pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6880-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cell motion GO:0051270 79 79 7,000 7,666E-08 1,413E-04 ! positive regulation of cell motion GO:0051272 39 39 5,000 2,942E-07 2,711E-04 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 3,000 3,029E-07 1,861E-04 ! regulation of MAP kinase activity GO:0043405 67 66 6,000 3,897E-07 1,796E-04 ! negative regulation of ligase activity GO:0051352 43 42 5,000 4,652E-07 1,715E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 5,000 4,652E-07 1,429E-04 ! regulation of cell migration GO:0030334 71 71 6,000 6,474E-07 1,705E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 5,000 8,126E-07 1,872E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 5,000 1,053E-06 2,156E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 5,000 1,193E-06 2,199E-04 ! regulation of ligase activity GO:0051340 50 49 5,000 1,193E-06 1,999E-04 ! regulation of locomotion GO:0040012 79 79 6,000 1,35E-06 2,074E-04 ! regulation of endothelial cell migration GO:0010594 13 13 3,000 1,682E-06 2,385E-04 ! negative regulation of cell motion GO:0051271 31 31 4,000 2,435E-06 3,205E-04 ! wound healing, spreading of epidermal cells GO:0035313 5 5 2,000 3,576E-06 4,393E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 2,000 3,576E-06 4,119E-04 ! regulation of angiogenesis GO:0045765 35 34 4,000 3,922E-06 4,252E-04 ! proteasomal protein catabolic process GO:0010498 62 61 5,000 4,435E-06 4,541E-04 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cell migration GO:0030335 36 36 4,000 5,256E-06 5,099E-04 ! myelination GO:0042552 17 17 3,000 5,481E-06 5,05E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 3,000 7,009E-06 6,151E-04 ! ensheathment of neurons GO:0007272 18 18 3,000 7,009E-06 5,871E-04 GO:0008366|axon ensheathment, ! regulation of bone resorption GO:0045124 6 6 2,000 7,115E-06 5,701E-04 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 7,115E-06 5,464E-04 ! intestinal absorption GO:0050892 6 6 2,000 7,115E-06 5,245E-04 ! regulation of endothelial cell proliferation GO:0001936 19 19 3,000 8,83E-06 6,259E-04 ! wound healing GO:0042060 74 70 5,000 9,968E-06 6,804E-04 ! regulation of action potential in neuron GO:0019228 21 21 3,000 1,349E-05 8,879E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 4,000 1,449E-05 9,212E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 4,000 1,622E-05 9,963E-04 ! positive regulation of ligase activity GO:0051351 47 46 4,000 1,81E-05 1,076E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 2,000 1,972E-05 1,136E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 2,000 1,972E-05 1,101E-03 ! regulation of action potential GO:0001508 24 24 3,000 2,357E-05 1,278E-03 ! glucose homeostasis GO:0042593 24 24 3,000 2,357E-05 1,241E-03 GO:0033500|carbohydrate homeostasis, ! ossification GO:0001503 50 49 4,000 2,477E-05 1,268E-03 GO:0060348|bone development, ! regulation of intracellular protein transport GO:0033157 25 25 3,000 2,791E-05 1,39E-03 ! negative regulation of cell cycle process GO:0010948 9 9 2,000 2,943E-05 1,427E-03 ! regulation of leukocyte migration GO:0002685 9 9 2,000 2,943E-05 1,391E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 3,273E-05 1,508E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 5,000 3,273E-05 1,471E-03 ! negative regulation of cell migration GO:0030336 26 26 3,000 3,281E-05 1,44E-03 ! response to hypoxia GO:0001666 53 53 4,000 3,646E-05 1,563E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 3,731E-05 1,563E-03 GO:0033674|positive regulation of kinase activity, ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 3,831E-05 1,569E-03 ! response to oxygen levels GO:0070482 55 54 4,000 3,997E-05 1,601E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 4,445E-05 1,743E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 5,721E-05 2,197E-03 GO:0032388|positive regulation of intracellular transport, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 2,000 5,721E-05 2,152E-03 ! cellular response to starvation GO:0009267 11 11 2,000 5,721E-05 2,109E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 5,721E-05 2,067E-03 ! digestive system process GO:0022600 11 11 2,000 5,721E-05 2,028E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 6,722E-05 2,338E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 2,000 7,589E-05 2,59E-03 ! positive regulation of DNA replication GO:0045740 14 13 2,000 9,815E-05 3,289E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 9,815E-05 3,23E-03 ! coenzyme catabolic process GO:0009109 13 13 2,000 9,815E-05 3,174E-03 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! positive regulation of locomotion GO:0040017 13 13 2,000 9,815E-05 3,119E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! regulation of cell-substrate adhesion GO:0010810 14 13 2,000 9,815E-05 3,066E-03 GO:0001952|regulation of cell-matrix adhesion, ! acetyl-CoA metabolic process GO:0006084 14 14 2,000 1,243E-04 3,818E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,243E-04 3,755E-03 ! regulation of behavior GO:0050795 14 14 2,000 1,243E-04 3,694E-03 ! collagen fibril organization GO:0030199 14 14 2,000 1,243E-04 3,636E-03 ! regulation of blood coagulation GO:0030193 15 14 2,000 1,243E-04 3,579E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 1,546E-04 4,382E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 1,546E-04 4,316E-03 ! response to starvation GO:0042594 15 15 2,000 1,546E-04 4,252E-03 ! vacuole organization GO:0007033 16 16 2,000 1,893E-04 5,129E-03 ! cellular response to nutrient levels GO:0031669 16 16 2,000 1,893E-04 5,055E-03 ! cofactor catabolic process GO:0051187 16 16 2,000 1,893E-04 4,983E-03 ! regulation of coagulation GO:0050818 17 16 2,000 1,893E-04 4,913E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 2,286E-04 5,852E-03 ! pigmentation GO:0043473 17 17 2,000 2,286E-04 5,772E-03 ! response to calcium ion GO:0051592 18 18 2,000 2,73E-04 6,798E-03 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 2,73E-04 6,708E-03 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 2,954E-04 7,163E-03 ! blood vessel morphogenesis GO:0048514 84 83 4,000 3,132E-04 7,497E-03 ! regulation of membrane potential GO:0042391 46 46 3,000 3,218E-04 7,603E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 3,225E-04 7,523E-03 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 3,225E-04 7,429E-03 ! peripheral nervous system development GO:0007422 19 19 2,000 3,225E-04 7,337E-03 ! eye morphogenesis GO:0048592 19 19 2,000 3,225E-04 7,248E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 3,775E-04 8,381E-03 ! heart development GO:0007507 90 87 4,000 3,9E-04 8,557E-03 ! gland development GO:0048732 51 49 3,000 4,111E-04 8,914E-03 ! mitotic sister chromatid segregation GO:0000070 21 21 2,000 4,381E-04 9,389E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 4,381E-04 9,281E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 4,381E-04 9,176E-03 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 5,047E-04 0,01045132 ! sister chromatid segregation GO:0000819 22 22 2,000 5,047E-04 0,01033519 ! aerobic respiration GO:0009060 22 22 2,000 5,047E-04 0,01022162 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 5,105E-04 0,01022626 ! prostate gland development GO:0030850 5 5 1,000 5,105E-04 0,0101163 ! mRNA stabilization GO:0048255 5 5 1,000 5,105E-04 0,01000868 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 5,105E-04 9,903E-03 ! adrenal gland development GO:0030325 5 5 1,000 5,105E-04 9,8E-03 ! astrocyte differentiation GO:0048708 5 5 1,000 5,105E-04 9,699E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 5,105E-04 9,6E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 5,105E-04 9,503E-03 ! Schwann cell differentiation GO:0014037 5 5 1,000 5,105E-04 9,408E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 5,105E-04 9,315E-03 ! regulation of gliogenesis GO:0014013 5 5 1,000 5,105E-04 9,224E-03 GO:0045685|regulation of glial cell differentiation, ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 5,105E-04 9,134E-03 ! regulation of interleukin-12 production GO:0032655 5 5 1,000 5,105E-04 9,046E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 5,105E-04 8,96E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 1,000 5,105E-04 8,876E-03 GO:0002688|regulation of leukocyte chemotaxis, ! neuromuscular process controlling posture GO:0050884 5 5 1,000 5,105E-04 8,793E-03 ! regulation of fibrinolysis GO:0051917 5 5 1,000 5,105E-04 8,711E-03 ! negative regulation of organic acid transport GO:0032891 5 5 1,000 5,105E-04 8,631E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 1,000 5,105E-04 8,553E-03 ! regulation of protein transport GO:0051223 53 53 3,000 5,562E-04 9,235E-03 GO:0070201|regulation of establishment of protein localization, ! blood vessel development GO:0001568 95 94 4,000 5,577E-04 9,177E-03 ! negative regulation of multicellular organismal process GO:0051241 55 54 3,000 5,975E-04 9,745E-03 ! vasculature development GO:0001944 97 96 4,000 6,143E-04 9,931E-03 ! regulation of cell adhesion GO:0030155 56 55 3,000 6,409E-04 0,01027186 ! extracellular structure organization GO:0043062 56 56 3,000 6,866E-04 0,01090828 ! regulation of protein localization GO:0032880 58 57 3,000 7,345E-04 0,01156939 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 7,423E-04 0,0115937 ! negative regulation of immune system process GO:0002683 25 25 2,000 7,423E-04 0,01149627 ! virus-host interaction GO:0019048 6 6 1,000 7,622E-04 0,01170556 ! cartilage condensation GO:0001502 7 6 1,000 7,622E-04 0,01160882 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 7,622E-04 0,01151367 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 1,000 7,622E-04 0,01142006 GO:0048844|artery morphogenesis, ! estrogen metabolic process GO:0008210 6 6 1,000 7,622E-04 0,01132797 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 7,622E-04 0,01123734 ! ER overload response GO:0006983 6 6 1,000 7,622E-04 0,01114816 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 7,622E-04 0,01106038 GO:0070667|negative regulation of mast cell proliferation, ! negative regulation of endothelial cell migration GO:0010596 6 6 1,000 7,622E-04 0,01097397 ! lipid digestion GO:0044241 6 6 1,000 7,622E-04 0,0108889 ! phagocytosis, engulfment GO:0006911 6 6 1,000 7,622E-04 0,01080514 ! regulation of vascular permeability GO:0043114 6 6 1,000 7,622E-04 0,01072265 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 7,622E-04 0,01064142 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,622E-04 0,01056141 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 7,622E-04 0,0104826 ! ribosome assembly GO:0042255 6 6 1,000 7,622E-04 0,01040495 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 7,622E-04 0,01032844 ! regulation of lipid transport GO:0032368 6 6 1,000 7,622E-04 0,01025305 ! regulation of RNA splicing GO:0043484 6 6 1,000 7,622E-04 0,01017875 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 7,622E-04 0,01010552 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 7,622E-04 0,01003334 ! localization within membrane GO:0051668 6 6 1,000 7,622E-04 9,962E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 8,348E-04 0,0108353 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 8,373E-04 0,01079074 ! learning or memory GO:0007611 28 27 2,000 9,344E-04 0,01195912 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,062E-03 0,01349933 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 1,062E-03 0,01340687 ! visual behavior GO:0007632 7 7 1,000 1,062E-03 0,01331567 GO:0008542|visual learning, ! regulation of defense response to virus GO:0050688 7 7 1,000 1,062E-03 0,0132257 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,062E-03 0,01313693 ! response to hexose stimulus GO:0009746 7 7 1,000 1,062E-03 0,01304935 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,062E-03 0,01296293 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,062E-03 0,01287765 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! autonomic nervous system development GO:0048483 7 7 1,000 1,062E-03 0,01279348 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 1,062E-03 0,01271041 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 1,062E-03 0,01262841 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,062E-03 0,01254746 ! negative regulation of cellular component organization GO:0051129 65 63 3,000 1,073E-03 0,01259203 ! regulation of response to external stimulus GO:0032101 65 64 3,000 1,138E-03 0,01327554 ! angiogenesis GO:0001525 65 64 3,000 1,138E-03 0,01319204 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,155E-03 0,01330903 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,155E-03 0,01322637 ! positive regulation of protein transport GO:0051222 29 29 2,000 1,155E-03 0,01314472 ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 1,277E-03 0,0144417 ! digestion GO:0007586 31 31 2,000 1,407E-03 0,01581059 ! regulation of DNA replication GO:0006275 32 31 2,000 1,407E-03 0,01571476 ! extracellular matrix organization GO:0030198 31 31 2,000 1,407E-03 0,0156201 ! positive regulation of translation GO:0045727 8 8 1,000 1,41E-03 0,01555543 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,41E-03 0,01546284 ! lipid localization GO:0010876 8 8 1,000 1,41E-03 0,01537134 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 1,41E-03 0,01528092 ! adult walking behavior GO:0007628 8 8 1,000 1,41E-03 0,01519156 ! sex determination GO:0007530 8 8 1,000 1,41E-03 0,01510324 ! embryonic digit morphogenesis GO:0042733 8 8 1,000 1,41E-03 0,01501594 ! gastrulation with mouth forming second GO:0001702 8 8 1,000 1,41E-03 0,01492964 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,41E-03 0,01484433 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,41E-03 0,01475998 ! regulation of RNA stability GO:0043487 8 8 1,000 1,41E-03 0,01467659 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 1,41E-03 0,01459414 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,41E-03 0,01451261 ! regulation of organic acid transport GO:0032890 8 8 1,000 1,41E-03 0,01443198 ! regulation of multi-organism process GO:0043900 8 8 1,000 1,41E-03 0,01435225 ! response to radiation GO:0009314 70 68 3,000 1,428E-03 0,0144604 ! sensory perception of sound GO:0007605 71 69 3,000 1,508E-03 0,01518529 GO:0050954|sensory perception of mechanical stimulus, ! positive regulation of transport GO:0051050 71 70 3,000 1,591E-03 0,01593299 ! ribosome biogenesis GO:0042254 71 71 3,000 1,677E-03 0,01670376 ! negative regulation of signal transduction GO:0009968 71 71 3,000 1,677E-03 0,01661396 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,804E-03 0,01777796 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,804E-03 0,0176834 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,804E-03 0,01758983 ! cerebral cortex development GO:0021987 9 9 1,000 1,804E-03 0,01749726 ! pigmentation during development GO:0048066 9 9 1,000 1,804E-03 0,01740565 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,804E-03 0,01731499 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,804E-03 0,01722528 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,804E-03 0,01713649 ! regulation of bone remodeling GO:0046850 34 34 2,000 1,845E-03 0,01743289 ! response to metal ion GO:0010038 34 34 2,000 1,845E-03 0,01734395 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 1,845E-03 0,01725591 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 2,007E-03 0,01868278 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 2,007E-03 0,01858889 ! regulation of tissue remodeling GO:0034103 35 35 2,000 2,007E-03 0,01849595 ! negative regulation of cell communication GO:0010648 76 76 3,000 2,156E-03 0,01976723 ! response to inorganic substance GO:0010035 36 36 2,000 2,178E-03 0,019876 ! regulation of mitosis GO:0007088 37 36 2,000 2,178E-03 0,01977809 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 2,178E-03 0,01968113 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 2,000 2,178E-03 0,01958513 ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 2,178E-03 0,01949005 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 2,244E-03 0,01998227 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,244E-03 0,0198862 ! glial cell development GO:0021782 10 10 1,000 2,244E-03 0,01979105 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 2,244E-03 0,01969681 ! response to carbohydrate stimulus GO:0009743 10 10 1,000 2,244E-03 0,01960346 ! plasma membrane organization GO:0007009 10 10 1,000 2,244E-03 0,01951099 ! cell-substrate junction assembly GO:0007044 11 10 1,000 2,244E-03 0,01941939 ! neuromuscular junction development GO:0007528 10 10 1,000 2,244E-03 0,01932864 ! sphingolipid catabolic process GO:0030149 10 10 1,000 2,244E-03 0,01923874 GO:0046466|membrane lipid catabolic process, ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,244E-03 0,01914967 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,244E-03 0,01906142 ! negative regulation of coagulation GO:0050819 11 10 1,000 2,244E-03 0,01897399 ! lung development GO:0030324 38 37 2,000 2,359E-03 0,01984927 ! eye development GO:0001654 37 37 2,000 2,359E-03 0,01975905 ! chromosome segregation GO:0007059 38 38 2,000 2,548E-03 0,02124703 ! urogenital system development GO:0001655 38 38 2,000 2,548E-03 0,02115132 ! RNA elongation GO:0006354 38 38 2,000 2,548E-03 0,02105647 ! regulation of homeostatic process GO:0032844 38 38 2,000 2,548E-03 0,02096247 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 2,73E-03 0,02236481 ! skin development GO:0043588 11 11 1,000 2,73E-03 0,02226585 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 2,73E-03 0,02216776 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! spinal cord development GO:0021510 11 11 1,000 2,73E-03 0,02207054 ! interaction with host GO:0051701 11 11 1,000 2,73E-03 0,02197416 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,73E-03 0,02187862 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 2,73E-03 0,02178391 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,73E-03 0,02169001 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,73E-03 0,02159692 ! activation of MAPK activity GO:0000187 39 39 2,000 2,746E-03 0,02162835 ! respiratory tube development GO:0030323 40 39 2,000 2,746E-03 0,02153632 ! respiratory system development GO:0060541 40 39 2,000 2,746E-03 0,02144506 ! protein oligomerization GO:0051259 39 39 2,000 2,746E-03 0,02135458 ! regulation of cellular localization GO:0060341 86 85 3,000 3,243E-03 0,02511529 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 3,261E-03 0,02514864 ! heterophilic cell adhesion GO:0007157 12 12 1,000 3,261E-03 0,02504386 ! collagen metabolic process GO:0032963 12 12 1,000 3,261E-03 0,02493994 ! positive regulation of endocytosis GO:0045807 12 12 1,000 3,261E-03 0,02483688 ! osteoblast differentiation GO:0001649 12 12 1,000 3,261E-03 0,02473467 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 3,261E-03 0,0246333 ! pallium development GO:0021543 13 12 1,000 3,261E-03 0,02453276 ! regulation of chromosome organization GO:0033044 12 12 1,000 3,261E-03 0,02443303 ! regulation of response to biotic stimulus GO:0002831 12 12 1,000 3,261E-03 0,02433411 ! neurotransmitter secretion GO:0007269 14 12 1,000 3,261E-03 0,02423599 ! negative regulation of translation GO:0017148 12 12 1,000 3,261E-03 0,02413866 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 3,836E-03 0,02828184 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 3,836E-03 0,02816916 ! negative regulation of protein modification process GO:0031400 13 13 1,000 3,836E-03 0,02805738 ! vasculogenesis GO:0001570 13 13 1,000 3,836E-03 0,02794648 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 3,836E-03 0,02783645 ! actin filament bundle formation GO:0051017 13 13 1,000 3,836E-03 0,02772729 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,836E-03 0,02761898 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 3,836E-03 0,02751151 ! glycosphingolipid metabolic process GO:0006687 13 13 1,000 3,836E-03 0,02740488 GO:0006664|glycolipid metabolic process, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,836E-03 0,02729907 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,836E-03 0,02719407 ! negative regulation of cytokine production GO:0001818 13 13 1,000 3,836E-03 0,02708988 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 3,836E-03 0,02698648 ! protein tetramerization GO:0051262 13 13 1,000 3,836E-03 0,02688387 ! negative regulation of organelle organization GO:0010639 45 44 2,000 3,88E-03 0,02708307 ! negative regulation of cell cycle GO:0045786 92 91 3,000 4,147E-03 0,02883976 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 3,000 4,312E-03 0,02987822 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 2,000 4,402E-03 0,03038253 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 4,402E-03 0,03026916 ! macromolecular complex disassembly GO:0032984 15 14 1,000 4,455E-03 0,03052302 ! lysosome organization GO:0007040 14 14 1,000 4,455E-03 0,03040997 ! peptide cross-linking GO:0018149 14 14 1,000 4,455E-03 0,03029776 ! neuromuscular process controlling balance GO:0050885 14 14 1,000 4,455E-03 0,03018637 ! regulation of response to stress GO:0080134 97 94 3,000 4,657E-03 0,03143696 ! regulation of cell cycle process GO:0010564 50 48 2,000 4,964E-03 0,03339192 ! protein amino acid O-linked glycosylation GO:0006493 15 15 1,000 5,117E-03 0,0342911 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 5,117E-03 0,03416686 ! negative regulation of cell activation GO:0050866 15 15 1,000 5,117E-03 0,03404351 ! protein homooligomerization GO:0051260 15 15 1,000 5,117E-03 0,03392105 ! endocytosis GO:0006897 99 98 3,000 5,4E-03 0,0356724 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 5,4E-03 0,035545 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 5,569E-03 0,03652425 ! negative regulation of transport GO:0051051 51 50 2,000 5,569E-03 0,03639473 ! transcription initiation GO:0006352 50 50 2,000 5,569E-03 0,03626613 ! response to hormone stimulus GO:0009725 102 100 3,000 5,8E-03 0,03764012 ! learning GO:0007612 16 16 1,000 5,821E-03 0,03763991 ! positive regulation of mitosis GO:0045840 16 16 1,000 5,821E-03 0,03750831 GO:0051785|positive regulation of nuclear division, ! positive regulation of catabolic process GO:0009896 16 16 1,000 5,821E-03 0,03737762 ! rRNA metabolic process GO:0016072 51 51 2,000 5,887E-03 0,0376719 GO:0006364|rRNA processing, ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 5,887E-03 0,03754155 GO:0051325|interphase, ! cholesterol metabolic process GO:0008203 52 52 2,000 6,216E-03 0,03950148 ! response to light stimulus GO:0009416 53 52 2,000 6,216E-03 0,03936573 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 6,566E-03 0,04144352 ! regulation of transmembrane transport GO:0034762 17 17 1,000 6,566E-03 0,04130208 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 6,566E-03 0,0411616 ! leukocyte adhesion GO:0007159 17 17 1,000 6,566E-03 0,04102207 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 6,566E-03 0,04088348 ! cell junction assembly GO:0034329 18 17 1,000 6,566E-03 0,04074582 ! tissue remodeling GO:0048771 17 17 1,000 6,566E-03 0,04060909 ! negative regulation of cell development GO:0010721 18 17 1,000 6,566E-03 0,04047328 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 6,566E-03 0,04033836 ! adult locomotory behavior GO:0008344 17 17 1,000 6,566E-03 0,04020435 ! liver development GO:0001889 17 17 1,000 6,566E-03 0,04007122 ! hormone metabolic process GO:0042445 55 54 2,000 6,906E-03 0,04200374 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 7,353E-03 0,04457669 ! meiosis I GO:0007127 18 18 1,000 7,353E-03 0,04443054 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 7,353E-03 0,04428534 ! cholesterol homeostasis GO:0042632 18 18 1,000 7,353E-03 0,04414109 GO:0055092|sterol homeostasis, ! ceramide metabolic process GO:0006672 18 18 1,000 7,353E-03 0,04399778 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 1,000 7,353E-03 0,04385539 ! negative regulation of MAP kinase activity GO:0043407 18 18 1,000 7,353E-03 0,04371392 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 7,353E-03 0,04357336 ! reproductive developmental process GO:0003006 56 56 2,000 7,64E-03 0,04512732 ! glial cell differentiation GO:0010001 19 19 1,000 8,18E-03 0,04816506 ! metanephros development GO:0001656 19 19 1,000 8,18E-03 0,04801167 ! hormone biosynthetic process GO:0042446 19 19 1,000 8,18E-03 0,04785925 ! regulation of cell shape GO:0008360 21 19 1,000 8,18E-03 0,0477078 ! placenta development GO:0001890 19 19 1,000 8,18E-03 0,0475573 ! response to heat GO:0009408 19 19 1,000 8,18E-03 0,04740775 ! sterol metabolic process GO:0016125 59 59 2,000 8,824E-03 0,05098076 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 9,047E-03 0,05210451 ! phagocytosis GO:0006909 21 20 1,000 9,047E-03 0,0519422 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 2,000 9,242E-03 0,05289518 ! cellular respiration GO:0045333 62 61 2,000 9,67E-03 0,05517858 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 9,953E-03 0,05661589 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 1,000 9,953E-03 0,05644169 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 1,000 9,953E-03 0,05626856 ! cholesterol transport GO:0030301 21 21 1,000 9,953E-03 0,05609648 GO:0015918|sterol transport, ! negative regulation of protein transport GO:0051224 21 21 1,000 9,953E-03 0,05592546 ! cell junction organization GO:0034330 23 22 1,000 0,01089793 0,06104829 ! spindle organization GO:0007051 22 22 1,000 0,01089793 0,0608633 ! cytokinesis GO:0000910 23 22 1,000 0,01089793 0,06067942 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,01150141 0,0638467 ! regulation of hormone levels GO:0010817 66 65 2,000 0,01150141 0,06365497 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,01188083 0,06555802 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01188083 0,06536232 ! endocrine system development GO:0035270 23 23 1,000 0,01188083 0,06516779 ! positive regulation of growth GO:0045927 23 23 1,000 0,01188083 0,06497442 ! lipid homeostasis GO:0055088 23 23 1,000 0,01188083 0,06478219 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01188083 0,06459109 ! polysaccharide metabolic process GO:0005976 69 66 2,000 0,01198828 0,06498351 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,01198828 0,06479294 ! gliogenesis GO:0042063 24 24 1,000 0,01290122 0,06952325 ! glucan metabolic process GO:0044042 25 24 1,000 0,01290122 0,06932056 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of translation GO:0006417 69 69 2,000 0,01351955 0,07243178 ! response to nutrient levels GO:0031667 69 69 2,000 0,01351955 0,07222183 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01351955 0,0720131 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 0,01351955 0,07180557 ! cellular component disassembly GO:0022411 26 25 1,000 0,01395852 0,073924 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01395852 0,07371219 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,01395852 0,07350158 ! gastrulation GO:0007369 25 25 1,000 0,01395852 0,07329217 ! heart morphogenesis GO:0003007 25 25 1,000 0,01395852 0,07308396 ! regulation of endocytosis GO:0030100 25 25 1,000 0,01395852 0,07287692 ! positive regulation of cytokine production GO:0001819 25 25 1,000 0,01395852 0,07267105 ! muscle tissue development GO:0060537 72 70 2,000 0,01405368 0,07296036 ! regulation of cell activation GO:0050865 71 71 2,000 0,01459972 0,07558226 ! glycolysis GO:0006096 26 26 1,000 0,01505216 0,07770625 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,01505216 0,07748919 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01505216 0,07727335 ! synapse organization GO:0050808 26 26 1,000 0,01505216 0,0770587 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,01515771 0,0773841 ! sensory organ development GO:0007423 72 72 2,000 0,01515771 0,07717034 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,01515771 0,07695774 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,01618158 0,08193036 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01618158 0,0817059 ! coenzyme metabolic process GO:0006732 75 74 2,000 0,01630966 0,08212762 ! neuromuscular process GO:0050905 28 28 1,000 0,01734622 0,08710924 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01734622 0,08687253 ! cartilage development GO:0051216 29 28 1,000 0,01734622 0,08663711 ! viral reproductive process GO:0022415 29 29 1,000 0,01854554 0,09237686 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,01854554 0,09212786 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01854554 0,09188021 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01854554 0,09163388 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01854554 0,09138887 ! adult behavior GO:0030534 30 29 1,000 0,01854554 0,09114516 ! response to UV GO:0009411 29 29 1,000 0,01854554 0,09090276 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01875817 0,09170107 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01977899 0,09643567 GO:0010863|positive regulation of phospholipase C activity, ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,01977899 0,09618122 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01977899 0,09592811 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01977899 0,09567633 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01977899 0,09542587 ! MAPKKK cascade GO:0000165 82 81 2,000 0,02072169 0,09971297 ! tube development GO:0035295 83 81 2,000 0,02072169 0,0994533 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02104603 0,10074763 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,02104603 0,10048662 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02104603 0,10022697 ! sphingolipid metabolic process GO:0006665 31 31 1,000 0,02104603 0,09996865 ! camera-type eye development GO:0043010 31 31 1,000 0,02104603 0,09971166 ! ribonucleoprotein complex assembly GO:0022618 32 31 1,000 0,02104603 0,09945599 ! ncRNA processing GO:0034470 83 83 2,000 0,02209144 0,10412922 ! muscle fiber development GO:0048747 32 32 1,000 0,02234613 0,10506102 ! glucose catabolic process GO:0006007 32 32 1,000 0,02234613 0,10479369 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02234613 0,10452771 ! glycosaminoglycan metabolic process GO:0030203 34 32 1,000 0,02234613 0,10426309 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02234613 0,1039998 ! cell maturation GO:0048469 32 32 1,000 0,02234613 0,10373783 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02234613 0,10347718 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,02234613 0,10321784 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02234613 0,1029598 ! kidney development GO:0001822 32 32 1,000 0,02234613 0,10270304 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02234613 0,10244756 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,02350985 0,10751527 ! membrane lipid metabolic process GO:0006643 33 33 1,000 0,02367876 0,1080197 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02367876 0,10775298 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,0250434 0,11368225 ! viral reproduction GO:0016032 34 34 1,000 0,0250434 0,11340293 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02643954 0,11943155 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02643954 0,11913954 ! regulation of immune effector process GO:0002697 35 35 1,000 0,02643954 0,11884895 ! regulation of Ras protein signal transduction GO:0046578 90 90 2,000 0,02726878 0,12227827 ! brain development GO:0007420 91 90 2,000 0,02726878 0,12198148 ! aminoglycan metabolic process GO:0006022 38 36 1,000 0,02786666 0,12435413 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,02786666 0,12405375 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02786666 0,12375483 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02786666 0,12345734 ! coagulation GO:0050817 39 36 1,000 0,02786666 0,12316128 GO:0007596|blood coagulation, ! visual perception GO:0007601 93 92 2,000 0,02885742 0,12723498 GO:0050953|sensory perception of light stimulus, ! positive regulation of immune system process GO:0002684 92 92 2,000 0,02885742 0,12693132 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02932426 0,12867765 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 1,000 0,02932426 0,128372 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,02932426 0,1280678 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,02932426 0,12776504 ! adaptive immune response GO:0002250 37 37 1,000 0,02932426 0,12746371 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! epidermis development GO:0008544 94 94 2,000 0,03049453 0,13223865 ! cofactor metabolic process GO:0051186 95 94 2,000 0,03049453 0,13192823 ! neurotransmitter transport GO:0006836 40 38 1,000 0,03081184 0,13298882 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,03081184 0,13267809 ! exocytosis GO:0006887 40 38 1,000 0,03081184 0,13236882 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,03081184 0,13206099 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,03081184 0,13175458 ! hexose catabolic process GO:0019320 38 38 1,000 0,03081184 0,13144959 ! meiotic cell cycle GO:0051321 38 38 1,000 0,03081184 0,13114602 ! axon guidance GO:0007411 39 38 1,000 0,03081184 0,13084384 ! regulation of cell growth GO:0001558 97 96 2,000 0,03218001 0,13633969 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,03232891 0,13665638 ! hemostasis GO:0007599 42 39 1,000 0,03232891 0,13634366 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,03232891 0,13603238 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,03232891 0,13572251 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,03232891 0,13541405 ! developmental maturation GO:0021700 39 39 1,000 0,03232891 0,13510699 ! limb development GO:0060173 39 39 1,000 0,03232891 0,13480131 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,03387498 0,14092908 ! DNA catabolic process GO:0006308 41 40 1,000 0,03387498 0,14061167 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,03387498 0,14029569 ! organelle localization GO:0051640 41 40 1,000 0,03387498 0,13998112 ! ectoderm development GO:0007398 99 99 2,000 0,03479858 0,14347601 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03544956 0,14583378 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 0,03544956 0,14550898 ! regulation of caspase activity GO:0043281 41 41 1,000 0,03544956 0,14518563 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 0,03544956 0,14486371 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,03544956 0,14454322 ! muscle organ development GO:0007517 102 100 2,000 0,03569543 0,14522447 ! rRNA transcription GO:0009303 5 5 0,000 0,03582314 0,14542301 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03582314 0,1451034 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03582314 0,14478519 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03582314 0,14446838 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03582314 0,14415294 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03582314 0,14383888 ! reproductive cellular process GO:0048610 5 5 0,000 0,03582314 0,14352619 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03582314 0,14321485 ! metencephalon development GO:0022037 5 5 0,000 0,03582314 0,14290487 ! water transport GO:0006833 5 5 0,000 0,03582314 0,14259622 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03582314 0,1422889 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03582314 0,1419829 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03582314 0,14167821 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03582314 0,14137483 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03582314 0,14107275 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03582314 0,14077196 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03582314 0,14047244 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03582314 0,1401742 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03582314 0,13987722 ! filopodium assembly GO:0046847 7 5 0,000 0,03582314 0,1395815 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03582314 0,13928702 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03582314 0,13899378 ! GTP metabolic process GO:0046039 5 5 0,000 0,03582314 0,13870178 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03582314 0,138411 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03582314 0,13812144 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03582314 0,13783309 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03582314 0,13754593 ! social behavior GO:0035176 5 5 0,000 0,03582314 0,13725997 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03582314 0,1369752 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03582314 0,13669161 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03582314 0,13640919 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03582314 0,13612793 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03582314 0,13584784 ! response to lipid GO:0033993 5 5 0,000 0,03582314 0,13556889 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03582314 0,13529108 ! hippocampus development GO:0021766 6 5 0,000 0,03582314 0,13501441 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03582314 0,13473887 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03582314 0,13446446 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03582314 0,13419115 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03582314 0,13391896 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03582314 0,13364787 ! heart looping GO:0001947 5 5 0,000 0,03582314 0,13337787 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03582314 0,13310897 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03582314 0,13284114 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03582314 0,13257439 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03582314 0,13230871 ! pH reduction GO:0045851 5 5 0,000 0,03582314 0,1320441 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03582314 0,13178053 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03582314 0,13151802 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03582314 0,13125656 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03582314 0,13099613 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03582314 0,13073673 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03582314 0,13047836 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03582314 0,130221 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03582314 0,12996466 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03582314 0,12970933 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03582314 0,129455 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03582314 0,12920166 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03582314 0,12894931 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03582314 0,12869795 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03582314 0,12844756 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03582314 0,12819815 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03582314 0,12794971 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03582314 0,12770222 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03582314 0,12745569 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03582314 0,12721011 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03582314 0,12696548 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03582314 0,12672178 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03582314 0,12647902 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03582314 0,12623719 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03582314 0,12599627 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03582314 0,12575628 ! response to ATP GO:0033198 5 5 0,000 0,03582314 0,1255172 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03582314 0,12527903 ! regulation of appetite GO:0032098 5 5 0,000 0,03582314 0,12504176 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03582314 0,12480538 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03582314 0,1245699 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03582314 0,12433531 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03582314 0,12410159 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03582314 0,12386876 ! receptor clustering GO:0043113 5 5 0,000 0,03582314 0,12363679 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03582314 0,1234057 ! fear response GO:0042596 5 5 0,000 0,03582314 0,12317546 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03582314 0,12294609 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03582314 0,12271756 ! retinol metabolic process GO:0042572 5 5 0,000 0,03582314 0,12248988 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03582314 0,12226305 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03582314 0,12203706 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03582314 0,1218119 ! parturition GO:0007567 5 5 0,000 0,03582314 0,12158757 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03582314 0,12136406 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03582314 0,12114137 ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03582314 0,1209195 ! response to UV-B GO:0010224 5 5 0,000 0,03582314 0,12069844 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03582314 0,12047819 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03582314 0,12025874 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03582314 0,12004009 ! interaction with symbiont GO:0051702 5 5 0,000 0,03582314 0,11982223 ! cellular extravasation GO:0045123 5 5 0,000 0,03582314 0,11960516 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03582314 0,11938887 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03582314 0,11917337 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03582314 0,11895864 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03582314 0,11874469 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03582314 0,1185315 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03582314 0,11831908 ! response to amine stimulus GO:0014075 5 5 0,000 0,03582314 0,11810742 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03582314 0,11789651 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03582314 0,11768636 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03582314 0,11747695 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03582314 0,11726829 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03582314 0,11706037 ! neuron recognition GO:0008038 5 5 0,000 0,03582314 0,11685318 ! decidualization GO:0046697 5 5 0,000 0,03582314 0,11664673 ! hair follicle maturation GO:0048820 5 5 0,000 0,03582314 0,116441 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03582314 0,116236 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03582314 0,11603172 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03582314 0,11582815 GO:0009155|purine deoxyribonucleotide catabolic process, ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03582314 0,1156253 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03582314 0,11542316 ! postreplication repair GO:0006301 5 5 0,000 0,03582314 0,11522172 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03582314 0,11502099 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03582314 0,11482095 ! histone methylation GO:0016571 5 5 0,000 0,03582314 0,11462161 ! DNA methylation GO:0006306 5 5 0,000 0,03582314 0,11442296 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03582314 0,114225 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03582314 0,11402772 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03582314 0,11383112 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03582314 0,11363519 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03582314 0,11343994 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03582314 0,11324537 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03582314 0,11305145 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03582314 0,1128582 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03582314 0,11266561 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03582314 0,11247368 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03582314 0,11228239 ! sterol catabolic process GO:0016127 5 5 0,000 0,03582314 0,11209176 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03582314 0,11190178 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03582314 0,11171243 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03582314 0,11152373 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03582314 0,11133566 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03582314 0,11114823 ! zymogen activation GO:0031638 5 5 0,000 0,03582314 0,11096142 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03582314 0,11077525 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03582314 0,11058969 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03582314 0,11040476 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,03582314 0,11022045 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03582314 0,11003675 ! nucleosome positioning GO:0016584 5 5 0,000 0,03582314 0,10985366 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03582314 0,10967118 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03582314 0,1094893 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03582314 0,10930803 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03582314 0,10912735 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03582314 0,10894727 ! NADPH regeneration GO:0006740 5 5 0,000 0,03582314 0,10876779 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03582314 0,10858889 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03582314 0,10841059 ! musculoskeletal movement GO:0050881 5 5 0,000 0,03582314 0,10823287 GO:0050879|multicellular organismal movement, ! sarcomere organization GO:0045214 5 5 0,000 0,03582314 0,10805572 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03582314 0,10787916 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03582314 0,10770318 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03582314 0,10752777 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03582314 0,10735292 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03582314 0,10717865 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03582314 0,10700494 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03582314 0,10683179 ! spleen development GO:0048536 5 5 0,000 0,03582314 0,1066592 ! male genitalia development GO:0030539 5 5 0,000 0,03582314 0,10648717 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03582314 0,1063157 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03582314 0,10614477 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03582314 0,10597439 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03582314 0,10580456 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03582314 0,10563528 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03582314 0,10546653 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03582314 0,10529832 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03582314 0,10513065 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03582314 0,10496351 ! ATP catabolic process GO:0006200 5 5 0,000 0,03582314 0,1047969 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03582314 0,10463082 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03582314 0,10446527 ! blastocyst formation GO:0001825 5 5 0,000 0,03582314 0,10430023 ! embryonic gut development GO:0048566 5 5 0,000 0,03582314 0,10413572 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03582314 0,10397173 ! activation of innate immune response GO:0002218 5 5 0,000 0,03582314 0,10380825 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03582314 0,10364529 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03582314 0,10348283 ! muscle adaptation GO:0043500 5 5 0,000 0,03582314 0,10332089 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03582314 0,10315945 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03582314 0,10299851 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03582314 0,10283808 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03582314 0,10267815 ! defense response to fungus GO:0050832 5 5 0,000 0,03582314 0,10251871 ! lysogeny GO:0030069 5 5 0,000 0,03582314 0,10235976 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03582314 0,10220131 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03582314 0,10204335 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03582314 0,10188588 ! response to nicotine GO:0035094 5 5 0,000 0,03582314 0,10172889 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03582314 0,10157238 ! mitochondrion localization GO:0051646 5 5 0,000 0,03582314 0,10141636 ! nucleus localization GO:0051647 5 5 0,000 0,03582314 0,10126081 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03582314 0,10110574 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,03705218 0,10441462 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03705218 0,1042552 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,03705218 0,10409628 ! forebrain development GO:0030900 43 42 1,000 0,03705218 0,10393784 ! reproductive structure development GO:0048608 43 43 1,000 0,03868236 0,10834587 ! alcohol catabolic process GO:0046164 43 43 1,000 0,03868236 0,10818146 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03868236 0,10801755 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,04202355 0,11717004 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,04202355 0,11699305 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,04202355 0,11681659 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04283534 0,11889386 ! axon extension GO:0048675 7 6 0,000 0,04283534 0,11871507 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04283534 0,11853682 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,04283534 0,11835911 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,04283534 0,11818192 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04283534 0,11800527 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04283534 0,11782914 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04283534 0,11765354 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04283534 0,11747846 ! regulation of S phase GO:0033261 6 6 0,000 0,04283534 0,1173039 ! myotube differentiation GO:0014902 6 6 0,000 0,04283534 0,11712986 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04283534 0,11695633 ! bone remodeling GO:0046849 6 6 0,000 0,04283534 0,11678332 ! N-glycan processing GO:0006491 6 6 0,000 0,04283534 0,11661082 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04283534 0,11643883 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04283534 0,11626734 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04283534 0,11609636 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04283534 0,11592588 ! RNA methylation GO:0001510 6 6 0,000 0,04283534 0,1157559 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04283534 0,11558642 ! succinate metabolic process GO:0006105 7 6 0,000 0,04283534 0,11541743 ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04283534 0,11524894 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04283534 0,11508094 ! androgen metabolic process GO:0008209 6 6 0,000 0,04283534 0,11491343 ! limbic system development GO:0021761 7 6 0,000 0,04283534 0,1147464 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04283534 0,11457986 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04283534 0,1144138 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04283534 0,11424823 ! pathogenesis GO:0009405 6 6 0,000 0,04283534 0,11408313 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04283534 0,1139185 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04283534 0,11375436 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04283534 0,11359068 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04283534 0,11342748 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04283534 0,11326474 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04283534 0,11310247 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04283534 0,11294066 ! arginine metabolic process GO:0006525 6 6 0,000 0,04283534 0,11277932 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04283534 0,11261844 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04283534 0,11245801 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04283534 0,11229804 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04283534 0,11213853 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04283534 0,11197947 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04283534 0,11182086 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04283534 0,11166269 ! V(D)J recombination GO:0033151 6 6 0,000 0,04283534 0,11150498 ! focal adhesion formation GO:0048041 7 6 0,000 0,04283534 0,11134771 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04283534 0,11119088 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04283534 0,11103449 ! regulation of heart rate GO:0002027 6 6 0,000 0,04283534 0,11087854 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04283534 0,11072303 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04283534 0,11056796 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04283534 0,11041332 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04283534 0,11025911 ! ruffle organization GO:0031529 6 6 0,000 0,04283534 0,11010533 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04283534 0,10995198 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04283534 0,10979906 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04283534 0,10964656 ! L-amino acid transport GO:0015807 6 6 0,000 0,04283534 0,10949449 ! bone mineralization GO:0030282 6 6 0,000 0,04283534 0,10934283 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04283534 0,1091916 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04283534 0,10904078 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04283534 0,10889038 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04283534 0,10874039 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04283534 0,10859082 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04283534 0,10844165 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04283534 0,1082929 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04283534 0,10814455 ! regulation of organ growth GO:0046620 6 6 0,000 0,04283534 0,10799661 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04283534 0,10784908 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04283534 0,10770194 ! response to dsRNA GO:0043331 6 6 0,000 0,04283534 0,10755521 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04283534 0,10740888 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04283534 0,10726294 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04283534 0,1071174 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04283534 0,10697225 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04283534 0,1068275 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04283534 0,10668314 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04283534 0,10653917 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04283534 0,10639558 ! erythrocyte development GO:0048821 6 6 0,000 0,04283534 0,10625239 ! renal water homeostasis GO:0003091 6 6 0,000 0,04283534 0,10610958 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04283534 0,10596715 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04283534 0,1058251 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04283534 0,10568343 ! diencephalon development GO:0021536 6 6 0,000 0,04283534 0,10554214 ! fucose catabolic process GO:0019317 6 6 0,000 0,04283534 0,10540123 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04283534 0,1052607 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04283534 0,10512054 ! regulation of cell division GO:0051302 6 6 0,000 0,04283534 0,10498075 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04283534 0,10484133 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04283534 0,10470229 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04283534 0,10456361 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04283534 0,1044253 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04283534 0,10428735 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04283534 0,10414977 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04283534 0,10401255 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04283534 0,10387569 GO:0046324|regulation of glucose import, ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04283534 0,10373919 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04283534 0,10360305 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04283534 0,10346727 ! thymus development GO:0048538 6 6 0,000 0,04283534 0,10333184 ! lymph node development GO:0048535 6 6 0,000 0,04283534 0,10319676 ! organic cation transport GO:0015695 6 6 0,000 0,04283534 0,10306204 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04283534 0,10292767 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04283534 0,10279365 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04283534 0,10265998 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04283534 0,10252665 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04283534 0,10239368 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04283534 0,10226104 ! alditol metabolic process GO:0019400 6 6 0,000 0,04283534 0,10212875 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04283534 0,1019968 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04283534 0,10186519 ! maternal placenta development GO:0001893 6 6 0,000 0,04283534 0,10173392 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04283534 0,10160299 ! tube morphogenesis GO:0035239 47 46 1,000 0,04373364 0,10360038 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,04373364 0,10346739 ! rhythmic process GO:0048511 47 47 1,000 0,04546945 0,10743615 ! regulation of catabolic process GO:0009894 48 47 1,000 0,04546945 0,10729859 ! calcium ion transport GO:0006816 48 48 1,000 0,04723054 0,11131187 ! actin filament organization GO:0007015 50 48 1,000 0,04723054 0,11116971 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,04723054 0,11102791 ! cell cycle arrest GO:0007050 49 49 1,000 0,04901646 0,11507941 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,04901646 0,114933 ! divalent metal ion transport GO:0070838 49 49 1,000 0,04901646 0,11478696 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,04901646 0,11464129 GO:0060538|skeletal muscle organ development, ! positive regulation of cell activation GO:0050867 49 49 1,000 0,04901646 0,11449599 GO:0002696|positive regulation of leukocyte activation, ! respiratory burst GO:0045730 7 7 0,000 0,04979755 0,11617326 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04979755 0,11602639 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04979755 0,1158799 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04979755 0,11573377 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04979755 0,11558801 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04979755 0,11544261 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04979755 0,11529758 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04979755 0,11515292 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04979755 0,11500862 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04979755 0,11486468 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04979755 0,1147211 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04979755 0,11457787 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04979755 0,11443501 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04979755 0,1142925 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04979755 0,11415034 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04979755 0,11400854 ! axis specification GO:0009798 7 7 0,000 0,04979755 0,11386709 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04979755 0,11372599 ! startle response GO:0001964 7 7 0,000 0,04979755 0,11358524 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04979755 0,11344484 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04979755 0,11330479 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04979755 0,11316508 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04979755 0,11302571 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04979755 0,11288669 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04979755 0,11274801 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04979755 0,11260967 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04979755 0,11247166 ! digestive system development GO:0055123 7 7 0,000 0,04979755 0,112334 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04979755 0,11219667 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04979755 0,11205968 ! protein targeting to ER GO:0045047 8 7 0,000 0,04979755 0,11192302 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04979755 0,1117867 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04979755 0,1116507 ! endoderm development GO:0007492 7 7 0,000 0,04979755 0,11151504 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04979755 0,11137971 GO:0006688|glycosphingolipid biosynthetic process, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04979755 0,1112447 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04979755 0,11111002 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04979755 0,11097567 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04979755 0,11084164 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04979755 0,11070793 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04979755 0,11057455 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04979755 0,11044149 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04979755 0,11030875 ! response to X-ray GO:0010165 7 7 0,000 0,04979755 0,11017632 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04979755 0,11004422 ! UV protection GO:0009650 7 7 0,000 0,04979755 0,10991243 ! DNA integration GO:0015074 7 7 0,000 0,04979755 0,10978095 ! myofibril assembly GO:0030239 7 7 0,000 0,04979755 0,10964979 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04979755 0,10951895 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04979755 0,10938841 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04979755 0,10925819 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04979755 0,10912827 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04979755 0,10899867 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04979755 0,10886937 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04979755 0,10874038 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04979755 0,10861169 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04979755 0,10848331 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04979755 0,10835523 ! axon cargo transport GO:0008088 7 7 0,000 0,04979755 0,10822745 ! eating behavior GO:0042755 7 7 0,000 0,04979755 0,10809997 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04979755 0,1079728 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04979755 0,10784592 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04979755 0,10771934 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04979755 0,10759306 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04979755 0,10746707 ! cranial nerve development GO:0021545 7 7 0,000 0,04979755 0,10734138 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04979755 0,10721598 ! induction of an organ GO:0001759 7 7 0,000 0,04979755 0,10709087 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04979755 0,10696606 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04979755 0,10684153 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04979755 0,1067173 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04979755 0,10659335 ! platelet activation GO:0030168 8 7 0,000 0,04979755 0,1064697 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04979755 0,10634632 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04979755 0,10622324 ! natural killer cell activation GO:0030101 7 7 0,000 0,04979755 0,10610044 ! response to gamma radiation GO:0010332 8 7 0,000 0,04979755 0,10597792 ! NADP metabolic process GO:0006739 7 7 0,000 0,04979755 0,10585568 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04979755 0,10573373 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04979755 0,10561206 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04979755 0,10549066 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04979755 0,10536955 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04979755 0,10524871 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04979755 0,10512815 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04979755 0,10500787 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04979755 0,10488786 ! cell-cell recognition GO:0009988 8 7 0,000 0,04979755 0,10476812 ! hormone catabolic process GO:0042447 7 7 0,000 0,04979755 0,10464866 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04979755 0,10452947 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04979755 0,10441055 ! oxygen transport GO:0015671 7 7 0,000 0,04979755 0,10429191 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04979755 0,10417353 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04979755 0,10405542 ! regulation of axon extension GO:0030516 7 7 0,000 0,04979755 0,10393757 ! cell killing GO:0001906 7 7 0,000 0,04979755 0,10382 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04979755 0,10370269 ! adult feeding behavior GO:0008343 7 7 0,000 0,04979755 0,10358564 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04979755 0,10346886 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04979755 0,10335234 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04979755 0,10323608 ! response to cold GO:0009409 7 7 0,000 0,04979755 0,10312009 ! regulation of defense response GO:0031347 50 50 1,000 0,05082678 0,10513329 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,05082678 0,10501542 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,05082678 0,10489782 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,05451888 0,11239183 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,05451888 0,11226625 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,05639981 0,11600987 ! regulation of T cell activation GO:0050863 53 53 1,000 0,05639981 0,11588054 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05671012 0,11638836 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05671012 0,1162589 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05671012 0,11612972 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05671012 0,11600083 ! superoxide anion generation GO:0042554 8 8 0,000 0,05671012 0,11587223 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05671012 0,11574391 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05671012 0,11561588 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05671012 0,11548812 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05671012 0,11536065 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05671012 0,11523346 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05671012 0,11510655 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05671012 0,11497992 ! zinc ion transport GO:0006829 8 8 0,000 0,05671012 0,11485357 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05671012 0,1147275 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05671012 0,1146017 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05671012 0,11447618 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05671012 0,11435093 ! response to pain GO:0048265 8 8 0,000 0,05671012 0,11422596 ! response to cAMP GO:0051591 8 8 0,000 0,05671012 0,11410126 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05671012 0,11397683 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05671012 0,11385267 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05671012 0,11372878 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05671012 0,11360516 GO:0032107|regulation of response to nutrient levels, ! sensory perception of taste GO:0050909 8 8 0,000 0,05671012 0,11348182 ! organelle fusion GO:0048284 8 8 0,000 0,05671012 0,11335873 ! pancreas development GO:0031016 8 8 0,000 0,05671012 0,11323592 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05671012 0,11311337 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05671012 0,11299108 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05671012 0,11286906 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05671012 0,1127473 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05671012 0,11262581 ! sperm motility GO:0030317 8 8 0,000 0,05671012 0,11250458 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05671012 0,1123836 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05671012 0,11226289 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05671012 0,11214244 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05671012 0,11202224 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05671012 0,1119023 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05671012 0,11178262 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05671012 0,1116632 ! Golgi organization GO:0007030 8 8 0,000 0,05671012 0,11154403 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05671012 0,11142511 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05671012 0,11130644 ! fructose metabolic process GO:0006000 8 8 0,000 0,05671012 0,11118803 ! mannose metabolic process GO:0006013 9 8 0,000 0,05671012 0,11106987 ! NAD metabolic process GO:0019674 8 8 0,000 0,05671012 0,11095197 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05671012 0,11083431 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05671012 0,1107169 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,05671012 0,11059974 ! response to fungus GO:0009620 8 8 0,000 0,05671012 0,11048282 ! stem cell differentiation GO:0048863 8 8 0,000 0,05671012 0,11036616 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05671012 0,11024974 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05671012 0,11013356 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05671012 0,11001763 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05671012 0,10990195 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05671012 0,1097865 ! vasoconstriction GO:0042310 8 8 0,000 0,05671012 0,1096713 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05671012 0,10955634 ! muscle cell development GO:0055001 8 8 0,000 0,05671012 0,10944162 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05671012 0,10932715 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05671012 0,10921291 ! sensory perception of pain GO:0019233 8 8 0,000 0,05671012 0,10909891 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05671012 0,10898514 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05671012 0,10887162 ! chromatin silencing GO:0006342 8 8 0,000 0,05671012 0,10875833 ! tissue regeneration GO:0042246 8 8 0,000 0,05671012 0,10864527 ! salivary gland development GO:0007431 8 8 0,000 0,05671012 0,10853245 ! T cell homeostasis GO:0043029 8 8 0,000 0,05671012 0,10841987 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05671012 0,10830751 ! water homeostasis GO:0030104 8 8 0,000 0,05671012 0,1081954 ! cofactor transport GO:0051181 8 8 0,000 0,05671012 0,10808351 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05671012 0,10797185 ! acid secretion GO:0046717 8 8 0,000 0,05671012 0,10786042 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05671012 0,10774923 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05671012 0,10763826 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05671012 0,10752752 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05671012 0,10741701 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05671012 0,10730673 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05671012 0,10719667 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,05671012 0,10708684 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05671012 0,10697723 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05671012 0,10686784 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05671012 0,10675868 ! developmental induction GO:0031128 8 8 0,000 0,05671012 0,10664975 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05671012 0,10654103 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05671012 0,10643254 ! actin filament polymerization GO:0030041 9 8 0,000 0,05671012 0,10632426 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05671012 0,10621621 ! peptide hormone processing GO:0016486 8 8 0,000 0,05671012 0,10610838 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05671012 0,10600076 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05671012 0,10589337 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,06022933 0,11235086 ! regulation of nervous system development GO:0051960 57 56 1,000 0,0621771 0,11586693 ! lactation GO:0007595 10 9 0,000 0,06357341 0,11834928 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06357341 0,11822985 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06357341 0,11811067 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06357341 0,11799173 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06357341 0,11787302 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06357341 0,11775456 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06357341 0,11763633 ! viral genome replication GO:0019079 9 9 0,000 0,06357341 0,11751834 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06357341 0,11740059 ! copper ion transport GO:0006825 9 9 0,000 0,06357341 0,11728307 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06357341 0,11716579 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06357341 0,11704874 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06357341 0,11693192 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06357341 0,11681534 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06357341 0,11669899 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06357341 0,11658287 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06357341 0,11646698 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06357341 0,11635133 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06357341 0,1162359 ! phospholipid efflux GO:0033700 9 9 0,000 0,06357341 0,1161207 ! response to alkaloid GO:0043279 10 9 0,000 0,06357341 0,11600573 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06357341 0,11589098 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06357341 0,11577647 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06357341 0,11566218 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06357341 0,11554811 ! response to ethanol GO:0045471 9 9 0,000 0,06357341 0,11543427 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06357341 0,11532066 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06357341 0,11520726 ! methionine metabolic process GO:0006555 9 9 0,000 0,06357341 0,11509409 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06357341 0,11498114 ! response to osmotic stress GO:0006970 9 9 0,000 0,06357341 0,11486842 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06357341 0,11475591 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06357341 0,11464363 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06357341 0,11453156 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06357341 0,11441971 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06357341 0,11430808 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06357341 0,11419667 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06357341 0,11408548 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06357341 0,1139745 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,06357341 0,11386374 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06357341 0,11375319 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06357341 0,11364286 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06357341 0,11353274 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06357341 0,11342283 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06357341 0,11331314 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06357341 0,11320366 ! DNA replication initiation GO:0006270 9 9 0,000 0,06357341 0,11309439 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06357341 0,11298533 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06357341 0,11287648 ! regulation of cellular pH GO:0030641 9 9 0,000 0,06357341 0,11276784 ! histone acetylation GO:0016573 9 9 0,000 0,06357341 0,11265941 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06357341 0,11255119 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06357341 0,11244317 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06357341 0,11233537 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06357341 0,11222776 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06357341 0,11212037 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06357341 0,11201318 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06357341 0,11190619 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06357341 0,11179941 ! collagen catabolic process GO:0030574 9 9 0,000 0,06357341 0,11169284 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06357341 0,11158646 ! purine base metabolic process GO:0006144 9 9 0,000 0,06357341 0,11148029 ! gas transport GO:0015669 9 9 0,000 0,06357341 0,11137432 ! cholesterol efflux GO:0033344 9 9 0,000 0,06357341 0,11126855 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06357341 0,11116298 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06357341 0,11105762 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06357341 0,11095245 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06357341 0,11084748 ! defense response to virus GO:0051607 9 9 0,000 0,06357341 0,11074271 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06357341 0,11063814 ! actin filament-based movement GO:0030048 9 9 0,000 0,06357341 0,11053376 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06357341 0,11042958 ! regulation of cell development GO:0060284 60 59 1,000 0,06814759 0,11826367 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07038775 0,12203633 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07038775 0,12192163 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,07038775 0,12180715 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07038775 0,12169288 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07038775 0,12157883 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07038775 0,12146499 ! neuron maturation GO:0042551 10 10 0,000 0,07038775 0,12135137 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07038775 0,12123796 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07038775 0,12112476 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07038775 0,12101177 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07038775 0,12089899 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,07038775 0,12078642 ! hormone secretion GO:0046879 10 10 0,000 0,07038775 0,12067406 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07038775 0,12056191 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07038775 0,12044997 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07038775 0,12033823 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07038775 0,1202267 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07038775 0,12011538 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07038775 0,12000427 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07038775 0,11989336 ! phototransduction GO:0007602 11 10 0,000 0,07038775 0,11978265 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07038775 0,11967215 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,07038775 0,11956186 ! fat cell differentiation GO:0045444 10 10 0,000 0,07038775 0,11945176 ! myoblast differentiation GO:0045445 10 10 0,000 0,07038775 0,11934187 ! centrosome cycle GO:0007098 10 10 0,000 0,07038775 0,11923218 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07038775 0,11912269 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07038775 0,11901341 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07038775 0,11890432 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07038775 0,11879543 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,07038775 0,11868675 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07038775 0,11857826 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07038775 0,11846997 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07038775 0,11836187 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,07038775 0,11825398 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07038775 0,11814628 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07038775 0,11803878 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07038775 0,11793147 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07038775 0,11782435 ! exocrine system development GO:0035272 10 10 0,000 0,07038775 0,11771744 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07038775 0,11761071 ! embryo implantation GO:0007566 11 10 0,000 0,07038775 0,11750418 ! regulation of protein binding GO:0043393 11 10 0,000 0,07038775 0,11739784 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07038775 0,11729169 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07038775 0,11718574 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07038775 0,11707998 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07038775 0,1169744 ! protein export from nucleus GO:0006611 10 10 0,000 0,07038775 0,11686902 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07038775 0,11676383 ! cytolysis GO:0019835 10 10 0,000 0,07038775 0,11665883 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07038775 0,11655401 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07038775 0,11644938 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07038775 0,11634495 ! histone deacetylation GO:0016575 10 10 0,000 0,07038775 0,11624069 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07038775 0,11613663 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07038775 0,11603275 ! gland morphogenesis GO:0022612 10 10 0,000 0,07038775 0,11592906 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07038775 0,11582555 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07038775 0,11572223 GO:0046467|membrane lipid biosynthetic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07038775 0,11561909 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07038775 0,11551613 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07038775 0,11541336 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07038775 0,11531077 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07038775 0,11520836 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07038775 0,11510614 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,07038775 0,11500409 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07038775 0,11490223 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,07038775 0,11480054 ! nerve development GO:0021675 10 10 0,000 0,07038775 0,11469904 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07038775 0,11459772 ! gut development GO:0048565 10 10 0,000 0,07038775 0,11449657 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07038775 0,1143956 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07038775 0,11429481 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07038775 0,1141942 ! protein stabilization GO:0050821 10 10 0,000 0,07038775 0,11409377 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,07222997 0,116977 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,07222997 0,1168743 ! lipid transport GO:0006869 62 62 1,000 0,0743006 0,12011931 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,0743006 0,12001403 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,0743006 0,11990894 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,0743006 0,11980403 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,0743006 0,11969931 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,0743006 0,11959477 ! glucose metabolic process GO:0006006 63 63 1,000 0,07639037 0,12285118 ! protein secretion GO:0009306 11 11 0,000 0,07715348 0,12397024 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07715348 0,12386225 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07715348 0,12375445 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07715348 0,12364684 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07715348 0,12353942 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07715348 0,12343218 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07715348 0,12332512 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07715348 0,12321826 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07715348 0,12311157 ! signal complex assembly GO:0007172 11 11 0,000 0,07715348 0,12300508 ! microtubule-based transport GO:0010970 11 11 0,000 0,07715348 0,12289876 ! endothelial cell migration GO:0043542 11 11 0,000 0,07715348 0,12279263 ! peroxisomal transport GO:0043574 11 11 0,000 0,07715348 0,12268668 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07715348 0,12258092 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,07715348 0,12247534 ! heart contraction GO:0060047 11 11 0,000 0,07715348 0,12236994 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07715348 0,12226472 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07715348 0,12215968 ! T cell proliferation GO:0042098 11 11 0,000 0,07715348 0,12205482 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07715348 0,12195014 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07715348 0,12184564 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07715348 0,12174132 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07715348 0,12163718 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07715348 0,12153322 ! fucose metabolic process GO:0006004 11 11 0,000 0,07715348 0,12142943 ! membrane budding GO:0006900 11 11 0,000 0,07715348 0,12132583 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,07715348 0,12122239 ! monoamine transport GO:0015844 11 11 0,000 0,07715348 0,12111914 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07715348 0,12101606 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07715348 0,12091315 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07715348 0,12081042 ! body fluid secretion GO:0007589 11 11 0,000 0,07715348 0,12070787 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,07715348 0,12060549 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07715348 0,12050328 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07715348 0,12040124 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07715348 0,12029938 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,07715348 0,12019769 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07715348 0,12009617 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07715348 0,11999482 ! oogenesis GO:0048477 11 11 0,000 0,07715348 0,11989365 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07715348 0,11979264 ! vitamin transport GO:0051180 11 11 0,000 0,07715348 0,11969181 ! muscle maintenance GO:0046716 12 11 0,000 0,07715348 0,11959114 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07715348 0,11949064 ! hindbrain development GO:0030902 11 11 0,000 0,07715348 0,11939032 ! steroid catabolic process GO:0006706 11 11 0,000 0,07715348 0,11929016 ! endocrine process GO:0050886 11 11 0,000 0,07715348 0,11919017 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07715348 0,11909034 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07715348 0,11899068 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07715348 0,11889119 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07715348 0,11879187 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,07849889 0,12076248 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,07849889 0,12066176 ! protein amino acid glycosylation GO:0006486 66 66 1,000 0,08277071 0,12712202 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,08387096 0,12870456 ! translational initiation GO:0006413 12 12 0,000 0,08387096 0,12859748 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08387096 0,12849058 ! initiation of viral infection GO:0019059 12 12 0,000 0,08387096 0,12838386 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,08387096 0,12827732 ! iron ion transport GO:0006826 13 12 0,000 0,08387096 0,12817095 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08387096 0,12806476 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08387096 0,12795875 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08387096 0,12785291 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08387096 0,12774725 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08387096 0,12764176 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08387096 0,12753644 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08387096 0,1274313 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08387096 0,12732634 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08387096 0,12722154 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08387096 0,12711692 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08387096 0,12701247 ! actomyosin structure organization GO:0031032 12 12 0,000 0,08387096 0,12690819 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08387096 0,12680408 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,08387096 0,12670014 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08387096 0,12659637 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08387096 0,12649278 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08387096 0,12638935 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08387096 0,12628609 ! acute-phase response GO:0006953 12 12 0,000 0,08387096 0,126183 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08387096 0,12608007 ! vacuolar transport GO:0007034 12 12 0,000 0,08387096 0,12597732 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08387096 0,12587473 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08387096 0,12577231 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08387096 0,12567006 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08387096 0,12556797 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,08387096 0,12546605 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08387096 0,12536429 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08387096 0,1252627 ! renal system process GO:0003014 12 12 0,000 0,08387096 0,12516127 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08387096 0,12506001 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08387096 0,12495891 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08387096 0,12485797 ! cell fate determination GO:0001709 12 12 0,000 0,08387096 0,1247572 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08387096 0,12465659 ! somitogenesis GO:0001756 13 12 0,000 0,08387096 0,12455614 ! G1 phase GO:0051318 13 12 0,000 0,08387096 0,12445585 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08387096 0,12435573 ! detection of light stimulus GO:0009583 13 12 0,000 0,08387096 0,12425576 ! synaptogenesis GO:0007416 12 12 0,000 0,08387096 0,12415596 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08387096 0,12405632 ! hormone transport GO:0009914 12 12 0,000 0,08387096 0,12395683 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08387096 0,12385751 ! spermatid differentiation GO:0048515 13 12 0,000 0,08387096 0,12375834 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08387096 0,12365934 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08387096 0,12356049 ! neural tube closure GO:0001843 13 12 0,000 0,08387096 0,1234618 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08387096 0,12336327 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,08387096 0,12326489 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,08493329 0,12472674 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,08493329 0,12462744 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,08493329 0,12452829 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,08493329 0,1244293 ! regionalization GO:0003002 70 69 1,000 0,08931 0,13073735 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,0905405 0,13243345 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,0905405 0,13232843 ! phenol metabolic process GO:0018958 13 13 0,000 0,0905405 0,13222357 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,0905405 0,13211888 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,0905405 0,13201436 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,0905405 0,13191 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,0905405 0,1318058 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,0905405 0,13170177 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,0905405 0,13159791 ! regeneration GO:0031099 13 13 0,000 0,0905405 0,13149421 ! keratinization GO:0031424 13 13 0,000 0,0905405 0,13139067 ! post-embryonic development GO:0009791 14 13 0,000 0,0905405 0,13128729 ! patterning of blood vessels GO:0001569 13 13 0,000 0,0905405 0,13118408 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,0905405 0,13108103 ! regulation of innate immune response GO:0045088 13 13 0,000 0,0905405 0,13097814 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,0905405 0,13087541 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,0905405 0,13077284 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,0905405 0,13067044 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,0905405 0,13056819 ! autophagy GO:0006914 13 13 0,000 0,0905405 0,1304661 ! receptor metabolic process GO:0043112 14 13 0,000 0,0905405 0,13036418 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,0905405 0,13026241 ! ureteric bud development GO:0001657 13 13 0,000 0,0905405 0,1301608 ! cell aging GO:0007569 13 13 0,000 0,0905405 0,13005935 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,0905405 0,12995806 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,0905405 0,12985692 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,0905405 0,12975595 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,0905405 0,12965513 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,0905405 0,12955446 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,0905405 0,12945395 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,0905405 0,1293536 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,0905405 0,12925341 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,0905405 0,12915336 ! vasodilation GO:0042311 14 13 0,000 0,0905405 0,12905348 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,0905405 0,12895375 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,0905405 0,12885417 ! neural crest cell migration GO:0001755 14 13 0,000 0,0905405 0,12875474 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,0905405 0,12865547 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,0905405 0,12855635 ! immunoglobulin production GO:0002377 13 13 0,000 0,0905405 0,12845739 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,0905405 0,12835857 ! cell-cell junction organization GO:0045216 13 13 0,000 0,0905405 0,12825991 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,0905405 0,1281614 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,0905405 0,12806304 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,0905405 0,12796484 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,0905405 0,12786678 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,0905405 0,12776887 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,0905405 0,12767111 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,0905405 0,12757351 GO:0033014|tetrapyrrole biosynthetic process, ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,0905405 0,12747605 ! blastocyst development GO:0001824 13 13 0,000 0,0905405 0,12737874 ! telomere organization GO:0032200 13 13 0,000 0,0905405 0,12728158 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,0905405 0,12718456 ! regulation of amine transport GO:0051952 13 13 0,000 0,0905405 0,1270877 ! tissue homeostasis GO:0001894 13 13 0,000 0,0905405 0,12699098 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,0905405 0,12689441 ! cell part morphogenesis GO:0032990 75 70 1,000 0,09152342 0,12817451 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,09375309 0,13119738 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 1,000 0,09599867 0,1342379 ! regulation of cytokine production GO:0001817 72 72 1,000 0,09599867 0,13413613 ! neuron fate commitment GO:0048663 14 14 0,000 0,09716246 0,1356594 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09716246 0,13555671 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09716246 0,13545417 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09716246 0,13535179 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09716246 0,13524956 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,09716246 0,13514748 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09716246 0,13504556 ! protein amino acid acylation GO:0043543 14 14 0,000 0,09716246 0,13494379 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09716246 0,13484218 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09716246 0,13474072 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09716246 0,13463941 ! vesicle docking GO:0048278 14 14 0,000 0,09716246 0,13453825 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09716246 0,13443725 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09716246 0,13433639 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09716246 0,13423569 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09716246 0,13413514 ! hair cycle GO:0042633 14 14 0,000 0,09716246 0,13403474 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09716246 0,13393449 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09716246 0,13383439 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09716246 0,13373444 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,09716246 0,13363464 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09716246 0,13353498 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09716246 0,13343548 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,09716246 0,13333612 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,09716246 0,13323691 ! primary neural tube formation GO:0014020 15 14 0,000 0,09716246 0,13313785 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09716246 0,13303894 ! base-excision repair GO:0006284 14 14 0,000 0,09716246 0,13294017 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,09716246 0,13284155 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09716246 0,13274308 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09716246 0,13264475 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09716246 0,13254657 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,09716246 0,13244853 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09716246 0,13235064 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,09716246 0,13225289 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09716246 0,13215529 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09716246 0,13205783 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09716246 0,13196051 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09716246 0,13186334 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09716246 0,13176631 ! electron transport chain GO:0022900 75 74 1,000 0,10053622 0,13624136 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,10373716 0,14047581 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,10373716 0,14037267 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10373716 0,14026969 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10373716 0,14016685 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,10373716 0,14006416 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10373716 0,13996163 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10373716 0,13985924 ! response to vitamin GO:0033273 15 15 0,000 0,10373716 0,139757 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,10373716 0,13965492 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10373716 0,13955298 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10373716 0,13945119 ! ovarian follicle development GO:0001541 15 15 0,000 0,10373716 0,13934955 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10373716 0,13924806 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10373716 0,13914671 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10373716 0,13904551 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10373716 0,13894446 ! heme metabolic process GO:0042168 15 15 0,000 0,10373716 0,13884356 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10373716 0,1387428 ! chromosome condensation GO:0030261 15 15 0,000 0,10373716 0,13864219 ! response to ionizing radiation GO:0010212 16 15 0,000 0,10373716 0,13854173 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10373716 0,13844141 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10373716 0,13834123 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10373716 0,1382412 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,10373716 0,13814132 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10373716 0,13804158 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10373716 0,13794198 ! phospholipid transport GO:0015914 15 15 0,000 0,10373716 0,13784252 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,10373716 0,13774321 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10373716 0,13764405 ! glutathione metabolic process GO:0006749 16 15 0,000 0,10373716 0,13754502 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10373716 0,13744614 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10373716 0,1373474 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,10373716 0,1372488 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10373716 0,13715035 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,10373716 0,13705203 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10373716 0,13695385 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10373716 0,13685582 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,10513341 0,13859862 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,10745356 0,14155604 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,10745356 0,14145493 ! metal ion homeostasis GO:0055065 78 78 1,000 0,10978765 0,14442443 ! regulation of immune response GO:0050776 78 78 1,000 0,10978765 0,14432142 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,11026493 0,14484552 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,11026493 0,14474235 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,11026493 0,14463933 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,11026493 0,14453646 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,11026493 0,14443373 ! circadian rhythm GO:0007623 16 16 0,000 0,11026493 0,14433115 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,11026493 0,14422872 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,11026493 0,14412643 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,11026493 0,14402428 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,11026493 0,14392228 ! vesicle targeting GO:0006903 17 16 0,000 0,11026493 0,14382043 ! segmentation GO:0035282 17 16 0,000 0,11026493 0,14371871 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,11026493 0,14361715 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,11026493 0,14351572 ! iron ion homeostasis GO:0055072 16 16 0,000 0,11026493 0,14341444 ! positive regulation of cell development GO:0010720 16 16 0,000 0,11026493 0,1433133 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,11026493 0,14321231 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,11026493 0,14311145 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,11026493 0,14301074 ! cell fate specification GO:0001708 16 16 0,000 0,11026493 0,14291017 ! pentose metabolic process GO:0019321 16 16 0,000 0,11026493 0,14280974 ! fatty acid transport GO:0015908 16 16 0,000 0,11026493 0,14270945 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,11026493 0,14260931 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,11026493 0,1425093 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,11026493 0,14240943 ! polyol metabolic process GO:0019751 16 16 0,000 0,11026493 0,14230971 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,11026493 0,14221012 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,11026493 0,14211067 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,11026493 0,14201136 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,11026493 0,14191219 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,11026493 0,14181316 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,11026493 0,14171427 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,11026493 0,14161551 ! glycoprotein biosynthetic process GO:0009101 80 80 1,000 0,1144964 0,14694767 ! neuron projection development GO:0031175 85 80 1,000 0,1144964 0,14684541 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,1167461 0,14962661 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,1167461 0,14952263 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,1167461 0,14941879 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,1167461 0,1493151 ! sensory perception of smell GO:0007608 17 17 0,000 0,1167461 0,14921155 ! glucose transport GO:0015758 17 17 0,000 0,1167461 0,14910815 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,1167461 0,14900489 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,1167461 0,14890177 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,1167461 0,1487988 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,1167461 0,14869596 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,1167461 0,14859327 ! neural crest cell development GO:0014032 19 17 0,000 0,1167461 0,14849072 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,1167461 0,14838832 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,1167461 0,14828605 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,1167461 0,14818392 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,1167461 0,14808194 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,1167461 0,1479801 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,1167461 0,14787839 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,1167461 0,14777683 ! embryonic organ development GO:0048568 17 17 0,000 0,1167461 0,1476754 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,1167461 0,14757411 ! gene silencing GO:0016458 17 17 0,000 0,1167461 0,14747297 ! lipid catabolic process GO:0016042 82 81 1,000 0,11687044 0,14752892 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12318099 0,15538848 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,12318099 0,1552822 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12318099 0,15517606 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12318099 0,15507006 ! membrane docking GO:0022406 18 18 0,000 0,12318099 0,15496421 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,12318099 0,15485851 GO:0070661|leukocyte proliferation, ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12318099 0,15475295 ! hexose transport GO:0008645 18 18 0,000 0,12318099 0,15464753 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,12318099 0,15454226 ! striated muscle contraction GO:0006941 18 18 0,000 0,12318099 0,15443712 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12318099 0,15433214 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,12318099 0,15422729 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,12318099 0,15412259 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12318099 0,15401803 ! B cell differentiation GO:0030183 18 18 0,000 0,12318099 0,15391361 ! BMP signaling pathway GO:0030509 18 18 0,000 0,12318099 0,15380933 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,12318099 0,1537052 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,12318099 0,1536012 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12318099 0,15349735 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,12892529 0,16054683 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 1,000 0,12892529 0,16043842 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,12956994 0,16113185 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,12956994 0,1610232 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,12956994 0,16091469 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,12956994 0,16080633 ! regulation of pH GO:0006885 19 19 0,000 0,12956994 0,16069812 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,12956994 0,16059005 ! feeding behavior GO:0007631 19 19 0,000 0,12956994 0,16048212 ! peroxisome organization GO:0007031 19 19 0,000 0,12956994 0,16037435 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,12956994 0,16026671 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,12956994 0,16015922 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,12956994 0,16005188 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,12956994 0,15994468 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,12956994 0,15983762 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,12956994 0,1597307 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,12956994 0,15962393 ! regulation of protein stability GO:0031647 19 19 0,000 0,12956994 0,1595173 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,12956994 0,15941082 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,12956994 0,15930447 ! vesicle localization GO:0051648 20 19 0,000 0,12956994 0,15919827 ! male gamete generation GO:0048232 90 88 1,000 0,13382793 0,16432037 GO:0007283|spermatogenesis, ! regulation of muscle development GO:0048634 21 20 0,000 0,13591326 0,16676973 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,13591326 0,16665877 ! negative regulation of binding GO:0051100 21 20 0,000 0,13591326 0,16654796 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13591326 0,1664373 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,13591326 0,16632678 ! neural tube development GO:0021915 21 20 0,000 0,13591326 0,16621641 ! nucleus organization GO:0006997 20 20 0,000 0,13591326 0,16610619 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,13591326 0,16599611 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13591326 0,16588618 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13591326 0,1657764 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13591326 0,16566676 ! chromatin remodeling GO:0006338 20 20 0,000 0,13591326 0,16555726 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13591326 0,16544791 ! lipid oxidation GO:0034440 20 20 0,000 0,13591326 0,1653387 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,13591326 0,16522964 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,13591326 0,16512072 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13591326 0,16501195 ! RNA modification GO:0009451 20 20 0,000 0,13591326 0,16490332 ! single fertilization GO:0007338 21 20 0,000 0,13591326 0,16479483 ! regulation of B cell activation GO:0050864 20 20 0,000 0,13591326 0,16468648 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,13629541 0,16504102 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,14126129 0,17094193 ! DNA replication GO:0006260 91 91 1,000 0,14126129 0,17082976 ! mRNA catabolic process GO:0006402 21 21 0,000 0,14221127 0,17186581 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,14221127 0,17175319 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,14221127 0,17164071 ! Notch signaling pathway GO:0007219 22 21 0,000 0,14221127 0,17152838 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,14221127 0,1714162 ! ear morphogenesis GO:0042471 21 21 0,000 0,14221127 0,17130416 ! organic anion transport GO:0015711 21 21 0,000 0,14221127 0,17119227 ! spliceosome assembly GO:0000245 22 21 0,000 0,14221127 0,17108053 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,14221127 0,17096893 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,14221127 0,17085747 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,14221127 0,17074617 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,14221127 0,170635 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,14221127 0,17052399 ! regulation of proteolysis GO:0030162 21 21 0,000 0,14221127 0,17041311 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,14221127 0,17030238 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,14221127 0,1701918 ! tissue morphogenesis GO:0048729 94 93 1,000 0,14626661 0,17493145 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,14846428 0,17744467 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,14846428 0,17732967 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,14846428 0,17721481 ! regulation of ion transport GO:0043269 22 22 0,000 0,14846428 0,17710011 ! odontogenesis GO:0042476 22 22 0,000 0,14846428 0,17698556 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,14846428 0,17687115 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,14846428 0,1767569 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,14846428 0,17664278 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,14846428 0,17652882 ! ovulation cycle process GO:0022602 22 22 0,000 0,14846428 0,17641501 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,14846428 0,17630134 ! cell chemotaxis GO:0060326 23 22 0,000 0,14846428 0,17618781 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,14846428 0,17607444 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,14846428 0,17596121 ! male sex differentiation GO:0046661 22 22 0,000 0,14846428 0,17584812 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,14846428 0,17573518 ! biopolymer methylation GO:0043414 22 22 0,000 0,14846428 0,17562238 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,14846428 0,17550973 ! detection of external stimulus GO:0009581 23 22 0,000 0,14846428 0,17539723 ! neuron migration GO:0001764 22 22 0,000 0,14846428 0,17528486 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,14846428 0,17517265 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,14846428 0,17506057 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,14846428 0,17494864 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,14846428 0,17483685 ! cytokine production GO:0001816 22 22 0,000 0,14846428 0,17472521 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,14846428 0,1746137 ! pattern specification process GO:0007389 96 94 1,000 0,1487834 0,17487742 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,15467262 0,18168365 ! viral infectious cycle GO:0019058 23 23 0,000 0,15467262 0,18156792 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,15467262 0,18145235 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,15467262 0,18133692 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,15467262 0,18122164 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,15467262 0,18110651 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,15467262 0,18099152 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,15467262 0,18087668 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,15467262 0,18076198 ! female gonad development GO:0008585 23 23 0,000 0,15467262 0,18064743 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,15467262 0,18053302 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,15467262 0,18041876 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,15467262 0,18030464 ! cell projection assembly GO:0030031 25 23 0,000 0,15467262 0,18019067 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,15893867 0,18504356 ! blood circulation GO:0008015 99 98 1,000 0,15893867 0,18492674 GO:0003013|circulatory system process, ! mitochondrial transport GO:0006839 24 24 0,000 0,1608366 0,18701694 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,1608366 0,18689902 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,1608366 0,18678125 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,1608366 0,18666363 ! T cell differentiation GO:0030217 24 24 0,000 0,1608366 0,18654616 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,1608366 0,18642883 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,1608366 0,18631166 ! ovulation cycle GO:0042698 24 24 0,000 0,1608366 0,18619463 ! fertilization GO:0009566 25 24 0,000 0,1608366 0,18607774 ! maintenance of protein location GO:0045185 25 24 0,000 0,1608366 0,18596101 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,1608366 0,18584442 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,1608366 0,18572797 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,1608366 0,18561168 ! anti-apoptosis GO:0006916 100 99 1,000 0,16149826 0,18625863 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,16406566 0,18910132 ! hemopoiesis GO:0030097 104 100 1,000 0,16406566 0,18898313 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,16695652 0,19219292 ! negative regulation of secretion GO:0051048 26 25 0,000 0,16695652 0,19207295 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,16695652 0,19195312 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,16695652 0,19183345 ! endosome transport GO:0016197 25 25 0,000 0,16695652 0,19171393 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,16695652 0,19159456 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,16695652 0,19147533 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,16695652 0,19135625 ! excretion GO:0007588 25 25 0,000 0,16695652 0,19123733 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,16695652 0,19111855 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,16695652 0,19099991 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,16695652 0,19088143 ! positive regulation of binding GO:0051099 27 26 0,000 0,17303269 0,19770567 ! positive regulation of defense response GO:0031349 26 26 0,000 0,17303269 0,19758318 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,17303269 0,19746083 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,17303269 0,19733864 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,17303269 0,1972166 ! cellular defense response GO:0006968 26 26 0,000 0,17303269 0,19709471 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,17303269 0,19697298 ! double-strand break repair GO:0006302 27 26 0,000 0,17303269 0,19685139 ! regulation of protein secretion GO:0050708 26 26 0,000 0,17303269 0,19672995 ! germ cell development GO:0007281 27 26 0,000 0,17303269 0,19660866 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,17303269 0,19648752 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,17303269 0,19636653 ! maintenance of location in cell GO:0051651 27 26 0,000 0,17303269 0,19624569 ! chloride transport GO:0006821 27 27 0,000 0,17906542 0,20296284 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,17906542 0,20283809 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,17906542 0,2027135 ! peptide metabolic process GO:0006518 29 27 0,000 0,17906542 0,20258906 ! activation of caspase activity GO:0006919 27 27 0,000 0,17906542 0,20246477 ! mesenchymal cell development GO:0014031 29 27 0,000 0,17906542 0,20234064 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,17906542 0,20221665 ! defense response to bacterium GO:0042742 27 27 0,000 0,17906542 0,20209282 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,17906542 0,20196914 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,17906542 0,20184561 ! cell growth GO:0016049 27 27 0,000 0,17906542 0,20172224 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,18505502 0,20834234 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,18505502 0,20821515 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 0,000 0,18505502 0,20808811 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,18505502 0,20796123 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,18505502 0,2078345 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,18505502 0,20770792 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,18505502 0,2075815 ! histone modification GO:0016570 28 28 0,000 0,18505502 0,20745524 ! developmental growth GO:0048589 28 28 0,000 0,18505502 0,20732912 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,19100179 0,21386167 ! leukocyte migration GO:0050900 30 29 0,000 0,19100179 0,21373182 ! antigen processing and presentation GO:0019882 29 29 0,000 0,19100179 0,21360213 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,19100179 0,21347259 ! tRNA processing GO:0008033 29 29 0,000 0,19100179 0,21334321 ! covalent chromatin modification GO:0016569 29 29 0,000 0,19100179 0,21321399 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,19100179 0,21308493 ! transition metal ion transport GO:0000041 31 30 0,000 0,19690603 0,2195389 ! RNA catabolic process GO:0006401 30 30 0,000 0,19690603 0,21940617 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,19690603 0,2192736 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,19690603 0,21914119 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,19690603 0,21900894 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,19690603 0,21887684 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,19690603 0,21874491 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,19690603 0,21861314 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,19690603 0,21848152 ! regulation of ossification GO:0030278 30 30 0,000 0,19690603 0,21835006 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,19690603 0,21821877 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,19690603 0,21808762 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,19690603 0,21795664 ! vesicle organization GO:0016050 30 30 0,000 0,19690603 0,21782581 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,19690603 0,21769514 ! regulation of translational initiation GO:0006446 31 31 0,000 0,20276803 0,22404165 ! membrane fusion GO:0006944 31 31 0,000 0,20276803 0,22390741 ! B cell activation GO:0042113 31 31 0,000 0,20276803 0,22377334 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,20276803 0,22363942 ! ion transmembrane transport GO:0034220 31 31 0,000 0,20276803 0,22350567 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,20276803 0,22337207 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,20276803 0,22323863 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,20276803 0,22310536 ! regulation of heart contraction GO:0008016 31 31 0,000 0,20276803 0,22297224 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,20276803 0,22283928 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,20276803 0,22270648 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,20858809 0,22896239 ! cell redox homeostasis GO:0045454 32 32 0,000 0,20858809 0,2288261 ! lipid modification GO:0030258 32 32 0,000 0,20858809 0,22868997 ! nuclear export GO:0051168 32 32 0,000 0,20858809 0,22855401 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,20858809 0,22841821 ! maintenance of location GO:0051235 33 32 0,000 0,20858809 0,22828257 ! negative regulation of cell size GO:0045792 33 33 0,000 0,2143665 0,23446734 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,2143665 0,23432827 ! amino acid transport GO:0006865 33 33 0,000 0,2143665 0,23418937 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,2143665 0,23405063 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,2143665 0,23391206 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,2143665 0,23377365 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,2143665 0,2336354 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,2143665 0,23349732 ! regulation of actin filament length GO:0030832 34 34 0,000 0,22010357 0,23960477 ! ear development GO:0043583 34 34 0,000 0,22010357 0,23946333 ! muscle cell differentiation GO:0042692 35 34 0,000 0,22010357 0,23932205 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,22010357 0,23918094 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,22010357 0,23904 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,22010357 0,23889922 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,22010357 0,23875861 ! secondary metabolic process GO:0019748 34 34 0,000 0,22010357 0,23861816 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,22010357 0,23847788 ! detection of stimulus GO:0051606 36 34 0,000 0,22010357 0,23833776 ! acute inflammatory response GO:0002526 35 35 0,000 0,22579957 0,24436207 ! regulation of cellular component size GO:0032535 35 35 0,000 0,22579957 0,24421866 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,22579957 0,24407543 ! mesoderm development GO:0007498 35 35 0,000 0,22579957 0,24393236 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,22579957 0,24378946 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,22579957 0,24364672 ! hydrogen transport GO:0006818 36 36 0,000 0,23145479 0,2496028 GO:0015992|proton transport, ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,23145479 0,24945683 ! female pregnancy GO:0007565 37 36 0,000 0,23145479 0,24931104 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,23145479 0,24916541 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,23145479 0,24901996 ! gonad development GO:0008406 36 36 0,000 0,23145479 0,24887467 ! activation of immune response GO:0002253 36 36 0,000 0,23145479 0,24872955 ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,23706953 0,25461489 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 0,000 0,23706953 0,2544666 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,23706953 0,25431848 ! negative regulation of growth GO:0045926 37 37 0,000 0,23706953 0,25417053 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,23706953 0,25402276 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,23706953 0,25387516 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,23706953 0,25372773 ! positive regulation of secretion GO:0051047 39 38 0,000 0,24264406 0,25954324 ! regulation of neurological system process GO:0031644 38 38 0,000 0,24264406 0,2593927 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,24264406 0,25924232 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,24817867 0,26500191 ! response to unfolded protein GO:0006986 39 39 0,000 0,24817867 0,26484846 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,24817867 0,26469519 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,24817867 0,2645421 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,24817867 0,26438919 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,24817867 0,26423645 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,24817867 0,26408389 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,25367364 0,26977526 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,25367364 0,26961968 ! amine catabolic process GO:0009310 42 41 0,000 0,25912924 0,27525948 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,25912924 0,27510092 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,25912924 0,27494254 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,25912924 0,27478434 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,26454576 0,28036678 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,26454576 0,28020565 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,26454576 0,2800447 ! protein ubiquitination GO:0016567 43 42 0,000 0,26454576 0,27988394 ! response to protein stimulus GO:0051789 42 42 0,000 0,26454576 0,27972337 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,26454576 0,27956297 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,26992345 0,28508248 ! mitochondrion organization GO:0007005 44 43 0,000 0,26992345 0,2849192 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,26992345 0,28475611 ! humoral immune response GO:0006959 44 44 0,000 0,27526261 0,29022254 ! mRNA transport GO:0051028 44 44 0,000 0,27526261 0,2900566 ! protein import into nucleus GO:0006606 44 44 0,000 0,27526261 0,28989086 ! vitamin metabolic process GO:0006766 44 44 0,000 0,27526261 0,2897253 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,27526261 0,28955993 ! amine biosynthetic process GO:0009309 46 45 0,000 0,2805635 0,29496779 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,2805635 0,29479962 ! regulation of DNA binding GO:0051101 47 45 0,000 0,2805635 0,29463164 ! nuclear import GO:0051170 45 45 0,000 0,2805635 0,29446386 ! protein processing GO:0016485 45 45 0,000 0,2805635 0,29429626 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,28582639 0,29964621 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,28582639 0,29947586 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,29105154 0,30477726 ! regulation of blood pressure GO:0008217 48 47 0,000 0,29105154 0,30460419 ! sex differentiation GO:0007548 47 47 0,000 0,29105154 0,30443132 ! amine transport GO:0015837 47 47 0,000 0,29105154 0,30425864 ! protein localization in nucleus GO:0034504 48 48 0,000 0,29623922 0,30950617 ! DNA recombination GO:0006310 48 48 0,000 0,29623922 0,30933081 ! leukocyte differentiation GO:0002521 50 49 0,000 0,30138969 0,31453069 ! response to nutrient GO:0007584 49 49 0,000 0,30138969 0,31435269 ! response to bacterium GO:0009617 50 49 0,000 0,30138969 0,31417489 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,30138969 0,31399729 ! chromatin assembly GO:0031497 50 50 0,000 0,30650322 0,31914432 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,30650322 0,31896411 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,30650322 0,31878411 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,30650322 0,31860431 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,30650322 0,31842471 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,30650322 0,31824532 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,31158006 0,32333449 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,31158006 0,32315254 ! positive regulation of immune response GO:0050778 51 51 0,000 0,31158006 0,32297079 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,31158006 0,32278924 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,31158006 0,3226079 ! protein maturation GO:0051604 51 51 0,000 0,31158006 0,32242676 ! RNA localization GO:0006403 52 52 0,000 0,31662048 0,32745878 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,31662048 0,32727512 ! cell fate commitment GO:0045165 52 52 0,000 0,31662048 0,32709167 ! sodium ion transport GO:0006814 53 53 0,000 0,32162472 0,33207528 ! tRNA metabolic process GO:0006399 53 53 0,000 0,32162472 0,33188934 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,32162472 0,33170362 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,32162472 0,3315181 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,32659305 0,33645109 ! response to virus GO:0009615 54 54 0,000 0,32659305 0,33626312 ! sulfur metabolic process GO:0006790 55 54 0,000 0,32659305 0,33607537 ! nucleosome organization GO:0034728 55 55 0,000 0,33152571 0,34096087 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,33152571 0,34077071 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,33152571 0,34058076 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,33152571 0,34039102 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,33642296 0,3452269 ! regulation of binding GO:0051098 60 57 0,000 0,34128504 0,35002133 ! ATP metabolic process GO:0046034 57 57 0,000 0,34128504 0,34982666 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,34128504 0,3496322 ! innate immune response GO:0045087 58 58 0,000 0,34611221 0,35438044 ! dephosphorylation GO:0016311 60 59 0,000 0,3509047 0,35908793 ! carboxylic acid transport GO:0046942 59 59 0,000 0,3509047 0,35888866 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,3509047 0,35868961 ! protein localization in organelle GO:0033365 59 59 0,000 0,3509047 0,35849078 ! immune effector process GO:0002252 59 59 0,000 0,3509047 0,35829217 ! potassium ion transport GO:0006813 60 60 0,000 0,35566277 0,36294932 ! protein polymerization GO:0051258 65 60 0,000 0,35566277 0,36274847 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,36038665 0,36736316 GO:0016054|organic acid catabolic process, ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,36507658 0,37193816 ! protein import GO:0017038 62 62 0,000 0,36507658 0,37173267 ! regulation of secretion GO:0051046 65 63 0,000 0,36973281 0,37626591 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,36973281 0,37605826 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,36973281 0,37585084 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,37435557 0,38034031 ! anion transport GO:0006820 65 65 0,000 0,3789451 0,38479108 ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,38350163 0,38920347 ! DNA packaging GO:0006323 66 66 0,000 0,38350163 0,38898927 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,38802539 0,39336127 ! muscle contraction GO:0006936 67 67 0,000 0,38802539 0,39314502 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,39251662 0,39747699 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,39251662 0,39725872 ! regulation of cell size GO:0008361 68 68 0,000 0,39251662 0,39704068 ! growth GO:0040007 70 70 0,000 0,40140238 0,40580614 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,40140238 0,40558366 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,40579737 0,40979976 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,40579737 0,40957533 ! muscle system process GO:0003012 72 72 0,000 0,41016073 0,41375273 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,42306327 0,4265348 ! response to oxidative stress GO:0006979 76 75 0,000 0,42306327 0,42630159 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,42306327 0,42606864 ! microtubule-based movement GO:0007018 82 78 0,000 0,4356891 0,43854452 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,4356891 0,43830514 ! nuclear transport GO:0051169 79 79 0,000 0,43983722 0,44223677 GO:0006913|nucleocytoplasmic transport, ! lymphocyte activation GO:0046649 82 81 0,000 0,44804402 0,45024271 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,45613296 0,45812155 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,46013375 0,46188807 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,46410569 0,46562155 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,46410569 0,46536822 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,47585047 0,47688549 ! chemotaxis GO:0006935 90 89 0,000 0,47970905 0,48049118 GO:0042330|taxis, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,49111852 0,49165206 ! regulation of system process GO:0044057 98 98 0,000 0,51320674 0,51348536 ! response to other organism GO:0051707 101 100 0,000 0,52035853 0,52035853