pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6884-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glutamate signaling pathway GO:0007215 34 22 3,000 3,839E-07 8,829E-04 ! dopamine receptor signaling pathway GO:0007212 22 11 2,000 3,361E-06 3,865E-03 ! actin cytoskeleton reorganization GO:0031532 21 11 2,000 3,361E-06 2,577E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 2,000 9,195E-06 5,287E-03 ! visual learning GO:0008542 35 18 2,000 1,639E-05 7,541E-03 ! regulation of postsynaptic membrane potential GO:0060078 30 19 2,000 1,943E-05 7,448E-03 ! response to ethanol GO:0045471 37 20 2,000 2,281E-05 7,495E-03 ! visual behavior GO:0007632 39 21 2,000 2,656E-05 7,636E-03 ! membrane depolarization GO:0051899 35 22 2,000 3,069E-05 7,844E-03 ! forebrain neuron development GO:0021884 7 5 1,000 7,655E-05 0,0176064 ! early endosome to late endosome transport GO:0045022 11 5 1,000 7,655E-05 0,01600582 ! monocyte differentiation GO:0030224 8 5 1,000 7,655E-05 0,014672 ! regulation of sensory perception GO:0051931 6 5 1,000 7,655E-05 0,01354339 GO:0051930|regulation of sensory perception of pain, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 1,000 7,655E-05 0,012576 ! regulation of membrane potential GO:0042391 128 85 3,000 9,333E-05 0,01431123 ! prostate gland development GO:0030850 9 6 1,000 1,146E-04 0,01647643 ! forebrain neuron differentiation GO:0021879 9 6 1,000 1,146E-04 0,01550723 GO:0021872|generation of neurons in the forebrain, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 1,146E-04 0,01464572 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! purine base biosynthetic process GO:0009113 14 6 1,000 1,146E-04 0,01387489 ! negative regulation of B cell activation GO:0050869 9 6 1,000 1,146E-04 0,01318115 ! learning GO:0007612 67 37 2,000 1,504E-04 0,01646774 ! regulation of pigmentation during development GO:0048070 15 7 1,000 1,602E-04 0,01674595 ! cell maturation GO:0048469 60 45 2,000 2,703E-04 0,02702993 ! receptor clustering GO:0043113 15 9 1,000 2,736E-04 0,02622091 ! epithelial cell development GO:0002064 10 9 1,000 2,736E-04 0,02517207 ! negative regulation of lymphocyte differentiation GO:0045620 11 9 1,000 2,736E-04 0,02420392 ! purine base metabolic process GO:0006144 18 9 1,000 2,736E-04 0,02330747 ! establishment of cell polarity GO:0030010 12 9 1,000 2,736E-04 0,02247506 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 1,000 3,414E-04 0,02707652 GO:0007520|myoblast fusion, ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 3,414E-04 0,02617397 ! nucleobase biosynthetic process GO:0046112 21 10 1,000 3,414E-04 0,02532964 ! regulation of B cell differentiation GO:0045577 16 10 1,000 3,414E-04 0,02453809 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 3,414E-04 0,02379451 ! syncytium formation GO:0006949 15 11 1,000 4,165E-04 0,0281763 ! focal adhesion formation GO:0048041 24 11 1,000 4,165E-04 0,02737127 ! membrane protein proteolysis GO:0033619 18 11 1,000 4,165E-04 0,02661095 GO:0006509|membrane protein ectodomain proteolysis, ! developmental maturation GO:0021700 75 57 2,000 5,444E-04 0,03383837 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 1,000 5,886E-04 0,03562506 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 5,886E-04 0,03471159 ! actin filament organization GO:0007015 95 59 2,000 6,024E-04 0,03463958 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 2,000 6,329E-04 0,03550351 ! neuron maturation GO:0042551 21 14 1,000 6,855E-04 0,03753696 ! myotube differentiation GO:0014902 21 14 1,000 6,855E-04 0,036664 ! startle response GO:0001964 21 14 1,000 6,855E-04 0,03583073 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 1,000 6,855E-04 0,03503449 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! cAMP-mediated signaling GO:0019933 97 63 2,000 7,301E-04 0,03650625 ! embryonic digit morphogenesis GO:0042733 18 15 1,000 7,895E-04 0,038635 ! endothelial cell migration GO:0043542 22 16 1,000 9,007E-04 0,04315709 ! learning or memory GO:0007611 123 68 2,000 9,124E-04 0,042828 ! signal complex assembly GO:0007172 29 17 1,000 1,019E-03 0,04687096 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 1,019E-03 0,04595192 ! cell-substrate junction assembly GO:0007044 39 17 1,000 1,019E-03 0,04506823 ! actin filament bundle formation GO:0051017 26 17 1,000 1,019E-03 0,04421789 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 1,019E-03 0,04339904 ! nucleobase metabolic process GO:0009112 31 17 1,000 1,019E-03 0,04260996 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 1,144E-03 0,04699604 ! protein amino acid ADP-ribosylation GO:0006471 27 18 1,000 1,144E-03 0,04617155 ! glutamine metabolic process GO:0006541 23 18 1,000 1,144E-03 0,04537549 ! pigmentation during development GO:0048066 31 18 1,000 1,144E-03 0,04460641 ! central nervous system neuron development GO:0021954 30 18 1,000 1,144E-03 0,04386297 ! plasma membrane fusion GO:0045026 23 19 1,000 1,277E-03 0,04813348 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 1,277E-03 0,04735713 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 1,000 1,277E-03 0,04660543 ! protein stabilization GO:0050821 26 19 1,000 1,277E-03 0,04587722 ! regulation of adenylate cyclase activity GO:0045761 131 77 2,000 1,308E-03 0,0462992 ! regulation of cyclase activity GO:0031279 132 78 2,000 1,358E-03 0,04732862 ! regulation of cAMP biosynthetic process GO:0030817 136 79 2,000 1,409E-03 0,04836756 ! regulation of lyase activity GO:0051339 133 79 2,000 1,409E-03 0,04765627 ! central nervous system neuron differentiation GO:0021953 33 20 1,000 1,416E-03 0,04719639 ! actin filament-based movement GO:0030048 34 20 1,000 1,416E-03 0,04652215 ! regulation of cAMP metabolic process GO:0030814 141 81 2,000 1,514E-03 0,04905191 ! myeloid leukocyte differentiation GO:0002573 33 21 1,000 1,562E-03 0,04990159 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 2,000 1,624E-03 0,05117551 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 2,000 1,799E-03 0,05590074 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 1,875E-03 0,05750877 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 1,000 1,875E-03 0,05675207 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! negative regulation of catabolic process GO:0009895 34 23 1,000 1,875E-03 0,05601503 ! establishment of RNA localization GO:0051236 128 88 2,000 1,921E-03 0,05664416 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of nucleotide metabolic process GO:0006140 150 89 2,000 1,984E-03 0,05776472 ! receptor metabolic process GO:0043112 37 24 1,000 2,042E-03 0,05871076 ! RNA localization GO:0006403 135 91 2,000 2,114E-03 0,06003215 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 2,000 2,181E-03 0,0611789 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 2,216E-03 0,06139963 ! post-embryonic development GO:0009791 42 26 1,000 2,396E-03 0,06560709 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 2,000 2,462E-03 0,06662593 ! response to light stimulus GO:0009416 153 96 2,000 2,462E-03 0,06585121 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 1,000 2,583E-03 0,06829026 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 2,583E-03 0,06751424 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 2,583E-03 0,06675565 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 2,583E-03 0,06601392 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 2,000 2,765E-03 0,06988056 ! cell junction assembly GO:0034329 56 28 1,000 2,777E-03 0,06942234 ! mesoderm formation GO:0001707 46 28 1,000 2,777E-03 0,06867587 ! regulation of B cell activation GO:0050864 42 28 1,000 2,777E-03 0,06794527 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 2,977E-03 0,07208124 ! formation of primary germ layer GO:0001704 48 29 1,000 2,977E-03 0,0713304 ! spindle organization GO:0007051 37 30 1,000 3,184E-03 0,07550262 ! pigment biosynthetic process GO:0046148 50 30 1,000 3,184E-03 0,07473219 ! adult locomotory behavior GO:0008344 47 30 1,000 3,184E-03 0,07397732 ! negative regulation of cell activation GO:0050866 44 30 1,000 3,184E-03 0,07323754 ! maintenance of protein location in cell GO:0032507 60 31 1,000 3,398E-03 0,07737504 ! mesoderm morphogenesis GO:0048332 49 31 1,000 3,398E-03 0,07661647 ! cell fate specification GO:0001708 37 31 1,000 3,398E-03 0,07587262 ! meiosis I GO:0007127 52 32 1,000 3,618E-03 0,0800097 ! regulation of protein stability GO:0031647 48 32 1,000 3,618E-03 0,0792477 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 3,844E-03 0,08341563 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 63 33 1,000 3,844E-03 0,08263605 ! carbohydrate homeostasis GO:0033500 39 33 1,000 3,844E-03 0,0818709 GO:0042593|glucose homeostasis, ! negative regulation of DNA binding GO:0043392 54 33 1,000 3,844E-03 0,08111979 ! cytokinesis GO:0000910 52 33 1,000 3,844E-03 0,08038234 ! establishment or maintenance of cell polarity GO:0007163 61 34 1,000 4,077E-03 0,08448596 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 4,317E-03 0,08864801 ! maintenance of protein location GO:0045185 65 35 1,000 4,317E-03 0,08786352 ! pigment metabolic process GO:0042440 61 35 1,000 4,317E-03 0,08709278 ! negative regulation of binding GO:0051100 58 36 1,000 4,563E-03 0,09125114 ! hormone-mediated signaling GO:0009755 49 36 1,000 4,563E-03 0,09046449 ! pigmentation GO:0043473 74 38 1,000 5,073E-03 0,09972788 ! maintenance of location in cell GO:0051651 69 38 1,000 5,073E-03 0,09888273 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 5,338E-03 0,10316784 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 1,000 5,338E-03 0,10230811 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 5,609E-03 0,10661258 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 5,609E-03 0,1057387 ! positive regulation of protein transport GO:0051222 55 40 1,000 5,609E-03 0,10487904 ! epithelial cell differentiation GO:0030855 55 41 1,000 5,886E-03 0,1091736 ! endosome transport GO:0016197 71 41 1,000 5,886E-03 0,10830021 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 6,169E-03 0,11261195 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 6,169E-03 0,11172525 ! regulation of cell shape GO:0008360 78 42 1,000 6,169E-03 0,11085239 ! leukocyte migration GO:0050900 60 43 1,000 6,459E-03 0,11515333 ! neuromuscular process GO:0050905 79 43 1,000 6,459E-03 0,11426753 ! activation of adenylate cyclase activity GO:0007190 76 44 1,000 6,754E-03 0,1185837 ! regulation of action potential GO:0001508 71 44 1,000 6,754E-03 0,11768534 ! induction of apoptosis by extracellular signals GO:0008624 74 44 1,000 6,754E-03 0,11680048 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 1,000 7,363E-03 0,12638471 ! positive regulation of cyclase activity GO:0031281 87 47 1,000 7,677E-03 0,13079106 ! negative regulation of immune system process GO:0002683 73 47 1,000 7,677E-03 0,12982936 ! glutamine family amino acid metabolic process GO:0009064 59 47 1,000 7,677E-03 0,1288817 ! gastrulation GO:0007369 73 48 1,000 7,996E-03 0,13327339 ! positive regulation of lyase activity GO:0051349 88 48 1,000 7,996E-03 0,13231458 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 7,996E-03 0,13136948 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 1,000 8,322E-03 0,13574663 ! regulation of intracellular transport GO:0032386 78 49 1,000 8,322E-03 0,13479067 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 8,322E-03 0,13384808 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 8,322E-03 0,13291857 ! maintenance of location GO:0051235 84 49 1,000 8,322E-03 0,1320019 ! skeletal muscle fiber development GO:0048741 73 50 1,000 8,653E-03 0,13631751 ! membrane fusion GO:0006944 80 50 1,000 8,653E-03 0,13539018 ! activation of phospholipase C activity GO:0007202 87 51 1,000 8,99E-03 0,13971551 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 8,99E-03 0,13877782 ! regulation of protein catabolic process GO:0042176 77 51 1,000 8,99E-03 0,13785264 ! adult behavior GO:0030534 80 51 1,000 8,99E-03 0,1369397 ! negative regulation of cell motion GO:0051271 104 51 1,000 8,99E-03 0,13603878 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 9,333E-03 0,14030596 ! establishment of organelle localization GO:0051656 85 52 1,000 9,333E-03 0,13939488 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01003672 0,14893204 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01003672 0,14797734 ! mesoderm development GO:0007498 76 55 1,000 0,01039698 0,15231242 ! lung development GO:0030324 94 59 1,000 0,01189448 0,17314746 ! nucleoside monophosphate metabolic process GO:0009123 95 59 1,000 0,01189448 0,17205848 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,01189448 0,17098312 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,01228281 0,17546869 GO:0035113|embryonic appendage morphogenesis, ! meiosis GO:0007126 96 61 1,000 0,01267666 0,17997721 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,01267666 0,17887305 ! urogenital system development GO:0001655 101 61 1,000 0,01267666 0,17778237 ! respiratory tube development GO:0030323 99 62 1,000 0,01307599 0,18227133 ! meiotic cell cycle GO:0051321 97 62 1,000 0,01307599 0,18117331 ! organelle localization GO:0051640 96 62 1,000 0,01307599 0,18008844 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,01348077 0,18455815 GO:0090046|regulation of transcription regulator activity, ! regulation of lipase activity GO:0060191 109 63 1,000 0,01348077 0,18346609 ! appendage morphogenesis GO:0035107 93 64 1,000 0,01389097 0,18793666 GO:0035108|limb morphogenesis, ! respiratory system development GO:0060541 100 64 1,000 0,01389097 0,18683761 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01393766 0,18637567 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01393766 0,18529835 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01393766 0,18423342 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01393766 0,18318066 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01393766 0,18213986 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01393766 0,18111082 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01393766 0,18009334 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01393766 0,17908724 ! sleep GO:0030431 11 5 0,000 0,01393766 0,17809231 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01393766 0,17710837 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01393766 0,17613525 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01393766 0,17517276 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01393766 0,17422074 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01393766 0,173279 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01393766 0,17234739 ! tongue development GO:0043586 6 5 0,000 0,01393766 0,17142575 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01393766 0,17051391 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01393766 0,16961172 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01393766 0,16871903 ! cobalt ion transport GO:0006824 9 5 0,000 0,01393766 0,16783568 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01393766 0,16696154 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01393766 0,16609645 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01393766 0,16524029 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01393766 0,1643929 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01393766 0,16355416 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01393766 0,16272394 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01393766 0,1619021 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01393766 0,16108852 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01393766 0,16028308 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01393766 0,15948565 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01393766 0,15869612 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01393766 0,15791436 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01393766 0,15714027 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01393766 0,15637373 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01393766 0,15561464 ! malate metabolic process GO:0006108 7 5 0,000 0,01393766 0,15486288 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01393766 0,15411834 ! behavioral response to pain GO:0048266 7 5 0,000 0,01393766 0,15338093 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01393766 0,15265055 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01393766 0,15192709 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01393766 0,15121045 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01393766 0,15050054 ! mating behavior GO:0007617 6 5 0,000 0,01393766 0,14979727 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01393766 0,14910054 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01393766 0,14841026 ! rhythmic behavior GO:0007622 12 5 0,000 0,01393766 0,14772634 ! copulation GO:0007620 7 5 0,000 0,01393766 0,14704869 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01393766 0,14637724 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01393766 0,14571189 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01393766 0,14505256 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01393766 0,14439917 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01393766 0,14375164 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01393766 0,14310989 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01393766 0,14247385 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01393766 0,14184343 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01393766 0,14121857 ! response to protozoan GO:0001562 9 5 0,000 0,01393766 0,14059919 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01393766 0,13998522 ! lymph vessel development GO:0001945 7 5 0,000 0,01393766 0,13937659 ! endochondral ossification GO:0001958 12 5 0,000 0,01393766 0,13877323 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01393766 0,13817507 ! parathyroid gland development GO:0060017 8 5 0,000 0,01393766 0,13758204 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01393766 0,13699408 ! anagen GO:0042640 6 5 0,000 0,01393766 0,13641113 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01393766 0,13583312 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01393766 0,13525998 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01393766 0,13469166 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01393766 0,1341281 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01393766 0,13356923 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01393766 0,133015 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01393766 0,13246535 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01393766 0,13192023 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01393766 0,13137957 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01393766 0,13084333 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01393766 0,13031144 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01393766 0,12978387 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01393766 0,12926055 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01393766 0,12874143 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01393766 0,12822646 ! ovulation GO:0030728 6 5 0,000 0,01393766 0,1277156 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01393766 0,12720879 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01393766 0,12670599 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01393766 0,12620715 ! response to pH GO:0009268 9 5 0,000 0,01393766 0,12571222 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01393766 0,12522115 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01393766 0,12473391 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01393766 0,12425045 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01393766 0,12377072 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01393766 0,12329467 ! polyol catabolic process GO:0046174 7 5 0,000 0,01393766 0,12282228 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01393766 0,12235349 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01393766 0,12188827 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01393766 0,12142657 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01393766 0,12096836 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01393766 0,12051359 ! urea metabolic process GO:0019627 6 5 0,000 0,01393766 0,12006223 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01393766 0,11961424 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01393766 0,11916957 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01393766 0,11872821 ! neutrophil activation GO:0042119 5 5 0,000 0,01393766 0,11829009 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01393766 0,1178552 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01393766 0,1174235 ! response to food GO:0032094 5 5 0,000 0,01393766 0,11699495 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01393766 0,11656951 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01393766 0,11614716 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01393766 0,11572785 ! melanosome organization GO:0032438 7 5 0,000 0,01393766 0,11531157 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01393766 0,11489826 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01393766 0,11448791 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01393766 0,11408048 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01393766 0,11367594 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01393766 0,11327426 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01393766 0,11287541 ! nucleoside transport GO:0015858 6 5 0,000 0,01393766 0,11247935 ! nucleoside salvage GO:0043174 7 5 0,000 0,01393766 0,11208607 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01393766 0,11169552 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01393766 0,11130769 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01393766 0,11092254 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01393766 0,11054005 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01393766 0,11016019 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01393766 0,10978293 ! depyrimidination GO:0045008 8 5 0,000 0,01393766 0,10940824 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01393766 0,10903611 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01393766 0,10866649 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01393766 0,10829938 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01393766 0,10793473 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01393766 0,10757253 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01393766 0,10721276 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01393766 0,10685538 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01393766 0,10650038 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01393766 0,10614773 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01393766 0,10579741 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01393766 0,10544939 ! centrosome duplication GO:0051298 5 5 0,000 0,01393766 0,10510366 ! response to UV-C GO:0010225 6 5 0,000 0,01393766 0,10476018 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01393766 0,10441894 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01393766 0,10407992 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01393766 0,10374309 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01393766 0,10340844 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01393766 0,10307593 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01393766 0,10274556 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01393766 0,1024173 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01393766 0,10209113 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01393766 0,10176703 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01393766 0,10144499 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01393766 0,10112497 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01393766 0,10080697 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01393766 0,10049096 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01393766 0,10017692 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01393766 0,09986485 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01393766 0,09955471 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01393766 0,09924649 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01393766 0,09894017 ! neural tube patterning GO:0021532 6 5 0,000 0,01393766 0,09863574 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01393766 0,09833318 ! histone demethylation GO:0016577 9 5 0,000 0,01393766 0,09803246 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01393766 0,09773358 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01393766 0,09743652 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01393766 0,09714126 ! enteric nervous system development GO:0048484 8 5 0,000 0,01393766 0,09684778 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01393766 0,09655607 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01393766 0,09626611 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01393766 0,09597789 ! transcription termination GO:0006353 8 5 0,000 0,01393766 0,09569139 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01393766 0,09540659 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01393766 0,09512349 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01393766 0,09484206 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01393766 0,09456229 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01393766 0,09428416 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01393766 0,09400767 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01393766 0,09373279 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01393766 0,09345952 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01393766 0,09318784 ! apical protein localization GO:0045176 6 5 0,000 0,01393766 0,09291773 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01393766 0,09264918 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01393766 0,09238218 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01393766 0,09211671 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01393766 0,09185277 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01393766 0,09159033 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01393766 0,09132939 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01393766 0,09106993 ! glial cell migration GO:0008347 10 5 0,000 0,01393766 0,09081194 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01393766 0,09055541 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01393766 0,09030032 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01393766 0,09004667 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01393766 0,08979444 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01393766 0,08954362 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01393766 0,08929419 ! neural plate development GO:0001840 6 5 0,000 0,01393766 0,08904615 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01393766 0,08879949 ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01393766 0,08855419 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01393766 0,08831024 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01393766 0,08806762 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01393766 0,08782634 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01393766 0,08758638 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01393766 0,08734773 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01393766 0,08711037 ! spindle assembly GO:0051225 5 5 0,000 0,01393766 0,0868743 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01393766 0,0866395 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01393766 0,08640597 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01393766 0,0861737 ! organ regeneration GO:0031100 7 5 0,000 0,01393766 0,08594267 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01393766 0,08571288 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01393766 0,08548431 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01393766 0,08525696 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01393766 0,08503081 GO:0055081|anion homeostasis, ! reproductive structure development GO:0048608 90 65 1,000 0,01430656 0,08705049 ! appendage development GO:0048736 94 65 1,000 0,01430656 0,0868208 GO:0060173|limb development, ! cell-substrate adhesion GO:0031589 121 66 1,000 0,0147275 0,08914014 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,01558532 0,09408462 ! regulation of catabolic process GO:0009894 106 70 1,000 0,01646418 0,09912987 ! tRNA transcription GO:0009304 11 6 0,000 0,01670227 0,10030082 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01670227 0,10003962 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01670227 0,09977978 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01670227 0,09952128 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01670227 0,09926412 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01670227 0,09900828 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01670227 0,09875376 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01670227 0,09850055 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01670227 0,09824863 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01670227 0,09799799 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01670227 0,09774864 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01670227 0,09750054 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01670227 0,09725371 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01670227 0,09700812 ! male meiosis GO:0007140 7 6 0,000 0,01670227 0,09676376 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01670227 0,09652064 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01670227 0,09627873 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01670227 0,09603803 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01670227 0,09579854 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01670227 0,09556023 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01670227 0,09532311 ! neuron adhesion GO:0007158 9 6 0,000 0,01670227 0,09508716 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01670227 0,09485238 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01670227 0,09461875 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01670227 0,09438627 ! signal peptide processing GO:0006465 8 6 0,000 0,01670227 0,09415494 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01670227 0,09392473 ! mRNA stabilization GO:0048255 15 6 0,000 0,01670227 0,09369564 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01670227 0,09346767 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01670227 0,09324081 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01670227 0,09301505 ! opsonization GO:0008228 8 6 0,000 0,01670227 0,09279037 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01670227 0,09256678 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01670227 0,09234426 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01670227 0,09212282 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01670227 0,09190243 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01670227 0,09168309 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01670227 0,09146479 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01670227 0,09124754 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01670227 0,09103131 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01670227 0,09081611 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01670227 0,09060192 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01670227 0,09038874 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01670227 0,09017656 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01670227 0,08996537 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01670227 0,08975517 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01670227 0,08954595 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01670227 0,08933771 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01670227 0,08913043 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01670227 0,08892411 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01670227 0,08871874 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01670227 0,08851432 ! thymic T cell selection GO:0045061 12 6 0,000 0,01670227 0,08831084 ! protein lipoylation GO:0009249 10 6 0,000 0,01670227 0,08810829 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01670227 0,08790667 ! pigment granule organization GO:0048753 11 6 0,000 0,01670227 0,08770597 ! drug transport GO:0015893 6 6 0,000 0,01670227 0,08750618 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01670227 0,0873073 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01670227 0,08710933 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01670227 0,08691225 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01670227 0,08671606 ! histidine metabolic process GO:0006547 6 6 0,000 0,01670227 0,08652075 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01670227 0,08632632 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01670227 0,08613277 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,01670227 0,08594008 ! adenohypophysis development GO:0021984 10 6 0,000 0,01670227 0,08574825 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01670227 0,08555727 ! hyperosmotic response GO:0006972 8 6 0,000 0,01670227 0,08536714 ! microtubule nucleation GO:0007020 10 6 0,000 0,01670227 0,08517786 ! ER overload response GO:0006983 7 6 0,000 0,01670227 0,08498941 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01670227 0,0848018 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01670227 0,08461501 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01670227 0,08442904 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01670227 0,08424389 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01670227 0,08405955 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01670227 0,08387601 ! response to dietary excess GO:0002021 7 6 0,000 0,01670227 0,08369328 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01670227 0,08351133 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01670227 0,08333018 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01670227 0,08314981 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01670227 0,08297022 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01670227 0,08279141 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01670227 0,08261336 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01670227 0,08243608 ! neuron apoptosis GO:0051402 8 6 0,000 0,01670227 0,08225956 ! organic alcohol transport GO:0015850 9 6 0,000 0,01670227 0,08208379 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01670227 0,08190877 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01670227 0,0817345 ! male sex determination GO:0030238 9 6 0,000 0,01670227 0,08156096 ! carnitine transport GO:0015879 8 6 0,000 0,01670227 0,08138816 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01670227 0,0812161 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01670227 0,08104475 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01670227 0,08087413 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01670227 0,08070423 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01670227 0,08053504 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01670227 0,08036656 ! parturition GO:0007567 12 6 0,000 0,01670227 0,08019878 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01670227 0,0800317 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01670227 0,07986531 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01670227 0,07969961 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01670227 0,0795346 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01670227 0,07937028 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01670227 0,07920663 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01670227 0,07904365 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01670227 0,07888134 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01670227 0,0787197 ! macrophage differentiation GO:0030225 10 6 0,000 0,01670227 0,07855872 ! astrocyte development GO:0014002 14 6 0,000 0,01670227 0,0783984 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01670227 0,07823872 ! interaction with symbiont GO:0051702 8 6 0,000 0,01670227 0,0780797 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01670227 0,07792133 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01670227 0,07776359 ! eating behavior GO:0042755 6 6 0,000 0,01670227 0,07760649 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01670227 0,07745003 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01670227 0,07729419 ! response to copper ion GO:0046688 9 6 0,000 0,01670227 0,07713898 ! DNA topological change GO:0006265 8 6 0,000 0,01670227 0,0769844 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01670227 0,07683043 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01670227 0,07667707 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01670227 0,07652433 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01670227 0,07637219 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01670227 0,07622066 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01670227 0,07606973 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01670227 0,07591939 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01670227 0,07576965 ! gas homeostasis GO:0033483 11 6 0,000 0,01670227 0,0756205 ! hair follicle maturation GO:0048820 7 6 0,000 0,01670227 0,07547193 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01670227 0,07532395 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01670227 0,07517654 ! Schwann cell development GO:0014044 14 6 0,000 0,01670227 0,07502971 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01670227 0,07488346 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01670227 0,07473777 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01670227 0,07459265 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01670227 0,07444809 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01670227 0,07430409 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01670227 0,07416064 ! histone ubiquitination GO:0016574 7 6 0,000 0,01670227 0,07401775 ! regulation of meiosis GO:0040020 10 6 0,000 0,01670227 0,07387541 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01670227 0,07373362 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01670227 0,07359236 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01670227 0,07345165 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01670227 0,07331148 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01670227 0,07317184 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01670227 0,07303273 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01670227 0,07289414 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01670227 0,07275609 ! receptor internalization GO:0031623 9 6 0,000 0,01670227 0,07261855 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01670227 0,07248154 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01670227 0,07234504 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01670227 0,07220905 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01670227 0,07207357 ! protein deubiquitination GO:0016579 8 6 0,000 0,01670227 0,0719386 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01670227 0,07180414 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01670227 0,07167018 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01670227 0,07153671 ! axonal fasciculation GO:0007413 9 6 0,000 0,01670227 0,07140374 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01670227 0,07127127 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01670227 0,07113928 ! midbrain development GO:0030901 6 6 0,000 0,01670227 0,07100779 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01670227 0,07087678 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01670227 0,07074625 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01670227 0,0706162 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01670227 0,07048663 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01670227 0,07035753 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01670227 0,07022891 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01670227 0,07010076 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01670227 0,06997307 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01670227 0,06984584 ! adult feeding behavior GO:0008343 6 6 0,000 0,01670227 0,06971908 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01670227 0,06959278 ! blastocyst growth GO:0001832 15 6 0,000 0,01670227 0,06946693 ! pigment granule transport GO:0051904 12 6 0,000 0,01670227 0,06934154 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01670227 0,0692166 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01670227 0,06909211 ! catecholamine transport GO:0051937 7 6 0,000 0,01670227 0,06896807 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01670227 0,06884447 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01670227 0,06872131 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01670227 0,0685986 ! protein prenylation GO:0018342 10 6 0,000 0,01670227 0,06847632 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01670227 0,06835447 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01670227 0,06823306 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01670227 0,06811208 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01670227 0,06799153 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01670227 0,0678714 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,01691142 0,0686001 ! muscle cell differentiation GO:0042692 104 71 1,000 0,01691142 0,06847933 ! negative regulation of transport GO:0051051 116 73 1,000 0,01782136 0,07203711 ! tube morphogenesis GO:0035239 118 73 1,000 0,01782136 0,07191073 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,01828399 0,07364831 ! blood coagulation GO:0007596 116 75 1,000 0,0187517 0,07540021 GO:0050817|coagulation, ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,01922445 0,07716622 ! regulation of protein transport GO:0051223 114 76 1,000 0,01922445 0,07703178 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,01945928 0,07783713 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01945928 0,07770199 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01945928 0,07756733 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01945928 0,07743313 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01945928 0,07729939 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01945928 0,07716612 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01945928 0,0770333 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01945928 0,07690094 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01945928 0,07676904 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01945928 0,07663758 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01945928 0,07650658 ! reproductive behavior GO:0019098 12 7 0,000 0,01945928 0,07637602 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01945928 0,07624591 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,01945928 0,07611624 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01945928 0,07598701 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01945928 0,07585822 ! oligopeptide transport GO:0006857 11 7 0,000 0,01945928 0,07572986 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01945928 0,07560194 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01945928 0,07547445 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01945928 0,07534739 ! RNA methylation GO:0001510 11 7 0,000 0,01945928 0,07522075 ! pericardium development GO:0060039 8 7 0,000 0,01945928 0,07509454 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01945928 0,07496876 ! fibril organization GO:0043206 13 7 0,000 0,01945928 0,07484339 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01945928 0,07471844 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01945928 0,07459391 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01945928 0,0744698 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01945928 0,07434609 ! lipoprotein transport GO:0042953 9 7 0,000 0,01945928 0,0742228 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01945928 0,07409991 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01945928 0,07397743 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01945928 0,07385536 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01945928 0,07373369 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01945928 0,07361241 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01945928 0,07349154 ! chemosensory behavior GO:0007635 9 7 0,000 0,01945928 0,07337106 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01945928 0,07325098 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01945928 0,07313129 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01945928 0,07301199 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01945928 0,07289307 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01945928 0,07277455 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01945928 0,07265641 ! reflex GO:0060004 12 7 0,000 0,01945928 0,07253865 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01945928 0,07242127 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01945928 0,07230428 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01945928 0,07218766 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01945928 0,07207141 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01945928 0,07195554 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01945928 0,07184004 ! spinal cord patterning GO:0021511 7 7 0,000 0,01945928 0,07172492 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01945928 0,07161016 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01945928 0,07149576 ! adrenal gland development GO:0030325 17 7 0,000 0,01945928 0,07138173 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01945928 0,07126807 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01945928 0,07115477 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01945928 0,07104182 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01945928 0,07092924 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01945928 0,07081701 ! endosome organization GO:0007032 10 7 0,000 0,01945928 0,07070513 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01945928 0,07059361 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01945928 0,07048244 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01945928 0,07037162 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01945928 0,07026114 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01945928 0,07015102 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01945928 0,07004123 ! galactose metabolic process GO:0006012 10 7 0,000 0,01945928 0,06993179 ! vesicle fusion GO:0006906 15 7 0,000 0,01945928 0,0698227 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01945928 0,06971394 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01945928 0,06960552 ! organ growth GO:0035265 11 7 0,000 0,01945928 0,06949743 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01945928 0,06938969 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01945928 0,06928227 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01945928 0,06917519 ! retinol metabolic process GO:0042572 9 7 0,000 0,01945928 0,06906844 ! behavioral fear response GO:0001662 13 7 0,000 0,01945928 0,06896201 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01945928 0,06885592 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01945928 0,06875015 ! rRNA modification GO:0000154 12 7 0,000 0,01945928 0,06864471 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01945928 0,06853958 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01945928 0,06843478 ! response to UV-B GO:0010224 11 7 0,000 0,01945928 0,0683303 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01945928 0,06822614 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01945928 0,06812229 ! intermediate filament organization GO:0045109 11 7 0,000 0,01945928 0,06801877 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01945928 0,06791555 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01945928 0,06781265 ! fibrinolysis GO:0042730 9 7 0,000 0,01945928 0,06771006 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01945928 0,06760778 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01945928 0,0675058 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01945928 0,06740414 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01945928 0,06730278 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01945928 0,06720172 ! response to tropane GO:0014073 13 7 0,000 0,01945928 0,06710097 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01945928 0,06700052 ! melanosome localization GO:0032400 10 7 0,000 0,01945928 0,06690037 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01945928 0,06680052 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01945928 0,06670097 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01945928 0,06660171 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01945928 0,06650275 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01945928 0,06640408 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01945928 0,0663057 ! mast cell activation GO:0045576 9 7 0,000 0,01945928 0,06620761 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01945928 0,06610982 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01945928 0,06601231 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01945928 0,06591509 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01945928 0,06581816 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01945928 0,06572151 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01945928 0,06562514 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01945928 0,06552906 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01945928 0,06543326 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01945928 0,06533773 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01945928 0,06524249 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01945928 0,06514752 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01945928 0,06505283 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01945928 0,06495841 ! response to tumor cell GO:0002347 12 7 0,000 0,01945928 0,06486427 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01945928 0,0647704 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01945928 0,0646768 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01945928 0,06458347 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01945928 0,06449041 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01945928 0,06439762 ! diuresis GO:0030146 12 7 0,000 0,01945928 0,0643051 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01945928 0,06421284 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01945928 0,06412084 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01945928 0,06402911 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01945928 0,06393764 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01945928 0,06384643 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01945928 0,06375548 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01945928 0,06366479 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01945928 0,06357436 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01945928 0,06348418 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01945928 0,06339426 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01945928 0,06330459 ! lymph node development GO:0048535 9 7 0,000 0,01945928 0,06321518 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01945928 0,06312602 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01945928 0,06303711 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01945928 0,06294845 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01945928 0,06286004 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01945928 0,06277188 ! ATP catabolic process GO:0006200 10 7 0,000 0,01945928 0,06268396 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01945928 0,06259629 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01945928 0,06250887 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01945928 0,06242168 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01945928 0,06233475 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01945928 0,06224805 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01945928 0,06216159 ! muscle adaptation GO:0043500 12 7 0,000 0,01945928 0,06207538 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01945928 0,0619894 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01945928 0,06190366 ! retina homeostasis GO:0001895 9 7 0,000 0,01945928 0,06181816 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01945928 0,06173289 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01945928 0,06164786 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01945928 0,06156306 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01945928 0,0614785 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01945928 0,06139417 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01945928 0,06131007 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01945928 0,06122619 ! regulation of DNA binding GO:0051101 119 77 1,000 0,01970221 0,06190586 ! gland development GO:0048732 148 77 1,000 0,01970221 0,06182141 ! protein ubiquitination GO:0016567 125 77 1,000 0,01970221 0,06173718 ! T cell activation GO:0042110 134 79 1,000 0,02067264 0,0646899 ! forebrain development GO:0030900 131 80 1,000 0,02116525 0,0661414 ! hemostasis GO:0007599 125 81 1,000 0,02166274 0,06760422 ! mRNA transport GO:0051028 121 81 1,000 0,02166274 0,06751261 ! regulation of neurological system process GO:0031644 122 81 1,000 0,02166274 0,06742125 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02220872 0,06902711 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02220872 0,06893396 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02220872 0,06884106 ! axon extension GO:0048675 11 8 0,000 0,02220872 0,0687484 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02220872 0,068656 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02220872 0,06856384 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02220872 0,06847194 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02220872 0,06838027 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02220872 0,06828886 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02220872 0,06819768 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02220872 0,06810675 ! phosphate transport GO:0006817 10 8 0,000 0,02220872 0,06801606 ! N-glycan processing GO:0006491 12 8 0,000 0,02220872 0,06792562 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02220872 0,06783541 ! UTP metabolic process GO:0046051 8 8 0,000 0,02220872 0,06774544 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02220872 0,06765571 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02220872 0,06756622 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02220872 0,06747697 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02220872 0,06738795 ! succinate metabolic process GO:0006105 14 8 0,000 0,02220872 0,06729916 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02220872 0,06721061 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02220872 0,06712229 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02220872 0,0670342 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02220872 0,06694635 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02220872 0,06685872 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02220872 0,06677133 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02220872 0,06668416 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02220872 0,06659721 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02220872 0,0665105 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02220872 0,06642401 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02220872 0,06633775 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02220872 0,0662517 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02220872 0,06616589 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02220872 0,06608029 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02220872 0,06599491 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02220872 0,06590976 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02220872 0,06582482 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,02220872 0,06574011 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02220872 0,06565561 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02220872 0,06557133 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02220872 0,06548726 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02220872 0,06540341 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02220872 0,06531977 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02220872 0,06523635 ! melanin metabolic process GO:0006582 12 8 0,000 0,02220872 0,06515314 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02220872 0,06507014 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02220872 0,06498736 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02220872 0,06490478 ! macrophage activation GO:0042116 12 8 0,000 0,02220872 0,06482242 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02220872 0,06474026 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02220872 0,06465831 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02220872 0,06457657 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02220872 0,06449503 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02220872 0,0644137 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02220872 0,06433257 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02220872 0,06425165 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02220872 0,06417093 ! ruffle organization GO:0031529 11 8 0,000 0,02220872 0,06409042 ! osteoblast development GO:0002076 13 8 0,000 0,02220872 0,0640101 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02220872 0,06392999 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02220872 0,06385008 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02220872 0,06377037 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02220872 0,06369085 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02220872 0,06361154 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02220872 0,06353242 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02220872 0,0634535 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02220872 0,06337477 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02220872 0,06329624 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02220872 0,0632179 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02220872 0,06313976 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02220872 0,06306181 ! segment specification GO:0007379 10 8 0,000 0,02220872 0,06298405 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02220872 0,06290648 ! cellular extravasation GO:0045123 11 8 0,000 0,02220872 0,06282911 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02220872 0,06275192 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02220872 0,06267492 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02220872 0,06259812 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02220872 0,0625215 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02220872 0,06244507 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,02220872 0,06236882 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02220872 0,06229276 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02220872 0,06221689 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02220872 0,0621412 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02220872 0,06206569 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02220872 0,06199037 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02220872 0,06191523 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02220872 0,06184027 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02220872 0,06176549 ! icosanoid secretion GO:0032309 12 8 0,000 0,02220872 0,0616909 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02220872 0,06161648 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02220872 0,06154225 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02220872 0,06146819 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02220872 0,06139431 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02220872 0,0613206 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02220872 0,06124708 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02220872 0,06117373 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02220872 0,06110055 ! sterol catabolic process GO:0016127 9 8 0,000 0,02220872 0,06102756 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02220872 0,06095473 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02220872 0,06088208 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02220872 0,0608096 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02220872 0,06073729 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02220872 0,06066516 ! prophase GO:0051324 11 8 0,000 0,02220872 0,0605932 ! S phase GO:0051320 8 8 0,000 0,02220872 0,0605214 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02220872 0,06044978 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02220872 0,06037833 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02220872 0,06030704 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02220872 0,06023592 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02220872 0,06016498 ! hormone catabolic process GO:0042447 13 8 0,000 0,02220872 0,06009419 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02220872 0,06002358 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02220872 0,05995313 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02220872 0,05988284 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02220872 0,05981272 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02220872 0,05974276 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02220872 0,05967297 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02220872 0,05960334 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02220872 0,05953387 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02220872 0,05946457 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02220872 0,05939542 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02220872 0,05932644 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02220872 0,05925761 ! regulation of embryonic development GO:0045995 16 8 0,000 0,02220872 0,05918895 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02220872 0,05912044 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02220872 0,0590521 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02220872 0,05898391 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,02318426 0,06150379 ! regulation of protein localization GO:0032880 132 85 1,000 0,023701 0,0628022 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,02474869 0,06550285 GO:0060538|skeletal muscle organ development, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02495061 0,06596139 ! regulation of developmental growth GO:0048638 13 9 0,000 0,02495061 0,06588566 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,02495061 0,0658101 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02495061 0,06573472 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02495061 0,06565951 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02495061 0,06558447 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02495061 0,0655096 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02495061 0,0654349 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02495061 0,06536037 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02495061 0,06528602 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02495061 0,06521183 ! GTP metabolic process GO:0046039 9 9 0,000 0,02495061 0,06513781 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02495061 0,06506396 ! social behavior GO:0035176 14 9 0,000 0,02495061 0,06499027 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02495061 0,06491675 ! artery development GO:0060840 19 9 0,000 0,02495061 0,0648434 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02495061 0,06477021 ! regulation of glycolysis GO:0006110 15 9 0,000 0,02495061 0,06469719 ! response to pain GO:0048265 16 9 0,000 0,02495061 0,06462433 ! protein complex disassembly GO:0043241 17 9 0,000 0,02495061 0,06455164 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02495061 0,06447911 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02495061 0,06440674 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02495061 0,06433454 ! lung alveolus development GO:0048286 17 9 0,000 0,02495061 0,0642625 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02495061 0,06419061 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02495061 0,06411889 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02495061 0,06404733 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02495061 0,06397593 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02495061 0,06390469 ! protein targeting to ER GO:0045047 19 9 0,000 0,02495061 0,0638336 ! T cell selection GO:0045058 18 9 0,000 0,02495061 0,06376268 ! endoderm development GO:0007492 12 9 0,000 0,02495061 0,06369191 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02495061 0,0636213 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02495061 0,06355084 ! arginine catabolic process GO:0006527 10 9 0,000 0,02495061 0,06348054 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02495061 0,0634104 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02495061 0,06334041 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02495061 0,06327057 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02495061 0,06320089 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02495061 0,06313136 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02495061 0,06306199 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02495061 0,06299277 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02495061 0,06292369 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02495061 0,06285477 ! mannose metabolic process GO:0006013 9 9 0,000 0,02495061 0,06278601 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02495061 0,06271739 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02495061 0,06264892 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02495061 0,0625806 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02495061 0,06251243 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02495061 0,06244441 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02495061 0,06237653 ! motor axon guidance GO:0008045 14 9 0,000 0,02495061 0,0623088 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02495061 0,06224122 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02495061 0,06217379 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02495061 0,0621065 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02495061 0,06203936 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02495061 0,06197236 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02495061 0,06190551 ! DNA ligation GO:0006266 14 9 0,000 0,02495061 0,0618388 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02495061 0,06177224 ! response to amine stimulus GO:0014075 13 9 0,000 0,02495061 0,06170582 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02495061 0,06163954 ! erythrocyte development GO:0048821 11 9 0,000 0,02495061 0,0615734 ! renal water homeostasis GO:0003091 14 9 0,000 0,02495061 0,06150741 ! postreplication repair GO:0006301 11 9 0,000 0,02495061 0,06144155 ! mRNA cleavage GO:0006379 13 9 0,000 0,02495061 0,06137584 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02495061 0,06131027 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02495061 0,06124483 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02495061 0,06117954 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02495061 0,06111439 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02495061 0,06104937 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02495061 0,06098449 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02495061 0,06091975 ! acid secretion GO:0046717 14 9 0,000 0,02495061 0,06085515 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02495061 0,06079069 GO:0050879|multicellular organismal movement, ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02495061 0,06072636 ! oocyte differentiation GO:0009994 12 9 0,000 0,02495061 0,06066217 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02495061 0,06059811 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02495061 0,06053419 ! spleen development GO:0048536 15 9 0,000 0,02495061 0,0604704 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02495061 0,06040675 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02495061 0,06034323 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02495061 0,06027984 ! detection of calcium ion GO:0005513 13 9 0,000 0,02495061 0,06021659 ! blastocyst formation GO:0001825 12 9 0,000 0,02495061 0,06015347 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02495061 0,06009048 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02495061 0,06002762 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02495061 0,0599649 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02495061 0,05990231 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02495061 0,05983984 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02495061 0,05977751 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02495061 0,05971531 ! prepulse inhibition GO:0060134 14 9 0,000 0,02495061 0,05965323 ! embryonic placenta development GO:0001892 12 9 0,000 0,02495061 0,05959129 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02495061 0,05952947 ! insulin secretion GO:0030073 17 9 0,000 0,02495061 0,05946778 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02495061 0,05940622 ! response to nicotine GO:0035094 16 9 0,000 0,02495061 0,05934479 ! nucleus localization GO:0051647 15 9 0,000 0,02495061 0,05928348 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02495061 0,0592223 ! localization within membrane GO:0051668 15 9 0,000 0,02495061 0,05916125 ! reproductive developmental process GO:0003006 127 89 1,000 0,02581509 0,061148 ! leukocyte differentiation GO:0002521 143 90 1,000 0,02635524 0,06236323 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,02635524 0,06229913 ! hormone metabolic process GO:0042445 121 90 1,000 0,02635524 0,06223517 ! cell fate commitment GO:0045165 141 92 1,000 0,02744929 0,06475218 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02768497 0,06524122 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02768497 0,06517444 ! neuron fate specification GO:0048665 11 10 0,000 0,02768497 0,0651078 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02768497 0,0650413 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02768497 0,06497493 ! thyroid gland development GO:0030878 19 10 0,000 0,02768497 0,0649087 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02768497 0,0648426 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02768497 0,06477663 ! synapsis GO:0007129 13 10 0,000 0,02768497 0,0647108 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02768497 0,06464511 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02768497 0,06457954 ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02768497 0,06451411 ! sulfate transport GO:0008272 12 10 0,000 0,02768497 0,06444882 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02768497 0,06438365 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02768497 0,06431862 ! androgen metabolic process GO:0008209 13 10 0,000 0,02768497 0,06425371 ! phospholipid efflux GO:0033700 16 10 0,000 0,02768497 0,06418894 ! hippocampus development GO:0021766 19 10 0,000 0,02768497 0,0641243 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02768497 0,06405979 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02768497 0,06399541 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02768497 0,06393115 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02768497 0,06386703 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02768497 0,06380304 ! pathogenesis GO:0009405 13 10 0,000 0,02768497 0,06373917 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02768497 0,06367543 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02768497 0,06361182 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02768497 0,06354833 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02768497 0,06348498 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02768497 0,06342174 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02768497 0,06335864 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02768497 0,06329566 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02768497 0,0632328 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02768497 0,06317007 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02768497 0,06310746 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02768497 0,06304498 ! response to X-ray GO:0010165 16 10 0,000 0,02768497 0,06298262 ! B cell proliferation GO:0042100 14 10 0,000 0,02768497 0,06292039 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02768497 0,06285827 ! forebrain cell migration GO:0021885 17 10 0,000 0,02768497 0,06279628 ! lipid digestion GO:0044241 15 10 0,000 0,02768497 0,06273441 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02768497 0,06267267 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02768497 0,06261104 ! UV protection GO:0009650 14 10 0,000 0,02768497 0,06254954 ! entry into host cell GO:0030260 20 10 0,000 0,02768497 0,06248816 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02768497 0,06242689 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02768497 0,06236575 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02768497 0,06230473 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02768497 0,06224382 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02768497 0,06218304 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02768497 0,06212237 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02768497 0,06206182 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02768497 0,06200139 ! regulation of organ growth GO:0046620 11 10 0,000 0,02768497 0,06194108 ! response to dsRNA GO:0043331 18 10 0,000 0,02768497 0,06188088 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02768497 0,06182081 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02768497 0,06176084 ! embryonic axis specification GO:0000578 12 10 0,000 0,02768497 0,061701 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02768497 0,06164127 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02768497 0,06158165 ! cranial nerve development GO:0021545 12 10 0,000 0,02768497 0,06152215 ! fucose catabolic process GO:0019317 16 10 0,000 0,02768497 0,06146277 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02768497 0,0614035 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02768497 0,06134435 ! protein sumoylation GO:0016925 12 10 0,000 0,02768497 0,0612853 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02768497 0,06122638 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02768497 0,06116756 ! zymogen activation GO:0031638 14 10 0,000 0,02768497 0,06110886 ! salivary gland development GO:0007431 22 10 0,000 0,02768497 0,06105027 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02768497 0,06099179 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02768497 0,06093343 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02768497 0,06087517 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02768497 0,06081703 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02768497 0,060759 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02768497 0,06070108 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02768497 0,06064327 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02768497 0,06058557 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02768497 0,06052798 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02768497 0,06047049 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02768497 0,06041312 ! detection of bacterium GO:0016045 10 10 0,000 0,02768497 0,06035586 ! embryonic gut development GO:0048566 11 10 0,000 0,02768497 0,0602987 ! activation of innate immune response GO:0002218 10 10 0,000 0,02768497 0,06024166 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02768497 0,06018472 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02768497 0,06012788 ! developmental induction GO:0031128 13 10 0,000 0,02768497 0,06007116 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02768497 0,06001454 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02768497 0,05995803 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02768497 0,05990163 ! regulation of binding GO:0051098 151 95 1,000 0,02912431 0,06295669 ! angiogenesis GO:0001525 149 95 1,000 0,02912431 0,06289758 ! in utero embryonic development GO:0001701 147 96 1,000 0,02969159 0,06406253 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,02969159 0,06400249 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,03026329 0,06517375 ! rRNA transcription GO:0009303 17 11 0,000 0,03041181 0,06543234 ! respiratory burst GO:0045730 14 11 0,000 0,03041181 0,06537119 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03041181 0,06531015 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03041181 0,06524923 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03041181 0,06518842 ! virus-host interaction GO:0019048 17 11 0,000 0,03041181 0,06512772 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,03041181 0,06506714 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03041181 0,06500667 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03041181 0,06494631 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03041181 0,06488606 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03041181 0,06482593 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03041181 0,0647659 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03041181 0,06470599 ! mating GO:0007618 14 11 0,000 0,03041181 0,06464619 ! T cell proliferation GO:0042098 20 11 0,000 0,03041181 0,06458649 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03041181 0,06452691 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03041181 0,06446744 ! bone resorption GO:0045453 16 11 0,000 0,03041181 0,06440808 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03041181 0,06434883 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03041181 0,06428968 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03041181 0,06423065 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03041181 0,06417172 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03041181 0,0641129 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03041181 0,06405419 ! plasma membrane organization GO:0007009 18 11 0,000 0,03041181 0,06399558 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03041181 0,06393709 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03041181 0,0638787 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03041181 0,06382041 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03041181 0,06376224 ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03041181 0,06370417 ! adult heart development GO:0007512 11 11 0,000 0,03041181 0,0636462 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03041181 0,06358834 ! temperature homeostasis GO:0001659 16 11 0,000 0,03041181 0,06353058 ! L-glutamate transport GO:0015813 16 11 0,000 0,03041181 0,06347293 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03041181 0,06341539 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03041181 0,06335795 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03041181 0,06330061 ! stem cell development GO:0048864 29 11 0,000 0,03041181 0,06324338 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03041181 0,06318625 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03041181 0,06312922 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03041181 0,06307229 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03041181 0,06301547 ! vasoconstriction GO:0042310 15 11 0,000 0,03041181 0,06295875 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03041181 0,06290213 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03041181 0,06284562 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03041181 0,0627892 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03041181 0,06273289 ! ribosome assembly GO:0042255 13 11 0,000 0,03041181 0,06267668 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03041181 0,06262057 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03041181 0,06256456 ! chromatin silencing GO:0006342 19 11 0,000 0,03041181 0,06250864 ! nucleosome positioning GO:0016584 13 11 0,000 0,03041181 0,06245283 ! T cell homeostasis GO:0043029 20 11 0,000 0,03041181 0,06239712 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03041181 0,06234151 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03041181 0,062286 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03041181 0,06223058 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03041181 0,06217527 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03041181 0,06212005 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03041181 0,06206493 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03041181 0,06200991 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03041181 0,06195498 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03041181 0,06190015 ! male genitalia development GO:0030539 13 11 0,000 0,03041181 0,06184542 ! cholesterol efflux GO:0033344 19 11 0,000 0,03041181 0,06179079 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03041181 0,06173625 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03041181 0,06168181 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03041181 0,06162747 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03041181 0,06157322 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03041181 0,06151906 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03041181 0,061465 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,03041181 0,06141104 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,03041181 0,06135717 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03041181 0,0613034 ! lysogeny GO:0030069 18 11 0,000 0,03041181 0,06124971 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03041181 0,06119613 ! acrosome reaction GO:0007340 13 11 0,000 0,03041181 0,06114263 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03041181 0,06108923 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,03200464 0,06423269 ! lactation GO:0007595 20 12 0,000 0,03313117 0,06643565 ! reproductive cellular process GO:0048610 14 12 0,000 0,03313117 0,06637778 ! tRNA modification GO:0006400 14 12 0,000 0,03313117 0,06632001 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03313117 0,06626234 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03313117 0,06620477 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,03313117 0,0661473 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03313117 0,06608993 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03313117 0,06603266 ! non-recombinational repair GO:0000726 19 12 0,000 0,03313117 0,06597549 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03313117 0,06591841 ! peroxisomal transport GO:0043574 21 12 0,000 0,03313117 0,06586144 ! cartilage condensation GO:0001502 18 12 0,000 0,03313117 0,06580456 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03313117 0,06574779 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03313117 0,06569111 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03313117 0,06563453 ! heart looping GO:0001947 15 12 0,000 0,03313117 0,06557804 ! palate development GO:0060021 15 12 0,000 0,03313117 0,06552166 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03313117 0,06546537 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03313117 0,06540917 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03313117 0,06535308 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03313117 0,06529707 ! arginine metabolic process GO:0006525 13 12 0,000 0,03313117 0,06524117 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03313117 0,06518536 ! methionine metabolic process GO:0006555 13 12 0,000 0,03313117 0,06512965 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03313117 0,06507403 ! Golgi organization GO:0007030 18 12 0,000 0,03313117 0,0650185 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03313117 0,06496307 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03313117 0,06490774 ! monoamine transport GO:0015844 13 12 0,000 0,03313117 0,0648525 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03313117 0,06479735 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,03313117 0,0647423 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03313117 0,06468734 ! L-amino acid transport GO:0015807 20 12 0,000 0,03313117 0,06463247 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03313117 0,0645777 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03313117 0,06452302 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03313117 0,06446843 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03313117 0,06441394 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03313117 0,06435953 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03313117 0,06430522 ! cerebellum development GO:0021549 13 12 0,000 0,03313117 0,064251 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03313117 0,06419687 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03313117 0,06414283 ! histone acetylation GO:0016573 23 12 0,000 0,03313117 0,06408889 ! histone methylation GO:0016571 15 12 0,000 0,03313117 0,06403503 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03313117 0,06398126 ! gland morphogenesis GO:0022612 23 12 0,000 0,03313117 0,06392759 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03313117 0,063874 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,03313117 0,06382051 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03313117 0,0637671 ! response to gamma radiation GO:0010332 20 12 0,000 0,03313117 0,06371378 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03313117 0,06366056 ! intestinal absorption GO:0050892 19 12 0,000 0,03313117 0,06360742 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03313117 0,06355437 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03313117 0,06350141 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03313117 0,06344853 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03313117 0,06339575 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03313117 0,06334305 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03313117 0,06329044 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03313117 0,06323791 ! microspike assembly GO:0030035 23 12 0,000 0,03313117 0,06318548 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03313117 0,06313313 ! response to cold GO:0009409 14 12 0,000 0,03313117 0,06308087 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,03584305 0,06818777 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,03584305 0,06813142 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,03584305 0,06807516 ! cGMP metabolic process GO:0046068 16 13 0,000 0,03584305 0,06801899 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,03584305 0,06796291 ! water transport GO:0006833 17 13 0,000 0,03584305 0,06790693 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,03584305 0,06785104 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,03584305 0,06779524 ! lipid localization GO:0010876 24 13 0,000 0,03584305 0,06773954 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,03584305 0,06768392 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,03584305 0,0676284 ! organelle fusion GO:0048284 28 13 0,000 0,03584305 0,06757296 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,03584305 0,06751762 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,03584305 0,06746237 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,03584305 0,06740721 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,03584305 0,06735214 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,03584305 0,06729715 ! response to hexose stimulus GO:0009746 19 13 0,000 0,03584305 0,06724226 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,03584305 0,06718746 ! glutamate metabolic process GO:0006536 18 13 0,000 0,03584305 0,06713275 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,03584305 0,06707812 ! cytokine metabolic process GO:0042107 17 13 0,000 0,03584305 0,06702359 ! NAD metabolic process GO:0019674 21 13 0,000 0,03584305 0,06696914 ! exocrine system development GO:0035272 27 13 0,000 0,03584305 0,06691478 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,03584305 0,06686051 ! bone mineralization GO:0030282 15 13 0,000 0,03584305 0,06680633 ! regulation of exocytosis GO:0017157 17 13 0,000 0,03584305 0,06675224 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,03584305 0,06669823 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,03584305 0,06664431 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,03584305 0,06659048 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,03584305 0,06653673 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,03584305 0,06648308 ! genitalia development GO:0048806 15 13 0,000 0,03584305 0,0664295 ! regulation of cellular pH GO:0030641 20 13 0,000 0,03584305 0,06637602 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,03584305 0,06632262 ! cellular pigmentation GO:0033059 24 13 0,000 0,03584305 0,0662693 ! tissue regeneration GO:0042246 21 13 0,000 0,03584305 0,06621608 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,03584305 0,06616293 ! cofactor transport GO:0051181 19 13 0,000 0,03584305 0,06610987 ! NADP metabolic process GO:0006739 18 13 0,000 0,03584305 0,0660569 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,03584305 0,06600401 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,03584305 0,06595121 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03584305 0,06589849 ! gas transport GO:0015669 18 13 0,000 0,03584305 0,06584586 ! regulation of RNA stability GO:0043487 28 13 0,000 0,03584305 0,06579331 ! heme biosynthetic process GO:0006783 20 13 0,000 0,03584305 0,06574084 ! regulation of axon extension GO:0030516 23 13 0,000 0,03584305 0,06568846 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,03584305 0,06563616 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,03584305 0,06558394 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,03584305 0,06553181 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,03584305 0,06547976 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,03584305 0,06542779 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,03584305 0,0653759 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,03854748 0,07025293 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,03854748 0,07019731 ! superoxide anion generation GO:0042554 18 14 0,000 0,03854748 0,07014177 ! regulation of S phase GO:0033261 18 14 0,000 0,03854748 0,07008633 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,03854748 0,07003097 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,03854748 0,06997569 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,03854748 0,06992051 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,03854748 0,06986541 ! inositol metabolic process GO:0006020 20 14 0,000 0,03854748 0,0698104 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,03854748 0,06975547 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,03854748 0,06970063 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,03854748 0,06964588 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,03854748 0,06959121 ! gene silencing by RNA GO:0031047 20 14 0,000 0,03854748 0,06953663 ! response to cAMP GO:0051591 19 14 0,000 0,03854748 0,06948213 ! limbic system development GO:0021761 25 14 0,000 0,03854748 0,06942772 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,03854748 0,0693734 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,03854748 0,06931916 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,03854748 0,069265 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,03854748 0,06921093 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,03854748 0,06915694 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,03854748 0,06910304 ! glycine metabolic process GO:0006544 22 14 0,000 0,03854748 0,06904922 ! pituitary gland development GO:0021983 23 14 0,000 0,03854748 0,06899549 ! cellular response to starvation GO:0009267 21 14 0,000 0,03854748 0,06894184 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,03854748 0,06888827 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,03854748 0,06883479 ! regulation of heart rate GO:0002027 23 14 0,000 0,03854748 0,06878138 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,03854748 0,06872806 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,03854748 0,06867483 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,03854748 0,06862167 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,03854748 0,0685686 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,03854748 0,06851561 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,03854748 0,06846271 ! intermediate filament-based process GO:0045103 24 14 0,000 0,03854748 0,06840988 ! axon cargo transport GO:0008088 27 14 0,000 0,03854748 0,06835713 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,03854748 0,06830447 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,03854748 0,06825189 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,03854748 0,06819939 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,03854748 0,06814697 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03854748 0,06809463 ! mRNA splice site selection GO:0006376 26 14 0,000 0,03854748 0,06804237 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,03854748 0,06799019 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,03854748 0,06793809 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,03854748 0,06788607 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,03854748 0,06783413 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,03854748 0,06778227 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,03854748 0,06773048 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,03854748 0,06767878 ! muscle maintenance GO:0046716 19 14 0,000 0,03854748 0,06762716 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,03854748 0,06757561 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,03854748 0,06752415 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,03854748 0,06747276 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,03854748 0,06742145 ! cell killing GO:0001906 20 14 0,000 0,03854748 0,06737022 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,03854748 0,06731906 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,03854748 0,06726798 ! cilium assembly GO:0042384 20 14 0,000 0,03854748 0,06721699 ! peptide hormone secretion GO:0030072 23 14 0,000 0,03854748 0,06716606 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,04124448 0,07181098 ! positive regulation of cell size GO:0045793 20 15 0,000 0,04124448 0,07175666 ! metencephalon development GO:0022037 19 15 0,000 0,04124448 0,07170242 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,04124448 0,07164826 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,04124448 0,07159419 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,04124448 0,0715402 ! skin development GO:0043588 25 15 0,000 0,04124448 0,07148629 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,04124448 0,07143246 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,04124448 0,07137871 ! lipid phosphorylation GO:0046834 23 15 0,000 0,04124448 0,07132504 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,04124448 0,07127145 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,04124448 0,07121794 ! bile acid metabolic process GO:0008206 22 15 0,000 0,04124448 0,07116452 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,04124448 0,07111117 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,04124448 0,0710579 ! adult walking behavior GO:0007628 25 15 0,000 0,04124448 0,07100472 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,04124448 0,07095161 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,04124448 0,07089858 ! myoblast differentiation GO:0045445 27 15 0,000 0,04124448 0,07084563 ! centrosome cycle GO:0007098 16 15 0,000 0,04124448 0,07079276 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,04124448 0,07073997 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,04124448 0,07068726 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,04124448 0,07063462 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,04124448 0,07058207 ! cerebral cortex development GO:0021987 29 15 0,000 0,04124448 0,07052959 ! response to osmotic stress GO:0006970 22 15 0,000 0,04124448 0,07047719 ! vesicle coating GO:0006901 25 15 0,000 0,04124448 0,07042487 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,04124448 0,07037263 ! DNA integration GO:0015074 22 15 0,000 0,04124448 0,07032046 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,04124448 0,07026837 ! peptide secretion GO:0002790 27 15 0,000 0,04124448 0,07021636 ! regulation of vasodilation GO:0042312 24 15 0,000 0,04124448 0,07016442 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,04124448 0,07011257 ! neuron recognition GO:0008038 22 15 0,000 0,04124448 0,07006078 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,04124448 0,07000908 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,04124448 0,06995745 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,04124448 0,0699059 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,04124448 0,06985442 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,04124448 0,06980302 ! biomineral formation GO:0031214 18 15 0,000 0,04124448 0,06975169 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,04124448 0,06970044 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,04124448 0,06964927 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,04124448 0,06959817 ! dopamine metabolic process GO:0042417 30 15 0,000 0,04124448 0,06954714 ! organic cation transport GO:0015695 19 15 0,000 0,04124448 0,06949619 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,04124448 0,06944532 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,04124448 0,06939451 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,04124448 0,06934379 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,04124448 0,06929313 ! defense response to virus GO:0051607 27 15 0,000 0,04124448 0,06924256 ! peptide hormone processing GO:0016486 19 15 0,000 0,04124448 0,06919205 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,04124448 0,06914162 ! protein secretion GO:0009306 27 16 0,000 0,04393407 0,07359676 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,04393407 0,0735432 ! hormone secretion GO:0046879 25 16 0,000 0,04393407 0,07348971 ! bone remodeling GO:0046849 24 16 0,000 0,04393407 0,0734363 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04393407 0,07338297 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,04393407 0,07332972 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04393407 0,07327654 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04393407 0,07322344 ! glial cell development GO:0021782 24 16 0,000 0,04393407 0,07317042 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04393407 0,07311748 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04393407 0,07306461 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04393407 0,07301181 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04393407 0,0729591 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04393407 0,07290646 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04393407 0,07285389 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04393407 0,07280141 ! fructose metabolic process GO:0006000 20 16 0,000 0,04393407 0,07274899 ! regulation of protein binding GO:0043393 27 16 0,000 0,04393407 0,07269666 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04393407 0,07264439 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04393407 0,07259221 ! protein export from nucleus GO:0006611 24 16 0,000 0,04393407 0,07254009 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04393407 0,07248806 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04393407 0,07243609 ! DNA replication initiation GO:0006270 25 16 0,000 0,04393407 0,07238421 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04393407 0,07233239 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04393407 0,07228065 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04393407 0,07222899 ! diencephalon development GO:0021536 25 16 0,000 0,04393407 0,07217739 ! oogenesis GO:0048477 23 16 0,000 0,04393407 0,07212588 ! neural crest cell migration GO:0001755 24 16 0,000 0,04393407 0,07207443 ! G1 phase GO:0051318 27 16 0,000 0,04393407 0,07202306 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04393407 0,07197176 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04393407 0,07192053 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04393407 0,07186938 ! steroid catabolic process GO:0006706 22 16 0,000 0,04393407 0,0718183 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04393407 0,07176729 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,04393407 0,07171636 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,04393407 0,0716655 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04393407 0,07161471 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04393407 0,07156399 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04393407 0,07151334 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04393407 0,07146277 ! nerve development GO:0021675 18 16 0,000 0,04393407 0,07141226 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04393407 0,07136183 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04393407 0,07131147 ! negative regulation of translation GO:0017148 22 16 0,000 0,04393407 0,07126118 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,04661626 0,07555842 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,04661626 0,07550521 ! negative regulation of defense response GO:0031348 19 17 0,000 0,04661626 0,07545208 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,04661626 0,07539902 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,04661626 0,07534603 ! glycerol metabolic process GO:0006071 20 17 0,000 0,04661626 0,07529312 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,04661626 0,07524028 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,04661626 0,07518752 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,04661626 0,07513483 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,04661626 0,07508221 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,04661626 0,07502967 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,04661626 0,0749772 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,04661626 0,07492481 ! memory GO:0007613 25 17 0,000 0,04661626 0,07487249 ! keratinization GO:0031424 17 17 0,000 0,04661626 0,07482024 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,04661626 0,07476806 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,04661626 0,07471596 ! retinoid metabolic process GO:0001523 22 17 0,000 0,04661626 0,07466393 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,04661626 0,07461197 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,04661626 0,07456008 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,04661626 0,07450827 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,04661626 0,07445653 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,04661626 0,07440486 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,04661626 0,07435326 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,04661626 0,07430173 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,04661626 0,07425028 ! membrane budding GO:0006900 29 17 0,000 0,04661626 0,07419889 ! heme metabolic process GO:0042168 27 17 0,000 0,04661626 0,07414758 ! neuromuscular junction development GO:0007528 23 17 0,000 0,04661626 0,07409634 ! body fluid secretion GO:0007589 27 17 0,000 0,04661626 0,07404517 ! stem cell differentiation GO:0048863 36 17 0,000 0,04661626 0,07399407 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,04661626 0,07394304 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,04661626 0,07389208 ! sensory perception of pain GO:0019233 23 17 0,000 0,04661626 0,07384119 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,04661626 0,07379037 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,04661626 0,07373962 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,04661626 0,07368894 ! synaptogenesis GO:0007416 24 17 0,000 0,04661626 0,07363833 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,04661626 0,07358778 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,04661626 0,07353731 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,04661626 0,07348691 ! cell-cell junction organization GO:0045216 25 17 0,000 0,04661626 0,07343658 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,04661626 0,07338631 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,04661626 0,07333612 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,04661626 0,07328599 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,04661626 0,07323593 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,04661626 0,07318594 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,04661626 0,07313602 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,04929109 0,07727982 ! positive regulation of translation GO:0045727 28 18 0,000 0,04929109 0,07722718 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,04929109 0,07717461 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,04929109 0,07712211 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,04929109 0,07706968 ! cAMP metabolic process GO:0046058 33 18 0,000 0,04929109 0,07701732 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,04929109 0,07696504 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,04929109 0,07691282 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,04929109 0,07686068 ! axis specification GO:0009798 26 18 0,000 0,04929109 0,0768086 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,04929109 0,0767566 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,04929109 0,07670467 ! pancreas development GO:0031016 26 18 0,000 0,04929109 0,0766528 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,04929109 0,07660101 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,04929109 0,07654929 ! response to retinoic acid GO:0032526 25 18 0,000 0,04929109 0,07649764 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,04929109 0,07644605 ! fucose metabolic process GO:0006004 26 18 0,000 0,04929109 0,07639454 ! response to fungus GO:0009620 19 18 0,000 0,04929109 0,0763431 ! peptide cross-linking GO:0018149 31 18 0,000 0,04929109 0,07629172 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,04929109 0,07624041 ! heart process GO:0003015 27 18 0,000 0,04929109 0,07618918 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,04929109 0,07613801 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,04929109 0,07608691 ! somitogenesis GO:0001756 24 18 0,000 0,04929109 0,07603588 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,04929109 0,07598492 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,04929109 0,07593402 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,04929109 0,0758832 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,04929109 0,07583244 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,04929109 0,07578175 ! vitamin transport GO:0051180 24 18 0,000 0,04929109 0,07573113 ! hormone transport GO:0009914 27 18 0,000 0,04929109 0,07568057 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,04929109 0,07563008 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,04929109 0,07557966 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,04929109 0,07552931 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,04929109 0,07547903 ! cell-cell recognition GO:0009988 20 18 0,000 0,04929109 0,07542881 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,04929109 0,07537865 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,04929109 0,07532857 ! regulation of glucose import GO:0046324 21 18 0,000 0,04929109 0,07527855 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,04929109 0,0752286 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,04929109 0,07517871 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,04929109 0,07512889 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,04929109 0,07507914 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,05195856 0,0790898 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,05195856 0,07903749 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,05195856 0,07898525 ! positive regulation of ossification GO:0045778 30 19 0,000 0,05195856 0,07893308 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,05195856 0,07888098 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,05195856 0,07882895 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,05195856 0,07877698 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,05195856 0,07872509 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,05195856 0,07867326 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,05195856 0,0786215 ! regeneration GO:0031099 32 19 0,000 0,05195856 0,07856981 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,05195856 0,07851819 ! response to alkaloid GO:0043279 32 19 0,000 0,05195856 0,07846663 ! sensory perception of taste GO:0050909 23 19 0,000 0,05195856 0,07841515 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,05195856 0,07836373 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,05195856 0,07831237 ! smooth muscle contraction GO:0006939 36 19 0,000 0,05195856 0,07826109 ! peroxisome organization GO:0007031 29 19 0,000 0,05195856 0,07820987 ! digestive system process GO:0022600 30 19 0,000 0,05195856 0,07815872 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,05195856 0,07810764 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,05195856 0,07805662 ! response to vitamin A GO:0033189 26 19 0,000 0,05195856 0,07800567 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,05195856 0,07795478 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,05195856 0,07790397 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,05195856 0,07785321 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,05195856 0,07780253 ! response to starvation GO:0042594 30 19 0,000 0,05195856 0,07775191 ! sex determination GO:0007530 29 19 0,000 0,05195856 0,07770135 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,05195856 0,07765087 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,05195856 0,07760044 ! cytolysis GO:0019835 20 19 0,000 0,05195856 0,07755009 ! renal system process GO:0003014 35 19 0,000 0,05195856 0,07749979 ! vasodilation GO:0042311 33 19 0,000 0,05195856 0,07744957 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,05195856 0,07739941 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,05195856 0,07734931 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,05195856 0,07729928 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,05195856 0,07724931 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,05195856 0,07719941 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,05195856 0,07714957 ! sarcomere organization GO:0045214 23 19 0,000 0,05195856 0,0770998 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,05195856 0,07705009 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,05195856 0,07700044 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,05195856 0,07695086 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,05195856 0,07690134 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,05195856 0,07685189 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,05195856 0,0768025 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,05195856 0,07675317 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0546187 0,08063094 ! iron ion transport GO:0006826 37 20 0,000 0,0546187 0,08057922 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0546187 0,08052757 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0546187 0,08047598 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0546187 0,08042446 ! response to vitamin GO:0033273 29 20 0,000 0,0546187 0,080373 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0546187 0,08032162 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,0546187 0,08027029 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0546187 0,08021903 ! spinal cord development GO:0021510 31 20 0,000 0,0546187 0,08016784 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0546187 0,08011671 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,0546187 0,08006565 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0546187 0,08001465 ! chromosome condensation GO:0030261 31 20 0,000 0,0546187 0,07996372 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0546187 0,07991285 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0546187 0,07986205 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0546187 0,07981131 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0546187 0,07976064 ! pallium development GO:0021543 38 20 0,000 0,0546187 0,07971003 ! DNA modification GO:0006304 28 20 0,000 0,0546187 0,07965948 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,0546187 0,079609 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,0546187 0,07955859 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,0546187 0,07950823 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0546187 0,07945794 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0546187 0,07940772 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,0546187 0,07935755 ! collagen catabolic process GO:0030574 25 20 0,000 0,0546187 0,07930745 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0546187 0,07925742 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0546187 0,07920744 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0546187 0,07915753 ! alditol metabolic process GO:0019400 24 20 0,000 0,0546187 0,07910769 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,05727153 0,08289774 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,05727153 0,0828456 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,05727153 0,08279353 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,05727153 0,08274153 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,05727153 0,08268959 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,05727153 0,08263771 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,05727153 0,0825859 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,05727153 0,08253415 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,05727153 0,08248247 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,05727153 0,08243086 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,05727153 0,08237931 ! protein amino acid acylation GO:0043543 37 21 0,000 0,05727153 0,08232782 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,05727153 0,0822764 ! vesicle docking GO:0048278 27 21 0,000 0,05727153 0,08222504 ! phototransduction GO:0007602 25 21 0,000 0,05727153 0,08217374 ! dendrite development GO:0016358 35 21 0,000 0,05727153 0,08212251 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,05727153 0,08207135 ! ovarian follicle development GO:0001541 30 21 0,000 0,05727153 0,08202024 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,05727153 0,0819692 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,05727153 0,08191823 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,05727153 0,08186732 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,05727153 0,08181647 ! cell aging GO:0007569 32 21 0,000 0,05727153 0,08176568 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,05727153 0,08171496 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,05727153 0,0816643 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,05727153 0,0816137 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,05727153 0,08156316 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,05727153 0,08151269 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,05727153 0,08146228 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,05727153 0,08141193 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,05727153 0,08136165 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,05727153 0,08131143 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,05727153 0,08126127 ! fatty acid transport GO:0015908 30 21 0,000 0,05727153 0,08121117 ! immunoglobulin production GO:0002377 33 21 0,000 0,05727153 0,08116113 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,05727153 0,08111115 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,05727153 0,08106124 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,05727153 0,08101138 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,05727153 0,08096159 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,05727153 0,08091186 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,05727153 0,08086219 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,05727153 0,08081258 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,05727153 0,08076304 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,05727153 0,08071355 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,05727153 0,08066412 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,05727153 0,08061476 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,05727153 0,08056545 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,05727153 0,0805162 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,05727153 0,08046702 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,05727153 0,08041789 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,05991706 0,08408129 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,05991706 0,08403003 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,05991706 0,08397882 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,05991706 0,08392767 ! viral genome replication GO:0019079 29 22 0,000 0,05991706 0,08387659 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,05991706 0,08382557 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,05991706 0,08377462 ! leukocyte adhesion GO:0007159 38 22 0,000 0,05991706 0,08372372 ! molting cycle process GO:0022404 40 22 0,000 0,05991706 0,08367289 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,05991706 0,08362211 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,05991706 0,0835714 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,05991706 0,08352075 ! vasculogenesis GO:0001570 33 22 0,000 0,05991706 0,08347016 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,05991706 0,08341964 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,05991706 0,08336917 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,05991706 0,08331877 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,05991706 0,08326842 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,05991706 0,08321814 ! lysosome organization GO:0007040 37 22 0,000 0,05991706 0,08316792 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,05991706 0,08311776 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,05991706 0,08306766 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,05991706 0,08301762 ! regulation of behavior GO:0050795 38 22 0,000 0,05991706 0,08296764 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,05991706 0,08291771 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,05991706 0,08286785 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,05991706 0,08281805 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,05991706 0,08276831 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,05991706 0,08271863 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,05991706 0,08266901 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,05991706 0,08261945 ! blastocyst development GO:0001824 37 22 0,000 0,05991706 0,08256995 ! neural tube closure GO:0001843 33 22 0,000 0,05991706 0,0825205 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,05991706 0,08247112 ! protein tetramerization GO:0051262 39 22 0,000 0,05991706 0,0824218 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06255532 0,08599955 ! neuron fate commitment GO:0048663 32 23 0,000 0,06255532 0,08594818 ! embryonic pattern specification GO:0009880 31 23 0,000 0,06255532 0,08589686 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,06255532 0,08584561 ! myelination GO:0042552 35 23 0,000 0,06255532 0,08579442 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06255532 0,08574329 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06255532 0,08569223 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,06255532 0,08564122 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,06255532 0,08559027 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,06255532 0,08553939 ! vesicle targeting GO:0006903 32 23 0,000 0,06255532 0,08548856 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06255532 0,08543779 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,06255532 0,08538709 ! osteoblast differentiation GO:0001649 40 23 0,000 0,06255532 0,08533644 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06255532 0,08528586 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06255532 0,08523534 ! interaction with host GO:0051701 37 23 0,000 0,06255532 0,08518487 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06255532 0,08513447 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,06255532 0,08508412 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,06255532 0,08503383 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,06255532 0,08498361 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,06255532 0,08493344 ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06255532 0,08488333 ! cell fate determination GO:0001709 45 23 0,000 0,06255532 0,08483328 ! pentose metabolic process GO:0019321 31 23 0,000 0,06255532 0,08478329 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,06255532 0,08473336 ! spermatid development GO:0007286 33 23 0,000 0,06255532 0,08468349 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06255532 0,08463367 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06255532 0,08458392 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06255532 0,08453422 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06255532 0,08448458 ! telomere organization GO:0032200 32 23 0,000 0,06255532 0,084435 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06255532 0,08438548 ! regulation of amine transport GO:0051952 38 23 0,000 0,06255532 0,08433602 ! liver development GO:0001889 40 23 0,000 0,06255532 0,08428661 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,06518633 0,08778019 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,06518633 0,08772883 ! initiation of viral infection GO:0019059 42 24 0,000 0,06518633 0,08767752 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,06518633 0,08762628 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,06518633 0,0875751 ! superoxide metabolic process GO:0006801 32 24 0,000 0,06518633 0,08752397 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,06518633 0,08747291 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,06518633 0,08742191 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,06518633 0,08737096 ! fat cell differentiation GO:0045444 37 24 0,000 0,06518633 0,08732007 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,06518633 0,08726925 ! sperm motility GO:0030317 27 24 0,000 0,06518633 0,08721848 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,06518633 0,08716777 ! vacuole organization GO:0007033 39 24 0,000 0,06518633 0,08711712 ! neural crest cell development GO:0014032 39 24 0,000 0,06518633 0,08706653 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,06518633 0,087016 ! primary neural tube formation GO:0014020 35 24 0,000 0,06518633 0,08696553 ! negative regulation of cell development GO:0010721 56 24 0,000 0,06518633 0,08691511 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,06518633 0,08686476 ! base-excision repair GO:0006284 31 24 0,000 0,06518633 0,08681446 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,06518633 0,08676422 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,06518633 0,08671404 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,06518633 0,08666391 ! glutathione metabolic process GO:0006749 29 24 0,000 0,06518633 0,08661385 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,06518633 0,08656384 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,06518633 0,08651389 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,06518633 0,08646399 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,06781011 0,08989236 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,06781011 0,08984058 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,06781011 0,08978886 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,06781011 0,0897372 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,06781011 0,0896856 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,06781011 0,08963405 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,06781011 0,08958257 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,06781011 0,08953114 ! peptide transport GO:0015833 43 25 0,000 0,06781011 0,08947978 ! male gonad development GO:0008584 33 25 0,000 0,06781011 0,08942847 ! iron ion homeostasis GO:0055072 39 25 0,000 0,06781011 0,08937722 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,06781011 0,08932603 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,06781011 0,0892749 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,06781011 0,08922383 ! phospholipid transport GO:0015914 35 25 0,000 0,06781011 0,08917281 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,06781011 0,08912186 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,06781011 0,08907096 ! detection of light stimulus GO:0009583 30 25 0,000 0,06781011 0,08902012 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,06781011 0,08896934 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,06781011 0,08891861 ! leukocyte proliferation GO:0070661 39 25 0,000 0,06781011 0,08886795 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,07042667 0,0922445 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,07042667 0,092192 ! translational initiation GO:0006413 43 26 0,000 0,07042667 0,09213956 ! regulation of pH GO:0006885 36 26 0,000 0,07042667 0,09208717 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,07042667 0,09203485 ! circadian rhythm GO:0007623 42 26 0,000 0,07042667 0,09198259 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,07042667 0,09193039 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,07042667 0,09187824 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,07042667 0,09182616 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,07042667 0,09177413 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,07042667 0,09172216 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,07042667 0,09167026 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,07042667 0,09161841 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,07042667 0,09156661 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,07042667 0,09151488 ! regulation of coagulation GO:0050818 39 26 0,000 0,07042667 0,09146321 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,07303604 0,09479847 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,07303604 0,094745 ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,07303604 0,09469159 ! membrane docking GO:0022406 39 27 0,000 0,07303604 0,09463824 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,07303604 0,09458496 ! catechol metabolic process GO:0009712 43 27 0,000 0,07303604 0,09453173 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,07303604 0,09447856 ! acute-phase response GO:0006953 42 27 0,000 0,07303604 0,09442545 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,07303604 0,09437241 ! myofibril assembly GO:0030239 36 27 0,000 0,07303604 0,09431942 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,07303604 0,09426649 ! response to ionizing radiation GO:0010212 47 27 0,000 0,07303604 0,09421362 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,07303604 0,09416081 ! natural killer cell activation GO:0030101 35 27 0,000 0,07303604 0,09410806 ! lipid oxidation GO:0034440 38 27 0,000 0,07303604 0,09405537 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,07303604 0,09400273 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,07303604 0,09395016 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,07303604 0,09389764 ! gene silencing GO:0016458 41 27 0,000 0,07303604 0,09384519 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,07563823 0,09713452 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,07563823 0,09708031 ! phenol metabolic process GO:0018958 44 28 0,000 0,07563823 0,09702617 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,07563823 0,09697208 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,07563823 0,09691806 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,07563823 0,0968641 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,07563823 0,0968102 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,07563823 0,09675635 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,07563823 0,09670257 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,07563823 0,09664884 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,07563823 0,09659518 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,07563823 0,09654158 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,07563823 0,09648803 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,07563823 0,09643455 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,07563823 0,09638112 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,07563823 0,09632775 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,07563823 0,09627444 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,07563823 0,09622119 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,07563823 0,096168 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,07563823 0,09611487 ! ensheathment of neurons GO:0007272 43 28 0,000 0,07563823 0,0960618 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,07563823 0,09600879 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,07563823 0,09595583 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,07563823 0,09590293 ! neural tube formation GO:0001841 41 28 0,000 0,07563823 0,09585009 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,07563823 0,09579731 ! placenta development GO:0001890 37 28 0,000 0,07563823 0,09574459 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,07823326 0,09897497 ! regulation of innate immune response GO:0045088 38 29 0,000 0,07823326 0,09892056 ! ovulation cycle process GO:0022602 41 29 0,000 0,07823326 0,09886621 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,07823326 0,09881192 ! protein targeting to membrane GO:0006612 53 29 0,000 0,07823326 0,09875768 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,07823326 0,09870351 ! mismatch repair GO:0006298 34 29 0,000 0,07823326 0,0986494 ! muscle cell development GO:0055001 38 29 0,000 0,07823326 0,09859534 ! telencephalon development GO:0021537 52 29 0,000 0,07823326 0,09854135 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,07823326 0,09848741 ! eye morphogenesis GO:0048592 51 29 0,000 0,07823326 0,09843353 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,07823326 0,09837972 ! tissue homeostasis GO:0001894 42 29 0,000 0,07823326 0,09832596 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,08082116 0,10152303 ! collagen metabolic process GO:0032963 40 30 0,000 0,08082116 0,10146761 ! organic anion transport GO:0015711 51 30 0,000 0,08082116 0,10141225 ! cholesterol transport GO:0030301 46 30 0,000 0,08082116 0,10135696 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,08082116 0,10130172 ! spliceosome assembly GO:0000245 49 30 0,000 0,08082116 0,10124655 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,08082116 0,10119143 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,08082116 0,10113638 ! ceramide metabolic process GO:0006672 43 30 0,000 0,08082116 0,10108138 ! ovulation cycle GO:0042698 43 30 0,000 0,08082116 0,10102645 ! hindbrain development GO:0030902 45 30 0,000 0,08082116 0,10097157 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,08082116 0,10091676 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,08082116 0,100862 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,08082116 0,1008073 ! response to heat GO:0009408 41 30 0,000 0,08082116 0,10075266 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,08082116 0,10069808 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,08082116 0,10064356 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,08340194 0,10380111 ! negative regulation of secretion GO:0051048 49 31 0,000 0,08340194 0,10374497 ! mammary gland development GO:0030879 57 31 0,000 0,08340194 0,10368889 ! glial cell differentiation GO:0010001 55 31 0,000 0,08340194 0,10363288 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,08340194 0,10357692 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,08340194 0,10352102 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,08340194 0,10346519 ! odontogenesis GO:0042476 50 31 0,000 0,08340194 0,10340941 ! segmentation GO:0035282 41 31 0,000 0,08340194 0,10335369 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,08340194 0,10329804 ! metanephros development GO:0001656 58 31 0,000 0,08340194 0,10324244 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,08340194 0,1031869 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,08340194 0,10313143 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,08340194 0,10307601 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,08340194 0,10302065 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,08340194 0,10296535 ! RNA modification GO:0009451 40 31 0,000 0,08340194 0,10291012 ! regulation of muscle development GO:0048634 48 32 0,000 0,08597562 0,10602891 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,08597562 0,10597209 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,08597562 0,10591533 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,08597562 0,10585863 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,08597562 0,10580199 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,08597562 0,10574541 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,08597562 0,10568889 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,08597562 0,10563244 ! peripheral nervous system development GO:0007422 53 32 0,000 0,08597562 0,10557604 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,08597562 0,1055197 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,08597562 0,10546342 ! cytokine production GO:0001816 44 32 0,000 0,08597562 0,10540721 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,08597562 0,10535105 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,08597562 0,10529495 ! vesicle localization GO:0051648 47 32 0,000 0,08597562 0,10523892 ! RNA export from nucleus GO:0006405 44 33 0,000 0,08854222 0,10832293 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,08854222 0,10826534 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,08854222 0,10820781 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,08854222 0,10815035 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,08854222 0,10809294 ! sister chromatid segregation GO:0000819 46 33 0,000 0,08854222 0,1080356 ! ear morphogenesis GO:0042471 42 33 0,000 0,08854222 0,10797832 ! actomyosin structure organization GO:0031032 43 33 0,000 0,08854222 0,10792109 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,08854222 0,10786393 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,08854222 0,10780683 ! nucleus organization GO:0006997 49 33 0,000 0,08854222 0,10774979 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,08854222 0,10769281 ! female gonad development GO:0008585 49 33 0,000 0,08854222 0,10763589 ! positive regulation of cell development GO:0010720 54 33 0,000 0,08854222 0,10757903 ! lipid homeostasis GO:0055088 55 33 0,000 0,08854222 0,10752223 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,08854222 0,10746549 ! regulation of proteolysis GO:0030162 50 33 0,000 0,08854222 0,10740881 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,08854222 0,10735219 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,08854222 0,10729563 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,08854222 0,10723913 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,08854222 0,10718269 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,09110176 0,11022307 ! mRNA catabolic process GO:0006402 48 34 0,000 0,09110176 0,11016512 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,09110176 0,11010722 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,09110176 0,1100494 ! feeding behavior GO:0007631 45 34 0,000 0,09110176 0,10999163 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,09110176 0,10993392 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,09110176 0,10987627 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,09110176 0,10981868 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,09110176 0,10976116 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,09110176 0,10970369 ! neuron migration GO:0001764 46 34 0,000 0,09110176 0,10964628 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,09110176 0,10958894 ! female gamete generation GO:0007292 43 34 0,000 0,09110176 0,10953165 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,09110176 0,10947442 ! polyol metabolic process GO:0019751 44 34 0,000 0,09110176 0,10941726 ! aerobic respiration GO:0009060 47 34 0,000 0,09110176 0,10936015 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,09110176 0,1093031 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,09110176 0,10924612 ! embryonic organ development GO:0048568 45 34 0,000 0,09110176 0,10918919 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,09110176 0,10913232 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,09365426 0,1121316 ! Notch signaling pathway GO:0007219 56 35 0,000 0,09365426 0,11207326 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,09365426 0,11201498 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,09365426 0,11195676 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,09365426 0,1118986 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,09365426 0,1118405 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,09365426 0,11178246 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,09365426 0,11172448 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,09365426 0,11166656 ! glycogen metabolic process GO:0005977 48 35 0,000 0,09365426 0,1116087 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,09365426 0,11155091 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,09365426 0,11149317 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,09619974 0,11446425 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,09619974 0,11440507 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,09619974 0,11434594 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,09619974 0,11428688 ! organic ether metabolic process GO:0018904 46 36 0,000 0,09619974 0,11422788 ! tissue remodeling GO:0048771 62 36 0,000 0,09619974 0,11416893 ! neural tube development GO:0021915 50 36 0,000 0,09619974 0,11411005 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,09619974 0,11405124 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,09619974 0,11399248 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,09619974 0,11393378 ! glucan metabolic process GO:0044042 49 36 0,000 0,09619974 0,11387514 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,09873821 0,1168199 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,09873821 0,11675984 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,09873821 0,11669984 ! ion transmembrane transport GO:0034220 56 37 0,000 0,09873821 0,1166399 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,09873821 0,11658002 ! regulation of protein secretion GO:0050708 51 37 0,000 0,09873821 0,11652021 ! amino acid activation GO:0043038 52 37 0,000 0,09873821 0,11646045 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,09873821 0,11640076 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,1012697 0,11932393 ! gliogenesis GO:0042063 71 38 0,000 0,1012697 0,11926283 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,1012697 0,1192018 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,1012697 0,11914082 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,1012697 0,11907991 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,1012697 0,11901907 ! phagocytosis GO:0006909 60 38 0,000 0,1012697 0,11895828 ! mesenchymal cell development GO:0014031 64 38 0,000 0,1012697 0,11889756 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,10379422 0,12179934 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,10379422 0,12173723 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,10379422 0,12167519 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,10379422 0,1216132 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,10379422 0,12155128 ! male sex differentiation GO:0046661 53 39 0,000 0,10379422 0,12148942 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,10379422 0,12142763 ! chromatin remodeling GO:0006338 68 39 0,000 0,10379422 0,12136589 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,10379422 0,12130422 ! JNK cascade GO:0007254 54 39 0,000 0,10379422 0,12124262 ! developmental growth GO:0048589 62 39 0,000 0,10379422 0,12118107 ! cell growth GO:0016049 61 39 0,000 0,10379422 0,12111959 ! synapse organization GO:0050808 55 39 0,000 0,10379422 0,12105817 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,1063118 0,12393165 ! response to calcium ion GO:0051592 58 40 0,000 0,1063118 0,12386887 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,1063118 0,12380615 ! regulation of tube size GO:0035150 60 40 0,000 0,1063118 0,12374349 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,1063118 0,1236809 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,1063118 0,12361837 ! peptide metabolic process GO:0006518 56 40 0,000 0,1063118 0,12355591 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,1063118 0,1234935 ! inner ear development GO:0048839 57 40 0,000 0,1063118 0,12343117 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,1063118 0,12336889 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,1063118 0,12330668 ! double-strand break repair GO:0006302 67 40 0,000 0,1063118 0,12324453 ! B cell differentiation GO:0030183 62 40 0,000 0,1063118 0,12318244 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,1063118 0,12312041 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,1063118 0,12305845 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,10882245 0,12590122 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,10882245 0,12583792 ! glucose transport GO:0015758 52 41 0,000 0,10882245 0,12577469 ! striated muscle contraction GO:0006941 62 41 0,000 0,10882245 0,12571152 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,10882245 0,12564841 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,10882245 0,12558536 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,10882245 0,12552238 ! biopolymer methylation GO:0043414 62 41 0,000 0,10882245 0,12545946 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,10882245 0,12539661 ! mitochondrial transport GO:0006839 60 42 0,000 0,11132619 0,12821744 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,11132619 0,12815327 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,11132619 0,12808916 ! cellular component disassembly GO:0022411 64 42 0,000 0,11132619 0,12802511 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,11132619 0,12796113 ! hexose transport GO:0008645 54 42 0,000 0,11132619 0,12789722 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,11132619 0,12783336 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,11132619 0,12776957 ! excretion GO:0007588 63 42 0,000 0,11132619 0,12770585 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,11132619 0,12764219 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,11132619 0,12757859 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,11132619 0,12751505 ! positive regulation of binding GO:0051099 59 43 0,000 0,11382303 0,13031009 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,11382303 0,13024526 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,11382303 0,1301805 ! activation of caspase activity GO:0006919 65 43 0,000 0,11382303 0,13011579 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,11382303 0,13005116 ! tRNA processing GO:0008033 49 43 0,000 0,11382303 0,12998658 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,11382303 0,12992207 ! vesicle organization GO:0016050 79 43 0,000 0,11382303 0,12985763 ! response to insulin stimulus GO:0032868 63 43 0,000 0,11382303 0,12979325 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,11382303 0,12972893 ! methylation GO:0032259 64 43 0,000 0,11382303 0,12966467 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,11631301 0,1324356 ! glycolysis GO:0006096 53 44 0,000 0,11631301 0,13237007 ! regulation of ion transport GO:0043269 57 44 0,000 0,11631301 0,13230461 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,11631301 0,13223921 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,11631301 0,13217387 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,11631301 0,1321086 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,11631301 0,1320434 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,11631301 0,13197825 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,11631301 0,13191318 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,11631301 0,13184816 ! positive regulation of cell cycle GO:0045787 77 45 0,000 0,11879613 0,1345966 ! RNA catabolic process GO:0006401 64 45 0,000 0,11879613 0,13453033 ! positive regulation of defense response GO:0031349 59 45 0,000 0,11879613 0,13446412 ! regulation of translational initiation GO:0006446 64 45 0,000 0,11879613 0,13439798 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,11879613 0,13433191 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,11879613 0,1342659 ! cell recognition GO:0008037 58 45 0,000 0,11879613 0,13419995 ! protein amino acid autophosphorylation GO:0046777 80 45 0,000 0,11879613 0,13413407 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,12127241 0,13686288 ! cell redox homeostasis GO:0045454 63 46 0,000 0,12127241 0,13679576 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,12127241 0,1367287 ! regulation of ossification GO:0030278 71 46 0,000 0,12127241 0,13666171 ! histone modification GO:0016570 68 46 0,000 0,12127241 0,13659479 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,12127241 0,13652793 ! response to UV GO:0009411 75 46 0,000 0,12127241 0,13646113 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,12374188 0,1391718 ! viral infectious cycle GO:0019058 71 47 0,000 0,12374188 0,13910378 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,12374188 0,13903582 ! endocrine system development GO:0035270 83 47 0,000 0,12374188 0,13896794 ! covalent chromatin modification GO:0016569 75 47 0,000 0,12374188 0,13890011 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,12374188 0,13883236 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,12374188 0,13876467 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,12374188 0,13869704 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,12374188 0,13862948 ! chloride transport GO:0006821 67 48 0,000 0,12620455 0,14131961 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,12620455 0,14125084 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,12620455 0,14118214 ! response to temperature stimulus GO:0009266 62 48 0,000 0,12620455 0,1411135 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,12620455 0,14104493 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,12620455 0,14097643 ! heart morphogenesis GO:0003007 65 48 0,000 0,12620455 0,140908 ! regulation of DNA replication GO:0006275 75 48 0,000 0,12620455 0,14083963 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,12620455 0,14077132 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,12620455 0,14070309 ! regulation of endocytosis GO:0030100 63 48 0,000 0,12620455 0,14063492 ! nuclear export GO:0051168 69 48 0,000 0,12620455 0,14056681 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,12620455 0,14049878 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,12866044 0,14316353 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,12866044 0,1430943 ! sensory perception of smell GO:0007608 61 49 0,000 0,12866044 0,14302514 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,12866044 0,14295605 ! RNA elongation GO:0006354 62 49 0,000 0,12866044 0,14288702 ! germ cell development GO:0007281 68 49 0,000 0,12866044 0,14281806 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,12866044 0,14274916 ! cartilage development GO:0051216 70 49 0,000 0,12866044 0,14268034 ! regulation of actin filament length GO:0030832 72 50 0,000 0,13110957 0,14532627 ! ear development GO:0043583 72 50 0,000 0,13110957 0,14525627 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,13110957 0,14518633 ! lipid modification GO:0030258 73 50 0,000 0,13110957 0,14511646 ! positive regulation of growth GO:0045927 67 50 0,000 0,13110957 0,14504666 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,13110957 0,14497693 ! proton transport GO:0015992 75 50 0,000 0,13110957 0,14490726 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,13110957 0,14483766 ! positive regulation of secretion GO:0051047 71 51 0,000 0,13355195 0,14746495 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,13355195 0,14739419 ! hydrogen transport GO:0006818 77 51 0,000 0,13355195 0,1473235 ! positive regulation of cell migration GO:0030335 92 51 0,000 0,13355195 0,14725287 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,13355195 0,14718232 ! transition metal ion transport GO:0000041 74 52 0,000 0,13598761 0,14979478 ! regulation of cellular component size GO:0032535 74 52 0,000 0,13598761 0,14972308 ! aging GO:0007568 79 52 0,000 0,13598761 0,14965144 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,13598761 0,14957987 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,13598761 0,14950837 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,13841656 0,15210611 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,13841656 0,15203347 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,13841656 0,1519609 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,13841656 0,1518884 ! kidney development GO:0001822 90 53 0,000 0,13841656 0,15181597 ! single fertilization GO:0007338 59 53 0,000 0,13841656 0,15174361 ! cell projection assembly GO:0030031 76 53 0,000 0,13841656 0,15167132 ! amino acid transport GO:0006865 84 54 0,000 0,14083882 0,15425204 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,14083882 0,15417863 ! regulation of mitosis GO:0007088 84 54 0,000 0,14083882 0,15410528 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,14083882 0,154032 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,14083882 0,15395879 ! DNA catabolic process GO:0006308 67 54 0,000 0,14083882 0,15388565 ! detection of external stimulus GO:0009581 66 54 0,000 0,14083882 0,15381258 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,14083882 0,15373958 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,14083882 0,15366665 ! exocytosis GO:0006887 74 55 0,000 0,14325441 0,15622814 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,14325441 0,1561541 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,14325441 0,15608013 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,14566335 0,15862959 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,14566335 0,15855452 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,14566335 0,15847952 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,14566335 0,15840459 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,14806565 0,16094092 ! carbohydrate transport GO:0008643 74 57 0,000 0,14806565 0,1608649 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,14806565 0,16078895 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,14806565 0,16071307 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,14806565 0,16063726 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,14806565 0,16056153 ! camera-type eye development GO:0043010 88 57 0,000 0,14806565 0,16048586 ! secondary metabolic process GO:0019748 84 57 0,000 0,14806565 0,16041027 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,14806565 0,16033474 ! gonad development GO:0008406 79 57 0,000 0,14806565 0,16025929 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,15046133 0,16277567 ! viral reproductive process GO:0022415 87 58 0,000 0,15046133 0,16269914 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,15046133 0,16262268 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,15046133 0,1625463 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,15046133 0,16246998 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,15285042 0,16497229 ! activation of MAPK activity GO:0000187 84 59 0,000 0,15285042 0,16489492 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,15523292 0,16738664 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,15523292 0,16730821 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,15523292 0,16722984 ! regulation of heart contraction GO:0008016 91 60 0,000 0,15523292 0,16715155 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,15523292 0,16707333 ! fertilization GO:0009566 68 60 0,000 0,15523292 0,16699519 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,15523292 0,16691712 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,15760886 0,1693927 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,15760886 0,16931358 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,15760886 0,16923453 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,15760886 0,16915556 ! extracellular matrix organization GO:0030198 103 61 0,000 0,15760886 0,16907667 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,15760886 0,16899784 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,15760886 0,16891909 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,15760886 0,16884041 ! amine catabolic process GO:0009310 90 62 0,000 0,15997825 0,17129887 ! neurotransmitter transport GO:0006836 81 62 0,000 0,15997825 0,17121916 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,15997825 0,17113952 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,15997825 0,17105996 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,15997825 0,17098047 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,15997825 0,17090105 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,16234111 0,17334473 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,16234111 0,17326429 ! viral reproduction GO:0016032 92 63 0,000 0,16234111 0,17318393 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,16469746 0,17561621 ! negative regulation of cell size GO:0045792 108 64 0,000 0,16469746 0,17553483 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,16469746 0,17545353 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,16469746 0,1753723 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,16469746 0,17529114 ! hexose catabolic process GO:0019320 82 64 0,000 0,16469746 0,17521007 ! adaptive immune response GO:0002250 94 64 0,000 0,16469746 0,17512906 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 0,000 0,16704732 0,17754567 ! B cell activation GO:0042113 104 65 0,000 0,16704732 0,17746367 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,16704732 0,17738173 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,16704732 0,17729988 ! defense response to bacterium GO:0042742 73 65 0,000 0,16704732 0,1772181 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,16704732 0,17713639 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,16704732 0,17705476 ! activation of immune response GO:0002253 83 65 0,000 0,16704732 0,17697321 ! protein oligomerization GO:0051259 100 65 0,000 0,16704732 0,17689173 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,1693907 0,17929066 ! antigen processing and presentation GO:0019882 96 66 0,000 0,1693907 0,17920819 ! axon guidance GO:0007411 99 66 0,000 0,1693907 0,1791258 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,1693907 0,17904348 ! regulation of immune effector process GO:0002697 101 66 0,000 0,1693907 0,17896124 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,17172762 0,18134689 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,17172762 0,18126367 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,17172762 0,18118052 ! acute inflammatory response GO:0002526 92 68 0,000 0,17405811 0,18355509 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,17405811 0,18347097 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,17405811 0,18338692 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,17405811 0,18330295 ! rhythmic process GO:0048511 105 68 0,000 0,17405811 0,18321906 ! inorganic anion transport GO:0015698 93 68 0,000 0,17405811 0,18313525 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,17638217 0,18549565 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,17638217 0,18541087 ! response to drug GO:0042493 108 69 0,000 0,17638217 0,18532617 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,17638217 0,18524154 ! response to metal ion GO:0010038 103 70 0,000 0,17869982 0,18758995 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,17869982 0,18750437 ! humoral immune response GO:0006959 86 70 0,000 0,17869982 0,18741887 ! eye development GO:0001654 111 70 0,000 0,17869982 0,18733345 ! amine transport GO:0015837 101 70 0,000 0,17869982 0,1872481 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,17869982 0,18716283 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,17869982 0,18707764 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,18101108 0,18941105 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,18101108 0,18932491 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,18101108 0,18923886 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,18101108 0,18915288 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,18101108 0,18906698 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,18331597 0,19138753 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,18331597 0,1913007 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 0,000 0,18331597 0,19121394 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,18331597 0,19112726 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,18331597 0,19104066 ! regulation of blood pressure GO:0008217 107 73 0,000 0,18561451 0,19334845 ! mitochondrion organization GO:0007005 104 73 0,000 0,18561451 0,19326092 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,18561451 0,19317347 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,18561451 0,1930861 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,18790671 0,1953822 ! response to oxygen levels GO:0070482 137 74 0,000 0,18790671 0,19529391 ! digestion GO:0007586 97 74 0,000 0,18790671 0,1952057 ! protein import into nucleus GO:0006606 118 74 0,000 0,18790671 0,19511757 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,18790671 0,19502952 ! response to inorganic substance GO:0010035 115 75 0,000 0,19019258 0,19731301 ! negative regulation of growth GO:0045926 123 75 0,000 0,19019258 0,19722405 ! response to nutrient GO:0007584 104 75 0,000 0,19019258 0,19713517 ! regulation of ligase activity GO:0051340 114 75 0,000 0,19019258 0,19704637 ! nuclear import GO:0051170 121 75 0,000 0,19019258 0,19695765 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,19019258 0,19686901 ! amine biosynthetic process GO:0009309 97 76 0,000 0,19247216 0,19913899 ! tRNA metabolic process GO:0006399 95 76 0,000 0,19247216 0,19904945 ! response to unfolded protein GO:0006986 99 76 0,000 0,19247216 0,19895999 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,19474545 0,20121947 ! sex differentiation GO:0007548 105 77 0,000 0,19474545 0,20112911 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,19474545 0,20103884 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,19474545 0,20094865 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,19474545 0,20085853 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,19701247 0,20310564 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,19701247 0,20301464 ! cellular respiration GO:0045333 107 79 0,000 0,19927324 0,20525232 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,19927324 0,20516045 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,19927324 0,20506865 ! chromatin assembly GO:0031497 102 80 0,000 0,20152777 0,207296 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,20152777 0,20720334 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,20152777 0,20711075 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,20152777 0,20701825 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,20152777 0,20692583 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,20377608 0,209141 ! response to protein stimulus GO:0051789 111 81 0,000 0,20377608 0,20904772 ! vitamin metabolic process GO:0006766 103 81 0,000 0,20377608 0,20895452 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,20377608 0,2088614 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,20601819 0,21106541 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,20601819 0,21097143 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,20825412 0,21316621 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,20825412 0,21307138 ! regulation of defense response GO:0031347 117 84 0,000 0,21048387 0,21525696 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,21048387 0,21516129 ! sterol metabolic process GO:0016125 120 84 0,000 0,21048387 0,21506571 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,21270748 0,21724121 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,21270748 0,21714479 ! rRNA metabolic process GO:0016072 107 85 0,000 0,21270748 0,21704845 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 0,000 0,21270748 0,2169522 ! transcription initiation GO:0006352 118 85 0,000 0,21270748 0,21685603 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,21270748 0,21675995 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,21270748 0,21666395 ! cell cycle arrest GO:0007050 150 86 0,000 0,21492495 0,21882576 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,21492495 0,21872893 ! nucleosome organization GO:0034728 114 87 0,000 0,2171363 0,22088169 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,2171363 0,22078404 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,2171363 0,22068648 ! female pregnancy GO:0007565 130 87 0,000 0,2171363 0,220589 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,2171363 0,22049161 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,21934155 0,22263264 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,21934155 0,22253444 ! interphase GO:0051325 159 88 0,000 0,21934155 0,22243632 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,21934155 0,22233828 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,21934155 0,22224034 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,22154072 0,22436973 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,22154072 0,22427097 ! regulation of T cell activation GO:0050863 128 89 0,000 0,22154072 0,2241723 ! ATP metabolic process GO:0046034 137 91 0,000 0,22592085 0,22850394 ! response to virus GO:0009615 122 91 0,000 0,22592085 0,2284035 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,22810186 0,23050715 ! positive regulation of immune response GO:0050778 121 92 0,000 0,22810186 0,23040592 ! DNA recombination GO:0006310 146 92 0,000 0,22810186 0,23030477 ! sulfur metabolic process GO:0006790 118 92 0,000 0,22810186 0,23020372 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,23027685 0,23229682 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,23027685 0,23219498 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,23027685 0,23209323 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,23027685 0,23199157 ! electron transport chain GO:0022900 123 94 0,000 0,23244583 0,23407417 ! response to oxidative stress GO:0006979 141 94 0,000 0,23244583 0,23397173 ! carboxylic acid transport GO:0046942 147 95 0,000 0,23460882 0,23604562 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,23676585 0,23811169 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,23676585 0,23800763 ! protein maturation GO:0051604 129 96 0,000 0,23676585 0,23790365 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,23891691 0,23996022 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,24320125 0,24415665 ! extracellular structure organization GO:0043062 156 99 0,000 0,24320125 0,24405012 ! protein import GO:0017038 156 99 0,000 0,24320125 0,24394369 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,24320125 0,24383735 ! regulation of translation GO:0006417 151 100 0,000 0,24533455 0,24586905 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,24533455 0,24576196 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,24533455 0,24565497 ! divalent metal ion transport GO:0070838 171 100 0,000 0,24533455 0,24554807 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,24533455 0,24544126 ! protein localization in organelle GO:0033365 161 100 0,000 0,24533455 0,24533455