pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6884-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glutamate signaling pathway GO:0007215 48 22 3,000 2,368E-07 5,784E-04 ! dopamine receptor signaling pathway GO:0007212 28 12 2,000 3,067E-06 3,746E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 2,000 6,309E-06 5,137E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 2,000 6,309E-06 3,853E-03 ! regulation of postsynaptic membrane potential GO:0060078 38 19 2,000 1,334E-05 6,518E-03 ! visual learning GO:0008542 38 19 2,000 1,334E-05 5,432E-03 ! actin filament bundle formation GO:0051017 47 20 2,000 1,567E-05 5,468E-03 ! visual behavior GO:0007632 46 23 2,000 2,421E-05 7,393E-03 ! response to ethanol GO:0045471 47 23 2,000 2,421E-05 6,572E-03 ! membrane depolarization GO:0051899 45 24 2,000 2,762E-05 6,748E-03 ! actin filament organization GO:0007015 167 72 3,000 3,033E-05 6,737E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 5,894E-05 0,01199944 GO:0032414|positive regulation of ion transmembrane transporter activity, ! forebrain neuron development GO:0021884 13 5 1,000 5,894E-05 0,01107641 ! metaphase GO:0051323 11 5 1,000 5,894E-05 0,01028523 ! regulation of sensory perception GO:0051931 8 5 1,000 5,894E-05 9,6E-03 GO:0051930|regulation of sensory perception of pain, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 1,000 5,894E-05 9E-03 ! regulation of membrane potential GO:0042391 179 94 3,000 8,631E-05 0,01240265 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 8,827E-05 0,01198032 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! early endosome to late endosome transport GO:0045022 16 6 1,000 8,827E-05 0,01134978 ! establishment of spindle localization GO:0051293 16 6 1,000 8,827E-05 0,01078229 GO:0051653|spindle localization, ! purine base biosynthetic process GO:0009113 17 6 1,000 8,827E-05 0,01026885 ! negative regulation of B cell activation GO:0050869 14 6 1,000 8,827E-05 9,802E-03 ! prostate gland development GO:0030850 14 7 1,000 1,234E-04 0,01310535 ! forebrain neuron differentiation GO:0021879 16 7 1,000 1,234E-04 0,01255929 ! neuron remodeling GO:0016322 16 7 1,000 1,234E-04 0,01205692 ! monocyte differentiation GO:0030224 16 7 1,000 1,234E-04 0,01159319 ! learning GO:0007612 82 40 2,000 1,311E-04 0,01185855 ! generation of neurons in the forebrain GO:0021872 18 8 1,000 1,642E-04 0,01433061 ! regulation of pigmentation during development GO:0048070 25 8 1,000 1,642E-04 0,01383646 ! receptor clustering GO:0043113 20 9 1,000 2,108E-04 0,01716935 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 1,000 2,108E-04 0,0166155 ! purine base metabolic process GO:0006144 25 9 1,000 2,108E-04 0,01609626 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 2,554E-04 0,01891065 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 1,000 2,631E-04 0,01890663 GO:0007520|myoblast fusion, ! nucleobase biosynthetic process GO:0046112 26 10 1,000 2,631E-04 0,01836644 ! epithelial cell development GO:0002064 21 10 1,000 2,631E-04 0,01785626 ! regulation of B cell differentiation GO:0045577 24 10 1,000 2,631E-04 0,01737366 ! syncytium formation GO:0006949 20 11 1,000 3,211E-04 0,02064275 ! cell maturation GO:0048469 107 55 2,000 3,389E-04 0,02122984 ! negative regulation of cell motion GO:0051271 142 55 2,000 3,389E-04 0,02069909 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 3,847E-04 0,02292222 ! focal adhesion formation GO:0048041 37 12 1,000 3,847E-04 0,02237645 ! establishment of cell polarity GO:0030010 21 12 1,000 3,847E-04 0,02185607 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 1,000 4,539E-04 0,02520269 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! membrane protein proteolysis GO:0033619 33 13 1,000 4,539E-04 0,02464263 GO:0006509|membrane protein ectodomain proteolysis, ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 4,539E-04 0,02410692 ! myotube differentiation GO:0014902 26 14 1,000 5,287E-04 0,02748254 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 2,000 6,327E-04 0,03220367 ! developmental maturation GO:0021700 128 69 2,000 6,603E-04 0,0329223 ! startle response GO:0001964 28 16 1,000 6,95E-04 0,03395797 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 6,95E-04 0,03329213 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 6,95E-04 0,03265189 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! embryonic digit morphogenesis GO:0042733 36 16 1,000 6,95E-04 0,03203582 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 6,95E-04 0,03144256 ! cAMP-mediated signaling GO:0019933 124 71 2,000 7,178E-04 0,03188344 ! signal complex assembly GO:0007172 47 17 1,000 7,864E-04 0,03430758 ! endothelial cell migration GO:0043542 31 17 1,000 7,864E-04 0,03370569 ! nucleobase metabolic process GO:0009112 43 17 1,000 7,864E-04 0,03312456 ! learning or memory GO:0007611 161 76 2,000 8,751E-04 0,03623688 ! glutamine metabolic process GO:0006541 29 18 1,000 8,833E-04 0,03596568 ! cell-substrate junction assembly GO:0007044 56 18 1,000 8,833E-04 0,03537608 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 8,833E-04 0,0348055 ! neuron maturation GO:0042551 46 19 1,000 9,857E-04 0,03822194 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 9,857E-04 0,03762472 ! pigmentation during development GO:0048066 42 19 1,000 9,857E-04 0,03704588 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 1,093E-03 0,04047398 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 1,093E-03 0,03986989 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 1,093E-03 0,03928357 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 1,13E-03 0,04000099 ! plasma membrane fusion GO:0045026 33 21 1,000 1,207E-03 0,04211112 ! actin filament-based movement GO:0030048 47 21 1,000 1,207E-03 0,041518 ! regulation of cyclase activity GO:0031279 168 85 2,000 1,21E-03 0,04106368 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 1,252E-03 0,04189128 ! regulation of lyase activity GO:0051339 169 86 2,000 1,252E-03 0,04132518 ! central nervous system neuron development GO:0021954 47 22 1,000 1,325E-03 0,04316539 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,325E-03 0,04259742 ! protein stabilization GO:0050821 41 22 1,000 1,325E-03 0,04204421 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,382E-03 0,04327676 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 1,473E-03 0,04554873 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! central nervous system neuron differentiation GO:0021953 51 24 1,000 1,578E-03 0,04819735 ! negative regulation of catabolic process GO:0009895 52 24 1,000 1,578E-03 0,04760232 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 1,666E-03 0,04964725 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 1,713E-03 0,05041468 ! regulation of transmembrane transport GO:0034762 39 25 1,000 1,713E-03 0,0498145 ! receptor metabolic process GO:0043112 53 25 1,000 1,713E-03 0,04922845 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 1,822E-03 0,05174339 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,853E-03 0,05202209 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 1,000 1,853E-03 0,05143093 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 1,998E-03 0,05483412 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 1,000 2,303E-03 0,06252269 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 2,464E-03 0,06614734 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 1,000 2,464E-03 0,06542835 ! cell junction assembly GO:0034329 85 31 1,000 2,63E-03 0,06907884 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 2,63E-03 0,06834396 ! spindle organization GO:0007051 50 32 1,000 2,801E-03 0,07201845 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 2,801E-03 0,07126825 ! mesoderm formation GO:0001707 73 32 1,000 2,801E-03 0,07053353 ! pigment biosynthetic process GO:0046148 73 33 1,000 2,977E-03 0,07420007 ! negative regulation of protein transport GO:0051224 74 33 1,000 2,977E-03 0,07345057 ! post-embryonic development GO:0009791 76 34 1,000 3,158E-03 0,07713832 ! formation of primary germ layer GO:0001704 76 34 1,000 3,158E-03 0,07637458 ! cell fate specification GO:0001708 56 34 1,000 3,158E-03 0,07562581 ! adult locomotory behavior GO:0008344 62 34 1,000 3,158E-03 0,07489158 ! positive regulation of endocytosis GO:0045807 56 35 1,000 3,344E-03 0,078542 ! mesoderm morphogenesis GO:0048332 80 35 1,000 3,344E-03 0,07779399 ! negative regulation of DNA binding GO:0043392 67 36 1,000 3,535E-03 0,08146371 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 3,731E-03 0,08517874 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 96 37 1,000 3,731E-03 0,08439005 ! maintenance of protein location in cell GO:0032507 89 37 1,000 3,731E-03 0,08361583 ! negative regulation of cell activation GO:0050866 69 37 1,000 3,731E-03 0,08285568 ! meiosis I GO:0007127 74 38 1,000 3,932E-03 0,08653355 ! regulation of protein stability GO:0031647 77 38 1,000 3,932E-03 0,08576093 ! pigment metabolic process GO:0042440 87 38 1,000 3,932E-03 0,08500198 ! negative regulation of binding GO:0051100 71 39 1,000 4,138E-03 0,08867007 ! carbohydrate homeostasis GO:0033500 59 39 1,000 4,138E-03 0,08789902 GO:0042593|glucose homeostasis, ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 4,564E-03 0,09612646 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 4,564E-03 0,09530487 ! maintenance of protein location GO:0045185 95 41 1,000 4,564E-03 0,0944972 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 4,785E-03 0,0982325 ! cytokinesis GO:0000910 84 42 1,000 4,785E-03 0,09741389 ! epithelial cell differentiation GO:0030855 83 43 1,000 5,01E-03 0,10116107 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 5,01E-03 0,10033188 ! hormone-mediated signaling GO:0009755 84 43 1,000 5,01E-03 0,09951617 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 5,01E-03 0,09871362 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 5,241E-03 0,1024246 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 5,476E-03 0,10616958 ! maintenance of location in cell GO:0051651 101 45 1,000 5,476E-03 0,1053336 ! activation of adenylate cyclase activity GO:0007190 94 46 1,000 5,716E-03 0,10908831 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 5,716E-03 0,10824267 ! leukocyte migration GO:0050900 75 46 1,000 5,716E-03 0,10741003 ! pigmentation GO:0043473 103 46 1,000 5,716E-03 0,10659011 ! positive regulation of protein transport GO:0051222 80 46 1,000 5,716E-03 0,10578261 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 6,21E-03 0,11405924 ! endosome transport GO:0016197 127 48 1,000 6,21E-03 0,11320806 ! positive regulation of cyclase activity GO:0031281 106 49 1,000 6,464E-03 0,11696593 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 6,464E-03 0,11610588 ! regulation of action potential GO:0001508 102 50 1,000 6,722E-03 0,11987103 ! positive regulation of lyase activity GO:0051349 107 50 1,000 6,722E-03 0,1190024 ! negative regulation of immune system process GO:0002683 101 51 1,000 6,986E-03 0,12277421 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 7,253E-03 0,1265728 ! activation of phospholipase C activity GO:0007202 110 54 1,000 7,803E-03 0,13519858 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 7,803E-03 0,13424648 ! membrane fusion GO:0006944 122 54 1,000 7,803E-03 0,13330769 ! glutamine family amino acid metabolic process GO:0009064 85 54 1,000 7,803E-03 0,13238194 ! regulation of cell shape GO:0008360 142 54 1,000 7,803E-03 0,13146897 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 8,085E-03 0,13528161 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 8,085E-03 0,13436132 ! skeletal muscle fiber development GO:0048741 130 56 1,000 8,371E-03 0,13817766 ! regulation of protein catabolic process GO:0042176 126 56 1,000 8,371E-03 0,13725029 ! muscle fiber development GO:0048747 131 57 1,000 8,662E-03 0,14106986 ! regulation of phospholipase activity GO:0010517 113 57 1,000 8,662E-03 0,14013563 ! regulation of intracellular transport GO:0032386 108 57 1,000 8,662E-03 0,13921368 ! gastrulation GO:0007369 122 58 1,000 8,957E-03 0,1430171 ! positive regulation of lipase activity GO:0060193 115 58 1,000 8,957E-03 0,14208842 ! maintenance of location GO:0051235 124 58 1,000 8,957E-03 0,14117172 ! establishment of organelle localization GO:0051656 122 59 1,000 9,257E-03 0,14495927 ! regulation of endocytosis GO:0030100 104 60 1,000 9,561E-03 0,14876761 ! adult behavior GO:0030534 104 60 1,000 9,561E-03 0,14782604 ! mesoderm development GO:0007498 128 63 1,000 0,01049921 0,16131813 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,01082081 0,16522025 ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,01114673 0,16913948 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,01114673 0,16809541 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,01181144 0,17702666 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 126 67 1,000 0,01181144 0,17594723 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01215019 0,17989642 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01217927 0,1792407 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01217927 0,1781674 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01217927 0,17710688 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01217927 0,17605891 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01217927 0,17502327 ! neuron fate determination GO:0048664 7 5 0,000 0,01217927 0,17399975 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01217927 0,17298812 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01217927 0,17198819 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01217927 0,17099975 ! polyol transport GO:0015791 12 5 0,000 0,01217927 0,17002261 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01217927 0,16905657 ! response to superoxide GO:0000303 10 5 0,000 0,01217927 0,16810145 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01217927 0,16715706 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01217927 0,16622322 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01217927 0,16529976 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01217927 0,1643865 ! female meiosis GO:0007143 10 5 0,000 0,01217927 0,16348328 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01217927 0,16258993 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01217927 0,16170629 ! hypothalamus development GO:0021854 9 5 0,000 0,01217927 0,1608322 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01217927 0,15996751 ! cobalt ion transport GO:0006824 11 5 0,000 0,01217927 0,15911207 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01217927 0,15826573 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01217927 0,15742834 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01217927 0,15659977 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01217927 0,15577988 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01217927 0,15496852 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01217927 0,15416558 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01217927 0,15337091 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01217927 0,15258439 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01217927 0,1518059 ! transposition GO:0032196 9 5 0,000 0,01217927 0,15103531 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01217927 0,15027251 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01217927 0,14951737 ! negative chemotaxis GO:0050919 16 5 0,000 0,01217927 0,14876978 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01217927 0,14802963 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01217927 0,14729681 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01217927 0,14657121 ! behavioral response to pain GO:0048266 10 5 0,000 0,01217927 0,14585273 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01217927 0,14514125 ! Notch receptor processing GO:0007220 11 5 0,000 0,01217927 0,14443668 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01217927 0,14373892 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01217927 0,14304787 ! micturition GO:0060073 9 5 0,000 0,01217927 0,14236343 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01217927 0,14168551 ! copulation GO:0007620 9 5 0,000 0,01217927 0,14101401 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01217927 0,14034885 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01217927 0,13968994 ! bioluminescence GO:0008218 9 5 0,000 0,01217927 0,13903718 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01217927 0,1383905 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01217927 0,1377498 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01217927 0,13711501 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01217927 0,13648604 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01217927 0,13586282 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01217927 0,13524526 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01217927 0,13463329 ! grooming behavior GO:0007625 6 5 0,000 0,01217927 0,13402683 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01217927 0,13342581 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01217927 0,13283016 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01217927 0,13223981 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01217927 0,13165468 ! response to protozoan GO:0001562 13 5 0,000 0,01217927 0,1310747 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01217927 0,13049981 ! lymph vessel development GO:0001945 10 5 0,000 0,01217927 0,12992994 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01217927 0,12936503 ! endochondral ossification GO:0001958 17 5 0,000 0,01217927 0,12880501 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01217927 0,12824981 ! single strand break repair GO:0000012 8 5 0,000 0,01217927 0,12769938 ! parathyroid gland development GO:0060017 14 5 0,000 0,01217927 0,12715366 ! anagen GO:0042640 7 5 0,000 0,01217927 0,12661258 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01217927 0,12607609 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01217927 0,12554412 ! cytokine secretion GO:0050663 15 5 0,000 0,01217927 0,12501662 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01217927 0,12449354 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01217927 0,12397482 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01217927 0,1234604 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01217927 0,12295023 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01217927 0,12244427 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01217927 0,12194245 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01217927 0,12144472 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01217927 0,12095104 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01217927 0,12046136 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01217927 0,11997563 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01217927 0,1194938 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01217927 0,11901583 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01217927 0,11854166 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01217927 0,11807126 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01217927 0,11760457 ! microvillus organization GO:0032528 8 5 0,000 0,01217927 0,11714156 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01217927 0,11668218 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01217927 0,11622639 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01217927 0,11577415 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01217927 0,11532541 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01217927 0,11488014 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01217927 0,11443829 ! polyol catabolic process GO:0046174 9 5 0,000 0,01217927 0,11399983 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01217927 0,11356472 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01217927 0,11313291 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01217927 0,11270438 ! muscle cell migration GO:0014812 8 5 0,000 0,01217927 0,11227908 ! mitochondrial fission GO:0000266 8 5 0,000 0,01217927 0,11185698 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01217927 0,11143804 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01217927 0,11102223 ! mRNA transcription GO:0009299 10 5 0,000 0,01217927 0,1106095 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01217927 0,11019984 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01217927 0,1097932 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01217927 0,10938955 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01217927 0,10898885 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01217927 0,10859108 ! monocyte activation GO:0042117 10 5 0,000 0,01217927 0,10819621 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01217927 0,10780419 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01217927 0,10741501 ! response to food GO:0032094 6 5 0,000 0,01217927 0,10702862 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01217927 0,10664501 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01217927 0,10626413 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01217927 0,10588597 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01217927 0,10551048 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01217927 0,10513766 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01217927 0,10476745 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01217927 0,10439985 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01217927 0,10403481 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01217927 0,10367232 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01217927 0,10331235 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01217927 0,10295487 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01217927 0,10259985 ! lipid glycosylation GO:0030259 7 5 0,000 0,01217927 0,10224727 ! nucleobase transport GO:0015851 6 5 0,000 0,01217927 0,10189711 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01217927 0,10154934 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01217927 0,10120393 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01217927 0,10086087 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01217927 0,10052012 ! basic amino acid transport GO:0015802 12 5 0,000 0,01217927 0,10018167 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01217927 0,09984549 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01217927 0,09951156 ! actin nucleation GO:0045010 11 5 0,000 0,01217927 0,09917986 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01217927 0,09885035 ! depurination GO:0045007 5 5 0,000 0,01217927 0,09852304 ! depyrimidination GO:0045008 10 5 0,000 0,01217927 0,09819788 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01217927 0,09787486 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01217927 0,09755396 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01217927 0,09723515 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01217927 0,09691843 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01217927 0,09660376 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01217927 0,09629112 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01217927 0,09598051 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01217927 0,09567189 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01217927 0,09536525 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01217927 0,09506056 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01217927 0,09475782 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01217927 0,09445701 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01217927 0,09415809 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01217927 0,09386106 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01217927 0,0935659 ! response to arsenic GO:0046685 11 5 0,000 0,01217927 0,09327259 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01217927 0,09298111 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01217927 0,09269145 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01217927 0,09240359 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01217927 0,09211751 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01217927 0,0918332 ! response to mercury ion GO:0046689 8 5 0,000 0,01217927 0,09155064 ! response to cadmium ion GO:0046686 7 5 0,000 0,01217927 0,09126981 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01217927 0,09099069 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01217927 0,09071328 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01217927 0,09043756 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01217927 0,0901635 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01217927 0,08989111 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01217927 0,08962035 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01217927 0,08935122 ! decidualization GO:0046697 11 5 0,000 0,01217927 0,0890837 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01217927 0,08881778 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01217927 0,08855344 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01217927 0,08829067 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01217927 0,08802946 ! embryonic cleavage GO:0040016 6 5 0,000 0,01217927 0,08776978 ! peroxisome fission GO:0016559 5 5 0,000 0,01217927 0,08751164 ! histone demethylation GO:0016577 13 5 0,000 0,01217927 0,087255 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01217927 0,08699987 ! mitotic recombination GO:0006312 9 5 0,000 0,01217927 0,08674623 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01217927 0,08649406 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01217927 0,08624335 ! metaphase plate congression GO:0051310 7 5 0,000 0,01217927 0,08599409 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01217927 0,08574627 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01217927 0,08549988 ! enteric nervous system development GO:0048484 8 5 0,000 0,01217927 0,08525489 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01217927 0,0850113 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01217927 0,08476911 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01217927 0,08452829 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01217927 0,08428883 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01217927 0,08405072 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01217927 0,08381396 ! B cell homeostasis GO:0001782 13 5 0,000 0,01217927 0,08357853 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01217927 0,08334442 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01217927 0,08311161 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01217927 0,0828801 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01217927 0,08264988 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01217927 0,08242093 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01217927 0,08219325 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01217927 0,08196682 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01217927 0,08174164 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01217927 0,08151769 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01217927 0,08129496 ! response to redox state GO:0051775 6 5 0,000 0,01217927 0,08107345 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01217927 0,08085314 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01217927 0,08063403 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01217927 0,0804161 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01217927 0,08019934 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01217927 0,07998375 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01217927 0,07976932 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01217927 0,07955603 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01217927 0,07934388 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01217927 0,07913286 ! striatum development GO:0021756 14 5 0,000 0,01217927 0,07892296 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01217927 0,07871417 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01217927 0,07850648 ! glial cell migration GO:0008347 10 5 0,000 0,01217927 0,07829989 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01217927 0,07809437 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01217927 0,07788994 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01217927 0,07768657 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01217927 0,07748426 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01217927 0,077283 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01217927 0,07708279 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01217927 0,07688361 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01217927 0,07668546 ! neuroprotection GO:0043526 8 5 0,000 0,01217927 0,07648832 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01217927 0,0762922 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01217927 0,07609708 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01217927 0,07590295 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01217927 0,07570981 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01217927 0,07551766 GO:0051497|negative regulation of stress fiber formation, ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01217927 0,07532647 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01217927 0,07513625 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01217927 0,07494699 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01217927 0,07475868 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01217927 0,07457132 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01217927 0,07438489 ! spindle assembly GO:0051225 6 5 0,000 0,01217927 0,07419939 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01217927 0,07401482 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01217927 0,07383116 ! protein palmitoylation GO:0018345 12 5 0,000 0,01217927 0,07364841 ! drug metabolic process GO:0017144 7 5 0,000 0,01217927 0,07346656 ! stem cell division GO:0017145 11 5 0,000 0,01217927 0,07328561 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01217927 0,07310554 ! organ regeneration GO:0031100 7 5 0,000 0,01217927 0,07292636 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01217927 0,07274806 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01217927 0,07257063 ! lung development GO:0030324 165 69 1,000 0,01249317 0,07425988 ! urogenital system development GO:0001655 149 69 1,000 0,01249317 0,07407964 ! appendage morphogenesis GO:0035107 150 72 1,000 0,01354728 0,08013562 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 0,01354728 0,07994205 ! appendage development GO:0048736 151 73 1,000 0,01390697 0,08186681 GO:0060173|limb development, ! respiratory system development GO:0060541 175 74 1,000 0,01427078 0,08380652 ! organelle localization GO:0051640 155 74 1,000 0,01427078 0,08360555 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01459747 0,08531488 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01459747 0,08511126 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01459747 0,08490862 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01459747 0,08470693 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01459747 0,08450621 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01459747 0,08430643 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01459747 0,08410759 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01459747 0,08390969 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01459747 0,08371272 ! response to oxygen radical GO:0000305 11 6 0,000 0,01459747 0,08351667 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01459747 0,08332154 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01459747 0,08312732 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01459747 0,082934 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01459747 0,08274157 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01459747 0,08255004 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01459747 0,0823594 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01459747 0,08216963 ! forebrain regionalization GO:0021871 9 6 0,000 0,01459747 0,08198073 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01459747 0,0817927 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01459747 0,08160553 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01459747 0,08141922 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01459747 0,08123376 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01459747 0,08104913 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01459747 0,08086535 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01459747 0,0806824 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01459747 0,08050027 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01459747 0,08031896 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01459747 0,08013847 ! malate metabolic process GO:0006108 13 6 0,000 0,01459747 0,07995879 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01459747 0,07977991 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01459747 0,07960183 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01459747 0,07942454 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01459747 0,07924804 ! protein refolding GO:0042026 15 6 0,000 0,01459747 0,07907233 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01459747 0,07889739 ! opsonization GO:0008228 8 6 0,000 0,01459747 0,07872322 ! mating behavior GO:0007617 7 6 0,000 0,01459747 0,07854982 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01459747 0,07837718 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01459747 0,0782053 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01459747 0,07803418 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01459747 0,0778638 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01459747 0,07769416 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01459747 0,07752526 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01459747 0,07735709 ! toxin metabolic process GO:0009404 11 6 0,000 0,01459747 0,07718965 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01459747 0,07702293 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01459747 0,07685694 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01459747 0,07669165 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01459747 0,07652708 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01459747 0,07636321 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01459747 0,07620004 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01459747 0,07603757 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01459747 0,07587578 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01459747 0,07571469 ! thymic T cell selection GO:0045061 16 6 0,000 0,01459747 0,07555428 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01459747 0,07539454 ! protein lipoylation GO:0009249 10 6 0,000 0,01459747 0,07523548 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01459747 0,07507709 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01459747 0,07491937 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01459747 0,0747623 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01459747 0,0746059 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01459747 0,07445014 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01459747 0,07429504 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01459747 0,07414058 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01459747 0,07398676 ! hyperosmotic response GO:0006972 10 6 0,000 0,01459747 0,07383358 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01459747 0,07368103 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01459747 0,07352911 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01459747 0,07337782 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01459747 0,07322714 ! urea metabolic process GO:0019627 7 6 0,000 0,01459747 0,07307709 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01459747 0,07292765 ! neutrophil activation GO:0042119 7 6 0,000 0,01459747 0,07277881 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01459747 0,07263059 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01459747 0,07248296 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01459747 0,07233594 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01459747 0,07218951 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01459747 0,07204367 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01459747 0,07189842 ! neuron apoptosis GO:0051402 15 6 0,000 0,01459747 0,07175376 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01459747 0,07160968 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01459747 0,07146617 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01459747 0,07132324 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01459747 0,07118088 ! carnitine transport GO:0015879 10 6 0,000 0,01459747 0,07103908 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01459747 0,07089785 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01459747 0,07075718 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01459747 0,07061707 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01459747 0,07047751 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01459747 0,0703385 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01459747 0,07020004 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01459747 0,07006212 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01459747 0,06992474 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01459747 0,0697879 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01459747 0,0696516 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01459747 0,06951583 ! response to UV-C GO:0010225 14 6 0,000 0,01459747 0,06938058 ! astrocyte development GO:0014002 16 6 0,000 0,01459747 0,06924586 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01459747 0,06911166 ! interaction with symbiont GO:0051702 14 6 0,000 0,01459747 0,06897799 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01459747 0,06884482 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01459747 0,06871217 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01459747 0,06858004 ! response to copper ion GO:0046688 10 6 0,000 0,01459747 0,0684484 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01459747 0,06831728 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01459747 0,06818665 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01459747 0,06805652 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01459747 0,06792689 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01459747 0,06779775 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01459747 0,06766911 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01459747 0,06754094 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01459747 0,06741327 ! hair follicle maturation GO:0048820 8 6 0,000 0,01459747 0,06728607 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01459747 0,06715936 ! Schwann cell development GO:0014044 15 6 0,000 0,01459747 0,06703312 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01459747 0,06690735 ! response to pheromone GO:0019236 6 6 0,000 0,01459747 0,06678206 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01459747 0,06665723 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01459747 0,06653287 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01459747 0,06640897 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01459747 0,06628554 ! subpallium development GO:0021544 15 6 0,000 0,01459747 0,06616256 ! neural tube patterning GO:0021532 8 6 0,000 0,01459747 0,06604003 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01459747 0,06591796 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01459747 0,06579634 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01459747 0,06567517 ! G2 phase GO:0051319 16 6 0,000 0,01459747 0,06555445 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01459747 0,06543416 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01459747 0,06531432 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01459747 0,06519492 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01459747 0,06507595 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01459747 0,06495741 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01459747 0,06483931 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01459747 0,06472163 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01459747 0,06460438 ! receptor internalization GO:0031623 11 6 0,000 0,01459747 0,06448756 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01459747 0,06437115 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01459747 0,06425517 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01459747 0,0641396 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01459747 0,06402445 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01459747 0,06390971 ! protein deubiquitination GO:0016579 16 6 0,000 0,01459747 0,06379538 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01459747 0,06368146 ! protein destabilization GO:0031648 9 6 0,000 0,01459747 0,06356795 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01459747 0,06345484 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01459747 0,06334213 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01459747 0,06322982 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01459747 0,06311791 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01459747 0,06300639 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01459747 0,06289527 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01459747 0,06278454 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01459747 0,0626742 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01459747 0,06256424 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01459747 0,06245467 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01459747 0,06234549 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01459747 0,06223668 ! neural plate development GO:0001840 9 6 0,000 0,01459747 0,06212826 ! catecholamine transport GO:0051937 9 6 0,000 0,01459747 0,06202021 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01459747 0,06191253 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01459747 0,06180523 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01459747 0,0616983 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01459747 0,06159174 ! maternal placenta development GO:0001893 12 6 0,000 0,01459747 0,06148555 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01459747 0,06137972 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01459747 0,06127426 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01459747 0,06116916 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01459747 0,06106442 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01459747 0,06096003 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01459747 0,060856 GO:0055081|anion homeostasis, ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01463869 0,06092388 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,01463869 0,06082027 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,01463869 0,06071701 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01501068 0,06215438 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,01538672 0,06360365 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01538672 0,06349621 ! blood coagulation GO:0007596 151 79 1,000 0,01615089 0,06653732 GO:0050817|coagulation, ! meiosis GO:0007126 143 81 1,000 0,01693103 0,06963386 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,01693103 0,06951682 ! response to hypoxia GO:0001666 178 81 1,000 0,01693103 0,06940018 ! tRNA transcription GO:0009304 17 7 0,000 0,01700982 0,06960634 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01700982 0,06948994 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01700982 0,06937393 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01700982 0,06925831 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01700982 0,06914307 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01700982 0,06902821 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01700982 0,06891374 ! sleep GO:0030431 16 7 0,000 0,01700982 0,06879964 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01700982 0,06868593 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01700982 0,06857258 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01700982 0,06845961 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01700982 0,06834701 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01700982 0,06823479 GO:0070193|synaptonemal complex organization, ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01700982 0,06812293 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01700982 0,06801143 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01700982 0,0679003 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01700982 0,06778953 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01700982 0,06767913 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01700982 0,06756908 ! glycolipid transport GO:0046836 11 7 0,000 0,01700982 0,06745939 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01700982 0,06735006 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01700982 0,06724108 ! neuron adhesion GO:0007158 14 7 0,000 0,01700982 0,06713245 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01700982 0,06702417 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01700982 0,06691624 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01700982 0,06680866 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01700982 0,06670142 ! mRNA stabilization GO:0048255 18 7 0,000 0,01700982 0,06659453 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01700982 0,06648798 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01700982 0,06638176 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01700982 0,06627589 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01700982 0,06617036 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01700982 0,06606516 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01700982 0,06596029 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01700982 0,06585576 ! lipoprotein transport GO:0042953 14 7 0,000 0,01700982 0,06575156 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01700982 0,06564769 ! rhythmic behavior GO:0007622 17 7 0,000 0,01700982 0,06554414 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01700982 0,06544092 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01700982 0,06533803 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01700982 0,06523545 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01700982 0,0651332 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01700982 0,06503127 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01700982 0,06492966 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01700982 0,06482837 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01700982 0,06472739 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01700982 0,06462673 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01700982 0,06452637 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01700982 0,06442633 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01700982 0,0643266 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01700982 0,06422718 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01700982 0,06412806 ! spinal cord patterning GO:0021511 14 7 0,000 0,01700982 0,06402925 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01700982 0,06393075 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01700982 0,06383254 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01700982 0,06373464 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01700982 0,06363704 ! adrenal gland development GO:0030325 17 7 0,000 0,01700982 0,06353973 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01700982 0,06344272 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01700982 0,06334601 ! ovulation GO:0030728 10 7 0,000 0,01700982 0,0632496 ! adenohypophysis development GO:0021984 11 7 0,000 0,01700982 0,06315347 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01700982 0,06305764 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01700982 0,0629621 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01700982 0,06286685 ! microtubule nucleation GO:0007020 21 7 0,000 0,01700982 0,06277188 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01700982 0,0626772 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01700982 0,06258281 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01700982 0,0624887 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01700982 0,06239487 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01700982 0,06230133 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01700982 0,06220806 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01700982 0,06211507 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01700982 0,06202237 ! galactose metabolic process GO:0006012 13 7 0,000 0,01700982 0,06192993 ! vesicle fusion GO:0006906 20 7 0,000 0,01700982 0,06183777 ! response to dietary excess GO:0002021 8 7 0,000 0,01700982 0,06174589 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01700982 0,06165428 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01700982 0,06156294 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01700982 0,06147187 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01700982 0,06138107 ! organ growth GO:0035265 15 7 0,000 0,01700982 0,06129054 ! nucleoside transport GO:0015858 11 7 0,000 0,01700982 0,06120027 ! nucleoside salvage GO:0043174 11 7 0,000 0,01700982 0,06111027 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01700982 0,06102054 ! male sex determination GO:0030238 15 7 0,000 0,01700982 0,06093106 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01700982 0,06084185 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01700982 0,0607529 ! parturition GO:0007567 16 7 0,000 0,01700982 0,06066421 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01700982 0,06057578 ! rRNA modification GO:0000154 14 7 0,000 0,01700982 0,06048761 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01700982 0,06039969 ! spindle checkpoint GO:0031577 16 7 0,000 0,01700982 0,06031202 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01700982 0,06022462 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01700982 0,06013746 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01700982 0,06005056 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01700982 0,0599639 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01700982 0,0598775 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01700982 0,05979134 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01700982 0,05970544 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01700982 0,05961978 ! fibrinolysis GO:0042730 11 7 0,000 0,01700982 0,05953436 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01700982 0,05944919 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01700982 0,05936426 ! eating behavior GO:0042755 8 7 0,000 0,01700982 0,05927958 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01700982 0,05919513 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01700982 0,05911093 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01700982 0,05902697 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01700982 0,05894324 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01700982 0,05885975 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01700982 0,0587765 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01700982 0,05869348 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01700982 0,0586107 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01700982 0,05852815 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01700982 0,05844583 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01700982 0,05836374 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01700982 0,05828189 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01700982 0,05820026 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01700982 0,05811886 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01700982 0,05803769 ! histone ubiquitination GO:0016574 9 7 0,000 0,01700982 0,05795674 ! regulation of meiosis GO:0040020 12 7 0,000 0,01700982 0,05787602 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01700982 0,05779553 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01700982 0,05771526 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01700982 0,05763521 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01700982 0,05755538 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01700982 0,05747577 ! transcription termination GO:0006353 14 7 0,000 0,01700982 0,05739639 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01700982 0,05731722 ! anaphase GO:0051322 18 7 0,000 0,01700982 0,05723827 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01700982 0,05715954 ! axonal fasciculation GO:0007413 19 7 0,000 0,01700982 0,05708102 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01700982 0,05700272 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01700982 0,05692464 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01700982 0,05684676 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01700982 0,0567691 ! diuresis GO:0030146 12 7 0,000 0,01700982 0,05669166 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01700982 0,05661442 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01700982 0,05653739 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01700982 0,05646058 ! antibiotic transport GO:0042891 9 7 0,000 0,01700982 0,05638397 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01700982 0,05630757 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01700982 0,05623137 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01700982 0,05615538 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01700982 0,0560796 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01700982 0,05600402 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01700982 0,05592865 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01700982 0,05585347 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01700982 0,0557785 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01700982 0,05570373 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01700982 0,05562916 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01700982 0,05555479 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01700982 0,05548062 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01700982 0,05540665 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01700982 0,05533287 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01700982 0,05525929 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01700982 0,0551859 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01700982 0,05511271 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01700982 0,05503971 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01700982 0,05496691 ! muscle adaptation GO:0043500 13 7 0,000 0,01700982 0,0548943 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01700982 0,05482188 ! retina homeostasis GO:0001895 12 7 0,000 0,01700982 0,05474965 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01700982 0,05467761 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01700982 0,05460576 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01700982 0,0545341 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01700982 0,05446263 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,01732704 0,05540569 ! meiotic cell cycle GO:0051321 144 82 1,000 0,01732704 0,05533327 ! response to oxygen levels GO:0070482 183 83 1,000 0,01772697 0,05653653 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,01772697 0,05646282 ! T cell activation GO:0042110 189 84 1,000 0,01813081 0,05767391 ! hemostasis GO:0007599 165 85 1,000 0,01853853 0,05889419 ! negative regulation of transport GO:0051051 164 85 1,000 0,01853853 0,0588177 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01853853 0,05874142 ! regulation of protein transport GO:0051223 165 87 1,000 0,01936555 0,06128245 GO:0070201|regulation of establishment of protein localization, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01941633 0,06136363 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01941633 0,06128435 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01941633 0,06120528 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01941633 0,0611264 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01941633 0,06104773 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01941633 0,06096927 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01941633 0,060891 ! male meiosis GO:0007140 9 8 0,000 0,01941633 0,06081293 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01941633 0,06073507 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01941633 0,0606574 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01941633 0,06057993 ! meiotic prophase I GO:0007128 14 8 0,000 0,01941633 0,06050266 ! response to zinc ion GO:0010043 12 8 0,000 0,01941633 0,06042559 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01941633 0,06034871 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01941633 0,06027203 ! oligopeptide transport GO:0006857 16 8 0,000 0,01941633 0,06019554 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01941633 0,06011925 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01941633 0,06004315 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01941633 0,05996724 ! signal peptide processing GO:0006465 12 8 0,000 0,01941633 0,05989153 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01941633 0,059816 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01941633 0,05974067 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01941633 0,05966552 ! succinate metabolic process GO:0006105 17 8 0,000 0,01941633 0,05959056 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01941633 0,0595158 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01941633 0,05944121 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01941633 0,05936682 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01941633 0,05929261 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01941633 0,05921859 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01941633 0,05914475 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01941633 0,05907109 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01941633 0,05899762 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01941633 0,05892433 ! reflex GO:0060004 17 8 0,000 0,01941633 0,05885123 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01941633 0,0587783 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01941633 0,05870556 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01941633 0,05863299 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01941633 0,0585606 ! pigment granule organization GO:0048753 17 8 0,000 0,01941633 0,0584884 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01941633 0,05841637 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01941633 0,05834451 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01941633 0,05827284 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01941633 0,05820134 ! histidine catabolic process GO:0006548 10 8 0,000 0,01941633 0,05813001 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01941633 0,05805886 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01941633 0,05798788 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01941633 0,05791708 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01941633 0,05784645 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01941633 0,05777599 ! melanin metabolic process GO:0006582 17 8 0,000 0,01941633 0,0577057 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01941633 0,05763559 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01941633 0,05756564 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01941633 0,05749587 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01941633 0,05742626 ! macrophage activation GO:0042116 13 8 0,000 0,01941633 0,05735682 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01941633 0,05728755 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01941633 0,05721844 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01941633 0,0571495 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01941633 0,05708073 ! purine salvage GO:0043101 12 8 0,000 0,01941633 0,05701213 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01941633 0,05694368 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01941633 0,05687541 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01941633 0,05680729 ! osteoblast development GO:0002076 17 8 0,000 0,01941633 0,05673934 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01941633 0,05667155 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01941633 0,05660392 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01941633 0,05653646 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01941633 0,05646915 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01941633 0,05640201 ! response to UV-B GO:0010224 17 8 0,000 0,01941633 0,05633502 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01941633 0,0562682 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01941633 0,05620153 ! intermediate filament organization GO:0045109 12 8 0,000 0,01941633 0,05613502 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01941633 0,05606866 ! cellular extravasation GO:0045123 13 8 0,000 0,01941633 0,05600247 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01941633 0,05593643 ! response to antibiotic GO:0046677 11 8 0,000 0,01941633 0,05587054 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01941633 0,05580481 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01941633 0,05573923 ! DNA topological change GO:0006265 12 8 0,000 0,01941633 0,05567381 ! response to tropane GO:0014073 15 8 0,000 0,01941633 0,05560854 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01941633 0,05554343 ! melanosome transport GO:0032402 13 8 0,000 0,01941633 0,05547847 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,01941633 0,05541365 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01941633 0,05534899 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01941633 0,05528449 ! mast cell activation GO:0045576 14 8 0,000 0,01941633 0,05522013 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01941633 0,05515592 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01941633 0,05509186 ! gas homeostasis GO:0033483 14 8 0,000 0,01941633 0,05502795 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01941633 0,05496418 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01941633 0,05490057 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01941633 0,0548371 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01941633 0,05477377 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01941633 0,0547106 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01941633 0,05464757 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01941633 0,05458468 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01941633 0,05452194 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01941633 0,05445934 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01941633 0,05439689 ! response to tumor cell GO:0002347 16 8 0,000 0,01941633 0,05433458 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01941633 0,05427241 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01941633 0,05421039 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01941633 0,0541485 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01941633 0,05408676 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01941633 0,05402516 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01941633 0,0539637 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01941633 0,05390237 ! hormone catabolic process GO:0042447 17 8 0,000 0,01941633 0,05384119 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01941633 0,05378015 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01941633 0,05371924 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01941633 0,05365847 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01941633 0,05359784 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01941633 0,05353735 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01941633 0,05347699 ! adult feeding behavior GO:0008343 10 8 0,000 0,01941633 0,05341677 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01941633 0,05335668 ! ATP catabolic process GO:0006200 11 8 0,000 0,01941633 0,05329673 ! blastocyst growth GO:0001832 19 8 0,000 0,01941633 0,05323691 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01941633 0,05317723 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01941633 0,05311768 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01941633 0,05305826 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01941633 0,05299898 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01941633 0,05293983 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01941633 0,05288081 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01941633 0,05282192 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01941633 0,05276317 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01941633 0,05270454 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01941633 0,05264605 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01941633 0,05258768 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01941633 0,05252944 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01941633 0,05247134 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01941633 0,05241336 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01941633 0,05235551 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01941633 0,05229778 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01941633 0,05224019 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01941633 0,05218272 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01941633 0,05212537 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01941633 0,05206815 ! regulation of DNA binding GO:0051101 167 89 1,000 0,02020787 0,05413139 ! tube morphogenesis GO:0035239 194 89 1,000 0,02020787 0,0540721 ! regulation of neurological system process GO:0031644 175 89 1,000 0,02020787 0,05401294 ! gland development GO:0048732 220 91 1,000 0,02106531 0,05624324 ! axon extension GO:0048675 16 9 0,000 0,02181701 0,05818664 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02181701 0,05812319 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02181701 0,05805987 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02181701 0,0579967 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02181701 0,05793366 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02181701 0,05787075 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02181701 0,05780799 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02181701 0,05774536 ! reproductive behavior GO:0019098 22 9 0,000 0,02181701 0,05768286 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02181701 0,0576205 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02181701 0,05755828 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02181701 0,05749619 ! UTP metabolic process GO:0046051 10 9 0,000 0,02181701 0,05743423 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02181701 0,05737241 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02181701 0,05731071 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02181701 0,05724916 ! artery development GO:0060840 25 9 0,000 0,02181701 0,05718773 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02181701 0,05712644 ! regulation of glycolysis GO:0006110 20 9 0,000 0,02181701 0,05706527 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02181701 0,05700424 ! equilibrioception GO:0050957 20 9 0,000 0,02181701 0,05694334 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02181701 0,05688257 ! chemosensory behavior GO:0007635 21 9 0,000 0,02181701 0,05682192 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02181701 0,05676141 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02181701 0,05670103 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02181701 0,05664077 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02181701 0,05658064 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02181701 0,05652064 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02181701 0,05646077 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02181701 0,05640102 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02181701 0,0563414 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02181701 0,05628191 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02181701 0,05622254 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02181701 0,05616329 ! protein targeting to ER GO:0045047 25 9 0,000 0,02181701 0,05610417 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02181701 0,05604518 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02181701 0,05598631 ! T cell selection GO:0045058 27 9 0,000 0,02181701 0,05592756 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,02181701 0,05586894 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02181701 0,05581043 ! glycine catabolic process GO:0006546 15 9 0,000 0,02181701 0,05575206 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02181701 0,0556938 ! endosome organization GO:0007032 20 9 0,000 0,02181701 0,05563566 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02181701 0,05557765 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02181701 0,05551975 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02181701 0,05546198 ! mannose metabolic process GO:0006013 13 9 0,000 0,02181701 0,05540433 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02181701 0,0553468 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02181701 0,05528938 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02181701 0,05523209 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02181701 0,05517491 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02181701 0,05511785 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02181701 0,05506091 ! retinol metabolic process GO:0042572 20 9 0,000 0,02181701 0,05500409 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02181701 0,05494739 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02181701 0,0548908 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02181701 0,05483433 ! macrophage differentiation GO:0030225 15 9 0,000 0,02181701 0,05477797 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02181701 0,05472173 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02181701 0,0546656 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02181701 0,05460959 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02181701 0,0545537 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02181701 0,05449792 ! response to amine stimulus GO:0014075 13 9 0,000 0,02181701 0,05444225 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02181701 0,0543867 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02181701 0,05433126 ! erythrocyte development GO:0048821 17 9 0,000 0,02181701 0,05427593 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02181701 0,05422072 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02181701 0,05416561 ! renal water homeostasis GO:0003091 15 9 0,000 0,02181701 0,05411062 ! postreplication repair GO:0006301 25 9 0,000 0,02181701 0,05405575 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02181701 0,05400098 ! icosanoid secretion GO:0032309 15 9 0,000 0,02181701 0,05394632 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02181701 0,05389177 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02181701 0,05383734 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02181701 0,05378301 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02181701 0,0537288 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02181701 0,05367469 ! sterol catabolic process GO:0016127 14 9 0,000 0,02181701 0,05362069 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02181701 0,0535668 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02181701 0,05351302 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02181701 0,05345934 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02181701 0,05340578 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02181701 0,05335232 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02181701 0,05329896 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02181701 0,05324572 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02181701 0,05319258 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02181701 0,05313955 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02181701 0,05308662 ! pigment granule transport GO:0051904 17 9 0,000 0,02181701 0,0530338 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02181701 0,05298108 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02181701 0,05292847 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02181701 0,05287596 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02181701 0,05282355 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02181701 0,05277125 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02181701 0,05271906 ! mitochondrion localization GO:0051646 18 9 0,000 0,02181701 0,05266696 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,02193772 0,05290607 ! sex differentiation GO:0007548 171 96 1,000 0,02327402 0,05607341 ! regulation of protein localization GO:0032880 188 97 1,000 0,02372677 0,05710787 ! leukocyte differentiation GO:0002521 232 98 1,000 0,02418313 0,05814899 ! forebrain development GO:0030900 210 98 1,000 0,02418313 0,05809181 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02421189 0,05810378 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02421189 0,05804676 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,02421189 0,05798985 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02421189 0,05793305 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02421189 0,05787637 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02421189 0,05781979 ! associative learning GO:0008306 21 10 0,000 0,02421189 0,05776333 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,02421189 0,05770697 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02421189 0,05765073 ! phosphate transport GO:0006817 24 10 0,000 0,02421189 0,05759459 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02421189 0,05753857 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02421189 0,05748265 ! CTP metabolic process GO:0046036 11 10 0,000 0,02421189 0,05742684 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02421189 0,05737114 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02421189 0,05731555 ! GTP metabolic process GO:0046039 11 10 0,000 0,02421189 0,05726006 ! elastic fiber assembly GO:0048251 17 10 0,000 0,02421189 0,05720469 ! social behavior GO:0035176 29 10 0,000 0,02421189 0,05714942 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02421189 0,05709425 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02421189 0,0570392 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02421189 0,05698425 ! androgen metabolic process GO:0008209 17 10 0,000 0,02421189 0,0569294 ! phospholipid efflux GO:0033700 19 10 0,000 0,02421189 0,05687466 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02421189 0,05682003 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02421189 0,0567655 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02421189 0,05671107 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02421189 0,05665675 ! lung alveolus development GO:0048286 26 10 0,000 0,02421189 0,05660253 ! pathogenesis GO:0009405 17 10 0,000 0,02421189 0,05654842 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02421189 0,05649441 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02421189 0,0564405 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02421189 0,0563867 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02421189 0,056333 ! endoderm development GO:0007492 18 10 0,000 0,02421189 0,0562794 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02421189 0,0562259 ! arginine catabolic process GO:0006527 17 10 0,000 0,02421189 0,0561725 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02421189 0,05611921 ! proline metabolic process GO:0006560 13 10 0,000 0,02421189 0,05606602 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02421189 0,05601292 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02421189 0,05595993 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02421189 0,05590704 ! V(D)J recombination GO:0033151 34 10 0,000 0,02421189 0,05585425 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02421189 0,05580155 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02421189 0,05574896 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02421189 0,05569647 ! B cell proliferation GO:0042100 19 10 0,000 0,02421189 0,05564407 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02421189 0,05559177 ! multicellular organism growth GO:0035264 19 10 0,000 0,02421189 0,05553957 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02421189 0,05548747 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02421189 0,05543547 ! ruffle organization GO:0031529 17 10 0,000 0,02421189 0,05538356 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02421189 0,05533176 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02421189 0,05528004 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02421189 0,05522843 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02421189 0,05517691 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02421189 0,05512549 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02421189 0,05507416 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02421189 0,05502293 ! motor axon guidance GO:0008045 22 10 0,000 0,02421189 0,05497179 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02421189 0,05492075 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02421189 0,0548698 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02421189 0,05481895 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02421189 0,05476819 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02421189 0,05471753 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02421189 0,05466696 ! segment specification GO:0007379 15 10 0,000 0,02421189 0,05461648 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02421189 0,05456609 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02421189 0,0545158 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02421189 0,0544656 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02421189 0,0544155 ! response to dsRNA GO:0043331 23 10 0,000 0,02421189 0,05436548 ! DNA ligation GO:0006266 18 10 0,000 0,02421189 0,05431556 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02421189 0,05426573 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02421189 0,05421599 ! melanosome localization GO:0032400 16 10 0,000 0,02421189 0,05416634 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02421189 0,05411679 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02421189 0,05406732 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02421189 0,05401794 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02421189 0,05396866 ! induction of an organ GO:0001759 17 10 0,000 0,02421189 0,05391946 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02421189 0,05387035 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02421189 0,05382133 ! protein sumoylation GO:0016925 17 10 0,000 0,02421189 0,05377241 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02421189 0,05372357 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02421189 0,05367482 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02421189 0,05362615 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02421189 0,05357758 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02421189 0,05352909 ! salivary gland development GO:0007431 28 10 0,000 0,02421189 0,05348069 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02421189 0,05343238 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02421189 0,05338416 ! midbrain development GO:0030901 14 10 0,000 0,02421189 0,05333602 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02421189 0,05328797 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02421189 0,05324001 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02421189 0,05319213 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02421189 0,05314434 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02421189 0,05309663 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02421189 0,05304901 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02421189 0,05300148 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02421189 0,05295403 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02421189 0,05290666 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02421189 0,05285938 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02421189 0,05281218 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02421189 0,05276507 ! blastocyst formation GO:0001825 18 10 0,000 0,02421189 0,05271805 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02421189 0,0526711 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02421189 0,05262424 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02421189 0,05257746 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02421189 0,05253077 ! response to nicotine GO:0035094 20 10 0,000 0,02421189 0,05248416 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02421189 0,05243763 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02421189 0,05239118 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,02510662 0,05427918 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 1,000 0,02510662 0,05423119 ! hormone metabolic process GO:0042445 171 100 1,000 0,02510662 0,05418328 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02660097 0,05735761 ! respiratory burst GO:0045730 17 11 0,000 0,02660097 0,05730703 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02660097 0,05725654 ! neuron fate specification GO:0048665 18 11 0,000 0,02660097 0,05720613 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02660097 0,05715582 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02660097 0,0571056 ! thyroid gland development GO:0030878 26 11 0,000 0,02660097 0,05705546 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,02660097 0,05700541 ! synapsis GO:0007129 14 11 0,000 0,02660097 0,05695545 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02660097 0,05690558 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02660097 0,05685579 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02660097 0,05680609 ! response to pain GO:0048265 27 11 0,000 0,02660097 0,05675648 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02660097 0,05670695 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02660097 0,05665751 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02660097 0,05660816 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02660097 0,05655889 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02660097 0,05650971 ! bone resorption GO:0045453 16 11 0,000 0,02660097 0,05646062 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02660097 0,05641161 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02660097 0,05636268 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02660097 0,05631384 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02660097 0,05626508 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02660097 0,05621641 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02660097 0,05616782 GO:0009075|histidine family amino acid metabolic process, ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02660097 0,05611932 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02660097 0,0560709 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02660097 0,05602256 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02660097 0,05597431 ! UV protection GO:0009650 20 11 0,000 0,02660097 0,05592614 ! adult heart development GO:0007512 16 11 0,000 0,02660097 0,05587805 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02660097 0,05583004 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02660097 0,05578212 ! macroautophagy GO:0016236 19 11 0,000 0,02660097 0,05573428 ! temperature homeostasis GO:0001659 18 11 0,000 0,02660097 0,05568652 ! behavioral fear response GO:0001662 27 11 0,000 0,02660097 0,05563884 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02660097 0,05559125 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02660097 0,05554373 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02660097 0,0554963 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02660097 0,05544895 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02660097 0,05540168 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02660097 0,05535449 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02660097 0,05530738 ! regulation of organ growth GO:0046620 14 11 0,000 0,02660097 0,05526035 ! pigment granule localization GO:0051875 20 11 0,000 0,02660097 0,0552134 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02660097 0,05516653 ! vasoconstriction GO:0042310 20 11 0,000 0,02660097 0,05511974 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02660097 0,05507302 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02660097 0,05502639 ! embryonic axis specification GO:0000578 19 11 0,000 0,02660097 0,05497984 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02660097 0,05493336 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02660097 0,05488697 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02660097 0,05484065 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02660097 0,05479441 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02660097 0,05474825 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02660097 0,05470216 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02660097 0,05465616 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02660097 0,05461023 ! prophase GO:0051324 17 11 0,000 0,02660097 0,05456437 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02660097 0,0545186 ! nucleosome positioning GO:0016584 15 11 0,000 0,02660097 0,0544729 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02660097 0,05442728 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02660097 0,05438173 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02660097 0,05433626 ! apical protein localization GO:0045176 18 11 0,000 0,02660097 0,05429087 ! acid secretion GO:0046717 20 11 0,000 0,02660097 0,05424555 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02660097 0,05420031 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02660097 0,05415514 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02660097 0,05411005 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02660097 0,05406503 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02660097 0,05402009 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02660097 0,05397522 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02660097 0,05393043 ! cholesterol efflux GO:0033344 21 11 0,000 0,02660097 0,05388571 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02660097 0,05384107 ! oocyte development GO:0048599 20 11 0,000 0,02660097 0,0537965 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02660097 0,053752 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02660097 0,05370758 ! embryonic gut development GO:0048566 19 11 0,000 0,02660097 0,05366323 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02660097 0,05361895 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02660097 0,05357475 ! activation of innate immune response GO:0002218 16 11 0,000 0,02660097 0,05353062 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02660097 0,05348656 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02660097 0,05344257 ! lysogeny GO:0030069 22 11 0,000 0,02660097 0,05339866 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02660097 0,05335482 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02660097 0,05331105 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02660097 0,05326735 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02660097 0,05322373 ! nucleus localization GO:0051647 22 11 0,000 0,02660097 0,05318017 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02898427 0,05789744 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02898427 0,05785013 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02898427 0,05780291 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02898427 0,05775576 ! virus-host interaction GO:0019048 30 12 0,000 0,02898427 0,05770869 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02898427 0,0576617 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02898427 0,05761478 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02898427 0,05756794 ! protein complex disassembly GO:0043241 28 12 0,000 0,02898427 0,05752117 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02898427 0,05747448 ! hippocampus development GO:0021766 29 12 0,000 0,02898427 0,05742787 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02898427 0,05738133 ! T cell proliferation GO:0042098 32 12 0,000 0,02898427 0,05733487 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02898427 0,05728848 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02898427 0,05724217 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02898427 0,05719593 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02898427 0,05714977 ! drug transport GO:0015893 16 12 0,000 0,02898427 0,05710368 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02898427 0,05705767 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02898427 0,05701173 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02898427 0,05696586 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02898427 0,05692007 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02898427 0,05687435 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02898427 0,0568287 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02898427 0,05678313 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02898427 0,05673763 ! lipid digestion GO:0044241 21 12 0,000 0,02898427 0,05669221 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02898427 0,05664685 ! entry into host cell GO:0030260 34 12 0,000 0,02898427 0,05660157 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02898427 0,05655636 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02898427 0,05651123 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02898427 0,05646616 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02898427 0,05642117 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02898427 0,05637625 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02898427 0,0563314 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02898427 0,05628662 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02898427 0,05624191 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02898427 0,05619727 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02898427 0,05615271 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02898427 0,05610821 ! cranial nerve development GO:0021545 23 12 0,000 0,02898427 0,05606379 ! fucose catabolic process GO:0019317 25 12 0,000 0,02898427 0,05601943 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02898427 0,05597515 ! histone acetylation GO:0016573 27 12 0,000 0,02898427 0,05593094 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02898427 0,05588679 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02898427 0,05584272 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02898427 0,05579871 ! zymogen activation GO:0031638 18 12 0,000 0,02898427 0,05575478 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02898427 0,05571091 ! T cell homeostasis GO:0043029 28 12 0,000 0,02898427 0,05566711 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02898427 0,05562338 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02898427 0,05557972 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02898427 0,05553613 ! oocyte differentiation GO:0009994 21 12 0,000 0,02898427 0,05549261 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02898427 0,05544915 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02898427 0,05540576 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02898427 0,05536244 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02898427 0,05531919 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02898427 0,05527601 ! defense response to fungus GO:0050832 15 12 0,000 0,02898427 0,05523289 ! developmental induction GO:0031128 22 12 0,000 0,02898427 0,05518984 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02898427 0,05514686 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02898427 0,05510394 ! response to cold GO:0009409 17 12 0,000 0,02898427 0,05506109 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02898427 0,05501831 ! localization within membrane GO:0051668 26 12 0,000 0,02898427 0,05497559 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,0313618 0,059439 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0313618 0,05939292 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,0313618 0,05934692 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0313618 0,05930098 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0313618 0,05925512 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,0313618 0,05920933 ! peroxisomal transport GO:0043574 28 13 0,000 0,0313618 0,05916361 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,0313618 0,05911795 ! cartilage condensation GO:0001502 22 13 0,000 0,0313618 0,05907237 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,0313618 0,05902686 ! organelle fusion GO:0048284 36 13 0,000 0,0313618 0,05898142 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,0313618 0,05893605 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,0313618 0,05889075 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,0313618 0,05884552 ! endocrine pancreas development GO:0031018 25 13 0,000 0,0313618 0,05880036 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,0313618 0,05875527 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,0313618 0,05871024 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,0313618 0,05866529 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,0313618 0,0586204 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,0313618 0,05857559 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0313618 0,05853084 ! methionine metabolic process GO:0006555 31 13 0,000 0,0313618 0,05848616 ! plasma membrane organization GO:0007009 27 13 0,000 0,0313618 0,05844155 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,0313618 0,058397 ! Golgi organization GO:0007030 25 13 0,000 0,0313618 0,05835253 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,0313618 0,05830812 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,0313618 0,05826378 ! cytokine metabolic process GO:0042107 24 13 0,000 0,0313618 0,05821951 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,0313618 0,0581753 ! exocrine system development GO:0035272 34 13 0,000 0,0313618 0,05813116 ! asymmetric protein localization GO:0008105 24 13 0,000 0,0313618 0,05808709 ! monoamine transport GO:0015844 21 13 0,000 0,0313618 0,05804308 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,0313618 0,05799914 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,0313618 0,05795527 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,0313618 0,05791147 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,0313618 0,05786773 ! protein homotetramerization GO:0051289 24 13 0,000 0,0313618 0,05782405 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,0313618 0,05778044 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,0313618 0,0577369 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,0313618 0,05769343 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,0313618 0,05765001 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,0313618 0,05760667 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0313618 0,05756339 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,0313618 0,05752017 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,0313618 0,05747702 ! histone methylation GO:0016571 29 13 0,000 0,0313618 0,05743393 ! chromatin silencing GO:0006342 29 13 0,000 0,0313618 0,05739091 ! gland morphogenesis GO:0022612 31 13 0,000 0,0313618 0,05734796 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,0313618 0,05730506 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,0313618 0,05726223 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0313618 0,05721947 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,0313618 0,05717677 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,0313618 0,05713413 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,0313618 0,05709156 ! spleen development GO:0048536 24 13 0,000 0,0313618 0,05704905 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,0313618 0,0570066 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,0313618 0,05696421 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,0313618 0,05692189 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,0313618 0,05687964 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,0313618 0,05683744 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0313618 0,05679531 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,0313618 0,05675324 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,0313618 0,05671123 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,0313618 0,05666928 ! insulin secretion GO:0030073 24 13 0,000 0,0313618 0,0566274 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,0313618 0,05658558 ! acrosome reaction GO:0007340 19 13 0,000 0,0313618 0,05654381 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,0313618 0,05650212 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,0313618 0,05646048 ! rRNA transcription GO:0009303 28 14 0,000 0,03373357 0,06068565 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03373357 0,060641 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03373357 0,06059641 ! water transport GO:0006833 21 14 0,000 0,03373357 0,06055188 GO:0042044|fluid transport, ! non-recombinational repair GO:0000726 29 14 0,000 0,03373357 0,06050743 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03373357 0,06046303 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03373357 0,06041871 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03373357 0,06037444 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03373357 0,06033024 ! lipid localization GO:0010876 32 14 0,000 0,03373357 0,06028611 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03373357 0,06024204 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03373357 0,06019804 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03373357 0,0601541 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03373357 0,06011022 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03373357 0,06006641 ! arginine metabolic process GO:0006525 21 14 0,000 0,03373357 0,06002266 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03373357 0,05997898 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03373357 0,05993536 ! regulation of heart rate GO:0002027 25 14 0,000 0,03373357 0,0598918 ! fear response GO:0042596 34 14 0,000 0,03373357 0,0598483 ! organic alcohol transport GO:0015850 29 14 0,000 0,03373357 0,05980487 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03373357 0,0597615 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03373357 0,0597182 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03373357 0,05967496 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03373357 0,05963178 ! bone mineralization GO:0030282 18 14 0,000 0,03373357 0,05958866 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03373357 0,0595456 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03373357 0,05950261 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03373357 0,05945968 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03373357 0,05941681 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03373357 0,059374 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03373357 0,05933126 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03373357 0,05928857 ! ribosome assembly GO:0042255 18 14 0,000 0,03373357 0,05924595 ! cerebellum development GO:0021549 23 14 0,000 0,03373357 0,05920339 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03373357 0,05916089 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03373357 0,05911845 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03373357 0,05907607 ! response to gamma radiation GO:0010332 30 14 0,000 0,03373357 0,05903375 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03373357 0,05899149 ! NADP metabolic process GO:0006739 24 14 0,000 0,03373357 0,0589493 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03373357 0,05890716 ! oxygen transport GO:0015671 22 14 0,000 0,03373357 0,05886508 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03373357 0,05882307 ! male genitalia development GO:0030539 26 14 0,000 0,03373357 0,05878111 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03373357 0,05873921 ! regulation of axon extension GO:0030516 43 14 0,000 0,03373357 0,05869737 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03373357 0,0586556 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03373357 0,05861388 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03373357 0,05857222 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0360996 0,06263589 ! lactation GO:0007595 30 15 0,000 0,0360996 0,06259144 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,0360996 0,06254705 ! reproductive cellular process GO:0048610 22 15 0,000 0,0360996 0,06250272 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0360996 0,06245845 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0360996 0,06241425 ! superoxide anion generation GO:0042554 22 15 0,000 0,0360996 0,06237011 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0360996 0,06232603 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0360996 0,06228202 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0360996 0,06223806 ! copper ion transport GO:0006825 22 15 0,000 0,0360996 0,06219417 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0360996 0,06215034 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0360996 0,06210657 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0360996 0,06206287 ! sulfate transport GO:0008272 27 15 0,000 0,0360996 0,06201922 ! response to cAMP GO:0051591 25 15 0,000 0,0360996 0,06197564 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0360996 0,06193212 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0360996 0,06188866 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0360996 0,06184526 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0360996 0,06180192 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0360996 0,06175864 ! vesicle coating GO:0006901 38 15 0,000 0,0360996 0,06171542 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0360996 0,06167226 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0360996 0,06162916 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0360996 0,06158613 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0360996 0,06154315 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0360996 0,06150023 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0360996 0,06145738 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0360996 0,06141458 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0360996 0,06137184 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0360996 0,06132916 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0360996 0,06128654 ! histone deacetylation GO:0016575 24 15 0,000 0,0360996 0,06124398 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0360996 0,06120148 ! water homeostasis GO:0030104 28 15 0,000 0,0360996 0,06115904 ! cofactor transport GO:0051181 30 15 0,000 0,0360996 0,06111666 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0360996 0,06107433 ! muscle maintenance GO:0046716 26 15 0,000 0,0360996 0,06103207 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0360996 0,06098986 ! intestinal absorption GO:0050892 31 15 0,000 0,0360996 0,06094771 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0360996 0,06090562 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0360996 0,06086359 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0360996 0,06082161 ! cell killing GO:0001906 32 15 0,000 0,0360996 0,06077969 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0360996 0,06073783 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0360996 0,06069603 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0360996 0,06065429 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0360996 0,0606126 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0360996 0,06057097 ! actin filament polymerization GO:0030041 27 15 0,000 0,0360996 0,0605294 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0360996 0,06048788 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03845991 0,0643986 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03845991 0,0643545 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03845991 0,06431045 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03845991 0,06426646 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03845991 0,06422253 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03845991 0,06417866 ! bone remodeling GO:0046849 28 16 0,000 0,03845991 0,06413486 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03845991 0,06409111 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03845991 0,06404742 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03845991 0,06400379 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03845991 0,06396022 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03845991 0,06391671 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03845991 0,06387326 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03845991 0,06382987 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03845991 0,06378653 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03845991 0,06374326 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03845991 0,06370004 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03845991 0,06365689 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03845991 0,06361379 ! pituitary gland development GO:0021983 30 16 0,000 0,03845991 0,06357075 ! response to osmotic stress GO:0006970 27 16 0,000 0,03845991 0,06352776 ! lysosomal transport GO:0007041 31 16 0,000 0,03845991 0,06348484 ! fructose metabolic process GO:0006000 25 16 0,000 0,03845991 0,06344197 ! L-amino acid transport GO:0015807 33 16 0,000 0,03845991 0,06339917 ! stem cell development GO:0048864 46 16 0,000 0,03845991 0,06335642 GO:0019827|stem cell maintenance, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03845991 0,06331372 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03845991 0,06327109 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03845991 0,06322851 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03845991 0,06318599 ! axon cargo transport GO:0008088 46 16 0,000 0,03845991 0,06314352 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03845991 0,06310112 ! DNA replication initiation GO:0006270 28 16 0,000 0,03845991 0,06305877 ! neuron recognition GO:0008038 40 16 0,000 0,03845991 0,06301647 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03845991 0,06297424 ! tissue regeneration GO:0042246 27 16 0,000 0,03845991 0,06293206 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03845991 0,06288994 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03845991 0,06284787 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03845991 0,06280586 ! biomineral formation GO:0031214 22 16 0,000 0,03845991 0,0627639 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03845991 0,06272201 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03845991 0,06268016 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03845991 0,06263838 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03845991 0,06259664 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03845991 0,06255497 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03845991 0,06251335 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03845991 0,06247178 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03845991 0,06243028 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03845991 0,06238882 ! peptide hormone processing GO:0016486 27 16 0,000 0,03845991 0,06234742 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,0408145 0,06612058 ! metencephalon development GO:0022037 32 17 0,000 0,0408145 0,06607676 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,0408145 0,066033 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,0408145 0,0659893 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,0408145 0,06594566 ! filopodium assembly GO:0046847 42 17 0,000 0,0408145 0,06590207 ! gene silencing by RNA GO:0031047 38 17 0,000 0,0408145 0,06585854 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,0408145 0,06581507 ! glial cell development GO:0021782 28 17 0,000 0,0408145 0,06577166 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,0408145 0,0657283 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,0408145 0,065685 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,0408145 0,06564176 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,0408145 0,06559858 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,0408145 0,06555545 ! myoblast differentiation GO:0045445 50 17 0,000 0,0408145 0,06551238 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,0408145 0,06546936 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,0408145 0,0654264 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,0408145 0,0653835 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,0408145 0,06534065 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,0408145 0,06529786 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,0408145 0,06525513 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,0408145 0,06521245 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,0408145 0,06516983 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,0408145 0,06512726 ! membrane budding GO:0006900 42 17 0,000 0,0408145 0,06508475 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,0408145 0,06504229 ! regulation of protein binding GO:0043393 33 17 0,000 0,0408145 0,06499989 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,0408145 0,06495755 ! genitalia development GO:0048806 32 17 0,000 0,0408145 0,06491526 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,0408145 0,06487302 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,0408145 0,06483084 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,0408145 0,06478872 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,0408145 0,06474665 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,0408145 0,06470463 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,0408145 0,06466267 ! steroid catabolic process GO:0006706 34 17 0,000 0,0408145 0,06462076 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,0408145 0,06457891 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,0408145 0,06453711 ! gas transport GO:0015669 26 17 0,000 0,0408145 0,06449537 ! organic cation transport GO:0015695 32 17 0,000 0,0408145 0,06445368 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,0408145 0,06441204 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,0408145 0,06437046 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,0408145 0,06432893 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,0431634 0,06798722 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0431634 0,06794342 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0431634 0,06789967 ! limbic system development GO:0021761 40 18 0,000 0,0431634 0,06785597 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0431634 0,06781234 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0431634 0,06776875 ! adult walking behavior GO:0007628 36 18 0,000 0,0431634 0,06772523 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0431634 0,06768176 ! heart looping GO:0001947 34 18 0,000 0,0431634 0,06763835 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0431634 0,06759499 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0431634 0,06755169 ! centrosome cycle GO:0007098 26 18 0,000 0,0431634 0,06750844 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,0431634 0,06746525 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0431634 0,06742211 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,0431634 0,06737903 ! glycine metabolic process GO:0006544 30 18 0,000 0,0431634 0,067336 ! response to retinoic acid GO:0032526 31 18 0,000 0,0431634 0,06729303 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,0431634 0,06725012 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0431634 0,06720725 ! DNA integration GO:0015074 32 18 0,000 0,0431634 0,06716445 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0431634 0,06712169 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0431634 0,067079 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0431634 0,06703635 ! neural crest cell migration GO:0001755 41 18 0,000 0,0431634 0,06699376 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0431634 0,06695123 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0431634 0,06690874 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0431634 0,06686632 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0431634 0,06682394 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0431634 0,06678162 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0431634 0,06673936 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,0431634 0,06669714 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0431634 0,06665498 ! detection of bacterium GO:0016045 22 18 0,000 0,0431634 0,06661288 ! nerve development GO:0021675 34 18 0,000 0,0431634 0,06657082 ! defense response to virus GO:0051607 43 18 0,000 0,0431634 0,06652882 ! microspike assembly GO:0030035 46 18 0,000 0,0431634 0,06648687 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0431634 0,06644498 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,0431634 0,06640314 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04550661 0,0699639 ! positive regulation of translation GO:0045727 31 19 0,000 0,04550661 0,0699199 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04550661 0,06987595 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04550661 0,06983206 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04550661 0,06978822 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04550661 0,06974444 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04550661 0,06970071 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04550661 0,06965704 ! inositol metabolic process GO:0006020 33 19 0,000 0,04550661 0,06961342 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04550661 0,06956986 ! memory GO:0007613 34 19 0,000 0,04550661 0,06952635 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04550661 0,0694829 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04550661 0,0694395 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04550661 0,06939615 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04550661 0,06935286 ! cerebral cortex development GO:0021987 40 19 0,000 0,04550661 0,06930962 ! response to vitamin A GO:0033189 32 19 0,000 0,04550661 0,06926644 ! heme metabolic process GO:0042168 40 19 0,000 0,04550661 0,06922331 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04550661 0,06918023 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04550661 0,06913721 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04550661 0,06909424 ! response to fungus GO:0009620 26 19 0,000 0,04550661 0,06905133 ! peptide cross-linking GO:0018149 39 19 0,000 0,04550661 0,06900847 ! protein export from nucleus GO:0006611 40 19 0,000 0,04550661 0,06896566 ! heart process GO:0003015 32 19 0,000 0,04550661 0,0689229 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04550661 0,0688802 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04550661 0,06883755 ! cellular pigmentation GO:0033059 37 19 0,000 0,04550661 0,06879495 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04550661 0,0687524 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04550661 0,06870991 ! vitamin transport GO:0051180 31 19 0,000 0,04550661 0,06866747 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04550661 0,06862508 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04550661 0,06858275 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04550661 0,06854047 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04550661 0,06849824 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04550661 0,06845606 ! cilium assembly GO:0042384 38 19 0,000 0,04550661 0,06841393 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04550661 0,06837186 ! protein secretion GO:0009306 45 20 0,000 0,04784414 0,07183973 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04784414 0,0717956 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04784414 0,07175153 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04784414 0,07170751 ! skin development GO:0043588 42 20 0,000 0,04784414 0,07166354 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,04784414 0,07161963 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04784414 0,07157577 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04784414 0,07153197 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04784414 0,07148822 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04784414 0,07144452 ! response to vitamin GO:0033273 36 20 0,000 0,04784414 0,07140088 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04784414 0,07135729 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04784414 0,07131375 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04784414 0,07127027 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04784414 0,07122683 ! response to alkaloid GO:0043279 38 20 0,000 0,04784414 0,07118346 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04784414 0,07114013 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04784414 0,07109686 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04784414 0,07105364 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04784414 0,07101047 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04784414 0,07096736 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04784414 0,07092429 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04784414 0,07088128 ! body fluid secretion GO:0007589 33 20 0,000 0,04784414 0,07083832 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04784414 0,07079542 ! peptide secretion GO:0002790 38 20 0,000 0,04784414 0,07075256 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04784414 0,07070976 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04784414 0,07066701 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04784414 0,07062431 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04784414 0,07058166 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04784414 0,07053907 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04784414 0,07049652 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04784414 0,07045403 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04784414 0,07041159 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04784414 0,0703692 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04784414 0,07032686 ! regulation of glucose import GO:0046324 30 20 0,000 0,04784414 0,07028457 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04784414 0,07024233 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04784414 0,07020014 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04784414 0,070158 ! negative regulation of translation GO:0017148 32 20 0,000 0,04784414 0,07011592 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04784414 0,07007388 ! regulation of cell killing GO:0031341 46 21 0,000 0,05017602 0,07344518 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05017602 0,0734012 ! hormone secretion GO:0046879 39 21 0,000 0,05017602 0,07335728 ! lipid phosphorylation GO:0046834 43 21 0,000 0,05017602 0,0733134 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05017602 0,07326958 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05017602 0,07322581 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05017602 0,07318209 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05017602 0,07313843 ! ovarian follicle development GO:0001541 39 21 0,000 0,05017602 0,07309482 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05017602 0,07305126 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,05017602 0,07300775 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05017602 0,07296429 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,05017602 0,07292089 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05017602 0,07287753 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05017602 0,07283423 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05017602 0,07279098 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,05017602 0,07274778 ! sensory perception of pain GO:0019233 33 21 0,000 0,05017602 0,07270463 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05017602 0,07266153 ! diencephalon development GO:0021536 36 21 0,000 0,05017602 0,07261849 ! collagen fibril organization GO:0030199 62 21 0,000 0,05017602 0,07257549 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05017602 0,07253255 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,05017602 0,07248966 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,05017602 0,07244681 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05017602 0,07240402 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,05017602 0,07236128 ! collagen catabolic process GO:0030574 29 21 0,000 0,05017602 0,07231859 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05017602 0,07227595 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05017602 0,07223336 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05017602 0,07219082 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,05017602 0,07214833 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05250225 0,07544882 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05250225 0,07540446 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05250225 0,07536016 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05250225 0,07531591 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,05250225 0,07527171 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,05250225 0,07522756 ! microtubule-based transport GO:0010970 59 22 0,000 0,05250225 0,07518346 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,05250225 0,07513942 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,05250225 0,07509543 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,05250225 0,07505149 ! cellular response to starvation GO:0009267 37 22 0,000 0,05250225 0,0750076 ! vacuolar transport GO:0007034 41 22 0,000 0,05250225 0,07496376 ! fucose metabolic process GO:0006004 44 22 0,000 0,05250225 0,07491997 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05250225 0,07487623 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05250225 0,07483255 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,05250225 0,07478891 ! ureteric bud development GO:0001657 50 22 0,000 0,05250225 0,07474533 ! cell aging GO:0007569 48 22 0,000 0,05250225 0,0747018 ! stem cell differentiation GO:0048863 57 22 0,000 0,05250225 0,07465832 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,05250225 0,07461489 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,05250225 0,07457151 ! cytolysis GO:0019835 27 22 0,000 0,05250225 0,07452818 ! renal system process GO:0003014 42 22 0,000 0,05250225 0,07448489 ! vasodilation GO:0042311 40 22 0,000 0,05250225 0,07444167 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,05250225 0,07439849 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,05250225 0,07435536 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,05250225 0,07431228 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05250225 0,07426925 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05250225 0,07422627 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,05250225 0,07418334 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,05250225 0,07414046 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05250225 0,07409763 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05250225 0,07405484 ! sarcomere organization GO:0045214 32 22 0,000 0,05250225 0,07401211 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,05250225 0,07396943 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,05250225 0,07392679 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,05250225 0,07388421 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05250225 0,07384167 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05250225 0,07379919 ! gut development GO:0048565 44 22 0,000 0,05250225 0,07375675 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,05250225 0,07371436 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,05250225 0,07367202 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05250225 0,07362973 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,05482285 0,07684005 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05482285 0,07679599 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05482285 0,07675198 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05482285 0,07670802 ! gluconeogenesis GO:0006094 38 23 0,000 0,05482285 0,07666412 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05482285 0,07662026 ! viral genome replication GO:0019079 44 23 0,000 0,05482285 0,07657645 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05482285 0,07653269 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05482285 0,07648898 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,05482285 0,07644533 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05482285 0,07640172 ! regeneration GO:0031099 42 23 0,000 0,05482285 0,07635816 ! axis specification GO:0009798 43 23 0,000 0,05482285 0,07631465 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,05482285 0,07627119 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05482285 0,07622778 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05482285 0,07618442 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05482285 0,07614111 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05482285 0,07609785 ! peroxisome organization GO:0007031 43 23 0,000 0,05482285 0,07605463 ! lysosome organization GO:0007040 47 23 0,000 0,05482285 0,07601147 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05482285 0,07596836 ! vesicle targeting GO:0006903 49 23 0,000 0,05482285 0,07592529 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,05482285 0,07588227 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05482285 0,0758393 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05482285 0,07579638 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05482285 0,07575351 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05482285 0,07571069 ! DNA modification GO:0006304 36 23 0,000 0,05482285 0,07566792 ! fatty acid transport GO:0015908 47 23 0,000 0,05482285 0,07562519 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05482285 0,07558251 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05482285 0,07553988 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05482285 0,0754973 ! hormone transport GO:0009914 41 23 0,000 0,05482285 0,07545477 ! cell-cell recognition GO:0009988 28 23 0,000 0,05482285 0,07541228 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05482285 0,07536984 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05482285 0,07532745 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05482285 0,07528511 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05713783 0,07842006 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05713783 0,07837603 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,05713783 0,07833205 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,05713783 0,07828811 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05713783 0,07824423 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05713783 0,0782004 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05713783 0,07815661 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05713783 0,07811288 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05713783 0,07806919 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05713783 0,07802555 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05713783 0,07798196 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,05713783 0,07793842 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05713783 0,07789493 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05713783 0,07785148 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05713783 0,07780809 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05713783 0,07776474 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05713783 0,07772144 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05713783 0,07767819 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05713783 0,07763499 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05713783 0,07759183 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,05713783 0,07754873 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05713783 0,07750567 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05713783 0,07746266 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05713783 0,07741969 ! pallium development GO:0021543 56 24 0,000 0,05713783 0,07737678 ! oogenesis GO:0048477 44 24 0,000 0,05713783 0,07733391 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05713783 0,07729109 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05713783 0,07724832 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,05713783 0,07720559 ! platelet activation GO:0030168 41 24 0,000 0,05713783 0,07716291 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05713783 0,07712028 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05713783 0,0770777 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05713783 0,07703516 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05713783 0,07699267 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05713783 0,07695023 ! regulation of amine transport GO:0051952 41 24 0,000 0,05713783 0,07690783 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,05713783 0,07686548 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0594472 0,07992818 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0594472 0,07988422 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0594472 0,0798403 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0594472 0,07979644 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0594472 0,07975262 ! phototransduction GO:0007602 37 25 0,000 0,0594472 0,07970884 ! keratinization GO:0031424 37 25 0,000 0,0594472 0,07966512 ! vasculogenesis GO:0001570 49 25 0,000 0,0594472 0,07962144 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0594472 0,07957781 ! vacuole organization GO:0007033 49 25 0,000 0,0594472 0,07953423 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0594472 0,0794907 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0594472 0,07944722 ! chromosome condensation GO:0030261 48 25 0,000 0,0594472 0,07940378 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0594472 0,07936039 ! regulation of behavior GO:0050795 48 25 0,000 0,0594472 0,07931705 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0594472 0,07927375 ! interaction with host GO:0051701 66 25 0,000 0,0594472 0,0792305 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0594472 0,0791873 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0594472 0,07914415 ! immunoglobulin production GO:0002377 62 25 0,000 0,0594472 0,07910104 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0594472 0,07905798 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0594472 0,07901497 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0594472 0,078972 ! liver development GO:0001889 55 25 0,000 0,0594472 0,07892908 ! protein tetramerization GO:0051262 57 25 0,000 0,0594472 0,07888621 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,06175098 0,08189884 ! myelination GO:0042552 50 26 0,000 0,06175098 0,0818544 ! initiation of viral infection GO:0019059 60 26 0,000 0,06175098 0,08181001 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,06175098 0,08176567 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,06175098 0,08172137 ! molting cycle process GO:0022404 52 26 0,000 0,06175098 0,08167713 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,06175098 0,08163293 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,06175098 0,08158878 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,06175098 0,08154468 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,06175098 0,08150062 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,06175098 0,08145662 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,06175098 0,08141266 ! digestive system process GO:0022600 49 26 0,000 0,06175098 0,08136875 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,06175098 0,08132488 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,06175098 0,08128106 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,06175098 0,08123729 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,06175098 0,08119357 ! osteoblast differentiation GO:0001649 63 26 0,000 0,06175098 0,0811499 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,06175098 0,08110627 ! neural crest cell development GO:0014032 59 26 0,000 0,06175098 0,08106268 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,06175098 0,08101915 ! negative regulation of cell development GO:0010721 83 26 0,000 0,06175098 0,08097566 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,06175098 0,08093222 ! pentose metabolic process GO:0019321 43 26 0,000 0,06175098 0,08088882 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,06175098 0,08084547 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,06175098 0,08080217 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,06175098 0,08075892 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,06175098 0,08071571 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,06175098 0,08067254 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,06175098 0,08062943 ! blastocyst development GO:0001824 50 26 0,000 0,06175098 0,08058635 ! telomere organization GO:0032200 46 26 0,000 0,06175098 0,08054333 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,06175098 0,08050035 ! neural tube closure GO:0001843 58 26 0,000 0,06175098 0,08045742 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,06175098 0,08041453 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,06175098 0,08037169 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,06175098 0,08032889 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,06404919 0,08327417 ! embryonic pattern specification GO:0009880 49 27 0,000 0,06404919 0,08322988 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,06404919 0,08318563 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,06404919 0,08314143 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,06404919 0,08309728 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,06404919 0,08305317 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,06404919 0,08300911 ! iron ion transport GO:0006826 65 27 0,000 0,06404919 0,0829651 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,06404919 0,08292113 ! superoxide metabolic process GO:0006801 41 27 0,000 0,06404919 0,08287721 ! tube lumen formation GO:0035148 59 27 0,000 0,06404919 0,08283334 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,06404919 0,08278951 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,06404919 0,08274573 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,06404919 0,08270199 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,06404919 0,08265831 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,06404919 0,08261466 ! response to starvation GO:0042594 47 27 0,000 0,06404919 0,08257107 ! response to toxin GO:0009636 49 27 0,000 0,06404919 0,08252752 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,06404919 0,08248401 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,06404919 0,08244055 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,06404919 0,08239714 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,06404919 0,08235377 ! leukocyte proliferation GO:0070661 59 27 0,000 0,06404919 0,08231045 GO:0032943|mononuclear cell proliferation, ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,06634183 0,08521193 ! neuron fate commitment GO:0048663 52 28 0,000 0,06634183 0,08516715 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,06634183 0,08512242 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,06634183 0,08507774 ! protein amino acid acylation GO:0043543 59 28 0,000 0,06634183 0,0850331 ! vesicle docking GO:0048278 55 28 0,000 0,06634183 0,08498851 ! circadian rhythm GO:0007623 56 28 0,000 0,06634183 0,08494397 ! dendrite development GO:0016358 67 28 0,000 0,06634183 0,08489947 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,06634183 0,08485502 ! fat cell differentiation GO:0045444 57 28 0,000 0,06634183 0,08481062 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,06634183 0,08476626 ! sperm motility GO:0030317 37 28 0,000 0,06634183 0,08472195 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,06634183 0,08467769 ! base-excision repair GO:0006284 41 28 0,000 0,06634183 0,08463347 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,06634183 0,0845893 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,06634183 0,08454517 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,06634183 0,08450109 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,06634183 0,08445706 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,06634183 0,08441307 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,06634183 0,08436913 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,06634183 0,08432523 ! glutathione metabolic process GO:0006749 42 28 0,000 0,06634183 0,08428138 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,06634183 0,08423757 ! lipid oxidation GO:0034440 48 28 0,000 0,06634183 0,08419381 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,06634183 0,0841501 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,06634183 0,08410643 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,06862892 0,08696082 ! translational initiation GO:0006413 66 29 0,000 0,06862892 0,08691573 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06862892 0,0868707 ! catechol metabolic process GO:0009712 55 29 0,000 0,06862892 0,08682571 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,06862892 0,08678077 ! autophagy GO:0006914 47 29 0,000 0,06862892 0,08673588 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06862892 0,08669103 ! primary neural tube formation GO:0014020 61 29 0,000 0,06862892 0,08664623 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06862892 0,08660147 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06862892 0,08655676 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06862892 0,0865121 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,06862892 0,08646748 ! somitogenesis GO:0001756 52 29 0,000 0,06862892 0,08642291 ! synaptogenesis GO:0007416 46 29 0,000 0,06862892 0,08637839 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06862892 0,08633391 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06862892 0,08628948 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06862892 0,08624509 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06862892 0,08620075 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,07091047 0,0890207 ! phenol metabolic process GO:0018958 56 30 0,000 0,07091047 0,08897498 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,07091047 0,0889293 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,07091047 0,08888367 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,07091047 0,08883809 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,07091047 0,08879256 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,07091047 0,08874707 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,07091047 0,08870163 ! acute-phase response GO:0006953 50 30 0,000 0,07091047 0,08865623 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,07091047 0,08861089 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,07091047 0,08856558 ! myofibril assembly GO:0030239 50 30 0,000 0,07091047 0,08852033 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,07091047 0,08847512 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,07091047 0,08842995 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,07091047 0,08838484 ! cell fate determination GO:0001709 64 30 0,000 0,07091047 0,08833977 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,07091047 0,08829474 ! phospholipid transport GO:0015914 65 30 0,000 0,07091047 0,08824976 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,07091047 0,08820483 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,07091047 0,08815994 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,07091047 0,0881151 ! tissue homeostasis GO:0001894 50 30 0,000 0,07091047 0,0880703 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,07091047 0,08802555 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,0731865 0,09080478 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,0731865 0,09075869 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,0731865 0,09071264 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,0731865 0,09066664 ! regulation of innate immune response GO:0045088 57 31 0,000 0,0731865 0,09062069 ! ovulation cycle process GO:0022602 55 31 0,000 0,0731865 0,09057478 ! peptide transport GO:0015833 60 31 0,000 0,0731865 0,09052892 ! male gonad development GO:0008584 56 31 0,000 0,0731865 0,0904831 ! iron ion homeostasis GO:0055072 60 31 0,000 0,0731865 0,09043734 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,0731865 0,09039161 ! detection of light stimulus GO:0009583 44 31 0,000 0,0731865 0,09034594 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,0731865 0,09030031 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,0731865 0,09025473 ! natural killer cell activation GO:0030101 50 31 0,000 0,0731865 0,09020919 ! ensheathment of neurons GO:0007272 64 31 0,000 0,0731865 0,0901637 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,0731865 0,09011825 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,0731865 0,09007285 ! eye morphogenesis GO:0048592 65 31 0,000 0,0731865 0,0900275 ! response to heat GO:0009408 54 31 0,000 0,0731865 0,08998219 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,0731865 0,08993693 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,07545701 0,09268048 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,07545701 0,09263391 ! collagen metabolic process GO:0032963 49 32 0,000 0,07545701 0,09258738 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,07545701 0,0925409 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,07545701 0,09249447 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,07545701 0,09244808 ! metanephros development GO:0001656 81 32 0,000 0,07545701 0,09240174 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,07545701 0,09235545 ! muscle cell development GO:0055001 52 32 0,000 0,07545701 0,0923092 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,07545701 0,092263 ! ovulation cycle GO:0042698 57 32 0,000 0,07545701 0,09221685 ! peripheral nervous system development GO:0007422 68 32 0,000 0,07545701 0,09217074 ! BMP signaling pathway GO:0030509 71 32 0,000 0,07545701 0,09212468 ! hindbrain development GO:0030902 65 32 0,000 0,07545701 0,09207866 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,07545701 0,09203269 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,07545701 0,09198677 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,07545701 0,09194089 ! gene silencing GO:0016458 71 32 0,000 0,07545701 0,09189505 ! regulation of pH GO:0006885 56 33 0,000 0,07772203 0,09460633 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07772203 0,09455922 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,07772203 0,09451215 GO:0055092|sterol homeostasis, ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,07772203 0,09446513 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,07772203 0,09441816 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,07772203 0,09437123 ! response to ionizing radiation GO:0010212 74 33 0,000 0,07772203 0,09432435 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,07772203 0,09427751 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,07772203 0,09423073 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,07772203 0,09418398 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07772203 0,09413729 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07772203 0,09409064 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,07772203 0,09404404 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07998156 0,09673017 ! glial cell differentiation GO:0010001 67 34 0,000 0,07998156 0,09668231 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,07998156 0,09663449 ! cholesterol transport GO:0030301 62 34 0,000 0,07998156 0,09658673 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07998156 0,096539 ! spliceosome assembly GO:0000245 75 34 0,000 0,07998156 0,09649133 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07998156 0,0964437 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,07998156 0,09639613 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,07998156 0,09634859 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,07998156 0,09630111 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,07998156 0,09625367 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,08223562 0,09891758 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,08223562 0,0988689 ! negative regulation of secretion GO:0051048 68 35 0,000 0,08223562 0,09882027 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,08223562 0,09877169 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,08223562 0,09872315 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,08223562 0,09867466 ! membrane docking GO:0022406 69 35 0,000 0,08223562 0,09862622 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,08223562 0,09857783 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,08223562 0,09852948 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,08223562 0,09848118 ! ceramide metabolic process GO:0006672 72 35 0,000 0,08223562 0,09843293 ! telencephalon development GO:0021537 81 35 0,000 0,08223562 0,09838473 ! sterol transport GO:0015918 63 35 0,000 0,08223562 0,09833657 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,08223562 0,09828846 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,08223562 0,0982404 ! placenta development GO:0001890 53 35 0,000 0,08223562 0,09819238 ! vesicle localization GO:0051648 70 35 0,000 0,08223562 0,09814441 ! regulation of muscle development GO:0048634 82 36 0,000 0,08448421 0,10077878 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,08448421 0,10072959 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,08448421 0,10068046 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,08448421 0,10063137 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,08448421 0,10058233 ! positive regulation of cell development GO:0010720 85 36 0,000 0,08448421 0,10053334 ! protein targeting to membrane GO:0006612 75 36 0,000 0,08448421 0,10048439 ! regulation of proteolysis GO:0030162 77 36 0,000 0,08448421 0,10043549 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,08448421 0,10038664 ! aerobic respiration GO:0009060 56 36 0,000 0,08448421 0,10033784 ! cytokine production GO:0001816 68 36 0,000 0,08448421 0,10028908 ! embryonic organ development GO:0048568 67 36 0,000 0,08448421 0,10024038 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,08448421 0,10019172 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,08448421 0,1001431 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,08672737 0,10275216 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,08672737 0,10270236 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,08672737 0,1026526 ! sister chromatid segregation GO:0000819 65 37 0,000 0,08672737 0,10260289 ! odontogenesis GO:0042476 74 37 0,000 0,08672737 0,10255322 ! actomyosin structure organization GO:0031032 68 37 0,000 0,08672737 0,10250361 ! tissue remodeling GO:0048771 78 37 0,000 0,08672737 0,10245404 ! female gonad development GO:0008585 71 37 0,000 0,08672737 0,10240452 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,08672737 0,10235505 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,08672737 0,10230563 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,08672737 0,10225625 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,08896509 0,10484405 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,08896509 0,1047935 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,08896509 0,10474299 ! organic anion transport GO:0015711 82 38 0,000 0,08896509 0,10469254 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,08896509 0,10464213 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,08896509 0,10459178 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,08896509 0,10454147 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,08896509 0,10449121 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,08896509 0,10444099 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,08896509 0,10439083 ! spermatid development GO:0007286 69 38 0,000 0,08896509 0,10434071 ! glycogen metabolic process GO:0005977 63 38 0,000 0,08896509 0,10429065 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,08896509 0,10424063 ! neural tube formation GO:0001841 79 38 0,000 0,08896509 0,10419066 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,09119739 0,10675382 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,09119739 0,10670269 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,09119739 0,10665161 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,09119739 0,10660058 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,09119739 0,1065496 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,09119739 0,10649867 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,09119739 0,10644779 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,09119739 0,10639695 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,09119739 0,10634617 ! glucan metabolic process GO:0044042 64 39 0,000 0,09119739 0,10629543 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,09342428 0,10883906 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,09342428 0,10878719 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,09342428 0,10873536 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,09342428 0,10868358 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,09342428 0,10863185 ! lipid homeostasis GO:0055088 75 40 0,000 0,09342428 0,10858017 ! mismatch repair GO:0006298 58 40 0,000 0,09342428 0,10852854 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,09342428 0,10847696 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,09342428 0,10842542 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,09342428 0,10837394 ! RNA export from nucleus GO:0006405 61 41 0,000 0,09564578 0,11089826 ! mRNA catabolic process GO:0006402 79 41 0,000 0,09564578 0,11084565 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,09564578 0,1107931 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,09564578 0,11074059 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,09564578 0,11068813 ! gliogenesis GO:0042063 91 41 0,000 0,09564578 0,11063572 ! feeding behavior GO:0007631 69 41 0,000 0,09564578 0,11058336 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,09564578 0,11053105 ! mesenchymal cell development GO:0014031 94 41 0,000 0,09564578 0,11047879 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,09564578 0,11042658 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,09564578 0,11037442 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,09564578 0,1103223 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,09564578 0,11027024 ! RNA modification GO:0009451 64 41 0,000 0,09564578 0,11021823 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,0978619 0,11271882 ! ear morphogenesis GO:0042471 64 42 0,000 0,0978619 0,1126657 ! organic ether metabolic process GO:0018904 59 42 0,000 0,0978619 0,11261263 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,0978619 0,11255961 ! T cell differentiation GO:0030217 93 42 0,000 0,0978619 0,11250664 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,0978619 0,11245372 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,0978619 0,11240085 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,0978619 0,11234803 ! regulation of protein secretion GO:0050708 77 42 0,000 0,0978619 0,11229526 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,0978619 0,11224254 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,0978619 0,11218987 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,10007265 0,11467048 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,10007265 0,11461672 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,10007265 0,11456301 ! regulation of tube size GO:0035150 76 43 0,000 0,10007265 0,11450935 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,10007265 0,11445575 ! glucose transport GO:0015758 66 43 0,000 0,10007265 0,11440219 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,10007265 0,11434868 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,10007265 0,11429522 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,10007265 0,11424181 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,10007265 0,11418845 ! segmentation GO:0035282 78 43 0,000 0,10007265 0,11413514 ! ion transmembrane transport GO:0034220 79 43 0,000 0,10007265 0,11408188 ! neuron migration GO:0001764 85 43 0,000 0,10007265 0,11402867 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,10227804 0,1164873 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,10227804 0,11643301 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,10227804 0,11637878 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,10227804 0,1163246 ! hexose transport GO:0008645 68 44 0,000 0,10227804 0,11627047 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,10227804 0,1162164 ! striated muscle contraction GO:0006941 85 44 0,000 0,10227804 0,11616237 ! phagocytosis GO:0006909 105 44 0,000 0,10227804 0,11610839 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,10227804 0,11605446 ! double-strand break repair GO:0006302 85 44 0,000 0,10227804 0,11600058 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,10447809 0,11844082 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,10447809 0,11838589 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,10447809 0,118331 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,10447809 0,11827617 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,10447809 0,11822139 ! biopolymer methylation GO:0043414 91 45 0,000 0,10447809 0,11816665 ! B cell differentiation GO:0030183 124 45 0,000 0,10447809 0,11811197 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,10447809 0,11805734 ! female gamete generation GO:0007292 71 45 0,000 0,10447809 0,11800276 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,10447809 0,11794823 ! polyol metabolic process GO:0019751 77 45 0,000 0,10447809 0,11789375 ! developmental growth GO:0048589 88 45 0,000 0,10447809 0,11783932 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,10667281 0,1202592 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,10667281 0,12020373 ! glycolysis GO:0006096 71 46 0,000 0,10667281 0,12014831 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,10667281 0,12009294 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,10667281 0,12003762 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,10667281 0,11998236 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,10667281 0,11992714 ! cell growth GO:0016049 90 46 0,000 0,10667281 0,11987198 ! neural tube development GO:0021915 91 47 0,000 0,10886222 0,12227604 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,10886222 0,12221985 ! response to insulin stimulus GO:0032868 98 47 0,000 0,10886222 0,12216371 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,11104631 0,12455746 ! positive regulation of defense response GO:0031349 88 48 0,000 0,11104631 0,1245003 ! mitochondrial transport GO:0006839 94 48 0,000 0,11104631 0,12444319 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,11104631 0,12438613 ! cellular component disassembly GO:0022411 89 48 0,000 0,11104631 0,12432912 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,11104631 0,12427217 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,11104631 0,12421527 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,11104631 0,12415842 ! male sex differentiation GO:0046661 93 48 0,000 0,11104631 0,12410162 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,11104631 0,12404488 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,11104631 0,12398818 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,11104631 0,12393154 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,11104631 0,12387495 ! methylation GO:0032259 97 48 0,000 0,11104631 0,12381842 ! response to calcium ion GO:0051592 94 49 0,000 0,11322512 0,12619023 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,11322512 0,12613268 ! JNK cascade GO:0007254 106 49 0,000 0,11322512 0,12607519 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,11322512 0,12601776 ! protein homooligomerization GO:0051260 84 49 0,000 0,11322512 0,12596037 ! regulation of ion transport GO:0043269 86 50 0,000 0,11539865 0,12831994 ! endocrine system development GO:0035270 109 50 0,000 0,11539865 0,12826156 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,11539865 0,12820323 ! activation of caspase activity GO:0006919 95 50 0,000 0,11539865 0,12814496 ! regulation of ossification GO:0030278 123 50 0,000 0,11539865 0,12808674 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,11539865 0,12802857 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,11539865 0,12797045 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,11539865 0,12791239 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,11539865 0,12785438 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,11756691 0,13019763 ! viral infectious cycle GO:0019058 104 51 0,000 0,11756691 0,13013864 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,11756691 0,1300797 ! peptide metabolic process GO:0006518 80 51 0,000 0,11756691 0,13002081 ! response to temperature stimulus GO:0009266 84 51 0,000 0,11756691 0,12996198 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,11756691 0,1299032 ! positive regulation of binding GO:0051099 88 52 0,000 0,11972992 0,13223337 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,11972992 0,13217361 ! Notch signaling pathway GO:0007219 111 52 0,000 0,11972992 0,13211391 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,11972992 0,13205427 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,11972992 0,13199468 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,11972992 0,13193514 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,11972992 0,13187566 ! excretion GO:0007588 87 52 0,000 0,11972992 0,13181623 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,11972992 0,13175685 ! histone modification GO:0016570 104 52 0,000 0,11972992 0,13169753 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,11972992 0,13163826 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,11972992 0,13157904 ! amino acid activation GO:0043038 98 52 0,000 0,11972992 0,13151988 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,12188769 0,13382995 ! positive regulation of growth GO:0045927 96 53 0,000 0,12188769 0,13376983 ! inner ear development GO:0048839 89 53 0,000 0,12188769 0,13370976 ! chromatin remodeling GO:0006338 122 53 0,000 0,12188769 0,13364974 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,12188769 0,13358978 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,12188769 0,13352988 ! vesicle organization GO:0016050 127 53 0,000 0,12188769 0,13347003 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,12188769 0,13341023 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,12188769 0,13335048 ! cartilage development GO:0051216 99 53 0,000 0,12188769 0,13329079 ! synapse organization GO:0050808 102 53 0,000 0,12188769 0,13323115 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,12404023 0,13552338 ! regulation of translational initiation GO:0006446 87 54 0,000 0,12404023 0,1354628 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,12404023 0,13540227 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,12404023 0,1353418 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,12404023 0,13528138 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,12404023 0,13522101 ! covalent chromatin modification GO:0016569 115 54 0,000 0,12404023 0,1351607 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,12404023 0,13510044 ! RNA catabolic process GO:0006401 103 55 0,000 0,12618755 0,13737798 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,12618755 0,13731679 ! cell recognition GO:0008037 98 55 0,000 0,12618755 0,13725565 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,12618755 0,13719457 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,12618755 0,13713354 ! response to UV GO:0009411 120 55 0,000 0,12618755 0,13707256 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,12832967 0,13933751 ! glucose catabolic process GO:0006007 88 56 0,000 0,12832967 0,13927561 ! regulation of DNA replication GO:0006275 105 56 0,000 0,12832967 0,13921376 ! RNA elongation GO:0006354 90 56 0,000 0,12832967 0,13915197 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,1304666 0,14140635 ! chloride transport GO:0006821 102 57 0,000 0,1304666 0,14134364 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,1304666 0,14128099 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,1304666 0,14121839 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 0,000 0,1304666 0,14115585 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,1304666 0,14109336 ! regulation of actin filament length GO:0030832 118 58 0,000 0,13259835 0,1433353 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,13259835 0,1432719 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,13259835 0,14320856 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,13259835 0,14314528 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,13259835 0,14308206 ! aging GO:0007568 112 58 0,000 0,13259835 0,14301888 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,13259835 0,14295577 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,13259835 0,14289271 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,13259835 0,14282971 ! nuclear export GO:0051168 110 59 0,000 0,13472494 0,14505642 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,13684637 0,14727563 ! lipid modification GO:0030258 112 60 0,000 0,13684637 0,14721078 ! DNA catabolic process GO:0006308 94 60 0,000 0,13684637 0,14714598 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,13684637 0,14708125 ! kidney development GO:0001822 133 60 0,000 0,13684637 0,14701657 ! positive regulation of secretion GO:0051047 110 61 0,000 0,13896265 0,14922451 ! regulation of cellular component size GO:0032535 125 61 0,000 0,13896265 0,14915895 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,13896265 0,14909344 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,13896265 0,14902799 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,13896265 0,1489626 ! regulation of heart contraction GO:0008016 123 61 0,000 0,13896265 0,14889726 ! camera-type eye development GO:0043010 126 61 0,000 0,13896265 0,14883199 ! proton transport GO:0015992 117 61 0,000 0,13896265 0,14876677 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,13896265 0,1487016 ! viral reproductive process GO:0022415 132 62 0,000 0,14107381 0,15089462 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,14107381 0,15082859 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,14107381 0,15076261 ! tRNA processing GO:0008033 102 62 0,000 0,14107381 0,15069669 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,14107381 0,15063082 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,14317985 0,15281275 ! regulation of mitosis GO:0007088 112 63 0,000 0,14317985 0,15274602 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,14317985 0,15267935 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,14317985 0,15261273 ! hydrogen transport GO:0006818 121 64 0,000 0,14528079 0,15478455 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,14528079 0,15471708 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,14528079 0,15464966 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,14528079 0,15458231 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,14737664 0,15674407 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,14737664 0,15667586 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,14737664 0,15660771 GO:0048609|reproductive process in a multicellular organism, ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,14737664 0,15653962 ! ear development GO:0043583 114 66 0,000 0,1494674 0,15869138 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,1494674 0,15862244 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,1494674 0,15855356 ! gonad development GO:0008406 115 66 0,000 0,1494674 0,15848475 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,1494674 0,15841599 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,1515531 0,1605569 ! activation of MAPK activity GO:0000187 124 67 0,000 0,1515531 0,16048731 ! chromosome segregation GO:0007059 127 67 0,000 0,1515531 0,16041777 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,1515531 0,1603483 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,1515531 0,16027888 ! secondary metabolic process GO:0019748 125 67 0,000 0,1515531 0,16020953 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,15363374 0,16233876 ! hexose catabolic process GO:0019320 113 68 0,000 0,15363374 0,16226858 ! extracellular matrix organization GO:0030198 146 68 0,000 0,15363374 0,16219845 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,15363374 0,16212839 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,15363374 0,16205839 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,15363374 0,16198844 ! viral reproduction GO:0016032 142 68 0,000 0,15363374 0,16191856 ! adaptive immune response GO:0002250 126 68 0,000 0,15363374 0,16184874 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,15363374 0,16177897 ! cell projection assembly GO:0030031 138 68 0,000 0,15363374 0,16170927 ! negative regulation of cell size GO:0045792 144 69 0,000 0,15570933 0,16382339 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,15570933 0,16375286 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,15570933 0,1636824 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,15570933 0,163612 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,15570933 0,16354166 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,15570933 0,16347138 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,15570933 0,16340116 ! single fertilization GO:0007338 83 69 0,000 0,15570933 0,163331 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,1577799 0,16543189 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1577799 0,16536091 ! germ cell development GO:0007281 133 70 0,000 0,1577799 0,16529001 ! activation of immune response GO:0002253 120 70 0,000 0,1577799 0,16521916 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,1577799 0,16514837 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,15984544 0,16723872 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,15984544 0,16716713 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,15984544 0,1670956 ! carbohydrate transport GO:0008643 114 72 0,000 0,16190598 0,16917721 ! B cell activation GO:0042113 179 72 0,000 0,16190598 0,16910488 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,16190598 0,16903261 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,16190598 0,16896041 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,16190598 0,16888826 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,16190598 0,16881618 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,16190598 0,16874416 ! humoral immune response GO:0006959 115 73 0,000 0,16396152 0,17081365 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,16396152 0,17074084 ! regulation of immune effector process GO:0002697 156 73 0,000 0,16396152 0,17066809 ! acute inflammatory response GO:0002526 118 74 0,000 0,16601208 0,17272892 ! amino acid transport GO:0006865 148 74 0,000 0,16601208 0,17265539 ! regulation of caspase activity GO:0043281 136 74 0,000 0,16601208 0,17258192 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,16601208 0,17250851 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,16601208 0,17243517 ! transition metal ion transport GO:0000041 143 75 0,000 0,16805767 0,17448571 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,16805767 0,17441159 ! eye development GO:0001654 155 75 0,000 0,16805767 0,17433753 ! axon guidance GO:0007411 162 75 0,000 0,16805767 0,17426353 ! rhythmic process GO:0048511 142 75 0,000 0,16805767 0,1741896 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,17009829 0,17622991 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,17009829 0,17615521 ! regulation of blood pressure GO:0008217 134 76 0,000 0,17009829 0,17608056 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,17009829 0,17600599 ! amine catabolic process GO:0009310 136 77 0,000 0,17213397 0,17803696 ! neurotransmitter transport GO:0006836 142 77 0,000 0,17213397 0,17796161 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,17213397 0,17788633 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,17213397 0,17781112 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,17213397 0,17773597 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,17213397 0,17766088 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,17213397 0,17758585 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,17416472 0,17960507 ! antigen processing and presentation GO:0019882 117 78 0,000 0,17416472 0,17952928 ! fertilization GO:0009566 99 78 0,000 0,17416472 0,17945356 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,17416472 0,17937791 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,17619053 0,18138789 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,17619053 0,18131149 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,17619053 0,18123515 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,17619053 0,18115887 ! protein oligomerization GO:0051259 149 79 0,000 0,17619053 0,18108266 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,17619053 0,18100651 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,17821144 0,18300569 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,17821144 0,1829288 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,17821144 0,18285197 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,17821144 0,18277521 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,18022744 0,18476527 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,18022744 0,18468777 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,18223856 0,18667036 ! protein import into nucleus GO:0006606 174 82 0,000 0,18223856 0,18659212 ! exocytosis GO:0006887 153 83 0,000 0,1842448 0,18856726 ! response to drug GO:0042493 149 83 0,000 0,1842448 0,18848829 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,1842448 0,1884094 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,1842448 0,18833056 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 0,000 0,1842448 0,1882518 ! inorganic anion transport GO:0015698 156 83 0,000 0,1842448 0,1881731 ! response to metal ion GO:0010038 158 84 0,000 0,18624617 0,19013765 ! response to nutrient GO:0007584 135 84 0,000 0,18624617 0,19005823 ! digestion GO:0007586 130 84 0,000 0,18624617 0,18997887 ! regulation of ligase activity GO:0051340 147 84 0,000 0,18624617 0,18989958 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,18824269 0,19185519 ! negative regulation of growth GO:0045926 168 85 0,000 0,18824269 0,19177519 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,18824269 0,19169525 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,18824269 0,19161537 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,19023437 0,19356208 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,19222122 0,19550226 ! mitochondrion organization GO:0007005 159 87 0,000 0,19222122 0,1954209 ! alcohol catabolic process GO:0046164 142 87 0,000 0,19222122 0,19533961 ! nucleosome assembly GO:0006334 126 87 0,000 0,19222122 0,19525839 ! cellular respiration GO:0045333 143 88 0,000 0,19420324 0,19718974 ! amine biosynthetic process GO:0009309 146 88 0,000 0,19420324 0,19710782 ! sensory perception of smell GO:0007608 117 88 0,000 0,19420324 0,19702597 ! chromatin assembly GO:0031497 128 88 0,000 0,19420324 0,19694418 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,19420324 0,19686246 ! cellular defense response GO:0006968 123 89 0,000 0,19618046 0,19878427 ! protein localization in nucleus GO:0034504 192 89 0,000 0,19618046 0,19870185 ! response to inorganic substance GO:0010035 173 90 0,000 0,19815289 0,20061646 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,19815289 0,20053335 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,19815289 0,20045031 ! response to unfolded protein GO:0006986 139 90 0,000 0,19815289 0,20036735 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,19815289 0,20028445 ! ossification GO:0001503 205 91 0,000 0,20012053 0,2021896 ! defense response to bacterium GO:0042742 112 91 0,000 0,20012053 0,20210601 ! bone development GO:0060348 206 92 0,000 0,20208339 0,20400402 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,20208339 0,20391976 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,20208339 0,20383556 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,2040415 0,20572571 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,2040415 0,20564084 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,2040415 0,20555603 ! vitamin metabolic process GO:0006766 153 93 0,000 0,2040415 0,2054713 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,20599486 0,20735288 ! female pregnancy GO:0007565 166 94 0,000 0,20599486 0,20726748 ! sterol metabolic process GO:0016125 166 94 0,000 0,20599486 0,20718215 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,20599486 0,20709689 ! regulation of defense response GO:0031347 171 95 0,000 0,20794347 0,20896993 ! nucleosome organization GO:0034728 143 95 0,000 0,20794347 0,20888401 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,20794347 0,20879815 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,20794347 0,20871237 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,20794347 0,20862665 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,20794347 0,20854101 ! response to protein stimulus GO:0051789 158 96 0,000 0,20988736 0,21040411 ! regulation of T cell activation GO:0050863 175 96 0,000 0,20988736 0,21031781 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,21182653 0,21217393 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,21182653 0,21208698 ! transcription initiation GO:0006352 171 97 0,000 0,21182653 0,21200009 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,213761 0,21384854 ! positive regulation of immune response GO:0050778 175 100 0,000 0,21761587 0,21761587