pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6880-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 10,000 3,521E-13 8,471E-10 ! negative regulation of ligase activity GO:0051352 112 68 10,000 4,178E-13 5,026E-10 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 10,000 4,178E-13 3,35E-10 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 10,000 8,062E-13 4,849E-10 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 10,000 2,322E-12 1,117E-09 ! regulation of ligase activity GO:0051340 142 84 10,000 4,647E-12 1,863E-09 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 10,000 1,454E-11 4,996E-09 GO:0010498|proteasomal protein catabolic process, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 8,000 4,433E-10 1,333E-07 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 8,000 6,553E-10 1,752E-07 ! positive regulation of ligase activity GO:0051351 124 77 8,000 1,21E-09 2,91E-07 ! acetyl-CoA metabolic process GO:0006084 39 26 5,000 1,063E-08 2,326E-06 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 3,000 9,671E-08 1,939E-05 ! positive regulation of locomotion GO:0040017 39 21 4,000 1,599E-07 2,959E-05 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,732E-07 2,977E-05 ! regulation of chemotaxis GO:0050920 40 22 4,000 2,059E-07 3,302E-05 ! acetyl-CoA catabolic process GO:0046356 36 23 4,000 2,617E-07 3,936E-05 GO:0006099|tricarboxylic acid cycle, ! regulation of behavior GO:0050795 43 24 4,000 3,29E-07 4,656E-05 ! coenzyme catabolic process GO:0009109 39 25 4,000 4,091E-07 5,469E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 6,708E-07 8,494E-05 GO:0050927|positive regulation of positive chemotaxis, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 3,000 6,708E-07 8,069E-05 ! negative regulation of protein modification process GO:0031400 60 28 4,000 7,456E-07 8,542E-05 ! cofactor catabolic process GO:0051187 51 30 4,000 1,07E-06 1,17E-04 ! negative regulation of cell motion GO:0051271 134 55 5,000 1,154E-06 1,207E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 1,343E-06 1,347E-04 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 2,000 2,297E-06 2,211E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 2,297E-06 2,126E-04 ! aerobic respiration GO:0009060 55 36 4,000 2,748E-06 2,448E-04 ! positive regulation of cell motion GO:0051272 146 64 5,000 2,85E-06 2,449E-04 ! regulation of endothelial cell migration GO:0010594 44 19 3,000 5,077E-06 4,212E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 6,774E-06 5,433E-04 ! collagen fibril organization GO:0030199 59 21 3,000 7,765E-06 6,026E-04 ! wound healing, spreading of epidermal cells GO:0035313 14 7 2,000 7,966E-06 5,99E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 7,966E-06 5,808E-04 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 2,000 1,269E-05 8,978E-04 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 1,269E-05 8,722E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,359E-05 9,081E-04 ! myelination GO:0042552 45 25 3,000 1,61E-05 1,047E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,893E-05 1,199E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 1,893E-05 1,168E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,893E-05 1,139E-03 GO:0045936|negative regulation of phosphate metabolic process, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 2,212E-05 1,298E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 2,499E-05 1,431E-03 ! regulation of bone resorption GO:0045124 25 10 2,000 2,694E-05 1,507E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,694E-05 1,473E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 2,694E-05 1,44E-03 ! positive regulation of cell migration GO:0030335 126 57 4,000 2,748E-05 1,437E-03 ! ensheathment of neurons GO:0007272 57 30 3,000 3,404E-05 1,743E-03 GO:0008366|axon ensheathment, ! chondrocyte differentiation GO:0002062 24 11 2,000 3,688E-05 1,848E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 3,688E-05 1,811E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,688E-05 1,774E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 4,424E-05 2,087E-03 ! regulation of RNA splicing GO:0043484 20 12 2,000 4,894E-05 2,265E-03 ! mitotic sister chromatid segregation GO:0000070 57 36 3,000 7,108E-05 3,227E-03 ! sister chromatid segregation GO:0000819 58 37 3,000 7,932E-05 3,534E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 7,932E-05 3,47E-03 ! regulation of mRNA processing GO:0050684 24 14 2,000 8,025E-05 3,448E-03 ! intestinal absorption GO:0050892 25 14 2,000 8,025E-05 3,387E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 8,822E-05 3,66E-03 GO:0042593|glucose homeostasis, ! regulation of action potential in neuron GO:0019228 73 39 3,000 9,783E-05 3,99E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 9,985E-05 4,004E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 2,000 1,223E-04 4,825E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,312E-04 5,092E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 1,325E-04 5,062E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,479E-04 5,559E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,479E-04 5,474E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,479E-04 5,391E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 1,492E-04 5,357E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 4,000 1,492E-04 5,278E-03 ! response to oxygen levels GO:0070482 176 83 4,000 1,674E-04 5,836E-03 ! glycolysis GO:0006096 65 45 3,000 1,722E-04 5,918E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,766E-04 5,986E-03 ! negative regulation of transport GO:0051051 153 84 4,000 1,771E-04 5,918E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,877E-04 6,185E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 1,877E-04 6,102E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,877E-04 6,02E-03 ! alcohol catabolic process GO:0046164 130 86 4,000 1,978E-04 6,262E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 2,088E-04 6,525E-03 ! cellular respiration GO:0045333 135 88 4,000 2,203E-04 6,795E-03 ! regulation of action potential GO:0001508 95 49 3,000 2,402E-04 7,315E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,445E-04 7,355E-03 ! cellular response to starvation GO:0009267 33 20 2,000 2,445E-04 7,264E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,445E-04 7,175E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,445E-04 7,089E-03 GO:0010827|regulation of glucose transport, ! negative regulation of translation GO:0017148 29 20 2,000 2,445E-04 7,005E-03 ! ossification GO:0001503 188 90 4,000 2,447E-04 6,926E-03 ! bone development GO:0060348 189 91 4,000 2,576E-04 7,208E-03 ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 2,84E-04 7,854E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,84E-04 7,765E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,84E-04 7,678E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 3,025E-04 8,087E-03 ! cartilage development GO:0051216 90 52 3,000 3,025E-04 7,998E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 2,000 3,274E-04 8,561E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,274E-04 8,469E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,274E-04 8,379E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 3,274E-04 8,291E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 3,748E-04 9,393E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 3,748E-04 9,296E-03 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,748E-04 9,201E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,748E-04 9,108E-03 ! cell migration involved in gastrulation GO:0042074 7 5 1,000 3,748E-04 9,017E-03 ! apoptotic cell clearance GO:0043277 20 5 1,000 3,748E-04 8,928E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 3,748E-04 8,84E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,748E-04 8,754E-03 ! smooth muscle tissue development GO:0048745 28 5 1,000 3,748E-04 8,67E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,748E-04 8,588E-03 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 1,000 3,748E-04 8,506E-03 ! polyol catabolic process GO:0046174 7 5 1,000 3,748E-04 8,427E-03 GO:0019405|alditol catabolic process, ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,748E-04 8,349E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,748E-04 8,272E-03 ! lipoprotein catabolic process GO:0042159 11 5 1,000 3,748E-04 8,197E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 3,748E-04 8,123E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,748E-04 8,051E-03 ! forebrain morphogenesis GO:0048853 13 5 1,000 3,748E-04 7,98E-03 ! metaphase plate congression GO:0051310 7 5 1,000 3,748E-04 7,91E-03 ! metaphase GO:0051323 8 5 1,000 3,748E-04 7,841E-03 ! positive regulation of blood coagulation GO:0030194 11 5 1,000 3,748E-04 7,773E-03 ! positive regulation of macrophage activation GO:0043032 12 5 1,000 3,748E-04 7,707E-03 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 3,748E-04 7,641E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 3,748E-04 7,577E-03 GO:0022011|myelination in the peripheral nervous system, ! glucose catabolic process GO:0006007 82 55 3,000 3,756E-04 7,531E-03 ! vacuole organization GO:0007033 43 24 2,000 4,264E-04 8,478E-03 ! digestive system process GO:0022600 39 24 2,000 4,264E-04 8,408E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 4,309E-04 8,428E-03 ! response to starvation GO:0042594 42 25 2,000 4,823E-04 9,358E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 4,823E-04 9,283E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 5,243E-04 0,01001192 ! pyruvate metabolic process GO:0006090 38 26 2,000 5,427E-04 0,01028224 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 5,427E-04 0,01020191 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 5,427E-04 0,01012282 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 5,584E-04 0,01033514 ! malate metabolic process GO:0006108 11 6 1,000 5,599E-04 0,01028267 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 5,599E-04 0,01020477 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 1,000 5,599E-04 0,01012805 ! male sex determination GO:0030238 15 6 1,000 5,599E-04 0,01005246 ! establishment of spindle localization GO:0051293 12 6 1,000 5,599E-04 9,978E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 5,599E-04 9,905E-03 GO:0045686|negative regulation of glial cell differentiation, ! astrocyte development GO:0014002 15 6 1,000 5,599E-04 9,832E-03 ! Schwann cell development GO:0014044 15 6 1,000 5,599E-04 9,761E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 5,599E-04 9,691E-03 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 1,000 5,599E-04 9,622E-03 ! positive regulation of coagulation GO:0050820 12 6 1,000 5,599E-04 9,553E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 6,777E-04 0,01148239 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 7,525E-04 0,01266016 ! extracellular matrix organization GO:0030198 133 66 3,000 7,53E-04 0,01258062 ! prostate gland development GO:0030850 13 7 1,000 7,806E-04 0,01295293 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,806E-04 0,01286422 ! mRNA stabilization GO:0048255 18 7 1,000 7,806E-04 0,0127767 GO:0043489|RNA stabilization, ! fibril organization GO:0043206 16 7 1,000 7,806E-04 0,01269038 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,806E-04 0,0126052 ! estrogen metabolic process GO:0008210 17 7 1,000 7,806E-04 0,01252117 ! adrenal gland development GO:0030325 17 7 1,000 7,806E-04 0,01243825 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 7,806E-04 0,01235642 ! spindle checkpoint GO:0031577 15 7 1,000 7,806E-04 0,01227566 ! negative regulation of focal adhesion formation GO:0051895 20 7 1,000 7,806E-04 0,01219594 ! regulation of lipid transport GO:0032368 14 7 1,000 7,806E-04 0,01211726 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,806E-04 0,01203959 ! anaphase GO:0051322 17 7 1,000 7,806E-04 0,0119629 GO:0000090|mitotic anaphase, ! negative regulation of nuclear division GO:0051784 14 7 1,000 7,806E-04 0,01188719 GO:0045839|negative regulation of mitosis, ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 7,806E-04 0,01181242 GO:0002688|regulation of leukocyte chemotaxis, ! glycolipid catabolic process GO:0019377 15 7 1,000 7,806E-04 0,0117386 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 7,969E-04 0,01190946 ! chromosome segregation GO:0007059 113 67 3,000 7,969E-04 0,01183594 ! hexose catabolic process GO:0019320 104 67 3,000 7,969E-04 0,01176333 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 7,969E-04 0,0116916 ! cell junction assembly GO:0034329 78 30 2,000 8,323E-04 0,01213611 ! eye morphogenesis GO:0048592 60 30 2,000 8,323E-04 0,012063 ! negative regulation of kinase activity GO:0033673 131 68 3,000 8,427E-04 0,01214086 ! spindle organization GO:0007051 46 32 2,000 1,008E-03 0,01443022 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,008E-03 0,01434484 ! peripheral nervous system development GO:0007422 64 32 2,000 1,008E-03 0,01426046 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,037E-03 0,01458514 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 1,037E-03 0,01450034 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 1,000 1,037E-03 0,01441652 ! oligopeptide transport GO:0006857 15 8 1,000 1,037E-03 0,01433367 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,037E-03 0,01425176 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,037E-03 0,01417079 ! ganglioside metabolic process GO:0001573 19 8 1,000 1,037E-03 0,01409073 ! regulation of defense response to virus by virus GO:0050690 18 8 1,000 1,037E-03 0,01401156 ! astrocyte differentiation GO:0048708 18 8 1,000 1,037E-03 0,01393329 ! ER overload response GO:0006983 12 8 1,000 1,037E-03 0,01385588 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,037E-03 0,01377933 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,037E-03 0,01370362 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,037E-03 0,01362873 ! regulation of focal adhesion formation GO:0051893 22 8 1,000 1,037E-03 0,01355467 ! establishment of chromosome localization GO:0051303 12 8 1,000 1,037E-03 0,0134814 GO:0050000|chromosome localization, ! regulation of macrophage activation GO:0043030 15 8 1,000 1,037E-03 0,01340892 ! neuromuscular process controlling posture GO:0050884 14 8 1,000 1,037E-03 0,01333721 ! negative regulation of organic acid transport GO:0032891 13 8 1,000 1,037E-03 0,01326627 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 1,000 1,037E-03 0,01319608 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,037E-03 0,01312662 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 1,044E-03 0,0131556 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,044E-03 0,01308708 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,103E-03 0,01375467 GO:0060326|cell chemotaxis, ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 1,216E-03 0,01508404 ! monosaccharide catabolic process GO:0046365 115 76 3,000 1,278E-03 0,0157648 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,312E-03 0,01610102 ! regulation of developmental growth GO:0048638 15 9 1,000 1,327E-03 0,01621129 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,327E-03 0,01612941 ! artery development GO:0060840 24 9 1,000 1,327E-03 0,01604836 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 1,000 1,327E-03 0,01596812 ! microtubule bundle formation GO:0001578 21 9 1,000 1,327E-03 0,01588867 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,327E-03 0,01581002 ! intestinal cholesterol absorption GO:0030299 16 9 1,000 1,327E-03 0,01573213 ! motor axon guidance GO:0008045 16 9 1,000 1,327E-03 0,01565502 ! protein heterooligomerization GO:0051291 16 9 1,000 1,327E-03 0,01557865 ! regulation of fibrinolysis GO:0051917 16 9 1,000 1,327E-03 0,01550303 ! negative regulation of organelle organization GO:0010639 161 78 3,000 1,407E-03 0,01635421 ! cell junction organization GO:0034330 86 36 2,000 1,424E-03 0,01647665 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,652E-03 0,01902308 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,652E-03 0,01893249 ! lung alveolus development GO:0048286 26 10 1,000 1,652E-03 0,01884277 ! epithelial cell development GO:0002064 20 10 1,000 1,652E-03 0,01875389 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,652E-03 0,01866584 GO:0045685|regulation of glial cell differentiation, ! phagocytosis, engulfment GO:0006911 28 10 1,000 1,652E-03 0,01857862 ! brain morphogenesis GO:0048854 23 10 1,000 1,652E-03 0,0184922 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,652E-03 0,01840659 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,652E-03 0,01832177 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,652E-03 0,01823772 ! localization within membrane GO:0051668 20 10 1,000 1,652E-03 0,01815445 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,668E-03 0,01823971 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,668E-03 0,01815718 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,693E-03 0,01834426 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 1,936E-03 0,02088471 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,011E-03 0,02160547 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,011E-03 0,02150944 ! blood vessel remodeling GO:0001974 29 11 1,000 2,011E-03 0,02141427 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,011E-03 0,02131993 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,011E-03 0,02122642 ! lipid digestion GO:0044241 18 11 1,000 2,011E-03 0,02113373 ! adult heart development GO:0007512 14 11 1,000 2,011E-03 0,02104184 ! regulation of organic acid transport GO:0032890 18 11 1,000 2,011E-03 0,02095075 ! regulation of embryonic development GO:0045995 27 11 1,000 2,011E-03 0,02086045 ! regulation of protein transport GO:0051223 154 87 3,000 2,103E-03 0,02171841 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 3,000 2,193E-03 0,02254752 ! regulation of cell adhesion GO:0030155 212 89 3,000 2,285E-03 0,02339622 ! epithelial cell differentiation GO:0030855 79 43 2,000 2,385E-03 0,02431799 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,385E-03 0,02421539 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,404E-03 0,02430251 ! virus-host interaction GO:0019048 29 12 1,000 2,404E-03 0,02420083 ! cartilage condensation GO:0001502 20 12 1,000 2,404E-03 0,02409999 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,404E-03 0,02399999 ! drug transport GO:0015893 16 12 1,000 2,404E-03 0,02390082 ! focal adhesion formation GO:0048041 35 12 1,000 2,404E-03 0,02380246 ! negative regulation of endothelial cell migration GO:0010596 25 12 1,000 2,404E-03 0,02370491 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,404E-03 0,02360815 ! autonomic nervous system development GO:0048483 24 12 1,000 2,404E-03 0,02351218 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,404E-03 0,02341699 GO:0042130|negative regulation of T cell proliferation, ! regulation of defense response GO:0031347 149 92 3,000 2,578E-03 0,02501031 ! regulation of membrane potential GO:0042391 164 93 3,000 2,681E-03 0,02590561 ! leukocyte migration GO:0050900 68 45 2,000 2,718E-03 0,02615833 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,718E-03 0,02605411 ! lipid localization GO:0010876 28 13 1,000 2,83E-03 0,02701558 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 2,83E-03 0,0269088 ! plasma membrane organization GO:0007009 24 13 1,000 2,83E-03 0,02680286 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,83E-03 0,02669775 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,83E-03 0,02659346 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! ribosome assembly GO:0042255 17 13 1,000 2,83E-03 0,02648998 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,83E-03 0,02638731 ! gastrulation with mouth forming second GO:0001702 25 13 1,000 2,83E-03 0,02628543 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 2,83E-03 0,02618433 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,83E-03 0,02608401 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,83E-03 0,02598445 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 2,000 2,895E-03 0,02648034 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,895E-03 0,02638004 ! pigmentation GO:0043473 100 46 2,000 2,895E-03 0,02628049 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,895E-03 0,02618169 ! positive regulation of defense response GO:0031349 76 47 2,000 3,078E-03 0,02773664 ! response to calcium ion GO:0051592 81 47 2,000 3,078E-03 0,02763314 ! positive regulation of cyclase activity GO:0031281 103 47 2,000 3,078E-03 0,02753042 ! regulation of protein localization GO:0032880 176 97 3,000 3,121E-03 0,02781578 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,268E-03 0,02901788 ! positive regulation of lyase activity GO:0051349 104 48 2,000 3,268E-03 0,02891119 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,268E-03 0,02880529 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 3,288E-03 0,02887008 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 3,288E-03 0,0287651 ! regulation of RNA stability GO:0043487 32 14 1,000 3,288E-03 0,02866088 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 3,466E-03 0,03010476 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,671E-03 0,03176761 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,778E-03 0,03258217 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,778E-03 0,03246581 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,778E-03 0,03235027 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! response to hexose stimulus GO:0009746 22 15 1,000 3,778E-03 0,03223555 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 3,882E-03 0,03300766 ! regulation of muscle contraction GO:0006937 81 52 2,000 4,102E-03 0,03474831 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,301E-03 0,0363053 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,301E-03 0,03617836 ! regulation of defense response to virus GO:0050688 27 16 1,000 4,301E-03 0,0360523 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,301E-03 0,03592712 GO:0031114|regulation of microtubule depolymerization, ! embryonic digit morphogenesis GO:0042733 34 16 1,000 4,301E-03 0,0358028 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,301E-03 0,03567935 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,301E-03 0,03555674 ! sphingolipid catabolic process GO:0030149 27 16 1,000 4,301E-03 0,03543497 GO:0046466|membrane lipid catabolic process, ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,301E-03 0,03531403 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,301E-03 0,03519391 ! activation of phospholipase C activity GO:0007202 103 54 2,000 4,562E-03 0,03720901 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 4,804E-03 0,03904658 ! RNA elongation GO:0006354 79 55 2,000 4,804E-03 0,03891511 ! glial cell development GO:0021782 27 17 1,000 4,854E-03 0,03919186 ! adult walking behavior GO:0007628 33 17 1,000 4,854E-03 0,03906078 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,854E-03 0,03893058 ! aromatic compound biosynthetic process GO:0019438 24 17 1,000 4,854E-03 0,03880124 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,854E-03 0,03867276 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,854E-03 0,03854513 ! regulation of DNA replication GO:0006275 101 56 2,000 5,053E-03 0,03999071 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 5,31E-03 0,04188518 ! regulation of bone remodeling GO:0046850 137 57 2,000 5,31E-03 0,04174831 ! regulation of phospholipase activity GO:0010517 106 57 2,000 5,31E-03 0,04161232 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,439E-03 0,04248683 ! memory GO:0007613 31 18 1,000 5,439E-03 0,04234933 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 5,439E-03 0,04221272 ! porphyrin biosynthetic process GO:0006779 33 18 1,000 5,439E-03 0,04207699 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,439E-03 0,04194213 ! regulation of tissue remodeling GO:0034103 140 58 2,000 5,574E-03 0,04284777 ! positive regulation of lipase activity GO:0060193 108 58 2,000 5,574E-03 0,04271132 ! DNA catabolic process GO:0006308 86 59 2,000 5,846E-03 0,04465537 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 5,846E-03 0,04451405 ! establishment of organelle localization GO:0051656 109 59 2,000 5,846E-03 0,04437363 ! positive regulation of translation GO:0045727 30 19 1,000 6,054E-03 0,04580616 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 6,054E-03 0,04566257 ! skin development GO:0043588 36 19 1,000 6,054E-03 0,04551988 ! lipid phosphorylation GO:0046834 35 19 1,000 6,054E-03 0,04537807 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 6,054E-03 0,04523714 ! cerebral cortex development GO:0021987 36 19 1,000 6,054E-03 0,04509709 ! pigmentation during development GO:0048066 41 19 1,000 6,054E-03 0,0449579 ! neuromuscular junction development GO:0007528 34 19 1,000 6,054E-03 0,04481957 ! peptide cross-linking GO:0018149 37 19 1,000 6,054E-03 0,04468209 ! visual learning GO:0008542 36 19 1,000 6,054E-03 0,04454544 ! regulation of heart contraction GO:0008016 110 60 2,000 6,127E-03 0,0449402 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 6,127E-03 0,0448036 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,7E-03 0,04884688 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to carbohydrate stimulus GO:0009743 29 20 1,000 6,7E-03 0,0486993 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 6,7E-03 0,04855262 ! peptidyl-serine modification GO:0018209 43 20 1,000 6,7E-03 0,04840681 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 6,7E-03 0,04826188 ! negative regulation of T cell activation GO:0050868 40 20 1,000 6,7E-03 0,04811782 ! regulation of homeostatic process GO:0032844 134 62 2,000 6,71E-03 0,04805175 ! regulation of mitosis GO:0007088 105 63 2,000 7,014E-03 0,05007926 GO:0051783|regulation of nuclear division, ! glycerol metabolic process GO:0006071 34 21 1,000 7,375E-03 0,052498 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 7,375E-03 0,05234314 ! actin filament organization GO:0007015 148 66 2,000 7,975E-03 0,05643358 ! lysosome organization GO:0007040 41 22 1,000 8,08E-03 0,05700878 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 8,08E-03 0,05684209 ! activation of MAPK activity GO:0000187 115 67 2,000 8,311E-03 0,05830014 ! lung development GO:0030324 144 67 2,000 8,311E-03 0,05813067 ! regulation of lipase activity GO:0060191 130 68 2,000 8,656E-03 0,06036611 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,814E-03 0,06128771 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 8,814E-03 0,06111109 ! gluconeogenesis GO:0006094 33 23 1,000 8,814E-03 0,06093548 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 8,814E-03 0,06076088 ! protein amino acid O-linked glycosylation GO:0006493 42 23 1,000 8,814E-03 0,06058728 ! leukocyte adhesion GO:0007159 50 23 1,000 8,814E-03 0,06041466 ! visual behavior GO:0007632 42 23 1,000 8,814E-03 0,06024303 ! sex determination GO:0007530 47 23 1,000 8,814E-03 0,06007237 ! glycosphingolipid metabolic process GO:0006687 41 23 1,000 8,814E-03 0,05990268 ! negative regulation of cytokine production GO:0001818 40 23 1,000 8,814E-03 0,05973394 ! cell cycle checkpoint GO:0000075 137 69 2,000 9,009E-03 0,0608865 ! urogenital system development GO:0001655 137 69 2,000 9,009E-03 0,06071595 ! respiratory tube development GO:0030323 150 70 2,000 9,37E-03 0,06297459 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 9,576E-03 0,06417846 ! spinal cord development GO:0021510 47 24 1,000 9,576E-03 0,06400019 ! pallium development GO:0021543 49 24 1,000 9,576E-03 0,0638229 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 9,576E-03 0,0636466 ! porphyrin metabolic process GO:0006778 46 24 1,000 9,576E-03 0,06347126 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 1,000 9,576E-03 0,06329689 ! regulation of multi-organism process GO:0043900 36 24 1,000 9,576E-03 0,06312347 ! protein tetramerization GO:0051262 52 24 1,000 9,576E-03 0,062951 ! regulation of transmembrane transport GO:0034762 38 24 1,000 9,576E-03 0,06277948 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 0,01011803 0,06615209 ! respiratory system development GO:0060541 153 72 2,000 0,01011803 0,06597282 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01036685 0,06741255 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 0,01036685 0,06723085 ! vasculogenesis GO:0001570 46 25 1,000 0,01036685 0,06705012 ! osteoblast differentiation GO:0001649 60 25 1,000 0,01036685 0,06687036 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01036685 0,06669156 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01036685 0,06651372 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 0,01036685 0,06633682 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01036685 0,06616086 ! regulation of blood coagulation GO:0030193 40 25 1,000 0,01036685 0,06598583 ! neuromuscular process controlling balance GO:0050885 60 25 1,000 0,01036685 0,06581173 ! liver development GO:0001889 53 25 1,000 0,01036685 0,06563854 ! learning or memory GO:0007611 147 73 2,000 0,01050453 0,06633568 ! eye development GO:0001654 143 74 2,000 0,0108995 0,06864972 ! organelle localization GO:0051640 136 74 2,000 0,0108995 0,06847048 ! macromolecular complex disassembly GO:0032984 53 26 1,000 0,01118553 0,07008432 ! regulation of response to biotic stimulus GO:0002831 44 26 1,000 0,01118553 0,06990228 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01118553 0,06972119 GO:0045840|positive regulation of mitosis, ! cell-matrix adhesion GO:0007160 163 75 2,000 0,01130297 0,07027116 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01203174 0,07460921 ! glycolipid metabolic process GO:0006664 47 27 1,000 0,01203174 0,07441742 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01203174 0,0742266 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01203174 0,07403676 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,01256466 0,0771188 ! protein oligomerization GO:0051259 139 78 2,000 0,01256466 0,07692257 ! dendrite development GO:0016358 59 28 1,000 0,01290513 0,07880647 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01290513 0,07860696 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 0,01344879 0,0817116 ! response to metal ion GO:0010038 140 80 2,000 0,01344879 0,08150577 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01380533 0,08345635 ! regulation of coagulation GO:0050818 46 29 1,000 0,01380533 0,08324719 ! digestion GO:0007586 112 81 2,000 0,01390383 0,08363155 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01390383 0,08342299 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 0,01436755 0,08599085 ! cholesterol metabolic process GO:0008203 136 82 2,000 0,01436755 0,08577747 ! response to drug GO:0042493 143 82 2,000 0,01436755 0,08556515 ! regulation of cyclase activity GO:0031279 159 82 2,000 0,01436755 0,08535388 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01473198 0,0873033 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01473198 0,0870888 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01473198 0,08687534 ! response to heat GO:0009408 50 30 1,000 0,01473198 0,08666293 ! regulation of lyase activity GO:0051339 160 83 2,000 0,01483996 0,08708524 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 0,01532109 0,08968989 ! collagen metabolic process GO:0032963 45 31 1,000 0,01568472 0,0915957 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01568472 0,09137391 GO:0055092|sterol homeostasis, ! peptide transport GO:0015833 55 31 1,000 0,01568472 0,0911532 ! response to inorganic substance GO:0010035 153 86 2,000 0,01630956 0,09455615 ! cholesterol transport GO:0030301 56 32 1,000 0,01666319 0,09637413 ! metanephros development GO:0001656 74 32 1,000 0,01666319 0,09614301 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01666319 0,09591301 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01666319 0,0956841 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01666319 0,09545628 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 0,01681693 0,09610815 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01733307 0,09882315 ! ceramide metabolic process GO:0006672 64 33 1,000 0,01766705 0,10048919 ! sterol transport GO:0015918 57 33 1,000 0,01766705 0,10025218 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01766705 0,1000163 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01766705 0,09978152 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 0,01839172 0,10363109 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01839172 0,10338897 ! glial cell differentiation GO:0010001 63 34 1,000 0,01869595 0,10485422 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01869595 0,10461037 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01869595 0,10436765 ! placenta development GO:0001890 53 34 1,000 0,01869595 0,10412606 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01869595 0,10388559 ! sterol metabolic process GO:0016125 152 91 2,000 0,01893424 0,10496726 ! cofactor biosynthetic process GO:0051188 139 91 2,000 0,01893424 0,10472596 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01974955 0,10898488 ! telencephalon development GO:0021537 68 35 1,000 0,01974955 0,10873549 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01974955 0,10848723 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01974955 0,10824011 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 0,02004573 0,10961371 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,02004573 0,10936515 ! transcription initiation GO:0006352 153 94 2,000 0,02061471 0,1122149 ! sphingoid metabolic process GO:0046519 70 36 1,000 0,02082749 0,11311728 ! hormone biosynthetic process GO:0042446 57 36 1,000 0,02082749 0,11286251 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,02082749 0,11260888 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02082749 0,1123564 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 0,02119251 0,11406973 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,02119251 0,11381511 ! meiosis I GO:0007127 65 37 1,000 0,02192946 0,11751065 ! tissue remodeling GO:0048771 76 37 1,000 0,02192946 0,11724951 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02192946 0,11698954 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,02237459 0,11910015 ! hormone metabolic process GO:0042445 157 97 2,000 0,02237459 0,11883724 ! interphase GO:0051325 213 98 2,000 0,02297888 0,12177794 ! lipid homeostasis GO:0055088 67 38 1,000 0,02305511 0,12191338 ! glucan metabolic process GO:0044042 62 38 1,000 0,02305511 0,12164603 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,02420411 0,12742906 ! learning GO:0007612 77 39 1,000 0,02420411 0,12715083 ! cytokinesis GO:0000910 72 40 1,000 0,02537613 0,13301735 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02657085 0,13897708 ! gliogenesis GO:0042063 88 41 1,000 0,02657085 0,13867562 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02657085 0,13837545 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02657085 0,13807659 ! polyol metabolic process GO:0019751 66 41 1,000 0,02657085 0,13777901 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02778794 0,1437802 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02778794 0,14347165 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,0290271 0,14954859 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,0290271 0,14922905 ! phagocytosis GO:0006909 90 43 1,000 0,0290271 0,14891086 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,0290271 0,14859403 ! activation of adenylate cyclase activity GO:0007190 91 44 1,000 0,03028799 0,15471955 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,03028799 0,15439175 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0305025 0,15515648 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0305025 0,15482914 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0305025 0,15450319 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0305025 0,1541786 ! neuron fate determination GO:0048664 7 5 0,000 0,0305025 0,15385538 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0305025 0,1535335 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0305025 0,15321297 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0305025 0,15289378 ! polyol transport GO:0015791 12 5 0,000 0,0305025 0,15257591 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0305025 0,15225936 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0305025 0,15194413 ! response to superoxide GO:0000303 10 5 0,000 0,0305025 0,15163019 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0305025 0,15131755 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0305025 0,1510062 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0305025 0,15069613 ! female meiosis GO:0007143 7 5 0,000 0,0305025 0,15038732 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0305025 0,15007978 ! cobalt ion transport GO:0006824 11 5 0,000 0,0305025 0,1497735 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0305025 0,14946846 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0305025 0,14916466 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0305025 0,1488621 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0305025 0,14856076 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0305025 0,14826063 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0305025 0,14796172 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0305025 0,14766401 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0305025 0,1473675 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0305025 0,14707217 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0305025 0,14677803 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0305025 0,14648506 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0305025 0,14619325 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,0305025 0,14590261 ! negative chemotaxis GO:0050919 14 5 0,000 0,0305025 0,14561312 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0305025 0,14532478 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0305025 0,14503758 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0305025 0,14475151 ! behavioral response to pain GO:0048266 9 5 0,000 0,0305025 0,14446656 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0305025 0,14418274 ! Notch receptor processing GO:0007220 8 5 0,000 0,0305025 0,14390003 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0305025 0,14361842 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0305025 0,14333792 ! micturition GO:0060073 9 5 0,000 0,0305025 0,14305851 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0305025 0,14278018 ! copulation GO:0007620 9 5 0,000 0,0305025 0,14250294 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0305025 0,14222677 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0305025 0,14195167 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0305025 0,14167763 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0305025 0,14140465 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0305025 0,14113272 ! grooming behavior GO:0007625 6 5 0,000 0,0305025 0,14086183 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0305025 0,14059198 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0305025 0,14032316 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0305025 0,14005537 ! response to protozoan GO:0001562 10 5 0,000 0,0305025 0,1397886 ! lymph vessel development GO:0001945 10 5 0,000 0,0305025 0,13952284 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0305025 0,13925809 ! endochondral ossification GO:0001958 16 5 0,000 0,0305025 0,13899434 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0305025 0,1387316 ! parathyroid gland development GO:0060017 13 5 0,000 0,0305025 0,13846984 ! anagen GO:0042640 6 5 0,000 0,0305025 0,13820907 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0305025 0,13794927 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0305025 0,13769046 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0305025 0,13743261 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0305025 0,13717573 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0305025 0,1369198 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0305025 0,13666483 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0305025 0,13641081 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0305025 0,13615773 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0305025 0,13590558 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0305025 0,13565437 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0305025 0,13540408 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0305025 0,13515472 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0305025 0,13490628 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0305025 0,13465874 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0305025 0,13441211 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0305025 0,13416639 ! histidine catabolic process GO:0006548 6 5 0,000 0,0305025 0,13392156 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0305025 0,13367762 ! microvillus organization GO:0032528 7 5 0,000 0,0305025 0,13343457 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,0305025 0,1331924 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0305025 0,13295111 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0305025 0,13271069 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0305025 0,13247114 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0305025 0,13223246 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0305025 0,13199463 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0305025 0,13175766 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0305025 0,13152153 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0305025 0,13128625 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0305025 0,13105181 ! muscle cell migration GO:0014812 8 5 0,000 0,0305025 0,13081821 ! mitochondrial fission GO:0000266 8 5 0,000 0,0305025 0,13058543 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0305025 0,13035349 ! mRNA transcription GO:0009299 9 5 0,000 0,0305025 0,13012237 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0305025 0,12989206 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0305025 0,12966257 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0305025 0,12943389 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0305025 0,12920601 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0305025 0,12897893 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0305025 0,12875266 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0305025 0,12852717 ! response to food GO:0032094 6 5 0,000 0,0305025 0,12830247 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0305025 0,12807856 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0305025 0,12785542 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0305025 0,12763307 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0305025 0,12741148 ! forebrain neuron development GO:0021884 13 5 0,000 0,0305025 0,12719067 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0305025 0,12697061 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0305025 0,12675132 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0305025 0,12653278 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0305025 0,126315 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0305025 0,12609796 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0305025 0,12588167 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0305025 0,12566612 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0305025 0,12545131 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0305025 0,12523723 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0305025 0,12502387 ! basic amino acid transport GO:0015802 11 5 0,000 0,0305025 0,12481125 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0305025 0,12459934 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0305025 0,12438816 ! depyrimidination GO:0045008 10 5 0,000 0,0305025 0,12417769 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0305025 0,12396793 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0305025 0,12375888 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0305025 0,12355053 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0305025 0,12334288 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0305025 0,12313593 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0305025 0,12292967 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0305025 0,1227241 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0305025 0,12251922 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0305025 0,12231502 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0305025 0,1221115 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0305025 0,12190866 ! response to arsenic GO:0046685 10 5 0,000 0,0305025 0,12170649 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0305025 0,12150499 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0305025 0,12130416 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0305025 0,12110398 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0305025 0,12090447 ! response to cadmium ion GO:0046686 7 5 0,000 0,0305025 0,12070561 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0305025 0,12050741 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0305025 0,12030986 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0305025 0,12011295 ! decidualization GO:0046697 11 5 0,000 0,0305025 0,11991669 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0305025 0,11972107 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0305025 0,11952608 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0305025 0,11933173 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0305025 0,11913801 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0305025 0,11894492 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0305025 0,11875245 ! neural tube patterning GO:0021532 7 5 0,000 0,0305025 0,1185606 ! embryonic cleavage GO:0040016 6 5 0,000 0,0305025 0,11836938 ! peroxisome fission GO:0016559 5 5 0,000 0,0305025 0,11817877 ! histone demethylation GO:0016577 10 5 0,000 0,0305025 0,11798877 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0305025 0,11779938 ! mitotic recombination GO:0006312 9 5 0,000 0,0305025 0,1176106 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0305025 0,11742242 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0305025 0,11723485 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0305025 0,11704787 ! enteric nervous system development GO:0048484 8 5 0,000 0,0305025 0,11686149 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0305025 0,1166757 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0305025 0,1164905 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0305025 0,11630589 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0305025 0,11612186 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0305025 0,11593841 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0305025 0,11575554 ! plasminogen activation GO:0031639 5 5 0,000 0,0305025 0,11557325 ! B cell homeostasis GO:0001782 13 5 0,000 0,0305025 0,11539153 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0305025 0,11521038 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0305025 0,1150298 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0305025 0,11484979 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0305025 0,11467033 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0305025 0,11449144 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0305025 0,11431311 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0305025 0,11413532 ! response to redox state GO:0051775 5 5 0,000 0,0305025 0,1139581 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0305025 0,11378142 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0305025 0,11360528 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0305025 0,1134297 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0305025 0,11325465 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0305025 0,11308014 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0305025 0,11290618 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0305025 0,11273274 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0305025 0,11255984 ! striatum development GO:0021756 9 5 0,000 0,0305025 0,11238746 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0305025 0,11221562 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0305025 0,1120443 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0305025 0,1118735 ! glial cell migration GO:0008347 11 5 0,000 0,0305025 0,11170322 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0305025 0,11153346 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0305025 0,11136421 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0305025 0,11119548 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0305025 0,11102725 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0305025 0,11085954 ! neuroprotection GO:0043526 6 5 0,000 0,0305025 0,11069233 ! neural plate development GO:0001840 8 5 0,000 0,0305025 0,11052562 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0305025 0,11035942 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0305025 0,11019371 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0305025 0,11002851 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0305025 0,10986379 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0305025 0,10969957 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0305025 0,10953584 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0305025 0,1093726 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0305025 0,10920984 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0305025 0,10904757 ! spindle assembly GO:0051225 6 5 0,000 0,0305025 0,10888578 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0305025 0,10872447 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0305025 0,10856363 ! drug metabolic process GO:0017144 6 5 0,000 0,0305025 0,10840327 ! stem cell division GO:0017145 11 5 0,000 0,0305025 0,10824338 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0305025 0,10808397 ! organ regeneration GO:0031100 7 5 0,000 0,0305025 0,10792502 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0305025 0,10776654 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0305025 0,10760852 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0305025 0,10745097 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03157031 0,11104997 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03157031 0,11088785 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,03287376 0,11529776 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03419801 0,11976771 ! protein homooligomerization GO:0051260 76 47 1,000 0,03419801 0,11959363 ! cellular component disassembly GO:0022411 86 48 1,000 0,03554278 0,124116 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03554278 0,12393612 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,03554278 0,12375676 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03649103 0,12687487 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03649103 0,12669179 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03649103 0,12650924 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03649103 0,12632721 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03649103 0,1261457 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03649103 0,12596472 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03649103 0,12578426 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03649103 0,12560431 ! sleep GO:0030431 13 6 0,000 0,03649103 0,12542487 ! response to oxygen radical GO:0000305 11 6 0,000 0,03649103 0,12524595 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03649103 0,12506754 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03649103 0,12488963 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03649103 0,12471223 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03649103 0,12453533 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03649103 0,12435894 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03649103 0,12418304 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03649103 0,12400764 ! forebrain regionalization GO:0021871 8 6 0,000 0,03649103 0,12383274 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03649103 0,12365832 ! male meiosis GO:0007140 7 6 0,000 0,03649103 0,1234844 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03649103 0,12331097 ! response to zinc ion GO:0010043 9 6 0,000 0,03649103 0,12313802 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03649103 0,12296556 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03649103 0,12279358 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03649103 0,12262208 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03649103 0,12245106 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03649103 0,12228052 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03649103 0,12211045 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03649103 0,12194085 ! protein refolding GO:0042026 15 6 0,000 0,03649103 0,12177172 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03649103 0,12160306 ! opsonization GO:0008228 8 6 0,000 0,03649103 0,12143487 ! mating behavior GO:0007617 7 6 0,000 0,03649103 0,12126714 ! neuron remodeling GO:0016322 15 6 0,000 0,03649103 0,12109988 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03649103 0,12093307 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03649103 0,12076673 ! equilibrioception GO:0050957 14 6 0,000 0,03649103 0,12060084 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03649103 0,12043541 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03649103 0,12027043 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03649103 0,1201059 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03649103 0,11994182 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03649103 0,11977819 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03649103 0,119615 ! toxin metabolic process GO:0009404 11 6 0,000 0,03649103 0,11945226 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03649103 0,11928996 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03649103 0,1191281 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03649103 0,11896668 ! nuclear migration GO:0007097 12 6 0,000 0,03649103 0,1188057 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03649103 0,11864515 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03649103 0,11848503 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03649103 0,11832535 ! thymic T cell selection GO:0045061 12 6 0,000 0,03649103 0,1181661 ! protein lipoylation GO:0009249 10 6 0,000 0,03649103 0,11800727 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03649103 0,11784887 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03649103 0,1176909 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03649103 0,11753335 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03649103 0,11737622 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03649103 0,11721951 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03649103 0,11706321 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03649103 0,11690734 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03649103 0,11675188 ! hyperosmotic response GO:0006972 9 6 0,000 0,03649103 0,11659683 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03649103 0,11644219 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03649103 0,11628796 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03649103 0,11613414 ! urea metabolic process GO:0019627 7 6 0,000 0,03649103 0,11598073 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03649103 0,11582772 ! neutrophil activation GO:0042119 8 6 0,000 0,03649103 0,11567511 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03649103 0,11552291 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03649103 0,1153711 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03649103 0,1152197 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03649103 0,11506869 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03649103 0,11491808 ! neuron apoptosis GO:0051402 9 6 0,000 0,03649103 0,11476786 ! nucleoside salvage GO:0043174 9 6 0,000 0,03649103 0,11461803 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03649103 0,11446859 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03649103 0,11431955 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03649103 0,11417089 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03649103 0,11402261 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03649103 0,11387472 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03649103 0,11372722 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03649103 0,11358009 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03649103 0,11343335 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03649103 0,11328698 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03649103 0,11314099 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03649103 0,11299538 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03649103 0,11285014 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03649103 0,11270528 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03649103 0,11256078 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03649103 0,11241666 ! monocyte differentiation GO:0030224 12 6 0,000 0,03649103 0,1122729 ! neural nucleus development GO:0048857 14 6 0,000 0,03649103 0,11212952 ! response to UV-C GO:0010225 11 6 0,000 0,03649103 0,11198649 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03649103 0,11184384 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03649103 0,11170154 ! interaction with symbiont GO:0051702 13 6 0,000 0,03649103 0,11155961 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03649103 0,11141803 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03649103 0,11127682 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03649103 0,11113596 ! response to copper ion GO:0046688 10 6 0,000 0,03649103 0,11099546 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03649103 0,11085532 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03649103 0,11071552 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03649103 0,11057608 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03649103 0,11043699 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03649103 0,11029825 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03649103 0,11015986 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03649103 0,11002182 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03649103 0,10988412 ! hair follicle maturation GO:0048820 7 6 0,000 0,03649103 0,10974676 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03649103 0,10960975 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03649103 0,10947308 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03649103 0,10933675 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03649103 0,10920076 ! subpallium development GO:0021544 10 6 0,000 0,03649103 0,10906511 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03649103 0,10892979 ! histone ubiquitination GO:0016574 8 6 0,000 0,03649103 0,10879481 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03649103 0,10866016 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03649103 0,10852585 ! G2 phase GO:0051319 16 6 0,000 0,03649103 0,10839187 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03649103 0,10825821 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03649103 0,10812489 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03649103 0,1079919 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03649103 0,10785923 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03649103 0,10772688 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03649103 0,10759487 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03649103 0,10746317 ! receptor internalization GO:0031623 10 6 0,000 0,03649103 0,1073318 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03649103 0,10720075 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03649103 0,10707001 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03649103 0,1069396 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03649103 0,1068095 ! protein deubiquitination GO:0016579 14 6 0,000 0,03649103 0,10667972 ! protein destabilization GO:0031648 9 6 0,000 0,03649103 0,10655026 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03649103 0,1064211 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03649103 0,10629226 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03649103 0,10616374 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03649103 0,10603552 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03649103 0,10590761 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03649103 0,10578001 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03649103 0,10565272 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03649103 0,10552573 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03649103 0,10539905 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03649103 0,10527267 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03649103 0,1051466 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03649103 0,10502083 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03649103 0,10489535 ! catecholamine transport GO:0051937 9 6 0,000 0,03649103 0,10477018 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03649103 0,1046453 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03649103 0,10452073 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03649103 0,10439645 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03649103 0,10427246 ! maternal placenta development GO:0001893 12 6 0,000 0,03649103 0,10414877 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03649103 0,10402537 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03649103 0,10390226 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03649103 0,10377945 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03649103 0,10365692 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03649103 0,10353468 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03649103 0,10341273 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03690775 0,10447064 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03690775 0,10434788 ! endocrine system development GO:0035270 104 49 1,000 0,03690775 0,10422541 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,03690775 0,10410322 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03690775 0,10398132 ! neuromuscular process GO:0050905 99 50 1,000 0,03829263 0,10775681 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03829263 0,10763093 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03829263 0,10750534 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,03969713 0,11131852 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,03969713 0,11118893 ! positive regulation of growth GO:0045927 90 52 1,000 0,04112095 0,11504303 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,04112095 0,11490941 ! synapse organization GO:0050808 85 52 1,000 0,04112095 0,11477611 ! tRNA transcription GO:0009304 14 7 0,000 0,04244276 0,11832825 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04244276 0,1181913 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04244276 0,11805466 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04244276 0,11791834 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04244276 0,11778233 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04244276 0,11764664 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04244276 0,11751126 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04244276 0,11737619 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04244276 0,11724143 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04244276 0,11710698 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04244276 0,11697283 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04244276 0,116839 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04244276 0,11670547 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04244276 0,11657224 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04244276 0,11643932 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04244276 0,1163067 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04244276 0,11617438 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04244276 0,11604237 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04244276 0,11591065 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04244276 0,11577923 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04244276 0,11564811 ! glycolipid transport GO:0046836 10 7 0,000 0,04244276 0,11551729 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04244276 0,11538676 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04244276 0,11525653 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04244276 0,11512659 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04244276 0,11499694 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04244276 0,11486759 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04244276 0,11473852 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04244276 0,11460975 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04244276 0,11448126 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04244276 0,11435306 ! pericardium development GO:0060039 14 7 0,000 0,04244276 0,11422515 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04244276 0,11409752 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04244276 0,11397018 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04244276 0,11384313 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04244276 0,11371635 ! lipoprotein transport GO:0042953 14 7 0,000 0,04244276 0,11358986 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04244276 0,11346365 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04244276 0,11333772 ! rhythmic behavior GO:0007622 15 7 0,000 0,04244276 0,11321207 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04244276 0,11308669 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04244276 0,1129616 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04244276 0,11283678 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04244276 0,11271223 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04244276 0,11258796 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04244276 0,11246397 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04244276 0,11234025 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04244276 0,11221679 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04244276 0,11209361 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04244276 0,11197071 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04244276 0,11184806 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04244276 0,11172569 ! spinal cord patterning GO:0021511 13 7 0,000 0,04244276 0,11160359 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04244276 0,11148175 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04244276 0,11136018 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04244276 0,11123887 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04244276 0,11111783 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04244276 0,11099705 ! ovulation GO:0030728 9 7 0,000 0,04244276 0,11087653 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04244276 0,11075627 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04244276 0,11063628 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,04244276 0,11051654 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04244276 0,11039706 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04244276 0,11027784 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04244276 0,11015888 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04244276 0,11004018 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04244276 0,10992173 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04244276 0,10980353 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04244276 0,10968559 ! galactose metabolic process GO:0006012 13 7 0,000 0,04244276 0,1095679 ! vesicle fusion GO:0006906 17 7 0,000 0,04244276 0,10945046 ! response to dietary excess GO:0002021 8 7 0,000 0,04244276 0,10933328 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04244276 0,10921635 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04244276 0,10909966 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04244276 0,10898323 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04244276 0,10886704 ! organ growth GO:0035265 15 7 0,000 0,04244276 0,1087511 ! purine salvage GO:0043101 10 7 0,000 0,04244276 0,10863541 ! nucleoside transport GO:0015858 8 7 0,000 0,04244276 0,10851996 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04244276 0,10840476 ! parturition GO:0007567 14 7 0,000 0,04244276 0,1082898 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04244276 0,10817509 ! rRNA modification GO:0000154 14 7 0,000 0,04244276 0,10806062 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04244276 0,10794639 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04244276 0,1078324 ! macrophage differentiation GO:0030225 11 7 0,000 0,04244276 0,10771865 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04244276 0,10760515 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04244276 0,10749188 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04244276 0,10737885 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04244276 0,10726605 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04244276 0,1071535 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04244276 0,10704118 ! fibrinolysis GO:0042730 10 7 0,000 0,04244276 0,10692909 ! eating behavior GO:0042755 7 7 0,000 0,04244276 0,10681724 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04244276 0,10670563 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04244276 0,10659424 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04244276 0,10648309 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04244276 0,10637217 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04244276 0,10626148 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04244276 0,10615102 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04244276 0,10604079 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04244276 0,10593079 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04244276 0,10582102 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04244276 0,10571147 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04244276 0,10560215 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04244276 0,10549306 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04244276 0,10538419 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04244276 0,10527555 ! regulation of meiosis GO:0040020 12 7 0,000 0,04244276 0,10516713 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04244276 0,10505893 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04244276 0,10495096 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04244276 0,10484321 GO:0002714|positive regulation of B cell mediated immunity, ! oxygen homeostasis GO:0032364 12 7 0,000 0,04244276 0,10473568 ! transcription termination GO:0006353 13 7 0,000 0,04244276 0,10462836 ! response to tumor cell GO:0002347 13 7 0,000 0,04244276 0,10452127 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04244276 0,1044144 ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04244276 0,10430775 ! axonal fasciculation GO:0007413 18 7 0,000 0,04244276 0,10420131 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04244276 0,10409509 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04244276 0,10398909 ! diuresis GO:0030146 12 7 0,000 0,04244276 0,1038833 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04244276 0,10377773 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04244276 0,10367237 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04244276 0,10356722 ! antibiotic transport GO:0042891 9 7 0,000 0,04244276 0,10346229 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04244276 0,10335757 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04244276 0,10325307 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04244276 0,10314877 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04244276 0,10304469 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04244276 0,10294081 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04244276 0,10283714 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04244276 0,10273369 ! lymph node development GO:0048535 10 7 0,000 0,04244276 0,10263044 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04244276 0,10252739 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04244276 0,10242456 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04244276 0,10232193 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04244276 0,1022195 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04244276 0,10211728 ! adult feeding behavior GO:0008343 9 7 0,000 0,04244276 0,10201527 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04244276 0,10191346 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04244276 0,10181185 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04244276 0,10171044 ! muscle adaptation GO:0043500 14 7 0,000 0,04244276 0,10160924 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04244276 0,10150823 ! retina homeostasis GO:0001895 12 7 0,000 0,04244276 0,10140743 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04244276 0,10130683 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04244276 0,10120643 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04244276 0,10110622 ! protein prenylation GO:0018342 18 7 0,000 0,04244276 0,10100621 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04244276 0,10090641 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04244276 0,10080679 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04244276 0,10070738 ! cell maturation GO:0048469 100 53 1,000 0,0425638 0,10089508 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,0425638 0,10079578 ! response to UV GO:0009411 104 53 1,000 0,0425638 0,10069667 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,0440254 0,10405218 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,0440254 0,10395007 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,04550547 0,10733936 ! gastrulation GO:0007369 112 55 1,000 0,04550547 0,10723423 ! heart morphogenesis GO:0003007 97 55 1,000 0,04550547 0,10712931 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04700371 0,11054832 ! glycosaminoglycan metabolic process GO:0030203 91 56 1,000 0,04700371 0,11044036 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04700371 0,11033261 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04700371 0,11022508 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04835793 0,11329033 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04835793 0,11318013 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04835793 0,11307014 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04835793 0,11296036 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04835793 0,1128508 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04835793 0,11274145 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04835793 0,11263231 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04835793 0,11252338 ! meiotic prophase I GO:0007128 13 8 0,000 0,04835793 0,11241466 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04835793 0,11230615 ! UTP metabolic process GO:0046051 8 8 0,000 0,04835793 0,11219785 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04835793 0,11208976 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04835793 0,11198188 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04835793 0,1118742 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04835793 0,11176674 ! succinate metabolic process GO:0006105 14 8 0,000 0,04835793 0,11165947 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04835793 0,11155242 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04835793 0,11144557 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04835793 0,11133892 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04835793 0,11123248 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04835793 0,11112624 ! reflex GO:0060004 16 8 0,000 0,04835793 0,1110202 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04835793 0,11091437 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04835793 0,11080874 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04835793 0,1107033 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04835793 0,11059807 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04835793 0,11049304 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04835793 0,11038821 ! pigment granule organization GO:0048753 16 8 0,000 0,04835793 0,11028358 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04835793 0,11017914 ! histidine metabolic process GO:0006547 16 8 0,000 0,04835793 0,1100749 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04835793 0,10997086 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04835793 0,10986702 ! glycine catabolic process GO:0006546 13 8 0,000 0,04835793 0,10976337 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04835793 0,10965992 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04835793 0,10955666 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04835793 0,1094536 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04835793 0,10935073 ! melanin metabolic process GO:0006582 15 8 0,000 0,04835793 0,10924805 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04835793 0,10914557 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04835793 0,10904327 ! macrophage activation GO:0042116 12 8 0,000 0,04835793 0,10894117 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04835793 0,10883926 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04835793 0,10873754 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04835793 0,10863602 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04835793 0,10853468 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04835793 0,10843353 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04835793 0,10833256 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04835793 0,10823179 ! osteoblast development GO:0002076 16 8 0,000 0,04835793 0,1081312 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04835793 0,1080308 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04835793 0,10793059 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04835793 0,10783056 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04835793 0,10773072 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04835793 0,10763106 ! response to UV-B GO:0010224 16 8 0,000 0,04835793 0,10753158 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04835793 0,10743229 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04835793 0,10733318 ! intermediate filament organization GO:0045109 12 8 0,000 0,04835793 0,10723426 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04835793 0,10713552 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04835793 0,10703696 ! cellular extravasation GO:0045123 12 8 0,000 0,04835793 0,10693858 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04835793 0,10684038 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04835793 0,10674236 ! response to antibiotic GO:0046677 11 8 0,000 0,04835793 0,10664452 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04835793 0,10654686 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04835793 0,10644938 ! DNA topological change GO:0006265 12 8 0,000 0,04835793 0,10635208 ! response to tropane GO:0014073 15 8 0,000 0,04835793 0,10625495 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04835793 0,106158 ! melanosome transport GO:0032402 13 8 0,000 0,04835793 0,10606123 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04835793 0,10596464 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04835793 0,10586822 ! mast cell activation GO:0045576 14 8 0,000 0,04835793 0,10577197 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04835793 0,10567591 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04835793 0,10558001 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04835793 0,10548429 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04835793 0,10538874 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04835793 0,10529337 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04835793 0,10519817 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04835793 0,10510314 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04835793 0,10500828 ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04835793 0,10491359 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04835793 0,10481907 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04835793 0,10472473 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04835793 0,10463055 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04835793 0,10453654 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04835793 0,1044427 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04835793 0,10434903 ! hormone catabolic process GO:0042447 17 8 0,000 0,04835793 0,10425553 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04835793 0,1041622 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04835793 0,10406903 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04835793 0,10397603 ! ATP catabolic process GO:0006200 11 8 0,000 0,04835793 0,10388319 ! blastocyst growth GO:0001832 19 8 0,000 0,04835793 0,10379052 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04835793 0,10369801 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04835793 0,10360567 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04835793 0,1035135 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04835793 0,10342149 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04835793 0,10332964 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04835793 0,10323795 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04835793 0,10314643 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04835793 0,10305507 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04835793 0,10296387 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04835793 0,10287283 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04835793 0,10278195 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04835793 0,10269124 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04835793 0,10260068 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04835793 0,10251028 ! muscle fiber development GO:0048747 112 57 1,000 0,04851986 0,10276301 ! lipid modification GO:0030258 97 57 1,000 0,04851986 0,10267263 ! regulation of endocytosis GO:0030100 91 58 1,000 0,05005364 0,10582517 ! adult behavior GO:0030534 99 58 1,000 0,05005364 0,10573226 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,05160477 0,10891322 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,05160477 0,10881776 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05317298 0,11202644 ! camera-type eye development GO:0043010 116 60 1,000 0,05317298 0,11192843 ! kidney development GO:0001822 122 60 1,000 0,05317298 0,11183059 ! axon extension GO:0048675 15 9 0,000 0,05423675 0,11396822 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05423675 0,11386877 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05423675 0,1137695 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05423675 0,1136704 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05423675 0,11357147 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05423675 0,11347271 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05423675 0,11337412 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05423675 0,11327571 ! phosphate transport GO:0006817 19 9 0,000 0,05423675 0,11317746 ! reproductive behavior GO:0019098 19 9 0,000 0,05423675 0,11307939 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05423675 0,11298149 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05423675 0,11288375 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05423675 0,11278619 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05423675 0,11268879 ! GTP metabolic process GO:0046039 9 9 0,000 0,05423675 0,11259156 ! RNA methylation GO:0001510 15 9 0,000 0,05423675 0,1124945 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05423675 0,1123976 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05423675 0,11230087 ! regulation of histone modification GO:0031056 12 9 0,000 0,05423675 0,11220431 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05423675 0,11210792 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05423675 0,11201169 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05423675 0,11191562 ! chemosensory behavior GO:0007635 20 9 0,000 0,05423675 0,11181972 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05423675 0,11172399 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05423675 0,11162841 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05423675 0,11153301 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05423675 0,11143776 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05423675 0,11134268 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05423675 0,11124775 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05423675 0,11115299 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05423675 0,1110584 ! protein targeting to ER GO:0045047 22 9 0,000 0,05423675 0,11096396 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05423675 0,11086968 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05423675 0,11077557 ! T cell selection GO:0045058 23 9 0,000 0,05423675 0,11068161 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05423675 0,11058781 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05423675 0,11049417 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05423675 0,11040069 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05423675 0,11030737 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05423675 0,1102142 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05423675 0,1101212 ! mannose metabolic process GO:0006013 13 9 0,000 0,05423675 0,11002834 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05423675 0,10993565 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05423675 0,10984311 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05423675 0,10975073 ! receptor clustering GO:0043113 18 9 0,000 0,05423675 0,1096585 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05423675 0,10956643 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05423675 0,10947451 ! ruffle organization GO:0031529 15 9 0,000 0,05423675 0,10938275 ! retinol metabolic process GO:0042572 18 9 0,000 0,05423675 0,10929114 ! behavioral fear response GO:0001662 22 9 0,000 0,05423675 0,10919968 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05423675 0,10910837 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05423675 0,10901722 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05423675 0,10892622 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05423675 0,10883538 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05423675 0,10874468 ! segment specification GO:0007379 13 9 0,000 0,05423675 0,10865413 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05423675 0,10856374 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05423675 0,1084735 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05423675 0,1083834 ! response to amine stimulus GO:0014075 13 9 0,000 0,05423675 0,10829346 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05423675 0,10820366 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05423675 0,10811401 ! erythrocyte development GO:0048821 15 9 0,000 0,05423675 0,10802452 ! gas homeostasis GO:0033483 16 9 0,000 0,05423675 0,10793517 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05423675 0,10784596 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05423675 0,10775691 ! renal water homeostasis GO:0003091 14 9 0,000 0,05423675 0,107668 ! postreplication repair GO:0006301 22 9 0,000 0,05423675 0,10757924 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05423675 0,10749062 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05423675 0,10740215 ! icosanoid secretion GO:0032309 15 9 0,000 0,05423675 0,10731383 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05423675 0,10722565 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05423675 0,10713762 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05423675 0,10704973 ! regulation of cell division GO:0051302 15 9 0,000 0,05423675 0,10696198 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05423675 0,10687438 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05423675 0,10678692 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05423675 0,1066996 ! sterol catabolic process GO:0016127 11 9 0,000 0,05423675 0,10661243 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05423675 0,1065254 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05423675 0,10643851 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05423675 0,10635177 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05423675 0,10626516 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05423675 0,10617869 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05423675 0,10609237 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05423675 0,10600619 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05423675 0,10592014 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05423675 0,10583424 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05423675 0,10574847 ! purine base metabolic process GO:0006144 21 9 0,000 0,05423675 0,10566285 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05423675 0,10557736 ! pigment granule transport GO:0051904 17 9 0,000 0,05423675 0,10549201 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05423675 0,1054068 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05423675 0,10532172 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05423675 0,10523679 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05423675 0,10515199 ! mitochondrion localization GO:0051646 15 9 0,000 0,05423675 0,10506732 ! sphingolipid metabolic process GO:0006665 107 61 1,000 0,05475801 0,10599178 ! viral reproductive process GO:0022415 126 62 1,000 0,0563596 0,10900418 ! detection of external stimulus GO:0009581 91 63 1,000 0,05797747 0,11204321 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06007945 0,11601216 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,06007945 0,11591912 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06007945 0,11582624 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06007945 0,11573351 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,06007945 0,11564092 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06007945 0,11554848 ! synapsis GO:0007129 13 10 0,000 0,06007945 0,11545619 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06007945 0,11536405 ! N-glycan processing GO:0006491 20 10 0,000 0,06007945 0,11527205 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06007945 0,1151802 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06007945 0,11508849 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06007945 0,11499694 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06007945 0,11490552 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06007945 0,11481426 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06007945 0,11472313 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06007945 0,11463216 ! androgen metabolic process GO:0008209 17 10 0,000 0,06007945 0,11454132 ! phospholipid efflux GO:0033700 16 10 0,000 0,06007945 0,11445063 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06007945 0,11436009 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06007945 0,11426968 ! pathogenesis GO:0009405 13 10 0,000 0,06007945 0,11417942 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06007945 0,1140893 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06007945 0,11399933 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06007945 0,11390949 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06007945 0,1138198 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06007945 0,11373025 ! endoderm development GO:0007492 16 10 0,000 0,06007945 0,11364084 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06007945 0,11355157 ! arginine catabolic process GO:0006527 13 10 0,000 0,06007945 0,11346244 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06007945 0,11337345 ! proline metabolic process GO:0006560 13 10 0,000 0,06007945 0,1132846 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06007945 0,11319589 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06007945 0,11310731 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06007945 0,11301888 ! V(D)J recombination GO:0033151 28 10 0,000 0,06007945 0,11293058 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06007945 0,11284243 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06007945 0,11275441 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06007945 0,11266652 ! B cell proliferation GO:0042100 18 10 0,000 0,06007945 0,11257878 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06007945 0,11249117 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06007945 0,11240369 ! multicellular organism growth GO:0035264 18 10 0,000 0,06007945 0,11231635 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06007945 0,11222915 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06007945 0,11214209 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06007945 0,11205515 ! macroautophagy GO:0016236 17 10 0,000 0,06007945 0,11196836 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06007945 0,11188169 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06007945 0,11179517 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06007945 0,11170877 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06007945 0,11162251 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06007945 0,11153638 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06007945 0,11145038 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06007945 0,11136452 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06007945 0,11127879 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06007945 0,11119319 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06007945 0,11110772 ! response to dsRNA GO:0043331 20 10 0,000 0,06007945 0,11102239 ! DNA ligation GO:0006266 19 10 0,000 0,06007945 0,11093718 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06007945 0,11085211 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06007945 0,11076716 ! melanosome localization GO:0032400 16 10 0,000 0,06007945 0,11068235 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06007945 0,11059767 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06007945 0,11051311 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06007945 0,11042868 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06007945 0,11034439 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06007945 0,11026022 ! mRNA cleavage GO:0006379 17 10 0,000 0,06007945 0,11017618 ! protein sumoylation GO:0016925 15 10 0,000 0,06007945 0,11009227 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06007945 0,11000848 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06007945 0,10992483 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06007945 0,1098413 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06007945 0,1097579 ! salivary gland development GO:0007431 27 10 0,000 0,06007945 0,10967462 ! prophase GO:0051324 15 10 0,000 0,06007945 0,10959147 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06007945 0,10950845 ! apical protein localization GO:0045176 15 10 0,000 0,06007945 0,10942555 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06007945 0,10934278 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06007945 0,10926013 ! midbrain development GO:0030901 13 10 0,000 0,06007945 0,1091776 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06007945 0,10909521 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06007945 0,10901293 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06007945 0,10893078 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06007945 0,10884876 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06007945 0,10876685 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06007945 0,10868507 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06007945 0,10860342 ! detection of calcium ion GO:0005513 23 10 0,000 0,06007945 0,10852188 ! oocyte development GO:0048599 17 10 0,000 0,06007945 0,10844047 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06007945 0,10835918 ! blastocyst formation GO:0001825 17 10 0,000 0,06007945 0,10827801 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06007945 0,10819697 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06007945 0,10811604 ! activation of innate immune response GO:0002218 12 10 0,000 0,06007945 0,10803524 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06007945 0,10795455 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06007945 0,10787399 ! response to nicotine GO:0035094 20 10 0,000 0,06007945 0,10779355 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06007945 0,10771323 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06007945 0,10763302 ! aminoglycan metabolic process GO:0006022 102 65 1,000 0,06126106 0,10966823 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,06126106 0,10958669 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,06126106 0,10950527 GO:0035113|embryonic appendage morphogenesis, ! developmental maturation GO:0021700 116 66 1,000 0,06292625 0,11239834 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,06460671 0,11531435 ! adaptive immune response GO:0002250 119 67 1,000 0,06460671 0,11522887 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06588624 0,11742393 ! respiratory burst GO:0045730 17 11 0,000 0,06588624 0,11733701 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06588624 0,11725022 ! neuron fate specification GO:0048665 17 11 0,000 0,06588624 0,11716356 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06588624 0,11707703 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06588624 0,11699063 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06588624 0,11690435 ! thyroid gland development GO:0030878 26 11 0,000 0,06588624 0,1168182 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06588624 0,11673218 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06588624 0,11664628 ! response to pain GO:0048265 24 11 0,000 0,06588624 0,11656052 ! T cell proliferation GO:0042098 26 11 0,000 0,06588624 0,11647487 ! bone resorption GO:0045453 16 11 0,000 0,06588624 0,11638935 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06588624 0,11630396 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06588624 0,1162187 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06588624 0,11613355 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06588624 0,11604854 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06588624 0,11596364 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06588624 0,11587887 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06588624 0,11579423 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06588624 0,11570971 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06588624 0,11562531 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06588624 0,11554104 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06588624 0,11545688 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06588624 0,11537285 ! UV protection GO:0009650 19 11 0,000 0,06588624 0,11528895 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06588624 0,11520516 ! temperature homeostasis GO:0001659 17 11 0,000 0,06588624 0,1151215 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06588624 0,11503795 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06588624 0,11495453 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06588624 0,11487123 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06588624 0,11478805 ! regulation of organ growth GO:0046620 13 11 0,000 0,06588624 0,11470499 ! pigment granule localization GO:0051875 20 11 0,000 0,06588624 0,11462205 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06588624 0,11453923 ! vasoconstriction GO:0042310 18 11 0,000 0,06588624 0,11445654 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06588624 0,11437395 ! embryonic axis specification GO:0000578 18 11 0,000 0,06588624 0,11429149 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06588624 0,11420915 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06588624 0,11412693 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06588624 0,11404482 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06588624 0,11396283 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06588624 0,11388096 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06588624 0,11379921 ! zymogen activation GO:0031638 15 11 0,000 0,06588624 0,11371758 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06588624 0,11363606 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06588624 0,11355466 ! nucleosome positioning GO:0016584 15 11 0,000 0,06588624 0,11347337 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06588624 0,1133922 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06588624 0,11331115 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06588624 0,11323021 ! acid secretion GO:0046717 18 11 0,000 0,06588624 0,11314939 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06588624 0,11306869 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06588624 0,1129881 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06588624 0,11290762 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06588624 0,11282726 ! oocyte differentiation GO:0009994 18 11 0,000 0,06588624 0,11274701 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06588624 0,11266688 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06588624 0,11258686 ! cholesterol efflux GO:0033344 19 11 0,000 0,06588624 0,11250696 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06588624 0,11242716 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06588624 0,11234748 ! germ cell migration GO:0008354 25 11 0,000 0,06588624 0,11226792 ! embryonic gut development GO:0048566 15 11 0,000 0,06588624 0,11218846 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06588624 0,11210912 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06588624 0,11202989 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06588624 0,11195078 ! defense response to fungus GO:0050832 13 11 0,000 0,06588624 0,11187177 ! developmental induction GO:0031128 19 11 0,000 0,06588624 0,11179288 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06588624 0,1117141 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06588624 0,11163542 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06588624 0,11155686 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06588624 0,11147841 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06588624 0,11140007 ! nucleus localization GO:0051647 19 11 0,000 0,06588624 0,11132184 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06588624 0,11124372 ! membrane lipid metabolic process GO:0006643 117 68 1,000 0,06630219 0,11186751 ! viral reproduction GO:0016032 134 68 1,000 0,06630219 0,11178911 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,06801243 0,11459238 ! appendage morphogenesis GO:0035107 135 70 1,000 0,0697372 0,11741617 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 1,000 0,07147625 0,12026004 ! appendage development GO:0048736 136 71 1,000 0,07147625 0,120176 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07147625 0,12009208 ! regulation of immune effector process GO:0002697 137 71 1,000 0,07147625 0,12000828 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07165736 0,12022845 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07165736 0,12014467 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07165736 0,120061 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07165736 0,11997745 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,07165736 0,11989402 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07165736 0,1198107 ! mating GO:0007618 17 12 0,000 0,07165736 0,1197275 ! protein complex disassembly GO:0043241 27 12 0,000 0,07165736 0,11964441 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07165736 0,11956144 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07165736 0,11947859 ! hippocampus development GO:0021766 26 12 0,000 0,07165736 0,11939585 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07165736 0,11931322 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07165736 0,11923071 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07165736 0,11914831 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07165736 0,11906602 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07165736 0,11898385 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07165736 0,11890179 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07165736 0,11881985 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07165736 0,11873802 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07165736 0,1186563 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07165736 0,11857469 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07165736 0,1184932 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07165736 0,11841181 ! forebrain cell migration GO:0021885 21 12 0,000 0,07165736 0,11833054 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07165736 0,11824938 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07165736 0,11816834 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07165736 0,1180874 ! entry into host cell GO:0030260 32 12 0,000 0,07165736 0,11800657 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07165736 0,11792586 ! monoamine transport GO:0015844 18 12 0,000 0,07165736 0,11784525 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07165736 0,11776476 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07165736 0,11768437 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07165736 0,11760409 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07165736 0,11752393 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07165736 0,11744387 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07165736 0,11736392 ! protein homotetramerization GO:0051289 21 12 0,000 0,07165736 0,11728408 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07165736 0,11720435 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07165736 0,11712473 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07165736 0,11704521 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07165736 0,11696581 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07165736 0,11688651 ! cranial nerve development GO:0021545 20 12 0,000 0,07165736 0,11680732 ! fucose catabolic process GO:0019317 22 12 0,000 0,07165736 0,11672823 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07165736 0,11664926 ! histone acetylation GO:0016573 26 12 0,000 0,07165736 0,11657039 ! histone methylation GO:0016571 26 12 0,000 0,07165736 0,11649162 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07165736 0,11641297 ! gland morphogenesis GO:0022612 29 12 0,000 0,07165736 0,11633441 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07165736 0,11625597 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,07165736 0,11617763 ! T cell homeostasis GO:0043029 25 12 0,000 0,07165736 0,11609939 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07165736 0,11602127 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07165736 0,11594324 ! spleen development GO:0048536 22 12 0,000 0,07165736 0,11586532 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07165736 0,11578751 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07165736 0,1157098 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07165736 0,11563219 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07165736 0,11555469 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07165736 0,11547729 ! response to cold GO:0009409 17 12 0,000 0,07165736 0,1154 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07165736 0,11532281 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07165736 0,11524572 ! regulation of caspase activity GO:0043281 122 72 1,000 0,07322934 0,11769526 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,07499624 0,12045458 ! axon guidance GO:0007411 139 73 1,000 0,07499624 0,12037422 ! neurotransmitter transport GO:0006836 123 74 1,000 0,07677671 0,12314984 ! meiosis GO:0007126 121 74 1,000 0,07677671 0,12306779 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 1,000 0,07677671 0,12298585 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,07677671 0,12290403 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07739301 0,12380823 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07739301 0,12372596 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07739301 0,12364381 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07739301 0,12356176 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07739301 0,12347982 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07739301 0,12339799 ! organelle fusion GO:0048284 32 13 0,000 0,07739301 0,12331627 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07739301 0,12323466 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07739301 0,12315316 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07739301 0,12307176 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07739301 0,12299047 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07739301 0,12290929 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07739301 0,12282822 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07739301 0,12274725 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07739301 0,12266639 ! methionine metabolic process GO:0006555 27 13 0,000 0,07739301 0,12258563 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07739301 0,12250498 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07739301 0,12242444 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07739301 0,122344 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07739301 0,12226367 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07739301 0,12218345 ! response to X-ray GO:0010165 25 13 0,000 0,07739301 0,12210333 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07739301 0,12202331 ! exocrine system development GO:0035272 32 13 0,000 0,07739301 0,1219434 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07739301 0,1218636 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07739301 0,12178389 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07739301 0,1217043 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07739301 0,1216248 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07739301 0,12154541 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07739301 0,12146613 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07739301 0,12138695 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07739301 0,12130787 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07739301 0,12122889 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07739301 0,12115002 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07739301 0,12107124 ! chromatin silencing GO:0006342 26 13 0,000 0,07739301 0,12099258 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07739301 0,12091401 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07739301 0,12083554 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07739301 0,12075718 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07739301 0,12067892 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07739301 0,12060076 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07739301 0,1205227 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07739301 0,12044474 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07739301 0,12036689 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07739301 0,12028913 ! embryonic placenta development GO:0001892 23 13 0,000 0,07739301 0,12021147 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07739301 0,12013392 ! insulin secretion GO:0030073 23 13 0,000 0,07739301 0,12005646 ! actin filament polymerization GO:0030041 24 13 0,000 0,07739301 0,11997911 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07739301 0,11990185 ! acrosome reaction GO:0007340 18 13 0,000 0,07739301 0,11982469 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,07857051 0,12156954 ! meiotic cell cycle GO:0051321 122 75 1,000 0,07857051 0,12149141 ! rhythmic process GO:0048511 128 75 1,000 0,07857051 0,12141338 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,08037741 0,12412584 ! regulation of catabolic process GO:0009894 161 76 1,000 0,08037741 0,12404622 ! rRNA transcription GO:0009303 25 14 0,000 0,08309341 0,1281556 ! lactation GO:0007595 26 14 0,000 0,08309341 0,12807351 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,08309341 0,12799151 ! reproductive cellular process GO:0048610 20 14 0,000 0,08309341 0,12790962 ! tRNA modification GO:0006400 20 14 0,000 0,08309341 0,12782784 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08309341 0,12774616 ! regulation of S phase GO:0033261 23 14 0,000 0,08309341 0,12766459 ! water transport GO:0006833 21 14 0,000 0,08309341 0,12758312 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08309341 0,12750175 ! non-recombinational repair GO:0000726 25 14 0,000 0,08309341 0,12742049 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08309341 0,12733933 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08309341 0,12725827 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08309341 0,12717732 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08309341 0,12709647 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08309341 0,12701572 ! palate development GO:0060021 31 14 0,000 0,08309341 0,12693507 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08309341 0,12685453 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08309341 0,12677409 ! arginine metabolic process GO:0006525 17 14 0,000 0,08309341 0,12669375 ! regulation of heart rate GO:0002027 24 14 0,000 0,08309341 0,12661352 ! organic alcohol transport GO:0015850 29 14 0,000 0,08309341 0,12653338 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,08309341 0,12645335 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08309341 0,12637341 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,08309341 0,12629358 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08309341 0,12621385 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08309341 0,12613422 ! L-amino acid transport GO:0015807 30 14 0,000 0,08309341 0,12605469 ! bone mineralization GO:0030282 17 14 0,000 0,08309341 0,12597526 ! stem cell development GO:0048864 43 14 0,000 0,08309341 0,12589593 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08309341 0,1258167 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08309341 0,12573757 ! cerebellum development GO:0021549 21 14 0,000 0,08309341 0,12565854 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08309341 0,12557961 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08309341 0,12550078 ! response to gamma radiation GO:0010332 28 14 0,000 0,08309341 0,12542205 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08309341 0,12534341 ! cofactor transport GO:0051181 26 14 0,000 0,08309341 0,12526488 ! NADP metabolic process GO:0006739 24 14 0,000 0,08309341 0,12518644 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08309341 0,1251081 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08309341 0,12502986 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08309341 0,12495171 ! oxygen transport GO:0015671 21 14 0,000 0,08309341 0,12487367 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08309341 0,12479572 ! male genitalia development GO:0030539 24 14 0,000 0,08309341 0,12471787 ! regulation of axon extension GO:0030516 37 14 0,000 0,08309341 0,12464011 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,08309341 0,12456246 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08309341 0,1244849 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,08402963 0,12580914 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,0858745 0,12849132 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,08773156 0,13118841 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08875878 0,132642 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08875878 0,13255967 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08875878 0,13247743 ! superoxide anion generation GO:0042554 20 15 0,000 0,08875878 0,1323953 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08875878 0,13231327 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08875878 0,13223134 ! copper ion transport GO:0006825 20 15 0,000 0,08875878 0,13214952 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08875878 0,13206779 ! sulfate transport GO:0008272 23 15 0,000 0,08875878 0,13198617 ! response to cAMP GO:0051591 22 15 0,000 0,08875878 0,13190465 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08875878 0,13182322 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08875878 0,1317419 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08875878 0,13166068 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08875878 0,13157956 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08875878 0,13149854 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08875878 0,13141761 ! pituitary gland development GO:0021983 29 15 0,000 0,08875878 0,13133679 ! vesicle coating GO:0006901 33 15 0,000 0,08875878 0,13125607 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08875878 0,13117544 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08875878 0,13109492 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08875878 0,13101449 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08875878 0,13093416 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08875878 0,13085393 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08875878 0,1307738 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08875878 0,13069377 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08875878 0,13061384 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08875878 0,130534 ! histone deacetylation GO:0016575 20 15 0,000 0,08875878 0,13045426 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08875878 0,13037462 ! tissue regeneration GO:0042246 26 15 0,000 0,08875878 0,13029507 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08875878 0,13021562 ! water homeostasis GO:0030104 27 15 0,000 0,08875878 0,13013627 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08875878 0,13005702 ! muscle maintenance GO:0046716 26 15 0,000 0,08875878 0,12997786 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08875878 0,1298988 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08875878 0,12981983 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08875878 0,12974096 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08875878 0,12966219 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08875878 0,12958351 ! cell killing GO:0001906 29 15 0,000 0,08875878 0,12950492 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08875878 0,12942644 ! detection of bacterium GO:0016045 18 15 0,000 0,08875878 0,12934804 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08875878 0,12926975 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08875878 0,12919154 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08875878 0,12911343 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08875878 0,12903542 ! peptide hormone processing GO:0016486 23 15 0,000 0,08875878 0,1289575 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09438933 0,13705536 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09438933 0,1369727 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09438933 0,13689013 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09438933 0,13680767 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09438933 0,1367253 ! bone remodeling GO:0046849 27 16 0,000 0,09438933 0,13664304 ! filopodium assembly GO:0046847 32 16 0,000 0,09438933 0,13656087 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09438933 0,1364788 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09438933 0,13639683 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09438933 0,13631496 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09438933 0,13623319 ! startle response GO:0001964 28 16 0,000 0,09438933 0,13615152 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09438933 0,13606994 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09438933 0,13598846 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09438933 0,13590708 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09438933 0,13582579 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09438933 0,13574461 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09438933 0,13566352 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09438933 0,13558252 ! response to osmotic stress GO:0006970 25 16 0,000 0,09438933 0,13550163 ! lysosomal transport GO:0007041 26 16 0,000 0,09438933 0,13542083 ! fructose metabolic process GO:0006000 25 16 0,000 0,09438933 0,13534012 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09438933 0,13525952 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09438933 0,13517901 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09438933 0,13509859 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09438933 0,13501827 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09438933 0,13493804 ! axon cargo transport GO:0008088 43 16 0,000 0,09438933 0,13485791 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09438933 0,13477788 ! DNA replication initiation GO:0006270 27 16 0,000 0,09438933 0,13469794 ! neuron recognition GO:0008038 35 16 0,000 0,09438933 0,1346181 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09438933 0,13453835 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09438933 0,13445869 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09438933 0,13437913 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09438933 0,13429966 ! biomineral formation GO:0031214 20 16 0,000 0,09438933 0,13422029 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09438933 0,13414101 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09438933 0,13406182 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09438933 0,13398273 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09438933 0,13390373 ! defense response to virus GO:0051607 37 16 0,000 0,09438933 0,13382483 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09719241 0,13771787 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,0991182 0,14036397 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09998528 0,14150857 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09998528 0,14142538 ! metencephalon development GO:0022037 30 17 0,000 0,09998528 0,14134229 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09998528 0,14125929 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09998528 0,14117639 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09998528 0,14109359 ! signal complex assembly GO:0007172 41 17 0,000 0,09998528 0,14101089 ! endothelial cell migration GO:0043542 28 17 0,000 0,09998528 0,14092828 ! inositol metabolic process GO:0006020 28 17 0,000 0,09998528 0,14084577 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09998528 0,14076336 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09998528 0,14068104 ! limbic system development GO:0021761 36 17 0,000 0,09998528 0,14059882 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09998528 0,14051669 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09998528 0,14043466 ! heart looping GO:0001947 30 17 0,000 0,09998528 0,14035273 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09998528 0,14027089 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09998528 0,14018915 ! myoblast differentiation GO:0045445 45 17 0,000 0,09998528 0,1401075 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09998528 0,14002595 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,09998528 0,13994449 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09998528 0,13986313 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09998528 0,13978186 ! glycine metabolic process GO:0006544 28 17 0,000 0,09998528 0,13970068 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09998528 0,1396196 ! NAD metabolic process GO:0019674 29 17 0,000 0,09998528 0,13953862 ! membrane budding GO:0006900 37 17 0,000 0,09998528 0,13945773 ! DNA integration GO:0015074 29 17 0,000 0,09998528 0,13937693 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,09998528 0,13929622 ! regulation of protein binding GO:0043393 33 17 0,000 0,09998528 0,13921561 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09998528 0,13913509 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09998528 0,13905467 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09998528 0,13897434 ! genitalia development GO:0048806 30 17 0,000 0,09998528 0,1388941 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,09998528 0,13881395 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09998528 0,1387339 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09998528 0,13865393 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09998528 0,13857406 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09998528 0,13849429 ! steroid catabolic process GO:0006706 31 17 0,000 0,09998528 0,1384146 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09998528 0,13833501 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09998528 0,1382555 ! gas transport GO:0015669 25 17 0,000 0,09998528 0,13817609 ! organic cation transport GO:0015695 31 17 0,000 0,09998528 0,13809677 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09998528 0,13801754 ! microspike assembly GO:0030035 36 17 0,000 0,09998528 0,1379384 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09998528 0,13785936 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,10495904 0,14463427 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10554683 0,145361 ! neuron maturation GO:0042551 42 18 0,000 0,10554683 0,14527784 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10554683 0,14519478 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10554683 0,14511181 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10554683 0,14502894 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10554683 0,14494616 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10554683 0,14486347 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10554683 0,14478088 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10554683 0,14469839 ! patterning of blood vessels GO:0001569 39 18 0,000 0,10554683 0,14461599 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10554683 0,14453368 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10554683 0,14445146 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10554683 0,14436934 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,10554683 0,14428731 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10554683 0,14420538 ! response to retinoic acid GO:0032526 26 18 0,000 0,10554683 0,14412354 ! response to fungus GO:0009620 21 18 0,000 0,10554683 0,14404179 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10554683 0,14396013 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10554683 0,14387857 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10554683 0,1437971 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10554683 0,14371572 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10554683 0,14363443 ! vitamin transport GO:0051180 27 18 0,000 0,10554683 0,14355323 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10554683 0,14347213 ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10554683 0,14339112 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10554683 0,1433102 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,10554683 0,14322937 ! nerve development GO:0021675 28 18 0,000 0,10554683 0,14314863 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10554683 0,14306798 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,10692648 0,14485648 ! protein secretion GO:0009306 39 19 0,000 0,1110742 0,15039084 ! negative regulation of defense response GO:0031348 25 19 0,000 0,1110742 0,15030626 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,1110742 0,15022177 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,1110742 0,15013737 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,1110742 0,15005307 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,1110742 0,14996887 ! bile acid metabolic process GO:0008206 29 19 0,000 0,1110742 0,14988476 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,1110742 0,14980074 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,1110742 0,14971682 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,1110742 0,14963299 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,1110742 0,14954926 ! heme metabolic process GO:0042168 36 19 0,000 0,1110742 0,14946562 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,1110742 0,14938207 ! plasma membrane fusion GO:0045026 28 19 0,000 0,1110742 0,14929862 ! protein export from nucleus GO:0006611 36 19 0,000 0,1110742 0,14921526 ! heart process GO:0003015 30 19 0,000 0,1110742 0,14913199 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,1110742 0,14904881 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,1110742 0,14896573 ! cellular pigmentation GO:0033059 36 19 0,000 0,1110742 0,14888274 ! G1 phase GO:0051318 40 19 0,000 0,1110742 0,14879985 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,1110742 0,14871704 ! cell-cell junction organization GO:0045216 35 19 0,000 0,1110742 0,14863433 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,1110742 0,14855171 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,1110742 0,14846918 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,1110742 0,14838674 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,1110742 0,1483044 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,1110742 0,14822214 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,1110742 0,14813998 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,1110742 0,14805791 ! cilium assembly GO:0042384 37 19 0,000 0,1110742 0,14797593 ! peptide hormone secretion GO:0030072 31 19 0,000 0,1110742 0,14789404 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,1128875 0,15022529 ! regulation of T cell activation GO:0050863 158 94 1,000 0,11489343 0,15281017 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11656759 0,15495118 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,11656759 0,15486562 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11656759 0,15478015 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11656759 0,15469478 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11656759 0,1546095 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,11656759 0,15452431 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11656759 0,15443922 ! response to vitamin GO:0033273 31 20 0,000 0,11656759 0,15435423 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11656759 0,15426932 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11656759 0,15418451 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11656759 0,1540998 ! response to alkaloid GO:0043279 38 20 0,000 0,11656759 0,15401517 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11656759 0,15393064 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11656759 0,1538462 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,11656759 0,15376186 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11656759 0,15367761 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11656759 0,15359344 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11656759 0,15350938 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11656759 0,1534254 ! body fluid secretion GO:0007589 31 20 0,000 0,11656759 0,15334151 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11656759 0,15325772 ! peptide secretion GO:0002790 35 20 0,000 0,11656759 0,15317402 ! stem cell differentiation GO:0048863 53 20 0,000 0,11656759 0,15309041 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11656759 0,15300689 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11656759 0,15292346 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11656759 0,15284013 ! sensory perception of pain GO:0019233 30 20 0,000 0,11656759 0,15275688 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11656759 0,15267372 ! diencephalon development GO:0021536 34 20 0,000 0,11656759 0,15259066 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11656759 0,15250768 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11656759 0,1524248 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11656759 0,152342 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11656759 0,1522593 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11656759 0,15217668 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11656759 0,15209416 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11656759 0,15201172 ! actin filament-based movement GO:0030048 43 20 0,000 0,11656759 0,15192938 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11656759 0,15184712 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11656759 0,15176495 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11656759 0,15168287 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11656759 0,15160088 ! forebrain development GO:0030900 188 95 1,000 0,1169085 0,15196211 ! detection of stimulus GO:0051606 151 96 1,000 0,11893253 0,15450954 ! regulation of cell killing GO:0031341 42 21 0,000 0,12202722 0,15844441 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12202722 0,15835895 ! hormone secretion GO:0046879 38 21 0,000 0,12202722 0,15827358 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12202722 0,15818831 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,12202722 0,15810312 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12202722 0,15801803 ! axis specification GO:0009798 38 21 0,000 0,12202722 0,15793303 ! ovarian follicle development GO:0001541 35 21 0,000 0,12202722 0,15784812 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12202722 0,1577633 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12202722 0,15767857 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,12202722 0,15759393 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12202722 0,15750939 ! cell aging GO:0007569 44 21 0,000 0,12202722 0,15742493 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12202722 0,15734057 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12202722 0,15725629 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,12202722 0,15717211 ! cytolysis GO:0019835 24 21 0,000 0,12202722 0,15708801 ! vasodilation GO:0042311 39 21 0,000 0,12202722 0,15700401 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12202722 0,15692009 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12202722 0,15683627 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12202722 0,15675253 ! oogenesis GO:0048477 36 21 0,000 0,12202722 0,15666889 ! DNA modification GO:0006304 34 21 0,000 0,12202722 0,15658533 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12202722 0,15650186 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12202722 0,15641848 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12202722 0,15633519 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12202722 0,15625199 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,12202722 0,15616888 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,12202722 0,15608586 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12202722 0,15600292 ! collagen catabolic process GO:0030574 28 21 0,000 0,12202722 0,15592007 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12202722 0,15583731 ! gut development GO:0048565 39 21 0,000 0,12202722 0,15575464 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,1250565 0,15953656 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,12711451 0,16207606 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12745329 0,16242194 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12745329 0,16233595 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12745329 0,16225006 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12745329 0,16216426 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12745329 0,16207855 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12745329 0,16199293 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12745329 0,1619074 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12745329 0,16182196 ! regeneration GO:0031099 41 22 0,000 0,12745329 0,16173661 ! keratinization GO:0031424 28 22 0,000 0,12745329 0,16165135 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12745329 0,16156618 ! sensory perception of taste GO:0050909 28 22 0,000 0,12745329 0,1614811 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12745329 0,16139611 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12745329 0,16131121 ! vacuolar transport GO:0007034 36 22 0,000 0,12745329 0,1612264 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12745329 0,16114168 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12745329 0,16105705 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12745329 0,1609725 ! fucose metabolic process GO:0006004 39 22 0,000 0,12745329 0,16088805 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12745329 0,16080368 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,12745329 0,1607194 ! ureteric bud development GO:0001657 43 22 0,000 0,12745329 0,16063521 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12745329 0,16055111 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12745329 0,16046709 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12745329 0,16038317 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12745329 0,16029933 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12745329 0,16021558 ! sarcomere organization GO:0045214 30 22 0,000 0,12745329 0,16013191 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,12745329 0,16004834 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12745329 0,15996485 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12745329 0,15988145 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12745329 0,15979813 ! protein stabilization GO:0050821 39 22 0,000 0,12745329 0,1597149 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,132846 0,16638599 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,132846 0,16629942 ! viral genome replication GO:0019079 41 23 0,000 0,132846 0,16621294 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,132846 0,16612655 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,132846 0,16604025 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,132846 0,16595404 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,132846 0,16586792 ! response to ethanol GO:0045471 46 23 0,000 0,132846 0,16578189 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,132846 0,16569595 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,132846 0,16561009 ! peroxisome organization GO:0007031 37 23 0,000 0,132846 0,16552433 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,132846 0,16543865 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,132846 0,16535307 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,132846 0,16526757 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,132846 0,16518216 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,132846 0,16509684 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,132846 0,16501161 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,132846 0,16492646 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,132846 0,1648414 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,132846 0,16475643 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,132846 0,16467155 ! fatty acid transport GO:0015908 44 23 0,000 0,132846 0,16458676 ! platelet activation GO:0030168 37 23 0,000 0,132846 0,16450205 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,132846 0,16441743 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,132846 0,1643329 ! hormone transport GO:0009914 40 23 0,000 0,132846 0,16424845 ! cell-cell recognition GO:0009988 25 23 0,000 0,132846 0,16416409 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,132846 0,16407982 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,132846 0,16399563 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,132846 0,16391153 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,13820556 0,170437 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,13820556 0,17034969 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13820556 0,17026246 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,13820556 0,17017533 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13820556 0,17008828 ! vesicle docking GO:0048278 47 24 0,000 0,13820556 0,17000132 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13820556 0,16991445 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13820556 0,16982767 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13820556 0,16974098 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13820556 0,16965438 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13820556 0,16956787 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13820556 0,16948144 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13820556 0,1693951 ! membrane depolarization GO:0051899 39 24 0,000 0,13820556 0,16930885 ! pentose metabolic process GO:0019321 35 24 0,000 0,13820556 0,16922269 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,13820556 0,16913662 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13820556 0,16905063 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13820556 0,16896473 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13820556 0,16887892 ! regulation of amine transport GO:0051952 40 24 0,000 0,13820556 0,16879319 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14353218 0,17520975 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14353218 0,1751209 ! phototransduction GO:0007602 33 25 0,000 0,14353218 0,17503214 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14353218 0,17494347 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,14353218 0,17485489 ! sperm motility GO:0030317 31 25 0,000 0,14353218 0,17476641 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14353218 0,17467801 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,14353218 0,1745897 ! receptor metabolic process GO:0043112 46 25 0,000 0,14353218 0,17450147 ! chromosome condensation GO:0030261 45 25 0,000 0,14353218 0,17441334 ! neural crest cell development GO:0014032 54 25 0,000 0,14353218 0,1743253 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14353218 0,17423734 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14353218 0,17414948 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14353218 0,1740617 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14353218 0,17397401 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,14353218 0,17388641 ! immunoglobulin production GO:0002377 55 25 0,000 0,14353218 0,1737989 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14353218 0,17371148 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14353218 0,17362414 ! telomere organization GO:0032200 43 25 0,000 0,14353218 0,17353689 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,14353218 0,17344973 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14882604 0,17975676 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14882604 0,17966656 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14882604 0,17957646 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14882604 0,17948645 ! initiation of viral infection GO:0019059 57 26 0,000 0,14882604 0,17939652 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14882604 0,17930669 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14882604 0,17921695 ! molting cycle process GO:0022404 50 26 0,000 0,14882604 0,17912729 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,14882604 0,17903773 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14882604 0,17894826 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14882604 0,17885887 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14882604 0,17876958 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,14882604 0,17868037 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14882604 0,17859125 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14882604 0,17850222 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14882604 0,17841328 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14882604 0,17832443 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14882604 0,17823567 ! blastocyst development GO:0001824 49 26 0,000 0,14882604 0,17814699 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14882604 0,17805841 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14882604 0,17796991 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14882604 0,1778815 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,15408736 0,18407855 ! neuron fate commitment GO:0048663 48 27 0,000 0,15408736 0,18398719 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,15408736 0,18389593 ! iron ion transport GO:0006826 59 27 0,000 0,15408736 0,18380476 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15408736 0,18371367 ! protein amino acid acylation GO:0043543 55 27 0,000 0,15408736 0,18362268 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15408736 0,18353178 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,15408736 0,18344097 ! fat cell differentiation GO:0045444 50 27 0,000 0,15408736 0,18335024 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15408736 0,18325961 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,15408736 0,18316907 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,15408736 0,18307861 ! autophagy GO:0006914 41 27 0,000 0,15408736 0,18298825 ! male gonad development GO:0008584 44 27 0,000 0,15408736 0,18289797 ! response to toxin GO:0009636 47 27 0,000 0,15408736 0,18280779 ! primary neural tube formation GO:0014020 51 27 0,000 0,15408736 0,18271769 ! base-excision repair GO:0006284 41 27 0,000 0,15408736 0,18262768 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15408736 0,18253776 ! glutathione metabolic process GO:0006749 39 27 0,000 0,15408736 0,18244793 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15408736 0,18235819 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15408736 0,18226853 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15408736 0,18217896 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15931633 0,18826871 ! circadian rhythm GO:0007623 50 28 0,000 0,15931633 0,18817629 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15931633 0,18808395 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15931633 0,18799171 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15931633 0,18789956 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15931633 0,1878075 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15931633 0,18771552 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15931633 0,18762364 ! synaptogenesis GO:0007416 42 28 0,000 0,15931633 0,18753185 ! lipid oxidation GO:0034440 43 28 0,000 0,15931633 0,18744015 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15931633 0,18734853 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15931633 0,18725701 ! translational initiation GO:0006413 65 29 0,000 0,16451315 0,19327083 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,16451315 0,1931765 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,16451315 0,19308227 ! regulation of pH GO:0006885 43 29 0,000 0,16451315 0,19298813 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,16451315 0,19289408 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16451315 0,19280012 ! catechol metabolic process GO:0009712 54 29 0,000 0,16451315 0,19270626 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,16451315 0,19261248 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16451315 0,1925188 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16451315 0,19242521 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16451315 0,19233171 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,16451315 0,1922383 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,16451315 0,19214498 ! cell fate determination GO:0001709 60 29 0,000 0,16451315 0,19205175 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16451315 0,19195861 ! detection of light stimulus GO:0009583 38 29 0,000 0,16451315 0,19186556 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,16451315 0,1917726 ! tissue homeostasis GO:0001894 48 29 0,000 0,16451315 0,19167973 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,16967802 0,1976018 ! zinc ion transport GO:0006829 45 30 0,000 0,16967802 0,1975062 ! membrane docking GO:0022406 61 30 0,000 0,16967802 0,1974107 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16967802 0,19731528 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16967802 0,19721996 ! acute-phase response GO:0006953 49 30 0,000 0,16967802 0,19712473 ! myofibril assembly GO:0030239 47 30 0,000 0,16967802 0,1970296 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16967802 0,19693455 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,16967802 0,1968396 ! phospholipid transport GO:0015914 51 30 0,000 0,16967802 0,19674473 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16967802 0,19664996 GO:0046496|nicotinamide nucleotide metabolic process, ! regulation of B cell activation GO:0050864 50 30 0,000 0,16967802 0,19655528 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17481113 0,20240404 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,17481113 0,20230668 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17481113 0,20220942 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17481113 0,20211225 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17481113 0,20201517 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17481113 0,20191819 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,17481113 0,2018213 ! ovulation cycle process GO:0022602 49 31 0,000 0,17481113 0,2017245 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17481113 0,2016278 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,17481113 0,20153119 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17481113 0,20143467 ! iron ion homeostasis GO:0055072 54 31 0,000 0,17481113 0,20133824 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,17481113 0,20124191 ! mesoderm formation GO:0001707 69 31 0,000 0,17481113 0,20114567 ! natural killer cell activation GO:0030101 45 31 0,000 0,17481113 0,20104952 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17481113 0,20095346 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17481113 0,20085749 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17481113 0,20076162 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,17481113 0,20066583 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,17481113 0,20057014 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17991268 0,20632503 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17991268 0,20622673 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17991268 0,20612853 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17991268 0,20603042 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17991268 0,2059324 ! spliceosome assembly GO:0000245 67 32 0,000 0,17991268 0,20583448 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17991268 0,20573665 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17991268 0,20563891 ! response to ionizing radiation GO:0010212 65 32 0,000 0,17991268 0,20554127 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17991268 0,20544372 ! muscle cell development GO:0055001 49 32 0,000 0,17991268 0,20534626 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17991268 0,20524889 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17991268 0,20515162 ! ovulation cycle GO:0042698 51 32 0,000 0,17991268 0,20505443 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17991268 0,20495734 ! hindbrain development GO:0030902 61 32 0,000 0,17991268 0,20486034 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,17991268 0,20476344 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17991268 0,20466662 ! gene silencing GO:0016458 65 32 0,000 0,17991268 0,2045699 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,18498286 0,21023559 ! post-embryonic development GO:0009791 69 33 0,000 0,18498286 0,21013633 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,18498286 0,21003716 ! protein targeting to membrane GO:0006612 68 33 0,000 0,18498286 0,20993809 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,18498286 0,20983911 ! formation of primary germ layer GO:0001704 72 33 0,000 0,18498286 0,20974022 ! cell fate specification GO:0001708 52 33 0,000 0,18498286 0,20964143 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,18498286 0,20954273 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,18498286 0,20944412 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,19002185 0,21504825 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,19002185 0,21494715 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,19002185 0,21484614 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,19002185 0,21474522 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,19002185 0,2146444 ! mismatch repair GO:0006298 46 34 0,000 0,19002185 0,21454368 ! spermatid development GO:0007286 63 34 0,000 0,19002185 0,21444305 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,19002185 0,21434251 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,19002185 0,21424207 ! regulation of muscle development GO:0048634 70 35 0,000 0,19502986 0,21978541 ! negative regulation of secretion GO:0051048 63 35 0,000 0,19502986 0,21968251 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,19502986 0,21957971 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,19502986 0,21947701 ! odontogenesis GO:0042476 66 35 0,000 0,19502986 0,2193744 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,19502986 0,21927189 ! female gonad development GO:0008585 58 35 0,000 0,19502986 0,21916948 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,19502986 0,21906716 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,19502986 0,21896493 ! cytokine production GO:0001816 59 35 0,000 0,19502986 0,2188628 ! neural tube formation GO:0001841 67 35 0,000 0,19502986 0,21876077 ! vesicle localization GO:0051648 64 35 0,000 0,19502986 0,21865883 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,20000707 0,22413461 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,20000707 0,22403027 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,20000707 0,22392602 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,20000707 0,22382187 ! positive regulation of cell development GO:0010720 80 36 0,000 0,20000707 0,22371781 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,20000707 0,22361386 ! regulation of proteolysis GO:0030162 72 36 0,000 0,20000707 0,22350999 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,20000707 0,22340623 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,20000707 0,22330256 ! embryonic organ development GO:0048568 57 36 0,000 0,20000707 0,22319899 ! RNA export from nucleus GO:0006405 56 37 0,000 0,20495367 0,22861314 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,20495367 0,2285072 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,20495367 0,22840136 ! actomyosin structure organization GO:0031032 62 37 0,000 0,20495367 0,22829562 ! organic anion transport GO:0015711 68 37 0,000 0,20495367 0,22818998 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,20495367 0,22808443 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,20495367 0,22797898 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,20495367 0,22787363 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,20495367 0,22776838 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,20495367 0,22766322 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,20495367 0,22755816 ! pigment metabolic process GO:0042440 80 37 0,000 0,20495367 0,2274532 ! spermatid differentiation GO:0048515 66 37 0,000 0,20495367 0,22734833 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20986985 0,23269441 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20986985 0,23258722 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20986985 0,23248014 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20986985 0,23237315 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,20986985 0,23226626 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,20986985 0,23215948 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20986985 0,23205278 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,20986985 0,23194619 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20986985 0,2318397 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,20986985 0,2317333 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,20986985 0,231627 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20986985 0,2315208 ! mRNA catabolic process GO:0006402 71 39 0,000 0,21475579 0,23680221 ! ear morphogenesis GO:0042471 60 39 0,000 0,21475579 0,23669374 ! organic ether metabolic process GO:0018904 55 39 0,000 0,21475579 0,23658536 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,21475579 0,23647709 ! segmentation GO:0035282 67 39 0,000 0,21475579 0,23636891 ! ion transmembrane transport GO:0034220 66 39 0,000 0,21475579 0,23626083 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,21475579 0,23615285 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,21475579 0,23604497 ! RNA modification GO:0009451 57 39 0,000 0,21475579 0,23593718 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,21475579 0,2358295 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21961168 0,24105187 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21961168 0,24094195 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21961168 0,24083213 ! feeding behavior GO:0007631 59 40 0,000 0,21961168 0,24072241 ! negative regulation of binding GO:0051100 72 40 0,000 0,21961168 0,2406128 ! mesenchymal cell development GO:0014031 87 40 0,000 0,21961168 0,24050328 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21961168 0,24039386 ! maintenance of protein location GO:0045185 91 40 0,000 0,21961168 0,24028454 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,2244377 0,24545323 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,2244377 0,24534171 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,2244377 0,24523029 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,2244377 0,24511898 ! T cell differentiation GO:0030217 81 41 0,000 0,2244377 0,24500776 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,2244377 0,24489665 ! female gamete generation GO:0007292 61 41 0,000 0,2244377 0,24478563 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,2244377 0,24467472 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,22923404 0,24979035 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,22923404 0,24967727 ! regulation of tube size GO:0035150 71 42 0,000 0,22923404 0,24956429 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22923404 0,24945142 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,22923404 0,24933865 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22923404 0,24922598 ! neuron migration GO:0001764 79 42 0,000 0,22923404 0,24911341 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22923404 0,24900094 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,22923404 0,24888858 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,23400087 0,25394952 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,23400087 0,25383503 ! glucose transport GO:0015758 65 43 0,000 0,23400087 0,25372063 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,23400087 0,25360635 ! neural tube development GO:0021915 77 43 0,000 0,23400087 0,25349216 ! striated muscle contraction GO:0006941 77 43 0,000 0,23400087 0,25337808 ! hexose transport GO:0008645 67 44 0,000 0,23873838 0,2583916 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,23873838 0,25827542 ! double-strand break repair GO:0006302 81 44 0,000 0,23873838 0,25815934 ! biopolymer methylation GO:0043414 84 44 0,000 0,23873838 0,25804337 ! B cell differentiation GO:0030183 107 44 0,000 0,23873838 0,2579275 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23873838 0,25781173 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,23873838 0,25769607 ! developmental growth GO:0048589 82 44 0,000 0,23873838 0,25758051 ! maintenance of location in cell GO:0051651 97 44 0,000 0,23873838 0,25746505 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,24344674 0,26242512 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,24344674 0,2623076 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,24344674 0,26219018 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,24344674 0,26207287 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,24344674 0,26195566 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,24344674 0,26183856 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,24344674 0,26172156 ! cell growth GO:0016049 84 45 0,000 0,24344674 0,26160467 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,24812614 0,26651406 ! endosome transport GO:0016197 108 47 0,000 0,25277675 0,27138816 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,25277675 0,27126711 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,25277675 0,27114617 ! JNK cascade GO:0007254 91 47 0,000 0,25277675 0,27102534 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,25277675 0,27090462 ! methylation GO:0032259 90 47 0,000 0,25277675 0,270784 ! mitochondrial transport GO:0006839 82 48 0,000 0,25739875 0,27561255 ! Notch signaling pathway GO:0007219 96 48 0,000 0,25739875 0,27548995 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,25739875 0,27536745 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,25739875 0,27524507 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25739875 0,27512279 ! activation of caspase activity GO:0006919 84 48 0,000 0,25739875 0,27500062 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,26199231 0,27978407 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,26199231 0,27965994 ! regulation of ion transport GO:0043269 77 49 0,000 0,26199231 0,27953592 ! peptide metabolic process GO:0006518 76 49 0,000 0,26199231 0,27941202 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,26199231 0,27928822 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,26199231 0,27916453 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,26199231 0,27904095 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 0,000 0,26655761 0,28377771 ! regulation of ossification GO:0030278 117 50 0,000 0,26655761 0,2836522 ! inner ear development GO:0048839 79 50 0,000 0,26655761 0,2835268 ! histone modification GO:0016570 91 50 0,000 0,26655761 0,28340151 ! positive regulation of binding GO:0051099 78 51 0,000 0,27109482 0,28809812 ! viral infectious cycle GO:0019058 99 51 0,000 0,27109482 0,28797093 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,27109482 0,28784384 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,27109482 0,28771687 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,27109482 0,28759001 ! excretion GO:0007588 83 51 0,000 0,27109482 0,28746326 ! chromatin remodeling GO:0006338 109 51 0,000 0,27109482 0,28733663 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,27109482 0,2872101 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,27109482 0,28708369 ! vesicle organization GO:0016050 107 51 0,000 0,27109482 0,28695739 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,27109482 0,2868312 ! membrane fusion GO:0006944 110 52 0,000 0,27560412 0,29147407 ! covalent chromatin modification GO:0016569 101 52 0,000 0,27560412 0,291346 ! amino acid activation GO:0043038 92 52 0,000 0,27560412 0,29121805 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,28008566 0,29582357 ! RNA catabolic process GO:0006401 93 53 0,000 0,28008566 0,29569377 ! regulation of translational initiation GO:0006446 82 53 0,000 0,28008566 0,29556408 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,28008566 0,2954345 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,28008566 0,29530504 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,28008566 0,29517569 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,28008566 0,29504645 ! cell recognition GO:0008037 85 54 0,000 0,28453963 0,29960715 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,28453963 0,29947609 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,28453963 0,29934514 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,28453963 0,29921431 ! chloride transport GO:0006821 90 55 0,000 0,28896619 0,30373641 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,28896619 0,30360377 GO:0010952|positive regulation of peptidase activity, ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,28896619 0,30347125 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,28896619 0,30333885 ! aging GO:0007568 103 55 0,000 0,28896619 0,30320656 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,28896619 0,30307439 ! nuclear export GO:0051168 97 55 0,000 0,28896619 0,30294233 ! regulation of actin filament length GO:0030832 105 56 0,000 0,2933655 0,30742047 ! sensory perception of smell GO:0007608 80 56 0,000 0,2933655 0,30728664 ! proton transport GO:0015992 94 56 0,000 0,2933655 0,30715292 ! maintenance of location GO:0051235 118 57 0,000 0,29773775 0,31159505 ! hydrogen transport GO:0006818 97 58 0,000 0,30208308 0,31600517 ! positive regulation of secretion GO:0051047 95 59 0,000 0,30640167 0,3203835 ! regulation of cellular component size GO:0032535 109 59 0,000 0,30640167 0,32024432 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,30640167 0,32010527 GO:0032313|regulation of Rab GTPase activity, ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,31069369 0,32444835 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,31069369 0,3243076 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,31495928 0,32861753 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,31495928 0,32847509 ! mesoderm development GO:0007498 119 61 0,000 0,31495928 0,32833277 ! tRNA processing GO:0008033 89 61 0,000 0,31495928 0,32819057 ! ear development GO:0043583 103 62 0,000 0,31919862 0,33246402 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,31919862 0,33232015 ! gonad development GO:0008406 98 62 0,000 0,31919862 0,33217642 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,32341186 0,33641545 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,32341186 0,33627007 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,32341186 0,33612481 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,32341186 0,33597968 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,32759917 0,34018283 ! cell redox homeostasis GO:0045454 102 64 0,000 0,32759917 0,34003607 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,32759917 0,33988944 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,32759917 0,33974294 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,32759917 0,33959656 ! germ cell development GO:0007281 118 65 0,000 0,33176071 0,34376239 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,33176071 0,3436144 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,33589662 0,34774839 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,33589662 0,34759883 ! secondary metabolic process GO:0019748 116 66 0,000 0,33589662 0,34744938 ! cell projection assembly GO:0030031 120 66 0,000 0,33589662 0,34730007 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,34000707 0,35139906 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,34000707 0,35124818 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,34000707 0,35109743 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,34000707 0,35094681 ! activation of immune response GO:0002253 105 67 0,000 0,34000707 0,35079632 ! amino acid transport GO:0006865 125 68 0,000 0,34409222 0,35485893 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,34409222 0,35470689 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,34409222 0,35455498 ! negative regulation of cell size GO:0045792 134 69 0,000 0,34815222 0,35858486 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,34815222 0,35843142 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,34815222 0,35827812 ! antigen processing and presentation GO:0019882 104 69 0,000 0,34815222 0,35812494 ! amine catabolic process GO:0009310 117 71 0,000 0,35619738 0,36624397 ! humoral immune response GO:0006959 109 71 0,000 0,35619738 0,36608752 ! B cell activation GO:0042113 160 71 0,000 0,35619738 0,36593121 ! acute inflammatory response GO:0002526 113 72 0,000 0,36018284 0,36986765 ! carbohydrate transport GO:0008643 110 72 0,000 0,36018284 0,36970986 ! regulation of blood pressure GO:0008217 125 73 0,000 0,36414377 0,37361616 ! fertilization GO:0009566 90 73 0,000 0,36414377 0,37345691 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,3680803 0,37733328 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,3680803 0,37717257 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,3680803 0,37701201 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,3680803 0,37685158 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,3719926 0,3806951 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,3719926 0,38053324 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,3758808 0,3843473 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,3758808 0,38418403 ! defense response to bacterium GO:0042742 89 76 0,000 0,3758808 0,38402089 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,37974506 0,38780416 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,37974506 0,38763963 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,37974506 0,38747523 ! blood coagulation GO:0007596 146 78 0,000 0,38358552 0,39122796 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,38740232 0,39495339 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,38740232 0,3947861 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,38740232 0,39461896 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,38740232 0,39445196 ! muscle cell differentiation GO:0042692 159 80 0,000 0,39119562 0,3981458 ! protein import into nucleus GO:0006606 158 80 0,000 0,39119562 0,39797745 ! inorganic anion transport GO:0015698 138 80 0,000 0,39119562 0,39780924 ! T cell activation GO:0042110 168 81 0,000 0,39496556 0,40147323 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,39496556 0,40130369 ! nuclear import GO:0051170 161 81 0,000 0,39496556 0,40113429 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,39496556 0,40096504 ! response to nutrient GO:0007584 125 82 0,000 0,39871228 0,40459795 ! hemostasis GO:0007599 158 84 0,000 0,40613662 0,41195814 ! negative regulation of growth GO:0045926 155 84 0,000 0,40613662 0,41178454 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,40613662 0,41161108 ! response to unfolded protein GO:0006986 131 85 0,000 0,40981453 0,41516369 ! nucleosome assembly GO:0006334 122 85 0,000 0,40981453 0,41498896 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,40981453 0,41481437 ! amine biosynthetic process GO:0009309 138 86 0,000 0,41346978 0,41833822 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,41346978 0,41816238 ! chromatin assembly GO:0031497 124 86 0,000 0,41346978 0,41798668 ! mitochondrion organization GO:0007005 148 86 0,000 0,41346978 0,41781113 ! amine transport GO:0015837 155 86 0,000 0,41346978 0,41763572 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,41710251 0,42112826 ! protein localization in nucleus GO:0034504 176 87 0,000 0,41710251 0,42095161 ! regulation of DNA binding GO:0051101 155 88 0,000 0,42071287 0,42441726 ! regulation of neurological system process GO:0031644 148 88 0,000 0,42071287 0,42423938 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,42071287 0,42406165 ! cellular defense response GO:0006968 114 89 0,000 0,42430098 0,42749923 ! sex differentiation GO:0007548 145 90 0,000 0,42786699 0,43091166 ! response to protein stimulus GO:0051789 149 91 0,000 0,43141102 0,43429913 ! nucleosome organization GO:0034728 138 92 0,000 0,43493322 0,43766178 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,43493322 0,43747882 ! vitamin metabolic process GO:0006766 139 92 0,000 0,43493322 0,437296 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,44191264 0,44412775 ! female pregnancy GO:0007565 164 94 0,000 0,44191264 0,44394231 ! leukocyte differentiation GO:0002521 202 96 0,000 0,44880632 0,45067947 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,44880632 0,45049145 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,44880632 0,45030359 ! positive regulation of immune response GO:0050778 156 96 0,000 0,44880632 0,45011588 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,45222133 0,45335188 ! protein ubiquitination GO:0016567 217 97 0,000 0,45222133 0,45316307 ! response to virus GO:0009615 160 98 0,000 0,4556153 0,45637402 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,4556153 0,4561841 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,4556153 0,45599434 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,45898834 0,45917919 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,45898834 0,45898834