3,000 1,397E-03 0,01758737 ! nucleus organization GO:0006997 73 40 2,000 1,404E-03 0,01758722 ! positive regulation of protein modification process GO:0031401 156 90 3,000 1,583E-03 0,01972879 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,61E-03 0,01996945 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,61E-03 0,01986859 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,61E-03 0,01976875 GO:0010812|negative regulation of cell-substrate adhesion, ! behavioral fear response GO:0001662 27 11 1,000 1,61E-03 0,01966991 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 1,61E-03 0,01957205 ! alpha-beta T cell activation GO:0046631 26 11 1,000 1,61E-03 0,01947516 ! thymus development GO:0048538 29 11 1,000 1,61E-03 0,01937922 ! oocyte development GO:0048599 20 11 1,000 1,61E-03 0,01928422 ! ribonucleoside metabolic process GO:0009119 64 42 2,000 1,618E-03 0,019282 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,618E-03 0,0191884 ! gland development GO:0048732 220 91 3,000 1,649E-03 0,01945603 ! regulation of cell adhesion GO:0030155 241 92 3,000 1,716E-03 0,02015638 ! striated muscle cell differentiation GO:0051146 91 43 2,000 1,732E-03 0,02024946 ! development of primary male sexual characteristics GO:0046546 80 43 2,000 1,732E-03 0,02015304 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,732E-03 0,02005753 ! neuron migration GO:0001764 85 43 2,000 1,732E-03 0,01996291 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 1,852E-03 0,02123708 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 1,852E-03 0,02113784 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,925E-03 0,02187752 ! T cell homeostasis GO:0043029 28 12 1,000 1,925E-03 0,02177623 ! oocyte differentiation GO:0009994 21 12 1,000 1,925E-03 0,02167588 ! leukocyte mediated cytotoxicity GO:0001909 28 12 1,000 1,925E-03 0,02157645 ! regulation of synapse organization GO:0050807 18 12 1,000 1,925E-03 0,02147793 ! sex differentiation GO:0007548 171 96 3,000 2,006E-03 0,02227332 ! leukocyte migration GO:0050900 75 46 2,000 2,105E-03 0,02327167 ! negative regulation of cell migration GO:0030336 122 46 2,000 2,105E-03 0,02316685 ! pigmentation GO:0043473 103 46 2,000 2,105E-03 0,02306296 ! cGMP metabolic process GO:0046068 18 13 1,000 2,267E-03 0,02472651 GO:0006182|cGMP biosynthetic process, ! cartilage condensation GO:0001502 22 13 1,000 2,267E-03 0,02461662 ! endocrine pancreas development GO:0031018 25 13 1,000 2,267E-03 0,0245077 ! plasma membrane organization GO:0007009 27 13 1,000 2,267E-03 0,02439973 ! membrane protein proteolysis GO:0033619 33 13 1,000 2,267E-03 0,02429272 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 2,267E-03 0,02418663 ! gland morphogenesis GO:0022612 31 13 1,000 2,267E-03 0,02408147 ! spleen development GO:0048536 24 13 1,000 2,267E-03 0,02397723 ! digestive tract morphogenesis GO:0048546 31 13 1,000 2,267E-03 0,02387388 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of synapse structure and activity GO:0050803 19 13 1,000 2,267E-03 0,02377141 ! positive regulation of cell cycle GO:0045787 96 48 2,000 2,379E-03 0,02484121 ! positive regulation of defense response GO:0031349 88 48 2,000 2,379E-03 0,0247355 ! cellular component disassembly GO:0022411 89 48 2,000 2,379E-03 0,02463069 ! male sex differentiation GO:0046661 93 48 2,000 2,379E-03 0,02452676 ! regulation of inflammatory response GO:0050727 84 48 2,000 2,379E-03 0,02442371 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 2,524E-03 0,02580341 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,524E-03 0,02569589 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 2,635E-03 0,02671561 GO:0046579|positive regulation of Ras protein signal transduction, ! hair follicle morphogenesis GO:0031069 27 14 1,000 2,635E-03 0,02660521 ! fear response GO:0042596 34 14 1,000 2,635E-03 0,02649573 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 2,635E-03 0,02638714 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 37 14 1,000 2,635E-03 0,02627943 ! response to gamma radiation GO:0010332 30 14 1,000 2,635E-03 0,02617261 ! activation of caspase activity GO:0006919 95 50 2,000 2,675E-03 0,02645445 ! negative regulation of immune system process GO:0002683 101 51 2,000 2,83E-03 0,02788187 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 3,03E-03 0,02972732 ! glycoprotein catabolic process GO:0006516 33 15 1,000 3,03E-03 0,02960841 ! regulation of vasodilation GO:0042312 27 15 1,000 3,03E-03 0,02949045 ! water homeostasis GO:0030104 28 15 1,000 3,03E-03 0,02937342 ! cell killing GO:0001906 32 15 1,000 3,03E-03 0,02925732 ! lymphocyte homeostasis GO:0002260 33 15 1,000 3,03E-03 0,02914214 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 3,158E-03 0,0302584 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 125 54 2,000 3,331E-03 0,03178485 ! regulation of muscle contraction GO:0006937 94 54 2,000 3,331E-03 0,03166118 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 3,331E-03 0,03153846 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 3,45E-03 0,03254416 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 3,45E-03 0,03241899 ! neuron recognition GO:0008038 40 16 1,000 3,45E-03 0,03229478 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 3,45E-03 0,03217152 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,45E-03 0,03204919 ! response to UV GO:0009411 120 55 2,000 3,509E-03 0,03246882 ! negative regulation of cell motion GO:0051271 142 55 2,000 3,509E-03 0,0323463 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,882E-03 0,03565211 GO:0010952|positive regulation of peptidase activity, ! metencephalon development GO:0022037 32 17 1,000 3,896E-03 0,03564887 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,896E-03 0,03551585 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 3,896E-03 0,03538382 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,896E-03 0,03525277 ! regulation of protein binding GO:0043393 33 17 1,000 3,896E-03 0,03512269 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 3,896E-03 0,03499356 ! regulation of viral genome replication GO:0045069 30 18 1,000 4,367E-03 0,03908176 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 4,367E-03 0,03893912 ! defense response to virus GO:0051607 43 18 1,000 4,367E-03 0,03879753 ! positive regulation of synaptic transmission GO:0050806 35 18 1,000 4,367E-03 0,03865695 ! DNA catabolic process GO:0006308 94 60 2,000 4,485E-03 0,03955953 ! kidney development GO:0001822 133 60 2,000 4,485E-03 0,03941723 ! regulation of heart contraction GO:0008016 123 61 2,000 4,699E-03 0,0411417 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 4,699E-03 0,04099477 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 4,863E-03 0,04228273 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,863E-03 0,04213279 ! neuromuscular junction development GO:0007528 43 19 1,000 4,863E-03 0,04198391 ! visual learning GO:0008542 38 19 1,000 4,863E-03 0,04183608 ! cellular pigmentation GO:0033059 37 19 1,000 4,863E-03 0,04168928 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 1,000 4,863E-03 0,04154352 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 4,918E-03 0,04185993 ! nucleoside metabolic process GO:0009116 91 62 2,000 4,918E-03 0,04171458 ! regulation of homeostatic process GO:0032844 148 62 2,000 4,918E-03 0,04157024 ! skeletal system morphogenesis GO:0048705 118 63 2,000 5,143E-03 0,04332378 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 5,374E-03 0,04511662 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 5,384E-03 0,04504769 ! skin development GO:0043588 42 20 1,000 5,384E-03 0,04489394 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,384E-03 0,04474124 ! forelimb morphogenesis GO:0035136 35 20 1,000 5,384E-03 0,04458958 ! pancreas development GO:0031016 40 20 1,000 5,384E-03 0,04443894 ! cellular response to unfolded protein GO:0034620 35 20 1,000 5,384E-03 0,04428931 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 5,384E-03 0,04414069 ! body fluid secretion GO:0007589 33 20 1,000 5,384E-03 0,04399306 ! positive regulation of neurological system process GO:0031646 39 20 1,000 5,384E-03 0,04384642 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 5,384E-03 0,04370075 ! negative regulation of translation GO:0017148 32 20 1,000 5,384E-03 0,04355604 ! lymphocyte mediated immunity GO:0002449 122 65 2,000 5,612E-03 0,04524434 ! ear development GO:0043583 114 66 2,000 5,855E-03 0,04705359 ! gonad development GO:0008406 115 66 2,000 5,855E-03 0,04689932 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 5,855E-03 0,04674605 ! ovarian follicle development GO:0001541 39 21 1,000 5,93E-03 0,04718587 ! smooth muscle contraction GO:0006939 48 21 1,000 5,93E-03 0,04703267 ! collagen fibril organization GO:0030199 62 21 1,000 5,93E-03 0,04688046 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 5,93E-03 0,04672923 ! chromosome segregation GO:0007059 127 67 2,000 6,105E-03 0,04795759 ! hindlimb morphogenesis GO:0035137 47 22 1,000 6,499E-03 0,05088836 ! glutamate signaling pathway GO:0007215 48 22 1,000 6,499E-03 0,05072578 ! ureteric bud development GO:0001657 50 22 1,000 6,499E-03 0,05056423 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 6,499E-03 0,05040371 ! G1 phase GO:0051318 44 22 1,000 6,499E-03 0,0502442 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,499E-03 0,0500857 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 6,499E-03 0,0499282 ! response to cytokine stimulus GO:0034097 69 22 1,000 6,499E-03 0,04977169 ! gut development GO:0048565 44 22 1,000 6,499E-03 0,04961615 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,499E-03 0,04946158 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 6,624E-03 0,05025475 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 6,624E-03 0,05009916 ! germ cell development GO:0007281 133 70 2,000 6,893E-03 0,05197197 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 6,893E-03 0,05181206 ! regeneration GO:0031099 42 23 1,000 7,092E-03 0,05314895 ! visual behavior GO:0007632 46 23 1,000 7,092E-03 0,05298641 ! response to ethanol GO:0045471 47 23 1,000 7,092E-03 0,05282487 ! regulation of bone mineralization GO:0030500 54 23 1,000 7,092E-03 0,05266431 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 7,168E-03 0,053065 ! actin filament organization GO:0007015 167 72 2,000 7,45E-03 0,05498402 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 7,45E-03 0,05481841 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 7,45E-03 0,05465379 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,709E-03 0,05638788 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 7,709E-03 0,05621956 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 7,709E-03 0,05605224 ! sex determination GO:0007530 48 24 1,000 7,709E-03 0,05588591 ! regulation of viral reproduction GO:0050792 41 24 1,000 7,709E-03 0,05572057 ! oogenesis GO:0048477 44 24 1,000 7,709E-03 0,0555562 ! humoral immune response GO:0006959 115 73 2,000 7,738E-03 0,05559936 ! regulation of caspase activity GO:0043281 136 74 2,000 8,033E-03 0,05754765 ! leukocyte mediated immunity GO:0002443 136 75 2,000 8,334E-03 0,05953126 ! eye development GO:0001654 155 75 2,000 8,334E-03 0,05935769 ! axon guidance GO:0007411 162 75 2,000 8,334E-03 0,05918514 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 8,349E-03 0,05912313 ! vasculogenesis GO:0001570 49 25 1,000 8,349E-03 0,05895225 ! lymphocyte proliferation GO:0046651 55 25 1,000 8,349E-03 0,05878236 ! regulation of biomineral formation GO:0070167 56 25 1,000 8,349E-03 0,05861345 ! cell-matrix adhesion GO:0007160 181 76 2,000 8,642E-03 0,06049191 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 8,956E-03 0,06251368 ! positive regulation of ligase activity GO:0051351 130 77 2,000 8,956E-03 0,06233557 ! myelination GO:0042552 50 26 1,000 9,013E-03 0,06255021 ! molting cycle process GO:0022404 52 26 1,000 9,013E-03 0,06237301 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! multicellular organismal response to stress GO:0033555 61 26 1,000 9,013E-03 0,06219682 ! positive regulation of nuclear division GO:0051785 41 26 1,000 9,013E-03 0,06202161 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 9,013E-03 0,0618474 ! neural tube closure GO:0001843 58 26 1,000 9,013E-03 0,06167415 GO:0060606|tube closure, ! regulation of synaptic transmission GO:0050804 159 79 2,000 9,605E-03 0,06554371 ! tube lumen formation GO:0035148 59 27 1,000 9,699E-03 0,06599853 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 9,699E-03 0,0658152 ! mitochondrial membrane organization GO:0007006 60 27 1,000 9,699E-03 0,06563288 ! response to toxin GO:0009636 49 27 1,000 9,699E-03 0,06545158 ! leukocyte proliferation GO:0070661 59 27 1,000 9,699E-03 0,06527127 GO:0032943|mononuclear cell proliferation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 9,939E-03 0,06670751 ! development of primary sexual characteristics GO:0045137 143 80 2,000 9,939E-03 0,06652475 ! muscle cell differentiation GO:0042692 178 81 2,000 0,01028031 0,06861968 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01040697 0,06927579 ! dendrite development GO:0016358 67 28 1,000 0,01040697 0,06908754 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 1,000 0,01040697 0,06890032 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01062813 0,07017437 ! cell-substrate adhesion GO:0031589 189 82 2,000 0,01062813 0,06998522 ! protein import into nucleus GO:0006606 174 82 2,000 0,01062813 0,06979709 ! nuclear import GO:0051170 177 83 2,000 0,0109827 0,07193227 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01113764 0,07275203 ! primary neural tube formation GO:0014020 61 29 1,000 0,01113764 0,07255803 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01113764 0,07236505 ! response to nutrient GO:0007584 135 84 2,000 0,01134405 0,07351065 ! negative regulation of transport GO:0051051 164 85 2,000 0,0117122 0,0756955 ! regulation of neuron differentiation GO:0045664 187 85 2,000 0,0117122 0,07549577 ! regulation of transmission of nerve impulse GO:0051969 167 85 2,000 0,0117122 0,0752971 ! complement activation, classical pathway GO:0006958 51 30 1,000 0,01189028 0,07624135 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01189028 0,07604177 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01189028 0,07584323 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 0,01189028 0,07564572 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01189028 0,07544924 ! ovulation cycle process GO:0022602 55 31 1,000 0,01266462 0,08015457 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01266462 0,07994745 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01266462 0,0797414 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01266462 0,07953641 GO:0008366|axon ensheathment, ! response to heat GO:0009408 54 31 1,000 0,01266462 0,07933247 ! tube morphogenesis GO:0035239 194 89 2,000 0,01325317 0,08280687 ! protein localization in nucleus GO:0034504 192 89 2,000 0,01325317 0,08259563 ! regulation of neurological system process GO:0031644 175 89 2,000 0,01325317 0,08238546 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 0,0134604 0,0834613 ! hexose biosynthetic process GO:0019319 53 32 1,000 0,0134604 0,08325001 ! ovulation cycle GO:0042698 57 32 1,000 0,0134604 0,08303978 ! peripheral nervous system development GO:0007422 68 32 1,000 0,0134604 0,08283061 ! hindbrain development GO:0030902 65 32 1,000 0,0134604 0,08262249 ! myeloid leukocyte activation GO:0002274 53 32 1,000 0,0134604 0,08241542 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01365559 0,08340153 ! ossification GO:0001503 205 91 2,000 0,01406492 0,0856873 ! triglyceride metabolic process GO:0006641 46 33 1,000 0,01427736 0,08676515 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01427736 0,08654985 ! bone development GO:0060348 206 92 2,000 0,01448117 0,08756809 ! response to hydrogen peroxide GO:0042542 56 34 1,000 0,01511525 0,09117667 ! regulation of membrane potential GO:0042391 179 94 2,000 0,01533449 0,09227133 ! regulation of defense response GO:0031347 171 95 2,000 0,01577158 0,09466822 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01597381 0,09564711 ! response to protein stimulus GO:0051789 158 96 2,000 0,01621564 0,0968577 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01621564 0,09662146 ! regulation of protein localization GO:0032880 188 97 2,000 0,01666667 0,09906736 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,0168528 0,09993055 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,0168528 0,09968858 ! positive regulation of cell development GO:0010720 85 36 1,000 0,0168528 0,09944779 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,0168528 0,09920816 ! forebrain development GO:0030900 210 98 2,000 0,0171247 0,10056644 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01775196 0,10400008 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01775196 0,10375128 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01775196 0,10350366 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01775196 0,10325723 ! odontogenesis GO:0042476 74 37 1,000 0,01775196 0,10301196 ! female gonad development GO:0008585 71 37 1,000 0,01775196 0,10276786 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,01867105 0,10783302 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 0,01867105 0,1075787 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01867105 0,10732557 ! pigment metabolic process GO:0042440 87 38 1,000 0,01867105 0,10707363 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01867105 0,10682287 ! neural tube formation GO:0001841 79 38 1,000 0,01867105 0,10657329 ! negative regulation of binding GO:0051100 71 39 1,000 0,01960982 0,11167083 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01960982 0,11141113 ! glucan metabolic process GO:0044042 64 39 1,000 0,01960982 0,11115263 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,02056803 0,11631411 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 0,02056803 0,11604548 ! learning GO:0007612 82 40 1,000 0,02056803 0,1157781 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,02056803 0,11551194 GO:0046660|female sex differentiation, ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02056803 0,115247 ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,02056803 0,11498328 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,02056803 0,11472076 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,02154544 0,11989865 ! mesenchymal cell development GO:0014031 94 41 1,000 0,02154544 0,11962615 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,02154544 0,11935489 ! ear morphogenesis GO:0042471 64 42 1,000 0,02254181 0,12459195 ! organic ether metabolic process GO:0018904 59 42 1,000 0,02254181 0,1243107 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,02254181 0,12403073 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,02254181 0,123752 ! T cell differentiation GO:0030217 93 42 1,000 0,02254181 0,12347453 ! cytokinesis GO:0000910 84 42 1,000 0,02254181 0,1231983 ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02355691 0,12845875 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,02355691 0,12817265 ! glucose transport GO:0015758 66 43 1,000 0,02355691 0,12788782 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02355691 0,12760426 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,02459049 0,13290834 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,02459049 0,13261494 ! hexose transport GO:0008645 68 44 1,000 0,02459049 0,13232284 GO:0015749|monosaccharide transport, ! phagocytosis GO:0006909 105 44 1,000 0,02459049 0,13203202 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02564233 0,13737768 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02564233 0,13707707 ! B cell differentiation GO:0030183 124 45 1,000 0,02564233 0,13677777 ! female gamete generation GO:0007292 71 45 1,000 0,02564233 0,13647978 ! developmental growth GO:0048589 88 45 1,000 0,02564233 0,13618309 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,0267122 0,14155729 ! cell growth GO:0016049 90 46 1,000 0,0267122 0,14125089 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,0267122 0,14094581 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02727058 0,14358193 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02727058 0,14327316 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02727058 0,1429657 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02727058 0,14265957 ! neuron fate determination GO:0048664 7 5 0,000 0,02727058 0,14235474 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02727058 0,14205121 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02727058 0,14174897 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02727058 0,14144802 ! polyol transport GO:0015791 12 5 0,000 0,02727058 0,14114834 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02727058 0,14084993 ! response to superoxide GO:0000303 10 5 0,000 0,02727058 0,14055278 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02727058 0,14025688 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02727058 0,13996222 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02727058 0,1396688 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02727058 0,13937661 ! female meiosis GO:0007143 10 5 0,000 0,02727058 0,13908563 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02727058 0,13879587 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02727058 0,13850731 ! hypothalamus development GO:0021854 9 5 0,000 0,02727058 0,13821995 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02727058 0,13793378 ! cobalt ion transport GO:0006824 11 5 0,000 0,02727058 0,1376488 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02727058 0,13736499 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02727058 0,13708234 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02727058 0,13680086 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02727058 0,13652053 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02727058 0,13624135 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02727058 0,1359633 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02727058 0,13568639 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02727058 0,13541061 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02727058 0,13513594 ! transposition GO:0032196 9 5 0,000 0,02727058 0,13486238 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02727058 0,13458994 ! negative chemotaxis GO:0050919 16 5 0,000 0,02727058 0,13431858 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02727058 0,13404833 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02727058 0,13377915 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02727058 0,13351106 ! behavioral response to pain GO:0048266 10 5 0,000 0,02727058 0,13324404 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02727058 0,13297808 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02727058 0,13271318 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02727058 0,13244934 ! micturition GO:0060073 9 5 0,000 0,02727058 0,13218654 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02727058 0,13192479 ! copulation GO:0007620 9 5 0,000 0,02727058 0,13166407 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02727058 0,13140437 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02727058 0,1311457 ! bioluminescence GO:0008218 9 5 0,000 0,02727058 0,13088805 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02727058 0,13063141 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02727058 0,13037577 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02727058 0,13012113 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02727058 0,12986748 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02727058 0,12961482 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02727058 0,12936314 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02727058 0,12911244 ! grooming behavior GO:0007625 6 5 0,000 0,02727058 0,1288627 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02727058 0,12861393 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02727058 0,12836612 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02727058 0,12811927 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02727058 0,12787335 ! response to protozoan GO:0001562 13 5 0,000 0,02727058 0,12762839 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02727058 0,12738436 ! lymph vessel development GO:0001945 10 5 0,000 0,02727058 0,12714126 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02727058 0,12689908 ! endochondral ossification GO:0001958 17 5 0,000 0,02727058 0,12665783 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02727058 0,12641749 ! single strand break repair GO:0000012 8 5 0,000 0,02727058 0,12617806 ! parathyroid gland development GO:0060017 14 5 0,000 0,02727058 0,12593954 ! anagen GO:0042640 7 5 0,000 0,02727058 0,12570192 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02727058 0,12546519 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02727058 0,12522936 ! cytokine secretion GO:0050663 15 5 0,000 0,02727058 0,1249944 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02727058 0,12476033 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02727058 0,12452714 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02727058 0,12429481 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02727058 0,12406335 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02727058 0,12383275 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02727058 0,123603 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02727058 0,12337411 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02727058 0,12314606 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02727058 0,12291885 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02727058 0,12269248 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02727058 0,12246694 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02727058 0,12224223 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02727058 0,12201835 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02727058 0,12179528 ! microvillus organization GO:0032528 8 5 0,000 0,02727058 0,12157303 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02727058 0,12135158 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02727058 0,12113094 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02727058 0,1209111 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02727058 0,12069206 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02727058 0,12047381 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02727058 0,12025635 ! polyol catabolic process GO:0046174 9 5 0,000 0,02727058 0,12003967 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02727058 0,11982377 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02727058 0,11960865 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02727058 0,1193943 ! muscle cell migration GO:0014812 8 5 0,000 0,02727058 0,11918071 ! mitochondrial fission GO:0000266 8 5 0,000 0,02727058 0,11896789 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02727058 0,11875583 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02727058 0,11854452 ! mRNA transcription GO:0009299 10 5 0,000 0,02727058 0,11833396 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02727058 0,11812415 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02727058 0,11791508 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02727058 0,11770675 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02727058 0,11749915 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02727058 0,11729228 ! monocyte activation GO:0042117 10 5 0,000 0,02727058 0,11708615 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02727058 0,11688073 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02727058 0,11667604 ! response to food GO:0032094 6 5 0,000 0,02727058 0,11647206 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02727058 0,11626879 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02727058 0,11606623 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02727058 0,11586438 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02727058 0,11566323 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02727058 0,11546277 ! forebrain neuron development GO:0021884 13 5 0,000 0,02727058 0,11526301 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02727058 0,11506393 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02727058 0,11486555 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02727058 0,11466784 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02727058 0,11447082 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02727058 0,11427447 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02727058 0,1140788 ! lipid glycosylation GO:0030259 7 5 0,000 0,02727058 0,11388379 ! nucleobase transport GO:0015851 6 5 0,000 0,02727058 0,11368945 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02727058 0,11349577 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02727058 0,11330275 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02727058 0,11311039 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02727058 0,11291867 ! basic amino acid transport GO:0015802 12 5 0,000 0,02727058 0,11272761 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02727058 0,11253719 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02727058 0,11234742 ! actin nucleation GO:0045010 11 5 0,000 0,02727058 0,11215828 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02727058 0,11196978 ! depurination GO:0045007 5 5 0,000 0,02727058 0,11178191 ! depyrimidination GO:0045008 10 5 0,000 0,02727058 0,11159467 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02727058 0,11140806 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02727058 0,11122207 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02727058 0,1110367 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02727058 0,11085194 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02727058 0,1106678 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02727058 0,11048428 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02727058 0,11030135 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02727058 0,11011904 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02727058 0,10993732 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02727058 0,10975621 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02727058 0,10957569 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02727058 0,10939576 ! response to arsenic GO:0046685 11 5 0,000 0,02727058 0,10921642 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02727058 0,10903767 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02727058 0,10885951 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02727058 0,10868192 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02727058 0,10850492 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02727058 0,10832848 ! response to mercury ion GO:0046689 8 5 0,000 0,02727058 0,10815263 ! response to cadmium ion GO:0046686 7 5 0,000 0,02727058 0,10797734 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02727058 0,10780262 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02727058 0,10762846 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02727058 0,10745487 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02727058 0,10728183 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02727058 0,10710935 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02727058 0,10693743 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02727058 0,10676605 ! decidualization GO:0046697 11 5 0,000 0,02727058 0,10659523 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02727058 0,10642495 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02727058 0,10625521 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02727058 0,10608602 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02727058 0,10591736 ! embryonic cleavage GO:0040016 6 5 0,000 0,02727058 0,10574923 ! peroxisome fission GO:0016559 5 5 0,000 0,02727058 0,10558164 ! histone demethylation GO:0016577 13 5 0,000 0,02727058 0,10541459 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02727058 0,10524805 ! mitotic recombination GO:0006312 9 5 0,000 0,02727058 0,10508205 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02727058 0,10491656 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02727058 0,1047516 ! metaphase plate congression GO:0051310 7 5 0,000 0,02727058 0,10458716 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02727058 0,10442323 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02727058 0,10425981 ! enteric nervous system development GO:0048484 8 5 0,000 0,02727058 0,1040969 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02727058 0,10393451 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02727058 0,10377261 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02727058 0,10361123 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02727058 0,10345034 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02727058 0,10328995 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02727058 0,10313006 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02727058 0,10297066 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02727058 0,10281176 ! metaphase GO:0051323 11 5 0,000 0,02727058 0,10265334 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02727058 0,10249541 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02727058 0,10233797 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02727058 0,10218101 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02727058 0,10202453 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02727058 0,10186853 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02727058 0,101713 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02727058 0,10155795 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02727058 0,10140338 ! response to redox state GO:0051775 6 5 0,000 0,02727058 0,10124927 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02727058 0,10109563 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02727058 0,10094245 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02727058 0,10078974 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02727058 0,10063749 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02727058 0,1004857 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02727058 0,10033436 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02727058 0,10018349 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02727058 0,10003306 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02727058 0,09988309 ! striatum development GO:0021756 14 5 0,000 0,02727058 0,09973356 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02727058 0,09958448 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02727058 0,09943585 ! glial cell migration GO:0008347 10 5 0,000 0,02727058 0,09928766 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02727058 0,09913991 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02727058 0,0989926 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02727058 0,09884572 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02727058 0,09869929 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02727058 0,09855328 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02727058 0,09840771 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02727058 0,09826256 ! neuroprotection GO:0043526 8 5 0,000 0,02727058 0,09811785 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02727058 0,09797356 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02727058 0,09782969 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02727058 0,09768624 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02727058 0,09754322 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02727058 0,09740061 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02727058 0,09725842 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02727058 0,09711664 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02727058 0,09697528 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02727058 0,09683433 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02727058 0,09669378 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02727058 0,09655365 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02727058 0,09641392 ! spindle assembly GO:0051225 6 5 0,000 0,02727058 0,09627459 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02727058 0,09613567 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02727058 0,09599714 ! protein palmitoylation GO:0018345 12 5 0,000 0,02727058 0,09585902 ! drug metabolic process GO:0017144 7 5 0,000 0,02727058 0,09572129 ! organ regeneration GO:0031100 7 5 0,000 0,02727058 0,09558396 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02727058 0,09544702 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02727058 0,09531047 ! neural tube development GO:0021915 91 47 1,000 0,02779987 0,09702154 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,02779987 0,09688314 ! response to insulin stimulus GO:0032868 98 47 1,000 0,02779987 0,09674513 ! mitochondrial transport GO:0006839 94 48 1,000 0,02890511 0,10044833 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,02890511 0,10030565 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02890511 0,10016337 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,03002769 0,10390602 ! regulation of action potential GO:0001508 102 50 1,000 0,0311674 0,10769726 ! endocrine system development GO:0035270 109 50 1,000 0,0311674 0,10754514 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,0311674 0,10739346 GO:0019724|B cell mediated immunity, ! response to temperature stimulus GO:0009266 84 51 1,000 0,03232401 0,11122192 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03232401 0,11106549 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03263525 0,11197739 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03263525 0,11182034 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03263525 0,11166373 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03263525 0,11150756 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03263525 0,11135182 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03263525 0,11119652 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03263525 0,11104165 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03263525 0,11088721 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03263525 0,1107332 ! response to oxygen radical GO:0000305 11 6 0,000 0,03263525 0,11057962 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03263525 0,11042646 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03263525 0,11027373 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03263525 0,11012141 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03263525 0,10996952 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03263525 0,10981805 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03263525 0,10966699 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03263525 0,10951635 ! forebrain regionalization GO:0021871 9 6 0,000 0,03263525 0,10936612 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03263525 0,10921631 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03263525 0,1090669 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03263525 0,1089179 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03263525 0,10876931 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03263525 0,10862112 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03263525 0,10847334 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03263525 0,10832596 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03263525 0,10817897 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03263525 0,10803239 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03263525 0,1078862 ! malate metabolic process GO:0006108 13 6 0,000 0,03263525 0,10774041 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03263525 0,10759501 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03263525 0,10745001 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03263525 0,10730539 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03263525 0,10716116 ! protein refolding GO:0042026 15 6 0,000 0,03263525 0,10701732 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03263525 0,10687387 ! opsonization GO:0008228 8 6 0,000 0,03263525 0,1067308 ! mating behavior GO:0007617 7 6 0,000 0,03263525 0,10658811 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03263525 0,1064458 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03263525 0,10630387 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03263525 0,10616232 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03263525 0,10602115 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03263525 0,10588035 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03263525 0,10573993 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03263525 0,10559987 ! toxin metabolic process GO:0009404 11 6 0,000 0,03263525 0,10546019 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03263525 0,10532088 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03263525 0,10518193 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03263525 0,10504335 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03263525 0,10490514 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03263525 0,10476728 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03263525 0,1046298 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03263525 0,10449267 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03263525 0,1043559 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03263525 0,10421948 ! thymic T cell selection GO:0045061 16 6 0,000 0,03263525 0,10408343 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03263525 0,10394772 ! protein lipoylation GO:0009249 10 6 0,000 0,03263525 0,10381237 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03263525 0,10367738 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03263525 0,10354273 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03263525 0,10340844 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03263525 0,10327449 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03263525 0,10314088 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03263525 0,10300763 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03263525 0,10287471 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03263525 0,10274214 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03263525 0,10260991 ! hyperosmotic response GO:0006972 10 6 0,000 0,03263525 0,10247803 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03263525 0,10234647 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03263525 0,10221526 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03263525 0,10208438 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03263525 0,10195384 ! urea metabolic process GO:0019627 7 6 0,000 0,03263525 0,10182363 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03263525 0,10169375 ! neutrophil activation GO:0042119 7 6 0,000 0,03263525 0,10156421 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03263525 0,10143499 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03263525 0,1013061 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03263525 0,10117754 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03263525 0,10104931 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03263525 0,1009214 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03263525 0,10079381 ! neuron apoptosis GO:0051402 15 6 0,000 0,03263525 0,10066655 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03263525 0,1005396 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03263525 0,10041298 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03263525 0,10028667 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03263525 0,10016068 ! carnitine transport GO:0015879 10 6 0,000 0,03263525 0,10003501 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03263525 0,09990965 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03263525 0,09978461 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03263525 0,09965988 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03263525 0,09953546 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03263525 0,09941135 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03263525 0,09928755 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03263525 0,09916406 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03263525 0,09904087 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03263525 0,09891799 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03263525 0,09879542 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03263525 0,09867315 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,03263525 0,09855118 ! astrocyte development GO:0014002 16 6 0,000 0,03263525 0,09842951 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03263525 0,09830814 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03263525 0,09818707 ! interaction with symbiont GO:0051702 14 6 0,000 0,03263525 0,0980663 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03263525 0,09794583 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03263525 0,09782565 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03263525 0,09770576 ! response to copper ion GO:0046688 10 6 0,000 0,03263525 0,09758617 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03263525 0,09746688 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03263525 0,09734787 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03263525 0,09722915 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03263525 0,09711072 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03263525 0,09699258 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03263525 0,09687473 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03263525 0,09675716 ! hair follicle maturation GO:0048820 8 6 0,000 0,03263525 0,09663988 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03263525 0,09652289 ! Schwann cell development GO:0014044 15 6 0,000 0,03263525 0,09640617 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03263525 0,09628974 ! response to pheromone GO:0019236 6 6 0,000 0,03263525 0,09617359 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03263525 0,09605772 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03263525 0,09594212 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03263525 0,09582681 ! subpallium development GO:0021544 15 6 0,000 0,03263525 0,09571177 ! neural tube patterning GO:0021532 8 6 0,000 0,03263525 0,09559701 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03263525 0,09548252 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03263525 0,09536831 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03263525 0,09525437 ! G2 phase GO:0051319 16 6 0,000 0,03263525 0,0951407 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03263525 0,0950273 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03263525 0,09491417 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03263525 0,09480131 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03263525 0,09468872 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03263525 0,0945764 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03263525 0,09446434 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03263525 0,09435255 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03263525 0,09424102 ! receptor internalization GO:0031623 11 6 0,000 0,03263525 0,09412976 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03263525 0,09401875 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03263525 0,09390801 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03263525 0,09379753 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03263525 0,09368731 ! protein deubiquitination GO:0016579 16 6 0,000 0,03263525 0,09357735 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03263525 0,09346765 ! protein destabilization GO:0031648 9 6 0,000 0,03263525 0,0933582 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03263525 0,09324901 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03263525 0,09314007 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03263525 0,09303139 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03263525 0,09292296 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03263525 0,09281479 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03263525 0,09270686 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03263525 0,09259919 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03263525 0,09249177 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03263525 0,09238459 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03263525 0,09227767 ! neural plate development GO:0001840 9 6 0,000 0,03263525 0,09217099 ! catecholamine transport GO:0051937 9 6 0,000 0,03263525 0,09206455 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03263525 0,09195837 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03263525 0,09185242 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03263525 0,09174672 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03263525 0,09164127 ! maternal placenta development GO:0001893 12 6 0,000 0,03263525 0,09153605 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03263525 0,09143108 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03263525 0,09132635 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03263525 0,09122186 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03263525 0,0911176 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03263525 0,09101359 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03263525 0,09090981 GO:0055081|anion homeostasis, ! response to estrogen stimulus GO:0043627 98 52 1,000 0,03349731 0,09320493 ! Notch signaling pathway GO:0007219 111 52 1,000 0,03349731 0,09309889 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03349731 0,0929931 ! excretion GO:0007588 87 52 1,000 0,03349731 0,09288754 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,03349731 0,09278223 ! positive regulation of growth GO:0045927 96 53 1,000 0,03468707 0,09596887 ! vesicle organization GO:0016050 127 53 1,000 0,03468707 0,09586031 ! synapse organization GO:0050808 102 53 1,000 0,03468707 0,09575199 ! regulation of translational initiation GO:0006446 87 54 1,000 0,03589308 0,09896931 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03589308 0,09885773 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03711514 0,10210842 ! cell recognition GO:0008037 98 55 1,000 0,03711514 0,10199357 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03711514 0,10187897 ! tRNA transcription GO:0009304 17 7 0,000 0,03797048 0,10410985 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03797048 0,10399314 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03797048 0,10387668 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03797048 0,10376049 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03797048 0,10364456 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03797048 0,10352888 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03797048 0,10341346 ! sleep GO:0030431 16 7 0,000 0,03797048 0,1032983 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03797048 0,1031834 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03797048 0,10306875 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03797048 0,10295436 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03797048 0,10284022 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03797048 0,10272633 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03797048 0,1026127 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03797048 0,10249931 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03797048 0,10238618 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03797048 0,10227329 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03797048 0,10216066 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03797048 0,10204827 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03797048 0,10193613 ! glycolipid transport GO:0046836 11 7 0,000 0,03797048 0,10182423 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03797048 0,10171258 GO:0051923|sulfation, ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03797048 0,10160118 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03797048 0,10149002 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03797048 0,1013791 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03797048 0,10126842 ! mRNA stabilization GO:0048255 18 7 0,000 0,03797048 0,10115799 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03797048 0,1010478 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03797048 0,10093784 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03797048 0,10082813 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03797048 0,10071865 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03797048 0,10060941 ! lipoprotein transport GO:0042953 14 7 0,000 0,03797048 0,10050041 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03797048 0,10039164 ! rhythmic behavior GO:0007622 17 7 0,000 0,03797048 0,10028311 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03797048 0,10017481 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03797048 0,10006675 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03797048 0,09995892 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03797048 0,09985132 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03797048 0,09974395 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03797048 0,09963682 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03797048 0,09952991 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03797048 0,09942323 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03797048 0,09931678 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03797048 0,09921056 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03797048 0,09910457 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03797048 0,0989988 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03797048 0,09889326 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03797048 0,09878794 ! spinal cord patterning GO:0021511 14 7 0,000 0,03797048 0,09868285 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03797048 0,09857798 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03797048 0,09847333 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03797048 0,0983689 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03797048 0,0982647 ! adrenal gland development GO:0030325 17 7 0,000 0,03797048 0,09816072 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03797048 0,09805695 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03797048 0,09795341 ! ovulation GO:0030728 10 7 0,000 0,03797048 0,09785008 ! adenohypophysis development GO:0021984 11 7 0,000 0,03797048 0,09774697 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03797048 0,09764408 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03797048 0,09754141 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03797048 0,09743895 ! microtubule nucleation GO:0007020 21 7 0,000 0,03797048 0,0973367 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03797048 0,09723467 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03797048 0,09713286 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03797048 0,09703125 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03797048 0,09692986 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03797048 0,09682868 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03797048 0,09672771 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03797048 0,09662696 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03797048 0,09652641 ! galactose metabolic process GO:0006012 13 7 0,000 0,03797048 0,09642607 ! vesicle fusion GO:0006906 20 7 0,000 0,03797048 0,09632594 ! response to dietary excess GO:0002021 8 7 0,000 0,03797048 0,09622601 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03797048 0,0961263 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03797048 0,09602679 GO:0045851|pH reduction, ! melanosome organization GO:0032438 10 7 0,000 0,03797048 0,09592748 ! nucleoside transport GO:0015858 11 7 0,000 0,03797048 0,09582839 ! nucleoside salvage GO:0043174 11 7 0,000 0,03797048 0,09572949 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03797048 0,0956308 ! male sex determination GO:0030238 15 7 0,000 0,03797048 0,09553231 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03797048 0,09543403 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03797048 0,09533595 ! parturition GO:0007567 16 7 0,000 0,03797048 0,09523807 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03797048 0,09514039 ! rRNA modification GO:0000154 14 7 0,000 0,03797048 0,09504291 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03797048 0,09494563 ! spindle checkpoint GO:0031577 16 7 0,000 0,03797048 0,09484854 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03797048 0,09475166 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03797048 0,09465498 ! monocyte differentiation GO:0030224 16 7 0,000 0,03797048 0,09455849 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03797048 0,0944622 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03797048 0,0943661 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03797048 0,0942702 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03797048 0,09417449 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03797048 0,09407898 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03797048 0,09398366 ! fibrinolysis GO:0042730 11 7 0,000 0,03797048 0,09388854 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03797048 0,09379361 ! eating behavior GO:0042755 8 7 0,000 0,03797048 0,09369887 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03797048 0,09360432 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03797048 0,09350996 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03797048 0,09341579 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03797048 0,09332181 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03797048 0,09322802 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03797048 0,09313441 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03797048 0,093041 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03797048 0,09294777 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03797048 0,09285473 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03797048 0,09276188 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03797048 0,09266921 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03797048 0,09257672 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03797048 0,09248442 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03797048 0,09239231 ! histone ubiquitination GO:0016574 9 7 0,000 0,03797048 0,09230037 ! regulation of meiosis GO:0040020 12 7 0,000 0,03797048 0,09220863 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03797048 0,09211706 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03797048 0,09202567 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03797048 0,09193447 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03797048 0,09184344 ! transcription termination GO:0006353 14 7 0,000 0,03797048 0,0917526 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03797048 0,09166193 ! anaphase GO:0051322 18 7 0,000 0,03797048 0,09157145 GO:0000090|mitotic anaphase, ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03797048 0,09148114 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03797048 0,09139101 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03797048 0,09130106 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03797048 0,09121128 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03797048 0,09112169 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03797048 0,09103226 ! antibiotic transport GO:0042891 9 7 0,000 0,03797048 0,09094302 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03797048 0,09085394 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03797048 0,09076505 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03797048 0,09067632 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03797048 0,09058777 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03797048 0,09049939 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03797048 0,09041119 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03797048 0,09032315 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03797048 0,09023529 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03797048 0,0901476 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03797048 0,09006007 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03797048 0,08997272 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03797048 0,08988554 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03797048 0,08979853 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03797048 0,08971168 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03797048 0,089625 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03797048 0,08953849 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03797048 0,08945215 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03797048 0,08936597 ! muscle adaptation GO:0043500 13 7 0,000 0,03797048 0,08927996 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03797048 0,08919411 ! retina homeostasis GO:0001895 12 7 0,000 0,03797048 0,08910843 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03797048 0,08902291 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03797048 0,08893756 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03797048 0,08885237 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03797048 0,08876735 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03835302 0,08957592 ! muscle fiber development GO:0048747 131 57 1,000 0,03960651 0,09241519 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03960651 0,09232701 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,03960651 0,092239 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,04087542 0,09510347 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,04087542 0,09501298 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,04087542 0,09492266 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04087542 0,09483252 ! nuclear export GO:0051168 110 59 1,000 0,04215952 0,09771889 ! establishment of organelle localization GO:0051656 122 59 1,000 0,04215952 0,09762627 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04327643 0,10011774 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04327643 0,10002302 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04327643 0,09992848 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04327643 0,09983412 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04327643 0,09973993 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04327643 0,09964593 ! male meiosis GO:0007140 9 8 0,000 0,04327643 0,0995521 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04327643 0,09945845 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04327643 0,09936497 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04327643 0,09927167 ! meiotic prophase I GO:0007128 14 8 0,000 0,04327643 0,09917855 ! response to zinc ion GO:0010043 12 8 0,000 0,04327643 0,09908559 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04327643 0,09899282 ! oligopeptide transport GO:0006857 16 8 0,000 0,04327643 0,09890021 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04327643 0,09880778 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04327643 0,09871553 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04327643 0,09862344 ! signal peptide processing GO:0006465 12 8 0,000 0,04327643 0,09853153 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04327643 0,09843979 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04327643 0,09834821 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04327643 0,09825681 ! succinate metabolic process GO:0006105 17 8 0,000 0,04327643 0,09816558 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04327643 0,09807452 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04327643 0,09798362 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04327643 0,0978929 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04327643 0,09780234 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04327643 0,09771195 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04327643 0,09762173 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04327643 0,09753167 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04327643 0,09744178 ! reflex GO:0060004 17 8 0,000 0,04327643 0,09735205 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04327643 0,09726249 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04327643 0,0971731 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04327643 0,09708387 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04327643 0,0969948 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04327643 0,09690589 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04327643 0,09681715 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04327643 0,09672857 ! histidine catabolic process GO:0006548 10 8 0,000 0,04327643 0,09664015 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04327643 0,0965519 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04327643 0,0964638 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04327643 0,09637587 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04327643 0,0962881 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04327643 0,09620048 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04327643 0,09611303 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04327643 0,09602573 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04327643 0,09593859 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04327643 0,09585161 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04327643 0,09576479 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04327643 0,09567813 ! purine salvage GO:0043101 12 8 0,000 0,04327643 0,09559162 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04327643 0,09550527 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04327643 0,09541907 ! osteoblast development GO:0002076 17 8 0,000 0,04327643 0,09533303 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04327643 0,09524714 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04327643 0,09516141 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04327643 0,09507584 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04327643 0,09499041 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04327643 0,09490514 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04327643 0,09482003 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04327643 0,09473506 ! intermediate filament organization GO:0045109 12 8 0,000 0,04327643 0,09465025 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04327643 0,09456559 ! cellular extravasation GO:0045123 13 8 0,000 0,04327643 0,09448108 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04327643 0,09439672 ! response to antibiotic GO:0046677 11 8 0,000 0,04327643 0,09431251 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04327643 0,09422846 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04327643 0,09414455 ! DNA topological change GO:0006265 12 8 0,000 0,04327643 0,09406079 ! response to tropane GO:0014073 15 8 0,000 0,04327643 0,09397718 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04327643 0,09389372 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04327643 0,09381041 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04327643 0,09372724 ! mast cell activation GO:0045576 14 8 0,000 0,04327643 0,09364422 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04327643 0,09356135 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04327643 0,09347863 ! gas homeostasis GO:0033483 14 8 0,000 0,04327643 0,09339605 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04327643 0,09331362 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04327643 0,09323133 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04327643 0,09314919 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04327643 0,09306719 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04327643 0,09298534 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04327643 0,09290363 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04327643 0,09282206 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04327643 0,09274064 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04327643 0,09265936 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04327643 0,09257822 ! response to tumor cell GO:0002347 16 8 0,000 0,04327643 0,09249723 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04327643 0,09241637 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04327643 0,09233566 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04327643 0,09225509 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04327643 0,09217465 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04327643 0,09209436 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04327643 0,09201421 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04327643 0,0919342 ! hormone catabolic process GO:0042447 17 8 0,000 0,04327643 0,09185433 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04327643 0,09177459 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04327643 0,091695 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04327643 0,09161554 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04327643 0,09153622 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04327643 0,09145703 GO:0010828|positive regulation of glucose transport, ! adult feeding behavior GO:0008343 10 8 0,000 0,04327643 0,09137799 ! ATP catabolic process GO:0006200 11 8 0,000 0,04327643 0,09129908 ! blastocyst growth GO:0001832 19 8 0,000 0,04327643 0,0912203 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04327643 0,09114166 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04327643 0,09106316 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04327643 0,09098479 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04327643 0,09090656 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04327643 0,09082846 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04327643 0,0907505 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04327643 0,09067267 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04327643 0,09059497 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04327643 0,09051741 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04327643 0,09043997 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04327643 0,09036267 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04327643 0,09028551 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04327643 0,09020847 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04327643 0,09013157 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04327643 0,09005479 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04327643 0,08997815 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04327643 0,08990164 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04327643 0,08982526 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04327643 0,08974901 ! camera-type eye development GO:0043010 126 61 1,000 0,04477253 0,09277293 ! regulation of mitosis GO:0007088 112 63 1,000 0,04744392 0,09822499 GO:0051783|regulation of nuclear division, ! axon extension GO:0048675 16 9 0,000 0,04855328 0,10043662 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04855328 0,10035165 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04855328 0,10026682 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04855328 0,10018214 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04855328 0,1000976 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04855328 0,1000132 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04855328 0,09992894 ! reproductive behavior GO:0019098 22 9 0,000 0,04855328 0,09984482 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04855328 0,09976085 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04855328 0,09967702 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04855328 0,09959333 ! UTP metabolic process GO:0046051 10 9 0,000 0,04855328 0,09950977 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04855328 0,09942636 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04855328 0,09934309 ! artery development GO:0060840 25 9 0,000 0,04855328 0,09925996 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04855328 0,09917697 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04855328 0,09909411 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04855328 0,0990114 ! equilibrioception GO:0050957 20 9 0,000 0,04855328 0,09892882 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04855328 0,09884638 ! chemosensory behavior GO:0007635 21 9 0,000 0,04855328 0,09876407 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04855328 0,09868191 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04855328 0,09859988 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04855328 0,09851798 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04855328 0,09843623 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04855328 0,0983546 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04855328 0,09827312 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04855328 0,09819176 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04855328 0,09811055 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04855328 0,09802946 ! protein targeting to ER GO:0045047 25 9 0,000 0,04855328 0,09794851 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04855328 0,0978677 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04855328 0,09778702 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,04855328 0,09770647 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04855328 0,09762605 ! glycine catabolic process GO:0006546 15 9 0,000 0,04855328 0,09754577 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04855328 0,09746561 ! endosome organization GO:0007032 20 9 0,000 0,04855328 0,09738559 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04855328 0,0973057 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04855328 0,09722594 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04855328 0,09714632 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04855328 0,09706682 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04855328 0,09698745 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04855328 0,09690821 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04855328 0,0968291 ! receptor clustering GO:0043113 20 9 0,000 0,04855328 0,09675012 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04855328 0,09667127 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04855328 0,09659255 ! retinol metabolic process GO:0042572 20 9 0,000 0,04855328 0,09651396 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04855328 0,09643549 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04855328 0,09635715 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04855328 0,09627894 ! macrophage differentiation GO:0030225 15 9 0,000 0,04855328 0,09620085 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04855328 0,09612289 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04855328 0,09604506 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04855328 0,09596736 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04855328 0,09588977 ! response to amine stimulus GO:0014075 13 9 0,000 0,04855328 0,09581232 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04855328 0,09573499 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04855328 0,09565778 ! erythrocyte development GO:0048821 17 9 0,000 0,04855328 0,0955807 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04855328 0,09550375 ! postreplication repair GO:0006301 25 9 0,000 0,04855328 0,09542691 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04855328 0,0953502 ! icosanoid secretion GO:0032309 15 9 0,000 0,04855328 0,09527362 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04855328 0,09519715 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04855328 0,09512081 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04855328 0,09504459 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04855328 0,0949685 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04855328 0,09489252 ! sterol catabolic process GO:0016127 14 9 0,000 0,04855328 0,09481667 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04855328 0,09474094 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04855328 0,09466532 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04855328 0,09458983 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04855328 0,09451446 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04855328 0,09443921 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04855328 0,09436408 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04855328 0,09428907 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04855328 0,09421418 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04855328 0,09413941 ! purine base metabolic process GO:0006144 25 9 0,000 0,04855328 0,09406475 ! pigment granule transport GO:0051904 17 9 0,000 0,04855328 0,09399022 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04855328 0,0939158 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04855328 0,0938415 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04855328 0,09376731 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04855328 0,09369325 ! mitochondrion localization GO:0051646 18 9 0,000 0,04855328 0,0936193 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,04880101 0,09402276 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,0501721 0,09658821 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,0501721 0,09651216 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 1,000 0,0501721 0,09643623 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,051557 0,09902025 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,05295552 0,10162635 GO:0035113|embryonic appendage morphogenesis, ! secondary metabolic process GO:0019748 125 67 1,000 0,05295552 0,10154658 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,05295552 0,10146694 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05380116 0,10300645 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05380116 0,10292579 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05380116 0,10284525 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05380116 0,10276484 ! associative learning GO:0008306 21 10 0,000 0,05380116 0,10268456 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,05380116 0,1026044 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05380116 0,10252436 ! phosphate transport GO:0006817 24 10 0,000 0,05380116 0,10244445 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05380116 0,10236467 ! CTP metabolic process GO:0046036 11 10 0,000 0,05380116 0,10228501 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,05380116 0,10220547 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05380116 0,10212605 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05380116 0,10204676 ! social behavior GO:0035176 29 10 0,000 0,05380116 0,1019676 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05380116 0,10188855 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05380116 0,10180963 ! androgen metabolic process GO:0008209 17 10 0,000 0,05380116 0,10173083 ! phospholipid efflux GO:0033700 19 10 0,000 0,05380116 0,10165215 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05380116 0,1015736 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05380116 0,10149516 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05380116 0,10141685 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05380116 0,10133865 ! lung alveolus development GO:0048286 26 10 0,000 0,05380116 0,10126058 ! pathogenesis GO:0009405 17 10 0,000 0,05380116 0,10118263 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05380116 0,10110479 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05380116 0,10102708 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05380116 0,10094949 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05380116 0,10087201 ! endoderm development GO:0007492 18 10 0,000 0,05380116 0,10079466 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05380116 0,10071742 ! arginine catabolic process GO:0006527 17 10 0,000 0,05380116 0,1006403 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05380116 0,1005633 ! proline metabolic process GO:0006560 13 10 0,000 0,05380116 0,10048642 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05380116 0,10040965 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05380116 0,100333 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05380116 0,10025647 ! V(D)J recombination GO:0033151 34 10 0,000 0,05380116 0,10018006 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05380116 0,10010376 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05380116 0,10002757 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05380116 0,09995151 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05380116 0,09987556 ! multicellular organism growth GO:0035264 19 10 0,000 0,05380116 0,09979972 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05380116 0,099724 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05380116 0,09964839 ! ruffle organization GO:0031529 17 10 0,000 0,05380116 0,0995729 ! epithelial cell development GO:0002064 21 10 0,000 0,05380116 0,09949753 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05380116 0,09942226 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05380116 0,09934711 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05380116 0,09927208 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05380116 0,09919716 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05380116 0,09912235 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05380116 0,09904765 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,05380116 0,09897307 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05380116 0,09889859 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05380116 0,09882423 ! protein heterooligomerization GO:0051291 17 10 0,000 0,05380116 0,09874999 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05380116 0,09867585 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05380116 0,09860182 ! segment specification GO:0007379 15 10 0,000 0,05380116 0,09852791 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05380116 0,09845411 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05380116 0,09838041 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05380116 0,09830683 ! response to dsRNA GO:0043331 23 10 0,000 0,05380116 0,09823336 ! DNA ligation GO:0006266 18 10 0,000 0,05380116 0,09815999 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05380116 0,09808674 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05380116 0,0980136 ! melanosome localization GO:0032400 16 10 0,000 0,05380116 0,09794056 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05380116 0,09786763 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05380116 0,09779482 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05380116 0,09772211 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05380116 0,0976495 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05380116 0,09757701 ! induction of an organ GO:0001759 17 10 0,000 0,05380116 0,09750462 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05380116 0,09743234 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05380116 0,09736017 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05380116 0,09728811 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05380116 0,09721615 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05380116 0,0971443 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05380116 0,09707255 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05380116 0,09700091 ! salivary gland development GO:0007431 28 10 0,000 0,05380116 0,09692937 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05380116 0,09685795 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05380116 0,09678662 ! midbrain development GO:0030901 14 10 0,000 0,05380116 0,0967154 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05380116 0,09664429 GO:0050879|multicellular organismal movement, ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05380116 0,09657328 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05380116 0,09650237 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05380116 0,09643157 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05380116 0,09636087 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05380116 0,09629028 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05380116 0,09621979 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05380116 0,0961494 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05380116 0,09607912 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05380116 0,09600894 ! blastocyst formation GO:0001825 18 10 0,000 0,05380116 0,09593886 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05380116 0,09586888 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05380116 0,095799 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05380116 0,09572923 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05380116 0,09565956 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05380116 0,09558999 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,05436747 0,09652597 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05436747 0,09645587 ! extracellular matrix organization GO:0030198 146 68 1,000 0,05436747 0,09638587 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,05436747 0,09631597 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,05436747 0,09624618 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05436747 0,09617649 ! adaptive immune response GO:0002250 126 68 1,000 0,05436747 0,09610689 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,05436747 0,0960374 ! lung development GO:0030324 165 69 1,000 0,05579265 0,09848371 ! activation of immune response GO:0002253 120 70 1,000 0,05723089 0,1009495 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,05868198 0,10343441 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05902024 0,10395563 ! respiratory burst GO:0045730 17 11 0,000 0,05902024 0,10388073 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05902024 0,10380594 ! neuron fate specification GO:0048665 18 11 0,000 0,05902024 0,10373126 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05902024 0,10365669 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05902024 0,10358223 ! thyroid gland development GO:0030878 26 11 0,000 0,05902024 0,10350787 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,05902024 0,10343361 ! synapsis GO:0007129 14 11 0,000 0,05902024 0,10335947 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05902024 0,10328543 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05902024 0,10321149 ! response to pain GO:0048265 27 11 0,000 0,05902024 0,10313767 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05902024 0,10306394 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05902024 0,10299033 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05902024 0,10291681 ! bone resorption GO:0045453 16 11 0,000 0,05902024 0,10284341 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05902024 0,10277011 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,05902024 0,10269691 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05902024 0,10262381 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05902024 0,10255082 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05902024 0,10247794 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05902024 0,10240515 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05902024 0,10233248 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05902024 0,1022599 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05902024 0,10218743 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05902024 0,10211505 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05902024 0,10204279 ! UV protection GO:0009650 20 11 0,000 0,05902024 0,10197062 ! adult heart development GO:0007512 16 11 0,000 0,05902024 0,10189856 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05902024 0,10182659 ! macroautophagy GO:0016236 19 11 0,000 0,05902024 0,10175473 ! temperature homeostasis GO:0001659 18 11 0,000 0,05902024 0,10168297 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05902024 0,10161132 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05902024 0,10153976 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05902024 0,1014683 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05902024 0,10139695 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05902024 0,10132569 ! regulation of organ growth GO:0046620 14 11 0,000 0,05902024 0,10125453 ! pigment granule localization GO:0051875 20 11 0,000 0,05902024 0,10118348 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05902024 0,10111252 ! vasoconstriction GO:0042310 20 11 0,000 0,05902024 0,10104167 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05902024 0,10097091 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05902024 0,10090025 ! embryonic axis specification GO:0000578 19 11 0,000 0,05902024 0,10082969 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05902024 0,10075923 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05902024 0,10068887 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05902024 0,1006186 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05902024 0,10054844 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05902024 0,10047837 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05902024 0,1004084 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05902024 0,10033852 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05902024 0,10026875 ! prophase GO:0051324 17 11 0,000 0,05902024 0,10019907 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05902024 0,10012948 ! nucleosome positioning GO:0016584 15 11 0,000 0,05902024 0,10006 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05902024 0,09999061 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05902024 0,09992131 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05902024 0,09985212 ! apical protein localization GO:0045176 18 11 0,000 0,05902024 0,09978302 ! acid secretion GO:0046717 20 11 0,000 0,05902024 0,09971401 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05902024 0,0996451 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05902024 0,09957628 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05902024 0,09950756 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05902024 0,09943894 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05902024 0,0993704 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05902024 0,09930197 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,05902024 0,09923363 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05902024 0,09916538 ! germ cell migration GO:0008354 26 11 0,000 0,05902024 0,09909722 ! embryonic gut development GO:0048566 19 11 0,000 0,05902024 0,09902916 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05902024 0,09896119 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05902024 0,09889332 ! activation of innate immune response GO:0002218 16 11 0,000 0,05902024 0,09882554 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05902024 0,09875785 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05902024 0,09869025 ! lysogeny GO:0030069 22 11 0,000 0,05902024 0,09862275 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05902024 0,09855534 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05902024 0,09848802 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05902024 0,09842079 ! regulation of embryonic development GO:0045995 35 11 0,000 0,05902024 0,09835365 ! nucleus localization GO:0051647 22 11 0,000 0,05902024 0,09828661 ! appendage morphogenesis GO:0035107 150 72 1,000 0,06014576 0,10009271 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,06014576 0,10002457 ! respiratory tube development GO:0030323 171 72 1,000 0,06014576 0,09995653 ! B cell activation GO:0042113 179 72 1,000 0,06014576 0,09988858 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,06014576 0,09982072 ! appendage development GO:0048736 151 73 1,000 0,06162204 0,10220139 GO:0060173|limb development, ! acute inflammatory response GO:0002526 118 74 1,000 0,06311063 0,10459924 ! respiratory system development GO:0060541 175 74 1,000 0,06311063 0,10452832 ! organelle localization GO:0051640 155 74 1,000 0,06311063 0,1044575 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06421069 0,1062063 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06421069 0,10613445 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,06421069 0,10606268 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06421069 0,10599102 ! virus-host interaction GO:0019048 30 12 0,000 0,06421069 0,10591945 ! mating GO:0007618 17 12 0,000 0,06421069 0,10584798 ! protein complex disassembly GO:0043241 28 12 0,000 0,06421069 0,10577661 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06421069 0,10570533 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06421069 0,10563415 ! hippocampus development GO:0021766 29 12 0,000 0,06421069 0,10556306 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,06421069 0,10549207 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06421069 0,10542118 ! T cell proliferation GO:0042098 32 12 0,000 0,06421069 0,10535038 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06421069 0,10527967 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06421069 0,10520906 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06421069 0,10513855 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06421069 0,10506813 ! drug transport GO:0015893 16 12 0,000 0,06421069 0,1049978 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06421069 0,10492757 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06421069 0,10485743 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06421069 0,10478738 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06421069 0,10471743 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06421069 0,10464757 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06421069 0,10457781 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06421069 0,10450814 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06421069 0,10443856 ! lipid digestion GO:0044241 21 12 0,000 0,06421069 0,10436907 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06421069 0,10429967 ! entry into host cell GO:0030260 34 12 0,000 0,06421069 0,10423037 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06421069 0,10416116 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06421069 0,10409204 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06421069 0,10402302 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06421069 0,10395408 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06421069 0,10388524 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06421069 0,10381649 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06421069 0,10374782 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06421069 0,10367925 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06421069 0,10361077 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06421069 0,10354238 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06421069 0,10347408 ! cranial nerve development GO:0021545 23 12 0,000 0,06421069 0,10340587 ! fucose catabolic process GO:0019317 25 12 0,000 0,06421069 0,10333775 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06421069 0,10326972 ! histone acetylation GO:0016573 27 12 0,000 0,06421069 0,10320178 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06421069 0,10313393 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06421069 0,10306617 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06421069 0,1029985 ! zymogen activation GO:0031638 18 12 0,000 0,06421069 0,10293091 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06421069 0,10286342 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06421069 0,10279601 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06421069 0,10272869 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06421069 0,10266146 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06421069 0,10259432 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06421069 0,10252726 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06421069 0,10246029 ! defense response to fungus GO:0050832 15 12 0,000 0,06421069 0,10239341 ! developmental induction GO:0031128 22 12 0,000 0,06421069 0,10232662 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06421069 0,10225992 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06421069 0,1021933 ! response to cold GO:0009409 17 12 0,000 0,06421069 0,10212676 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06421069 0,10206032 ! localization within membrane GO:0051668 26 12 0,000 0,06421069 0,10199396 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,06461137 0,10256372 GO:0090046|regulation of transcription regulator activity, ! rhythmic process GO:0048511 142 75 1,000 0,06461137 0,10249712 ! learning or memory GO:0007611 161 76 1,000 0,06612406 0,10482873 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,06612406 0,10476075 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06937265 0,10983628 ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06937265 0,10976514 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06937265 0,10969409 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06937265 0,10962314 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06937265 0,10955228 ! peroxisomal transport GO:0043574 28 13 0,000 0,06937265 0,10948151 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06937265 0,10941083 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06937265 0,10934024 ! organelle fusion GO:0048284 36 13 0,000 0,06937265 0,10926975 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06937265 0,10919934 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06937265 0,10912902 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06937265 0,1090588 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06937265 0,10898867 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06937265 0,10891862 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06937265 0,10884867 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06937265 0,1087788 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06937265 0,10870903 ! methionine metabolic process GO:0006555 31 13 0,000 0,06937265 0,10863934 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06937265 0,10856975 ! Golgi organization GO:0007030 25 13 0,000 0,06937265 0,10850024 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06937265 0,10843082 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06937265 0,10836149 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06937265 0,10829225 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06937265 0,1082231 ! exocrine system development GO:0035272 34 13 0,000 0,06937265 0,10815404 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06937265 0,10808506 ! monoamine transport GO:0015844 21 13 0,000 0,06937265 0,10801617 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06937265 0,10794737 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06937265 0,10787866 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06937265 0,10781004 ! protein homotetramerization GO:0051289 24 13 0,000 0,06937265 0,1077415 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06937265 0,10767305 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06937265 0,10760468 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06937265 0,10753641 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06937265 0,10746822 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06937265 0,10740011 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06937265 0,10733209 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,06937265 0,10726416 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06937265 0,10719632 ! histone methylation GO:0016571 29 13 0,000 0,06937265 0,10712856 ! chromatin silencing GO:0006342 29 13 0,000 0,06937265 0,10706088 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06937265 0,10699329 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06937265 0,10692579 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06937265 0,10685837 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06937265 0,10679104 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06937265 0,10672379 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06937265 0,10665662 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06937265 0,10658954 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06937265 0,10652255 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06937265 0,10645564 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06937265 0,10638881 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06937265 0,10632207 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06937265 0,10625541 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06937265 0,10618883 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06937265 0,10612234 ! insulin secretion GO:0030073 24 13 0,000 0,06937265 0,10605593 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06937265 0,1059896 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06937265 0,10592336 ! acrosome reaction GO:0007340 19 13 0,000 0,06937265 0,1058572 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06937265 0,10579112 ! blood coagulation GO:0007596 151 79 1,000 0,07073215 0,10779704 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,07073215 0,10772983 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,07229095 0,11003538 ! response to hypoxia GO:0001666 178 81 1,000 0,07386084 0,11235493 ! rRNA transcription GO:0009303 28 14 0,000 0,07450628 0,11326623 ! regulation of S phase GO:0033261 26 14 0,000 0,07450628 0,11319579 ! water transport GO:0006833 21 14 0,000 0,07450628 0,11312544 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07450628 0,11305517 ! non-recombinational repair GO:0000726 29 14 0,000 0,07450628 0,112985 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07450628 0,11291491 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07450628 0,1128449 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07450628 0,11277499 ! lipid localization GO:0010876 32 14 0,000 0,07450628 0,11270516 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07450628 0,11263541 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07450628 0,11256576 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07450628 0,11249619 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07450628 0,1124267 ! arginine metabolic process GO:0006525 21 14 0,000 0,07450628 0,1123573 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07450628 0,11228799 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07450628 0,11221876 ! regulation of heart rate GO:0002027 25 14 0,000 0,07450628 0,11214962 ! organic alcohol transport GO:0015850 29 14 0,000 0,07450628 0,11208056 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07450628 0,11201159 ! embryo implantation GO:0007566 30 14 0,000 0,07450628 0,1119427 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07450628 0,1118739 ! bone mineralization GO:0030282 18 14 0,000 0,07450628 0,11180518 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07450628 0,11173654 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07450628 0,11166799 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07450628 0,11159953 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07450628 0,11153115 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07450628 0,11146285 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07450628 0,11139463 ! ribosome assembly GO:0042255 18 14 0,000 0,07450628 0,1113265 ! cerebellum development GO:0021549 23 14 0,000 0,07450628 0,11125845 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07450628 0,11119049 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07450628 0,11112261 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07450628 0,11105481 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07450628 0,11098709 ! NADP metabolic process GO:0006739 24 14 0,000 0,07450628 0,11091946 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07450628 0,11085191 ! oxygen transport GO:0015671 22 14 0,000 0,07450628 0,11078444 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07450628 0,11071705 ! male genitalia development GO:0030539 26 14 0,000 0,07450628 0,11064974 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07450628 0,11058252 ! regulation of axon extension GO:0030516 43 14 0,000 0,07450628 0,11051538 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07450628 0,11044832 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07450628 0,11038134 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,07703323 0,11405587 ! response to drug GO:0042493 149 83 1,000 0,07703323 0,11398679 ! response to oxygen levels GO:0070482 183 83 1,000 0,07703323 0,11391779 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,07703323 0,11384887 ! T cell activation GO:0042110 189 84 1,000 0,07863541 0,11614649 ! lactation GO:0007595 30 15 0,000 0,07961173 0,11751749 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,07961173 0,11744653 ! reproductive cellular process GO:0048610 22 15 0,000 0,07961173 0,11737565 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07961173 0,11730486 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07961173 0,11723415 ! superoxide anion generation GO:0042554 22 15 0,000 0,07961173 0,11716353 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07961173 0,11709299 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07961173 0,11702254 ! copper ion transport GO:0006825 22 15 0,000 0,07961173 0,11695217 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07961173 0,11688188 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07961173 0,11681168 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07961173 0,11674157 ! sulfate transport GO:0008272 27 15 0,000 0,07961173 0,11667154 ! response to cAMP GO:0051591 25 15 0,000 0,07961173 0,11660159 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07961173 0,11653173 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07961173 0,11646195 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07961173 0,11639225 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07961173 0,11632264 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! vesicle coating GO:0006901 38 15 0,000 0,07961173 0,11625311 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07961173 0,11618366 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07961173 0,1161143 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07961173 0,11604502 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07961173 0,11597582 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07961173 0,11590671 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07961173 0,11583767 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07961173 0,11576872 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07961173 0,11569985 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07961173 0,11563107 ! histone deacetylation GO:0016575 24 15 0,000 0,07961173 0,11556236 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07961173 0,11549374 ! cofactor transport GO:0051181 30 15 0,000 0,07961173 0,1154252 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07961173 0,11535673 ! muscle maintenance GO:0046716 26 15 0,000 0,07961173 0,11528835 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07961173 0,11522006 ! intestinal absorption GO:0050892 31 15 0,000 0,07961173 0,11515184 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07961173 0,1150837 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07961173 0,11501564 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07961173 0,11494767 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07961173 0,11487977 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07961173 0,11481196 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07961173 0,11474422 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07961173 0,11467656 ! actin filament polymerization GO:0030041 27 15 0,000 0,07961173 0,11460899 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07961173 0,11454149 ! hemostasis GO:0007599 165 85 1,000 0,08024802 0,115389 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,08024802 0,11532112 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,08024802 0,11525332 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,08187089 0,11751504 ! regulation of lyase activity GO:0051339 169 86 1,000 0,08187089 0,11744603 ! regulation of protein transport GO:0051223 165 87 1,000 0,08350388 0,1197183 GO:0070201|regulation of establishment of protein localization, ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08468916 0,12134641 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08468916 0,12127528 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08468916 0,12120423 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08468916 0,12113327 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08468916 0,12106239 ! bone remodeling GO:0046849 28 16 0,000 0,08468916 0,12099159 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08468916 0,12092088 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08468916 0,12085025 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08468916 0,1207797 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08468916 0,12070923 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08468916 0,12063885 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08468916 0,12056854 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08468916 0,12049832 ! startle response GO:0001964 28 16 0,000 0,08468916 0,12042818 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08468916 0,12035813 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08468916 0,12028815 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08468916 0,12021826 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08468916 0,12014844 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08468916 0,12007871 ! pituitary gland development GO:0021983 30 16 0,000 0,08468916 0,12000906 ! response to osmotic stress GO:0006970 27 16 0,000 0,08468916 0,11993949 ! lysosomal transport GO:0007041 31 16 0,000 0,08468916 0,11987 ! fructose metabolic process GO:0006000 25 16 0,000 0,08468916 0,11980059 ! L-amino acid transport GO:0015807 33 16 0,000 0,08468916 0,11973126 ! stem cell development GO:0048864 46 16 0,000 0,08468916 0,11966201 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08468916 0,11959284 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08468916 0,11952376 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08468916 0,11945475 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08468916 0,11938582 ! axon cargo transport GO:0008088 46 16 0,000 0,08468916 0,11931697 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08468916 0,1192482 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08468916 0,11917951 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,08468916 0,11911089 ! DNA replication initiation GO:0006270 28 16 0,000 0,08468916 0,11904236 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08468916 0,11897391 ! tissue regeneration GO:0042246 27 16 0,000 0,08468916 0,11890553 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08468916 0,11883723 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08468916 0,11876901 ! biomineral formation GO:0031214 22 16 0,000 0,08468916 0,11870087 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08468916 0,11863281 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08468916 0,11856483 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08468916 0,11849692 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08468916 0,11842909 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08468916 0,11836134 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08468916 0,11829367 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08468916 0,11822607 ! peptide hormone processing GO:0016486 27 16 0,000 0,08468916 0,11815855 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,08514682 0,11872926 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,08679954 0,12096479 ! regulation of DNA binding GO:0051101 167 89 1,000 0,08679954 0,12089583 ! response to unfolded protein GO:0006986 139 90 1,000 0,08846191 0,12314099 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08973873 0,12484721 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08973873 0,12477616 ! signal complex assembly GO:0007172 47 17 0,000 0,08973873 0,12470518 ! filopodium assembly GO:0046847 42 17 0,000 0,08973873 0,12463428 ! endothelial cell migration GO:0043542 31 17 0,000 0,08973873 0,12456347 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08973873 0,12449274 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08973873 0,12442208 ! glial cell development GO:0021782 28 17 0,000 0,08973873 0,12435151 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08973873 0,12428101 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08973873 0,1242106 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08973873 0,12414026 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08973873 0,12407001 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08973873 0,12399983 ! myoblast differentiation GO:0045445 50 17 0,000 0,08973873 0,12392974 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08973873 0,12385972 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,08973873 0,12378978 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08973873 0,12371993 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08973873 0,12365015 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08973873 0,12358044 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08973873 0,12351082 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08973873 0,12344128 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08973873 0,12337181 ! membrane budding GO:0006900 42 17 0,000 0,08973873 0,12330242 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08973873 0,12323311 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08973873 0,12316388 ! genitalia development GO:0048806 32 17 0,000 0,08973873 0,12309473 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08973873 0,12302565 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08973873 0,12295665 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08973873 0,12288773 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08973873 0,12281888 ! steroid catabolic process GO:0006706 34 17 0,000 0,08973873 0,12275012 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08973873 0,12268143 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08973873 0,12261281 ! gas transport GO:0015669 26 17 0,000 0,08973873 0,12254427 ! organic cation transport GO:0015695 32 17 0,000 0,08973873 0,12247581 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08973873 0,12240743 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08973873 0,12233912 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,09013375 0,12280912 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,09350526 0,12733185 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,09350526 0,12726092 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09476057 0,1288976 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09476057 0,12882587 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09476057 0,12875422 ! limbic system development GO:0021761 40 18 0,000 0,09476057 0,12868265 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09476057 0,12861116 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09476057 0,12853975 ! adult walking behavior GO:0007628 36 18 0,000 0,09476057 0,12846841 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09476057 0,12839716 ! heart looping GO:0001947 34 18 0,000 0,09476057 0,12832599 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09476057 0,12825489 ! centrosome cycle GO:0007098 26 18 0,000 0,09476057 0,12818388 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09476057 0,12811294 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09476057 0,12804208 ! glycine metabolic process GO:0006544 30 18 0,000 0,09476057 0,1279713 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09476057 0,1279006 ! response to retinoic acid GO:0032526 31 18 0,000 0,09476057 0,12782997 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,09476057 0,12775943 ! DNA integration GO:0015074 32 18 0,000 0,09476057 0,12768896 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,09476057 0,12761857 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09476057 0,12754826 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09476057 0,12747802 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09476057 0,12740786 ! neural crest cell migration GO:0001755 41 18 0,000 0,09476057 0,12733778 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09476057 0,12726778 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09476057 0,12719785 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09476057 0,127128 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09476057 0,12705822 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,09476057 0,12698853 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09476057 0,12691891 ! detection of bacterium GO:0016045 22 18 0,000 0,09476057 0,12684936 ! nerve development GO:0021675 34 18 0,000 0,09476057 0,12677989 ! microspike assembly GO:0030035 46 18 0,000 0,09476057 0,1267105 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09476057 0,12664118 ! female pregnancy GO:0007565 166 94 1,000 0,09520462 0,12716506 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,09520462 0,12709557 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,09691286 0,12930536 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,09691286 0,12923478 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09975486 0,13295206 ! positive regulation of translation GO:0045727 31 19 0,000 0,09975486 0,13287956 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09975486 0,13280715 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09975486 0,13273481 ! neuron maturation GO:0042551 46 19 0,000 0,09975486 0,13266256 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09975486 0,13259038 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09975486 0,13251828 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09975486 0,13244626 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09975486 0,13237432 ! inositol metabolic process GO:0006020 33 19 0,000 0,09975486 0,13230245 ! memory GO:0007613 34 19 0,000 0,09975486 0,13223067 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09975486 0,13215896 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09975486 0,13208733 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09975486 0,13201577 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09975486 0,1319443 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09975486 0,1318729 ! cerebral cortex development GO:0021987 40 19 0,000 0,09975486 0,13180158 ! pigmentation during development GO:0048066 42 19 0,000 0,09975486 0,13173033 ! response to vitamin A GO:0033189 32 19 0,000 0,09975486 0,13165917 ! heme metabolic process GO:0042168 40 19 0,000 0,09975486 0,13158808 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09975486 0,13151706 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09975486 0,13144613 ! response to fungus GO:0009620 26 19 0,000 0,09975486 0,13137527 ! peptide cross-linking GO:0018149 39 19 0,000 0,09975486 0,13130448 ! protein export from nucleus GO:0006611 40 19 0,000 0,09975486 0,13123377 ! heart process GO:0003015 32 19 0,000 0,09975486 0,13116314 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09975486 0,13109259 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09975486 0,13102211 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09975486 0,1309517 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09975486 0,13088137 ! vitamin transport GO:0051180 31 19 0,000 0,09975486 0,13081112 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09975486 0,13074094 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09975486 0,13067084 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09975486 0,13060081 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09975486 0,13053086 ! cilium assembly GO:0042384 38 19 0,000 0,09975486 0,13046098 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09975486 0,13039118 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,10035536 0,13110596 ! transcription initiation GO:0006352 171 97 1,000 0,10035536 0,13103589 ! leukocyte differentiation GO:0002521 232 98 1,000 0,10208933 0,13322876 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,10208933 0,13315763 ! protein secretion GO:0009306 45 20 0,000 0,10472173 0,13651824 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10472173 0,13644543 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10472173 0,1363727 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10472173 0,13630004 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,10472173 0,13622747 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10472173 0,13615497 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10472173 0,13608254 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,10472173 0,1360102 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10472173 0,13593793 ! response to vitamin GO:0033273 36 20 0,000 0,10472173 0,13586574 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10472173 0,13579362 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,10472173 0,13572158 GO:0010675|regulation of cellular carbohydrate metabolic process, ! bile acid metabolic process GO:0008206 34 20 0,000 0,10472173 0,13564962 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10472173 0,13557773 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10472173 0,13550592 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10472173 0,13543419 GO:0032392|DNA geometric change, ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10472173 0,13536253 ! peptide secretion GO:0002790 38 20 0,000 0,10472173 0,13529095 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10472173 0,13521944 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,10472173 0,13514801 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10472173 0,13507665 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10472173 0,13500537 GO:0006626|protein targeting to mitochondrion, ! cell-cell junction organization GO:0045216 43 20 0,000 0,10472173 0,13493417 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10472173 0,13486304 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,10472173 0,13479198 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,10472173 0,134721 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10472173 0,1346501 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10472173 0,13457926 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10472173 0,13450851 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10472173 0,13443783 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,105582 0,13547102 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,105582 0,13539991 ! regulation of cell killing GO:0031341 46 21 0,000 0,10966133 0,14055752 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10966133 0,14048382 ! hormone secretion GO:0046879 39 21 0,000 0,10966133 0,14041019 ! lipid phosphorylation GO:0046834 43 21 0,000 0,10966133 0,14033664 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10966133 0,14026316 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10966133 0,14018976 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10966133 0,14011644 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10966133 0,1400432 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,10966133 0,13997003 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10966133 0,13989694 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10966133 0,13982392 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10966133 0,13975098 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10966133 0,13967812 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10966133 0,13960533 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10966133 0,13953262 ! sensory perception of pain GO:0019233 33 21 0,000 0,10966133 0,13945999 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10966133 0,13938743 ! diencephalon development GO:0021536 36 21 0,000 0,10966133 0,13931494 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,10966133 0,13924253 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10966133 0,1391702 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10966133 0,13909794 ! collagen catabolic process GO:0030574 29 21 0,000 0,10966133 0,13902576 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10966133 0,13895365 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10966133 0,13888162 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10966133 0,13880966 ! actin filament-based movement GO:0030048 47 21 0,000 0,10966133 0,13873777 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,10966133 0,13866596 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11457382 0,14480282 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11457382 0,14472795 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11457382 0,14465315 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11457382 0,14457843 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11457382 0,14450379 ! microtubule-based transport GO:0010970 59 22 0,000 0,11457382 0,14442923 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11457382 0,14435474 ! cellular response to starvation GO:0009267 37 22 0,000 0,11457382 0,14428034 ! vacuolar transport GO:0007034 41 22 0,000 0,11457382 0,144206 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11457382 0,14413175 ! fucose metabolic process GO:0006004 44 22 0,000 0,11457382 0,14405757 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11457382 0,14398346 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11457382 0,14390943 ! stem cell differentiation GO:0048863 57 22 0,000 0,11457382 0,14383548 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11457382 0,14376161 ! cytolysis GO:0019835 27 22 0,000 0,11457382 0,14368781 ! vasodilation GO:0042311 40 22 0,000 0,11457382 0,14361408 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11457382 0,14354044 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11457382 0,14346686 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11457382 0,14339337 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11457382 0,14331994 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11457382 0,1432466 ! sarcomere organization GO:0045214 32 22 0,000 0,11457382 0,14317332 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,11457382 0,14310013 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11457382 0,14302701 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11457382 0,14295396 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11457382 0,14288099 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11457382 0,14280809 ! protein stabilization GO:0050821 41 22 0,000 0,11457382 0,14273526 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,11945935 0,14874576 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11945935 0,14866999 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11945935 0,14859429 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11945935 0,14851867 ! gluconeogenesis GO:0006094 38 23 0,000 0,11945935 0,14844312 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11945935 0,14836766 ! viral genome replication GO:0019079 44 23 0,000 0,11945935 0,14829227 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11945935 0,14821695 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11945935 0,14814172 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11945935 0,14806656 ! axis specification GO:0009798 43 23 0,000 0,11945935 0,14799147 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11945935 0,14791646 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11945935 0,14784153 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11945935 0,14776667 ! peroxisome organization GO:0007031 43 23 0,000 0,11945935 0,14769189 ! lysosome organization GO:0007040 47 23 0,000 0,11945935 0,14761719 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11945935 0,14754256 ! vesicle targeting GO:0006903 49 23 0,000 0,11945935 0,147468 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,11945935 0,14739353 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11945935 0,14731912 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11945935 0,14724479 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11945935 0,14717054 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11945935 0,14709636 ! DNA modification GO:0006304 36 23 0,000 0,11945935 0,14702226 ! fatty acid transport GO:0015908 47 23 0,000 0,11945935 0,14694823 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11945935 0,14687427 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11945935 0,14680039 ! hormone transport GO:0009914 41 23 0,000 0,11945935 0,14672659 ! cell-cell recognition GO:0009988 28 23 0,000 0,11945935 0,14665285 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11945935 0,1465792 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11945935 0,14650561 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11945935 0,1464321 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12431805 0,15231143 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12431805 0,15223508 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,12431805 0,15215881 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12431805 0,15208262 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12431805 0,1520065 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12431805 0,15193046 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12431805 0,1518545 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,12431805 0,15177861 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,12431805 0,15170279 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,12431805 0,15162706 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,12431805 0,15155139 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,12431805 0,15147581 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,12431805 0,15140029 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12431805 0,15132486 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,12431805 0,1512495 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12431805 0,15117421 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12431805 0,151099 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12431805 0,15102386 ! membrane depolarization GO:0051899 45 24 0,000 0,12431805 0,1509488 ! pallium development GO:0021543 56 24 0,000 0,12431805 0,15087382 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,12431805 0,1507989 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12431805 0,15072407 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,12431805 0,1506493 ! platelet activation GO:0030168 41 24 0,000 0,12431805 0,15057461 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12431805 0,1505 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12431805 0,15042545 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12431805 0,15035099 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12431805 0,15027659 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,12431805 0,15020227 ! regulation of amine transport GO:0051952 41 24 0,000 0,12431805 0,15012802 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,12431805 0,15005385 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,12915008 0,1558092 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12915008 0,1557323 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12915008 0,15565547 ! leukocyte adhesion GO:0007159 55 25 0,000 0,12915008 0,15557872 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12915008 0,15550204 ! phototransduction GO:0007602 37 25 0,000 0,12915008 0,15542544 ! keratinization GO:0031424 37 25 0,000 0,12915008 0,15534891 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,12915008 0,15527246 ! vacuole organization GO:0007033 49 25 0,000 0,12915008 0,15519608 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12915008 0,15511978 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,12915008 0,15504356 ! receptor metabolic process GO:0043112 53 25 0,000 0,12915008 0,15496741 ! chromosome condensation GO:0030261 48 25 0,000 0,12915008 0,15489133 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12915008 0,15481533 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12915008 0,1547394 ! interaction with host GO:0051701 66 25 0,000 0,12915008 0,15466355 ! immunoglobulin production GO:0002377 62 25 0,000 0,12915008 0,15458777 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12915008 0,15451207 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12915008 0,15443644 ! liver development GO:0001889 55 25 0,000 0,12915008 0,15436088 ! protein tetramerization GO:0051262 57 25 0,000 0,12915008 0,1542854 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13395558 0,15994794 ! initiation of viral infection GO:0019059 60 26 0,000 0,13395558 0,1598698 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13395558 0,15979174 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13395558 0,15971375 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13395558 0,15963584 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,13395558 0,15955801 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,13395558 0,15948025 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13395558 0,15940257 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,13395558 0,15932496 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13395558 0,15924743 ! digestive system process GO:0022600 49 26 0,000 0,13395558 0,15916998 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13395558 0,1590926 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,13395558 0,15901529 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13395558 0,15893807 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13395558 0,15886091 ! neural crest cell development GO:0014032 59 26 0,000 0,13395558 0,15878383 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13395558 0,15870683 ! negative regulation of cell development GO:0010721 83 26 0,000 0,13395558 0,1586299 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13395558 0,15855304 ! pentose metabolic process GO:0019321 43 26 0,000 0,13395558 0,15847626 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13395558 0,15839955 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13395558 0,15832292 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13395558 0,15824636 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13395558 0,15816988 ! blastocyst development GO:0001824 50 26 0,000 0,13395558 0,15809347 ! telomere organization GO:0032200 46 26 0,000 0,13395558 0,15801713 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13395558 0,15794087 ! alditol metabolic process GO:0019400 44 26 0,000 0,13395558 0,15786468 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13395558 0,15778856 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13395558 0,15771252 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1387347 0,16326053 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1387347 0,16318193 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1387347 0,1631034 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1387347 0,16302495 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1387347 0,16294657 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1387347 0,16286827 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1387347 0,16279004 ! iron ion transport GO:0006826 65 27 0,000 0,1387347 0,16271189 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1387347 0,16263381 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1387347 0,16255581 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1387347 0,16247788 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,1387347 0,16240003 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1387347 0,16232225 ! response to starvation GO:0042594 47 27 0,000 0,1387347 0,16224455 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1387347 0,16216692 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,1387347 0,16208936 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1387347 0,16201188 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,14348757 0,16748215 ! neuron fate commitment GO:0048663 52 28 0,000 0,14348757 0,16740217 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,14348757 0,16732226 ! protein amino acid acylation GO:0043543 59 28 0,000 0,14348757 0,16724244 ! vesicle docking GO:0048278 55 28 0,000 0,14348757 0,16716268 ! circadian rhythm GO:0007623 56 28 0,000 0,14348757 0,167083 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,14348757 0,1670034 ! sperm motility GO:0030317 37 28 0,000 0,14348757 0,16692388 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,14348757 0,16684443 ! base-excision repair GO:0006284 41 28 0,000 0,14348757 0,16676505 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,14348757 0,16668576 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,14348757 0,16660653 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,14348757 0,16652738 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,14348757 0,16644831 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,14348757 0,16636931 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,14348757 0,16629039 ! glutathione metabolic process GO:0006749 42 28 0,000 0,14348757 0,16621154 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,14348757 0,16613277 ! lipid oxidation GO:0034440 48 28 0,000 0,14348757 0,16605407 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,14348757 0,16597545 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,14348757 0,1658969 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,14821436 0,17128083 ! translational initiation GO:0006413 66 29 0,000 0,14821436 0,17119985 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14821436 0,17111894 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14821436 0,17103811 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,14821436 0,17095735 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14821436 0,17087668 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14821436 0,17079607 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14821436 0,17071555 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,14821436 0,1706351 ! somitogenesis GO:0001756 52 29 0,000 0,14821436 0,17055472 ! synaptogenesis GO:0007416 46 29 0,000 0,14821436 0,17047442 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,14821436 0,1703942 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14821436 0,17031405 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14821436 0,17023398 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,15291519 0,17555066 ! phenol metabolic process GO:0018958 56 30 0,000 0,15291519 0,1754682 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,15291519 0,17538582 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,15291519 0,17530352 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,15291519 0,1752213 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,15291519 0,17513915 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,15291519 0,17505708 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,15291519 0,17497508 ! acute-phase response GO:0006953 50 30 0,000 0,15291519 0,17489317 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,15291519 0,17481133 ! myofibril assembly GO:0030239 50 30 0,000 0,15291519 0,17472956 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,15291519 0,17464787 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,15291519 0,17456626 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,15291519 0,17448473 ! cell fate determination GO:0001709 64 30 0,000 0,15291519 0,17440327 ! phospholipid transport GO:0015914 65 30 0,000 0,15291519 0,17432189 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,15291519 0,17424058 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,15291519 0,17415935 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,15291519 0,17407819 ! regulation of coagulation GO:0050818 52 30 0,000 0,15291519 0,17399711 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15759021 0,17923318 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15759021 0,17914978 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15759021 0,17906645 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15759021 0,17898321 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15759021 0,17890004 ! peptide transport GO:0015833 60 31 0,000 0,15759021 0,17881694 ! detection of light stimulus GO:0009583 44 31 0,000 0,15759021 0,17873393 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,15759021 0,17865099 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,15759021 0,17856812 ! natural killer cell activation GO:0030101 50 31 0,000 0,15759021 0,17848534 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15759021 0,17840263 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15759021 0,17832 ! eye morphogenesis GO:0048592 65 31 0,000 0,15759021 0,17823744 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15759021 0,17815496 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,16223956 0,1833262 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,16223956 0,18324144 ! collagen metabolic process GO:0032963 49 32 0,000 0,16223956 0,18315676 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,16223956 0,18307216 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,16223956 0,18298764 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,16223956 0,1829032 ! muscle cell development GO:0055001 52 32 0,000 0,16223956 0,18281884 ! mesoderm formation GO:0001707 73 32 0,000 0,16223956 0,18273455 ! BMP signaling pathway GO:0030509 71 32 0,000 0,16223956 0,18265034 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,16223956 0,18256621 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,16223956 0,18248215 ! gene silencing GO:0016458 71 32 0,000 0,16223956 0,18239818 ! regulation of pH GO:0006885 56 33 0,000 0,16686337 0,18751022 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,16686337 0,18742401 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16686337 0,18733788 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16686337 0,18725183 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,16686337 0,18716585 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16686337 0,18707996 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,16686337 0,18699414 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16686337 0,1869084 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16686337 0,18682274 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,16686337 0,18673716 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,16686337 0,18665166 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,16686337 0,18656623 ! glial cell differentiation GO:0010001 67 34 0,000 0,1714618 0,19161994 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,1714618 0,19153232 ! cholesterol transport GO:0030301 62 34 0,000 0,1714618 0,19144478 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,1714618 0,19135732 ! spliceosome assembly GO:0000245 75 34 0,000 0,1714618 0,19126995 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1714618 0,19118265 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,1714618 0,19109543 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1714618 0,19100829 ! cell fate specification GO:0001708 56 34 0,000 0,1714618 0,19092123 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,1714618 0,19083425 ! adult locomotory behavior GO:0008344 62 34 0,000 0,1714618 0,19074735 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,1714618 0,19066053 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,17603498 0,19565671 ! negative regulation of secretion GO:0051048 68 35 0,000 0,17603498 0,19556774 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,17603498 0,19547884 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,17603498 0,19539003 ! membrane docking GO:0022406 69 35 0,000 0,17603498 0,1953013 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,17603498 0,19521264 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,17603498 0,19512407 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,17603498 0,19503558 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,17603498 0,19494717 ! ceramide metabolic process GO:0006672 72 35 0,000 0,17603498 0,19485884 ! telencephalon development GO:0021537 81 35 0,000 0,17603498 0,19477059 ! sterol transport GO:0015918 63 35 0,000 0,17603498 0,19468241 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,17603498 0,19459432 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,17603498 0,19450631 ! placenta development GO:0001890 53 35 0,000 0,17603498 0,19441838 ! vesicle localization GO:0051648 70 35 0,000 0,17603498 0,19433053 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,18058304 0,19926123 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,18058304 0,19917127 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,18058304 0,19908139 ! protein targeting to membrane GO:0006612 75 36 0,000 0,18058304 0,1989916 ! regulation of proteolysis GO:0030162 77 36 0,000 0,18058304 0,19890188 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,18058304 0,19881224 ! aerobic respiration GO:0009060 56 36 0,000 0,18058304 0,19872269 ! cytokine production GO:0001816 68 36 0,000 0,18058304 0,19863321 ! embryonic organ development GO:0048568 67 36 0,000 0,18058304 0,19854382 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,18510613 0,20342522 ! actomyosin structure organization GO:0031032 68 37 0,000 0,18510613 0,20333375 ! tissue remodeling GO:0048771 78 37 0,000 0,18510613 0,20324237 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,18510613 0,20315106 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,18510613 0,20305984 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,18510613 0,2029687 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,18960437 0,20780775 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,18960437 0,20771457 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,18960437 0,20762146 ! organic anion transport GO:0015711 82 38 0,000 0,18960437 0,20752844 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18960437 0,2074355 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,18960437 0,20734265 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18960437 0,20724988 ! spermatid development GO:0007286 69 38 0,000 0,18960437 0,20715719 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,19407791 0,21195009 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,19407791 0,21185538 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,19407791 0,21176076 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,19407791 0,21166622 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,19407791 0,21157177 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,19407791 0,2114774 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,19407791 0,21138312 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,19407791 0,21128892 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,19407791 0,21119481 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,19852688 0,21593997 ! lipid homeostasis GO:0055088 75 40 0,000 0,19852688 0,21584387 ! mismatch repair GO:0006298 58 40 0,000 0,19852688 0,21574785 ! RNA export from nucleus GO:0006405 61 41 0,000 0,20295142 0,22045812 ! mRNA catabolic process GO:0006402 79 41 0,000 0,20295142 0,22036014 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,20295142 0,22026225 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,20295142 0,22016444 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,20295142 0,22006672 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,20295142 0,21996909 ! gliogenesis GO:0042063 91 41 0,000 0,20295142 0,21987154 ! feeding behavior GO:0007631 69 41 0,000 0,20295142 0,21977408 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,20295142 0,2196767 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,20295142 0,21957942 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,20295142 0,21948221 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,20295142 0,2193851 ! spermatid differentiation GO:0048515 73 41 0,000 0,20295142 0,21928807 ! RNA modification GO:0009451 64 41 0,000 0,20295142 0,21919112 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,20735165 0,22384449 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,20735165 0,22374562 ! regulation of protein secretion GO:0050708 77 42 0,000 0,20735165 0,22364684 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,20735165 0,22354814 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,20735165 0,22344953 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,21172772 0,22806474 GO:0090047|positive regulation of transcription regulator activity, ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,21172772 0,22796422 ! regulation of tube size GO:0035150 76 43 0,000 0,21172772 0,2278638 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,21172772 0,22776346 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,21172772 0,22766321 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,21172772 0,22756305 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,21172772 0,22746298 ! segmentation GO:0035282 78 43 0,000 0,21172772 0,227363 ! ion transmembrane transport GO:0034220 79 43 0,000 0,21172772 0,2272631 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,21607975 0,2318326 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,21607975 0,23173083 ! striated muscle contraction GO:0006941 85 44 0,000 0,21607975 0,23162915 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,21607975 0,23152756 ! double-strand break repair GO:0006302 85 44 0,000 0,21607975 0,23142605 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,22040787 0,23595812 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,22040787 0,23585477 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,22040787 0,2357515 ! biopolymer methylation GO:0043414 91 45 0,000 0,22040787 0,23564833 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,22040787 0,23554525 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,22040787 0,23544225 ! polyol metabolic process GO:0019751 77 45 0,000 0,22040787 0,23533935 ! maintenance of location in cell GO:0051651 101 45 0,000 0,22040787 0,23523654 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,22471222 0,23972574 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,22471222 0,23962111 ! glycolysis GO:0006096 71 46 0,000 0,22471222 0,23951656 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,22471222 0,2394121 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,22471222 0,23930774 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,22471222 0,23920347 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,23325011 0,24818381 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,23325011 0,24807576 ! endosome transport GO:0016197 127 48 0,000 0,23325011 0,24796781 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,23325011 0,24785995 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,23325011 0,24775218 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,23325011 0,24764451 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,23325011 0,24753693 ! methylation GO:0032259 97 48 0,000 0,23325011 0,24742945 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,23748391 0,25181128 ! JNK cascade GO:0007254 106 49 0,000 0,23748391 0,25170204 ! protein homooligomerization GO:0051260 84 49 0,000 0,23748391 0,25159289 ! regulation of ion transport GO:0043269 86 50 0,000 0,24169445 0,25594259 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,24169445 0,25583169 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,24169445 0,2557209 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,24169445 0,25561019 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,24169445 0,25549959 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,24169445 0,25538908 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,24588186 0,25970142 ! viral infectious cycle GO:0019058 104 51 0,000 0,24588186 0,25958919 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,24588186 0,25947706 ! peptide metabolic process GO:0006518 80 51 0,000 0,24588186 0,25936502 ! positive regulation of binding GO:0051099 88 52 0,000 0,25004626 0,26364395 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,25004626 0,26353021 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,25004626 0,26341657 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,25004626 0,26330303 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,25004626 0,26318958 ! histone modification GO:0016570 104 52 0,000 0,25004626 0,26307624 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,25004626 0,26296299 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,25004626 0,26284984 ! amino acid activation GO:0043038 98 52 0,000 0,25004626 0,26273678 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,25418779 0,26697367 ! inner ear development GO:0048839 89 53 0,000 0,25418779 0,26685894 ! chromatin remodeling GO:0006338 122 53 0,000 0,25418779 0,26674431 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,25418779 0,26662978 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,25418779 0,26651535 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,25830655 0,27071768 ! neuromuscular process GO:0050905 107 54 0,000 0,25830655 0,27060159 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,25830655 0,2704856 ! membrane fusion GO:0006944 122 54 0,000 0,25830655 0,27036971 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,25830655 0,27025392 ! covalent chromatin modification GO:0016569 115 54 0,000 0,25830655 0,27013823 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,25830655 0,27002264 ! regulation of cell shape GO:0008360 142 54 0,000 0,25830655 0,26990715 ! RNA catabolic process GO:0006401 103 55 0,000 0,26240269 0,27407002 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,26240269 0,2739529 ! cell maturation GO:0048469 107 55 0,000 0,26240269 0,27383587 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,26240269 0,27371895 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,26647632 0,27784962 ! glucose catabolic process GO:0006007 88 56 0,000 0,26647632 0,27773108 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,26647632 0,27761265 ! regulation of DNA replication GO:0006275 105 56 0,000 0,26647632 0,27749431 ! RNA elongation GO:0006354 90 56 0,000 0,26647632 0,27737608 ! chloride transport GO:0006821 102 57 0,000 0,27052757 0,28147311 ! heart morphogenesis GO:0003007 105 57 0,000 0,27052757 0,28135328 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,27052757 0,28123355 ! regulation of actin filament length GO:0030832 118 58 0,000 0,27455655 0,28530058 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,27455655 0,28517928 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,27455655 0,28505808 ! gastrulation GO:0007369 122 58 0,000 0,27455655 0,28493698 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,27455655 0,28481599 ! maintenance of location GO:0051235 124 58 0,000 0,27455655 0,2846951 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,28254823 0,29285758 ! lipid modification GO:0030258 112 60 0,000 0,28254823 0,29273338 ! regulation of endocytosis GO:0030100 104 60 0,000 0,28254823 0,29260929 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,28254823 0,2924853 ! adult behavior GO:0030534 104 60 0,000 0,28254823 0,29236142 ! positive regulation of secretion GO:0051047 110 61 0,000 0,28651115 0,29633647 ! regulation of cellular component size GO:0032535 125 61 0,000 0,28651115 0,29621107 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,28651115 0,29608577 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,28651115 0,29596057 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,28651115 0,29583548 ! proton transport GO:0015992 117 61 0,000 0,28651115 0,2957105 ! viral reproductive process GO:0022415 132 62 0,000 0,2904523 0,2996516 ! tRNA processing GO:0008033 102 62 0,000 0,2904523 0,29952511 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,29437179 0,30343894 ! mesoderm development GO:0007498 128 63 0,000 0,29437179 0,30331096 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,29437179 0,30318309 ! hydrogen transport GO:0006818 121 64 0,000 0,29826974 0,30706826 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,29826974 0,30693891 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,29826974 0,30680968 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,30214627 0,31066639 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,30600149 0,31449795 ! activation of MAPK activity GO:0000187 124 67 0,000 0,30983552 0,31830453 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,30983552 0,31817073 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,30983552 0,31803705 ! hexose catabolic process GO:0019320 113 68 0,000 0,31364847 0,32181572 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,31364847 0,32168061 ! viral reproduction GO:0016032 142 68 0,000 0,31364847 0,32154562 ! cell projection assembly GO:0030031 138 68 0,000 0,31364847 0,32141075 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,31744047 0,3251602 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,31744047 0,32502392 ! developmental maturation GO:0021700 128 69 0,000 0,31744047 0,32488776 ! single fertilization GO:0007338 83 69 0,000 0,31744047 0,32475171 ! cell redox homeostasis GO:0045454 114 70 0,000 0,32121163 0,32847216 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,32496205 0,33216832 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,32869186 0,33584032 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,32869186 0,33569992 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,33240116 0,33934644 ! regulation of immune effector process GO:0002697 156 73 0,000 0,33240116 0,33920469 ! amino acid transport GO:0006865 148 74 0,000 0,33609007 0,3428259 ! transition metal ion transport GO:0000041 143 75 0,000 0,3397587 0,34642342 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,34340716 0,34999737 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,34340716 0,34985142 ! amine catabolic process GO:0009310 136 77 0,000 0,34703557 0,35340054 ! neurotransmitter transport GO:0006836 142 77 0,000 0,34703557 0,35325329 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,34703557 0,35310616 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,34703557 0,35295915 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,34703557 0,35281227 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,34703557 0,35266551 ! regulation of catabolic process GO:0009894 173 77 0,000 0,34703557 0,35251887 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,35064402 0,3560363 ! antigen processing and presentation GO:0019882 117 78 0,000 0,35064402 0,35588838 ! fertilization GO:0009566 99 78 0,000 0,35064402 0,35574059 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,35064402 0,35559292 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,35423263 0,35908312 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,35423263 0,35893419 ! protein oligomerization GO:0051259 149 79 0,000 0,35423263 0,35878537 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,35780152 0,36224994 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,36135077 0,36569177 ! exocytosis GO:0006887 153 83 0,000 0,36839085 0,37266205 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,36839085 0,3725078 ! inorganic anion transport GO:0015698 156 83 0,000 0,36839085 0,37235368 ! digestion GO:0007586 130 84 0,000 0,37188188 0,37572681 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,37535371 0,37907776 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,37880645 0,38240668 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,3822402 0,38571368 ! alcohol catabolic process GO:0046164 142 87 0,000 0,3822402 0,38555442 ! nucleosome assembly GO:0006334 126 87 0,000 0,3822402 0,3853953 ! cellular respiration GO:0045333 143 88 0,000 0,38565507 0,38867794 ! amine biosynthetic process GO:0009309 146 88 0,000 0,38565507 0,38851766 ! sensory perception of smell GO:0007608 117 88 0,000 0,38565507 0,38835751 ! chromatin assembly GO:0031497 128 88 0,000 0,38565507 0,3881975 ! cellular defense response GO:0006968 123 89 0,000 0,38905115 0,39145468 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,39242856 0,39469039 ! defense response to bacterium GO:0042742 112 91 0,000 0,39578739 0,39790477 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,39912775 0,40109794 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,40244973 0,40427002 ! amine transport GO:0015837 181 93 0,000 0,40244973 0,40410386 ! vitamin metabolic process GO:0006766 153 93 0,000 0,40244973 0,40393784 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,40575344 0,40708651 ! sterol metabolic process GO:0016125 166 94 0,000 0,40575344 0,4069194 ! nucleosome organization GO:0034728 143 95 0,000 0,40903898 0,41004605 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,40903898 0,40987786 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,40903898 0,40970981 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,40903898 0,4095419 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,41555593 0,41589641 ! mRNA transport GO:0051028 185 100 0,000 0,42519754 0,42537166 ! hormone metabolic process GO:0042445 171 100 0,000 0,42519754 0,42519754