pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6878-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! sex determination GO:0007530 48 24 4,000 1,62E-07 3,959E-04 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 3,000 1,369E-06 1,672E-03 ! negative regulation of ligase activity GO:0051352 116 68 5,000 1,791E-06 1,459E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cell-substrate junction assembly GO:0007044 56 18 3,000 2,283E-06 1,394E-03 ! cell cycle checkpoint GO:0000075 145 71 5,000 2,313E-06 1,13E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 5,000 4,333E-06 1,764E-03 ! C21-steroid hormone metabolic process GO:0008207 38 21 3,000 4,409E-06 1,539E-03 ! regulation of ligase activity GO:0051340 147 84 5,000 6,198E-06 1,893E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 8,255E-06 2,241E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 8,255E-06 2,017E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 2,000 8,255E-06 1,833E-03 GO:0000076|DNA replication checkpoint, ! regulation of cell cycle process GO:0010564 161 90 5,000 9,245E-06 1,882E-03 ! middle ear morphogenesis GO:0042474 14 9 2,000 1,233E-05 2,318E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,384E-05 2,414E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 1,755E-05 2,858E-03 ! regulation of DNA replication initiation GO:0030174 14 10 2,000 1,755E-05 2,68E-03 ! cell junction assembly GO:0034329 85 31 3,000 2,223E-05 3,195E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 4,000 3,056E-05 4,148E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 3,192E-05 4,105E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 3,192E-05 3,899E-03 GO:0042130|negative regulation of T cell proliferation, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 4,000 3,285E-05 3,821E-03 ! actin filament organization GO:0007015 167 72 4,000 4,333E-05 4,812E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 4,000 4,333E-05 4,603E-03 ! cell junction organization GO:0034330 96 37 3,000 4,551E-05 4,632E-03 ! hormone biosynthetic process GO:0042446 62 37 3,000 4,551E-05 4,447E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 2,000 6,524E-05 6,13E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 7,998E-05 7,237E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 9,674E-05 8,441E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 1,389E-04 0,01169804 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 4,000 1,47E-04 0,01197261 GO:0010498|proteasomal protein catabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,603E-04 0,01263114 ! actin filament bundle formation GO:0051017 47 20 2,000 1,603E-04 0,01223641 ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,603E-04 0,01186561 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 1,792E-04 0,01287608 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 1,863E-04 0,01300088 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 1,887E-04 0,01280853 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! apoptotic nuclear changes GO:0030262 34 22 2,000 2,148E-04 0,014184 ! negative regulation of cell motion GO:0051271 142 55 3,000 2,18E-04 0,01401582 ! regulation of DNA replication GO:0006275 105 56 3,000 2,338E-04 0,01464585 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 2,801E-04 0,01710851 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 2,801E-04 0,01669123 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 2,813E-04 0,01635945 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 2,813E-04 0,01597899 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,813E-04 0,01561584 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,813E-04 0,01526882 ! microvillus organization GO:0032528 8 5 1,000 2,813E-04 0,01493689 GO:0030033|microvillus assembly, ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,813E-04 0,01461908 GO:0032414|positive regulation of ion transmembrane transporter activity, ! cellular glucose homeostasis GO:0001678 6 5 1,000 2,813E-04 0,01431452 ! stem cell division GO:0017145 11 5 1,000 2,813E-04 0,01402238 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 2,813E-04 0,01374194 ! DNA catabolic process GO:0006308 94 60 3,000 3,053E-04 0,01462404 ! negative regulation of DNA replication GO:0008156 45 25 2,000 3,171E-04 0,01489628 ! protein tetramerization GO:0051262 57 25 2,000 3,171E-04 0,01461522 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 3,57E-04 0,01615195 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of mitosis GO:0007088 112 63 3,000 3,683E-04 0,0163593 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 160 64 3,000 3,912E-04 0,01706722 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 4,001E-04 0,01714703 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 4,001E-04 0,01685139 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 4,204E-04 0,01740704 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 4,204E-04 0,01711692 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,204E-04 0,01683632 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! early endosome to late endosome transport GO:0045022 16 6 1,000 4,204E-04 0,01656476 ! neural tube patterning GO:0021532 8 6 1,000 4,204E-04 0,01630183 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 4,204E-04 0,01604711 ! negative regulation of B cell activation GO:0050869 14 6 1,000 4,204E-04 0,01580024 ! cellular hormone metabolic process GO:0034754 120 69 3,000 5,214E-04 0,01929834 ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 5,488E-04 0,02001101 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 2,000 5,488E-04 0,01971673 ! prostate gland development GO:0030850 14 7 1,000 5,865E-04 0,02076463 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 5,865E-04 0,020468 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,865E-04 0,02017971 ! male sex determination GO:0030238 15 7 1,000 5,865E-04 0,01989944 ! spindle checkpoint GO:0031577 16 7 1,000 5,865E-04 0,01962685 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 5,865E-04 0,01936162 ! cell differentiation in hindbrain GO:0021533 10 7 1,000 5,865E-04 0,01910346 ! negative regulation of nuclear division GO:0051784 15 7 1,000 5,865E-04 0,0188521 GO:0045839|negative regulation of mitosis, ! negative regulation of nucleotide metabolic process GO:0045980 13 7 1,000 5,865E-04 0,01860727 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 6,052E-04 0,01895602 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 6,052E-04 0,01871607 ! regulation of transcription factor activity GO:0051090 137 75 3,000 7,15E-04 0,0218338 GO:0090046|regulation of transcription regulator activity, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,792E-04 0,02350153 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 7,792E-04 0,02321493 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,792E-04 0,02293523 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,792E-04 0,02266219 ! regulation of respiratory burst GO:0060263 12 8 1,000 7,792E-04 0,02239558 ! formation of primary germ layer GO:0001704 76 34 2,000 7,963E-04 0,02261988 ! cell fate specification GO:0001708 56 34 2,000 7,963E-04 0,02235989 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 8,675E-04 0,02408353 ! steroid biosynthetic process GO:0006694 146 79 3,000 8,693E-04 0,02386175 ! negative regulation of DNA binding GO:0043392 67 36 2,000 9,427E-04 0,02558852 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,983E-04 0,02680118 ! regulation of glycolysis GO:0006110 20 9 1,000 9,983E-04 0,02650987 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 9,983E-04 0,02622481 ! receptor clustering GO:0043113 20 9 1,000 9,983E-04 0,02594583 ! regulation of telomere maintenance GO:0032204 17 9 1,000 9,983E-04 0,02567271 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,022E-03 0,02600376 ! DNA integrity checkpoint GO:0031570 82 38 2,000 1,105E-03 0,02783225 ! regulation of protein stability GO:0031647 77 38 2,000 1,105E-03 0,02754825 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,105E-03 0,02726998 ! negative regulation of binding GO:0051100 71 39 2,000 1,192E-03 0,02913264 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 1,192E-03 0,0288442 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,192E-03 0,02856141 GO:0042593|glucose homeostasis, ! regulation of developmental growth GO:0048638 16 10 1,000 1,244E-03 0,02949433 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,244E-03 0,02921073 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,244E-03 0,02893253 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,244E-03 0,02865958 ! motor axon guidance GO:0008045 22 10 1,000 1,244E-03 0,02839174 ! protein heterooligomerization GO:0051291 17 10 1,000 1,244E-03 0,02812885 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,244E-03 0,02787079 GO:0043470|regulation of carbohydrate catabolic process, ! nucleus organization GO:0006997 73 40 2,000 1,284E-03 0,0285196 ! regulation of DNA binding GO:0051101 167 89 3,000 1,355E-03 0,02982929 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 1,38E-03 0,03010349 ! ear morphogenesis GO:0042471 64 42 2,000 1,48E-03 0,03200664 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,48E-03 0,03172588 ! neuron fate specification GO:0048665 18 11 1,000 1,515E-03 0,03217356 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,515E-03 0,0318962 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,515E-03 0,03162358 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,515E-03 0,03135559 ! adult heart development GO:0007512 16 11 1,000 1,515E-03 0,03109209 ! positive regulation of neuron differentiation GO:0045666 22 11 1,000 1,515E-03 0,03083299 ! regulation of embryonic development GO:0045995 35 11 1,000 1,515E-03 0,03057817 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,585E-03 0,03174436 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 1,809E-03 0,03592141 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,809E-03 0,03563172 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,811E-03 0,03539483 ! virus-host interaction GO:0019048 30 12 1,000 1,811E-03 0,03511392 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,811E-03 0,03483743 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,811E-03 0,03456526 ! focal adhesion formation GO:0048041 37 12 1,000 1,811E-03 0,03429732 ! histone acetylation GO:0016573 27 12 1,000 1,811E-03 0,03403349 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,811E-03 0,03377369 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,927E-03 0,03566765 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,927E-03 0,03539948 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 1,932E-03 0,03522068 ! response to insulin stimulus GO:0032868 98 47 2,000 2,051E-03 0,03710744 ! hormone metabolic process GO:0042445 171 100 3,000 2,08E-03 0,0373607 ! endocrine pancreas development GO:0031018 25 13 1,000 2,133E-03 0,03803227 ! plasma membrane organization GO:0007009 27 13 1,000 2,133E-03 0,03775668 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,133E-03 0,03748504 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! protein homotetramerization GO:0051289 24 13 1,000 2,133E-03 0,03721729 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,133E-03 0,03695334 ! cellular component disassembly GO:0022411 89 48 2,000 2,179E-03 0,0374832 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 2,312E-03 0,03949383 ! activation of caspase activity GO:0006919 95 50 2,000 2,45E-03 0,04156017 ! regulation of S phase GO:0033261 26 14 1,000 2,48E-03 0,04177578 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 2,48E-03 0,04148965 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 2,48E-03 0,0412074 ! negative regulation of immune system process GO:0002683 101 51 2,000 2,593E-03 0,04279666 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 2,741E-03 0,04493615 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,851E-03 0,04643259 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 2,851E-03 0,04612509 ! actin filament polymerization GO:0030041 27 15 1,000 2,851E-03 0,04582163 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,247E-03 0,05184286 ! heterophilic cell adhesion GO:0007157 43 16 1,000 3,247E-03 0,05150621 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 3,247E-03 0,05117392 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! response to osmotic stress GO:0006970 27 16 1,000 3,247E-03 0,05084588 ! intermediate filament-based process GO:0045103 36 16 1,000 3,247E-03 0,05052202 ! axon cargo transport GO:0008088 46 16 1,000 3,247E-03 0,05020226 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,247E-03 0,04988652 ! mRNA splice site selection GO:0006376 44 16 1,000 3,247E-03 0,04957473 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,558E-03 0,05399596 GO:0010952|positive regulation of peptidase activity, ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,667E-03 0,05529654 ! signal complex assembly GO:0007172 47 17 1,000 3,667E-03 0,05495729 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 3,667E-03 0,05462219 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,667E-03 0,05429115 ! gastrulation GO:0007369 122 58 2,000 3,738E-03 0,0550111 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 4,111E-03 0,06013462 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 4,111E-03 0,05977668 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,111E-03 0,05942297 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 4,578E-03 0,065792 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,578E-03 0,06540725 ! memory GO:0007613 34 19 1,000 4,578E-03 0,06502697 ! neuromuscular junction development GO:0007528 43 19 1,000 4,578E-03 0,0646511 ! skeletal system morphogenesis GO:0048705 118 63 2,000 4,718E-03 0,06623942 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 4,931E-03 0,06883137 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 4,931E-03 0,06844028 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 5,069E-03 0,06996537 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,069E-03 0,0695723 ! protein amino acid acetylation GO:0006473 41 20 1,000 5,069E-03 0,06918363 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,069E-03 0,06879928 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,069E-03 0,06841917 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 5,069E-03 0,06804324 ! pancreas development GO:0031016 40 20 1,000 5,069E-03 0,06767142 ! negative regulation of translation GO:0017148 32 20 1,000 5,069E-03 0,06730364 ! positive regulation of cell motion GO:0051272 157 65 2,000 5,149E-03 0,06799601 ! ear development GO:0043583 114 66 2,000 5,373E-03 0,07057567 ! lipid phosphorylation GO:0046834 43 21 1,000 5,583E-03 0,0729387 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 5,583E-03 0,07255073 ! collagen catabolic process GO:0030574 29 21 1,000 5,583E-03 0,07216686 ! negative regulation of cell growth GO:0030308 142 67 2,000 5,603E-03 0,07204753 ! negative regulation of cell size GO:0045792 144 69 2,000 6,081E-03 0,07777879 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 6,081E-03 0,07737369 ! lung development GO:0030324 165 69 2,000 6,081E-03 0,07697279 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 6,081E-03 0,07657602 ! urogenital system development GO:0001655 149 69 2,000 6,081E-03 0,07618332 ! microtubule-based transport GO:0010970 59 22 1,000 6,12E-03 0,07628066 ! cellular response to starvation GO:0009267 37 22 1,000 6,12E-03 0,07589345 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 6,12E-03 0,07551015 ! ureteric bud development GO:0001657 50 22 1,000 6,12E-03 0,0751307 ! G1 phase GO:0051318 44 22 1,000 6,12E-03 0,07475505 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,12E-03 0,07438314 ! positive regulation of B cell activation GO:0050871 42 22 1,000 6,12E-03 0,0740149 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,12E-03 0,0736503 ! protein stabilization GO:0050821 41 22 1,000 6,12E-03 0,07328927 ! negative regulation of kinase activity GO:0033673 145 70 2,000 6,329E-03 0,07541802 ! positive regulation of DNA replication GO:0045740 44 23 1,000 6,679E-03 0,07921196 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 6,679E-03 0,07882929 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 6,679E-03 0,0784503 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 6,679E-03 0,07807494 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 6,679E-03 0,07770316 ! respiratory tube development GO:0030323 171 72 2,000 6,842E-03 0,07921422 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 6,842E-03 0,07884057 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,261E-03 0,0832811 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 7,261E-03 0,08289193 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 7,261E-03 0,08250639 ! negative regulation of catabolic process GO:0009895 52 24 1,000 7,261E-03 0,08212442 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 7,261E-03 0,08174596 ! regulation of caspase activity GO:0043281 136 74 2,000 7,379E-03 0,08268998 ! negative regulation of transferase activity GO:0051348 155 74 2,000 7,379E-03 0,0823124 ! respiratory system development GO:0060541 175 74 2,000 7,379E-03 0,08193825 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 7,656E-03 0,08463682 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 7,865E-03 0,08654967 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 7,865E-03 0,08616156 ! regulation of transmembrane transport GO:0034762 39 25 1,000 7,865E-03 0,08577691 ! leukocyte adhesion GO:0007159 55 25 1,000 7,865E-03 0,08539568 ! receptor metabolic process GO:0043112 53 25 1,000 7,865E-03 0,08501782 ! interaction with host GO:0051701 66 25 1,000 7,865E-03 0,08464329 ! cell-matrix adhesion GO:0007160 181 76 2,000 7,94E-03 0,08507881 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 8,23E-03 0,08779992 ! positive regulation of ligase activity GO:0051351 130 77 2,000 8,23E-03 0,08741818 ! regulation of catabolic process GO:0009894 173 77 2,000 8,23E-03 0,08703975 ! myelination GO:0042552 50 26 1,000 8,491E-03 0,08940738 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 8,491E-03 0,08902366 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 8,491E-03 0,08864322 ! blood coagulation GO:0007596 151 79 2,000 8,828E-03 0,09177801 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 2,000 8,828E-03 0,09138912 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 9,138E-03 0,09419293 ! multicellular organismal catabolic process GO:0044243 38 27 1,000 9,138E-03 0,09379716 ! response to starvation GO:0042594 47 27 1,000 9,138E-03 0,0934047 ! regulation of chromosome organization GO:0033044 49 27 1,000 9,138E-03 0,09301551 ! cellular response to nutrient levels GO:0031669 45 27 1,000 9,138E-03 0,09262956 ! response to hypoxia GO:0001666 178 81 2,000 9,452E-03 0,09541412 ! regulation of peptidase activity GO:0052547 150 82 2,000 9,773E-03 0,09824832 ! cell-substrate adhesion GO:0031589 189 82 2,000 9,773E-03 0,09784566 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 9,806E-03 0,09778391 ! neuron fate commitment GO:0048663 52 28 1,000 9,806E-03 0,09738642 ! protein amino acid acylation GO:0043543 59 28 1,000 9,806E-03 0,09699214 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 9,806E-03 0,09660104 ! glutathione metabolic process GO:0006749 42 28 1,000 9,806E-03 0,09621308 ! response to oxygen levels GO:0070482 183 83 2,000 0,01009981 0,09869532 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01049608 0,10215905 ! somitogenesis GO:0001756 52 29 1,000 0,01049608 0,10175365 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01049608 0,10135147 ! hemostasis GO:0007599 165 85 2,000 0,01077328 0,10361858 ! negative regulation of growth GO:0045926 168 85 2,000 0,01077328 0,10321223 ! regulation of neuron differentiation GO:0045664 187 85 2,000 0,01077328 0,10280906 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 0,01077328 0,10240902 ! mitochondrion organization GO:0007005 159 87 2,000 0,01147217 0,10862987 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01193773 0,11260181 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01193773 0,11216872 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01193773 0,11173896 GO:0008366|axon ensheathment, ! tube morphogenesis GO:0035239 194 89 2,000 0,01219663 0,1137266 ! collagen metabolic process GO:0032963 49 32 1,000 0,01268923 0,1178699 ! spindle organization GO:0007051 50 32 1,000 0,01268923 0,11742342 ! metanephros development GO:0001656 81 32 1,000 0,01268923 0,11698031 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01268923 0,11654054 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01268923 0,11610406 ! mesoderm formation GO:0001707 73 32 1,000 0,01268923 0,11567083 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01268923 0,11524083 ! hindbrain development GO:0030902 65 32 1,000 0,01268923 0,11481401 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01268923 0,11439034 ! gland development GO:0048732 220 91 2,000 0,01294681 0,11628329 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01333158 0,11930057 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01346086 0,12001784 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01372283 0,12190864 ! inner ear morphogenesis GO:0042472 51 34 1,000 0,0142524 0,1261544 ! spliceosome assembly GO:0000245 75 34 1,000 0,0142524 0,12569896 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,0142524 0,12524681 ! ATP biosynthetic process GO:0006754 197 95 2,000 0,01452481 0,12718321 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01493557 0,13031283 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,0150636 0,13096223 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 0,0150636 0,13049783 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,0150636 0,1300367 ! transcription initiation GO:0006352 171 97 2,000 0,01535285 0,13206695 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 0,01577667 0,13523652 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01589425 0,135768 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01589425 0,13529494 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01664396 0,14118472 GO:0060538|skeletal muscle organ development, ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,0167441 0,14154268 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,0167441 0,1410546 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,0167441 0,14056988 ! sister chromatid segregation GO:0000819 65 37 1,000 0,0167441 0,14008847 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,0167441 0,13961036 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,0167441 0,13913549 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,0167441 0,13866385 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01761293 0,1453662 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01761293 0,14487675 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01850052 0,15166705 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,01940665 0,15856336 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01940665 0,15803482 ! maintenance of protein location GO:0045185 95 41 1,000 0,02033109 0,16501279 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,02127362 0,17209091 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,02127362 0,17152295 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02223403 0,17867674 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02223403 0,17809091 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,02223403 0,17750892 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,02223403 0,17693071 ! segmentation GO:0035282 78 43 1,000 0,02223403 0,17635626 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02420761 0,19138895 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02420761 0,19077156 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,02522035 0,19811358 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02522035 0,1974786 ! pigmentation GO:0043473 103 46 1,000 0,02522035 0,19684768 ! cell growth GO:0016049 90 46 1,000 0,02522035 0,19622078 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,02522035 0,19559785 ! neural tube development GO:0021915 91 47 1,000 0,02625012 0,20294003 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02644469 0,2037993 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02644469 0,20315842 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02644469 0,20252156 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02644469 0,20188868 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02644469 0,20125974 ! neuron fate determination GO:0048664 7 5 0,000 0,02644469 0,20063471 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02644469 0,20001355 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02644469 0,19939622 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02644469 0,1987827 ! polyol transport GO:0015791 12 5 0,000 0,02644469 0,19817293 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02644469 0,1975669 ! response to superoxide GO:0000303 10 5 0,000 0,02644469 0,19696456 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02644469 0,19636589 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02644469 0,19577084 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02644469 0,19517939 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02644469 0,1945915 ! female meiosis GO:0007143 10 5 0,000 0,02644469 0,19400714 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02644469 0,19342628 ! hypothalamus development GO:0021854 9 5 0,000 0,02644469 0,19284889 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02644469 0,19227493 ! cobalt ion transport GO:0006824 11 5 0,000 0,02644469 0,19170438 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02644469 0,19113721 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02644469 0,19057338 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02644469 0,19001287 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02644469 0,18945565 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02644469 0,18890169 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02644469 0,18835095 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02644469 0,18780342 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02644469 0,18725906 ! transposition GO:0032196 9 5 0,000 0,02644469 0,18671785 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02644469 0,18617976 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02644469 0,18564476 ! negative chemotaxis GO:0050919 16 5 0,000 0,02644469 0,18511283 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02644469 0,18458393 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02644469 0,18405805 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02644469 0,18353516 ! behavioral response to pain GO:0048266 10 5 0,000 0,02644469 0,18301523 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02644469 0,18249824 ! Notch receptor processing GO:0007220 11 5 0,000 0,02644469 0,18198416 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02644469 0,18147297 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02644469 0,18096464 ! micturition GO:0060073 9 5 0,000 0,02644469 0,18045915 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02644469 0,17995648 ! copulation GO:0007620 9 5 0,000 0,02644469 0,1794566 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02644469 0,17895949 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02644469 0,17846513 ! bioluminescence GO:0008218 9 5 0,000 0,02644469 0,17797349 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02644469 0,17748455 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02644469 0,17699829 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02644469 0,17651469 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02644469 0,17603372 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02644469 0,17555537 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02644469 0,17507961 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02644469 0,17460642 ! grooming behavior GO:0007625 6 5 0,000 0,02644469 0,17413579 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02644469 0,17366768 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02644469 0,17320208 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02644469 0,17273897 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02644469 0,17227834 ! response to protozoan GO:0001562 13 5 0,000 0,02644469 0,17182015 ! lymph vessel development GO:0001945 10 5 0,000 0,02644469 0,17136439 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02644469 0,17091105 ! endochondral ossification GO:0001958 17 5 0,000 0,02644469 0,1704601 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02644469 0,17001152 ! single strand break repair GO:0000012 8 5 0,000 0,02644469 0,16956529 ! parathyroid gland development GO:0060017 14 5 0,000 0,02644469 0,1691214 ! anagen GO:0042640 7 5 0,000 0,02644469 0,16867983 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02644469 0,16824056 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02644469 0,16780358 ! cytokine secretion GO:0050663 15 5 0,000 0,02644469 0,16736885 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02644469 0,16693637 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02644469 0,16650613 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02644469 0,16607809 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02644469 0,16565225 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02644469 0,16522858 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02644469 0,16480708 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02644469 0,16438773 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02644469 0,1639705 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02644469 0,16355538 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02644469 0,16314237 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02644469 0,16273143 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02644469 0,16232255 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02644469 0,16191573 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02644469 0,16151094 ! valine metabolic process GO:0006573 12 5 0,000 0,02644469 0,16110817 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02644469 0,1607074 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02644469 0,16030863 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02644469 0,15991182 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02644469 0,15951698 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02644469 0,15912408 ! polyol catabolic process GO:0046174 9 5 0,000 0,02644469 0,15873311 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02644469 0,15834406 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02644469 0,15795691 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02644469 0,15757165 ! muscle cell migration GO:0014812 8 5 0,000 0,02644469 0,15718826 ! mitochondrial fission GO:0000266 8 5 0,000 0,02644469 0,15680674 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02644469 0,15642706 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02644469 0,15604922 ! mRNA transcription GO:0009299 10 5 0,000 0,02644469 0,1556732 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02644469 0,15529898 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02644469 0,15492656 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02644469 0,15455592 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02644469 0,15418706 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02644469 0,15381994 ! monocyte activation GO:0042117 10 5 0,000 0,02644469 0,15345458 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02644469 0,15309094 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02644469 0,15272902 ! response to food GO:0032094 6 5 0,000 0,02644469 0,15236881 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02644469 0,1520103 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02644469 0,15165347 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02644469 0,15129831 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02644469 0,15094481 ! forebrain neuron development GO:0021884 13 5 0,000 0,02644469 0,15059295 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02644469 0,15024274 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02644469 0,14989415 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02644469 0,14954717 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02644469 0,14920179 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02644469 0,14885801 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02644469 0,14851581 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02644469 0,14817518 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02644469 0,1478361 ! lipid glycosylation GO:0030259 7 5 0,000 0,02644469 0,14749858 ! nucleobase transport GO:0015851 6 5 0,000 0,02644469 0,14716259 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02644469 0,14682813 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02644469 0,14649519 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02644469 0,14616375 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02644469 0,14583381 ! basic amino acid transport GO:0015802 12 5 0,000 0,02644469 0,14550535 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02644469 0,14517837 ! actin nucleation GO:0045010 11 5 0,000 0,02644469 0,14485286 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02644469 0,14452881 ! depurination GO:0045007 5 5 0,000 0,02644469 0,1442062 ! depyrimidination GO:0045008 10 5 0,000 0,02644469 0,14388503 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02644469 0,14356528 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02644469 0,14324695 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02644469 0,14293004 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02644469 0,14261452 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02644469 0,14230039 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02644469 0,14198764 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02644469 0,14167626 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02644469 0,14136625 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02644469 0,14105759 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02644469 0,14075028 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02644469 0,1404443 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02644469 0,14013965 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02644469 0,13983631 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02644469 0,13953429 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02644469 0,13923357 ! response to arsenic GO:0046685 11 5 0,000 0,02644469 0,13893414 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02644469 0,138636 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02644469 0,13833914 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02644469 0,13804354 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02644469 0,1377492 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02644469 0,13745612 ! response to mercury ion GO:0046689 8 5 0,000 0,02644469 0,13716428 ! response to cadmium ion GO:0046686 7 5 0,000 0,02644469 0,13687368 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02644469 0,13658431 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02644469 0,13629615 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02644469 0,13600921 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02644469 0,13572348 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02644469 0,13543894 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02644469 0,1351556 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02644469 0,13487344 ! decidualization GO:0046697 11 5 0,000 0,02644469 0,13459245 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02644469 0,13431263 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02644469 0,13403398 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02644469 0,13375647 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02644469 0,13348012 ! embryonic cleavage GO:0040016 6 5 0,000 0,02644469 0,1332049 ! peroxisome fission GO:0016559 5 5 0,000 0,02644469 0,13293082 ! histone demethylation GO:0016577 13 5 0,000 0,02644469 0,13265786 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02644469 0,13238602 ! mitotic recombination GO:0006312 9 5 0,000 0,02644469 0,13211529 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02644469 0,13184567 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02644469 0,13157714 ! metaphase plate congression GO:0051310 7 5 0,000 0,02644469 0,13130971 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02644469 0,13104336 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02644469 0,13077809 ! enteric nervous system development GO:0048484 8 5 0,000 0,02644469 0,13051389 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02644469 0,13025076 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02644469 0,12998869 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02644469 0,12972766 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02644469 0,12946769 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02644469 0,12920875 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02644469 0,12895085 ! B cell homeostasis GO:0001782 13 5 0,000 0,02644469 0,12869398 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02644469 0,12843812 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02644469 0,12818329 ! metaphase GO:0051323 11 5 0,000 0,02644469 0,12792946 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02644469 0,12767663 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02644469 0,12742481 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02644469 0,12717397 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02644469 0,12692412 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02644469 0,12667525 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02644469 0,12642735 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02644469 0,12618042 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02644469 0,12593446 ! response to redox state GO:0051775 6 5 0,000 0,02644469 0,12568945 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02644469 0,12544539 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02644469 0,12520228 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02644469 0,12496011 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02644469 0,12471887 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02644469 0,12447857 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02644469 0,12423919 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02644469 0,12400072 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02644469 0,12376317 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02644469 0,12352653 ! striatum development GO:0021756 14 5 0,000 0,02644469 0,1232908 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02644469 0,12305596 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02644469 0,12282201 ! glial cell migration GO:0008347 10 5 0,000 0,02644469 0,12258895 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02644469 0,12235677 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02644469 0,12212548 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02644469 0,12189505 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02644469 0,12166549 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02644469 0,1214368 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02644469 0,12120896 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02644469 0,12098198 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02644469 0,12075584 ! neuroprotection GO:0043526 8 5 0,000 0,02644469 0,12053055 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02644469 0,1203061 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02644469 0,12008248 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02644469 0,1198597 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02644469 0,11963773 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02644469 0,11941659 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02644469 0,11919627 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02644469 0,11897675 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02644469 0,11875805 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02644469 0,11854014 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02644469 0,11832303 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02644469 0,11810672 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02644469 0,1178912 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02644469 0,11767646 ! spindle assembly GO:0051225 6 5 0,000 0,02644469 0,1174625 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02644469 0,11724932 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02644469 0,11703691 ! protein palmitoylation GO:0018345 12 5 0,000 0,02644469 0,11682527 ! drug metabolic process GO:0017144 7 5 0,000 0,02644469 0,1166144 ! organ regeneration GO:0031100 7 5 0,000 0,02644469 0,11640428 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02644469 0,11619492 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02644469 0,11598631 ! endosome transport GO:0016197 127 48 1,000 0,02729671 0,11950869 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02729671 0,1192949 ! response to calcium ion GO:0051592 94 49 1,000 0,02835989 0,12372004 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02835989 0,1234995 ! protein homooligomerization GO:0051260 84 49 1,000 0,02835989 0,12327975 ! regulation of action potential GO:0001508 102 50 1,000 0,02943949 0,1277454 ! endocrine system development GO:0035270 109 50 1,000 0,02943949 0,1275189 ! peptide metabolic process GO:0006518 80 51 1,000 0,03053527 0,13203128 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03053527 0,13179801 ! positive regulation of binding GO:0051099 88 52 1,000 0,03164706 0,13635584 ! histone modification GO:0016570 104 52 1,000 0,03164706 0,13611577 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,03164706 0,13587656 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,03164706 0,13563818 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03164955 0,13541129 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03164955 0,13517456 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03164955 0,13493865 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03164955 0,13470357 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03164955 0,1344693 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03164955 0,13423585 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03164955 0,1340032 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03164955 0,13377136 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03164955 0,13354033 ! response to oxygen radical GO:0000305 11 6 0,000 0,03164955 0,13331008 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03164955 0,13308063 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03164955 0,13285197 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03164955 0,1326241 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03164955 0,132397 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03164955 0,13217068 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03164955 0,13194513 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03164955 0,13172036 ! forebrain regionalization GO:0021871 9 6 0,000 0,03164955 0,13149634 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03164955 0,13127309 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03164955 0,13105059 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03164955 0,13082885 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03164955 0,13060785 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03164955 0,1303876 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03164955 0,1301681 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03164955 0,12994933 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03164955 0,12973129 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03164955 0,12951398 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03164955 0,12929741 ! malate metabolic process GO:0006108 13 6 0,000 0,03164955 0,12908155 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03164955 0,12886641 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03164955 0,12865199 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03164955 0,12843829 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03164955 0,12822529 ! protein refolding GO:0042026 15 6 0,000 0,03164955 0,12801299 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03164955 0,1278014 ! opsonization GO:0008228 8 6 0,000 0,03164955 0,12759051 ! mating behavior GO:0007617 7 6 0,000 0,03164955 0,12738031 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03164955 0,1271708 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03164955 0,12696198 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03164955 0,12675385 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03164955 0,1265464 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03164955 0,12633962 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03164955 0,12613352 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03164955 0,12592809 ! toxin metabolic process GO:0009404 11 6 0,000 0,03164955 0,12572333 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03164955 0,12551924 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03164955 0,1253158 ! nuclear migration GO:0007097 13 6 0,000 0,03164955 0,12511302 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03164955 0,1249109 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03164955 0,12470943 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03164955 0,12450861 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03164955 0,12430844 ! thymic T cell selection GO:0045061 16 6 0,000 0,03164955 0,12410891 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03164955 0,12391001 ! protein lipoylation GO:0009249 10 6 0,000 0,03164955 0,12371176 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03164955 0,12351414 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03164955 0,12331714 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03164955 0,12312078 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03164955 0,12292504 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03164955 0,12272992 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03164955 0,12253542 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03164955 0,12234153 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03164955 0,12214826 ! hyperosmotic response GO:0006972 10 6 0,000 0,03164955 0,1219556 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03164955 0,12176354 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03164955 0,12157209 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03164955 0,12138124 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03164955 0,12119099 ! urea metabolic process GO:0019627 7 6 0,000 0,03164955 0,12100133 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03164955 0,12081226 ! neutrophil activation GO:0042119 7 6 0,000 0,03164955 0,12062379 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03164955 0,1204359 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03164955 0,1202486 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03164955 0,12006188 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03164955 0,11987573 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03164955 0,11969017 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03164955 0,11950518 ! neuron apoptosis GO:0051402 15 6 0,000 0,03164955 0,11932075 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03164955 0,1191369 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03164955 0,11895361 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03164955 0,11877089 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03164955 0,11858873 ! carnitine transport GO:0015879 10 6 0,000 0,03164955 0,11840712 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03164955 0,11822607 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03164955 0,11804557 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03164955 0,11786562 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03164955 0,11768622 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03164955 0,11750737 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03164955 0,11732906 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03164955 0,11715129 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03164955 0,11697405 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03164955 0,11679735 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03164955 0,11662119 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03164955 0,11644556 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03164955 0,11627045 ! response to UV-C GO:0010225 14 6 0,000 0,03164955 0,11609587 ! astrocyte development GO:0014002 16 6 0,000 0,03164955 0,11592181 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03164955 0,11574828 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03164955 0,11557526 ! interaction with symbiont GO:0051702 14 6 0,000 0,03164955 0,11540276 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03164955 0,11523077 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03164955 0,1150593 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03164955 0,11488833 ! response to copper ion GO:0046688 10 6 0,000 0,03164955 0,11471788 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03164955 0,11454792 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03164955 0,11437847 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03164955 0,11420953 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03164955 0,11404107 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03164955 0,11387312 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03164955 0,11370566 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03164955 0,11353869 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03164955 0,11337221 ! hair follicle maturation GO:0048820 8 6 0,000 0,03164955 0,11320622 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03164955 0,11304071 ! Schwann cell development GO:0014044 15 6 0,000 0,03164955 0,11287569 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03164955 0,11271115 ! response to pheromone GO:0019236 6 6 0,000 0,03164955 0,11254709 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03164955 0,1123835 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03164955 0,11222039 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03164955 0,11205775 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03164955 0,11189558 ! subpallium development GO:0021544 15 6 0,000 0,03164955 0,11173389 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03164955 0,11157265 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03164955 0,11141189 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03164955 0,11125158 ! G2 phase GO:0051319 16 6 0,000 0,03164955 0,11109174 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03164955 0,11093235 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03164955 0,11077342 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03164955 0,11061495 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03164955 0,11045693 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03164955 0,11029936 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03164955 0,11014223 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03164955 0,10998556 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03164955 0,10982933 ! receptor internalization GO:0031623 11 6 0,000 0,03164955 0,10967354 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03164955 0,1095182 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03164955 0,10936329 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03164955 0,10920883 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03164955 0,10905479 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03164955 0,1089012 ! protein deubiquitination GO:0016579 16 6 0,000 0,03164955 0,10874803 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03164955 0,10859529 ! protein destabilization GO:0031648 9 6 0,000 0,03164955 0,10844299 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03164955 0,1082911 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03164955 0,10813965 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03164955 0,10798862 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03164955 0,107838 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03164955 0,10768781 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03164955 0,10753804 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03164955 0,10738868 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03164955 0,10723973 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03164955 0,1070912 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03164955 0,10694308 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03164955 0,10679537 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03164955 0,10664807 ! neural plate development GO:0001840 9 6 0,000 0,03164955 0,10650117 ! catecholamine transport GO:0051937 9 6 0,000 0,03164955 0,10635468 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03164955 0,10620858 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03164955 0,10606289 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03164955 0,1059176 ! maternal placenta development GO:0001893 12 6 0,000 0,03164955 0,10577271 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03164955 0,10562821 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03164955 0,1054841 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03164955 0,10534039 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03164955 0,10519707 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03164955 0,10505414 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03164955 0,1049116 GO:0055081|anion homeostasis, ! positive regulation of growth GO:0045927 96 53 1,000 0,03277464 0,10849381 ! inner ear development GO:0048839 89 53 1,000 0,03277464 0,108347 ! synapse organization GO:0050808 102 53 1,000 0,03277464 0,10820059 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,03391781 0,1118235 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,03391781 0,11167279 ! covalent chromatin modification GO:0016569 115 54 1,000 0,03391781 0,11152249 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,03391781 0,1113726 ! response to UV GO:0009411 120 55 1,000 0,03507639 0,11502229 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03625016 0,118712 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03625016 0,11855308 ! RNA elongation GO:0006354 90 56 1,000 0,03625016 0,11839459 ! tRNA transcription GO:0009304 17 7 0,000 0,03682673 0,12011709 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03682673 0,11995693 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03682673 0,1197972 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03682673 0,11963789 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03682673 0,11947901 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03682673 0,11932055 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03682673 0,11916251 ! sleep GO:0030431 16 7 0,000 0,03682673 0,11900489 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03682673 0,11884768 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03682673 0,11869089 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03682673 0,11853452 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03682673 0,11837855 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03682673 0,11822299 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03682673 0,11806784 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03682673 0,1179131 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03682673 0,11775877 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03682673 0,11760483 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03682673 0,1174513 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03682673 0,11729817 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03682673 0,11714544 ! glycolipid transport GO:0046836 11 7 0,000 0,03682673 0,1169931 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03682673 0,11684116 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03682673 0,11668962 ! neuron adhesion GO:0007158 14 7 0,000 0,03682673 0,11653847 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03682673 0,11638771 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03682673 0,11623733 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03682673 0,11608735 ! mRNA stabilization GO:0048255 18 7 0,000 0,03682673 0,11593775 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03682673 0,11578854 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03682673 0,11563971 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03682673 0,11549127 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03682673 0,1153432 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03682673 0,11519551 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03682673 0,11504821 ! lipoprotein transport GO:0042953 14 7 0,000 0,03682673 0,11490127 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03682673 0,11475472 ! rhythmic behavior GO:0007622 17 7 0,000 0,03682673 0,11460853 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03682673 0,11446272 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03682673 0,11431728 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03682673 0,1141722 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03682673 0,1140275 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03682673 0,11388316 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03682673 0,11373919 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03682673 0,11359558 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03682673 0,11345233 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03682673 0,11330944 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03682673 0,11316691 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03682673 0,11302475 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03682673 0,11288293 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03682673 0,11274147 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03682673 0,11260037 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03682673 0,11245962 ! spinal cord patterning GO:0021511 14 7 0,000 0,03682673 0,11231922 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03682673 0,11217917 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03682673 0,11203947 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03682673 0,11190012 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03682673 0,11176111 ! adrenal gland development GO:0030325 17 7 0,000 0,03682673 0,11162245 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03682673 0,11148414 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03682673 0,11134616 ! ovulation GO:0030728 10 7 0,000 0,03682673 0,11120853 ! adenohypophysis development GO:0021984 11 7 0,000 0,03682673 0,11107123 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03682673 0,11093428 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03682673 0,11079766 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03682673 0,11066137 ! microtubule nucleation GO:0007020 21 7 0,000 0,03682673 0,11052543 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03682673 0,11038981 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03682673 0,11025453 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03682673 0,11011958 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03682673 0,10998496 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03682673 0,10985067 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03682673 0,1097167 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03682673 0,10958307 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03682673 0,10944975 ! galactose metabolic process GO:0006012 13 7 0,000 0,03682673 0,10931676 ! vesicle fusion GO:0006906 20 7 0,000 0,03682673 0,1091841 ! response to dietary excess GO:0002021 8 7 0,000 0,03682673 0,10905175 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03682673 0,10891973 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03682673 0,10878803 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03682673 0,10865664 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03682673 0,10852557 ! organ growth GO:0035265 15 7 0,000 0,03682673 0,10839482 ! nucleoside transport GO:0015858 11 7 0,000 0,03682673 0,10826438 ! nucleoside salvage GO:0043174 11 7 0,000 0,03682673 0,10813425 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03682673 0,10800444 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03682673 0,10787494 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03682673 0,10774574 ! parturition GO:0007567 16 7 0,000 0,03682673 0,10761686 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03682673 0,10748829 ! rRNA modification GO:0000154 14 7 0,000 0,03682673 0,10736002 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03682673 0,10723206 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03682673 0,1071044 ! monocyte differentiation GO:0030224 16 7 0,000 0,03682673 0,10697705 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03682673 0,10685 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03682673 0,10672325 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03682673 0,1065968 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03682673 0,10647065 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03682673 0,1063448 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03682673 0,10621924 ! fibrinolysis GO:0042730 11 7 0,000 0,03682673 0,10609398 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03682673 0,10596902 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03682673 0,10584435 ! eating behavior GO:0042755 8 7 0,000 0,03682673 0,10571997 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03682673 0,10559589 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03682673 0,10547209 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03682673 0,10534859 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03682673 0,10522538 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03682673 0,10510245 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03682673 0,10497981 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03682673 0,10485746 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03682673 0,10473539 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03682673 0,1046136 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03682673 0,1044921 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03682673 0,10437088 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03682673 0,10424994 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03682673 0,10412928 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03682673 0,1040089 ! histone ubiquitination GO:0016574 9 7 0,000 0,03682673 0,1038888 ! regulation of meiosis GO:0040020 12 7 0,000 0,03682673 0,10376897 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03682673 0,10364942 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03682673 0,10353015 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03682673 0,10341115 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03682673 0,10329242 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03682673 0,10317396 ! transcription termination GO:0006353 14 7 0,000 0,03682673 0,10305578 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03682673 0,10293787 ! anaphase GO:0051322 18 7 0,000 0,03682673 0,10282023 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03682673 0,10270285 ! axonal fasciculation GO:0007413 19 7 0,000 0,03682673 0,10258574 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03682673 0,1024689 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03682673 0,10235233 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03682673 0,10223602 ! diuresis GO:0030146 12 7 0,000 0,03682673 0,10211997 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03682673 0,10200419 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03682673 0,10188867 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03682673 0,10177341 ! antibiotic transport GO:0042891 9 7 0,000 0,03682673 0,10165841 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03682673 0,10154368 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03682673 0,1014292 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03682673 0,10131497 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03682673 0,10120101 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03682673 0,1010873 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03682673 0,10097385 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03682673 0,10086065 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03682673 0,1007477 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03682673 0,10063501 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03682673 0,10052257 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03682673 0,10041038 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03682673 0,10029844 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03682673 0,10018675 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03682673 0,1000753 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03682673 0,09996411 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03682673 0,09985316 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03682673 0,09974246 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03682673 0,099632 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03682673 0,09952179 ! muscle adaptation GO:0043500 13 7 0,000 0,03682673 0,09941182 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03682673 0,09930209 ! retina homeostasis GO:0001895 12 7 0,000 0,03682673 0,09919261 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03682673 0,09908337 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03682673 0,09897436 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03682673 0,0988656 ! chloride transport GO:0006821 102 57 1,000 0,03743895 0,10039886 ! muscle fiber development GO:0048747 131 57 1,000 0,03743895 0,10028877 ! heart morphogenesis GO:0003007 105 57 1,000 0,03743895 0,10017893 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03743895 0,10006932 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,03743895 0,09995996 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,03864256 0,10306089 ! aging GO:0007568 112 58 1,000 0,03864256 0,1029485 ! maintenance of location GO:0051235 124 58 1,000 0,03864256 0,10283635 ! lipid modification GO:0030258 112 60 1,000 0,04109347 0,10923976 ! regulation of endocytosis GO:0030100 104 60 1,000 0,04109347 0,10912102 ! kidney development GO:0001822 133 60 1,000 0,04109347 0,10900254 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04197637 0,11122373 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04197637 0,11110323 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,04197637 0,11098299 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04197637 0,110863 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04197637 0,11074328 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04197637 0,11062382 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04197637 0,11050461 ! male meiosis GO:0007140 9 8 0,000 0,04197637 0,11038566 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04197637 0,11026697 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04197637 0,11014853 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04197637 0,11003034 ! meiotic prophase I GO:0007128 14 8 0,000 0,04197637 0,10991241 ! response to zinc ion GO:0010043 12 8 0,000 0,04197637 0,10979473 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04197637 0,1096773 ! oligopeptide transport GO:0006857 16 8 0,000 0,04197637 0,10956013 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04197637 0,1094432 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04197637 0,10932652 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04197637 0,10921009 ! signal peptide processing GO:0006465 12 8 0,000 0,04197637 0,10909391 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04197637 0,10897798 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04197637 0,10886229 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04197637 0,10874685 ! succinate metabolic process GO:0006105 17 8 0,000 0,04197637 0,10863165 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04197637 0,1085167 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04197637 0,10840199 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04197637 0,10828752 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04197637 0,10817329 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04197637 0,1080593 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04197637 0,10794556 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04197637 0,10783205 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04197637 0,10771878 ! reflex GO:0060004 17 8 0,000 0,04197637 0,10760575 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04197637 0,10749295 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04197637 0,1073804 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04197637 0,10726807 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04197637 0,10715599 ! pigment granule organization GO:0048753 17 8 0,000 0,04197637 0,10704413 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04197637 0,10693251 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04197637 0,10682112 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04197637 0,10670997 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04197637 0,10659904 ! histidine catabolic process GO:0006548 10 8 0,000 0,04197637 0,10648835 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04197637 0,10637788 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04197637 0,10626765 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04197637 0,10615764 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,04197637 0,10604786 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04197637 0,1059383 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04197637 0,10582898 ! melanin metabolic process GO:0006582 17 8 0,000 0,04197637 0,10571988 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04197637 0,105611 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04197637 0,10550234 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04197637 0,10539391 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04197637 0,10528571 ! macrophage activation GO:0042116 13 8 0,000 0,04197637 0,10517772 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04197637 0,10506996 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04197637 0,10496241 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04197637 0,10485509 ! purine salvage GO:0043101 12 8 0,000 0,04197637 0,10474799 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04197637 0,1046411 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04197637 0,10453443 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04197637 0,10442798 ! osteoblast development GO:0002076 17 8 0,000 0,04197637 0,10432175 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04197637 0,10421573 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04197637 0,10410993 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04197637 0,10400434 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04197637 0,10389897 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04197637 0,1037938 ! response to UV-B GO:0010224 17 8 0,000 0,04197637 0,10368886 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04197637 0,10358412 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04197637 0,1034796 ! intermediate filament organization GO:0045109 12 8 0,000 0,04197637 0,10337528 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04197637 0,10327118 ! cellular extravasation GO:0045123 13 8 0,000 0,04197637 0,10316728 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04197637 0,1030636 ! response to antibiotic GO:0046677 11 8 0,000 0,04197637 0,10296012 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04197637 0,10285685 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04197637 0,10275379 ! DNA topological change GO:0006265 12 8 0,000 0,04197637 0,10265093 ! response to tropane GO:0014073 15 8 0,000 0,04197637 0,10254828 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04197637 0,10244583 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04197637 0,10234359 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04197637 0,10224155 ! mast cell activation GO:0045576 14 8 0,000 0,04197637 0,10213972 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04197637 0,10203809 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04197637 0,10193666 ! gas homeostasis GO:0033483 14 8 0,000 0,04197637 0,10183543 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04197637 0,1017344 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04197637 0,10163358 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04197637 0,10153295 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04197637 0,10143252 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04197637 0,10133229 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04197637 0,10123226 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04197637 0,10113242 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04197637 0,10103279 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04197637 0,10093335 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04197637 0,1008341 ! response to tumor cell GO:0002347 16 8 0,000 0,04197637 0,10073505 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04197637 0,10063619 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04197637 0,10053753 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04197637 0,10043906 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04197637 0,10034078 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04197637 0,1002427 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04197637 0,1001448 ! hormone catabolic process GO:0042447 17 8 0,000 0,04197637 0,1000471 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04197637 0,09994959 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04197637 0,09985227 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04197637 0,09975514 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04197637 0,09965819 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04197637 0,09956144 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04197637 0,09946487 ! adult feeding behavior GO:0008343 10 8 0,000 0,04197637 0,09936849 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04197637 0,09927229 ! ATP catabolic process GO:0006200 11 8 0,000 0,04197637 0,09917629 ! blastocyst growth GO:0001832 19 8 0,000 0,04197637 0,09908046 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04197637 0,09898483 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04197637 0,09888937 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04197637 0,0987941 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04197637 0,09869902 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04197637 0,09860411 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04197637 0,09850939 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04197637 0,09841485 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04197637 0,0983205 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04197637 0,09822632 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04197637 0,09813232 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04197637 0,09803851 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04197637 0,09794487 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04197637 0,09785141 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04197637 0,09775813 ! protein prenylation GO:0018342 21 8 0,000 0,04197637 0,09766503 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04197637 0,0975721 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04197637 0,09747935 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04197637 0,09738678 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04197637 0,09729438 ! viral reproductive process GO:0022415 132 62 1,000 0,04360138 0,10096509 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,04360138 0,10086948 ! mesoderm development GO:0007498 128 63 1,000 0,04487625 0,10372061 ! axon extension GO:0048675 16 9 0,000 0,04709863 0,10875421 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04709863 0,10865151 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04709863 0,10854901 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04709863 0,1084467 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04709863 0,10834459 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04709863 0,10824266 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04709863 0,10814093 ! reproductive behavior GO:0019098 22 9 0,000 0,04709863 0,10803939 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04709863 0,10793804 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04709863 0,10783688 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04709863 0,10773591 ! UTP metabolic process GO:0046051 10 9 0,000 0,04709863 0,10763513 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04709863 0,10753453 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,04709863 0,10743413 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04709863 0,10733391 ! artery development GO:0060840 25 9 0,000 0,04709863 0,10723388 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04709863 0,10713403 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04709863 0,10703437 ! equilibrioception GO:0050957 20 9 0,000 0,04709863 0,1069349 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04709863 0,10683561 ! chemosensory behavior GO:0007635 21 9 0,000 0,04709863 0,1067365 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04709863 0,10663758 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04709863 0,10653884 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04709863 0,10644029 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04709863 0,10634191 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04709863 0,10624372 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04709863 0,10614571 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04709863 0,10604788 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04709863 0,10595023 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04709863 0,10585276 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04709863 0,10575547 ! protein targeting to ER GO:0045047 25 9 0,000 0,04709863 0,10565836 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04709863 0,10556142 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04709863 0,10546467 ! T cell selection GO:0045058 27 9 0,000 0,04709863 0,10536809 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04709863 0,10527168 ! glycine catabolic process GO:0006546 15 9 0,000 0,04709863 0,10517546 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04709863 0,10507941 ! endosome organization GO:0007032 20 9 0,000 0,04709863 0,10498353 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04709863 0,10488783 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04709863 0,1047923 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04709863 0,10469695 ! mannose metabolic process GO:0006013 13 9 0,000 0,04709863 0,10460177 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04709863 0,10450677 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04709863 0,10441193 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04709863 0,10431727 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04709863 0,10422278 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04709863 0,10412846 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04709863 0,10403431 ! retinol metabolic process GO:0042572 20 9 0,000 0,04709863 0,10394033 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04709863 0,10384653 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04709863 0,10375289 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04709863 0,10365941 ! macrophage differentiation GO:0030225 15 9 0,000 0,04709863 0,10356611 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04709863 0,10347298 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04709863 0,10338001 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04709863 0,10328721 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04709863 0,10319457 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04709863 0,10310211 ! response to amine stimulus GO:0014075 13 9 0,000 0,04709863 0,1030098 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04709863 0,10291767 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04709863 0,10282569 ! erythrocyte development GO:0048821 17 9 0,000 0,04709863 0,10273388 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04709863 0,10264224 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04709863 0,10255076 ! renal water homeostasis GO:0003091 15 9 0,000 0,04709863 0,10245944 ! postreplication repair GO:0006301 25 9 0,000 0,04709863 0,10236828 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04709863 0,10227729 ! icosanoid secretion GO:0032309 15 9 0,000 0,04709863 0,10218646 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04709863 0,10209579 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04709863 0,10200528 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04709863 0,10191492 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04709863 0,10182473 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04709863 0,1017347 ! sterol catabolic process GO:0016127 14 9 0,000 0,04709863 0,10164483 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04709863 0,10155512 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04709863 0,10146556 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04709863 0,10137617 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04709863 0,10128693 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04709863 0,10119785 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04709863 0,10110892 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04709863 0,10102015 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04709863 0,10093154 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04709863 0,10084308 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04709863 0,10075477 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04709863 0,10066662 ! purine base metabolic process GO:0006144 25 9 0,000 0,04709863 0,10057863 ! pigment granule transport GO:0051904 17 9 0,000 0,04709863 0,10049079 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04709863 0,1004031 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04709863 0,10031556 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04709863 0,10022818 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04709863 0,10014095 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04709863 0,10005387 ! mitochondrion localization GO:0051646 18 9 0,000 0,04709863 0,09996694 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,04878233 0,10345072 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,04878233 0,103361 ! activation of MAPK activity GO:0000187 124 67 1,000 0,05011091 0,10608402 ! chromosome segregation GO:0007059 127 67 1,000 0,05011091 0,10599217 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05145248 0,10873565 ! detection of external stimulus GO:0009581 102 68 1,000 0,05145248 0,10864167 ! viral reproduction GO:0016032 142 68 1,000 0,05145248 0,10854785 ! cell projection assembly GO:0030031 138 68 1,000 0,05145248 0,10845419 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05219364 0,10992161 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05219364 0,10982693 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05219364 0,10973241 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05219364 0,10963806 ! associative learning GO:0008306 21 10 0,000 0,05219364 0,10954387 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05219364 0,10944984 ! phosphate transport GO:0006817 24 10 0,000 0,05219364 0,10935597 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05219364 0,10926227 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05219364 0,10916872 ! CTP metabolic process GO:0046036 11 10 0,000 0,05219364 0,10907533 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05219364 0,10898211 ! GTP metabolic process GO:0046039 11 10 0,000 0,05219364 0,10888904 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05219364 0,10879613 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05219364 0,10870338 ! social behavior GO:0035176 29 10 0,000 0,05219364 0,10861079 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05219364 0,10851835 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05219364 0,10842608 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05219364 0,10833396 ! androgen metabolic process GO:0008209 17 10 0,000 0,05219364 0,10824199 ! phospholipid efflux GO:0033700 19 10 0,000 0,05219364 0,10815018 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05219364 0,10805853 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05219364 0,10796703 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05219364 0,10787569 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05219364 0,1077845 ! lung alveolus development GO:0048286 26 10 0,000 0,05219364 0,10769347 ! pathogenesis GO:0009405 17 10 0,000 0,05219364 0,10760259 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05219364 0,10751186 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05219364 0,10742128 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05219364 0,10733086 ! endoderm development GO:0007492 18 10 0,000 0,05219364 0,10724059 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05219364 0,10715047 ! arginine catabolic process GO:0006527 17 10 0,000 0,05219364 0,10706051 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05219364 0,10697069 ! proline metabolic process GO:0006560 13 10 0,000 0,05219364 0,10688103 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05219364 0,10679151 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05219364 0,10670215 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05219364 0,10661293 ! V(D)J recombination GO:0033151 34 10 0,000 0,05219364 0,10652386 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05219364 0,10643495 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05219364 0,10634618 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05219364 0,10625755 ! B cell proliferation GO:0042100 19 10 0,000 0,05219364 0,10616908 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05219364 0,10608075 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05219364 0,10599257 ! multicellular organism growth GO:0035264 19 10 0,000 0,05219364 0,10590454 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05219364 0,10581665 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05219364 0,10572891 ! ruffle organization GO:0031529 17 10 0,000 0,05219364 0,10564131 ! epithelial cell development GO:0002064 21 10 0,000 0,05219364 0,10555386 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05219364 0,10546656 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05219364 0,10537939 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05219364 0,10529237 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05219364 0,1052055 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05219364 0,10511877 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05219364 0,10503218 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,05219364 0,10494573 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05219364 0,10485943 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05219364 0,10477327 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05219364 0,10468725 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05219364 0,10460137 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05219364 0,10451563 ! segment specification GO:0007379 15 10 0,000 0,05219364 0,10443003 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05219364 0,10434457 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05219364 0,10425925 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05219364 0,10417407 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05219364 0,10408903 ! response to dsRNA GO:0043331 23 10 0,000 0,05219364 0,10400413 ! DNA ligation GO:0006266 18 10 0,000 0,05219364 0,10391937 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05219364 0,10383474 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05219364 0,10375026 ! melanosome localization GO:0032400 16 10 0,000 0,05219364 0,10366591 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05219364 0,10358169 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05219364 0,10349762 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05219364 0,10341368 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05219364 0,10332987 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05219364 0,10324621 ! induction of an organ GO:0001759 17 10 0,000 0,05219364 0,10316267 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05219364 0,10307928 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05219364 0,10299601 ! protein sumoylation GO:0016925 17 10 0,000 0,05219364 0,10291289 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05219364 0,10282989 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05219364 0,10274703 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05219364 0,1026643 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05219364 0,10258171 ! salivary gland development GO:0007431 28 10 0,000 0,05219364 0,10249925 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05219364 0,10241692 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05219364 0,10233472 ! midbrain development GO:0030901 14 10 0,000 0,05219364 0,10225266 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05219364 0,10217073 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05219364 0,10208892 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05219364 0,10200725 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05219364 0,10192571 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05219364 0,1018443 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05219364 0,10176302 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05219364 0,10168187 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05219364 0,10160085 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05219364 0,10151996 ! detection of calcium ion GO:0005513 24 10 0,000 0,05219364 0,10143919 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05219364 0,10135856 ! blastocyst formation GO:0001825 18 10 0,000 0,05219364 0,10127805 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05219364 0,10119767 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05219364 0,10111742 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05219364 0,10103729 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05219364 0,1009573 ! response to nicotine GO:0035094 20 10 0,000 0,05219364 0,10087743 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05219364 0,10079768 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05219364 0,10071806 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,05555333 0,10711665 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,05555333 0,10703217 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05726155 0,11023639 ! respiratory burst GO:0045730 17 11 0,000 0,05726155 0,11014959 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05726155 0,11006292 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05726155 0,1099764 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05726155 0,10989 ! thyroid gland development GO:0030878 26 11 0,000 0,05726155 0,10980375 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,05726155 0,10971763 ! synapsis GO:0007129 14 11 0,000 0,05726155 0,10963164 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05726155 0,10954579 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05726155 0,10946007 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05726155 0,10937449 ! response to pain GO:0048265 27 11 0,000 0,05726155 0,10928904 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05726155 0,10920373 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05726155 0,10911855 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05726155 0,1090335 ! bone resorption GO:0045453 16 11 0,000 0,05726155 0,10894858 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05726155 0,10886379 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05726155 0,10877914 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05726155 0,10869462 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05726155 0,10861023 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05726155 0,10852597 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05726155 0,10844184 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05726155 0,10835784 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05726155 0,10827398 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05726155 0,10819024 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05726155 0,10810663 ! UV protection GO:0009650 20 11 0,000 0,05726155 0,10802315 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05726155 0,1079398 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05726155 0,10785657 ! macroautophagy GO:0016236 19 11 0,000 0,05726155 0,10777348 ! temperature homeostasis GO:0001659 18 11 0,000 0,05726155 0,10769051 ! behavioral fear response GO:0001662 27 11 0,000 0,05726155 0,10760767 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05726155 0,10752496 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05726155 0,10744238 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05726155 0,10735992 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05726155 0,10727759 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05726155 0,10719538 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05726155 0,1071133 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05726155 0,10703135 ! regulation of organ growth GO:0046620 14 11 0,000 0,05726155 0,10694952 ! pigment granule localization GO:0051875 20 11 0,000 0,05726155 0,10686782 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05726155 0,10678624 ! vasoconstriction GO:0042310 20 11 0,000 0,05726155 0,10670479 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05726155 0,10662346 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05726155 0,10654225 ! embryonic axis specification GO:0000578 19 11 0,000 0,05726155 0,10646117 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05726155 0,10638021 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05726155 0,10629937 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05726155 0,10621866 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05726155 0,10613807 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05726155 0,1060576 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05726155 0,10597725 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05726155 0,10589703 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05726155 0,10581693 ! prophase GO:0051324 17 11 0,000 0,05726155 0,10573694 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05726155 0,10565708 ! nucleosome positioning GO:0016584 15 11 0,000 0,05726155 0,10557734 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05726155 0,10549772 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05726155 0,10541822 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05726155 0,10533884 ! apical protein localization GO:0045176 18 11 0,000 0,05726155 0,10525958 ! acid secretion GO:0046717 20 11 0,000 0,05726155 0,10518043 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05726155 0,10510141 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05726155 0,1050225 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05726155 0,10494372 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05726155 0,10486505 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05726155 0,1047865 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05726155 0,10470807 ! cholesterol efflux GO:0033344 21 11 0,000 0,05726155 0,10462975 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05726155 0,10455155 ! oocyte development GO:0048599 20 11 0,000 0,05726155 0,10447347 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05726155 0,1043955 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05726155 0,10431766 ! embryonic gut development GO:0048566 19 11 0,000 0,05726155 0,10423992 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05726155 0,10416231 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05726155 0,1040848 ! activation of innate immune response GO:0002218 16 11 0,000 0,05726155 0,10400742 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05726155 0,10393015 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05726155 0,10385299 ! lysogeny GO:0030069 22 11 0,000 0,05726155 0,10377595 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05726155 0,10369902 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05726155 0,1036222 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05726155 0,1035455 ! nucleus localization GO:0051647 22 11 0,000 0,05726155 0,10346892 ! reproductive structure development GO:0048608 131 75 1,000 0,06119244 0,11049012 ! eye development GO:0001654 155 75 1,000 0,06119244 0,11040852 ! axon guidance GO:0007411 162 75 1,000 0,06119244 0,11032704 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06230251 0,1122456 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06230251 0,11216288 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06230251 0,11208029 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,06230251 0,11199782 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06230251 0,11191547 ! protein complex disassembly GO:0043241 28 12 0,000 0,06230251 0,11183323 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06230251 0,11175113 ! hippocampus development GO:0021766 29 12 0,000 0,06230251 0,11166914 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06230251 0,11158727 ! T cell proliferation GO:0042098 32 12 0,000 0,06230251 0,11150552 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06230251 0,11142389 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06230251 0,11134238 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06230251 0,11126099 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06230251 0,11117972 ! drug transport GO:0015893 16 12 0,000 0,06230251 0,11109856 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06230251 0,11101753 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06230251 0,11093661 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06230251 0,11085581 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06230251 0,11077513 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06230251 0,11069457 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06230251 0,11061412 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06230251 0,11053379 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06230251 0,11045358 ! lipid digestion GO:0044241 21 12 0,000 0,06230251 0,11037348 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06230251 0,1102935 ! entry into host cell GO:0030260 34 12 0,000 0,06230251 0,11021364 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06230251 0,11013389 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06230251 0,11005425 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06230251 0,10997473 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06230251 0,10989533 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06230251 0,10981604 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06230251 0,10973687 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06230251 0,1096578 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06230251 0,10957886 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06230251 0,10950002 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06230251 0,1094213 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06230251 0,1093427 ! cranial nerve development GO:0021545 23 12 0,000 0,06230251 0,1092642 ! fucose catabolic process GO:0019317 25 12 0,000 0,06230251 0,10918582 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06230251 0,10910755 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06230251 0,10902939 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06230251 0,10895135 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06230251 0,10887341 ! zymogen activation GO:0031638 18 12 0,000 0,06230251 0,10879559 ! T cell homeostasis GO:0043029 28 12 0,000 0,06230251 0,10871788 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06230251 0,10864028 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06230251 0,10856279 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06230251 0,10848541 ! oocyte differentiation GO:0009994 21 12 0,000 0,06230251 0,10840814 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06230251 0,10833098 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06230251 0,10825393 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06230251 0,108177 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06230251 0,10810017 ! defense response to fungus GO:0050832 15 12 0,000 0,06230251 0,10802344 ! developmental induction GO:0031128 22 12 0,000 0,06230251 0,10794683 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06230251 0,10787033 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06230251 0,10779393 ! response to cold GO:0009409 17 12 0,000 0,06230251 0,10771765 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06230251 0,10764147 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06230251 0,10756539 ! localization within membrane GO:0051668 26 12 0,000 0,06230251 0,10748943 ! learning or memory GO:0007611 161 76 1,000 0,06263169 0,1079811 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,0640824 0,1104043 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,0640824 0,1103265 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06554441 0,11276407 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06731665 0,11573159 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06731665 0,1156502 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06731665 0,11556893 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06731665 0,11548777 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06731665 0,11540673 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06731665 0,11532579 ! peroxisomal transport GO:0043574 28 13 0,000 0,06731665 0,11524498 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06731665 0,11516427 ! cartilage condensation GO:0001502 22 13 0,000 0,06731665 0,11508368 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06731665 0,11500321 ! organelle fusion GO:0048284 36 13 0,000 0,06731665 0,11492284 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06731665 0,11484259 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06731665 0,11476244 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06731665 0,11468242 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06731665 0,1146025 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06731665 0,11452269 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06731665 0,11444299 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06731665 0,11436341 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06731665 0,11428394 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06731665 0,11420457 ! methionine metabolic process GO:0006555 31 13 0,000 0,06731665 0,11412532 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06731665 0,11404617 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06731665 0,11396714 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06731665 0,11388822 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06731665 0,1138094 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06731665 0,11373069 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06731665 0,1136521 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06731665 0,11357361 ! exocrine system development GO:0035272 34 13 0,000 0,06731665 0,11349523 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06731665 0,11341695 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06731665 0,11333879 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06731665 0,11326073 ! L-glutamate transport GO:0015813 30 13 0,000 0,06731665 0,11318278 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06731665 0,11310494 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06731665 0,11302721 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06731665 0,11294958 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06731665 0,11287205 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06731665 0,11279464 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06731665 0,11271733 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06731665 0,11264013 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06731665 0,11256303 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,06731665 0,11248604 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06731665 0,11240915 ! histone methylation GO:0016571 29 13 0,000 0,06731665 0,11233237 ! chromatin silencing GO:0006342 29 13 0,000 0,06731665 0,11225569 ! gland morphogenesis GO:0022612 31 13 0,000 0,06731665 0,11217912 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06731665 0,11210265 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06731665 0,11202628 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06731665 0,11195002 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06731665 0,11187387 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06731665 0,11179781 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06731665 0,11172186 ! spleen development GO:0048536 24 13 0,000 0,06731665 0,11164602 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06731665 0,11157027 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06731665 0,11149463 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06731665 0,11141909 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06731665 0,11134366 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06731665 0,11126832 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06731665 0,11119309 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06731665 0,11111796 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06731665 0,11104293 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06731665 0,110968 ! insulin secretion GO:0030073 24 13 0,000 0,06731665 0,11089318 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06731665 0,11081845 ! acrosome reaction GO:0007340 19 13 0,000 0,06731665 0,11074383 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06731665 0,1106693 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06731665 0,11059488 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,06850167 0,11246611 ! meiosis GO:0007126 143 81 1,000 0,06999661 0,11484332 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,06999661 0,11476625 ! meiotic cell cycle GO:0051321 144 82 1,000 0,07150221 0,1171562 ! rRNA transcription GO:0009303 28 14 0,000 0,07230412 0,11839073 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07230412 0,11831144 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,07230412 0,11823225 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07230412 0,11815316 ! non-recombinational repair GO:0000726 29 14 0,000 0,07230412 0,11807418 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07230412 0,11799531 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07230412 0,11791654 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07230412 0,11783788 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07230412 0,11775932 ! lipid localization GO:0010876 32 14 0,000 0,07230412 0,11768086 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07230412 0,11760251 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,07230412 0,11752427 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07230412 0,11744613 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07230412 0,11736809 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07230412 0,11729016 ! arginine metabolic process GO:0006525 21 14 0,000 0,07230412 0,11721233 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07230412 0,1171346 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07230412 0,11705697 ! regulation of heart rate GO:0002027 25 14 0,000 0,07230412 0,11697945 ! fear response GO:0042596 34 14 0,000 0,07230412 0,11690204 ! organic alcohol transport GO:0015850 29 14 0,000 0,07230412 0,11682472 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07230412 0,11674751 ! embryo implantation GO:0007566 30 14 0,000 0,07230412 0,11667039 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07230412 0,11659338 ! bone mineralization GO:0030282 18 14 0,000 0,07230412 0,11651647 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07230412 0,11643967 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07230412 0,11636296 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07230412 0,11628636 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07230412 0,11620985 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07230412 0,11613345 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07230412 0,11605715 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07230412 0,11598094 ! ribosome assembly GO:0042255 18 14 0,000 0,07230412 0,11590484 ! cerebellum development GO:0021549 23 14 0,000 0,07230412 0,11582884 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07230412 0,11575293 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07230412 0,11567713 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07230412 0,11560142 ! response to gamma radiation GO:0010332 30 14 0,000 0,07230412 0,11552582 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07230412 0,11545031 ! NADP metabolic process GO:0006739 24 14 0,000 0,07230412 0,1153749 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07230412 0,11529959 ! oxygen transport GO:0015671 22 14 0,000 0,07230412 0,11522438 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07230412 0,11514927 ! male genitalia development GO:0030539 26 14 0,000 0,07230412 0,11507425 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07230412 0,11499933 ! regulation of axon extension GO:0030516 43 14 0,000 0,07230412 0,11492451 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07230412 0,11484979 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07230412 0,11477516 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,07301832 0,1158336 ! inorganic anion transport GO:0015698 156 83 1,000 0,07301832 0,11575843 ! response to metal ion GO:0010038 158 84 1,000 0,07454478 0,11810175 ! negative regulation of transport GO:0051051 164 85 1,000 0,07608144 0,12045817 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,07608144 0,12038016 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07726506 0,12217382 ! lactation GO:0007595 30 15 0,000 0,07726506 0,12209479 ! reproductive cellular process GO:0048610 22 15 0,000 0,07726506 0,12201587 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07726506 0,12193705 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07726506 0,12185833 ! superoxide anion generation GO:0042554 22 15 0,000 0,07726506 0,12177971 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07726506 0,12170119 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07726506 0,12162278 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07726506 0,12154446 ! copper ion transport GO:0006825 22 15 0,000 0,07726506 0,12146625 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07726506 0,12138814 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07726506 0,12131012 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07726506 0,12123221 ! sulfate transport GO:0008272 27 15 0,000 0,07726506 0,1211544 ! response to cAMP GO:0051591 25 15 0,000 0,07726506 0,12107669 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07726506 0,12099907 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07726506 0,12092156 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07726506 0,12084414 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07726506 0,12076683 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07726506 0,12068961 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07726506 0,12061249 ! vesicle coating GO:0006901 38 15 0,000 0,07726506 0,12053547 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07726506 0,12045855 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07726506 0,12038173 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07726506 0,12030501 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07726506 0,12022838 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07726506 0,12015185 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07726506 0,12007542 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07726506 0,11999908 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07726506 0,11992284 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07726506 0,1198467 ! histone deacetylation GO:0016575 24 15 0,000 0,07726506 0,11977066 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07726506 0,11969471 ! water homeostasis GO:0030104 28 15 0,000 0,07726506 0,11961885 ! cofactor transport GO:0051181 30 15 0,000 0,07726506 0,1195431 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07726506 0,11946744 ! muscle maintenance GO:0046716 26 15 0,000 0,07726506 0,11939187 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07726506 0,11931641 ! intestinal absorption GO:0050892 31 15 0,000 0,07726506 0,11924103 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07726506 0,11916575 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07726506 0,11909057 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07726506 0,11901548 ! cell killing GO:0001906 32 15 0,000 0,07726506 0,11894049 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,07726506 0,11886559 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07726506 0,11879078 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07726506 0,11871607 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07726506 0,11864145 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07726506 0,11856693 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07726506 0,1184925 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,07762815 0,11897464 ! regulation of lyase activity GO:0051339 169 86 1,000 0,07762815 0,11890005 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07762815 0,11882555 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,07918476 0,12113236 GO:0070201|regulation of establishment of protein localization, ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08219961 0,12566562 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08219961 0,12558703 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08219961 0,12550854 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08219961 0,12543014 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08219961 0,12535185 ! bone remodeling GO:0046849 28 16 0,000 0,08219961 0,12527365 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08219961 0,12519555 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08219961 0,12511754 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08219961 0,12503964 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08219961 0,12496183 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08219961 0,12488412 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08219961 0,1248065 ! startle response GO:0001964 28 16 0,000 0,08219961 0,12472898 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08219961 0,12465156 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08219961 0,12457423 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08219961 0,124497 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08219961 0,12441986 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08219961 0,12434282 ! pituitary gland development GO:0021983 30 16 0,000 0,08219961 0,12426588 ! lysosomal transport GO:0007041 31 16 0,000 0,08219961 0,12418903 ! fructose metabolic process GO:0006000 25 16 0,000 0,08219961 0,12411227 ! L-amino acid transport GO:0015807 33 16 0,000 0,08219961 0,12403561 ! stem cell development GO:0048864 46 16 0,000 0,08219961 0,12395905 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08219961 0,12388258 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08219961 0,1238062 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08219961 0,12372992 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08219961 0,12365373 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08219961 0,12357764 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08219961 0,12350164 ! DNA replication initiation GO:0006270 28 16 0,000 0,08219961 0,12342573 ! neuron recognition GO:0008038 40 16 0,000 0,08219961 0,12334991 ! tissue regeneration GO:0042246 27 16 0,000 0,08219961 0,12327419 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08219961 0,12319856 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08219961 0,12312303 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08219961 0,12304759 ! biomineral formation GO:0031214 22 16 0,000 0,08219961 0,12297223 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08219961 0,12289698 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08219961 0,12282181 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08219961 0,12274674 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08219961 0,12267175 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08219961 0,12259686 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08219961 0,12252206 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08219961 0,12244735 ! peptide hormone processing GO:0016486 27 16 0,000 0,08219961 0,12237274 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,08232709 0,12248787 ! response to inorganic substance GO:0010035 173 90 1,000 0,08391251 0,12477071 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,08550725 0,12706461 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,08550725 0,12698736 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08710791 0,12928593 ! metencephalon development GO:0022037 32 17 0,000 0,08710791 0,12920743 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08710791 0,12912903 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08710791 0,12905072 ! filopodium assembly GO:0046847 42 17 0,000 0,08710791 0,12897251 ! endothelial cell migration GO:0043542 31 17 0,000 0,08710791 0,12889439 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08710791 0,12881637 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08710791 0,12873844 ! glial cell development GO:0021782 28 17 0,000 0,08710791 0,1286606 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08710791 0,12858286 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08710791 0,12850521 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08710791 0,12842766 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08710791 0,1283502 ! myoblast differentiation GO:0045445 50 17 0,000 0,08710791 0,12827284 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08710791 0,12819556 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,08710791 0,12811838 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08710791 0,1280413 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08710791 0,1279643 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08710791 0,1278874 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08710791 0,12781059 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08710791 0,12773387 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08710791 0,12765725 ! membrane budding GO:0006900 42 17 0,000 0,08710791 0,12758072 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08710791 0,12750428 ! regulation of protein binding GO:0043393 33 17 0,000 0,08710791 0,12742793 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08710791 0,12735167 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08710791 0,1272755 ! genitalia development GO:0048806 32 17 0,000 0,08710791 0,12719942 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08710791 0,12712344 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08710791 0,12704754 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08710791 0,12697174 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,08710791 0,12689603 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08710791 0,1268204 ! steroid catabolic process GO:0006706 34 17 0,000 0,08710791 0,12674487 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08710791 0,12666943 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08710791 0,12659407 ! gas transport GO:0015669 26 17 0,000 0,08710791 0,12651881 ! organic cation transport GO:0015695 32 17 0,000 0,08710791 0,12644363 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08710791 0,12636855 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08710791 0,12629355 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08710791 0,12621865 ! bone development GO:0060348 206 92 1,000 0,08711115 0,12614852 ! regulation of membrane potential GO:0042391 179 94 1,000 0,0903459 0,13075535 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,09197646 0,13303641 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,0919901 0,13297741 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0919901 0,13289877 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0919901 0,13282023 ! limbic system development GO:0021761 40 18 0,000 0,0919901 0,13274177 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0919901 0,13266341 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0919901 0,13258515 ! adult walking behavior GO:0007628 36 18 0,000 0,0919901 0,13250697 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0919901 0,13242889 ! heart looping GO:0001947 34 18 0,000 0,0919901 0,1323509 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0919901 0,132273 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0919901 0,13219519 ! centrosome cycle GO:0007098 26 18 0,000 0,0919901 0,13211747 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,0919901 0,13203985 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0919901 0,13196231 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,0919901 0,13188487 ! glycine metabolic process GO:0006544 30 18 0,000 0,0919901 0,13180752 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0919901 0,13173026 ! response to retinoic acid GO:0032526 31 18 0,000 0,0919901 0,13165309 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0919901 0,13157601 ! DNA integration GO:0015074 32 18 0,000 0,0919901 0,13149902 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0919901 0,13142212 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0919901 0,13134531 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0919901 0,13126859 ! neural crest cell migration GO:0001755 41 18 0,000 0,0919901 0,13119196 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0919901 0,13111541 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0919901 0,13103896 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0919901 0,1309626 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0919901 0,13088633 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0919901 0,13081014 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0919901 0,13073404 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0919901 0,13065804 ! detection of bacterium GO:0016045 22 18 0,000 0,0919901 0,13058212 ! nerve development GO:0021675 34 18 0,000 0,0919901 0,13050628 ! defense response to virus GO:0051607 43 18 0,000 0,0919901 0,13043054 ! microspike assembly GO:0030035 46 18 0,000 0,0919901 0,13035488 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0919901 0,13027932 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,0919901 0,13020384 ! sex differentiation GO:0007548 171 96 1,000 0,09361563 0,1324279 ! regulation of protein localization GO:0032880 188 97 1,000 0,09526327 0,13468065 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09684632 0,13683953 ! positive regulation of translation GO:0045727 31 19 0,000 0,09684632 0,13676044 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09684632 0,13668143 ! neuron maturation GO:0042551 46 19 0,000 0,09684632 0,13660251 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09684632 0,13652369 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09684632 0,13644496 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09684632 0,13636631 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09684632 0,13628776 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09684632 0,1362093 ! inositol metabolic process GO:0006020 33 19 0,000 0,09684632 0,13613093 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09684632 0,13605265 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09684632 0,13597446 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09684632 0,13589635 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09684632 0,13581834 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09684632 0,13574042 ! cerebral cortex development GO:0021987 40 19 0,000 0,09684632 0,13566259 ! pigmentation during development GO:0048066 42 19 0,000 0,09684632 0,13558484 ! response to vitamin A GO:0033189 32 19 0,000 0,09684632 0,13550719 ! heme metabolic process GO:0042168 40 19 0,000 0,09684632 0,13542962 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09684632 0,13535215 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09684632 0,13527476 ! response to fungus GO:0009620 26 19 0,000 0,09684632 0,13519746 ! peptide cross-linking GO:0018149 39 19 0,000 0,09684632 0,13512025 ! protein export from nucleus GO:0006611 40 19 0,000 0,09684632 0,13504312 ! heart process GO:0003015 32 19 0,000 0,09684632 0,13496609 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09684632 0,13488914 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09684632 0,13481228 ! visual learning GO:0008542 38 19 0,000 0,09684632 0,13473551 ! cellular pigmentation GO:0033059 37 19 0,000 0,09684632 0,13465882 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09684632 0,13458223 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09684632 0,13450572 ! vitamin transport GO:0051180 31 19 0,000 0,09684632 0,13442929 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09684632 0,13435295 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09684632 0,1342767 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09684632 0,13420054 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09684632 0,13412446 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09684632 0,13404847 ! cilium assembly GO:0042384 38 19 0,000 0,09684632 0,13397257 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09684632 0,13389675 ! protein secretion GO:0009306 45 20 0,000 0,1016767 0,14049557 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1016767 0,14041615 ! positive regulation of ossification GO:0045778 50 20 0,000 0,1016767 0,14033682 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,1016767 0,14025758 ! skin development GO:0043588 42 20 0,000 0,1016767 0,14017842 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,1016767 0,14009936 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,1016767 0,14002039 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1016767 0,1399415 ! response to vitamin GO:0033273 36 20 0,000 0,1016767 0,13986271 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,1016767 0,139784 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,1016767 0,13970538 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1016767 0,13962685 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1016767 0,13954841 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1016767 0,13947006 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,1016767 0,13939179 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1016767 0,13931361 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,1016767 0,13923552 ! body fluid secretion GO:0007589 33 20 0,000 0,1016767 0,13915752 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,1016767 0,1390796 ! peptide secretion GO:0002790 38 20 0,000 0,1016767 0,13900177 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1016767 0,13892403 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,1016767 0,13884638 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,1016767 0,13876881 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1016767 0,13869133 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1016767 0,13861393 ! cell-cell junction organization GO:0045216 43 20 0,000 0,1016767 0,13853662 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,1016767 0,1384594 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,1016767 0,13838227 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1016767 0,13830522 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,1016767 0,13822825 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,1016767 0,13815137 ! regulation of glucose import GO:0046324 30 20 0,000 0,1016767 0,13807458 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,1016767 0,13799787 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1016767 0,13792125 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,1016767 0,13784471 ! regulation of cell killing GO:0031341 46 21 0,000 0,10648138 0,14427842 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10648138 0,14419845 ! hormone secretion GO:0046879 39 21 0,000 0,10648138 0,14411856 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10648138 0,14403876 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10648138 0,14395905 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10648138 0,14387942 ! ovarian follicle development GO:0001541 39 21 0,000 0,10648138 0,14379989 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10648138 0,14372044 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10648138 0,14364108 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10648138 0,14356181 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10648138 0,14348263 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10648138 0,14340353 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10648138 0,14332452 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10648138 0,14324559 ! sensory perception of pain GO:0019233 33 21 0,000 0,10648138 0,14316676 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10648138 0,14308801 ! diencephalon development GO:0021536 36 21 0,000 0,10648138 0,14300935 ! collagen fibril organization GO:0030199 62 21 0,000 0,10648138 0,14293077 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,10648138 0,14285228 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,10648138 0,14277387 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,10648138 0,14269556 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10648138 0,14261732 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10648138 0,14253918 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10648138 0,14246112 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10648138 0,14238314 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10648138 0,14230525 ! actin filament-based movement GO:0030048 47 21 0,000 0,10648138 0,14222745 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,10648138 0,14214973 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11126049 0,1484486 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11126049 0,14836757 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11126049 0,14828662 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11126049 0,14820577 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11126049 0,148125 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11126049 0,14804432 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,11126049 0,14796373 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11126049 0,14788323 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,11126049 0,14780282 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11126049 0,14772249 ! vacuolar transport GO:0007034 41 22 0,000 0,11126049 0,14764225 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11126049 0,1475621 ! fucose metabolic process GO:0006004 44 22 0,000 0,11126049 0,14748203 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11126049 0,14740205 ! cell aging GO:0007569 48 22 0,000 0,11126049 0,14732216 ! stem cell differentiation GO:0048863 57 22 0,000 0,11126049 0,14724235 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11126049 0,14716263 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,11126049 0,147083 ! cytolysis GO:0019835 27 22 0,000 0,11126049 0,14700345 ! renal system process GO:0003014 42 22 0,000 0,11126049 0,14692399 ! vasodilation GO:0042311 40 22 0,000 0,11126049 0,14684461 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11126049 0,14676532 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,11126049 0,14668612 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11126049 0,146607 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11126049 0,14652797 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11126049 0,14644902 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,11126049 0,14637016 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11126049 0,14629138 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11126049 0,14621268 ! sarcomere organization GO:0045214 32 22 0,000 0,11126049 0,14613408 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11126049 0,14605555 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11126049 0,14597711 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11126049 0,14589875 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11126049 0,14582048 ! gut development GO:0048565 44 22 0,000 0,11126049 0,1457423 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11126049 0,14566419 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11126049 0,14558617 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11601418 0,15172518 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11601418 0,151644 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11601418 0,15156291 ! gluconeogenesis GO:0006094 38 23 0,000 0,11601418 0,1514819 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11601418 0,15140098 ! viral genome replication GO:0019079 44 23 0,000 0,11601418 0,15132015 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11601418 0,1512394 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,11601418 0,15115874 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11601418 0,15107817 ! regeneration GO:0031099 42 23 0,000 0,11601418 0,15099768 ! axis specification GO:0009798 43 23 0,000 0,11601418 0,15091727 ! visual behavior GO:0007632 46 23 0,000 0,11601418 0,15083696 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11601418 0,15075672 ! response to ethanol GO:0045471 47 23 0,000 0,11601418 0,15067658 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11601418 0,15059651 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11601418 0,15051654 ! peroxisome organization GO:0007031 43 23 0,000 0,11601418 0,15043665 ! lysosome organization GO:0007040 47 23 0,000 0,11601418 0,15035684 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11601418 0,15027712 ! vesicle targeting GO:0006903 49 23 0,000 0,11601418 0,15019748 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11601418 0,15011792 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11601418 0,15003845 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11601418 0,14995907 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11601418 0,14987977 ! DNA modification GO:0006304 36 23 0,000 0,11601418 0,14980055 ! fatty acid transport GO:0015908 47 23 0,000 0,11601418 0,14972142 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11601418 0,14964237 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11601418 0,1495634 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11601418 0,14948451 ! hormone transport GO:0009914 41 23 0,000 0,11601418 0,14940571 ! cell-cell recognition GO:0009988 28 23 0,000 0,11601418 0,149327 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11601418 0,14924836 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11601418 0,14916981 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11601418 0,14909134 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12074257 0,15508628 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12074257 0,15500479 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12074257 0,15492338 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12074257 0,15484205 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12074257 0,15476081 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12074257 0,15467966 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,12074257 0,15459859 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,12074257 0,15451761 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,12074257 0,15443671 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,12074257 0,15435589 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,12074257 0,15427516 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,12074257 0,15419452 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,12074257 0,15411395 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12074257 0,15403348 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,12074257 0,15395308 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,12074257 0,15387277 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12074257 0,15379255 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12074257 0,15371241 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12074257 0,15363235 ! membrane depolarization GO:0051899 45 24 0,000 0,12074257 0,15355237 ! pallium development GO:0021543 56 24 0,000 0,12074257 0,15347248 ! oogenesis GO:0048477 44 24 0,000 0,12074257 0,15339267 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,12074257 0,15331295 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12074257 0,1532333 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,12074257 0,15315374 ! platelet activation GO:0030168 41 24 0,000 0,12074257 0,15307426 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12074257 0,15299487 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12074257 0,15291556 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12074257 0,15283633 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12074257 0,15275718 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12074257 0,15267811 ! regulation of amine transport GO:0051952 41 24 0,000 0,12074257 0,15259912 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,12544581 0,15846128 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12544581 0,15837939 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12544581 0,15829758 ! phototransduction GO:0007602 37 25 0,000 0,12544581 0,15821586 ! keratinization GO:0031424 37 25 0,000 0,12544581 0,15813422 ! vasculogenesis GO:0001570 49 25 0,000 0,12544581 0,15805266 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,12544581 0,15797119 ! vacuole organization GO:0007033 49 25 0,000 0,12544581 0,15788981 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12544581 0,1578085 ! chromosome condensation GO:0030261 48 25 0,000 0,12544581 0,15772728 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12544581 0,15764615 ! regulation of behavior GO:0050795 48 25 0,000 0,12544581 0,1575651 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12544581 0,15748413 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12544581 0,15740324 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12544581 0,15732244 ! immunoglobulin production GO:0002377 62 25 0,000 0,12544581 0,15724172 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12544581 0,15716108 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,12544581 0,15708053 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12544581 0,15700006 ! liver development GO:0001889 55 25 0,000 0,12544581 0,15691967 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13012402 0,16268832 ! initiation of viral infection GO:0019059 60 26 0,000 0,13012402 0,1626051 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13012402 0,16252197 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13012402 0,16243892 ! molting cycle process GO:0022404 52 26 0,000 0,13012402 0,16235596 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13012402 0,16227309 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,13012402 0,16219029 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13012402 0,16210759 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,13012402 0,16202496 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13012402 0,16194242 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13012402 0,16185997 ! digestive system process GO:0022600 49 26 0,000 0,13012402 0,1617776 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13012402 0,16169531 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13012402 0,1616131 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13012402 0,16153098 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,13012402 0,16144895 ! neural crest cell development GO:0014032 59 26 0,000 0,13012402 0,16136699 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13012402 0,16128512 ! negative regulation of cell development GO:0010721 83 26 0,000 0,13012402 0,16120333 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13012402 0,16112163 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13012402 0,16104001 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13012402 0,16095847 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13012402 0,16087701 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13012402 0,16079564 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13012402 0,16071435 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,13012402 0,16063314 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,13012402 0,16055201 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13012402 0,16047096 ! blastocyst development GO:0001824 50 26 0,000 0,13012402 0,16039 ! telomere organization GO:0032200 46 26 0,000 0,13012402 0,16030912 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13012402 0,16022831 ! neural tube closure GO:0001843 58 26 0,000 0,13012402 0,16014759 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,13012402 0,16006696 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13012402 0,1599864 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13012402 0,15990592 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13477733 0,16554099 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13477733 0,1654578 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13477733 0,1653747 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13477733 0,16529168 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13477733 0,16520874 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13477733 0,16512589 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13477733 0,16504312 ! iron ion transport GO:0006826 65 27 0,000 0,13477733 0,16496043 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,13477733 0,16487783 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13477733 0,16479531 ! tube lumen formation GO:0035148 59 27 0,000 0,13477733 0,16471287 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13477733 0,16463051 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,13477733 0,16454824 ! response to toxin GO:0009636 49 27 0,000 0,13477733 0,16446605 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,13477733 0,16438394 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13477733 0,16430191 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13477733 0,16421996 GO:0032943|mononuclear cell proliferation, ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,13940589 0,16977496 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13940589 0,16969037 ! vesicle docking GO:0048278 55 28 0,000 0,13940589 0,16960587 ! circadian rhythm GO:0007623 56 28 0,000 0,13940589 0,16952144 ! dendrite development GO:0016358 67 28 0,000 0,13940589 0,1694371 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,13940589 0,16935285 ! fat cell differentiation GO:0045444 57 28 0,000 0,13940589 0,16926868 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13940589 0,16918459 ! sperm motility GO:0030317 37 28 0,000 0,13940589 0,16910058 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13940589 0,16901666 ! base-excision repair GO:0006284 41 28 0,000 0,13940589 0,16893283 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13940589 0,16884907 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13940589 0,1687654 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13940589 0,16868181 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13940589 0,16859831 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13940589 0,16851488 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13940589 0,16843154 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13940589 0,16834828 ! lipid oxidation GO:0034440 48 28 0,000 0,13940589 0,16826511 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13940589 0,16818201 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13940589 0,168099 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,14400981 0,17356485 ! translational initiation GO:0006413 66 29 0,000 0,14400981 0,17347927 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14400981 0,17339377 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14400981 0,17330835 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,14400981 0,17322302 ! autophagy GO:0006914 47 29 0,000 0,14400981 0,17313777 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14400981 0,17305261 ! primary neural tube formation GO:0014020 61 29 0,000 0,14400981 0,17296753 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14400981 0,17288253 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14400981 0,17279762 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,14400981 0,17271279 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,14400981 0,17262805 ! synaptogenesis GO:0007416 46 29 0,000 0,14400981 0,17254338 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14400981 0,1724588 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14400981 0,17237431 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,14400981 0,17228989 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,14858923 0,17768159 ! phenol metabolic process GO:0018958 56 30 0,000 0,14858923 0,17759466 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,14858923 0,17750782 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14858923 0,17742106 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14858923 0,17733438 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,14858923 0,1772478 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,14858923 0,17716129 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14858923 0,17707487 ! acute-phase response GO:0006953 50 30 0,000 0,14858923 0,17698853 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14858923 0,17690228 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14858923 0,17681612 ! myofibril assembly GO:0030239 50 30 0,000 0,14858923 0,17673003 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,14858923 0,17664403 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,14858923 0,17655811 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14858923 0,17647228 ! cell fate determination GO:0001709 64 30 0,000 0,14858923 0,17638653 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,14858923 0,17630087 ! phospholipid transport GO:0015914 65 30 0,000 0,14858923 0,17621528 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14858923 0,17612978 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14858923 0,17604437 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14858923 0,17595903 ! tissue homeostasis GO:0001894 50 30 0,000 0,14858923 0,17587378 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,14858923 0,17578861 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15314428 0,18108977 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15314428 0,18100216 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15314428 0,18091464 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15314428 0,1808272 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15314428 0,18073984 ! ovulation cycle process GO:0022602 55 31 0,000 0,15314428 0,18065257 ! peptide transport GO:0015833 60 31 0,000 0,15314428 0,18056538 ! male gonad development GO:0008584 56 31 0,000 0,15314428 0,18047828 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,15314428 0,18039126 ! detection of light stimulus GO:0009583 44 31 0,000 0,15314428 0,18030432 ! natural killer cell activation GO:0030101 50 31 0,000 0,15314428 0,18021747 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15314428 0,1801307 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15314428 0,18004402 ! eye morphogenesis GO:0048592 65 31 0,000 0,15314428 0,17995742 ! response to heat GO:0009408 54 31 0,000 0,15314428 0,1798709 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15314428 0,17978446 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15767509 0,18501452 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15767509 0,1849257 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,15767509 0,18483697 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15767509 0,18474831 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15767509 0,18465975 ! muscle cell development GO:0055001 52 32 0,000 0,15767509 0,18457127 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15767509 0,18448287 ! ovulation cycle GO:0042698 57 32 0,000 0,15767509 0,18439456 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15767509 0,18430633 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15767509 0,18421819 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15767509 0,18413013 ! gene silencing GO:0016458 71 32 0,000 0,15767509 0,18404216 ! regulation of pH GO:0006885 56 33 0,000 0,16218178 0,18921208 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,16218178 0,18912176 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16218178 0,18903153 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16218178 0,18894139 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,16218178 0,18885133 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16218178 0,18876136 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,16218178 0,18867147 ! response to ionizing radiation GO:0010212 74 33 0,000 0,16218178 0,18858167 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,16218178 0,18849196 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16218178 0,18840233 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,16218178 0,18831278 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16218178 0,18822332 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,16218178 0,18813395 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,16218178 0,18804466 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16666449 0,19315054 ! glial cell differentiation GO:0010001 67 34 0,000 0,16666449 0,19305896 ! post-embryonic development GO:0009791 76 34 0,000 0,16666449 0,19296746 ! cholesterol transport GO:0030301 62 34 0,000 0,16666449 0,19287605 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16666449 0,19278473 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16666449 0,19269349 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16666449 0,19260234 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,16666449 0,19251128 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16666449 0,1924203 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16666449 0,1923294 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,17112334 0,19738164 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,17112334 0,19728849 ! negative regulation of secretion GO:0051048 68 35 0,000 0,17112334 0,19719543 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,17112334 0,19710246 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,17112334 0,19700957 ! membrane docking GO:0022406 69 35 0,000 0,17112334 0,19691678 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,17112334 0,19682407 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,17112334 0,19673144 ! ceramide metabolic process GO:0006672 72 35 0,000 0,17112334 0,19663891 ! telencephalon development GO:0021537 81 35 0,000 0,17112334 0,19654646 ! sterol transport GO:0015918 63 35 0,000 0,17112334 0,1964541 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,17112334 0,19636182 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,17112334 0,19626963 ! placenta development GO:0001890 53 35 0,000 0,17112334 0,19617753 ! vesicle localization GO:0051648 70 35 0,000 0,17112334 0,19608551 ! regulation of muscle development GO:0048634 82 36 0,000 0,17555846 0,20107328 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,17555846 0,20097906 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17555846 0,20088492 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17555846 0,20079087 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17555846 0,20069691 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17555846 0,20060304 ! regulation of proteolysis GO:0030162 77 36 0,000 0,17555846 0,20050926 ! aerobic respiration GO:0009060 56 36 0,000 0,17555846 0,20041556 ! cytokine production GO:0001816 68 36 0,000 0,17555846 0,20032196 ! embryonic organ development GO:0048568 67 36 0,000 0,17555846 0,20022843 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17555846 0,200135 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17555846 0,20004165 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,17996997 0,20497279 ! odontogenesis GO:0042476 74 37 0,000 0,17996997 0,20487727 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17996997 0,20478185 ! tissue remodeling GO:0048771 78 37 0,000 0,17996997 0,20468651 ! female gonad development GO:0008585 71 37 0,000 0,17996997 0,20459126 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,18435799 0,20948213 ! meiosis I GO:0007127 74 38 0,000 0,18435799 0,20938474 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,18435799 0,20928744 ! organic anion transport GO:0015711 82 38 0,000 0,18435799 0,20919024 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18435799 0,20909312 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18435799 0,20899609 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18435799 0,20889915 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18435799 0,20880231 ! spermatid development GO:0007286 69 38 0,000 0,18435799 0,20870555 ! glycogen metabolic process GO:0005977 63 38 0,000 0,18435799 0,20860888 ! pigment metabolic process GO:0042440 87 38 0,000 0,18435799 0,2085123 ! neural tube formation GO:0001841 79 38 0,000 0,18435799 0,20841582 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,18872266 0,21325137 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18872266 0,21315278 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18872266 0,21305428 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18872266 0,21295587 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,18872266 0,21285756 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18872266 0,21275933 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,18872266 0,21266119 ! glucan metabolic process GO:0044042 64 39 0,000 0,18872266 0,21256315 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,1930641 0,21735281 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,1930641 0,21725269 ! learning GO:0007612 82 40 0,000 0,1930641 0,21715267 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,1930641 0,21705274 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,1930641 0,2169529 ! mismatch repair GO:0006298 58 40 0,000 0,1930641 0,21685315 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,1930641 0,21675349 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,1930641 0,21665393 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19738243 0,22139819 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19738243 0,22129659 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19738243 0,22119508 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,19738243 0,22109366 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,19738243 0,22099233 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19738243 0,2208911 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19738243 0,22078996 ! gliogenesis GO:0042063 91 41 0,000 0,19738243 0,22068891 ! feeding behavior GO:0007631 69 41 0,000 0,19738243 0,22058795 ! mesenchymal cell development GO:0014031 94 41 0,000 0,19738243 0,22048709 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,19738243 0,22038632 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19738243 0,22028564 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,19738243 0,22018505 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,19738243 0,22008456 ! RNA modification GO:0009451 64 41 0,000 0,19738243 0,21998415 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,20167776 0,22466884 ! organic ether metabolic process GO:0018904 59 42 0,000 0,20167776 0,22456644 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,20167776 0,22446413 ! T cell differentiation GO:0030217 93 42 0,000 0,20167776 0,22436192 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,20167776 0,2242598 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,20167776 0,22415777 ! regulation of protein secretion GO:0050708 77 42 0,000 0,20167776 0,22405583 ! cytokinesis GO:0000910 84 42 0,000 0,20167776 0,22395399 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,20167776 0,22385224 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,20595023 0,22849065 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,20595023 0,22838693 ! regulation of tube size GO:0035150 76 43 0,000 0,20595023 0,22828331 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,20595023 0,22817978 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,20595023 0,22807634 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,20595023 0,227973 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,20595023 0,22786975 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,20595023 0,2277666 ! ion transmembrane transport GO:0034220 79 43 0,000 0,20595023 0,22766354 ! neuron migration GO:0001764 85 43 0,000 0,20595023 0,22756057 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,20595023 0,22745769 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,21019996 0,23204631 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,21019996 0,23194151 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,21019996 0,23183679 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,21019996 0,23173217 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,21019996 0,23162765 ! hexose transport GO:0008645 68 44 0,000 0,21019996 0,23152322 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,21019996 0,23141888 ! striated muscle contraction GO:0006941 85 44 0,000 0,21019996 0,23131464 ! phagocytosis GO:0006909 105 44 0,000 0,21019996 0,23121049 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,21019996 0,23110643 ! double-strand break repair GO:0006302 85 44 0,000 0,21019996 0,23100247 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,21442705 0,23554195 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,21442705 0,23543609 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,21442705 0,23533032 ! biopolymer methylation GO:0043414 91 45 0,000 0,21442705 0,23522465 ! B cell differentiation GO:0030183 124 45 0,000 0,21442705 0,23511907 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,21442705 0,23501359 ! female gamete generation GO:0007292 71 45 0,000 0,21442705 0,2349082 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,21442705 0,23480291 ! polyol metabolic process GO:0019751 77 45 0,000 0,21442705 0,23469771 ! developmental growth GO:0048589 88 45 0,000 0,21442705 0,23459261 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21863165 0,23908555 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21863165 0,23897858 ! glycolysis GO:0006096 71 46 0,000 0,21863165 0,2388717 ! leukocyte migration GO:0050900 75 46 0,000 0,21863165 0,23876492 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,21863165 0,23865823 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21863165 0,23855164 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,22281386 0,24300636 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,22697379 0,24743283 ! positive regulation of defense response GO:0031349 88 48 0,000 0,22697379 0,24732247 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,22697379 0,24721221 ! mitochondrial transport GO:0006839 94 48 0,000 0,22697379 0,24710204 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,22697379 0,24699197 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,22697379 0,246882 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,22697379 0,24677213 ! male sex differentiation GO:0046661 93 48 0,000 0,22697379 0,24666236 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,22697379 0,24655268 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,22697379 0,2464431 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,22697379 0,24633362 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,22697379 0,24622424 ! methylation GO:0032259 97 48 0,000 0,22697379 0,24611495 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,23111158 0,25049051 ! JNK cascade GO:0007254 106 49 0,000 0,23111158 0,25037942 ! regulation of ion transport GO:0043269 86 50 0,000 0,23522734 0,25472535 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,23522734 0,25461249 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23522734 0,25449973 ! regulation of ossification GO:0030278 123 50 0,000 0,23522734 0,25438707 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,23522734 0,25427451 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,23522734 0,25416205 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,23522734 0,25404969 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,23522734 0,25393743 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,23522734 0,25382526 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,23932118 0,25812876 ! viral infectious cycle GO:0019058 104 51 0,000 0,23932118 0,25801485 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,23932118 0,25790104 ! response to temperature stimulus GO:0009266 84 51 0,000 0,23932118 0,25778732 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,24339322 0,26205802 ! Notch signaling pathway GO:0007219 111 52 0,000 0,24339322 0,26194258 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,24339322 0,26182723 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,24339322 0,26171199 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,24339322 0,26159685 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,24339322 0,26148181 ! excretion GO:0007588 87 52 0,000 0,24339322 0,26136688 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,24339322 0,26125204 ! amino acid activation GO:0043038 98 52 0,000 0,24339322 0,26113731 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24744358 0,2653664 ! chromatin remodeling GO:0006338 122 53 0,000 0,24744358 0,26524996 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,24744358 0,26513363 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24744358 0,26501739 ! vesicle organization GO:0016050 127 53 0,000 0,24744358 0,26490126 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,24744358 0,26478523 ! cartilage development GO:0051216 99 53 0,000 0,24744358 0,2646693 ! regulation of translational initiation GO:0006446 87 54 0,000 0,25147237 0,26886083 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,25147237 0,26874322 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,25147237 0,26862571 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,25147237 0,2685083 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,25147237 0,268391 ! membrane fusion GO:0006944 122 54 0,000 0,25147237 0,2682738 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,25147237 0,2681567 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,25147237 0,2680397 ! regulation of cell shape GO:0008360 142 54 0,000 0,25147237 0,26792281 ! RNA catabolic process GO:0006401 103 55 0,000 0,2554797 0,27207363 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,2554797 0,27195508 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,2554797 0,27183664 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,2554797 0,27171829 ! cell recognition GO:0008037 98 55 0,000 0,2554797 0,27160005 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,2554797 0,27148191 ! cell maturation GO:0048469 107 55 0,000 0,2554797 0,27136388 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,2554797 0,27124594 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,25946569 0,27535825 ! glucose catabolic process GO:0006007 88 56 0,000 0,25946569 0,27523868 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,26343046 0,27932318 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,26343046 0,279202 ! regulation of actin filament length GO:0030832 118 58 0,000 0,26737411 0,28325886 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,26737411 0,28313608 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26737411 0,2830134 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26737411 0,28289084 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,26737411 0,28276837 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,26737411 0,28264601 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26737411 0,28252376 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,26737411 0,28240162 ! nuclear export GO:0051168 110 59 0,000 0,27129675 0,2864209 ! establishment of organelle localization GO:0051656 122 59 0,000 0,27129675 0,28629717 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,2751985 0,29028926 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,2751985 0,29016398 ! adult behavior GO:0030534 104 60 0,000 0,2751985 0,2900388 ! positive regulation of secretion GO:0051047 110 61 0,000 0,27907947 0,29400222 ! regulation of cellular component size GO:0032535 125 61 0,000 0,27907947 0,29387549 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27907947 0,29374887 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27907947 0,29362237 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,27907947 0,29349597 ! regulation of heart contraction GO:0008016 123 61 0,000 0,27907947 0,29336968 ! camera-type eye development GO:0043010 126 61 0,000 0,27907947 0,2932435 ! proton transport GO:0015992 117 61 0,000 0,27907947 0,29311743 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,27907947 0,29299146 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,28293976 0,2969166 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,28293976 0,29678911 ! tRNA processing GO:0008033 102 62 0,000 0,28293976 0,29666174 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,2867795 0,30055869 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,2867795 0,30042981 ! hydrogen transport GO:0006818 121 64 0,000 0,29059878 0,30430039 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,29059878 0,30417002 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,29439771 0,3080144 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,29439771 0,30788254 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,29439771 0,3077508 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,29439771 0,30761917 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,29439771 0,30748765 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29817641 0,31130127 ! gonad development GO:0008406 115 66 0,000 0,29817641 0,31116829 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,30193498 0,31495609 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,30193498 0,31482166 ! secondary metabolic process GO:0019748 125 67 0,000 0,30193498 0,31468735 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,30193498 0,31455316 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,30567353 0,3183122 ! hexose catabolic process GO:0019320 113 68 0,000 0,30567353 0,31817658 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30567353 0,31804107 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,30567353 0,31790567 ! regulation of lipase activity GO:0060191 137 68 0,000 0,30567353 0,31777039 ! adaptive immune response GO:0002250 126 68 0,000 0,30567353 0,31763523 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! homeostasis of number of cells GO:0048872 131 69 0,000 0,30939215 0,32136268 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,30939215 0,32122611 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30939215 0,32108965 ! developmental maturation GO:0021700 128 69 0,000 0,30939215 0,3209533 ! single fertilization GO:0007338 83 69 0,000 0,30939215 0,32081708 ! cell redox homeostasis GO:0045454 114 70 0,000 0,31309097 0,32451474 ! germ cell development GO:0007281 133 70 0,000 0,31309097 0,32437711 ! activation of immune response GO:0002253 120 70 0,000 0,31309097 0,32423961 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,31309097 0,32410222 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,31677008 0,32777183 ! appendage morphogenesis GO:0035107 150 72 0,000 0,32042958 0,33141807 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,32042958 0,33127781 ! B cell activation GO:0042113 179 72 0,000 0,32042958 0,33113768 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,32042958 0,33099766 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,32042958 0,33085777 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,32042958 0,33071799 ! appendage development GO:0048736 151 73 0,000 0,32406959 0,33433362 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,32406959 0,33419249 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,32406959 0,33405148 ! regulation of immune effector process GO:0002697 156 73 0,000 0,32406959 0,33391059 ! acute inflammatory response GO:0002526 118 74 0,000 0,32769021 0,33749881 ! amino acid transport GO:0006865 148 74 0,000 0,32769021 0,33735658 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,32769021 0,33721448 ! organelle localization GO:0051640 155 74 0,000 0,32769021 0,33707249 ! transition metal ion transport GO:0000041 143 75 0,000 0,33129153 0,3406335 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,33129153 0,3404902 ! rhythmic process GO:0048511 142 75 0,000 0,33129153 0,34034701 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,33487366 0,34388245 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,33487366 0,34373796 ! regulation of blood pressure GO:0008217 134 76 0,000 0,33487366 0,34359359 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,33487366 0,34344935 ! amine catabolic process GO:0009310 136 77 0,000 0,3384367 0,34695798 ! neurotransmitter transport GO:0006836 142 77 0,000 0,3384367 0,34681244 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,3384367 0,34666703 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,3384367 0,34652174 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,34198076 0,35000377 ! antigen processing and presentation GO:0019882 117 78 0,000 0,34198076 0,3498572 ! fertilization GO:0009566 99 78 0,000 0,34198076 0,34971075 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,34550593 0,35316777 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,34550593 0,35302007 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,34550593 0,35287248 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34901231 0,35630467 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,34901231 0,35615584 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,34901231 0,35600713 ! muscle cell differentiation GO:0042692 178 81 0,000 0,35250001 0,35941466 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,35250001 0,35926471 ! protein import into nucleus GO:0006606 174 82 0,000 0,35596911 0,3626491 ! exocytosis GO:0006887 153 83 0,000 0,35941973 0,36601184 ! response to drug GO:0042493 149 83 0,000 0,35941973 0,36585934 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35941973 0,36570696 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,35941973 0,36555471 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35941973 0,36540258 ! nuclear import GO:0051170 177 83 0,000 0,35941973 0,36525059 ! T cell activation GO:0042110 189 84 0,000 0,36285196 0,36858517 ! response to nutrient GO:0007584 135 84 0,000 0,36285196 0,36843198 ! digestion GO:0007586 130 84 0,000 0,36285196 0,36827891 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,3662659 0,37158953 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,3662659 0,37143528 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,37303927 0,37814728 ! alcohol catabolic process GO:0046164 142 87 0,000 0,37303927 0,37799044 ! nucleosome assembly GO:0006334 126 87 0,000 0,37303927 0,37783373 ! cellular respiration GO:0045333 143 88 0,000 0,37639891 0,38107855 ! amine biosynthetic process GO:0009309 146 88 0,000 0,37639891 0,38092068 ! sensory perception of smell GO:0007608 117 88 0,000 0,37639891 0,38076295 ! chromatin assembly GO:0031497 128 88 0,000 0,37639891 0,38060535 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,37639891 0,38044788 ! cellular defense response GO:0006968 123 89 0,000 0,37974063 0,38366682 ! protein localization in nucleus GO:0034504 192 89 0,000 0,37974063 0,38350821 ! regulation of neurological system process GO:0031644 175 89 0,000 0,37974063 0,38334974 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,38306454 0,38654551 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,38306454 0,38638591 ! response to unfolded protein GO:0006986 139 90 0,000 0,38306454 0,38622645 ! defense response to bacterium GO:0042742 112 91 0,000 0,38637074 0,38939922 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,3896593 0,39255162 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,39293034 0,39568377 ! amine transport GO:0015837 181 93 0,000 0,39293034 0,39552073 ! vitamin metabolic process GO:0006766 153 93 0,000 0,39293034 0,39535783 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,39618393 0,39846741 ! female pregnancy GO:0007565 166 94 0,000 0,39618393 0,39830344 ! sterol metabolic process GO:0016125 166 94 0,000 0,39618393 0,39813959 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,39618393 0,39797588 ! regulation of defense response GO:0031347 171 95 0,000 0,39942018 0,40106186 ! nucleosome organization GO:0034728 143 95 0,000 0,39942018 0,40089709 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,39942018 0,40073245 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39942018 0,40056794 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,39942018 0,40040357 ! response to protein stimulus GO:0051789 158 96 0,000 0,40263918 0,40346494 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,40584101 0,4065066 ! leukocyte differentiation GO:0002521 232 98 0,000 0,40902577 0,40952867 ! forebrain development GO:0030900 210 98 0,000 0,40902577 0,4093609 ! mRNA transport GO:0051028 185 100 0,000 0,41534444 0,41551452 ! positive regulation of immune response GO:0050778 175 100 0,000 0,41534444 0,41534444