pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6884-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glutamate signaling pathway GO:0007215 41 22 3,000 2,789E-07 6,711E-04 ! dopamine receptor signaling pathway GO:0007212 28 12 2,000 3,477E-06 4,183E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 5,731E-06 4,597E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 2,000 7,151E-06 4,301E-03 ! regulation of postsynaptic membrane potential GO:0060078 32 19 2,000 1,512E-05 7,275E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 1,512E-05 6,062E-03 ! visual learning GO:0008542 36 19 2,000 1,512E-05 5,196E-03 ! actin filament organization GO:0007015 148 66 3,000 2,524E-05 7,59E-03 ! visual behavior GO:0007632 42 23 2,000 2,743E-05 7,332E-03 ! response to ethanol GO:0045471 46 23 2,000 2,743E-05 6,599E-03 ! membrane depolarization GO:0051899 39 24 2,000 3,129E-05 6,844E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 6,42E-05 0,01287197 GO:0032414|positive regulation of ion transmembrane transporter activity, ! forebrain neuron development GO:0021884 13 5 1,000 6,42E-05 0,01188182 ! early endosome to late endosome transport GO:0045022 12 5 1,000 6,42E-05 0,01103312 ! metaphase GO:0051323 8 5 1,000 6,42E-05 0,01029758 ! regulation of sensory perception GO:0051931 7 5 1,000 6,42E-05 9,654E-03 GO:0051930|regulation of sensory perception of pain, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 1,000 6,42E-05 9,086E-03 ! neuron remodeling GO:0016322 15 6 1,000 9,614E-05 0,01285061 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 9,614E-05 0,01217427 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! establishment of spindle localization GO:0051293 12 6 1,000 9,614E-05 0,01156555 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 1,000 9,614E-05 0,01101481 ! purine base biosynthetic process GO:0009113 17 6 1,000 9,614E-05 0,01051414 ! negative regulation of B cell activation GO:0050869 13 6 1,000 9,614E-05 0,010057 ! regulation of membrane potential GO:0042391 164 93 3,000 9,703E-05 9,728E-03 ! prostate gland development GO:0030850 13 7 1,000 1,344E-04 0,01293193 ! forebrain neuron differentiation GO:0021879 16 7 1,000 1,344E-04 0,01243455 ! learning GO:0007612 77 39 2,000 1,374E-04 0,01224651 ! generation of neurons in the forebrain GO:0021872 18 8 1,000 1,789E-04 0,01536961 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,789E-04 0,01483963 ! receptor clustering GO:0043113 18 9 1,000 2,296E-04 0,01841295 ! negative regulation of lymphocyte differentiation GO:0045620 19 9 1,000 2,296E-04 0,01781898 ! purine base metabolic process GO:0006144 21 9 1,000 2,296E-04 0,01726214 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,72E-04 0,01983206 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 1,000 2,865E-04 0,02027472 GO:0007520|myoblast fusion, ! nucleobase biosynthetic process GO:0046112 24 10 1,000 2,865E-04 0,01969545 ! epithelial cell development GO:0002064 20 10 1,000 2,865E-04 0,01914835 ! regulation of B cell differentiation GO:0045577 19 10 1,000 2,865E-04 0,01863083 ! establishment of cell polarity GO:0030010 16 10 1,000 2,865E-04 0,01814054 ! cell maturation GO:0048469 100 53 2,000 3,433E-04 0,02118077 ! syncytium formation GO:0006949 18 11 1,000 3,496E-04 0,02102827 ! negative regulation of cell motion GO:0051271 134 55 2,000 3,831E-04 0,02248076 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 4,188E-04 0,02399247 ! focal adhesion formation GO:0048041 35 12 1,000 4,188E-04 0,02343451 ! membrane protein proteolysis GO:0033619 25 12 1,000 4,188E-04 0,0229019 GO:0006509|membrane protein ectodomain proteolysis, ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 4,942E-04 0,02642056 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 4,942E-04 0,0258462 ! myotube differentiation GO:0014902 25 14 1,000 5,756E-04 0,02946343 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 2,000 6,548E-04 0,0328243 ! developmental maturation GO:0021700 116 66 2,000 6,548E-04 0,03215442 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 6,63E-04 0,03190355 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! cAMP-mediated signaling GO:0019933 120 69 2,000 7,457E-04 0,03517822 ! startle response GO:0001964 28 16 1,000 7,565E-04 0,03500078 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 7,565E-04 0,03434038 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! embryonic digit morphogenesis GO:0042733 34 16 1,000 7,565E-04 0,03370445 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 7,565E-04 0,03309164 ! signal complex assembly GO:0007172 41 17 1,000 8,559E-04 0,03677315 ! endothelial cell migration GO:0043542 28 17 1,000 8,559E-04 0,03612801 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 8,559E-04 0,03550511 ! nucleobase metabolic process GO:0009112 37 17 1,000 8,559E-04 0,03490333 ! learning or memory GO:0007611 147 73 2,000 8,787E-04 0,03523631 ! neuron maturation GO:0042551 42 18 1,000 9,613E-04 0,03791595 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 9,613E-04 0,0373044 ! glutamine metabolic process GO:0006541 29 18 1,000 9,613E-04 0,03671226 ! cell-substrate junction assembly GO:0007044 54 18 1,000 9,613E-04 0,03613864 ! pigmentation during development GO:0048066 41 19 1,000 1,073E-03 0,03970302 ! plasma membrane fusion GO:0045026 28 19 1,000 1,073E-03 0,03910146 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 1,146E-03 0,04115261 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,19E-03 0,04209844 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,19E-03 0,04148832 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 1,19E-03 0,04089563 ! actin filament-based movement GO:0030048 43 20 1,000 1,19E-03 0,04031964 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 1,231E-03 0,04112699 ! regulation of cyclase activity GO:0031279 159 82 2,000 1,231E-03 0,04056361 ! regulation of lyase activity GO:0051339 160 83 2,000 1,275E-03 0,04144011 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 1,319E-03 0,04232441 ! central nervous system neuron development GO:0021954 46 22 1,000 1,442E-03 0,04564375 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,442E-03 0,04505098 ! protein stabilization GO:0050821 39 22 1,000 1,442E-03 0,0444734 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 1,46E-03 0,04445357 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 1,576E-03 0,04741268 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,576E-03 0,04682734 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 1,609E-03 0,04720797 ! regulation of transmembrane transport GO:0034762 38 24 1,000 1,717E-03 0,04977097 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 1,717E-03 0,04917845 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 1,767E-03 0,05002934 ! receptor metabolic process GO:0043112 46 25 1,000 1,863E-03 0,05212537 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 1,863E-03 0,05152623 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,015E-03 0,05509452 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 2,000 2,113E-03 0,05712313 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 1,000 2,173E-03 0,05808365 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,173E-03 0,05744536 ! cell junction assembly GO:0034329 78 30 1,000 2,679E-03 0,07007064 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,679E-03 0,06931719 ! regulation of B cell activation GO:0050864 50 30 1,000 2,679E-03 0,06857978 ! mesoderm formation GO:0001707 69 31 1,000 2,859E-03 0,07241792 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 2,859E-03 0,07166357 GO:0043433|negative regulation of transcription factor activity, ! spindle organization GO:0007051 46 32 1,000 3,045E-03 0,07552815 ! pigment biosynthetic process GO:0046148 66 32 1,000 3,045E-03 0,07475746 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,045E-03 0,07400233 ! post-embryonic development GO:0009791 69 33 1,000 3,236E-03 0,07786014 ! formation of primary germ layer GO:0001704 72 33 1,000 3,236E-03 0,07708925 ! cell fate specification GO:0001708 52 33 1,000 3,236E-03 0,07633347 ! adult locomotory behavior GO:0008344 59 33 1,000 3,236E-03 0,07559237 ! negative regulation of protein transport GO:0051224 69 33 1,000 3,236E-03 0,07486552 ! positive regulation of endocytosis GO:0045807 50 34 1,000 3,433E-03 0,07865698 ! mesoderm morphogenesis GO:0048332 76 34 1,000 3,433E-03 0,07791494 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 3,842E-03 0,08639445 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 3,842E-03 0,0855945 ! maintenance of protein location in cell GO:0032507 86 36 1,000 3,842E-03 0,08480923 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,842E-03 0,08403824 ! meiosis I GO:0007127 65 37 1,000 4,055E-03 0,0878948 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 4,055E-03 0,08711003 ! negative regulation of DNA binding GO:0043392 68 37 1,000 4,055E-03 0,08633914 ! regulation of protein stability GO:0031647 73 37 1,000 4,055E-03 0,08558178 ! pigment metabolic process GO:0042440 80 37 1,000 4,055E-03 0,08483759 ! carbohydrate homeostasis GO:0033500 53 38 1,000 4,273E-03 0,08863235 GO:0042593|glucose homeostasis, ! negative regulation of binding GO:0051100 72 40 1,000 4,726E-03 0,09717848 ! maintenance of protein location GO:0045185 91 40 1,000 4,726E-03 0,09635494 ! cytokinesis GO:0000910 72 40 1,000 4,726E-03 0,09554523 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 4,96E-03 0,09944373 ! hormone-mediated signaling GO:0009755 74 41 1,000 4,96E-03 0,09862188 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 5,199E-03 0,10253488 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 5,199E-03 0,10170127 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 5,199E-03 0,1008811 ! epithelial cell differentiation GO:0030855 79 43 1,000 5,444E-03 0,10478274 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 5,444E-03 0,10395113 ! activation of adenylate cyclase activity GO:0007190 91 44 1,000 5,694E-03 0,10786567 ! maintenance of location in cell GO:0051651 97 44 1,000 5,694E-03 0,10702297 ! leukocyte migration GO:0050900 68 45 1,000 5,949E-03 0,11094947 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 5,949E-03 0,11009602 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 6,209E-03 0,11403362 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 6,209E-03 0,11316973 ! pigmentation GO:0043473 100 46 1,000 6,209E-03 0,11231883 ! positive regulation of protein transport GO:0051222 72 46 1,000 6,209E-03 0,11148063 ! endosome transport GO:0016197 108 47 1,000 6,474E-03 0,11538251 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 6,474E-03 0,11453411 ! positive regulation of lyase activity GO:0051349 104 48 1,000 6,744E-03 0,11844615 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,744E-03 0,11758785 ! regulation of action potential GO:0001508 95 49 1,000 7,02E-03 0,12150928 ! neuromuscular process GO:0050905 99 50 1,000 7,3E-03 0,12546124 ! negative regulation of immune system process GO:0002683 95 50 1,000 7,3E-03 0,12457145 ! regulation of cell shape GO:0008360 125 51 1,000 7,586E-03 0,12853107 ! membrane fusion GO:0006944 110 52 1,000 7,876E-03 0,13251916 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 7,876E-03 0,13159889 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 8,172E-03 0,13559305 ! activation of phospholipase C activity GO:0007202 103 54 1,000 8,472E-03 0,13961374 GO:0010863|positive regulation of phospholipase C activity, ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 8,472E-03 0,13866399 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 8,777E-03 0,14268931 ! regulation of protein catabolic process GO:0042176 116 55 1,000 8,777E-03 0,14173166 ! gastrulation GO:0007369 112 55 1,000 8,777E-03 0,14078678 ! skeletal muscle fiber development GO:0048741 111 56 1,000 9,087E-03 0,14479578 ! muscle fiber development GO:0048747 112 57 1,000 9,402E-03 0,14882881 ! regulation of phospholipase activity GO:0010517 106 57 1,000 9,402E-03 0,14785607 ! regulation of intracellular transport GO:0032386 101 57 1,000 9,402E-03 0,14689597 ! maintenance of location GO:0051235 118 57 1,000 9,402E-03 0,14594825 ! regulation of endocytosis GO:0030100 91 58 1,000 9,722E-03 0,14994489 ! adult behavior GO:0030534 99 58 1,000 9,722E-03 0,14898983 ! positive regulation of lipase activity GO:0060193 108 58 1,000 9,722E-03 0,14804685 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,0100467 0,15202749 ! establishment of organelle localization GO:0051656 109 59 1,000 0,0100467 0,15107732 ! mesoderm development GO:0007498 119 61 1,000 0,01071018 0,16005401 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,01139254 0,16920034 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,01174074 0,17330195 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,01209358 0,17742167 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 1,000 0,01209358 0,17634639 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01271912 0,18435059 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01271912 0,1832467 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01271912 0,18215594 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01271912 0,1810781 ! neuron fate determination GO:0048664 7 5 0,000 0,01271912 0,18001293 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01271912 0,17896022 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01271912 0,17791976 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01271912 0,17689132 ! polyol transport GO:0015791 12 5 0,000 0,01271912 0,1758747 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01271912 0,1748697 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01271912 0,17387613 ! response to superoxide GO:0000303 10 5 0,000 0,01271912 0,17289378 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01271912 0,17192246 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01271912 0,170962 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01271912 0,17001221 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01271912 0,16907292 ! female meiosis GO:0007143 7 5 0,000 0,01271912 0,16814395 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01271912 0,16722513 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01271912 0,16631629 ! cobalt ion transport GO:0006824 11 5 0,000 0,01271912 0,16541729 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01271912 0,16452795 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01271912 0,16364812 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01271912 0,16277765 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01271912 0,16191639 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01271912 0,1610642 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01271912 0,16022093 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01271912 0,15938645 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01271912 0,15856061 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01271912 0,15774329 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01271912 0,15693435 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01271912 0,15613366 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01271912 0,15534111 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01271912 0,15455656 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01271912 0,15377989 ! negative chemotaxis GO:0050919 14 5 0,000 0,01271912 0,15301099 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01271912 0,15224974 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01271912 0,15149603 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01271912 0,15074974 ! behavioral response to pain GO:0048266 9 5 0,000 0,01271912 0,15001078 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01271912 0,14927902 ! Notch receptor processing GO:0007220 8 5 0,000 0,01271912 0,14855436 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01271912 0,14783671 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01271912 0,14712595 ! micturition GO:0060073 9 5 0,000 0,01271912 0,146422 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01271912 0,14572475 ! copulation GO:0007620 9 5 0,000 0,01271912 0,14503411 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01271912 0,14434999 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01271912 0,14367229 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01271912 0,14300093 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01271912 0,14233581 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01271912 0,14167684 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01271912 0,14102395 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01271912 0,14037706 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01271912 0,13973606 ! grooming behavior GO:0007625 6 5 0,000 0,01271912 0,1391009 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01271912 0,13847148 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01271912 0,13784774 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01271912 0,13722959 ! response to protozoan GO:0001562 10 5 0,000 0,01271912 0,13661696 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01271912 0,13600977 ! lymph vessel development GO:0001945 10 5 0,000 0,01271912 0,13540796 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01271912 0,13481145 ! endochondral ossification GO:0001958 16 5 0,000 0,01271912 0,13422017 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01271912 0,13363405 ! parathyroid gland development GO:0060017 13 5 0,000 0,01271912 0,13305304 ! anagen GO:0042640 6 5 0,000 0,01271912 0,13247705 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01271912 0,13190603 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01271912 0,13133991 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01271912 0,13077862 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01271912 0,13022212 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01271912 0,12967033 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01271912 0,1291232 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01271912 0,12858066 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01271912 0,12804267 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01271912 0,12750916 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01271912 0,12698008 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01271912 0,12645536 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01271912 0,12593497 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01271912 0,12541885 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01271912 0,12490693 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01271912 0,12439918 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01271912 0,12389554 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01271912 0,12339596 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01271912 0,12290039 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01271912 0,12240879 ! histidine catabolic process GO:0006548 6 5 0,000 0,01271912 0,12192111 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01271912 0,12143729 ! microvillus organization GO:0032528 7 5 0,000 0,01271912 0,12095731 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01271912 0,1204811 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01271912 0,12000862 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01271912 0,11953984 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01271912 0,1190747 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01271912 0,11861317 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01271912 0,11815521 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01271912 0,11770076 ! polyol catabolic process GO:0046174 7 5 0,000 0,01271912 0,1172498 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01271912 0,11680228 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01271912 0,11635817 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01271912 0,11591742 ! muscle cell migration GO:0014812 8 5 0,000 0,01271912 0,11547999 ! mitochondrial fission GO:0000266 8 5 0,000 0,01271912 0,11504586 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01271912 0,11461497 ! mRNA transcription GO:0009299 9 5 0,000 0,01271912 0,11418731 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01271912 0,11376282 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01271912 0,11334147 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01271912 0,11292324 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01271912 0,11250808 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01271912 0,11209596 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01271912 0,11168685 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01271912 0,11128072 ! response to food GO:0032094 6 5 0,000 0,01271912 0,11087753 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01271912 0,11047725 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01271912 0,11007985 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01271912 0,1096853 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01271912 0,10929356 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01271912 0,10890462 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01271912 0,10851843 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01271912 0,10813498 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01271912 0,10775422 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01271912 0,10737613 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01271912 0,10700069 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01271912 0,10662787 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01271912 0,10625763 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01271912 0,10588996 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01271912 0,10552482 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01271912 0,10516219 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01271912 0,10480205 ! basic amino acid transport GO:0015802 11 5 0,000 0,01271912 0,10444436 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01271912 0,10408911 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01271912 0,10373627 ! depyrimidination GO:0045008 10 5 0,000 0,01271912 0,1033858 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01271912 0,1030377 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01271912 0,10269194 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01271912 0,10234849 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01271912 0,10200733 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01271912 0,10166843 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01271912 0,10133178 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01271912 0,10099735 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01271912 0,10066513 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01271912 0,10033508 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01271912 0,10000718 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01271912 0,09968143 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01271912 0,09935779 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01271912 0,09903624 ! response to arsenic GO:0046685 10 5 0,000 0,01271912 0,09871677 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01271912 0,09839935 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01271912 0,09808397 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01271912 0,0977706 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01271912 0,09745923 ! response to cadmium ion GO:0046686 7 5 0,000 0,01271912 0,09714984 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01271912 0,0968424 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01271912 0,0965369 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01271912 0,09623333 ! decidualization GO:0046697 11 5 0,000 0,01271912 0,09593166 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01271912 0,09563187 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01271912 0,09533395 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01271912 0,09503788 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01271912 0,09474365 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01271912 0,09445123 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01271912 0,09416061 ! neural tube patterning GO:0021532 7 5 0,000 0,01271912 0,09387177 ! embryonic cleavage GO:0040016 6 5 0,000 0,01271912 0,0935847 ! peroxisome fission GO:0016559 5 5 0,000 0,01271912 0,09329938 ! histone demethylation GO:0016577 10 5 0,000 0,01271912 0,0930158 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01271912 0,09273393 ! mitotic recombination GO:0006312 9 5 0,000 0,01271912 0,09245377 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01271912 0,0921753 ! metaphase plate congression GO:0051310 7 5 0,000 0,01271912 0,09189849 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01271912 0,09162335 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01271912 0,09134985 ! enteric nervous system development GO:0048484 8 5 0,000 0,01271912 0,09107797 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01271912 0,09080771 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01271912 0,09053905 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01271912 0,09027197 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01271912 0,09000647 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01271912 0,08974252 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01271912 0,08948011 ! plasminogen activation GO:0031639 5 5 0,000 0,01271912 0,08921924 ! B cell homeostasis GO:0001782 13 5 0,000 0,01271912 0,08895988 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01271912 0,08870202 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01271912 0,08844566 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01271912 0,08819077 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01271912 0,08793735 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01271912 0,08768538 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01271912 0,08743485 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01271912 0,08718575 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01271912 0,08693806 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01271912 0,08669178 ! response to redox state GO:0051775 5 5 0,000 0,01271912 0,08644689 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01271912 0,08620338 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01271912 0,08596123 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01271912 0,08572044 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01271912 0,085481 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01271912 0,08524289 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01271912 0,08500611 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01271912 0,08477063 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01271912 0,08453646 ! striatum development GO:0021756 9 5 0,000 0,01271912 0,08430358 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01271912 0,08407197 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01271912 0,08384164 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01271912 0,08361256 ! glial cell migration GO:0008347 11 5 0,000 0,01271912 0,08338474 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01271912 0,08315815 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01271912 0,08293279 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01271912 0,08270864 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01271912 0,08248571 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01271912 0,08226397 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01271912 0,08204343 ! neuroprotection GO:0043526 6 5 0,000 0,01271912 0,08182406 ! neural plate development GO:0001840 8 5 0,000 0,01271912 0,08160586 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01271912 0,08138882 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01271912 0,08117294 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01271912 0,0809582 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01271912 0,08074459 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01271912 0,0805321 GO:0051497|negative regulation of stress fiber formation, ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01271912 0,08032073 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01271912 0,08011047 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01271912 0,0799013 ! spindle assembly GO:0051225 6 5 0,000 0,01271912 0,07969322 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01271912 0,07948623 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01271912 0,07928031 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01271912 0,07907545 ! drug metabolic process GO:0017144 6 5 0,000 0,01271912 0,07887164 ! stem cell division GO:0017145 11 5 0,000 0,01271912 0,07866889 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01271912 0,07846717 ! organ regeneration GO:0031100 7 5 0,000 0,01271912 0,07826649 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01271912 0,07806683 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01271912 0,07786819 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01271912 0,07767055 ! lung development GO:0030324 144 67 1,000 0,01281309 0,07804634 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01317972 0,08007676 ! urogenital system development GO:0001655 137 69 1,000 0,01355088 0,08212449 ! respiratory tube development GO:0030323 150 70 1,000 0,01392657 0,08418924 ! appendage morphogenesis GO:0035107 135 70 1,000 0,01392657 0,08397824 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 1,000 0,01430674 0,08605506 ! appendage development GO:0048736 136 71 1,000 0,01430674 0,08584046 GO:0060173|limb development, ! respiratory system development GO:0060541 153 72 1,000 0,01469139 0,08792906 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01524371 0,09100838 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01524371 0,09078311 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01524371 0,09055895 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01524371 0,0903359 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01524371 0,09011394 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01524371 0,08989308 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01524371 0,08967329 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01524371 0,08945457 ! sleep GO:0030431 13 6 0,000 0,01524371 0,08923692 ! response to oxygen radical GO:0000305 11 6 0,000 0,01524371 0,08902033 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01524371 0,08880478 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01524371 0,08859028 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01524371 0,08837681 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01524371 0,08816436 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01524371 0,08795294 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01524371 0,08774253 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01524371 0,08753312 ! forebrain regionalization GO:0021871 8 6 0,000 0,01524371 0,0873247 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01524371 0,08711728 ! male meiosis GO:0007140 7 6 0,000 0,01524371 0,08691084 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01524371 0,08670538 ! response to zinc ion GO:0010043 9 6 0,000 0,01524371 0,08650089 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01524371 0,08629735 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01524371 0,08609478 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01524371 0,08589315 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01524371 0,08569247 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01524371 0,08549272 ! malate metabolic process GO:0006108 11 6 0,000 0,01524371 0,0852939 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01524371 0,085096 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01524371 0,08489902 ! protein refolding GO:0042026 15 6 0,000 0,01524371 0,08470295 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01524371 0,08450778 ! opsonization GO:0008228 8 6 0,000 0,01524371 0,08431351 ! mating behavior GO:0007617 7 6 0,000 0,01524371 0,08412013 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01524371 0,08392763 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01524371 0,08373602 ! equilibrioception GO:0050957 14 6 0,000 0,01524371 0,08354527 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01524371 0,0833554 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01524371 0,08316638 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01524371 0,08297823 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01524371 0,08279092 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01524371 0,08260445 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01524371 0,08241882 ! toxin metabolic process GO:0009404 11 6 0,000 0,01524371 0,08223403 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01524371 0,08205006 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01524371 0,08186691 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01524371 0,08168458 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01524371 0,08150306 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01524371 0,08132234 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01524371 0,08114242 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01524371 0,0809633 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01524371 0,08078497 ! thymic T cell selection GO:0045061 12 6 0,000 0,01524371 0,08060742 ! protein lipoylation GO:0009249 10 6 0,000 0,01524371 0,08043065 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01524371 0,08025465 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01524371 0,08007942 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01524371 0,07990496 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01524371 0,07973125 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01524371 0,0795583 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,01524371 0,07938609 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01524371 0,07921463 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01524371 0,07904391 ! hyperosmotic response GO:0006972 9 6 0,000 0,01524371 0,07887393 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01524371 0,07870467 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01524371 0,07853614 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01524371 0,07836832 ! urea metabolic process GO:0019627 7 6 0,000 0,01524371 0,07820123 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01524371 0,07803484 ! neutrophil activation GO:0042119 8 6 0,000 0,01524371 0,07786916 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01524371 0,07770419 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01524371 0,07753991 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01524371 0,07737632 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01524371 0,07721342 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01524371 0,07705121 ! neuron apoptosis GO:0051402 9 6 0,000 0,01524371 0,07688968 ! nucleoside salvage GO:0043174 9 6 0,000 0,01524371 0,07672882 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01524371 0,07656863 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01524371 0,07640912 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01524371 0,07625026 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01524371 0,07609207 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01524371 0,07593453 ! carnitine transport GO:0015879 10 6 0,000 0,01524371 0,07577764 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01524371 0,07562139 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01524371 0,07546579 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01524371 0,07531083 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01524371 0,07515651 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01524371 0,07500281 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01524371 0,07484975 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01524371 0,0746973 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01524371 0,07454548 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01524371 0,07439427 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01524371 0,07424368 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01524371 0,07409369 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 0,000 0,01524371 0,07394431 ! response to UV-C GO:0010225 11 6 0,000 0,01524371 0,07379552 ! astrocyte development GO:0014002 15 6 0,000 0,01524371 0,07364734 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01524371 0,07349975 ! interaction with symbiont GO:0051702 13 6 0,000 0,01524371 0,07335275 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01524371 0,07320634 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01524371 0,07306051 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01524371 0,07291526 ! response to copper ion GO:0046688 10 6 0,000 0,01524371 0,07277059 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01524371 0,07262649 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01524371 0,07248296 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01524371 0,07233999 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01524371 0,07219759 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01524371 0,07205575 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01524371 0,07191446 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01524371 0,07177373 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01524371 0,07163355 ! hair follicle maturation GO:0048820 7 6 0,000 0,01524371 0,07149391 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01524371 0,07135482 ! Schwann cell development GO:0014044 15 6 0,000 0,01524371 0,07121626 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01524371 0,07107825 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01524371 0,07094077 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01524371 0,07080381 ! subpallium development GO:0021544 10 6 0,000 0,01524371 0,07066739 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01524371 0,07053149 ! histone ubiquitination GO:0016574 8 6 0,000 0,01524371 0,07039611 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01524371 0,07026126 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01524371 0,07012691 ! G2 phase GO:0051319 16 6 0,000 0,01524371 0,06999308 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01524371 0,06985976 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01524371 0,06972695 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01524371 0,06959464 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01524371 0,06946283 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01524371 0,06933152 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01524371 0,06920071 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01524371 0,06907039 ! receptor internalization GO:0031623 10 6 0,000 0,01524371 0,06894056 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01524371 0,06881121 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01524371 0,06868235 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01524371 0,06855397 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01524371 0,06842607 ! protein deubiquitination GO:0016579 14 6 0,000 0,01524371 0,06829865 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01524371 0,0681717 ! protein destabilization GO:0031648 9 6 0,000 0,01524371 0,06804522 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01524371 0,06791921 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01524371 0,06779367 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01524371 0,06766859 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01524371 0,06754397 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01524371 0,06741981 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01524371 0,0672961 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01524371 0,06717285 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01524371 0,06705005 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01524371 0,06692769 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01524371 0,06680578 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01524371 0,06668432 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01524371 0,0665633 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01524371 0,06644271 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01524371 0,06632256 ! catecholamine transport GO:0051937 9 6 0,000 0,01524371 0,06620284 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01524371 0,06608356 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01524371 0,0659647 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01524371 0,06584628 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01524371 0,06572827 ! maternal placenta development GO:0001893 12 6 0,000 0,01524371 0,06561069 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01524371 0,06549353 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01524371 0,06537678 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01524371 0,06526045 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01524371 0,06514454 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01524371 0,06502903 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01524371 0,06491394 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01547399 0,06577811 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,01547399 0,0656621 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 1,000 0,01547399 0,0655465 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01587189 0,06711383 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01587189 0,06699608 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,01587189 0,06687875 ! meiotic cell cycle GO:0051321 122 75 1,000 0,01587189 0,06676183 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01627416 0,06833445 ! blood coagulation GO:0007596 146 78 1,000 0,01709173 0,07164232 GO:0050817|coagulation, ! tRNA transcription GO:0009304 14 7 0,000 0,01776194 0,07432212 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01776194 0,07419309 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01776194 0,07406451 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01776194 0,07393637 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01776194 0,07380867 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01776194 0,07368142 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01776194 0,0735546 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01776194 0,07342822 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01776194 0,07330227 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01776194 0,07317675 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01776194 0,07305166 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01776194 0,072927 GO:0070193|synaptonemal complex organization, ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01776194 0,07280276 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01776194 0,07267895 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01776194 0,07255555 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01776194 0,07243258 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01776194 0,07231002 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01776194 0,07218787 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01776194 0,07206614 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01776194 0,07194482 ! glycolipid transport GO:0046836 10 7 0,000 0,01776194 0,0718239 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01776194 0,07170339 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01776194 0,07158329 ! neuron adhesion GO:0007158 12 7 0,000 0,01776194 0,07146358 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01776194 0,07134428 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01776194 0,07122537 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01776194 0,07110686 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01776194 0,07098874 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01776194 0,07087101 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01776194 0,07075368 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01776194 0,07063673 ! mRNA stabilization GO:0048255 18 7 0,000 0,01776194 0,07052017 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01776194 0,07040399 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01776194 0,07028819 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01776194 0,07017278 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01776194 0,07005774 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01776194 0,06994308 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01776194 0,06982879 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01776194 0,06971488 ! lipoprotein transport GO:0042953 14 7 0,000 0,01776194 0,06960134 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01776194 0,06948817 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01776194 0,06937536 ! rhythmic behavior GO:0007622 15 7 0,000 0,01776194 0,06926292 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01776194 0,06915084 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01776194 0,06903913 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01776194 0,06892778 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01776194 0,06881678 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01776194 0,06870614 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01776194 0,06859586 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01776194 0,06848593 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01776194 0,06837635 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01776194 0,06826713 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01776194 0,06815825 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01776194 0,06804972 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01776194 0,06794153 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01776194 0,06783369 ! spinal cord patterning GO:0021511 13 7 0,000 0,01776194 0,06772618 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01776194 0,06761902 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01776194 0,0675122 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01776194 0,06740571 ! adrenal gland development GO:0030325 17 7 0,000 0,01776194 0,06729956 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01776194 0,06719375 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01776194 0,06708826 ! ovulation GO:0030728 9 7 0,000 0,01776194 0,06698311 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01776194 0,06687828 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01776194 0,06677378 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01776194 0,06666961 ! microtubule nucleation GO:0007020 20 7 0,000 0,01776194 0,06656577 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01776194 0,06646224 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01776194 0,06635904 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01776194 0,06625616 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01776194 0,06615359 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01776194 0,06605135 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01776194 0,06594942 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01776194 0,0658478 ! galactose metabolic process GO:0006012 13 7 0,000 0,01776194 0,0657465 ! vesicle fusion GO:0006906 17 7 0,000 0,01776194 0,0656455 ! response to dietary excess GO:0002021 8 7 0,000 0,01776194 0,06554482 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01776194 0,06544444 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01776194 0,06534438 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01776194 0,06524461 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01776194 0,06514516 ! organ growth GO:0035265 15 7 0,000 0,01776194 0,065046 ! purine salvage GO:0043101 10 7 0,000 0,01776194 0,06494715 ! nucleoside transport GO:0015858 8 7 0,000 0,01776194 0,06484859 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01776194 0,06475034 ! parturition GO:0007567 14 7 0,000 0,01776194 0,06465238 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01776194 0,06455472 ! rRNA modification GO:0000154 14 7 0,000 0,01776194 0,06445735 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01776194 0,06436027 ! spindle checkpoint GO:0031577 15 7 0,000 0,01776194 0,06426349 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01776194 0,064167 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01776194 0,0640708 ! macrophage differentiation GO:0030225 11 7 0,000 0,01776194 0,06397488 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01776194 0,06387926 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01776194 0,06378391 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01776194 0,06368886 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01776194 0,06359408 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01776194 0,06349959 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01776194 0,06340537 ! fibrinolysis GO:0042730 10 7 0,000 0,01776194 0,06331144 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01776194 0,06321778 ! eating behavior GO:0042755 7 7 0,000 0,01776194 0,0631244 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01776194 0,0630313 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01776194 0,06293847 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01776194 0,06284591 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01776194 0,06275363 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01776194 0,06266162 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01776194 0,06256987 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01776194 0,06247839 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01776194 0,06238719 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01776194 0,06229624 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01776194 0,06220556 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01776194 0,06211515 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01776194 0,062025 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01776194 0,0619351 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01776194 0,06184547 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01776194 0,0617561 ! regulation of meiosis GO:0040020 12 7 0,000 0,01776194 0,06166699 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01776194 0,06157813 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01776194 0,06148953 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01776194 0,06140118 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01776194 0,06131309 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01776194 0,06122525 ! transcription termination GO:0006353 13 7 0,000 0,01776194 0,06113766 ! response to tumor cell GO:0002347 13 7 0,000 0,01776194 0,06105032 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01776194 0,06096323 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01776194 0,06087638 ! anaphase GO:0051322 17 7 0,000 0,01776194 0,06078979 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01776194 0,06070344 ! axonal fasciculation GO:0007413 18 7 0,000 0,01776194 0,06061734 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01776194 0,06053148 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01776194 0,06044586 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01776194 0,06036048 ! diuresis GO:0030146 12 7 0,000 0,01776194 0,06027535 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01776194 0,06019045 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01776194 0,0601058 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01776194 0,06002138 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01776194 0,0599372 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01776194 0,05985325 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01776194 0,05976954 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01776194 0,05968606 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01776194 0,05960282 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01776194 0,05951981 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01776194 0,05943703 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01776194 0,05935447 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01776194 0,05927215 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01776194 0,05919006 ! lymph node development GO:0048535 10 7 0,000 0,01776194 0,05910819 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01776194 0,05902655 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01776194 0,05894513 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01776194 0,05886394 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01776194 0,05878297 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01776194 0,05870223 ! adult feeding behavior GO:0008343 9 7 0,000 0,01776194 0,0586217 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01776194 0,0585414 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01776194 0,05846132 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01776194 0,05838145 ! muscle adaptation GO:0043500 14 7 0,000 0,01776194 0,0583018 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01776194 0,05822237 ! retina homeostasis GO:0001895 12 7 0,000 0,01776194 0,05814316 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01776194 0,05806416 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01776194 0,05798538 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01776194 0,0579068 ! protein prenylation GO:0018342 18 7 0,000 0,01776194 0,05782845 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01776194 0,0577503 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01776194 0,05767236 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01776194 0,05759464 ! muscle cell differentiation GO:0042692 159 80 1,000 0,01792648 0,05804994 ! response to hypoxia GO:0001666 171 81 1,000 0,01835024 0,0593423 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,01835024 0,05926265 ! T cell activation GO:0042110 168 81 1,000 0,01835024 0,05918321 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,01835024 0,05910398 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01877823 0,06040162 ! response to oxygen levels GO:0070482 176 83 1,000 0,01921042 0,06170929 ! hemostasis GO:0007599 158 84 1,000 0,01964678 0,06302688 ! negative regulation of transport GO:0051051 153 84 1,000 0,01964678 0,06294296 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02027381 0,06486539 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02027381 0,06477925 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,02027381 0,06469334 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02027381 0,06460765 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02027381 0,06452219 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02027381 0,06443696 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02027381 0,06435195 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02027381 0,06426716 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02027381 0,0641826 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02027381 0,06409826 ! meiotic prophase I GO:0007128 13 8 0,000 0,02027381 0,06401414 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02027381 0,06393024 ! oligopeptide transport GO:0006857 15 8 0,000 0,02027381 0,06384656 ! UTP metabolic process GO:0046051 8 8 0,000 0,02027381 0,0637631 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02027381 0,06367986 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02027381 0,06359684 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02027381 0,06351403 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02027381 0,06343144 ! succinate metabolic process GO:0006105 14 8 0,000 0,02027381 0,06334906 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02027381 0,06326689 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02027381 0,06318494 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02027381 0,0631032 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02027381 0,06302167 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02027381 0,06294035 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02027381 0,06285925 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02027381 0,06277835 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02027381 0,06269765 ! reflex GO:0060004 16 8 0,000 0,02027381 0,06261717 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02027381 0,06253689 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02027381 0,06245682 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02027381 0,06237695 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02027381 0,06229729 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02027381 0,06221783 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02027381 0,06213857 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02027381 0,06205951 ! pigment granule organization GO:0048753 16 8 0,000 0,02027381 0,06198065 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02027381 0,061902 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02027381 0,06182354 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02027381 0,06174528 ! histidine metabolic process GO:0006547 16 8 0,000 0,02027381 0,06166723 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02027381 0,06158936 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02027381 0,0615117 ! glycine catabolic process GO:0006546 13 8 0,000 0,02027381 0,06143423 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02027381 0,06135695 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02027381 0,06127987 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02027381 0,06120298 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02027381 0,06112628 ! melanin metabolic process GO:0006582 15 8 0,000 0,02027381 0,06104978 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02027381 0,06097347 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02027381 0,06089735 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02027381 0,06082142 ! macrophage activation GO:0042116 12 8 0,000 0,02027381 0,06074567 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02027381 0,06067012 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02027381 0,06059475 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02027381 0,06051957 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02027381 0,06044458 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02027381 0,06036977 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02027381 0,06029515 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02027381 0,06022071 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02027381 0,06014646 ! osteoblast development GO:0002076 16 8 0,000 0,02027381 0,06007238 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02027381 0,05999849 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02027381 0,05992479 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02027381 0,05985126 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02027381 0,05977791 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02027381 0,05970474 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02027381 0,05963175 ! response to UV-B GO:0010224 16 8 0,000 0,02027381 0,05955894 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02027381 0,05948631 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02027381 0,05941386 ! intermediate filament organization GO:0045109 12 8 0,000 0,02027381 0,05934158 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02027381 0,05926947 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02027381 0,05919754 ! cellular extravasation GO:0045123 12 8 0,000 0,02027381 0,05912579 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02027381 0,05905421 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02027381 0,0589828 ! response to antibiotic GO:0046677 11 8 0,000 0,02027381 0,05891156 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02027381 0,0588405 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02027381 0,05876961 ! DNA topological change GO:0006265 12 8 0,000 0,02027381 0,05869889 ! response to tropane GO:0014073 15 8 0,000 0,02027381 0,05862834 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02027381 0,05855795 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02027381 0,05848774 ! melanosome transport GO:0032402 13 8 0,000 0,02027381 0,05841769 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,02027381 0,05834782 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02027381 0,05827811 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02027381 0,05820856 ! mast cell activation GO:0045576 14 8 0,000 0,02027381 0,05813918 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02027381 0,05806997 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02027381 0,05800092 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02027381 0,05793204 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02027381 0,05786332 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02027381 0,05779476 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02027381 0,05772636 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02027381 0,05765813 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02027381 0,05759005 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02027381 0,05752214 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02027381 0,05745439 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02027381 0,05738679 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02027381 0,05731936 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02027381 0,05725208 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02027381 0,05718496 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02027381 0,057118 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02027381 0,0570512 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02027381 0,05698455 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02027381 0,05691806 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02027381 0,05685172 ! hormone catabolic process GO:0042447 17 8 0,000 0,02027381 0,05678554 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02027381 0,05671951 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02027381 0,05665363 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02027381 0,05658791 ! ATP catabolic process GO:0006200 11 8 0,000 0,02027381 0,05652233 ! blastocyst growth GO:0001832 19 8 0,000 0,02027381 0,05645692 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02027381 0,05639165 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02027381 0,05632653 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02027381 0,05626156 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02027381 0,05619675 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02027381 0,05613208 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02027381 0,05606756 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02027381 0,05600319 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02027381 0,05593896 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02027381 0,05587489 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02027381 0,05581096 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02027381 0,05574717 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02027381 0,05568353 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02027381 0,05562004 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02027381 0,05555669 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02027381 0,05549349 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02027381 0,05543043 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02027381 0,05536751 ! tube morphogenesis GO:0035239 176 86 1,000 0,02053196 0,05600895 ! regulation of protein transport GO:0051223 154 87 1,000 0,02098072 0,0571683 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,02143357 0,05833615 ! gland development GO:0048732 206 88 1,000 0,02143357 0,05827024 ! regulation of neurological system process GO:0031644 148 88 1,000 0,02143357 0,05820447 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02189047 0,05937821 ! sex differentiation GO:0007548 145 90 1,000 0,02235142 0,06056026 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02277933 0,06165025 ! axon extension GO:0048675 15 9 0,000 0,02277933 0,06158098 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02277933 0,06151187 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02277933 0,06144291 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02277933 0,0613741 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02277933 0,06130545 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02277933 0,06123695 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02277933 0,06116861 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02277933 0,06110042 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02277933 0,06103238 ! phosphate transport GO:0006817 19 9 0,000 0,02277933 0,06096449 ! reproductive behavior GO:0019098 19 9 0,000 0,02277933 0,06089675 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02277933 0,06082916 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02277933 0,06076172 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02277933 0,06069443 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02277933 0,06062729 ! GTP metabolic process GO:0046039 9 9 0,000 0,02277933 0,0605603 ! RNA methylation GO:0001510 15 9 0,000 0,02277933 0,06049346 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02277933 0,06042676 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02277933 0,06036021 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02277933 0,06029381 ! artery development GO:0060840 24 9 0,000 0,02277933 0,06022755 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02277933 0,06016144 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02277933 0,06009548 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02277933 0,06002965 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02277933 0,05996398 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02277933 0,05989844 ! chemosensory behavior GO:0007635 20 9 0,000 0,02277933 0,05983305 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02277933 0,0597678 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02277933 0,05970269 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02277933 0,05963773 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02277933 0,05957291 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02277933 0,05950822 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02277933 0,05944368 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02277933 0,05937928 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02277933 0,05931501 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02277933 0,05925089 ! protein targeting to ER GO:0045047 22 9 0,000 0,02277933 0,0591869 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02277933 0,05912306 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02277933 0,05905935 ! T cell selection GO:0045058 23 9 0,000 0,02277933 0,05899577 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02277933 0,05893234 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02277933 0,05886904 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02277933 0,05880587 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02277933 0,05874284 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02277933 0,05867995 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02277933 0,05861719 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02277933 0,05855457 ! mannose metabolic process GO:0006013 13 9 0,000 0,02277933 0,05849207 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02277933 0,05842972 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02277933 0,05836749 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02277933 0,0583054 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02277933 0,05824344 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02277933 0,05818161 ! ruffle organization GO:0031529 15 9 0,000 0,02277933 0,05811991 ! retinol metabolic process GO:0042572 18 9 0,000 0,02277933 0,05805834 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02277933 0,0579969 ! behavioral fear response GO:0001662 22 9 0,000 0,02277933 0,0579356 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02277933 0,05787442 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02277933 0,05781337 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02277933 0,05775245 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02277933 0,05769166 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02277933 0,05763099 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02277933 0,05757046 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02277933 0,05751005 ! segment specification GO:0007379 13 9 0,000 0,02277933 0,05744976 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02277933 0,05738961 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02277933 0,05732957 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02277933 0,05726967 ! response to amine stimulus GO:0014075 13 9 0,000 0,02277933 0,05720989 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02277933 0,05715023 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02277933 0,0570907 ! erythrocyte development GO:0048821 15 9 0,000 0,02277933 0,05703129 ! gas homeostasis GO:0033483 16 9 0,000 0,02277933 0,05697201 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02277933 0,05691285 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02277933 0,05685381 ! renal water homeostasis GO:0003091 14 9 0,000 0,02277933 0,05679489 ! postreplication repair GO:0006301 22 9 0,000 0,02277933 0,0567361 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02277933 0,05667743 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02277933 0,05661888 ! icosanoid secretion GO:0032309 15 9 0,000 0,02277933 0,05656045 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02277933 0,05650214 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02277933 0,05644395 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02277933 0,05638588 ! regulation of cell division GO:0051302 15 9 0,000 0,02277933 0,05632793 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02277933 0,0562701 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02277933 0,05621238 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02277933 0,05615479 ! sterol catabolic process GO:0016127 11 9 0,000 0,02277933 0,05609731 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02277933 0,05603995 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02277933 0,05598271 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02277933 0,05592559 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02277933 0,05586858 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02277933 0,05581168 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02277933 0,05575491 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02277933 0,05569825 GO:0050879|multicellular organismal movement, ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02277933 0,0556417 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02277933 0,05558527 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02277933 0,05552895 ! pigment granule transport GO:0051904 17 9 0,000 0,02277933 0,05547275 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02277933 0,05541666 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02277933 0,05536068 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02277933 0,05530482 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02277933 0,05524907 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02277933 0,05519343 ! mitochondrion localization GO:0051646 15 9 0,000 0,02277933 0,0551379 ! forebrain development GO:0030900 188 95 1,000 0,0247159 0,05976529 ! leukocyte differentiation GO:0002521 202 96 1,000 0,02520059 0,06087614 ! mRNA transport GO:0051028 169 96 1,000 0,02520059 0,06081508 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02527853 0,06094204 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02527853 0,06088104 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02527853 0,06082015 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02527853 0,0607594 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02527853 0,06069876 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02527853 0,06063824 ! synapsis GO:0007129 13 10 0,000 0,02527853 0,06057784 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02527853 0,06051757 ! N-glycan processing GO:0006491 20 10 0,000 0,02527853 0,06045741 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02527853 0,06039737 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02527853 0,06033746 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02527853 0,06027766 ! social behavior GO:0035176 24 10 0,000 0,02527853 0,06021798 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02527853 0,06015841 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02527853 0,06009897 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02527853 0,06003964 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02527853 0,05998043 ! androgen metabolic process GO:0008209 17 10 0,000 0,02527853 0,05992133 ! phospholipid efflux GO:0033700 16 10 0,000 0,02527853 0,05986236 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02527853 0,0598035 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02527853 0,05974475 ! lung alveolus development GO:0048286 26 10 0,000 0,02527853 0,05968612 ! pathogenesis GO:0009405 13 10 0,000 0,02527853 0,0596276 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02527853 0,0595692 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02527853 0,05951091 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02527853 0,05945274 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02527853 0,05939468 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02527853 0,05933674 ! endoderm development GO:0007492 16 10 0,000 0,02527853 0,0592789 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02527853 0,05922118 ! arginine catabolic process GO:0006527 13 10 0,000 0,02527853 0,05916357 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02527853 0,05910608 ! proline metabolic process GO:0006560 13 10 0,000 0,02527853 0,05904869 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02527853 0,05899142 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02527853 0,05893426 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02527853 0,05887721 ! V(D)J recombination GO:0033151 28 10 0,000 0,02527853 0,05882027 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02527853 0,05876343 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02527853 0,05870671 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02527853 0,0586501 ! B cell proliferation GO:0042100 18 10 0,000 0,02527853 0,0585936 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02527853 0,0585372 ! multicellular organism growth GO:0035264 18 10 0,000 0,02527853 0,05848092 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02527853 0,05842474 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02527853 0,05836867 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02527853 0,05831271 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02527853 0,05825685 ! macroautophagy GO:0016236 17 10 0,000 0,02527853 0,05820111 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02527853 0,05814546 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02527853 0,05808993 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02527853 0,0580345 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02527853 0,05797918 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02527853 0,05792396 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02527853 0,05786884 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02527853 0,05781384 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02527853 0,05775893 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02527853 0,05770413 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02527853 0,05764944 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02527853 0,05759484 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02527853 0,05754035 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02527853 0,05748597 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02527853 0,05743169 ! response to dsRNA GO:0043331 20 10 0,000 0,02527853 0,0573775 ! DNA ligation GO:0006266 19 10 0,000 0,02527853 0,05732343 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02527853 0,05726945 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02527853 0,05721557 ! melanosome localization GO:0032400 16 10 0,000 0,02527853 0,0571618 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02527853 0,05710813 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02527853 0,05705455 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02527853 0,05700108 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02527853 0,05694771 ! mRNA cleavage GO:0006379 17 10 0,000 0,02527853 0,05689444 ! protein sumoylation GO:0016925 15 10 0,000 0,02527853 0,05684127 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02527853 0,05678819 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02527853 0,05673522 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02527853 0,05668234 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02527853 0,05662957 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02527853 0,05657689 ! salivary gland development GO:0007431 27 10 0,000 0,02527853 0,05652431 ! prophase GO:0051324 15 10 0,000 0,02527853 0,05647182 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02527853 0,05641944 ! apical protein localization GO:0045176 15 10 0,000 0,02527853 0,05636715 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02527853 0,05631496 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02527853 0,05626286 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02527853 0,05621086 ! midbrain development GO:0030901 13 10 0,000 0,02527853 0,05615896 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02527853 0,05610715 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02527853 0,05605544 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02527853 0,05600383 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02527853 0,0559523 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02527853 0,05590088 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02527853 0,05584955 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02527853 0,05579831 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02527853 0,05574716 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02527853 0,05569611 ! oocyte development GO:0048599 17 10 0,000 0,02527853 0,05564516 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02527853 0,05559429 ! blastocyst formation GO:0001825 17 10 0,000 0,02527853 0,05554352 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02527853 0,05549284 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02527853 0,05544226 ! activation of innate immune response GO:0002218 12 10 0,000 0,02527853 0,05539176 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02527853 0,05534136 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02527853 0,05529105 ! response to nicotine GO:0035094 20 10 0,000 0,02527853 0,05524083 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02527853 0,0551907 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02527853 0,05514067 ! localization within membrane GO:0051668 20 10 0,000 0,02527853 0,05509072 ! protein ubiquitination GO:0016567 217 97 1,000 0,02568916 0,05593496 ! hormone metabolic process GO:0042445 157 97 1,000 0,02568916 0,05588438 ! regulation of protein localization GO:0032880 176 97 1,000 0,02568916 0,0558339 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02667785 0,05793042 GO:0060538|skeletal muscle organ development, ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02777143 0,06025073 ! respiratory burst GO:0045730 17 11 0,000 0,02777143 0,06019645 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02777143 0,06014227 ! neuron fate specification GO:0048665 17 11 0,000 0,02777143 0,06008818 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02777143 0,06003419 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02777143 0,0599803 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02777143 0,05992651 ! thyroid gland development GO:0030878 26 11 0,000 0,02777143 0,05987281 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02777143 0,05981921 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02777143 0,0597657 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02777143 0,05971229 ! response to pain GO:0048265 24 11 0,000 0,02777143 0,05965898 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02777143 0,05960576 ! T cell proliferation GO:0042098 26 11 0,000 0,02777143 0,05955264 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02777143 0,05949961 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02777143 0,05944667 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02777143 0,05939383 ! bone resorption GO:0045453 16 11 0,000 0,02777143 0,05934108 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02777143 0,05928843 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02777143 0,05923587 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02777143 0,0591834 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02777143 0,05913102 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02777143 0,05907874 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02777143 0,05902655 GO:0050931|pigment cell differentiation, ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02777143 0,05897445 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02777143 0,05892245 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02777143 0,05887054 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02777143 0,05881871 ! lipid digestion GO:0044241 18 11 0,000 0,02777143 0,05876698 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02777143 0,05871534 ! UV protection GO:0009650 19 11 0,000 0,02777143 0,05866379 ! adult heart development GO:0007512 14 11 0,000 0,02777143 0,05861233 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02777143 0,05856096 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02777143 0,05850968 ! temperature homeostasis GO:0001659 17 11 0,000 0,02777143 0,05845849 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02777143 0,05840739 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02777143 0,05835638 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02777143 0,05830546 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02777143 0,05825463 ! regulation of organ growth GO:0046620 13 11 0,000 0,02777143 0,05820388 ! pigment granule localization GO:0051875 20 11 0,000 0,02777143 0,05815323 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02777143 0,05810266 ! vasoconstriction GO:0042310 18 11 0,000 0,02777143 0,05805218 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02777143 0,05800179 ! embryonic axis specification GO:0000578 18 11 0,000 0,02777143 0,05795148 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02777143 0,05790126 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02777143 0,05785113 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02777143 0,05780109 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02777143 0,05775113 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02777143 0,05770126 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02777143 0,05765147 ! zymogen activation GO:0031638 15 11 0,000 0,02777143 0,05760177 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02777143 0,05755216 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02777143 0,05750263 ! nucleosome positioning GO:0016584 15 11 0,000 0,02777143 0,05745319 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02777143 0,05740383 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02777143 0,05735456 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02777143 0,05730537 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02777143 0,05725626 ! acid secretion GO:0046717 18 11 0,000 0,02777143 0,05720724 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02777143 0,0571583 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02777143 0,05710945 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02777143 0,05706068 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02777143 0,05701199 ! oocyte differentiation GO:0009994 18 11 0,000 0,02777143 0,05696339 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02777143 0,05691487 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02777143 0,05686643 ! cholesterol efflux GO:0033344 19 11 0,000 0,02777143 0,05681808 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02777143 0,0567698 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02777143 0,05672161 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02777143 0,0566735 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02777143 0,05662547 ! embryonic gut development GO:0048566 15 11 0,000 0,02777143 0,05657753 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02777143 0,05652966 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02777143 0,05648187 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02777143 0,05643417 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02777143 0,05638655 ! defense response to fungus GO:0050832 13 11 0,000 0,02777143 0,056339 ! developmental induction GO:0031128 19 11 0,000 0,02777143 0,05629154 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02777143 0,05624416 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02777143 0,05619685 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02777143 0,05614963 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02777143 0,05610248 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02777143 0,05605542 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02777143 0,05600843 ! nucleus localization GO:0051647 19 11 0,000 0,02777143 0,05596152 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02777143 0,05591469 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03025803 0,06087025 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03025803 0,0608194 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03025803 0,06076863 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,03025803 0,06071795 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03025803 0,06066735 ! virus-host interaction GO:0019048 29 12 0,000 0,03025803 0,06061683 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03025803 0,0605664 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03025803 0,06051606 ! cartilage condensation GO:0001502 20 12 0,000 0,03025803 0,0604658 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03025803 0,06041562 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03025803 0,06036552 ! protein complex disassembly GO:0043241 27 12 0,000 0,03025803 0,06031551 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03025803 0,06026558 ! hippocampus development GO:0021766 26 12 0,000 0,03025803 0,06021573 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03025803 0,06016597 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03025803 0,06011628 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03025803 0,06006668 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03025803 0,06001716 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03025803 0,05996773 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03025803 0,05991837 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03025803 0,05986909 ! drug transport GO:0015893 16 12 0,000 0,03025803 0,0598199 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03025803 0,05977079 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03025803 0,05972175 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03025803 0,0596728 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03025803 0,05962393 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03025803 0,05957514 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03025803 0,05952643 ! forebrain cell migration GO:0021885 21 12 0,000 0,03025803 0,05947779 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03025803 0,05942924 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03025803 0,05938077 ! entry into host cell GO:0030260 32 12 0,000 0,03025803 0,05933237 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03025803 0,05928405 ! monoamine transport GO:0015844 18 12 0,000 0,03025803 0,05923582 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03025803 0,05918766 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03025803 0,05913958 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03025803 0,05909157 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03025803 0,05904365 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03025803 0,0589958 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03025803 0,05894803 ! protein homotetramerization GO:0051289 21 12 0,000 0,03025803 0,05890034 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03025803 0,05885272 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03025803 0,05880518 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03025803 0,05875772 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03025803 0,05871034 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03025803 0,05866303 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03025803 0,0586158 ! cranial nerve development GO:0021545 20 12 0,000 0,03025803 0,05856864 ! fucose catabolic process GO:0019317 22 12 0,000 0,03025803 0,05852156 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03025803 0,05847455 ! histone acetylation GO:0016573 26 12 0,000 0,03025803 0,05842762 ! histone methylation GO:0016571 26 12 0,000 0,03025803 0,05838077 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03025803 0,05833399 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03025803 0,05828728 ! gland morphogenesis GO:0022612 29 12 0,000 0,03025803 0,05824065 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03025803 0,0581941 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03025803 0,05814762 ! T cell homeostasis GO:0043029 25 12 0,000 0,03025803 0,05810121 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03025803 0,05805488 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03025803 0,05800862 ! spleen development GO:0048536 22 12 0,000 0,03025803 0,05796244 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03025803 0,05791632 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03025803 0,05787028 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03025803 0,05782432 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03025803 0,05777843 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03025803 0,05773261 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03025803 0,05768686 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03025803 0,05764119 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03025803 0,05759558 ! response to cold GO:0009409 17 12 0,000 0,03025803 0,05755005 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03025803 0,0575046 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03025803 0,05745921 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03273835 0,06212025 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03273835 0,0620713 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03273835 0,06202242 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03273835 0,06197362 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03273835 0,0619249 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03273835 0,06187626 ! lipid localization GO:0010876 28 13 0,000 0,03273835 0,06182769 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03273835 0,0617792 ! organelle fusion GO:0048284 32 13 0,000 0,03273835 0,06173078 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03273835 0,06168244 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03273835 0,06163418 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03273835 0,06158599 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03273835 0,06153787 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03273835 0,06148983 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03273835 0,06144187 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03273835 0,06139398 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03273835 0,06134617 ! methionine metabolic process GO:0006555 27 13 0,000 0,03273835 0,06129843 ! plasma membrane organization GO:0007009 24 13 0,000 0,03273835 0,06125076 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03273835 0,06120317 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03273835 0,06115565 ! Golgi organization GO:0007030 24 13 0,000 0,03273835 0,0611082 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03273835 0,06106083 ! response to X-ray GO:0010165 25 13 0,000 0,03273835 0,06101354 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03273835 0,06096631 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03273835 0,06091916 ! exocrine system development GO:0035272 32 13 0,000 0,03273835 0,06087208 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,03273835 0,06082508 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03273835 0,06077815 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03273835 0,06073128 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03273835 0,0606845 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03273835 0,06063778 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03273835 0,06059114 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03273835 0,06054456 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03273835 0,06049806 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03273835 0,06045163 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03273835 0,06040527 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03273835 0,06035899 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03273835 0,06031277 ! ribosome assembly GO:0042255 17 13 0,000 0,03273835 0,06026662 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,03273835 0,06022055 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03273835 0,06017454 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03273835 0,06012861 ! chromatin silencing GO:0006342 26 13 0,000 0,03273835 0,06008274 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03273835 0,06003695 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03273835 0,05999122 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03273835 0,05994557 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03273835 0,05989998 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03273835 0,05985447 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03273835 0,05980902 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03273835 0,05976364 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03273835 0,05971833 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03273835 0,05967309 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03273835 0,05962792 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03273835 0,05958281 ! embryonic placenta development GO:0001892 23 13 0,000 0,03273835 0,05953777 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03273835 0,05949281 ! insulin secretion GO:0030073 23 13 0,000 0,03273835 0,05944791 ! actin filament polymerization GO:0030041 24 13 0,000 0,03273835 0,05940307 ! acrosome reaction GO:0007340 18 13 0,000 0,03273835 0,05935831 ! rRNA transcription GO:0009303 25 14 0,000 0,03521241 0,06379599 ! lactation GO:0007595 26 14 0,000 0,03521241 0,06374798 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03521241 0,06370005 ! reproductive cellular process GO:0048610 20 14 0,000 0,03521241 0,06365219 ! tRNA modification GO:0006400 20 14 0,000 0,03521241 0,06360441 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03521241 0,06355669 ! regulation of S phase GO:0033261 23 14 0,000 0,03521241 0,06350905 ! water transport GO:0006833 21 14 0,000 0,03521241 0,06346147 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 25 14 0,000 0,03521241 0,06341397 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03521241 0,06336654 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03521241 0,06331918 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03521241 0,0632719 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03521241 0,06322468 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03521241 0,06317753 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03521241 0,06313045 ! palate development GO:0060021 31 14 0,000 0,03521241 0,06308345 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03521241 0,06303651 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03521241 0,06298964 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03521241 0,06294284 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03521241 0,06289612 ! arginine metabolic process GO:0006525 17 14 0,000 0,03521241 0,06284946 ! regulation of heart rate GO:0002027 24 14 0,000 0,03521241 0,06280287 ! organic alcohol transport GO:0015850 29 14 0,000 0,03521241 0,06275635 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03521241 0,0627099 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03521241 0,06266351 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03521241 0,0626172 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03521241 0,06257095 ! L-amino acid transport GO:0015807 30 14 0,000 0,03521241 0,06252477 ! bone mineralization GO:0030282 17 14 0,000 0,03521241 0,06247866 ! stem cell development GO:0048864 43 14 0,000 0,03521241 0,06243262 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03521241 0,06238665 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03521241 0,06234074 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03521241 0,0622949 ! cerebellum development GO:0021549 21 14 0,000 0,03521241 0,06224913 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03521241 0,06220343 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03521241 0,06215779 ! response to gamma radiation GO:0010332 28 14 0,000 0,03521241 0,06211222 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03521241 0,06206672 ! cofactor transport GO:0051181 26 14 0,000 0,03521241 0,06202128 ! NADP metabolic process GO:0006739 24 14 0,000 0,03521241 0,06197591 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03521241 0,06193061 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03521241 0,06188537 ! intestinal absorption GO:0050892 25 14 0,000 0,03521241 0,0618402 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03521241 0,06179509 ! oxygen transport GO:0015671 21 14 0,000 0,03521241 0,06175005 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03521241 0,06170508 ! male genitalia development GO:0030539 24 14 0,000 0,03521241 0,06166017 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03521241 0,06161532 ! regulation of axon extension GO:0030516 37 14 0,000 0,03521241 0,06157054 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03521241 0,06152583 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03521241 0,06148118 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03768023 0,0657423 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03768023 0,06569466 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03768023 0,06564709 ! superoxide anion generation GO:0042554 20 15 0,000 0,03768023 0,06559959 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03768023 0,06555216 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03768023 0,06550479 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03768023 0,0654575 ! copper ion transport GO:0006825 20 15 0,000 0,03768023 0,06541027 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03768023 0,06536311 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03768023 0,06531602 ! sulfate transport GO:0008272 23 15 0,000 0,03768023 0,06526899 ! response to cAMP GO:0051591 22 15 0,000 0,03768023 0,06522204 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03768023 0,06517515 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03768023 0,06512833 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03768023 0,06508157 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03768023 0,06503489 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03768023 0,06498827 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03768023 0,06494171 ! pituitary gland development GO:0021983 29 15 0,000 0,03768023 0,06489523 ! vesicle coating GO:0006901 33 15 0,000 0,03768023 0,06484881 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03768023 0,06480245 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03768023 0,06475617 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03768023 0,06470994 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03768023 0,06466379 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03768023 0,0646177 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03768023 0,06457168 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03768023 0,06452572 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03768023 0,06447982 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03768023 0,064434 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03768023 0,06438823 ! histone deacetylation GO:0016575 20 15 0,000 0,03768023 0,06434253 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03768023 0,0642969 ! tissue regeneration GO:0042246 26 15 0,000 0,03768023 0,06425133 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03768023 0,06420583 ! water homeostasis GO:0030104 27 15 0,000 0,03768023 0,06416039 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03768023 0,06411502 ! muscle maintenance GO:0046716 26 15 0,000 0,03768023 0,0640697 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03768023 0,06402446 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03768023 0,06397927 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03768023 0,06393416 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03768023 0,0638891 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03768023 0,06384411 ! cell killing GO:0001906 29 15 0,000 0,03768023 0,06379918 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03768023 0,06375431 ! detection of bacterium GO:0016045 18 15 0,000 0,03768023 0,06370951 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03768023 0,06366477 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03768023 0,06362009 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03768023 0,06357548 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03768023 0,06353093 ! peptide hormone processing GO:0016486 23 15 0,000 0,03768023 0,06348644 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04014181 0,06758657 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04014181 0,0675393 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04014181 0,06749211 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04014181 0,06744498 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04014181 0,06739791 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04014181 0,06735091 ! bone remodeling GO:0046849 27 16 0,000 0,04014181 0,06730398 ! filopodium assembly GO:0046847 32 16 0,000 0,04014181 0,06725711 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04014181 0,0672103 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04014181 0,06716356 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04014181 0,06711689 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04014181 0,06707028 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04014181 0,06702374 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04014181 0,06697726 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04014181 0,06693084 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04014181 0,06688449 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04014181 0,0668382 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04014181 0,06679198 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04014181 0,06674582 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04014181 0,06669973 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04014181 0,0666537 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04014181 0,06660773 ! response to osmotic stress GO:0006970 25 16 0,000 0,04014181 0,06656182 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04014181 0,06651598 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04014181 0,0664702 ! fructose metabolic process GO:0006000 25 16 0,000 0,04014181 0,06642449 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04014181 0,06637883 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04014181 0,06633324 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04014181 0,06628772 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04014181 0,06624225 ! axon cargo transport GO:0008088 43 16 0,000 0,04014181 0,06619685 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04014181 0,06615151 ! DNA replication initiation GO:0006270 27 16 0,000 0,04014181 0,06610623 ! neuron recognition GO:0008038 35 16 0,000 0,04014181 0,06606102 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04014181 0,06601586 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04014181 0,06597077 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04014181 0,06592574 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04014181 0,06588077 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04014181 0,06583586 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04014181 0,06579101 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04014181 0,06574623 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04014181 0,0657015 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04014181 0,06565684 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04014181 0,06561223 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04014181 0,06556769 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04014181 0,06552321 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04014181 0,06547878 ! defense response to virus GO:0051607 37 16 0,000 0,04014181 0,06543442 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04259718 0,06938986 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04259718 0,06934291 ! metencephalon development GO:0022037 30 17 0,000 0,04259718 0,06929603 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04259718 0,06924921 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04259718 0,06920245 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04259718 0,06915575 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04259718 0,06910912 ! inositol metabolic process GO:0006020 28 17 0,000 0,04259718 0,06906255 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04259718 0,06901604 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04259718 0,0689696 ! glial cell development GO:0021782 27 17 0,000 0,04259718 0,06892322 ! limbic system development GO:0021761 36 17 0,000 0,04259718 0,0688769 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04259718 0,06883064 ! adult walking behavior GO:0007628 33 17 0,000 0,04259718 0,06878445 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04259718 0,06873831 ! heart looping GO:0001947 30 17 0,000 0,04259718 0,06869224 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04259718 0,06864623 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04259718 0,06860028 ! myoblast differentiation GO:0045445 45 17 0,000 0,04259718 0,0685544 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04259718 0,06850857 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04259718 0,06846281 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04259718 0,06841711 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04259718 0,06837146 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04259718 0,06832588 ! glycine metabolic process GO:0006544 28 17 0,000 0,04259718 0,06828036 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,04259718 0,0682349 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04259718 0,0681895 ! NAD metabolic process GO:0019674 29 17 0,000 0,04259718 0,06814416 ! membrane budding GO:0006900 37 17 0,000 0,04259718 0,06809889 ! DNA integration GO:0015074 29 17 0,000 0,04259718 0,06805367 ! regulation of protein binding GO:0043393 33 17 0,000 0,04259718 0,06800851 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04259718 0,06796341 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04259718 0,06791837 ! genitalia development GO:0048806 30 17 0,000 0,04259718 0,06787339 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04259718 0,06782847 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04259718 0,06778361 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04259718 0,06773881 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04259718 0,06769407 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04259718 0,06764939 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04259718 0,06760477 ! steroid catabolic process GO:0006706 31 17 0,000 0,04259718 0,0675602 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04259718 0,06751569 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04259718 0,06747125 ! gas transport GO:0015669 25 17 0,000 0,04259718 0,06742686 ! organic cation transport GO:0015695 31 17 0,000 0,04259718 0,06738253 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04259718 0,06733825 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04259718 0,06729404 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04259718 0,06724988 ! microspike assembly GO:0030035 36 17 0,000 0,04259718 0,06720579 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04259718 0,06716175 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04259718 0,06711776 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04504635 0,07093032 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04504635 0,07088393 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04504635 0,0708376 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04504635 0,07079133 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04504635 0,07074512 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04504635 0,07069897 ! memory GO:0007613 31 18 0,000 0,04504635 0,07065289 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04504635 0,07060686 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04504635 0,07056089 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04504635 0,07051498 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04504635 0,07046913 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04504635 0,07042334 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04504635 0,07037761 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04504635 0,07033194 ! response to retinoic acid GO:0032526 26 18 0,000 0,04504635 0,07028633 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04504635 0,07024078 ! response to fungus GO:0009620 21 18 0,000 0,04504635 0,07019529 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04504635 0,07014986 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04504635 0,07010448 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04504635 0,07005916 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04504635 0,07001391 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04504635 0,06996871 ! vitamin transport GO:0051180 27 18 0,000 0,04504635 0,06992357 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04504635 0,06987848 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04504635 0,06983346 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04504635 0,06978849 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04504635 0,06974358 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,04504635 0,06969873 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04504635 0,06965394 ! nerve development GO:0021675 28 18 0,000 0,04504635 0,0696092 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04504635 0,06956452 ! protein secretion GO:0009306 39 19 0,000 0,04748934 0,07329015 ! positive regulation of translation GO:0045727 30 19 0,000 0,04748934 0,07324317 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04748934 0,07319625 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04748934 0,07314939 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04748934 0,07310259 ! skin development GO:0043588 36 19 0,000 0,04748934 0,07305585 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04748934 0,07300917 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04748934 0,07296255 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04748934 0,07291599 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04748934 0,07286948 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04748934 0,07282304 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04748934 0,07277666 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04748934 0,07273033 ! cerebral cortex development GO:0021987 36 19 0,000 0,04748934 0,07268407 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04748934 0,07263786 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04748934 0,07259171 ! heme metabolic process GO:0042168 36 19 0,000 0,04748934 0,07254562 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04748934 0,07249959 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04748934 0,07245361 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04748934 0,0724077 ! peptide cross-linking GO:0018149 37 19 0,000 0,04748934 0,07236184 ! protein export from nucleus GO:0006611 36 19 0,000 0,04748934 0,07231604 ! heart process GO:0003015 30 19 0,000 0,04748934 0,0722703 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04748934 0,07222462 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04748934 0,072179 ! cellular pigmentation GO:0033059 36 19 0,000 0,04748934 0,07213343 ! G1 phase GO:0051318 40 19 0,000 0,04748934 0,07208792 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04748934 0,07204247 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04748934 0,07199707 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04748934 0,07195173 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04748934 0,07190645 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04748934 0,07186123 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04748934 0,07181606 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04748934 0,07177095 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04748934 0,0717259 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04748934 0,0716809 ! cilium assembly GO:0042384 37 19 0,000 0,04748934 0,07163596 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04748934 0,07159107 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04992616 0,07521749 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04992616 0,07517042 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04992616 0,07512341 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04992616 0,07507646 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04992616 0,07502956 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04992616 0,07498273 ! response to vitamin GO:0033273 31 20 0,000 0,04992616 0,07493595 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04992616 0,07488923 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04992616 0,07484257 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04992616 0,07479597 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04992616 0,07474943 ! response to alkaloid GO:0043279 38 20 0,000 0,04992616 0,07470294 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04992616 0,07465652 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04992616 0,07461014 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04992616 0,07456383 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04992616 0,07451758 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04992616 0,07447138 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04992616 0,07442524 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04992616 0,07437915 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,04992616 0,07433313 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04992616 0,07428716 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04992616 0,07424124 ! body fluid secretion GO:0007589 31 20 0,000 0,04992616 0,07419539 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04992616 0,07414959 ! peptide secretion GO:0002790 35 20 0,000 0,04992616 0,07410384 ! stem cell differentiation GO:0048863 53 20 0,000 0,04992616 0,07405816 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04992616 0,07401253 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04992616 0,07396695 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04992616 0,07392144 ! sensory perception of pain GO:0019233 30 20 0,000 0,04992616 0,07387597 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04992616 0,07383057 ! diencephalon development GO:0021536 34 20 0,000 0,04992616 0,07378522 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04992616 0,07373992 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04992616 0,07369468 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04992616 0,0736495 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04992616 0,07360437 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04992616 0,0735593 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04992616 0,07351428 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04992616 0,07346932 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04992616 0,07342441 ! regulation of glucose import GO:0046324 29 20 0,000 0,04992616 0,07337956 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04992616 0,07333476 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04992616 0,07329001 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04992616 0,07324532 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04992616 0,07320069 ! negative regulation of translation GO:0017148 29 20 0,000 0,04992616 0,07315611 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04992616 0,07311158 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04992616 0,07306711 ! regulation of cell killing GO:0031341 42 21 0,000 0,05235682 0,07657782 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05235682 0,07653129 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05235682 0,07648483 ! hormone secretion GO:0046879 38 21 0,000 0,05235682 0,07643842 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05235682 0,07639206 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05235682 0,07634576 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05235682 0,07629952 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05235682 0,07625334 ! axis specification GO:0009798 38 21 0,000 0,05235682 0,0762072 ! ovarian follicle development GO:0001541 35 21 0,000 0,05235682 0,07616113 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05235682 0,07611511 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05235682 0,07606915 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05235682 0,07602324 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05235682 0,07597739 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05235682 0,07593159 ! cell aging GO:0007569 44 21 0,000 0,05235682 0,07588585 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05235682 0,07584016 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05235682 0,07579453 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05235682 0,07574895 ! cytolysis GO:0019835 24 21 0,000 0,05235682 0,07570343 ! vasodilation GO:0042311 39 21 0,000 0,05235682 0,07565796 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05235682 0,07561255 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05235682 0,07556719 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05235682 0,07552189 ! oogenesis GO:0048477 36 21 0,000 0,05235682 0,07547664 ! DNA modification GO:0006304 34 21 0,000 0,05235682 0,07543144 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05235682 0,0753863 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05235682 0,07534121 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05235682 0,07529618 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05235682 0,0752512 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05235682 0,07520627 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05235682 0,0751614 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05235682 0,07511658 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05235682 0,07507182 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05235682 0,07502711 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05235682 0,07498245 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05235682 0,07493784 ! collagen catabolic process GO:0030574 28 21 0,000 0,05235682 0,07489329 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05235682 0,07484879 ! gut development GO:0048565 39 21 0,000 0,05235682 0,07480434 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05478135 0,07822191 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05478135 0,07817552 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05478135 0,07812918 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05478135 0,07808289 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05478135 0,07803666 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05478135 0,07799048 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05478135 0,07794436 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05478135 0,0778983 ! regeneration GO:0031099 41 22 0,000 0,05478135 0,07785228 ! keratinization GO:0031424 28 22 0,000 0,05478135 0,07780633 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05478135 0,07776042 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05478135 0,07771457 ! sensory perception of taste GO:0050909 28 22 0,000 0,05478135 0,07766878 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,05478135 0,07762304 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05478135 0,07757735 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05478135 0,07753172 ! vacuolar transport GO:0007034 36 22 0,000 0,05478135 0,07748614 ! lysosome organization GO:0007040 41 22 0,000 0,05478135 0,07744061 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05478135 0,07739514 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05478135 0,07734972 ! fucose metabolic process GO:0006004 39 22 0,000 0,05478135 0,07730435 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05478135 0,07725904 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05478135 0,07721378 ! ureteric bud development GO:0001657 43 22 0,000 0,05478135 0,07716857 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05478135 0,07712342 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05478135 0,07707831 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05478135 0,07703327 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05478135 0,07698827 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05478135 0,07694333 ! sarcomere organization GO:0045214 30 22 0,000 0,05478135 0,07689844 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,05478135 0,0768536 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05478135 0,07680881 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05478135 0,07676408 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05478135 0,07671939 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05478135 0,07667476 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05478135 0,07663019 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,05719975 0,07996664 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05719975 0,07992021 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,05719975 0,07987382 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05719975 0,07982749 ! gluconeogenesis GO:0006094 33 23 0,000 0,05719975 0,07978121 ! viral genome replication GO:0019079 41 23 0,000 0,05719975 0,07973499 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05719975 0,07968882 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05719975 0,07964271 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05719975 0,07959664 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05719975 0,07955063 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05719975 0,07950468 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05719975 0,07945877 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,05719975 0,07941292 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05719975 0,07936713 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05719975 0,07932138 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05719975 0,07927569 ! peroxisome organization GO:0007031 37 23 0,000 0,05719975 0,07923005 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05719975 0,07918446 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05719975 0,07913893 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05719975 0,07909345 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05719975 0,07904802 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,05719975 0,07900264 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,05719975 0,07895731 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05719975 0,07891204 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05719975 0,07886682 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05719975 0,07882165 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05719975 0,07877653 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05719975 0,07873146 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05719975 0,07868645 ! fatty acid transport GO:0015908 44 23 0,000 0,05719975 0,07864148 ! platelet activation GO:0030168 37 23 0,000 0,05719975 0,07859657 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05719975 0,07855171 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05719975 0,0785069 ! hormone transport GO:0009914 40 23 0,000 0,05719975 0,07846214 ! cell-cell recognition GO:0009988 25 23 0,000 0,05719975 0,07841743 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05719975 0,07837278 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05719975 0,07832817 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05719975 0,07828362 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05719975 0,07823911 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05961204 0,08149237 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05961204 0,0814461 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05961204 0,08139987 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05961204 0,0813537 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05961204 0,08130758 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05961204 0,08126152 ! vesicle docking GO:0048278 47 24 0,000 0,05961204 0,0812155 ! spinal cord development GO:0021510 47 24 0,000 0,05961204 0,08116954 ! vacuole organization GO:0007033 43 24 0,000 0,05961204 0,08112363 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05961204 0,08107777 ! digestive system process GO:0022600 39 24 0,000 0,05961204 0,08103197 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05961204 0,08098621 ! regulation of behavior GO:0050795 43 24 0,000 0,05961204 0,08094051 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05961204 0,08089486 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05961204 0,08084926 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05961204 0,08080371 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05961204 0,08075821 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05961204 0,08071276 ! pallium development GO:0021543 49 24 0,000 0,05961204 0,08066737 ! pentose metabolic process GO:0019321 35 24 0,000 0,05961204 0,08062202 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,05961204 0,08057673 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05961204 0,08053149 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05961204 0,0804863 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05961204 0,08044115 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05961204 0,08039606 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05961204 0,08035102 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05961204 0,08030604 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05961204 0,0802611 ! regulation of amine transport GO:0051952 40 24 0,000 0,05961204 0,08021621 ! protein tetramerization GO:0051262 52 24 0,000 0,05961204 0,08017137 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06201825 0,08336084 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,06201825 0,0833143 ! myelination GO:0042552 45 25 0,000 0,06201825 0,0832678 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06201825 0,08322136 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06201825 0,08317497 ! phototransduction GO:0007602 33 25 0,000 0,06201825 0,08312864 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06201825 0,08308235 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06201825 0,08303612 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,06201825 0,08298994 ! sperm motility GO:0030317 31 25 0,000 0,06201825 0,0829438 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06201825 0,08289772 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,06201825 0,0828517 ! chromosome condensation GO:0030261 45 25 0,000 0,06201825 0,08280572 ! response to starvation GO:0042594 42 25 0,000 0,06201825 0,08275979 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06201825 0,08271392 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,06201825 0,08266809 ! neural crest cell development GO:0014032 54 25 0,000 0,06201825 0,08262232 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06201825 0,08257659 ! negative regulation of cell development GO:0010721 73 25 0,000 0,06201825 0,08253092 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06201825 0,0824853 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06201825 0,08243973 ! interaction with host GO:0051701 62 25 0,000 0,06201825 0,0823942 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06201825 0,08234873 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06201825 0,08230331 ! somitogenesis GO:0001756 43 25 0,000 0,06201825 0,08225794 ! immunoglobulin production GO:0002377 55 25 0,000 0,06201825 0,08221262 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06201825 0,08216735 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06201825 0,08212213 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06201825 0,08207695 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,06201825 0,08203183 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06201825 0,08198676 ! telomere organization GO:0032200 43 25 0,000 0,06201825 0,08194174 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06201825 0,08189676 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06201825 0,08185184 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06441837 0,08497292 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06441837 0,08492636 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06441837 0,08487985 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06441837 0,08483339 ! initiation of viral infection GO:0019059 57 26 0,000 0,06441837 0,08478698 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06441837 0,08474063 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06441837 0,08469432 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06441837 0,08464806 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06441837 0,08460186 ! molting cycle process GO:0022404 50 26 0,000 0,06441837 0,0845557 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06441837 0,0845096 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06441837 0,08446355 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06441837 0,08441754 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06441837 0,08437159 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,06441837 0,08432568 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06441837 0,08427983 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,06441837 0,08423403 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,06441837 0,08418827 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06441837 0,08414257 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06441837 0,08409691 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06441837 0,08405131 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06441837 0,08400575 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06441837 0,08396024 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06441837 0,08391478 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06441837 0,08386938 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06441837 0,08382402 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06441837 0,08377871 ! blastocyst development GO:0001824 49 26 0,000 0,06441837 0,08373345 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06441837 0,08368823 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06441837 0,08364307 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06441837 0,08359795 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,06681244 0,08665807 ! neuron fate commitment GO:0048663 48 27 0,000 0,06681244 0,08661138 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06681244 0,08656474 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06681244 0,08651815 ! iron ion transport GO:0006826 59 27 0,000 0,06681244 0,08647161 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,06681244 0,08642512 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06681244 0,08637868 ! protein amino acid acylation GO:0043543 55 27 0,000 0,06681244 0,08633229 ! superoxide metabolic process GO:0006801 38 27 0,000 0,06681244 0,08628595 ! fat cell differentiation GO:0045444 50 27 0,000 0,06681244 0,08623966 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06681244 0,08619342 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,06681244 0,08614723 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06681244 0,08610108 ! autophagy GO:0006914 41 27 0,000 0,06681244 0,08605499 ! male gonad development GO:0008584 44 27 0,000 0,06681244 0,08600895 ! response to toxin GO:0009636 47 27 0,000 0,06681244 0,08596295 ! primary neural tube formation GO:0014020 51 27 0,000 0,06681244 0,08591701 ! base-excision repair GO:0006284 41 27 0,000 0,06681244 0,08587111 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06681244 0,08582527 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06681244 0,08577947 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06681244 0,08573372 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06681244 0,08568802 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06681244 0,08564237 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06681244 0,08559677 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06681244 0,08555121 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06920046 0,08856186 ! circadian rhythm GO:0007623 50 28 0,000 0,06920046 0,08851478 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06920046 0,08846774 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06920046 0,08842076 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06920046 0,08837383 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06920046 0,08832695 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,06920046 0,08828011 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06920046 0,08823333 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06920046 0,0881866 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06920046 0,08813991 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06920046 0,08809328 ! synaptogenesis GO:0007416 42 28 0,000 0,06920046 0,08804669 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,06920046 0,08800016 ! lipid oxidation GO:0034440 43 28 0,000 0,06920046 0,08795367 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06920046 0,08790723 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06920046 0,08786084 ! translational initiation GO:0006413 65 29 0,000 0,07158244 0,09083721 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07158244 0,09078933 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07158244 0,09074149 ! regulation of pH GO:0006885 43 29 0,000 0,07158244 0,09069371 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07158244 0,09064598 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07158244 0,09059829 ! catechol metabolic process GO:0009712 54 29 0,000 0,07158244 0,09055066 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07158244 0,09050308 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07158244 0,09045554 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07158244 0,09040806 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07158244 0,09036063 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07158244 0,09031324 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07158244 0,09026591 ! cell fate determination GO:0001709 60 29 0,000 0,07158244 0,09021862 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07158244 0,09017139 ! detection of light stimulus GO:0009583 38 29 0,000 0,07158244 0,0901242 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,07158244 0,09007707 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07158244 0,09002998 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07158244 0,08998294 ! tissue homeostasis GO:0001894 48 29 0,000 0,07158244 0,08993595 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07158244 0,08988901 ! phenol metabolic process GO:0018958 55 30 0,000 0,07395841 0,09282417 ! zinc ion transport GO:0006829 45 30 0,000 0,07395841 0,09277577 ! membrane docking GO:0022406 61 30 0,000 0,07395841 0,09272743 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07395841 0,09267913 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07395841 0,09263089 ! acute-phase response GO:0006953 49 30 0,000 0,07395841 0,09258269 ! myofibril assembly GO:0030239 47 30 0,000 0,07395841 0,09253455 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07395841 0,09248645 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07395841 0,09243841 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07395841 0,09239041 ! phospholipid transport GO:0015914 51 30 0,000 0,07395841 0,09234247 ! ensheathment of neurons GO:0007272 57 30 0,000 0,07395841 0,09229457 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07395841 0,09224673 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07395841 0,09219893 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07395841 0,09215118 ! eye morphogenesis GO:0048592 60 30 0,000 0,07395841 0,09210349 ! response to heat GO:0009408 50 30 0,000 0,07395841 0,09205584 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07632838 0,09495661 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07632838 0,09490753 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07632838 0,09485851 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07632838 0,09480954 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,07632838 0,09476062 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07632838 0,09471175 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07632838 0,09466293 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07632838 0,09461415 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,07632838 0,09456543 ! ovulation cycle process GO:0022602 49 31 0,000 0,07632838 0,09451677 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07632838 0,09446815 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07632838 0,09441958 ! peptide transport GO:0015833 55 31 0,000 0,07632838 0,09437106 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,07632838 0,09432259 ! iron ion homeostasis GO:0055072 54 31 0,000 0,07632838 0,09427417 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07632838 0,0942258 ! natural killer cell activation GO:0030101 45 31 0,000 0,07632838 0,09417747 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,07632838 0,0941292 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07632838 0,09408098 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07632838 0,09403281 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07632838 0,09398469 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07869236 0,09684594 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07869236 0,09679643 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07869236 0,09674697 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07869236 0,09669755 ! cholesterol transport GO:0030301 56 32 0,000 0,07869236 0,09664819 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07869236 0,09659888 ! spliceosome assembly GO:0000245 67 32 0,000 0,07869236 0,09654962 ! metanephros development GO:0001656 74 32 0,000 0,07869236 0,09650041 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07869236 0,09645125 ! response to ionizing radiation GO:0010212 65 32 0,000 0,07869236 0,09640214 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07869236 0,09635308 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07869236 0,09630408 ! muscle cell development GO:0055001 49 32 0,000 0,07869236 0,09625512 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07869236 0,09620621 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07869236 0,09615734 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07869236 0,09610853 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07869236 0,09605977 ! ovulation cycle GO:0042698 51 32 0,000 0,07869236 0,09601106 ! peripheral nervous system development GO:0007422 64 32 0,000 0,07869236 0,0959624 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07869236 0,09591379 ! hindbrain development GO:0030902 61 32 0,000 0,07869236 0,09586522 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07869236 0,09581671 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07869236 0,09576824 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,07869236 0,09571982 ! gene silencing GO:0016458 65 32 0,000 0,07869236 0,09567146 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,08105037 0,09848847 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,08105037 0,09843876 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08105037 0,09838909 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08105037 0,09833948 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08105037 0,09828991 ! sterol transport GO:0015918 57 33 0,000 0,08105037 0,09824039 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,08105037 0,09819093 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08105037 0,09814151 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08105037 0,09809214 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08340242 0,10088799 ! glial cell differentiation GO:0010001 63 34 0,000 0,08340242 0,10083729 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08340242 0,10078665 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08340242 0,10073605 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08340242 0,10068551 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08340242 0,10063501 ! mismatch repair GO:0006298 46 34 0,000 0,08340242 0,10058457 ! spermatid development GO:0007286 63 34 0,000 0,08340242 0,10053418 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08340242 0,10048383 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08340242 0,10043354 ! placenta development GO:0001890 53 34 0,000 0,08340242 0,1003833 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,08340242 0,10033311 ! regulation of muscle development GO:0048634 70 35 0,000 0,08574853 0,10310393 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,08574853 0,10305243 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08574853 0,10300098 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,08574853 0,10294958 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08574853 0,10289823 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,08574853 0,10284694 ! odontogenesis GO:0042476 66 35 0,000 0,08574853 0,10279569 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08574853 0,1027445 ! female gonad development GO:0008585 58 35 0,000 0,08574853 0,10269336 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08574853 0,10264227 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,08574853 0,10259123 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,08574853 0,10254024 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,08574853 0,1024893 ! cytokine production GO:0001816 59 35 0,000 0,08574853 0,10243841 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,08574853 0,10238757 ! neural tube formation GO:0001841 67 35 0,000 0,08574853 0,10233678 ! vesicle localization GO:0051648 64 35 0,000 0,08574853 0,10228605 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08808871 0,10502549 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08808871 0,10497347 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08808871 0,1049215 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08808871 0,10486959 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08808871 0,10481772 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,08808871 0,10476591 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08808871 0,10471415 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08808871 0,10466244 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,08808871 0,10461078 ! aerobic respiration GO:0009060 55 36 0,000 0,08808871 0,10455917 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,08808871 0,10450761 ! embryonic organ development GO:0048568 57 36 0,000 0,08808871 0,1044561 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08808871 0,10440465 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09042298 0,10711851 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,09042298 0,10706579 ! sister chromatid segregation GO:0000819 58 37 0,000 0,09042298 0,10701313 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09042298 0,10696052 ! organic anion transport GO:0015711 68 37 0,000 0,09042298 0,10690795 ! tissue remodeling GO:0048771 76 37 0,000 0,09042298 0,10685545 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,09042298 0,10680299 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09042298 0,10675058 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,09042298 0,10669823 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09042298 0,10664593 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,09042298 0,10659367 ! spermatid differentiation GO:0048515 66 37 0,000 0,09042298 0,10654147 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,09042298 0,10648932 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,09275135 0,10917796 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,09275135 0,10912457 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,09275135 0,10907124 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,09275135 0,10901795 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,09275135 0,10896472 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,09275135 0,10891154 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,09275135 0,10885842 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,09275135 0,10880534 ! lipid homeostasis GO:0055088 67 38 0,000 0,09275135 0,10875232 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,09275135 0,10869934 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,09275135 0,10864642 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,09275135 0,10859355 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,09275135 0,10854073 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,09275135 0,10848797 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,09275135 0,10843525 ! glucan metabolic process GO:0044042 62 38 0,000 0,09275135 0,10838259 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09507384 0,11104255 ! mammary gland development GO:0030879 86 39 0,000 0,09507384 0,11098868 ! ear morphogenesis GO:0042471 60 39 0,000 0,09507384 0,11093485 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09507384 0,11088108 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09507384 0,11082735 ! segmentation GO:0035282 67 39 0,000 0,09507384 0,11077368 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09507384 0,11072007 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09507384 0,1106665 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,09507384 0,11061299 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09507384 0,11055953 ! RNA modification GO:0009451 57 39 0,000 0,09507384 0,11050612 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09507384 0,11045276 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09739046 0,1130895 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09739046 0,11303495 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09739046 0,11298045 ! feeding behavior GO:0007631 59 40 0,000 0,09739046 0,112926 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09739046 0,1128716 ! mesenchymal cell development GO:0014031 87 40 0,000 0,09739046 0,11281726 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09739046 0,11276297 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09970123 0,11538295 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09970123 0,11532748 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09970123 0,11527206 ! gliogenesis GO:0042063 88 41 0,000 0,09970123 0,11521669 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,09970123 0,11516138 ! T cell differentiation GO:0030217 81 41 0,000 0,09970123 0,11510612 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,09970123 0,11505091 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,09970123 0,11499576 ! female gamete generation GO:0007292 61 41 0,000 0,09970123 0,11494066 ! polyol metabolic process GO:0019751 66 41 0,000 0,09970123 0,11488561 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,09970123 0,11483061 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,10200616 0,1174291 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,10200616 0,11737294 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,10200616 0,11731683 ! regulation of tube size GO:0035150 71 42 0,000 0,10200616 0,11726078 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,10200616 0,11720478 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,10200616 0,11714884 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,10200616 0,11709294 ! neuron migration GO:0001764 79 42 0,000 0,10200616 0,11703711 ! regulation of protein secretion GO:0050708 71 42 0,000 0,10200616 0,11698132 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10430526 0,11956096 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10430526 0,11950402 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10430526 0,11944715 ! glucose transport GO:0015758 65 43 0,000 0,10430526 0,11939032 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10430526 0,11933355 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,10430526 0,11927683 ! neural tube development GO:0021915 77 43 0,000 0,10430526 0,11922017 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,10430526 0,11916356 ! striated muscle contraction GO:0006941 77 43 0,000 0,10430526 0,119107 ! phagocytosis GO:0006909 90 43 0,000 0,10430526 0,1190505 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10430526 0,11899405 ! hexose transport GO:0008645 67 44 0,000 0,10659855 0,12155266 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10659855 0,12149508 ! male sex differentiation GO:0046661 76 44 0,000 0,10659855 0,12143755 ! double-strand break repair GO:0006302 81 44 0,000 0,10659855 0,12138008 ! biopolymer methylation GO:0043414 84 44 0,000 0,10659855 0,12132267 ! B cell differentiation GO:0030183 107 44 0,000 0,10659855 0,1212653 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10659855 0,12120799 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10659855 0,12115074 ! developmental growth GO:0048589 82 44 0,000 0,10659855 0,12109354 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,10888605 0,12363371 ! glycolysis GO:0006096 65 45 0,000 0,10888605 0,12357539 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,10888605 0,12351713 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,10888605 0,12345892 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,10888605 0,12340077 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,10888605 0,12334267 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,10888605 0,12328463 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,10888605 0,12322664 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,10888605 0,1231687 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,10888605 0,12311082 ! cell growth GO:0016049 84 45 0,000 0,10888605 0,123053 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,11116777 0,1255726 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,11116777 0,12551368 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,11116777 0,1254548 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11116777 0,12539599 ! response to insulin stimulus GO:0032868 95 46 0,000 0,11116777 0,12533723 ! positive regulation of defense response GO:0031349 76 47 0,000 0,11344371 0,12784336 ! response to calcium ion GO:0051592 81 47 0,000 0,11344371 0,12778351 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,11344371 0,12772371 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,11344371 0,12766397 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,11344371 0,12760429 ! JNK cascade GO:0007254 91 47 0,000 0,11344371 0,12754466 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,11344371 0,12748509 ! methylation GO:0032259 90 47 0,000 0,11344371 0,12742557 ! protein homooligomerization GO:0051260 76 47 0,000 0,11344371 0,12736611 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,11571391 0,12985433 ! mitochondrial transport GO:0006839 82 48 0,000 0,11571391 0,12979379 ! Notch signaling pathway GO:0007219 96 48 0,000 0,11571391 0,12973331 ! cellular component disassembly GO:0022411 86 48 0,000 0,11571391 0,12967288 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11571391 0,12961251 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11571391 0,1295522 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11571391 0,12949194 ! activation of caspase activity GO:0006919 84 48 0,000 0,11571391 0,12943174 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,11571391 0,1293716 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,11571391 0,12931151 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11797837 0,13178086 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,11797837 0,1317197 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,11797837 0,13165861 ! regulation of ion transport GO:0043269 77 49 0,000 0,11797837 0,13159757 ! peptide metabolic process GO:0006518 76 49 0,000 0,11797837 0,13153659 ! response to temperature stimulus GO:0009266 76 49 0,000 0,11797837 0,13147567 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11797837 0,1314148 ! endocrine system development GO:0035270 104 49 0,000 0,11797837 0,13135399 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11797837 0,13129323 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,11797837 0,13123253 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11797837 0,13117189 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,11797837 0,1311113 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,12023711 0,13355978 ! regulation of ossification GO:0030278 117 50 0,000 0,12023711 0,13349815 ! inner ear development GO:0048839 79 50 0,000 0,12023711 0,13343657 ! histone modification GO:0016570 91 50 0,000 0,12023711 0,13337505 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,12023711 0,13331359 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,12023711 0,13325218 ! positive regulation of binding GO:0051099 78 51 0,000 0,12249013 0,13568658 ! viral infectious cycle GO:0019058 99 51 0,000 0,12249013 0,13562414 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,12249013 0,13556176 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,12249013 0,13549943 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,12249013 0,13543716 ! excretion GO:0007588 83 51 0,000 0,12249013 0,13537495 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,12249013 0,13531279 ! chromatin remodeling GO:0006338 109 51 0,000 0,12249013 0,13525069 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,12249013 0,13518865 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,12249013 0,13512667 ! vesicle organization GO:0016050 107 51 0,000 0,12249013 0,13506474 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,12249013 0,13500287 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,12249013 0,13494105 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,12473746 0,13735393 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,12473746 0,1372911 ! positive regulation of growth GO:0045927 90 52 0,000 0,12473746 0,13722832 ! covalent chromatin modification GO:0016569 101 52 0,000 0,12473746 0,1371656 ! amino acid activation GO:0043038 92 52 0,000 0,12473746 0,13710294 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,12473746 0,13704034 ! synapse organization GO:0050808 85 52 0,000 0,12473746 0,13697779 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,12697912 0,1393758 ! RNA catabolic process GO:0006401 93 53 0,000 0,12697912 0,13931224 ! regulation of translational initiation GO:0006446 82 53 0,000 0,12697912 0,13924875 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,12697912 0,13918531 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,12697912 0,13912193 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,12697912 0,1390586 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,12697912 0,13899534 ! response to UV GO:0009411 104 53 0,000 0,12697912 0,13893213 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,1292151 0,14131433 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,1292151 0,14125013 ! cell recognition GO:0008037 85 54 0,000 0,1292151 0,14118598 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,1292151 0,14112189 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,1292151 0,14105786 ! chloride transport GO:0006821 90 55 0,000 0,13144543 0,14342753 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,13144543 0,14336251 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,13144543 0,14329755 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,13144543 0,14323266 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,13144543 0,14316782 ! aging GO:0007568 103 55 0,000 0,13144543 0,14310303 ! heart morphogenesis GO:0003007 97 55 0,000 0,13144543 0,14303831 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,13144543 0,14297365 ! RNA elongation GO:0006354 79 55 0,000 0,13144543 0,14290904 ! nuclear export GO:0051168 97 55 0,000 0,13144543 0,14284449 ! regulation of actin filament length GO:0030832 105 56 0,000 0,13367012 0,14519653 ! sensory perception of smell GO:0007608 80 56 0,000 0,13367012 0,14513101 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,13367012 0,14506555 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,13367012 0,14500014 ! regulation of DNA replication GO:0006275 101 56 0,000 0,13367012 0,1449348 ! proton transport GO:0015992 94 56 0,000 0,13367012 0,14486951 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,13367012 0,14480428 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,13588919 0,14714194 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,13588919 0,14707575 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,13588919 0,14700962 ! lipid modification GO:0030258 97 57 0,000 0,13588919 0,14694355 ! hydrogen transport GO:0006818 97 58 0,000 0,13810265 0,14926998 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,13810265 0,14920295 ! positive regulation of secretion GO:0051047 95 59 0,000 0,14031051 0,15152023 ! regulation of cellular component size GO:0032535 109 59 0,000 0,14031051 0,15145226 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,14031051 0,15138434 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,14031051 0,15131649 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,14031051 0,15124869 ! DNA catabolic process GO:0006308 86 59 0,000 0,14031051 0,15118096 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,14251279 0,15348512 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,14251279 0,15341645 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,14251279 0,15334784 ! regulation of heart contraction GO:0008016 110 60 0,000 0,14251279 0,15327929 ! camera-type eye development GO:0043010 116 60 0,000 0,14251279 0,1532108 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,14251279 0,15314237 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,14251279 0,153074 ! kidney development GO:0001822 122 60 0,000 0,14251279 0,1530057 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1447095 0,15529485 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,1447095 0,15522561 ! tRNA processing GO:0008033 89 61 0,000 0,1447095 0,15515644 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1447095 0,15508733 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,1447095 0,15501828 ! ear development GO:0043583 103 62 0,000 0,14690065 0,15729549 ! viral reproductive process GO:0022415 126 62 0,000 0,14690065 0,15722552 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,14690065 0,15715561 ! gonad development GO:0008406 98 62 0,000 0,14690065 0,15708576 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,14690065 0,15701598 ! regulation of mitosis GO:0007088 105 63 0,000 0,14908627 0,15928133 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,14908627 0,15921063 ! detection of external stimulus GO:0009581 91 63 0,000 0,14908627 0,15914 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,14908627 0,15906943 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,14908627 0,15899892 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,15126636 0,16125248 ! cell redox homeostasis GO:0045454 102 64 0,000 0,15126636 0,16118107 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,15126636 0,16110972 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,15126636 0,16103843 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,15126636 0,1609672 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,15344093 0,16320905 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,15344093 0,16313693 ! germ cell development GO:0007281 118 65 0,000 0,15344093 0,16306487 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,15561 0,16529699 ! extracellular matrix organization GO:0030198 133 66 0,000 0,15561 0,16522404 ! secondary metabolic process GO:0019748 116 66 0,000 0,15561 0,16515116 ! cell projection assembly GO:0030031 120 66 0,000 0,15561 0,16507834 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15777359 0,16729981 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,15777359 0,16722611 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,15777359 0,16715247 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,15777359 0,1670789 ! activation of MAPK activity GO:0000187 115 67 0,000 0,15777359 0,1670054 ! chromosome segregation GO:0007059 113 67 0,000 0,15777359 0,16693196 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15777359 0,16685858 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,15777359 0,16678527 ! hexose catabolic process GO:0019320 104 67 0,000 0,15777359 0,16671202 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,15777359 0,16663884 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15777359 0,16656572 ! adaptive immune response GO:0002250 119 67 0,000 0,15777359 0,16649266 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,15777359 0,16641967 ! amino acid transport GO:0006865 125 68 0,000 0,15993171 0,16862213 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,15993171 0,16854827 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,15993171 0,16847447 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,15993171 0,16840074 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,15993171 0,16832708 ! viral reproduction GO:0016032 134 68 0,000 0,15993171 0,16825348 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,15993171 0,16817994 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,15993171 0,16810647 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,16208437 0,17029476 ! negative regulation of cell size GO:0045792 134 69 0,000 0,16208437 0,17022043 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,16208437 0,17014616 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,16208437 0,17007196 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,16208437 0,16999782 ! antigen processing and presentation GO:0019882 104 69 0,000 0,16208437 0,16992375 ! amine catabolic process GO:0009310 117 71 0,000 0,16637337 0,17434422 ! humoral immune response GO:0006959 109 71 0,000 0,16637337 0,17426832 ! B cell activation GO:0042113 160 71 0,000 0,16637337 0,17419248 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,16637337 0,17411671 ! regulation of immune effector process GO:0002697 137 71 0,000 0,16637337 0,17404101 ! acute inflammatory response GO:0002526 113 72 0,000 0,16850974 0,17619923 ! regulation of caspase activity GO:0043281 122 72 0,000 0,16850974 0,17612269 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,16850974 0,17604621 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,16850974 0,1759698 ! carbohydrate transport GO:0008643 110 72 0,000 0,16850974 0,17589346 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,16850974 0,17581718 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,16850974 0,17574097 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,16850974 0,17566483 ! regulation of blood pressure GO:0008217 125 73 0,000 0,1706407 0,17780923 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,1706407 0,17773226 ! axon guidance GO:0007411 139 73 0,000 0,1706407 0,17765535 ! fertilization GO:0009566 90 73 0,000 0,1706407 0,17757851 ! transition metal ion transport GO:0000041 126 74 0,000 0,17276627 0,17971277 ! neurotransmitter transport GO:0006836 123 74 0,000 0,17276627 0,17963511 ! exocytosis GO:0006887 133 74 0,000 0,17276627 0,17955751 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,17276627 0,17947998 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,17276627 0,17940252 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,17276627 0,17932513 ! eye development GO:0001654 143 74 0,000 0,17276627 0,1792478 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,17488646 0,18136932 ! rhythmic process GO:0048511 128 75 0,000 0,17488646 0,18129118 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,17488646 0,1812131 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,17700129 0,18332549 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,17700129 0,18324661 ! defense response to bacterium GO:0042742 89 76 0,000 0,17700129 0,18316779 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,17700129 0,18308904 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,17700129 0,18301036 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,17911077 0,18511191 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,17911077 0,18503243 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,17911077 0,18495301 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,17911077 0,18487367 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,18121492 0,1869653 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,18121492 0,18688517 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,18121492 0,18680509 ! protein oligomerization GO:0051259 139 78 0,000 0,18121492 0,18672509 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,18331374 0,18880687 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,18331374 0,18872608 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,18331374 0,18864536 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,18331374 0,18856471 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,18331374 0,18848412 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,18331374 0,18840361 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,18331374 0,18832316 ! response to metal ion GO:0010038 140 80 0,000 0,18540725 0,19039259 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,18540725 0,19031136 ! protein import into nucleus GO:0006606 158 80 0,000 0,18540725 0,19023021 ! inorganic anion transport GO:0015698 138 80 0,000 0,18540725 0,19014912 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,18749546 0,19220881 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,18749546 0,19212695 ! nuclear import GO:0051170 161 81 0,000 0,18749546 0,19204516 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,18749546 0,19196344 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,18957839 0,19401344 ! response to drug GO:0042493 143 82 0,000 0,18957839 0,19393095 ! response to nutrient GO:0007584 125 82 0,000 0,18957839 0,19384853 ! negative regulation of growth GO:0045926 155 84 0,000 0,19372845 0,19800792 ! regulation of ligase activity GO:0051340 142 84 0,000 0,19372845 0,19792384 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,19372845 0,19783983 ! response to unfolded protein GO:0006986 131 85 0,000 0,1957956 0,19986603 ! nucleosome assembly GO:0006334 122 85 0,000 0,1957956 0,19978126 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,1957956 0,19969658 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,1957956 0,19961196 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,19785753 0,20162864 ! response to inorganic substance GO:0010035 153 86 0,000 0,19785753 0,20154327 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,19785753 0,20145798 ! chromatin assembly GO:0031497 124 86 0,000 0,19785753 0,20137276 ! mitochondrion organization GO:0007005 148 86 0,000 0,19785753 0,20128762 ! alcohol catabolic process GO:0046164 130 86 0,000 0,19785753 0,20120254 ! amine transport GO:0015837 155 86 0,000 0,19785753 0,20111754 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,19991424 0,20312232 ! protein localization in nucleus GO:0034504 176 87 0,000 0,19991424 0,20303658 ! cellular respiration GO:0045333 135 88 0,000 0,20196574 0,20503357 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,20196574 0,2049471 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,20196574 0,20486069 ! cellular defense response GO:0006968 114 89 0,000 0,20401205 0,20684913 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,20401205 0,206762 ! ossification GO:0001503 188 90 0,000 0,20605318 0,20874271 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,20605318 0,20865486 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,20605318 0,20856708 ! bone development GO:0060348 189 91 0,000 0,20808914 0,21053931 ! sterol metabolic process GO:0016125 152 91 0,000 0,20808914 0,21045081 ! response to protein stimulus GO:0051789 149 91 0,000 0,20808914 0,21036239 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,20808914 0,21027404 ! regulation of defense response GO:0031347 149 92 0,000 0,21011995 0,21223703 ! nucleosome organization GO:0034728 138 92 0,000 0,21011995 0,21214797 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,21011995 0,21205898 ! vitamin metabolic process GO:0006766 139 92 0,000 0,21011995 0,21197007 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,21214562 0,21392388 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,21214562 0,21383426 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,21214562 0,21374471 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,21214562 0,21365524 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,21416617 0,21559992 ! female pregnancy GO:0007565 164 94 0,000 0,21416617 0,21550974 ! transcription initiation GO:0006352 153 94 0,000 0,21416617 0,21541965 ! regulation of T cell activation GO:0050863 158 94 0,000 0,21416617 0,21532963 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,2161816 0,21726521 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,2161816 0,2171745 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,21819192 0,21910257 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,21819192 0,21901117 ! detection of stimulus GO:0051606 151 96 0,000 0,21819192 0,21891984 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,22019716 0,22083967 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,22019716 0,22074765 ! response to virus GO:0009615 160 98 0,000 0,22219732 0,22266004 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,22219732 0,22256734 ! interphase GO:0051325 213 98 0,000 0,22219732 0,22247472 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,22219732 0,22238218 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,22419242 0,22428564 ! cell cycle arrest GO:0007050 213 100 0,000 0,22618246 0,22618246