pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6885-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 5 5 3,000 2,384E-08 5,483E-05 ! induction of positive chemotaxis GO:0050930 14 8 3,000 3,272E-07 3,763E-04 ! positive regulation of locomotion GO:0040017 35 20 4,000 5,499E-07 4,216E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! natural killer cell mediated immunity GO:0002228 13 9 3,000 5,852E-07 3,365E-04 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of chemotaxis GO:0050920 36 21 4,000 7,168E-07 3,297E-04 ! regulation of behavior GO:0050795 38 22 4,000 9,214E-07 3,532E-04 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 1,513E-06 4,97E-04 GO:0050927|positive regulation of positive chemotaxis, ! leukocyte mediated cytotoxicity GO:0001909 17 11 3,000 1,513E-06 4,349E-04 ! cell killing GO:0001906 20 14 3,000 4,499E-06 1,15E-03 ! polyol catabolic process GO:0046174 7 5 2,000 5,754E-06 1,323E-03 GO:0019405|alditol catabolic process, ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 2,000 5,754E-06 1,203E-03 ! axonal fasciculation GO:0007413 9 6 2,000 1,144E-05 2,192E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 1,34E-05 2,37E-03 ! peptide cross-linking GO:0018149 31 18 3,000 1,34E-05 2,201E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,989E-05 3,05E-03 ! neuroblast proliferation GO:0007405 13 7 2,000 1,989E-05 2,859E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 2,000 1,989E-05 2,691E-03 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 6,000 2,01E-05 2,568E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 4,000 2,038E-05 2,467E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 2,038E-05 2,344E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 2,922E-05 3,2E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 3,163E-05 3,307E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 3,163E-05 3,163E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 2,000 3,163E-05 3,031E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 3,163E-05 2,91E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 4,000 3,659E-05 3,237E-03 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 3,752E-05 3,196E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 4,715E-05 3,873E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 5,291E-05 4,196E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein modification process GO:0031400 50 26 3,000 6,212E-05 4,763E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 2,000 6,694E-05 4,967E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 6,756E-05 4,856E-03 ! microtubule cytoskeleton organization GO:0000226 120 84 5,000 7,564E-05 5,272E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 2,000 9,148E-05 6,188E-03 ! cellular carbohydrate catabolic process GO:0044275 13 11 2,000 9,148E-05 6,011E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 9,148E-05 5,844E-03 ! regulation of leukocyte migration GO:0002685 24 11 2,000 9,148E-05 5,686E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 9,148E-05 5,537E-03 GO:0010829|negative regulation of glucose transport, ! spindle organization GO:0007051 37 30 3,000 1,109E-04 6,542E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 1,156E-04 6,649E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 2,000 1,212E-04 6,8E-03 ! negative regulation of kinase activity GO:0033673 100 58 4,000 1,257E-04 6,884E-03 ! angiogenesis GO:0001525 149 95 5,000 1,499E-04 8,02E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,566E-04 8,187E-03 ! regulation of monooxygenase activity GO:0032768 26 13 2,000 1,566E-04 8,005E-03 ! negative regulation of transferase activity GO:0051348 105 61 4,000 1,599E-04 7,997E-03 ! establishment or maintenance of cell polarity GO:0007163 61 34 3,000 1,829E-04 8,95E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,981E-04 9,492E-03 ! regulation of survival gene product expression GO:0045884 20 15 2,000 2,461E-04 0,01155174 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 2,461E-04 0,01132071 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 2,461E-04 0,01109873 ! neuron recognition GO:0008038 22 15 2,000 2,461E-04 0,0108853 ! fructose metabolic process GO:0006000 20 16 2,000 3,01E-04 0,01306365 ! neutrophil chemotaxis GO:0030593 21 16 2,000 3,01E-04 0,01282173 ! negative regulation of translation GO:0017148 22 16 2,000 3,01E-04 0,01258861 ! positive regulation of phosphorylation GO:0042327 102 70 4,000 3,063E-04 0,01257818 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 4,000 3,493E-04 0,01409492 GO:0045937|positive regulation of phosphate metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 2,000 3,633E-04 0,01440638 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 3,633E-04 0,0141622 ! peptidyl-serine modification GO:0018209 27 17 2,000 3,633E-04 0,01392616 ! response to oxygen levels GO:0070482 137 74 4,000 3,968E-04 0,01496117 ! regulation of glucose import GO:0046324 21 18 2,000 4,333E-04 0,01607291 GO:0010827|regulation of glucose transport, ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 5,113E-04 0,01866821 ! regulation of endothelial cell migration GO:0010594 40 19 2,000 5,113E-04 0,01837652 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 2,000 5,113E-04 0,01809381 ! response to UV GO:0009411 75 46 3,000 5,952E-04 0,02074154 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 5,979E-04 0,02052456 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 5,979E-04 0,02022273 ! alditol metabolic process GO:0019400 24 20 2,000 5,979E-04 0,01992965 ! negative regulation of bone resorption GO:0045779 10 5 1,000 6,907E-04 0,02269458 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 6,907E-04 0,02237494 ! apoptotic cell clearance GO:0043277 13 5 1,000 6,907E-04 0,02206418 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 1,000 6,907E-04 0,02176193 ! anagen GO:0042640 6 5 1,000 6,907E-04 0,02146785 ! skeletal myofibril assembly GO:0014866 7 5 1,000 6,907E-04 0,02118161 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 6,907E-04 0,02090291 ! microvillus organization GO:0032528 7 5 1,000 6,907E-04 0,02063144 GO:0030033|microvillus assembly, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 1,000 6,907E-04 0,02036693 ! response to food GO:0032094 5 5 1,000 6,907E-04 0,02010912 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 1,000 6,907E-04 0,01985776 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 6,907E-04 0,0196126 GO:0045686|negative regulation of glial cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 1,000 6,907E-04 0,01937342 ! positive regulation of blood coagulation GO:0030194 10 5 1,000 6,907E-04 0,01914001 ! dendrite development GO:0016358 35 21 2,000 6,933E-04 0,01898199 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 6,933E-04 0,01875867 ! integrin-mediated signaling pathway GO:0007229 81 49 3,000 7,579E-04 0,0202684 ! cell cycle arrest GO:0007050 150 86 4,000 7,915E-04 0,0209234 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 7,915E-04 0,02068563 ! interphase GO:0051325 159 88 4,000 8,784E-04 0,0227011 ! positive regulation of cell migration GO:0030335 92 51 3,000 8,823E-04 0,0225485 ! myelination GO:0042552 35 23 2,000 9,118E-04 0,02304626 ! cellular iron ion homeostasis GO:0006879 37 23 2,000 9,118E-04 0,02279575 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 1,03E-03 0,0254815 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 1,03E-03 0,02521042 ! neuron adhesion GO:0007158 9 6 1,000 1,03E-03 0,02494504 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,03E-03 0,0246852 ! mRNA stabilization GO:0048255 15 6 1,000 1,03E-03 0,02443071 GO:0043489|RNA stabilization, ! ER overload response GO:0006983 7 6 1,000 1,03E-03 0,02418142 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 1,03E-03 0,02393716 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 1,03E-03 0,02369779 ! negative regulation of translational initiation GO:0045947 7 6 1,000 1,03E-03 0,02346316 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 1,03E-03 0,02323313 ! negative regulation of focal adhesion formation GO:0051895 16 6 1,000 1,03E-03 0,02300756 ! gas homeostasis GO:0033483 11 6 1,000 1,03E-03 0,02278634 ! hair follicle maturation GO:0048820 7 6 1,000 1,03E-03 0,02256933 ! regulation of macrophage activation GO:0043030 11 6 1,000 1,03E-03 0,02235641 ! glycolipid catabolic process GO:0019377 13 6 1,000 1,03E-03 0,02214747 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 1,000 1,03E-03 0,0219424 ! removal of superoxide radicals GO:0019430 10 6 1,000 1,03E-03 0,02174109 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,03E-03 0,02154345 ! positive regulation of coagulation GO:0050820 11 6 1,000 1,03E-03 0,02134936 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,036E-03 0,02126886 ! regulation of endothelial cell proliferation GO:0001936 46 24 2,000 1,036E-03 0,02108064 ! sperm motility GO:0030317 27 24 2,000 1,036E-03 0,02089572 ! negative regulation of cell development GO:0010721 56 24 2,000 1,036E-03 0,02071402 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 39 24 2,000 1,036E-03 0,02053545 ! glutathione metabolic process GO:0006749 29 24 2,000 1,036E-03 0,02035993 ! iron ion homeostasis GO:0055072 39 25 2,000 1,17E-03 0,02279959 ! positive regulation of cell motion GO:0051272 99 56 3,000 1,255E-03 0,02426403 ! regulation of response to external stimulus GO:0032101 139 96 4,000 1,299E-03 0,02489851 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 2,000 1,314E-03 0,02498042 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 2,000 1,314E-03 0,02477566 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 1,435E-03 0,02682432 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,435E-03 0,026608 ! microtubule bundle formation GO:0001578 8 7 1,000 1,435E-03 0,02639513 ! T-helper 1 type immune response GO:0042088 11 7 1,000 1,435E-03 0,02618565 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 1,000 1,435E-03 0,02597946 ! rRNA modification GO:0000154 12 7 1,000 1,435E-03 0,0257765 ! cardiac muscle cell development GO:0055013 9 7 1,000 1,435E-03 0,02557668 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 1,000 1,435E-03 0,02537993 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 1,435E-03 0,02518619 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 1,435E-03 0,02499539 ! regulation of lipid transport GO:0032368 13 7 1,000 1,435E-03 0,02480746 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 1,000 1,435E-03 0,02462232 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 1,000 1,435E-03 0,02443994 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of translation GO:0006417 151 100 4,000 1,558E-03 0,02634513 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,636E-03 0,02745992 ! ensheathment of neurons GO:0007272 43 28 2,000 1,636E-03 0,02726094 GO:0008366|axon ensheathment, ! hexose biosynthetic process GO:0019319 35 29 2,000 1,813E-03 0,03000291 ! lymphocyte mediated immunity GO:0002449 88 62 3,000 1,834E-03 0,03012995 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,902E-03 0,03102794 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 1,902E-03 0,03080944 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,902E-03 0,03059399 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,902E-03 0,03038153 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,902E-03 0,030172 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 1,000 1,902E-03 0,02996534 ! ganglioside metabolic process GO:0001573 15 8 1,000 1,902E-03 0,0297615 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,902E-03 0,02956041 ! regulation of gliogenesis GO:0014013 20 8 1,000 1,902E-03 0,02936201 GO:0045685|regulation of glial cell differentiation, ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 1,902E-03 0,02916627 ! neuromuscular process controlling posture GO:0050884 11 8 1,000 1,902E-03 0,02897311 ! regulation of fibrinolysis GO:0051917 13 8 1,000 1,902E-03 0,0287825 ! negative regulation of organic acid transport GO:0032891 12 8 1,000 1,902E-03 0,02859438 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,902E-03 0,0284087 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 1,000 1,902E-03 0,02822542 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 1,902E-03 0,02804449 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 1,946E-03 0,02850382 ! regulation of microtubule-based process GO:0032886 58 30 2,000 2,002E-03 0,02914831 ! response to heat GO:0009408 41 30 2,000 2,002E-03 0,02896499 ! leukocyte chemotaxis GO:0030595 43 31 2,000 2,203E-03 0,03167305 GO:0060326|cell chemotaxis, ! axon guidance GO:0007411 99 66 3,000 2,309E-03 0,03298446 ! monosaccharide biosynthetic process GO:0046364 38 32 2,000 2,416E-03 0,03430707 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 1,000 2,432E-03 0,03431864 ! lung alveolus development GO:0048286 17 9 1,000 2,432E-03 0,03410938 ! motor axon guidance GO:0008045 14 9 1,000 2,432E-03 0,03390266 ! regulation of RNA splicing GO:0043484 14 9 1,000 2,432E-03 0,03369843 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 1,000 2,432E-03 0,03349664 ! localization within membrane GO:0051668 15 9 1,000 2,432E-03 0,03329725 ! regulation of neuron differentiation GO:0045664 107 67 3,000 2,44E-03 0,03320271 ! actomyosin structure organization GO:0031032 43 33 2,000 2,642E-03 0,03574211 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 2,88E-03 0,03873372 ! polyol metabolic process GO:0019751 44 34 2,000 2,88E-03 0,03850852 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 2,88E-03 0,03828593 ! leukocyte mediated immunity GO:0002443 99 71 3,000 3,014E-03 0,03983674 ! negative regulation of blood pressure GO:0045776 22 10 1,000 3,023E-03 0,03973675 ! regulation of B cell proliferation GO:0030888 15 10 1,000 3,023E-03 0,03951098 ! sulfate transport GO:0008272 12 10 1,000 3,023E-03 0,03928775 ! hippocampus development GO:0021766 19 10 1,000 3,023E-03 0,03906703 ! blood vessel remodeling GO:0001974 21 10 1,000 3,023E-03 0,03884878 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 3,023E-03 0,03863295 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 3,023E-03 0,03841951 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 3,023E-03 0,03820842 ! glucan biosynthetic process GO:0009250 13 10 1,000 3,023E-03 0,03799963 GO:0005978|glycogen biosynthetic process, ! phagocytosis, engulfment GO:0006911 20 10 1,000 3,023E-03 0,03779311 ! regulation of bone resorption GO:0045124 24 10 1,000 3,023E-03 0,03758882 ! negative regulation of axonogenesis GO:0050771 23 10 1,000 3,023E-03 0,03738673 ! regulation of action potential in neuron GO:0019228 54 35 2,000 3,131E-03 0,03850363 ! glycogen metabolic process GO:0005977 48 35 2,000 3,131E-03 0,03829882 ! response to hypoxia GO:0001666 132 72 3,000 3,17E-03 0,0385824 ! negative regulation of transport GO:0051051 116 73 3,000 3,333E-03 0,04034283 ! mitochondrion organization GO:0007005 104 73 3,000 3,333E-03 0,04013162 ! glucan metabolic process GO:0044042 49 36 2,000 3,394E-03 0,0406604 GO:0006073|cellular glucan metabolic process, ! detection of mechanical stimulus GO:0050982 15 11 1,000 3,675E-03 0,04379531 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 3,675E-03 0,04356956 ! regulated secretory pathway GO:0045055 14 11 1,000 3,675E-03 0,04334613 ! regulation of mRNA processing GO:0050684 18 11 1,000 3,675E-03 0,04312497 ! T cell homeostasis GO:0043029 20 11 1,000 3,675E-03 0,04290606 ! regulation of organic acid transport GO:0032890 17 11 1,000 3,675E-03 0,04268937 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 3,675E-03 0,04247485 GO:0042130|negative regulation of T cell proliferation, ! regulation of cell morphogenesis GO:0022604 140 76 3,000 3,853E-03 0,04430959 ! alcohol biosynthetic process GO:0046165 45 38 2,000 3,962E-03 0,04533152 ! carbohydrate biosynthetic process GO:0016051 97 77 3,000 4,038E-03 0,04597718 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 4,266E-03 0,04832886 ! negative regulation of cell projection organization GO:0031345 26 12 1,000 4,386E-03 0,04944722 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 4,386E-03 0,04920601 ! Golgi organization GO:0007030 18 12 1,000 4,386E-03 0,04896715 ! negative regulation of endothelial cell migration GO:0010596 21 12 1,000 4,386E-03 0,04873059 ! regulation of interleukin-12 production GO:0032655 16 12 1,000 4,386E-03 0,04849631 ! histone acetylation GO:0016573 23 12 1,000 4,386E-03 0,04826427 ! peptidyl-lysine modification GO:0018205 18 12 1,000 4,386E-03 0,04803444 ! response to gamma radiation GO:0010332 20 12 1,000 4,386E-03 0,04780679 ! regulation of mRNA stability GO:0043488 27 12 1,000 4,386E-03 0,04758128 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 2,000 4,583E-03 0,04949103 ! peptide metabolic process GO:0006518 56 40 2,000 4,583E-03 0,04925976 ! energy reserve metabolic process GO:0006112 59 41 2,000 4,915E-03 0,05257922 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 5,155E-03 0,05488788 ! lipid localization GO:0010876 24 13 1,000 5,155E-03 0,05463494 GO:0019915|lipid storage, ! response to hexose stimulus GO:0009746 19 13 1,000 5,155E-03 0,05438432 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 5,155E-03 0,05413599 ! regulation of RNA stability GO:0043487 28 13 1,000 5,155E-03 0,05388991 ! regulation of axon extension GO:0030516 23 13 1,000 5,155E-03 0,05364607 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 5,155E-03 0,05340442 ! lymphocyte homeostasis GO:0002260 24 13 1,000 5,155E-03 0,05316494 ! regulation of cell shape GO:0008360 78 42 2,000 5,261E-03 0,05401777 ! leukocyte migration GO:0050900 60 43 2,000 5,621E-03 0,05745912 ! response to insulin stimulus GO:0032868 63 43 2,000 5,621E-03 0,05720488 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 5,738E-03 0,05813972 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 5,981E-03 0,06033248 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 5,981E-03 0,06006902 ! heterophilic cell adhesion GO:0007157 29 14 1,000 5,981E-03 0,05980785 ! limbic system development GO:0021761 25 14 1,000 5,981E-03 0,05954894 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 5,981E-03 0,05929227 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 5,981E-03 0,05903779 GO:0031114|regulation of microtubule depolymerization, ! intermediate filament-based process GO:0045103 24 14 1,000 5,981E-03 0,0587855 ! axon cargo transport GO:0008088 27 14 1,000 5,981E-03 0,05853534 ! sphingolipid catabolic process GO:0030149 23 14 1,000 5,981E-03 0,05828731 GO:0046466|membrane lipid catabolic process, ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 5,981E-03 0,05804138 ! regulation of action potential GO:0001508 71 44 2,000 5,996E-03 0,05794058 ! negative regulation of cell migration GO:0030336 92 44 2,000 5,996E-03 0,05769815 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,996E-03 0,05745774 ! regulation of inflammatory response GO:0050727 60 44 2,000 5,996E-03 0,05721933 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 5,996E-03 0,05698288 ! positive regulation of cell cycle GO:0045787 77 45 2,000 6,385E-03 0,06043204 ! positive regulation of defense response GO:0031349 59 45 2,000 6,385E-03 0,06018437 ! vascular process in circulatory system GO:0003018 69 45 2,000 6,385E-03 0,05993872 ! cell recognition GO:0008037 58 45 2,000 6,385E-03 0,05969507 ! regulation of neurogenesis GO:0050767 153 89 3,000 6,744E-03 0,06279517 ! lipid phosphorylation GO:0046834 23 15 1,000 6,863E-03 0,0636492 ! adult walking behavior GO:0007628 25 15 1,000 6,863E-03 0,06339358 ! positive regulation of proteolysis GO:0045862 19 15 1,000 6,863E-03 0,06314001 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 6,863E-03 0,06288845 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 6,863E-03 0,06263889 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 6,863E-03 0,06239131 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 6,863E-03 0,06214568 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 6,863E-03 0,06190197 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 6,863E-03 0,06166016 ! negative regulation of immune system process GO:0002683 73 47 2,000 7,207E-03 0,06450291 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 7,207E-03 0,06425289 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 2,000 7,207E-03 0,06400481 ! sulfur metabolic process GO:0006790 118 92 3,000 7,57E-03 0,06696492 ! regulation of muscle contraction GO:0006937 69 48 2,000 7,641E-03 0,06733709 ! response to temperature stimulus GO:0009266 62 48 2,000 7,641E-03 0,06708008 ! cellular polysaccharide metabolic process GO:0044264 63 48 2,000 7,641E-03 0,06682502 ! protein amino acid acetylation GO:0006473 28 16 1,000 7,8E-03 0,06795868 ! patterning of blood vessels GO:0001569 24 16 1,000 7,8E-03 0,06770223 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 7,86E-03 0,06795826 ! polysaccharide metabolic process GO:0005976 129 93 3,000 7,86E-03 0,06770374 ! regulation of angiogenesis GO:0045765 94 49 2,000 8,09E-03 0,06943096 ! cartilage development GO:0051216 70 49 2,000 8,09E-03 0,06917285 ! electron transport chain GO:0022900 123 94 3,000 8,156E-03 0,06947947 ! response to light stimulus GO:0009416 153 96 3,000 8,772E-03 0,07444592 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 1,000 8,792E-03 0,07434495 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 8,792E-03 0,07407263 ! memory GO:0007613 25 17 1,000 8,792E-03 0,07380229 ! cell-substrate junction assembly GO:0007044 39 17 1,000 8,792E-03 0,07353392 ! neuromuscular junction development GO:0007528 23 17 1,000 8,792E-03 0,07326749 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 8,792E-03 0,07300299 ! negative regulation of cell motion GO:0051271 104 51 2,000 9,034E-03 0,07474069 ! positive regulation of translation GO:0045727 28 18 1,000 9,837E-03 0,08109316 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 9,837E-03 0,08080354 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 9,837E-03 0,08051598 ! response to carbohydrate stimulus GO:0009743 24 18 1,000 9,837E-03 0,08023046 ! heart process GO:0003015 27 18 1,000 9,837E-03 0,07994696 GO:0060047|heart contraction, ! somitogenesis GO:0001756 24 18 1,000 9,837E-03 0,07966546 ! detection of chemical stimulus GO:0009593 26 18 1,000 9,837E-03 0,07938593 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 9,837E-03 0,07910836 ! negative regulation of T cell activation GO:0050868 25 18 1,000 9,837E-03 0,07883272 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 0,01093408 0,0873208 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 0,01093408 0,08701865 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 0,01093408 0,08671859 ! response to alkaloid GO:0043279 32 19 1,000 0,01093408 0,08642058 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 0,01093408 0,08612462 ! apoptotic nuclear changes GO:0030262 24 19 1,000 0,01093408 0,08583068 ! vasodilation GO:0042311 33 19 1,000 0,01093408 0,08553874 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 0,01093408 0,08524878 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 0,01093408 0,08496078 ! leukotriene biosynthetic process GO:0019370 26 19 1,000 0,01093408 0,08467471 GO:0043450|alkene biosynthetic process, ! negative regulation of response to stimulus GO:0048585 80 56 2,000 0,01166496 0,09003161 ! iron ion transport GO:0006826 37 20 1,000 0,01208255 0,09294268 ! microtubule-based transport GO:0010970 37 20 1,000 0,01208255 0,09263287 ! pallium development GO:0021543 38 20 1,000 0,01208255 0,09232512 ! neuromuscular process controlling balance GO:0050885 48 20 1,000 0,01208255 0,09201941 ! positive regulation of B cell activation GO:0050871 31 20 1,000 0,01208255 0,09171571 ! actin filament-based movement GO:0030048 34 20 1,000 0,01208255 0,09141402 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 0,0122385 0,09229029 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 0,01328142 0,09982768 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 0,01328142 0,09950251 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 1,000 0,01328142 0,09917945 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01328142 0,09885848 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01328142 0,09853958 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 1,000 0,01328142 0,09822273 GO:0060415|muscle tissue morphogenesis, ! leukotriene metabolic process GO:0006691 28 21 1,000 0,01328142 0,09790791 ! glycosphingolipid metabolic process GO:0006687 33 21 1,000 0,01328142 0,09759511 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 0,01328142 0,0972843 ! negative regulation of cytokine production GO:0001818 31 21 1,000 0,01328142 0,09697546 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 0,01328142 0,09666857 GO:0006099|tricarboxylic acid cycle, ! lung development GO:0030324 94 59 2,000 0,01343345 0,09746667 ! regulation of heart contraction GO:0008016 91 60 2,000 0,014055 0,10165563 ! regulation of homeostatic process GO:0032844 105 60 2,000 0,014055 0,10133696 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 0,01452978 0,10443283 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01452978 0,10410749 ! leukocyte adhesion GO:0007159 38 22 1,000 0,01452978 0,10378418 ! molting cycle process GO:0022404 40 22 1,000 0,01452978 0,10346286 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 1,000 0,01452978 0,10314353 ! vasculogenesis GO:0001570 33 22 1,000 0,01452978 0,10282617 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,01452978 0,10251075 GO:0010810|regulation of cell-substrate adhesion, ! lysosome organization GO:0007040 37 22 1,000 0,01452978 0,10219726 ! coenzyme catabolic process GO:0009109 33 22 1,000 0,01452978 0,10188568 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01452978 0,101576 ! regulation of blood coagulation GO:0030193 34 22 1,000 0,01452978 0,1012682 ! cellular alkene metabolic process GO:0043449 29 22 1,000 0,01452978 0,10096225 ! respiratory tube development GO:0030323 99 62 2,000 0,01534649 0,10631605 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01582673 0,10931377 ! acetyl-CoA metabolic process GO:0006084 33 23 1,000 0,01582673 0,10898648 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,01582673 0,10866115 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 1,000 0,01582673 0,10833775 ! glycolipid metabolic process GO:0006664 36 23 1,000 0,01582673 0,10801628 ! negative regulation of cell size GO:0045792 108 64 2,000 0,01670282 0,11365823 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 0,01670282 0,11332295 ! respiratory system development GO:0060541 100 64 2,000 0,01670282 0,11298965 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 0,01717137 0,11581864 ! superoxide metabolic process GO:0006801 32 24 1,000 0,01717137 0,11547999 ! vacuole organization GO:0007033 39 24 1,000 0,01717137 0,11514331 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 0,01717137 0,11480859 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 1,000 0,01856282 0,12375213 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01856282 0,12339447 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 0,01856282 0,12303886 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,02000021 0,13218527 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,02000021 0,13180652 ! post-embryonic development GO:0009791 42 26 1,000 0,02000021 0,13142993 ! regulation of coagulation GO:0050818 39 26 1,000 0,02000021 0,13105548 ! activation of protein kinase activity GO:0032147 102 69 2,000 0,020379 0,13315821 ! acute-phase response GO:0006953 42 27 1,000 0,02148267 0,13997207 ! myofibril assembly GO:0030239 36 27 1,000 0,02148267 0,13957667 GO:0055002|striated muscle cell development, ! response to ionizing radiation GO:0010212 47 27 1,000 0,02148267 0,1391835 ! cofactor catabolic process GO:0051187 45 27 1,000 0,02148267 0,13879253 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,02148267 0,13840376 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,02148267 0,13801715 ! icosanoid biosynthetic process GO:0046456 42 28 1,000 0,02300936 0,14741375 ! cell junction assembly GO:0034329 56 28 1,000 0,02300936 0,14700427 ! regulation of systemic arterial blood pressure GO:0003073 47 28 1,000 0,02300936 0,14659705 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,02300936 0,14619209 ! BMP signaling pathway GO:0030509 40 28 1,000 0,02300936 0,14578936 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,02300936 0,14538884 ! placenta development GO:0001890 37 28 1,000 0,02300936 0,14499051 ! regulation of B cell activation GO:0050864 42 28 1,000 0,02300936 0,14459436 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 0,02446455 0,15332009 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,02457945 0,15362155 ! regulation of axonogenesis GO:0050770 51 29 1,000 0,02457945 0,15320523 ! muscle cell development GO:0055001 38 29 1,000 0,02457945 0,15279116 ! telencephalon development GO:0021537 52 29 1,000 0,02457945 0,15237933 ! ceramide metabolic process GO:0006672 43 30 1,000 0,0261921 0,16194039 ! adult locomotory behavior GO:0008344 47 30 1,000 0,0261921 0,16150623 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,0261921 0,1610744 ! mammary gland development GO:0030879 57 31 1,000 0,02784649 0,17079183 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 0,02784649 0,1703376 ! segmentation GO:0035282 41 31 1,000 0,02784649 0,16988577 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 1,000 0,02784649 0,16943634 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02784649 0,16898928 ! RNA modification GO:0009451 40 31 1,000 0,02784649 0,16854457 ! positive regulation of protein modification process GO:0031401 107 78 2,000 0,02802783 0,16919689 ! cellular respiration GO:0045333 107 79 2,000 0,02895949 0,17436343 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02954183 0,17740526 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,02954183 0,17694327 ! alcohol catabolic process GO:0046164 104 80 2,000 0,02990744 0,17866782 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,03087165 0,18395024 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,03127732 0,18588587 ! ear morphogenesis GO:0042471 42 33 1,000 0,03127732 0,18540678 ! cell junction organization GO:0034330 63 33 1,000 0,03127732 0,18493016 ! sphingoid metabolic process GO:0046519 47 33 1,000 0,03127732 0,18445598 ! nucleus organization GO:0006997 49 33 1,000 0,03127732 0,18398423 ! regulation of proteolysis GO:0030162 50 33 1,000 0,03127732 0,18351488 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,03127732 0,18304792 ! cytokinesis GO:0000910 52 33 1,000 0,03127732 0,18258333 ! ossification GO:0001503 134 82 2,000 0,03185209 0,18546785 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 2,000 0,03185209 0,18499949 ! regulation of cell adhesion GO:0030155 159 83 2,000 0,03284872 0,19030744 ! regulation of neuron projection development GO:0010975 63 34 1,000 0,03305217 0,19100498 ! neuron migration GO:0001764 46 34 1,000 0,03305217 0,19052627 ! aerobic respiration GO:0009060 47 34 1,000 0,03305217 0,19004995 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,03305217 0,18957601 ! regulation of defense response GO:0031347 117 84 2,000 0,03386151 0,193735 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,0348656 0,19898481 ! polysaccharide biosynthetic process GO:0000271 47 35 1,000 0,0348656 0,19849227 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,0348656 0,19800217 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,0348656 0,19751448 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of membrane potential GO:0042391 128 85 2,000 0,03489041 0,19716941 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 0,03489041 0,19668615 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,03671685 0,2064762 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 1,000 0,03671685 0,2059726 ! tissue remodeling GO:0048771 62 36 1,000 0,03671685 0,20547145 ! heterocycle biosynthetic process GO:0018130 46 36 1,000 0,03671685 0,20497273 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,03699639 0,20603314 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,03699639 0,20553548 ! amino acid activation GO:0043038 52 37 1,000 0,03860518 0,2139564 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 0,04052982 0,22408314 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,04052982 0,22354577 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,04052982 0,22301097 ! phagocytosis GO:0006909 60 38 1,000 0,04052982 0,22247873 ! mesenchymal cell development GO:0014031 64 38 1,000 0,04052982 0,22194902 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 1,000 0,04052982 0,22142182 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,04134676 0,22534965 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,04134676 0,22481691 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,04134676 0,22428668 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,04134676 0,22375895 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,04134676 0,22323369 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,04134676 0,2227109 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,04134676 0,22219054 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,04134676 0,22167262 ! sleep GO:0030431 11 5 0,000 0,04134676 0,2211571 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,04134676 0,22064397 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,04134676 0,22013322 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,04134676 0,21962483 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,04134676 0,21911879 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,04134676 0,21861506 ! tongue development GO:0043586 6 5 0,000 0,04134676 0,21811365 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,04134676 0,21761454 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,04134676 0,2171177 ! cobalt ion transport GO:0006824 9 5 0,000 0,04134676 0,21662313 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,04134676 0,2161308 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,04134676 0,21564071 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,04134676 0,21515283 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,04134676 0,21466716 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,04134676 0,21418368 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,04134676 0,21370237 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,04134676 0,21322321 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,04134676 0,2127462 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,04134676 0,21227132 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,04134676 0,21179856 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,04134676 0,21132789 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,04134676 0,21085932 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,04134676 0,21039282 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,04134676 0,20992837 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,04134676 0,20946598 ! malate metabolic process GO:0006108 7 5 0,000 0,04134676 0,20900561 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,04134676 0,20854726 ! behavioral response to pain GO:0048266 7 5 0,000 0,04134676 0,20809093 ! clathrin coat assembly GO:0048268 11 5 0,000 0,04134676 0,20763658 ! phototransduction, visible light GO:0007603 6 5 0,000 0,04134676 0,20718421 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,04134676 0,20673381 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,04134676 0,20628536 ! mating behavior GO:0007617 6 5 0,000 0,04134676 0,20583886 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,04134676 0,20539428 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,04134676 0,20495162 ! rhythmic behavior GO:0007622 12 5 0,000 0,04134676 0,20451087 ! copulation GO:0007620 7 5 0,000 0,04134676 0,204072 ! glial cell fate commitment GO:0021781 12 5 0,000 0,04134676 0,20363502 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,04134676 0,2031999 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,04134676 0,20276664 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,04134676 0,20233522 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,04134676 0,20190563 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,04134676 0,20147787 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,04134676 0,20105191 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,04134676 0,20062775 ! response to protozoan GO:0001562 9 5 0,000 0,04134676 0,20020537 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,04134676 0,19978477 ! lymph vessel development GO:0001945 7 5 0,000 0,04134676 0,19936594 ! endochondral ossification GO:0001958 12 5 0,000 0,04134676 0,19894886 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,04134676 0,19853351 ! parathyroid gland development GO:0060017 8 5 0,000 0,04134676 0,1981199 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,04134676 0,19770801 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,04134676 0,19729783 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,04134676 0,19688934 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,04134676 0,19648255 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,04134676 0,19607743 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,04134676 0,19567398 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,04134676 0,19527218 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,04134676 0,19487203 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,04134676 0,19447352 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,04134676 0,19407664 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,04134676 0,19368137 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,04134676 0,19328771 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,04134676 0,19289564 ! ovulation GO:0030728 6 5 0,000 0,04134676 0,19250517 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,04134676 0,19211627 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,04134676 0,19172894 ! response to pH GO:0009268 9 5 0,000 0,04134676 0,19134316 ! proline biosynthetic process GO:0006561 6 5 0,000 0,04134676 0,19095894 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,04134676 0,19057626 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,04134676 0,19019511 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,04134676 0,18981547 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,04134676 0,18943736 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,04134676 0,18906074 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,04134676 0,18868562 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,04134676 0,18831199 ! nerve growth factor processing GO:0032455 7 5 0,000 0,04134676 0,18793983 ! urea metabolic process GO:0019627 6 5 0,000 0,04134676 0,18756914 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,04134676 0,18719991 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,04134676 0,18683213 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,04134676 0,18646579 ! neutrophil activation GO:0042119 5 5 0,000 0,04134676 0,18610089 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,04134676 0,18573741 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,04134676 0,18537535 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,04134676 0,18501469 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,04134676 0,18465544 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,04134676 0,18429758 ! forebrain neuron development GO:0021884 7 5 0,000 0,04134676 0,18394111 ! melanosome organization GO:0032438 7 5 0,000 0,04134676 0,18358601 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04134676 0,18323228 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,04134676 0,18287991 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,04134676 0,18252889 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,04134676 0,18217922 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,04134676 0,18183088 ! nucleoside transport GO:0015858 6 5 0,000 0,04134676 0,18148388 ! nucleoside salvage GO:0043174 7 5 0,000 0,04134676 0,1811382 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,04134676 0,18079383 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,04134676 0,18045076 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,04134676 0,180109 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,04134676 0,17976853 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,04134676 0,17942934 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,04134676 0,17909144 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,04134676 0,1787548 ! depyrimidination GO:0045008 8 5 0,000 0,04134676 0,17841942 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,04134676 0,1780853 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,04134676 0,17775244 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,04134676 0,17742081 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,04134676 0,17709041 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,04134676 0,17676125 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,04134676 0,17643331 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,04134676 0,17610658 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,04134676 0,17578106 ! monocyte differentiation GO:0030224 8 5 0,000 0,04134676 0,17545674 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,04134676 0,17513361 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,04134676 0,17481168 ! centrosome duplication GO:0051298 5 5 0,000 0,04134676 0,17449092 ! response to UV-C GO:0010225 6 5 0,000 0,04134676 0,17417134 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,04134676 0,17385293 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,04134676 0,17353568 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of dendrite development GO:0050773 12 5 0,000 0,04134676 0,17321959 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,04134676 0,17290464 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,04134676 0,17259084 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,04134676 0,17227818 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,04134676 0,17196664 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,04134676 0,17165623 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,04134676 0,17134694 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,04134676 0,17103876 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,04134676 0,17073169 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,04134676 0,17042572 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,04134676 0,17012085 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,04134676 0,16981706 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,04134676 0,16951435 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,04134676 0,16921273 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,04134676 0,16891217 ! neural tube patterning GO:0021532 6 5 0,000 0,04134676 0,16861268 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,04134676 0,16831425 ! histone demethylation GO:0016577 9 5 0,000 0,04134676 0,16801688 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04134676 0,16772055 ! regulation of sterol transport GO:0032371 7 5 0,000 0,04134676 0,16742527 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,04134676 0,16713102 ! enteric nervous system development GO:0048484 8 5 0,000 0,04134676 0,16683781 ! establishment of planar polarity GO:0001736 6 5 0,000 0,04134676 0,16654563 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,04134676 0,16625446 ! muscle cell proliferation GO:0033002 8 5 0,000 0,04134676 0,16596432 ! transcription termination GO:0006353 8 5 0,000 0,04134676 0,16567518 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,04134676 0,16538705 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,04134676 0,16509992 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,04134676 0,16481378 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,04134676 0,16452864 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,04134676 0,16424448 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,04134676 0,1639613 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,04134676 0,16367909 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,04134676 0,16339786 ! apical protein localization GO:0045176 6 5 0,000 0,04134676 0,16311759 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,04134676 0,16283828 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,04134676 0,16255992 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,04134676 0,16228251 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,04134676 0,16200605 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,04134676 0,16173053 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,04134676 0,16145595 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,04134676 0,16118229 ! glial cell migration GO:0008347 10 5 0,000 0,04134676 0,16090956 ! determination of adult lifespan GO:0008340 8 5 0,000 0,04134676 0,16063776 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,04134676 0,16036687 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04134676 0,16009689 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,04134676 0,15982782 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,04134676 0,15955965 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,04134676 0,15929238 ! neural plate development GO:0001840 6 5 0,000 0,04134676 0,15902601 ! regulation of sensory perception GO:0051931 6 5 0,000 0,04134676 0,15876052 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,04134676 0,15849592 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,04134676 0,1582322 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,04134676 0,15796936 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,04134676 0,15770738 ! sensory cilium assembly GO:0035058 6 5 0,000 0,04134676 0,15744628 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,04134676 0,15718604 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,04134676 0,15692665 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,04134676 0,15666813 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,04134676 0,15641045 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,04134676 0,15615362 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,04134676 0,15589763 ! organ regeneration GO:0031100 7 5 0,000 0,04134676 0,15564248 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,04134676 0,15538816 ! carnitine metabolic process GO:0009437 5 5 0,000 0,04134676 0,15513467 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,04134676 0,15488201 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,04134676 0,15463017 GO:0055081|anion homeostasis, ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,04249005 0,15864792 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,04249005 0,15839079 ! developmental growth GO:0048589 62 39 1,000 0,04249005 0,1581345 ! cell growth GO:0016049 61 39 1,000 0,04249005 0,15787903 ! synapse organization GO:0050808 55 39 1,000 0,04249005 0,15762439 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 0,04369594 0,1618368 ! carbohydrate catabolic process GO:0016052 121 93 2,000 0,04369594 0,16157661 ! response to calcium ion GO:0051592 58 40 1,000 0,04448514 0,16423087 ! regulation of tube size GO:0035150 60 40 1,000 0,04448514 0,16396768 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,04448514 0,16370533 ! double-strand break repair GO:0006302 67 40 1,000 0,04448514 0,16344382 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,04448514 0,16318314 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,04448514 0,1629233 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,04651438 0,17008438 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,04651438 0,16981441 ! glucose transport GO:0015758 52 41 1,000 0,04651438 0,16954529 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,04857706 0,17678359 ! cellular component disassembly GO:0022411 64 42 1,000 0,04857706 0,17650432 ! hexose transport GO:0008645 54 42 1,000 0,04857706 0,17622592 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,04857706 0,1759484 ! glycosaminoglycan metabolic process GO:0030203 63 42 1,000 0,04857706 0,17567175 ! icosanoid metabolic process GO:0006690 61 42 1,000 0,04857706 0,17539597 ! tRNA transcription GO:0009304 11 6 0,000 0,04941005 0,17812399 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04941005 0,17784524 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04941005 0,17756736 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04941005 0,17729034 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04941005 0,17701419 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04941005 0,17673889 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04941005 0,17646445 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04941005 0,17619086 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04941005 0,17591812 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04941005 0,17564622 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04941005 0,17537517 ! prostate gland development GO:0030850 9 6 0,000 0,04941005 0,17510494 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04941005 0,17483555 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04941005 0,17456699 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04941005 0,17429924 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04941005 0,17403232 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04941005 0,17376622 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04941005 0,17350093 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04941005 0,17323644 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04941005 0,17297277 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04941005 0,17270989 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04941005 0,17244781 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04941005 0,17218653 ! signal peptide processing GO:0006465 8 6 0,000 0,04941005 0,17192603 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04941005 0,17166633 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04941005 0,1714074 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04941005 0,17114926 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04941005 0,17089189 ! opsonization GO:0008228 8 6 0,000 0,04941005 0,1706353 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04941005 0,17037947 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04941005 0,17012441 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04941005 0,16987012 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04941005 0,16961658 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04941005 0,1693638 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04941005 0,16911177 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04941005 0,16886049 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04941005 0,16860995 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04941005 0,16836016 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04941005 0,16811111 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04941005 0,16786279 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04941005 0,1676152 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04941005 0,16736835 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04941005 0,16712222 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04941005 0,16687681 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04941005 0,16663212 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04941005 0,16638815 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04941005 0,16614489 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04941005 0,16590235 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04941005 0,16566051 ! thymic T cell selection GO:0045061 12 6 0,000 0,04941005 0,16541937 ! protein lipoylation GO:0009249 10 6 0,000 0,04941005 0,16517894 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04941005 0,1649392 ! pigment granule organization GO:0048753 11 6 0,000 0,04941005 0,16470016 ! drug transport GO:0015893 6 6 0,000 0,04941005 0,16446181 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04941005 0,16422414 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04941005 0,16398717 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04941005 0,16375088 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04941005 0,16351526 ! histidine metabolic process GO:0006547 6 6 0,000 0,04941005 0,16328033 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04941005 0,16304607 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04941005 0,16281247 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04941005 0,16257955 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04941005 0,1623473 ! adenohypophysis development GO:0021984 10 6 0,000 0,04941005 0,1621157 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04941005 0,16188477 ! hyperosmotic response GO:0006972 8 6 0,000 0,04941005 0,16165449 ! microtubule nucleation GO:0007020 10 6 0,000 0,04941005 0,16142487 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04941005 0,1611959 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04941005 0,16096757 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04941005 0,1607399 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04941005 0,16051286 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04941005 0,16028647 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,04941005 0,16006071 ! response to dietary excess GO:0002021 7 6 0,000 0,04941005 0,15983559 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04941005 0,15961111 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04941005 0,15938725 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04941005 0,15916402 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04941005 0,15894141 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04941005 0,15871942 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04941005 0,15849806 ! neuron apoptosis GO:0051402 8 6 0,000 0,04941005 0,15827731 ! organic alcohol transport GO:0015850 9 6 0,000 0,04941005 0,15805717 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04941005 0,15783765 ! male sex determination GO:0030238 9 6 0,000 0,04941005 0,15761873 ! carnitine transport GO:0015879 8 6 0,000 0,04941005 0,15740043 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04941005 0,15718272 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04941005 0,15696562 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04941005 0,15674911 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04941005 0,15653321 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04941005 0,15631789 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04941005 0,15610317 ! parturition GO:0007567 12 6 0,000 0,04941005 0,15588904 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04941005 0,15567549 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04941005 0,15546253 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04941005 0,15525015 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04941005 0,15503835 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04941005 0,15482712 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04941005 0,15461647 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04941005 0,1544064 ! macrophage differentiation GO:0030225 10 6 0,000 0,04941005 0,15419689 ! astrocyte development GO:0014002 14 6 0,000 0,04941005 0,15398795 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04941005 0,15377958 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04941005 0,15357177 ! interaction with symbiont GO:0051702 8 6 0,000 0,04941005 0,15336452 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04941005 0,15315783 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04941005 0,15295169 ! eating behavior GO:0042755 6 6 0,000 0,04941005 0,15274611 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04941005 0,15254108 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04941005 0,15233661 ! response to copper ion GO:0046688 9 6 0,000 0,04941005 0,15213267 ! DNA topological change GO:0006265 8 6 0,000 0,04941005 0,15192929 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04941005 0,15172645 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04941005 0,15152414 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04941005 0,15132238 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04941005 0,15112115 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04941005 0,15092046 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04941005 0,1507203 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04941005 0,15052067 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04941005 0,15032157 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04941005 0,150123 ! Schwann cell development GO:0014044 14 6 0,000 0,04941005 0,14992494 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04941005 0,14972741 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04941005 0,1495304 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04941005 0,14933391 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04941005 0,14913794 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04941005 0,14894247 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04941005 0,14874752 ! histone ubiquitination GO:0016574 7 6 0,000 0,04941005 0,14855308 ! regulation of meiosis GO:0040020 10 6 0,000 0,04941005 0,14835915 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04941005 0,14816572 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04941005 0,1479728 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04941005 0,14778037 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04941005 0,14758845 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04941005 0,14739703 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04941005 0,1472061 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04941005 0,14701566 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04941005 0,14682572 ! receptor internalization GO:0031623 9 6 0,000 0,04941005 0,14663627 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04941005 0,1464473 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04941005 0,14625883 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04941005 0,14607083 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04941005 0,14588332 ! protein deubiquitination GO:0016579 8 6 0,000 0,04941005 0,14569629 GO:0070646|protein modification by small protein removal, ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04941005 0,14550974 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04941005 0,14532367 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04941005 0,14513807 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04941005 0,14495294 ! midbrain development GO:0030901 6 6 0,000 0,04941005 0,14476829 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04941005 0,14458411 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04941005 0,14440039 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04941005 0,14421714 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04941005 0,14403436 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04941005 0,14385203 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04941005 0,14367017 GO:0010828|positive regulation of glucose transport, ! adult feeding behavior GO:0008343 6 6 0,000 0,04941005 0,14348877 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04941005 0,14330783 ! blastocyst growth GO:0001832 15 6 0,000 0,04941005 0,14312734 ! pigment granule transport GO:0051904 12 6 0,000 0,04941005 0,1429473 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04941005 0,14276772 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04941005 0,14258859 ! catecholamine transport GO:0051937 7 6 0,000 0,04941005 0,14240991 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04941005 0,14223167 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04941005 0,14205388 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04941005 0,14187654 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,04941005 0,14169964 ! protein prenylation GO:0018342 10 6 0,000 0,04941005 0,14152317 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04941005 0,14134715 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04941005 0,14117156 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04941005 0,14099641 ! positive regulation of binding GO:0051099 59 43 1,000 0,05067247 0,14441969 ! neuromuscular process GO:0050905 79 43 1,000 0,05067247 0,14424096 ! activation of caspase activity GO:0006919 65 43 1,000 0,05067247 0,14406266 ! protein localization in organelle GO:0033365 161 100 2,000 0,05222158 0,1482835 ! regulation of cell projection organization GO:0031344 83 44 1,000 0,05279995 0,14974091 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,05279995 0,1495565 ! regulation of translational initiation GO:0006446 64 45 1,000 0,05495879 0,15547997 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,05714834 0,16147565 ! cell redox homeostasis GO:0045454 63 46 1,000 0,05714834 0,16127752 ! unsaturated fatty acid metabolic process GO:0033559 66 46 1,000 0,05714834 0,16107988 ! histone modification GO:0016570 68 46 1,000 0,05714834 0,16088272 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05740597 0,16141042 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05740597 0,16121334 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05740597 0,16101674 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05740597 0,16082062 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05740597 0,16062497 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05740597 0,1604298 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05740597 0,16023511 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05740597 0,16004088 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05740597 0,15984713 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05740597 0,15965384 ! reproductive behavior GO:0019098 12 7 0,000 0,05740597 0,15946102 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05740597 0,15926867 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,05740597 0,15907678 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05740597 0,15888535 ! oligopeptide transport GO:0006857 11 7 0,000 0,05740597 0,15869438 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05740597 0,15850387 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05740597 0,15831382 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05740597 0,15812422 ! RNA methylation GO:0001510 11 7 0,000 0,05740597 0,15793508 ! pericardium development GO:0060039 8 7 0,000 0,05740597 0,15774639 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05740597 0,15755815 ! fibril organization GO:0043206 13 7 0,000 0,05740597 0,15737035 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05740597 0,15718301 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05740597 0,15699611 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05740597 0,15680965 ! lipoprotein transport GO:0042953 9 7 0,000 0,05740597 0,15662364 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05740597 0,15643806 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05740597 0,15625293 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05740597 0,15606823 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05740597 0,15588397 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05740597 0,15570015 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05740597 0,15551676 ! chemosensory behavior GO:0007635 9 7 0,000 0,05740597 0,1553338 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05740597 0,15515127 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05740597 0,15496916 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05740597 0,15478749 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05740597 0,15460624 ! reflex GO:0060004 12 7 0,000 0,05740597 0,15442541 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05740597 0,15424501 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05740597 0,15406503 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05740597 0,15388546 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05740597 0,15370632 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05740597 0,15352759 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05740597 0,15334928 ! spinal cord patterning GO:0021511 7 7 0,000 0,05740597 0,15317138 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05740597 0,15299389 ! adrenal gland development GO:0030325 17 7 0,000 0,05740597 0,15281681 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05740597 0,15264015 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05740597 0,15246389 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05740597 0,15228804 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05740597 0,15211259 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05740597 0,15193755 ! endosome organization GO:0007032 10 7 0,000 0,05740597 0,1517629 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05740597 0,15158866 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05740597 0,15141482 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05740597 0,15124138 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,05740597 0,15106834 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05740597 0,15089569 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05740597 0,15072343 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05740597 0,15055157 ! galactose metabolic process GO:0006012 10 7 0,000 0,05740597 0,1503801 ! vesicle fusion GO:0006906 15 7 0,000 0,05740597 0,15020902 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05740597 0,15003833 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05740597 0,14986802 ! organ growth GO:0035265 11 7 0,000 0,05740597 0,1496981 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05740597 0,14952857 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05740597 0,14935942 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05740597 0,14919065 ! retinol metabolic process GO:0042572 9 7 0,000 0,05740597 0,14902226 ! behavioral fear response GO:0001662 13 7 0,000 0,05740597 0,14885426 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05740597 0,14868663 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05740597 0,14851938 ! protein heterooligomerization GO:0051291 10 7 0,000 0,05740597 0,1483525 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05740597 0,148186 ! response to UV-B GO:0010224 11 7 0,000 0,05740597 0,14801987 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05740597 0,14785412 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05740597 0,14768873 ! intermediate filament organization GO:0045109 11 7 0,000 0,05740597 0,14752372 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05740597 0,14735907 ! fibrinolysis GO:0042730 9 7 0,000 0,05740597 0,14719479 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05740597 0,14703088 ! B cell lineage commitment GO:0002326 17 7 0,000 0,05740597 0,14686733 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05740597 0,14670414 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05740597 0,14654132 ! response to tropane GO:0014073 13 7 0,000 0,05740597 0,14637885 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,05740597 0,14621675 ! melanosome localization GO:0032400 10 7 0,000 0,05740597 0,14605501 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05740597 0,14589362 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05740597 0,14573259 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05740597 0,14557191 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05740597 0,14541159 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05740597 0,14525162 ! mast cell activation GO:0045576 9 7 0,000 0,05740597 0,14509201 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05740597 0,14493274 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05740597 0,14477382 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05740597 0,14461525 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05740597 0,14445703 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05740597 0,14429915 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05740597 0,14414162 ! T cell lineage commitment GO:0002360 12 7 0,000 0,05740597 0,14398443 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05740597 0,14382759 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05740597 0,14367108 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05740597 0,14351492 ! response to tumor cell GO:0002347 12 7 0,000 0,05740597 0,1433591 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05740597 0,14320361 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05740597 0,14304846 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,05740597 0,14289364 ! diuresis GO:0030146 12 7 0,000 0,05740597 0,14273916 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05740597 0,14258502 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05740597 0,1424312 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05740597 0,14227772 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05740597 0,14212457 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05740597 0,14197175 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05740597 0,14181926 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05740597 0,14166709 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05740597 0,14151525 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,05740597 0,14136373 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,05740597 0,14121254 ! lymph node development GO:0048535 9 7 0,000 0,05740597 0,14106167 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05740597 0,14091113 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05740597 0,1407609 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05740597 0,140611 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05740597 0,14046141 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05740597 0,14031214 ! ATP catabolic process GO:0006200 10 7 0,000 0,05740597 0,14016319 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05740597 0,14001456 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,05740597 0,13986624 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05740597 0,13971823 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05740597 0,13957054 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05740597 0,13942315 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05740597 0,13927608 ! muscle adaptation GO:0043500 12 7 0,000 0,05740597 0,13912932 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05740597 0,13898287 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05740597 0,13883673 ! retina homeostasis GO:0001895 9 7 0,000 0,05740597 0,13869089 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05740597 0,13854536 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05740597 0,13840013 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05740597 0,13825521 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05740597 0,13811059 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05740597 0,13796628 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05740597 0,13782226 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05740597 0,13767855 ! respiratory electron transport chain GO:0022904 59 47 1,000 0,05936793 0,14223567 ! covalent chromatin modification GO:0016569 75 47 1,000 0,05936793 0,14208766 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,06161692 0,14731695 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 65 48 1,000 0,06161692 0,14716398 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,06161692 0,14701132 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,06161692 0,14685897 ! aminoglycan metabolic process GO:0006022 72 49 1,000 0,06389465 0,15213012 ! sulfur compound biosynthetic process GO:0044272 62 49 1,000 0,06389465 0,1519728 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,06389465 0,1518158 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,06389465 0,15165913 ! germ cell development GO:0007281 68 49 1,000 0,06389465 0,15150278 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06533509 0,1547587 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06533509 0,15459948 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,06533509 0,15444059 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06533509 0,15428203 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06533509 0,15412379 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06533509 0,15396588 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06533509 0,15380829 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06533509 0,15365102 ! phosphate transport GO:0006817 10 8 0,000 0,06533509 0,15349407 ! N-glycan processing GO:0006491 12 8 0,000 0,06533509 0,15333745 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06533509 0,15318114 ! UTP metabolic process GO:0046051 8 8 0,000 0,06533509 0,15302515 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06533509 0,15286948 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06533509 0,15271412 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06533509 0,15255908 ! succinate metabolic process GO:0006105 14 8 0,000 0,06533509 0,15240436 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,06533509 0,15224995 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06533509 0,15209585 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06533509 0,15194206 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06533509 0,15178858 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06533509 0,15163542 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06533509 0,15148256 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,06533509 0,15133001 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06533509 0,15117776 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06533509 0,15102583 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06533509 0,15087419 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06533509 0,15072286 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06533509 0,15057184 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06533509 0,15042112 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06533509 0,1502707 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06533509 0,15012058 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06533509 0,14997075 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,06533509 0,14982123 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06533509 0,14967201 ! melanin metabolic process GO:0006582 12 8 0,000 0,06533509 0,14952308 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06533509 0,14937445 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06533509 0,14922611 ! macrophage activation GO:0042116 12 8 0,000 0,06533509 0,14907807 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06533509 0,14893032 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06533509 0,14878287 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06533509 0,1486357 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06533509 0,14848883 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06533509 0,14834225 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06533509 0,14819595 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06533509 0,14804995 ! ruffle organization GO:0031529 11 8 0,000 0,06533509 0,14790423 ! osteoblast development GO:0002076 13 8 0,000 0,06533509 0,1477588 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06533509 0,14761365 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06533509 0,14746879 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06533509 0,14732421 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06533509 0,14717992 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06533509 0,14703591 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06533509 0,14689218 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,06533509 0,14674873 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06533509 0,14660556 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06533509 0,14646267 ! brain morphogenesis GO:0048854 20 8 0,000 0,06533509 0,14632005 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06533509 0,14617772 ! segment specification GO:0007379 10 8 0,000 0,06533509 0,14603566 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,06533509 0,14589388 ! cellular extravasation GO:0045123 11 8 0,000 0,06533509 0,14575237 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06533509 0,14561114 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06533509 0,14547018 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06533509 0,14532949 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06533509 0,14518908 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06533509 0,14504893 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06533509 0,14490906 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06533509 0,14476946 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,06533509 0,14463012 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06533509 0,14449105 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06533509 0,14435225 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06533509 0,14421372 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06533509 0,14407545 ! icosanoid secretion GO:0032309 12 8 0,000 0,06533509 0,14393745 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,06533509 0,14379971 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06533509 0,14366223 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06533509 0,14352502 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06533509 0,14338807 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06533509 0,14325138 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06533509 0,14311495 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06533509 0,14297878 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06533509 0,14284287 ! sterol catabolic process GO:0016127 9 8 0,000 0,06533509 0,14270721 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06533509 0,14257182 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06533509 0,14243668 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06533509 0,1423018 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06533509 0,14216717 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06533509 0,14203279 ! prophase GO:0051324 11 8 0,000 0,06533509 0,14189867 ! S phase GO:0051320 8 8 0,000 0,06533509 0,14176481 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06533509 0,14163119 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,06533509 0,14149783 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06533509 0,14136472 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06533509 0,14123186 ! hormone catabolic process GO:0042447 13 8 0,000 0,06533509 0,14109925 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06533509 0,14096688 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06533509 0,14083477 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06533509 0,1407029 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06533509 0,14057128 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06533509 0,1404399 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06533509 0,14030877 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06533509 0,14017789 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06533509 0,14004725 ! regulation of embryonic development GO:0045995 16 8 0,000 0,06533509 0,13991685 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06533509 0,13978669 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06533509 0,13965678 ! ear development GO:0043583 72 50 1,000 0,06620049 0,14137524 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,06620049 0,1412441 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,06620049 0,14111319 ! lipid modification GO:0030258 73 50 1,000 0,06620049 0,14098253 ! positive regulation of growth GO:0045927 67 50 1,000 0,06620049 0,14085211 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,06620049 0,14072194 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,06853383 0,14554737 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,06853383 0,1454131 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,06853383 0,14527908 ! adult behavior GO:0030534 80 51 1,000 0,06853383 0,1451453 ! transition metal ion transport GO:0000041 74 52 1,000 0,07089403 0,15000576 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,07089403 0,14986788 ! aging GO:0007568 79 52 1,000 0,07089403 0,14973026 ! sphingolipid metabolic process GO:0006665 72 52 1,000 0,07089403 0,1495929 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,07319795 0,15431282 ! regulation of developmental growth GO:0048638 13 9 0,000 0,07319795 0,15417151 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,07319795 0,15403046 ! telencephalon cell migration GO:0022029 16 9 0,000 0,07319795 0,15388966 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,07319795 0,15374912 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07319795 0,15360884 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07319795 0,15346882 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,07319795 0,15332904 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,07319795 0,15318953 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07319795 0,15305026 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,07319795 0,15291125 ! GTP metabolic process GO:0046039 9 9 0,000 0,07319795 0,1527725 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07319795 0,15263399 ! social behavior GO:0035176 14 9 0,000 0,07319795 0,15249573 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07319795 0,15235773 ! artery development GO:0060840 19 9 0,000 0,07319795 0,15221997 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,07319795 0,15208247 ! regulation of glycolysis GO:0006110 15 9 0,000 0,07319795 0,15194521 ! response to pain GO:0048265 16 9 0,000 0,07319795 0,1518082 ! protein complex disassembly GO:0043241 17 9 0,000 0,07319795 0,15167143 GO:0043624|cellular protein complex disassembly, ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,07319795 0,15153492 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07319795 0,15139864 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07319795 0,15126262 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07319795 0,15112683 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07319795 0,15099129 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07319795 0,150856 ! ventral spinal cord development GO:0021517 11 9 0,000 0,07319795 0,15072094 ! protein targeting to ER GO:0045047 19 9 0,000 0,07319795 0,15058613 ! T cell selection GO:0045058 18 9 0,000 0,07319795 0,15045156 ! endoderm development GO:0007492 12 9 0,000 0,07319795 0,15031722 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07319795 0,15018313 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07319795 0,15004928 ! arginine catabolic process GO:0006527 10 9 0,000 0,07319795 0,14991566 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,07319795 0,14978229 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,07319795 0,14964915 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,07319795 0,14951624 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,07319795 0,14938358 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,07319795 0,14925114 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,07319795 0,14911895 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,07319795 0,14898698 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07319795 0,14885525 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07319795 0,14872376 ! mannose metabolic process GO:0006013 9 9 0,000 0,07319795 0,14859249 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,07319795 0,14846146 ! receptor clustering GO:0043113 15 9 0,000 0,07319795 0,14833065 ! epithelial cell development GO:0002064 10 9 0,000 0,07319795 0,14820008 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,07319795 0,14806974 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07319795 0,14793962 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07319795 0,14780974 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07319795 0,14768008 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07319795 0,14755065 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07319795 0,14742145 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,07319795 0,14729247 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07319795 0,14716372 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07319795 0,14703519 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,07319795 0,14690689 ! DNA ligation GO:0006266 14 9 0,000 0,07319795 0,14677881 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,07319795 0,14665095 ! response to amine stimulus GO:0014075 13 9 0,000 0,07319795 0,14652332 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07319795 0,14639591 ! erythrocyte development GO:0048821 11 9 0,000 0,07319795 0,14626872 ! renal water homeostasis GO:0003091 14 9 0,000 0,07319795 0,14614175 ! postreplication repair GO:0006301 11 9 0,000 0,07319795 0,146015 ! mRNA cleavage GO:0006379 13 9 0,000 0,07319795 0,14588847 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07319795 0,14576216 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07319795 0,14563606 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07319795 0,14551019 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07319795 0,14538453 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,07319795 0,14525909 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07319795 0,14513387 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,07319795 0,14500886 ! acid secretion GO:0046717 14 9 0,000 0,07319795 0,14488407 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07319795 0,14475949 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,07319795 0,14463513 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07319795 0,14451098 ! purine base metabolic process GO:0006144 18 9 0,000 0,07319795 0,14438704 ! oocyte differentiation GO:0009994 12 9 0,000 0,07319795 0,14426332 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,07319795 0,1441398 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,07319795 0,1440165 ! spleen development GO:0048536 15 9 0,000 0,07319795 0,14389341 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,07319795 0,14377053 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07319795 0,14364786 ! detection of calcium ion GO:0005513 13 9 0,000 0,07319795 0,1435254 ! blastocyst formation GO:0001825 12 9 0,000 0,07319795 0,14340314 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,07319795 0,1432811 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07319795 0,14315926 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07319795 0,14303763 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07319795 0,14291621 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,07319795 0,14279499 ! prepulse inhibition GO:0060134 14 9 0,000 0,07319795 0,14267398 ! embryonic placenta development GO:0001892 12 9 0,000 0,07319795 0,14255317 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07319795 0,14243256 ! insulin secretion GO:0030073 17 9 0,000 0,07319795 0,14231216 ! sequestering of metal ion GO:0051238 11 9 0,000 0,07319795 0,14219197 ! response to nicotine GO:0035094 16 9 0,000 0,07319795 0,14207198 ! establishment of cell polarity GO:0030010 12 9 0,000 0,07319795 0,14195218 ! nucleus localization GO:0051647 15 9 0,000 0,07319795 0,1418326 ! regulation of synapse organization GO:0050807 12 9 0,000 0,07319795 0,14171321 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,07328048 0,14175367 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,07328048 0,14163455 ! cell projection assembly GO:0030031 76 53 1,000 0,07328048 0,14151563 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,0756926 0,14605116 ! DNA catabolic process GO:0006308 67 54 1,000 0,0756926 0,14592874 ! detection of external stimulus GO:0009581 66 54 1,000 0,0756926 0,14580652 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,0756926 0,1456845 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,0756926 0,14556269 ! exocytosis GO:0006887 74 55 1,000 0,07812978 0,15012406 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,08099512 0,15549981 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,08099512 0,15537012 ! neuron fate specification GO:0048665 11 10 0,000 0,08099512 0,15524065 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,08099512 0,15511139 ! thyroid gland development GO:0030878 19 10 0,000 0,08099512 0,15498234 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,08099512 0,15485351 ! synapsis GO:0007129 13 10 0,000 0,08099512 0,1547249 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,08099512 0,15459649 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,08099512 0,1544683 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,08099512 0,15434033 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,08099512 0,15421256 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,08099512 0,15408501 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,08099512 0,15395767 ! androgen metabolic process GO:0008209 13 10 0,000 0,08099512 0,15383053 ! phospholipid efflux GO:0033700 16 10 0,000 0,08099512 0,15370361 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,08099512 0,1535769 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,08099512 0,15345039 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,08099512 0,15332409 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,08099512 0,15319801 ! pathogenesis GO:0009405 13 10 0,000 0,08099512 0,15307212 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,08099512 0,15294645 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,08099512 0,15282098 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,08099512 0,15269572 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,08099512 0,15257066 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,08099512 0,15244581 ! melanocyte differentiation GO:0030318 15 10 0,000 0,08099512 0,15232116 GO:0050931|pigment cell differentiation, ! polyamine metabolic process GO:0006595 14 10 0,000 0,08099512 0,15219671 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,08099512 0,15207247 ! response to X-ray GO:0010165 16 10 0,000 0,08099512 0,15194843 ! B cell proliferation GO:0042100 14 10 0,000 0,08099512 0,15182459 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,08099512 0,15170096 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,08099512 0,15157752 ! forebrain cell migration GO:0021885 17 10 0,000 0,08099512 0,15145429 ! lipid digestion GO:0044241 15 10 0,000 0,08099512 0,15133126 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,08099512 0,15120842 ! UV protection GO:0009650 14 10 0,000 0,08099512 0,15108579 ! entry into host cell GO:0030260 20 10 0,000 0,08099512 0,15096335 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,08099512 0,15084111 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,08099512 0,15071907 ! negative regulation of ossification GO:0030279 19 10 0,000 0,08099512 0,15059723 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,08099512 0,15047559 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,08099512 0,15035414 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,08099512 0,15023288 ! regulation of organ growth GO:0046620 11 10 0,000 0,08099512 0,15011183 ! response to dsRNA GO:0043331 18 10 0,000 0,08099512 0,14999096 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,08099512 0,14987029 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,08099512 0,14974982 ! embryonic axis specification GO:0000578 12 10 0,000 0,08099512 0,14962954 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,08099512 0,14950945 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,08099512 0,14938956 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,08099512 0,14926985 ! cranial nerve development GO:0021545 12 10 0,000 0,08099512 0,14915034 ! fucose catabolic process GO:0019317 16 10 0,000 0,08099512 0,14903102 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,08099512 0,14891189 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,08099512 0,14879295 ! protein sumoylation GO:0016925 12 10 0,000 0,08099512 0,1486742 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,08099512 0,14855564 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,08099512 0,14843727 ! zymogen activation GO:0031638 14 10 0,000 0,08099512 0,14831909 ! salivary gland development GO:0007431 22 10 0,000 0,08099512 0,14820109 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,08099512 0,14808329 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,08099512 0,14796567 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,08099512 0,14784823 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,08099512 0,14773099 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,08099512 0,14761393 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,08099512 0,14749705 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,08099512 0,14738036 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,08099512 0,14726385 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,08099512 0,14714753 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,08099512 0,14703139 ! detection of bacterium GO:0016045 10 10 0,000 0,08099512 0,14691544 ! embryonic gut development GO:0048566 11 10 0,000 0,08099512 0,14679967 ! activation of innate immune response GO:0002218 10 10 0,000 0,08099512 0,14668408 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,08099512 0,14656867 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,08099512 0,14645344 ! developmental induction GO:0031128 13 10 0,000 0,08099512 0,14633839 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,08099512 0,14622353 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,08099512 0,14610884 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,08099512 0,14599434 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,08099512 0,14588001 ! carbohydrate transport GO:0008643 74 57 1,000 0,083077 0,1495126 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,083077 0,14939571 ! membrane lipid metabolic process GO:0006643 79 57 1,000 0,083077 0,14927899 ! developmental maturation GO:0021700 75 57 1,000 0,083077 0,14916246 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,0855859 0,15354724 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,08811756 0,15796601 ! activation of MAPK activity GO:0000187 84 59 1,000 0,08811756 0,15784298 ! actin filament organization GO:0007015 95 59 1,000 0,08811756 0,15772015 ! rRNA transcription GO:0009303 17 11 0,000 0,08872713 0,15868772 ! respiratory burst GO:0045730 14 11 0,000 0,08872713 0,15856442 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,08872713 0,15844131 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,08872713 0,15831839 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,08872713 0,15819566 ! virus-host interaction GO:0019048 17 11 0,000 0,08872713 0,15807312 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,08872713 0,15795078 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,08872713 0,15782862 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,08872713 0,15770665 ! RNA polyadenylation GO:0043631 19 11 0,000 0,08872713 0,15758487 ! mating GO:0007618 14 11 0,000 0,08872713 0,15746327 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,08872713 0,15734187 ! T cell proliferation GO:0042098 20 11 0,000 0,08872713 0,15722065 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,08872713 0,15709962 ! bone resorption GO:0045453 16 11 0,000 0,08872713 0,15697877 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,08872713 0,15685811 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,08872713 0,15673764 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,08872713 0,15661735 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,08872713 0,15649724 ! syncytium formation GO:0006949 15 11 0,000 0,08872713 0,15637732 ! plasma membrane organization GO:0007009 18 11 0,000 0,08872713 0,15625758 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,08872713 0,15613803 ! focal adhesion formation GO:0048041 24 11 0,000 0,08872713 0,15601866 ! mitotic spindle organization GO:0007052 15 11 0,000 0,08872713 0,15589947 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,08872713 0,15578046 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,08872713 0,15566163 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,08872713 0,15554299 ! adult heart development GO:0007512 11 11 0,000 0,08872713 0,15542453 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,08872713 0,15530624 ! temperature homeostasis GO:0001659 16 11 0,000 0,08872713 0,15518814 ! L-glutamate transport GO:0015813 16 11 0,000 0,08872713 0,15507022 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,08872713 0,15495247 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,08872713 0,1548349 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,08872713 0,15471752 ! stem cell development GO:0048864 29 11 0,000 0,08872713 0,15460031 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,08872713 0,15448327 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,08872713 0,15436642 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,08872713 0,15424974 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,08872713 0,15413324 ! vasoconstriction GO:0042310 15 11 0,000 0,08872713 0,15401691 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,08872713 0,15390076 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,08872713 0,15378478 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,08872713 0,15366898 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,08872713 0,15355335 ! ribosome assembly GO:0042255 13 11 0,000 0,08872713 0,1534379 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,08872713 0,15332262 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,08872713 0,15320751 ! chromatin silencing GO:0006342 19 11 0,000 0,08872713 0,15309258 ! nucleosome positioning GO:0016584 13 11 0,000 0,08872713 0,15297781 ! regulation of isotype switching GO:0045191 19 11 0,000 0,08872713 0,15286322 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,08872713 0,1527488 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,08872713 0,15263456 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,08872713 0,15252048 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,08872713 0,15240657 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,08872713 0,15229284 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,08872713 0,15217927 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,08872713 0,15206587 ! male genitalia development GO:0030539 13 11 0,000 0,08872713 0,15195265 ! cholesterol efflux GO:0033344 19 11 0,000 0,08872713 0,15183959 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,08872713 0,15172669 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,08872713 0,15161397 ! germ cell migration GO:0008354 18 11 0,000 0,08872713 0,15150141 ! defense response to fungus GO:0050832 12 11 0,000 0,08872713 0,15138902 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,08872713 0,1512768 ! lysogeny GO:0030069 18 11 0,000 0,08872713 0,15116474 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,08872713 0,15105285 ! acrosome reaction GO:0007340 13 11 0,000 0,08872713 0,15094113 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,08872713 0,15082957 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,09067144 0,15402092 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,093247 0,15827903 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,093247 0,15816231 ! fatty acid biosynthetic process GO:0006633 92 61 1,000 0,093247 0,15804575 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,093247 0,15792937 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,09584368 0,16220785 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,09584368 0,16208857 ! lactation GO:0007595 20 12 0,000 0,09639453 0,16290038 ! reproductive cellular process GO:0048610 14 12 0,000 0,09639453 0,16278078 ! tRNA modification GO:0006400 14 12 0,000 0,09639453 0,16266135 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,09639453 0,1625421 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,09639453 0,16242302 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,09639453 0,16230411 ! non-recombinational repair GO:0000726 19 12 0,000 0,09639453 0,16218538 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,09639453 0,16206683 ! peroxisomal transport GO:0043574 21 12 0,000 0,09639453 0,16194844 ! cartilage condensation GO:0001502 18 12 0,000 0,09639453 0,16183023 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,09639453 0,16171219 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,09639453 0,16159433 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,09639453 0,16147663 ! heart looping GO:0001947 15 12 0,000 0,09639453 0,16135911 ! palate development GO:0060021 15 12 0,000 0,09639453 0,16124176 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,09639453 0,16112458 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,09639453 0,16100757 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,09639453 0,16089072 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,09639453 0,16077405 ! arginine metabolic process GO:0006525 13 12 0,000 0,09639453 0,16065755 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,09639453 0,16054122 ! methionine metabolic process GO:0006555 13 12 0,000 0,09639453 0,16042505 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,09639453 0,16030905 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,09639453 0,16019322 ! monoamine transport GO:0015844 13 12 0,000 0,09639453 0,16007756 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,09639453 0,15996206 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,09639453 0,15984673 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,09639453 0,15973157 ! L-amino acid transport GO:0015807 20 12 0,000 0,09639453 0,15961657 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,09639453 0,15950174 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,09639453 0,15938707 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,09639453 0,15927257 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,09639453 0,15915823 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,09639453 0,15904406 ! cerebellum development GO:0021549 13 12 0,000 0,09639453 0,15893005 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,09639453 0,1588162 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,09639453 0,15870252 ! histone methylation GO:0016571 15 12 0,000 0,09639453 0,158589 ! autonomic nervous system development GO:0048483 23 12 0,000 0,09639453 0,15847564 ! gland morphogenesis GO:0022612 23 12 0,000 0,09639453 0,15836244 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,09639453 0,15824941 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,09639453 0,15813653 ! regulation of epidermis development GO:0045682 17 12 0,000 0,09639453 0,15802382 ! intestinal absorption GO:0050892 19 12 0,000 0,09639453 0,15791127 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,09639453 0,15779887 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,09639453 0,15768664 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,09639453 0,15757457 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,09639453 0,15746266 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,09639453 0,1573509 ! microspike assembly GO:0030035 23 12 0,000 0,09639453 0,1572393 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,09639453 0,15712787 ! response to cold GO:0009409 14 12 0,000 0,09639453 0,15701659 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,09846096 0,16026908 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,09846096 0,16015574 ! regulation of lipase activity GO:0060191 109 63 1,000 0,09846096 0,16004255 ! adaptive immune response GO:0002250 94 64 1,000 0,10109832 0,16421338 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 1,000 0,10375524 0,16841006 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,10375524 0,16829129 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,10375524 0,16817269 ! defense response to bacterium GO:0042742 73 65 1,000 0,10375524 0,16805426 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,10399785 0,16832868 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,10399785 0,16821031 ! cGMP metabolic process GO:0046068 16 13 0,000 0,10399785 0,1680921 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,10399785 0,16797406 ! water transport GO:0006833 17 13 0,000 0,10399785 0,16785618 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,10399785 0,16773847 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,10399785 0,16762092 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,10399785 0,16750354 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,10399785 0,16738632 ! organelle fusion GO:0048284 28 13 0,000 0,10399785 0,16726927 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,10399785 0,16715238 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,10399785 0,16703565 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,10399785 0,16691909 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,10399785 0,16680269 ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,10399785 0,16668645 ! glutamate metabolic process GO:0006536 18 13 0,000 0,10399785 0,16657037 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,10399785 0,16645446 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,10399785 0,1663387 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,10399785 0,16622311 ! NAD metabolic process GO:0019674 21 13 0,000 0,10399785 0,16610768 ! exocrine system development GO:0035272 27 13 0,000 0,10399785 0,1659924 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,10399785 0,16587729 ! bone mineralization GO:0030282 15 13 0,000 0,10399785 0,16576234 ! regulation of exocytosis GO:0017157 17 13 0,000 0,10399785 0,16564755 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,10399785 0,16553291 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,10399785 0,16541843 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,10399785 0,16530412 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,10399785 0,16518996 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,10399785 0,16507595 ! genitalia development GO:0048806 15 13 0,000 0,10399785 0,16496211 ! regulation of cellular pH GO:0030641 20 13 0,000 0,10399785 0,16484842 ! cellular pigmentation GO:0033059 24 13 0,000 0,10399785 0,16473489 ! tissue regeneration GO:0042246 21 13 0,000 0,10399785 0,16462151 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,10399785 0,16450829 ! cofactor transport GO:0051181 19 13 0,000 0,10399785 0,16439523 ! NADP metabolic process GO:0006739 18 13 0,000 0,10399785 0,16428232 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,10399785 0,16416956 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,10399785 0,16405697 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,10399785 0,16394452 ! gas transport GO:0015669 18 13 0,000 0,10399785 0,16383223 ! heme biosynthetic process GO:0006783 20 13 0,000 0,10399785 0,16372009 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,10399785 0,16360811 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,10399785 0,16349628 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,10399785 0,1633846 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,10399785 0,16327308 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,10643121 0,16697939 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,10912572 0,17109009 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,11153762 0,17475241 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,11153762 0,17463345 ! superoxide anion generation GO:0042554 18 14 0,000 0,11153762 0,17451465 ! neuron maturation GO:0042551 21 14 0,000 0,11153762 0,17439601 ! regulation of S phase GO:0033261 18 14 0,000 0,11153762 0,17427754 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,11153762 0,17415922 ! myotube differentiation GO:0014902 21 14 0,000 0,11153762 0,17404107 ! inositol metabolic process GO:0006020 20 14 0,000 0,11153762 0,17392308 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,11153762 0,17380524 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,11153762 0,17368757 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,11153762 0,17357005 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,11153762 0,1734527 ! gene silencing by RNA GO:0031047 20 14 0,000 0,11153762 0,1733355 ! response to cAMP GO:0051591 19 14 0,000 0,11153762 0,17321846 ! startle response GO:0001964 21 14 0,000 0,11153762 0,17310158 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,11153762 0,17298485 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,11153762 0,17286829 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,11153762 0,17275188 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,11153762 0,17263562 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,11153762 0,17251953 ! glycine metabolic process GO:0006544 22 14 0,000 0,11153762 0,17240359 ! pituitary gland development GO:0021983 23 14 0,000 0,11153762 0,1722878 ! cellular response to starvation GO:0009267 21 14 0,000 0,11153762 0,17217217 ! lysosomal transport GO:0007041 20 14 0,000 0,11153762 0,1720567 ! regulation of heart rate GO:0002027 23 14 0,000 0,11153762 0,17194138 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,11153762 0,17182621 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,11153762 0,1717112 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,11153762 0,17159635 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,11153762 0,17148164 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,11153762 0,17136709 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,11153762 0,17125269 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,11153762 0,17113845 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,11153762 0,17102436 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,11153762 0,17091042 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,11153762 0,17079663 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,11153762 0,17068299 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,11153762 0,17056951 ! mRNA splice site selection GO:0006376 26 14 0,000 0,11153762 0,17045617 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,11153762 0,17034299 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,11153762 0,17022995 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,11153762 0,17011707 ! water homeostasis GO:0030104 24 14 0,000 0,11153762 0,17000433 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,11153762 0,16989175 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,11153762 0,16977931 ! muscle maintenance GO:0046716 19 14 0,000 0,11153762 0,16966702 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,11153762 0,16955488 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,11153762 0,16944289 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,11153762 0,16933105 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,11153762 0,16921935 ! cilium assembly GO:0042384 20 14 0,000 0,11153762 0,1691078 ! peptide hormone secretion GO:0030072 23 14 0,000 0,11153762 0,1689964 ! acute inflammatory response GO:0002526 92 68 1,000 0,11183829 0,1693404 ! learning or memory GO:0007611 123 68 1,000 0,11183829 0,16922899 ! inorganic anion transport GO:0015698 93 68 1,000 0,11183829 0,16911773 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,11456842 0,1731323 ! response to metal ion GO:0010038 103 70 1,000 0,11731563 0,17716739 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,11731563 0,17705114 ! humoral immune response GO:0006959 86 70 1,000 0,11731563 0,17693504 ! regulation of catabolic process GO:0009894 106 70 1,000 0,11731563 0,1768191 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,11901438 0,179262 ! positive regulation of cell size GO:0045793 20 15 0,000 0,11901438 0,17914468 ! metencephalon development GO:0022037 19 15 0,000 0,11901438 0,17902752 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,11901438 0,17891051 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,11901438 0,17879365 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,11901438 0,17867694 ! skin development GO:0043588 25 15 0,000 0,11901438 0,17856039 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,11901438 0,17844399 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,11901438 0,17832774 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,11901438 0,17821164 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,11901438 0,17809569 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,11901438 0,17797989 ! bile acid metabolic process GO:0008206 22 15 0,000 0,11901438 0,17786425 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,11901438 0,17774875 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,11901438 0,1776334 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,11901438 0,17751821 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,11901438 0,17740316 ! myoblast differentiation GO:0045445 27 15 0,000 0,11901438 0,17728826 ! centrosome cycle GO:0007098 16 15 0,000 0,11901438 0,17717351 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,11901438 0,17705891 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,11901438 0,17694446 ! cerebral cortex development GO:0021987 29 15 0,000 0,11901438 0,17683015 ! response to osmotic stress GO:0006970 22 15 0,000 0,11901438 0,17671599 ! vesicle coating GO:0006901 25 15 0,000 0,11901438 0,17660198 ! DNA integration GO:0015074 22 15 0,000 0,11901438 0,17648812 ! peptide secretion GO:0002790 27 15 0,000 0,11901438 0,1763744 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,11901438 0,17626083 ! regulation of vasodilation GO:0042312 24 15 0,000 0,11901438 0,17614741 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,11901438 0,17603413 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,11901438 0,175921 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,11901438 0,17580801 ! biomineral formation GO:0031214 18 15 0,000 0,11901438 0,17569517 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,11901438 0,17558247 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,11901438 0,17546992 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,11901438 0,17535751 ! dopamine metabolic process GO:0042417 30 15 0,000 0,11901438 0,17524525 ! organic cation transport GO:0015695 19 15 0,000 0,11901438 0,17513313 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,11901438 0,17502115 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,11901438 0,17490931 ! defense response to virus GO:0051607 27 15 0,000 0,11901438 0,17479762 ! peptide hormone processing GO:0016486 19 15 0,000 0,11901438 0,17468607 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,12007944 0,17613693 ! muscle cell differentiation GO:0042692 104 71 1,000 0,12007944 0,17602467 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,12007944 0,17591256 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,12007944 0,17580058 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,12285939 0,17975611 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,12285939 0,17964183 ! regulation of blood pressure GO:0008217 107 73 1,000 0,12565502 0,1836128 ! tube morphogenesis GO:0035239 118 73 1,000 0,12565502 0,18349622 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,12565502 0,18337978 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,12565502 0,1832635 ! protein secretion GO:0009306 27 16 0,000 0,12642864 0,18427495 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,12642864 0,18415825 ! hormone secretion GO:0046879 25 16 0,000 0,12642864 0,18404169 ! bone remodeling GO:0046849 24 16 0,000 0,12642864 0,18392528 ! endothelial cell migration GO:0043542 22 16 0,000 0,12642864 0,18380902 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,12642864 0,18369291 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,12642864 0,18357694 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,12642864 0,18346112 ! glial cell development GO:0021782 24 16 0,000 0,12642864 0,18334544 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,12642864 0,18322991 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,12642864 0,18311453 ! protein polyubiquitination GO:0000209 26 16 0,000 0,12642864 0,18299929 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,12642864 0,1828842 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,12642864 0,18276925 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,12642864 0,18265444 ! regulation of protein binding GO:0043393 27 16 0,000 0,12642864 0,18253978 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,12642864 0,18242527 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,12642864 0,18231089 ! protein export from nucleus GO:0006611 24 16 0,000 0,12642864 0,18219666 ! negative regulation of immune response GO:0050777 28 16 0,000 0,12642864 0,18208258 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,12642864 0,18196863 ! DNA replication initiation GO:0006270 25 16 0,000 0,12642864 0,18185483 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,12642864 0,18174117 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,12642864 0,18162765 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,12642864 0,18151428 ! diencephalon development GO:0021536 25 16 0,000 0,12642864 0,18140104 ! oogenesis GO:0048477 23 16 0,000 0,12642864 0,18128795 ! neural crest cell migration GO:0001755 24 16 0,000 0,12642864 0,181175 ! G1 phase GO:0051318 27 16 0,000 0,12642864 0,18106219 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,12642864 0,18094952 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,12642864 0,18083699 ! steroid catabolic process GO:0006706 22 16 0,000 0,12642864 0,18072459 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,12642864 0,18061234 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,12642864 0,18050023 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,12642864 0,18038826 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,12642864 0,18027642 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,12642864 0,18016473 ! sperm-egg recognition GO:0035036 16 16 0,000 0,12642864 0,18005317 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,12642864 0,17994175 ! nerve development GO:0021675 18 16 0,000 0,12642864 0,17983047 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,12642864 0,17971933 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,12642864 0,17960832 ! protein import into nucleus GO:0006606 118 74 1,000 0,12846586 0,18238981 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,12846586 0,18227729 ! response to inorganic substance GO:0010035 115 75 1,000 0,13129148 0,18617164 ! negative regulation of growth GO:0045926 123 75 1,000 0,13129148 0,18605694 ! regulation of ligase activity GO:0051340 114 75 1,000 0,13129148 0,18594237 ! nuclear import GO:0051170 121 75 1,000 0,13129148 0,18582794 ! cofactor biosynthetic process GO:0051188 92 75 1,000 0,13129148 0,18571366 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,13378092 0,1891187 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,13378092 0,18900253 ! negative regulation of defense response GO:0031348 19 17 0,000 0,13378092 0,18888651 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,13378092 0,18877063 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,13378092 0,18865489 ! glycerol metabolic process GO:0006071 20 17 0,000 0,13378092 0,18853929 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,13378092 0,18842384 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,13378092 0,18830852 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,13378092 0,18819335 ! signal complex assembly GO:0007172 29 17 0,000 0,13378092 0,18807832 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,13378092 0,18796342 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,13378092 0,18784867 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,13378092 0,18773406 ! keratinization GO:0031424 17 17 0,000 0,13378092 0,18761959 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,13378092 0,18750526 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,13378092 0,18739106 ! retinoid metabolic process GO:0001523 22 17 0,000 0,13378092 0,18727701 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,13378092 0,18716309 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,13378092 0,18704932 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,13378092 0,18693568 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,13378092 0,18682218 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,13378092 0,18670881 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,13378092 0,18659559 ! membrane budding GO:0006900 29 17 0,000 0,13378092 0,1864825 ! heme metabolic process GO:0042168 27 17 0,000 0,13378092 0,18636955 ! actin filament bundle formation GO:0051017 26 17 0,000 0,13378092 0,18625673 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,13378092 0,18614406 ! body fluid secretion GO:0007589 27 17 0,000 0,13378092 0,18603152 ! stem cell differentiation GO:0048863 36 17 0,000 0,13378092 0,18591911 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,13378092 0,18580684 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,13378092 0,1856947 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,13378092 0,18558271 ! sensory perception of pain GO:0019233 23 17 0,000 0,13378092 0,18547084 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,13378092 0,18535911 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,13378092 0,18524752 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,13378092 0,18513606 ! synaptogenesis GO:0007416 24 17 0,000 0,13378092 0,18502473 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,13378092 0,18491354 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,13378092 0,18480248 ! cell-cell junction organization GO:0045216 25 17 0,000 0,13378092 0,18469155 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,13378092 0,18458076 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,13378092 0,1844701 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,13378092 0,18435957 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,13378092 0,18424918 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,13378092 0,18413891 ! tRNA metabolic process GO:0006399 95 76 1,000 0,13413143 0,18451093 ! regulation of protein transport GO:0051223 114 76 1,000 0,13413143 0,18440065 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 1,000 0,13698527 0,18821154 ! gland development GO:0048732 148 77 1,000 0,13698527 0,18809917 ! protein ubiquitination GO:0016567 125 77 1,000 0,13698527 0,18798694 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,14107175 0,19347944 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,14107175 0,19336413 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,14107175 0,19324897 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,14107175 0,19313394 ! cAMP metabolic process GO:0046058 33 18 0,000 0,14107175 0,19301905 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,14107175 0,19290429 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,14107175 0,19278967 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,14107175 0,19267519 ! axis specification GO:0009798 26 18 0,000 0,14107175 0,19256084 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,14107175 0,19244663 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,14107175 0,19233255 ! pancreas development GO:0031016 26 18 0,000 0,14107175 0,19221861 ! glutamine metabolic process GO:0006541 23 18 0,000 0,14107175 0,19210481 ! response to retinoic acid GO:0032526 25 18 0,000 0,14107175 0,19199113 ! pigmentation during development GO:0048066 31 18 0,000 0,14107175 0,1918776 ! central nervous system neuron development GO:0021954 30 18 0,000 0,14107175 0,19176419 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,14107175 0,19165093 ! fucose metabolic process GO:0006004 26 18 0,000 0,14107175 0,19153779 ! response to fungus GO:0009620 19 18 0,000 0,14107175 0,19142479 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,14107175 0,19131192 ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,14107175 0,19119918 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,14107175 0,19108658 ! visual learning GO:0008542 35 18 0,000 0,14107175 0,19097411 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,14107175 0,19086177 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,14107175 0,19074957 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,14107175 0,19063749 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,14107175 0,19052555 ! vitamin transport GO:0051180 24 18 0,000 0,14107175 0,19041374 ! hormone transport GO:0009914 27 18 0,000 0,14107175 0,19030206 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,14107175 0,19019051 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,14107175 0,1900791 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,14107175 0,18996781 ! cell-cell recognition GO:0009988 20 18 0,000 0,14107175 0,18985665 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,14107175 0,18974562 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,14107175 0,18963473 ! gut development GO:0048565 26 18 0,000 0,14107175 0,18952396 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,14107175 0,18941332 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,14107175 0,18930281 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,14562587 0,1953 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 1,000 0,14562587 0,19518618 ! forebrain development GO:0030900 131 80 1,000 0,14562587 0,19507251 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,14830162 0,19854116 ! positive regulation of ossification GO:0045778 30 19 0,000 0,14830162 0,19842566 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,14830162 0,1983103 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,14830162 0,19819507 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,14830162 0,19807998 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,14830162 0,19796501 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,14830162 0,19785018 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,14830162 0,19773549 ! regeneration GO:0031099 32 19 0,000 0,14830162 0,19762093 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,14830162 0,1975065 ! sensory perception of taste GO:0050909 23 19 0,000 0,14830162 0,1973922 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,14830162 0,19727803 ! smooth muscle contraction GO:0006939 36 19 0,000 0,14830162 0,197164 ! peroxisome organization GO:0007031 29 19 0,000 0,14830162 0,1970501 ! digestive system process GO:0022600 30 19 0,000 0,14830162 0,19693633 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,14830162 0,19682269 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,14830162 0,19670918 ! response to vitamin A GO:0033189 26 19 0,000 0,14830162 0,1965958 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,14830162 0,19648256 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,14830162 0,19636944 ! response to starvation GO:0042594 30 19 0,000 0,14830162 0,19625645 ! sex determination GO:0007530 29 19 0,000 0,14830162 0,1961436 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,14830162 0,19603087 ! plasma membrane fusion GO:0045026 23 19 0,000 0,14830162 0,19591828 ! cytolysis GO:0019835 20 19 0,000 0,14830162 0,19580581 ! renal system process GO:0003014 35 19 0,000 0,14830162 0,19569347 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,14830162 0,19558126 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,14830162 0,19546918 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,14830162 0,19535723 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,14830162 0,1952454 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,14830162 0,19513371 ! sarcomere organization GO:0045214 23 19 0,000 0,14830162 0,19502214 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,14830162 0,1949107 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,14830162 0,19479938 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,14830162 0,1946882 ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,14830162 0,19457714 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,14830162 0,1944662 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,14830162 0,19435539 ! protein stabilization GO:0050821 26 19 0,000 0,14830162 0,19424471 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,15547104 0,20351929 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,15547104 0,20340352 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,15547104 0,20328789 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,15547104 0,20317238 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,15547104 0,20305701 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,15547104 0,20294177 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,15547104 0,20282666 ! spinal cord development GO:0021510 31 20 0,000 0,15547104 0,20271167 ! response to ethanol GO:0045471 37 20 0,000 0,15547104 0,20259682 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,15547104 0,2024821 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,15547104 0,20236751 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,15547104 0,20225305 ! chromosome condensation GO:0030261 31 20 0,000 0,15547104 0,20213872 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,15547104 0,20202452 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,15547104 0,20191044 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,15547104 0,2017965 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,15547104 0,20168268 ! DNA modification GO:0006304 28 20 0,000 0,15547104 0,20156899 ! collagen fibril organization GO:0030199 45 20 0,000 0,15547104 0,20145543 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,15547104 0,201342 ! collagen catabolic process GO:0030574 25 20 0,000 0,15547104 0,2012287 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,15547104 0,20111552 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,15547104 0,20100247 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,15547104 0,20088955 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,16026578 0,20696873 ! Golgi vesicle transport GO:0048193 138 85 1,000 0,16026578 0,20685258 ! rRNA metabolic process GO:0016072 107 85 1,000 0,16026578 0,20673657 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 1,000 0,16026578 0,20662069 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,16026578 0,20650493 ! regulation of protein localization GO:0032880 132 85 1,000 0,16026578 0,20638931 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,16258052 0,20925305 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,16258052 0,20913602 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,16258052 0,20901912 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,16258052 0,20890235 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,16258052 0,20878571 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,16258052 0,2086692 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,16258052 0,20855282 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,16258052 0,20843657 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,16258052 0,20832045 ! vesicle docking GO:0048278 27 21 0,000 0,16258052 0,20820445 ! phototransduction GO:0007602 25 21 0,000 0,16258052 0,20808859 ! visual behavior GO:0007632 39 21 0,000 0,16258052 0,20797286 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,16258052 0,20785725 ! ovarian follicle development GO:0001541 30 21 0,000 0,16258052 0,20774178 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,16258052 0,20762643 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,16258052 0,20751121 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,16258052 0,20739612 ! cell aging GO:0007569 32 21 0,000 0,16258052 0,20728115 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,16258052 0,20716632 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,16258052 0,20705161 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,16258052 0,20693702 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,16258052 0,20682257 ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,16258052 0,20670824 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,16258052 0,20659403 ! fatty acid transport GO:0015908 30 21 0,000 0,16258052 0,20647996 ! immunoglobulin production GO:0002377 33 21 0,000 0,16258052 0,206366 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,16258052 0,20625218 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,16258052 0,20613848 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,16258052 0,2060249 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,16258052 0,20591145 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,16258052 0,20579813 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,16258052 0,20568493 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,16258052 0,20557185 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,16258052 0,2054589 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,16258052 0,20534607 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,16258052 0,20523337 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,16258052 0,20512079 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,16258052 0,20500833 ! protein processing GO:0016485 114 88 1,000 0,16917574 0,21320778 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,16963056 0,2136639 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,16963056 0,21354695 ! viral genome replication GO:0019079 29 22 0,000 0,16963056 0,21343013 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,16963056 0,21331344 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,16963056 0,21319688 ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,16963056 0,21308044 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,16963056 0,21296413 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,16963056 0,21284794 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,16963056 0,21273189 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,16963056 0,21261596 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,16963056 0,21250015 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,16963056 0,21238448 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,16963056 0,21226892 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,16963056 0,2121535 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,16963056 0,2120382 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,16963056 0,21192302 ! membrane depolarization GO:0051899 35 22 0,000 0,16963056 0,21180797 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,16963056 0,21169304 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,16963056 0,21157824 ! blastocyst development GO:0001824 37 22 0,000 0,16963056 0,21146357 ! neural tube closure GO:0001843 33 22 0,000 0,16963056 0,21134901 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,16963056 0,21123459 ! protein tetramerization GO:0051262 39 22 0,000 0,16963056 0,21112028 ! regulation of T cell activation GO:0050863 128 89 1,000 0,17216446 0,21415807 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,17516195 0,21776891 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,17662164 0,21946503 ! neuron fate commitment GO:0048663 32 23 0,000 0,17662164 0,21934653 ! embryonic pattern specification GO:0009880 31 23 0,000 0,17662164 0,21922816 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,17662164 0,21910991 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,17662164 0,21899179 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,17662164 0,2188738 ! vesicle targeting GO:0006903 32 23 0,000 0,17662164 0,21875594 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,17662164 0,2186382 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,17662164 0,21852059 ! osteoblast differentiation GO:0001649 40 23 0,000 0,17662164 0,2184031 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,17662164 0,21828575 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,17662164 0,21816851 ! interaction with host GO:0051701 37 23 0,000 0,17662164 0,21805141 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,17662164 0,21793443 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,17662164 0,21781757 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,17662164 0,21770084 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,17662164 0,21758424 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! cell fate determination GO:0001709 45 23 0,000 0,17662164 0,21746776 ! pentose metabolic process GO:0019321 31 23 0,000 0,17662164 0,2173514 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,17662164 0,21723517 ! spermatid development GO:0007286 33 23 0,000 0,17662164 0,21711907 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,17662164 0,21700308 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,17662164 0,21688722 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,17662164 0,21677149 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,17662164 0,21665588 ! telomere organization GO:0032200 32 23 0,000 0,17662164 0,21654039 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,17662164 0,21642503 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,17662164 0,21630978 ! regulation of amine transport GO:0051952 38 23 0,000 0,17662164 0,21619466 ! liver development GO:0001889 40 23 0,000 0,17662164 0,21607967 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,1811818 0,22154075 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,18355426 0,22432242 ! initiation of viral infection GO:0019059 42 24 0,000 0,18355426 0,22420329 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,18355426 0,22408429 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,18355426 0,22396541 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,18355426 0,22384666 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,18355426 0,22372803 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,18355426 0,22360953 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,18355426 0,22349116 ! receptor metabolic process GO:0043112 37 24 0,000 0,18355426 0,22337291 ! neural crest cell development GO:0014032 39 24 0,000 0,18355426 0,22325479 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,18355426 0,22313679 ! primary neural tube formation GO:0014020 35 24 0,000 0,18355426 0,22301891 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,18355426 0,22290116 ! base-excision repair GO:0006284 31 24 0,000 0,18355426 0,22278354 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,18355426 0,22266603 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,18355426 0,22254866 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,18355426 0,2224314 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,18355426 0,22231427 ! response to oxidative stress GO:0006979 141 94 1,000 0,18723251 0,22664988 ! regulation of binding GO:0051098 151 95 1,000 0,19026859 0,23020398 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,1904289 0,2302768 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,1904289 0,2301558 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,1904289 0,23003492 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,1904289 0,22991416 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,1904289 0,22979354 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,1904289 0,22967304 ! peptide transport GO:0015833 43 25 0,000 0,1904289 0,22955266 ! male gonad development GO:0008584 33 25 0,000 0,1904289 0,22943241 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,1904289 0,22931229 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,1904289 0,2291923 ! phospholipid transport GO:0015914 35 25 0,000 0,1904289 0,22907243 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,1904289 0,22895268 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,1904289 0,22883306 ! detection of light stimulus GO:0009583 30 25 0,000 0,1904289 0,22871357 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,1904289 0,2285942 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,1904289 0,22847495 ! leukocyte proliferation GO:0070661 39 25 0,000 0,1904289 0,22835583 GO:0032943|mononuclear cell proliferation, ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,19331138 0,2316916 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,19331138 0,23157092 ! protein maturation GO:0051604 129 96 1,000 0,19331138 0,23145038 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,19636056 0,23497881 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,19724605 0,23591571 ! translational initiation GO:0006413 43 26 0,000 0,19724605 0,2357931 ! regulation of pH GO:0006885 36 26 0,000 0,19724605 0,23567061 ! circadian rhythm GO:0007623 42 26 0,000 0,19724605 0,23554824 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,19724605 0,23542601 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,19724605 0,2353039 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,19724605 0,23518192 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,19724605 0,23506006 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,19724605 0,23493833 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,19724605 0,23481673 ! extracellular structure organization GO:0043062 156 99 1,000 0,20247679 0,2409191 ! protein import GO:0017038 156 99 1,000 0,20247679 0,24079453 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,20400618 0,24248797 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,20400618 0,24236272 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,20400618 0,24223759 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,20400618 0,2421126 ! membrane docking GO:0022406 39 27 0,000 0,20400618 0,24198774 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,20400618 0,241863 ! catechol metabolic process GO:0009712 43 27 0,000 0,20400618 0,24173839 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,20400618 0,24161391 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,20400618 0,24148956 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,20400618 0,24136534 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,20400618 0,24124124 ! natural killer cell activation GO:0030101 35 27 0,000 0,20400618 0,24111728 ! lipid oxidation GO:0034440 38 27 0,000 0,20400618 0,24099344 GO:0019395|fatty acid oxidation, ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,20400618 0,24086972 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,20400618 0,24074614 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 0,000 0,20400618 0,24062268 ! gene silencing GO:0016458 41 27 0,000 0,20400618 0,24049934 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,20554322 0,2421872 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,21070977 0,2481477 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,21070977 0,24802071 ! phenol metabolic process GO:0018958 44 28 0,000 0,21070977 0,24789384 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,21070977 0,24776711 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,21070977 0,2476405 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,21070977 0,24751403 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,21070977 0,24738768 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,21070977 0,24726146 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,21070977 0,24713537 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,21070977 0,24700941 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,21070977 0,24688358 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,21070977 0,24675787 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,21070977 0,2466323 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,21070977 0,24650685 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,21070977 0,24638153 ! mesoderm formation GO:0001707 46 28 0,000 0,21070977 0,24625633 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,21070977 0,24613127 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,21070977 0,24600633 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,21070977 0,24588151 ! neural tube formation GO:0001841 41 28 0,000 0,21070977 0,24575683 ! regulation of innate immune response GO:0045088 38 29 0,000 0,21735728 0,25338152 ! ovulation cycle process GO:0022602 41 29 0,000 0,21735728 0,25325316 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,21735728 0,25312493 ! protein targeting to membrane GO:0006612 53 29 0,000 0,21735728 0,25299683 ! mismatch repair GO:0006298 34 29 0,000 0,21735728 0,25286886 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,21735728 0,25274102 ! formation of primary germ layer GO:0001704 48 29 0,000 0,21735728 0,25261331 ! eye morphogenesis GO:0048592 51 29 0,000 0,21735728 0,25248573 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,21735728 0,25235827 ! tissue homeostasis GO:0001894 42 29 0,000 0,21735728 0,25223095 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,22394918 0,25974943 ! collagen metabolic process GO:0032963 40 30 0,000 0,22394918 0,25961851 ! organic anion transport GO:0015711 51 30 0,000 0,22394918 0,25948772 ! cholesterol transport GO:0030301 46 30 0,000 0,22394918 0,25935706 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,22394918 0,25922653 ! spliceosome assembly GO:0000245 49 30 0,000 0,22394918 0,25909614 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,22394918 0,25896587 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,22394918 0,25883574 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,22394918 0,25870574 ! ovulation cycle GO:0042698 43 30 0,000 0,22394918 0,25857586 ! hindbrain development GO:0030902 45 30 0,000 0,22394918 0,25844612 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,22394918 0,25831651 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,22394918 0,25818703 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,22394918 0,25805767 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,22394918 0,25792845 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,23048594 0,26532415 ! negative regulation of secretion GO:0051048 49 31 0,000 0,23048594 0,26519142 ! glial cell differentiation GO:0010001 55 31 0,000 0,23048594 0,26505883 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,23048594 0,26492637 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,23048594 0,26479403 ! odontogenesis GO:0042476 50 31 0,000 0,23048594 0,26466184 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,23048594 0,26452977 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,23048594 0,26439783 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,23048594 0,26426603 ! metanephros development GO:0001656 58 31 0,000 0,23048594 0,26413436 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,23048594 0,26400282 ! cell fate specification GO:0001708 37 31 0,000 0,23048594 0,26387141 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,23048594 0,26374013 ! regulation of muscle development GO:0048634 48 32 0,000 0,23696801 0,27102258 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,23696801 0,27088788 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,23696801 0,27075331 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,23696801 0,27061887 ! meiosis I GO:0007127 52 32 0,000 0,23696801 0,27048457 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,23696801 0,2703504 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,23696801 0,27021637 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,23696801 0,27008246 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,23696801 0,26994869 ! regulation of protein stability GO:0031647 48 32 0,000 0,23696801 0,26981506 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,23696801 0,26968155 ! cytokine production GO:0001816 44 32 0,000 0,23696801 0,26954818 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,23696801 0,26941494 ! vesicle localization GO:0051648 47 32 0,000 0,23696801 0,26928183 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,24339584 0,2764496 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,24339584 0,27631315 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,24339584 0,27617683 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,24339584 0,27604065 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,24339584 0,2759046 ! sister chromatid segregation GO:0000819 46 33 0,000 0,24339584 0,27576869 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,24339584 0,27563291 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,24339584 0,27549726 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,24339584 0,27536175 ! female gonad development GO:0008585 49 33 0,000 0,24339584 0,27522637 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,24339584 0,27509112 ! positive regulation of cell development GO:0010720 54 33 0,000 0,24339584 0,27495601 ! lipid homeostasis GO:0055088 55 33 0,000 0,24339584 0,27482103 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,24339584 0,27468618 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,24339584 0,27455146 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,24339584 0,27441688 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,24339584 0,27428243 ! mRNA catabolic process GO:0006402 48 34 0,000 0,24976989 0,2813275 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,24976989 0,28118979 ! feeding behavior GO:0007631 45 34 0,000 0,24976989 0,28105223 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,24976989 0,28091479 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,24976989 0,28077749 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,24976989 0,28064033 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,24976989 0,2805033 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,24976989 0,2803664 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,24976989 0,28022963 ! female gamete generation GO:0007292 43 34 0,000 0,24976989 0,280093 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,24976989 0,27995651 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,24976989 0,27982014 ! embryonic organ development GO:0048568 45 34 0,000 0,24976989 0,27968391 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,25609061 0,28662209 ! Notch signaling pathway GO:0007219 56 35 0,000 0,25609061 0,28648268 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,25609061 0,28634341 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,25609061 0,28620427 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,25609061 0,28606527 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,25609061 0,2859264 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,25609061 0,28578767 ! pigment metabolic process GO:0042440 61 35 0,000 0,25609061 0,28564907 ! protein homooligomerization GO:0051260 52 35 0,000 0,25609061 0,28551061 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,26235843 0,29235677 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,26235843 0,2922152 ! negative regulation of binding GO:0051100 58 36 0,000 0,26235843 0,29207376 ! organic ether metabolic process GO:0018904 46 36 0,000 0,26235843 0,29193245 ! neural tube development GO:0021915 50 36 0,000 0,26235843 0,29179129 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,26235843 0,29165026 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,26235843 0,29150936 GO:0046660|female sex differentiation, ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,26235843 0,29136861 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,26857379 0,29812728 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,26857379 0,29798347 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,26857379 0,29783979 ! learning GO:0007612 67 37 0,000 0,26857379 0,29769625 ! ion transmembrane transport GO:0034220 56 37 0,000 0,26857379 0,29755286 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,26857379 0,29740959 ! regulation of protein secretion GO:0050708 51 37 0,000 0,26857379 0,29726647 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,26857379 0,29712349 ! gliogenesis GO:0042063 71 38 0,000 0,27473715 0,30379588 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,27473715 0,3036499 ! maintenance of location in cell GO:0051651 69 38 0,000 0,27473715 0,30350405 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,28084891 0,31010681 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,28084891 0,30995801 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,28084891 0,30980935 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,28084891 0,30966083 ! male sex differentiation GO:0046661 53 39 0,000 0,28084891 0,30951246 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,28084891 0,30936422 ! chromatin remodeling GO:0006338 68 39 0,000 0,28084891 0,30921613 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,28084891 0,30906818 ! JNK cascade GO:0007254 54 39 0,000 0,28084891 0,30892037 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,28690952 0,3154359 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,28690952 0,31528519 ! inner ear development GO:0048839 57 40 0,000 0,28690952 0,31513462 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,28690952 0,3149842 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,28690952 0,31483392 ! B cell differentiation GO:0030183 62 40 0,000 0,28690952 0,31468379 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,28690952 0,31453379 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,28690952 0,31438394 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,2929194 0,32081648 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,2929194 0,32066379 ! endosome transport GO:0016197 71 41 0,000 0,2929194 0,32051124 ! striated muscle contraction GO:0006941 62 41 0,000 0,2929194 0,32035883 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,2929194 0,32020657 ! biopolymer methylation GO:0043414 62 41 0,000 0,2929194 0,32005445 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,2929194 0,31990248 ! mitochondrial transport GO:0006839 60 42 0,000 0,29887897 0,32625611 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,29887897 0,32610134 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,29887897 0,32594672 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,29887897 0,32579224 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,29887897 0,32563791 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,29887897 0,32548373 ! excretion GO:0007588 63 42 0,000 0,29887897 0,32532969 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,29887897 0,32517579 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,30478865 0,33144865 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,30478865 0,33129201 ! tRNA processing GO:0008033 49 43 0,000 0,30478865 0,33113552 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,30478865 0,33097917 ! vesicle organization GO:0016050 79 43 0,000 0,30478865 0,33082298 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,30478865 0,33066693 ! methylation GO:0032259 64 43 0,000 0,30478865 0,33051103 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,31064885 0,33670705 ! glycolysis GO:0006096 53 44 0,000 0,31064885 0,33654845 ! regulation of ion transport GO:0043269 57 44 0,000 0,31064885 0,33639 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,31064885 0,3362317 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,31064885 0,33607354 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,31064885 0,33591554 ! RNA catabolic process GO:0006401 64 45 0,000 0,31645999 0,34203852 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,31645999 0,34187786 ! cell maturation GO:0048469 60 45 0,000 0,31645999 0,34171736 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,32222247 0,34777648 ! regulation of ossification GO:0030278 71 46 0,000 0,32222247 0,34761336 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,32222247 0,34745039 ! viral infectious cycle GO:0019058 71 47 0,000 0,3279367 0,3534463 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,3279367 0,35328075 ! endocrine system development GO:0035270 83 47 0,000 0,3279367 0,35311536 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,3279367 0,35295012 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,3279367 0,35278503 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,3279367 0,3526201 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,3279367 0,35245533 ! chloride transport GO:0006821 67 48 0,000 0,33360308 0,35837789 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,33360308 0,35821058 ! gastrulation GO:0007369 73 48 0,000 0,33360308 0,35804343 ! regulation of DNA replication GO:0006275 75 48 0,000 0,33360308 0,35787643 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,33360308 0,35770959 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,33360308 0,3575429 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,33360308 0,35737637 ! regulation of endocytosis GO:0030100 63 48 0,000 0,33360308 0,35721 ! nuclear export GO:0051168 69 48 0,000 0,33360308 0,35704378 ! sensory perception of smell GO:0007608 61 49 0,000 0,339222 0,36288865 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,339222 0,36271994 ! RNA elongation GO:0006354 62 49 0,000 0,339222 0,36255139 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,339222 0,362383 ! maintenance of location GO:0051235 84 49 0,000 0,339222 0,36221476 ! regulation of actin filament length GO:0030832 72 50 0,000 0,34479387 0,36799346 ! membrane fusion GO:0006944 80 50 0,000 0,34479387 0,36782277 ! proton transport GO:0015992 75 50 0,000 0,34479387 0,36765225 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,34479387 0,36748188 ! positive regulation of secretion GO:0051047 71 51 0,000 0,35031907 0,37319771 ! hydrogen transport GO:0006818 77 51 0,000 0,35031907 0,37302493 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,35031907 0,37285232 ! regulation of cellular component size GO:0032535 74 52 0,000 0,35579799 0,3785085 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,35579799 0,37833351 ! establishment of organelle localization GO:0051656 85 52 0,000 0,35579799 0,37815868 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,36123102 0,38375582 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,36123102 0,38357865 ! kidney development GO:0001822 90 53 0,000 0,36123102 0,38340164 ! single fertilization GO:0007338 59 53 0,000 0,36123102 0,38322479 ! amino acid transport GO:0006865 84 54 0,000 0,36661854 0,38876101 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,36661854 0,38858186 ! regulation of mitosis GO:0007088 84 54 0,000 0,36661854 0,38840287 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,36661854 0,38822405 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,36661854 0,38804539 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,36661854 0,3878669 ! mesoderm development GO:0007498 76 55 0,000 0,37196092 0,39333799 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,37196092 0,39315722 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,37196092 0,39297663 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,37725855 0,39839057 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,37725855 0,39820774 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,38251179 0,40356749 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,38251179 0,40338245 ! camera-type eye development GO:0043010 88 57 0,000 0,38251179 0,40319758 ! secondary metabolic process GO:0019748 84 57 0,000 0,38251179 0,40301288 ! gonad development GO:0008406 79 57 0,000 0,38251179 0,40282835 ! viral reproductive process GO:0022415 87 58 0,000 0,38772102 0,40812739 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,38772102 0,40794069 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,38772102 0,40775416 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,39288659 0,41299779 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,39288659 0,41280912 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,39800888 0,4180002 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,39800888 0,41780942 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,39800888 0,41761881 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,39800888 0,41742838 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,39800888 0,41723812 ! fertilization GO:0009566 68 60 0,000 0,39800888 0,41704803 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,40308825 0,42217804 ! meiosis GO:0007126 96 61 0,000 0,40308825 0,42198588 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,40308825 0,42179389 ! urogenital system development GO:0001655 101 61 0,000 0,40308825 0,42160208 ! extracellular matrix organization GO:0030198 103 61 0,000 0,40308825 0,42141044 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,40308825 0,42121898 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,40812505 0,42628865 ! neurotransmitter transport GO:0006836 81 62 0,000 0,40812505 0,42609515 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,40812505 0,42590182 ! meiotic cell cycle GO:0051321 97 62 0,000 0,40812505 0,42570866 ! organelle localization GO:0051640 96 62 0,000 0,40812505 0,42551569 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,41311963 0,43052793 ! viral reproduction GO:0016032 92 63 0,000 0,41311963 0,43033295 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,41807235 0,43529488 ! appendage morphogenesis GO:0035107 93 64 0,000 0,41807235 0,43509792 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,41807235 0,43490113 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,41807235 0,43470452 ! hexose catabolic process GO:0019320 82 64 0,000 0,41807235 0,43450809 ! reproductive structure development GO:0048608 90 65 0,000 0,42298355 0,43941381 ! appendage development GO:0048736 94 65 0,000 0,42298355 0,43921543 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,42298355 0,43901722 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,42298355 0,4388192 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,42298355 0,43862136 ! activation of immune response GO:0002253 83 65 0,000 0,42298355 0,43842369 ! protein oligomerization GO:0051259 100 65 0,000 0,42298355 0,4382262 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,42785359 0,44307215 ! antigen processing and presentation GO:0019882 96 66 0,000 0,42785359 0,44287275 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,42785359 0,44267353 ! regulation of immune effector process GO:0002697 101 66 0,000 0,42785359 0,44247448 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,4326828 0,44726761 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,43747152 0,4520146 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,43747152 0,45181163 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,43747152 0,45160884 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,43747152 0,45140624 ! rhythmic process GO:0048511 105 68 0,000 0,43747152 0,45120381 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,4422201 0,45589701 ! response to drug GO:0042493 108 69 0,000 0,4422201 0,45569275 ! eye development GO:0001654 111 70 0,000 0,44692886 0,46033872 ! amine transport GO:0015837 101 70 0,000 0,44692886 0,46013266 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,44692886 0,45992679 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,45159813 0,46452402 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,45159813 0,46431637 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,45622826 0,46886729 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,46537234 0,47805109 ! digestion GO:0007586 97 74 0,000 0,46537234 0,47783767 ! blood coagulation GO:0007596 116 75 0,000 0,46988695 0,48225791 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,46988695 0,48204281 ! amine biosynthetic process GO:0009309 97 76 0,000 0,47436369 0,48641841 ! response to unfolded protein GO:0006986 99 76 0,000 0,47436369 0,48620164 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,47880288 0,49053302 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,47880288 0,49031461 ! sex differentiation GO:0007548 105 77 0,000 0,47880288 0,49009641 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,47880288 0,48987839 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,47880288 0,48966057 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,48320483 0,49394272 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,48320483 0,49372328 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,48756986 0,49796211 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,48756986 0,49774109 ! T cell activation GO:0042110 134 79 0,000 0,48756986 0,49752026 ! regulation of lyase activity GO:0051339 133 79 0,000 0,48756986 0,49729963 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,48756986 0,4970792 ! chromatin assembly GO:0031497 102 80 0,000 0,49189826 0,50126983 GO:0006334|nucleosome assembly, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,49189826 0,50104783 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,49619035 0,50519602 ! hemostasis GO:0007599 125 81 0,000 0,49619035 0,50497248 ! mRNA transport GO:0051028 121 81 0,000 0,49619035 0,50474914 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,49619035 0,504526 ! response to protein stimulus GO:0051789 111 81 0,000 0,49619035 0,50430305 ! regulation of neurological system process GO:0031644 122 81 0,000 0,49619035 0,5040803 ! vitamin metabolic process GO:0006766 103 81 0,000 0,49619035 0,50385775 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,5046668 0,51223903 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,5046668 0,51201307 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,50885175 0,51603131 ! sterol metabolic process GO:0016125 120 84 0,000 0,50885175 0,51580389 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,51711659 0,52395073 ! nucleosome organization GO:0034728 114 87 0,000 0,52119706 0,52785259 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,52119706 0,52762026 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,52119706 0,52738814 ! female pregnancy GO:0007565 130 87 0,000 0,52119706 0,52715622 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,52524328 0,53101518 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,52524328 0,53078187 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,52524328 0,53054877 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,52524328 0,53031587 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! reproductive developmental process GO:0003006 127 89 0,000 0,52925554 0,5341324 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,52925554 0,53389813 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,52925554 0,53366407 ! leukocyte differentiation GO:0002521 143 90 0,000 0,53323412 0,53744017 ! hormone metabolic process GO:0042445 121 90 0,000 0,53323412 0,53720476 ! RNA localization GO:0006403 135 91 0,000 0,5371793 0,54094238 ! ATP metabolic process GO:0046034 137 91 0,000 0,5371793 0,54070564 ! response to virus GO:0009615 122 91 0,000 0,5371793 0,54046911 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,54109136 0,54416709 ! cell fate commitment GO:0045165 141 92 0,000 0,54109136 0,54392925 ! positive regulation of immune response GO:0050778 121 92 0,000 0,54109136 0,54369162 ! DNA recombination GO:0006310 146 92 0,000 0,54109136 0,5434542 ! carboxylic acid transport GO:0046942 147 95 0,000 0,55263157 0,55480254 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,55641389 0,558356 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,55641389 0,55811249 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,56016444 0,56162956 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,56757132 0,56880786 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,57122817 0,57222335 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,57122817 0,57197423 ! divalent metal ion transport GO:0070838 171 100 0,000 0,57122817 0,57172533 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,57122817 0,57147664 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,57122817 0,57122817