pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6878-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! sex determination GO:0007530 47 23 4,000 2,163E-07 5,205E-04 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 3,000 1,565E-06 1,883E-03 ! negative regulation of ligase activity GO:0051352 112 68 5,000 3,268E-06 2,621E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cell-substrate junction assembly GO:0007044 54 18 3,000 3,46E-06 2,081E-03 ! cell cycle checkpoint GO:0000075 137 69 5,000 3,562E-06 1,714E-03 ! C21-steroid hormone metabolic process GO:0008207 33 20 3,000 5,427E-06 2,176E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 5,000 7,863E-06 2,703E-03 ! regulation of ligase activity GO:0051340 142 84 5,000 1,122E-05 3,374E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,131E-05 3,024E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,131E-05 2,721E-03 ! negative regulation of DNA replication initiation GO:0032297 9 8 2,000 1,131E-05 2,474E-03 GO:0000076|DNA replication checkpoint, ! regulation of cell cycle process GO:0010564 149 90 5,000 1,669E-05 3,346E-03 ! middle ear morphogenesis GO:0042474 14 9 2,000 1,689E-05 3,126E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 2,286E-05 3,929E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,403E-05 3,854E-03 ! regulation of DNA replication initiation GO:0030174 14 10 2,000 2,403E-05 3,613E-03 ! cell junction assembly GO:0034329 78 30 3,000 2,93E-05 4,147E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,366E-05 5,836E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,366E-05 5,529E-03 GO:0042130|negative regulation of T cell proliferation, ! actin filament organization GO:0007015 148 66 4,000 4,673E-05 5,622E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 5,026E-05 5,758E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 4,000 5,399E-05 5,905E-03 ! cell junction organization GO:0034330 86 36 3,000 6,126E-05 6,408E-03 ! hormone biosynthetic process GO:0042446 57 36 3,000 6,126E-05 6,141E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 4,000 7,109E-05 6,842E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 7,161E-05 6,627E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,092E-04 9,732E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,32E-04 0,01134587 ! actin filament bundle formation GO:0051017 42 19 2,000 1,865E-04 0,01547433 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,914E-04 0,01535147 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,185E-04 0,01695624 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,185E-04 0,01642636 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 4,000 2,388E-04 0,01741284 GO:0010498|proteasomal protein catabolic process, ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,424E-04 0,01715679 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,538E-04 0,017445 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 2,906E-04 0,01941853 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,926E-04 0,01902426 ! negative regulation of cell motion GO:0051271 134 55 3,000 3,248E-04 0,02056658 ! cell cycle arrest GO:0007050 213 100 4,000 3,346E-04 0,02064242 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,472E-04 0,02088271 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 3,472E-04 0,02037338 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,472E-04 0,0198883 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,472E-04 0,01942578 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,472E-04 0,01898428 ! microvillus organization GO:0032528 7 5 1,000 3,472E-04 0,01856241 GO:0030033|microvillus assembly, ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,472E-04 0,01815888 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cellular glucose homeostasis GO:0001678 5 5 1,000 3,472E-04 0,01777252 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,472E-04 0,01740226 ! neural tube patterning GO:0021532 7 5 1,000 3,472E-04 0,01704711 ! stem cell division GO:0017145 11 5 1,000 3,472E-04 0,01670617 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 3,472E-04 0,0163786 ! regulation of DNA replication GO:0006275 101 56 3,000 3,482E-04 0,01611095 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,812E-04 0,01730326 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 3,812E-04 0,01698283 ! protein tetramerization GO:0051262 52 24 2,000 3,812E-04 0,01667405 ! DNA catabolic process GO:0006308 86 59 3,000 4,255E-04 0,01828282 ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 4,255E-04 0,01796207 ! negative regulation of DNA replication GO:0008156 42 25 2,000 4,312E-04 0,01788942 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,854E-04 0,01979344 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 4,854E-04 0,01946354 GO:0045936|negative regulation of phosphate metabolic process, ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 5,187E-04 0,02046 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 5,187E-04 0,02013 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! male sex determination GO:0030238 15 6 1,000 5,187E-04 0,01981048 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 5,187E-04 0,01950094 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,187E-04 0,01920093 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,437E-04 0,01981919 ! regulation of mitosis GO:0007088 105 63 3,000 5,468E-04 0,0196341 GO:0051783|regulation of nuclear division, ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,733E-04 0,02382172 ! cellular hormone metabolic process GO:0034754 113 67 3,000 6,907E-04 0,02408382 ! prostate gland development GO:0030850 13 7 1,000 7,234E-04 0,02486358 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 7,234E-04 0,02451339 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,234E-04 0,02417293 ! spindle checkpoint GO:0031577 15 7 1,000 7,234E-04 0,02384179 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 7,234E-04 0,0235196 ! cell differentiation in hindbrain GO:0021533 10 7 1,000 7,234E-04 0,02320601 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,234E-04 0,02290067 ! negative regulation of nuclear division GO:0051784 14 7 1,000 7,234E-04 0,02260326 GO:0045839|negative regulation of mitosis, ! negative regulation of nucleotide metabolic process GO:0045980 11 7 1,000 7,234E-04 0,02231347 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 7,448E-04 0,02268392 ! regulation of B cell activation GO:0050864 50 30 2,000 7,448E-04 0,02240037 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 8,21E-04 0,02438765 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 9,607E-04 0,02818938 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,607E-04 0,02784975 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,607E-04 0,02751821 ! formation of primary germ layer GO:0001704 72 33 2,000 9,879E-04 0,0279637 ! cell fate specification GO:0001708 52 33 2,000 9,879E-04 0,02763854 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,004E-03 0,02776421 GO:0090046|regulation of transcription regulator activity, ! steroid biosynthetic process GO:0006694 131 76 3,000 1,109E-03 0,03032552 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,175E-03 0,03175959 ! regulation of developmental growth GO:0048638 15 9 1,000 1,23E-03 0,03289282 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,23E-03 0,03253136 ! regulation of glycolysis GO:0006110 21 9 1,000 1,23E-03 0,03217776 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,23E-03 0,03183176 ! receptor clustering GO:0043113 18 9 1,000 1,23E-03 0,03149313 ! motor axon guidance GO:0008045 16 9 1,000 1,23E-03 0,03116162 ! protein heterooligomerization GO:0051291 16 9 1,000 1,23E-03 0,03083702 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,23E-03 0,03051911 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,276E-03 0,03132825 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,276E-03 0,03101181 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,383E-03 0,03326553 ! regulation of protein stability GO:0031647 73 37 2,000 1,383E-03 0,03293616 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,383E-03 0,03261326 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,495E-03 0,03491263 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,495E-03 0,03457693 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 2,000 1,495E-03 0,03424763 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,532E-03 0,03477349 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,532E-03 0,03444851 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,532E-03 0,03412954 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,532E-03 0,03381643 GO:0043470|regulation of carbohydrate catabolic process, ! ear morphogenesis GO:0042471 60 39 2,000 1,612E-03 0,03526141 ! negative regulation of binding GO:0051100 72 40 2,000 1,735E-03 0,03761305 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 1,735E-03 0,03727722 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,864E-03 0,03969125 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,864E-03 0,03934308 ! neuron fate specification GO:0048665 17 11 1,000 1,865E-03 0,03902185 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,865E-03 0,03868546 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,865E-03 0,03835481 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,865E-03 0,03802977 ! adult heart development GO:0007512 14 11 1,000 1,865E-03 0,03771019 ! positive regulation of neuron differentiation GO:0045666 19 11 1,000 1,865E-03 0,03739594 ! regulation of embryonic development GO:0045995 27 11 1,000 1,865E-03 0,03708688 ! regulation of DNA binding GO:0051101 155 88 3,000 1,908E-03 0,03762413 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,229E-03 0,04360979 ! virus-host interaction GO:0019048 29 12 1,000 2,229E-03 0,0432581 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,229E-03 0,04291204 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,229E-03 0,04257146 ! focal adhesion formation GO:0048041 35 12 1,000 2,229E-03 0,04223626 ! protein homotetramerization GO:0051289 21 12 1,000 2,229E-03 0,04190628 ! histone acetylation GO:0016573 26 12 1,000 2,229E-03 0,04158143 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,229E-03 0,04126157 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 2,439E-03 0,04478971 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,439E-03 0,0444504 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,522E-03 0,04562776 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,598E-03 0,0466389 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,598E-03 0,04629342 ! response to insulin stimulus GO:0032868 95 46 2,000 2,598E-03 0,04595303 ! endocrine pancreas development GO:0031018 22 13 1,000 2,625E-03 0,04609164 ! plasma membrane organization GO:0007009 24 13 1,000 2,625E-03 0,04575765 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,625E-03 0,04542845 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! actin filament polymerization GO:0030041 24 13 1,000 2,625E-03 0,04510397 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,625E-03 0,04478408 ! hormone metabolic process GO:0042445 157 97 3,000 2,72E-03 0,04608746 ! interphase GO:0051325 213 98 3,000 2,823E-03 0,04749446 ! cellular component disassembly GO:0022411 86 48 2,000 2,934E-03 0,04902237 ! activation of caspase activity GO:0006919 84 48 2,000 2,934E-03 0,04868429 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,934E-03 0,04835084 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,05E-03 0,04992016 ! regulation of S phase GO:0033261 23 14 1,000 3,05E-03 0,04958286 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,05E-03 0,04925009 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,05E-03 0,04892176 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,296E-03 0,05251971 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,506E-03 0,0554884 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,506E-03 0,05512573 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 3,506E-03 0,05476777 ! mRNA splice site selection GO:0006376 38 15 1,000 3,506E-03 0,05441443 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 3,684E-03 0,05682573 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,991E-03 0,06115662 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,991E-03 0,06076955 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 3,991E-03 0,06038736 ! response to osmotic stress GO:0006970 25 16 1,000 3,991E-03 0,06000993 ! intermediate filament-based process GO:0045103 32 16 1,000 3,991E-03 0,0596372 ! axon cargo transport GO:0008088 43 16 1,000 3,991E-03 0,05926907 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,991E-03 0,05890546 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,317E-03 0,06333881 GO:0010952|positive regulation of peptidase activity, ! gastrulation GO:0007369 112 55 2,000 4,317E-03 0,06295494 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,505E-03 0,06529785 ! signal complex assembly GO:0007172 41 17 1,000 4,505E-03 0,06490685 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,505E-03 0,0645205 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,505E-03 0,06413872 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,505E-03 0,06376143 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,049E-03 0,07103468 ! memory GO:0007613 31 18 1,000 5,049E-03 0,07062168 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,049E-03 0,07021347 ! skeletal system morphogenesis GO:0048705 105 59 2,000 5,258E-03 0,07270569 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 5,511E-03 0,07576658 ! lipid phosphorylation GO:0046834 35 19 1,000 5,621E-03 0,07683628 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,621E-03 0,07640218 ! neuromuscular junction development GO:0007528 34 19 1,000 5,621E-03 0,07597295 ! G1 phase GO:0051318 40 19 1,000 5,621E-03 0,07554852 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,771E-03 0,07713781 ! ear development GO:0043583 103 62 2,000 6,038E-03 0,08026454 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,221E-03 0,08223822 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,221E-03 0,08178883 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,221E-03 0,08134433 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,221E-03 0,08090463 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 6,221E-03 0,08046966 ! pancreas development GO:0031016 35 20 1,000 6,221E-03 0,08003934 ! cellular response to starvation GO:0009267 33 20 1,000 6,221E-03 0,0796136 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 6,221E-03 0,07919236 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 6,221E-03 0,07877556 ! negative regulation of translation GO:0017148 29 20 1,000 6,221E-03 0,07836312 ! positive regulation of cell motion GO:0051272 146 64 2,000 6,595E-03 0,0826395 ! collagen catabolic process GO:0030574 28 21 1,000 6,849E-03 0,08538133 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 7,485E-03 0,09282865 ! negative regulation of cell growth GO:0030308 132 67 2,000 7,485E-03 0,0923526 ! lung development GO:0030324 144 67 2,000 7,485E-03 0,09188142 ! microtubule-based transport GO:0010970 54 22 1,000 7,505E-03 0,09165516 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 7,505E-03 0,09119226 ! ureteric bud development GO:0001657 43 22 1,000 7,505E-03 0,090734 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,505E-03 0,09028033 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,505E-03 0,08983118 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 7,505E-03 0,08938647 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,505E-03 0,08894614 ! protein stabilization GO:0050821 39 22 1,000 7,505E-03 0,08851013 ! negative regulation of kinase activity GO:0033673 131 68 2,000 7,797E-03 0,09150641 ! negative regulation of cell size GO:0045792 134 69 2,000 8,116E-03 0,09479162 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 8,116E-03 0,09433369 ! urogenital system development GO:0001655 137 69 2,000 8,116E-03 0,09388016 ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,187E-03 0,09425328 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,187E-03 0,09380445 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 8,187E-03 0,09335988 ! leukocyte adhesion GO:0007159 50 23 1,000 8,187E-03 0,0929195 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,187E-03 0,09248326 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 8,187E-03 0,0920511 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 8,187E-03 0,09162295 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,187E-03 0,09119877 ! respiratory tube development GO:0030323 150 70 2,000 8,443E-03 0,09361121 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,897E-03 0,09819439 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,897E-03 0,09774601 ! regulation of transmembrane transport GO:0034762 38 24 1,000 8,897E-03 0,09730171 ! regulation of caspase activity GO:0043281 122 72 2,000 9,12E-03 0,09928512 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 9,12E-03 0,09883789 ! negative regulation of transferase activity GO:0051348 140 72 2,000 9,12E-03 0,09839467 ! respiratory system development GO:0060541 153 72 2,000 9,12E-03 0,09795541 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 9,633E-03 0,10301145 ! myelination GO:0042552 45 25 1,000 9,633E-03 0,10255564 ! receptor metabolic process GO:0043112 46 25 1,000 9,633E-03 0,10210386 ! response to starvation GO:0042594 42 25 1,000 9,633E-03 0,10165603 ! interaction with host GO:0051701 62 25 1,000 9,633E-03 0,10121212 ! somitogenesis GO:0001756 43 25 1,000 9,633E-03 0,10077207 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,633E-03 0,10033583 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 9,827E-03 0,10191659 ! cell-matrix adhesion GO:0007160 163 75 2,000 0,01019286 0,10525328 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01019286 0,10480348 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01039556 0,10643286 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01039556 0,10598188 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01039556 0,10553469 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01056616 0,10681589 ! positive regulation of ligase activity GO:0051351 124 77 2,000 0,01094731 0,11020593 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01118371 0,11211673 ! neuron fate commitment GO:0048663 48 27 1,000 0,01118371 0,11165152 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01118371 0,11119015 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 0,01118371 0,11073257 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01118371 0,11027875 ! glutathione metabolic process GO:0006749 39 27 1,000 0,01118371 0,10982863 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01118371 0,10938218 ! blood coagulation GO:0007596 146 78 2,000 0,01133632 0,11042588 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 2,000 0,01133632 0,10998061 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01173324 0,11337417 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01199736 0,11546263 ! response to hypoxia GO:0001666 171 81 2,000 0,01255086 0,12030826 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01255086 0,11983085 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01255086 0,11935721 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01283619 0,12159002 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01283619 0,12111319 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01297162 0,12191294 ! response to oxygen levels GO:0070482 176 83 2,000 0,01340037 0,12545245 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01369986 0,12775912 GO:0008366|axon ensheathment, ! hemostasis GO:0007599 158 84 2,000 0,01383713 0,12854102 ! negative regulation of growth GO:0045926 155 84 2,000 0,01383713 0,12804663 ! collagen metabolic process GO:0032963 45 31 1,000 0,01458805 0,13447835 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01458805 0,13396507 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01458805 0,1334557 ! mesoderm formation GO:0001707 69 31 1,000 0,01458805 0,13295019 ! tube morphogenesis GO:0035239 176 86 2,000 0,01473475 0,13378045 ! mitochondrion organization GO:0007005 148 86 2,000 0,01473475 0,13327752 ! spliceosome assembly GO:0000245 67 32 1,000 0,01550045 0,13967823 ! spindle organization GO:0007051 46 32 1,000 0,01550045 0,13915704 ! metanephros development GO:0001656 74 32 1,000 0,01550045 0,13863973 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01550045 0,13812625 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01550045 0,13761656 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01550045 0,13711062 ! hindbrain development GO:0030902 61 32 1,000 0,01550045 0,13660838 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01550045 0,13610981 ! gland development GO:0048732 206 88 2,000 0,01566464 0,13705138 ! ATP biosynthetic process GO:0006754 159 88 2,000 0,01566464 0,13655481 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01614172 0,14020569 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01643675 0,14225471 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01739662 0,15002243 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01739662 0,14948664 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01739662 0,14895466 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01739662 0,14842645 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01813121 0,1541473 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 0,01813121 0,15360453 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01837976 0,15516383 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01837976 0,1546213 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01837976 0,15408255 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01837976 0,15354754 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01837976 0,15301624 ! transcription initiation GO:0006352 153 94 2,000 0,01864892 0,15472177 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01864892 0,15419008 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01938586 0,15973415 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01938586 0,15918898 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01938586 0,15864752 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01938586 0,15810973 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 2,000 0,01970883 0,16020079 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 2,000 0,02025102 0,16405372 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02041461 0,16482403 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 2,000 0,02080138 0,16738506 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02135992 0,17130657 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02146573 0,17158317 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02146573 0,17101502 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,02253889 0,1789722 ! segmentation GO:0035282 67 39 1,000 0,02253889 0,17838348 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02253889 0,17779862 ! maintenance of protein location GO:0045185 91 40 1,000 0,02363382 0,18582671 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02475022 0,19397074 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02475022 0,19334097 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02588779 0,20157285 GO:0090047|positive regulation of transcription regulator activity, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02588779 0,20092262 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02588779 0,20027656 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02704624 0,20856814 ! neural tube development GO:0021915 77 43 1,000 0,02704624 0,20790178 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,02704624 0,20723968 ! maintenance of location in cell GO:0051651 97 44 1,000 0,0282253 0,21558754 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02936821 0,22360729 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02936821 0,2229019 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02936821 0,22220095 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02936821 0,2215044 ! neuron fate determination GO:0048664 7 5 0,000 0,02936821 0,22081219 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02936821 0,22012431 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02936821 0,21944069 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02936821 0,21876131 ! polyol transport GO:0015791 12 5 0,000 0,02936821 0,21808612 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02936821 0,21741508 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02936821 0,21674817 ! response to superoxide GO:0000303 10 5 0,000 0,02936821 0,21608533 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02936821 0,21542653 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02936821 0,21477174 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02936821 0,21412092 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02936821 0,21347402 ! female meiosis GO:0007143 7 5 0,000 0,02936821 0,21283103 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02936821 0,2121919 ! cobalt ion transport GO:0006824 11 5 0,000 0,02936821 0,21155659 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02936821 0,21092508 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02936821 0,21029733 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02936821 0,2096733 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02936821 0,20905297 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02936821 0,20843629 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02936821 0,20782324 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02936821 0,20721379 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02936821 0,2066079 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02936821 0,20600555 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02936821 0,20540669 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02936821 0,20481131 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02936821 0,20421937 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02936821 0,20363084 ! negative chemotaxis GO:0050919 14 5 0,000 0,02936821 0,2030457 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02936821 0,2024639 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02936821 0,20188543 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02936821 0,20131026 ! behavioral response to pain GO:0048266 9 5 0,000 0,02936821 0,20073836 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02936821 0,20016969 ! Notch receptor processing GO:0007220 8 5 0,000 0,02936821 0,19960424 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02936821 0,19904198 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02936821 0,19848287 ! micturition GO:0060073 9 5 0,000 0,02936821 0,1979269 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02936821 0,19737403 ! copulation GO:0007620 9 5 0,000 0,02936821 0,19682424 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02936821 0,19627751 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02936821 0,1957338 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02936821 0,1951931 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02936821 0,19465538 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02936821 0,19412061 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02936821 0,19358877 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02936821 0,19305984 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02936821 0,19253379 ! grooming behavior GO:0007625 6 5 0,000 0,02936821 0,1920106 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02936821 0,19149025 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02936821 0,19097271 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02936821 0,19045796 ! response to protozoan GO:0001562 10 5 0,000 0,02936821 0,18994597 ! lymph vessel development GO:0001945 10 5 0,000 0,02936821 0,18943674 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02936821 0,18893022 ! endochondral ossification GO:0001958 16 5 0,000 0,02936821 0,18842641 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02936821 0,18792527 ! parathyroid gland development GO:0060017 13 5 0,000 0,02936821 0,1874268 ! anagen GO:0042640 6 5 0,000 0,02936821 0,18693096 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02936821 0,18643774 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02936821 0,18594711 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02936821 0,18545906 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02936821 0,18497357 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02936821 0,18449061 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02936821 0,18401016 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02936821 0,18353221 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02936821 0,18305674 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02936821 0,18258373 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02936821 0,18211315 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02936821 0,18164499 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02936821 0,18117924 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02936821 0,18071586 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02936821 0,18025485 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02936821 0,17979619 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02936821 0,17933985 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02936821 0,17888583 ! histidine catabolic process GO:0006548 6 5 0,000 0,02936821 0,1784341 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02936821 0,17798464 ! valine metabolic process GO:0006573 10 5 0,000 0,02936821 0,17753744 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02936821 0,17709249 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02936821 0,17664976 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02936821 0,17620923 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02936821 0,1757709 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02936821 0,17533474 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02936821 0,17490075 ! polyol catabolic process GO:0046174 7 5 0,000 0,02936821 0,17446889 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02936821 0,17403917 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02936821 0,17361155 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02936821 0,17318603 ! muscle cell migration GO:0014812 8 5 0,000 0,02936821 0,1727626 ! mitochondrial fission GO:0000266 8 5 0,000 0,02936821 0,17234122 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02936821 0,1719219 ! mRNA transcription GO:0009299 9 5 0,000 0,02936821 0,17150462 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02936821 0,17108935 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02936821 0,17067609 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02936821 0,17026482 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02936821 0,16985553 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02936821 0,16944821 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02936821 0,16904283 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02936821 0,16863938 ! response to food GO:0032094 6 5 0,000 0,02936821 0,16823786 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02936821 0,16783825 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02936821 0,16744053 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02936821 0,16704469 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02936821 0,16665071 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02936821 0,16625859 ! forebrain neuron development GO:0021884 13 5 0,000 0,02936821 0,16586832 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02936821 0,16547986 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02936821 0,16509323 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02936821 0,1647084 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02936821 0,16432535 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02936821 0,16394409 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02936821 0,16356459 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02936821 0,16318684 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02936821 0,16281083 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02936821 0,16243656 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02936821 0,162064 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02936821 0,16169314 ! basic amino acid transport GO:0015802 11 5 0,000 0,02936821 0,16132398 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02936821 0,1609565 ! depyrimidination GO:0045008 10 5 0,000 0,02936821 0,16059069 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02936821 0,16022654 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02936821 0,15986403 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02936821 0,15950317 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02936821 0,15914392 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02936821 0,1587863 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02936821 0,15843027 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02936821 0,15807584 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02936821 0,157723 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02936821 0,15737172 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02936821 0,157022 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02936821 0,15667384 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02936821 0,15632722 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02936821 0,15598212 ! response to arsenic GO:0046685 10 5 0,000 0,02936821 0,15563855 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02936821 0,15529649 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02936821 0,15495593 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02936821 0,15461685 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02936821 0,15427926 ! response to cadmium ion GO:0046686 7 5 0,000 0,02936821 0,15394314 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02936821 0,15360848 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02936821 0,15327528 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02936821 0,15294351 ! decidualization GO:0046697 11 5 0,000 0,02936821 0,15261318 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02936821 0,15228427 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02936821 0,15195678 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02936821 0,15163069 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02936821 0,151306 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02936821 0,1509827 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02936821 0,15066077 ! embryonic cleavage GO:0040016 6 5 0,000 0,02936821 0,15034022 ! peroxisome fission GO:0016559 5 5 0,000 0,02936821 0,15002102 ! histone demethylation GO:0016577 10 5 0,000 0,02936821 0,14970318 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02936821 0,14938669 ! mitotic recombination GO:0006312 9 5 0,000 0,02936821 0,14907152 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02936821 0,14875769 ! metaphase plate congression GO:0051310 7 5 0,000 0,02936821 0,14844517 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02936821 0,14813397 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02936821 0,14782406 ! enteric nervous system development GO:0048484 8 5 0,000 0,02936821 0,14751545 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02936821 0,14720813 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02936821 0,14690208 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02936821 0,14659731 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02936821 0,14629379 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02936821 0,14599153 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02936821 0,14569052 ! plasminogen activation GO:0031639 5 5 0,000 0,02936821 0,14539075 ! B cell homeostasis GO:0001782 13 5 0,000 0,02936821 0,1450922 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02936821 0,14479488 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02936821 0,14449878 ! metaphase GO:0051323 8 5 0,000 0,02936821 0,14420388 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02936821 0,14391019 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02936821 0,14361769 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02936821 0,14332637 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02936821 0,14303624 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02936821 0,14274728 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02936821 0,14245948 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02936821 0,14217284 ! response to redox state GO:0051775 5 5 0,000 0,02936821 0,14188735 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02936821 0,14160301 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02936821 0,1413198 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02936821 0,14103773 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02936821 0,14075678 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02936821 0,14047694 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02936821 0,14019822 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02936821 0,1399206 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02936821 0,13964408 ! striatum development GO:0021756 9 5 0,000 0,02936821 0,13936864 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02936821 0,1390943 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02936821 0,13882103 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02936821 0,13854883 ! glial cell migration GO:0008347 11 5 0,000 0,02936821 0,1382777 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02936821 0,13800762 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02936821 0,1377386 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02936821 0,13747063 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02936821 0,13720369 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02936821 0,1369378 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02936821 0,13667293 ! neuroprotection GO:0043526 6 5 0,000 0,02936821 0,13640908 ! neural plate development GO:0001840 8 5 0,000 0,02936821 0,13614625 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02936821 0,13588443 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02936821 0,13562361 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02936821 0,1353638 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02936821 0,13510498 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02936821 0,13484714 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02936821 0,13459029 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02936821 0,13433441 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02936821 0,13407951 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02936821 0,13382557 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02936821 0,13357259 ! spindle assembly GO:0051225 6 5 0,000 0,02936821 0,13332057 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02936821 0,1330695 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02936821 0,13281937 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02936821 0,13257017 ! drug metabolic process GO:0017144 6 5 0,000 0,02936821 0,13232191 ! organ regeneration GO:0031100 7 5 0,000 0,02936821 0,13207458 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02936821 0,13182818 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02936821 0,13158269 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02936821 0,13133811 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02942468 0,13134653 ! cell growth GO:0016049 84 45 1,000 0,02942468 0,13110329 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,0306441 0,13628409 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,0306441 0,13603265 ! pigmentation GO:0043473 100 46 1,000 0,0306441 0,13578213 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,0306441 0,13553253 ! response to calcium ion GO:0051592 81 47 1,000 0,03188327 0,14075441 ! endosome transport GO:0016197 108 47 1,000 0,03188327 0,14049662 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03188327 0,14023977 ! protein homooligomerization GO:0051260 76 47 1,000 0,03188327 0,13998386 ! regulation of action potential GO:0001508 95 49 1,000 0,03441981 0,15084531 ! peptide metabolic process GO:0006518 76 49 1,000 0,03441981 0,15057104 ! endocrine system development GO:0035270 104 49 1,000 0,03441981 0,15029777 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,03441981 0,15002549 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03441981 0,1497542 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0351381 0,15260338 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0351381 0,15232842 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0351381 0,15205444 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0351381 0,15178146 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0351381 0,15150945 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0351381 0,15123841 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0351381 0,15096834 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0351381 0,15069923 ! sleep GO:0030431 13 6 0,000 0,0351381 0,15043109 ! response to oxygen radical GO:0000305 11 6 0,000 0,0351381 0,15016389 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0351381 0,14989764 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0351381 0,14963234 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0351381 0,14936797 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0351381 0,14910453 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0351381 0,14884203 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0351381 0,14858044 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0351381 0,14831977 ! forebrain regionalization GO:0021871 8 6 0,000 0,0351381 0,14806002 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0351381 0,14780117 ! male meiosis GO:0007140 7 6 0,000 0,0351381 0,14754323 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0351381 0,14728619 ! response to zinc ion GO:0010043 9 6 0,000 0,0351381 0,14703004 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0351381 0,14677478 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0351381 0,1465204 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0351381 0,1462669 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0351381 0,14601428 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0351381 0,14576254 ! malate metabolic process GO:0006108 11 6 0,000 0,0351381 0,14551165 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0351381 0,14526163 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0351381 0,14501247 ! protein refolding GO:0042026 15 6 0,000 0,0351381 0,14476416 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0351381 0,1445167 ! opsonization GO:0008228 8 6 0,000 0,0351381 0,14427009 ! mating behavior GO:0007617 7 6 0,000 0,0351381 0,14402431 ! neuron remodeling GO:0016322 15 6 0,000 0,0351381 0,14377937 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0351381 0,14353526 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0351381 0,14329198 ! equilibrioception GO:0050957 14 6 0,000 0,0351381 0,14304953 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0351381 0,14280789 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0351381 0,14256707 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0351381 0,14232705 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0351381 0,14208785 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0351381 0,14184945 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0351381 0,14161184 ! toxin metabolic process GO:0009404 11 6 0,000 0,0351381 0,14137503 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0351381 0,14113902 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0351381 0,14090378 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0351381 0,14066934 ! nuclear migration GO:0007097 12 6 0,000 0,0351381 0,14043567 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0351381 0,14020277 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0351381 0,13997065 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0351381 0,13973929 ! thymic T cell selection GO:0045061 12 6 0,000 0,0351381 0,1395087 ! protein lipoylation GO:0009249 10 6 0,000 0,0351381 0,13927886 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0351381 0,13904979 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0351381 0,13882146 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0351381 0,13859389 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0351381 0,13836706 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0351381 0,13814097 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,0351381 0,13791561 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0351381 0,13769099 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0351381 0,13746711 ! hyperosmotic response GO:0006972 9 6 0,000 0,0351381 0,13724395 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0351381 0,13702151 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0351381 0,13679979 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0351381 0,13657879 ! urea metabolic process GO:0019627 7 6 0,000 0,0351381 0,1363585 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0351381 0,13613892 ! neutrophil activation GO:0042119 8 6 0,000 0,0351381 0,13592005 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0351381 0,13570188 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0351381 0,13548441 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0351381 0,13526763 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0351381 0,13505155 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0351381 0,13483616 ! neuron apoptosis GO:0051402 9 6 0,000 0,0351381 0,13462145 ! nucleoside salvage GO:0043174 9 6 0,000 0,0351381 0,13440743 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0351381 0,13419408 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0351381 0,13398141 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0351381 0,13376942 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0351381 0,13355809 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0351381 0,13334743 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0351381 0,13313743 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0351381 0,1329281 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0351381 0,13271942 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0351381 0,1325114 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0351381 0,13230402 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0351381 0,1320973 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0351381 0,13189122 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0351381 0,13168578 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0351381 0,13148098 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0351381 0,13127682 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0351381 0,13107329 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0351381 0,13087039 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0351381 0,13066812 ! neural nucleus development GO:0048857 14 6 0,000 0,0351381 0,13046647 ! response to UV-C GO:0010225 11 6 0,000 0,0351381 0,13026544 ! astrocyte development GO:0014002 15 6 0,000 0,0351381 0,13006503 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0351381 0,12986524 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0351381 0,12966606 ! interaction with symbiont GO:0051702 13 6 0,000 0,0351381 0,12946749 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0351381 0,12926953 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0351381 0,12907217 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0351381 0,12887541 ! response to copper ion GO:0046688 10 6 0,000 0,0351381 0,12867926 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0351381 0,12848369 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0351381 0,12828873 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0351381 0,12809435 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0351381 0,12790056 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0351381 0,12770736 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0351381 0,12751474 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0351381 0,1273227 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0351381 0,12713123 ! hair follicle maturation GO:0048820 7 6 0,000 0,0351381 0,12694035 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0351381 0,12675003 ! Schwann cell development GO:0014044 15 6 0,000 0,0351381 0,12656029 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0351381 0,12637111 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0351381 0,12618249 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0351381 0,12599444 ! subpallium development GO:0021544 10 6 0,000 0,0351381 0,12580695 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0351381 0,12562002 ! histone ubiquitination GO:0016574 8 6 0,000 0,0351381 0,12543364 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0351381 0,12524781 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0351381 0,12506253 ! G2 phase GO:0051319 16 6 0,000 0,0351381 0,1248778 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0351381 0,12469361 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0351381 0,12450997 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0351381 0,12432687 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0351381 0,1241443 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0351381 0,12396227 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0351381 0,12378078 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0351381 0,12359981 ! receptor internalization GO:0031623 10 6 0,000 0,0351381 0,12341937 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0351381 0,12323946 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0351381 0,12306007 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0351381 0,12288121 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0351381 0,12270286 ! protein deubiquitination GO:0016579 14 6 0,000 0,0351381 0,12252503 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0351381 0,12234771 ! protein destabilization GO:0031648 9 6 0,000 0,0351381 0,12217091 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0351381 0,12199462 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0351381 0,12181883 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0351381 0,12164355 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0351381 0,12146878 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0351381 0,12129451 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0351381 0,12112073 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0351381 0,12094745 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0351381 0,12077467 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0351381 0,12060238 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0351381 0,12043058 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0351381 0,12025928 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0351381 0,12008845 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0351381 0,11991811 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0351381 0,11974826 ! catecholamine transport GO:0051937 9 6 0,000 0,0351381 0,11957888 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0351381 0,11940999 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0351381 0,11924157 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0351381 0,11907362 ! maternal placenta development GO:0001893 12 6 0,000 0,0351381 0,11890615 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0351381 0,11873914 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0351381 0,11857261 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0351381 0,11840654 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0351381 0,11824094 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0351381 0,1180758 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0351381 0,11791112 ! inner ear development GO:0048839 79 50 1,000 0,03571663 0,11968555 ! histone modification GO:0016570 91 50 1,000 0,03571663 0,11951909 ! positive regulation of binding GO:0051099 78 51 1,000 0,03703213 0,12374904 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03703213 0,1235774 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03703213 0,12340624 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03703213 0,12323556 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03836604 0,12749819 ! positive regulation of growth GO:0045927 90 52 1,000 0,03836604 0,12732233 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03836604 0,12714695 ! synapse organization GO:0050808 85 52 1,000 0,03836604 0,12697206 ! response to UV GO:0009411 104 53 1,000 0,03971809 0,13126611 ! tRNA transcription GO:0009304 14 7 0,000 0,04087389 0,13490065 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04087389 0,13471585 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04087389 0,13453156 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04087389 0,13434778 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04087389 0,13416449 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04087389 0,13398171 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04087389 0,13379942 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04087389 0,13361763 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04087389 0,13343633 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04087389 0,13325552 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04087389 0,1330752 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04087389 0,13289537 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04087389 0,13271602 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04087389 0,13253716 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04087389 0,13235878 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04087389 0,13218088 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04087389 0,13200345 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04087389 0,13182651 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04087389 0,13165003 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04087389 0,13147403 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04087389 0,1312985 ! glycolipid transport GO:0046836 10 7 0,000 0,04087389 0,13112343 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04087389 0,13094883 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04087389 0,1307747 ! neuron adhesion GO:0007158 12 7 0,000 0,04087389 0,13060103 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04087389 0,13042782 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04087389 0,13025506 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04087389 0,13008277 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04087389 0,12991093 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04087389 0,12973954 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04087389 0,12956861 ! mRNA stabilization GO:0048255 18 7 0,000 0,04087389 0,12939812 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04087389 0,12922809 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04087389 0,1290585 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04087389 0,12888935 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04087389 0,12872065 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04087389 0,12855238 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04087389 0,12838456 ! lipoprotein transport GO:0042953 14 7 0,000 0,04087389 0,12821718 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04087389 0,12805023 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04087389 0,12788371 ! rhythmic behavior GO:0007622 15 7 0,000 0,04087389 0,12771763 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04087389 0,12755198 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04087389 0,12738675 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04087389 0,12722196 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04087389 0,12705759 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04087389 0,12689364 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04087389 0,12673012 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04087389 0,12656702 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04087389 0,12640434 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04087389 0,12624207 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04087389 0,12608022 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04087389 0,12591879 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04087389 0,12575777 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04087389 0,12559716 ! spinal cord patterning GO:0021511 13 7 0,000 0,04087389 0,12543696 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04087389 0,12527716 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04087389 0,12511778 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04087389 0,1249588 ! adrenal gland development GO:0030325 17 7 0,000 0,04087389 0,12480022 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04087389 0,12464205 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04087389 0,12448427 ! ovulation GO:0030728 9 7 0,000 0,04087389 0,1243269 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04087389 0,12416992 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04087389 0,12401333 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04087389 0,12385715 ! microtubule nucleation GO:0007020 20 7 0,000 0,04087389 0,12370135 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04087389 0,12354595 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04087389 0,12339093 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04087389 0,12323631 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04087389 0,12308207 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04087389 0,12292822 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04087389 0,12277475 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04087389 0,12262166 ! galactose metabolic process GO:0006012 13 7 0,000 0,04087389 0,12246896 ! vesicle fusion GO:0006906 17 7 0,000 0,04087389 0,12231663 ! response to dietary excess GO:0002021 8 7 0,000 0,04087389 0,12216469 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04087389 0,12201312 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04087389 0,12186193 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04087389 0,12171111 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04087389 0,12156066 ! organ growth GO:0035265 15 7 0,000 0,04087389 0,12141059 ! purine salvage GO:0043101 10 7 0,000 0,04087389 0,12126088 ! nucleoside transport GO:0015858 8 7 0,000 0,04087389 0,12111154 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04087389 0,12096258 ! parturition GO:0007567 14 7 0,000 0,04087389 0,12081397 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04087389 0,12066573 ! rRNA modification GO:0000154 14 7 0,000 0,04087389 0,12051786 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04087389 0,12037035 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04087389 0,1202232 ! macrophage differentiation GO:0030225 11 7 0,000 0,04087389 0,1200764 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04087389 0,11992997 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04087389 0,11978389 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04087389 0,11963817 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04087389 0,1194928 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04087389 0,11934778 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04087389 0,11920312 ! fibrinolysis GO:0042730 10 7 0,000 0,04087389 0,11905881 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04087389 0,11891484 ! eating behavior GO:0042755 7 7 0,000 0,04087389 0,11877122 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04087389 0,11862795 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04087389 0,11848503 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04087389 0,11834245 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04087389 0,11820021 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04087389 0,11805831 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04087389 0,11791676 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04087389 0,11777554 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04087389 0,11763466 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04087389 0,11749411 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04087389 0,11735391 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04087389 0,11721403 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04087389 0,11707449 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04087389 0,11693528 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04087389 0,11679641 ! regulation of meiosis GO:0040020 12 7 0,000 0,04087389 0,11665786 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04087389 0,11651964 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04087389 0,11638174 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04087389 0,11624418 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04087389 0,11610694 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04087389 0,11597002 ! transcription termination GO:0006353 13 7 0,000 0,04087389 0,11583342 ! response to tumor cell GO:0002347 13 7 0,000 0,04087389 0,11569715 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04087389 0,11556119 ! anaphase GO:0051322 17 7 0,000 0,04087389 0,11542556 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04087389 0,11529024 ! axonal fasciculation GO:0007413 18 7 0,000 0,04087389 0,11515524 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04087389 0,11502055 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04087389 0,11488618 ! diuresis GO:0030146 12 7 0,000 0,04087389 0,11475213 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04087389 0,11461838 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04087389 0,11448495 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04087389 0,11435183 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04087389 0,11421902 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04087389 0,11408651 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04087389 0,11395432 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04087389 0,11382242 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04087389 0,11369084 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04087389 0,11355955 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04087389 0,11342857 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04087389 0,1132979 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04087389 0,11316752 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04087389 0,11303744 ! lymph node development GO:0048535 10 7 0,000 0,04087389 0,11290766 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04087389 0,11277818 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04087389 0,112649 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04087389 0,11252011 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04087389 0,11239151 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04087389 0,11226321 ! adult feeding behavior GO:0008343 9 7 0,000 0,04087389 0,1121352 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04087389 0,11200749 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04087389 0,11188006 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04087389 0,11175292 ! muscle adaptation GO:0043500 14 7 0,000 0,04087389 0,11162608 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04087389 0,11149952 ! retina homeostasis GO:0001895 12 7 0,000 0,04087389 0,11137324 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04087389 0,11124726 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04087389 0,11112155 ! protein prenylation GO:0018342 18 7 0,000 0,04087389 0,11099613 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04087389 0,110871 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04087389 0,11074614 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04087389 0,11062157 ! chloride transport GO:0006821 90 55 1,000 0,04247561 0,11482732 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04247561 0,11469844 ! aging GO:0007568 103 55 1,000 0,04247561 0,11456986 ! heart morphogenesis GO:0003007 97 55 1,000 0,04247561 0,11444156 ! RNA elongation GO:0006354 79 55 1,000 0,04247561 0,11431355 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04388056 0,1179627 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04388056 0,11783104 ! muscle fiber development GO:0048747 112 57 1,000 0,04530262 0,12151406 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,04530262 0,12137875 ! lipid modification GO:0030258 97 57 1,000 0,04530262 0,12124373 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,04530262 0,12110902 ! maintenance of location GO:0051235 118 57 1,000 0,04530262 0,1209746 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04657577 0,12423647 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04657577 0,12409889 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04657577 0,12396161 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04657577 0,12382463 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04657577 0,12368796 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04657577 0,12355159 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04657577 0,12341552 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04657577 0,12327975 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04657577 0,12314428 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04657577 0,1230091 ! meiotic prophase I GO:0007128 13 8 0,000 0,04657577 0,12287423 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04657577 0,12273964 ! oligopeptide transport GO:0006857 15 8 0,000 0,04657577 0,12260536 ! UTP metabolic process GO:0046051 8 8 0,000 0,04657577 0,12247136 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04657577 0,12233766 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04657577 0,12220425 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04657577 0,12207113 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04657577 0,1219383 ! succinate metabolic process GO:0006105 14 8 0,000 0,04657577 0,12180576 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04657577 0,1216735 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04657577 0,12154153 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04657577 0,12140985 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04657577 0,12127846 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04657577 0,12114735 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04657577 0,12101652 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04657577 0,12088597 ! reflex GO:0060004 16 8 0,000 0,04657577 0,12075571 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04657577 0,12062572 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04657577 0,12049602 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04657577 0,12036659 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04657577 0,12023744 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04657577 0,12010857 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04657577 0,11997997 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04657577 0,11985165 ! pigment granule organization GO:0048753 16 8 0,000 0,04657577 0,11972361 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04657577 0,11959583 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04657577 0,11946833 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04657577 0,1193411 ! histidine metabolic process GO:0006547 16 8 0,000 0,04657577 0,11921414 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04657577 0,11908745 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04657577 0,11896103 ! glycine catabolic process GO:0006546 13 8 0,000 0,04657577 0,11883488 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04657577 0,118709 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04657577 0,11858338 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04657577 0,11845803 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04657577 0,11833294 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04657577 0,11820812 ! melanin metabolic process GO:0006582 15 8 0,000 0,04657577 0,11808356 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04657577 0,11795926 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04657577 0,11783522 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04657577 0,11771144 ! macrophage activation GO:0042116 12 8 0,000 0,04657577 0,11758793 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04657577 0,11746467 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04657577 0,11734167 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04657577 0,11721893 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04657577 0,11709644 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04657577 0,11697421 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04657577 0,11685224 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04657577 0,11673052 ! osteoblast development GO:0002076 16 8 0,000 0,04657577 0,11660905 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04657577 0,11648783 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04657577 0,11636687 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04657577 0,11624616 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04657577 0,11612569 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04657577 0,11600548 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04657577 0,11588552 ! response to UV-B GO:0010224 16 8 0,000 0,04657577 0,1157658 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04657577 0,11564633 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04657577 0,11552711 ! intermediate filament organization GO:0045109 12 8 0,000 0,04657577 0,11540813 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04657577 0,1152894 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04657577 0,11517091 ! cellular extravasation GO:0045123 12 8 0,000 0,04657577 0,11505266 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04657577 0,11493466 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04657577 0,1148169 ! response to antibiotic GO:0046677 11 8 0,000 0,04657577 0,11469938 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04657577 0,1145821 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04657577 0,11446506 ! DNA topological change GO:0006265 12 8 0,000 0,04657577 0,11434826 ! response to tropane GO:0014073 15 8 0,000 0,04657577 0,1142317 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04657577 0,11411537 ! melanosome transport GO:0032402 13 8 0,000 0,04657577 0,11399928 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04657577 0,11388343 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04657577 0,11376781 ! mast cell activation GO:0045576 14 8 0,000 0,04657577 0,11365243 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04657577 0,11353728 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04657577 0,11342236 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04657577 0,11330768 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04657577 0,11319323 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04657577 0,11307901 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04657577 0,11296501 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04657577 0,11285125 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04657577 0,11273772 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04657577 0,11262442 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04657577 0,11251134 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04657577 0,11239849 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04657577 0,11228587 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04657577 0,11217347 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04657577 0,11206129 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04657577 0,11194935 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04657577 0,11183762 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04657577 0,11172612 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04657577 0,11161484 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04657577 0,11150378 ! hormone catabolic process GO:0042447 17 8 0,000 0,04657577 0,11139294 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04657577 0,11128232 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04657577 0,11117192 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04657577 0,11106174 ! ATP catabolic process GO:0006200 11 8 0,000 0,04657577 0,11095178 ! blastocyst growth GO:0001832 19 8 0,000 0,04657577 0,11084203 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04657577 0,1107325 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04657577 0,11062319 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04657577 0,1105141 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04657577 0,11040522 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04657577 0,11029655 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04657577 0,1101881 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04657577 0,11007986 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04657577 0,10997183 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04657577 0,10986401 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04657577 0,10975641 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04657577 0,10964902 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04657577 0,10954183 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04657577 0,10943486 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04657577 0,10932809 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04657577 0,10922153 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04657577 0,10911518 ! regulation of endocytosis GO:0030100 91 58 1,000 0,04674156 0,10939709 ! kidney development GO:0001822 122 60 1,000 0,04966907 0,11613584 ! mesoderm development GO:0007498 119 61 1,000 0,05115714 0,11949911 ! axon extension GO:0048675 15 9 0,000 0,05224394 0,12191941 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05224394 0,12180127 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05224394 0,12168336 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05224394 0,12156568 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05224394 0,12144822 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05224394 0,121331 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05224394 0,12121399 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05224394 0,12109722 ! phosphate transport GO:0006817 19 9 0,000 0,05224394 0,12098067 ! reproductive behavior GO:0019098 19 9 0,000 0,05224394 0,12086434 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05224394 0,12074823 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05224394 0,12063235 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05224394 0,12051669 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05224394 0,12040126 ! GTP metabolic process GO:0046039 9 9 0,000 0,05224394 0,12028604 ! RNA methylation GO:0001510 15 9 0,000 0,05224394 0,12017104 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05224394 0,12005627 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05224394 0,11994171 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05224394 0,11982737 ! artery development GO:0060840 24 9 0,000 0,05224394 0,11971325 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05224394 0,11959935 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05224394 0,11948566 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05224394 0,11937219 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05224394 0,11925893 ! chemosensory behavior GO:0007635 20 9 0,000 0,05224394 0,11914589 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05224394 0,11903306 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05224394 0,11892045 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05224394 0,11880805 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05224394 0,11869586 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05224394 0,11858388 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05224394 0,11847211 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05224394 0,11836056 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05224394 0,11824921 ! protein targeting to ER GO:0045047 22 9 0,000 0,05224394 0,11813808 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05224394 0,11802715 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05224394 0,11791643 ! T cell selection GO:0045058 23 9 0,000 0,05224394 0,11780592 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05224394 0,11769561 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05224394 0,11758551 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05224394 0,11747562 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05224394 0,11736593 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05224394 0,11725645 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05224394 0,11714717 ! mannose metabolic process GO:0006013 13 9 0,000 0,05224394 0,11703809 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05224394 0,11692922 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05224394 0,11682055 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05224394 0,11671208 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05224394 0,11660381 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05224394 0,11649575 ! ruffle organization GO:0031529 15 9 0,000 0,05224394 0,11638788 ! retinol metabolic process GO:0042572 18 9 0,000 0,05224394 0,11628021 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05224394 0,11617275 ! behavioral fear response GO:0001662 22 9 0,000 0,05224394 0,11606548 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05224394 0,11595841 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05224394 0,11585153 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05224394 0,11574485 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05224394 0,11563837 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05224394 0,11553209 ! segment specification GO:0007379 13 9 0,000 0,05224394 0,115426 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05224394 0,1153201 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05224394 0,1152144 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05224394 0,11510889 ! response to amine stimulus GO:0014075 13 9 0,000 0,05224394 0,11500358 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05224394 0,11489846 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05224394 0,11479353 ! erythrocyte development GO:0048821 15 9 0,000 0,05224394 0,11468879 ! gas homeostasis GO:0033483 16 9 0,000 0,05224394 0,11458424 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05224394 0,11447988 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05224394 0,11437572 ! renal water homeostasis GO:0003091 14 9 0,000 0,05224394 0,11427174 ! postreplication repair GO:0006301 22 9 0,000 0,05224394 0,11416795 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05224394 0,11406435 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05224394 0,11396094 ! icosanoid secretion GO:0032309 15 9 0,000 0,05224394 0,11385771 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05224394 0,11375467 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05224394 0,11365182 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05224394 0,11354915 ! regulation of cell division GO:0051302 15 9 0,000 0,05224394 0,11344667 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05224394 0,11334438 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05224394 0,11324226 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05224394 0,11314034 ! sterol catabolic process GO:0016127 11 9 0,000 0,05224394 0,11303859 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05224394 0,11293703 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05224394 0,11283565 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05224394 0,11273445 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05224394 0,11263343 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05224394 0,1125326 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05224394 0,11243194 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05224394 0,11233147 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05224394 0,11223117 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05224394 0,11213105 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05224394 0,11203112 ! purine base metabolic process GO:0006144 21 9 0,000 0,05224394 0,11193136 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05224394 0,11183177 ! pigment granule transport GO:0051904 17 9 0,000 0,05224394 0,11173237 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05224394 0,11163314 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05224394 0,11153408 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05224394 0,11143521 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05224394 0,1113365 ! mitochondrion localization GO:0051646 15 9 0,000 0,05224394 0,11123798 ! viral reproductive process GO:0022415 126 62 1,000 0,05266111 0,11202707 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,05266111 0,11192811 ! detection of external stimulus GO:0009581 91 63 1,000 0,05418072 0,11505633 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,05418072 0,11495487 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0578786 0,12269243 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0578786 0,12258442 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0578786 0,12247661 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0578786 0,12236898 ! synapsis GO:0007129 13 10 0,000 0,0578786 0,12226155 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0578786 0,1221543 ! N-glycan processing GO:0006491 20 10 0,000 0,0578786 0,12204724 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0578786 0,12194037 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0578786 0,12183369 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0578786 0,12172719 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0578786 0,12162088 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,0578786 0,12151475 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0578786 0,12140881 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0578786 0,12130305 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0578786 0,12119748 ! androgen metabolic process GO:0008209 17 10 0,000 0,0578786 0,12109209 ! phospholipid efflux GO:0033700 16 10 0,000 0,0578786 0,12098688 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0578786 0,12088186 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0578786 0,12077702 ! lung alveolus development GO:0048286 26 10 0,000 0,0578786 0,12067236 ! pathogenesis GO:0009405 13 10 0,000 0,0578786 0,12056788 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0578786 0,12046358 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0578786 0,12035947 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0578786 0,12025553 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0578786 0,12015177 ! endoderm development GO:0007492 16 10 0,000 0,0578786 0,12004819 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0578786 0,11994479 ! arginine catabolic process GO:0006527 13 10 0,000 0,0578786 0,11984157 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0578786 0,11973852 ! proline metabolic process GO:0006560 13 10 0,000 0,0578786 0,11963566 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0578786 0,11953296 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0578786 0,11943045 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0578786 0,11932811 ! V(D)J recombination GO:0033151 28 10 0,000 0,0578786 0,11922594 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0578786 0,11912396 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0578786 0,11902214 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0578786 0,1189205 ! B cell proliferation GO:0042100 18 10 0,000 0,0578786 0,11881903 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0578786 0,11871774 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0578786 0,11861661 ! multicellular organism growth GO:0035264 18 10 0,000 0,0578786 0,11851566 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0578786 0,11841488 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0578786 0,11831428 ! epithelial cell development GO:0002064 20 10 0,000 0,0578786 0,11821384 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0578786 0,11811357 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0578786 0,11801348 ! macroautophagy GO:0016236 17 10 0,000 0,0578786 0,11791355 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0578786 0,11781379 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0578786 0,1177142 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0578786 0,11761478 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0578786 0,11751553 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0578786 0,11741644 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0578786 0,11731753 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0578786 0,11721877 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0578786 0,11712019 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0578786 0,11702177 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0578786 0,11692351 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0578786 0,11682542 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0578786 0,1167275 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0578786 0,11662973 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0578786 0,11653214 ! response to dsRNA GO:0043331 20 10 0,000 0,0578786 0,1164347 ! DNA ligation GO:0006266 19 10 0,000 0,0578786 0,11633743 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0578786 0,11624032 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0578786 0,11614337 ! melanosome localization GO:0032400 16 10 0,000 0,0578786 0,11604659 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0578786 0,11594996 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0578786 0,1158535 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0578786 0,11575719 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0578786 0,11566105 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0578786 0,11556507 ! mRNA cleavage GO:0006379 17 10 0,000 0,0578786 0,11546924 ! protein sumoylation GO:0016925 15 10 0,000 0,0578786 0,11537357 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0578786 0,11527807 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0578786 0,11518272 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0578786 0,11508752 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0578786 0,11499249 ! salivary gland development GO:0007431 27 10 0,000 0,0578786 0,11489761 ! prophase GO:0051324 15 10 0,000 0,0578786 0,11480289 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0578786 0,11470832 ! apical protein localization GO:0045176 15 10 0,000 0,0578786 0,11461391 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0578786 0,11451966 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0578786 0,11442556 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0578786 0,11433161 ! midbrain development GO:0030901 13 10 0,000 0,0578786 0,11423782 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0578786 0,11414418 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0578786 0,1140507 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0578786 0,11395737 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0578786 0,11386419 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0578786 0,11377116 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0578786 0,11367829 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0578786 0,11358557 ! detection of calcium ion GO:0005513 23 10 0,000 0,0578786 0,11349299 ! oocyte development GO:0048599 17 10 0,000 0,0578786 0,11340057 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0578786 0,1133083 ! blastocyst formation GO:0001825 17 10 0,000 0,0578786 0,11321618 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0578786 0,11312421 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0578786 0,11303239 ! activation of innate immune response GO:0002218 12 10 0,000 0,0578786 0,11294072 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0578786 0,11284919 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0578786 0,11275782 ! response to nicotine GO:0035094 20 10 0,000 0,0578786 0,11266659 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0578786 0,11257551 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0578786 0,11248457 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0578786 0,11239379 ! localization within membrane GO:0051668 20 10 0,000 0,0578786 0,11230315 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05883114 0,1140594 ! cell projection assembly GO:0030031 120 66 1,000 0,05883114 0,11396756 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06041102 0,11693396 ! chromosome segregation GO:0007059 113 67 1,000 0,06041102 0,11683996 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,06200539 0,11982729 ! viral reproduction GO:0016032 134 68 1,000 0,06200539 0,11973112 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06347994 0,12248015 ! respiratory burst GO:0045730 17 11 0,000 0,06347994 0,12238201 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06347994 0,12228402 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06347994 0,12218619 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06347994 0,12208852 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06347994 0,12199101 ! thyroid gland development GO:0030878 26 11 0,000 0,06347994 0,12189365 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06347994 0,12179645 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06347994 0,1216994 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06347994 0,1216025 ! response to pain GO:0048265 24 11 0,000 0,06347994 0,12150576 ! T cell proliferation GO:0042098 26 11 0,000 0,06347994 0,12140918 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06347994 0,12131274 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06347994 0,12121646 ! bone resorption GO:0045453 16 11 0,000 0,06347994 0,12112034 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06347994 0,12102436 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06347994 0,12092854 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06347994 0,12083287 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06347994 0,12073735 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06347994 0,12064198 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06347994 0,12054676 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06347994 0,12045169 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06347994 0,12035677 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06347994 0,120262 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06347994 0,12016738 ! lipid digestion GO:0044241 18 11 0,000 0,06347994 0,12007291 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06347994 0,11997859 ! UV protection GO:0009650 19 11 0,000 0,06347994 0,11988441 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06347994 0,11979039 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06347994 0,11969651 ! temperature homeostasis GO:0001659 17 11 0,000 0,06347994 0,11960277 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06347994 0,11950919 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06347994 0,11941575 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06347994 0,11932246 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06347994 0,11922931 ! regulation of organ growth GO:0046620 13 11 0,000 0,06347994 0,1191363 ! pigment granule localization GO:0051875 20 11 0,000 0,06347994 0,11904345 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06347994 0,11895073 ! vasoconstriction GO:0042310 18 11 0,000 0,06347994 0,11885817 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06347994 0,11876574 ! embryonic axis specification GO:0000578 18 11 0,000 0,06347994 0,11867346 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06347994 0,11858132 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06347994 0,11848933 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06347994 0,11839747 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06347994 0,11830576 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06347994 0,1182142 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06347994 0,11812277 ! zymogen activation GO:0031638 15 11 0,000 0,06347994 0,11803149 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06347994 0,11794034 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06347994 0,11784934 ! nucleosome positioning GO:0016584 15 11 0,000 0,06347994 0,11775848 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06347994 0,11766775 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06347994 0,11757717 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06347994 0,11748673 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06347994 0,11739642 ! acid secretion GO:0046717 18 11 0,000 0,06347994 0,11730625 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06347994 0,11721623 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06347994 0,11712634 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06347994 0,11703658 ! oocyte differentiation GO:0009994 18 11 0,000 0,06347994 0,11694697 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06347994 0,11685749 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06347994 0,11676815 ! cholesterol efflux GO:0033344 19 11 0,000 0,06347994 0,11667895 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06347994 0,11658988 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06347994 0,11650095 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06347994 0,11641215 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06347994 0,11632349 ! embryonic gut development GO:0048566 15 11 0,000 0,06347994 0,11623496 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06347994 0,11614657 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06347994 0,11605832 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06347994 0,11597019 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06347994 0,1158822 ! defense response to fungus GO:0050832 13 11 0,000 0,06347994 0,11579435 ! developmental induction GO:0031128 19 11 0,000 0,06347994 0,11570662 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06347994 0,11561903 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06347994 0,11553158 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06347994 0,11544425 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06347994 0,11535706 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06347994 0,11526999 ! nucleus localization GO:0051647 19 11 0,000 0,06347994 0,11518306 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06347994 0,11509626 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06361403 0,11525253 ! reproductive structure development GO:0048608 113 71 1,000 0,06687321 0,12106618 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06852331 0,12396022 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06904817 0,12481585 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06904817 0,12472215 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06904817 0,12462858 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06904817 0,12453516 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06904817 0,12444187 ! cartilage condensation GO:0001502 20 12 0,000 0,06904817 0,12434873 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06904817 0,12425572 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06904817 0,12416286 ! protein complex disassembly GO:0043241 27 12 0,000 0,06904817 0,12407013 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06904817 0,12397754 ! hippocampus development GO:0021766 26 12 0,000 0,06904817 0,12388509 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06904817 0,12379277 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06904817 0,1237006 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06904817 0,12360856 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06904817 0,12351665 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06904817 0,12342489 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06904817 0,12333326 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06904817 0,12324177 ! drug transport GO:0015893 16 12 0,000 0,06904817 0,12315041 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06904817 0,12305919 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06904817 0,1229681 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06904817 0,12287715 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06904817 0,12278633 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06904817 0,12269564 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06904817 0,12260509 ! forebrain cell migration GO:0021885 21 12 0,000 0,06904817 0,12251468 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06904817 0,12242439 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06904817 0,12233424 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06904817 0,12224422 ! entry into host cell GO:0030260 32 12 0,000 0,06904817 0,12215434 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06904817 0,12206459 ! monoamine transport GO:0015844 18 12 0,000 0,06904817 0,12197496 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06904817 0,12188547 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06904817 0,12179611 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06904817 0,12170689 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06904817 0,12161779 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06904817 0,12152882 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06904817 0,12143999 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06904817 0,12135128 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06904817 0,1212627 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06904817 0,12117425 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06904817 0,12108593 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06904817 0,12099774 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06904817 0,12090968 ! cranial nerve development GO:0021545 20 12 0,000 0,06904817 0,12082175 ! fucose catabolic process GO:0019317 22 12 0,000 0,06904817 0,12073394 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06904817 0,12064626 ! histone methylation GO:0016571 26 12 0,000 0,06904817 0,12055871 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06904817 0,12047128 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06904817 0,12038399 ! gland morphogenesis GO:0022612 29 12 0,000 0,06904817 0,12029681 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06904817 0,12020977 ! T cell homeostasis GO:0043029 25 12 0,000 0,06904817 0,12012285 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06904817 0,12003606 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06904817 0,11994939 ! spleen development GO:0048536 22 12 0,000 0,06904817 0,11986284 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06904817 0,11977642 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06904817 0,11969013 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06904817 0,11960396 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06904817 0,11951791 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06904817 0,11943199 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06904817 0,11934619 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06904817 0,11926052 ! response to cold GO:0009409 17 12 0,000 0,06904817 0,11917496 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06904817 0,11908953 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06904817 0,11900423 ! learning or memory GO:0007611 147 73 1,000 0,0701868 0,12088005 ! axon guidance GO:0007411 139 73 1,000 0,0701868 0,12079359 ! meiosis GO:0007126 121 74 1,000 0,07186345 0,12359075 GO:0051327|M phase of meiotic cell cycle, ! eye development GO:0001654 143 74 1,000 0,07186345 0,12350247 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,07355305 0,12631595 ! meiotic cell cycle GO:0051321 122 75 1,000 0,07355305 0,12622585 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07458348 0,12790296 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07458348 0,12781186 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07458348 0,12772089 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07458348 0,12763005 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07458348 0,12753934 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07458348 0,12744875 ! lipid localization GO:0010876 28 13 0,000 0,07458348 0,1273583 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07458348 0,12726798 ! organelle fusion GO:0048284 32 13 0,000 0,07458348 0,12717778 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07458348 0,12708771 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07458348 0,12699777 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07458348 0,12690795 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07458348 0,12681827 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07458348 0,1267287 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07458348 0,12663927 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07458348 0,12654996 ! methionine metabolic process GO:0006555 27 13 0,000 0,07458348 0,12646078 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07458348 0,12637172 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07458348 0,12628279 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07458348 0,12619398 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07458348 0,1261053 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07458348 0,12601675 ! response to X-ray GO:0010165 25 13 0,000 0,07458348 0,12592831 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07458348 0,12584 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07458348 0,12575182 ! exocrine system development GO:0035272 32 13 0,000 0,07458348 0,12566376 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07458348 0,12557582 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07458348 0,125488 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07458348 0,12540031 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07458348 0,12531274 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07458348 0,12522529 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07458348 0,12513797 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07458348 0,12505076 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07458348 0,12496368 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07458348 0,12487672 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07458348 0,12478988 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07458348 0,12470316 ! ribosome assembly GO:0042255 17 13 0,000 0,07458348 0,12461656 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,07458348 0,12453008 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07458348 0,12444372 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07458348 0,12435748 ! chromatin silencing GO:0006342 26 13 0,000 0,07458348 0,12427136 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07458348 0,12418536 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07458348 0,12409948 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07458348 0,12401372 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07458348 0,12392807 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07458348 0,12384254 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07458348 0,12375714 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07458348 0,12367184 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07458348 0,12358667 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07458348 0,12350161 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07458348 0,12341668 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07458348 0,12333185 ! embryonic placenta development GO:0001892 23 13 0,000 0,07458348 0,12324715 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07458348 0,12316256 ! insulin secretion GO:0030073 23 13 0,000 0,07458348 0,12307808 ! acrosome reaction GO:0007340 18 13 0,000 0,07458348 0,12299373 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07697028 0,12684281 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,07869749 0,12960039 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,07869749 0,12951174 ! rRNA transcription GO:0009303 25 14 0,000 0,08008605 0,1317068 ! lactation GO:0007595 26 14 0,000 0,08008605 0,13161683 ! reproductive cellular process GO:0048610 20 14 0,000 0,08008605 0,13152699 ! tRNA modification GO:0006400 20 14 0,000 0,08008605 0,13143727 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08008605 0,13134768 ! water transport GO:0006833 21 14 0,000 0,08008605 0,1312582 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08008605 0,13116885 ! non-recombinational repair GO:0000726 25 14 0,000 0,08008605 0,13107962 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08008605 0,13099051 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08008605 0,13090152 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08008605 0,13081266 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08008605 0,13072391 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08008605 0,13063528 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08008605 0,13054678 ! palate development GO:0060021 31 14 0,000 0,08008605 0,13045839 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08008605 0,13037012 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08008605 0,13028198 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08008605 0,13019395 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08008605 0,13010604 ! arginine metabolic process GO:0006525 17 14 0,000 0,08008605 0,13001825 ! regulation of heart rate GO:0002027 24 14 0,000 0,08008605 0,12993058 ! organic alcohol transport GO:0015850 29 14 0,000 0,08008605 0,12984302 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08008605 0,12975559 ! embryo implantation GO:0007566 30 14 0,000 0,08008605 0,12966827 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08008605 0,12958107 ! L-amino acid transport GO:0015807 30 14 0,000 0,08008605 0,12949398 ! bone mineralization GO:0030282 17 14 0,000 0,08008605 0,12940701 ! stem cell development GO:0048864 43 14 0,000 0,08008605 0,12932016 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08008605 0,12923343 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08008605 0,12914681 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08008605 0,12906031 ! cerebellum development GO:0021549 21 14 0,000 0,08008605 0,12897393 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08008605 0,12888766 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08008605 0,1288015 ! response to gamma radiation GO:0010332 28 14 0,000 0,08008605 0,12871546 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08008605 0,12862954 ! cofactor transport GO:0051181 26 14 0,000 0,08008605 0,12854373 ! NADP metabolic process GO:0006739 24 14 0,000 0,08008605 0,12845803 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08008605 0,12837245 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08008605 0,12828698 ! intestinal absorption GO:0050892 25 14 0,000 0,08008605 0,12820163 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08008605 0,12811639 ! oxygen transport GO:0015671 21 14 0,000 0,08008605 0,12803126 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08008605 0,12794624 ! male genitalia development GO:0030539 24 14 0,000 0,08008605 0,12786134 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08008605 0,12777655 ! regulation of axon extension GO:0030516 37 14 0,000 0,08008605 0,12769188 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08008605 0,12760731 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,08218807 0,13086996 ! response to metal ion GO:0010038 140 80 1,000 0,08218807 0,1307834 ! inorganic anion transport GO:0015698 138 80 1,000 0,08218807 0,13069696 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08555609 0,13596299 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08555609 0,13587324 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08555609 0,13578361 ! superoxide anion generation GO:0042554 20 15 0,000 0,08555609 0,13569411 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,08555609 0,13560472 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08555609 0,13551544 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08555609 0,13542629 ! copper ion transport GO:0006825 20 15 0,000 0,08555609 0,13533725 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08555609 0,13524833 ! sulfate transport GO:0008272 23 15 0,000 0,08555609 0,13515953 ! response to cAMP GO:0051591 22 15 0,000 0,08555609 0,13507084 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08555609 0,13498227 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08555609 0,13489381 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08555609 0,13480547 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08555609 0,13471725 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08555609 0,13462914 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08555609 0,13454115 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08555609 0,13445327 ! pituitary gland development GO:0021983 29 15 0,000 0,08555609 0,13436551 ! vesicle coating GO:0006901 33 15 0,000 0,08555609 0,13427786 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08555609 0,13419033 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08555609 0,13410291 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08555609 0,1340156 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08555609 0,13392841 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08555609 0,13384133 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08555609 0,13375436 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08555609 0,13366751 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08555609 0,13358077 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08555609 0,13349414 ! histone deacetylation GO:0016575 20 15 0,000 0,08555609 0,13340762 ! tissue regeneration GO:0042246 26 15 0,000 0,08555609 0,13332122 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08555609 0,13323493 ! water homeostasis GO:0030104 27 15 0,000 0,08555609 0,13314874 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08555609 0,13306268 ! muscle maintenance GO:0046716 26 15 0,000 0,08555609 0,13297672 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08555609 0,13289087 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08555609 0,13280514 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08555609 0,13271951 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08555609 0,13263399 ! cell killing GO:0001906 29 15 0,000 0,08555609 0,13254859 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08555609 0,13246329 ! detection of bacterium GO:0016045 18 15 0,000 0,08555609 0,13237811 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08555609 0,13229303 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08555609 0,13220807 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08555609 0,13212321 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08555609 0,13203846 ! peptide hormone processing GO:0016486 23 15 0,000 0,08555609 0,13195382 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08572553 0,13213044 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,08572553 0,13204585 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08751133 0,13471034 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08930827 0,13738855 ! negative regulation of transport GO:0051051 153 84 1,000 0,08930827 0,13730076 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09099379 0,13980271 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09099379 0,1397135 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09099379 0,13962439 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09099379 0,13953541 ! bone remodeling GO:0046849 27 16 0,000 0,09099379 0,13944653 ! filopodium assembly GO:0046847 32 16 0,000 0,09099379 0,13935777 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09099379 0,13926912 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09099379 0,13918058 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09099379 0,13909215 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09099379 0,13900384 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09099379 0,13891564 ! startle response GO:0001964 28 16 0,000 0,09099379 0,13882755 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09099379 0,13873958 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09099379 0,13865171 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09099379 0,13856396 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09099379 0,13847631 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09099379 0,13838878 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09099379 0,13830136 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09099379 0,13821405 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09099379 0,13812685 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09099379 0,13803975 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09099379 0,13795277 ! fructose metabolic process GO:0006000 25 16 0,000 0,09099379 0,1378659 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09099379 0,13777914 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09099379 0,13769248 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09099379 0,13760594 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09099379 0,1375195 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09099379 0,13743318 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09099379 0,13734696 ! DNA replication initiation GO:0006270 27 16 0,000 0,09099379 0,13726085 ! neuron recognition GO:0008038 35 16 0,000 0,09099379 0,13717484 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09099379 0,13708895 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09099379 0,13700316 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09099379 0,13691748 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09099379 0,13683191 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,09099379 0,13674644 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09099379 0,13666108 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09099379 0,13657583 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09099379 0,13649068 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09099379 0,13640564 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09099379 0,1363207 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09099379 0,13623587 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09099379 0,13615115 ! defense response to virus GO:0051607 37 16 0,000 0,09099379 0,13606653 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09111613 0,13616485 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,09293473 0,13879638 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09476389 0,14144039 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,09476389 0,14135271 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09639933 0,14370308 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09639933 0,1436141 ! metencephalon development GO:0022037 30 17 0,000 0,09639933 0,14352523 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09639933 0,14343647 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09639933 0,14334782 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09639933 0,14325928 ! endothelial cell migration GO:0043542 28 17 0,000 0,09639933 0,14317085 ! inositol metabolic process GO:0006020 28 17 0,000 0,09639933 0,14308253 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09639933 0,14299431 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09639933 0,14290621 ! glial cell development GO:0021782 27 17 0,000 0,09639933 0,14281821 ! limbic system development GO:0021761 36 17 0,000 0,09639933 0,14273032 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09639933 0,14264254 ! adult walking behavior GO:0007628 33 17 0,000 0,09639933 0,14255487 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09639933 0,14246731 ! heart looping GO:0001947 30 17 0,000 0,09639933 0,14237985 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09639933 0,1422925 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09639933 0,14220526 ! myoblast differentiation GO:0045445 45 17 0,000 0,09639933 0,14211812 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09639933 0,14203109 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,09639933 0,14194417 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09639933 0,14185736 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09639933 0,14177065 ! glycine metabolic process GO:0006544 28 17 0,000 0,09639933 0,14168404 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09639933 0,14159754 ! NAD metabolic process GO:0019674 29 17 0,000 0,09639933 0,14151115 ! membrane budding GO:0006900 37 17 0,000 0,09639933 0,14142486 ! DNA integration GO:0015074 29 17 0,000 0,09639933 0,14133868 ! regulation of protein binding GO:0043393 33 17 0,000 0,09639933 0,1412526 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09639933 0,14116663 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09639933 0,14108076 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09639933 0,140995 ! genitalia development GO:0048806 30 17 0,000 0,09639933 0,14090934 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09639933 0,14082379 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09639933 0,14073834 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09639933 0,14065299 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09639933 0,14056774 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09639933 0,1404826 ! steroid catabolic process GO:0006706 31 17 0,000 0,09639933 0,14039756 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09639933 0,14031263 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09639933 0,1402278 ! gas transport GO:0015669 25 17 0,000 0,09639933 0,14014307 ! organic cation transport GO:0015695 31 17 0,000 0,09639933 0,14005844 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09639933 0,13997391 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,09639933 0,13988949 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09639933 0,13980517 ! microspike assembly GO:0030035 36 17 0,000 0,09639933 0,13972095 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09639933 0,13963683 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09639933 0,13955281 ! ossification GO:0001503 188 90 1,000 0,10031279 0,14513083 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,10031279 0,14504361 ! sex differentiation GO:0007548 145 90 1,000 0,10031279 0,14495649 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1017729 0,14697815 ! neuron maturation GO:0042551 42 18 0,000 0,1017729 0,14688998 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,1017729 0,14680191 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,1017729 0,14671395 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,1017729 0,1466261 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,1017729 0,14653835 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1017729 0,14645071 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1017729 0,14636317 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1017729 0,14627574 ! patterning of blood vessels GO:0001569 39 18 0,000 0,1017729 0,14618841 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1017729 0,14610119 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,1017729 0,14601407 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,1017729 0,14592705 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,1017729 0,14584014 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1017729 0,14575333 ! response to retinoic acid GO:0032526 26 18 0,000 0,1017729 0,14566662 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,1017729 0,14558002 ! response to fungus GO:0009620 21 18 0,000 0,1017729 0,14549352 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,1017729 0,14540712 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,1017729 0,14532083 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,1017729 0,14523463 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,1017729 0,14514854 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1017729 0,14506255 ! vitamin transport GO:0051180 27 18 0,000 0,1017729 0,14497667 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,1017729 0,14489088 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1017729 0,1448052 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,1017729 0,14471962 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,1017729 0,14463414 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1017729 0,14454875 ! nerve development GO:0021675 28 18 0,000 0,1017729 0,14446348 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1017729 0,1443783 ! bone development GO:0060348 189 91 1,000 0,10218228 0,14487364 ! regulation of membrane potential GO:0042391 164 93 1,000 0,10594998 0,15012701 ! protein secretion GO:0009306 39 19 0,000 0,10711469 0,15168802 ! positive regulation of translation GO:0045727 30 19 0,000 0,10711469 0,15159879 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10711469 0,15150967 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10711469 0,15142065 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10711469 0,15133174 ! skin development GO:0043588 36 19 0,000 0,10711469 0,15124293 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10711469 0,15115422 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10711469 0,15106562 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10711469 0,15097712 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10711469 0,15088873 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10711469 0,15080044 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10711469 0,15071225 ! cerebral cortex development GO:0021987 36 19 0,000 0,10711469 0,15062417 ! pigmentation during development GO:0048066 41 19 0,000 0,10711469 0,15053618 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10711469 0,15044831 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10711469 0,15036053 ! heme metabolic process GO:0042168 36 19 0,000 0,10711469 0,15027286 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10711469 0,15018528 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10711469 0,15009781 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10711469 0,15001045 ! peptide cross-linking GO:0018149 37 19 0,000 0,10711469 0,14992318 ! protein export from nucleus GO:0006611 36 19 0,000 0,10711469 0,14983602 ! heart process GO:0003015 30 19 0,000 0,10711469 0,14974895 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10711469 0,14966199 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10711469 0,14957513 ! visual learning GO:0008542 36 19 0,000 0,10711469 0,14948837 ! cellular pigmentation GO:0033059 36 19 0,000 0,10711469 0,14940171 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10711469 0,14931515 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10711469 0,14922869 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10711469 0,14914233 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10711469 0,14905607 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10711469 0,14896991 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10711469 0,14888385 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10711469 0,14879789 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10711469 0,14871203 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10711469 0,14862627 ! cilium assembly GO:0042384 37 19 0,000 0,10711469 0,1485406 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10711469 0,14845504 ! detection of stimulus GO:0051606 151 96 1,000 0,11167065 0,15468024 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11242489 0,15563538 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11242489 0,15554588 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11242489 0,15545649 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11242489 0,1553672 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11242489 0,15527801 ! response to vitamin GO:0033273 31 20 0,000 0,11242489 0,15518892 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11242489 0,15509994 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11242489 0,15501106 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11242489 0,15492228 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11242489 0,1548336 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11242489 0,15474502 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11242489 0,15465654 GO:0032392|DNA geometric change, ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11242489 0,15456817 ! body fluid secretion GO:0007589 31 20 0,000 0,11242489 0,15447989 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11242489 0,15439172 ! peptide secretion GO:0002790 35 20 0,000 0,11242489 0,15430365 ! stem cell differentiation GO:0048863 53 20 0,000 0,11242489 0,15421567 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11242489 0,1541278 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11242489 0,15404003 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11242489 0,15395236 ! sensory perception of pain GO:0019233 30 20 0,000 0,11242489 0,15386479 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11242489 0,15377731 ! diencephalon development GO:0021536 34 20 0,000 0,11242489 0,15368994 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11242489 0,15360267 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11242489 0,15351549 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11242489 0,15342841 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,11242489 0,15334144 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11242489 0,15325456 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11242489 0,15316778 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11242489 0,15308109 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11242489 0,15299451 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11242489 0,15290802 ! regulation of glucose import GO:0046324 29 20 0,000 0,11242489 0,15282163 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11242489 0,15273534 ! actin filament-based movement GO:0030048 43 20 0,000 0,11242489 0,15264915 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11242489 0,15256305 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11242489 0,15247705 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11242489 0,15239115 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11242489 0,15230535 ! regulation of protein localization GO:0032880 176 97 1,000 0,11359527 0,15380429 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,1174701 0,15896123 ! regulation of cell killing GO:0031341 42 21 0,000 0,11770369 0,15918779 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11770369 0,15909836 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11770369 0,15900903 ! hormone secretion GO:0046879 38 21 0,000 0,11770369 0,1589198 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11770369 0,15883067 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11770369 0,15874164 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11770369 0,1586527 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11770369 0,15856387 ! axis specification GO:0009798 38 21 0,000 0,11770369 0,15847514 ! ovarian follicle development GO:0001541 35 21 0,000 0,11770369 0,15838651 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11770369 0,15829798 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11770369 0,15820954 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11770369 0,15812121 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11770369 0,15803297 ! cell aging GO:0007569 44 21 0,000 0,11770369 0,15794483 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11770369 0,15785679 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11770369 0,15776885 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11770369 0,157681 ! cytolysis GO:0019835 24 21 0,000 0,11770369 0,15759325 ! vasodilation GO:0042311 39 21 0,000 0,11770369 0,15750561 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11770369 0,15741805 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11770369 0,1573306 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11770369 0,15724324 ! oogenesis GO:0048477 36 21 0,000 0,11770369 0,15715598 ! DNA modification GO:0006304 34 21 0,000 0,11770369 0,15706882 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,11770369 0,15698175 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,11770369 0,15689478 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11770369 0,15680791 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11770369 0,15672113 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11770369 0,15663445 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11770369 0,15654786 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11770369 0,15646137 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11770369 0,15637497 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11770369 0,15628867 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11770369 0,15620247 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11770369 0,15611636 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11770369 0,15603035 ! gut development GO:0048565 39 21 0,000 0,11770369 0,15594443 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12295127 0,16280723 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12295127 0,16271768 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12295127 0,16262823 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12295127 0,16253887 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12295127 0,16244961 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,12295127 0,16236045 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12295127 0,16227139 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12295127 0,16218243 ! regeneration GO:0031099 41 22 0,000 0,12295127 0,16209356 ! keratinization GO:0031424 28 22 0,000 0,12295127 0,16200479 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12295127 0,16191612 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12295127 0,16182754 ! sensory perception of taste GO:0050909 28 22 0,000 0,12295127 0,16173906 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12295127 0,16165068 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12295127 0,1615624 ! vacuolar transport GO:0007034 36 22 0,000 0,12295127 0,16147421 ! lysosome organization GO:0007040 41 22 0,000 0,12295127 0,16138611 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12295127 0,16129812 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12295127 0,16121022 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12295127 0,16112241 ! fucose metabolic process GO:0006004 39 22 0,000 0,12295127 0,1610347 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12295127 0,16094709 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12295127 0,16085957 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12295127 0,16077214 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12295127 0,16068482 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12295127 0,16059758 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12295127 0,16051044 ! sarcomere organization GO:0045214 30 22 0,000 0,12295127 0,1604234 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12295127 0,16033645 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12295127 0,16024959 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12295127 0,16016283 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,1281678 0,16686782 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1281678 0,16677758 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1281678 0,16668743 ! gluconeogenesis GO:0006094 33 23 0,000 0,1281678 0,16659737 ! viral genome replication GO:0019079 41 23 0,000 0,1281678 0,16650742 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1281678 0,16641756 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1281678 0,1663278 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1281678 0,16623813 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1281678 0,16614857 ! visual behavior GO:0007632 42 23 0,000 0,1281678 0,16605909 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1281678 0,16596972 ! response to ethanol GO:0045471 46 23 0,000 0,1281678 0,16588044 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1281678 0,16579126 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,1281678 0,16570217 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1281678 0,16561318 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1281678 0,16552428 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1281678 0,16543548 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1281678 0,16534678 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1281678 0,16525817 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1281678 0,16516965 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1281678 0,16508123 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1281678 0,1649929 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1281678 0,16490467 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1281678 0,16481654 ! fatty acid transport GO:0015908 44 23 0,000 0,1281678 0,16472849 ! platelet activation GO:0030168 37 23 0,000 0,1281678 0,16464054 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1281678 0,16455269 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1281678 0,16446493 ! hormone transport GO:0009914 40 23 0,000 0,1281678 0,16437726 ! cell-cell recognition GO:0009988 25 23 0,000 0,1281678 0,16428968 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1281678 0,1642022 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1281678 0,16411481 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1281678 0,16402752 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1281678 0,16394032 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,13335349 0,17048273 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13335349 0,17039219 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13335349 0,17030175 ! vesicle docking GO:0048278 47 24 0,000 0,13335349 0,1702114 ! spinal cord development GO:0021510 47 24 0,000 0,13335349 0,17012115 ! vacuole organization GO:0007033 43 24 0,000 0,13335349 0,170031 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13335349 0,16994094 ! digestive system process GO:0022600 39 24 0,000 0,13335349 0,16985098 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13335349 0,16976111 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13335349 0,16967133 ! regulation of behavior GO:0050795 43 24 0,000 0,13335349 0,16958166 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13335349 0,16949207 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13335349 0,16940258 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13335349 0,16931319 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13335349 0,16922389 ! membrane depolarization GO:0051899 39 24 0,000 0,13335349 0,16913468 ! pallium development GO:0021543 49 24 0,000 0,13335349 0,16904557 ! pentose metabolic process GO:0019321 35 24 0,000 0,13335349 0,16895655 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,13335349 0,16886763 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,13335349 0,1687788 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13335349 0,16869006 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13335349 0,16860141 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13335349 0,16851286 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13335349 0,16842441 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13335349 0,16833604 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13335349 0,16824777 ! regulation of amine transport GO:0051952 40 24 0,000 0,13335349 0,16815959 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,1385085 0,17456859 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,1385085 0,1744772 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,1385085 0,1743859 ! phototransduction GO:0007602 33 25 0,000 0,1385085 0,17429469 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,1385085 0,17420358 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,1385085 0,17411256 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,1385085 0,17402164 ! sperm motility GO:0030317 31 25 0,000 0,1385085 0,17393082 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,1385085 0,17384009 ! chromosome condensation GO:0030261 45 25 0,000 0,1385085 0,17374945 ! osteoblast differentiation GO:0001649 60 25 0,000 0,1385085 0,17365891 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,1385085 0,17356846 ! neural crest cell development GO:0014032 54 25 0,000 0,1385085 0,17347811 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,1385085 0,17338785 ! negative regulation of cell development GO:0010721 73 25 0,000 0,1385085 0,17329768 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,1385085 0,17320761 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,1385085 0,17311763 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,1385085 0,17302775 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,1385085 0,17293796 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,1385085 0,17284826 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,1385085 0,17275866 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,1385085 0,17266914 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,1385085 0,17257972 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,1385085 0,1724904 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,1385085 0,17240116 ! telomere organization GO:0032200 43 25 0,000 0,1385085 0,17231202 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,1385085 0,17222297 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,1385085 0,17213401 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14363302 0,17841045 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14363302 0,17831839 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14363302 0,17822642 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14363302 0,17813455 ! initiation of viral infection GO:0019059 57 26 0,000 0,14363302 0,17804278 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14363302 0,1779511 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14363302 0,17785951 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14363302 0,17776802 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14363302 0,17767663 ! molting cycle process GO:0022404 50 26 0,000 0,14363302 0,17758532 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,14363302 0,17749411 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14363302 0,177403 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14363302 0,17731197 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14363302 0,17722104 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14363302 0,17713021 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,14363302 0,17703946 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14363302 0,17694881 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14363302 0,17685826 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14363302 0,17676779 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,14363302 0,17667742 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14363302 0,17658714 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14363302 0,17649695 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14363302 0,17640686 ! blastocyst development GO:0001824 49 26 0,000 0,14363302 0,17631685 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14363302 0,17622694 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14363302 0,17613712 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14363302 0,17604739 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,14872722 0,18219842 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14872722 0,18210569 ! iron ion transport GO:0006826 59 27 0,000 0,14872722 0,18201307 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,14872722 0,18192053 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14872722 0,18182809 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14872722 0,18173575 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14872722 0,1816435 ! fat cell differentiation GO:0045444 50 27 0,000 0,14872722 0,18155134 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14872722 0,18145927 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14872722 0,1813673 ! autophagy GO:0006914 41 27 0,000 0,14872722 0,18127543 ! male gonad development GO:0008584 44 27 0,000 0,14872722 0,18118364 ! response to toxin GO:0009636 47 27 0,000 0,14872722 0,18109195 ! primary neural tube formation GO:0014020 51 27 0,000 0,14872722 0,18100035 ! base-excision repair GO:0006284 41 27 0,000 0,14872722 0,18090884 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14872722 0,18081743 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14872722 0,18072611 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14872722 0,18063488 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14872722 0,18054374 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15379129 0,18659699 ! circadian rhythm GO:0007623 50 28 0,000 0,15379129 0,18650294 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15379129 0,18640899 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15379129 0,18631513 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,15379129 0,18622136 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15379129 0,18612769 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,15379129 0,18603411 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15379129 0,18594062 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15379129 0,18584723 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15379129 0,18575394 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15379129 0,18566073 ! synaptogenesis GO:0007416 42 28 0,000 0,15379129 0,18556762 ! lipid oxidation GO:0034440 43 28 0,000 0,15379129 0,18547461 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15379129 0,18538168 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15379129 0,18528885 ! translational initiation GO:0006413 65 29 0,000 0,1588254 0,19125821 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,1588254 0,19116254 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1588254 0,19106696 ! regulation of pH GO:0006885 43 29 0,000 0,1588254 0,19097147 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1588254 0,19087608 ! catechol metabolic process GO:0009712 54 29 0,000 0,1588254 0,19078078 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,1588254 0,19068558 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,1588254 0,19059048 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,1588254 0,19049547 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,1588254 0,19040055 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,1588254 0,19030573 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,1588254 0,19021101 ! cell fate determination GO:0001709 60 29 0,000 0,1588254 0,19011637 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,1588254 0,19002183 ! detection of light stimulus GO:0009583 38 29 0,000 0,1588254 0,18992739 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,1588254 0,18983304 ! tissue homeostasis GO:0001894 48 29 0,000 0,1588254 0,18973878 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,1588254 0,18964462 ! phenol metabolic process GO:0018958 55 30 0,000 0,16382973 0,19552298 ! zinc ion transport GO:0006829 45 30 0,000 0,16382973 0,19542604 ! membrane docking GO:0022406 61 30 0,000 0,16382973 0,1953292 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16382973 0,19523245 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16382973 0,1951358 ! acute-phase response GO:0006953 49 30 0,000 0,16382973 0,19503925 ! myofibril assembly GO:0030239 47 30 0,000 0,16382973 0,19494279 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16382973 0,19484643 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16382973 0,19475016 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,16382973 0,19465399 ! phospholipid transport GO:0015914 51 30 0,000 0,16382973 0,19455791 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16382973 0,19446193 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16382973 0,19436604 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16382973 0,19427024 ! eye morphogenesis GO:0048592 60 30 0,000 0,16382973 0,19417454 ! response to heat GO:0009408 50 30 0,000 0,16382973 0,19407894 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16880445 0,19987377 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16880445 0,19977546 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16880445 0,19967724 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16880445 0,19957912 GO:0009799|determination of symmetry, ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16880445 0,19948109 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16880445 0,19938317 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16880445 0,19928533 ! ovulation cycle process GO:0022602 49 31 0,000 0,16880445 0,1991876 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16880445 0,19908996 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16880445 0,19899241 ! peptide transport GO:0015833 55 31 0,000 0,16880445 0,19889496 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16880445 0,19879761 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16880445 0,19870035 ! natural killer cell activation GO:0030101 45 31 0,000 0,16880445 0,19860318 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16880445 0,19850611 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16880445 0,19840914 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16880445 0,19831226 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16880445 0,19821548 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17374974 0,20392287 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17374974 0,20382344 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17374974 0,20372411 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17374974 0,20362488 ! cholesterol transport GO:0030301 56 32 0,000 0,17374974 0,20352574 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17374974 0,2034267 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17374974 0,20332776 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17374974 0,20322891 ! response to ionizing radiation GO:0010212 65 32 0,000 0,17374974 0,20313016 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17374974 0,20303151 ! muscle cell development GO:0055001 49 32 0,000 0,17374974 0,20293295 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17374974 0,20283449 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17374974 0,20273612 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,17374974 0,20263785 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,17374974 0,20253967 ! ovulation cycle GO:0042698 51 32 0,000 0,17374974 0,20244159 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17374974 0,2023436 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,17374974 0,20224571 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17374974 0,20214791 ! gene silencing GO:0016458 65 32 0,000 0,17374974 0,20205021 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17866577 0,20766659 ! post-embryonic development GO:0009791 69 33 0,000 0,17866577 0,20756632 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,17866577 0,20746614 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17866577 0,20736606 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17866577 0,20726608 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17866577 0,20716619 ! sterol transport GO:0015918 57 33 0,000 0,17866577 0,2070664 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,17866577 0,20696671 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17866577 0,20686711 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17866577 0,2067676 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17866577 0,2066682 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18355272 0,21221905 ! glial cell differentiation GO:0010001 63 34 0,000 0,18355272 0,21211712 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18355272 0,21201528 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18355272 0,21191355 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,18355272 0,21181191 ! mismatch repair GO:0006298 46 34 0,000 0,18355272 0,21171037 ! spermatid development GO:0007286 63 34 0,000 0,18355272 0,21160893 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18355272 0,21150758 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18355272 0,21140634 ! placenta development GO:0001890 53 34 0,000 0,18355272 0,21130518 ! regulation of muscle development GO:0048634 70 35 0,000 0,18841074 0,216794 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18841074 0,21669037 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18841074 0,21658684 ! odontogenesis GO:0042476 66 35 0,000 0,18841074 0,21648341 ! female gonad development GO:0008585 58 35 0,000 0,18841074 0,21638007 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18841074 0,21627684 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,18841074 0,2161737 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,18841074 0,21607066 ! cytokine production GO:0001816 59 35 0,000 0,18841074 0,21596772 ! neural tube formation GO:0001841 67 35 0,000 0,18841074 0,21586488 ! vesicle localization GO:0051648 64 35 0,000 0,18841074 0,21576214 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19324003 0,22118721 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19324003 0,22108203 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19324003 0,22097695 ! positive regulation of cell development GO:0010720 80 36 0,000 0,19324003 0,22087197 ! regulation of proteolysis GO:0030162 72 36 0,000 0,19324003 0,2207671 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19324003 0,22066232 ! aerobic respiration GO:0009060 55 36 0,000 0,19324003 0,22055764 ! embryonic organ development GO:0048568 57 36 0,000 0,19324003 0,22045306 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19324003 0,22034858 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19804073 0,22571578 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19804073 0,2256089 ! meiosis I GO:0007127 65 37 0,000 0,19804073 0,22550213 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19804073 0,22539546 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19804073 0,22528889 ! organic anion transport GO:0015711 68 37 0,000 0,19804073 0,22518242 ! tissue remodeling GO:0048771 76 37 0,000 0,19804073 0,22507605 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19804073 0,22496978 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19804073 0,22486362 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19804073 0,22475755 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19804073 0,22465158 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,19804073 0,22454571 ! pigment metabolic process GO:0042440 80 37 0,000 0,19804073 0,22443995 ! spermatid differentiation GO:0048515 66 37 0,000 0,19804073 0,22433428 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20281303 0,22963207 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20281303 0,22952406 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20281303 0,22941615 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20281303 0,22930834 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,20281303 0,22920063 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,20281303 0,22909303 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20281303 0,22898552 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,20281303 0,22887812 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20281303 0,22877082 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,20281303 0,22866361 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20281303 0,22855651 ! glucan metabolic process GO:0044042 62 38 0,000 0,20281303 0,22844951 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,20755709 0,23368383 ! learning GO:0007612 77 39 0,000 0,20755709 0,23357453 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20755709 0,23346533 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,20755709 0,23335624 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20755709 0,23324724 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20755709 0,23313835 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20755709 0,23302956 ! RNA modification GO:0009451 57 39 0,000 0,20755709 0,23292087 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20755709 0,23281228 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21227307 0,23799115 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21227307 0,2378803 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21227307 0,23776955 ! feeding behavior GO:0007631 59 40 0,000 0,21227307 0,23765891 ! mesenchymal cell development GO:0014031 87 40 0,000 0,21227307 0,23754837 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21227307 0,23743794 ! cytokinesis GO:0000910 72 40 0,000 0,21227307 0,2373276 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21696114 0,24245634 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,21696114 0,24234378 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,21696114 0,24223132 ! gliogenesis GO:0042063 88 41 0,000 0,21696114 0,24211897 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21696114 0,24200672 ! T cell differentiation GO:0030217 81 41 0,000 0,21696114 0,24189458 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,21696114 0,24178254 ! female gamete generation GO:0007292 61 41 0,000 0,21696114 0,2416706 ! polyol metabolic process GO:0019751 66 41 0,000 0,21696114 0,24155877 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,22162146 0,24663332 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,22162146 0,2465193 ! regulation of tube size GO:0035150 71 42 0,000 0,22162146 0,24640538 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22162146 0,24629157 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,22162146 0,24617786 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22162146 0,24606426 ! neuron migration GO:0001764 79 42 0,000 0,22162146 0,24595076 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22162146 0,24583736 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,22162146 0,24572408 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22625421 0,25074511 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22625421 0,25062966 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22625421 0,25051432 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,22625421 0,25039909 ! glucose transport GO:0015758 65 43 0,000 0,22625421 0,25028397 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22625421 0,25016895 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,22625421 0,25005403 ! striated muscle contraction GO:0006941 77 43 0,000 0,22625421 0,24993922 ! phagocytosis GO:0006909 90 43 0,000 0,22625421 0,24982452 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22625421 0,24970992 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23085953 0,25467585 ! hexose transport GO:0008645 67 44 0,000 0,23085953 0,25455914 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23085953 0,25444253 ! male sex differentiation GO:0046661 76 44 0,000 0,23085953 0,25432602 ! double-strand break repair GO:0006302 81 44 0,000 0,23085953 0,25420963 ! biopolymer methylation GO:0043414 84 44 0,000 0,23085953 0,25409334 ! B cell differentiation GO:0030183 107 44 0,000 0,23085953 0,25397715 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23085953 0,25386108 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,23085953 0,2537451 ! developmental growth GO:0048589 82 44 0,000 0,23085953 0,25362924 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,2354376 0,25854078 ! glycolysis GO:0006096 65 45 0,000 0,2354376 0,25842284 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,2354376 0,258305 ! leukocyte migration GO:0050900 68 45 0,000 0,2354376 0,25818726 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,2354376 0,25806964 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,2354376 0,25795212 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,2354376 0,25783471 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,2354376 0,25771741 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,2354376 0,25760021 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23998856 0,26246022 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,23998856 0,26234097 ! positive regulation of defense response GO:0031349 76 47 0,000 0,24451259 0,26716498 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,24451259 0,26704371 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24451259 0,26692255 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24451259 0,26680149 ! JNK cascade GO:0007254 91 47 0,000 0,24451259 0,26668055 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24451259 0,26655972 ! methylation GO:0032259 90 47 0,000 0,24451259 0,26643899 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,24900984 0,27121669 ! mitochondrial transport GO:0006839 82 48 0,000 0,24900984 0,27109397 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24900984 0,27097136 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24900984 0,27084886 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24900984 0,27072647 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24900984 0,27060419 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24900984 0,27048202 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,24900984 0,27035996 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25348046 0,27508976 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,25348046 0,27496573 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25348046 0,27484182 ! regulation of ion transport GO:0043269 77 49 0,000 0,25348046 0,27471802 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,25348046 0,27459433 ! response to temperature stimulus GO:0009266 76 49 0,000 0,25348046 0,27447075 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,25348046 0,27434728 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,25348046 0,27422392 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25348046 0,27410067 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 0,000 0,25792462 0,27878106 ! neuromuscular process GO:0050905 99 50 0,000 0,25792462 0,27865588 ! regulation of ossification GO:0030278 117 50 0,000 0,25792462 0,27853081 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,25792462 0,27840585 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25792462 0,27828101 ! viral infectious cycle GO:0019058 99 51 0,000 0,26234247 0,28292066 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,26234247 0,2827939 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,26234247 0,28266726 ! excretion GO:0007588 83 51 0,000 0,26234247 0,28254073 ! chromatin remodeling GO:0006338 109 51 0,000 0,26234247 0,28241431 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,26234247 0,28228801 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,26234247 0,28216182 ! vesicle organization GO:0016050 107 51 0,000 0,26234247 0,28203574 ! regulation of cell shape GO:0008360 125 51 0,000 0,26234247 0,28190978 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,26673417 0,28650108 ! membrane fusion GO:0006944 110 52 0,000 0,26673417 0,28637323 ! amino acid activation GO:0043038 92 52 0,000 0,26673417 0,2862455 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,26673417 0,28611788 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,27109986 0,29067124 ! RNA catabolic process GO:0006401 93 53 0,000 0,27109986 0,29054177 ! regulation of translational initiation GO:0006446 82 53 0,000 0,27109986 0,29041241 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,27109986 0,29028316 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27109986 0,29015403 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,27109986 0,29002502 ! cell maturation GO:0048469 100 53 0,000 0,27109986 0,28989612 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,27109986 0,28976733 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,27109986 0,28963866 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,27543971 0,29414467 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,27543971 0,29401417 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,27543971 0,29388379 ! cell recognition GO:0008037 85 54 0,000 0,27543971 0,29375352 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27543971 0,29362337 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27543971 0,29349333 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27543971 0,29336341 ! glucose catabolic process GO:0006007 82 55 0,000 0,27975386 0,29782645 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,27975386 0,29769473 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27975386 0,29756312 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,27975386 0,29743163 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,27975386 0,29730026 ! nuclear export GO:0051168 97 55 0,000 0,27975386 0,297169 ! regulation of actin filament length GO:0030832 105 56 0,000 0,28404246 0,30159143 ! sensory perception of smell GO:0007608 80 56 0,000 0,28404246 0,30145839 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28404246 0,30132547 ! proton transport GO:0015992 94 56 0,000 0,28404246 0,30119267 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,28404246 0,30105999 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,28830568 0,30544406 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,28830568 0,30530962 ! hydrogen transport GO:0006818 97 58 0,000 0,29254364 0,30966124 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,29254364 0,30952507 ! adult behavior GO:0030534 99 58 0,000 0,29254364 0,30938901 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,29254364 0,30925308 ! positive regulation of secretion GO:0051047 95 59 0,000 0,29675651 0,31356881 ! regulation of cellular component size GO:0032535 109 59 0,000 0,29675651 0,31343116 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29675651 0,31329363 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,29675651 0,31315622 ! establishment of organelle localization GO:0051656 109 59 0,000 0,29675651 0,31301893 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,30094444 0,31729725 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,30094444 0,31715826 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,30094444 0,3170194 ! regulation of heart contraction GO:0008016 110 60 0,000 0,30094444 0,31688066 ! camera-type eye development GO:0043010 116 60 0,000 0,30094444 0,31674204 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,30094444 0,31660355 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30510756 0,320843 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,30510756 0,32070283 ! tRNA processing GO:0008033 89 61 0,000 0,30510756 0,32056279 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30510756 0,32042287 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30924602 0,32462737 ! gonad development GO:0008406 98 62 0,000 0,30924602 0,3244858 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,31335998 0,32865916 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,31335998 0,32851595 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,31335998 0,32837287 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31744957 0,33251357 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31744957 0,33236887 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31744957 0,3322243 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31744957 0,33207986 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31744957 0,33193554 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32151494 0,33604038 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,32151494 0,33589446 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,32151494 0,33574867 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,32151494 0,33560301 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,32151494 0,33545748 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32555623 0,33952678 ! extracellular matrix organization GO:0030198 133 66 0,000 0,32555623 0,33937967 ! secondary metabolic process GO:0019748 116 66 0,000 0,32555623 0,33923269 ! developmental maturation GO:0021700 116 66 0,000 0,32555623 0,33908584 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,32957358 0,34312161 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,32957358 0,3429732 ! hexose catabolic process GO:0019320 104 67 0,000 0,32957358 0,34282492 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,32957358 0,34267677 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,32957358 0,34252874 ! adaptive immune response GO:0002250 119 67 0,000 0,32957358 0,34238085 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,32957358 0,34223308 ! amino acid transport GO:0006865 125 68 0,000 0,33356714 0,3462306 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33356714 0,3460813 ! regulation of lipase activity GO:0060191 130 68 0,000 0,33356714 0,34593213 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,33356714 0,34578308 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33753704 0,34974768 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33753704 0,34959712 ! antigen processing and presentation GO:0019882 104 69 0,000 0,33753704 0,34944669 ! appendage morphogenesis GO:0035107 135 70 0,000 0,34148342 0,35338026 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,34540642 0,35728626 ! appendage development GO:0048736 136 71 0,000 0,34540642 0,35713272 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,34540642 0,35697932 ! B cell activation GO:0042113 160 71 0,000 0,34540642 0,35682604 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,34540642 0,3566729 ! regulation of immune effector process GO:0002697 137 71 0,000 0,34540642 0,35651988 ! acute inflammatory response GO:0002526 113 72 0,000 0,34930618 0,36039051 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,34930618 0,36023604 ! carbohydrate transport GO:0008643 110 72 0,000 0,34930618 0,36008169 ! regulation of blood pressure GO:0008217 125 73 0,000 0,35318284 0,36392202 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,35318284 0,36376623 ! fertilization GO:0009566 90 73 0,000 0,35318284 0,36361057 ! transition metal ion transport GO:0000041 126 74 0,000 0,35703653 0,36742083 ! neurotransmitter transport GO:0006836 123 74 0,000 0,35703653 0,36726374 ! exocytosis GO:0006887 133 74 0,000 0,35703653 0,36710679 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,35703653 0,36694997 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,35703653 0,36679329 ! organelle localization GO:0051640 136 74 0,000 0,35703653 0,36663674 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36086739 0,37041251 ! rhythmic process GO:0048511 128 75 0,000 0,36086739 0,37025456 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,36086739 0,37009673 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,36467555 0,37384293 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,36467555 0,37368372 ! defense response to bacterium GO:0042742 89 76 0,000 0,36467555 0,37352464 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,36467555 0,37336569 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36846114 0,37708103 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,36846114 0,37692071 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,37222431 0,38060845 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,37596517 0,38427027 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37596517 0,38410709 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,37596517 0,38394406 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,37596517 0,38378116 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,37596517 0,38361841 ! muscle cell differentiation GO:0042692 159 80 0,000 0,37968387 0,38724858 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,37968387 0,38708449 ! protein import into nucleus GO:0006606 158 80 0,000 0,37968387 0,38692054 ! T cell activation GO:0042110 168 81 0,000 0,38338053 0,39052225 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,38338053 0,39035699 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,38338053 0,39019186 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,38338053 0,39002687 ! nuclear import GO:0051170 161 81 0,000 0,38338053 0,38986203 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,38705528 0,39343262 ! response to drug GO:0042493 143 82 0,000 0,38705528 0,39326647 ! response to nutrient GO:0007584 125 82 0,000 0,38705528 0,39310047 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,39433958 0,40032955 ! response to unfolded protein GO:0006986 131 85 0,000 0,39794939 0,4038238 ! nucleosome assembly GO:0006334 122 85 0,000 0,39794939 0,40365355 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,39794939 0,40348345 ! amine biosynthetic process GO:0009309 138 86 0,000 0,40153779 0,40695027 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,40153779 0,40677892 ! chromatin assembly GO:0031497 124 86 0,000 0,40153779 0,40660772 ! alcohol catabolic process GO:0046164 130 86 0,000 0,40153779 0,40643666 ! amine transport GO:0015837 155 86 0,000 0,40153779 0,40626574 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,40510493 0,40970259 ! protein localization in nucleus GO:0034504 176 87 0,000 0,40510493 0,40953045 ! cellular respiration GO:0045333 135 88 0,000 0,40865093 0,41294168 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,40865093 0,41276832 ! regulation of neurological system process GO:0031644 148 88 0,000 0,40865093 0,4125951 ! cellular defense response GO:0006968 114 89 0,000 0,4121759 0,41597954 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,4121759 0,41580512 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41567998 0,41916431 ! sterol metabolic process GO:0016125 152 91 0,000 0,41916329 0,42249974 ! response to protein stimulus GO:0051789 149 91 0,000 0,41916329 0,42232281 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41916329 0,42214603 ! regulation of defense response GO:0031347 149 92 0,000 0,42262595 0,42545524 ! nucleosome organization GO:0034728 138 92 0,000 0,42262595 0,4252773 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,42262595 0,42509951 ! vitamin metabolic process GO:0006766 139 92 0,000 0,42262595 0,42492187 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,42606808 0,42820376 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,42606808 0,42802497 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,4294898 0,43128233 ! female pregnancy GO:0007565 164 94 0,000 0,4294898 0,4311024 ! forebrain development GO:0030900 188 95 0,000 0,43289124 0,43433541 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,43289124 0,43415436 ! leukocyte differentiation GO:0002521 202 96 0,000 0,43627251 0,43736319 ! mRNA transport GO:0051028 169 96 0,000 0,43627251 0,43718103 ! positive regulation of immune response GO:0050778 156 96 0,000 0,43627251 0,43699902 ! protein ubiquitination GO:0016567 217 97 0,000 0,43963373 0,44018258 ! response to virus GO:0009615 160 98 0,000 0,44297502 0,44334355 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,44297502 0,44315921 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,4462965 0,4462965