pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6885-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 2,000 3,362E-06 6,196E-03 ! angiogenesis GO:0001525 65 64 5,000 5,222E-06 4,812E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 2,000 1,855E-05 0,01139292 ! positive regulation of leukocyte migration GO:0002687 8 8 2,000 1,855E-05 8,545E-03 ! blood vessel morphogenesis GO:0048514 84 83 5,000 2,373E-05 8,748E-03 ! regulation of leukocyte migration GO:0002685 9 9 2,000 2,768E-05 8,502E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 2,000 2,768E-05 7,287E-03 ! heart development GO:0007507 90 87 5,000 3,108E-05 7,159E-03 ! response to oxygen levels GO:0070482 55 54 4,000 3,618E-05 7,41E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 4,101E-05 7,558E-03 ! blood vessel development GO:0001568 95 94 5,000 4,826E-05 8,085E-03 ! vasculature development GO:0001944 97 96 5,000 5,436E-05 8,348E-03 ! actomyosin structure organization GO:0031032 12 12 2,000 7,141E-05 0,01012333 ! negative regulation of translation GO:0017148 12 12 2,000 7,141E-05 9,4E-03 ! regulation of endothelial cell migration GO:0010594 13 13 2,000 9,236E-05 0,01134851 ! positive regulation of locomotion GO:0040017 13 13 2,000 9,236E-05 0,01063923 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! positive regulation of cell migration GO:0030335 36 36 3,000 1,131E-04 0,01226619 ! integrin-mediated signaling pathway GO:0007229 36 36 3,000 1,131E-04 0,01158473 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,17E-04 0,01134574 ! peptide cross-linking GO:0018149 14 14 2,000 1,17E-04 0,01077845 ! regulation of behavior GO:0050795 14 14 2,000 1,17E-04 0,01026519 ! regulation of cell migration GO:0030334 71 71 4,000 1,36E-04 0,01139707 ! glutathione metabolic process GO:0006749 16 15 2,000 1,455E-04 0,01165707 ! positive regulation of cell motion GO:0051272 39 39 3,000 1,555E-04 0,01194319 ! cell morphogenesis involved in differentiation GO:0000904 82 77 4,000 2E-04 0,01474033 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 2,152E-04 0,01525757 ! myelination GO:0042552 17 17 2,000 2,152E-04 0,01469247 ! regulation of locomotion GO:0040012 79 79 4,000 2,257E-04 0,01485334 ! regulation of cell motion GO:0051270 79 79 4,000 2,257E-04 0,01434116 ! ensheathment of neurons GO:0007272 18 18 2,000 2,57E-04 0,01578852 GO:0008366|axon ensheathment, ! regulation of endothelial cell proliferation GO:0001936 19 19 2,000 3,037E-04 0,01805334 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 3,359E-04 0,01934746 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 3,359E-04 0,01876118 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 2,000 3,555E-04 0,01926838 ! positive regulation of transferase activity GO:0051347 91 88 4,000 3,739E-04 0,01968728 GO:0033674|positive regulation of kinase activity, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 3,802E-04 0,01946557 ! regulation of action potential in neuron GO:0019228 21 21 2,000 4,126E-04 0,02055385 ! negative regulation of blood pressure GO:0045776 6 5 1,000 4,902E-04 0,02377492 ! mRNA stabilization GO:0048255 5 5 1,000 4,902E-04 0,02316531 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 4,902E-04 0,02258618 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,902E-04 0,02203529 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 4,902E-04 0,02151064 ! neuron recognition GO:0008038 5 5 1,000 4,902E-04 0,0210104 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 4,902E-04 0,02053289 ! regulation of interleukin-12 production GO:0032655 5 5 1,000 4,902E-04 0,0200766 ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,902E-04 0,01964015 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 1,000 4,902E-04 0,01922228 GO:0002688|regulation of leukocyte chemotaxis, ! neuromuscular process controlling posture GO:0050884 5 5 1,000 4,902E-04 0,01882181 ! removal of superoxide radicals GO:0019430 6 5 1,000 4,902E-04 0,0184377 ! regulation of fibrinolysis GO:0051917 5 5 1,000 4,902E-04 0,01806894 ! negative regulation of organic acid transport GO:0032891 5 5 1,000 4,902E-04 0,01771465 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 1,000 4,902E-04 0,01737398 ! response to hypoxia GO:0001666 53 53 3,000 5,146E-04 0,0178956 ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 6,145E-04 0,02097188 ! regulation of action potential GO:0001508 24 24 2,000 6,186E-04 0,02072844 ! negative regulation of immune system process GO:0002683 25 25 2,000 6,994E-04 0,02301891 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 7,32E-04 0,02366676 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of positive chemotaxis GO:0050926 6 6 1,000 7,32E-04 0,02325872 GO:0050927|positive regulation of positive chemotaxis, ! ER overload response GO:0006983 6 6 1,000 7,32E-04 0,0228645 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 7,32E-04 0,02248343 GO:0070667|negative regulation of mast cell proliferation, ! negative regulation of endothelial cell migration GO:0010596 6 6 1,000 7,32E-04 0,02211485 ! phagocytosis, engulfment GO:0006911 6 6 1,000 7,32E-04 0,02175815 ! regulation of vascular permeability GO:0043114 6 6 1,000 7,32E-04 0,02141279 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 7,32E-04 0,02107821 ! rRNA modification GO:0000154 6 6 1,000 7,32E-04 0,02075393 ! regulation of bone resorption GO:0045124 6 6 1,000 7,32E-04 0,02043948 ! negative regulation of axonogenesis GO:0050771 7 6 1,000 7,32E-04 0,02013441 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,32E-04 0,01983832 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 7,32E-04 0,01955081 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 7,32E-04 0,01927151 ! regulation of lipid transport GO:0032368 6 6 1,000 7,32E-04 0,01900008 ! neuroblast proliferation GO:0007405 6 6 1,000 7,32E-04 0,01873619 ! regulation of RNA splicing GO:0043484 6 6 1,000 7,32E-04 0,01847953 ! localization within membrane GO:0051668 6 6 1,000 7,32E-04 0,01822981 ! negative regulation of cell migration GO:0030336 26 26 2,000 7,867E-04 0,01933231 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 3,000 8,263E-04 0,02003671 ! peptide metabolic process GO:0006518 29 27 2,000 8,806E-04 0,02107822 ! axonogenesis GO:0007409 66 62 3,000 9,354E-04 0,02210205 ! negative regulation of cell projection organization GO:0031345 8 7 1,000 1,02E-03 0,02379772 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 1,02E-03 0,02350025 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,02E-03 0,02321012 ! response to hexose stimulus GO:0009746 7 7 1,000 1,02E-03 0,02292707 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,02E-03 0,02265084 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! myofibril assembly GO:0030239 7 7 1,000 1,02E-03 0,02238119 GO:0055002|striated muscle cell development, ! axon cargo transport GO:0008088 7 7 1,000 1,02E-03 0,02211788 ! detection of chemical stimulus GO:0009593 8 7 1,000 1,02E-03 0,0218607 ! response to gamma radiation GO:0010332 8 7 1,000 1,02E-03 0,02160943 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 1,02E-03 0,02136386 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 1,02E-03 0,02112382 ! regulation of axon extension GO:0030516 7 7 1,000 1,02E-03 0,02088911 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,02E-03 0,02065956 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,089E-03 0,02181902 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 1,184E-03 0,02345511 ! negative regulation of protein metabolic process GO:0051248 66 66 3,000 1,184E-03 0,02320558 ! response to reactive oxygen species GO:0000302 31 30 2,000 1,204E-03 0,02336069 ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 1,204E-03 0,02311735 ! vascular process in circulatory system GO:0003018 31 30 2,000 1,204E-03 0,02287903 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 3,000 1,252E-03 0,02354855 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 3,000 1,252E-03 0,02331069 ! negative regulation of cell motion GO:0051271 31 31 2,000 1,327E-03 0,02444793 ! positive regulation of translation GO:0045727 8 8 1,000 1,354E-03 0,02470595 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,354E-03 0,02446373 ! lipid localization GO:0010876 8 8 1,000 1,354E-03 0,02422622 GO:0019915|lipid storage, ! adult walking behavior GO:0007628 8 8 1,000 1,354E-03 0,02399327 ! muscle cell development GO:0055001 8 8 1,000 1,354E-03 0,02376477 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,354E-03 0,02354057 ! regulation of RNA stability GO:0043487 8 8 1,000 1,354E-03 0,02332057 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 1,354E-03 0,02310463 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,354E-03 0,02289267 ! regulation of organic acid transport GO:0032890 8 8 1,000 1,354E-03 0,02268455 ! regulation of translation GO:0006417 69 69 3,000 1,398E-03 0,02320621 ! cell redox homeostasis GO:0045454 32 32 2,000 1,456E-03 0,02396657 ! cell part morphogenesis GO:0032990 75 70 3,000 1,475E-03 0,02405135 ! muscle tissue development GO:0060537 72 70 3,000 1,475E-03 0,02384038 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,733E-03 0,02777103 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 1,000 1,733E-03 0,02753163 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,733E-03 0,02729632 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,733E-03 0,02706499 ! histone acetylation GO:0016573 9 9 1,000 1,733E-03 0,02683755 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,733E-03 0,02661391 ! actin filament-based movement GO:0030048 9 9 1,000 1,733E-03 0,02639396 ! regulation of angiogenesis GO:0045765 35 34 2,000 1,74E-03 0,02628058 ! electron transport chain GO:0022900 75 74 3,000 1,812E-03 0,02715667 ! coenzyme metabolic process GO:0006732 75 74 3,000 1,812E-03 0,02693766 ! regulation of cell morphogenesis GO:0022604 38 35 2,000 1,893E-03 0,02791477 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 1,893E-03 0,02769323 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 2,055E-03 0,02982365 GO:0045937|positive regulation of phosphate metabolic process, ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 2,156E-03 0,03104656 ! response to carbohydrate stimulus GO:0009743 10 10 1,000 2,156E-03 0,03080588 ! cell-substrate junction assembly GO:0007044 11 10 1,000 2,156E-03 0,03056892 ! neuromuscular junction development GO:0007528 10 10 1,000 2,156E-03 0,03033557 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 2,156E-03 0,03010575 ! sphingolipid catabolic process GO:0030149 10 10 1,000 2,156E-03 0,02987939 GO:0046466|membrane lipid catabolic process, ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 2,156E-03 0,02965641 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,156E-03 0,02943673 ! lung development GO:0030324 38 37 2,000 2,225E-03 0,03015648 ! axon guidance GO:0007411 39 38 2,000 2,404E-03 0,03234055 ! neuron projection development GO:0031175 85 80 3,000 2,415E-03 0,03224717 ! tube development GO:0035295 83 81 3,000 2,527E-03 0,03350347 ! respiratory tube development GO:0030323 40 39 2,000 2,591E-03 0,03411422 ! respiratory system development GO:0060541 40 39 2,000 2,591E-03 0,03387227 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 2,623E-03 0,03404941 ! microtubule-based transport GO:0010970 11 11 1,000 2,623E-03 0,03381131 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,623E-03 0,03357651 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 2,623E-03 0,03334494 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 1,000 2,623E-03 0,03311655 GO:0003015|heart process, ! dendrite development GO:0016358 11 11 1,000 2,623E-03 0,03289127 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 1,000 2,623E-03 0,03266903 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 2,623E-03 0,03244978 ! intermediate filament-based process GO:0045103 11 11 1,000 2,623E-03 0,03223345 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 1,000 2,623E-03 0,03201998 GO:0060415|muscle tissue morphogenesis, ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,623E-03 0,03180932 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 2,623E-03 0,03160142 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,623E-03 0,03139621 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 3,134E-03 0,03726258 ! iron ion transport GO:0006826 13 12 1,000 3,134E-03 0,03702371 ! heterophilic cell adhesion GO:0007157 12 12 1,000 3,134E-03 0,0367879 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 3,134E-03 0,03655506 ! somitogenesis GO:0001756 13 12 1,000 3,134E-03 0,03632515 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 3,134E-03 0,03609812 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 3,687E-03 0,0422042 ! post-embryonic development GO:0009791 14 13 1,000 3,687E-03 0,04194368 ! negative regulation of protein modification process GO:0031400 13 13 1,000 3,687E-03 0,04168636 ! patterning of blood vessels GO:0001569 13 13 1,000 3,687E-03 0,04143217 ! vasculogenesis GO:0001570 13 13 1,000 3,687E-03 0,04118107 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 3,687E-03 0,04093299 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,687E-03 0,04068788 ! coenzyme catabolic process GO:0009109 13 13 1,000 3,687E-03 0,04044569 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! regulation of axonogenesis GO:0050770 14 13 1,000 3,687E-03 0,04020637 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 1,000 3,687E-03 0,03996986 ! vasodilation GO:0042311 14 13 1,000 3,687E-03 0,03973612 ! glycosphingolipid metabolic process GO:0006687 13 13 1,000 3,687E-03 0,03950509 GO:0006664|glycolipid metabolic process, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,687E-03 0,03927674 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 3,687E-03 0,03905101 GO:0001952|regulation of cell-matrix adhesion, ! alkene biosynthetic process GO:0043450 13 13 1,000 3,687E-03 0,03882786 GO:0019370|leukotriene biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 1,000 3,687E-03 0,03860725 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 3,905E-03 0,04066166 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 3,000 4,008E-03 0,04149593 ! regulation of membrane potential GO:0042391 46 46 2,000 4,157E-03 0,04279881 ! acetyl-CoA metabolic process GO:0006084 14 14 1,000 4,282E-03 0,04384126 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 4,282E-03 0,04359905 ! protein amino acid acylation GO:0043543 14 14 1,000 4,282E-03 0,04335949 ! regulation of neuron projection development GO:0010975 15 14 1,000 4,282E-03 0,04312255 ! superoxide metabolic process GO:0006801 15 14 1,000 4,282E-03 0,04288819 ! lysosome organization GO:0007040 14 14 1,000 4,282E-03 0,04265636 ! leukotriene metabolic process GO:0006691 14 14 1,000 4,282E-03 0,04242703 ! regulation of blood coagulation GO:0030193 15 14 1,000 4,282E-03 0,04220015 ! neuromuscular process controlling balance GO:0050885 14 14 1,000 4,282E-03 0,04197568 ! epidermis development GO:0008544 94 94 3,000 4,329E-03 0,0422113 ! cofactor metabolic process GO:0051186 95 94 3,000 4,329E-03 0,04198914 ! striated muscle cell differentiation GO:0051146 16 15 1,000 4,918E-03 0,04745678 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 4,918E-03 0,04720961 ! response to ionizing radiation GO:0010212 16 15 1,000 4,918E-03 0,046965 ! cellular alkene metabolic process GO:0043449 15 15 1,000 4,918E-03 0,04672291 ! negative regulation of cell activation GO:0050866 15 15 1,000 4,918E-03 0,04648331 ! cell cycle arrest GO:0007050 49 49 2,000 4,97E-03 0,04673639 ! skeletal muscle tissue development GO:0007519 50 49 2,000 4,97E-03 0,04649915 GO:0060538|skeletal muscle organ development, ! blood circulation GO:0008015 99 98 3,000 5,022E-03 0,04674714 GO:0003013|circulatory system process, ! ectoderm development GO:0007398 99 99 3,000 5,207E-03 0,04821962 ! muscle organ development GO:0007517 102 100 3,000 5,395E-03 0,04971884 ! vacuole organization GO:0007033 16 16 1,000 5,595E-03 0,05130464 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 5,595E-03 0,05105066 ! segmentation GO:0035282 17 16 1,000 5,595E-03 0,05079917 ! iron ion homeostasis GO:0055072 16 16 1,000 5,595E-03 0,05055016 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 5,595E-03 0,05030357 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 5,595E-03 0,05005938 ! cofactor catabolic process GO:0051187 16 16 1,000 5,595E-03 0,04981755 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 5,595E-03 0,04957804 ! regulation of coagulation GO:0050818 17 16 1,000 5,595E-03 0,04934082 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 6,313E-03 0,05540145 ! leukocyte adhesion GO:0007159 17 17 1,000 6,313E-03 0,05513888 ! cell junction assembly GO:0034329 18 17 1,000 6,313E-03 0,05487879 ! tissue remodeling GO:0048771 17 17 1,000 6,313E-03 0,05462114 ! negative regulation of cell development GO:0010721 18 17 1,000 6,313E-03 0,05436591 GO:0050768|negative regulation of neurogenesis, ! cell recognition GO:0008037 18 17 1,000 6,313E-03 0,05411304 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 6,313E-03 0,05386252 ! adult locomotory behavior GO:0008344 17 17 1,000 6,313E-03 0,0536143 ! sulfur metabolic process GO:0006790 55 54 2,000 6,527E-03 0,05518155 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 6,527E-03 0,05492958 ! regulation of cell adhesion GO:0030155 56 55 2,000 6,87E-03 0,05754783 ! regulation of cell projection organization GO:0031344 19 18 1,000 7,07E-03 0,05895649 ! icosanoid biosynthetic process GO:0046456 18 18 1,000 7,07E-03 0,05869092 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 7,07E-03 0,05842773 ! response to calcium ion GO:0051592 18 18 1,000 7,07E-03 0,0581669 ! ceramide metabolic process GO:0006672 18 18 1,000 7,07E-03 0,05790838 GO:0046519|sphingoid metabolic process, ! BMP signaling pathway GO:0030509 18 18 1,000 7,07E-03 0,05765215 ! regulation of microtubule-based process GO:0032886 18 18 1,000 7,07E-03 0,05739817 ! cellular response to oxidative stress GO:0034599 19 19 1,000 7,866E-03 0,06358075 ! peripheral nervous system development GO:0007422 19 19 1,000 7,866E-03 0,06330311 ! regulation of cell shape GO:0008360 21 19 1,000 7,866E-03 0,06302788 ! response to heat GO:0009408 19 19 1,000 7,866E-03 0,06275503 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 8,345E-03 0,0662917 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 8,7E-03 0,06881688 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 8,7E-03 0,06852279 ! phagocytosis GO:0006909 21 20 1,000 8,7E-03 0,0682312 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 1,000 8,7E-03 0,06794209 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 8,7E-03 0,06765541 ! RNA modification GO:0009451 20 20 1,000 8,7E-03 0,06737115 ! cellular respiration GO:0045333 62 61 2,000 9,147E-03 0,07053705 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 9,572E-03 0,07350877 ! mammary gland development GO:0030879 23 21 1,000 9,572E-03 0,07320376 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 9,993E-03 0,07610633 ! regulation of response to external stimulus GO:0032101 65 64 2,000 0,01043297 0,07912739 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,0104822 0,079175 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 1,000 0,0104822 0,07885183 ! aerobic respiration GO:0009060 22 22 1,000 0,0104822 0,0785313 ! cytokinesis GO:0000910 23 22 1,000 0,0104822 0,07821336 ! polysaccharide metabolic process GO:0005976 69 66 2,000 0,01134562 0,08431441 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,0114287 0,08459073 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,0114287 0,08425237 ! cell projection assembly GO:0030031 25 23 1,000 0,0114287 0,0839167 ! response to radiation GO:0009314 70 68 2,000 0,01230314 0,08997894 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01241144 0,09041216 ! glucan metabolic process GO:0044042 25 24 1,000 0,01241144 0,09005621 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01279885 0,09250303 ! wound healing GO:0042060 74 70 2,000 0,0133059 0,09579208 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01342987 0,09630838 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01342987 0,09593509 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01342987 0,09556468 ! heart morphogenesis GO:0003007 25 25 1,000 0,01342987 0,09519713 ! icosanoid metabolic process GO:0006690 25 25 1,000 0,01342987 0,09483239 ! positive regulation of cytokine production GO:0001819 25 25 1,000 0,01342987 0,09447043 ! negative regulation of signal transduction GO:0009968 71 71 2,000 0,01382434 0,09687551 ! regulation of cell activation GO:0050865 71 71 2,000 0,01382434 0,09650855 ! positive regulation of binding GO:0051099 27 26 1,000 0,01448347 0,10072842 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,01448347 0,10034974 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,01448347 0,0999739 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01448347 0,09960086 ! double-strand break repair GO:0006302 27 26 1,000 0,01448347 0,0992306 ! regulation of blood vessel size GO:0050880 27 26 1,000 0,01448347 0,09886308 GO:0035150|regulation of tube size, ! synapse organization GO:0050808 26 26 1,000 0,01448347 0,09849827 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01557169 0,10550967 ! learning or memory GO:0007611 28 27 1,000 0,01557169 0,10512319 ! cell growth GO:0016049 27 27 1,000 0,01557169 0,10473953 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01557169 0,10435866 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01557169 0,10398055 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! defense response to bacterium GO:0042742 27 27 1,000 0,01557169 0,10360517 ! response to oxidative stress GO:0006979 76 75 2,000 0,01601266 0,10615584 ! negative regulation of cell communication GO:0010648 76 76 2,000 0,01658852 0,10957936 ! tRNA aminoacylation for protein translation GO:0006418 28 28 1,000 0,01669402 0,10988245 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 1,000 0,01669402 0,10949141 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,01669402 0,10910314 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01669402 0,10871762 ! histone modification GO:0016570 28 28 1,000 0,01669402 0,10833481 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01669402 0,10795469 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01777497 0,11454289 ! microtubule-based movement GO:0007018 82 78 2,000 0,01777497 0,11414379 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01784994 0,11422721 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01784994 0,11383196 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01784994 0,11343944 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,01784994 0,11304961 ! adult behavior GO:0030534 30 29 1,000 0,01784994 0,11266245 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01784994 0,11227794 ! response to UV GO:0009411 29 29 1,000 0,01784994 0,11189604 ! transition metal ion transport GO:0000041 31 30 1,000 0,01903892 0,11894486 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01903892 0,11854302 GO:0010863|positive regulation of phospholipase C activity, ! response to temperature stimulus GO:0009266 30 30 1,000 0,01903892 0,11814389 ! regulation of translational initiation GO:0006446 31 31 1,000 0,02026047 0,12530215 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02026047 0,12488308 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02026047 0,1244668 ! aging GO:0007568 32 31 1,000 0,02026047 0,12405329 ! sphingolipid metabolic process GO:0006665 31 31 1,000 0,02026047 0,12364252 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,02026047 0,12323446 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,02026047 0,12282908 ! muscle fiber development GO:0048747 32 32 1,000 0,02151407 0,1300014 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02151407 0,12957656 ! glycosaminoglycan metabolic process GO:0030203 34 32 1,000 0,02151407 0,12915448 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02151407 0,12873515 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,02151407 0,12831853 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02151407 0,1279046 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02151407 0,12749333 ! cellular amino acid derivative metabolic process GO:0006575 87 84 2,000 0,02161332 0,12767098 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,02229386 0,13127023 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02279923 0,13381838 ! membrane lipid metabolic process GO:0006643 33 33 1,000 0,02279923 0,13339356 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02279923 0,13297143 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02279923 0,13255196 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02411545 0,13976342 ! response to metal ion GO:0010038 34 34 1,000 0,02411545 0,13932529 ! muscle cell differentiation GO:0042692 35 34 1,000 0,02411545 0,1388899 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,02411545 0,13845722 ! detection of stimulus GO:0051606 36 34 1,000 0,02411545 0,13802723 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,02546224 0,14528457 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02546224 0,14483616 ! inorganic anion transport GO:0015698 35 35 1,000 0,02546224 0,14439051 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02546224 0,14394759 ! response to inorganic substance GO:0010035 36 36 1,000 0,02683913 0,15126765 ! aminoglycan metabolic process GO:0006022 38 36 1,000 0,02683913 0,15080647 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,02683913 0,15034809 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02683913 0,14989249 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,02738471 0,15247742 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02824564 0,15679731 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,02824564 0,15632645 ! adaptive immune response GO:0002250 37 37 1,000 0,02824564 0,15585841 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! pattern specification process GO:0007389 96 94 2,000 0,02894426 0,15923666 ! exocytosis GO:0006887 40 38 1,000 0,02968128 0,16280536 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,02968128 0,16232225 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,02968128 0,16184201 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,02968128 0,1613646 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,02968128 0,16089 ! regulation of cell growth GO:0001558 97 96 2,000 0,03055036 0,16511531 ! activation of MAPK activity GO:0000187 39 39 1,000 0,0311456 0,16784016 ! fatty acid biosynthetic process GO:0006633 39 39 1,000 0,0311456 0,16735083 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,03263812 0,17486064 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,03263812 0,1743538 ! anti-apoptosis GO:0006916 100 99 2,000 0,03304653 0,17602531 ! rRNA transcription GO:0009303 5 5 0,000 0,03511689 0,18651419 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03511689 0,18597823 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03511689 0,18544534 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03511689 0,18491549 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03511689 0,18438867 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03511689 0,18386484 ! reproductive cellular process GO:0048610 5 5 0,000 0,03511689 0,18334398 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03511689 0,18282605 ! prostate gland development GO:0030850 5 5 0,000 0,03511689 0,18231105 ! metencephalon development GO:0022037 5 5 0,000 0,03511689 0,18179894 ! water transport GO:0006833 5 5 0,000 0,03511689 0,1812897 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03511689 0,18078331 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03511689 0,18027973 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03511689 0,17977895 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03511689 0,17928095 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03511689 0,1787857 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03511689 0,17829318 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03511689 0,17780336 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03511689 0,17731623 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03511689 0,17683176 ! filopodium assembly GO:0046847 7 5 0,000 0,03511689 0,17634993 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03511689 0,17587072 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03511689 0,1753941 ! GTP metabolic process GO:0046039 5 5 0,000 0,03511689 0,17492006 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03511689 0,17444858 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03511689 0,17397963 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03511689 0,1735132 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03511689 0,17304926 ! social behavior GO:0035176 5 5 0,000 0,03511689 0,1725878 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03511689 0,17212879 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03511689 0,17167221 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03511689 0,17121805 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03511689 0,17076629 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03511689 0,1703169 ! response to lipid GO:0033993 5 5 0,000 0,03511689 0,16986988 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03511689 0,16942519 ! hippocampus development GO:0021766 6 5 0,000 0,03511689 0,16898283 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03511689 0,16854277 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03511689 0,168105 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03511689 0,16766949 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03511689 0,16723624 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03511689 0,16680521 ! heart looping GO:0001947 5 5 0,000 0,03511689 0,16637641 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03511689 0,1659498 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03511689 0,16552538 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03511689 0,16510312 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03511689 0,16468301 ! pH reduction GO:0045851 5 5 0,000 0,03511689 0,16426503 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03511689 0,16384917 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03511689 0,16343541 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03511689 0,16302374 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03511689 0,16261413 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03511689 0,16220657 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03511689 0,16180106 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03511689 0,16139756 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03511689 0,16099608 ! adrenal gland development GO:0030325 5 5 0,000 0,03511689 0,16059658 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03511689 0,16019907 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03511689 0,15980351 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03511689 0,15940991 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03511689 0,15901824 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03511689 0,15862849 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03511689 0,15824064 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03511689 0,15785469 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03511689 0,15747062 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03511689 0,15708841 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03511689 0,15670805 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03511689 0,15632952 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03511689 0,15595283 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03511689 0,15557794 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03511689 0,15520485 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03511689 0,15483355 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03511689 0,15446402 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03511689 0,15409625 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03511689 0,15373022 ! response to ATP GO:0033198 5 5 0,000 0,03511689 0,15336593 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03511689 0,15300336 ! regulation of appetite GO:0032098 5 5 0,000 0,03511689 0,15264251 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03511689 0,15228335 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03511689 0,15192588 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03511689 0,15157008 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03511689 0,15121594 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03511689 0,15086346 ! receptor clustering GO:0043113 5 5 0,000 0,03511689 0,15051261 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03511689 0,15016339 ! fear response GO:0042596 5 5 0,000 0,03511689 0,14981579 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03511689 0,1494698 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03511689 0,1491254 ! retinol metabolic process GO:0042572 5 5 0,000 0,03511689 0,14878258 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03511689 0,14844134 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03511689 0,14810165 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03511689 0,14776352 ! parturition GO:0007567 5 5 0,000 0,03511689 0,14742693 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03511689 0,14709187 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03511689 0,14675833 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03511689 0,1464263 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03511689 0,14609576 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03511689 0,14576672 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03511689 0,14543915 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03511689 0,14511306 ! response to UV-B GO:0010224 5 5 0,000 0,03511689 0,14478842 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03511689 0,14446523 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03511689 0,14414348 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03511689 0,14382316 ! interaction with symbiont GO:0051702 5 5 0,000 0,03511689 0,14350426 ! cellular extravasation GO:0045123 5 5 0,000 0,03511689 0,14318678 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03511689 0,14287069 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03511689 0,142556 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03511689 0,14224269 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03511689 0,14193075 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03511689 0,14162018 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03511689 0,14131097 ! response to amine stimulus GO:0014075 5 5 0,000 0,03511689 0,1410031 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03511689 0,14069657 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03511689 0,14039137 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03511689 0,1400875 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03511689 0,13978493 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03511689 0,13948367 ! decidualization GO:0046697 5 5 0,000 0,03511689 0,13918371 ! hair follicle maturation GO:0048820 5 5 0,000 0,03511689 0,13888503 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03511689 0,13858763 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03511689 0,1382915 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03511689 0,13799664 GO:0009155|purine deoxyribonucleotide catabolic process, ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03511689 0,13770303 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03511689 0,13741067 ! postreplication repair GO:0006301 5 5 0,000 0,03511689 0,13711954 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03511689 0,13682965 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03511689 0,13654098 ! histone methylation GO:0016571 5 5 0,000 0,03511689 0,13625352 ! DNA methylation GO:0006306 5 5 0,000 0,03511689 0,13596728 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03511689 0,13568223 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03511689 0,13539837 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03511689 0,13511571 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03511689 0,13483422 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03511689 0,13455389 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03511689 0,13427474 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03511689 0,13399674 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03511689 0,13371988 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03511689 0,13344417 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03511689 0,1331696 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03511689 0,13289615 ! sterol catabolic process GO:0016127 5 5 0,000 0,03511689 0,13262382 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03511689 0,1323526 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03511689 0,1320825 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03511689 0,13181349 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03511689 0,13154558 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03511689 0,13127875 ! zymogen activation GO:0031638 5 5 0,000 0,03511689 0,131013 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03511689 0,13074833 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03511689 0,13048472 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03511689 0,13022218 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03511689 0,12996069 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03511689 0,12970025 ! nucleosome positioning GO:0016584 5 5 0,000 0,03511689 0,12944085 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03511689 0,12918248 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03511689 0,12892515 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03511689 0,12866883 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03511689 0,12841354 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03511689 0,12815925 ! NADPH regeneration GO:0006740 5 5 0,000 0,03511689 0,12790597 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03511689 0,12765369 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03511689 0,12740241 ! musculoskeletal movement GO:0050881 5 5 0,000 0,03511689 0,12715211 GO:0050879|multicellular organismal movement, ! sarcomere organization GO:0045214 5 5 0,000 0,03511689 0,12690279 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03511689 0,12665445 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03511689 0,12640708 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03511689 0,12616067 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03511689 0,12591522 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03511689 0,12567072 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03511689 0,12542718 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03511689 0,12518457 ! spleen development GO:0048536 5 5 0,000 0,03511689 0,1249429 ! male genitalia development GO:0030539 5 5 0,000 0,03511689 0,12470216 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03511689 0,12446235 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03511689 0,12422346 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03511689 0,12398549 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03511689 0,12374842 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03511689 0,12351226 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03511689 0,123277 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03511689 0,12304263 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03511689 0,12280915 ! ATP catabolic process GO:0006200 5 5 0,000 0,03511689 0,12257656 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03511689 0,12234485 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03511689 0,12211401 ! blastocyst formation GO:0001825 5 5 0,000 0,03511689 0,12188404 ! embryonic gut development GO:0048566 5 5 0,000 0,03511689 0,12165493 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03511689 0,12142669 ! activation of innate immune response GO:0002218 5 5 0,000 0,03511689 0,12119929 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03511689 0,12097275 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03511689 0,12074706 ! muscle adaptation GO:0043500 5 5 0,000 0,03511689 0,1205222 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03511689 0,12029818 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03511689 0,120075 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03511689 0,11985264 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03511689 0,1196311 ! defense response to fungus GO:0050832 5 5 0,000 0,03511689 0,11941037 ! lysogeny GO:0030069 5 5 0,000 0,03511689 0,11919047 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03511689 0,11897137 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03511689 0,11875307 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03511689 0,11853557 ! response to nicotine GO:0035094 5 5 0,000 0,03511689 0,11831887 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03511689 0,11810296 ! mitochondrion localization GO:0051646 5 5 0,000 0,03511689 0,11788784 ! nucleus localization GO:0051647 5 5 0,000 0,03511689 0,1176735 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03511689 0,11745993 ! respiratory electron transport chain GO:0022904 43 42 1,000 0,03570598 0,11921397 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,03570598 0,1189984 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,03570598 0,1187836 ! mitochondrion organization GO:0007005 44 43 1,000 0,0372804 0,1237978 ! humoral immune response GO:0006959 44 44 1,000 0,03888123 0,12888149 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,03888123 0,1286501 ! regulation of DNA binding GO:0051101 47 45 1,000 0,04050803 0,13379264 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,04050803 0,1335533 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,04050803 0,13331481 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04199387 0,13795848 ! axon extension GO:0048675 7 6 0,000 0,04199387 0,137713 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04199387 0,1374684 ! tRNA modification GO:0006400 6 6 0,000 0,04199387 0,13722466 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04199387 0,13698178 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04199387 0,13673976 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04199387 0,1364986 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04199387 0,13625829 ! virus-host interaction GO:0019048 6 6 0,000 0,04199387 0,13601882 ! regulation of S phase GO:0033261 6 6 0,000 0,04199387 0,13578019 ! myotube differentiation GO:0014902 6 6 0,000 0,04199387 0,13554239 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04199387 0,13530543 ! bone remodeling GO:0046849 6 6 0,000 0,04199387 0,1350693 ! N-glycan processing GO:0006491 6 6 0,000 0,04199387 0,13483398 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04199387 0,13459949 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04199387 0,13436581 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04199387 0,13413294 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04199387 0,13390088 ! RNA methylation GO:0001510 6 6 0,000 0,04199387 0,13366961 ! cartilage condensation GO:0001502 7 6 0,000 0,04199387 0,13343915 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04199387 0,13320948 ! succinate metabolic process GO:0006105 7 6 0,000 0,04199387 0,1329806 ! artery development GO:0060840 6 6 0,000 0,04199387 0,1327525 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04199387 0,13252518 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04199387 0,13229864 ! androgen metabolic process GO:0008209 6 6 0,000 0,04199387 0,13207288 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04199387 0,13184788 ! limbic system development GO:0021761 7 6 0,000 0,04199387 0,13162365 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04199387 0,13140018 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04199387 0,13117747 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04199387 0,13095551 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04199387 0,1307343 ! pathogenesis GO:0009405 6 6 0,000 0,04199387 0,13051384 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04199387 0,13029412 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04199387 0,13007514 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04199387 0,12985689 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04199387 0,12963937 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04199387 0,12942259 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04199387 0,12920652 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04199387 0,12899118 ! arginine metabolic process GO:0006525 6 6 0,000 0,04199387 0,12877655 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04199387 0,12856264 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04199387 0,12834943 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04199387 0,12813693 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04199387 0,12792514 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04199387 0,12771404 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04199387 0,12750364 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04199387 0,12729393 ! V(D)J recombination GO:0033151 6 6 0,000 0,04199387 0,1270849 ! focal adhesion formation GO:0048041 7 6 0,000 0,04199387 0,12687657 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04199387 0,12666891 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04199387 0,12646194 ! regulation of heart rate GO:0002027 6 6 0,000 0,04199387 0,12625564 ! lipid digestion GO:0044241 6 6 0,000 0,04199387 0,12605001 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04199387 0,12584505 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04199387 0,12564076 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04199387 0,12543713 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04199387 0,12523415 ! ruffle organization GO:0031529 6 6 0,000 0,04199387 0,12503184 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04199387 0,12483017 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04199387 0,12462916 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04199387 0,12442879 ! L-amino acid transport GO:0015807 6 6 0,000 0,04199387 0,12422906 ! bone mineralization GO:0030282 6 6 0,000 0,04199387 0,12402998 GO:0031214|biomineral formation, ! negative regulation of ossification GO:0030279 6 6 0,000 0,04199387 0,12383153 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04199387 0,12363372 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04199387 0,12343653 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04199387 0,12323998 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04199387 0,12304405 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04199387 0,12284874 ! regulation of organ growth GO:0046620 6 6 0,000 0,04199387 0,12265405 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04199387 0,12245998 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04199387 0,12226652 ! response to dsRNA GO:0043331 6 6 0,000 0,04199387 0,12207367 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04199387 0,12188143 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04199387 0,12168979 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04199387 0,12149875 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04199387 0,12130832 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04199387 0,12111848 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04199387 0,12092923 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04199387 0,12074057 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04199387 0,1205525 ! erythrocyte development GO:0048821 6 6 0,000 0,04199387 0,12036502 ! renal water homeostasis GO:0003091 6 6 0,000 0,04199387 0,12017812 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04199387 0,11999179 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04199387 0,11980605 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04199387 0,11962088 ! ribosome assembly GO:0042255 6 6 0,000 0,04199387 0,11943628 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04199387 0,11925224 ! diencephalon development GO:0021536 6 6 0,000 0,04199387 0,11906878 ! fucose catabolic process GO:0019317 6 6 0,000 0,04199387 0,11888588 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04199387 0,11870354 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04199387 0,11852176 ! regulation of cell division GO:0051302 6 6 0,000 0,04199387 0,11834053 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04199387 0,11815986 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04199387 0,11797974 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04199387 0,11780016 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04199387 0,11762113 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04199387 0,11744265 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04199387 0,11726471 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04199387 0,1170873 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04199387 0,11691043 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04199387 0,1167341 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04199387 0,11655829 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04199387 0,11638302 ! thymus development GO:0048538 6 6 0,000 0,04199387 0,11620827 ! lymph node development GO:0048535 6 6 0,000 0,04199387 0,11603404 ! organic cation transport GO:0015695 6 6 0,000 0,04199387 0,11586034 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04199387 0,11568716 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04199387 0,11551449 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04199387 0,11534233 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04199387 0,11517069 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04199387 0,11499956 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04199387 0,11482894 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04199387 0,11465882 ! alditol metabolic process GO:0019400 6 6 0,000 0,04199387 0,11448921 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04199387 0,1143201 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04199387 0,11415148 ! maternal placenta development GO:0001893 6 6 0,000 0,04199387 0,11398337 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04199387 0,11381575 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04199387 0,11364861 ! tube morphogenesis GO:0035239 47 46 1,000 0,04216036 0,11393187 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,04216036 0,11376506 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,04216036 0,11359874 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,04383779 0,11794604 ! regulation of blood pressure GO:0008217 48 47 1,000 0,04383779 0,11777411 ! actin filament organization GO:0007015 50 48 1,000 0,04553989 0,12216888 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,04553989 0,12199131 ! ossification GO:0001503 50 49 1,000 0,04726626 0,12643209 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,04726626 0,12624886 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,04726626 0,12606615 ! response to bacterium GO:0009617 50 49 1,000 0,04726626 0,12588398 ! regulation of ligase activity GO:0051340 50 49 1,000 0,04726626 0,12570233 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,04726626 0,1255212 GO:0002696|positive regulation of leukocyte activation, ! respiratory burst GO:0045730 7 7 0,000 0,04882284 0,12946833 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04882284 0,12928231 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04882284 0,12909683 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04882284 0,12891187 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04882284 0,12872745 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04882284 0,12854355 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04882284 0,12836018 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04882284 0,12817733 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04882284 0,127995 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04882284 0,12781319 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04882284 0,1276319 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04882284 0,12745112 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04882284 0,12727085 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04882284 0,12709108 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04882284 0,12691183 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04882284 0,12673308 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04882284 0,12655484 ! axis specification GO:0009798 7 7 0,000 0,04882284 0,12637709 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04882284 0,12619984 ! visual behavior GO:0007632 7 7 0,000 0,04882284 0,12602309 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04882284 0,12584684 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04882284 0,12567107 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04882284 0,1254958 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04882284 0,12532101 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04882284 0,12514671 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04882284 0,1249729 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04882284 0,12479957 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04882284 0,12462671 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04882284 0,12445434 ! digestive system development GO:0055123 7 7 0,000 0,04882284 0,12428244 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04882284 0,12411102 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04882284 0,12394007 ! protein targeting to ER GO:0045047 8 7 0,000 0,04882284 0,12376958 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04882284 0,12359957 ! endoderm development GO:0007492 7 7 0,000 0,04882284 0,12343002 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04882284 0,12326094 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04882284 0,12309232 GO:0006688|glycosphingolipid biosynthetic process, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04882284 0,12292416 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04882284 0,12275646 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04882284 0,12258922 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04882284 0,12242243 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04882284 0,1222561 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04882284 0,12209021 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04882284 0,12192478 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04882284 0,12175979 ! response to X-ray GO:0010165 7 7 0,000 0,04882284 0,12159525 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04882284 0,12143116 ! UV protection GO:0009650 7 7 0,000 0,04882284 0,1212675 ! DNA integration GO:0015074 7 7 0,000 0,04882284 0,12110429 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04882284 0,12094152 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04882284 0,12077918 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04882284 0,12061728 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04882284 0,12045581 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04882284 0,12029477 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04882284 0,12013416 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04882284 0,11997398 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04882284 0,11981423 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04882284 0,1196549 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04882284 0,119496 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04882284 0,11933752 ! eating behavior GO:0042755 7 7 0,000 0,04882284 0,11917945 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04882284 0,11902181 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04882284 0,11886458 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04882284 0,11870777 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04882284 0,11855137 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04882284 0,11839538 ! cranial nerve development GO:0021545 7 7 0,000 0,04882284 0,1182398 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04882284 0,11808463 ! induction of an organ GO:0001759 7 7 0,000 0,04882284 0,11792987 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04882284 0,11777551 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04882284 0,11762155 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04882284 0,117468 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04882284 0,11731485 ! platelet activation GO:0030168 8 7 0,000 0,04882284 0,11716209 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04882284 0,11700974 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04882284 0,11685778 ! natural killer cell activation GO:0030101 7 7 0,000 0,04882284 0,11670621 ! NADP metabolic process GO:0006739 7 7 0,000 0,04882284 0,11655504 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04882284 0,11640425 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04882284 0,11625386 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04882284 0,11610386 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04882284 0,11595424 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04882284 0,115805 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04882284 0,11565615 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04882284 0,11550769 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04882284 0,1153596 ! cell-cell recognition GO:0009988 8 7 0,000 0,04882284 0,11521189 ! hormone catabolic process GO:0042447 7 7 0,000 0,04882284 0,11506456 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04882284 0,11491761 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04882284 0,11477103 ! oxygen transport GO:0015671 7 7 0,000 0,04882284 0,11462483 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04882284 0,11447899 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04882284 0,11433353 ! cell killing GO:0001906 7 7 0,000 0,04882284 0,11418844 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04882284 0,11404371 ! adult feeding behavior GO:0008343 7 7 0,000 0,04882284 0,11389935 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04882284 0,11375536 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04882284 0,11361173 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04882284 0,11346846 ! response to cold GO:0009409 7 7 0,000 0,04882284 0,11332555 ! negative regulation of transport GO:0051051 51 50 1,000 0,04901646 0,11363187 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,04901646 0,11348912 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,04901646 0,11334672 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,04901646 0,11320469 ! rRNA metabolic process GO:0016072 51 51 1,000 0,0507901 0,11715412 GO:0006364|rRNA processing, ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,0507901 0,11700768 GO:0051325|interphase, ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,05258675 0,12099548 ! response to light stimulus GO:0009416 53 52 1,000 0,05258675 0,12084461 ! tRNA metabolic process GO:0006399 53 53 1,000 0,05440602 0,12486962 ! regulation of T cell activation GO:0050863 53 53 1,000 0,05440602 0,12471431 ! regulation of protein transport GO:0051223 53 53 1,000 0,05440602 0,12455938 GO:0070201|regulation of establishment of protein localization, ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05560411 0,12714438 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05560411 0,12698683 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05560411 0,12682967 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05560411 0,12667289 ! superoxide anion generation GO:0042554 8 8 0,000 0,05560411 0,12651651 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05560411 0,12636051 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05560411 0,12620489 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05560411 0,12604966 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05560411 0,12589481 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05560411 0,12574033 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05560411 0,12558624 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05560411 0,12543252 ! zinc ion transport GO:0006829 8 8 0,000 0,05560411 0,12527918 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05560411 0,12512622 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05560411 0,12497362 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05560411 0,1248214 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05560411 0,12466955 ! response to pain GO:0048265 8 8 0,000 0,05560411 0,12451807 ! response to cAMP GO:0051591 8 8 0,000 0,05560411 0,12436696 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05560411 0,12421621 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05560411 0,12406583 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05560411 0,12391581 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05560411 0,12376615 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05560411 0,12361685 GO:0032107|regulation of response to nutrient levels, ! sensory perception of taste GO:0050909 8 8 0,000 0,05560411 0,12346792 ! organelle fusion GO:0048284 8 8 0,000 0,05560411 0,12331934 ! pancreas development GO:0031016 8 8 0,000 0,05560411 0,12317112 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05560411 0,12302326 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05560411 0,12287575 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05560411 0,12272859 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05560411 0,12258178 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05560411 0,12243533 ! sperm motility GO:0030317 8 8 0,000 0,05560411 0,12228923 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05560411 0,12214347 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05560411 0,12199806 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05560411 0,121853 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05560411 0,12170828 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05560411 0,1215639 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05560411 0,12141987 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05560411 0,12127618 ! Golgi organization GO:0007030 8 8 0,000 0,05560411 0,12113283 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05560411 0,12098981 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05560411 0,12084714 ! fructose metabolic process GO:0006000 8 8 0,000 0,05560411 0,1207048 ! mannose metabolic process GO:0006013 9 8 0,000 0,05560411 0,12056279 ! NAD metabolic process GO:0019674 8 8 0,000 0,05560411 0,12042112 ! sex determination GO:0007530 8 8 0,000 0,05560411 0,12027978 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05560411 0,12013877 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05560411 0,11999809 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,05560411 0,11985774 ! response to fungus GO:0009620 8 8 0,000 0,05560411 0,11971772 ! stem cell differentiation GO:0048863 8 8 0,000 0,05560411 0,11957803 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05560411 0,11943866 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05560411 0,11929962 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05560411 0,1191609 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05560411 0,1190225 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05560411 0,11888442 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05560411 0,11874666 ! vasoconstriction GO:0042310 8 8 0,000 0,05560411 0,11860923 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05560411 0,11847211 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05560411 0,1183353 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05560411 0,11819881 ! sensory perception of pain GO:0019233 8 8 0,000 0,05560411 0,11806264 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05560411 0,11792678 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05560411 0,11779123 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05560411 0,117656 ! chromatin silencing GO:0006342 8 8 0,000 0,05560411 0,11752107 ! tissue regeneration GO:0042246 8 8 0,000 0,05560411 0,11738645 ! salivary gland development GO:0007431 8 8 0,000 0,05560411 0,11725214 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05560411 0,11711814 ! T cell homeostasis GO:0043029 8 8 0,000 0,05560411 0,11698444 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05560411 0,11685105 ! water homeostasis GO:0030104 8 8 0,000 0,05560411 0,11671796 ! cofactor transport GO:0051181 8 8 0,000 0,05560411 0,11658518 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05560411 0,1164527 ! acid secretion GO:0046717 8 8 0,000 0,05560411 0,11632051 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05560411 0,11618863 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05560411 0,11605705 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05560411 0,11592576 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05560411 0,11579477 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05560411 0,11566408 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05560411 0,11553368 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05560411 0,11540357 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05560411 0,11527376 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05560411 0,11514424 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05560411 0,11501501 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05560411 0,11488607 ! developmental induction GO:0031128 8 8 0,000 0,05560411 0,11475742 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05560411 0,11462905 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05560411 0,11450097 ! actin filament polymerization GO:0030041 9 8 0,000 0,05560411 0,11437318 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05560411 0,11424568 ! peptide hormone processing GO:0016486 8 8 0,000 0,05560411 0,11411845 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05560411 0,11399151 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05560411 0,11386486 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05811084 0,11886601 ! extracellular structure organization GO:0043062 56 56 1,000 0,0599956 0,12258524 ! regulation of nervous system development GO:0051960 57 56 1,000 0,0599956 0,12244948 ! regulation of binding GO:0051098 60 57 1,000 0,06190141 0,12619944 ! regulation of protein localization GO:0032880 58 57 1,000 0,06190141 0,12605999 ! lactation GO:0007595 10 9 0,000 0,06233801 0,12680901 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06233801 0,12666919 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06233801 0,12652969 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06233801 0,12639049 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06233801 0,1262516 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06233801 0,12611302 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06233801 0,12597474 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,06233801 0,12583676 ! viral genome replication GO:0019079 9 9 0,000 0,06233801 0,12569908 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06233801 0,1255617 ! copper ion transport GO:0006825 9 9 0,000 0,06233801 0,12542463 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06233801 0,12528785 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06233801 0,12515137 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06233801 0,12501519 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06233801 0,1248793 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06233801 0,12474371 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06233801 0,12460842 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06233801 0,12447341 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06233801 0,1243387 ! phospholipid efflux GO:0033700 9 9 0,000 0,06233801 0,12420428 ! response to alkaloid GO:0043279 10 9 0,000 0,06233801 0,12407015 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06233801 0,12393631 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06233801 0,12380276 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06233801 0,12366949 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06233801 0,12353652 ! response to ethanol GO:0045471 9 9 0,000 0,06233801 0,12340382 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06233801 0,12327142 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06233801 0,12313929 ! methionine metabolic process GO:0006555 9 9 0,000 0,06233801 0,12300745 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06233801 0,12287589 ! cerebral cortex development GO:0021987 9 9 0,000 0,06233801 0,12274461 ! response to osmotic stress GO:0006970 9 9 0,000 0,06233801 0,12261362 ! pigmentation during development GO:0048066 9 9 0,000 0,06233801 0,1224829 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06233801 0,12235246 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06233801 0,1222223 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06233801 0,12209241 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06233801 0,1219628 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06233801 0,12183347 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06233801 0,12170441 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06233801 0,12157562 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06233801 0,1214471 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,06233801 0,12131886 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06233801 0,12119089 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06233801 0,12106318 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06233801 0,12093575 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06233801 0,12080858 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06233801 0,12068168 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06233801 0,12055505 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,06233801 0,12042868 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,06233801 0,12030258 ! DNA replication initiation GO:0006270 9 9 0,000 0,06233801 0,12017674 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06233801 0,12005116 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06233801 0,11992585 ! regulation of cellular pH GO:0030641 9 9 0,000 0,06233801 0,11980079 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06233801 0,119676 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06233801 0,11955147 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06233801 0,11942719 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06233801 0,11930318 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06233801 0,11917942 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06233801 0,11905592 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06233801 0,11893267 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06233801 0,11880968 ! collagen catabolic process GO:0030574 9 9 0,000 0,06233801 0,11868694 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06233801 0,11856446 ! purine base metabolic process GO:0006144 9 9 0,000 0,06233801 0,11844223 ! gas transport GO:0015669 9 9 0,000 0,06233801 0,11832025 ! cholesterol efflux GO:0033344 9 9 0,000 0,06233801 0,11819852 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06233801 0,11807704 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06233801 0,11795581 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06233801 0,11783483 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06233801 0,1177141 ! defense response to virus GO:0051607 9 9 0,000 0,06233801 0,11759361 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06233801 0,11747337 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06233801 0,11735338 ! regulation of cell development GO:0060284 60 59 1,000 0,06577465 0,12369662 ! protein polymerization GO:0051258 65 60 1,000 0,06774134 0,12726534 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06902488 0,12954465 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06902488 0,12941287 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06902488 0,12928135 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06902488 0,1291501 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,06902488 0,12901912 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06902488 0,1288884 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06902488 0,12875794 ! neuron maturation GO:0042551 10 10 0,000 0,06902488 0,12862775 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06902488 0,12849783 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06902488 0,12836816 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06902488 0,12823876 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06902488 0,12810962 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06902488 0,12798073 ! hormone secretion GO:0046879 10 10 0,000 0,06902488 0,12785211 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06902488 0,12772374 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06902488 0,12759564 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,06902488 0,12746778 ! inositol metabolic process GO:0006020 10 10 0,000 0,06902488 0,12734019 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06902488 0,12721285 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06902488 0,12708576 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06902488 0,12695893 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06902488 0,12683235 ! glial cell development GO:0021782 10 10 0,000 0,06902488 0,12670602 ! phototransduction GO:0007602 11 10 0,000 0,06902488 0,12657995 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,06902488 0,12645412 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06902488 0,12632855 ! fat cell differentiation GO:0045444 10 10 0,000 0,06902488 0,12620322 ! myoblast differentiation GO:0045445 10 10 0,000 0,06902488 0,12607815 ! centrosome cycle GO:0007098 10 10 0,000 0,06902488 0,12595332 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06902488 0,12582873 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06902488 0,1257044 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06902488 0,1255803 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06902488 0,12545646 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06902488 0,12533286 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06902488 0,1252095 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06902488 0,12508638 ! plasma membrane organization GO:0007009 10 10 0,000 0,06902488 0,12496351 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06902488 0,12484087 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,06902488 0,12471848 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06902488 0,12459633 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06902488 0,12447441 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06902488 0,12435274 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06902488 0,1242313 ! exocrine system development GO:0035272 10 10 0,000 0,06902488 0,1241101 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06902488 0,12398913 ! embryo implantation GO:0007566 11 10 0,000 0,06902488 0,1238684 ! regulation of protein binding GO:0043393 11 10 0,000 0,06902488 0,12374791 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06902488 0,12362765 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06902488 0,12350762 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06902488 0,12338783 ! protein export from nucleus GO:0006611 10 10 0,000 0,06902488 0,12326826 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06902488 0,12314893 ! cytolysis GO:0019835 10 10 0,000 0,06902488 0,12302983 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06902488 0,12291096 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06902488 0,12279232 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06902488 0,12267391 ! histone deacetylation GO:0016575 10 10 0,000 0,06902488 0,12255573 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06902488 0,12243778 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06902488 0,12232005 ! gland morphogenesis GO:0022612 10 10 0,000 0,06902488 0,12220254 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06902488 0,12208527 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06902488 0,12196822 GO:0046467|membrane lipid biosynthetic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06902488 0,12185139 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06902488 0,12173478 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06902488 0,1216184 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06902488 0,12150224 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06902488 0,12138631 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06902488 0,12127059 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06902488 0,12115509 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06902488 0,12103982 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06902488 0,12092476 ! nerve development GO:0021675 10 10 0,000 0,06902488 0,12080992 ! gut development GO:0048565 10 10 0,000 0,06902488 0,1206953 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06902488 0,1205809 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,06902488 0,12046671 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06902488 0,12035274 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06902488 0,12023899 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06902488 0,12012545 ! protein stabilization GO:0050821 10 10 0,000 0,06902488 0,12001212 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,06972759 0,12111964 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,06972759 0,12100559 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,06972759 0,12089176 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,07173301 0,12425182 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,07173301 0,12413516 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,07173301 0,12401871 ! protein secretion GO:0009306 11 11 0,000 0,07566502 0,13069413 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07566502 0,13057175 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07566502 0,13044961 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07566502 0,13032769 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07566502 0,13020601 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07566502 0,13008454 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07566502 0,12996331 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07566502 0,1298423 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07566502 0,12972152 ! skin development GO:0043588 11 11 0,000 0,07566502 0,12960096 ! signal complex assembly GO:0007172 11 11 0,000 0,07566502 0,12948062 ! endothelial cell migration GO:0043542 11 11 0,000 0,07566502 0,12936051 ! peroxisomal transport GO:0043574 11 11 0,000 0,07566502 0,12924062 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07566502 0,12912096 GO:0008213|protein amino acid alkylation, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07566502 0,12900151 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 0,000 0,07566502 0,12888228 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07566502 0,12876328 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07566502 0,12864449 ! spinal cord development GO:0021510 11 11 0,000 0,07566502 0,12852593 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07566502 0,12840758 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07566502 0,12828945 ! cellular response to starvation GO:0009267 11 11 0,000 0,07566502 0,12817154 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07566502 0,12805384 ! digestive system process GO:0022600 11 11 0,000 0,07566502 0,12793636 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07566502 0,12781909 ! fucose metabolic process GO:0006004 11 11 0,000 0,07566502 0,12770204 ! membrane budding GO:0006900 11 11 0,000 0,07566502 0,12758521 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,07566502 0,12746858 ! monoamine transport GO:0015844 11 11 0,000 0,07566502 0,12735218 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07566502 0,12723598 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07566502 0,12711999 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07566502 0,12700422 ! body fluid secretion GO:0007589 11 11 0,000 0,07566502 0,12688865 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,07566502 0,1267733 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07566502 0,12665816 ! interaction with host GO:0051701 11 11 0,000 0,07566502 0,12654322 ! membrane depolarization GO:0051899 11 11 0,000 0,07566502 0,1264285 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07566502 0,12631398 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07566502 0,12619967 ! oogenesis GO:0048477 11 11 0,000 0,07566502 0,12608556 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07566502 0,12597166 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,07566502 0,12585797 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,07566502 0,12574448 ! muscle maintenance GO:0046716 12 11 0,000 0,07566502 0,1256312 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07566502 0,12551812 ! hindbrain development GO:0030902 11 11 0,000 0,07566502 0,12540524 ! steroid catabolic process GO:0006706 11 11 0,000 0,07566502 0,12529257 ! endocrine process GO:0050886 11 11 0,000 0,07566502 0,1251801 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07566502 0,12506783 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07566502 0,12495576 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07566502 0,1248439 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07566502 0,12473223 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,07579998 0,12484305 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,07579998 0,12473158 ! anion transport GO:0006820 65 65 1,000 0,07786082 0,12800846 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,08203544 0,13475161 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,08225876 0,13499813 ! translational initiation GO:0006413 12 12 0,000 0,08225876 0,13487802 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08225876 0,13475813 ! initiation of viral infection GO:0019059 12 12 0,000 0,08225876 0,13463845 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,08225876 0,13451899 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08225876 0,13439973 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08225876 0,13428069 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08225876 0,13416186 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08225876 0,13404323 ! collagen metabolic process GO:0032963 12 12 0,000 0,08225876 0,13392482 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08225876 0,13380662 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08225876 0,13368862 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08225876 0,13357084 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08225876 0,13345326 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08225876 0,13333588 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08225876 0,13321872 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08225876 0,13310175 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08225876 0,132985 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,08225876 0,13286845 ! retinoid metabolic process GO:0001523 12 12 0,000 0,08225876 0,1327521 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08225876 0,13263596 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08225876 0,13252002 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08225876 0,13240428 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08225876 0,13228874 ! acute-phase response GO:0006953 12 12 0,000 0,08225876 0,13217341 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08225876 0,13205827 ! vacuolar transport GO:0007034 12 12 0,000 0,08225876 0,13194334 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08225876 0,13182861 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08225876 0,13171407 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08225876 0,13159974 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08225876 0,1314856 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08225876 0,13137166 ! male gonad development GO:0008584 12 12 0,000 0,08225876 0,13125792 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08225876 0,13114438 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08225876 0,13103103 ! renal system process GO:0003014 12 12 0,000 0,08225876 0,13091787 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08225876 0,13080492 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08225876 0,13069215 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08225876 0,13057959 ! pallium development GO:0021543 13 12 0,000 0,08225876 0,13046721 ! cell fate determination GO:0001709 12 12 0,000 0,08225876 0,13035503 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,08225876 0,13024304 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08225876 0,13013124 ! G1 phase GO:0051318 13 12 0,000 0,08225876 0,13001964 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08225876 0,12990822 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08225876 0,129797 ! detection of light stimulus GO:0009583 13 12 0,000 0,08225876 0,12968597 ! synaptogenesis GO:0007416 12 12 0,000 0,08225876 0,12957513 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08225876 0,12946447 ! hormone transport GO:0009914 12 12 0,000 0,08225876 0,12935401 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08225876 0,12924373 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08225876 0,12913364 ! spermatid differentiation GO:0048515 13 12 0,000 0,08225876 0,12902374 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08225876 0,12891403 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08225876 0,1288045 ! neural tube closure GO:0001843 13 12 0,000 0,08225876 0,12869516 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,08225876 0,128586 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,08225876 0,12847703 ! regulation of cell size GO:0008361 68 68 1,000 0,08414854 0,13131732 ! sensory perception of sound GO:0007605 71 69 1,000 0,08627838 0,13452712 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,08627838 0,1344134 ! positive regulation of transport GO:0051050 71 70 1,000 0,08842463 0,1376407 ! growth GO:0040007 70 70 1,000 0,08842463 0,13752455 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,08842463 0,13740859 GO:0016053|organic acid biosynthetic process, ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,08880642 0,13788562 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08880642 0,13776956 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08880642 0,13765369 ! phenol metabolic process GO:0018958 13 13 0,000 0,08880642 0,13753801 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,08880642 0,13742253 ! gluconeogenesis GO:0006094 13 13 0,000 0,08880642 0,13730724 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08880642 0,13719215 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08880642 0,13707725 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08880642 0,13696254 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08880642 0,13684802 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08880642 0,1367337 ! regeneration GO:0031099 13 13 0,000 0,08880642 0,13661956 ! keratinization GO:0031424 13 13 0,000 0,08880642 0,13650562 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08880642 0,13639186 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08880642 0,1362783 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,08880642 0,13616492 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,08880642 0,13605173 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08880642 0,13593873 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,08880642 0,13582592 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08880642 0,13571329 ! autophagy GO:0006914 13 13 0,000 0,08880642 0,13560086 ! receptor metabolic process GO:0043112 14 13 0,000 0,08880642 0,1354886 ! actin filament bundle formation GO:0051017 13 13 0,000 0,08880642 0,13537654 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,08880642 0,13526466 ! ureteric bud development GO:0001657 13 13 0,000 0,08880642 0,13515296 ! cell aging GO:0007569 13 13 0,000 0,08880642 0,13504145 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,08880642 0,13493012 ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08880642 0,13481897 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08880642 0,13470801 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08880642 0,13459723 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,08880642 0,13448663 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08880642 0,13437622 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08880642 0,13426598 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08880642 0,13415593 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08880642 0,13404606 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08880642 0,13393636 ! neural crest cell migration GO:0001755 14 13 0,000 0,08880642 0,13382685 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08880642 0,13371751 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08880642 0,13360835 ! immunoglobulin production GO:0002377 13 13 0,000 0,08880642 0,13349937 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08880642 0,13339057 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,08880642 0,13328195 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08880642 0,1331735 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08880642 0,13306523 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08880642 0,13295714 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08880642 0,13284922 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08880642 0,13274147 ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08880642 0,1326339 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08880642 0,1325265 GO:0033014|tetrapyrrole biosynthetic process, ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08880642 0,13241928 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08880642 0,13231223 ! blastocyst development GO:0001824 13 13 0,000 0,08880642 0,13220536 ! telomere organization GO:0032200 13 13 0,000 0,08880642 0,13209865 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08880642 0,13199212 ! regulation of amine transport GO:0051952 13 13 0,000 0,08880642 0,13188576 ! tissue homeostasis GO:0001894 13 13 0,000 0,08880642 0,13177958 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08880642 0,13167356 ! protein tetramerization GO:0051262 13 13 0,000 0,08880642 0,13156771 ! ribosome biogenesis GO:0042254 71 71 1,000 0,09058696 0,1340978 ! secretion by cell GO:0032940 75 72 1,000 0,09276503 0,13721184 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,09276503 0,13710181 ! regulation of cytokine production GO:0001817 72 72 1,000 0,09276503 0,13699195 ! neuron fate commitment GO:0048663 14 14 0,000 0,09530831 0,14063508 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09530831 0,14052257 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09530831 0,14041025 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09530831 0,1402981 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09530831 0,14018613 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09530831 0,14007434 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09530831 0,13996272 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09530831 0,13985129 ! vesicle docking GO:0048278 14 14 0,000 0,09530831 0,13974003 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09530831 0,13962895 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09530831 0,13951804 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09530831 0,13940732 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09530831 0,13929676 ! hair cycle GO:0042633 14 14 0,000 0,09530831 0,13918639 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09530831 0,13907618 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09530831 0,13896615 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09530831 0,1388563 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,09530831 0,13874662 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09530831 0,13863711 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09530831 0,13852777 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,09530831 0,13841861 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,09530831 0,13830962 ! primary neural tube formation GO:0014020 15 14 0,000 0,09530831 0,1382008 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09530831 0,13809215 ! base-excision repair GO:0006284 14 14 0,000 0,09530831 0,13798368 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,09530831 0,13787537 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09530831 0,13776723 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09530831 0,13765926 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,09530831 0,13755146 ! collagen fibril organization GO:0030199 14 14 0,000 0,09530831 0,13744383 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09530831 0,13733637 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,09530831 0,13722908 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09530831 0,13712195 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09530831 0,13701499 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09530831 0,1369082 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09530831 0,13680157 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09530831 0,13669511 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,10162846 0,14564639 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,10176475 0,14572838 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,10176475 0,14561524 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10176475 0,14550227 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10176475 0,14538948 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,10176475 0,14527686 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10176475 0,14516442 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10176475 0,14505215 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10176475 0,14494005 ! response to vitamin GO:0033273 15 15 0,000 0,10176475 0,14482813 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,10176475 0,14471638 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10176475 0,1446048 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10176475 0,1444934 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,10176475 0,14438216 ! ovarian follicle development GO:0001541 15 15 0,000 0,10176475 0,1442711 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10176475 0,14416021 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10176475 0,14404949 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10176475 0,14393893 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10176475 0,14382855 ! heme metabolic process GO:0042168 15 15 0,000 0,10176475 0,14371834 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10176475 0,14360829 ! chromosome condensation GO:0030261 15 15 0,000 0,10176475 0,14349842 ! response to starvation GO:0042594 15 15 0,000 0,10176475 0,14338871 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10176475 0,14327917 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10176475 0,14316979 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10176475 0,14306059 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,10176475 0,14295155 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10176475 0,14284267 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10176475 0,14273397 ! phospholipid transport GO:0015914 15 15 0,000 0,10176475 0,14262542 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,10176475 0,14251704 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10176475 0,14240883 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10176475 0,14230078 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10176475 0,1421929 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,10176475 0,14208517 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,10176475 0,14197762 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10176475 0,14187022 ! protein homooligomerization GO:0051260 15 15 0,000 0,10176475 0,14176299 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10176475 0,14165591 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,10614647 0,14764373 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,10817604 0,15035328 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,10817604 0,15023997 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10817604 0,15012684 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,10817604 0,15001388 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10817604 0,14990109 ! learning GO:0007612 16 16 0,000 0,10817604 0,14978846 ! circadian rhythm GO:0007623 16 16 0,000 0,10817604 0,14967601 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10817604 0,14956372 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,10817604 0,14945161 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,10817604 0,14933966 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10817604 0,14922788 ! vesicle targeting GO:0006903 17 16 0,000 0,10817604 0,14911626 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10817604 0,14900482 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,10817604 0,14889354 ! positive regulation of cell development GO:0010720 16 16 0,000 0,10817604 0,14878242 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,10817604 0,14867147 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,10817604 0,14856069 ! cell fate specification GO:0001708 16 16 0,000 0,10817604 0,14845007 ! pentose metabolic process GO:0019321 16 16 0,000 0,10817604 0,14833962 ! fatty acid transport GO:0015908 16 16 0,000 0,10817604 0,14822933 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10817604 0,1481192 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,10817604 0,14800924 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10817604 0,14789944 ! polyol metabolic process GO:0019751 16 16 0,000 0,10817604 0,1477898 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10817604 0,14768033 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10817604 0,14757102 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10817604 0,14746187 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10817604 0,14735288 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,10817604 0,14724405 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,10817604 0,14713538 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,10817604 0,14702688 ! MAPKKK cascade GO:0000165 82 81 1,000 0,11302449 0,15350341 ! lipid catabolic process GO:0016042 82 81 1,000 0,11302449 0,15339038 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,1145425 0,15533615 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,1145425 0,15522193 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,1145425 0,15510788 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,1145425 0,154994 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,1145425 0,15488028 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,1145425 0,15476674 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,1145425 0,15465335 ! sensory perception of smell GO:0007608 17 17 0,000 0,1145425 0,15454014 ! glucose transport GO:0015758 17 17 0,000 0,1145425 0,15442709 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,1145425 0,1543142 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,1145425 0,15420148 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,1145425 0,15408893 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,1145425 0,15397653 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,1145425 0,15386431 ! neural crest cell development GO:0014032 19 17 0,000 0,1145425 0,15375224 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,1145425 0,15364034 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,1145425 0,1535286 GO:0002764|immune response-regulating signal transduction, ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,1145425 0,15341703 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,1145425 0,15330561 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,1145425 0,15319436 ! pigmentation GO:0043473 17 17 0,000 0,1145425 0,15308327 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,1145425 0,15297234 ! embryonic organ development GO:0048568 17 17 0,000 0,1145425 0,15286157 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,1145425 0,15275096 ! liver development GO:0001889 17 17 0,000 0,1145425 0,15264051 ! gene silencing GO:0016458 17 17 0,000 0,1145425 0,15253022 ! ncRNA processing GO:0034470 83 83 1,000 0,11767375 0,1565868 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12086443 0,16071656 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,12086443 0,16060068 ! meiosis I GO:0007127 18 18 0,000 0,12086443 0,16048498 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12086443 0,16036944 ! membrane docking GO:0022406 18 18 0,000 0,12086443 0,16025406 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,12086443 0,16013886 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,12086443 0,16002381 GO:0070661|leukocyte proliferation, ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12086443 0,15990894 ! hexose transport GO:0008645 18 18 0,000 0,12086443 0,15979422 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,12086443 0,15967968 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,12086443 0,15956529 ! striated muscle contraction GO:0006941 18 18 0,000 0,12086443 0,15945107 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12086443 0,15933702 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,12086443 0,15922312 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,12086443 0,15910939 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,12086443 0,15899582 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12086443 0,15888242 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12086443 0,15876917 ! B cell differentiation GO:0030183 18 18 0,000 0,12086443 0,15865609 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,12086443 0,15854317 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,12086443 0,1584304 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,12086443 0,1583178 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12086443 0,15820536 ! regulation of cellular localization GO:0060341 86 85 1,000 0,12237145 0,16006429 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,12714214 0,1661865 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,12714214 0,16606872 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,12714214 0,16595111 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,12714214 0,16583366 ! glial cell differentiation GO:0010001 19 19 0,000 0,12714214 0,16571638 ! regulation of pH GO:0006885 19 19 0,000 0,12714214 0,16559927 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,12714214 0,16548232 ! feeding behavior GO:0007631 19 19 0,000 0,12714214 0,16536554 ! peroxisome organization GO:0007031 19 19 0,000 0,12714214 0,16524892 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,12714214 0,16513246 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,12714214 0,16501617 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,12714214 0,16490005 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,12714214 0,16478408 ! metanephros development GO:0001656 19 19 0,000 0,12714214 0,16466828 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,12714214 0,16455265 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,12714214 0,16443717 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,12714214 0,16432186 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,12714214 0,1642067 ! regulation of protein stability GO:0031647 19 19 0,000 0,12714214 0,16409171 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,12714214 0,16397688 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,12714214 0,16386221 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,12714214 0,16374771 ! eye morphogenesis GO:0048592 19 19 0,000 0,12714214 0,16363336 ! placenta development GO:0001890 19 19 0,000 0,12714214 0,16351917 ! vesicle localization GO:0051648 20 19 0,000 0,12714214 0,16340514 ! male gamete generation GO:0048232 90 88 1,000 0,12950396 0,1663246 GO:0007283|spermatogenesis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,1319033 0,16928815 ! regulation of muscle development GO:0048634 21 20 0,000 0,13337593 0,17105904 ! negative regulation of binding GO:0051100 21 20 0,000 0,13337593 0,17094009 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13337593 0,17082129 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,13337593 0,17070267 ! nucleus organization GO:0006997 20 20 0,000 0,13337593 0,17058421 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,13337593 0,17046591 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13337593 0,17034778 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13337593 0,17022981 ! chromatin remodeling GO:0006338 20 20 0,000 0,13337593 0,170112 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13337593 0,16999436 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,13337593 0,16987688 ! lipid oxidation GO:0034440 20 20 0,000 0,13337593 0,16975956 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,13337593 0,1696424 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13337593 0,16952541 ! single fertilization GO:0007338 21 20 0,000 0,13337593 0,16940858 ! regulation of B cell activation GO:0050864 20 20 0,000 0,13337593 0,1692919 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,13673312 0,17343368 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,13673312 0,1733144 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,13916309 0,17627324 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,1395661 0,17666231 ! mRNA catabolic process GO:0006402 21 21 0,000 0,1395661 0,17654106 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,1395661 0,17641998 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,1395661 0,17629906 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,1395661 0,17617831 ! Notch signaling pathway GO:0007219 22 21 0,000 0,1395661 0,17605772 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,1395661 0,1759373 ! ear morphogenesis GO:0042471 21 21 0,000 0,1395661 0,17581704 ! organic anion transport GO:0015711 21 21 0,000 0,1395661 0,17569695 ! cholesterol transport GO:0030301 21 21 0,000 0,1395661 0,17557702 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,1395661 0,17545725 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,1395661 0,17533765 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,1395661 0,17521821 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,1395661 0,17509893 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,1395661 0,17497982 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,1395661 0,17486086 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,1395661 0,17474207 ! regulation of proteolysis GO:0030162 21 21 0,000 0,1395661 0,17462344 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,1395661 0,17450497 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,1395661 0,17438666 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,1395661 0,17426852 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,1395661 0,17415053 ! tissue morphogenesis GO:0048729 94 93 1,000 0,14160274 0,1765723 ! regulation of response to stress GO:0080134 97 94 1,000 0,14405184 0,17950476 ! RNA export from nucleus GO:0006405 22 22 0,000 0,14571296 0,18145201 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,14571296 0,18132949 ! sister chromatid segregation GO:0000819 22 22 0,000 0,14571296 0,18120714 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,14571296 0,18108495 ! regulation of ion transport GO:0043269 22 22 0,000 0,14571296 0,18096292 ! odontogenesis GO:0042476 22 22 0,000 0,14571296 0,18084106 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,14571296 0,18071937 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,14571296 0,18059783 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,14571296 0,18047646 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,14571296 0,18035526 ! ovulation cycle process GO:0022602 22 22 0,000 0,14571296 0,18023421 ! spindle organization GO:0007051 22 22 0,000 0,14571296 0,18011333 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,14571296 0,17999261 ! cell chemotaxis GO:0060326 23 22 0,000 0,14571296 0,17987206 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,14571296 0,17975166 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,14571296 0,17963142 ! male sex differentiation GO:0046661 22 22 0,000 0,14571296 0,17951135 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,14571296 0,17939144 ! biopolymer methylation GO:0043414 22 22 0,000 0,14571296 0,17927168 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,14571296 0,17915209 ! detection of external stimulus GO:0009581 23 22 0,000 0,14571296 0,17903265 ! neuron migration GO:0001764 22 22 0,000 0,14571296 0,17891338 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,14571296 0,17879426 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,14571296 0,1786753 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,14571296 0,1785565 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,14571296 0,17843786 ! cytokine production GO:0001816 22 22 0,000 0,14571296 0,17831937 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,14571296 0,17820105 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,15181679 0,18554266 ! viral infectious cycle GO:0019058 23 23 0,000 0,15181679 0,18541971 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,15181679 0,18529691 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,15181679 0,18517428 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,15181679 0,18505181 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,15181679 0,1849295 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,15181679 0,18480736 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,15181679 0,18468537 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,15181679 0,18456355 ! endocrine system development GO:0035270 23 23 0,000 0,15181679 0,18444188 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,15181679 0,18432038 ! positive regulation of growth GO:0045927 23 23 0,000 0,15181679 0,18419904 ! female gonad development GO:0008585 23 23 0,000 0,15181679 0,18407785 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,15181679 0,18395683 ! lipid homeostasis GO:0055088 23 23 0,000 0,15181679 0,18383596 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,15181679 0,18371526 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,15181679 0,18359471 ! endocytosis GO:0006897 99 98 1,000 0,15393767 0,18603746 GO:0010324|membrane invagination, ! mitochondrial transport GO:0006839 24 24 0,000 0,15787789 0,19067428 ! gliogenesis GO:0042063 24 24 0,000 0,15787789 0,19054941 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,15787789 0,1904247 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,15787789 0,19030016 ! glucose homeostasis GO:0042593 24 24 0,000 0,15787789 0,19017578 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,15787789 0,19005157 ! T cell differentiation GO:0030217 24 24 0,000 0,15787789 0,18992751 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,15787789 0,18980362 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,15787789 0,18967989 ! ovulation cycle GO:0042698 24 24 0,000 0,15787789 0,18955632 ! fertilization GO:0009566 25 24 0,000 0,15787789 0,18943291 ! maintenance of protein location GO:0045185 25 24 0,000 0,15787789 0,18930966 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,15787789 0,18918657 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,15787789 0,18906364 ! response to hormone stimulus GO:0009725 102 100 1,000 0,15893085 0,19020101 ! response to other organism GO:0051707 101 100 1,000 0,15893085 0,19007758 ! hemopoiesis GO:0030097 104 100 1,000 0,15893085 0,18995432 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,16389656 0,19576238 ! negative regulation of secretion GO:0051048 26 25 0,000 0,16389656 0,19563559 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,16389656 0,19550897 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,16389656 0,1953825 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,16389656 0,19525621 ! cellular component disassembly GO:0022411 26 25 0,000 0,16389656 0,19513007 ! endosome transport GO:0016197 25 25 0,000 0,16389656 0,1950041 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,16389656 0,19487829 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,16389656 0,19475264 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,16389656 0,19462716 ! excretion GO:0007588 25 25 0,000 0,16389656 0,19450184 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,16389656 0,19437667 ! gastrulation GO:0007369 25 25 0,000 0,16389656 0,19425167 ! regulation of endocytosis GO:0030100 25 25 0,000 0,16389656 0,19412683 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,16389656 0,19400215 ! positive regulation of defense response GO:0031349 26 26 0,000 0,16987308 0,20094742 ! glycolysis GO:0006096 26 26 0,000 0,16987308 0,20081853 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,16987308 0,2006898 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,16987308 0,20056123 ! cellular defense response GO:0006968 26 26 0,000 0,16987308 0,20043283 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,16987308 0,2003046 ! regulation of protein secretion GO:0050708 26 26 0,000 0,16987308 0,20017652 ! germ cell development GO:0007281 27 26 0,000 0,16987308 0,20004862 ! pigment metabolic process GO:0042440 26 26 0,000 0,16987308 0,19992087 ! response to insulin stimulus GO:0032868 28 26 0,000 0,16987308 0,19979329 ! maintenance of location in cell GO:0051651 27 26 0,000 0,16987308 0,19966587 ! chloride transport GO:0006821 27 27 0,000 0,17580775 0,20650967 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,17580775 0,20637814 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,17580775 0,20624677 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,17580775 0,20611557 ! activation of caspase activity GO:0006919 27 27 0,000 0,17580775 0,20598454 ! inner ear development GO:0048839 27 27 0,000 0,17580775 0,20585367 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,17580775 0,20572297 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,17580775 0,20559244 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,18170085 0,21234918 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 0,000 0,18170085 0,21221462 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,18170085 0,21208022 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,18170085 0,21194599 ! developmental growth GO:0048589 28 28 0,000 0,18170085 0,21181193 ! cartilage development GO:0051216 29 28 0,000 0,18170085 0,21167804 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,18755267 0,21835727 ! viral reproductive process GO:0022415 29 29 0,000 0,18755267 0,21821942 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,18755267 0,21808174 ! leukocyte migration GO:0050900 30 29 0,000 0,18755267 0,21794424 ! antigen processing and presentation GO:0019882 29 29 0,000 0,18755267 0,21780691 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,18755267 0,21766975 ! tRNA processing GO:0008033 29 29 0,000 0,18755267 0,21753277 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,18755267 0,21739595 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,18755267 0,21725931 ! RNA catabolic process GO:0006401 30 30 0,000 0,19336349 0,22384981 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,19336349 0,22370929 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,19336349 0,22356895 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,19336349 0,22342878 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,19336349 0,22328879 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,19336349 0,22314897 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,19336349 0,22300933 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,19336349 0,22286986 ! regulation of ossification GO:0030278 30 30 0,000 0,19336349 0,22273056 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,19336349 0,22259145 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,19336349 0,2224525 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,19336349 0,22231373 ! vesicle organization GO:0016050 30 30 0,000 0,19336349 0,22217513 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,19336349 0,2220367 ! establishment of organelle localization GO:0051656 31 30 0,000 0,19336349 0,22189845 ! membrane fusion GO:0006944 31 31 0,000 0,19913359 0,22837785 ! B cell activation GO:0042113 31 31 0,000 0,19913359 0,22823582 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,19913359 0,22809397 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,19913359 0,2279523 ! ion transmembrane transport GO:0034220 31 31 0,000 0,19913359 0,2278108 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,19913359 0,22766948 ! digestion GO:0007586 31 31 0,000 0,19913359 0,22752833 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,19913359 0,22738736 ! regulation of DNA replication GO:0006275 32 31 0,000 0,19913359 0,22724656 ! regulation of heart contraction GO:0008016 31 31 0,000 0,19913359 0,22710594 ! camera-type eye development GO:0043010 31 31 0,000 0,19913359 0,22696549 ! extracellular matrix organization GO:0030198 31 31 0,000 0,19913359 0,22682522 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,19913359 0,22668511 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,19913359 0,22654518 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,20486325 0,23291978 ! glucose catabolic process GO:0006007 32 32 0,000 0,20486325 0,23277618 ! lipid modification GO:0030258 32 32 0,000 0,20486325 0,23263276 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,20486325 0,23248951 ! cell maturation GO:0048469 32 32 0,000 0,20486325 0,23234644 ! nuclear export GO:0051168 32 32 0,000 0,20486325 0,23220355 ! kidney development GO:0001822 32 32 0,000 0,20486325 0,23206083 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,20486325 0,23191828 ! maintenance of location GO:0051235 33 32 0,000 0,20486325 0,23177592 ! negative regulation of cell size GO:0045792 33 33 0,000 0,21055275 0,2380667 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,21055275 0,23792073 ! amino acid transport GO:0006865 33 33 0,000 0,21055275 0,23777495 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,21055275 0,23762934 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,21055275 0,23748391 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,21055275 0,23733866 ! regulation of actin filament length GO:0030832 34 34 0,000 0,21620236 0,24355804 ! ear development GO:0043583 34 34 0,000 0,21620236 0,24340926 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,21620236 0,24326066 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,21620236 0,24311224 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,21620236 0,242964 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,21620236 0,24281594 ! secondary metabolic process GO:0019748 34 34 0,000 0,21620236 0,24266806 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,21620236 0,24252036 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,21620236 0,24237284 ! viral reproduction GO:0016032 34 34 0,000 0,21620236 0,24222551 ! acute inflammatory response GO:0002526 35 35 0,000 0,22181237 0,24835978 ! regulation of cellular component size GO:0032535 35 35 0,000 0,22181237 0,24820898 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,22181237 0,24805837 ! mesoderm development GO:0007498 35 35 0,000 0,22181237 0,24790794 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,22181237 0,24775769 GO:0048609|reproductive process in a multicellular organism, ! regulation of immune effector process GO:0002697 35 35 0,000 0,22181237 0,24760763 ! hydrogen transport GO:0006818 36 36 0,000 0,22738303 0,25367247 GO:0015992|proton transport, ! regulation of mitosis GO:0007088 37 36 0,000 0,22738303 0,25351901 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,22738303 0,25336574 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,22738303 0,25321264 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,22738303 0,25305974 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,22738303 0,25290702 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,22738303 0,25275448 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,22738303 0,25260213 ! gonad development GO:0008406 36 36 0,000 0,22738303 0,25244996 ! activation of immune response GO:0002253 36 36 0,000 0,22738303 0,25229797 ! coagulation GO:0050817 39 36 0,000 0,22738303 0,25214617 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,23291463 0,25812487 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,23291463 0,25796974 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,23291463 0,25781481 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,23291463 0,25766006 ! eye development GO:0001654 37 37 0,000 0,23291463 0,25750549 ! negative regulation of growth GO:0045926 37 37 0,000 0,23291463 0,25735111 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,23291463 0,25719692 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,23291463 0,25704291 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,23291463 0,25688908 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,23291463 0,25673544 ! positive regulation of secretion GO:0051047 39 38 0,000 0,23840742 0,26263292 ! neurotransmitter transport GO:0006836 40 38 0,000 0,23840742 0,26247603 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,23840742 0,26231933 ! chromosome segregation GO:0007059 38 38 0,000 0,23840742 0,26216281 ! urogenital system development GO:0001655 38 38 0,000 0,23840742 0,26200648 ! hexose catabolic process GO:0019320 38 38 0,000 0,23840742 0,26185034 ! RNA elongation GO:0006354 38 38 0,000 0,23840742 0,26169439 ! meiotic cell cycle GO:0051321 38 38 0,000 0,23840742 0,26153861 ! regulation of neurological system process GO:0031644 38 38 0,000 0,23840742 0,26138303 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,24386168 0,26720397 ! hemostasis GO:0007599 42 39 0,000 0,24386168 0,2670452 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,24386168 0,26688662 ! response to unfolded protein GO:0006986 39 39 0,000 0,24386168 0,26672823 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,24386168 0,26657003 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,24386168 0,26641202 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,24386168 0,26625419 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,24386168 0,26609655 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,24386168 0,2659391 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,24386168 0,26578183 ! developmental maturation GO:0021700 39 39 0,000 0,24386168 0,26562475 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,24386168 0,26546785 ! limb development GO:0060173 39 39 0,000 0,24386168 0,26531114 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,24386168 0,26515461 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,24927767 0,27088369 ! DNA catabolic process GO:0006308 41 40 0,000 0,24927767 0,27072406 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,24927767 0,27056463 ! organelle localization GO:0051640 41 40 0,000 0,24927767 0,27040538 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,25465565 0,27607668 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,25465565 0,27591438 ! amine catabolic process GO:0009310 42 41 0,000 0,25465565 0,27575227 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,25465565 0,27559035 ! regulation of caspase activity GO:0043281 41 41 0,000 0,25465565 0,27542861 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,25465565 0,27526707 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,25465565 0,27510572 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,25465565 0,27494456 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,25465565 0,27478358 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,25999588 0,28038175 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,25999588 0,28021779 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,25999588 0,28005401 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,25999588 0,27989043 ! protein ubiquitination GO:0016567 43 42 0,000 0,25999588 0,27972704 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,25999588 0,27956383 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,25999588 0,27940082 ! forebrain development GO:0030900 43 42 0,000 0,25999588 0,279238 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,25999588 0,27907537 ! reproductive structure development GO:0048608 43 43 0,000 0,26529863 0,2846015 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,26529863 0,28443594 ! alcohol catabolic process GO:0046164 43 43 0,000 0,26529863 0,28427057 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,26529863 0,28410539 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,26529863 0,28394041 ! mRNA transport GO:0051028 44 44 0,000 0,27056415 0,28940786 ! protein import into nucleus GO:0006606 44 44 0,000 0,27056415 0,28923999 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,27056415 0,28907231 ! vitamin metabolic process GO:0006766 44 44 0,000 0,27056415 0,28890483 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,27056415 0,28873754 ! amine biosynthetic process GO:0009309 46 45 0,000 0,2757927 0,29414696 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,2757927 0,29397684 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,2757927 0,29380691 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,2757927 0,29363718 ! nuclear import GO:0051170 45 45 0,000 0,2757927 0,29346764 ! protein processing GO:0016485 45 45 0,000 0,2757927 0,2932983 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,28098453 0,29864734 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,28098453 0,29847521 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,28098453 0,29830328 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,28098453 0,29813154 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,28098453 0,29796001 ! sex differentiation GO:0007548 47 47 0,000 0,2861399 0,30325235 ! amine transport GO:0015837 47 47 0,000 0,2861399 0,30307806 ! rhythmic process GO:0048511 47 47 0,000 0,2861399 0,30290398 ! regulation of catabolic process GO:0009894 48 47 0,000 0,2861399 0,3027301 ! calcium ion transport GO:0006816 48 48 0,000 0,29125905 0,30796926 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,29125905 0,30779267 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,29125905 0,30761629 ! protein localization in nucleus GO:0034504 48 48 0,000 0,29125905 0,3074401 ! DNA recombination GO:0006310 48 48 0,000 0,29125905 0,30726412 ! leukocyte differentiation GO:0002521 50 49 0,000 0,29634223 0,31244778 ! divalent metal ion transport GO:0070838 49 49 0,000 0,29634223 0,31226914 ! response to nutrient GO:0007584 49 49 0,000 0,29634223 0,3120907 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,29634223 0,31191247 ! regulation of defense response GO:0031347 50 50 0,000 0,30138969 0,31704407 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,30138969 0,31686321 ! chromatin assembly GO:0031497 50 50 0,000 0,30138969 0,31668256 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,30138969 0,31650211 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,30138969 0,31632187 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,30138969 0,31614184 ! transcription initiation GO:0006352 50 50 0,000 0,30138969 0,315962 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,30138969 0,31578238 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,30640168 0,32085131 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,30640168 0,32066911 ! positive regulation of immune response GO:0050778 51 51 0,000 0,30640168 0,32048712 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,30640168 0,32030533 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,30640168 0,32012376 ! protein maturation GO:0051604 51 51 0,000 0,30640168 0,31994238 ! RNA localization GO:0006403 52 52 0,000 0,31137845 0,32495497 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,31137845 0,32477107 ! cell fate commitment GO:0045165 52 52 0,000 0,31137845 0,32458738 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,31137845 0,32440389 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,31137845 0,32422061 ! sodium ion transport GO:0006814 53 53 0,000 0,31632023 0,32918022 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,31632023 0,32899446 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,31632023 0,3288089 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,31632023 0,32862355 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,32122726 0,33353343 ! response to virus GO:0009615 54 54 0,000 0,32122726 0,33334563 ! hormone metabolic process GO:0042445 55 54 0,000 0,32122726 0,33315804 ! nucleosome organization GO:0034728 55 55 0,000 0,32609978 0,33802132 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,32609978 0,33783131 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,32609978 0,33764152 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,32609978 0,33745194 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,33093804 0,34226645 ! reproductive developmental process GO:0003006 56 56 0,000 0,33093804 0,34207449 ! ATP metabolic process GO:0046034 57 57 0,000 0,33574227 0,34684585 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,33574227 0,34665154 ! innate immune response GO:0045087 58 58 0,000 0,3405127 0,35138012 ! dephosphorylation GO:0016311 60 59 0,000 0,34524956 0,35606879 ! carboxylic acid transport GO:0046942 59 59 0,000 0,34524956 0,35586965 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,34524956 0,35567073 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,34524956 0,35547203 ! protein localization in organelle GO:0033365 59 59 0,000 0,34524956 0,35527355 ! immune effector process GO:0002252 59 59 0,000 0,34524956 0,3550753 ! potassium ion transport GO:0006813 60 60 0,000 0,34995309 0,35971196 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,35462351 0,36430944 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,35926106 0,36886804 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,35926106 0,36866266 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,35926106 0,36845751 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 0,000 0,35926106 0,36825258 ! regulation of secretion GO:0051046 65 63 0,000 0,36386596 0,37276541 ! glucose metabolic process GO:0006006 63 63 0,000 0,36386596 0,37255832 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,36386596 0,37235145 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,36386596 0,37214482 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,36843844 0,37661234 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,37297871 0,381042 ! regulation of hormone levels GO:0010817 66 65 0,000 0,37297871 0,3808309 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,37748701 0,38522069 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,37748701 0,3850075 ! DNA packaging GO:0006323 66 66 0,000 0,37748701 0,38479456 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,38196355 0,38914252 ! muscle contraction GO:0006936 67 67 0,000 0,38196355 0,38892752 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,38196355 0,38871277 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,38640855 0,39301929 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,38640855 0,39280251 ! response to nutrient levels GO:0031667 69 69 0,000 0,39082223 0,39707021 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,39082223 0,39685144 ! translational elongation GO:0006414 71 71 0,000 0,39955649 0,40549703 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,39955649 0,40527386 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,39955649 0,40505094 GO:0006874|cellular calcium ion homeostasis, ! muscle system process GO:0003012 72 72 0,000 0,40387749 0,40920628 ! sensory organ development GO:0007423 72 72 0,000 0,40387749 0,40898144 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,40387749 0,40875685 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,41665856 0,42146088 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,41665856 0,42122969 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,42502973 0,42945712 ! metal ion homeostasis GO:0055065 78 78 0,000 0,42917107 0,43340399 ! regulation of immune response GO:0050776 78 78 0,000 0,42917107 0,43316664 ! nuclear transport GO:0051169 79 79 0,000 0,43328319 0,43707767 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,43736628 0,44095517 ! lymphocyte activation GO:0046649 82 81 0,000 0,44142055 0,44479939 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,44944343 0,4526362 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,45735339 0,46035079 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,45735339 0,46009951 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,46126651 0,46378297 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,46126651 0,46353009 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,46901002 0,47105475 ! chemotaxis GO:0006935 90 89 0,000 0,47284077 0,47464354 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,47664446 0,47820127 ! brain development GO:0007420 91 90 0,000 0,47664446 0,47794109 ! DNA replication GO:0006260 91 91 0,000 0,48042125 0,48146621 ! visual perception GO:0007601 93 92 0,000 0,48417134 0,48496075 GO:0050953|sensory perception of light stimulus, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,50612138 0,50667121 ! regulation of system process GO:0044057 98 98 0,000 0,50612138 0,50639615 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,51323268 0,51323268