pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6878-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! actin cytoskeleton reorganization GO:0031532 5 5 2,000 2,772E-06 5,108E-03 ! sex determination GO:0007530 8 8 2,000 1,53E-05 0,01410351 ! regulation of mitotic cell cycle GO:0007346 72 69 4,000 8,733E-05 0,05364939 ! regulation of mitosis GO:0007088 37 36 3,000 8,812E-05 0,04060212 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 36 36 3,000 8,812E-05 0,03248169 ! wound healing GO:0042060 74 70 4,000 9,358E-05 0,02874479 ! negative regulation of ligase activity GO:0051352 43 42 3,000 1,626E-04 0,0428134 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 3,000 1,626E-04 0,03746173 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 3,000 2,325E-04 0,04760906 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 2,515E-04 0,04635349 ! heart development GO:0007507 90 87 4,000 2,625E-04 0,04398693 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 3,000 2,745E-04 0,04216289 ! regulation of cell cycle process GO:0010564 50 48 3,000 2,745E-04 0,03891959 ! regulation of ligase activity GO:0051340 50 49 3,000 2,975E-04 0,0391605 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 4,318E-04 0,05305479 ! prostate gland development GO:0030850 5 5 1,000 4,318E-04 0,04973887 ! memory GO:0007613 5 5 1,000 4,318E-04 0,04681305 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 4,318E-04 0,04421233 ! receptor clustering GO:0043113 5 5 1,000 4,318E-04 0,04188536 ! cellular glucose homeostasis GO:0001678 5 5 1,000 4,318E-04 0,0397911 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 4,318E-04 0,03789628 ! protein heterooligomerization GO:0051291 5 5 1,000 4,318E-04 0,03617372 ! regulation of DNA replication initiation GO:0030174 5 5 1,000 4,318E-04 0,03460095 ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,318E-04 0,03315925 ! reproductive developmental process GO:0003006 56 56 3,000 4,984E-04 0,03673981 ! glucose homeostasis GO:0042593 24 24 2,000 5,132E-04 0,03637691 GO:0033500|carbohydrate homeostasis, ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 6,45E-04 0,04402401 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 6,45E-04 0,04245173 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 6,45E-04 0,04098787 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 6,45E-04 0,03962161 GO:0070667|negative regulation of mast cell proliferation, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 6,45E-04 0,03834349 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 6,45E-04 0,03714526 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 6,45E-04 0,03601965 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 6,45E-04 0,03496025 ! proteasomal protein catabolic process GO:0010498 62 61 3,000 6,91E-04 0,03638862 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 8,152E-04 0,04173513 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 8,991E-04 0,0447844 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 8,991E-04 0,04360586 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 8,991E-04 0,04248776 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! axon cargo transport GO:0008088 7 7 1,000 8,991E-04 0,04142557 ! negative regulation of T cell activation GO:0050868 7 7 1,000 8,991E-04 0,04041519 ! regulation of DNA replication GO:0006275 32 31 2,000 1,103E-03 0,04840041 ! negative regulation of cell motion GO:0051271 31 31 2,000 1,103E-03 0,04727482 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,194E-03 0,04999912 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 1,000 1,194E-03 0,04888803 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,194E-03 0,04782525 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,194E-03 0,04680769 ! regulation of angiogenesis GO:0045765 35 34 2,000 1,448E-03 0,05559441 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,528E-03 0,05747938 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,528E-03 0,05632979 ! histone acetylation GO:0016573 9 9 1,000 1,528E-03 0,05522529 ! collagen catabolic process GO:0030574 9 9 1,000 1,528E-03 0,05416326 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,576E-03 0,05481333 ! coagulation GO:0050817 39 36 2,000 1,712E-03 0,0584156 GO:0007596|blood coagulation, ! regulation of cell motion GO:0051270 79 79 3,000 1,823E-03 0,06107716 ! regulation of transcription factor activity GO:0051090 38 37 2,000 1,854E-03 0,06101405 GO:0090046|regulation of transcription regulator activity, ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 1,902E-03 0,0615025 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,902E-03 0,06044211 ! plasma membrane organization GO:0007009 10 10 1,000 1,902E-03 0,05941767 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,902E-03 0,05842737 ! neuromuscular junction development GO:0007528 10 10 1,000 1,902E-03 0,05746955 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 1,902E-03 0,05654262 ! mRNA splice site selection GO:0006376 11 10 1,000 1,902E-03 0,05564512 ! negative regulation of coagulation GO:0050819 11 10 1,000 1,902E-03 0,05477566 ! protein stabilization GO:0050821 10 10 1,000 1,902E-03 0,05393296 ! hemostasis GO:0007599 42 39 2,000 2,16E-03 0,06032507 ! positive regulation of cell motion GO:0051272 39 39 2,000 2,16E-03 0,0594247 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 2,315E-03 0,06274211 ! signal complex assembly GO:0007172 11 11 1,000 2,315E-03 0,0618328 ! microtubule-based transport GO:0010970 11 11 1,000 2,315E-03 0,06094948 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,315E-03 0,06009103 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 2,315E-03 0,05925643 GO:0032388|positive regulation of intracellular transport, ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 2,315E-03 0,0584447 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 2,315E-03 0,05765491 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 2,315E-03 0,05688618 ! intermediate filament-based process GO:0045103 11 11 1,000 2,315E-03 0,05613768 ! interaction with host GO:0051701 11 11 1,000 2,315E-03 0,05540861 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,315E-03 0,05469825 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,315E-03 0,05400586 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,496E-03 0,05751198 ! heterophilic cell adhesion GO:0007157 12 12 1,000 2,766E-03 0,06293834 ! collagen metabolic process GO:0032963 12 12 1,000 2,766E-03 0,0621708 ! C21-steroid hormone metabolic process GO:0008207 13 12 1,000 2,766E-03 0,06142175 ! positive regulation of endocytosis GO:0045807 12 12 1,000 2,766E-03 0,06069054 ! somitogenesis GO:0001756 13 12 1,000 2,766E-03 0,05997654 ! G1 phase GO:0051318 13 12 1,000 2,766E-03 0,05927913 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 2,766E-03 0,05859777 ! negative regulation of translation GO:0017148 12 12 1,000 2,766E-03 0,05793188 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 2,766E-03 0,05728096 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 3,059E-03 0,06263154 ! positive regulation of DNA replication GO:0045740 14 13 1,000 3,255E-03 0,06592671 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 3,255E-03 0,06521012 ! negative regulation of DNA replication GO:0008156 13 13 1,000 3,255E-03 0,06450894 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 3,255E-03 0,06382267 ! multicellular organismal catabolic process GO:0044243 13 13 1,000 3,255E-03 0,06315085 ! receptor metabolic process GO:0043112 14 13 1,000 3,255E-03 0,06249303 ! actin filament bundle formation GO:0051017 13 13 1,000 3,255E-03 0,06184877 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 3,255E-03 0,06121766 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,255E-03 0,0605993 ! protein tetramerization GO:0051262 13 13 1,000 3,255E-03 0,05999331 ! regulation of DNA binding GO:0051101 47 45 2,000 3,262E-03 0,0595187 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 3,262E-03 0,05893518 ! positive regulation of ligase activity GO:0051351 47 46 2,000 3,473E-03 0,0621446 ! regulation of catabolic process GO:0009894 48 47 2,000 3,693E-03 0,0654379 ! protein amino acid acylation GO:0043543 14 14 1,000 3,782E-03 0,06637629 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 3,782E-03 0,0657501 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 3,782E-03 0,06513561 ! regulation of blood coagulation GO:0030193 15 14 1,000 3,782E-03 0,0645325 ! calcium ion transport GO:0006816 48 48 2,000 3,921E-03 0,06628912 ! actin filament organization GO:0007015 50 48 2,000 3,921E-03 0,06568649 ! gland development GO:0048732 51 49 2,000 4,157E-03 0,06901791 ! divalent metal ion transport GO:0070838 49 49 2,000 4,157E-03 0,06840168 ! skeletal muscle tissue development GO:0007519 50 49 2,000 4,157E-03 0,06779635 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 4,157E-03 0,06720165 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 4,345E-03 0,06963151 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 4,345E-03 0,06903124 ! response to starvation GO:0042594 15 15 1,000 4,345E-03 0,06844123 ! glutathione metabolic process GO:0006749 16 15 1,000 4,345E-03 0,06786122 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 4,345E-03 0,06729095 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 4,345E-03 0,0667302 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 4,402E-03 0,06704243 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 4,402E-03 0,06649291 ! ATP biosynthetic process GO:0006754 51 51 2,000 4,655E-03 0,06974895 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 4,917E-03 0,0730815 ! regulation of body fluid levels GO:0050878 55 52 2,000 4,917E-03 0,07249685 ! segmentation GO:0035282 17 16 1,000 4,945E-03 0,07232348 ! cellular response to nutrient levels GO:0031669 16 16 1,000 4,945E-03 0,07175401 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 4,945E-03 0,07119343 ! positive regulation of catabolic process GO:0009896 16 16 1,000 4,945E-03 0,07064154 ! regulation of coagulation GO:0050818 17 16 1,000 4,945E-03 0,07009814 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 4,945E-03 0,06956304 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! response to hypoxia GO:0001666 53 53 2,000 5,188E-03 0,0724337 ! response to oxygen levels GO:0070482 55 54 2,000 5,468E-03 0,07576465 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 5,58E-03 0,07674637 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,58E-03 0,07617787 ! myelination GO:0042552 17 17 1,000 5,58E-03 0,07561774 ! regulation of transmembrane transport GO:0034762 17 17 1,000 5,58E-03 0,07506579 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 5,58E-03 0,07452183 ! leukocyte adhesion GO:0007159 17 17 1,000 5,58E-03 0,07398571 ! cell junction assembly GO:0034329 18 17 1,000 5,58E-03 0,07345724 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 2,000 5,756E-03 0,0752383 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 2,000 6,054E-03 0,07857111 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 6,251E-03 0,08056288 ! response to calcium ion GO:0051592 18 18 1,000 6,251E-03 0,08000342 ! negative regulation of DNA binding GO:0043392 19 18 1,000 6,251E-03 0,07945167 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 6,251E-03 0,07890748 ! ensheathment of neurons GO:0007272 18 18 1,000 6,251E-03 0,0783707 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 6,251E-03 0,07784116 ! negative regulation of catabolic process GO:0009895 18 18 1,000 6,251E-03 0,07731874 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 6,251E-03 0,07680328 ! regulation of binding GO:0051098 60 57 2,000 6,36E-03 0,07763129 ! ATP metabolic process GO:0046034 57 57 2,000 6,36E-03 0,07712055 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 2,000 6,36E-03 0,0766165 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 6,957E-03 0,08325527 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 6,957E-03 0,08271813 ! peripheral nervous system development GO:0007422 19 19 1,000 6,957E-03 0,08218789 ! regulation of protein stability GO:0031647 19 19 1,000 6,957E-03 0,0816644 ! hormone biosynthetic process GO:0042446 19 19 1,000 6,957E-03 0,08114754 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 7,001E-03 0,08115403 ! negative regulation of binding GO:0051100 21 20 1,000 7,697E-03 0,08865995 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 7,697E-03 0,08810926 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 7,697E-03 0,08756538 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 2,000 8,032E-03 0,09082121 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 2,000 8,032E-03 0,09026742 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 2,000 8,395E-03 0,09377011 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 2,000 8,395E-03 0,09320523 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 8,471E-03 0,09348781 ! mammary gland development GO:0030879 23 21 1,000 8,471E-03 0,09293134 ! spliceosome assembly GO:0000245 22 21 1,000 8,471E-03 0,09238145 ! DNA integrity checkpoint GO:0031570 21 21 1,000 8,471E-03 0,09183803 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 8,471E-03 0,09130097 ! regulation of action potential in neuron GO:0019228 21 21 1,000 8,471E-03 0,09077015 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 8,471E-03 0,09024546 ! negative regulation of protein transport GO:0051224 21 21 1,000 8,471E-03 0,08972681 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 9,279E-03 0,09772041 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 9,279E-03 0,09716518 ! sister chromatid segregation GO:0000819 22 22 1,000 9,279E-03 0,09661622 ! cell junction organization GO:0034330 23 22 1,000 9,279E-03 0,09607344 ! maintenance of protein location in cell GO:0032507 23 22 1,000 9,279E-03 0,09553671 ! nucleoside triphosphate metabolic process GO:0009141 66 66 2,000 9,54E-03 0,09768017 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 9,54E-03 0,0971405 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 9,54E-03 0,09660676 ! striated muscle tissue development GO:0014706 69 67 2,000 9,941E-03 0,1001172 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01011967 0,10136173 ! positive regulation of growth GO:0045927 23 23 1,000 0,01011967 0,10081383 ! cell projection assembly GO:0030031 25 23 1,000 0,01011967 0,10027182 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 2,000 0,01035182 0,10202351 ! regulation of action potential GO:0001508 24 24 1,000 0,01099299 0,10776639 ! maintenance of protein location GO:0045185 25 24 1,000 0,01099299 0,1071962 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01099299 0,10663201 ! positive regulation of transport GO:0051050 71 70 2,000 0,01120261 0,10809642 ! muscle tissue development GO:0060537 72 70 2,000 0,01120261 0,10753342 ! regulation of cell migration GO:0030334 71 71 2,000 0,01164278 0,11117951 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01189843 0,11303508 ! endosome transport GO:0016197 25 25 1,000 0,01189843 0,11245542 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01189843 0,11188166 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01189843 0,11131374 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01189843 0,11075155 ! heart morphogenesis GO:0003007 25 25 1,000 0,01189843 0,11019501 ! regulation of endocytosis GO:0030100 25 25 1,000 0,01189843 0,10964403 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01189843 0,10909854 ! positive regulation of binding GO:0051099 27 26 1,000 0,01283554 0,11710843 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01283554 0,11653154 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01283554 0,11596031 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01283554 0,11539465 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01283554 0,11483448 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01283554 0,11427973 ! synapse organization GO:0050808 26 26 1,000 0,01283554 0,1137303 ! ribonucleotide biosynthetic process GO:0009260 75 75 2,000 0,01350279 0,11907007 ! purine ribonucleotide metabolic process GO:0009150 75 75 2,000 0,01350279 0,11850306 ! chloride transport GO:0006821 27 27 1,000 0,01380388 0,12057134 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01380388 0,12000261 ! learning or memory GO:0007611 28 27 1,000 0,01380388 0,11943922 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01380388 0,11888109 ! peptide metabolic process GO:0006518 29 27 1,000 0,01380388 0,11832816 ! cell growth GO:0016049 27 27 1,000 0,01380388 0,11778034 ! histone modification GO:0016570 28 28 1,000 0,01480301 0,12572325 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01480301 0,12514654 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,01500303 0,12625837 ! regulation of locomotion GO:0040012 79 79 2,000 0,01552331 0,13004297 ! viral reproductive process GO:0022415 29 29 1,000 0,01583249 0,13203291 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,01583249 0,13143817 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01583249 0,13084876 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,01583249 0,13026461 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01583249 0,12968566 ! ribonucleotide metabolic process GO:0009259 83 83 2,000 0,017706 0,14439011 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01798077 0,14598487 ! ribonucleoprotein complex assembly GO:0022618 32 31 1,000 0,01798077 0,14534459 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01798077 0,1447099 ! muscle fiber development GO:0048747 32 32 1,000 0,01909873 0,15303896 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,01909873 0,15237645 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01909873 0,15171966 ! maintenance of location GO:0051235 33 32 1,000 0,01909873 0,1510685 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 0,01945021 0,15319115 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,01945021 0,15253927 ! positive regulation of transferase activity GO:0051347 91 88 2,000 0,02066425 0,16137378 GO:0033674|positive regulation of kinase activity, ! purine nucleotide biosynthetic process GO:0006164 88 88 2,000 0,02066425 0,16069288 ! response to metal ion GO:0010038 34 34 1,000 0,02142017 0,16587134 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,02142017 0,16517732 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02142017 0,16448908 ! viral reproduction GO:0016032 34 34 1,000 0,02142017 0,16380656 ! inorganic anion transport GO:0015698 35 35 1,000 0,02262283 0,17228877 ! response to inorganic substance GO:0010035 36 36 1,000 0,02385291 0,18090908 ! positive regulation of cell migration GO:0030335 36 36 1,000 0,02385291 0,18016765 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,02385291 0,17943227 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02510999 0,18812079 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 1,000 0,02510999 0,18735917 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 1,000 0,02510999 0,18660369 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,02639369 0,19535569 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,02639369 0,19457426 ! chromosome segregation GO:0007059 38 38 1,000 0,02639369 0,19379907 ! urogenital system development GO:0001655 38 38 1,000 0,02639369 0,19303002 ! RNA elongation GO:0006354 38 38 1,000 0,02639369 0,19226706 ! meiotic cell cycle GO:0051321 38 38 1,000 0,02639369 0,1915101 ! axon guidance GO:0007411 39 38 1,000 0,02639369 0,19075908 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,02639369 0,19001393 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,02735121 0,19614119 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,0277036 0,19789819 ! activation of MAPK activity GO:0000187 39 39 1,000 0,0277036 0,19713411 ! respiratory tube development GO:0030323 40 39 1,000 0,0277036 0,1963759 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,0277036 0,1956235 ! respiratory system development GO:0060541 40 39 1,000 0,0277036 0,19487685 ! protein oligomerization GO:0051259 39 39 1,000 0,0277036 0,19413587 ! muscle organ development GO:0007517 102 100 2,000 0,02881194 0,20113788 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02903934 0,20196037 ! DNA catabolic process GO:0006308 41 40 1,000 0,02903934 0,20120112 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,02903934 0,20044755 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03040051 0,20906022 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,03178674 0,2177805 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,03178674 0,21697391 ! rRNA transcription GO:0009303 5 5 0,000 0,03299564 0,22439473 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03299564 0,22356975 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03299564 0,22275081 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03299564 0,22193785 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03299564 0,22113081 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03299564 0,22032961 ! reproductive cellular process GO:0048610 5 5 0,000 0,03299564 0,2195342 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03299564 0,2187445 ! metencephalon development GO:0022037 5 5 0,000 0,03299564 0,21796047 ! water transport GO:0006833 5 5 0,000 0,03299564 0,21718204 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03299564 0,21640915 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03299564 0,21564175 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03299564 0,21487976 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03299564 0,21412314 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03299564 0,21337183 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03299564 0,21262578 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03299564 0,21188492 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03299564 0,21114921 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03299564 0,21041859 ! filopodium assembly GO:0046847 7 5 0,000 0,03299564 0,20969301 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03299564 0,20897241 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03299564 0,20825675 ! GTP metabolic process GO:0046039 5 5 0,000 0,03299564 0,20754598 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03299564 0,20684004 ! mRNA stabilization GO:0048255 5 5 0,000 0,03299564 0,20613889 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03299564 0,20544247 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03299564 0,20475075 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03299564 0,20406367 ! social behavior GO:0035176 5 5 0,000 0,03299564 0,20338118 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03299564 0,20270324 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03299564 0,20202981 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03299564 0,20136084 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03299564 0,20069628 ! response to lipid GO:0033993 5 5 0,000 0,03299564 0,20003609 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03299564 0,19938024 ! hippocampus development GO:0021766 6 5 0,000 0,03299564 0,19872867 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03299564 0,19808134 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03299564 0,19743822 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03299564 0,19679926 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03299564 0,19616443 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03299564 0,19553367 ! heart looping GO:0001947 5 5 0,000 0,03299564 0,19490696 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03299564 0,19428426 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03299564 0,19366552 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03299564 0,19305071 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03299564 0,19243979 ! pH reduction GO:0045851 5 5 0,000 0,03299564 0,19183272 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03299564 0,19122947 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03299564 0,19063001 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03299564 0,19003429 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03299564 0,18944228 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03299564 0,18885395 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03299564 0,18826926 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03299564 0,18768819 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03299564 0,18711068 ! adrenal gland development GO:0030325 5 5 0,000 0,03299564 0,18653672 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03299564 0,18596628 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03299564 0,18539931 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03299564 0,18483578 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03299564 0,18427567 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03299564 0,18371895 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03299564 0,18316558 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03299564 0,18261553 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03299564 0,18206878 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03299564 0,18152529 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03299564 0,18098504 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03299564 0,18044799 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03299564 0,17991412 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03299564 0,1793834 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03299564 0,1788558 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03299564 0,1783313 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03299564 0,17780986 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03299564 0,17729146 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03299564 0,17677608 ! response to ATP GO:0033198 5 5 0,000 0,03299564 0,17626369 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03299564 0,17575425 ! regulation of appetite GO:0032098 5 5 0,000 0,03299564 0,17524776 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03299564 0,17474417 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03299564 0,17424347 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,03299564 0,17374563 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03299564 0,17325063 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03299564 0,17275844 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03299564 0,17226904 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03299564 0,17178241 ! fear response GO:0042596 5 5 0,000 0,03299564 0,17129851 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03299564 0,17081734 ! retinol metabolic process GO:0042572 5 5 0,000 0,03299564 0,17033886 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03299564 0,16986305 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03299564 0,16938989 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03299564 0,16891937 ! parturition GO:0007567 5 5 0,000 0,03299564 0,16845145 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03299564 0,16798611 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03299564 0,16752334 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03299564 0,16706311 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03299564 0,1666054 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03299564 0,1661502 ! response to UV-B GO:0010224 5 5 0,000 0,03299564 0,16569747 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03299564 0,16524721 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03299564 0,16479938 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03299564 0,16435398 ! interaction with symbiont GO:0051702 5 5 0,000 0,03299564 0,16391098 ! cellular extravasation GO:0045123 5 5 0,000 0,03299564 0,16347036 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03299564 0,1630321 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03299564 0,16259618 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03299564 0,16216259 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03299564 0,16173131 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03299564 0,16130231 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03299564 0,16087559 ! response to amine stimulus GO:0014075 5 5 0,000 0,03299564 0,16045111 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03299564 0,16002887 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03299564 0,15960885 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03299564 0,15919103 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03299564 0,15877538 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03299564 0,15836191 ! neuron recognition GO:0008038 5 5 0,000 0,03299564 0,15795058 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03299564 0,15754138 ! decidualization GO:0046697 5 5 0,000 0,03299564 0,1571343 ! hair follicle maturation GO:0048820 5 5 0,000 0,03299564 0,15672931 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03299564 0,15632641 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03299564 0,15592557 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03299564 0,15552678 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03299564 0,15513003 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03299564 0,1547353 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03299564 0,15434257 ! postreplication repair GO:0006301 5 5 0,000 0,03299564 0,15395183 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03299564 0,15356306 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03299564 0,15317625 ! histone methylation GO:0016571 5 5 0,000 0,03299564 0,15279139 ! DNA methylation GO:0006306 5 5 0,000 0,03299564 0,15240845 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03299564 0,15202743 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03299564 0,15164831 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03299564 0,15127108 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03299564 0,15089571 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03299564 0,15052221 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03299564 0,15015055 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03299564 0,14978072 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03299564 0,14941271 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03299564 0,1490465 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03299564 0,14868208 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03299564 0,14831944 ! sterol catabolic process GO:0016127 5 5 0,000 0,03299564 0,14795857 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03299564 0,14759945 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03299564 0,14724206 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03299564 0,14688641 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03299564 0,14653246 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! zymogen activation GO:0031638 5 5 0,000 0,03299564 0,14618022 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03299564 0,14582967 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03299564 0,14548079 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03299564 0,14513359 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03299564 0,14478803 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03299564 0,14444411 ! nucleosome positioning GO:0016584 5 5 0,000 0,03299564 0,14410183 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03299564 0,14376116 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03299564 0,1434221 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03299564 0,14308464 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03299564 0,14274876 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03299564 0,14241445 ! NADPH regeneration GO:0006740 5 5 0,000 0,03299564 0,14208171 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03299564 0,14175052 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03299564 0,14142087 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03299564 0,14109274 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03299564 0,14076614 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03299564 0,14044104 ! sarcomere organization GO:0045214 5 5 0,000 0,03299564 0,14011745 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03299564 0,13979534 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03299564 0,13947471 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03299564 0,13915554 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03299564 0,13883784 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03299564 0,13852158 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03299564 0,13820675 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03299564 0,13789336 ! spleen development GO:0048536 5 5 0,000 0,03299564 0,13758139 ! male genitalia development GO:0030539 5 5 0,000 0,03299564 0,13727082 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03299564 0,13696165 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03299564 0,13665387 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03299564 0,13634747 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03299564 0,13604244 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03299564 0,13573878 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03299564 0,13543646 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03299564 0,13513549 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03299564 0,13483586 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03299564 0,13453755 ! ATP catabolic process GO:0006200 5 5 0,000 0,03299564 0,13424056 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03299564 0,13394487 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03299564 0,13365049 ! blastocyst formation GO:0001825 5 5 0,000 0,03299564 0,1333574 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03299564 0,13306558 ! embryonic gut development GO:0048566 5 5 0,000 0,03299564 0,13277505 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03299564 0,13248578 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03299564 0,13219777 ! activation of innate immune response GO:0002218 5 5 0,000 0,03299564 0,131911 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03299564 0,13162548 ! catecholamine transport GO:0051937 5 5 0,000 0,03299564 0,13134119 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03299564 0,13105813 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03299564 0,13077628 ! muscle adaptation GO:0043500 5 5 0,000 0,03299564 0,13049565 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03299564 0,13021621 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03299564 0,12993797 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03299564 0,12966092 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03299564 0,12938505 ! defense response to fungus GO:0050832 5 5 0,000 0,03299564 0,12911034 ! lysogeny GO:0030069 5 5 0,000 0,03299564 0,12883681 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03299564 0,12856442 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03299564 0,12829319 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03299564 0,1280231 ! response to nicotine GO:0035094 5 5 0,000 0,03299564 0,12775414 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03299564 0,12748631 ! mitochondrion localization GO:0051646 5 5 0,000 0,03299564 0,12721961 ! nucleus localization GO:0051647 5 5 0,000 0,03299564 0,12695401 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03299564 0,12668953 ! reproductive structure development GO:0048608 43 43 1,000 0,03319764 0,12720009 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,03319764 0,12693619 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03319764 0,12667338 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03463283 0,13187668 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,03609195 0,13714942 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,03609195 0,13686722 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,03609195 0,13658618 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,03757463 0,14190582 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,03757463 0,14161563 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,03757463 0,14132662 ! regulation of membrane potential GO:0042391 46 46 1,000 0,03757463 0,14103878 ! sex differentiation GO:0007548 47 47 1,000 0,0390805 0,14639299 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03946578 0,14753638 ! axon extension GO:0048675 7 6 0,000 0,03946578 0,14723773 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03946578 0,14694028 ! tRNA modification GO:0006400 6 6 0,000 0,03946578 0,14664403 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03946578 0,14634897 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03946578 0,14605509 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03946578 0,1457624 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03946578 0,14547087 ! regulation of S phase GO:0033261 6 6 0,000 0,03946578 0,14518051 ! myotube differentiation GO:0014902 6 6 0,000 0,03946578 0,14489131 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03946578 0,14460325 ! bone remodeling GO:0046849 6 6 0,000 0,03946578 0,14431634 ! N-glycan processing GO:0006491 6 6 0,000 0,03946578 0,14403057 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,03946578 0,14374592 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03946578 0,1434624 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03946578 0,14317999 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03946578 0,1428987 ! RNA methylation GO:0001510 6 6 0,000 0,03946578 0,1426185 ! cartilage condensation GO:0001502 7 6 0,000 0,03946578 0,14233941 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03946578 0,1420614 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03946578 0,14178448 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,03946578 0,14150863 ! artery development GO:0060840 6 6 0,000 0,03946578 0,14123386 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03946578 0,14096015 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03946578 0,1406875 ! androgen metabolic process GO:0008209 6 6 0,000 0,03946578 0,1404159 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03946578 0,14014535 ! limbic system development GO:0021761 7 6 0,000 0,03946578 0,13987584 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03946578 0,13960736 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03946578 0,13933992 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03946578 0,13907349 ! pathogenesis GO:0009405 6 6 0,000 0,03946578 0,13880809 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03946578 0,13854369 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03946578 0,1382803 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03946578 0,13801791 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03946578 0,13775651 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03946578 0,1374961 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03946578 0,13723667 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03946578 0,13697822 ! arginine metabolic process GO:0006525 6 6 0,000 0,03946578 0,13672075 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03946578 0,13646423 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03946578 0,13620868 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03946578 0,13595409 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03946578 0,13570044 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03946578 0,13544774 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03946578 0,13519598 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03946578 0,13494515 ! ER overload response GO:0006983 6 6 0,000 0,03946578 0,13469525 ! V(D)J recombination GO:0033151 6 6 0,000 0,03946578 0,13444628 ! focal adhesion formation GO:0048041 7 6 0,000 0,03946578 0,13419822 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03946578 0,13395108 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03946578 0,13370485 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03946578 0,13345952 ! regulation of heart rate GO:0002027 6 6 0,000 0,03946578 0,13321509 ! lipid digestion GO:0044241 6 6 0,000 0,03946578 0,13297155 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03946578 0,1327289 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03946578 0,13248713 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03946578 0,13224625 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03946578 0,13200624 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03946578 0,1317671 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03946578 0,13152882 ! ruffle organization GO:0031529 6 6 0,000 0,03946578 0,1312914 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,03946578 0,13105484 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03946578 0,13081913 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03946578 0,13058427 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03946578 0,13035025 ! L-amino acid transport GO:0015807 6 6 0,000 0,03946578 0,13011706 ! bone mineralization GO:0030282 6 6 0,000 0,03946578 0,12988471 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03946578 0,12965319 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03946578 0,12942249 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03946578 0,12919261 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,03946578 0,12896354 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03946578 0,12873529 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03946578 0,12850784 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03946578 0,12828119 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03946578 0,12805535 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03946578 0,12783029 ! regulation of organ growth GO:0046620 6 6 0,000 0,03946578 0,12760603 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03946578 0,12738255 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03946578 0,12715985 ! response to dsRNA GO:0043331 6 6 0,000 0,03946578 0,12693794 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03946578 0,12671679 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03946578 0,12649641 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03946578 0,1262768 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03946578 0,12605795 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03946578 0,12583986 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03946578 0,12562252 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03946578 0,12540593 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03946578 0,12519008 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03946578 0,12497498 ! erythrocyte development GO:0048821 6 6 0,000 0,03946578 0,12476061 ! renal water homeostasis GO:0003091 6 6 0,000 0,03946578 0,12454698 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03946578 0,12433408 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03946578 0,12412191 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03946578 0,12391045 ! ribosome assembly GO:0042255 6 6 0,000 0,03946578 0,12369972 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03946578 0,12348971 ! diencephalon development GO:0021536 6 6 0,000 0,03946578 0,1232804 ! fucose catabolic process GO:0019317 6 6 0,000 0,03946578 0,12307181 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03946578 0,12286391 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03946578 0,12265672 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03946578 0,12245023 ! regulation of cell division GO:0051302 6 6 0,000 0,03946578 0,12224443 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03946578 0,12203932 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03946578 0,1218349 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03946578 0,12163117 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03946578 0,12142811 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03946578 0,12122573 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03946578 0,12102402 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03946578 0,12082298 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03946578 0,12062262 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03946578 0,12042291 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03946578 0,12022386 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03946578 0,12002547 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03946578 0,11982774 ! thymus development GO:0048538 6 6 0,000 0,03946578 0,11963065 ! lymph node development GO:0048535 6 6 0,000 0,03946578 0,11943422 ! organic cation transport GO:0015695 6 6 0,000 0,03946578 0,11923842 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03946578 0,11904327 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03946578 0,11884875 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03946578 0,11865487 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03946578 0,11846162 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03946578 0,118269 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03946578 0,11807701 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03946578 0,11788564 ! alditol metabolic process GO:0019400 6 6 0,000 0,03946578 0,11769488 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03946578 0,11750474 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03946578 0,11731522 ! maternal placenta development GO:0001893 6 6 0,000 0,03946578 0,11712631 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03946578 0,116938 ! localization within membrane GO:0051668 6 6 0,000 0,03946578 0,1167503 ! ossification GO:0001503 50 49 1,000 0,04216036 0,12452169 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 1,000 0,04216036 0,12432246 ! negative regulation of transport GO:0051051 51 50 1,000 0,04373364 0,12875574 ! transcription initiation GO:0006352 50 50 1,000 0,04373364 0,12855039 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,04373364 0,12834569 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,04532868 0,13281521 GO:0051325|interphase, ! respiratory burst GO:0045730 7 7 0,000 0,04589356 0,13425689 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04589356 0,13404412 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04589356 0,13383202 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04589356 0,1336206 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04589356 0,13340984 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04589356 0,13319975 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04589356 0,13299031 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04589356 0,13278154 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04589356 0,13257342 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04589356 0,13236595 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04589356 0,13215912 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04589356 0,13195295 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04589356 0,13174741 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04589356 0,13154252 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04589356 0,13133826 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04589356 0,13113463 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04589356 0,13093164 ! axis specification GO:0009798 7 7 0,000 0,04589356 0,13072927 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04589356 0,13052753 ! visual behavior GO:0007632 7 7 0,000 0,04589356 0,13032641 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04589356 0,13012591 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04589356 0,12992602 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04589356 0,12972675 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04589356 0,12952808 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04589356 0,12933003 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04589356 0,12913258 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04589356 0,12893573 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04589356 0,12873948 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04589356 0,12854383 ! digestive system development GO:0055123 7 7 0,000 0,04589356 0,12834877 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04589356 0,1281543 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04589356 0,12796042 ! protein targeting to ER GO:0045047 8 7 0,000 0,04589356 0,12776713 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04589356 0,12757442 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04589356 0,12738229 ! endoderm development GO:0007492 7 7 0,000 0,04589356 0,12719074 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04589356 0,12699976 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04589356 0,12680935 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04589356 0,12661952 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04589356 0,12643025 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04589356 0,12624155 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04589356 0,12605341 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04589356 0,12586583 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04589356 0,12567881 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04589356 0,12549234 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04589356 0,12530643 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04589356 0,12512106 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04589356 0,12493625 ! response to X-ray GO:0010165 7 7 0,000 0,04589356 0,12475198 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04589356 0,12456825 ! UV protection GO:0009650 7 7 0,000 0,04589356 0,12438506 ! DNA integration GO:0015074 7 7 0,000 0,04589356 0,12420241 ! myofibril assembly GO:0030239 7 7 0,000 0,04589356 0,12402029 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04589356 0,12383871 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04589356 0,12365766 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04589356 0,12347714 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04589356 0,12329714 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04589356 0,12311767 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04589356 0,12293872 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04589356 0,12276029 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04589356 0,12258238 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04589356 0,12240498 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04589356 0,12222809 ! eating behavior GO:0042755 7 7 0,000 0,04589356 0,12205172 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04589356 0,12187585 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04589356 0,12170049 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04589356 0,12152563 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04589356 0,12135128 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04589356 0,12117742 ! cranial nerve development GO:0021545 7 7 0,000 0,04589356 0,12100406 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04589356 0,1208312 ! induction of an organ GO:0001759 7 7 0,000 0,04589356 0,12065883 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04589356 0,12048695 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04589356 0,12031556 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04589356 0,12014466 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04589356 0,11997424 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04589356 0,1198043 ! platelet activation GO:0030168 8 7 0,000 0,04589356 0,11963485 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04589356 0,11946587 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04589356 0,11929738 ! natural killer cell activation GO:0030101 7 7 0,000 0,04589356 0,11912935 ! response to gamma radiation GO:0010332 8 7 0,000 0,04589356 0,1189618 ! NADP metabolic process GO:0006739 7 7 0,000 0,04589356 0,11879472 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04589356 0,11862811 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04589356 0,11846196 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04589356 0,11829628 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04589356 0,11813106 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04589356 0,1179663 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04589356 0,117802 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04589356 0,11763816 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04589356 0,11747478 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04589356 0,11731184 ! cell-cell recognition GO:0009988 8 7 0,000 0,04589356 0,11714936 ! hormone catabolic process GO:0042447 7 7 0,000 0,04589356 0,11698733 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04589356 0,11682574 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04589356 0,11666461 ! oxygen transport GO:0015671 7 7 0,000 0,04589356 0,11650391 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04589356 0,11634366 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,04589356 0,11618385 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04589356 0,11602447 ! regulation of axon extension GO:0030516 7 7 0,000 0,04589356 0,11586553 ! cell killing GO:0001906 7 7 0,000 0,04589356 0,11570703 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04589356 0,11554896 ! adult feeding behavior GO:0008343 7 7 0,000 0,04589356 0,11539132 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04589356 0,11523411 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04589356 0,11507733 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04589356 0,11492098 ! response to cold GO:0009409 7 7 0,000 0,04589356 0,11476505 ! regulation of T cell activation GO:0050863 53 53 1,000 0,04858269 0,12132507 ! regulation of protein transport GO:0051223 53 53 1,000 0,04858269 0,12116089 GO:0070201|regulation of establishment of protein localization, ! hormone metabolic process GO:0042445 55 54 1,000 0,05024097 0,12512716 ! sulfur metabolic process GO:0006790 55 54 1,000 0,05024097 0,1249583 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,05024097 0,12478989 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05191964 0,12878586 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,05191964 0,12861276 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05227926 0,12932977 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05227926 0,12915641 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05227926 0,12898351 ! positive regulation of translation GO:0045727 8 8 0,000 0,05227926 0,12881107 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05227926 0,12863909 ! superoxide anion generation GO:0042554 8 8 0,000 0,05227926 0,12846757 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05227926 0,12829651 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05227926 0,1281259 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05227926 0,12795575 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05227926 0,12778605 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05227926 0,12761679 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05227926 0,12744799 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,05227926 0,12727963 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05227926 0,12711171 ! zinc ion transport GO:0006829 8 8 0,000 0,05227926 0,12694424 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05227926 0,12677721 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05227926 0,12661062 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05227926 0,12644446 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05227926 0,12627874 ! lipid localization GO:0010876 8 8 0,000 0,05227926 0,12611345 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05227926 0,1259486 ! response to cAMP GO:0051591 8 8 0,000 0,05227926 0,12578418 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05227926 0,12562018 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05227926 0,12545661 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05227926 0,12529347 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05227926 0,12513075 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05227926 0,12496846 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05227926 0,12480658 ! sensory perception of taste GO:0050909 8 8 0,000 0,05227926 0,12464512 ! organelle fusion GO:0048284 8 8 0,000 0,05227926 0,12448408 ! pancreas development GO:0031016 8 8 0,000 0,05227926 0,12432346 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05227926 0,12416325 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05227926 0,12400345 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05227926 0,12384406 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05227926 0,12368508 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05227926 0,12352651 ! sperm motility GO:0030317 8 8 0,000 0,05227926 0,12336835 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05227926 0,12321059 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05227926 0,12305323 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05227926 0,12289627 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05227926 0,12273972 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05227926 0,12258356 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05227926 0,1224278 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05227926 0,12227244 ! Golgi organization GO:0007030 8 8 0,000 0,05227926 0,12211746 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05227926 0,12196288 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05227926 0,1218087 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,05227926 0,1216549 ! fructose metabolic process GO:0006000 8 8 0,000 0,05227926 0,12150149 ! mannose metabolic process GO:0006013 9 8 0,000 0,05227926 0,12134846 ! NAD metabolic process GO:0019674 8 8 0,000 0,05227926 0,12119582 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05227926 0,12104357 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05227926 0,12089169 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,05227926 0,1207402 ! response to fungus GO:0009620 8 8 0,000 0,05227926 0,12058909 ! stem cell differentiation GO:0048863 8 8 0,000 0,05227926 0,12043835 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05227926 0,12028799 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05227926 0,120138 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05227926 0,11998839 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05227926 0,11983915 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05227926 0,11969028 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05227926 0,11954179 ! vasoconstriction GO:0042310 8 8 0,000 0,05227926 0,11939365 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05227926 0,11924589 ! muscle cell development GO:0055001 8 8 0,000 0,05227926 0,11909849 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05227926 0,11895146 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05227926 0,11880478 ! sensory perception of pain GO:0019233 8 8 0,000 0,05227926 0,11865847 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05227926 0,11851252 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05227926 0,11836693 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05227926 0,11822169 ! chromatin silencing GO:0006342 8 8 0,000 0,05227926 0,11807681 ! tissue regeneration GO:0042246 8 8 0,000 0,05227926 0,11793229 ! salivary gland development GO:0007431 8 8 0,000 0,05227926 0,11778812 ! T cell homeostasis GO:0043029 8 8 0,000 0,05227926 0,1176443 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05227926 0,11750083 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,05227926 0,11735771 ! water homeostasis GO:0030104 8 8 0,000 0,05227926 0,11721494 ! cofactor transport GO:0051181 8 8 0,000 0,05227926 0,11707251 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05227926 0,11693044 ! acid secretion GO:0046717 8 8 0,000 0,05227926 0,1167887 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,05227926 0,11664731 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05227926 0,11650626 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05227926 0,11636555 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05227926 0,11622519 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05227926 0,11608516 ! regulation of RNA stability GO:0043487 8 8 0,000 0,05227926 0,11594546 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05227926 0,1158061 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05227926 0,11566708 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,05227926 0,11552839 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05227926 0,11539003 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05227926 0,11525201 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05227926 0,11511431 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05227926 0,11497694 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05227926 0,1148399 ! developmental induction GO:0031128 8 8 0,000 0,05227926 0,11470319 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05227926 0,1145668 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05227926 0,11443074 ! actin filament polymerization GO:0030041 9 8 0,000 0,05227926 0,11429499 ! peptide hormone processing GO:0016486 8 8 0,000 0,05227926 0,11415957 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05227926 0,11402447 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05227926 0,11388969 ! extracellular structure organization GO:0043062 56 56 1,000 0,05361837 0,11666902 ! regulation of protein localization GO:0032880 58 57 1,000 0,05533684 0,12026627 ! lactation GO:0007595 10 9 0,000 0,05862314 0,12725848 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05862314 0,12710877 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05862314 0,1269594 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,05862314 0,12681039 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05862314 0,12666173 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05862314 0,12651341 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05862314 0,12636544 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,05862314 0,12621782 ! viral genome replication GO:0019079 9 9 0,000 0,05862314 0,12607054 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05862314 0,1259236 ! copper ion transport GO:0006825 9 9 0,000 0,05862314 0,12577701 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05862314 0,12563076 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05862314 0,12548485 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05862314 0,12533927 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05862314 0,12519404 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05862314 0,12504914 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05862314 0,12490457 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05862314 0,12476034 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05862314 0,12461644 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05862314 0,12447287 ! phospholipid efflux GO:0033700 9 9 0,000 0,05862314 0,12432963 ! response to alkaloid GO:0043279 10 9 0,000 0,05862314 0,12418673 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05862314 0,12404415 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05862314 0,1239019 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,05862314 0,12375997 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05862314 0,12361837 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05862314 0,12347709 ! response to ethanol GO:0045471 9 9 0,000 0,05862314 0,12333613 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,05862314 0,1231955 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05862314 0,12305519 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05862314 0,12291519 ! methionine metabolic process GO:0006555 9 9 0,000 0,05862314 0,12277551 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05862314 0,12263616 ! cerebral cortex development GO:0021987 9 9 0,000 0,05862314 0,12249711 ! response to osmotic stress GO:0006970 9 9 0,000 0,05862314 0,12235838 ! pigmentation during development GO:0048066 9 9 0,000 0,05862314 0,12221997 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05862314 0,12208187 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05862314 0,12194408 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05862314 0,1218066 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05862314 0,12166943 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05862314 0,12153257 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05862314 0,12139601 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05862314 0,12125977 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,05862314 0,12112383 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,05862314 0,12098819 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05862314 0,12085286 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05862314 0,12071782 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05862314 0,12058309 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05862314 0,12044867 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05862314 0,12031454 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05862314 0,1201807 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05862314 0,12004717 ! DNA replication initiation GO:0006270 9 9 0,000 0,05862314 0,11991393 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05862314 0,11978099 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05862314 0,11964834 ! regulation of cellular pH GO:0030641 9 9 0,000 0,05862314 0,11951599 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05862314 0,11938393 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05862314 0,11925216 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05862314 0,11912068 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05862314 0,11898949 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05862314 0,11885858 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05862314 0,11872797 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,05862314 0,11859764 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05862314 0,1184676 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,05862314 0,11833785 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05862314 0,11820837 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05862314 0,11807918 ! purine base metabolic process GO:0006144 9 9 0,000 0,05862314 0,11795028 ! gas transport GO:0015669 9 9 0,000 0,05862314 0,11782165 ! cholesterol efflux GO:0033344 9 9 0,000 0,05862314 0,1176933 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05862314 0,11756524 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05862314 0,11743745 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05862314 0,11730994 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05862314 0,1171827 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,05862314 0,11705575 ! defense response to virus GO:0051607 9 9 0,000 0,05862314 0,11692906 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05862314 0,11680265 ! actin filament-based movement GO:0030048 9 9 0,000 0,05862314 0,11667651 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05862314 0,11655065 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,0606074 0,12036578 ! axonogenesis GO:0007409 66 62 1,000 0,06421388 0,12739093 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,06421388 0,12725395 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06492548 0,12852594 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06492548 0,12838804 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06492548 0,12825043 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06492548 0,12811312 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06492548 0,1279761 ! neuron maturation GO:0042551 10 10 0,000 0,06492548 0,12783937 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06492548 0,12770294 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06492548 0,1275668 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06492548 0,12743094 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06492548 0,12729538 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06492548 0,1271601 ! hormone secretion GO:0046879 10 10 0,000 0,06492548 0,12702511 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06492548 0,12689041 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06492548 0,12675599 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,06492548 0,12662186 ! inositol metabolic process GO:0006020 10 10 0,000 0,06492548 0,12648801 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06492548 0,12635444 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06492548 0,12622115 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06492548 0,12608815 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06492548 0,12595543 ! glial cell development GO:0021782 10 10 0,000 0,06492548 0,12582298 ! phototransduction GO:0007602 11 10 0,000 0,06492548 0,12569081 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,06492548 0,12555892 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06492548 0,12542731 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,06492548 0,12529597 ! fat cell differentiation GO:0045444 10 10 0,000 0,06492548 0,12516491 ! myoblast differentiation GO:0045445 10 10 0,000 0,06492548 0,12503412 ! centrosome cycle GO:0007098 10 10 0,000 0,06492548 0,12490361 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06492548 0,12477336 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06492548 0,12464339 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06492548 0,12451369 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06492548 0,12438426 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06492548 0,12425509 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06492548 0,1241262 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06492548 0,12399757 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06492548 0,12386921 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06492548 0,12374111 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,06492548 0,12361328 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06492548 0,12348571 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06492548 0,12335841 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06492548 0,12323136 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06492548 0,12310458 ! exocrine system development GO:0035272 10 10 0,000 0,06492548 0,12297806 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06492548 0,1228518 ! embryo implantation GO:0007566 11 10 0,000 0,06492548 0,1227258 ! regulation of protein binding GO:0043393 11 10 0,000 0,06492548 0,12260006 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06492548 0,12247457 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06492548 0,12234934 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06492548 0,12222437 ! protein export from nucleus GO:0006611 10 10 0,000 0,06492548 0,12209965 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06492548 0,12197518 ! cytolysis GO:0019835 10 10 0,000 0,06492548 0,12185097 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06492548 0,12172701 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06492548 0,12160331 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06492548 0,12147985 ! histone deacetylation GO:0016575 10 10 0,000 0,06492548 0,12135665 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06492548 0,12123369 ! gland morphogenesis GO:0022612 10 10 0,000 0,06492548 0,12111099 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06492548 0,12098853 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06492548 0,12086632 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06492548 0,12074435 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06492548 0,12062263 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06492548 0,12050116 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06492548 0,12037993 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06492548 0,12025895 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06492548 0,12013821 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06492548 0,12001771 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06492548 0,11989745 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06492548 0,11977743 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06492548 0,11965765 ! nerve development GO:0021675 10 10 0,000 0,06492548 0,11953812 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06492548 0,11941882 ! gut development GO:0048565 10 10 0,000 0,06492548 0,11929975 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06492548 0,11918093 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,06492548 0,11906234 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,06492548 0,11894399 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06492548 0,11882587 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06492548 0,11870799 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,066044 0,1206334 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,06789164 0,12388544 ! angiogenesis GO:0001525 65 64 1,000 0,06789164 0,12376291 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,06789164 0,12364061 ! anion transport GO:0006820 65 65 1,000 0,06975649 0,12691137 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,06975649 0,12678621 ! regulation of hormone levels GO:0010817 66 65 1,000 0,06975649 0,1266613 ! protein secretion GO:0009306 11 11 0,000 0,07118653 0,12913068 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07118653 0,12900371 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07118653 0,12887699 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07118653 0,12875051 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07118653 0,12862429 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07118653 0,12849831 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07118653 0,12837258 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07118653 0,12824709 ! skin development GO:0043588 11 11 0,000 0,07118653 0,12812185 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07118653 0,12799685 ! endothelial cell migration GO:0043542 11 11 0,000 0,07118653 0,1278721 ! peroxisomal transport GO:0043574 11 11 0,000 0,07118653 0,12774759 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07118653 0,12762332 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,07118653 0,12749929 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07118653 0,12737551 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07118653 0,12725196 ! T cell proliferation GO:0042098 11 11 0,000 0,07118653 0,12712866 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07118653 0,12700559 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07118653 0,12688276 ! spinal cord development GO:0021510 11 11 0,000 0,07118653 0,12676017 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07118653 0,12663781 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07118653 0,12651569 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07118653 0,12639381 ! digestive system process GO:0022600 11 11 0,000 0,07118653 0,12627216 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07118653 0,12615074 ! fucose metabolic process GO:0006004 11 11 0,000 0,07118653 0,12602956 ! membrane budding GO:0006900 11 11 0,000 0,07118653 0,12590861 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,07118653 0,12578789 ! monoamine transport GO:0015844 11 11 0,000 0,07118653 0,12566741 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07118653 0,12554715 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07118653 0,12542713 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07118653 0,12530733 ! body fluid secretion GO:0007589 11 11 0,000 0,07118653 0,12518776 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,07118653 0,12506842 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07118653 0,12494931 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07118653 0,12483042 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,07118653 0,12471176 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07118653 0,12459333 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07118653 0,12447512 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,07118653 0,12435713 ! oogenesis GO:0048477 11 11 0,000 0,07118653 0,12423937 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07118653 0,12412183 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07118653 0,12400451 ! vitamin transport GO:0051180 11 11 0,000 0,07118653 0,12388742 ! muscle maintenance GO:0046716 12 11 0,000 0,07118653 0,12377054 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07118653 0,12365389 ! hindbrain development GO:0030902 11 11 0,000 0,07118653 0,12353745 ! steroid catabolic process GO:0006706 11 11 0,000 0,07118653 0,12342124 ! endocrine process GO:0050886 11 11 0,000 0,07118653 0,12330524 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07118653 0,12318946 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07118653 0,1230739 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07118653 0,12295855 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07118653 0,12284342 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,07353663 0,12678018 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of cell size GO:0008361 68 68 1,000 0,07545132 0,12995961 ! regulation of translation GO:0006417 69 69 1,000 0,07738204 0,13316069 ! regionalization GO:0003002 70 69 1,000 0,07738204 0,13303647 ! response to nutrient levels GO:0031667 69 69 1,000 0,07738204 0,13291249 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,07738204 0,13278873 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,07740656 0,13270725 ! translational initiation GO:0006413 12 12 0,000 0,07740656 0,13258392 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,07740656 0,13246081 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07740656 0,13233794 ! initiation of viral infection GO:0019059 12 12 0,000 0,07740656 0,13221529 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07740656 0,13209287 ! iron ion transport GO:0006826 13 12 0,000 0,07740656 0,13197067 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07740656 0,1318487 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07740656 0,13172696 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07740656 0,13160544 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07740656 0,13148414 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07740656 0,13136307 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,07740656 0,13124222 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,07740656 0,1311216 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,07740656 0,13100119 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07740656 0,13088101 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07740656 0,13076104 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07740656 0,1306413 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,07740656 0,13052177 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,07740656 0,13040247 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,07740656 0,13028338 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07740656 0,1301645 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07740656 0,13004585 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,07740656 0,12992741 ! acute-phase response GO:0006953 12 12 0,000 0,07740656 0,12980919 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07740656 0,12969118 ! vacuolar transport GO:0007034 12 12 0,000 0,07740656 0,12957339 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07740656 0,12945581 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07740656 0,12933844 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07740656 0,12922128 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07740656 0,12910434 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,07740656 0,12898761 ! male gonad development GO:0008584 12 12 0,000 0,07740656 0,12887109 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07740656 0,12875478 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,07740656 0,12863868 ! renal system process GO:0003014 12 12 0,000 0,07740656 0,12852279 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07740656 0,12840711 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07740656 0,12829163 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,07740656 0,12817637 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07740656 0,12806131 ! pallium development GO:0021543 13 12 0,000 0,07740656 0,12794645 ! cell fate determination GO:0001709 12 12 0,000 0,07740656 0,12783181 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,07740656 0,12771737 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,07740656 0,12760313 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07740656 0,12748909 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07740656 0,12737527 ! detection of light stimulus GO:0009583 13 12 0,000 0,07740656 0,12726164 ! synaptogenesis GO:0007416 12 12 0,000 0,07740656 0,12714822 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07740656 0,12703499 ! hormone transport GO:0009914 12 12 0,000 0,07740656 0,12692197 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07740656 0,12680915 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07740656 0,12669653 ! spermatid differentiation GO:0048515 13 12 0,000 0,07740656 0,12658411 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,07740656 0,12647189 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07740656 0,12635987 ! neural tube closure GO:0001843 13 12 0,000 0,07740656 0,12624805 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,07740656 0,12613643 ! cell part morphogenesis GO:0032990 75 70 1,000 0,07932849 0,12915407 ! growth GO:0040007 70 70 1,000 0,07932849 0,12904008 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,0812904 0,13211482 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,0812904 0,13199842 ! regulation of cell activation GO:0050865 71 71 1,000 0,0812904 0,13188222 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,08326747 0,13497093 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,08358584 0,13536794 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08358584 0,13524909 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08358584 0,13513045 ! phenol metabolic process GO:0018958 13 13 0,000 0,08358584 0,13501202 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,08358584 0,13489379 ! gluconeogenesis GO:0006094 13 13 0,000 0,08358584 0,13477578 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08358584 0,13465796 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08358584 0,13454036 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08358584 0,13442296 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08358584 0,13430576 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08358584 0,13418877 ! regeneration GO:0031099 13 13 0,000 0,08358584 0,13407199 ! keratinization GO:0031424 13 13 0,000 0,08358584 0,1339554 ! post-embryonic development GO:0009791 14 13 0,000 0,08358584 0,13383902 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08358584 0,13372284 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08358584 0,13360686 ! vasculogenesis GO:0001570 13 13 0,000 0,08358584 0,13349108 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08358584 0,13337551 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08358584 0,13326013 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,08358584 0,13314495 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,08358584 0,13302998 GO:0051384|response to glucocorticoid stimulus, ! autophagy GO:0006914 13 13 0,000 0,08358584 0,1329152 ! ureteric bud development GO:0001657 13 13 0,000 0,08358584 0,13280061 ! cell aging GO:0007569 13 13 0,000 0,08358584 0,13268623 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,08358584 0,13257204 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,08358584 0,13245805 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,08358584 0,13234425 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08358584 0,13223065 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08358584 0,13211725 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08358584 0,13200404 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08358584 0,13189102 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,08358584 0,1317782 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08358584 0,13166557 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08358584 0,13155313 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08358584 0,13144088 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08358584 0,13132882 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08358584 0,13121696 ! vasodilation GO:0042311 14 13 0,000 0,08358584 0,13110529 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08358584 0,1309938 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08358584 0,13088251 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08358584 0,1307714 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,08358584 0,13066048 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,08358584 0,13054976 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08358584 0,13043921 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08358584 0,13032886 ! immunoglobulin production GO:0002377 13 13 0,000 0,08358584 0,13021869 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08358584 0,13010871 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,08358584 0,12999891 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08358584 0,1298893 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,08358584 0,12977987 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08358584 0,12967063 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08358584 0,12956157 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08358584 0,1294527 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08358584 0,12934401 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08358584 0,1292355 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08358584 0,12912717 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08358584 0,12901902 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08358584 0,12891106 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08358584 0,12880327 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08358584 0,12869567 ! blastocyst development GO:0001824 13 13 0,000 0,08358584 0,12858824 ! telomere organization GO:0032200 13 13 0,000 0,08358584 0,12848099 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08358584 0,12837393 ! regulation of amine transport GO:0051952 13 13 0,000 0,08358584 0,12826704 ! tissue homeostasis GO:0001894 13 13 0,000 0,08358584 0,12816033 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08358584 0,12805379 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,087266 0,13358077 ! neuron fate commitment GO:0048663 14 14 0,000 0,08972463 0,13723029 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08972463 0,1371165 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08972463 0,1370029 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08972463 0,13688948 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08972463 0,13677626 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08972463 0,13666322 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08972463 0,13655037 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08972463 0,1364377 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,08972463 0,13632522 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08972463 0,13621293 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08972463 0,13610082 ! vesicle docking GO:0048278 14 14 0,000 0,08972463 0,13598889 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08972463 0,13587715 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08972463 0,1357656 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08972463 0,13565422 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08972463 0,13554303 ! hair cycle GO:0042633 14 14 0,000 0,08972463 0,13543202 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08972463 0,13532119 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08972463 0,13521054 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,08972463 0,13510008 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08972463 0,13498979 ! lysosome organization GO:0007040 14 14 0,000 0,08972463 0,13487969 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08972463 0,13476976 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08972463 0,13466001 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,08972463 0,13455044 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,08972463 0,13444105 ! primary neural tube formation GO:0014020 15 14 0,000 0,08972463 0,13433184 ! peptide cross-linking GO:0018149 14 14 0,000 0,08972463 0,13422281 ! regulation of behavior GO:0050795 14 14 0,000 0,08972463 0,13411395 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08972463 0,13400526 ! base-excision repair GO:0006284 14 14 0,000 0,08972463 0,13389676 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08972463 0,13378843 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08972463 0,13368027 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08972463 0,13357229 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08972463 0,13346448 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08972463 0,13335685 ! collagen fibril organization GO:0030199 14 14 0,000 0,08972463 0,13324939 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08972463 0,13314211 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08972463 0,13303499 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08972463 0,13292805 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08972463 0,13282128 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08972463 0,13271468 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08972463 0,13260826 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,08972463 0,132502 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08972463 0,13239591 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,09132189 0,134645 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,09337066 0,13755566 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,09337066 0,13744579 ! microtubule-based movement GO:0007018 82 78 1,000 0,09543297 0,14036948 ! metal ion homeostasis GO:0055065 78 78 1,000 0,09543297 0,14025755 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,09582318 0,14071883 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,09582318 0,14060679 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09582318 0,14049493 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09582318 0,14038325 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,09582318 0,14027175 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09582318 0,14016042 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09582318 0,14004927 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09582318 0,1399383 ! response to vitamin GO:0033273 15 15 0,000 0,09582318 0,1398275 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,09582318 0,13971687 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,09582318 0,13960643 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09582318 0,13949615 ! ovarian follicle development GO:0001541 15 15 0,000 0,09582318 0,13938605 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09582318 0,13927613 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09582318 0,13916637 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09582318 0,13905679 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09582318 0,13894739 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,09582318 0,13883815 ! heme metabolic process GO:0042168 15 15 0,000 0,09582318 0,13872909 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09582318 0,1386202 ! chromosome condensation GO:0030261 15 15 0,000 0,09582318 0,13851147 ! response to ionizing radiation GO:0010212 16 15 0,000 0,09582318 0,13840292 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09582318 0,13829454 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09582318 0,13818633 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09582318 0,13807829 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09582318 0,13797041 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09582318 0,13786271 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09582318 0,13775517 ! phospholipid transport GO:0015914 15 15 0,000 0,09582318 0,1376478 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,09582318 0,1375406 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09582318 0,13743356 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09582318 0,13732669 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,09582318 0,13721999 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,09582318 0,13711345 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09582318 0,13700708 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09582318 0,13690088 ! protein homooligomerization GO:0051260 15 15 0,000 0,09582318 0,13679483 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09582318 0,13668895 ! neuron projection development GO:0031175 85 80 1,000 0,09959713 0,1419625 ! MAPKKK cascade GO:0000165 82 81 1,000 0,10169847 0,14484566 ! tube development GO:0035295 83 81 1,000 0,10169847 0,14473381 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,10188176 0,14488278 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10188176 0,14477108 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,10188176 0,14465954 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10188176 0,14454818 ! learning GO:0007612 16 16 0,000 0,10188176 0,14443699 ! circadian rhythm GO:0007623 16 16 0,000 0,10188176 0,14432597 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10188176 0,14421512 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,10188176 0,14410444 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,10188176 0,14399393 ! vacuole organization GO:0007033 16 16 0,000 0,10188176 0,14388359 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,10188176 0,14377342 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10188176 0,14366342 ! vesicle targeting GO:0006903 17 16 0,000 0,10188176 0,14355358 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10188176 0,14344392 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,10188176 0,14333442 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10188176 0,14322509 ! positive regulation of cell development GO:0010720 16 16 0,000 0,10188176 0,14311592 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,10188176 0,14300692 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,10188176 0,14289809 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,10188176 0,14278942 ! cell fate specification GO:0001708 16 16 0,000 0,10188176 0,14268092 ! pentose metabolic process GO:0019321 16 16 0,000 0,10188176 0,14257258 ! fatty acid transport GO:0015908 16 16 0,000 0,10188176 0,14246441 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10188176 0,1423564 ! cofactor catabolic process GO:0051187 16 16 0,000 0,10188176 0,14224855 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10188176 0,14214087 ! polyol metabolic process GO:0019751 16 16 0,000 0,10188176 0,14203335 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10188176 0,14192599 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10188176 0,1418188 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10188176 0,14171176 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10188176 0,14160489 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,10188176 0,14149818 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,10188176 0,14139163 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,10188176 0,14128524 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,10593839 0,14680034 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,10790062 0,14940709 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,10790062 0,14929493 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,10790062 0,14918293 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10790062 0,1490711 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,10790062 0,14895943 ! sensory perception of smell GO:0007608 17 17 0,000 0,10790062 0,14884794 ! glucose transport GO:0015758 17 17 0,000 0,10790062 0,14873661 ! tissue remodeling GO:0048771 17 17 0,000 0,10790062 0,14862544 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10790062 0,14851445 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,10790062 0,14840361 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,10790062 0,14829295 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10790062 0,14818245 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10790062 0,14807211 ! neural crest cell development GO:0014032 19 17 0,000 0,10790062 0,14796194 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,10790062 0,14785193 ! negative regulation of cell development GO:0010721 18 17 0,000 0,10790062 0,14774208 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,10790062 0,1476324 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,10790062 0,14752288 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,10790062 0,14741352 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,10790062 0,14730433 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,10790062 0,14719529 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,10790062 0,14708642 ! pigmentation GO:0043473 17 17 0,000 0,10790062 0,14697771 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,10790062 0,14686916 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10790062 0,14676077 ! embryonic organ development GO:0048568 17 17 0,000 0,10790062 0,14665254 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,10790062 0,14654447 ! liver development GO:0001889 17 17 0,000 0,10790062 0,14643656 ! gene silencing GO:0016458 17 17 0,000 0,10790062 0,1463288 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,10807646 0,1464595 ! regulation of cellular localization GO:0060341 86 85 1,000 0,11022629 0,14926308 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11388001 0,15409755 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,11388001 0,15398449 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11388001 0,1538716 ! meiosis I GO:0007127 18 18 0,000 0,11388001 0,15375887 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,11388001 0,15364631 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11388001 0,15353392 ! membrane docking GO:0022406 18 18 0,000 0,11388001 0,15342168 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,11388001 0,15330961 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,11388001 0,15319771 GO:0070661|leukocyte proliferation, ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11388001 0,15308597 ! hexose transport GO:0008645 18 18 0,000 0,11388001 0,15297439 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,11388001 0,15286297 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,11388001 0,15275172 ! striated muscle contraction GO:0006941 18 18 0,000 0,11388001 0,15264063 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,11388001 0,1525297 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,11388001 0,15241893 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,11388001 0,15230832 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,11388001 0,15219787 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11388001 0,15208758 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,11388001 0,15197745 ! B cell differentiation GO:0030183 18 18 0,000 0,11388001 0,15186748 ! BMP signaling pathway GO:0030509 18 18 0,000 0,11388001 0,15175767 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,11388001 0,15164802 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,11893828 0,15826949 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,11982019 0,15932801 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11982019 0,15921313 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11982019 0,15909843 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,11982019 0,15898388 ! regulation of pH GO:0006885 19 19 0,000 0,11982019 0,15886951 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,11982019 0,1587553 ! feeding behavior GO:0007631 19 19 0,000 0,11982019 0,15864125 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,11982019 0,15852736 ! peroxisome organization GO:0007031 19 19 0,000 0,11982019 0,15841364 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,11982019 0,15830008 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11982019 0,15818669 ! metanephros development GO:0001656 19 19 0,000 0,11982019 0,15807345 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11982019 0,15796038 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,11982019 0,15784747 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11982019 0,15773473 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,11982019 0,15762214 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11982019 0,15750971 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11982019 0,15739745 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,11982019 0,15728534 ! eye morphogenesis GO:0048592 19 19 0,000 0,11982019 0,15717339 ! regulation of cell shape GO:0008360 21 19 0,000 0,11982019 0,1570616 ! placenta development GO:0001890 19 19 0,000 0,11982019 0,15694998 ! response to heat GO:0009408 19 19 0,000 0,11982019 0,15683851 ! vesicle localization GO:0051648 20 19 0,000 0,11982019 0,15672719 ! brain development GO:0007420 91 90 1,000 0,12114325 0,1583454 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,12335855 0,16112673 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,12335855 0,16101261 ! regulation of muscle development GO:0048634 21 20 0,000 0,12572141 0,16398058 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,12572141 0,16386461 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,12572141 0,16374881 ! organic ether metabolic process GO:0018904 20 20 0,000 0,12572141 0,16363317 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,12572141 0,16351769 ! nucleus organization GO:0006997 20 20 0,000 0,12572141 0,16340237 ! phagocytosis GO:0006909 21 20 0,000 0,12572141 0,16328722 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,12572141 0,16317223 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,12572141 0,1630574 ! protein targeting to membrane GO:0006612 22 20 0,000 0,12572141 0,16294273 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,12572141 0,16282823 ! chromatin remodeling GO:0006338 20 20 0,000 0,12572141 0,16271388 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,12572141 0,16259969 ! lipid oxidation GO:0034440 20 20 0,000 0,12572141 0,16248567 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,12572141 0,1623718 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,12572141 0,1622581 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,12572141 0,16214455 ! RNA modification GO:0009451 20 20 0,000 0,12572141 0,16203116 ! single fertilization GO:0007338 21 20 0,000 0,12572141 0,16191793 ! regulation of B cell activation GO:0050864 20 20 0,000 0,12572141 0,16180486 ! regulation of response to stress GO:0080134 97 94 1,000 0,13006414 0,16727718 ! blood vessel development GO:0001568 95 94 1,000 0,13006414 0,16716053 ! pattern specification process GO:0007389 96 94 1,000 0,13006414 0,16704404 ! epidermis development GO:0008544 94 94 1,000 0,13006414 0,16692772 ! cofactor metabolic process GO:0051186 95 94 1,000 0,13006414 0,16681155 ! mRNA catabolic process GO:0006402 21 21 0,000 0,13158392 0,16864337 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,13158392 0,16852618 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,13158392 0,16840915 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,13158392 0,16829228 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,13158392 0,16817557 ! Notch signaling pathway GO:0007219 22 21 0,000 0,13158392 0,16805902 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,13158392 0,16794264 ! ear morphogenesis GO:0042471 21 21 0,000 0,13158392 0,16782641 ! organic anion transport GO:0015711 21 21 0,000 0,13158392 0,16771035 ! cholesterol transport GO:0030301 21 21 0,000 0,13158392 0,16759445 GO:0015918|sterol transport, ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,13158392 0,16747871 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,13158392 0,16736313 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,13158392 0,1672477 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,13158392 0,16713244 ! regulation of proteolysis GO:0030162 21 21 0,000 0,13158392 0,16701733 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,13158392 0,16690239 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,13158392 0,1667876 ! regulation of cell growth GO:0001558 97 96 1,000 0,13458203 0,17047057 ! vasculature development GO:0001944 97 96 1,000 0,13458203 0,17035349 ! RNA export from nucleus GO:0006405 22 22 0,000 0,13740797 0,17381118 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,13740797 0,17369197 ! regulation of ion transport GO:0043269 22 22 0,000 0,13740797 0,17357292 ! odontogenesis GO:0042476 22 22 0,000 0,13740797 0,17345403 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,13740797 0,17333531 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,13740797 0,17321675 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,13740797 0,17309835 ! ovulation cycle process GO:0022602 22 22 0,000 0,13740797 0,17298011 ! spindle organization GO:0007051 22 22 0,000 0,13740797 0,17286204 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,13740797 0,17274413 ! cell chemotaxis GO:0060326 23 22 0,000 0,13740797 0,17262637 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,13740797 0,17250878 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,13740797 0,17239135 ! male sex differentiation GO:0046661 22 22 0,000 0,13740797 0,17227407 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,13740797 0,17215696 ! biopolymer methylation GO:0043414 22 22 0,000 0,13740797 0,17204001 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,13740797 0,17192321 ! detection of external stimulus GO:0009581 23 22 0,000 0,13740797 0,17180657 ! neuron migration GO:0001764 22 22 0,000 0,13740797 0,17169009 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,13740797 0,17157377 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,13740797 0,17145761 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,13740797 0,1713416 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,13740797 0,17122575 ! aerobic respiration GO:0009060 22 22 0,000 0,13740797 0,17111006 ! cytokine production GO:0001816 22 22 0,000 0,13740797 0,17099452 ! cytokinesis GO:0000910 23 22 0,000 0,13740797 0,17087914 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,13740797 0,17076392 ! anti-apoptosis GO:0006916 100 99 1,000 0,14142578 0,17563862 ! ectoderm development GO:0007398 99 99 1,000 0,14142578 0,17552035 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,1431938 0,177595 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,1431938 0,17747557 ! viral infectious cycle GO:0019058 23 23 0,000 0,1431938 0,1773563 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,1431938 0,17723719 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,1431938 0,17711824 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,1431938 0,17699945 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,1431938 0,17688081 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,1431938 0,17676234 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,1431938 0,17664403 ! endocrine system development GO:0035270 23 23 0,000 0,1431938 0,17652587 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,1431938 0,17640787 ! female gonad development GO:0008585 23 23 0,000 0,1431938 0,17629003 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,1431938 0,17617235 ! lipid homeostasis GO:0055088 23 23 0,000 0,1431938 0,17605482 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,1431938 0,17593745 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,1431938 0,17582024 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,1431938 0,17570318 ! response to hormone stimulus GO:0009725 102 100 1,000 0,14372402 0,17623644 ! mitochondrial transport GO:0006839 24 24 0,000 0,14894166 0,18251296 ! gliogenesis GO:0042063 24 24 0,000 0,14894166 0,18239168 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,14894166 0,18227057 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,14894166 0,18214962 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,14894166 0,18202884 ! T cell differentiation GO:0030217 24 24 0,000 0,14894166 0,18190821 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,14894166 0,18178774 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,14894166 0,18166743 ! ovulation cycle GO:0042698 24 24 0,000 0,14894166 0,18154728 ! fertilization GO:0009566 25 24 0,000 0,14894166 0,18142729 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,14894166 0,18130745 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,14894166 0,18118778 ! glucan metabolic process GO:0044042 25 24 0,000 0,14894166 0,18106826 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,1546518 0,18788613 ! negative regulation of secretion GO:0051048 26 25 0,000 0,1546518 0,18776236 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,1546518 0,18763875 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,1546518 0,1875153 ! cellular component disassembly GO:0022411 26 25 0,000 0,1546518 0,18739202 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,1546518 0,1872689 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,1546518 0,18714594 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,1546518 0,18702314 ! excretion GO:0007588 25 25 0,000 0,1546518 0,1869005 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,1546518 0,18677802 ! gastrulation GO:0007369 25 25 0,000 0,1546518 0,18665571 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,1546518 0,18653355 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,1546518 0,18641155 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,1546518 0,18628971 ! positive regulation of defense response GO:0031349 26 26 0,000 0,16032445 0,19299671 ! glycolysis GO:0006096 26 26 0,000 0,16032445 0,19287073 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,16032445 0,19274492 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,16032445 0,19261927 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,16032445 0,19249378 ! cellular defense response GO:0006968 26 26 0,000 0,16032445 0,19236846 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,16032445 0,1922433 ! double-strand break repair GO:0006302 27 26 0,000 0,16032445 0,19211831 ! regulation of protein secretion GO:0050708 26 26 0,000 0,16032445 0,19199347 ! germ cell development GO:0007281 27 26 0,000 0,16032445 0,1918688 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,16032445 0,19174429 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,16032445 0,19161995 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,16595985 0,19822684 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,16595985 0,19809845 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,16595985 0,19797023 ! activation of caspase activity GO:0006919 27 27 0,000 0,16595985 0,19784218 ! mesenchymal cell development GO:0014031 29 27 0,000 0,16595985 0,19771429 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,16595985 0,19758657 ! defense response to bacterium GO:0042742 27 27 0,000 0,16595985 0,19745901 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,16595985 0,19733162 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,16595985 0,19720439 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,17155826 0,20372543 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,17155826 0,20359425 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,17155826 0,20346323 ! carbohydrate transport GO:0008643 28 28 0,000 0,17155826 0,20333239 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,17155826 0,20320171 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,17155826 0,2030712 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,17155826 0,20294086 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,17155826 0,20281069 ! developmental growth GO:0048589 28 28 0,000 0,17155826 0,20268068 ! cartilage development GO:0051216 29 28 0,000 0,17155826 0,20255084 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,17711989 0,20898333 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,17711989 0,20884962 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,17711989 0,20871609 ! leukocyte migration GO:0050900 30 29 0,000 0,17711989 0,20858272 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,17711989 0,20844953 ! antigen processing and presentation GO:0019882 29 29 0,000 0,17711989 0,2083165 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,17711989 0,20818365 ! tRNA processing GO:0008033 29 29 0,000 0,17711989 0,20805096 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,17711989 0,20791844 ! adult behavior GO:0030534 30 29 0,000 0,17711989 0,2077861 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,17711989 0,20765392 ! response to UV GO:0009411 29 29 0,000 0,17711989 0,20752191 ! transition metal ion transport GO:0000041 31 30 0,000 0,18264499 0,21385942 ! RNA catabolic process GO:0006401 30 30 0,000 0,18264499 0,21372363 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,18264499 0,21358802 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,18264499 0,21345258 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,18264499 0,21331732 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,18264499 0,21318222 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,18264499 0,21304729 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,18264499 0,21291254 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,18264499 0,21277795 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,18264499 0,21264354 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,18264499 0,2125093 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,18264499 0,21237522 ! response to temperature stimulus GO:0009266 30 30 0,000 0,18264499 0,21224131 ! regulation of ossification GO:0030278 30 30 0,000 0,18264499 0,21210758 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,18264499 0,21197401 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,18264499 0,21184061 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,18264499 0,21170737 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,18264499 0,21157431 ! vesicle organization GO:0016050 30 30 0,000 0,18264499 0,21144141 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,18264499 0,21130868 ! establishment of organelle localization GO:0051656 31 30 0,000 0,18264499 0,21117611 ! regulation of translational initiation GO:0006446 31 31 0,000 0,1881338 0,21738595 ! membrane fusion GO:0006944 31 31 0,000 0,1881338 0,21724975 ! B cell activation GO:0042113 31 31 0,000 0,1881338 0,21711371 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,1881338 0,21697784 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,1881338 0,21684215 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,1881338 0,21670662 ! ion transmembrane transport GO:0034220 31 31 0,000 0,1881338 0,21657127 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,1881338 0,21643608 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,1881338 0,21630106 ! digestion GO:0007586 31 31 0,000 0,1881338 0,21616621 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,1881338 0,21603152 ! regulation of heart contraction GO:0008016 31 31 0,000 0,1881338 0,21589701 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,1881338 0,21576266 ! camera-type eye development GO:0043010 31 31 0,000 0,1881338 0,21562848 ! extracellular matrix organization GO:0030198 31 31 0,000 0,1881338 0,21549447 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,1881338 0,21536062 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,1881338 0,21522694 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,19358655 0,22132755 ! cell redox homeostasis GO:0045454 32 32 0,000 0,19358655 0,22119033 ! glucose catabolic process GO:0006007 32 32 0,000 0,19358655 0,22105329 ! lipid modification GO:0030258 32 32 0,000 0,19358655 0,22091641 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,19358655 0,22077971 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,19358655 0,22064317 ! cell maturation GO:0048469 32 32 0,000 0,19358655 0,2205068 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,19358655 0,2203706 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,19358655 0,22023457 ! nuclear export GO:0051168 32 32 0,000 0,19358655 0,22009871 ! kidney development GO:0001822 32 32 0,000 0,19358655 0,21996301 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,19358655 0,21982748 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,19358655 0,21969212 ! negative regulation of cell size GO:0045792 33 33 0,000 0,19900346 0,22570054 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,19900346 0,22556173 ! amino acid transport GO:0006865 33 33 0,000 0,19900346 0,22542309 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,19900346 0,22528463 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,19900346 0,22514633 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,19900346 0,2250082 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,19900346 0,22487025 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,19900346 0,22473246 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,19900346 0,22459484 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,19900346 0,22445739 ! regulation of actin filament length GO:0030832 34 34 0,000 0,20438477 0,23038601 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,20438477 0,23024519 ! ear development GO:0043583 34 34 0,000 0,20438477 0,23010454 ! muscle cell differentiation GO:0042692 35 34 0,000 0,20438477 0,22996406 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,20438477 0,22982375 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,20438477 0,22968362 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,20438477 0,22954365 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,20438477 0,22940386 ! secondary metabolic process GO:0019748 34 34 0,000 0,20438477 0,22926423 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,20438477 0,22912478 ! detection of stimulus GO:0051606 36 34 0,000 0,20438477 0,22898549 ! acute inflammatory response GO:0002526 35 35 0,000 0,20973071 0,23483214 ! regulation of cellular component size GO:0032535 35 35 0,000 0,20973071 0,23468956 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,20973071 0,23454715 ! mesoderm development GO:0007498 35 35 0,000 0,20973071 0,23440491 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,20973071 0,23426285 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,20973071 0,23412096 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,20973071 0,23397924 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,20973071 0,23383769 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,20973071 0,23369631 ! regulation of immune effector process GO:0002697 35 35 0,000 0,20973071 0,2335551 ! hydrogen transport GO:0006818 36 36 0,000 0,2150415 0,23932457 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,2150415 0,23918014 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,2150415 0,23903588 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,2150415 0,2388918 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,2150415 0,23874789 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,2150415 0,23860415 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,2150415 0,23846058 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,2150415 0,23831719 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,2150415 0,23817397 ! gonad development GO:0008406 36 36 0,000 0,2150415 0,23803093 ! regulation of lipase activity GO:0060191 36 36 0,000 0,2150415 0,23788805 ! activation of immune response GO:0002253 36 36 0,000 0,2150415 0,23774535 ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,22031738 0,24343221 ! response to drug GO:0042493 37 37 0,000 0,22031738 0,24328636 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,22031738 0,24314068 ! eye development GO:0001654 37 37 0,000 0,22031738 0,24299517 ! negative regulation of growth GO:0045926 37 37 0,000 0,22031738 0,24284984 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,22031738 0,24270468 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,22031738 0,2425597 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,22031738 0,24241488 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,22031738 0,24227024 ! adaptive immune response GO:0002250 37 37 0,000 0,22031738 0,24212578 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,22555856 0,24773804 ! neurotransmitter transport GO:0006836 40 38 0,000 0,22555856 0,24759049 ! exocytosis GO:0006887 40 38 0,000 0,22555856 0,24744311 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,22555856 0,24729591 ! hexose catabolic process GO:0019320 38 38 0,000 0,22555856 0,24714889 ! regulation of neurological system process GO:0031644 38 38 0,000 0,22555856 0,24700204 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,22555856 0,24685536 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,23076527 0,25240379 ! response to unfolded protein GO:0006986 39 39 0,000 0,23076527 0,25225409 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,23076527 0,25210456 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,23076527 0,25195521 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,23076527 0,25180603 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,23076527 0,25165704 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,23076527 0,25150821 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,23076527 0,25135957 ! developmental maturation GO:0021700 39 39 0,000 0,23076527 0,2512111 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,23076527 0,2510628 ! limb development GO:0060173 39 39 0,000 0,23076527 0,25091469 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,23593773 0,25638752 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,23593773 0,25623644 ! organelle localization GO:0051640 41 40 0,000 0,23593773 0,25608553 ! amine catabolic process GO:0009310 42 41 0,000 0,24107616 0,26150875 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,24107616 0,26135492 ! regulation of caspase activity GO:0043281 41 41 0,000 0,24107616 0,26120127 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,24107616 0,2610478 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,24107616 0,26089452 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,24107616 0,26074141 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,24107616 0,26058848 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,24618078 0,26595028 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,24618078 0,26579448 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,24618078 0,26563886 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,24618078 0,26548343 ! protein ubiquitination GO:0016567 43 42 0,000 0,24618078 0,26532817 ! response to protein stimulus GO:0051789 42 42 0,000 0,24618078 0,2651731 ! forebrain development GO:0030900 43 42 0,000 0,24618078 0,26501821 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,24618078 0,2648635 ! mitochondrion organization GO:0007005 44 43 0,000 0,25125181 0,27016166 ! alcohol catabolic process GO:0046164 43 43 0,000 0,25125181 0,27000413 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,25125181 0,26984678 ! humoral immune response GO:0006959 44 44 0,000 0,25628946 0,27509695 ! mRNA transport GO:0051028 44 44 0,000 0,25628946 0,27493683 ! protein import into nucleus GO:0006606 44 44 0,000 0,25628946 0,27477689 ! vitamin metabolic process GO:0006766 44 44 0,000 0,25628946 0,27461713 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,25628946 0,27445757 ! amine biosynthetic process GO:0009309 46 45 0,000 0,26129395 0,27965432 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,26129395 0,27949202 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,26129395 0,2793299 ! nuclear import GO:0051170 45 45 0,000 0,26129395 0,27916797 ! protein processing GO:0016485 45 45 0,000 0,26129395 0,27900622 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,26626549 0,28415014 ! tube morphogenesis GO:0035239 47 46 0,000 0,26626549 0,2839857 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,26626549 0,28382145 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,27120429 0,28891879 ! regulation of blood pressure GO:0008217 48 47 0,000 0,27120429 0,28875188 ! amine transport GO:0015837 47 47 0,000 0,27120429 0,28858517 ! rhythmic process GO:0048511 47 47 0,000 0,27120429 0,28841864 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,27611057 0,293467 ! protein localization in nucleus GO:0034504 48 48 0,000 0,27611057 0,29329786 ! DNA recombination GO:0006310 48 48 0,000 0,27611057 0,29312891 ! leukocyte differentiation GO:0002521 50 49 0,000 0,28098453 0,29813154 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,28098453 0,29796001 ! response to nutrient GO:0007584 49 49 0,000 0,28098453 0,29778867 ! response to bacterium GO:0009617 50 49 0,000 0,28098453 0,29761752 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,28098453 0,29744658 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,28098453 0,29727583 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,28582639 0,30222492 ! chromatin assembly GO:0031497 50 50 0,000 0,28582639 0,30205162 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,28582639 0,30187853 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,28582639 0,30170563 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,28582639 0,30153293 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,28582639 0,30136043 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,28582639 0,30118813 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,29063634 0,30608159 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,29063634 0,30590678 ! positive regulation of immune response GO:0050778 51 51 0,000 0,29063634 0,30573218 ! rRNA metabolic process GO:0016072 51 51 0,000 0,29063634 0,30555777 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,29063634 0,30538357 ! protein maturation GO:0051604 51 51 0,000 0,29063634 0,30520956 ! RNA localization GO:0006403 52 52 0,000 0,2954146 0,31005074 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,2954146 0,30987428 ! cell fate commitment GO:0045165 52 52 0,000 0,2954146 0,30969801 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,2954146 0,30952195 ! response to light stimulus GO:0009416 53 52 0,000 0,2954146 0,30934608 ! sodium ion transport GO:0006814 53 53 0,000 0,30016137 0,31413822 ! tRNA metabolic process GO:0006399 53 53 0,000 0,30016137 0,31395993 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,30016137 0,31378185 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,30016137 0,31360397 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,30016137 0,31342629 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,30487685 0,31816989 ! response to virus GO:0009615 54 54 0,000 0,30487685 0,31798983 ! nucleosome organization GO:0034728 55 55 0,000 0,30956124 0,32269308 ! in utero embryonic development GO:0001701 55 55 0,000 0,30956124 0,32251066 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,30956124 0,32232845 ! regulation of nervous system development GO:0051960 57 56 0,000 0,31421475 0,32698915 ! innate immune response GO:0045087 58 58 0,000 0,3234299 0,336389 ! dephosphorylation GO:0016311 60 59 0,000 0,32799193 0,34094142 ! carboxylic acid transport GO:0046942 59 59 0,000 0,32799193 0,34074923 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,32799193 0,34055726 ! sterol metabolic process GO:0016125 59 59 0,000 0,32799193 0,3403655 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,32799193 0,34017396 ! protein localization in organelle GO:0033365 59 59 0,000 0,32799193 0,33998264 ! immune effector process GO:0002252 59 59 0,000 0,32799193 0,33979153 ! potassium ion transport GO:0006813 60 60 0,000 0,33252388 0,34429298 ! protein polymerization GO:0051258 65 60 0,000 0,33252388 0,34409967 ! cellular respiration GO:0045333 62 61 0,000 0,33702591 0,34856272 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,33702591 0,34836722 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,33702591 0,34817195 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,33702591 0,3479769 ! lipid transport GO:0006869 62 62 0,000 0,34149824 0,35239712 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,34149824 0,35219992 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,34149824 0,35200294 ! protein import GO:0017038 62 62 0,000 0,34149824 0,35180618 ! regulation of secretion GO:0051046 65 63 0,000 0,34594105 0,356184 ! glucose metabolic process GO:0006006 63 63 0,000 0,34594105 0,35598513 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,35035454 0,36032556 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,35035454 0,3601246 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,35909427 0,36890231 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,35909427 0,3686968 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,35909427 0,36849151 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,36342091 0,37272383 ! muscle contraction GO:0006936 67 67 0,000 0,36342091 0,37251653 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,36342091 0,37230947 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,36342091 0,37210263 ! response to radiation GO:0009314 70 68 0,000 0,36771896 0,3762943 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,36771896 0,37608548 ! sensory perception of sound GO:0007605 71 69 0,000 0,37198862 0,38024128 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,37623007 0,38436365 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,38044349 0,38845283 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,38044349 0,38823774 ! ribosome biogenesis GO:0042254 71 71 0,000 0,38044349 0,38802289 ! secretion by cell GO:0032940 75 72 0,000 0,38462907 0,39207488 ! muscle system process GO:0003012 72 72 0,000 0,38462907 0,39185814 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,38462907 0,39164165 ! sensory organ development GO:0007423 72 72 0,000 0,38462907 0,39142539 ! regulation of cytokine production GO:0001817 72 72 0,000 0,38462907 0,39120937 ! electron transport chain GO:0022900 75 74 0,000 0,39291741 0,39941908 ! response to oxidative stress GO:0006979 76 75 0,000 0,39702052 0,4033676 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,4010965 0,40728422 ! regulation of protein modification process GO:0031399 79 78 0,000 0,40916777 0,41525121 ! regulation of immune response GO:0050776 78 78 0,000 0,40916777 0,41502267 ! nuclear transport GO:0051169 79 79 0,000 0,4131634 0,41884497 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,41713259 0,42263627 ! lymphocyte activation GO:0046649 82 81 0,000 0,42107552 0,42639681 ! lipid catabolic process GO:0016042 82 81 0,000 0,42107552 0,42616265 ! ncRNA processing GO:0034470 83 83 0,000 0,42888325 0,43382647 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,43658794 0,44137772 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,43658794 0,44113573 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,43658794 0,44089402 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,44040207 0,44450219 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,44040207 0,4442589 ! male gamete generation GO:0048232 90 88 0,000 0,44795468 0,45163046 GO:0007283|spermatogenesis, ! chemotaxis GO:0006935 90 89 0,000 0,45169351 0,45515097 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,45540755 0,45864269 ! DNA replication GO:0006260 91 91 0,000 0,45909699 0,46210581 ! visual perception GO:0007601 93 92 0,000 0,46276197 0,46554056 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,46276197 0,46528658 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,46276197 0,46503288 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,46276197 0,46477946 ! tissue morphogenesis GO:0048729 94 93 0,000 0,46640265 0,46818087 ! endocytosis GO:0006897 99 98 0,000 0,48424709 0,48582873 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,48424709 0,48556441 ! blood circulation GO:0008015 99 98 0,000 0,48424709 0,48530037 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,48424709 0,48503662 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,49122023 0,49175387 ! response to other organism GO:0051707 101 100 0,000 0,49122023 0,49148691 ! hemopoiesis GO:0030097 104 100 0,000 0,49122023 0,49122023