pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6877-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! DNA damage checkpoint GO:0000077 71 33 6,000 1,276E-09 3,07E-06 ! regulation of DNA replication GO:0006275 101 56 7,000 2,276E-09 2,738E-06 ! DNA integrity checkpoint GO:0031570 75 36 6,000 2,454E-09 1,968E-06 ! negative regulation of DNA replication GO:0008156 42 25 5,000 9,046E-09 5,441E-06 ! regulation of DNA metabolic process GO:0051052 178 97 8,000 1,108E-08 5,331E-06 ! negative regulation of DNA metabolic process GO:0051053 61 35 5,000 7,87E-08 3,156E-05 ! DNA damage response, signal transduction GO:0042770 128 60 6,000 9,999E-08 3,437E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 3,000 1,031E-07 3,101E-05 ! negative regulation of DNA replication initiation GO:0032297 9 8 3,000 1,031E-07 2,757E-05 GO:0000076|DNA replication checkpoint, ! mitotic cell cycle checkpoint GO:0007093 76 38 5,000 1,318E-07 3,171E-05 ! cell cycle checkpoint GO:0000075 137 69 6,000 2,664E-07 5,826E-05 ! regulation of DNA replication initiation GO:0030174 14 10 3,000 3,063E-07 6,142E-05 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 2,000 2,41E-06 4,461E-04 GO:0022011|myelination in the peripheral nervous system, ! filopodium assembly GO:0046847 32 16 3,000 2,578E-06 4,43E-04 ! microspike assembly GO:0030035 36 17 3,000 3,354E-06 5,38E-04 ! nuclear migration GO:0007097 12 6 2,000 4,798E-06 7,215E-04 ! astrocyte development GO:0014002 15 6 2,000 4,798E-06 6,79E-04 ! Schwann cell development GO:0014044 15 6 2,000 4,798E-06 6,413E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 4,798E-06 6,076E-04 GO:0031272|regulation of pseudopodium assembly, ! negative regulation of neuroblast proliferation GO:0007406 21 6 2,000 4,798E-06 5,772E-04 ! prostate gland development GO:0030850 13 7 2,000 8,357E-06 9,575E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 8,357E-06 9,14E-04 ! macrophage differentiation GO:0030225 11 7 2,000 8,357E-06 8,743E-04 ! Schwann cell differentiation GO:0014037 19 8 2,000 1,331E-05 1,334E-03 ! astrocyte differentiation GO:0048708 18 8 2,000 1,331E-05 1,281E-03 ! ER overload response GO:0006983 12 8 2,000 1,331E-05 1,232E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,331E-05 1,186E-03 ! protein tetramerization GO:0051262 52 24 3,000 1,447E-05 1,243E-03 ! myelination GO:0042552 45 25 3,000 1,714E-05 1,422E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 1,714E-05 1,375E-03 ! gland development GO:0048732 206 88 5,000 1,995E-05 1,548E-03 ! response to UV GO:0009411 104 53 4,000 2,075E-05 1,56E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 2,734E-05 1,993E-03 ! regulation of bone resorption GO:0045124 25 10 2,000 2,826E-05 2E-03 ! establishment of organelle localization GO:0051656 109 59 4,000 3,511E-05 2,413E-03 ! ensheathment of neurons GO:0007272 57 30 3,000 3,624E-05 2,422E-03 GO:0008366|axon ensheathment, ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 3,811E-05 2,478E-03 ! nucleus localization GO:0051647 19 11 2,000 3,868E-05 2,449E-03 ! regulation of homeostatic process GO:0032844 134 62 4,000 4,469E-05 2,757E-03 ! peripheral nervous system development GO:0007422 64 32 3,000 4,708E-05 2,832E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 5,133E-05 3,012E-03 ! tyrosine metabolic process GO:0006570 16 12 2,000 5,133E-05 2,94E-03 ! autonomic nervous system development GO:0048483 24 12 2,000 5,133E-05 2,872E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 5,133E-05 2,807E-03 ! cell projection assembly GO:0030031 120 66 4,000 6,049E-05 3,234E-03 ! urogenital system development GO:0001655 137 69 4,000 7,492E-05 3,919E-03 ! stem cell development GO:0048864 43 14 2,000 8,414E-05 4,307E-03 GO:0019827|stem cell maintenance, ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 8,414E-05 4,218E-03 ! regulation of action potential in neuron GO:0019228 73 39 3,000 1,041E-04 5,11E-03 ! G1/S transition checkpoint GO:0031575 40 15 2,000 1,047E-04 5,038E-03 ! organelle localization GO:0051640 136 74 4,000 1,047E-04 4,939E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 2,000 1,283E-04 5,934E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 1,283E-04 5,822E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,395E-04 6,218E-03 ! gene silencing by RNA GO:0031047 36 17 2,000 1,55E-04 6,782E-03 ! glial cell development GO:0021782 27 17 2,000 1,55E-04 6,661E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,55E-04 6,544E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 1,831E-04 7,594E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,995E-04 8,136E-03 ! pigmentation GO:0043473 100 46 3,000 1,995E-04 8E-03 ! cerebral cortex development GO:0021987 36 19 2,000 2,189E-04 8,633E-03 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 2,189E-04 8,494E-03 ! regulation of action potential GO:0001508 95 49 3,000 2,553E-04 9,749E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,563E-04 9,636E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,563E-04 9,488E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,563E-04 9,344E-03 ! stem cell differentiation GO:0048863 53 20 2,000 2,563E-04 9,204E-03 ! regulation of cell projection organization GO:0031344 121 50 3,000 2,761E-04 9,769E-03 ! transcription initiation GO:0006352 153 94 4,000 3,225E-04 0,0112441 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,431E-04 0,01179161 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,431E-04 0,01162553 ! aromatic amino acid family metabolic process GO:0009072 32 22 2,000 3,431E-04 0,01146406 ! leukocyte differentiation GO:0002521 202 96 4,000 3,555E-04 0,01171595 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,869E-04 0,01257976 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,869E-04 0,01241203 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,869E-04 0,01224872 ! lymph vessel development GO:0001945 10 5 1,000 3,869E-04 0,01208964 ! smooth muscle tissue development GO:0048745 28 5 1,000 3,869E-04 0,01193465 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,869E-04 0,01178358 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 1,000 3,869E-04 0,01163628 ! microvillus organization GO:0032528 7 5 1,000 3,869E-04 0,01149262 GO:0030033|microvillus assembly, ! melanin biosynthetic process from tyrosine GO:0006583 6 5 1,000 3,869E-04 0,01135247 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,869E-04 0,01121569 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,869E-04 0,01108217 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,869E-04 0,0109518 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,869E-04 0,01082445 ! forebrain morphogenesis GO:0048853 13 5 1,000 3,869E-04 0,01070003 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,869E-04 0,01057844 ! regulation of sensory perception GO:0051931 7 5 1,000 3,869E-04 0,01045958 GO:0051930|regulation of sensory perception of pain, ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 3,927E-04 0,01049835 ! nucleotide-excision repair GO:0006289 83 56 3,000 4,276E-04 0,01130652 ! pallium development GO:0021543 49 24 2,000 4,467E-04 0,01168322 ! regulation of intracellular transport GO:0032386 101 57 3,000 4,577E-04 0,01184043 ! positive regulation of cell migration GO:0030335 126 57 3,000 4,577E-04 0,01171446 ! negative regulation of cell development GO:0010721 73 25 2,000 5,053E-04 0,01279793 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 2,000 5,053E-04 0,01266462 ! skeletal system morphogenesis GO:0048705 105 59 3,000 5,222E-04 0,01295284 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 5,686E-04 0,0139598 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,686E-04 0,01381879 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 5,686E-04 0,0136806 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 5,78E-04 0,01376814 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 5,78E-04 0,01363316 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 1,000 5,78E-04 0,0135008 ! nucleoside salvage GO:0043174 9 6 1,000 5,78E-04 0,01337098 GO:0006166|purine ribonucleoside salvage, ! male sex determination GO:0030238 15 6 1,000 5,78E-04 0,01324364 ! establishment of spindle localization GO:0051293 12 6 1,000 5,78E-04 0,0131187 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 5,78E-04 0,01299609 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 1,000 5,78E-04 0,01287576 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 6,367E-04 0,01405491 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 6,367E-04 0,01392714 ! base-excision repair GO:0006284 41 27 2,000 6,367E-04 0,01380167 ! regulation of chromosome organization GO:0033044 42 27 2,000 6,367E-04 0,01367844 ! positive regulation of cell motion GO:0051272 146 64 3,000 7,115E-04 0,01514858 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 7,881E-04 0,01663367 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 7,881E-04 0,01648903 ! regulation of helicase activity GO:0051095 15 7 1,000 8,058E-04 0,01671355 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,058E-04 0,0165707 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 8,058E-04 0,01643027 ! mRNA stabilization GO:0048255 18 7 1,000 8,058E-04 0,0162922 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 8,058E-04 0,01615643 ! regulation of dopamine metabolic process GO:0042053 11 7 1,000 8,058E-04 0,01602291 GO:0042069|regulation of catecholamine metabolic process, ! adrenal gland development GO:0030325 17 7 1,000 8,058E-04 0,01589157 ! purine salvage GO:0043101 10 7 1,000 8,058E-04 0,01576237 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 8,058E-04 0,01563525 ! B cell lineage commitment GO:0002326 21 7 1,000 8,058E-04 0,01551017 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 8,058E-04 0,01538708 ! T cell lineage commitment GO:0002360 16 7 1,000 8,058E-04 0,01526592 ! response to tumor cell GO:0002347 13 7 1,000 8,058E-04 0,01514665 ! regulation of respiratory burst GO:0060263 11 7 1,000 8,058E-04 0,01502924 ! melanin biosynthetic process GO:0042438 8 7 1,000 8,058E-04 0,01491363 ! lung development GO:0030324 144 67 3,000 8,458E-04 0,0155347 ! respiratory tube development GO:0030323 150 70 3,000 9,971E-04 0,01817508 ! spindle organization GO:0007051 46 32 2,000 1,055E-03 0,01908763 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,055E-03 0,01894519 ! gene silencing GO:0016458 65 32 2,000 1,055E-03 0,01880485 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,07E-03 0,01892907 ! regulation of cellular amine metabolic process GO:0033238 12 8 1,000 1,07E-03 0,01879091 ! meiotic prophase I GO:0007128 13 8 1,000 1,07E-03 0,01865474 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,07E-03 0,01852053 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,07E-03 0,01838824 ! endothelial cell differentiation GO:0045446 17 8 1,000 1,07E-03 0,01825783 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,07E-03 0,01812925 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 1,07E-03 0,01800248 GO:0006559|L-phenylalanine catabolic process, ! melanin metabolic process GO:0006582 15 8 1,000 1,07E-03 0,01787746 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,07E-03 0,01775417 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,07E-03 0,01763256 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,07E-03 0,01751261 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,07E-03 0,01739428 ! respiratory system development GO:0060541 153 72 3,000 1,108E-03 0,01789142 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,155E-03 0,01853129 ! glial cell differentiation GO:0010001 63 34 2,000 1,261E-03 0,02009732 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,261E-03 0,0199651 ! regulation of developmental growth GO:0048638 15 9 1,000 1,37E-03 0,02154394 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,37E-03 0,02140404 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,37E-03 0,02126595 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,37E-03 0,02112963 ! artery development GO:0060840 24 9 1,000 1,37E-03 0,02099505 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 1,000 1,37E-03 0,02086217 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,37E-03 0,02073096 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,37E-03 0,02060139 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,37E-03 0,02047343 ! receptor clustering GO:0043113 18 9 1,000 1,37E-03 0,02034705 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 1,000 1,37E-03 0,02022223 ! motor axon guidance GO:0008045 16 9 1,000 1,37E-03 0,02009892 ! protein heterooligomerization GO:0051291 16 9 1,000 1,37E-03 0,01997711 ! purine base metabolic process GO:0006144 21 9 1,000 1,37E-03 0,01985676 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,37E-03 0,01973786 ! telencephalon development GO:0021537 68 35 2,000 1,373E-03 0,01966643 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,491E-03 0,02122945 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 3,000 1,492E-03 0,02111715 ! protein oligomerization GO:0051259 139 78 3,000 1,492E-03 0,02099366 ! meiosis I GO:0007127 65 37 2,000 1,615E-03 0,02259554 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,615E-03 0,02246493 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,615E-03 0,02233582 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,705E-03 0,02344732 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,705E-03 0,0233141 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,705E-03 0,02318238 ! COPI coating of Golgi vesicle GO:0048205 19 10 1,000 1,705E-03 0,02305214 GO:0048200|Golgi transport vesicle coating, ! lung alveolus development GO:0048286 26 10 1,000 1,705E-03 0,02292336 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,705E-03 0,02279601 ! polyamine biosynthetic process GO:0006596 12 10 1,000 1,705E-03 0,02267006 ! epithelial cell development GO:0002064 20 10 1,000 1,705E-03 0,0225455 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,705E-03 0,0224223 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,705E-03 0,02230044 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 1,000 1,705E-03 0,0221799 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,705E-03 0,02206065 ! cellular metabolic compound salvage GO:0043094 14 10 1,000 1,705E-03 0,02194268 ! prophase GO:0051324 15 10 1,000 1,705E-03 0,02182596 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,705E-03 0,02171048 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,705E-03 0,02159622 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,705E-03 0,02148315 ! localization within membrane GO:0051668 20 10 1,000 1,705E-03 0,02137125 ! response to hypoxia GO:0001666 171 81 3,000 1,715E-03 0,02138133 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,746E-03 0,02165052 GO:0042593|glucose homeostasis, ! response to oxygen levels GO:0070482 176 83 3,000 1,876E-03 0,02314785 ! negative regulation of muscle development GO:0048635 20 11 1,000 2,076E-03 0,02548185 ! telencephalon cell migration GO:0022029 20 11 1,000 2,076E-03 0,0253525 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,076E-03 0,02522446 ! Golgi vesicle budding GO:0048194 22 11 1,000 2,076E-03 0,0250977 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,076E-03 0,02497221 ! blood vessel remodeling GO:0001974 29 11 1,000 2,076E-03 0,02484797 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,076E-03 0,02472496 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,076E-03 0,02460317 ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 1,000 2,076E-03 0,02448256 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 1,000 2,076E-03 0,02436313 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,076E-03 0,02424487 ! regulation of embryonic development GO:0045995 27 11 1,000 2,076E-03 0,02412774 ! tube morphogenesis GO:0035239 176 86 3,000 2,137E-03 0,02471538 ! gliogenesis GO:0042063 88 41 2,000 2,176E-03 0,02504715 ! T cell differentiation GO:0030217 81 41 2,000 2,176E-03 0,02492788 ! regulation of protein transport GO:0051223 154 87 3,000 2,229E-03 0,02541456 GO:0070201|regulation of establishment of protein localization, ! neuron migration GO:0001764 79 42 2,000 2,332E-03 0,02647032 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 2,421E-03 0,02734941 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,481E-03 0,0278908 ! virus-host interaction GO:0019048 29 12 1,000 2,481E-03 0,02776108 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,481E-03 0,02763255 ! cartilage condensation GO:0001502 20 12 1,000 2,481E-03 0,02750521 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,481E-03 0,02737904 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,481E-03 0,02725403 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,481E-03 0,02713014 ! polyamine metabolic process GO:0006595 17 12 1,000 2,481E-03 0,02700738 ! mitotic spindle organization GO:0007052 21 12 1,000 2,481E-03 0,02688573 ! forebrain cell migration GO:0021885 21 12 1,000 2,481E-03 0,02676516 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 1,000 2,481E-03 0,02664568 ! entry into host cell GO:0030260 32 12 1,000 2,481E-03 0,02652725 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! protein homotetramerization GO:0051289 21 12 1,000 2,481E-03 0,02640987 ! cranial nerve development GO:0021545 20 12 1,000 2,481E-03 0,02629353 ! histone acetylation GO:0016573 26 12 1,000 2,481E-03 0,02617821 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,481E-03 0,02606389 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,481E-03 0,02595057 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,481E-03 0,02583823 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 1,000 2,481E-03 0,02572686 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,496E-03 0,02577235 ! ossification GO:0001503 188 90 3,000 2,522E-03 0,02592689 ! bone development GO:0060348 189 91 3,000 2,625E-03 0,02687297 ! double-strand break repair GO:0006302 81 44 2,000 2,666E-03 0,02718152 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,84E-03 0,02882868 ! regulation of membrane potential GO:0042391 164 93 3,000 2,84E-03 0,02870755 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 2,844E-03 0,02862587 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,92E-03 0,02926992 GO:0000725|recombinational repair, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 2,92E-03 0,02914847 ! response to X-ray GO:0010165 25 13 1,000 2,92E-03 0,02902802 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,92E-03 0,02890857 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,92E-03 0,02879009 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 2,92E-03 0,02867258 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,92E-03 0,02855602 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 2,92E-03 0,02844041 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,92E-03 0,02832573 ! positive regulation of homeostatic process GO:0032846 21 13 1,000 2,92E-03 0,02821197 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 2,92E-03 0,02809913 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,92E-03 0,02798718 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,028E-03 0,02891037 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,028E-03 0,0287961 ! response to insulin stimulus GO:0032868 95 46 2,000 3,028E-03 0,02868273 ! positive regulation of protein transport GO:0051222 72 46 2,000 3,028E-03 0,02857025 ! forebrain development GO:0030900 188 95 3,000 3,066E-03 0,02881999 ! regulation of protein localization GO:0032880 176 97 3,000 3,305E-03 0,03094338 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,392E-03 0,03163503 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 3,392E-03 0,03151288 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 1,000 3,392E-03 0,03139168 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,392E-03 0,03127141 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 3,392E-03 0,03115205 ! response to gamma radiation GO:0010332 28 14 1,000 3,392E-03 0,0310336 ! regulation of RNA stability GO:0043487 32 14 1,000 3,392E-03 0,03091605 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,419E-03 0,03103848 ! activation of caspase activity GO:0006919 84 48 2,000 3,419E-03 0,0309218 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,419E-03 0,03080598 ! endocrine system development GO:0035270 104 49 2,000 3,625E-03 0,03254317 ! cell cycle arrest GO:0007050 213 100 3,000 3,687E-03 0,03297485 ! histone modification GO:0016570 91 50 2,000 3,839E-03 0,03420689 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,898E-03 0,03460794 ! pituitary gland development GO:0021983 29 15 1,000 3,898E-03 0,0344807 ! vesicle coating GO:0006901 33 15 1,000 3,898E-03 0,0343544 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,898E-03 0,03422902 ! histone deacetylation GO:0016575 20 15 1,000 3,898E-03 0,03410455 ! positive regulation of calcium ion transport GO:0051928 19 15 1,000 3,898E-03 0,03398098 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 4,06E-03 0,03526451 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,06E-03 0,03513766 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 2,000 4,06E-03 0,03501172 ! regulation of angiogenesis GO:0045765 114 52 2,000 4,289E-03 0,03685349 ! positive regulation of growth GO:0045927 90 52 2,000 4,289E-03 0,03672234 ! covalent chromatin modification GO:0016569 101 52 2,000 4,289E-03 0,03659212 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 4,289E-03 0,03646282 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,437E-03 0,03758623 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 4,437E-03 0,03745435 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,437E-03 0,03732339 ! positive regulation of ion transport GO:0043270 21 16 1,000 4,437E-03 0,03719334 ! startle response GO:0001964 28 16 1,000 4,437E-03 0,0370642 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 4,437E-03 0,03693595 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,437E-03 0,03680858 ! neuron recognition GO:0008038 35 16 1,000 4,437E-03 0,03668209 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,437E-03 0,03655647 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,437E-03 0,0364317 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 100 53 2,000 4,525E-03 0,0370346 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 5,007E-03 0,04084075 ! signal complex assembly GO:0007172 41 17 1,000 5,007E-03 0,04070278 ! limbic system development GO:0021761 36 17 1,000 5,007E-03 0,04056573 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 5,007E-03 0,0404296 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,007E-03 0,04029439 ! membrane budding GO:0006900 37 17 1,000 5,007E-03 0,04016007 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 5,007E-03 0,04002665 ! nucleobase metabolic process GO:0009112 37 17 1,000 5,007E-03 0,03989411 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,007E-03 0,03976245 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 5,007E-03 0,03963165 ! positive regulation of caspase activity GO:0043280 95 55 2,000 5,022E-03 0,03961548 GO:0010952|positive regulation of peptidase activity, ! RNA elongation GO:0006354 79 55 2,000 5,022E-03 0,03948601 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 5,55E-03 0,04349595 ! regulation of bone remodeling GO:0046850 137 57 2,000 5,55E-03 0,04335473 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,61E-03 0,04368393 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 5,61E-03 0,04354302 ! patterning of blood vessels GO:0001569 39 18 1,000 5,61E-03 0,04340301 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 5,61E-03 0,04326389 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,61E-03 0,04312567 ! aromatic compound catabolic process GO:0019439 27 18 1,000 5,61E-03 0,04298833 ! nerve development GO:0021675 28 18 1,000 5,61E-03 0,04285186 ! regulation of tissue remodeling GO:0034103 140 58 2,000 5,826E-03 0,04435891 ! DNA catabolic process GO:0006308 86 59 2,000 6,11E-03 0,04637552 ! lipid phosphorylation GO:0046834 35 19 1,000 6,245E-03 0,0472466 ! forelimb morphogenesis GO:0035136 32 19 1,000 6,245E-03 0,04709849 ! pigmentation during development GO:0048066 41 19 1,000 6,245E-03 0,04695131 ! cellular response to unfolded protein GO:0034620 33 19 1,000 6,245E-03 0,04680504 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 34 19 1,000 6,245E-03 0,04665969 ! protein export from nucleus GO:0006611 36 19 1,000 6,245E-03 0,04651523 ! visual learning GO:0008542 36 19 1,000 6,245E-03 0,04637166 ! kidney development GO:0001822 122 60 2,000 6,402E-03 0,04739776 ! regulation of protein complex assembly GO:0043254 117 61 2,000 6,703E-03 0,0494701 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 6,703E-03 0,04931882 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,91E-03 0,05068682 ! protein amino acid deacetylation GO:0006476 29 20 1,000 6,91E-03 0,05053276 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,91E-03 0,05037963 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,91E-03 0,05022743 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 6,91E-03 0,05007614 ! cellular response to starvation GO:0009267 33 20 1,000 6,91E-03 0,04992576 ! diencephalon development GO:0021536 34 20 1,000 6,91E-03 0,04977628 ! peptidyl-serine modification GO:0018209 43 20 1,000 6,91E-03 0,0496277 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 6,91E-03 0,04947999 ! negative regulation of T cell activation GO:0050868 40 20 1,000 6,91E-03 0,04933317 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 6,91E-03 0,04918721 ! viral reproductive process GO:0022415 126 62 2,000 7,012E-03 0,04976435 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 7,329E-03 0,05186173 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 7,329E-03 0,05170965 ! hindlimb morphogenesis GO:0035137 43 21 1,000 7,606E-03 0,05350854 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 7,606E-03 0,05335254 ! cell aging GO:0007569 44 21 1,000 7,606E-03 0,05319745 ! regulation of Rho GTPase activity GO:0032319 43 21 1,000 7,606E-03 0,05304325 ! positive regulation of locomotion GO:0040017 39 21 1,000 7,606E-03 0,05288995 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 1,000 7,606E-03 0,05273753 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 7,606E-03 0,05258598 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 7,606E-03 0,05243531 ! myeloid cell differentiation GO:0030099 111 65 2,000 7,988E-03 0,05491219 ! regulation of chemotaxis GO:0050920 40 22 1,000 8,332E-03 0,05711502 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 8,332E-03 0,05695276 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 8,332E-03 0,05679143 ! apoptotic nuclear changes GO:0030262 32 22 1,000 8,332E-03 0,056631 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 8,332E-03 0,05647147 ! sarcomere organization GO:0045214 30 22 1,000 8,332E-03 0,05631285 ! positive regulation of B cell activation GO:0050871 38 22 1,000 8,332E-03 0,05615511 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 8,332E-03 0,05599825 ! protein stabilization GO:0050821 39 22 1,000 8,332E-03 0,05584227 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 8,681E-03 0,0580195 ! negative regulation of cell growth GO:0030308 132 67 2,000 8,681E-03 0,05785878 ! negative regulation of kinase activity GO:0033673 131 68 2,000 9,041E-03 0,06008764 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 9,041E-03 0,05992211 ! viral reproduction GO:0016032 134 68 2,000 9,041E-03 0,05975749 ! positive regulation of DNA replication GO:0045740 43 23 1,000 9,088E-03 0,05990866 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 9,088E-03 0,05974498 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 9,088E-03 0,05958218 ! visual behavior GO:0007632 42 23 1,000 9,088E-03 0,05942027 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 9,088E-03 0,05925924 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 9,088E-03 0,05909908 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 9,088E-03 0,05893979 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 1,000 9,088E-03 0,05878135 ! sex determination GO:0007530 47 23 1,000 9,088E-03 0,05862376 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 9,088E-03 0,05846701 ! negative regulation of catabolic process GO:0009895 50 23 1,000 9,088E-03 0,0583111 ! negative regulation of cell size GO:0045792 134 69 2,000 9,409E-03 0,06020511 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 9,874E-03 0,06301545 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 9,874E-03 0,06284874 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 9,874E-03 0,06268292 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 9,874E-03 0,06251796 ! spinal cord development GO:0021510 47 24 1,000 9,874E-03 0,06235387 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 9,874E-03 0,06219064 ! regulation of behavior GO:0050795 43 24 1,000 9,874E-03 0,06202826 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 9,874E-03 0,06186673 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 9,874E-03 0,06170604 ! reproductive structure development GO:0048608 113 71 2,000 0,01017056 0,06339471 ! regulation of caspase activity GO:0043281 122 72 2,000 0,01056458 0,06568057 ! negative regulation of transferase activity GO:0051348 140 72 2,000 0,01056458 0,06551129 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01068866 0,06611032 ! vasculogenesis GO:0001570 46 25 1,000 0,01068866 0,0659408 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01068866 0,06577216 ! receptor metabolic process GO:0043112 46 25 1,000 0,01068866 0,06560437 ! response to starvation GO:0042594 42 25 1,000 0,01068866 0,06543744 ! osteoblast differentiation GO:0001649 60 25 1,000 0,01068866 0,06527135 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01068866 0,06510611 ! somitogenesis GO:0001756 43 25 1,000 0,01068866 0,0649417 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01068866 0,06477812 ! neural tube closure GO:0001843 49 25 1,000 0,01068866 0,06461536 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 0,01068866 0,06445342 ! learning or memory GO:0007611 147 73 2,000 0,01096735 0,06596863 ! regulation of transcription factor activity GO:0051090 126 74 2,000 0,01137891 0,06827346 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 2,000 0,01137891 0,06810362 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01137891 0,06793463 ! initiation of viral infection GO:0019059 57 26 1,000 0,011532 0,06867818 ! tube lumen formation GO:0035148 50 26 1,000 0,011532 0,0685086 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,011532 0,06833986 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 0,011532 0,06817195 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,011532 0,06800487 GO:0045840|positive regulation of mitosis, ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01179928 0,06941091 ! meiotic cell cycle GO:0051321 122 75 2,000 0,01179928 0,06924162 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01179928 0,06907315 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01222849 0,07141201 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01240362 0,07225933 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01240362 0,07208479 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01240362 0,0719111 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01240362 0,07173823 ! primary neural tube formation GO:0014020 51 27 1,000 0,01240362 0,0715662 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01240362 0,07139499 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01330314 0,07638985 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01356946 0,07773359 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 0,0140343 0,08020554 ! response to metal ion GO:0010038 140 80 2,000 0,0140343 0,08001548 ! regulation of pH GO:0006885 43 29 1,000 0,01423018 0,08094043 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01423018 0,08074953 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01423018 0,08055953 ! cell fate determination GO:0001709 60 29 1,000 0,01423018 0,08037043 ! T cell activation GO:0042110 168 81 2,000 0,01450812 0,08174831 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 0,01499092 0,08427138 ! regulation of cyclase activity GO:0031279 159 82 2,000 0,01499092 0,08407494 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01499092 0,08387942 ! myofibril assembly GO:0030239 47 30 1,000 0,01518435 0,08476463 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01518435 0,08456842 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01518435 0,08437311 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01518435 0,0841787 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01518435 0,08398519 ! eye morphogenesis GO:0048592 60 30 1,000 0,01518435 0,08379256 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01518435 0,08360081 ! regulation of lyase activity GO:0051339 160 83 2,000 0,01548273 0,08504894 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 0,01598355 0,08760007 ! negative regulation of transport GO:0051051 153 84 2,000 0,01598355 0,08740098 ! negative regulation of growth GO:0045926 155 84 2,000 0,01598355 0,08720279 ! iron ion homeostasis GO:0055072 54 31 1,000 0,0161653 0,08799483 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,0161653 0,08779619 GO:0043433|negative regulation of transcription factor activity, ! response to inorganic substance GO:0010035 153 86 2,000 0,01701234 0,09218849 ! mitochondrion organization GO:0007005 148 86 2,000 0,01701234 0,09198133 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,01717264 0,09263987 ! metanephros development GO:0001656 74 32 1,000 0,01717264 0,09243263 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01717264 0,0922263 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01717264 0,0920209 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,01717264 0,09181641 ! muscle cell development GO:0055001 49 32 1,000 0,01717264 0,09161282 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01717264 0,09141014 ! hindbrain development GO:0030902 61 32 1,000 0,01717264 0,09120835 ! regulation of calcium ion transport GO:0051924 53 32 1,000 0,01717264 0,09100745 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01717264 0,09080744 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 0,01754032 0,09254829 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of DNA binding GO:0051101 155 88 2,000 0,01807738 0,09517328 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01820602 0,09564124 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01820602 0,09543287 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01820602 0,0952254 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01862353 0,09719786 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 0,01917877 0,09987905 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01926507 0,10011177 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01926507 0,09989601 ! regulation of muscle development GO:0048634 70 35 1,000 0,02034942 0,10529184 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,02034942 0,10506589 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,02034942 0,10484091 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02034942 0,10461689 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02034942 0,10439383 ! neural tube formation GO:0001841 67 35 1,000 0,02034942 0,10417171 ! vesicle localization GO:0051648 64 35 1,000 0,02034942 0,10395054 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 0,02089912 0,10653239 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02145873 0,1091537 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02145873 0,10892342 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02145873 0,10869411 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,02145873 0,10846576 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02145873 0,10823837 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 0,02209159 0,11119742 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,02209159 0,11096528 ! RNA export from nucleus GO:0006405 56 37 1,000 0,02259264 0,1132456 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,02259264 0,11301016 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02259264 0,1127757 ! actomyosin structure organization GO:0031032 62 37 1,000 0,02259264 0,11254221 ! tissue remodeling GO:0048771 76 37 1,000 0,02259264 0,11230968 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02259264 0,11207812 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02259264 0,11184751 ! regulation of protein stability GO:0031647 73 37 1,000 0,02259264 0,11161784 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02259264 0,11138911 ! pigment metabolic process GO:0042440 80 37 1,000 0,02259264 0,11116132 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,0237508 0,11662128 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,0237508 0,11638376 ! regulation of metal ion transport GO:0010959 63 38 1,000 0,0237508 0,11614721 ! nucleus organization GO:0006997 67 38 1,000 0,0237508 0,11591161 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,0237508 0,11567697 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,0237508 0,11544328 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,0237508 0,11521054 ! glucan metabolic process GO:0044042 62 38 1,000 0,0237508 0,11497872 GO:0006073|cellular glucan metabolic process, ! interphase GO:0051325 213 98 2,000 0,02394868 0,11570385 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02458594 0,11854461 GO:0060538|skeletal muscle organ development, ! mammary gland development GO:0030879 86 39 1,000 0,02493287 0,11997697 ! learning GO:0007612 77 39 1,000 0,02493287 0,11973749 ! ear morphogenesis GO:0042471 60 39 1,000 0,02493287 0,11949897 ! segmentation GO:0035282 67 39 1,000 0,02493287 0,1192614 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02493287 0,11902477 ! negative regulation of binding GO:0051100 72 40 1,000 0,0261385 0,12453314 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,0261385 0,12428703 ! maintenance of protein location GO:0045185 91 40 1,000 0,0261385 0,12404189 ! cytokinesis GO:0000910 72 40 1,000 0,0261385 0,12379771 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02736736 0,12936321 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02736736 0,12910955 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02736736 0,12885689 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02861911 0,13448746 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02989342 0,14020188 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02989342 0,13992911 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02989342 0,1396574 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02989342 0,13938675 ! neural tube development GO:0021915 77 43 1,000 0,02989342 0,13911714 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0309883 0,14393408 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0309883 0,14365675 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0309883 0,14338048 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0309883 0,14310528 ! neuron fate determination GO:0048664 7 5 0,000 0,0309883 0,14283113 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0309883 0,14255803 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0309883 0,14228598 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0309883 0,14201496 ! polyol transport GO:0015791 12 5 0,000 0,0309883 0,14174497 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0309883 0,141476 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0309883 0,14120805 ! response to superoxide GO:0000303 10 5 0,000 0,0309883 0,14094112 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0309883 0,14067519 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0309883 0,14041027 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0309883 0,14014634 ! female meiosis GO:0007143 7 5 0,000 0,0309883 0,1398834 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0309883 0,13962145 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0309883 0,13936047 ! cobalt ion transport GO:0006824 11 5 0,000 0,0309883 0,13910047 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0309883 0,13884144 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0309883 0,13858337 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0309883 0,13832626 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0309883 0,1380701 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0309883 0,13781488 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0309883 0,13756061 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0309883 0,13730728 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0309883 0,13705487 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0309883 0,1368034 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0309883 0,13655284 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0309883 0,1363032 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0309883 0,13605447 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0309883 0,13580665 ! negative chemotaxis GO:0050919 14 5 0,000 0,0309883 0,13555973 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0309883 0,13531371 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0309883 0,13506857 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0309883 0,13482433 ! behavioral response to pain GO:0048266 9 5 0,000 0,0309883 0,13458096 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0309883 0,13433847 ! Notch receptor processing GO:0007220 8 5 0,000 0,0309883 0,13409686 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0309883 0,13385611 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0309883 0,13361622 ! micturition GO:0060073 9 5 0,000 0,0309883 0,13337719 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0309883 0,13313902 ! copulation GO:0007620 9 5 0,000 0,0309883 0,1329017 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0309883 0,13266522 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0309883 0,13242958 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0309883 0,13219477 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0309883 0,1319608 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0309883 0,13172765 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0309883 0,13149533 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0309883 0,13126382 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0309883 0,13103313 ! grooming behavior GO:0007625 6 5 0,000 0,0309883 0,13080325 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0309883 0,13057417 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0309883 0,13034589 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0309883 0,13011842 ! response to protozoan GO:0001562 10 5 0,000 0,0309883 0,12989173 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0309883 0,12966583 ! endochondral ossification GO:0001958 16 5 0,000 0,0309883 0,12944072 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0309883 0,12921638 ! parathyroid gland development GO:0060017 13 5 0,000 0,0309883 0,12899282 ! anagen GO:0042640 6 5 0,000 0,0309883 0,12877004 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0309883 0,12854802 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0309883 0,12832677 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0309883 0,12810627 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0309883 0,12788654 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0309883 0,12766755 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0309883 0,12744932 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0309883 0,12723183 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0309883 0,12701508 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0309883 0,12679907 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0309883 0,12658379 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0309883 0,12636924 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0309883 0,12615542 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0309883 0,12594232 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0309883 0,12572994 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0309883 0,12551827 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0309883 0,12530731 ! histidine catabolic process GO:0006548 6 5 0,000 0,0309883 0,12509707 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0309883 0,12488752 ! valine metabolic process GO:0006573 10 5 0,000 0,0309883 0,12467868 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0309883 0,12447054 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0309883 0,12426309 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0309883 0,12405633 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0309883 0,12385025 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0309883 0,12364486 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0309883 0,12344015 ! polyol catabolic process GO:0046174 7 5 0,000 0,0309883 0,12323612 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0309883 0,12303276 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0309883 0,12283007 ! muscle cell migration GO:0014812 8 5 0,000 0,0309883 0,12262805 ! mitochondrial fission GO:0000266 8 5 0,000 0,0309883 0,12242669 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0309883 0,12222599 ! mRNA transcription GO:0009299 9 5 0,000 0,0309883 0,12202594 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0309883 0,12182656 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0309883 0,12162782 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0309883 0,12142973 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0309883 0,12123228 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0309883 0,12103547 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0309883 0,12083931 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0309883 0,12064377 ! response to food GO:0032094 6 5 0,000 0,0309883 0,12044887 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0309883 0,1202546 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0309883 0,12006095 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0309883 0,11986793 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0309883 0,11967552 ! forebrain neuron development GO:0021884 13 5 0,000 0,0309883 0,11948374 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0309883 0,11929256 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0309883 0,119102 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0309883 0,11891204 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0309883 0,11872269 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0309883 0,11853395 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0309883 0,1183458 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0309883 0,11815824 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0309883 0,11797128 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0309883 0,11778492 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0309883 0,11759914 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0309883 0,11741394 ! basic amino acid transport GO:0015802 11 5 0,000 0,0309883 0,11722933 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0309883 0,11704529 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0309883 0,11686184 ! depyrimidination GO:0045008 10 5 0,000 0,0309883 0,11667895 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0309883 0,11649664 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0309883 0,1163149 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0309883 0,11613373 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0309883 0,11595311 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0309883 0,11577306 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0309883 0,11559357 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0309883 0,11541463 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0309883 0,11523625 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0309883 0,11505841 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0309883 0,11488113 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0309883 0,11470439 ! response to arsenic GO:0046685 10 5 0,000 0,0309883 0,11452819 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0309883 0,11435253 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0309883 0,11417741 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0309883 0,11400283 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0309883 0,11382878 ! response to cadmium ion GO:0046686 7 5 0,000 0,0309883 0,11365526 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0309883 0,11348227 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0309883 0,11330981 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0309883 0,11313786 ! decidualization GO:0046697 11 5 0,000 0,0309883 0,11296644 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0309883 0,11279554 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0309883 0,11262515 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0309883 0,11245528 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0309883 0,11228592 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0309883 0,11211707 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0309883 0,11194873 ! neural tube patterning GO:0021532 7 5 0,000 0,0309883 0,11178089 ! embryonic cleavage GO:0040016 6 5 0,000 0,0309883 0,11161355 ! peroxisome fission GO:0016559 5 5 0,000 0,0309883 0,11144671 ! histone demethylation GO:0016577 10 5 0,000 0,0309883 0,11128038 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0309883 0,11111453 ! mitotic recombination GO:0006312 9 5 0,000 0,0309883 0,11094918 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0309883 0,11078433 ! metaphase plate congression GO:0051310 7 5 0,000 0,0309883 0,11061996 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0309883 0,11045608 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0309883 0,11029268 ! enteric nervous system development GO:0048484 8 5 0,000 0,0309883 0,11012977 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0309883 0,10996733 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0309883 0,10980538 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0309883 0,1096439 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0309883 0,1094829 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0309883 0,10932236 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0309883 0,1091623 ! plasminogen activation GO:0031639 5 5 0,000 0,0309883 0,10900271 ! B cell homeostasis GO:0001782 13 5 0,000 0,0309883 0,10884358 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0309883 0,10868492 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0309883 0,10852671 ! metaphase GO:0051323 8 5 0,000 0,0309883 0,10836897 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0309883 0,10821169 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0309883 0,10805486 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0309883 0,10789848 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0309883 0,10774256 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0309883 0,10758709 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0309883 0,10743206 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0309883 0,10727748 ! response to redox state GO:0051775 5 5 0,000 0,0309883 0,10712335 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0309883 0,10696966 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0309883 0,10681641 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0309883 0,10666359 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0309883 0,10651122 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0309883 0,10635928 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0309883 0,10620777 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0309883 0,10605669 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0309883 0,10590604 ! striatum development GO:0021756 9 5 0,000 0,0309883 0,10575582 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0309883 0,10560602 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0309883 0,10545665 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0309883 0,1053077 ! glial cell migration GO:0008347 11 5 0,000 0,0309883 0,10515917 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0309883 0,10501106 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0309883 0,10486336 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0309883 0,10471608 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0309883 0,10456922 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0309883 0,10442276 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0309883 0,10427672 ! neuroprotection GO:0043526 6 5 0,000 0,0309883 0,10413108 ! neural plate development GO:0001840 8 5 0,000 0,0309883 0,10398585 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0309883 0,10384102 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0309883 0,1036966 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0309883 0,10355257 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0309883 0,10340895 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0309883 0,10326572 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0309883 0,10312289 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0309883 0,10298046 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0309883 0,10283842 ! spindle assembly GO:0051225 6 5 0,000 0,0309883 0,10269677 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0309883 0,1025555 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0309883 0,10241463 ! drug metabolic process GO:0017144 6 5 0,000 0,0309883 0,10227415 ! stem cell division GO:0017145 11 5 0,000 0,0309883 0,10213404 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0309883 0,10199433 ! organ regeneration GO:0031100 7 5 0,000 0,0309883 0,10185499 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0309883 0,10171603 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0309883 0,10157745 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0309883 0,10143925 ! B cell differentiation GO:0030183 107 44 1,000 0,03118995 0,10196063 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03118995 0,10182229 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03250839 0,10598264 ! cell growth GO:0016049 84 45 1,000 0,03250839 0,10583922 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 0,03384841 0,11005306 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,03384841 0,10990454 ! response to calcium ion GO:0051592 81 47 1,000 0,03520968 0,11417048 ! endosome transport GO:0016197 108 47 1,000 0,03520968 0,11401682 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03520968 0,11386357 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03520968 0,11371074 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 0,03520968 0,11355831 ! protein homooligomerization GO:0051260 76 47 1,000 0,03520968 0,11340629 ! mitochondrial transport GO:0006839 82 48 1,000 0,0365919 0,1177007 ! cellular component disassembly GO:0022411 86 48 1,000 0,0365919 0,11754355 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,0365919 0,11738683 ! positive regulation of lyase activity GO:0051349 104 48 1,000 0,0365919 0,11723052 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0365919 0,11707463 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03707037 0,11844795 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03707037 0,11829086 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03707037 0,11813418 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03707037 0,11797792 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03707037 0,11782207 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03707037 0,11766663 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03707037 0,1175116 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03707037 0,11735698 ! sleep GO:0030431 13 6 0,000 0,03707037 0,11720277 ! response to oxygen radical GO:0000305 11 6 0,000 0,03707037 0,11704896 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03707037 0,11689555 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03707037 0,11674255 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03707037 0,11658994 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03707037 0,11643774 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03707037 0,11628593 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03707037 0,11613451 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03707037 0,11598349 ! forebrain regionalization GO:0021871 8 6 0,000 0,03707037 0,11583286 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03707037 0,11568263 ! male meiosis GO:0007140 7 6 0,000 0,03707037 0,11553278 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03707037 0,11538332 ! response to zinc ion GO:0010043 9 6 0,000 0,03707037 0,11523425 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03707037 0,11508556 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03707037 0,11493725 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03707037 0,11478933 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03707037 0,11464178 ! malate metabolic process GO:0006108 11 6 0,000 0,03707037 0,11449462 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03707037 0,11434783 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03707037 0,11420142 ! protein refolding GO:0042026 15 6 0,000 0,03707037 0,11405538 ! opsonization GO:0008228 8 6 0,000 0,03707037 0,11390971 ! mating behavior GO:0007617 7 6 0,000 0,03707037 0,11376442 ! neuron remodeling GO:0016322 15 6 0,000 0,03707037 0,1136195 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03707037 0,11347494 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03707037 0,11333076 ! equilibrioception GO:0050957 14 6 0,000 0,03707037 0,11318694 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03707037 0,11304348 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03707037 0,11290039 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03707037 0,11275766 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03707037 0,11261529 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03707037 0,11247327 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03707037 0,11233162 ! toxin metabolic process GO:0009404 11 6 0,000 0,03707037 0,11219032 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03707037 0,11204938 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03707037 0,11190879 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03707037 0,11176855 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03707037 0,11162867 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03707037 0,11148913 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03707037 0,11134994 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03707037 0,1112111 ! thymic T cell selection GO:0045061 12 6 0,000 0,03707037 0,11107261 ! protein lipoylation GO:0009249 10 6 0,000 0,03707037 0,11093446 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03707037 0,11079665 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03707037 0,11065919 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03707037 0,11052206 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03707037 0,11038528 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03707037 0,11024883 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03707037 0,11011272 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03707037 0,10997695 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03707037 0,10984151 ! hyperosmotic response GO:0006972 9 6 0,000 0,03707037 0,1097064 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03707037 0,10957163 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03707037 0,10943719 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03707037 0,10930307 ! urea metabolic process GO:0019627 7 6 0,000 0,03707037 0,10916928 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03707037 0,10903583 ! neutrophil activation GO:0042119 8 6 0,000 0,03707037 0,10890269 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03707037 0,10876989 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03707037 0,1086374 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03707037 0,10850524 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03707037 0,1083734 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03707037 0,10824188 ! neuron apoptosis GO:0051402 9 6 0,000 0,03707037 0,10811067 ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03707037 0,10797979 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03707037 0,10784922 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03707037 0,10771897 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03707037 0,10758903 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03707037 0,1074594 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03707037 0,10733009 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03707037 0,10720109 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03707037 0,1070724 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03707037 0,10694401 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03707037 0,10681594 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03707037 0,10668816 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03707037 0,1065607 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03707037 0,10643354 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03707037 0,10630668 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03707037 0,10618013 ! monocyte differentiation GO:0030224 12 6 0,000 0,03707037 0,10605387 ! response to UV-C GO:0010225 11 6 0,000 0,03707037 0,10592792 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03707037 0,10580226 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03707037 0,1056769 ! interaction with symbiont GO:0051702 13 6 0,000 0,03707037 0,10555184 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03707037 0,10542708 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03707037 0,1053026 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03707037 0,10517843 ! response to copper ion GO:0046688 10 6 0,000 0,03707037 0,10505454 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03707037 0,10493095 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03707037 0,10480764 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03707037 0,10468463 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03707037 0,10456191 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03707037 0,10443947 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03707037 0,10431732 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03707037 0,10419545 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03707037 0,10407387 ! hair follicle maturation GO:0048820 7 6 0,000 0,03707037 0,10395257 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03707037 0,10383156 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03707037 0,10371082 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03707037 0,10359037 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03707037 0,10347019 ! subpallium development GO:0021544 10 6 0,000 0,03707037 0,1033503 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03707037 0,10323068 ! histone ubiquitination GO:0016574 8 6 0,000 0,03707037 0,10311134 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03707037 0,10299227 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03707037 0,10287348 ! G2 phase GO:0051319 16 6 0,000 0,03707037 0,10275496 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03707037 0,10263672 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03707037 0,10251874 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03707037 0,10240104 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03707037 0,10228361 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03707037 0,10216644 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03707037 0,10204955 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03707037 0,10193292 ! receptor internalization GO:0031623 10 6 0,000 0,03707037 0,10181656 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03707037 0,10170046 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03707037 0,10158463 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03707037 0,10146906 ! protein deubiquitination GO:0016579 14 6 0,000 0,03707037 0,10135376 ! protein destabilization GO:0031648 9 6 0,000 0,03707037 0,10123871 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03707037 0,10112393 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03707037 0,10100941 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03707037 0,10089514 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03707037 0,10078114 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03707037 0,10066739 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03707037 0,1005539 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03707037 0,10044066 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03707037 0,10032768 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03707037 0,10021495 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03707037 0,10010248 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03707037 0,09999025 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03707037 0,09987828 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03707037 0,09976656 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03707037 0,09965509 ! catecholamine transport GO:0051937 9 6 0,000 0,03707037 0,09954387 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03707037 0,09943289 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03707037 0,09932217 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03707037 0,09921169 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03707037 0,09910145 ! maternal placenta development GO:0001893 12 6 0,000 0,03707037 0,09899146 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03707037 0,09888171 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03707037 0,09877221 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03707037 0,09866295 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03707037 0,09855393 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03707037 0,09844515 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03707037 0,09833661 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03707037 0,09822831 ! regulation of ion transport GO:0043269 77 49 1,000 0,03799475 0,10056697 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,03799475 0,10045646 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03799475 0,10034619 ! neuromuscular process GO:0050905 99 50 1,000 0,03941792 0,10399071 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03941792 0,10387681 ! positive regulation of binding GO:0051099 78 51 1,000 0,04086111 0,10756217 ! viral infectious cycle GO:0019058 99 51 1,000 0,04086111 0,10744461 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,04086111 0,10732731 ! vesicle organization GO:0016050 107 51 1,000 0,04086111 0,10721027 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,04086111 0,10709349 ! amino acid activation GO:0043038 92 52 1,000 0,042324 0,11080689 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 0,042324 0,11068645 ! synapse organization GO:0050808 85 52 1,000 0,042324 0,11056627 ! tRNA transcription GO:0009304 14 7 0,000 0,04311446 0,11250911 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04311446 0,11238721 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04311446 0,11226558 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04311446 0,11214421 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04311446 0,1120231 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04311446 0,11190226 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04311446 0,11178168 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04311446 0,11166135 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04311446 0,11154128 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04311446 0,11142148 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04311446 0,11130193 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04311446 0,11118263 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04311446 0,11106359 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04311446 0,11094481 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04311446 0,11082628 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04311446 0,110708 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04311446 0,11058997 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04311446 0,1104722 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04311446 0,11035468 ! glycolipid transport GO:0046836 10 7 0,000 0,04311446 0,1102374 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04311446 0,11012038 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04311446 0,1100036 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04311446 0,10988707 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04311446 0,10977079 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04311446 0,10965475 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04311446 0,10953896 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04311446 0,10942341 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04311446 0,10930811 ! pericardium development GO:0060039 14 7 0,000 0,04311446 0,10919305 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04311446 0,10907823 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04311446 0,10896365 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04311446 0,10884931 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04311446 0,10873521 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04311446 0,10862136 ! lipoprotein transport GO:0042953 14 7 0,000 0,04311446 0,10850774 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04311446 0,10839435 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04311446 0,10828121 ! rhythmic behavior GO:0007622 15 7 0,000 0,04311446 0,10816829 ! estrogen metabolic process GO:0008210 17 7 0,000 0,04311446 0,10805562 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04311446 0,10794318 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04311446 0,10783097 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04311446 0,107719 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04311446 0,10760726 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04311446 0,10749575 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04311446 0,10738447 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04311446 0,10727342 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04311446 0,1071626 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04311446 0,10705201 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04311446 0,10694164 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04311446 0,10683151 ! spinal cord patterning GO:0021511 13 7 0,000 0,04311446 0,1067216 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04311446 0,10661192 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04311446 0,10650246 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04311446 0,10639323 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04311446 0,10628422 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04311446 0,10617543 ! ovulation GO:0030728 9 7 0,000 0,04311446 0,10606687 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04311446 0,10595852 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04311446 0,1058504 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04311446 0,1057425 ! microtubule nucleation GO:0007020 20 7 0,000 0,04311446 0,10563482 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04311446 0,10552736 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04311446 0,10542012 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04311446 0,10531309 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04311446 0,10520628 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04311446 0,10509969 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04311446 0,10499331 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04311446 0,10488715 ! galactose metabolic process GO:0006012 13 7 0,000 0,04311446 0,10478121 ! vesicle fusion GO:0006906 17 7 0,000 0,04311446 0,10467547 ! response to dietary excess GO:0002021 8 7 0,000 0,04311446 0,10456995 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04311446 0,10446465 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04311446 0,10435955 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04311446 0,10425467 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04311446 0,10414999 ! organ growth GO:0035265 15 7 0,000 0,04311446 0,10404553 ! nucleoside transport GO:0015858 8 7 0,000 0,04311446 0,10394128 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04311446 0,10383723 ! parturition GO:0007567 14 7 0,000 0,04311446 0,10373339 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04311446 0,10362977 ! rRNA modification GO:0000154 14 7 0,000 0,04311446 0,10352634 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04311446 0,10342313 ! spindle checkpoint GO:0031577 15 7 0,000 0,04311446 0,10332011 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04311446 0,10321731 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04311446 0,10311471 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04311446 0,10301231 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04311446 0,10291011 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04311446 0,10280812 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04311446 0,10270633 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04311446 0,10260474 ! fibrinolysis GO:0042730 10 7 0,000 0,04311446 0,10250335 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04311446 0,10240217 ! eating behavior GO:0042755 7 7 0,000 0,04311446 0,10230118 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04311446 0,10220039 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04311446 0,1020998 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04311446 0,1019994 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04311446 0,10189921 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04311446 0,10179921 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04311446 0,10169941 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04311446 0,1015998 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04311446 0,10150039 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04311446 0,10140117 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04311446 0,10130214 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04311446 0,10120331 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04311446 0,10110467 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04311446 0,10100623 ! regulation of meiosis GO:0040020 12 7 0,000 0,04311446 0,10090797 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04311446 0,10080991 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04311446 0,10071203 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04311446 0,10061435 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04311446 0,10051686 ! transcription termination GO:0006353 13 7 0,000 0,04311446 0,10041955 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04311446 0,10032243 ! anaphase GO:0051322 17 7 0,000 0,04311446 0,1002255 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04311446 0,10012876 ! axonal fasciculation GO:0007413 18 7 0,000 0,04311446 0,1000322 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04311446 0,09993583 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04311446 0,09983965 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04311446 0,09974365 ! diuresis GO:0030146 12 7 0,000 0,04311446 0,09964783 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04311446 0,0995522 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04311446 0,09945675 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04311446 0,09936149 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04311446 0,09926641 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04311446 0,09917151 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04311446 0,09907679 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04311446 0,09898225 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04311446 0,09888789 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04311446 0,09879371 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04311446 0,09869971 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04311446 0,09860589 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04311446 0,09851225 ! lymph node development GO:0048535 10 7 0,000 0,04311446 0,09841878 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04311446 0,09832549 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04311446 0,09823238 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04311446 0,09813945 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04311446 0,09804669 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04311446 0,0979541 ! adult feeding behavior GO:0008343 9 7 0,000 0,04311446 0,09786169 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04311446 0,09776946 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04311446 0,0976774 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04311446 0,09758551 ! muscle adaptation GO:0043500 14 7 0,000 0,04311446 0,09749379 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04311446 0,09740225 ! retina homeostasis GO:0001895 12 7 0,000 0,04311446 0,09731088 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04311446 0,09721968 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04311446 0,09712865 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04311446 0,09703779 ! protein prenylation GO:0018342 18 7 0,000 0,04311446 0,0969471 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04311446 0,09685658 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04311446 0,09676623 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04311446 0,09667604 ! cell maturation GO:0048469 100 53 1,000 0,04380629 0,09813588 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,0453077 0,10140495 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,0453077 0,10131071 ! cell recognition GO:0008037 85 54 1,000 0,0453077 0,10121664 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,0453077 0,10112275 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,04682792 0,10441888 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04682792 0,10432219 ! aging GO:0007568 103 55 1,000 0,04682792 0,10422569 ! heart morphogenesis GO:0003007 97 55 1,000 0,04682792 0,10412936 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04682792 0,10403321 ! nuclear export GO:0051168 97 55 1,000 0,04682792 0,10393724 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,04682792 0,10384144 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04682792 0,10374583 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04836666 0,10705628 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04836666 0,10695788 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04912082 0,10852588 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04912082 0,10842632 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04912082 0,10832694 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04912082 0,10822773 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04912082 0,10812872 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04912082 0,10802988 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04912082 0,10793122 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04912082 0,10783274 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04912082 0,10773445 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04912082 0,10763633 ! oligopeptide transport GO:0006857 15 8 0,000 0,04912082 0,10753839 ! UTP metabolic process GO:0046051 8 8 0,000 0,04912082 0,10744062 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04912082 0,10734304 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04912082 0,10724563 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04912082 0,1071484 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04912082 0,10705135 ! succinate metabolic process GO:0006105 14 8 0,000 0,04912082 0,10695447 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04912082 0,10685776 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04912082 0,10676123 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04912082 0,10666488 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04912082 0,1065687 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04912082 0,10647269 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04912082 0,10637686 ! reflex GO:0060004 16 8 0,000 0,04912082 0,10628119 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04912082 0,1061857 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04912082 0,10609038 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04912082 0,10599523 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04912082 0,10590026 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04912082 0,10580545 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04912082 0,10571081 ! pigment granule organization GO:0048753 16 8 0,000 0,04912082 0,10561634 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04912082 0,10552204 ! histidine metabolic process GO:0006547 16 8 0,000 0,04912082 0,10542791 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04912082 0,10533395 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04912082 0,10524015 ! glycine catabolic process GO:0006546 13 8 0,000 0,04912082 0,10514652 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04912082 0,10505305 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04912082 0,10495976 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04912082 0,10486663 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04912082 0,10477366 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04912082 0,10468086 ! macrophage activation GO:0042116 12 8 0,000 0,04912082 0,10458822 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04912082 0,10449574 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04912082 0,10440343 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04912082 0,10431129 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04912082 0,1042193 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04912082 0,10412748 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04912082 0,10403582 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04912082 0,10394432 ! osteoblast development GO:0002076 16 8 0,000 0,04912082 0,10385298 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04912082 0,1037618 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04912082 0,10367078 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04912082 0,10357992 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04912082 0,10348922 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04912082 0,10339868 ! response to UV-B GO:0010224 16 8 0,000 0,04912082 0,10330829 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04912082 0,10321807 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04912082 0,103128 ! intermediate filament organization GO:0045109 12 8 0,000 0,04912082 0,10303809 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04912082 0,10294833 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04912082 0,10285873 ! cellular extravasation GO:0045123 12 8 0,000 0,04912082 0,10276929 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04912082 0,10268001 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04912082 0,10259087 ! response to antibiotic GO:0046677 11 8 0,000 0,04912082 0,1025019 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04912082 0,10241307 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04912082 0,1023244 ! DNA topological change GO:0006265 12 8 0,000 0,04912082 0,10223589 ! response to tropane GO:0014073 15 8 0,000 0,04912082 0,10214752 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04912082 0,10205931 ! melanosome transport GO:0032402 13 8 0,000 0,04912082 0,10197126 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04912082 0,10188335 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04912082 0,1017956 ! mast cell activation GO:0045576 14 8 0,000 0,04912082 0,10170799 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04912082 0,10162054 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04912082 0,10153324 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04912082 0,10144608 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04912082 0,10135908 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04912082 0,10127222 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04912082 0,10118552 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04912082 0,10109896 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04912082 0,10101255 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04912082 0,10092629 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04912082 0,10084018 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04912082 0,10075421 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04912082 0,10066839 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04912082 0,10058271 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04912082 0,10049718 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04912082 0,1004118 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04912082 0,10032656 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04912082 0,10024146 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04912082 0,10015651 ! hormone catabolic process GO:0042447 17 8 0,000 0,04912082 0,10007171 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04912082 0,09998704 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04912082 0,09990252 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04912082 0,09981815 ! ATP catabolic process GO:0006200 11 8 0,000 0,04912082 0,09973391 ! blastocyst growth GO:0001832 19 8 0,000 0,04912082 0,09964982 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04912082 0,09956587 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04912082 0,09948206 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04912082 0,09939839 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04912082 0,09931486 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04912082 0,09923147 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04912082 0,09914823 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04912082 0,09906512 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04912082 0,09898215 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04912082 0,09889932 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04912082 0,09881663 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04912082 0,09873407 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04912082 0,09865166 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04912082 0,09856938 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04912082 0,09848724 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04912082 0,09840523 ! lipid modification GO:0030258 97 57 1,000 0,04992363 0,09993032 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04992363 0,09984725 ! muscle fiber development GO:0048747 112 57 1,000 0,04992363 0,09976432 ! maintenance of location GO:0051235 118 57 1,000 0,04992363 0,09968153 ! adult behavior GO:0030534 99 58 1,000 0,05149854 0,10274087 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,05149854 0,10265575 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,05309111 0,10574273 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05470107 0,1088592 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,05470107 0,10876923 ! regulation of heart contraction GO:0008016 110 60 1,000 0,05470107 0,10867941 ! camera-type eye development GO:0043010 116 60 1,000 0,05470107 0,10858974 ! axon extension GO:0048675 15 9 0,000 0,05508967 0,10927102 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05508967 0,10918101 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05508967 0,10909115 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05508967 0,10900143 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05508967 0,10891187 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05508967 0,10882245 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05508967 0,10873318 ! phosphate transport GO:0006817 19 9 0,000 0,05508967 0,10864405 ! reproductive behavior GO:0019098 19 9 0,000 0,05508967 0,10855507 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05508967 0,10846624 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05508967 0,10837755 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05508967 0,10828901 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05508967 0,10820061 ! GTP metabolic process GO:0046039 9 9 0,000 0,05508967 0,10811235 ! RNA methylation GO:0001510 15 9 0,000 0,05508967 0,10802424 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05508967 0,10793627 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05508967 0,10784845 ! regulation of histone modification GO:0031056 12 9 0,000 0,05508967 0,10776077 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05508967 0,10767323 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05508967 0,10758583 ! chemosensory behavior GO:0007635 20 9 0,000 0,05508967 0,10749858 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05508967 0,10741146 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05508967 0,10732449 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05508967 0,10723766 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05508967 0,10715097 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05508967 0,10706441 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05508967 0,106978 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05508967 0,10689173 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05508967 0,1068056 ! protein targeting to ER GO:0045047 22 9 0,000 0,05508967 0,1067196 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05508967 0,10663374 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05508967 0,10654803 ! T cell selection GO:0045058 23 9 0,000 0,05508967 0,10646245 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05508967 0,106377 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05508967 0,1062917 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05508967 0,10620653 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05508967 0,10612149 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05508967 0,1060366 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05508967 0,10595183 ! mannose metabolic process GO:0006013 13 9 0,000 0,05508967 0,10586721 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05508967 0,10578272 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05508967 0,10569836 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05508967 0,10561414 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05508967 0,10553005 ! ruffle organization GO:0031529 15 9 0,000 0,05508967 0,1054461 ! retinol metabolic process GO:0042572 18 9 0,000 0,05508967 0,10536228 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05508967 0,10527859 ! behavioral fear response GO:0001662 22 9 0,000 0,05508967 0,10519504 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05508967 0,10511161 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05508967 0,10502832 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05508967 0,10494517 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05508967 0,10486214 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05508967 0,10477924 ! segment specification GO:0007379 13 9 0,000 0,05508967 0,10469648 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05508967 0,10461385 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05508967 0,10453134 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05508967 0,10444897 ! response to amine stimulus GO:0014075 13 9 0,000 0,05508967 0,10436673 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05508967 0,10428461 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05508967 0,10420263 ! erythrocyte development GO:0048821 15 9 0,000 0,05508967 0,10412077 ! gas homeostasis GO:0033483 16 9 0,000 0,05508967 0,10403905 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05508967 0,10395745 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05508967 0,10387598 ! renal water homeostasis GO:0003091 14 9 0,000 0,05508967 0,10379463 ! postreplication repair GO:0006301 22 9 0,000 0,05508967 0,10371342 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05508967 0,10363233 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05508967 0,10355136 ! icosanoid secretion GO:0032309 15 9 0,000 0,05508967 0,10347053 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05508967 0,10338982 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05508967 0,10330923 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05508967 0,10322877 ! regulation of cell division GO:0051302 15 9 0,000 0,05508967 0,10314844 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05508967 0,10306823 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05508967 0,10298815 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05508967 0,10290819 ! sterol catabolic process GO:0016127 11 9 0,000 0,05508967 0,10282835 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05508967 0,10274864 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05508967 0,10266905 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05508967 0,10258959 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05508967 0,10251024 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05508967 0,10243102 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05508967 0,10235193 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05508967 0,10227295 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05508967 0,1021941 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05508967 0,10211537 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05508967 0,10203675 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05508967 0,10195826 ! pigment granule transport GO:0051904 17 9 0,000 0,05508967 0,1018799 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05508967 0,10180165 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05508967 0,10172352 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05508967 0,10164551 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05508967 0,10156762 ! mitochondrion localization GO:0051646 15 9 0,000 0,05508967 0,10148985 ! ear development GO:0043583 103 62 1,000 0,05797201 0,10671817 ! regulation of mitosis GO:0007088 105 63 1,000 0,05963244 0,10969086 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,05963244 0,10960707 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,05963244 0,1095234 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06102125 0,11198866 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06102125 0,1119033 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06102125 0,11181807 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06102125 0,11173298 ! synapsis GO:0007129 13 10 0,000 0,06102125 0,11164801 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06102125 0,11156317 ! N-glycan processing GO:0006491 20 10 0,000 0,06102125 0,11147846 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06102125 0,11139388 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06102125 0,11130942 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06102125 0,1112251 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06102125 0,1111409 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06102125 0,11105683 ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06102125 0,11097289 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06102125 0,11088907 ! androgen metabolic process GO:0008209 17 10 0,000 0,06102125 0,11080538 ! phospholipid efflux GO:0033700 16 10 0,000 0,06102125 0,11072182 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06102125 0,11063838 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06102125 0,11055507 ! pathogenesis GO:0009405 13 10 0,000 0,06102125 0,11047188 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06102125 0,11038882 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06102125 0,11030588 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06102125 0,11022307 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06102125 0,11014038 ! endoderm development GO:0007492 16 10 0,000 0,06102125 0,11005782 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06102125 0,10997538 ! arginine catabolic process GO:0006527 13 10 0,000 0,06102125 0,10989306 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06102125 0,10981087 ! proline metabolic process GO:0006560 13 10 0,000 0,06102125 0,1097288 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06102125 0,10964685 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06102125 0,10956502 ! V(D)J recombination GO:0033151 28 10 0,000 0,06102125 0,10948332 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06102125 0,10940174 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06102125 0,10932027 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06102125 0,10923894 ! B cell proliferation GO:0042100 18 10 0,000 0,06102125 0,10915772 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06102125 0,10907662 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06102125 0,10899564 ! multicellular organism growth GO:0035264 18 10 0,000 0,06102125 0,10891478 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06102125 0,10883405 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06102125 0,10875343 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06102125 0,10867293 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06102125 0,10859255 ! macroautophagy GO:0016236 17 10 0,000 0,06102125 0,10851229 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06102125 0,10843215 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06102125 0,10835212 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06102125 0,10827222 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06102125 0,10819243 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06102125 0,10811276 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06102125 0,10803321 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06102125 0,10795377 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06102125 0,10787445 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06102125 0,10779525 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06102125 0,10771616 ! response to dsRNA GO:0043331 20 10 0,000 0,06102125 0,10763719 ! DNA ligation GO:0006266 19 10 0,000 0,06102125 0,10755834 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06102125 0,1074796 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06102125 0,10740097 ! melanosome localization GO:0032400 16 10 0,000 0,06102125 0,10732246 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06102125 0,10724407 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06102125 0,10716579 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06102125 0,10708762 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06102125 0,10700957 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06102125 0,10693163 ! mRNA cleavage GO:0006379 17 10 0,000 0,06102125 0,10685381 ! protein sumoylation GO:0016925 15 10 0,000 0,06102125 0,10677609 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06102125 0,1066985 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06102125 0,10662101 ! salivary gland development GO:0007431 27 10 0,000 0,06102125 0,10654364 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06102125 0,10646637 ! apical protein localization GO:0045176 15 10 0,000 0,06102125 0,10638922 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06102125 0,10631219 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06102125 0,10623526 ! midbrain development GO:0030901 13 10 0,000 0,06102125 0,10615844 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06102125 0,10608174 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06102125 0,10600515 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06102125 0,10592866 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06102125 0,10585229 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06102125 0,10577603 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06102125 0,10569988 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06102125 0,10562383 ! detection of calcium ion GO:0005513 23 10 0,000 0,06102125 0,1055479 ! oocyte development GO:0048599 17 10 0,000 0,06102125 0,10547208 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06102125 0,10539636 ! blastocyst formation GO:0001825 17 10 0,000 0,06102125 0,10532075 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06102125 0,10524525 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06102125 0,10516986 ! activation of innate immune response GO:0002218 12 10 0,000 0,06102125 0,10509458 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06102125 0,10501941 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06102125 0,10494434 ! response to nicotine GO:0035094 20 10 0,000 0,06102125 0,10486938 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06102125 0,10479452 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06102125 0,10471978 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,06300189 0,10804173 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,06471038 0,11089257 ! actin filament organization GO:0007015 148 66 1,000 0,06471038 0,11081364 ! extracellular matrix organization GO:0030198 133 66 1,000 0,06471038 0,11073482 ! secondary metabolic process GO:0019748 116 66 1,000 0,06471038 0,11065612 ! developmental maturation GO:0021700 116 66 1,000 0,06471038 0,11057753 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06643435 0,1134429 ! chromosome segregation GO:0007059 113 67 1,000 0,06643435 0,11336244 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,06643435 0,1132821 ! adaptive immune response GO:0002250 119 67 1,000 0,06643435 0,11320187 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! respiratory burst GO:0045730 17 11 0,000 0,06691579 0,11394154 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06691579 0,11386096 ! neuron fate specification GO:0048665 17 11 0,000 0,06691579 0,11378049 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06691579 0,11370014 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06691579 0,1136199 ! thyroid gland development GO:0030878 26 11 0,000 0,06691579 0,11353977 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06691579 0,11345976 ! response to pain GO:0048265 24 11 0,000 0,06691579 0,11337986 ! T cell proliferation GO:0042098 26 11 0,000 0,06691579 0,11330007 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06691579 0,11322039 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,06691579 0,11314083 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06691579 0,11306137 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06691579 0,11298203 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06691579 0,1129028 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06691579 0,11282368 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06691579 0,11274468 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06691579 0,11266578 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06691579 0,11258699 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06691579 0,11250831 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! lipid digestion GO:0044241 18 11 0,000 0,06691579 0,11242975 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06691579 0,11235129 ! UV protection GO:0009650 19 11 0,000 0,06691579 0,11227294 ! adult heart development GO:0007512 14 11 0,000 0,06691579 0,1121947 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06691579 0,11211657 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06691579 0,11203855 ! temperature homeostasis GO:0001659 17 11 0,000 0,06691579 0,11196064 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06691579 0,11188283 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06691579 0,11180514 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06691579 0,11172755 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06691579 0,11165007 ! regulation of organ growth GO:0046620 13 11 0,000 0,06691579 0,11157269 ! pigment granule localization GO:0051875 20 11 0,000 0,06691579 0,11149543 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06691579 0,11141827 ! vasoconstriction GO:0042310 18 11 0,000 0,06691579 0,11134122 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06691579 0,11126427 ! embryonic axis specification GO:0000578 18 11 0,000 0,06691579 0,11118743 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06691579 0,1111107 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06691579 0,11103407 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06691579 0,11095755 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06691579 0,11088113 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06691579 0,11080482 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06691579 0,11072861 ! zymogen activation GO:0031638 15 11 0,000 0,06691579 0,11065251 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06691579 0,11057651 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06691579 0,11050062 ! nucleosome positioning GO:0016584 15 11 0,000 0,06691579 0,11042483 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06691579 0,11034914 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06691579 0,11027356 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06691579 0,11019808 ! acid secretion GO:0046717 18 11 0,000 0,06691579 0,11012271 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06691579 0,11004744 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06691579 0,10997227 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06691579 0,1098972 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06691579 0,10982224 ! oocyte differentiation GO:0009994 18 11 0,000 0,06691579 0,10974737 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06691579 0,10967261 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06691579 0,10959796 ! cholesterol efflux GO:0033344 19 11 0,000 0,06691579 0,1095234 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06691579 0,10944894 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06691579 0,10937459 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06691579 0,10930034 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06691579 0,10922619 ! embryonic gut development GO:0048566 15 11 0,000 0,06691579 0,10915213 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06691579 0,10907818 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06691579 0,10900433 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06691579 0,10893058 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06691579 0,10885693 ! defense response to fungus GO:0050832 13 11 0,000 0,06691579 0,10878338 ! developmental induction GO:0031128 19 11 0,000 0,06691579 0,10870992 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06691579 0,10863657 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06691579 0,10856332 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06691579 0,10849016 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06691579 0,1084171 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06691579 0,10834414 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06691579 0,10827128 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06817355 0,11023224 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,06817355 0,11015821 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06992773 0,11291686 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06992773 0,11284113 ! appendage morphogenesis GO:0035107 135 70 1,000 0,07169663 0,11561802 GO:0035108|limb morphogenesis, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07277353 0,11727602 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07277353 0,11719753 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07277353 0,11711913 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07277353 0,11704084 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07277353 0,11696266 ! mating GO:0007618 17 12 0,000 0,07277353 0,11688458 ! protein complex disassembly GO:0043241 27 12 0,000 0,07277353 0,11680661 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,07277353 0,11672874 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07277353 0,11665097 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07277353 0,1165733 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07277353 0,11649574 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07277353 0,11641829 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07277353 0,11634093 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07277353 0,11626368 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07277353 0,11618653 ! drug transport GO:0015893 16 12 0,000 0,07277353 0,11610949 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07277353 0,11603254 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07277353 0,1159557 ! focal adhesion formation GO:0048041 35 12 0,000 0,07277353 0,11587896 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07277353 0,11580232 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07277353 0,11572578 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07277353 0,11564934 GO:0006509|membrane protein ectodomain proteolysis, ! fear response GO:0042596 26 12 0,000 0,07277353 0,11557301 ! monoamine transport GO:0015844 18 12 0,000 0,07277353 0,11549677 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07277353 0,11542064 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07277353 0,1153446 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07277353 0,11526867 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07277353 0,11519283 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07277353 0,1151171 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07277353 0,11504146 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07277353 0,11496593 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07277353 0,11489049 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07277353 0,11481515 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07277353 0,11473991 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07277353 0,11466477 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07277353 0,11458973 ! fucose catabolic process GO:0019317 22 12 0,000 0,07277353 0,11451478 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07277353 0,11443994 ! histone methylation GO:0016571 26 12 0,000 0,07277353 0,11436519 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07277353 0,11429054 ! gland morphogenesis GO:0022612 29 12 0,000 0,07277353 0,11421598 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07277353 0,11414153 ! T cell homeostasis GO:0043029 25 12 0,000 0,07277353 0,11406717 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07277353 0,11399291 ! spleen development GO:0048536 22 12 0,000 0,07277353 0,11391874 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07277353 0,11384467 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07277353 0,1137707 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07277353 0,11369682 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07277353 0,11362304 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07277353 0,11354935 ! response to cold GO:0009409 17 12 0,000 0,07277353 0,11347576 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07277353 0,11340227 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07277353 0,11332887 ! amine catabolic process GO:0009310 117 71 1,000 0,07347999 0,11435502 ! appendage development GO:0048736 136 71 1,000 0,07347999 0,1142811 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 1,000 0,07347999 0,11420727 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07347999 0,11413354 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,07527757 0,11685022 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,07527757 0,11677488 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,07527757 0,11669964 ! axon guidance GO:0007411 139 73 1,000 0,07708913 0,11943107 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07859468 0,1216852 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07859468 0,12160694 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07859468 0,12152879 ! peroxisomal transport GO:0043574 24 13 0,000 0,07859468 0,12145074 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07859468 0,12137278 ! lipid localization GO:0010876 28 13 0,000 0,07859468 0,12129493 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,07859468 0,12121718 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07859468 0,12113952 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07859468 0,12106197 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07859468 0,12098452 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07859468 0,12090716 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07859468 0,1208299 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07859468 0,12075274 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07859468 0,12067568 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07859468 0,12059872 ! methionine metabolic process GO:0006555 27 13 0,000 0,07859468 0,12052186 ! plasma membrane organization GO:0007009 24 13 0,000 0,07859468 0,12044509 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07859468 0,12036843 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07859468 0,12029186 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07859468 0,12021538 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07859468 0,12013901 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07859468 0,12006273 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07859468 0,11998655 ! exocrine system development GO:0035272 32 13 0,000 0,07859468 0,11991046 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07859468 0,11983447 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07859468 0,11975858 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07859468 0,11968278 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07859468 0,11960708 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07859468 0,11953148 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07859468 0,11945597 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07859468 0,11938055 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07859468 0,11930523 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07859468 0,11923001 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07859468 0,11915488 ! ribosome assembly GO:0042255 17 13 0,000 0,07859468 0,11907985 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07859468 0,11900491 ! chromatin silencing GO:0006342 26 13 0,000 0,07859468 0,11893006 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07859468 0,11885531 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07859468 0,11878065 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07859468 0,11870609 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07859468 0,11863162 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07859468 0,11855724 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07859468 0,11848296 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07859468 0,11840876 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07859468 0,11833467 ! embryonic placenta development GO:0001892 23 13 0,000 0,07859468 0,11826066 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07859468 0,11818675 ! insulin secretion GO:0030073 23 13 0,000 0,07859468 0,11811293 ! actin filament polymerization GO:0030041 24 13 0,000 0,07859468 0,1180392 ! acrosome reaction GO:0007340 18 13 0,000 0,07859468 0,11796556 ! neurotransmitter transport GO:0006836 123 74 1,000 0,07891441 0,11837162 ! exocytosis GO:0006887 133 74 1,000 0,07891441 0,11829787 ! eye development GO:0001654 143 74 1,000 0,07891441 0,11822421 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,08075318 0,12090365 ! rhythmic process GO:0048511 128 75 1,000 0,08075318 0,12082846 ! rRNA transcription GO:0009303 25 14 0,000 0,08437948 0,1261759 ! lactation GO:0007595 26 14 0,000 0,08437948 0,12609753 ! reproductive cellular process GO:0048610 20 14 0,000 0,08437948 0,12601926 ! tRNA modification GO:0006400 20 14 0,000 0,08437948 0,12594108 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08437948 0,125863 ! regulation of S phase GO:0033261 23 14 0,000 0,08437948 0,12578502 ! water transport GO:0006833 21 14 0,000 0,08437948 0,12570714 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08437948 0,12562935 ! non-recombinational repair GO:0000726 25 14 0,000 0,08437948 0,12555165 GO:0006303|double-strand break repair via nonhomologous end joining, ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08437948 0,12547406 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08437948 0,12539656 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08437948 0,12531915 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08437948 0,12524184 ! palate development GO:0060021 31 14 0,000 0,08437948 0,12516463 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08437948 0,12508751 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08437948 0,12501048 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08437948 0,12493355 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08437948 0,12485672 ! arginine metabolic process GO:0006525 17 14 0,000 0,08437948 0,12477998 ! regulation of heart rate GO:0002027 24 14 0,000 0,08437948 0,12470333 ! organic alcohol transport GO:0015850 29 14 0,000 0,08437948 0,12462678 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08437948 0,12455032 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,08437948 0,12447396 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08437948 0,12439769 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08437948 0,12432151 ! L-amino acid transport GO:0015807 30 14 0,000 0,08437948 0,12424543 ! bone mineralization GO:0030282 17 14 0,000 0,08437948 0,12416943 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08437948 0,12409354 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08437948 0,12401773 ! cerebellum development GO:0021549 21 14 0,000 0,08437948 0,12394202 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08437948 0,1238664 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08437948 0,12379087 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08437948 0,12371543 ! cofactor transport GO:0051181 26 14 0,000 0,08437948 0,12364009 ! NADP metabolic process GO:0006739 24 14 0,000 0,08437948 0,12356484 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08437948 0,12348967 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08437948 0,1234146 ! intestinal absorption GO:0050892 25 14 0,000 0,08437948 0,12333963 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08437948 0,12326474 ! oxygen transport GO:0015671 21 14 0,000 0,08437948 0,12318994 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08437948 0,12311524 ! male genitalia development GO:0030539 24 14 0,000 0,08437948 0,12304062 ! regulation of axon extension GO:0030516 37 14 0,000 0,08437948 0,1229661 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08437948 0,12289166 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,08447023 0,12294941 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,08447023 0,12287508 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,08634804 0,12553075 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,08634804 0,12545494 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,08823839 0,12812407 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,08823839 0,12804679 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09012815 0,13071027 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09012815 0,13063152 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,09012815 0,13055288 ! superoxide anion generation GO:0042554 20 15 0,000 0,09012815 0,13047433 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,09012815 0,13039587 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,09012815 0,13031751 ! copper ion transport GO:0006825 20 15 0,000 0,09012815 0,13023924 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,09012815 0,13016106 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,09012815 0,13008298 ! sulfate transport GO:0008272 23 15 0,000 0,09012815 0,13000499 ! response to cAMP GO:0051591 22 15 0,000 0,09012815 0,1299271 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,09012815 0,1298493 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,09012815 0,12977159 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,09012815 0,12969398 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,09012815 0,12961646 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,09012815 0,12953903 ! response to hexose stimulus GO:0009746 22 15 0,000 0,09012815 0,12946169 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,09012815 0,12938445 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,09012815 0,12930729 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,09012815 0,12923023 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,09012815 0,12915326 ! regulation of exocytosis GO:0017157 22 15 0,000 0,09012815 0,12907639 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,09012815 0,1289996 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,09012815 0,12892291 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,09012815 0,1288463 ! regulation of vasodilation GO:0042312 26 15 0,000 0,09012815 0,12876979 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,09012815 0,12869337 ! mRNA splice site selection GO:0006376 38 15 0,000 0,09012815 0,12861704 ! tissue regeneration GO:0042246 26 15 0,000 0,09012815 0,1285408 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,09012815 0,12846465 ! water homeostasis GO:0030104 27 15 0,000 0,09012815 0,12838859 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09012815 0,12831262 ! muscle maintenance GO:0046716 26 15 0,000 0,09012815 0,12823674 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,09012815 0,12816095 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,09012815 0,12808525 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,09012815 0,12800964 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09012815 0,12793412 ! heme biosynthetic process GO:0006783 29 15 0,000 0,09012815 0,12785869 ! cell killing GO:0001906 29 15 0,000 0,09012815 0,12778334 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,09012815 0,12770809 ! detection of bacterium GO:0016045 18 15 0,000 0,09012815 0,12763292 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,09012815 0,12755784 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,09012815 0,12748285 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,09012815 0,12740795 ! peptide hormone processing GO:0016486 23 15 0,000 0,09012815 0,12733314 ! muscle cell differentiation GO:0042692 159 80 1,000 0,09014106 0,12727664 ! protein import into nucleus GO:0006606 158 80 1,000 0,09014106 0,12720199 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,09205582 0,12982785 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,09205582 0,12975179 ! nuclear import GO:0051170 161 81 1,000 0,09205582 0,12967582 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,09205582 0,12959994 ! response to drug GO:0042493 143 82 1,000 0,09398244 0,13223495 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09584092 0,13477104 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09584092 0,13469232 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09584092 0,13461369 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09584092 0,13453515 ! bone remodeling GO:0046849 27 16 0,000 0,09584092 0,13445671 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09584092 0,13437835 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09584092 0,13430009 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09584092 0,13422192 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09584092 0,13414384 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09584092 0,13406584 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09584092 0,13398794 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09584092 0,13391014 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09584092 0,13383242 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09584092 0,13375479 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09584092 0,13367725 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09584092 0,1335998 ! response to osmotic stress GO:0006970 25 16 0,000 0,09584092 0,13352244 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09584092 0,13344517 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09584092 0,13336799 ! fructose metabolic process GO:0006000 25 16 0,000 0,09584092 0,1332909 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09584092 0,1332139 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09584092 0,13313698 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09584092 0,13306016 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09584092 0,13298342 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09584092 0,13290677 ! axon cargo transport GO:0008088 43 16 0,000 0,09584092 0,13283021 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09584092 0,13275374 ! DNA replication initiation GO:0006270 27 16 0,000 0,09584092 0,13267736 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09584092 0,13260107 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09584092 0,13252486 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09584092 0,13244874 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09584092 0,13237271 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09584092 0,13229676 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09584092 0,1322209 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09584092 0,13214513 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09584092 0,13206945 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09584092 0,13199385 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09584092 0,13191834 ! defense response to virus GO:0051607 37 16 0,000 0,09584092 0,13184291 ! regulation of ligase activity GO:0051340 142 84 1,000 0,0978704 0,13455781 ! response to unfolded protein GO:0006986 131 85 1,000 0,09983129 0,13717537 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09983129 0,13709707 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10151801 0,1393339 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10151801 0,13925446 ! metencephalon development GO:0022037 30 17 0,000 0,10151801 0,13917512 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10151801 0,13909586 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10151801 0,13901669 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10151801 0,13893762 ! endothelial cell migration GO:0043542 28 17 0,000 0,10151801 0,13885863 ! inositol metabolic process GO:0006020 28 17 0,000 0,10151801 0,13877973 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10151801 0,13870093 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10151801 0,13862221 ! adult walking behavior GO:0007628 33 17 0,000 0,10151801 0,13854358 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10151801 0,13846504 ! heart looping GO:0001947 30 17 0,000 0,10151801 0,13838659 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10151801 0,13830823 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,10151801 0,13822995 ! myoblast differentiation GO:0045445 45 17 0,000 0,10151801 0,13815177 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10151801 0,13807367 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10151801 0,13799567 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10151801 0,13791775 ! glycine metabolic process GO:0006544 28 17 0,000 0,10151801 0,13783992 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10151801 0,13776217 ! NAD metabolic process GO:0019674 29 17 0,000 0,10151801 0,13768452 ! DNA integration GO:0015074 29 17 0,000 0,10151801 0,13760695 ! regulation of protein binding GO:0043393 33 17 0,000 0,10151801 0,13752947 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10151801 0,13745207 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10151801 0,13737476 ! genitalia development GO:0048806 30 17 0,000 0,10151801 0,13729754 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10151801 0,13722041 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10151801 0,13714336 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,10151801 0,1370664 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10151801 0,13698953 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10151801 0,13691274 ! steroid catabolic process GO:0006706 31 17 0,000 0,10151801 0,13683604 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10151801 0,13675942 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10151801 0,13668289 ! gas transport GO:0015669 25 17 0,000 0,10151801 0,13660645 ! organic cation transport GO:0015695 31 17 0,000 0,10151801 0,13653009 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10151801 0,13645382 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,10151801 0,13637763 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10151801 0,13630152 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,10151801 0,1362255 ! amine biosynthetic process GO:0009309 138 86 1,000 0,10180317 0,136532 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,10378582 0,13911347 ! protein localization in nucleus GO:0034504 176 87 1,000 0,10378582 0,13903602 ! regulation of neurological system process GO:0031644 148 88 1,000 0,10577904 0,14162736 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10715964 0,14339605 ! neuron maturation GO:0042551 42 18 0,000 0,10715964 0,14331634 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10715964 0,14323672 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10715964 0,14315719 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10715964 0,14307774 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10715964 0,14299839 ! memory GO:0007613 31 18 0,000 0,10715964 0,14291912 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10715964 0,14283994 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10715964 0,14276085 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10715964 0,14268185 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10715964 0,14260293 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10715964 0,1425241 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,10715964 0,14244536 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10715964 0,1423667 ! response to retinoic acid GO:0032526 26 18 0,000 0,10715964 0,14228813 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,10715964 0,14220965 ! response to fungus GO:0009620 21 18 0,000 0,10715964 0,14213125 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10715964 0,14205294 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10715964 0,14197472 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10715964 0,14189658 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10715964 0,14181853 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10715964 0,14174057 ! vitamin transport GO:0051180 27 18 0,000 0,10715964 0,14166269 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10715964 0,1415849 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10715964 0,14150719 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10715964 0,14142956 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10715964 0,14135203 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10715964 0,14127457 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,10979634 0,14467141 ! sex differentiation GO:0007548 145 90 1,000 0,10979634 0,14459222 ! response to protein stimulus GO:0051789 149 91 1,000 0,11182001 0,14717666 ! protein secretion GO:0009306 39 19 0,000 0,11276603 0,14834067 ! positive regulation of translation GO:0045727 30 19 0,000 0,11276603 0,1482596 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11276603 0,14817863 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,11276603 0,14809775 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11276603 0,14801695 ! skin development GO:0043588 36 19 0,000 0,11276603 0,14793625 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,11276603 0,14785563 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11276603 0,1477751 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,11276603 0,14769465 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11276603 0,1476143 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11276603 0,14753403 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,11276603 0,14745385 ! response to vitamin A GO:0033189 27 19 0,000 0,11276603 0,14737375 ! heme metabolic process GO:0042168 36 19 0,000 0,11276603 0,14729374 ! actin filament bundle formation GO:0051017 42 19 0,000 0,11276603 0,14721382 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,11276603 0,14713399 ! plasma membrane fusion GO:0045026 28 19 0,000 0,11276603 0,14705424 ! peptide cross-linking GO:0018149 37 19 0,000 0,11276603 0,14697458 ! heart process GO:0003015 30 19 0,000 0,11276603 0,14689501 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11276603 0,14681552 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11276603 0,14673611 ! cellular pigmentation GO:0033059 36 19 0,000 0,11276603 0,1466568 ! G1 phase GO:0051318 40 19 0,000 0,11276603 0,14657757 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,11276603 0,14649842 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11276603 0,14641936 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,11276603 0,14634039 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11276603 0,1462615 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11276603 0,14618269 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,11276603 0,14610397 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,11276603 0,14602534 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,11276603 0,14594679 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,11276603 0,14586832 ! cilium assembly GO:0042384 37 19 0,000 0,11276603 0,14578994 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11276603 0,14571164 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,11589637 0,14967615 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,11589637 0,14959585 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,11794866 0,15216326 ! regulation of T cell activation GO:0050863 158 94 1,000 0,11794866 0,15208172 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11833741 0,15250123 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11833741 0,15241959 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11833741 0,15233804 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11833741 0,15225658 ! response to vitamin GO:0033273 31 20 0,000 0,11833741 0,1521752 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11833741 0,15209391 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11833741 0,15201271 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11833741 0,15193159 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11833741 0,15185056 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11833741 0,15176962 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11833741 0,15168876 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11833741 0,15160799 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11833741 0,1515273 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11833741 0,1514467 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11833741 0,15136619 ! body fluid secretion GO:0007589 31 20 0,000 0,11833741 0,15128576 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11833741 0,15120542 ! peptide secretion GO:0002790 35 20 0,000 0,11833741 0,15112516 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11833741 0,15104499 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11833741 0,1509649 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11833741 0,1508849 ! sensory perception of pain GO:0019233 30 20 0,000 0,11833741 0,15080498 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11833741 0,15072515 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11833741 0,1506454 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11833741 0,15056573 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11833741 0,15048615 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11833741 0,15040666 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11833741 0,15032725 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11833741 0,15024792 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11833741 0,15016867 ! regulation of glucose import GO:0046324 29 20 0,000 0,11833741 0,15008951 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11833741 0,15001043 ! actin filament-based movement GO:0030048 43 20 0,000 0,11833741 0,14993144 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11833741 0,14985253 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11833741 0,1497737 ! negative regulation of translation GO:0017148 29 20 0,000 0,11833741 0,14969495 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11833741 0,14961629 ! detection of stimulus GO:0051606 151 96 1,000 0,1220805 0,15426769 ! regulation of cell killing GO:0031341 42 21 0,000 0,12387398 0,15645186 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12387398 0,15636978 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12387398 0,15628778 ! hormone secretion GO:0046879 38 21 0,000 0,12387398 0,15620587 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12387398 0,15612404 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12387398 0,1560423 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12387398 0,15596065 ! axis specification GO:0009798 38 21 0,000 0,12387398 0,15587908 ! ovarian follicle development GO:0001541 35 21 0,000 0,12387398 0,15579759 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,12387398 0,15571619 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12387398 0,15563488 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12387398 0,15555365 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12387398 0,15547251 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12387398 0,15539145 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12387398 0,15531047 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,12387398 0,15522958 ! cytolysis GO:0019835 24 21 0,000 0,12387398 0,15514878 ! vasodilation GO:0042311 39 21 0,000 0,12387398 0,15506805 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12387398 0,15498741 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12387398 0,15490686 ! oogenesis GO:0048477 36 21 0,000 0,12387398 0,15482639 ! DNA modification GO:0006304 34 21 0,000 0,12387398 0,154746 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12387398 0,1546657 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,12387398 0,15458548 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12387398 0,15450534 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12387398 0,15442528 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,12387398 0,15434531 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,12387398 0,15426542 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12387398 0,15418562 ! collagen catabolic process GO:0030574 28 21 0,000 0,12387398 0,15410589 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12387398 0,15402625 ! gut development GO:0048565 39 21 0,000 0,12387398 0,15394669 ! hormone metabolic process GO:0042445 157 97 1,000 0,12415966 0,15422206 ! response to virus GO:0009615 160 98 1,000 0,12624739 0,15673437 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,12624739 0,15665354 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 1,000 0,1283435 0,1591724 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,1283435 0,1590904 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12937597 0,16028763 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12937597 0,16020514 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12937597 0,16012273 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12937597 0,1600404 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12937597 0,15995816 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12937597 0,159876 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12937597 0,15979393 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12937597 0,15971194 ! regeneration GO:0031099 41 22 0,000 0,12937597 0,15963004 ! keratinization GO:0031424 28 22 0,000 0,12937597 0,15954822 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12937597 0,15946649 ! sensory perception of taste GO:0050909 28 22 0,000 0,12937597 0,15938483 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12937597 0,15930326 ! vacuolar transport GO:0007034 36 22 0,000 0,12937597 0,15922178 ! lysosome organization GO:0007040 41 22 0,000 0,12937597 0,15914038 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12937597 0,15905906 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12937597 0,15897782 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12937597 0,15889667 ! fucose metabolic process GO:0006004 39 22 0,000 0,12937597 0,1588156 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12937597 0,15873461 ! ureteric bud development GO:0001657 43 22 0,000 0,12937597 0,15865371 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12937597 0,15857289 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12937597 0,15849215 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12937597 0,15841149 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12937597 0,15833091 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12937597 0,15825042 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12937597 0,15817001 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,12937597 0,15808968 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,13484359 0,16468714 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13484359 0,16460359 ! gluconeogenesis GO:0006094 33 23 0,000 0,13484359 0,16452011 ! viral genome replication GO:0019079 41 23 0,000 0,13484359 0,16443673 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13484359 0,16435343 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13484359 0,16427021 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13484359 0,16418708 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,13484359 0,16410403 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13484359 0,16402106 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,13484359 0,16393818 ! response to ethanol GO:0045471 46 23 0,000 0,13484359 0,16385539 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13484359 0,16377267 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13484359 0,16369004 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13484359 0,1636075 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13484359 0,16352503 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,13484359 0,16344265 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13484359 0,16336036 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13484359 0,16327814 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13484359 0,16319601 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13484359 0,16311396 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13484359 0,16303199 ! fatty acid transport GO:0015908 44 23 0,000 0,13484359 0,16295011 ! platelet activation GO:0030168 37 23 0,000 0,13484359 0,16286831 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13484359 0,16278659 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13484359 0,16270495 ! hormone transport GO:0009914 40 23 0,000 0,13484359 0,16262339 ! cell-cell recognition GO:0009988 25 23 0,000 0,13484359 0,16254192 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13484359 0,16246052 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13484359 0,16237921 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,13484359 0,16229798 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,13484359 0,16221683 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,14027705 0,16866895 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,14027705 0,1685847 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,14027705 0,16850054 ! vesicle docking GO:0048278 47 24 0,000 0,14027705 0,16841645 ! vacuole organization GO:0007033 43 24 0,000 0,14027705 0,16833245 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,14027705 0,16824854 ! digestive system process GO:0022600 39 24 0,000 0,14027705 0,16816471 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,14027705 0,16808096 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,14027705 0,1679973 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,14027705 0,16791372 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,14027705 0,16783022 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,14027705 0,16774681 ! membrane depolarization GO:0051899 39 24 0,000 0,14027705 0,16766347 ! pentose metabolic process GO:0019321 35 24 0,000 0,14027705 0,16758022 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,14027705 0,16749706 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,14027705 0,16741397 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,14027705 0,16733097 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,14027705 0,16724805 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,14027705 0,16716522 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,14027705 0,16708246 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,14027705 0,16699979 ! regulation of amine transport GO:0051952 40 24 0,000 0,14027705 0,1669172 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14567656 0,17325645 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14567656 0,17317085 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,14567656 0,17308534 ! phototransduction GO:0007602 33 25 0,000 0,14567656 0,17299991 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14567656 0,17291456 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,14567656 0,17282929 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14567656 0,17274411 ! chromosome condensation GO:0030261 45 25 0,000 0,14567656 0,17265902 ! neural crest cell development GO:0014032 54 25 0,000 0,14567656 0,17257401 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,14567656 0,17248908 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14567656 0,17240423 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14567656 0,17231947 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14567656 0,1722348 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14567656 0,1721502 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,14567656 0,17206569 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14567656 0,17198126 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14567656 0,17189691 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14567656 0,17181265 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14567656 0,17172847 ! telomere organization GO:0032200 43 25 0,000 0,14567656 0,17164437 GO:0000723|telomere maintenance, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,15104234 0,17787953 ! embryonic pattern specification GO:0009880 44 26 0,000 0,15104234 0,17779251 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,15104234 0,17770557 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,15104234 0,17761871 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,15104234 0,17753194 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,15104234 0,17744525 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,15104234 0,17735865 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,15104234 0,17727214 ! molting cycle process GO:0022404 50 26 0,000 0,15104234 0,1771857 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,15104234 0,17709936 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,15104234 0,17701309 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,15104234 0,17692691 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,15104234 0,17684082 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,15104234 0,17675481 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,15104234 0,17666888 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,15104234 0,17658303 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,15104234 0,17649727 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,15104234 0,17641159 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,15104234 0,176326 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,15104234 0,17624049 ! blastocyst development GO:0001824 49 26 0,000 0,15104234 0,17615506 ! leukocyte proliferation GO:0070661 52 26 0,000 0,15104234 0,17606971 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,15104234 0,17598445 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,15104234 0,17589926 ! neuron fate commitment GO:0048663 48 27 0,000 0,1563746 0,18202095 ! iron ion transport GO:0006826 59 27 0,000 0,1563746 0,18193293 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1563746 0,181845 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,1563746 0,18175715 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,1563746 0,18166938 ! fat cell differentiation GO:0045444 50 27 0,000 0,1563746 0,18158171 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1563746 0,18149411 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1563746 0,1814066 ! autophagy GO:0006914 41 27 0,000 0,1563746 0,18131918 ! male gonad development GO:0008584 44 27 0,000 0,1563746 0,18123184 ! response to toxin GO:0009636 47 27 0,000 0,1563746 0,18114458 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1563746 0,18105741 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1563746 0,18097032 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1563746 0,18088332 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1563746 0,18079639 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1563746 0,18070956 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1563746 0,1806228 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16167355 0,18665382 ! circadian rhythm GO:0007623 50 28 0,000 0,16167355 0,18656429 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16167355 0,18647486 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,16167355 0,18638551 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,16167355 0,18629624 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16167355 0,18620706 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16167355 0,18611797 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16167355 0,18602896 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16167355 0,18594003 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,16167355 0,1858512 ! synaptogenesis GO:0007416 42 28 0,000 0,16167355 0,18576244 ! lipid oxidation GO:0034440 43 28 0,000 0,16167355 0,18567377 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16167355 0,18558519 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,16167355 0,18549669 ! translational initiation GO:0006413 65 29 0,000 0,16693938 0,19144716 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,16693938 0,19135596 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16693938 0,19126483 ! catechol metabolic process GO:0009712 54 29 0,000 0,16693938 0,1911738 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,16693938 0,19108285 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16693938 0,19099199 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16693938 0,19090121 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16693938 0,19081052 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,16693938 0,19071992 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16693938 0,1906294 ! detection of light stimulus GO:0009583 38 29 0,000 0,16693938 0,19053897 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,16693938 0,19044863 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,16693938 0,19035837 ! tissue homeostasis GO:0001894 48 29 0,000 0,16693938 0,19026819 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,16693938 0,1901781 ! phenol metabolic process GO:0018958 55 30 0,000 0,17217231 0,19604666 ! zinc ion transport GO:0006829 45 30 0,000 0,17217231 0,19595392 ! membrane docking GO:0022406 61 30 0,000 0,17217231 0,19586127 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,17217231 0,19576871 ! cell junction assembly GO:0034329 78 30 0,000 0,17217231 0,19567623 ! regulation of innate immune response GO:0045088 51 30 0,000 0,17217231 0,19558385 ! acute-phase response GO:0006953 49 30 0,000 0,17217231 0,19549155 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,17217231 0,19539933 ! phospholipid transport GO:0015914 51 30 0,000 0,17217231 0,19530721 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,17217231 0,19521517 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,17217231 0,19512321 ! response to heat GO:0009408 50 30 0,000 0,17217231 0,19503135 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17737255 0,20082746 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,17737255 0,200733 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17737255 0,20063862 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17737255 0,20054434 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,17737255 0,20045014 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17737255 0,20035603 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,17737255 0,20026201 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17737255 0,20016808 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,17737255 0,20007424 ! ovulation cycle process GO:0022602 49 31 0,000 0,17737255 0,19998048 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17737255 0,19988681 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,17737255 0,19979323 ! peptide transport GO:0015833 55 31 0,000 0,17737255 0,19969974 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17737255 0,19960634 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,17737255 0,19951302 ! mesoderm formation GO:0001707 69 31 0,000 0,17737255 0,19941979 ! natural killer cell activation GO:0030101 45 31 0,000 0,17737255 0,19932665 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17737255 0,19923359 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17737255 0,19914062 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17737255 0,19904774 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,17737255 0,19895494 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,18254029 0,20465607 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,18254029 0,20456075 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,18254029 0,20446552 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,18254029 0,20437037 ! cholesterol transport GO:0030301 56 32 0,000 0,18254029 0,20427531 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,18254029 0,20418035 ! spliceosome assembly GO:0000245 67 32 0,000 0,18254029 0,20408547 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,18254029 0,20399068 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,18254029 0,20389597 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,18254029 0,20380136 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,18254029 0,20370683 ! ovulation cycle GO:0042698 51 32 0,000 0,18254029 0,20361239 ! BMP signaling pathway GO:0030509 64 32 0,000 0,18254029 0,20351804 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,18254029 0,20342377 ! post-embryonic development GO:0009791 69 33 0,000 0,18767573 0,20904991 ! protein targeting to membrane GO:0006612 68 33 0,000 0,18767573 0,20895317 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,18767573 0,20885653 ! ceramide metabolic process GO:0006672 64 33 0,000 0,18767573 0,20875997 ! formation of primary germ layer GO:0001704 72 33 0,000 0,18767573 0,2086635 ! cell fate specification GO:0001708 52 33 0,000 0,18767573 0,20856712 ! sterol transport GO:0015918 57 33 0,000 0,18767573 0,20847083 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,18767573 0,20837462 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,18767573 0,20827851 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,19277908 0,21384347 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,19277908 0,21374492 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,19277908 0,21364647 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,19277908 0,2135481 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,19277908 0,21344983 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,19277908 0,21335165 ! mismatch repair GO:0006298 46 34 0,000 0,19277908 0,21325355 ! spermatid development GO:0007286 63 34 0,000 0,19277908 0,21315555 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,19277908 0,21305764 ! placenta development GO:0001890 53 34 0,000 0,19277908 0,21295982 ! negative regulation of secretion GO:0051048 63 35 0,000 0,19785055 0,21846187 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,19785055 0,21836166 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,19785055 0,21826154 ! odontogenesis GO:0042476 66 35 0,000 0,19785055 0,21816151 ! female gonad development GO:0008585 58 35 0,000 0,19785055 0,21806157 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,19785055 0,21796173 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,19785055 0,21786197 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,19785055 0,21776231 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,20289031 0,22320717 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,20289031 0,22310516 ! cell junction organization GO:0034330 86 36 0,000 0,20289031 0,22300324 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,20289031 0,22290141 ! positive regulation of cell development GO:0010720 80 36 0,000 0,20289031 0,22279968 ! regulation of proteolysis GO:0030162 72 36 0,000 0,20289031 0,22269803 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,20289031 0,22259648 ! aerobic respiration GO:0009060 55 36 0,000 0,20289031 0,22249503 ! embryonic organ development GO:0048568 57 36 0,000 0,20289031 0,22239366 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,20289031 0,22229239 ! organic anion transport GO:0015711 68 37 0,000 0,20789858 0,22767591 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,20789858 0,22757233 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,20789858 0,22746884 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,20789858 0,22736545 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,20789858 0,22726215 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,21287555 0,23259699 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,21287555 0,23249141 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,21287555 0,23238592 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,21287555 0,23228053 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,21287555 0,23217523 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,21287555 0,23207004 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,21287555 0,23196493 ! mRNA catabolic process GO:0006402 71 39 0,000 0,21782141 0,23724686 ! organic ether metabolic process GO:0018904 55 39 0,000 0,21782141 0,23713951 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,21782141 0,23703225 ! ion transmembrane transport GO:0034220 66 39 0,000 0,21782141 0,23692509 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,21782141 0,23681803 ! RNA modification GO:0009451 57 39 0,000 0,21782141 0,23671107 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,21782141 0,2366042 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,22273635 0,24183378 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,22273635 0,2417247 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,22273635 0,24161572 ! feeding behavior GO:0007631 59 40 0,000 0,22273635 0,24150684 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,22273635 0,24139805 ! mesenchymal cell development GO:0014031 87 40 0,000 0,22273635 0,24128936 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,22762058 0,24646945 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,22762058 0,24635857 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,22762058 0,2462478 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,22762058 0,24613713 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,22762058 0,24602656 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,22762058 0,24591608 ! female gamete generation GO:0007292 61 41 0,000 0,22762058 0,24580571 ! polyol metabolic process GO:0019751 66 41 0,000 0,22762058 0,24569543 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,23247427 0,25082202 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,23247427 0,25070959 ! regulation of tube size GO:0035150 71 42 0,000 0,23247427 0,25059727 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,23247427 0,25048504 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,23247427 0,25037292 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,23247427 0,2502609 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,23247427 0,25014897 ! regulation of protein secretion GO:0050708 71 42 0,000 0,23247427 0,25003715 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,23247427 0,24992542 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,23729763 0,25499691 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,23729763 0,25488308 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,23729763 0,25476934 ! glucose transport GO:0015758 65 43 0,000 0,23729763 0,2546557 ! striated muscle contraction GO:0006941 77 43 0,000 0,23729763 0,25454217 ! phagocytosis GO:0006909 90 43 0,000 0,23729763 0,25442874 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,23729763 0,25431541 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,24209083 0,25933684 ! hexose transport GO:0008645 67 44 0,000 0,24209083 0,25922142 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,24209083 0,25910611 ! male sex differentiation GO:0046661 76 44 0,000 0,24209083 0,2589909 ! biopolymer methylation GO:0043414 84 44 0,000 0,24209083 0,25887579 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,24209083 0,25876079 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,24209083 0,25864588 ! developmental growth GO:0048589 82 44 0,000 0,24209083 0,25853108 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,24685407 0,26350083 ! glycolysis GO:0006096 65 45 0,000 0,24685407 0,26338398 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,24685407 0,26326723 ! leukocyte migration GO:0050900 68 45 0,000 0,24685407 0,26315059 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,24685407 0,26303405 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,24685407 0,26291761 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,24685407 0,26280128 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,24685407 0,26268504 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,24685407 0,26256891 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,25158752 0,26748545 ! positive regulation of defense response GO:0031349 76 47 0,000 0,25629139 0,2723662 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,25629139 0,27224595 ! JNK cascade GO:0007254 91 47 0,000 0,25629139 0,27212581 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,25629139 0,27200577 ! methylation GO:0032259 90 47 0,000 0,25629139 0,27188584 ! Notch signaling pathway GO:0007219 96 48 0,000 0,26096585 0,27672271 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,26096585 0,27660081 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,26096585 0,27647901 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,26096585 0,27635732 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,26561108 0,28115277 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,26561108 0,28102914 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,26561108 0,28090561 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,26561108 0,28078219 ! peptide metabolic process GO:0006518 76 49 0,000 0,26561108 0,28065887 ! response to temperature stimulus GO:0009266 76 49 0,000 0,26561108 0,28053567 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,26561108 0,28041257 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,26561108 0,28028959 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,26561108 0,28016671 ! regulation of ossification GO:0030278 117 50 0,000 0,27022727 0,28491096 ! inner ear development GO:0048839 79 50 0,000 0,27022727 0,28478616 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,27022727 0,28466147 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,27022727 0,28453689 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,27481459 0,28924055 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,27481459 0,28911408 ! excretion GO:0007588 83 51 0,000 0,27481459 0,28898772 ! chromatin remodeling GO:0006338 109 51 0,000 0,27481459 0,28886147 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,27481459 0,28873533 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,27481459 0,2886093 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,27937323 0,29326876 ! membrane fusion GO:0006944 110 52 0,000 0,27937323 0,29314086 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,28390336 0,29776438 ! RNA catabolic process GO:0006401 93 53 0,000 0,28390336 0,29763464 ! regulation of translational initiation GO:0006446 82 53 0,000 0,28390336 0,297505 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,28390336 0,29737548 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,28390336 0,29724608 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,28390336 0,29711678 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,28390336 0,2969876 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,28840517 0,30156577 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,28840517 0,30143477 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,28840517 0,30130388 ! chloride transport GO:0006821 90 55 0,000 0,29287882 0,30584481 ! glucose catabolic process GO:0006007 82 55 0,000 0,29287882 0,30571212 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,29287882 0,30557955 ! gastrulation GO:0007369 112 55 0,000 0,29287882 0,30544709 ! regulation of actin filament length GO:0030832 105 56 0,000 0,29732449 0,30994919 ! sensory perception of smell GO:0007608 80 56 0,000 0,29732449 0,30981496 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,29732449 0,30968084 ! proton transport GO:0015992 94 56 0,000 0,29732449 0,30954683 ! hydrogen transport GO:0006818 97 58 0,000 0,30613261 0,31857918 ! regulation of endocytosis GO:0030100 91 58 0,000 0,30613261 0,31844144 ! positive regulation of secretion GO:0051047 95 59 0,000 0,31049539 0,32284007 ! regulation of cellular component size GO:0032535 109 59 0,000 0,31049539 0,32270061 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,31049539 0,32256128 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,31049539 0,32242206 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,31483089 0,32678306 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,31913927 0,33111215 ! mesoderm development GO:0007498 119 61 0,000 0,31913927 0,33096943 ! tRNA processing GO:0008033 89 61 0,000 0,31913927 0,33082684 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,31913927 0,33068436 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,3234207 0,33497641 ! gonad development GO:0008406 98 62 0,000 0,3234207 0,33483228 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,32767535 0,33909114 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,33190339 0,34331881 ! cell redox homeostasis GO:0045454 102 64 0,000 0,33190339 0,34317127 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,33190339 0,34302386 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,33190339 0,34287658 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,33190339 0,34272942 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,33610497 0,34691916 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,33610497 0,3467704 ! germ cell development GO:0007281 118 65 0,000 0,33610497 0,34662176 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,34028027 0,35077735 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,34442945 0,35490247 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,34442945 0,35475054 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,34442945 0,35459874 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,34442945 0,35444708 ! hexose catabolic process GO:0019320 104 67 0,000 0,34442945 0,35429554 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,34442945 0,35414413 ! activation of immune response GO:0002253 105 67 0,000 0,34442945 0,35399285 ! amino acid transport GO:0006865 125 68 0,000 0,34855268 0,3580776 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,34855268 0,35792477 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,34855268 0,35777207 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,34855268 0,35761951 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,3526501 0,36166929 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,3526501 0,36151519 ! antigen processing and presentation GO:0019882 104 69 0,000 0,3526501 0,36136122 ! humoral immune response GO:0006959 109 71 0,000 0,3607682 0,36952248 ! regulation of immune effector process GO:0002697 137 71 0,000 0,3607682 0,36936523 ! acute inflammatory response GO:0002526 113 72 0,000 0,3647892 0,37332319 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,3647892 0,37316446 ! carbohydrate transport GO:0008643 110 72 0,000 0,3647892 0,37300587 ! regulation of blood pressure GO:0008217 125 73 0,000 0,36878503 0,37693152 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,36878503 0,37677146 ! fertilization GO:0009566 90 73 0,000 0,36878503 0,37661154 ! transition metal ion transport GO:0000041 126 74 0,000 0,37275586 0,38050514 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,37275586 0,38034377 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,37275586 0,38018254 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,37670185 0,38404434 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,37670185 0,38388168 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,38062313 0,38771349 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,38062313 0,38754941 ! defense response to bacterium GO:0042742 89 76 0,000 0,38062313 0,38738547 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,38062313 0,38722168 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,38062313 0,38705801 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,38451988 0,39085545 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,38451988 0,39069039 ! blood coagulation GO:0007596 146 78 0,000 0,38839224 0,39445831 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,39224037 0,39819845 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,39224037 0,39803051 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,39224037 0,3978627 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,39224037 0,39769504 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,39606441 0,40140311 ! inorganic anion transport GO:0015698 138 80 0,000 0,39606441 0,4012341 ! digestion GO:0007586 112 81 0,000 0,39986452 0,40491331 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,39986452 0,40474297 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,40364084 0,40839355 ! response to nutrient GO:0007584 125 82 0,000 0,40364084 0,40822189 ! hemostasis GO:0007599 158 84 0,000 0,41112272 0,41561398 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,41112272 0,41543942 ! nucleosome assembly GO:0006334 122 85 0,000 0,41482857 0,4190082 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,41482857 0,41883237 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,41851122 0,42237332 ! chromatin assembly GO:0031497 124 86 0,000 0,41851122 0,42219623 ! alcohol catabolic process GO:0046164 130 86 0,000 0,41851122 0,42201928 ! amine transport GO:0015837 155 86 0,000 0,41851122 0,42184248 ! cellular respiration GO:0045333 135 88 0,000 0,42580751 0,42901711 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,42580751 0,42883753 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,42580751 0,4286581 ! cellular defense response GO:0006968 114 89 0,000 0,42942143 0,43211541 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,43301272 0,43554708 ! sterol metabolic process GO:0016125 152 91 0,000 0,43658153 0,43895326 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,43658153 0,43876991 ! regulation of defense response GO:0031347 149 92 0,000 0,44012799 0,44214946 ! nucleosome organization GO:0034728 138 92 0,000 0,44012799 0,44196492 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,44012799 0,44178054 ! vitamin metabolic process GO:0006766 139 92 0,000 0,44012799 0,44159631 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,44365225 0,44494677 ! female pregnancy GO:0007565 164 94 0,000 0,44715444 0,44827232 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,45409316 0,45503879 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,45409316 0,45484935 ! positive regulation of immune response GO:0050778 156 96 0,000 0,45409316 0,45466007 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,45752997 0,45791061 ! protein ubiquitination GO:0016567 217 97 0,000 0,45752997 0,45772021 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,46094525 0,46094525