pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6885-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! spindle assembly GO:0051225 6 5 3,000 6,71E-09 1,615E-05 ! positive regulation of locomotion GO:0040017 39 21 4,000 1,515E-07 1,823E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,659E-07 1,33E-04 ! regulation of chemotaxis GO:0050920 40 22 4,000 1,951E-07 1,174E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 2,752E-07 1,324E-04 ! natural killer cell mediated immunity GO:0002228 18 10 3,000 2,752E-07 1,103E-04 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of behavior GO:0050795 43 24 4,000 3,118E-07 1,072E-04 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 6,424E-07 1,932E-04 GO:0050927|positive regulation of positive chemotaxis, ! leukocyte mediated cytotoxicity GO:0001909 26 12 3,000 6,424E-07 1,717E-04 ! cell killing GO:0001906 29 15 3,000 1,746E-06 4,202E-04 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 2,000 2,223E-06 4,863E-04 ! polyol catabolic process GO:0046174 7 5 2,000 2,223E-06 4,458E-04 GO:0019405|alditol catabolic process, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 2,223E-06 4,115E-04 ! peptide cross-linking GO:0018149 37 19 3,000 4,865E-06 8,36E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 6,052E-06 9,707E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 6,428E-06 9,665E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 7,712E-06 1,091E-03 ! axonal fasciculation GO:0007413 18 7 2,000 7,712E-06 1,031E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 8,078E-06 1,023E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 9,018E-06 1,085E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,228E-05 1,407E-03 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 2,000 1,228E-05 1,343E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 1,228E-05 1,285E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,228E-05 1,231E-03 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,302E-05 1,253E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,815E-05 1,679E-03 GO:0045936|negative regulation of phosphate metabolic process, ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,834E-05 1,635E-03 ! negative regulation of protein modification process GO:0031400 60 28 3,000 2,462E-05 2,115E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,609E-05 2,164E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 2,609E-05 2,092E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 2,609E-05 2,025E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 3,353E-05 2,521E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,571E-05 2,603E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 3,571E-05 2,527E-03 ! neuroblast proliferation GO:0007405 24 11 2,000 3,571E-05 2,455E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 3,571E-05 2,386E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,571E-05 2,322E-03 GO:0010829|negative regulation of glucose transport, ! spindle organization GO:0007051 46 32 3,000 4,242E-05 2,686E-03 ! regulation of RNA splicing GO:0043484 20 12 2,000 4,739E-05 2,924E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 4,739E-05 2,851E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 5,728E-05 3,361E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 6,134E-05 3,514E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 6,134E-05 3,432E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 6,152E-05 3,364E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 3,000 7,607E-05 4,067E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 7,771E-05 4,065E-03 ! regulation of mRNA processing GO:0050684 24 14 2,000 7,771E-05 3,978E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 7,771E-05 3,895E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 8,097E-05 3,976E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 9,671E-05 4,653E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 9,671E-05 4,562E-03 ! fructose metabolic process GO:0006000 25 16 2,000 1,185E-04 5,482E-03 ! neuron recognition GO:0008038 35 16 2,000 1,185E-04 5,379E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 1,26E-04 5,614E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 1,418E-04 6,205E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,432E-04 6,154E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,432E-04 6,046E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,432E-04 5,942E-03 ! response to oxygen levels GO:0070482 176 83 4,000 1,592E-04 6,49E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,711E-04 6,861E-03 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 2,023E-04 7,978E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 2,305E-04 8,944E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,369E-04 9,047E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,369E-04 8,906E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,369E-04 8,769E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 29 20 2,000 2,369E-04 8,636E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,751E-04 9,881E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,751E-04 9,735E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 2,994E-04 0,01044066 ! response to UV GO:0009411 104 53 3,000 3,125E-04 0,01074212 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,172E-04 0,01074777 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 3,172E-04 0,0105985 ! interphase GO:0051325 213 98 4,000 3,458E-04 0,01139758 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,631E-04 0,01180568 ! acetyl-CoA catabolic process GO:0046356 36 23 2,000 3,631E-04 0,01164828 GO:0006099|tricarboxylic acid cycle, ! response to superoxide GO:0000303 10 5 1,000 3,668E-04 0,0116114 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,668E-04 0,0114606 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,668E-04 0,01131367 ! apoptotic cell clearance GO:0043277 20 5 1,000 3,668E-04 0,01117046 ! anagen GO:0042640 6 5 1,000 3,668E-04 0,01103083 ! skeletal myofibril assembly GO:0014866 10 5 1,000 3,668E-04 0,01089465 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,668E-04 0,01076178 ! microvillus organization GO:0032528 7 5 1,000 3,668E-04 0,01063212 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 3,668E-04 0,01050555 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,668E-04 0,01038196 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 3,668E-04 0,01026124 ! cardiac myofibril assembly GO:0055003 10 5 1,000 3,668E-04 0,01014329 ! positive regulation of blood coagulation GO:0030194 11 5 1,000 3,668E-04 0,01002803 ! positive regulation of macrophage activation GO:0043032 12 5 1,000 3,668E-04 9,915E-03 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 3,668E-04 9,805E-03 ! cell cycle arrest GO:0007050 213 100 4,000 3,796E-04 0,01003722 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 4,131E-04 0,01080378 ! alditol metabolic process GO:0019400 38 24 2,000 4,131E-04 0,01068761 ! positive regulation of cell migration GO:0030335 126 57 3,000 4,137E-04 0,01058786 ! myelination GO:0042552 45 25 2,000 4,673E-04 0,01183605 ! sperm motility GO:0030317 31 25 2,000 4,673E-04 0,01171276 ! coenzyme catabolic process GO:0009109 39 25 2,000 4,673E-04 0,01159201 ! negative regulation of cell development GO:0010721 73 25 2,000 4,673E-04 0,01147372 GO:0050768|negative regulation of neurogenesis, ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 4,721E-04 0,01147363 ! acetyl-CoA metabolic process GO:0006084 39 26 2,000 5,259E-04 0,01265394 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,259E-04 0,01252865 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 5,259E-04 0,01240582 ! response to oxygen radical GO:0000305 11 6 1,000 5,48E-04 0,01279975 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 5,48E-04 0,01267667 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 5,48E-04 0,01255594 GO:0045686|negative regulation of glial cell differentiation, ! hair follicle maturation GO:0048820 7 6 1,000 5,48E-04 0,01243749 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 1,000 5,48E-04 0,01232125 ! negative regulation of axon extension GO:0030517 21 6 1,000 5,48E-04 0,01220717 ! removal of superoxide radicals GO:0019430 11 6 1,000 5,48E-04 0,01209517 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 5,48E-04 0,01198522 ! positive regulation of coagulation GO:0050820 12 6 1,000 5,48E-04 0,01187724 ! glutathione metabolic process GO:0006749 39 27 2,000 5,89E-04 0,0126535 ! lymphocyte mediated immunity GO:0002449 114 64 3,000 6,436E-04 0,01370422 ! positive regulation of cell motion GO:0051272 146 64 3,000 6,436E-04 0,01358401 ! dendrite development GO:0016358 59 28 2,000 6,568E-04 0,01374042 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 7,293E-04 0,01512572 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 7,293E-04 0,01499644 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 7,64E-04 0,01557883 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 7,64E-04 0,01544791 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,64E-04 0,01531918 ! neuron adhesion GO:0007158 12 7 1,000 7,64E-04 0,01519257 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 7,64E-04 0,01506805 ! mRNA stabilization GO:0048255 18 7 1,000 7,64E-04 0,01494554 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,64E-04 0,01482501 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 7,64E-04 0,01470641 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 7,64E-04 0,01458969 ! rRNA modification GO:0000154 14 7 1,000 7,64E-04 0,01447482 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 7,64E-04 0,01436173 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 7,64E-04 0,0142504 ! negative regulation of focal adhesion formation GO:0051895 20 7 1,000 7,64E-04 0,01414078 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 7,64E-04 0,01403284 ! regulation of lipid transport GO:0032368 14 7 1,000 7,64E-04 0,01392653 ! oxygen homeostasis GO:0032364 12 7 1,000 7,64E-04 0,01382182 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 7,64E-04 0,01371867 GO:0002688|regulation of leukocyte chemotaxis, ! glycolipid catabolic process GO:0019377 15 7 1,000 7,64E-04 0,01361705 GO:0046479|glycosphingolipid catabolic process, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 7,655E-04 0,01354214 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 2,000 8,067E-04 0,01416651 ! ensheathment of neurons GO:0007272 57 30 2,000 8,067E-04 0,01406386 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 2,000 8,067E-04 0,01396268 ! response to heat GO:0009408 50 30 2,000 8,067E-04 0,01386295 ! iron ion homeostasis GO:0055072 54 31 2,000 8,891E-04 0,01517123 ! hexose biosynthetic process GO:0019319 48 32 2,000 9,767E-04 0,01654843 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 9,767E-04 0,01643271 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 1,015E-03 0,0169529 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,015E-03 0,01683598 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,015E-03 0,01672067 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 1,000 1,015E-03 0,01660692 ! ganglioside metabolic process GO:0001573 19 8 1,000 1,015E-03 0,01649471 ! ER overload response GO:0006983 12 8 1,000 1,015E-03 0,01638401 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,015E-03 0,01627478 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,015E-03 0,016167 ! negative regulation of translational initiation GO:0045947 10 8 1,000 1,015E-03 0,01606064 ! cardiac muscle cell development GO:0055013 13 8 1,000 1,015E-03 0,01595567 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,015E-03 0,01585206 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 1,015E-03 0,01574979 ! regulation of macrophage activation GO:0043030 15 8 1,000 1,015E-03 0,01564883 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 1,015E-03 0,01554915 ! neuromuscular process controlling posture GO:0050884 14 8 1,000 1,015E-03 0,01545074 ! negative regulation of organic acid transport GO:0032891 13 8 1,000 1,015E-03 0,01535357 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 1,000 1,015E-03 0,01525761 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,015E-03 0,01516284 ! axon guidance GO:0007411 139 73 3,000 1,057E-03 0,01569163 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,07E-03 0,01578716 GO:0060326|cell chemotaxis, ! leukocyte mediated immunity GO:0002443 128 74 3,000 1,112E-03 0,01630861 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,272E-03 0,01854182 ! regulation of microtubule-based process GO:0032886 78 35 2,000 1,272E-03 0,01843012 ! microtubule bundle formation GO:0001578 21 9 1,000 1,299E-03 0,01871915 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,299E-03 0,01860773 ! motor axon guidance GO:0008045 16 9 1,000 1,299E-03 0,01849762 ! gas homeostasis GO:0033483 16 9 1,000 1,299E-03 0,01838881 ! regulation of fibrinolysis GO:0051917 16 9 1,000 1,299E-03 0,01828128 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,299E-03 0,01817499 ! aerobic respiration GO:0009060 55 36 2,000 1,381E-03 0,01920588 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,381E-03 0,0190955 ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 1,381E-03 0,01898638 ! actomyosin structure organization GO:0031032 62 37 2,000 1,496E-03 0,0204525 ! glycogen metabolic process GO:0005977 61 37 2,000 1,496E-03 0,02033695 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,496E-03 0,0202227 ! response to hypoxia GO:0001666 171 81 3,000 1,555E-03 0,02090161 ! regulation of neuron differentiation GO:0045664 167 81 3,000 1,555E-03 0,02078549 ! glucan metabolic process GO:0044042 62 38 2,000 1,617E-03 0,02149576 GO:0006073|cellular glucan metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,618E-03 0,02138424 ! negative regulation of blood pressure GO:0045776 26 10 1,000 1,618E-03 0,02126739 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,618E-03 0,02115181 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,618E-03 0,02103747 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 1,618E-03 0,02092437 ! lung alveolus development GO:0048286 26 10 1,000 1,618E-03 0,02081247 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,618E-03 0,02070177 GO:0005978|glycogen biosynthetic process, ! phagocytosis, engulfment GO:0006911 28 10 1,000 1,618E-03 0,02059224 ! regulation of bone resorption GO:0045124 25 10 1,000 1,618E-03 0,02048386 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,618E-03 0,02037661 GO:0045685|regulation of glial cell differentiation, ! negative regulation of axonogenesis GO:0050771 32 10 1,000 1,618E-03 0,02027048 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 1,618E-03 0,02016545 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,618E-03 0,02006151 ! localization within membrane GO:0051668 20 10 1,000 1,618E-03 0,01995863 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,744E-03 0,02140891 ! negative regulation of transport GO:0051051 153 84 3,000 1,778E-03 0,02171549 ! mesenchymal cell development GO:0014031 87 40 2,000 1,877E-03 0,02280875 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! mitochondrion organization GO:0007005 148 86 3,000 1,938E-03 0,02343683 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,969E-03 0,02368858 ! blood vessel remodeling GO:0001974 29 11 1,000 1,969E-03 0,02357072 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,969E-03 0,02345404 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,969E-03 0,0233385 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,969E-03 0,02322409 ! regulation of organic acid transport GO:0032890 18 11 1,000 1,969E-03 0,02311081 ! polyol metabolic process GO:0019751 66 41 2,000 2,016E-03 0,02354821 ! cellular respiration GO:0045333 135 88 3,000 2,109E-03 0,02450898 ! response to reactive oxygen species GO:0000302 67 42 2,000 2,162E-03 0,02500377 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 2,162E-03 0,02488413 ! alcohol biosynthetic process GO:0046165 59 42 2,000 2,162E-03 0,02476564 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 2,197E-03 0,02505731 ! energy reserve metabolic process GO:0006112 74 43 2,000 2,313E-03 0,02625432 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,313E-03 0,02613106 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 2,353E-03 0,02646005 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,353E-03 0,02633698 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,353E-03 0,02621505 ! hippocampus development GO:0021766 26 12 1,000 2,353E-03 0,02609425 ! negative regulation of endothelial cell migration GO:0010596 25 12 1,000 2,353E-03 0,02597455 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,353E-03 0,02585594 ! histone acetylation GO:0016573 26 12 1,000 2,353E-03 0,02573842 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,353E-03 0,02562195 ! T cell homeostasis GO:0043029 25 12 1,000 2,353E-03 0,02550654 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,353E-03 0,02539216 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,579E-03 0,02769734 ! carbohydrate biosynthetic process GO:0016051 141 93 3,000 2,579E-03 0,02757424 ! leukocyte migration GO:0050900 68 45 2,000 2,636E-03 0,02806602 ! lipid localization GO:0010876 28 13 1,000 2,77E-03 0,02936192 GO:0019915|lipid storage, ! Golgi organization GO:0007030 24 13 1,000 2,77E-03 0,02923314 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,77E-03 0,02910549 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,77E-03 0,02897894 ! negative regulation of cell migration GO:0030336 115 46 2,000 2,808E-03 0,0292434 ! response to insulin stimulus GO:0032868 95 46 2,000 2,808E-03 0,02911735 ! positive regulation of defense response GO:0031349 76 47 2,000 2,986E-03 0,03083123 ! vascular process in circulatory system GO:0003018 80 47 2,000 2,986E-03 0,03069947 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,171E-03 0,0324616 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,171E-03 0,03232405 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,171E-03 0,03218766 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,219E-03 0,0325414 ! regulated secretory pathway GO:0045055 23 14 1,000 3,219E-03 0,03240524 ! response to gamma radiation GO:0010332 28 14 1,000 3,219E-03 0,03227022 ! regulation of RNA stability GO:0043487 32 14 1,000 3,219E-03 0,03213632 ! regulation of axon extension GO:0030516 37 14 1,000 3,219E-03 0,03200352 ! regulation of action potential GO:0001508 95 49 2,000 3,362E-03 0,03329144 ! peptide metabolic process GO:0006518 76 49 2,000 3,362E-03 0,033155 ! response to temperature stimulus GO:0009266 76 49 2,000 3,362E-03 0,03301968 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,561E-03 0,03482887 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,699E-03 0,03603471 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,699E-03 0,03588941 ! sulfate transport GO:0008272 23 15 1,000 3,699E-03 0,03574527 ! response to hexose stimulus GO:0009746 22 15 1,000 3,699E-03 0,03560229 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 3,699E-03 0,03546045 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,699E-03 0,03531973 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,699E-03 0,03518013 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,767E-03 0,03568073 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 2,000 3,767E-03 0,0355408 ! regulation of angiogenesis GO:0045765 114 52 2,000 3,98E-03 0,03740239 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,98E-03 0,03725685 ! cartilage development GO:0051216 90 52 2,000 3,98E-03 0,03711245 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 4,2E-03 0,03901311 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 4,211E-03 0,03896676 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,211E-03 0,03881746 GO:0031114|regulation of microtubule depolymerization, ! intermediate filament-based process GO:0045103 32 16 1,000 4,211E-03 0,0386693 ! axon cargo transport GO:0008088 43 16 1,000 4,211E-03 0,03852227 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,211E-03 0,03837636 ! sphingolipid catabolic process GO:0030149 27 16 1,000 4,211E-03 0,03823154 GO:0046466|membrane lipid catabolic process, ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,211E-03 0,03808781 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,211E-03 0,03794516 ! cell recognition GO:0008037 85 54 2,000 4,427E-03 0,03974338 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 4,662E-03 0,04169395 ! negative regulation of cell motion GO:0051271 134 55 2,000 4,662E-03 0,04153952 ! limbic system development GO:0021761 36 17 1,000 4,753E-03 0,04220021 ! adult walking behavior GO:0007628 33 17 1,000 4,753E-03 0,04204506 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,753E-03 0,04189105 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,753E-03 0,04173816 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,753E-03 0,04158639 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,753E-03 0,04143571 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,326E-03 0,04626112 ! memory GO:0007613 31 18 1,000 5,326E-03 0,04609471 ! patterning of blood vessels GO:0001569 39 18 1,000 5,326E-03 0,0459295 ! positive regulation of proteolysis GO:0045862 31 18 1,000 5,326E-03 0,04576546 ! cell-substrate junction assembly GO:0007044 54 18 1,000 5,326E-03 0,0456026 ! positive regulation of translation GO:0045727 30 19 1,000 5,929E-03 0,05058384 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 5,929E-03 0,05040509 ! lipid phosphorylation GO:0046834 35 19 1,000 5,929E-03 0,05022761 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,929E-03 0,05005137 ! neuromuscular junction development GO:0007528 34 19 1,000 5,929E-03 0,04987637 ! heart process GO:0003015 30 19 1,000 5,929E-03 0,04970258 GO:0060047|heart contraction, ! regulation of heart contraction GO:0008016 110 60 2,000 5,947E-03 0,04967889 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 5,947E-03 0,049507 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 6,226E-03 0,05165805 ! regulation of homeostatic process GO:0032844 134 62 2,000 6,514E-03 0,05385835 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,561E-03 0,05406257 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,561E-03 0,05387805 ! response to alkaloid GO:0043279 38 20 1,000 6,561E-03 0,0536948 ! response to carbohydrate stimulus GO:0009743 29 20 1,000 6,561E-03 0,05351278 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 6,561E-03 0,05333199 ! detection of chemical stimulus GO:0009593 37 20 1,000 6,561E-03 0,05315242 ! leukotriene biosynthetic process GO:0019370 37 20 1,000 6,561E-03 0,05297406 GO:0043450|alkene biosynthetic process, ! actin filament-based movement GO:0030048 43 20 1,000 6,561E-03 0,05279689 ! negative regulation of T cell activation GO:0050868 40 20 1,000 6,561E-03 0,0526209 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 6,809E-03 0,05443018 ! cell redox homeostasis GO:0045454 102 64 2,000 7,113E-03 0,0566658 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 7,223E-03 0,05735412 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 7,223E-03 0,05716545 ! vasodilation GO:0042311 39 21 1,000 7,223E-03 0,05697803 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 7,913E-03 0,06222163 ! microtubule-based transport GO:0010970 54 22 1,000 7,913E-03 0,06201895 ! glutamate signaling pathway GO:0007215 41 22 1,000 7,913E-03 0,06181759 ! lysosome organization GO:0007040 41 22 1,000 7,913E-03 0,06161754 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,913E-03 0,06141877 ! apoptotic nuclear changes GO:0030262 32 22 1,000 7,913E-03 0,06122128 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 7,913E-03 0,06102506 GO:0060415|muscle tissue morphogenesis, ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,913E-03 0,06083009 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,913E-03 0,06063636 ! lung development GO:0030324 144 67 2,000 8,07E-03 0,06163896 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 8,405E-03 0,06399532 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,633E-03 0,06552029 ! leukocyte adhesion GO:0007159 50 23 1,000 8,633E-03 0,06531425 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,633E-03 0,06510951 GO:0010810|regulation of cell-substrate adhesion, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 8,633E-03 0,06490604 ! leukotriene metabolic process GO:0006691 42 23 1,000 8,633E-03 0,06470384 ! glycosphingolipid metabolic process GO:0006687 41 23 1,000 8,633E-03 0,0645029 ! negative regulation of cytokine production GO:0001818 40 23 1,000 8,633E-03 0,0643032 ! negative regulation of cell size GO:0045792 134 69 2,000 8,748E-03 0,06496357 ! respiratory tube development GO:0030323 150 70 2,000 9,099E-03 0,06736429 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 9,38E-03 0,06922622 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 9,38E-03 0,06901452 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 9,38E-03 0,06880411 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 9,38E-03 0,06859498 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 9,38E-03 0,06838712 ! vacuole organization GO:0007033 43 24 1,000 9,38E-03 0,06818051 ! pallium development GO:0021543 49 24 1,000 9,38E-03 0,06797515 ! leukocyte homeostasis GO:0001776 44 24 1,000 9,38E-03 0,06777102 ! cellular alkene metabolic process GO:0043449 43 24 1,000 9,38E-03 0,06756811 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 9,827E-03 0,07057534 ! respiratory system development GO:0060541 153 72 2,000 9,827E-03 0,07036529 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01015477 0,07249966 ! vasculogenesis GO:0001570 46 25 1,000 0,01015477 0,07228517 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01015477 0,07207194 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01015477 0,07185996 ! somitogenesis GO:0001756 43 25 1,000 0,01015477 0,07164923 ! regulation of blood coagulation GO:0030193 40 25 1,000 0,01015477 0,07143973 ! neuromuscular process controlling balance GO:0050885 60 25 1,000 0,01015477 0,07123145 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 0,01095718 0,07663654 ! molting cycle process GO:0022404 50 26 1,000 0,01095718 0,0764144 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01095718 0,07619355 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01178663 0,08172516 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01178663 0,08149032 ! iron ion transport GO:0006826 59 27 1,000 0,01178663 0,08125682 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01178663 0,08102466 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01178663 0,08079382 ! superoxide metabolic process GO:0006801 38 27 1,000 0,01178663 0,08056429 ! glycolipid metabolic process GO:0006664 47 27 1,000 0,01178663 0,08033607 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01178663 0,08010913 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01178663 0,07988347 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01178663 0,07965908 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,0126321 0,08513397 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01264277 0,08496792 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01264277 0,08473124 ! icosanoid biosynthetic process GO:0046456 54 29 1,000 0,01352526 0,0903938 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01352526 0,0901434 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01352526 0,08989439 ! regulation of coagulation GO:0050818 46 29 1,000 0,01352526 0,08964675 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01396035 0,09227641 ! cell junction assembly GO:0034329 78 30 1,000 0,01443373 0,09514398 ! acute-phase response GO:0006953 49 30 1,000 0,01443373 0,09488402 ! myofibril assembly GO:0030239 47 30 1,000 0,01443373 0,09462548 GO:0055002|striated muscle cell development, ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01443373 0,09436835 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01443373 0,0941126 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01443373 0,09385825 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01536504 0,09964499 GO:0002696|positive regulation of leukocyte activation, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01536784 0,09939524 ! alcohol catabolic process GO:0046164 130 86 2,000 0,01585034 0,10224107 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01632725 0,10503575 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 0,01632725 0,10475566 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01632725 0,10447705 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01632725 0,10419992 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,01632725 0,10392426 ! muscle cell development GO:0055001 49 32 1,000 0,01632725 0,10365006 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01632725 0,10337729 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01632725 0,10310596 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01632725 0,10283605 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01684663 0,10583027 ! post-embryonic development GO:0009791 69 33 1,000 0,01731162 0,10846813 ! ceramide metabolic process GO:0006672 64 33 1,000 0,01731162 0,10818639 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01731162 0,10790612 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01735765 0,10791344 ! ossification GO:0001503 188 90 2,000 0,01787726 0,11085746 ! placenta development GO:0001890 53 34 1,000 0,01832061 0,11331463 ! bone development GO:0060348 189 91 2,000 0,01840548 0,11354767 ! regulation of defense response GO:0031347 149 92 2,000 0,01894232 0,11656065 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01935389 0,11878941 ! telencephalon development GO:0021537 68 35 1,000 0,01935389 0,11848715 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01935389 0,11818642 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01948777 0,11870274 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01948777 0,11840298 ! cell junction organization GO:0034330 86 36 1,000 0,02041112 0,12370062 ! sphingoid metabolic process GO:0046519 70 36 1,000 0,02041112 0,12338981 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02041112 0,12308057 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02041112 0,12277286 ! detection of stimulus GO:0051606 151 96 2,000 0,02117592 0,12705554 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,02149197 0,12863107 ! tissue remodeling GO:0048771 76 37 1,000 0,02149197 0,12831188 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,02259613 0,13457004 ! nucleus organization GO:0006997 67 38 1,000 0,02259613 0,13423777 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02259613 0,13390714 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,02259613 0,13357813 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02294181 0,13528922 GO:0060538|skeletal muscle organ development, ! mammary gland development GO:0030879 86 39 1,000 0,02372327 0,1395555 ! ear morphogenesis GO:0042471 60 39 1,000 0,02372327 0,13921512 ! segmentation GO:0035282 67 39 1,000 0,02372327 0,13887639 ! RNA modification GO:0009451 57 39 1,000 0,02372327 0,13853931 ! cytokinesis GO:0000910 72 40 1,000 0,02487308 0,14490223 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02604522 0,15136428 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02604522 0,15099955 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02604522 0,15063657 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02723941 0,1571655 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02723941 0,1567895 ! regulation of tube size GO:0035150 71 42 1,000 0,02723941 0,1564153 GO:0050880|regulation of blood vessel size, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02723941 0,15604289 ! neuron migration GO:0001764 79 42 1,000 0,02723941 0,15567224 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02845531 0,16223574 ! glucose transport GO:0015758 65 43 1,000 0,02845531 0,1618522 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02845531 0,16147047 ! phagocytosis GO:0006909 90 43 1,000 0,02845531 0,16109054 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,02845531 0,1607124 ! hexose transport GO:0008645 67 44 1,000 0,02969263 0,16730791 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02969263 0,166917 ! double-strand break repair GO:0006302 81 44 1,000 0,02969263 0,16652792 ! developmental growth GO:0048589 82 44 1,000 0,02969263 0,16614064 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03017852 0,16846758 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03017852 0,16807761 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03017852 0,16768944 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03017852 0,16730306 ! neuron fate determination GO:0048664 7 5 0,000 0,03017852 0,16691846 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03017852 0,16653562 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03017852 0,16615453 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03017852 0,16577518 ! polyol transport GO:0015791 12 5 0,000 0,03017852 0,16539756 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03017852 0,16502165 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03017852 0,16464746 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03017852 0,16427495 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03017852 0,16390413 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03017852 0,16353497 ! female meiosis GO:0007143 7 5 0,000 0,03017852 0,16316748 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03017852 0,16280163 ! cobalt ion transport GO:0006824 11 5 0,000 0,03017852 0,16243742 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03017852 0,16207484 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03017852 0,16171387 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03017852 0,16135451 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03017852 0,16099674 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03017852 0,16064055 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03017852 0,16028593 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03017852 0,15993288 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03017852 0,15958138 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03017852 0,15923142 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03017852 0,15888299 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03017852 0,15853609 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03017852 0,15819069 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,03017852 0,1578468 ! negative chemotaxis GO:0050919 14 5 0,000 0,03017852 0,1575044 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03017852 0,15716348 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03017852 0,15682403 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03017852 0,15648605 ! behavioral response to pain GO:0048266 9 5 0,000 0,03017852 0,15614952 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03017852 0,15581444 ! Notch receptor processing GO:0007220 8 5 0,000 0,03017852 0,15548079 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03017852 0,15514856 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03017852 0,15481776 ! micturition GO:0060073 9 5 0,000 0,03017852 0,15448836 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03017852 0,15416036 ! copulation GO:0007620 9 5 0,000 0,03017852 0,15383375 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03017852 0,15350852 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03017852 0,15318466 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03017852 0,15286216 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03017852 0,15254103 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03017852 0,15222123 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03017852 0,15190278 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03017852 0,15158565 ! grooming behavior GO:0007625 6 5 0,000 0,03017852 0,15126985 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03017852 0,15095536 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03017852 0,15064217 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03017852 0,15033029 ! response to protozoan GO:0001562 10 5 0,000 0,03017852 0,15001969 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,03017852 0,14971037 ! lymph vessel development GO:0001945 10 5 0,000 0,03017852 0,14940232 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03017852 0,14909554 ! endochondral ossification GO:0001958 16 5 0,000 0,03017852 0,14879002 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03017852 0,14848574 ! parathyroid gland development GO:0060017 13 5 0,000 0,03017852 0,14818271 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03017852 0,14788091 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03017852 0,14758034 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03017852 0,14728099 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03017852 0,14698285 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03017852 0,14668592 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03017852 0,14639018 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03017852 0,14609563 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03017852 0,14580227 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03017852 0,14551008 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03017852 0,14521906 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03017852 0,1449292 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03017852 0,14464049 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03017852 0,14435294 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03017852 0,14406652 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03017852 0,14378124 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03017852 0,14349709 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03017852 0,14321406 ! histidine catabolic process GO:0006548 6 5 0,000 0,03017852 0,14293214 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03017852 0,14265133 ! valine metabolic process GO:0006573 10 5 0,000 0,03017852 0,14237162 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03017852 0,14209301 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03017852 0,14181548 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03017852 0,14153904 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03017852 0,14126367 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03017852 0,14098938 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03017852 0,14071614 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03017852 0,14044396 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03017852 0,14017283 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03017852 0,13990275 ! muscle cell migration GO:0014812 8 5 0,000 0,03017852 0,13963371 ! mitochondrial fission GO:0000266 8 5 0,000 0,03017852 0,1393657 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03017852 0,13909871 ! mRNA transcription GO:0009299 9 5 0,000 0,03017852 0,13883275 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03017852 0,1385678 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03017852 0,13830386 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03017852 0,13804093 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03017852 0,13777899 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03017852 0,13751805 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03017852 0,13725809 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03017852 0,13699911 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03017852 0,13674111 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03017852 0,13648408 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03017852 0,13622801 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03017852 0,1359729 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03017852 0,13571874 ! forebrain neuron development GO:0021884 13 5 0,000 0,03017852 0,13546554 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03017852 0,13521327 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03017852 0,13496195 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03017852 0,13471156 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03017852 0,13446209 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03017852 0,13421355 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03017852 0,13396592 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03017852 0,1337192 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03017852 0,1334734 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03017852 0,13322849 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03017852 0,13298448 ! basic amino acid transport GO:0015802 11 5 0,000 0,03017852 0,13274137 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03017852 0,13249914 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03017852 0,13225779 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03017852 0,13201732 ! depyrimidination GO:0045008 10 5 0,000 0,03017852 0,13177773 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03017852 0,131539 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03017852 0,13130114 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03017852 0,13106413 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03017852 0,13082798 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,03017852 0,13059268 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03017852 0,13035822 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03017852 0,1301246 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03017852 0,12989182 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03017852 0,12965987 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03017852 0,12942875 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03017852 0,12919845 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03017852 0,12896897 ! response to arsenic GO:0046685 10 5 0,000 0,03017852 0,1287403 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03017852 0,12851244 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03017852 0,12828539 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03017852 0,12805913 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03017852 0,12783368 ! response to cadmium ion GO:0046686 7 5 0,000 0,03017852 0,12760901 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03017852 0,12738514 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03017852 0,12716205 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03017852 0,12693973 ! decidualization GO:0046697 11 5 0,000 0,03017852 0,1267182 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03017852 0,12649744 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03017852 0,12627744 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03017852 0,12605821 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03017852 0,12583974 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03017852 0,12562202 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03017852 0,12540506 ! neural tube patterning GO:0021532 7 5 0,000 0,03017852 0,12518884 ! embryonic cleavage GO:0040016 6 5 0,000 0,03017852 0,12497337 ! peroxisome fission GO:0016559 5 5 0,000 0,03017852 0,12475864 ! histone demethylation GO:0016577 10 5 0,000 0,03017852 0,12454465 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03017852 0,12433138 ! mitotic recombination GO:0006312 9 5 0,000 0,03017852 0,12411885 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03017852 0,12390704 ! metaphase plate congression GO:0051310 7 5 0,000 0,03017852 0,12369596 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03017852 0,12348559 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03017852 0,12327594 ! enteric nervous system development GO:0048484 8 5 0,000 0,03017852 0,123067 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03017852 0,12285876 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03017852 0,12265123 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03017852 0,1224444 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03017852 0,12223826 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03017852 0,12203282 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03017852 0,12182807 ! plasminogen activation GO:0031639 5 5 0,000 0,03017852 0,121624 ! B cell homeostasis GO:0001782 13 5 0,000 0,03017852 0,12142062 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03017852 0,12121791 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03017852 0,12101588 ! metaphase GO:0051323 8 5 0,000 0,03017852 0,12081452 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03017852 0,12061383 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03017852 0,12041381 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03017852 0,12021445 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03017852 0,12001575 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03017852 0,1198177 ! response to redox state GO:0051775 5 5 0,000 0,03017852 0,11962031 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03017852 0,11942357 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03017852 0,11922747 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03017852 0,11903201 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03017852 0,1188372 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03017852 0,11864302 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03017852 0,11844948 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03017852 0,11825656 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03017852 0,11806427 ! striatum development GO:0021756 9 5 0,000 0,03017852 0,11787261 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03017852 0,11768157 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03017852 0,11749115 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03017852 0,11730134 ! glial cell migration GO:0008347 11 5 0,000 0,03017852 0,11711214 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03017852 0,11692356 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03017852 0,11673558 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03017852 0,1165482 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03017852 0,11636142 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03017852 0,11617525 ! neuroprotection GO:0043526 6 5 0,000 0,03017852 0,11598966 ! neural plate development GO:0001840 8 5 0,000 0,03017852 0,11580467 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03017852 0,11562027 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03017852 0,11543645 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03017852 0,11525322 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03017852 0,11507057 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03017852 0,11488849 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03017852 0,114707 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03017852 0,11452607 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03017852 0,11434571 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03017852 0,11416592 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03017852 0,1139867 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03017852 0,11380804 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03017852 0,11362993 ! drug metabolic process GO:0017144 6 5 0,000 0,03017852 0,11345239 ! stem cell division GO:0017145 11 5 0,000 0,03017852 0,1132754 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,03017852 0,11309895 ! organ regeneration GO:0031100 7 5 0,000 0,03017852 0,11292306 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03017852 0,11274771 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03017852 0,11257291 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03017852 0,11239865 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03095107 0,11509779 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03095107 0,11492017 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,03095107 0,1147431 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,03095107 0,11456657 ! cell growth GO:0016049 84 45 1,000 0,03095107 0,11439058 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,03223031 0,11893579 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,03223031 0,11875365 ! pigmentation GO:0043473 100 46 1,000 0,03223031 0,11857207 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03223031 0,11839105 ! response to calcium ion GO:0051592 81 47 1,000 0,03353007 0,12297768 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03353007 0,1227905 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,03353007 0,12260389 ! cellular component disassembly GO:0022411 86 48 1,000 0,03485005 0,12723706 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03485005 0,12704427 ! activation of caspase activity GO:0006919 84 48 1,000 0,03485005 0,12685207 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03485005 0,12666045 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03610464 0,13102226 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03610464 0,13082494 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03610464 0,13062821 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03610464 0,13043207 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03610464 0,13023652 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03610464 0,13004156 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03610464 0,12984717 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03610464 0,12965337 ! sleep GO:0030431 13 6 0,000 0,03610464 0,12946015 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03610464 0,1292675 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03610464 0,12907542 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03610464 0,12888392 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03610464 0,12869298 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03610464 0,1285026 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03610464 0,12831279 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03610464 0,12812354 ! forebrain regionalization GO:0021871 8 6 0,000 0,03610464 0,12793484 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03610464 0,1277467 ! male meiosis GO:0007140 7 6 0,000 0,03610464 0,12755912 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03610464 0,12737208 ! response to zinc ion GO:0010043 9 6 0,000 0,03610464 0,12718559 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03610464 0,12699965 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03610464 0,12681425 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03610464 0,12662939 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03610464 0,12644506 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03610464 0,12626128 ! malate metabolic process GO:0006108 11 6 0,000 0,03610464 0,12607802 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03610464 0,1258953 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03610464 0,12571311 ! protein refolding GO:0042026 15 6 0,000 0,03610464 0,12553144 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03610464 0,1253503 ! opsonization GO:0008228 8 6 0,000 0,03610464 0,12516968 ! mating behavior GO:0007617 7 6 0,000 0,03610464 0,12498958 ! neuron remodeling GO:0016322 15 6 0,000 0,03610464 0,12481 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03610464 0,12463093 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03610464 0,12445238 ! equilibrioception GO:0050957 14 6 0,000 0,03610464 0,12427433 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03610464 0,1240968 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03610464 0,12391977 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03610464 0,12374325 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03610464 0,12356722 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03610464 0,1233917 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03610464 0,12321668 ! toxin metabolic process GO:0009404 11 6 0,000 0,03610464 0,12304215 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03610464 0,12286812 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03610464 0,12269457 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03610464 0,12252152 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03610464 0,12234896 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03610464 0,12217688 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03610464 0,12200528 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03610464 0,12183416 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03610464 0,12166353 ! thymic T cell selection GO:0045061 12 6 0,000 0,03610464 0,12149337 ! protein lipoylation GO:0009249 10 6 0,000 0,03610464 0,12132369 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03610464 0,12115448 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03610464 0,12098574 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03610464 0,12081747 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03610464 0,12064967 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03610464 0,12048233 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03610464 0,12031546 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03610464 0,12014904 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03610464 0,11998309 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03610464 0,1198176 ! hyperosmotic response GO:0006972 9 6 0,000 0,03610464 0,11965256 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03610464 0,11948798 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03610464 0,11932384 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03610464 0,11916016 ! urea metabolic process GO:0019627 7 6 0,000 0,03610464 0,11899693 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03610464 0,11883414 ! neutrophil activation GO:0042119 8 6 0,000 0,03610464 0,1186718 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03610464 0,1185099 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03610464 0,11834845 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03610464 0,11818743 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03610464 0,11802685 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03610464 0,1178667 ! neuron apoptosis GO:0051402 9 6 0,000 0,03610464 0,11770699 ! nucleoside salvage GO:0043174 9 6 0,000 0,03610464 0,11754771 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03610464 0,11738886 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03610464 0,11723044 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03610464 0,11707245 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03610464 0,11691488 ! carnitine transport GO:0015879 10 6 0,000 0,03610464 0,11675774 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03610464 0,11660102 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03610464 0,11644472 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03610464 0,11628883 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03610464 0,11613337 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03610464 0,11597832 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03610464 0,11582368 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03610464 0,11566945 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03610464 0,11551564 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03610464 0,11536223 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03610464 0,11520923 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03610464 0,11505663 ! monocyte differentiation GO:0030224 12 6 0,000 0,03610464 0,11490444 ! neural nucleus development GO:0048857 14 6 0,000 0,03610464 0,11475265 ! response to UV-C GO:0010225 11 6 0,000 0,03610464 0,11460127 ! astrocyte development GO:0014002 15 6 0,000 0,03610464 0,11445028 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03610464 0,11429968 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03610464 0,11414949 ! interaction with symbiont GO:0051702 13 6 0,000 0,03610464 0,11399968 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03610464 0,11385027 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03610464 0,11370126 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03610464 0,11355263 ! response to copper ion GO:0046688 10 6 0,000 0,03610464 0,11340439 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03610464 0,11325653 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03610464 0,11310906 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03610464 0,11296198 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03610464 0,11281527 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03610464 0,11266895 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03610464 0,112523 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03610464 0,11237744 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03610464 0,11223225 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03610464 0,11208743 ! Schwann cell development GO:0014044 15 6 0,000 0,03610464 0,11194299 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03610464 0,11179892 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03610464 0,11165522 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03610464 0,11151189 ! subpallium development GO:0021544 10 6 0,000 0,03610464 0,11136892 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03610464 0,11122632 ! histone ubiquitination GO:0016574 8 6 0,000 0,03610464 0,11108409 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03610464 0,11094222 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03610464 0,11080071 ! G2 phase GO:0051319 16 6 0,000 0,03610464 0,11065957 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03610464 0,11051878 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03610464 0,11037835 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03610464 0,11023827 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03610464 0,11009855 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03610464 0,10995919 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03610464 0,10982018 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03610464 0,10968151 ! receptor internalization GO:0031623 10 6 0,000 0,03610464 0,1095432 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03610464 0,10940524 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03610464 0,10926762 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03610464 0,10913035 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03610464 0,10899342 ! protein deubiquitination GO:0016579 14 6 0,000 0,03610464 0,10885684 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03610464 0,1087206 ! protein destabilization GO:0031648 9 6 0,000 0,03610464 0,1085847 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03610464 0,10844914 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03610464 0,10831391 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03610464 0,10817903 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03610464 0,10804448 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03610464 0,10791026 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03610464 0,10777638 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03610464 0,10764282 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03610464 0,1075096 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03610464 0,10737671 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03610464 0,10724415 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03610464 0,10711191 ! catecholamine transport GO:0051937 9 6 0,000 0,03610464 0,10698 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03610464 0,10684841 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03610464 0,10671715 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03610464 0,10658621 ! maternal placenta development GO:0001893 12 6 0,000 0,03610464 0,10645559 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03610464 0,10632529 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03610464 0,1061953 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03610464 0,10606564 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03610464 0,10593629 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03610464 0,10580726 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03610464 0,10567854 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03618995 0,10579954 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,03618995 0,10567115 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03618995 0,10554306 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,03754949 0,10937539 ! neuromuscular process GO:0050905 99 50 1,000 0,03754949 0,10924313 ! histone modification GO:0016570 91 50 1,000 0,03754949 0,1091112 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03754949 0,10897958 ! positive regulation of binding GO:0051099 78 51 1,000 0,03892838 0,11284539 ! positive regulation of growth GO:0045927 90 52 1,000 0,04032632 0,11675708 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04032632 0,11661675 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,04032632 0,11647676 ! amino acid activation GO:0043038 92 52 1,000 0,04032632 0,11633709 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,04032632 0,11619777 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,04174306 0,12013612 ! regulation of translational initiation GO:0006446 82 53 1,000 0,04174306 0,11999258 ! tRNA transcription GO:0009304 14 7 0,000 0,04199474 0,120572 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04199474 0,12042829 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04199474 0,12028492 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04199474 0,1201419 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04199474 0,11999921 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04199474 0,11985686 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04199474 0,11971485 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04199474 0,11957318 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04199474 0,11943184 ! prostate gland development GO:0030850 13 7 0,000 0,04199474 0,11929083 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04199474 0,11915016 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04199474 0,11900982 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04199474 0,11886981 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04199474 0,11873012 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04199474 0,11859077 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04199474 0,11845174 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04199474 0,11831304 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04199474 0,11817466 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04199474 0,11803661 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04199474 0,11789887 ! glycolipid transport GO:0046836 10 7 0,000 0,04199474 0,11776146 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04199474 0,11762437 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04199474 0,1174876 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04199474 0,11735114 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04199474 0,11721501 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04199474 0,11707918 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04199474 0,11694368 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04199474 0,11680848 ! pericardium development GO:0060039 14 7 0,000 0,04199474 0,1166736 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04199474 0,11653903 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04199474 0,11640476 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04199474 0,11627081 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04199474 0,11613717 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04199474 0,11600383 ! lipoprotein transport GO:0042953 14 7 0,000 0,04199474 0,1158708 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04199474 0,11573807 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04199474 0,11560565 ! rhythmic behavior GO:0007622 15 7 0,000 0,04199474 0,11547353 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04199474 0,11534171 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04199474 0,11521019 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04199474 0,11507897 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04199474 0,11494805 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04199474 0,11481743 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04199474 0,1146871 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04199474 0,11455707 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04199474 0,11442733 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04199474 0,11429789 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04199474 0,11416874 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04199474 0,11403988 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04199474 0,11391131 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04199474 0,11378304 ! spinal cord patterning GO:0021511 13 7 0,000 0,04199474 0,11365505 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04199474 0,11352734 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04199474 0,11339993 ! adrenal gland development GO:0030325 17 7 0,000 0,04199474 0,1132728 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04199474 0,11314595 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04199474 0,11301939 ! ovulation GO:0030728 9 7 0,000 0,04199474 0,11289311 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04199474 0,11276712 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04199474 0,1126414 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,04199474 0,11251596 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04199474 0,11239081 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04199474 0,11226593 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04199474 0,11214133 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04199474 0,112017 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04199474 0,11189295 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04199474 0,11176918 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04199474 0,11164567 ! galactose metabolic process GO:0006012 13 7 0,000 0,04199474 0,11152245 ! vesicle fusion GO:0006906 17 7 0,000 0,04199474 0,11139949 ! response to dietary excess GO:0002021 8 7 0,000 0,04199474 0,1112768 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04199474 0,11115438 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04199474 0,11103224 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04199474 0,11091036 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04199474 0,11078874 ! organ growth GO:0035265 15 7 0,000 0,04199474 0,1106674 ! purine salvage GO:0043101 10 7 0,000 0,04199474 0,11054632 ! nucleoside transport GO:0015858 8 7 0,000 0,04199474 0,1104255 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04199474 0,11030495 ! parturition GO:0007567 14 7 0,000 0,04199474 0,11018466 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04199474 0,11006464 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04199474 0,10994487 ! spindle checkpoint GO:0031577 15 7 0,000 0,04199474 0,10982536 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04199474 0,10970612 ! macrophage differentiation GO:0030225 11 7 0,000 0,04199474 0,10958713 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04199474 0,1094684 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04199474 0,10934993 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04199474 0,10923171 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04199474 0,10911375 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04199474 0,10899605 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04199474 0,10887859 ! fibrinolysis GO:0042730 10 7 0,000 0,04199474 0,10876139 ! eating behavior GO:0042755 7 7 0,000 0,04199474 0,10864445 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04199474 0,10852775 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04199474 0,1084113 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04199474 0,10829511 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04199474 0,10817916 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04199474 0,10806346 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04199474 0,10794801 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04199474 0,1078328 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04199474 0,10771784 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04199474 0,10760313 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04199474 0,10748865 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04199474 0,10737443 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04199474 0,10726044 ! regulation of meiosis GO:0040020 12 7 0,000 0,04199474 0,1071467 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04199474 0,10703319 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04199474 0,10691993 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04199474 0,10680691 GO:0002714|positive regulation of B cell mediated immunity, ! transcription termination GO:0006353 13 7 0,000 0,04199474 0,10669412 ! response to tumor cell GO:0002347 13 7 0,000 0,04199474 0,10658158 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04199474 0,10646927 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04199474 0,1063572 ! anaphase GO:0051322 17 7 0,000 0,04199474 0,10624536 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04199474 0,10613376 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04199474 0,10602239 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04199474 0,10591125 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04199474 0,10580035 ! diuresis GO:0030146 12 7 0,000 0,04199474 0,10568968 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04199474 0,10557924 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04199474 0,10546903 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04199474 0,10535906 ! antibiotic transport GO:0042891 9 7 0,000 0,04199474 0,10524931 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04199474 0,10513979 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04199474 0,10503049 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04199474 0,10492143 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04199474 0,10481259 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04199474 0,10470397 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04199474 0,10459559 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04199474 0,10448742 ! lymph node development GO:0048535 10 7 0,000 0,04199474 0,10437948 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04199474 0,10427176 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04199474 0,10416426 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04199474 0,10405699 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04199474 0,10394993 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04199474 0,1038431 ! adult feeding behavior GO:0008343 9 7 0,000 0,04199474 0,10373648 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04199474 0,10363009 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04199474 0,10352391 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04199474 0,10341795 ! muscle adaptation GO:0043500 14 7 0,000 0,04199474 0,1033122 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04199474 0,10320668 ! retina homeostasis GO:0001895 12 7 0,000 0,04199474 0,10310136 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04199474 0,10299626 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04199474 0,10289138 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04199474 0,10278671 ! protein prenylation GO:0018342 18 7 0,000 0,04199474 0,10268225 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04199474 0,10257801 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04199474 0,10247397 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04199474 0,10237015 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04317829 0,10514875 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04317829 0,10504244 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04463175 0,10846869 GO:0010952|positive regulation of peptidase activity, ! sulfur compound biosynthetic process GO:0044272 93 55 1,000 0,04463175 0,10835923 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04463175 0,10825 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04463175 0,10814099 ! aging GO:0007568 103 55 1,000 0,04463175 0,10803219 ! heart morphogenesis GO:0003007 97 55 1,000 0,04463175 0,10792362 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04463175 0,10781526 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04610317 0,111258 ! glycosaminoglycan metabolic process GO:0030203 91 56 1,000 0,04610317 0,11114652 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,04759227 0,11462162 ! muscle fiber development GO:0048747 112 57 1,000 0,04759227 0,114507 ! lipid modification GO:0030258 97 57 1,000 0,04759227 0,1143926 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04759227 0,11427844 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,04759227 0,1141645 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04784904 0,11466612 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04784904 0,11455202 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04784904 0,11443815 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04784904 0,11432451 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04784904 0,11421109 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04784904 0,1140979 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04784904 0,11398493 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04784904 0,11387219 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04784904 0,11375966 ! meiotic prophase I GO:0007128 13 8 0,000 0,04784904 0,11364736 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04784904 0,11353529 ! oligopeptide transport GO:0006857 15 8 0,000 0,04784904 0,11342343 ! UTP metabolic process GO:0046051 8 8 0,000 0,04784904 0,11331179 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04784904 0,11320037 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04784904 0,11308918 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04784904 0,1129782 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04784904 0,11286743 ! succinate metabolic process GO:0006105 14 8 0,000 0,04784904 0,11275689 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04784904 0,11264656 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04784904 0,11253644 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04784904 0,11242654 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04784904 0,11231686 ! reflex GO:0060004 16 8 0,000 0,04784904 0,11220739 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04784904 0,11209813 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04784904 0,11198909 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04784904 0,11188025 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04784904 0,11177163 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04784904 0,11166322 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04784904 0,11155502 ! pigment granule organization GO:0048753 16 8 0,000 0,04784904 0,11144703 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04784904 0,11133925 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04784904 0,11123167 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04784904 0,11112431 ! histidine metabolic process GO:0006547 16 8 0,000 0,04784904 0,11101715 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04784904 0,11091019 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04784904 0,11080345 ! glycine catabolic process GO:0006546 13 8 0,000 0,04784904 0,1106969 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04784904 0,11059057 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04784904 0,11048443 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04784904 0,11037851 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04784904 0,11027278 ! melanin metabolic process GO:0006582 15 8 0,000 0,04784904 0,11016725 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04784904 0,11006193 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04784904 0,10995681 ! macrophage activation GO:0042116 12 8 0,000 0,04784904 0,10985189 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04784904 0,10974717 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04784904 0,10964265 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04784904 0,10953833 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04784904 0,1094342 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04784904 0,10933028 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04784904 0,10922655 ! osteoblast development GO:0002076 16 8 0,000 0,04784904 0,10912301 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04784904 0,10901968 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04784904 0,10891654 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04784904 0,10881359 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04784904 0,10871084 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04784904 0,10860828 ! response to UV-B GO:0010224 16 8 0,000 0,04784904 0,10850592 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04784904 0,10840375 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04784904 0,10830177 ! intermediate filament organization GO:0045109 12 8 0,000 0,04784904 0,10819998 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04784904 0,10809839 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04784904 0,10799698 ! cellular extravasation GO:0045123 12 8 0,000 0,04784904 0,10789576 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04784904 0,10779474 ! response to antibiotic GO:0046677 11 8 0,000 0,04784904 0,1076939 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04784904 0,10759325 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04784904 0,10749279 ! DNA topological change GO:0006265 12 8 0,000 0,04784904 0,10739252 ! response to tropane GO:0014073 15 8 0,000 0,04784904 0,10729243 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04784904 0,10719253 ! melanosome transport GO:0032402 13 8 0,000 0,04784904 0,10709282 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04784904 0,10699329 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04784904 0,10689395 ! mast cell activation GO:0045576 14 8 0,000 0,04784904 0,10679479 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04784904 0,10669581 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04784904 0,10659702 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04784904 0,10649841 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04784904 0,10639998 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04784904 0,10630174 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04784904 0,10620367 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04784904 0,10610579 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04784904 0,10600809 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04784904 0,10591056 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04784904 0,10581322 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04784904 0,10571605 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04784904 0,10561906 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04784904 0,10552226 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04784904 0,10542562 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04784904 0,10532917 ! hormone catabolic process GO:0042447 17 8 0,000 0,04784904 0,10523289 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04784904 0,10513679 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04784904 0,10504086 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04784904 0,10494511 ! ATP catabolic process GO:0006200 11 8 0,000 0,04784904 0,10484953 ! blastocyst growth GO:0001832 19 8 0,000 0,04784904 0,10475412 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04784904 0,10465889 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04784904 0,10456383 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04784904 0,10446895 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04784904 0,10437423 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04784904 0,10427969 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04784904 0,10418532 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04784904 0,10409112 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04784904 0,10399709 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04784904 0,10390323 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04784904 0,10380954 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04784904 0,10371602 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04784904 0,10362266 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04784904 0,10352948 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04784904 0,10343646 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,04909878 0,10604279 ! adult behavior GO:0030534 99 58 1,000 0,04909878 0,10594768 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04909878 0,10585275 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,05062244 0,10903992 ! DNA catabolic process GO:0006308 86 59 1,000 0,05062244 0,10894239 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05366775 0,11539287 ! axon extension GO:0048675 15 9 0,000 0,05366775 0,11528984 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05366775 0,11518699 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05366775 0,11508433 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05366775 0,11498185 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05366775 0,11487955 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05366775 0,11477744 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05366775 0,1146755 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05366775 0,11457375 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05366775 0,11447218 ! phosphate transport GO:0006817 19 9 0,000 0,05366775 0,11437078 ! reproductive behavior GO:0019098 19 9 0,000 0,05366775 0,11426957 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05366775 0,11416854 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05366775 0,11406768 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05366775 0,113967 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05366775 0,1138665 ! GTP metabolic process GO:0046039 9 9 0,000 0,05366775 0,11376618 ! RNA methylation GO:0001510 15 9 0,000 0,05366775 0,11366604 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05366775 0,11356607 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05366775 0,11346627 ! artery development GO:0060840 24 9 0,000 0,05366775 0,11336665 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05366775 0,11326721 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05366775 0,11316794 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05366775 0,11306884 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05366775 0,11296992 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05366775 0,11287117 ! chemosensory behavior GO:0007635 20 9 0,000 0,05366775 0,11277259 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05366775 0,11267418 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05366775 0,11257595 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05366775 0,11247789 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05366775 0,11238 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05366775 0,11228227 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05366775 0,11218472 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05366775 0,11208734 ! protein targeting to ER GO:0045047 22 9 0,000 0,05366775 0,11199013 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05366775 0,11189308 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05366775 0,1117962 ! T cell selection GO:0045058 23 9 0,000 0,05366775 0,11169949 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05366775 0,11160295 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05366775 0,11150658 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05366775 0,11141037 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05366775 0,11131432 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05366775 0,11121845 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05366775 0,11112273 ! mannose metabolic process GO:0006013 13 9 0,000 0,05366775 0,11102718 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05366775 0,1109318 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05366775 0,11083658 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05366775 0,11074152 ! receptor clustering GO:0043113 18 9 0,000 0,05366775 0,11064663 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05366775 0,1105519 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05366775 0,11045733 ! ruffle organization GO:0031529 15 9 0,000 0,05366775 0,11036292 ! retinol metabolic process GO:0042572 18 9 0,000 0,05366775 0,11026867 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05366775 0,11017459 ! behavioral fear response GO:0001662 22 9 0,000 0,05366775 0,11008066 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05366775 0,1099869 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05366775 0,10989329 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05366775 0,10979984 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05366775 0,10970656 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05366775 0,10961343 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05366775 0,10952045 ! segment specification GO:0007379 13 9 0,000 0,05366775 0,10942764 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05366775 0,10933498 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05366775 0,10924248 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05366775 0,10915014 ! response to amine stimulus GO:0014075 13 9 0,000 0,05366775 0,10905795 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05366775 0,10896592 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05366775 0,10887404 ! erythrocyte development GO:0048821 15 9 0,000 0,05366775 0,10878232 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05366775 0,10869075 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05366775 0,10859934 ! renal water homeostasis GO:0003091 14 9 0,000 0,05366775 0,10850808 ! postreplication repair GO:0006301 22 9 0,000 0,05366775 0,10841697 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05366775 0,10832602 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05366775 0,10823522 ! icosanoid secretion GO:0032309 15 9 0,000 0,05366775 0,10814457 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05366775 0,10805407 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05366775 0,10796373 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05366775 0,10787353 ! regulation of cell division GO:0051302 15 9 0,000 0,05366775 0,10778349 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05366775 0,10769359 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05366775 0,10760385 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05366775 0,10751425 ! sterol catabolic process GO:0016127 11 9 0,000 0,05366775 0,10742481 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05366775 0,10733551 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05366775 0,10724636 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05366775 0,10715736 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05366775 0,1070685 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05366775 0,1069798 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05366775 0,10689124 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05366775 0,10680283 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05366775 0,10671456 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05366775 0,10662644 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05366775 0,10653846 ! purine base metabolic process GO:0006144 21 9 0,000 0,05366775 0,10645063 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05366775 0,10636295 ! pigment granule transport GO:0051904 17 9 0,000 0,05366775 0,1062754 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05366775 0,10618801 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05366775 0,10610075 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05366775 0,10601364 ! mitochondrion localization GO:0051646 15 9 0,000 0,05366775 0,10592667 ! sphingolipid metabolic process GO:0006665 107 61 1,000 0,05372016 0,1059432 ! ear development GO:0043583 103 62 1,000 0,0552937 0,10895711 ! detection of external stimulus GO:0009581 91 63 1,000 0,05688334 0,11199781 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,05848885 0,11506474 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0594511 0,11686222 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0594511 0,11676682 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0594511 0,11667158 ! synapsis GO:0007129 13 10 0,000 0,0594511 0,11657649 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0594511 0,11648156 ! N-glycan processing GO:0006491 20 10 0,000 0,0594511 0,11638678 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0594511 0,11629216 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0594511 0,11619769 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0594511 0,11610338 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0594511 0,11600921 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0594511 0,1159152 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0594511 0,11582134 ! androgen metabolic process GO:0008209 17 10 0,000 0,0594511 0,11572764 ! phospholipid efflux GO:0033700 16 10 0,000 0,0594511 0,11563408 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0594511 0,11554068 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0594511 0,11544742 ! pathogenesis GO:0009405 13 10 0,000 0,0594511 0,11535432 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0594511 0,11526137 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0594511 0,11516857 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0594511 0,11507591 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0594511 0,11498341 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0594511 0,11489105 ! endoderm development GO:0007492 16 10 0,000 0,0594511 0,11479884 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0594511 0,11470678 ! arginine catabolic process GO:0006527 13 10 0,000 0,0594511 0,11461487 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0594511 0,11452311 ! proline metabolic process GO:0006560 13 10 0,000 0,0594511 0,11443149 ! L-serine metabolic process GO:0006563 18 10 0,000 0,0594511 0,11434001 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0594511 0,11424869 ! V(D)J recombination GO:0033151 28 10 0,000 0,0594511 0,11415751 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0594511 0,11406647 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0594511 0,11397558 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0594511 0,11388484 ! B cell proliferation GO:0042100 18 10 0,000 0,0594511 0,11379424 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0594511 0,11370378 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0594511 0,11361347 ! multicellular organism growth GO:0035264 18 10 0,000 0,0594511 0,1135233 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0594511 0,11343327 ! epithelial cell development GO:0002064 20 10 0,000 0,0594511 0,11334339 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0594511 0,11325365 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0594511 0,11316405 ! macroautophagy GO:0016236 17 10 0,000 0,0594511 0,11307459 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0594511 0,11298528 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0594511 0,1128961 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0594511 0,11280707 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0594511 0,11271817 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0594511 0,11262942 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0594511 0,1125408 ! brain morphogenesis GO:0048854 23 10 0,000 0,0594511 0,11245233 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0594511 0,11236399 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0594511 0,11227579 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0594511 0,11218773 ! response to dsRNA GO:0043331 20 10 0,000 0,0594511 0,11209981 ! DNA ligation GO:0006266 19 10 0,000 0,0594511 0,11201203 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0594511 0,11192438 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0594511 0,11183687 ! melanosome localization GO:0032400 16 10 0,000 0,0594511 0,1117495 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0594511 0,11166226 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0594511 0,11157516 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0594511 0,1114882 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0594511 0,11140137 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0594511 0,11131468 ! mRNA cleavage GO:0006379 17 10 0,000 0,0594511 0,11122812 ! protein sumoylation GO:0016925 15 10 0,000 0,0594511 0,11114169 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0594511 0,1110554 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0594511 0,11096925 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0594511 0,11088322 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0594511 0,11079733 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0594511 0,11071158 ! salivary gland development GO:0007431 27 10 0,000 0,0594511 0,11062595 ! prophase GO:0051324 15 10 0,000 0,0594511 0,11054046 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0594511 0,1104551 ! apical protein localization GO:0045176 15 10 0,000 0,0594511 0,11036988 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0594511 0,11028478 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0594511 0,11019981 ! midbrain development GO:0030901 13 10 0,000 0,0594511 0,11011498 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0594511 0,11003028 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0594511 0,1099457 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0594511 0,10986126 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0594511 0,10977694 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0594511 0,10969276 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0594511 0,1096087 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0594511 0,10952478 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,0594511 0,10944098 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,0594511 0,10935731 ! oocyte development GO:0048599 17 10 0,000 0,0594511 0,10927377 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0594511 0,10919035 ! blastocyst formation GO:0001825 17 10 0,000 0,0594511 0,10910706 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0594511 0,1090239 ! activation of innate immune response GO:0002218 12 10 0,000 0,0594511 0,10894087 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0594511 0,10885796 ! response to nicotine GO:0035094 20 10 0,000 0,0594511 0,10877518 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0594511 0,10869252 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0594511 0,10860999 ! aminoglycan metabolic process GO:0006022 102 65 1,000 0,06010996 0,10973033 ! germ cell development GO:0007281 118 65 1,000 0,06010996 0,10964713 ! actin filament organization GO:0007015 148 66 1,000 0,06174643 0,11254691 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,06174643 0,11246171 ! developmental maturation GO:0021700 116 66 1,000 0,06174643 0,11237664 ! cell projection assembly GO:0030031 120 66 1,000 0,06174643 0,1122917 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,06339802 0,11520818 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,06339802 0,11512123 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06339802 0,11503441 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,06339802 0,11494773 ! adaptive immune response GO:0002250 119 67 1,000 0,06339802 0,11486117 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,06506447 0,11779166 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,06506447 0,1177031 ! membrane lipid metabolic process GO:0006643 117 68 1,000 0,06506447 0,11761467 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0651993 0,11776991 ! respiratory burst GO:0045730 17 11 0,000 0,0651993 0,11768156 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0651993 0,11759335 ! neuron fate specification GO:0048665 17 11 0,000 0,0651993 0,11750526 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0651993 0,11741731 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0651993 0,11732949 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0651993 0,1172418 ! thyroid gland development GO:0030878 26 11 0,000 0,0651993 0,11715424 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0651993 0,11706681 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0651993 0,11697951 ! response to pain GO:0048265 24 11 0,000 0,0651993 0,11689234 ! T cell proliferation GO:0042098 26 11 0,000 0,0651993 0,1168053 ! bone resorption GO:0045453 16 11 0,000 0,0651993 0,1167184 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0651993 0,11663162 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0651993 0,11654497 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0651993 0,11645844 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0651993 0,11637205 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0651993 0,11628578 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0651993 0,11619965 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0651993 0,11611364 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0651993 0,11602775 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0651993 0,115942 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,0651993 0,11585637 ! lipid digestion GO:0044241 18 11 0,000 0,0651993 0,11577087 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0651993 0,11568549 ! UV protection GO:0009650 19 11 0,000 0,0651993 0,11560024 ! adult heart development GO:0007512 14 11 0,000 0,0651993 0,11551511 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0651993 0,11543011 ! temperature homeostasis GO:0001659 17 11 0,000 0,0651993 0,11534524 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0651993 0,11526049 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0651993 0,11517586 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0651993 0,11509136 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0651993 0,11500698 ! regulation of organ growth GO:0046620 13 11 0,000 0,0651993 0,11492273 ! pigment granule localization GO:0051875 20 11 0,000 0,0651993 0,1148386 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0651993 0,11475459 ! vasoconstriction GO:0042310 18 11 0,000 0,0651993 0,1146707 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0651993 0,11458694 ! embryonic axis specification GO:0000578 18 11 0,000 0,0651993 0,1145033 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0651993 0,11441978 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0651993 0,11433639 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0651993 0,11425311 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0651993 0,11416996 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0651993 0,11408693 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0651993 0,11400401 ! zymogen activation GO:0031638 15 11 0,000 0,0651993 0,11392122 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0651993 0,11383855 ! nucleosome positioning GO:0016584 15 11 0,000 0,0651993 0,113756 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0651993 0,11367357 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0651993 0,11359125 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0651993 0,11350906 ! acid secretion GO:0046717 18 11 0,000 0,0651993 0,11342699 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0651993 0,11334503 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0651993 0,11326319 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0651993 0,11318147 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0651993 0,11309987 ! oocyte differentiation GO:0009994 18 11 0,000 0,0651993 0,11301839 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0651993 0,11293702 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0651993 0,11285577 ! cholesterol efflux GO:0033344 19 11 0,000 0,0651993 0,11277464 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0651993 0,11269362 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0651993 0,11261272 ! germ cell migration GO:0008354 25 11 0,000 0,0651993 0,11253194 ! embryonic gut development GO:0048566 15 11 0,000 0,0651993 0,11245127 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0651993 0,11237072 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0651993 0,11229028 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0651993 0,11220996 ! defense response to fungus GO:0050832 13 11 0,000 0,0651993 0,11212975 ! developmental induction GO:0031128 19 11 0,000 0,0651993 0,11204966 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0651993 0,11196968 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0651993 0,11188982 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0651993 0,11181007 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0651993 0,11173043 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0651993 0,11165091 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0651993 0,1115715 ! nucleus localization GO:0051647 19 11 0,000 0,0651993 0,1114922 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0651993 0,11141301 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06674555 0,11397431 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,06674555 0,11389348 ! humoral immune response GO:0006959 109 71 1,000 0,07015065 0,11961904 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07015065 0,11953433 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07091256 0,12074708 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07091256 0,12066168 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07091256 0,12057641 ! virus-host interaction GO:0019048 29 12 0,000 0,07091256 0,12049126 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07091256 0,12040622 ! cartilage condensation GO:0001502 20 12 0,000 0,07091256 0,12032131 ! mating GO:0007618 17 12 0,000 0,07091256 0,12023652 ! protein complex disassembly GO:0043241 27 12 0,000 0,07091256 0,12015185 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07091256 0,12006729 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07091256 0,11998286 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,07091256 0,11989854 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07091256 0,11981434 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07091256 0,11973026 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07091256 0,1196463 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07091256 0,11956245 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07091256 0,11947873 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07091256 0,11939512 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07091256 0,11931162 ! drug transport GO:0015893 16 12 0,000 0,07091256 0,11922825 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07091256 0,11914499 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07091256 0,11906184 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07091256 0,11897881 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07091256 0,1188959 ! focal adhesion formation GO:0048041 35 12 0,000 0,07091256 0,11881311 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07091256 0,11873042 ! forebrain cell migration GO:0021885 21 12 0,000 0,07091256 0,11864786 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07091256 0,11856541 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07091256 0,11848307 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07091256 0,11840085 ! entry into host cell GO:0030260 32 12 0,000 0,07091256 0,11831874 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07091256 0,11823674 ! monoamine transport GO:0015844 18 12 0,000 0,07091256 0,11815486 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07091256 0,11807309 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07091256 0,11799144 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07091256 0,1179099 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07091256 0,11782847 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07091256 0,11774715 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07091256 0,11766595 ! protein homotetramerization GO:0051289 21 12 0,000 0,07091256 0,11758485 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07091256 0,11750387 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07091256 0,117423 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07091256 0,11734224 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07091256 0,11726159 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07091256 0,11718106 ! cranial nerve development GO:0021545 20 12 0,000 0,07091256 0,11710063 ! fucose catabolic process GO:0019317 22 12 0,000 0,07091256 0,11702032 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07091256 0,11694011 ! histone methylation GO:0016571 26 12 0,000 0,07091256 0,11686001 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07091256 0,11678003 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07091256 0,11670015 ! gland morphogenesis GO:0022612 29 12 0,000 0,07091256 0,11662038 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07091256 0,11654072 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07091256 0,11646117 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07091256 0,11638173 ! spleen development GO:0048536 22 12 0,000 0,07091256 0,1163024 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07091256 0,11622317 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07091256 0,11614406 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07091256 0,11606505 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07091256 0,11598615 ! response to cold GO:0009409 17 12 0,000 0,07091256 0,11590735 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07091256 0,11582866 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07091256 0,11575008 ! acute inflammatory response GO:0002526 113 72 1,000 0,0718742 0,11724022 ! regulation of caspase activity GO:0043281 122 72 1,000 0,0718742 0,11716079 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0718742 0,11708146 ! carbohydrate transport GO:0008643 110 72 1,000 0,0718742 0,11700225 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,0718742 0,11692314 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,0718742 0,11684413 ! learning or memory GO:0007611 147 73 1,000 0,07361143 0,11958751 ! regulation of blood pressure GO:0008217 125 73 1,000 0,07361143 0,11950682 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,07536212 0,12226653 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 1,000 0,07536212 0,12218414 ! exocytosis GO:0006887 133 74 1,000 0,07536212 0,12210186 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,07536212 0,12201969 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07659109 0,12392613 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07659109 0,12384285 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07659109 0,12375968 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07659109 0,12367662 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07659109 0,12359367 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07659109 0,12351083 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07659109 0,1234281 ! organelle fusion GO:0048284 32 13 0,000 0,07659109 0,12334549 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07659109 0,12326298 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07659109 0,12318059 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07659109 0,1230983 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07659109 0,12301613 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07659109 0,12293406 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07659109 0,12285211 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07659109 0,12277026 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07659109 0,12268852 ! methionine metabolic process GO:0006555 27 13 0,000 0,07659109 0,12260689 ! plasma membrane organization GO:0007009 24 13 0,000 0,07659109 0,12252537 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07659109 0,12244396 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07659109 0,12236266 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07659109 0,12228146 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07659109 0,12220037 ! response to X-ray GO:0010165 25 13 0,000 0,07659109 0,12211939 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07659109 0,12203852 ! exocrine system development GO:0035272 32 13 0,000 0,07659109 0,12195775 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07659109 0,12187709 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07659109 0,12179654 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07659109 0,12171609 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07659109 0,12163575 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07659109 0,12155551 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07659109 0,12147538 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07659109 0,12139536 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07659109 0,12131544 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07659109 0,12123563 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07659109 0,12115592 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07659109 0,12107632 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07659109 0,12099682 ! ribosome assembly GO:0042255 17 13 0,000 0,07659109 0,12091743 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07659109 0,12083814 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07659109 0,12075895 ! chromatin silencing GO:0006342 26 13 0,000 0,07659109 0,12067987 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07659109 0,12060089 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07659109 0,12052201 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07659109 0,12044324 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07659109 0,12036457 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07659109 0,120286 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07659109 0,12020754 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07659109 0,12012918 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07659109 0,12005092 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07659109 0,11997276 ! embryonic placenta development GO:0001892 23 13 0,000 0,07659109 0,1198947 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07659109 0,11981675 ! insulin secretion GO:0030073 23 13 0,000 0,07659109 0,11973889 ! actin filament polymerization GO:0030041 24 13 0,000 0,07659109 0,11966114 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07659109 0,11958349 ! acrosome reaction GO:0007340 18 13 0,000 0,07659109 0,11950594 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07712604 0,12026264 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,07712604 0,12018475 ! defense response to bacterium GO:0042742 89 76 1,000 0,07890297 0,12287414 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,07890297 0,12279466 ! regulation of catabolic process GO:0009894 161 76 1,000 0,07890297 0,12271529 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,08069268 0,1254177 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,08069268 0,12533673 ! rRNA transcription GO:0009303 25 14 0,000 0,0822351 0,12765009 ! lactation GO:0007595 26 14 0,000 0,0822351 0,12756779 ! reproductive cellular process GO:0048610 20 14 0,000 0,0822351 0,1274856 ! tRNA modification GO:0006400 20 14 0,000 0,0822351 0,12740351 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0822351 0,12732152 ! regulation of S phase GO:0033261 23 14 0,000 0,0822351 0,12723964 ! water transport GO:0006833 21 14 0,000 0,0822351 0,12715787 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0822351 0,1270762 ! non-recombinational repair GO:0000726 25 14 0,000 0,0822351 0,12699464 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0822351 0,12691318 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0822351 0,12683182 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0822351 0,12675057 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0822351 0,12666943 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0822351 0,12658838 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0822351 0,12650745 ! palate development GO:0060021 31 14 0,000 0,0822351 0,12642661 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0822351 0,12634588 ! arginine metabolic process GO:0006525 17 14 0,000 0,0822351 0,12626525 ! regulation of heart rate GO:0002027 24 14 0,000 0,0822351 0,12618472 ! organic alcohol transport GO:0015850 29 14 0,000 0,0822351 0,1261043 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0822351 0,12602398 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0822351 0,12594376 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0822351 0,12586364 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0822351 0,12578363 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0822351 0,12570371 ! L-amino acid transport GO:0015807 30 14 0,000 0,0822351 0,1256239 ! bone mineralization GO:0030282 17 14 0,000 0,0822351 0,12554419 ! stem cell development GO:0048864 43 14 0,000 0,0822351 0,12546458 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0822351 0,12538507 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0822351 0,12530566 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0822351 0,12522636 ! cerebellum development GO:0021549 21 14 0,000 0,0822351 0,12514715 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0822351 0,12506804 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0822351 0,12498904 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0822351 0,12491013 ! cofactor transport GO:0051181 26 14 0,000 0,0822351 0,12483132 ! NADP metabolic process GO:0006739 24 14 0,000 0,0822351 0,12475261 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0822351 0,124674 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0822351 0,12459549 ! intestinal absorption GO:0050892 25 14 0,000 0,0822351 0,12451708 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0822351 0,12443877 ! oxygen transport GO:0015671 21 14 0,000 0,0822351 0,12436056 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0822351 0,12428244 ! male genitalia development GO:0030539 24 14 0,000 0,0822351 0,12420442 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0822351 0,1241265 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,08249496 0,12444067 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,08249496 0,1243627 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,08430958 0,12701869 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,08430958 0,1269392 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,08430958 0,12685982 ! response to metal ion GO:0010038 140 80 1,000 0,08613633 0,1295275 ! muscle cell differentiation GO:0042692 159 80 1,000 0,08613633 0,1294466 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,08613633 0,12936579 ! protein import into nucleus GO:0006606 158 80 1,000 0,08613633 0,12928509 ! inorganic anion transport GO:0015698 138 80 1,000 0,08613633 0,12920449 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0878448 0,1316851 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0878448 0,1316031 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0878448 0,13152121 ! superoxide anion generation GO:0042554 20 15 0,000 0,0878448 0,13143941 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0878448 0,13135772 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0878448 0,13127614 ! copper ion transport GO:0006825 20 15 0,000 0,0878448 0,13119465 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0878448 0,13111326 ! response to cAMP GO:0051591 22 15 0,000 0,0878448 0,13103198 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0878448 0,13095079 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0878448 0,13086971 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0878448 0,13078872 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0878448 0,13070784 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0878448 0,13062706 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0878448 0,13054637 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0878448 0,13046579 ! pituitary gland development GO:0021983 29 15 0,000 0,0878448 0,1303853 ! vesicle coating GO:0006901 33 15 0,000 0,0878448 0,13030492 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0878448 0,13022463 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0878448 0,13014444 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0878448 0,13006436 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0878448 0,12998437 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0878448 0,12990447 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0878448 0,12982468 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0878448 0,12974498 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0878448 0,12966539 ! histone deacetylation GO:0016575 20 15 0,000 0,0878448 0,12958588 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0878448 0,12950648 ! tissue regeneration GO:0042246 26 15 0,000 0,0878448 0,12942718 ! water homeostasis GO:0030104 27 15 0,000 0,0878448 0,12934797 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0878448 0,12926885 ! muscle maintenance GO:0046716 26 15 0,000 0,0878448 0,12918984 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0878448 0,12911092 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0878448 0,1290321 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0878448 0,12895337 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0878448 0,12887474 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0878448 0,12879621 ! detection of bacterium GO:0016045 18 15 0,000 0,0878448 0,12871777 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0878448 0,12863943 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0878448 0,12856118 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0878448 0,12848303 ! peptide hormone processing GO:0016486 23 15 0,000 0,0878448 0,12840497 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08797499 0,1285172 ! nuclear import GO:0051170 161 81 1,000 0,08797499 0,12843922 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09342039 0,13630652 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,09342039 0,13622391 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09342039 0,1361414 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09342039 0,13605899 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09342039 0,13597668 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09342039 0,13589447 ! bone remodeling GO:0046849 27 16 0,000 0,09342039 0,13581236 ! filopodium assembly GO:0046847 32 16 0,000 0,09342039 0,13573035 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09342039 0,13564844 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09342039 0,13556662 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09342039 0,13548491 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09342039 0,13540329 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09342039 0,13532177 ! startle response GO:0001964 28 16 0,000 0,09342039 0,13524035 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09342039 0,13515903 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09342039 0,1350778 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09342039 0,13499667 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09342039 0,13491564 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09342039 0,13483471 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09342039 0,13475387 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09342039 0,13467313 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09342039 0,13459249 ! response to osmotic stress GO:0006970 25 16 0,000 0,09342039 0,13451194 ! lysosomal transport GO:0007041 26 16 0,000 0,09342039 0,13443149 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09342039 0,13435114 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09342039 0,13427088 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09342039 0,13419072 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09342039 0,13411066 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09342039 0,13403069 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09342039 0,13395081 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,09342039 0,13387103 ! DNA replication initiation GO:0006270 27 16 0,000 0,09342039 0,13379134 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09342039 0,13371175 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09342039 0,13363226 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09342039 0,13355286 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09342039 0,13347355 ! biomineral formation GO:0031214 20 16 0,000 0,09342039 0,13339434 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09342039 0,13331522 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09342039 0,13323619 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09342039 0,13315726 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09342039 0,13307842 ! defense response to virus GO:0051607 37 16 0,000 0,09342039 0,13299968 ! negative regulation of growth GO:0045926 155 84 1,000 0,09356036 0,13312018 ! regulation of ligase activity GO:0051340 142 84 1,000 0,09356036 0,1330415 ! response to inorganic substance GO:0010035 153 86 1,000 0,09733969 0,13833389 ! tube morphogenesis GO:0035239 176 86 1,000 0,09733969 0,13825223 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09896209 0,14047362 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09896209 0,14039079 ! metencephalon development GO:0022037 30 17 0,000 0,09896209 0,14030806 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09896209 0,14022543 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,09896209 0,1401429 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09896209 0,14006046 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09896209 0,13997812 ! signal complex assembly GO:0007172 41 17 0,000 0,09896209 0,13989588 ! endothelial cell migration GO:0043542 28 17 0,000 0,09896209 0,13981373 ! inositol metabolic process GO:0006020 28 17 0,000 0,09896209 0,13973168 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09896209 0,13964973 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09896209 0,13956787 ! glial cell development GO:0021782 27 17 0,000 0,09896209 0,13948611 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09896209 0,13940444 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09896209 0,13932287 ! heart looping GO:0001947 30 17 0,000 0,09896209 0,13924139 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09896209 0,13916001 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09896209 0,13907873 ! myoblast differentiation GO:0045445 45 17 0,000 0,09896209 0,13899754 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09896209 0,13891644 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09896209 0,13883544 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09896209 0,13875454 ! glycine metabolic process GO:0006544 28 17 0,000 0,09896209 0,13867372 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09896209 0,13859301 ! NAD metabolic process GO:0019674 29 17 0,000 0,09896209 0,13851238 ! membrane budding GO:0006900 37 17 0,000 0,09896209 0,13843185 ! DNA integration GO:0015074 29 17 0,000 0,09896209 0,13835141 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,09896209 0,13827107 ! regulation of protein binding GO:0043393 33 17 0,000 0,09896209 0,13819082 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09896209 0,13811066 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09896209 0,1380306 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09896209 0,13795063 ! genitalia development GO:0048806 30 17 0,000 0,09896209 0,13787075 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09896209 0,13779096 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09896209 0,13771127 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09896209 0,13763167 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09896209 0,13755216 ! steroid catabolic process GO:0006706 31 17 0,000 0,09896209 0,13747274 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09896209 0,13739341 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09896209 0,13731418 ! gas transport GO:0015669 25 17 0,000 0,09896209 0,13723503 ! organic cation transport GO:0015695 31 17 0,000 0,09896209 0,13715598 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09896209 0,13707702 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09896209 0,13699815 ! microspike assembly GO:0030035 36 17 0,000 0,09896209 0,13691937 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09896209 0,13684068 ! protein localization in nucleus GO:0034504 176 87 1,000 0,09924546 0,13715369 ! regulation of protein transport GO:0051223 154 87 1,000 0,09924546 0,13707496 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,10116171 0,13964147 ! gland development GO:0048732 206 88 1,000 0,10116171 0,1395614 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10447009 0,14404301 ! neuron maturation GO:0042551 42 18 0,000 0,10447009 0,14396051 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10447009 0,1438781 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10447009 0,14379579 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10447009 0,14371358 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10447009 0,14363145 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10447009 0,14354943 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10447009 0,14346749 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10447009 0,14338565 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10447009 0,1433039 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10447009 0,14322225 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,10447009 0,14314069 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10447009 0,14305922 ! response to retinoic acid GO:0032526 26 18 0,000 0,10447009 0,14297784 ! response to fungus GO:0009620 21 18 0,000 0,10447009 0,14289656 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10447009 0,14281537 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10447009 0,14273427 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10447009 0,14265326 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10447009 0,14257235 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10447009 0,14249152 ! vitamin transport GO:0051180 27 18 0,000 0,10447009 0,14241079 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10447009 0,14233015 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10447009 0,1422496 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10447009 0,14216914 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10447009 0,14208878 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,10447009 0,1420085 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,10447009 0,14192832 ! nerve development GO:0021675 28 18 0,000 0,10447009 0,14184822 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10447009 0,14176822 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,10697136 0,14508066 ! protein secretion GO:0009306 39 19 0,000 0,10994461 0,14902915 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10994461 0,14894523 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10994461 0,14886142 ! skin development GO:0043588 36 19 0,000 0,10994461 0,14877769 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10994461 0,14869406 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10994461 0,14861053 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10994461 0,14852708 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10994461 0,14844373 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10994461 0,14836048 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10994461 0,14827732 ! cerebral cortex development GO:0021987 36 19 0,000 0,10994461 0,14819425 ! pigmentation during development GO:0048066 41 19 0,000 0,10994461 0,14811127 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10994461 0,14802839 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10994461 0,1479456 ! heme metabolic process GO:0042168 36 19 0,000 0,10994461 0,1478629 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10994461 0,1477803 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10994461 0,14769779 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10994461 0,14761537 ! protein export from nucleus GO:0006611 36 19 0,000 0,10994461 0,14753304 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10994461 0,1474508 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10994461 0,14736865 ! visual learning GO:0008542 36 19 0,000 0,10994461 0,1472866 ! cellular pigmentation GO:0033059 36 19 0,000 0,10994461 0,14720464 ! G1 phase GO:0051318 40 19 0,000 0,10994461 0,14712277 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10994461 0,14704099 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10994461 0,1469593 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10994461 0,1468777 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10994461 0,14679619 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10994461 0,14671477 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10994461 0,14663345 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10994461 0,14655221 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10994461 0,14647106 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10994461 0,14639 ! cilium assembly GO:0042384 37 19 0,000 0,10994461 0,14630904 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10994461 0,14622816 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,11089327 0,1474084 GO:0010498|proteasomal protein catabolic process, ! transcription initiation GO:0006352 153 94 1,000 0,1128683 0,14995093 ! regulation of T cell activation GO:0050863 158 94 1,000 0,1128683 0,14986817 ! forebrain development GO:0030900 188 95 1,000 0,11485247 0,15241866 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11538584 0,15304208 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,11538584 0,15295776 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11538584 0,15287353 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11538584 0,1527894 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11538584 0,15270536 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11538584 0,15262141 ! response to vitamin GO:0033273 31 20 0,000 0,11538584 0,15253755 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11538584 0,15245378 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,11538584 0,15237011 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11538584 0,15228653 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11538584 0,15220304 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11538584 0,15211964 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11538584 0,15203633 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11538584 0,15195311 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11538584 0,15186999 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,11538584 0,15178695 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11538584 0,15170401 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11538584 0,15162116 ! body fluid secretion GO:0007589 31 20 0,000 0,11538584 0,15153839 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11538584 0,15145572 ! peptide secretion GO:0002790 35 20 0,000 0,11538584 0,15137314 ! stem cell differentiation GO:0048863 53 20 0,000 0,11538584 0,15129065 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11538584 0,15120825 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11538584 0,15112593 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11538584 0,15104371 ! sensory perception of pain GO:0019233 30 20 0,000 0,11538584 0,15096158 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11538584 0,15087953 ! diencephalon development GO:0021536 34 20 0,000 0,11538584 0,15079758 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11538584 0,15071571 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11538584 0,15063393 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11538584 0,15055224 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11538584 0,15047064 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11538584 0,15038913 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11538584 0,15030771 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11538584 0,15022637 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11538584 0,15014513 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11538584 0,15006397 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11538584 0,1499829 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,11884747 0,15439904 ! protein ubiquitination GO:0016567 217 97 1,000 0,11884747 0,15431572 ! regulation of protein localization GO:0032880 176 97 1,000 0,11884747 0,15423248 ! regulation of cell killing GO:0031341 42 21 0,000 0,12079399 0,15667404 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12079399 0,15658962 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12079399 0,1565053 ! hormone secretion GO:0046879 38 21 0,000 0,12079399 0,15642107 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12079399 0,15633692 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,12079399 0,15625287 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12079399 0,15616891 ! axis specification GO:0009798 38 21 0,000 0,12079399 0,15608504 ! ovarian follicle development GO:0001541 35 21 0,000 0,12079399 0,15600126 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12079399 0,15591756 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12079399 0,15583396 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12079399 0,15575045 ! cell aging GO:0007569 44 21 0,000 0,12079399 0,15566703 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12079399 0,15558369 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12079399 0,15550045 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,12079399 0,15541729 ! cytolysis GO:0019835 24 21 0,000 0,12079399 0,15533423 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12079399 0,15525125 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12079399 0,15516836 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12079399 0,15508556 ! oogenesis GO:0048477 36 21 0,000 0,12079399 0,15500285 ! DNA modification GO:0006304 34 21 0,000 0,12079399 0,15492022 ! collagen fibril organization GO:0030199 59 21 0,000 0,12079399 0,15483769 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12079399 0,15475524 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12079399 0,15467288 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,12079399 0,15459061 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12079399 0,15450842 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12079399 0,15442632 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,12079399 0,15434431 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,12079399 0,15426239 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12079399 0,15418055 ! collagen catabolic process GO:0030574 28 21 0,000 0,12079399 0,1540988 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12079399 0,15401714 ! gut development GO:0048565 39 21 0,000 0,12079399 0,15393556 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,12287684 0,15650698 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12616925 0,16061546 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12616925 0,16053053 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12616925 0,16044568 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12616925 0,16036092 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12616925 0,16027625 ! regeneration GO:0031099 41 22 0,000 0,12616925 0,16019167 ! keratinization GO:0031424 28 22 0,000 0,12616925 0,16010719 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12616925 0,16002278 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12616925 0,15993847 ! sensory perception of taste GO:0050909 28 22 0,000 0,12616925 0,15985425 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12616925 0,15977012 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12616925 0,15968607 ! vacuolar transport GO:0007034 36 22 0,000 0,12616925 0,15960212 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12616925 0,15951825 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12616925 0,15943447 ! fucose metabolic process GO:0006004 39 22 0,000 0,12616925 0,15935077 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12616925 0,15926717 ! ureteric bud development GO:0001657 43 22 0,000 0,12616925 0,15918365 ! renal system process GO:0003014 41 22 0,000 0,12616925 0,15910022 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12616925 0,15901688 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12616925 0,15893362 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12616925 0,15885046 ! sarcomere organization GO:0045214 30 22 0,000 0,12616925 0,15876738 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12616925 0,15868438 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12616925 0,15860147 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12616925 0,15851865 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,12616925 0,15843592 ! protein stabilization GO:0050821 39 22 0,000 0,12616925 0,15835327 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,13151183 0,16497261 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,13151183 0,16488664 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,13151183 0,16480076 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13151183 0,16471497 ! gluconeogenesis GO:0006094 33 23 0,000 0,13151183 0,16462927 ! viral genome replication GO:0019079 41 23 0,000 0,13151183 0,16454366 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13151183 0,16445814 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13151183 0,16437271 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13151183 0,16428736 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13151183 0,16420211 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13151183 0,16411694 ! visual behavior GO:0007632 42 23 0,000 0,13151183 0,16403186 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,13151183 0,16394687 ! response to ethanol GO:0045471 46 23 0,000 0,13151183 0,16386197 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13151183 0,16377715 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13151183 0,16369243 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13151183 0,16360779 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13151183 0,16352324 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13151183 0,16343877 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13151183 0,1633544 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,13151183 0,1632701 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,13151183 0,1631859 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,13151183 0,16310179 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13151183 0,16301776 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13151183 0,16293381 ! fatty acid transport GO:0015908 44 23 0,000 0,13151183 0,16284996 ! platelet activation GO:0030168 37 23 0,000 0,13151183 0,16276618 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13151183 0,1626825 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13151183 0,1625989 ! hormone transport GO:0009914 40 23 0,000 0,13151183 0,16251539 ! cell-cell recognition GO:0009988 25 23 0,000 0,13151183 0,16243196 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13151183 0,16234862 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,13151183 0,16226537 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,13151183 0,1621822 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13682192 0,16864423 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13682192 0,16855788 ! vesicle docking GO:0048278 47 24 0,000 0,13682192 0,16847162 ! spinal cord development GO:0021510 47 24 0,000 0,13682192 0,16838544 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13682192 0,16829935 ! digestive system process GO:0022600 39 24 0,000 0,13682192 0,16821336 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13682192 0,16812745 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13682192 0,16804162 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13682192 0,16795589 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13682192 0,16787024 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13682192 0,16778468 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13682192 0,1676992 ! membrane depolarization GO:0051899 39 24 0,000 0,13682192 0,16761382 ! pentose metabolic process GO:0019321 35 24 0,000 0,13682192 0,16752852 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13682192 0,16744331 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13682192 0,16735818 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13682192 0,16727314 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13682192 0,16718819 ! regulation of amine transport GO:0051952 40 24 0,000 0,13682192 0,16710332 ! protein tetramerization GO:0051262 52 24 0,000 0,13682192 0,16701854 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14209972 0,17337318 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14209972 0,17328531 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,14209972 0,17319753 ! phototransduction GO:0007602 33 25 0,000 0,14209972 0,17310983 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14209972 0,17302223 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,14209972 0,17293471 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14209972 0,17284728 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,14209972 0,17275994 ! receptor metabolic process GO:0043112 46 25 0,000 0,14209972 0,17267269 ! chromosome condensation GO:0030261 45 25 0,000 0,14209972 0,17258552 ! response to starvation GO:0042594 42 25 0,000 0,14209972 0,17249845 ! osteoblast differentiation GO:0001649 60 25 0,000 0,14209972 0,17241146 ! neural crest cell development GO:0014032 54 25 0,000 0,14209972 0,17232456 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14209972 0,17223774 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14209972 0,17215102 ! interaction with host GO:0051701 62 25 0,000 0,14209972 0,17206438 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14209972 0,17197783 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14209972 0,17189136 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,14209972 0,17180498 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14209972 0,17171869 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14209972 0,17163249 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,14209972 0,17154637 ! telomere organization GO:0032200 43 25 0,000 0,14209972 0,17146034 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,14209972 0,1713744 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,14209972 0,17128854 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14734542 0,17752282 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14734542 0,17743397 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14734542 0,17734521 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14734542 0,17725654 ! initiation of viral infection GO:0019059 57 26 0,000 0,14734542 0,17716795 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14734542 0,17707946 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14734542 0,17699105 ! tube lumen formation GO:0035148 50 26 0,000 0,14734542 0,17690273 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14734542 0,1768145 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,14734542 0,17672636 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14734542 0,1766383 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14734542 0,17655034 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,14734542 0,17646246 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14734542 0,17637467 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14734542 0,17628696 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14734542 0,17619934 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14734542 0,17611181 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,14734542 0,17602437 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14734542 0,17593701 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14734542 0,17584974 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14734542 0,17576256 ! blastocyst development GO:0001824 49 26 0,000 0,14734542 0,17567546 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14734542 0,17558845 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14734542 0,17550152 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14734542 0,17541468 ! neuron fate commitment GO:0048663 48 27 0,000 0,15255922 0,18153189 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,15255922 0,18144215 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15255922 0,18135251 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15255922 0,18126295 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! fat cell differentiation GO:0045444 50 27 0,000 0,15255922 0,18117348 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15255922 0,1810841 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,15255922 0,18099481 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,15255922 0,18090561 ! autophagy GO:0006914 41 27 0,000 0,15255922 0,18081649 ! male gonad development GO:0008584 44 27 0,000 0,15255922 0,18072746 ! response to toxin GO:0009636 47 27 0,000 0,15255922 0,18063852 ! primary neural tube formation GO:0014020 51 27 0,000 0,15255922 0,18054967 ! base-excision repair GO:0006284 41 27 0,000 0,15255922 0,1804609 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15255922 0,18037223 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15255922 0,18028363 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15255922 0,18019513 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15774131 0,18622453 ! circadian rhythm GO:0007623 50 28 0,000 0,15774131 0,1861332 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15774131 0,18604196 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15774131 0,1859508 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15774131 0,18585974 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15774131 0,18576877 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15774131 0,18567788 ! synaptogenesis GO:0007416 42 28 0,000 0,15774131 0,18558708 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,15774131 0,18549638 ! lipid oxidation GO:0034440 43 28 0,000 0,15774131 0,18540576 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15774131 0,18531523 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15774131 0,18522479 ! translational initiation GO:0006413 65 29 0,000 0,16289188 0,19117945 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,16289188 0,19108624 ! regulation of pH GO:0006885 43 29 0,000 0,16289188 0,19099311 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16289188 0,19090008 ! catechol metabolic process GO:0009712 54 29 0,000 0,16289188 0,19080714 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,16289188 0,19071429 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16289188 0,19062153 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16289188 0,19052886 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16289188 0,19043628 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,16289188 0,19034379 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,16289188 0,19025139 ! cell fate determination GO:0001709 60 29 0,000 0,16289188 0,19015908 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16289188 0,19006686 ! detection of light stimulus GO:0009583 38 29 0,000 0,16289188 0,18997473 ! tissue homeostasis GO:0001894 48 29 0,000 0,16289188 0,18988269 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,16801113 0,19575534 ! zinc ion transport GO:0006829 45 30 0,000 0,16801113 0,19566059 ! membrane docking GO:0022406 61 30 0,000 0,16801113 0,19556593 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16801113 0,19547136 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16801113 0,19537689 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16801113 0,1952825 ! phospholipid transport GO:0015914 51 30 0,000 0,16801113 0,19518821 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16801113 0,195094 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16801113 0,19499989 ! eye morphogenesis GO:0048592 60 30 0,000 0,16801113 0,19490587 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17309924 0,2007117 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,17309924 0,20061501 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17309924 0,20051842 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17309924 0,20042193 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,17309924 0,20032553 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17309924 0,20022921 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,17309924 0,200133 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17309924 0,20003687 ! ovulation cycle process GO:0022602 49 31 0,000 0,17309924 0,19994084 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17309924 0,1998449 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,17309924 0,19974905 ! peptide transport GO:0015833 55 31 0,000 0,17309924 0,19965329 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17309924 0,19955763 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,17309924 0,19946205 ! mesoderm formation GO:0001707 69 31 0,000 0,17309924 0,19936657 ! natural killer cell activation GO:0030101 45 31 0,000 0,17309924 0,19927118 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17309924 0,19917588 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17309924 0,19908067 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17309924 0,19898556 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,17309924 0,19889053 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,17309924 0,19879559 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1781564 0,20450587 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1781564 0,20440834 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1781564 0,20431091 ! cholesterol transport GO:0030301 56 32 0,000 0,1781564 0,20421358 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1781564 0,20411633 ! spliceosome assembly GO:0000245 67 32 0,000 0,1781564 0,20401918 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1781564 0,20392212 ! metanephros development GO:0001656 74 32 0,000 0,1781564 0,20382515 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,1781564 0,20372828 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1781564 0,20363149 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1781564 0,2035348 ! ovulation cycle GO:0042698 51 32 0,000 0,1781564 0,2034382 ! hindbrain development GO:0030902 61 32 0,000 0,1781564 0,2033417 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,1781564 0,20324528 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1781564 0,20314896 ! gene silencing GO:0016458 65 32 0,000 0,1781564 0,20305272 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,1831828 0,20868268 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,1831828 0,20858392 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1831828 0,20848525 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,1831828 0,20838667 ! formation of primary germ layer GO:0001704 72 33 0,000 0,1831828 0,20828819 ! cell fate specification GO:0001708 52 33 0,000 0,1831828 0,2081898 ! sterol transport GO:0015918 57 33 0,000 0,1831828 0,20809151 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1831828 0,2079933 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,1831828 0,20789519 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,1831828 0,20779718 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18817862 0,2133637 ! glial cell differentiation GO:0010001 63 34 0,000 0,18817862 0,2132632 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18817862 0,21316279 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,18817862 0,21306248 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18817862 0,21296226 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,18817862 0,21286214 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,18817862 0,21276211 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18817862 0,21266217 ! mismatch repair GO:0006298 46 34 0,000 0,18817862 0,21256233 ! spermatid development GO:0007286 63 34 0,000 0,18817862 0,21246258 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18817862 0,21236293 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18817862 0,21226337 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,18817862 0,2121639 ! regulation of muscle development GO:0048634 70 35 0,000 0,19314406 0,21766023 ! negative regulation of secretion GO:0051048 63 35 0,000 0,19314406 0,21755833 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,19314406 0,21745653 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,19314406 0,21735482 ! odontogenesis GO:0042476 66 35 0,000 0,19314406 0,2172532 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,19314406 0,21715168 ! female gonad development GO:0008585 58 35 0,000 0,19314406 0,21705026 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,19314406 0,21694893 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,19314406 0,21684769 ! cytokine production GO:0001816 59 35 0,000 0,19314406 0,21674655 ! neural tube formation GO:0001841 67 35 0,000 0,19314406 0,2166455 ! vesicle localization GO:0051648 64 35 0,000 0,19314406 0,21654455 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,19807928 0,22197427 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,19807928 0,22187093 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19807928 0,22176768 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19807928 0,22166454 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,19807928 0,22156148 ! positive regulation of cell development GO:0010720 80 36 0,000 0,19807928 0,22145853 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,19807928 0,22135567 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19807928 0,2212529 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19807928 0,22115023 ! embryonic organ development GO:0048568 57 36 0,000 0,19807928 0,22104766 ! RNA export from nucleus GO:0006405 56 37 0,000 0,20298449 0,22641663 ! meiosis I GO:0007127 65 37 0,000 0,20298449 0,22631171 ! sister chromatid segregation GO:0000819 58 37 0,000 0,20298449 0,22620689 ! organic anion transport GO:0015711 68 37 0,000 0,20298449 0,22610216 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,20298449 0,22599753 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,20298449 0,225893 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,20298449 0,22578857 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,20298449 0,22568423 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,20298449 0,22557999 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,20298449 0,22547584 ! pigment metabolic process GO:0042440 80 37 0,000 0,20298449 0,22537179 ! spermatid differentiation GO:0048515 66 37 0,000 0,20298449 0,22526784 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20785985 0,23057206 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,20785985 0,2304658 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20785985 0,23035965 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20785985 0,23025359 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,20785985 0,23014763 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,20785985 0,23004176 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,20785985 0,229936 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,20785985 0,22983033 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20785985 0,22972475 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,20785985 0,22961928 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20785985 0,2295139 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,20785985 0,22940862 ! mRNA catabolic process GO:0006402 71 39 0,000 0,21270555 0,23464903 ! learning GO:0007612 77 39 0,000 0,21270555 0,2345415 ! organic ether metabolic process GO:0018904 55 39 0,000 0,21270555 0,23443406 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,21270555 0,23432671 ! ion transmembrane transport GO:0034220 66 39 0,000 0,21270555 0,23421947 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,21270555 0,23411233 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,21270555 0,23400528 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,21270555 0,23389833 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21752176 0,23908514 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21752176 0,23897596 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21752176 0,23886689 ! feeding behavior GO:0007631 59 40 0,000 0,21752176 0,23875792 ! negative regulation of binding GO:0051100 72 40 0,000 0,21752176 0,23864905 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,21752176 0,23854027 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21752176 0,2384316 ! maintenance of protein location GO:0045185 91 40 0,000 0,21752176 0,23832302 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,22230868 0,24345684 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,22230868 0,24334608 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,22230868 0,24323541 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,22230868 0,24312485 ! gliogenesis GO:0042063 88 41 0,000 0,22230868 0,24301439 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,22230868 0,24290403 ! T cell differentiation GO:0030217 81 41 0,000 0,22230868 0,24279377 ! female gamete generation GO:0007292 61 41 0,000 0,22230868 0,24268361 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,22230868 0,24257355 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22706646 0,24765272 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22706646 0,24754051 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22706646 0,2474284 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,22706646 0,24731639 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,2317953 0,25235271 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,2317953 0,25223858 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,2317953 0,25212454 ! neural tube development GO:0021915 77 43 0,000 0,2317953 0,25201062 ! striated muscle contraction GO:0006941 77 43 0,000 0,2317953 0,25189679 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23649536 0,25688842 ! male sex differentiation GO:0046661 76 44 0,000 0,23649536 0,25677249 ! biopolymer methylation GO:0043414 84 44 0,000 0,23649536 0,25665667 ! B cell differentiation GO:0030183 107 44 0,000 0,23649536 0,25654096 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23649536 0,25642535 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,23649536 0,25630984 ! maintenance of location in cell GO:0051651 97 44 0,000 0,23649536 0,25619444 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,24116682 0,26113743 ! glycolysis GO:0006096 65 45 0,000 0,24116682 0,26101996 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,24116682 0,2609026 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,24116682 0,26078534 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,24116682 0,26066818 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,24116682 0,26055113 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,24580986 0,26544817 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,24580986 0,26532908 ! endosome transport GO:0016197 108 47 0,000 0,25042463 0,27018909 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,25042463 0,27006798 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,25042463 0,26994699 ! JNK cascade GO:0007254 91 47 0,000 0,25042463 0,2698261 ! methylation GO:0032259 90 47 0,000 0,25042463 0,26970531 ! protein homooligomerization GO:0051260 76 47 0,000 0,25042463 0,26958464 ! mitochondrial transport GO:0006839 82 48 0,000 0,25501133 0,27439949 ! Notch signaling pathway GO:0007219 96 48 0,000 0,25501133 0,27427682 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,25501133 0,27415427 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25501133 0,27403182 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,25501133 0,27390949 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25957011 0,27868169 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25957011 0,27855739 ! regulation of ion transport GO:0043269 77 49 0,000 0,25957011 0,2784332 ! endocrine system development GO:0035270 104 49 0,000 0,25957011 0,27830913 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,25957011 0,27818516 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25957011 0,2780613 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25957011 0,27793755 ! regulation of ossification GO:0030278 117 50 0,000 0,26410114 0,28266341 ! inner ear development GO:0048839 79 50 0,000 0,26410114 0,28253772 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,26410114 0,28241215 ! viral infectious cycle GO:0019058 99 51 0,000 0,2686046 0,28710025 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,2686046 0,28697276 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,2686046 0,28684539 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,2686046 0,28671813 ! excretion GO:0007588 83 51 0,000 0,2686046 0,28659098 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,2686046 0,28646394 ! chromatin remodeling GO:0006338 109 51 0,000 0,2686046 0,28633702 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,2686046 0,28621021 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,2686046 0,28608351 ! vesicle organization GO:0016050 107 51 0,000 0,2686046 0,28595693 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,2686046 0,28583045 ! membrane fusion GO:0006944 110 52 0,000 0,27308064 0,29046508 ! RNA catabolic process GO:0006401 93 53 0,000 0,27752944 0,29506665 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,27752944 0,29493632 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27752944 0,29480611 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,27752944 0,29467601 ! cell maturation GO:0048469 100 53 0,000 0,27752944 0,29454602 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,27752944 0,29441615 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,28195116 0,29897509 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,28195116 0,29884339 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,28195116 0,2987118 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,28195116 0,29858032 ! chloride transport GO:0006821 90 55 0,000 0,28634596 0,30310092 ! glucose catabolic process GO:0006007 82 55 0,000 0,28634596 0,30296763 ! gastrulation GO:0007369 112 55 0,000 0,28634596 0,30283446 ! RNA elongation GO:0006354 79 55 0,000 0,28634596 0,3027014 ! nuclear export GO:0051168 97 55 0,000 0,28634596 0,30256846 ! regulation of actin filament length GO:0030832 105 56 0,000 0,29071401 0,30704913 ! sensory perception of smell GO:0007608 80 56 0,000 0,29071401 0,3069144 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,29071401 0,30677979 ! regulation of DNA replication GO:0006275 101 56 0,000 0,29071401 0,30664529 ! proton transport GO:0015992 94 56 0,000 0,29071401 0,30651092 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,29071401 0,30637666 ! maintenance of location GO:0051235 118 57 0,000 0,29505547 0,31081588 ! hydrogen transport GO:0006818 97 58 0,000 0,2993705 0,31522338 ! regulation of endocytosis GO:0030100 91 58 0,000 0,2993705 0,31508549 ! positive regulation of secretion GO:0051047 95 59 0,000 0,30365926 0,31945964 ! regulation of cellular component size GO:0032535 109 59 0,000 0,30365926 0,31932001 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,30365926 0,31918051 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,30365926 0,31904113 ! establishment of organelle localization GO:0051656 109 59 0,000 0,30365926 0,31890187 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,30792191 0,3232374 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,30792191 0,32309643 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,30792191 0,32295559 ! camera-type eye development GO:0043010 116 60 0,000 0,30792191 0,32281487 ! kidney development GO:0001822 122 60 0,000 0,30792191 0,32267427 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,31215861 0,32697153 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,31215861 0,32682925 ! mesoderm development GO:0007498 119 61 0,000 0,31215861 0,32668709 ! tRNA processing GO:0008033 89 61 0,000 0,31215861 0,32654505 ! viral reproductive process GO:0022415 126 62 0,000 0,31636951 0,33080619 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,31636951 0,33066248 ! gonad development GO:0008406 98 62 0,000 0,31636951 0,3305189 ! regulation of mitosis GO:0007088 105 63 0,000 0,32055477 0,334746 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,32055477 0,33460077 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,32055477 0,33445567 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,32055477 0,33431069 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,32471454 0,33850225 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,32471454 0,33835565 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,32884899 0,34251544 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,32884899 0,34236723 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,32884899 0,34221915 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,33295826 0,34634569 ! extracellular matrix organization GO:0030198 133 66 0,000 0,33295826 0,34619601 ! secondary metabolic process GO:0019748 116 66 0,000 0,33295826 0,34604647 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,33704251 0,35014001 ! chromosome segregation GO:0007059 113 67 0,000 0,33704251 0,3499889 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,33704251 0,34983791 ! hexose catabolic process GO:0019320 104 67 0,000 0,33704251 0,34968705 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,33704251 0,34953632 ! activation of immune response GO:0002253 105 67 0,000 0,33704251 0,34938573 ! amino acid transport GO:0006865 125 68 0,000 0,34110188 0,35344148 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,34110188 0,35328934 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,34110188 0,35313732 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,34110188 0,35298543 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,34513653 0,35700709 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,34513653 0,35685367 ! urogenital system development GO:0001655 137 69 0,000 0,34513653 0,35670039 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,34513653 0,35654723 ! antigen processing and presentation GO:0019882 104 69 0,000 0,34513653 0,35639421 ! appendage morphogenesis GO:0035107 135 70 0,000 0,34914661 0,36038042 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,35313227 0,36433801 ! reproductive structure development GO:0048608 113 71 0,000 0,35313227 0,36418184 ! appendage development GO:0048736 136 71 0,000 0,35313227 0,36402581 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,35313227 0,36386991 ! regulation of immune effector process GO:0002697 137 71 0,000 0,35313227 0,36371414 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,3610309 0,37169035 ! fertilization GO:0009566 90 73 0,000 0,3610309 0,37153138 ! neurotransmitter transport GO:0006836 123 74 0,000 0,36494417 0,3753979 ! meiosis GO:0007126 121 74 0,000 0,36494417 0,37523747 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,36494417 0,37507718 ! eye development GO:0001654 143 74 0,000 0,36494417 0,37491703 ! organelle localization GO:0051640 136 74 0,000 0,36494417 0,37475701 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36883361 0,37858945 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,36883361 0,378428 ! meiotic cell cycle GO:0051321 122 75 0,000 0,36883361 0,37826669 ! rhythmic process GO:0048511 128 75 0,000 0,36883361 0,37810552 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,36883361 0,37794449 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,37269935 0,38174314 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,37269935 0,3815807 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,37269935 0,38141839 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,37654154 0,38518663 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,37654154 0,38502293 ! blood coagulation GO:0007596 146 78 0,000 0,38036033 0,38876251 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,38036033 0,38859743 ! protein oligomerization GO:0051259 139 78 0,000 0,38036033 0,38843249 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,38415585 0,39214212 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,38415585 0,39197582 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,38792825 0,39565722 ! T cell activation GO:0042110 168 81 0,000 0,39167767 0,39931206 ! digestion GO:0007586 112 81 0,000 0,39167767 0,39914293 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,39167767 0,39897395 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,39540424 0,40259949 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,39540424 0,40242919 ! response to drug GO:0042493 143 82 0,000 0,39540424 0,40225903 ! response to nutrient GO:0007584 125 82 0,000 0,39540424 0,40208901 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,39540424 0,40191914 ! regulation of lyase activity GO:0051339 160 83 0,000 0,39910811 0,40551271 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,4027894 0,40908033 ! hemostasis GO:0007599 158 84 0,000 0,4027894 0,40890772 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,4027894 0,40873526 ! response to unfolded protein GO:0006986 131 85 0,000 0,40644827 0,41227426 ! nucleosome assembly GO:0006334 122 85 0,000 0,40644827 0,41210052 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,40644827 0,41192693 ! amine biosynthetic process GO:0009309 138 86 0,000 0,41008484 0,41543753 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,41008484 0,41526268 ! chromatin assembly GO:0031497 124 86 0,000 0,41008484 0,41508798 ! amine transport GO:0015837 155 86 0,000 0,41008484 0,41491343 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,41369925 0,41839445 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,41369925 0,41821866 ! regulation of neurological system process GO:0031644 148 88 0,000 0,41729164 0,42167311 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,41729164 0,42149609 ! cellular defense response GO:0006968 114 89 0,000 0,42086213 0,42492417 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,42441087 0,42832741 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,42441087 0,42814782 ! sex differentiation GO:0007548 145 90 0,000 0,42441087 0,42796838 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,42441087 0,42778908 ! sterol metabolic process GO:0016125 152 91 0,000 0,42793797 0,43116363 ! response to protein stimulus GO:0051789 149 91 0,000 0,42793797 0,43098316 ! nucleosome organization GO:0034728 138 92 0,000 0,43144358 0,43433191 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,43144358 0,43415025 ! vitamin metabolic process GO:0006766 139 92 0,000 0,43144358 0,43396875 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,43492782 0,43729057 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,43839083 0,44058828 ! female pregnancy GO:0007565 164 94 0,000 0,43839083 0,44040431 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,44183273 0,44367677 ! leukocyte differentiation GO:0002521 202 96 0,000 0,44525364 0,44692543 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,44525364 0,44673906 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,44525364 0,44655284 ! positive regulation of immune response GO:0050778 156 96 0,000 0,44525364 0,44636678 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,44865371 0,44958801 ! hormone metabolic process GO:0042445 157 97 0,000 0,44865371 0,44940084 ! response to virus GO:0009615 160 98 0,000 0,45203305 0,45259738 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,45203305 0,45240911 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,45203305 0,452221 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,45539178 0,45539178