pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6884-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! prostate gland development GO:0030850 5 5 1,000 7,191E-05 0,1325224 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 7,191E-05 0,0662612 ! receptor clustering GO:0043113 5 5 1,000 7,191E-05 0,04417413 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 7,191E-05 0,0331306 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,077E-04 0,03969123 ! purine base biosynthetic process GO:0009113 6 6 1,000 1,077E-04 0,03307602 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 2,003E-04 0,05274745 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 2,003E-04 0,04615402 ! glutamine metabolic process GO:0006541 9 9 1,000 2,572E-04 0,05266059 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 2,572E-04 0,04739453 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 2,572E-04 0,04308594 ! purine base metabolic process GO:0006144 9 9 1,000 2,572E-04 0,03949544 ! actin filament organization GO:0007015 50 48 2,000 2,856E-04 0,04048519 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 3,209E-04 0,04224686 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 3,209E-04 0,03943041 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! regulation of B cell differentiation GO:0045577 10 10 1,000 3,209E-04 0,03696601 ! negative regulation of coagulation GO:0050819 11 10 1,000 3,209E-04 0,03479154 ! protein stabilization GO:0050821 10 10 1,000 3,209E-04 0,03285867 ! signal complex assembly GO:0007172 11 11 1,000 3,916E-04 0,03798424 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 3,916E-04 0,03608503 GO:0032388|positive regulation of intracellular transport, ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 3,916E-04 0,03436669 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 3,916E-04 0,03280457 ! positive regulation of endocytosis GO:0045807 12 12 1,000 4,691E-04 0,03759195 ! protein polymerization GO:0051258 65 60 2,000 5,533E-04 0,04248757 ! receptor metabolic process GO:0043112 14 13 1,000 5,535E-04 0,04080542 ! actin filament bundle formation GO:0051017 13 13 1,000 5,535E-04 0,03923598 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 5,535E-04 0,0377828 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 5,535E-04 0,03643341 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleobase metabolic process GO:0009112 13 13 1,000 5,535E-04 0,03517709 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 5,535E-04 0,03400452 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 1,000 5,535E-04 0,0329076 ! regulation of blood coagulation GO:0030193 15 14 1,000 6,447E-04 0,03713122 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 7,427E-04 0,04147705 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 7,427E-04 0,04025714 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 7,427E-04 0,03910693 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 8,474E-04 0,04338064 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of coagulation GO:0050818 17 16 1,000 8,474E-04 0,04220819 ! positive regulation of transport GO:0051050 71 70 2,000 8,697E-04 0,04218236 ! regulation of transmembrane transport GO:0034762 17 17 1,000 9,588E-04 0,04530815 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 1,077E-03 0,0496156 ! negative regulation of DNA binding GO:0043392 19 18 1,000 1,077E-03 0,04840547 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 1,077E-03 0,04725296 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! negative regulation of catabolic process GO:0009895 18 18 1,000 1,077E-03 0,04615405 ! microtubule-based movement GO:0007018 82 78 2,000 1,192E-03 0,04992731 ! regulation of protein stability GO:0031647 19 19 1,000 1,202E-03 0,04921023 ! negative regulation of binding GO:0051100 21 20 1,000 1,333E-03 0,05340139 ! regulation of B cell activation GO:0050864 20 20 1,000 1,333E-03 0,05226519 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 1,471E-03 0,05647027 ! negative regulation of protein transport GO:0051224 21 21 1,000 1,471E-03 0,05531782 ! hormone-mediated signaling GO:0009755 22 22 1,000 1,615E-03 0,05953453 ! maintenance of protein location in cell GO:0032507 23 22 1,000 1,615E-03 0,05836719 ! pigment biosynthetic process GO:0046148 22 22 1,000 1,615E-03 0,05724474 ! epithelial cell differentiation GO:0030855 23 23 1,000 1,766E-03 0,06141251 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 1,766E-03 0,06027524 ! glucose homeostasis GO:0042593 24 24 1,000 1,923E-03 0,0644531 GO:0033500|carbohydrate homeostasis, ! maintenance of protein location GO:0045185 25 24 1,000 1,923E-03 0,06330216 ! endosome transport GO:0016197 25 25 1,000 2,087E-03 0,06748841 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 2,087E-03 0,06632482 ! regulation of endocytosis GO:0030100 25 25 1,000 2,087E-03 0,06520067 ! negative regulation of immune system process GO:0002683 25 25 1,000 2,087E-03 0,06411399 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 2,257E-03 0,06820587 ! pigment metabolic process GO:0042440 26 26 1,000 2,257E-03 0,06710578 ! maintenance of location in cell GO:0051651 27 26 1,000 2,257E-03 0,0660406 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 2,434E-03 0,070094 ! cAMP-mediated signaling GO:0019933 27 27 1,000 2,434E-03 0,06901564 ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 2,434E-03 0,06796994 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 2,806E-03 0,07719269 ! positive regulation of protein transport GO:0051222 29 29 1,000 2,806E-03 0,0760575 ! regulation of intracellular transport GO:0032386 31 31 1,000 3,203E-03 0,08556582 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 3,203E-03 0,08434345 ! negative regulation of cell motion GO:0051271 31 31 1,000 3,203E-03 0,08315551 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 3,411E-03 0,08732357 ! cell maturation GO:0048469 32 32 1,000 3,411E-03 0,08612736 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 3,411E-03 0,08496347 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 3,411E-03 0,08383063 ! maintenance of location GO:0051235 33 32 1,000 3,411E-03 0,08272759 ! regulation of angiogenesis GO:0045765 35 34 1,000 3,846E-03 0,09205055 ! regulation of protein catabolic process GO:0042176 35 34 1,000 3,846E-03 0,09087041 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 3,846E-03 0,08972016 ! coagulation GO:0050817 39 36 1,000 4,305E-03 0,09916925 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 4,543E-03 0,10337176 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 4,543E-03 0,10211113 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 1,000 4,543E-03 0,10088088 ! urogenital system development GO:0001655 38 38 1,000 4,788E-03 0,10504492 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 5,038E-03 0,10924075 ! hemostasis GO:0007599 42 39 1,000 5,038E-03 0,10797051 ! respiratory tube development GO:0030323 40 39 1,000 5,038E-03 0,10672947 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 5,038E-03 0,10551663 ! respiratory system development GO:0060541 40 39 1,000 5,038E-03 0,10433105 ! developmental maturation GO:0021700 39 39 1,000 5,038E-03 0,10317182 ! positive regulation of cell motion GO:0051272 39 39 1,000 5,038E-03 0,10203806 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 5,295E-03 0,10606659 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 5,557E-03 0,11012585 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 5,825E-03 0,11421424 ! protein ubiquitination GO:0016567 43 42 1,000 5,825E-03 0,11301198 ! reproductive structure development GO:0048608 43 43 1,000 6,099E-03 0,11709764 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 6,099E-03 0,11589045 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 6,099E-03 0,11470789 ! regulation of DNA binding GO:0051101 47 45 1,000 6,665E-03 0,12408097 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 6,957E-03 0,12821311 ! tube morphogenesis GO:0035239 47 46 1,000 6,957E-03 0,12694367 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 6,957E-03 0,12569913 ! regulation of catabolic process GO:0009894 48 47 1,000 7,254E-03 0,12979785 ! gland development GO:0048732 51 49 1,000 7,866E-03 0,13938858 ! negative regulation of transport GO:0051051 51 50 1,000 8,18E-03 0,14357776 ! RNA transport GO:0050658 50 50 1,000 8,18E-03 0,14222326 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 8,18E-03 0,14089407 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 8,5E-03 0,14504878 ! RNA localization GO:0006403 52 52 1,000 8,825E-03 0,14922171 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 8,825E-03 0,14786515 ! regulation of body fluid levels GO:0050878 55 52 1,000 8,825E-03 0,14653304 ! response to hypoxia GO:0001666 53 53 1,000 9,156E-03 0,15067237 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 9,156E-03 0,14933898 ! regulation of protein transport GO:0051223 53 53 1,000 9,156E-03 0,14802899 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 9,493E-03 0,1521359 ! hormone metabolic process GO:0042445 55 54 1,000 9,493E-03 0,15082438 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 9,493E-03 0,14953528 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 9,835E-03 0,15361086 ! reproductive developmental process GO:0003006 56 56 1,000 0,01018264 0,15770261 ! regulation of binding GO:0051098 60 57 1,000 0,01053563 0,16180967 ! regulation of protein localization GO:0032880 58 57 1,000 0,01053563 0,1604724 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,01125779 0,17006646 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,01238109 0,18551498 GO:0060429|epithelium development, ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,01238109 0,18401889 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,01315631 0,19397667 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,01355175 0,1982212 ! regulation of hormone levels GO:0010817 66 65 1,000 0,01355175 0,1966604 ! rRNA transcription GO:0009303 5 5 0,000 0,01373606 0,19777774 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01373606 0,19624458 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01373606 0,194735 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01373606 0,19324848 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01373606 0,19178447 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01373606 0,19034248 ! reproductive cellular process GO:0048610 5 5 0,000 0,01373606 0,18892202 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,01373606 0,1875226 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01373606 0,18614375 ! metencephalon development GO:0022037 5 5 0,000 0,01373606 0,18478504 ! water transport GO:0006833 5 5 0,000 0,01373606 0,18344602 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01373606 0,18212626 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01373606 0,18082536 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01373606 0,17954291 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01373606 0,17827852 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01373606 0,17703182 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01373606 0,17580243 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01373606 0,17459 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01373606 0,17339418 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01373606 0,17221463 ! filopodium assembly GO:0046847 7 5 0,000 0,01373606 0,17105102 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01373606 0,16990302 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01373606 0,16877034 ! GTP metabolic process GO:0046039 5 5 0,000 0,01373606 0,16765265 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01373606 0,16654967 ! mRNA stabilization GO:0048255 5 5 0,000 0,01373606 0,16546111 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01373606 0,16438669 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01373606 0,16332613 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01373606 0,16227917 ! social behavior GO:0035176 5 5 0,000 0,01373606 0,16124554 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01373606 0,160225 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01373606 0,1592173 ! memory GO:0007613 5 5 0,000 0,01373606 0,15822219 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01373606 0,15723944 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01373606 0,15626883 ! response to lipid GO:0033993 5 5 0,000 0,01373606 0,15531012 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01373606 0,15436311 ! hippocampus development GO:0021766 6 5 0,000 0,01373606 0,15342758 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01373606 0,15250332 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01373606 0,15159012 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01373606 0,1506878 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01373606 0,14979616 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01373606 0,148915 ! heart looping GO:0001947 5 5 0,000 0,01373606 0,14804415 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01373606 0,14718343 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01373606 0,14633266 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01373606 0,14549167 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01373606 0,14466029 ! pH reduction GO:0045851 5 5 0,000 0,01373606 0,14383835 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01373606 0,14302571 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01373606 0,14222219 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01373606 0,14142766 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01373606 0,14064195 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01373606 0,13986492 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01373606 0,13909643 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01373606 0,13833634 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01373606 0,13758451 ! adrenal gland development GO:0030325 5 5 0,000 0,01373606 0,13684081 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01373606 0,13610511 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01373606 0,13537727 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01373606 0,13465718 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01373606 0,13394471 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01373606 0,13323974 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01373606 0,13254215 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01373606 0,13185182 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01373606 0,13116865 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01373606 0,13049253 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01373606 0,12982334 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01373606 0,12916097 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01373606 0,12850533 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01373606 0,12785631 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01373606 0,12721382 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01373606 0,12657775 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01373606 0,12594801 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01373606 0,12532451 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01373606 0,12470714 ! response to ATP GO:0033198 5 5 0,000 0,01373606 0,12409584 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01373606 0,12349049 ! regulation of appetite GO:0032098 5 5 0,000 0,01373606 0,12289102 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01373606 0,12229734 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01373606 0,12170938 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,01373606 0,12112704 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01373606 0,12055024 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01373606 0,11997891 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01373606 0,11941297 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01373606 0,11885235 ! fear response GO:0042596 5 5 0,000 0,01373606 0,11829696 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01373606 0,11774675 ! retinol metabolic process GO:0042572 5 5 0,000 0,01373606 0,11720162 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01373606 0,11666152 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01373606 0,11612638 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01373606 0,11559612 ! parturition GO:0007567 5 5 0,000 0,01373606 0,11507068 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01373606 0,11455 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01373606 0,11403401 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01373606 0,11352265 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01373606 0,11301585 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,01373606 0,11251356 ! protein heterooligomerization GO:0051291 5 5 0,000 0,01373606 0,11201571 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01373606 0,11152225 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01373606 0,11103312 ! response to UV-B GO:0010224 5 5 0,000 0,01373606 0,11054825 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01373606 0,11006761 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01373606 0,10959113 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01373606 0,10911875 ! interaction with symbiont GO:0051702 5 5 0,000 0,01373606 0,10865043 ! cellular extravasation GO:0045123 5 5 0,000 0,01373606 0,10818611 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01373606 0,10772575 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01373606 0,10726928 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01373606 0,10681667 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01373606 0,10636786 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01373606 0,1059228 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01373606 0,10548146 ! response to amine stimulus GO:0014075 5 5 0,000 0,01373606 0,10504378 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01373606 0,10460971 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01373606 0,10417922 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01373606 0,10375226 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01373606 0,10332878 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01373606 0,10290874 ! neuron recognition GO:0008038 5 5 0,000 0,01373606 0,10249211 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01373606 0,10207883 ! decidualization GO:0046697 5 5 0,000 0,01373606 0,10166888 ! hair follicle maturation GO:0048820 5 5 0,000 0,01373606 0,1012622 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01373606 0,10085877 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01373606 0,10045853 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01373606 0,10006146 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01373606 0,09966752 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01373606 0,09927667 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01373606 0,09888887 ! postreplication repair GO:0006301 5 5 0,000 0,01373606 0,09850409 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01373606 0,09812229 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01373606 0,09774344 ! histone methylation GO:0016571 5 5 0,000 0,01373606 0,0973675 ! DNA methylation GO:0006306 5 5 0,000 0,01373606 0,09699445 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01373606 0,09662424 ! T cell lineage commitment GO:0002360 5 5 0,000 0,01373606 0,09625685 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01373606 0,09589224 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01373606 0,09553038 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01373606 0,09517124 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01373606 0,0948148 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01373606 0,09446101 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01373606 0,09410985 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01373606 0,0937613 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01373606 0,09341531 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01373606 0,09307188 ! sterol catabolic process GO:0016127 5 5 0,000 0,01373606 0,09273095 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01373606 0,09239252 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01373606 0,09205655 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01373606 0,09172301 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01373606 0,09139188 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01373606 0,09106313 ! zymogen activation GO:0031638 5 5 0,000 0,01373606 0,09073674 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01373606 0,09041268 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01373606 0,09009093 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01373606 0,08977146 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,01373606 0,08945424 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,01373606 0,08913926 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01373606 0,08882649 ! nucleosome positioning GO:0016584 5 5 0,000 0,01373606 0,08851591 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01373606 0,08820749 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01373606 0,08790122 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01373606 0,08759706 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01373606 0,087295 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01373606 0,08699502 ! NADPH regeneration GO:0006740 5 5 0,000 0,01373606 0,08669709 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01373606 0,0864012 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01373606 0,08610731 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01373606 0,08581542 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01373606 0,08552551 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01373606 0,08523754 ! sarcomere organization GO:0045214 5 5 0,000 0,01373606 0,08495151 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01373606 0,08466739 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01373606 0,08438517 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01373606 0,08410482 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01373606 0,08382633 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01373606 0,08354967 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01373606 0,08327484 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01373606 0,0830018 ! spleen development GO:0048536 5 5 0,000 0,01373606 0,08273056 ! male genitalia development GO:0030539 5 5 0,000 0,01373606 0,08246108 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01373606 0,08219335 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01373606 0,08192735 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01373606 0,08166307 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01373606 0,08140048 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01373606 0,08113958 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01373606 0,08088035 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01373606 0,08062277 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01373606 0,08036683 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01373606 0,0801125 ! ATP catabolic process GO:0006200 5 5 0,000 0,01373606 0,07985978 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01373606 0,07960865 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01373606 0,07935909 ! blastocyst formation GO:0001825 5 5 0,000 0,01373606 0,07911109 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01373606 0,07886464 ! embryonic gut development GO:0048566 5 5 0,000 0,01373606 0,07861972 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01373606 0,07837632 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01373606 0,07813441 ! activation of innate immune response GO:0002218 5 5 0,000 0,01373606 0,077894 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01373606 0,07765506 ! catecholamine transport GO:0051937 5 5 0,000 0,01373606 0,07741759 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01373606 0,07718156 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01373606 0,07694696 ! muscle adaptation GO:0043500 5 5 0,000 0,01373606 0,07671379 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01373606 0,07648203 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01373606 0,07625166 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01373606 0,07602267 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01373606 0,07579506 ! defense response to fungus GO:0050832 5 5 0,000 0,01373606 0,07556881 ! lysogeny GO:0030069 5 5 0,000 0,01373606 0,0753439 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01373606 0,07512033 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01373606 0,07489808 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01373606 0,07467714 ! response to nicotine GO:0035094 5 5 0,000 0,01373606 0,0744575 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01373606 0,07423915 ! mitochondrion localization GO:0051646 5 5 0,000 0,01373606 0,07402208 ! nucleus localization GO:0051647 5 5 0,000 0,01373606 0,07380627 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01373606 0,07359172 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,01395236 0,07453391 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,01435812 0,07647982 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,014769 0,0784417 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,01518497 0,08041927 ! wound healing GO:0042060 74 70 1,000 0,01560601 0,08241225 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,01603208 0,08442036 ! regulation of cell activation GO:0050865 71 71 1,000 0,01603208 0,08417985 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,01646173 0,08619025 ! axon extension GO:0048675 7 6 0,000 0,01646173 0,08594609 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01646173 0,0857033 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,01646173 0,08546189 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,01646173 0,08522182 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01646173 0,08498311 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01646173 0,08474572 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01646173 0,08450966 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01646173 0,08427491 ! virus-host interaction GO:0019048 6 6 0,000 0,01646173 0,08404147 ! regulation of S phase GO:0033261 6 6 0,000 0,01646173 0,08380931 ! myotube differentiation GO:0014902 6 6 0,000 0,01646173 0,08357843 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01646173 0,08334882 ! bone remodeling GO:0046849 6 6 0,000 0,01646173 0,08312046 ! N-glycan processing GO:0006491 6 6 0,000 0,01646173 0,08289336 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01646173 0,08266749 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01646173 0,08244285 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01646173 0,08221943 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01646173 0,08199721 ! RNA methylation GO:0001510 6 6 0,000 0,01646173 0,0817762 ! cartilage condensation GO:0001502 7 6 0,000 0,01646173 0,08155637 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01646173 0,08133772 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,01646173 0,08112024 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,01646173 0,08090392 ! artery development GO:0060840 6 6 0,000 0,01646173 0,08068875 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01646173 0,08047472 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01646173 0,08026182 ! androgen metabolic process GO:0008209 6 6 0,000 0,01646173 0,08005005 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01646173 0,07983939 ! limbic system development GO:0021761 7 6 0,000 0,01646173 0,07962984 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,01646173 0,07942139 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01646173 0,07921402 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,01646173 0,07900773 ! pathogenesis GO:0009405 6 6 0,000 0,01646173 0,07880252 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01646173 0,07859837 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,01646173 0,07839527 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01646173 0,07819322 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01646173 0,07799221 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,01646173 0,07779223 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01646173 0,07759327 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01646173 0,07739533 ! arginine metabolic process GO:0006525 6 6 0,000 0,01646173 0,07719839 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01646173 0,07700246 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01646173 0,07680752 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01646173 0,07661356 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01646173 0,07642058 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01646173 0,07622857 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01646173 0,07603752 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01646173 0,07584742 ! ER overload response GO:0006983 6 6 0,000 0,01646173 0,07565828 ! V(D)J recombination GO:0033151 6 6 0,000 0,01646173 0,07547007 ! focal adhesion formation GO:0048041 7 6 0,000 0,01646173 0,0752828 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01646173 0,07509646 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,01646173 0,07491104 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01646173 0,07472653 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01646173 0,07454292 ! regulation of heart rate GO:0002027 6 6 0,000 0,01646173 0,07436022 ! lipid digestion GO:0044241 6 6 0,000 0,01646173 0,07417841 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01646173 0,07399749 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01646173 0,07381744 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01646173 0,07363827 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01646173 0,07345997 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,01646173 0,07328253 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01646173 0,07310595 ! ruffle organization GO:0031529 6 6 0,000 0,01646173 0,07293021 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,01646173 0,07275532 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01646173 0,07258127 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01646173 0,07240804 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01646173 0,07223564 ! L-amino acid transport GO:0015807 6 6 0,000 0,01646173 0,07206406 ! bone mineralization GO:0030282 6 6 0,000 0,01646173 0,07189329 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01646173 0,07172333 ! negative regulation of ossification GO:0030279 6 6 0,000 0,01646173 0,07155417 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01646173 0,07138581 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,01646173 0,07121824 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01646173 0,07105145 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,01646173 0,07088544 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01646173 0,07072021 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,01646173 0,07055574 ! regulation of organ growth GO:0046620 6 6 0,000 0,01646173 0,07039204 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01646173 0,0702291 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01646173 0,0700669 ! response to dsRNA GO:0043331 6 6 0,000 0,01646173 0,06990546 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,01646173 0,06974476 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01646173 0,06958479 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,01646173 0,06942556 ! genitalia development GO:0048806 6 6 0,000 0,01646173 0,06926705 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01646173 0,06910927 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01646173 0,0689522 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,01646173 0,06879585 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01646173 0,0686402 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01646173 0,06848526 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,01646173 0,06833101 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01646173 0,06817746 ! erythrocyte development GO:0048821 6 6 0,000 0,01646173 0,06802459 ! renal water homeostasis GO:0003091 6 6 0,000 0,01646173 0,06787241 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01646173 0,06772091 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01646173 0,06757009 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01646173 0,06741993 ! ribosome assembly GO:0042255 6 6 0,000 0,01646173 0,06727044 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01646173 0,06712161 ! diencephalon development GO:0021536 6 6 0,000 0,01646173 0,06697344 ! fucose catabolic process GO:0019317 6 6 0,000 0,01646173 0,06682592 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,01646173 0,06667905 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,01646173 0,06653283 ! regulation of lipid transport GO:0032368 6 6 0,000 0,01646173 0,06638724 ! regulation of cell division GO:0051302 6 6 0,000 0,01646173 0,06624229 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01646173 0,06609797 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01646173 0,06595428 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01646173 0,06581121 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01646173 0,06566876 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01646173 0,06552693 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01646173 0,06538571 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01646173 0,0652451 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01646173 0,06510508 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01646173 0,06496567 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01646173 0,06482686 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01646173 0,06468863 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01646173 0,064551 ! thymus development GO:0048538 6 6 0,000 0,01646173 0,06441395 ! lymph node development GO:0048535 6 6 0,000 0,01646173 0,06427748 ! organic cation transport GO:0015695 6 6 0,000 0,01646173 0,06414158 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01646173 0,06400626 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,01646173 0,06387151 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,01646173 0,06373733 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01646173 0,06360371 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01646173 0,06347065 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01646173 0,06333814 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01646173 0,06320619 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01646173 0,06307478 ! alditol metabolic process GO:0019400 6 6 0,000 0,01646173 0,06294392 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01646173 0,0628136 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01646173 0,06268382 ! maternal placenta development GO:0001893 6 6 0,000 0,01646173 0,06255458 ! regulation of embryonic development GO:0045995 6 6 0,000 0,01646173 0,06242586 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01646173 0,06229768 ! localization within membrane GO:0051668 6 6 0,000 0,01646173 0,06217002 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,01778617 0,06703458 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,01778617 0,06689778 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,018237 0,06845376 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,01915325 0,07174684 ! respiratory burst GO:0045730 7 7 0,000 0,01918027 0,0717023 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,01918027 0,07155715 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,01918027 0,07141259 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,01918027 0,07126862 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,01918027 0,07112522 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,01918027 0,0709824 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,01918027 0,07084015 ! regulation of chemokine production GO:0032642 7 7 0,000 0,01918027 0,07069847 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,01918027 0,07055735 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,01918027 0,0704168 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,01918027 0,07027681 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,01918027 0,07013737 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,01918027 0,06999848 ! gene silencing by RNA GO:0031047 7 7 0,000 0,01918027 0,06986015 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,01918027 0,06972235 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,01918027 0,06958511 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,01918027 0,0694484 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,01918027 0,06931222 ! axis specification GO:0009798 7 7 0,000 0,01918027 0,06917658 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,01918027 0,06904147 ! visual behavior GO:0007632 7 7 0,000 0,01918027 0,06890689 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,01918027 0,06877283 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,01918027 0,06863929 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,01918027 0,06850627 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,01918027 0,06837376 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,01918027 0,06824176 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,01918027 0,06811028 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,01918027 0,0679793 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,01918027 0,06784882 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,01918027 0,06771884 ! digestive system development GO:0055123 7 7 0,000 0,01918027 0,06758936 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,01918027 0,06746037 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,01918027 0,06733187 ! protein targeting to ER GO:0045047 8 7 0,000 0,01918027 0,06720387 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,01918027 0,06707635 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,01918027 0,06694931 ! endoderm development GO:0007492 7 7 0,000 0,01918027 0,06682275 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,01918027 0,06669667 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,01918027 0,06657106 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,01918027 0,06644593 ! response to hexose stimulus GO:0009746 7 7 0,000 0,01918027 0,06632126 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,01918027 0,06619707 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,01918027 0,06607333 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,01918027 0,06595006 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,01918027 0,06582725 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,01918027 0,0657049 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,01918027 0,06558299 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,01918027 0,06546154 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,01918027 0,06534054 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,01918027 0,06521999 ! response to X-ray GO:0010165 7 7 0,000 0,01918027 0,06509988 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,01918027 0,06498021 ! UV protection GO:0009650 7 7 0,000 0,01918027 0,06486098 ! DNA integration GO:0015074 7 7 0,000 0,01918027 0,06474219 ! myofibril assembly GO:0030239 7 7 0,000 0,01918027 0,06462383 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,01918027 0,0645059 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,01918027 0,0643884 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,01918027 0,06427133 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,01918027 0,06415469 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,01918027 0,06403847 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,01918027 0,06392267 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,01918027 0,06380728 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,01918027 0,06369231 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,01918027 0,06357776 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,01918027 0,06346362 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,01918027 0,06334988 ! axon cargo transport GO:0008088 7 7 0,000 0,01918027 0,06323655 ! eating behavior GO:0042755 7 7 0,000 0,01918027 0,06312363 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,01918027 0,06301111 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,01918027 0,06289899 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,01918027 0,06278727 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,01918027 0,06267595 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,01918027 0,06256502 ! cranial nerve development GO:0021545 7 7 0,000 0,01918027 0,06245448 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,01918027 0,06234433 ! induction of an organ GO:0001759 7 7 0,000 0,01918027 0,06223457 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,01918027 0,06212519 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,01918027 0,0620162 ! autonomic nervous system development GO:0048483 7 7 0,000 0,01918027 0,06190759 ! intracellular lipid transport GO:0032365 7 7 0,000 0,01918027 0,06179936 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,01918027 0,06169151 ! platelet activation GO:0030168 8 7 0,000 0,01918027 0,06158403 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,01918027 0,06147693 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,01918027 0,0613702 ! natural killer cell activation GO:0030101 7 7 0,000 0,01918027 0,06126384 ! response to gamma radiation GO:0010332 8 7 0,000 0,01918027 0,06115784 ! NADP metabolic process GO:0006739 7 7 0,000 0,01918027 0,06105222 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,01918027 0,06094696 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,01918027 0,06084205 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,01918027 0,06073752 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,01918027 0,06063333 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,01918027 0,06052951 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,01918027 0,06042604 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,01918027 0,06032292 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,01918027 0,06022016 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,01918027 0,06011774 ! cell-cell recognition GO:0009988 8 7 0,000 0,01918027 0,06001568 ! hormone catabolic process GO:0042447 7 7 0,000 0,01918027 0,05991396 ! dopamine metabolic process GO:0042417 7 7 0,000 0,01918027 0,05981258 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,01918027 0,05971154 ! oxygen transport GO:0015671 7 7 0,000 0,01918027 0,05961085 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,01918027 0,05951049 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,01918027 0,05941048 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,01918027 0,0593108 ! regulation of axon extension GO:0030516 7 7 0,000 0,01918027 0,05921145 ! cell killing GO:0001906 7 7 0,000 0,01918027 0,05911243 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,01918027 0,05901375 ! adult feeding behavior GO:0008343 7 7 0,000 0,01918027 0,05891539 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,01918027 0,05881736 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,01918027 0,05871966 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,01918027 0,05862228 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,01918027 0,05852522 ! response to cold GO:0009409 7 7 0,000 0,01918027 0,05842849 ! regulation of cell motion GO:0051270 79 79 1,000 0,01961861 0,05966519 ! tube development GO:0035295 83 81 1,000 0,02056367 0,06243632 ! lipid catabolic process GO:0016042 82 81 1,000 0,02056367 0,06233363 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,02152767 0,06514859 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02189169 0,0661416 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02189169 0,06603335 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02189169 0,06592545 ! positive regulation of translation GO:0045727 8 8 0,000 0,02189169 0,06581791 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02189169 0,06571071 ! superoxide anion generation GO:0042554 8 8 0,000 0,02189169 0,06560387 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02189169 0,06549737 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02189169 0,06539121 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02189169 0,0652854 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02189169 0,06517993 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02189169 0,0650748 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02189169 0,06497001 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02189169 0,06486556 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02189169 0,06476144 ! zinc ion transport GO:0006829 8 8 0,000 0,02189169 0,06465766 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02189169 0,0645542 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02189169 0,06445108 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02189169 0,06434829 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02189169 0,06424582 ! lipid localization GO:0010876 8 8 0,000 0,02189169 0,06414368 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02189169 0,06404187 ! response to cAMP GO:0051591 8 8 0,000 0,02189169 0,06394038 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02189169 0,0638392 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02189169 0,06373835 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02189169 0,06363782 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02189169 0,0635376 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02189169 0,0634377 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02189169 0,06333811 ! sensory perception of taste GO:0050909 8 8 0,000 0,02189169 0,06323884 ! organelle fusion GO:0048284 8 8 0,000 0,02189169 0,06313987 ! pancreas development GO:0031016 8 8 0,000 0,02189169 0,06304121 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02189169 0,06294287 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02189169 0,06284482 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02189169 0,06274709 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02189169 0,06264965 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02189169 0,06255252 ! sperm motility GO:0030317 8 8 0,000 0,02189169 0,06245569 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02189169 0,06235916 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02189169 0,06226293 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02189169 0,06216699 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02189169 0,06207135 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02189169 0,061976 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02189169 0,06188095 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02189169 0,06178618 ! Golgi organization GO:0007030 8 8 0,000 0,02189169 0,06169171 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02189169 0,06159752 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02189169 0,06150362 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02189169 0,06141001 ! fructose metabolic process GO:0006000 8 8 0,000 0,02189169 0,06131668 ! mannose metabolic process GO:0006013 9 8 0,000 0,02189169 0,06122364 ! NAD metabolic process GO:0019674 8 8 0,000 0,02189169 0,06113087 ! sex determination GO:0007530 8 8 0,000 0,02189169 0,06103839 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02189169 0,06094619 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02189169 0,06085426 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,02189169 0,06076262 ! response to fungus GO:0009620 8 8 0,000 0,02189169 0,06067124 ! stem cell differentiation GO:0048863 8 8 0,000 0,02189169 0,06058015 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02189169 0,06048932 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02189169 0,06039877 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02189169 0,06030849 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02189169 0,06021847 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02189169 0,06012873 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02189169 0,06003925 ! vasoconstriction GO:0042310 8 8 0,000 0,02189169 0,05995004 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02189169 0,05986109 ! muscle cell development GO:0055001 8 8 0,000 0,02189169 0,05977241 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02189169 0,05968399 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02189169 0,05959583 ! sensory perception of pain GO:0019233 8 8 0,000 0,02189169 0,05950793 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02189169 0,05942029 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02189169 0,05933291 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02189169 0,05924578 ! chromatin silencing GO:0006342 8 8 0,000 0,02189169 0,05915891 ! tissue regeneration GO:0042246 8 8 0,000 0,02189169 0,05907229 ! salivary gland development GO:0007431 8 8 0,000 0,02189169 0,05898593 ! T cell homeostasis GO:0043029 8 8 0,000 0,02189169 0,05889982 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02189169 0,05881396 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02189169 0,05872835 ! water homeostasis GO:0030104 8 8 0,000 0,02189169 0,05864299 ! cofactor transport GO:0051181 8 8 0,000 0,02189169 0,05855788 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02189169 0,05847301 ! acid secretion GO:0046717 8 8 0,000 0,02189169 0,05838839 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02189169 0,05830401 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02189169 0,05821988 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02189169 0,05813599 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02189169 0,05805234 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02189169 0,05796893 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02189169 0,05788576 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02189169 0,05780283 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02189169 0,05772014 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,02189169 0,05763768 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02189169 0,05755546 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,02189169 0,05747347 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02189169 0,05739172 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02189169 0,05731019 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02189169 0,0572289 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02189169 0,05714784 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02189169 0,05706701 ! developmental induction GO:0031128 8 8 0,000 0,02189169 0,05698641 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02189169 0,05690603 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02189169 0,05682588 ! actin filament polymerization GO:0030041 9 8 0,000 0,02189169 0,05674596 ! peptide hormone processing GO:0016486 8 8 0,000 0,02189169 0,05666626 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02189169 0,05658678 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02189169 0,05650753 ! regulation of cellular localization GO:0060341 86 85 1,000 0,02251039 0,05802327 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,02251039 0,05794223 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,0230087 0,0591423 ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,0240191 0,06165349 ! lactation GO:0007595 10 9 0,000 0,024596 0,0630465 ! embryonic pattern specification GO:0009880 10 9 0,000 0,024596 0,06295893 ! positive regulation of cell size GO:0045793 9 9 0,000 0,024596 0,06287161 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,024596 0,06278453 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,024596 0,06269769 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,024596 0,06261109 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,024596 0,06252473 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,024596 0,06243861 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,024596 0,06235272 ! viral genome replication GO:0019079 9 9 0,000 0,024596 0,06226708 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,024596 0,06218166 ! copper ion transport GO:0006825 9 9 0,000 0,024596 0,06209648 ! lipid phosphorylation GO:0046834 9 9 0,000 0,024596 0,06201153 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,024596 0,06192682 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,024596 0,06184233 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,024596 0,06175808 ! RNA polyadenylation GO:0043631 9 9 0,000 0,024596 0,06167406 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,024596 0,06159026 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,024596 0,06150669 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,024596 0,06142335 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,024596 0,06134023 ! phospholipid efflux GO:0033700 9 9 0,000 0,024596 0,06125734 ! response to alkaloid GO:0043279 10 9 0,000 0,024596 0,06117467 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,024596 0,06109223 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,024596 0,06101 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,024596 0,060928 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,024596 0,06084622 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,024596 0,06076465 ! response to ethanol GO:0045471 9 9 0,000 0,024596 0,06068331 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,024596 0,06060218 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,024596 0,06052127 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,024596 0,06044057 ! methionine metabolic process GO:0006555 9 9 0,000 0,024596 0,06036009 ! cerebral cortex development GO:0021987 9 9 0,000 0,024596 0,06027983 ! response to osmotic stress GO:0006970 9 9 0,000 0,024596 0,06019978 ! pigmentation during development GO:0048066 9 9 0,000 0,024596 0,06011993 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,024596 0,06004031 ! central nervous system neuron development GO:0021954 10 9 0,000 0,024596 0,05996089 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,024596 0,05988168 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,024596 0,05980268 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,024596 0,05972389 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,024596 0,0596453 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,024596 0,05956693 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,024596 0,05948875 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,024596 0,05941079 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,024596 0,05933302 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,024596 0,05925547 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,024596 0,05917811 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,024596 0,05910095 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,024596 0,059024 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,024596 0,05894724 ! DNA replication initiation GO:0006270 9 9 0,000 0,024596 0,05887069 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,024596 0,05879433 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,024596 0,05871817 ! regulation of cellular pH GO:0030641 9 9 0,000 0,024596 0,05864221 ! histone acetylation GO:0016573 9 9 0,000 0,024596 0,05856645 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,024596 0,05849088 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,024596 0,0584155 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,024596 0,05834032 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,024596 0,05826534 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,024596 0,05819054 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,024596 0,05811594 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,024596 0,05804152 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,024596 0,0579673 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,024596 0,05789327 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,024596 0,05781943 ! collagen catabolic process GO:0030574 9 9 0,000 0,024596 0,05774577 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,024596 0,0576723 ! gas transport GO:0015669 9 9 0,000 0,024596 0,05759902 ! cholesterol efflux GO:0033344 9 9 0,000 0,024596 0,05752593 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,024596 0,05745302 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,024596 0,05738029 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,024596 0,05730775 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,024596 0,05723539 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,024596 0,05716322 ! defense response to virus GO:0051607 9 9 0,000 0,024596 0,05709122 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,024596 0,05701941 ! actin filament-based movement GO:0030048 9 9 0,000 0,024596 0,05694778 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,024596 0,05687632 ! tissue morphogenesis GO:0048729 94 93 1,000 0,02662425 0,06148934 ! regulation of response to stress GO:0080134 97 94 1,000 0,02715864 0,06264502 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,02729323 0,06287679 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,02729323 0,06279829 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,02729323 0,06271999 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,02729323 0,06264188 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,02729323 0,06256397 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,02729323 0,06248625 ! neuron maturation GO:0042551 10 10 0,000 0,02729323 0,06240872 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,02729323 0,06233139 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,02729323 0,06225424 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,02729323 0,06217729 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,02729323 0,06210053 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,02729323 0,06202396 ! hormone secretion GO:0046879 10 10 0,000 0,02729323 0,06194757 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,02729323 0,06187138 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,02729323 0,06179537 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,02729323 0,06171954 ! inositol metabolic process GO:0006020 10 10 0,000 0,02729323 0,06164391 ! cAMP metabolic process GO:0046058 10 10 0,000 0,02729323 0,06156846 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,02729323 0,06149319 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,02729323 0,06141811 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,02729323 0,06134321 ! glial cell development GO:0021782 10 10 0,000 0,02729323 0,06126849 ! phototransduction GO:0007602 11 10 0,000 0,02729323 0,06119395 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,02729323 0,0611196 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,02729323 0,06104542 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,02729323 0,06097143 ! fat cell differentiation GO:0045444 10 10 0,000 0,02729323 0,06089761 ! myoblast differentiation GO:0045445 10 10 0,000 0,02729323 0,06082398 ! centrosome cycle GO:0007098 10 10 0,000 0,02729323 0,06075052 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,02729323 0,06067724 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,02729323 0,06060413 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,02729323 0,0605312 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,02729323 0,06045845 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,02729323 0,06038587 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,02729323 0,06031346 ! protein polyubiquitination GO:0000209 10 10 0,000 0,02729323 0,06024123 ! glutamate metabolic process GO:0006536 11 10 0,000 0,02729323 0,06016917 ! plasma membrane organization GO:0007009 10 10 0,000 0,02729323 0,06009729 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,02729323 0,06002557 ! lysosomal transport GO:0007041 10 10 0,000 0,02729323 0,05995403 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,02729323 0,05988265 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,02729323 0,05981145 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,02729323 0,05974041 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,02729323 0,05966955 ! exocrine system development GO:0035272 10 10 0,000 0,02729323 0,05959885 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,02729323 0,05952832 ! neuromuscular junction development GO:0007528 10 10 0,000 0,02729323 0,05945795 ! embryo implantation GO:0007566 11 10 0,000 0,02729323 0,05938775 ! regulation of protein binding GO:0043393 11 10 0,000 0,02729323 0,05931772 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,02729323 0,05924785 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,02729323 0,05917815 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,02729323 0,05910861 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,02729323 0,05903923 ! protein export from nucleus GO:0006611 10 10 0,000 0,02729323 0,05897002 ! negative regulation of immune response GO:0050777 10 10 0,000 0,02729323 0,05890097 ! cytolysis GO:0019835 10 10 0,000 0,02729323 0,05883208 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,02729323 0,05876335 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,02729323 0,05869478 ! histone deacetylation GO:0016575 10 10 0,000 0,02729323 0,05862637 ! mRNA splice site selection GO:0006376 11 10 0,000 0,02729323 0,05855812 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,02729323 0,05849003 ! gland morphogenesis GO:0022612 10 10 0,000 0,02729323 0,0584221 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,02729323 0,05835433 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,02729323 0,05828671 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,02729323 0,05821925 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,02729323 0,05815194 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,02729323 0,05808479 ! regulation of epidermis development GO:0045682 10 10 0,000 0,02729323 0,05801779 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,02729323 0,05795095 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,02729323 0,05788427 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,02729323 0,05781773 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,02729323 0,05775135 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,02729323 0,05768512 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,02729323 0,05761905 ! nerve development GO:0021675 10 10 0,000 0,02729323 0,05755312 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,02729323 0,05748735 ! gut development GO:0048565 10 10 0,000 0,02729323 0,05742172 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,02729323 0,05735625 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,02729323 0,05729092 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,02729323 0,05722574 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,02729323 0,05716071 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,02729323 0,05709583 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,02933987 0,06130768 ! protein secretion GO:0009306 11 11 0,000 0,0299834 0,06258143 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,0299834 0,06251063 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,0299834 0,06244 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,0299834 0,06236953 ! negative regulation of defense response GO:0031348 11 11 0,000 0,0299834 0,06229921 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,0299834 0,06222906 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,0299834 0,06215906 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,0299834 0,06208921 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,0299834 0,06201953 ! skin development GO:0043588 11 11 0,000 0,0299834 0,06195 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,0299834 0,06188063 ! microtubule-based transport GO:0010970 11 11 0,000 0,0299834 0,06181141 ! endothelial cell migration GO:0043542 11 11 0,000 0,0299834 0,06174235 ! peroxisomal transport GO:0043574 11 11 0,000 0,0299834 0,06167344 ! protein amino acid methylation GO:0006479 11 11 0,000 0,0299834 0,06160468 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,0299834 0,06153608 ! heart contraction GO:0060047 11 11 0,000 0,0299834 0,06146763 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,0299834 0,06139933 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,0299834 0,06133119 ! T cell proliferation GO:0042098 11 11 0,000 0,0299834 0,06126319 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,0299834 0,06119535 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,0299834 0,06112766 ! spinal cord development GO:0021510 11 11 0,000 0,0299834 0,06106011 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,0299834 0,06099272 ! smooth muscle contraction GO:0006939 11 11 0,000 0,0299834 0,06092547 ! cellular response to starvation GO:0009267 11 11 0,000 0,0299834 0,06085837 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,0299834 0,06079142 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,0299834 0,06072462 ! digestive system process GO:0022600 11 11 0,000 0,0299834 0,06065796 ! mitotic spindle organization GO:0007052 11 11 0,000 0,0299834 0,06059145 ! fucose metabolic process GO:0006004 11 11 0,000 0,0299834 0,06052508 ! membrane budding GO:0006900 11 11 0,000 0,0299834 0,06045886 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,0299834 0,06039279 ! monoamine transport GO:0015844 11 11 0,000 0,0299834 0,06032686 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,0299834 0,06026107 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,0299834 0,06019543 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,0299834 0,06012992 ! body fluid secretion GO:0007589 11 11 0,000 0,0299834 0,06006457 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,0299834 0,05999935 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,0299834 0,05993427 ! intermediate filament-based process GO:0045103 11 11 0,000 0,0299834 0,05986934 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,0299834 0,05980455 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,0299834 0,05973989 ! membrane depolarization GO:0051899 11 11 0,000 0,0299834 0,05967538 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,0299834 0,059611 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,0299834 0,05954677 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,0299834 0,05948267 ! oogenesis GO:0048477 11 11 0,000 0,0299834 0,05941871 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,0299834 0,05935489 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,0299834 0,0592912 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,0299834 0,05922765 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,0299834 0,05916424 ! muscle maintenance GO:0046716 12 11 0,000 0,0299834 0,05910096 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,0299834 0,05903782 ! hindbrain development GO:0030902 11 11 0,000 0,0299834 0,05897481 ! steroid catabolic process GO:0006706 11 11 0,000 0,0299834 0,05891194 ! endocrine process GO:0050886 11 11 0,000 0,0299834 0,0588492 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,0299834 0,0587866 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,0299834 0,05872412 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,0299834 0,05866178 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,0299834 0,05859958 ! response to hormone stimulus GO:0009725 102 100 1,000 0,03045633 0,05946082 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,03266651 0,06370834 ! translational initiation GO:0006413 12 12 0,000 0,03266651 0,063641 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,03266651 0,06357379 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,03266651 0,06350673 ! initiation of viral infection GO:0019059 12 12 0,000 0,03266651 0,06343981 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,03266651 0,06337303 ! iron ion transport GO:0006826 13 12 0,000 0,03266651 0,06330639 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,03266651 0,0632399 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,03266651 0,06317354 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,03266651 0,06310732 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,03266651 0,06304124 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,03266651 0,06297529 ! collagen metabolic process GO:0032963 12 12 0,000 0,03266651 0,06290949 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,03266651 0,06284382 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,03266651 0,06277829 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,03266651 0,0627129 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,03266651 0,06264764 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,03266651 0,06258252 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,03266651 0,06251753 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,03266651 0,06245268 ! actomyosin structure organization GO:0031032 12 12 0,000 0,03266651 0,06238796 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,03266651 0,06232338 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,03266651 0,06225893 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,03266651 0,06219461 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,03266651 0,06213042 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,03266651 0,06206637 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,03266651 0,06200245 ! acute-phase response GO:0006953 12 12 0,000 0,03266651 0,06193866 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,03266651 0,06187501 ! vacuolar transport GO:0007034 12 12 0,000 0,03266651 0,06181148 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,03266651 0,06174808 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,03266651 0,06168482 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,03266651 0,06162168 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,03266651 0,06155867 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,03266651 0,06149579 ! male gonad development GO:0008584 12 12 0,000 0,03266651 0,06143304 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,03266651 0,06137042 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,03266651 0,06130792 ! renal system process GO:0003014 12 12 0,000 0,03266651 0,06124556 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,03266651 0,06118331 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,03266651 0,0611212 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,03266651 0,06105921 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,03266651 0,06099735 ! pallium development GO:0021543 13 12 0,000 0,03266651 0,06093561 ! cell fate determination GO:0001709 12 12 0,000 0,03266651 0,060874 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,03266651 0,06081251 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,03266651 0,06075114 ! somitogenesis GO:0001756 13 12 0,000 0,03266651 0,0606899 ! G1 phase GO:0051318 13 12 0,000 0,03266651 0,06062878 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,03266651 0,06056779 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,03266651 0,06050692 ! detection of light stimulus GO:0009583 13 12 0,000 0,03266651 0,06044617 ! synaptogenesis GO:0007416 12 12 0,000 0,03266651 0,06038554 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,03266651 0,06032503 ! hormone transport GO:0009914 12 12 0,000 0,03266651 0,06026465 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,03266651 0,06020438 ! heme biosynthetic process GO:0006783 12 12 0,000 0,03266651 0,06014424 ! spermatid differentiation GO:0048515 13 12 0,000 0,03266651 0,06008421 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,03266651 0,06002431 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,03266651 0,05996452 ! neural tube closure GO:0001843 13 12 0,000 0,03266651 0,05990486 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,03266651 0,05984531 ! negative regulation of translation GO:0017148 12 12 0,000 0,03266651 0,05978588 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,03266651 0,05972657 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,03266651 0,05966738 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,03534259 0,06449149 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,03534259 0,0644277 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,03534259 0,06436403 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,03534259 0,0643005 ! phenol metabolic process GO:0018958 13 13 0,000 0,03534259 0,06423708 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,03534259 0,0641738 ! gluconeogenesis GO:0006094 13 13 0,000 0,03534259 0,06411063 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,03534259 0,06404759 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,03534259 0,06398468 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,03534259 0,06392189 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,03534259 0,06385922 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,03534259 0,06379667 ! regeneration GO:0031099 13 13 0,000 0,03534259 0,06373425 ! keratinization GO:0031424 13 13 0,000 0,03534259 0,06367195 ! post-embryonic development GO:0009791 14 13 0,000 0,03534259 0,06360977 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,03534259 0,06354771 ! patterning of blood vessels GO:0001569 13 13 0,000 0,03534259 0,06348577 ! vasculogenesis GO:0001570 13 13 0,000 0,03534259 0,06342396 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,03534259 0,06336226 ! regulation of innate immune response GO:0045088 13 13 0,000 0,03534259 0,06330068 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,03534259 0,06323923 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,03534259 0,06317789 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,03534259 0,06311667 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,03534259 0,06305557 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,03534259 0,06299459 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,03534259 0,06293372 ! autophagy GO:0006914 13 13 0,000 0,03534259 0,06287297 ! ureteric bud development GO:0001657 13 13 0,000 0,03534259 0,06281235 ! cell aging GO:0007569 13 13 0,000 0,03534259 0,06275183 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,03534259 0,06269144 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,03534259 0,06263116 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,03534259 0,06257099 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,03534259 0,06251094 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,03534259 0,06245101 ! regulation of peptide secretion GO:0002791 13 13 0,000 0,03534259 0,06239119 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,03534259 0,06233149 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,03534259 0,06227189 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,03534259 0,06221242 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,03534259 0,06215306 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,03534259 0,06209381 ! vasodilation GO:0042311 14 13 0,000 0,03534259 0,06203467 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,03534259 0,06197564 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,03534259 0,06191673 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,03534259 0,06185793 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,03534259 0,06179924 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,03534259 0,06174067 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,03534259 0,0616822 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,03534259 0,06162384 ! immunoglobulin production GO:0002377 13 13 0,000 0,03534259 0,0615656 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,03534259 0,06150746 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,03534259 0,06144944 ! cell-cell junction organization GO:0045216 13 13 0,000 0,03534259 0,06139152 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,03534259 0,06133371 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 0,000 0,03534259 0,06127601 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,03534259 0,06121842 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,03534259 0,06116094 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,03534259 0,06110357 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,03534259 0,0610463 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,03534259 0,06098914 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,03534259 0,06093209 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,03534259 0,06087514 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,03534259 0,0608183 ! blastocyst development GO:0001824 13 13 0,000 0,03534259 0,06076157 ! telomere organization GO:0032200 13 13 0,000 0,03534259 0,06070494 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,03534259 0,06064842 ! regulation of amine transport GO:0051952 13 13 0,000 0,03534259 0,060592 ! tissue homeostasis GO:0001894 13 13 0,000 0,03534259 0,06053569 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,03534259 0,06047948 ! protein tetramerization GO:0051262 13 13 0,000 0,03534259 0,06042338 ! neuron fate commitment GO:0048663 14 14 0,000 0,03801166 0,06492632 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,03801166 0,0648662 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,03801166 0,06480619 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,03801166 0,0647463 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,03801166 0,06468651 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,03801166 0,06462684 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,03801166 0,06456728 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,03801166 0,06450782 ! protein amino acid acylation GO:0043543 14 14 0,000 0,03801166 0,06444848 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,03801166 0,06438924 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,03801166 0,06433011 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,03801166 0,0642711 ! vesicle docking GO:0048278 14 14 0,000 0,03801166 0,06421219 ! superoxide metabolic process GO:0006801 15 14 0,000 0,03801166 0,06415338 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,03801166 0,06409469 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,03801166 0,0640361 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,03801166 0,06397762 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,03801166 0,06391925 ! hair cycle GO:0042633 14 14 0,000 0,03801166 0,06386098 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,03801166 0,06380282 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,03801166 0,06374476 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,03801166 0,06368681 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,03801166 0,06362897 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,03801166 0,06357123 ! lysosome organization GO:0007040 14 14 0,000 0,03801166 0,06351359 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,03801166 0,06345606 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,03801166 0,06339864 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,03801166 0,06334132 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,03801166 0,0632841 ! primary neural tube formation GO:0014020 15 14 0,000 0,03801166 0,06322698 ! peptide cross-linking GO:0018149 14 14 0,000 0,03801166 0,06316997 ! regulation of behavior GO:0050795 14 14 0,000 0,03801166 0,06311306 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,03801166 0,06305625 ! base-excision repair GO:0006284 14 14 0,000 0,03801166 0,06299955 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,03801166 0,06294294 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,03801166 0,06288644 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,03801166 0,06283004 ! formation of primary germ layer GO:0001704 14 14 0,000 0,03801166 0,06277374 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,03801166 0,06271754 ! collagen fibril organization GO:0030199 14 14 0,000 0,03801166 0,06266144 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,03801166 0,06260545 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,03801166 0,06254955 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,03801166 0,06249375 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,03801166 0,06243805 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,03801166 0,06238245 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,03801166 0,06232695 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,03801166 0,06227155 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,03801166 0,06221625 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,04067373 0,06651437 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,04067373 0,0664554 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,04067373 0,06639654 ! positive regulation of ossification GO:0045778 15 15 0,000 0,04067373 0,06633778 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,04067373 0,06627913 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,04067373 0,06622058 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,04067373 0,06616213 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,04067373 0,06610378 ! response to vitamin GO:0033273 15 15 0,000 0,04067373 0,06604554 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,04067373 0,0659874 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,04067373 0,06592937 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,04067373 0,06587143 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,04067373 0,0658136 ! ovarian follicle development GO:0001541 15 15 0,000 0,04067373 0,06575587 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,04067373 0,06569824 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,04067373 0,06564071 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,04067373 0,06558328 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,04067373 0,06552595 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,04067373 0,06546873 ! heme metabolic process GO:0042168 15 15 0,000 0,04067373 0,0654116 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,04067373 0,06535457 ! chromosome condensation GO:0030261 15 15 0,000 0,04067373 0,06529764 ! response to starvation GO:0042594 15 15 0,000 0,04067373 0,06524081 ! response to ionizing radiation GO:0010212 16 15 0,000 0,04067373 0,06518408 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,04067373 0,06512745 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,04067373 0,06507091 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,04067373 0,06501448 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,04067373 0,06495814 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,04067373 0,0649019 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,04067373 0,06484575 ! phospholipid transport GO:0015914 15 15 0,000 0,04067373 0,06478971 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,04067373 0,06473376 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,04067373 0,0646779 ! glutathione metabolic process GO:0006749 16 15 0,000 0,04067373 0,06462215 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,04067373 0,06456649 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,04067373 0,06451092 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,04067373 0,06445545 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,04067373 0,06440008 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,04067373 0,0643448 ! protein homooligomerization GO:0051260 15 15 0,000 0,04067373 0,06428961 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,04067373 0,06423453 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,04332882 0,06836903 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,04332882 0,06831054 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,04332882 0,06825216 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,04332882 0,06819387 ! learning GO:0007612 16 16 0,000 0,04332882 0,06813569 ! circadian rhythm GO:0007623 16 16 0,000 0,04332882 0,0680776 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,04332882 0,06801961 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,04332882 0,06796172 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,04332882 0,06790393 ! vacuole organization GO:0007033 16 16 0,000 0,04332882 0,06784624 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,04332882 0,06778864 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,04332882 0,06773115 ! vesicle targeting GO:0006903 17 16 0,000 0,04332882 0,06767375 ! segmentation GO:0035282 17 16 0,000 0,04332882 0,06761645 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,04332882 0,06755924 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,04332882 0,06750213 ! iron ion homeostasis GO:0055072 16 16 0,000 0,04332882 0,06744512 ! positive regulation of cell development GO:0010720 16 16 0,000 0,04332882 0,06738821 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,04332882 0,06733139 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,04332882 0,06727466 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,04332882 0,06721803 ! cell fate specification GO:0001708 16 16 0,000 0,04332882 0,0671615 ! pentose metabolic process GO:0019321 16 16 0,000 0,04332882 0,06710506 ! fatty acid transport GO:0015908 16 16 0,000 0,04332882 0,06704872 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,04332882 0,06699247 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,04332882 0,06693631 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,04332882 0,06688025 ! cofactor catabolic process GO:0051187 16 16 0,000 0,04332882 0,06682429 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,04332882 0,06676841 ! polyol metabolic process GO:0019751 16 16 0,000 0,04332882 0,06671263 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,04332882 0,06665695 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,04332882 0,06660135 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,04332882 0,06654585 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,04332882 0,06649044 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,04332882 0,06643513 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,04332882 0,0663799 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,04332882 0,06632477 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,04332882 0,06626973 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,04597695 0,07026163 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,04597695 0,07020342 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,04597695 0,0701453 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,04597695 0,07008728 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,04597695 0,07002936 ! myelination GO:0042552 17 17 0,000 0,04597695 0,06997153 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,04597695 0,0699138 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,04597695 0,06985616 ! leukocyte adhesion GO:0007159 17 17 0,000 0,04597695 0,06979862 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,04597695 0,06974117 ! sensory perception of smell GO:0007608 17 17 0,000 0,04597695 0,06968382 ! glucose transport GO:0015758 17 17 0,000 0,04597695 0,06962656 ! cell junction assembly GO:0034329 18 17 0,000 0,04597695 0,0695694 ! tissue remodeling GO:0048771 17 17 0,000 0,04597695 0,06951232 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,04597695 0,06945535 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,04597695 0,06939846 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,04597695 0,06934167 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,04597695 0,06928497 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,04597695 0,06922837 ! neural crest cell development GO:0014032 19 17 0,000 0,04597695 0,06917186 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,04597695 0,06911544 ! negative regulation of cell development GO:0010721 18 17 0,000 0,04597695 0,06905911 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,04597695 0,06900287 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,04597695 0,06894672 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,04597695 0,06889067 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,04597695 0,06883471 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,04597695 0,06877883 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,04597695 0,06872305 ! pigmentation GO:0043473 17 17 0,000 0,04597695 0,06866736 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,04597695 0,06861176 ! adult locomotory behavior GO:0008344 17 17 0,000 0,04597695 0,06855625 ! embryonic organ development GO:0048568 17 17 0,000 0,04597695 0,06850083 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,04597695 0,0684455 ! liver development GO:0001889 17 17 0,000 0,04597695 0,06839025 ! gene silencing GO:0016458 17 17 0,000 0,04597695 0,0683351 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,04861814 0,07220244 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,04861814 0,0721443 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,04861814 0,07208626 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,04861814 0,07202832 ! meiosis I GO:0007127 18 18 0,000 0,04861814 0,07197046 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,04861814 0,0719127 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,04861814 0,07185503 ! membrane docking GO:0022406 18 18 0,000 0,04861814 0,07179746 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,04861814 0,07173997 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,04861814 0,07168258 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,04861814 0,07162528 ! hexose transport GO:0008645 18 18 0,000 0,04861814 0,07156807 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,04861814 0,07151095 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,04861814 0,07145393 ! striated muscle contraction GO:0006941 18 18 0,000 0,04861814 0,07139699 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,04861814 0,07134015 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,04861814 0,07128339 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,04861814 0,07122673 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,04861814 0,07117015 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,04861814 0,07111367 ! B cell differentiation GO:0030183 18 18 0,000 0,04861814 0,07105728 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,04861814 0,07100097 ! ensheathment of neurons GO:0007272 18 18 0,000 0,04861814 0,07094475 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,04861814 0,07088863 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,04861814 0,07083259 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,04861814 0,07077664 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,04861814 0,07072078 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,05125239 0,07449381 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,05125239 0,07443511 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,05125239 0,0743765 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,05125239 0,07431798 ! glial cell differentiation GO:0010001 19 19 0,000 0,05125239 0,07425956 ! regulation of pH GO:0006885 19 19 0,000 0,05125239 0,07420122 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,05125239 0,07414298 ! feeding behavior GO:0007631 19 19 0,000 0,05125239 0,07408483 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,05125239 0,07402677 ! peroxisome organization GO:0007031 19 19 0,000 0,05125239 0,0739688 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,05125239 0,07391092 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,05125239 0,07385313 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,05125239 0,07379543 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,05125239 0,07373783 ! metanephros development GO:0001656 19 19 0,000 0,05125239 0,07368031 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,05125239 0,07362288 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,05125239 0,07356554 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,05125239 0,07350829 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,05125239 0,07345113 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,05125239 0,07339406 ! peripheral nervous system development GO:0007422 19 19 0,000 0,05125239 0,07333708 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,05125239 0,07328018 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,05125239 0,07322338 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,05125239 0,07316666 ! eye morphogenesis GO:0048592 19 19 0,000 0,05125239 0,07311003 ! regulation of cell shape GO:0008360 21 19 0,000 0,05125239 0,07305348 ! placenta development GO:0001890 19 19 0,000 0,05125239 0,07299703 ! response to heat GO:0009408 19 19 0,000 0,05125239 0,07294066 ! vesicle localization GO:0051648 20 19 0,000 0,05125239 0,07288438 ! regulation of muscle development GO:0048634 21 20 0,000 0,05387973 0,07656156 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,05387973 0,07650258 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,05387973 0,07644369 ! organic ether metabolic process GO:0018904 20 20 0,000 0,05387973 0,07638488 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,05387973 0,07632617 ! neural tube development GO:0021915 21 20 0,000 0,05387973 0,07626755 ! nucleus organization GO:0006997 20 20 0,000 0,05387973 0,07620902 ! phagocytosis GO:0006909 21 20 0,000 0,05387973 0,07615057 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,05387973 0,07609222 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,05387973 0,07603396 ! protein targeting to membrane GO:0006612 22 20 0,000 0,05387973 0,07597578 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,05387973 0,0759177 ! chromatin remodeling GO:0006338 20 20 0,000 0,05387973 0,0758597 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,05387973 0,07580179 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,05387973 0,07574397 ! lipid oxidation GO:0034440 20 20 0,000 0,05387973 0,07568624 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,05387973 0,0756286 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,05387973 0,07557104 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,05387973 0,07551357 ! RNA modification GO:0009451 20 20 0,000 0,05387973 0,07545619 ! single fertilization GO:0007338 21 20 0,000 0,05387973 0,0753989 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,05650018 0,07900595 ! mRNA catabolic process GO:0006402 21 21 0,000 0,05650018 0,07894605 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,05650018 0,07888624 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,05650018 0,07882652 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,05650018 0,0787669 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,05650018 0,07870736 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,05650018 0,07864791 ! Notch signaling pathway GO:0007219 22 21 0,000 0,05650018 0,07858856 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,05650018 0,07852929 ! ear morphogenesis GO:0042471 21 21 0,000 0,05650018 0,07847011 ! organic anion transport GO:0015711 21 21 0,000 0,05650018 0,07841102 ! cholesterol transport GO:0030301 21 21 0,000 0,05650018 0,07835202 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,05650018 0,07829311 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,05650018 0,07823429 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,05650018 0,07817555 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,05650018 0,07811691 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,05650018 0,07805835 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,05650018 0,07799988 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,05650018 0,0779415 ! regulation of proteolysis GO:0030162 21 21 0,000 0,05650018 0,0778832 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,05650018 0,07782499 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,05650018 0,07776687 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,05650018 0,07770883 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,05911376 0,08124284 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,05911376 0,0811823 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,05911376 0,08112186 ! sister chromatid segregation GO:0000819 22 22 0,000 0,05911376 0,0810615 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,05911376 0,08100123 ! regulation of ion transport GO:0043269 22 22 0,000 0,05911376 0,08094105 ! odontogenesis GO:0042476 22 22 0,000 0,05911376 0,08088096 ! cell junction organization GO:0034330 23 22 0,000 0,05911376 0,08082096 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,05911376 0,08076105 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,05911376 0,08070122 ! ovulation cycle process GO:0022602 22 22 0,000 0,05911376 0,08064149 ! spindle organization GO:0007051 22 22 0,000 0,05911376 0,08058184 ! cell chemotaxis GO:0060326 23 22 0,000 0,05911376 0,08052229 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,05911376 0,08046282 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,05911376 0,08040343 ! male sex differentiation GO:0046661 22 22 0,000 0,05911376 0,08034414 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,05911376 0,08028493 ! biopolymer methylation GO:0043414 22 22 0,000 0,05911376 0,08022581 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,05911376 0,08016678 ! detection of external stimulus GO:0009581 23 22 0,000 0,05911376 0,08010783 ! neuron migration GO:0001764 22 22 0,000 0,05911376 0,08004897 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,05911376 0,0799902 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,05911376 0,07993151 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,05911376 0,07987291 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,05911376 0,0798144 ! aerobic respiration GO:0009060 22 22 0,000 0,05911376 0,07975597 ! cytokine production GO:0001816 22 22 0,000 0,05911376 0,07969762 ! cytokinesis GO:0000910 23 22 0,000 0,05911376 0,07963937 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,05911376 0,07958119 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,06172047 0,0830298 ! viral infectious cycle GO:0019058 23 23 0,000 0,06172047 0,08296924 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,06172047 0,08290876 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,06172047 0,08284838 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,06172047 0,08278808 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,06172047 0,08272787 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,06172047 0,08266775 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,06172047 0,08260772 ! endocrine system development GO:0035270 23 23 0,000 0,06172047 0,08254777 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,06172047 0,08248791 ! positive regulation of growth GO:0045927 23 23 0,000 0,06172047 0,08242813 ! female gonad development GO:0008585 23 23 0,000 0,06172047 0,08236845 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,06172047 0,08230885 ! lipid homeostasis GO:0055088 23 23 0,000 0,06172047 0,08224933 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,06172047 0,0821899 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,06172047 0,08213056 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,06172047 0,0820713 ! cell projection assembly GO:0030031 25 23 0,000 0,06172047 0,08201213 ! mitochondrial transport GO:0006839 24 24 0,000 0,06432034 0,08540518 ! regulation of action potential GO:0001508 24 24 0,000 0,06432034 0,08534369 ! gliogenesis GO:0042063 24 24 0,000 0,06432034 0,08528229 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,06432034 0,08522098 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,06432034 0,08515976 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,06432034 0,08509863 ! T cell differentiation GO:0030217 24 24 0,000 0,06432034 0,08503758 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,06432034 0,08497662 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,06432034 0,08491575 ! ovulation cycle GO:0042698 24 24 0,000 0,06432034 0,08485497 ! fertilization GO:0009566 25 24 0,000 0,06432034 0,08479427 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,06432034 0,08473366 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,06432034 0,08467313 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,06432034 0,0846127 ! glucan metabolic process GO:0044042 25 24 0,000 0,06432034 0,08455234 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,06691338 0,08789834 ! negative regulation of secretion GO:0051048 26 25 0,000 0,06691338 0,08783573 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,06691338 0,08777322 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,06691338 0,08771079 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,06691338 0,08764845 ! cellular component disassembly GO:0022411 26 25 0,000 0,06691338 0,0875862 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,06691338 0,08752404 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,06691338 0,08746196 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,06691338 0,08739998 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,06691338 0,08733808 ! excretion GO:0007588 25 25 0,000 0,06691338 0,08727627 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,06691338 0,08721455 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,06691338 0,08715291 ! gastrulation GO:0007369 25 25 0,000 0,06691338 0,08709136 ! heart morphogenesis GO:0003007 25 25 0,000 0,06691338 0,0870299 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,06691338 0,08696852 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,06691338 0,08690724 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,06691338 0,08684603 ! positive regulation of binding GO:0051099 27 26 0,000 0,06949962 0,0901392 ! positive regulation of defense response GO:0031349 26 26 0,000 0,06949962 0,09007581 ! glycolysis GO:0006096 26 26 0,000 0,06949962 0,09001251 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,06949962 0,0899493 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,06949962 0,08988618 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,06949962 0,08982314 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,06949962 0,0897602 ! cellular defense response GO:0006968 26 26 0,000 0,06949962 0,08969734 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,06949962 0,08963457 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,06949962 0,08957189 ! double-strand break repair GO:0006302 27 26 0,000 0,06949962 0,08950929 ! regulation of protein secretion GO:0050708 26 26 0,000 0,06949962 0,08944679 ! germ cell development GO:0007281 27 26 0,000 0,06949962 0,08938437 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,06949962 0,08932204 GO:0035150|regulation of tube size, ! response to insulin stimulus GO:0032868 28 26 0,000 0,06949962 0,08925979 ! synapse organization GO:0050808 26 26 0,000 0,06949962 0,08919763 ! chloride transport GO:0006821 27 27 0,000 0,07207906 0,09244378 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,07207906 0,0923795 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,07207906 0,0923153 ! learning or memory GO:0007611 28 27 0,000 0,07207906 0,09225119 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,07207906 0,09218717 ! peptide metabolic process GO:0006518 29 27 0,000 0,07207906 0,09212324 ! activation of caspase activity GO:0006919 27 27 0,000 0,07207906 0,0920594 ! mesenchymal cell development GO:0014031 29 27 0,000 0,07207906 0,09199565 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,07207906 0,09193198 ! defense response to bacterium GO:0042742 27 27 0,000 0,07207906 0,09186841 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,07207906 0,09180492 ! cell growth GO:0016049 27 27 0,000 0,07207906 0,09174152 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,07465173 0,09495041 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,07465173 0,09488493 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,07465173 0,09481953 ! carbohydrate transport GO:0008643 28 28 0,000 0,07465173 0,09475423 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,07465173 0,09468902 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,07465173 0,09462389 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,07465173 0,09455886 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,07465173 0,09449392 ! histone modification GO:0016570 28 28 0,000 0,07465173 0,09442906 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,07465173 0,0943643 ! developmental growth GO:0048589 28 28 0,000 0,07465173 0,09429962 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,07465173 0,09423503 ! cartilage development GO:0051216 29 28 0,000 0,07465173 0,09417053 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,07721764 0,09734071 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,07721764 0,09727417 ! viral reproductive process GO:0022415 29 29 0,000 0,07721764 0,09720773 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,07721764 0,09714138 ! leukocyte migration GO:0050900 30 29 0,000 0,07721764 0,09707511 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,07721764 0,09700894 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,07721764 0,09694286 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,07721764 0,09687687 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,07721764 0,09681096 ! tRNA processing GO:0008033 29 29 0,000 0,07721764 0,09674515 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,07721764 0,09667943 ! covalent chromatin modification GO:0016569 29 29 0,000 0,07721764 0,09661379 ! adult behavior GO:0030534 30 29 0,000 0,07721764 0,09654825 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,07721764 0,09648279 ! response to UV GO:0009411 29 29 0,000 0,07721764 0,09641742 ! transition metal ion transport GO:0000041 31 30 0,000 0,07977681 0,09954547 ! RNA catabolic process GO:0006401 30 30 0,000 0,07977681 0,09947812 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,07977681 0,09941086 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,07977681 0,09934369 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,07977681 0,09927661 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,07977681 0,09920962 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,07977681 0,09914273 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,07977681 0,09907592 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,07977681 0,0990092 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,07977681 0,09894257 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,07977681 0,09887603 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,07977681 0,09880959 ! response to temperature stimulus GO:0009266 30 30 0,000 0,07977681 0,09874323 ! regulation of ossification GO:0030278 30 30 0,000 0,07977681 0,09867696 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,07977681 0,09861077 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,07977681 0,09854468 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,07977681 0,09847868 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,07977681 0,09841276 ! vesicle organization GO:0016050 30 30 0,000 0,07977681 0,09834693 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,07977681 0,09828119 ! establishment of organelle localization GO:0051656 31 30 0,000 0,07977681 0,09821554 ! regulation of translational initiation GO:0006446 31 31 0,000 0,08232926 0,10129027 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,08232926 0,10122269 ! membrane fusion GO:0006944 31 31 0,000 0,08232926 0,10115521 ! B cell activation GO:0042113 31 31 0,000 0,08232926 0,10108782 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,08232926 0,10102052 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,08232926 0,10095331 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,08232926 0,10088618 ! ion transmembrane transport GO:0034220 31 31 0,000 0,08232926 0,10081915 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,08232926 0,1007522 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,08232926 0,10068535 ! digestion GO:0007586 31 31 0,000 0,08232926 0,10061858 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,08232926 0,1005519 ! regulation of DNA replication GO:0006275 32 31 0,000 0,08232926 0,10048531 ! regulation of heart contraction GO:0008016 31 31 0,000 0,08232926 0,10041881 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,08232926 0,10035239 ! camera-type eye development GO:0043010 31 31 0,000 0,08232926 0,10028607 ! extracellular matrix organization GO:0030198 31 31 0,000 0,08232926 0,10021983 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,08232926 0,10015368 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,08232926 0,10008761 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,08487499 0,10311444 ! cell redox homeostasis GO:0045454 32 32 0,000 0,08487499 0,10304651 ! muscle fiber development GO:0048747 32 32 0,000 0,08487499 0,10297868 ! glucose catabolic process GO:0006007 32 32 0,000 0,08487499 0,10291093 ! lipid modification GO:0030258 32 32 0,000 0,08487499 0,10284327 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,08487499 0,1027757 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,08487499 0,10270821 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,08487499 0,10264082 ! nuclear export GO:0051168 32 32 0,000 0,08487499 0,10257351 ! kidney development GO:0001822 32 32 0,000 0,08487499 0,1025063 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,08487499 0,10243917 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,08487499 0,10237213 ! negative regulation of cell size GO:0045792 33 33 0,000 0,08741404 0,10536564 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,08741404 0,10529678 ! amino acid transport GO:0006865 33 33 0,000 0,08741404 0,105228 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,08741404 0,10515931 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,08741404 0,10509072 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,08741404 0,10502221 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,08741404 0,10495379 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,08741404 0,10488546 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,08741404 0,10481722 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,08741404 0,10474907 ! regulation of actin filament length GO:0030832 34 34 0,000 0,0899464 0,1077136 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,0899464 0,10764365 ! response to metal ion GO:0010038 34 34 0,000 0,0899464 0,1075738 ! ear development GO:0043583 34 34 0,000 0,0899464 0,10750404 ! muscle cell differentiation GO:0042692 35 34 0,000 0,0899464 0,10743436 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,0899464 0,10736478 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,0899464 0,10729529 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,0899464 0,10722589 ! secondary metabolic process GO:0019748 34 34 0,000 0,0899464 0,10715658 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,0899464 0,10708735 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,0899464 0,10701822 ! viral reproduction GO:0016032 34 34 0,000 0,0899464 0,10694918 ! detection of stimulus GO:0051606 36 34 0,000 0,0899464 0,10688022 ! acute inflammatory response GO:0002526 35 35 0,000 0,09247212 0,10981064 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 0,000 0,09247212 0,10973993 ! regulation of cellular component size GO:0032535 35 35 0,000 0,09247212 0,10966931 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,09247212 0,10959878 ! mesoderm development GO:0007498 35 35 0,000 0,09247212 0,10952835 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,09247212 0,109458 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,09247212 0,10938775 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,09247212 0,10931758 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,09247212 0,10924751 ! inorganic anion transport GO:0015698 35 35 0,000 0,09247212 0,10917752 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,09247212 0,10910762 ! regulation of immune effector process GO:0002697 35 35 0,000 0,09247212 0,10903782 ! hydrogen transport GO:0006818 36 36 0,000 0,09499119 0,11193654 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,09499119 0,11186502 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,09499119 0,11179359 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,09499119 0,11172224 ! regulation of mitosis GO:0007088 37 36 0,000 0,09499119 0,11165099 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 0,000 0,09499119 0,11157983 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,09499119 0,11150876 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,09499119 0,11143778 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,09499119 0,11136689 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,09499119 0,11129609 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,09499119 0,11122538 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,09499119 0,11115476 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,09499119 0,11108424 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,09499119 0,11101379 ! gonad development GO:0008406 36 36 0,000 0,09499119 0,11094344 ! regulation of lipase activity GO:0060191 36 36 0,000 0,09499119 0,11087318 ! activation of immune response GO:0002253 36 36 0,000 0,09499119 0,11080301 ! meiosis GO:0007126 37 37 0,000 0,09750363 0,11366173 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,09750363 0,11358988 ! response to drug GO:0042493 37 37 0,000 0,09750363 0,11351812 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,09750363 0,11344646 ! eye development GO:0001654 37 37 0,000 0,09750363 0,11337488 ! negative regulation of growth GO:0045926 37 37 0,000 0,09750363 0,1133034 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,09750363 0,113232 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,09750363 0,1131607 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,09750363 0,11308948 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,09750363 0,11301836 ! adaptive immune response GO:0002250 37 37 0,000 0,09750363 0,11294732 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,10000946 0,11577729 ! neurotransmitter transport GO:0006836 40 38 0,000 0,10000946 0,11570461 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,10000946 0,11563202 ! exocytosis GO:0006887 40 38 0,000 0,10000946 0,11555953 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,10000946 0,11548712 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,10000946 0,1154148 ! chromosome segregation GO:0007059 38 38 0,000 0,10000946 0,11534258 ! hexose catabolic process GO:0019320 38 38 0,000 0,10000946 0,11527045 ! RNA elongation GO:0006354 38 38 0,000 0,10000946 0,1151984 ! meiotic cell cycle GO:0051321 38 38 0,000 0,10000946 0,11512645 ! axon guidance GO:0007411 39 38 0,000 0,10000946 0,11505458 ! regulation of neurological system process GO:0031644 38 38 0,000 0,10000946 0,11498281 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,10000946 0,11491112 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,10000946 0,11483953 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,10250871 0,11763608 ! activation of MAPK activity GO:0000187 39 39 0,000 0,10250871 0,11756288 ! response to unfolded protein GO:0006986 39 39 0,000 0,10250871 0,11748977 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,10250871 0,11741675 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,10250871 0,11734382 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,10250871 0,11727098 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,10250871 0,11719823 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,10250871 0,11712557 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,10250871 0,117053 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,10250871 0,11698053 ! limb development GO:0060173 39 39 0,000 0,10250871 0,11690814 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,10250871 0,11683584 ! DNA catabolic process GO:0006308 41 40 0,000 0,10500137 0,11960293 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,10500137 0,11952905 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,10500137 0,11945527 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,10500137 0,11938158 ! organelle localization GO:0051640 41 40 0,000 0,10500137 0,11930797 ! cell cycle checkpoint GO:0000075 42 41 0,000 0,10748748 0,12205757 ! amine catabolic process GO:0009310 42 41 0,000 0,10748748 0,12198241 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,10748748 0,12190734 ! regulation of caspase activity GO:0043281 41 41 0,000 0,10748748 0,12183237 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,10748748 0,12175749 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,10748748 0,1216827 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,10748748 0,121608 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,10748748 0,12153339 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,10996705 0,12426074 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,10996705 0,1241846 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,10996705 0,12410855 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,10996705 0,1240326 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,10996705 0,12395674 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,10996705 0,12388097 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,10996705 0,12380529 ! forebrain development GO:0030900 43 42 0,000 0,10996705 0,12372971 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,10996705 0,12365422 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,10996705 0,12357882 ! mitochondrion organization GO:0007005 44 43 0,000 0,11244008 0,12628097 ! alcohol catabolic process GO:0046164 43 43 0,000 0,11244008 0,12620406 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,11244008 0,12612725 ! humoral immune response GO:0006959 44 44 0,000 0,11490661 0,12881562 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,11490661 0,12873731 ! mRNA transport GO:0051028 44 44 0,000 0,11490661 0,1286591 ! protein import into nucleus GO:0006606 44 44 0,000 0,11490661 0,12858098 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,11490661 0,12850296 ! vitamin metabolic process GO:0006766 44 44 0,000 0,11490661 0,12842503 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,11490661 0,1283472 ! amine biosynthetic process GO:0009309 46 45 0,000 0,11736664 0,13101558 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,11736664 0,13093627 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,11736664 0,13085706 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,11736664 0,13077794 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,11736664 0,13069892 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,11736664 0,13062 ! nuclear import GO:0051170 45 45 0,000 0,11736664 0,13054117 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,11736664 0,13046244 ! protein processing GO:0016485 45 45 0,000 0,11736664 0,1303838 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,11982019 0,13302929 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,11982019 0,1329492 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,11982019 0,1328692 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,11982019 0,13278931 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,11982019 0,1327095 ! regulation of membrane potential GO:0042391 46 46 0,000 0,11982019 0,1326298 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,12226728 0,13525726 ! regulation of blood pressure GO:0008217 48 47 0,000 0,12226728 0,13517613 ! sex differentiation GO:0007548 47 47 0,000 0,12226728 0,13509509 ! amine transport GO:0015837 47 47 0,000 0,12226728 0,13501414 ! rhythmic process GO:0048511 47 47 0,000 0,12226728 0,1349333 ! calcium ion transport GO:0006816 48 48 0,000 0,12470793 0,13754441 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,12470793 0,13746215 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,12470793 0,13737998 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,12470793 0,13729792 ! protein localization in nucleus GO:0034504 48 48 0,000 0,12470793 0,13721595 ! DNA recombination GO:0006310 48 48 0,000 0,12470793 0,13713408 ! leukocyte differentiation GO:0002521 50 49 0,000 0,12714214 0,13972747 ! ossification GO:0001503 50 49 0,000 0,12714214 0,1396442 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 0,000 0,12714214 0,13956103 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,12714214 0,13947796 ! divalent metal ion transport GO:0070838 49 49 0,000 0,12714214 0,13939498 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,12714214 0,13931211 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,12714214 0,13922933 ! response to bacterium GO:0009617 50 49 0,000 0,12714214 0,13914665 ! positive regulation of MAP kinase activity GO:0043406 50 49 0,000 0,12714214 0,13906408 ! regulation of ligase activity GO:0051340 50 49 0,000 0,12714214 0,13898159 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,12714214 0,13889921 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,12714214 0,13881692 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,12956994 0,1413839 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,12956994 0,14130024 ! chromatin assembly GO:0031497 50 50 0,000 0,12956994 0,14121668 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,12956994 0,14113322 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,12956994 0,14104985 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,12956994 0,14096659 ! transcription initiation GO:0006352 50 50 0,000 0,12956994 0,14088342 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,12956994 0,14080035 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,12956994 0,14071738 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,13199134 0,14326269 ! positive regulation of immune response GO:0050778 51 51 0,000 0,13199134 0,14317837 ! rRNA metabolic process GO:0016072 51 51 0,000 0,13199134 0,14309414 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,13199134 0,14301002 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,13199134 0,142926 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,13199134 0,14284207 ! protein maturation GO:0051604 51 51 0,000 0,13199134 0,14275824 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,13440636 0,145285 ! cell fate commitment GO:0045165 52 52 0,000 0,13440636 0,14519984 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,13440636 0,14511478 ! response to light stimulus GO:0009416 53 52 0,000 0,13440636 0,14502982 ! sodium ion transport GO:0006814 53 53 0,000 0,13681501 0,14754246 ! tRNA metabolic process GO:0006399 53 53 0,000 0,13681501 0,14745618 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,13681501 0,14737 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,13681501 0,14728392 ! regulation of T cell activation GO:0050863 53 53 0,000 0,13681501 0,14719794 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,13921732 0,14969517 ! response to virus GO:0009615 54 54 0,000 0,13921732 0,14960788 ! sulfur metabolic process GO:0006790 55 54 0,000 0,13921732 0,1495207 ! nucleosome organization GO:0034728 55 55 0,000 0,14161328 0,1520054 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,14161328 0,15191693 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,14161328 0,15182855 ! in utero embryonic development GO:0001701 55 55 0,000 0,14161328 0,15174028 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,14161328 0,15165211 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,14400293 0,1541216 ! extracellular structure organization GO:0043062 56 56 0,000 0,14400293 0,15403215 ! regulation of nervous system development GO:0051960 57 56 0,000 0,14400293 0,15394281 ! ATP metabolic process GO:0046034 57 57 0,000 0,14638628 0,15639995 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,14638628 0,15630933 ! innate immune response GO:0045087 58 58 0,000 0,14876333 0,15875554 ! dephosphorylation GO:0016311 60 59 0,000 0,15113412 0,16119223 ! carboxylic acid transport GO:0046942 59 59 0,000 0,15113412 0,161099 GO:0015849|organic acid transport, ! peptidyl-amino acid modification GO:0018193 61 59 0,000 0,15113412 0,16100588 ! regulation of cell development GO:0060284 60 59 0,000 0,15113412 0,16091287 ! sterol metabolic process GO:0016125 59 59 0,000 0,15113412 0,16081996 ! protein localization in organelle GO:0033365 59 59 0,000 0,15113412 0,16072717 ! immune effector process GO:0002252 59 59 0,000 0,15113412 0,16063447 ! potassium ion transport GO:0006813 60 60 0,000 0,15349865 0,16305361 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,15349865 0,16295968 ! cellular respiration GO:0045333 62 61 0,000 0,15585694 0,16536807 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,15585694 0,16527292 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,15585694 0,16517788 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,15585694 0,16508295 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,15585694 0,16498813 ! lipid transport GO:0006869 62 62 0,000 0,158209 0,16738185 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,158209 0,16728582 ! axonogenesis GO:0007409 66 62 0,000 0,158209 0,1671899 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,158209 0,16709409 ! protein import GO:0017038 62 62 0,000 0,158209 0,16699839 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,158209 0,1669028 ! regulation of secretion GO:0051046 65 63 0,000 0,16055485 0,16928066 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,16055485 0,16918387 ! glucose metabolic process GO:0006006 63 63 0,000 0,16055485 0,1690872 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,16055485 0,16899063 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,16055485 0,16889417 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,16289451 0,17125761 ! angiogenesis GO:0001525 65 64 0,000 0,16289451 0,17115997 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,16289451 0,17106244 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,16289451 0,17096502 ! anion transport GO:0006820 65 65 0,000 0,16522799 0,17331542 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,16755531 0,17565667 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,16755531 0,17555681 ! DNA packaging GO:0006323 66 66 0,000 0,16755531 0,17545707 ! regulation of MAP kinase activity GO:0043405 67 66 0,000 0,16755531 0,17535743 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,16755531 0,17525791 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,16987648 0,177585 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,16987648 0,17748433 ! muscle contraction GO:0006936 67 67 0,000 0,16987648 0,17738377 ! striated muscle tissue development GO:0014706 69 67 0,000 0,16987648 0,17728332 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,16987648 0,17718299 ! response to radiation GO:0009314 70 68 0,000 0,17219152 0,17949602 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,17219152 0,17939455 ! regulation of cell size GO:0008361 68 68 0,000 0,17219152 0,1792932 ! regulation of translation GO:0006417 69 69 0,000 0,17450044 0,18159475 ! sensory perception of sound GO:0007605 71 69 0,000 0,17450044 0,18149227 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,17450044 0,18138991 ! response to nutrient levels GO:0031667 69 69 0,000 0,17450044 0,18128766 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,17450044 0,18118552 ! cell part morphogenesis GO:0032990 75 70 0,000 0,17680325 0,1834732 ! growth GO:0040007 70 70 0,000 0,17680325 0,18336995 ! muscle tissue development GO:0060537 72 70 0,000 0,17680325 0,18326681 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,17680325 0,1831638 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,17909998 0,18543892 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,17909998 0,1853348 ! regulation of cell migration GO:0030334 71 71 0,000 0,17909998 0,18523079 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,17909998 0,1851269 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,17909998 0,18502313 ! secretion by cell GO:0032940 75 72 0,000 0,18139064 0,18728457 ! muscle system process GO:0003012 72 72 0,000 0,18139064 0,18717971 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,18139064 0,18707496 ! sensory organ development GO:0007423 72 72 0,000 0,18139064 0,18697033 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,18139064 0,18686582 ! regulation of cytokine production GO:0001817 72 72 0,000 0,18139064 0,18676143 ! electron transport chain GO:0022900 75 74 0,000 0,18595381 0,1913528 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,18595381 0,19124602 ! response to oxidative stress GO:0006979 76 75 0,000 0,18822634 0,19347527 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,19049287 0,19569585 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,1927534 0,19790781 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,1927534 0,19779761 ! regulation of protein modification process GO:0031399 79 78 0,000 0,19500794 0,1999998 ! metal ion homeostasis GO:0055065 78 78 0,000 0,19500794 0,19988857 ! regulation of immune response GO:0050776 78 78 0,000 0,19500794 0,19977745 ! regulation of locomotion GO:0040012 79 79 0,000 0,19725653 0,20196876 ! nuclear transport GO:0051169 79 79 0,000 0,19725653 0,20185662 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,19949916 0,20403826 ! neuron projection development GO:0031175 85 80 0,000 0,19949916 0,20392509 ! MAPKKK cascade GO:0000165 82 81 0,000 0,20173585 0,2060971 ! lymphocyte activation GO:0046649 82 81 0,000 0,20173585 0,20598292 ! ncRNA processing GO:0034470 83 83 0,000 0,20619149 0,21041579 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,20619149 0,21029934 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,20841046 0,21244495 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,21062356 0,21458221 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,21062356 0,21446365 ! positive regulation of protein kinase activity GO:0045860 89 86 0,000 0,21283079 0,21659147 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,21283079 0,21647193 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,21283079 0,21635253 ! heart development GO:0007507 90 87 0,000 0,21503218 0,21846984 ! male gamete generation GO:0048232 90 88 0,000 0,21722773 0,2205789 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 0,000 0,21722773 0,22045744 GO:0033674|positive regulation of kinase activity, ! chemotaxis GO:0006935 90 89 0,000 0,21941746 0,22255717 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,21941746 0,22243475 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,22160139 0,22452521 ! brain development GO:0007420 91 90 0,000 0,22160139 0,22440185 ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,22377953 0,22648307 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,22377953 0,22635877 ! DNA replication GO:0006260 91 91 0,000 0,22377953 0,2262346 ! visual perception GO:0007601 93 92 0,000 0,2259519 0,22830556 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,2259519 0,22818046 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,2259519 0,2280555 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,2259519 0,22793068 ! blood vessel development GO:0001568 95 94 0,000 0,23027936 0,23216896 ! pattern specification process GO:0007389 96 94 0,000 0,23027936 0,23204202 ! epidermis development GO:0008544 94 94 0,000 0,23027936 0,23191523 ! cofactor metabolic process GO:0051186 95 94 0,000 0,23027936 0,23178857 ! regulation of cell growth GO:0001558 97 96 0,000 0,2345839 0,23599243 ! vasculature development GO:0001944 97 96 0,000 0,2345839 0,23586368 ! endocytosis GO:0006897 99 98 0,000 0,23886562 0,24003781 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,23886562 0,239907 ! blood circulation GO:0008015 99 98 0,000 0,23886562 0,23977633 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,23886562 0,2396458 ! anti-apoptosis GO:0006916 100 99 0,000 0,24099797 0,24165356 ! ectoderm development GO:0007398 99 99 0,000 0,24099797 0,24152216 ! muscle organ development GO:0007517 102 100 0,000 0,24312465 0,24352105 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,24312465 0,24338877 ! response to other organism GO:0051707 101 100 0,000 0,24312465 0,24325664 ! hemopoiesis GO:0030097 104 100 0,000 0,24312465 0,24312465