pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6877-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! DNA damage checkpoint GO:0000077 78 35 6,000 9,133E-10 2,231E-06 ! regulation of DNA replication GO:0006275 105 56 7,000 9,459E-10 1,155E-06 ! DNA integrity checkpoint GO:0031570 82 38 6,000 1,69E-09 1,376E-06 ! regulation of DNA metabolic process GO:0051052 188 97 8,000 4,211E-09 2,572E-06 ! negative regulation of DNA replication GO:0008156 45 25 5,000 4,628E-09 2,261E-06 ! negative regulation of DNA metabolic process GO:0051053 65 35 5,000 4,049E-08 1,649E-05 ! DNA damage response, signal transduction GO:0042770 136 62 6,000 5,879E-08 2,052E-05 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 3,000 6,557E-08 2,002E-05 ! negative regulation of DNA replication initiation GO:0032297 10 8 3,000 6,557E-08 1,78E-05 GO:0000076|DNA replication checkpoint, ! mitotic cell cycle checkpoint GO:0007093 76 39 5,000 7,988E-08 1,951E-05 ! cell cycle checkpoint GO:0000075 145 71 6,000 1,524E-07 3,384E-05 ! regulation of DNA replication initiation GO:0030174 14 10 3,000 1,95E-07 3,97E-05 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 2,000 1,714E-06 3,222E-04 GO:0022011|myelination in the peripheral nervous system, ! filopodium assembly GO:0046847 42 17 3,000 2,143E-06 3,739E-04 ! microspike assembly GO:0030035 46 18 3,000 2,743E-06 4,468E-04 ! nuclear migration GO:0007097 13 6 2,000 3,415E-06 5,214E-04 ! astrocyte development GO:0014002 16 6 2,000 3,415E-06 4,907E-04 ! Schwann cell development GO:0014044 15 6 2,000 3,415E-06 4,635E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 3,415E-06 4,391E-04 GO:0031272|regulation of pseudopodium assembly, ! negative regulation of neuroblast proliferation GO:0007406 25 6 2,000 3,415E-06 4,171E-04 ! prostate gland development GO:0030850 14 7 2,000 5,951E-06 6,923E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 9,482E-06 1,053E-03 ! astrocyte differentiation GO:0048708 19 8 2,000 9,482E-06 1,007E-03 ! ER overload response GO:0006983 13 8 2,000 9,482E-06 9,652E-04 ! Schwann cell differentiation GO:0014037 21 8 2,000 9,482E-06 9,266E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 9,482E-06 8,91E-04 ! protein tetramerization GO:0051262 57 25 3,000 1,1E-05 9,95E-04 ! gland development GO:0048732 220 91 5,000 1,282E-05 1,118E-03 ! myelination GO:0042552 50 26 3,000 1,294E-05 1,09E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 3,000 1,294E-05 1,054E-03 ! macrophage differentiation GO:0030225 15 9 2,000 1,416E-05 1,116E-03 ! response to UV GO:0009411 120 55 4,000 1,45E-05 1,107E-03 ! regulation of bone resorption GO:0045124 25 10 2,000 2,015E-05 1,492E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 3,000 2,029E-05 1,458E-03 ! establishment of organelle localization GO:0051656 122 59 4,000 2,049E-05 1,43E-03 ! regulation of homeostatic process GO:0032844 148 62 4,000 2,612E-05 1,773E-03 ! ensheathment of neurons GO:0007272 64 31 3,000 2,664E-05 1,759E-03 GO:0008366|axon ensheathment, ! nucleus localization GO:0051647 22 11 2,000 2,759E-05 1,774E-03 ! peripheral nervous system development GO:0007422 68 32 3,000 3,032E-05 1,899E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 3,05E-05 1,863E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 3,664E-05 2,183E-03 ! tyrosine metabolic process GO:0006570 19 12 2,000 3,664E-05 2,131E-03 ! autonomic nervous system development GO:0048483 24 12 2,000 3,664E-05 2,082E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 2,000 3,664E-05 2,034E-03 ! cell projection assembly GO:0030031 138 68 4,000 4,095E-05 2,223E-03 ! urogenital system development GO:0001655 149 69 4,000 4,395E-05 2,334E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 6,012E-05 3,125E-03 ! organelle localization GO:0051640 155 74 4,000 6,159E-05 3,135E-03 ! regulation of action potential in neuron GO:0019228 80 40 3,000 7,44E-05 3,709E-03 ! G1/S transition checkpoint GO:0031575 37 15 2,000 7,485E-05 3,657E-03 ! regulation of intracellular protein transport GO:0033157 86 42 3,000 9,033E-05 4,327E-03 ! stem cell development GO:0048864 46 16 2,000 9,174E-05 4,31E-03 GO:0019827|stem cell maintenance, ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 2,000 9,174E-05 4,229E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 9,174E-05 4,15E-03 ! gene silencing by RNA GO:0031047 38 17 2,000 1,109E-04 4,928E-03 ! glial cell development GO:0021782 28 17 2,000 1,109E-04 4,84E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 1,187E-04 5,086E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 1,294E-04 5,451E-03 ! pigmentation GO:0043473 103 46 3,000 1,294E-04 5,358E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,326E-04 5,398E-03 ! cerebral cortex development GO:0021987 40 19 2,000 1,568E-04 6,279E-03 ! regulation of endothelial cell migration GO:0010594 45 19 2,000 1,568E-04 6,178E-03 ! regulation of action potential GO:0001508 102 50 3,000 1,795E-04 6,959E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,837E-04 7,012E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,837E-04 6,904E-03 ! regulation of cell projection organization GO:0031344 135 51 3,000 1,939E-04 7,177E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,134E-04 7,782E-03 ! transcription initiation GO:0006352 171 97 4,000 2,221E-04 7,979E-03 ! leukocyte differentiation GO:0002521 232 98 4,000 2,33E-04 8,248E-03 ! stem cell differentiation GO:0048863 57 22 2,000 2,461E-04 8,589E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 2,461E-04 8,468E-03 ! nucleotide-excision repair GO:0006289 91 57 3,000 2,986E-04 0,01013032 ! regulation of intracellular transport GO:0032386 108 57 3,000 2,986E-04 9,992E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,084E-04 0,01018283 ! hypothalamus development GO:0021854 9 5 1,000 3,084E-04 0,01004706 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 3,084E-04 9,915E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 3,084E-04 9,786E-03 ! lymph vessel development GO:0001945 10 5 1,000 3,084E-04 9,661E-03 ! smooth muscle tissue development GO:0048745 32 5 1,000 3,084E-04 9,538E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 3,084E-04 9,419E-03 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 1,000 3,084E-04 9,303E-03 ! microvillus organization GO:0032528 8 5 1,000 3,084E-04 9,189E-03 GO:0030033|microvillus assembly, ! melanin biosynthetic process from tyrosine GO:0006583 8 5 1,000 3,084E-04 9,079E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,084E-04 8,971E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,084E-04 8,865E-03 ! virus-infected cell apoptosis GO:0006926 7 5 1,000 3,084E-04 8,762E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,084E-04 8,661E-03 ! forebrain morphogenesis GO:0048853 13 5 1,000 3,084E-04 8,563E-03 ! response to mercury ion GO:0046689 8 5 1,000 3,084E-04 8,467E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,084E-04 8,373E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 3,084E-04 8,281E-03 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 3,084E-04 8,191E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 3,193E-04 8,387E-03 ! pallium development GO:0021543 56 24 2,000 3,208E-04 8,337E-03 ! aromatic amino acid family metabolic process GO:0009072 37 24 2,000 3,208E-04 8,25E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 3,208E-04 8,164E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 3,63E-04 9,143E-03 ! interaction with host GO:0051701 66 25 2,000 3,63E-04 9,05E-03 ! regulation of transcription factor import into nucleus GO:0042990 58 26 2,000 4,087E-04 0,01008558 ! negative regulation of cell development GO:0010721 83 26 2,000 4,087E-04 9,985E-03 GO:0050768|negative regulation of neurogenesis, ! skeletal system morphogenesis GO:0048705 118 63 3,000 4,386E-04 0,01060891 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 4,579E-04 0,01096729 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 4,579E-04 0,01086081 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 4,579E-04 0,01075638 ! regulation of chromosome organization GO:0033044 49 27 2,000 4,579E-04 0,01065394 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 4,61E-04 0,0106238 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 4,61E-04 0,01052451 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 1,000 4,61E-04 0,01042707 ! early endosome to late endosome transport GO:0045022 16 6 1,000 4,61E-04 0,0103314 ! establishment of spindle localization GO:0051293 16 6 1,000 4,61E-04 0,01023748 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 4,61E-04 0,01014525 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 1,000 4,61E-04 0,01005467 ! positive regulation of cell motion GO:0051272 157 65 3,000 4,942E-04 0,01068422 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 5,107E-04 0,0109452 ! base-excision repair GO:0006284 41 28 2,000 5,107E-04 0,01085002 ! lung development GO:0030324 165 69 3,000 6,201E-04 0,01306027 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 6,278E-04 0,01310837 ! regulation of helicase activity GO:0051095 16 7 1,000 6,43E-04 0,0133115 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,43E-04 0,01319964 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 6,43E-04 0,01308964 ! mRNA stabilization GO:0048255 18 7 1,000 6,43E-04 0,01298146 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,43E-04 0,01287506 ! regulation of dopamine metabolic process GO:0042053 12 7 1,000 6,43E-04 0,01277038 GO:0042069|regulation of catecholamine metabolic process, ! adrenal gland development GO:0030325 17 7 1,000 6,43E-04 0,01266739 ! nucleoside salvage GO:0043174 11 7 1,000 6,43E-04 0,01256606 GO:0006166|purine ribonucleoside salvage, ! male sex determination GO:0030238 15 7 1,000 6,43E-04 0,01246632 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 6,43E-04 0,01236816 ! B cell lineage commitment GO:0002326 21 7 1,000 6,43E-04 0,01227154 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 6,43E-04 0,01217641 ! T cell lineage commitment GO:0002360 16 7 1,000 6,43E-04 0,01208275 ! melanin biosynthetic process GO:0042438 10 7 1,000 6,43E-04 0,01199051 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 6,922E-04 0,01281081 ! respiratory tube development GO:0030323 171 72 3,000 7,284E-04 0,01337985 ! spindle organization GO:0007051 50 32 2,000 7,607E-04 0,01386791 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 7,607E-04 0,01376518 ! gene silencing GO:0016458 71 32 2,000 7,607E-04 0,01366397 ! respiratory system development GO:0060541 175 74 3,000 8,076E-04 0,01440166 ! negative regulation of protein transport GO:0051224 74 33 2,000 8,333E-04 0,01475172 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 8,541E-04 0,01501166 ! regulation of cellular amine metabolic process GO:0033238 13 8 1,000 8,541E-04 0,01490443 ! meiotic prophase I GO:0007128 14 8 1,000 8,541E-04 0,01479873 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,541E-04 0,01469451 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,541E-04 0,01459175 ! endothelial cell differentiation GO:0045446 17 8 1,000 8,541E-04 0,01449042 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 8,541E-04 0,01439049 ! L-phenylalanine metabolic process GO:0006558 12 8 1,000 8,541E-04 0,01429192 GO:0006559|L-phenylalanine catabolic process, ! melanin metabolic process GO:0006582 17 8 1,000 8,541E-04 0,0141947 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 8,541E-04 0,01409879 ! purine salvage GO:0043101 12 8 1,000 8,541E-04 0,01400417 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,541E-04 0,01391081 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 8,541E-04 0,01381868 ! response to tumor cell GO:0002347 16 8 1,000 8,541E-04 0,01372777 ! regulation of respiratory burst GO:0060263 12 8 1,000 8,541E-04 0,01363804 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 8,541E-04 0,01354949 ! glial cell differentiation GO:0010001 67 34 2,000 9,102E-04 0,01434569 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 9,102E-04 0,01425373 ! telencephalon development GO:0021537 81 35 2,000 9,914E-04 0,01542716 ! protein oligomerization GO:0051259 149 79 3,000 1,032E-03 0,01595584 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,094E-03 0,01681076 ! cell proliferation in forebrain GO:0021846 18 9 1,000 1,094E-03 0,01670569 ! induction of positive chemotaxis GO:0050930 17 9 1,000 1,094E-03 0,01660193 ! artery development GO:0060840 25 9 1,000 1,094E-03 0,01649945 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 20 9 1,000 1,094E-03 0,01639823 ! cerebral cortex cell migration GO:0021795 18 9 1,000 1,094E-03 0,01629824 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,094E-03 0,01619946 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,094E-03 0,01610187 ! receptor clustering GO:0043113 20 9 1,000 1,094E-03 0,01600546 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 1,000 1,094E-03 0,01591019 ! purine base metabolic process GO:0006144 25 9 1,000 1,094E-03 0,01581604 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,094E-03 0,01572301 ! response to hypoxia GO:0001666 178 81 3,000 1,133E-03 0,01618373 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 3,000 1,133E-03 0,01608964 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,167E-03 0,01648471 ! response to oxygen levels GO:0070482 183 83 3,000 1,24E-03 0,01741505 ! meiosis I GO:0007127 74 38 2,000 1,262E-03 0,0176206 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,262E-03 0,01752049 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,362E-03 0,01879594 GO:0042593|glucose homeostasis, ! regulation of developmental growth GO:0048638 16 10 1,000 1,363E-03 0,0187013 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,363E-03 0,01859682 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,363E-03 0,01849351 ! COPI coating of Golgi vesicle GO:0048205 23 10 1,000 1,363E-03 0,01839133 GO:0048200|Golgi transport vesicle coating, ! lung alveolus development GO:0048286 26 10 1,000 1,363E-03 0,01829028 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,363E-03 0,01819033 ! polyamine biosynthetic process GO:0006596 13 10 1,000 1,363E-03 0,01809147 ! epithelial cell development GO:0002064 21 10 1,000 1,363E-03 0,01799368 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,363E-03 0,01789694 ! motor axon guidance GO:0008045 22 10 1,000 1,363E-03 0,01780124 ! protein heterooligomerization GO:0051291 17 10 1,000 1,363E-03 0,01770655 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,363E-03 0,01761286 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 1,000 1,363E-03 0,01752016 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,363E-03 0,01742844 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,363E-03 0,01733766 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,363E-03 0,01724783 ! regulation of protein transport GO:0051223 165 87 3,000 1,477E-03 0,01859443 GO:0070201|regulation of establishment of protein localization, ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,575E-03 0,01973765 ! gliogenesis GO:0042063 91 41 2,000 1,575E-03 0,01963694 ! tube morphogenesis GO:0035239 194 89 3,000 1,606E-03 0,01991249 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,659E-03 0,02047268 ! telencephalon cell migration GO:0022029 23 11 1,000 1,659E-03 0,0203698 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,659E-03 0,02026795 ! Golgi vesicle budding GO:0048194 26 11 1,000 1,659E-03 0,02016712 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,659E-03 0,02006728 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,659E-03 0,01996843 ! blood vessel remodeling GO:0001974 30 11 1,000 1,659E-03 0,01987054 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,659E-03 0,01977361 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,659E-03 0,01967763 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,659E-03 0,01958256 ! cellular metabolic compound salvage GO:0043094 16 11 1,000 1,659E-03 0,01948842 ! prophase GO:0051324 17 11 1,000 1,659E-03 0,01939517 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,659E-03 0,01930281 ! regulation of embryonic development GO:0045995 35 11 1,000 1,659E-03 0,01921133 ! T cell differentiation GO:0030217 93 42 2,000 1,69E-03 0,01947137 ! ossification GO:0001503 205 91 3,000 1,742E-03 0,01998539 ! neuron migration GO:0001764 85 43 2,000 1,809E-03 0,02065121 ! bone development GO:0060348 206 92 3,000 1,814E-03 0,02060993 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 1,887E-03 0,02134382 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,887E-03 0,02124546 ! double-strand break repair GO:0006302 85 44 2,000 1,933E-03 0,02166658 ! regulation of membrane potential GO:0042391 179 94 3,000 1,962E-03 0,021892 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,984E-03 0,02202912 ! virus-host interaction GO:0019048 30 12 1,000 1,984E-03 0,02192944 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,984E-03 0,02183066 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 1,984E-03 0,02173276 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,984E-03 0,02163574 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,984E-03 0,02153958 ! polyamine metabolic process GO:0006595 18 12 1,000 1,984E-03 0,02144428 ! mitotic spindle organization GO:0007052 23 12 1,000 1,984E-03 0,02134981 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 1,000 1,984E-03 0,02125617 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 1,000 1,984E-03 0,02116335 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 1,000 1,984E-03 0,02107133 ! entry into host cell GO:0030260 34 12 1,000 1,984E-03 0,02098012 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! cranial nerve development GO:0021545 23 12 1,000 1,984E-03 0,02088968 ! histone acetylation GO:0016573 27 12 1,000 1,984E-03 0,02080003 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,984E-03 0,02071114 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,984E-03 0,02062301 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,984E-03 0,02053562 GO:0042130|negative regulation of T cell proliferation, ! localization within membrane GO:0051668 26 12 1,000 1,984E-03 0,02044897 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 2,063E-03 0,02117641 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 2,063E-03 0,0210878 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 2,198E-03 0,02237315 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 2,198E-03 0,02228031 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,198E-03 0,02218825 ! regulation of protein localization GO:0032880 188 97 3,000 2,201E-03 0,02212762 ! forebrain development GO:0030900 210 98 3,000 2,285E-03 0,02287542 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,336E-03 0,02329184 GO:0000725|recombinational repair, ! cartilage condensation GO:0001502 22 13 1,000 2,336E-03 0,02319716 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 2,336E-03 0,02310324 ! response to X-ray GO:0010165 28 13 1,000 2,336E-03 0,02301009 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 2,336E-03 0,02291768 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,336E-03 0,022826 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! protein homotetramerization GO:0051289 24 13 1,000 2,336E-03 0,02273506 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,336E-03 0,02264485 ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 2,336E-03 0,02255534 ! regulation of mRNA stability GO:0043488 32 13 1,000 2,336E-03 0,02246654 ! positive regulation of homeostatic process GO:0032846 23 13 1,000 2,336E-03 0,02237844 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 1,000 2,336E-03 0,02229102 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,336E-03 0,02220428 ! response to insulin stimulus GO:0032868 98 47 2,000 2,338E-03 0,02214033 ! positive regulation of cell cycle GO:0045787 96 48 2,000 2,484E-03 0,02342898 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,635E-03 0,02475935 ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 1,000 2,715E-03 0,02541419 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 2,715E-03 0,02531719 ! regulation of cellular pH GO:0030641 27 14 1,000 2,715E-03 0,02522093 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 2,715E-03 0,02512539 ! response to gamma radiation GO:0010332 30 14 1,000 2,715E-03 0,02503058 ! regulation of RNA stability GO:0043487 33 14 1,000 2,715E-03 0,02493648 ! regulation of calcium-mediated signaling GO:0050848 29 14 1,000 2,715E-03 0,02484309 ! endocrine system development GO:0035270 109 50 2,000 2,792E-03 0,02544905 ! activation of caspase activity GO:0006919 95 50 2,000 2,792E-03 0,02535444 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 3,121E-03 0,02824241 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 3,121E-03 0,0281382 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 3,121E-03 0,02803475 ! vesicle coating GO:0006901 38 15 1,000 3,121E-03 0,02793206 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 3,121E-03 0,02783011 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 3,121E-03 0,02772891 ! histone deacetylation GO:0016575 24 15 1,000 3,121E-03 0,02762845 ! positive regulation of calcium ion transport GO:0051928 21 15 1,000 3,121E-03 0,02752871 ! histone modification GO:0016570 104 52 2,000 3,122E-03 0,02743737 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 2,000 3,122E-03 0,02733903 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 3,122E-03 0,02724139 ! positive regulation of growth GO:0045927 96 53 2,000 3,296E-03 0,02865563 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 3,296E-03 0,02855401 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 2,000 3,296E-03 0,02845311 ! regulation of angiogenesis GO:0045765 125 54 2,000 3,476E-03 0,0298982 ! covalent chromatin modification GO:0016569 115 54 2,000 3,476E-03 0,0297933 ! regulation of cell shape GO:0008360 142 54 2,000 3,476E-03 0,02968912 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,554E-03 0,03025361 ! positive regulation of ion transport GO:0043270 23 16 1,000 3,554E-03 0,03014856 ! startle response GO:0001964 28 16 1,000 3,554E-03 0,03004424 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,554E-03 0,02994064 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 3,554E-03 0,02983775 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,554E-03 0,02973557 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 3,554E-03 0,02963408 ! pituitary gland development GO:0021983 30 16 1,000 3,554E-03 0,02953328 ! neuron recognition GO:0008038 40 16 1,000 3,554E-03 0,02943317 ! RNA elongation GO:0006354 90 56 2,000 3,853E-03 0,03179741 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 4,013E-03 0,03301129 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 4,013E-03 0,03290052 ! signal complex assembly GO:0007172 47 17 1,000 4,013E-03 0,03279048 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 4,013E-03 0,03268118 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 4,013E-03 0,03257261 ! regulation of survival gene product expression GO:0045884 38 17 1,000 4,013E-03 0,03246475 ! membrane budding GO:0006900 42 17 1,000 4,013E-03 0,03235761 ! nucleobase metabolic process GO:0009112 43 17 1,000 4,013E-03 0,03225117 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 4,013E-03 0,03214542 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 4,013E-03 0,03204037 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 4,05E-03 0,03222933 ! regulation of bone remodeling GO:0046850 143 57 2,000 4,05E-03 0,03212469 ! positive regulation of caspase activity GO:0043280 108 57 2,000 4,05E-03 0,03202073 GO:0010952|positive regulation of peptidase activity, ! regulation of tissue remodeling GO:0034103 146 58 2,000 4,254E-03 0,03352114 ! limbic system development GO:0021761 40 18 1,000 4,498E-03 0,03533574 ! patterning of blood vessels GO:0001569 43 18 1,000 4,498E-03 0,03522248 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 4,498E-03 0,03510995 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,498E-03 0,03499813 ! nerve development GO:0021675 34 18 1,000 4,498E-03 0,03488703 ! DNA catabolic process GO:0006308 94 60 2,000 4,679E-03 0,03617315 ! kidney development GO:0001822 133 60 2,000 4,679E-03 0,03605903 ! pigmentation during development GO:0048066 42 19 1,000 5,009E-03 0,03848184 ! neuromuscular junction development GO:0007528 43 19 1,000 5,009E-03 0,0383612 ! protein export from nucleus GO:0006611 40 19 1,000 5,009E-03 0,03824133 ! visual learning GO:0008542 38 19 1,000 5,009E-03 0,03812219 ! viral reproductive process GO:0022415 132 62 2,000 5,129E-03 0,03891468 ! regulation of protein complex assembly GO:0043254 132 63 2,000 5,364E-03 0,04056804 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 5,545E-03 0,04181189 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,545E-03 0,04168324 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 1,000 5,545E-03 0,04155538 ! protein amino acid deacetylation GO:0006476 34 20 1,000 5,545E-03 0,0414283 ! protein amino acid acetylation GO:0006473 41 20 1,000 5,545E-03 0,04130199 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,545E-03 0,04117646 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 5,545E-03 0,04105168 ! response to alkaloid GO:0043279 38 20 1,000 5,545E-03 0,04092765 ! cellular response to unfolded protein GO:0034620 35 20 1,000 5,545E-03 0,04080438 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 5,545E-03 0,04068184 ! aromatic compound catabolic process GO:0019439 31 20 1,000 5,545E-03 0,04056004 ! negative regulation of T cell activation GO:0050868 41 20 1,000 5,545E-03 0,04043897 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 5,605E-03 0,04074984 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 6,106E-03 0,04426074 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 6,106E-03 0,04412979 ! lipid phosphorylation GO:0046834 43 21 1,000 6,106E-03 0,04400642 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 6,106E-03 0,04387699 ! diencephalon development GO:0021536 36 21 1,000 6,106E-03 0,04374832 ! collagen fibril organization GO:0030199 62 21 1,000 6,106E-03 0,0436204 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 6,106E-03 0,04349322 ! camera-type eye morphogenesis GO:0048593 47 21 1,000 6,106E-03 0,04336679 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 6,106E-03 0,04324109 ! negative regulation of cell growth GO:0030308 142 67 2,000 6,366E-03 0,04494664 ! myeloid cell differentiation GO:0030099 126 67 2,000 6,366E-03 0,04481711 ! viral reproduction GO:0016032 142 68 2,000 6,632E-03 0,04656076 ! hindlimb morphogenesis GO:0035137 47 22 1,000 6,693E-03 0,04684776 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 6,693E-03 0,04671391 ! cellular response to starvation GO:0009267 37 22 1,000 6,693E-03 0,04658082 ! apoptotic nuclear changes GO:0030262 34 22 1,000 6,693E-03 0,04644849 ! cell aging GO:0007569 48 22 1,000 6,693E-03 0,04631691 ! positive regulation of locomotion GO:0040017 44 22 1,000 6,693E-03 0,04618607 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 6,693E-03 0,04605597 ! peptidyl-serine modification GO:0018209 50 22 1,000 6,693E-03 0,0459266 ! sarcomere organization GO:0045214 32 22 1,000 6,693E-03 0,04579795 ! positive regulation of B cell activation GO:0050871 42 22 1,000 6,693E-03 0,04567003 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,693E-03 0,04554281 ! protein stabilization GO:0050821 41 22 1,000 6,693E-03 0,0454163 ! negative regulation of cell size GO:0045792 144 69 2,000 6,906E-03 0,04673349 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 6,906E-03 0,04660439 ! negative regulation of kinase activity GO:0033673 145 70 2,000 7,186E-03 0,04835968 ! positive regulation of DNA replication GO:0045740 44 23 1,000 7,303E-03 0,04901489 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 7,303E-03 0,04888061 ! regulation of chemotaxis GO:0050920 45 23 1,000 7,303E-03 0,04874705 ! visual behavior GO:0007632 46 23 1,000 7,303E-03 0,04861423 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 7,303E-03 0,04848212 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 7,303E-03 0,04835073 ! vesicle targeting GO:0006903 49 23 1,000 7,303E-03 0,04822006 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 7,303E-03 0,04809008 ! regulation of Rho GTPase activity GO:0032319 56 23 1,000 7,303E-03 0,04796081 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 7,303E-03 0,04783223 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 7,472E-03 0,04880898 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,938E-03 0,05171233 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 7,938E-03 0,05157479 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 7,938E-03 0,05143799 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 7,938E-03 0,05130191 ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 7,938E-03 0,05116655 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 1,000 7,938E-03 0,0510319 ! sex determination GO:0007530 48 24 1,000 7,938E-03 0,05089796 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 7,938E-03 0,05076472 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 7,938E-03 0,05063217 ! negative regulation of catabolic process GO:0009895 52 24 1,000 7,938E-03 0,05050032 ! regulation of caspase activity GO:0043281 136 74 2,000 8,372E-03 0,05312401 ! negative regulation of transferase activity GO:0051348 155 74 2,000 8,372E-03 0,05298638 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 8,597E-03 0,05426685 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 8,597E-03 0,05412699 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 8,597E-03 0,05398784 ! vasculogenesis GO:0001570 49 25 1,000 8,597E-03 0,05384941 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 8,597E-03 0,05371169 ! receptor metabolic process GO:0043112 53 25 1,000 8,597E-03 0,05357467 ! regulation of behavior GO:0050795 48 25 1,000 8,597E-03 0,05343835 ! liver development GO:0001889 55 25 1,000 8,597E-03 0,05330272 ! regulation of transcription factor activity GO:0051090 137 75 2,000 8,685E-03 0,05371766 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 2,000 8,685E-03 0,05358201 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 8,685E-03 0,05344704 ! learning or memory GO:0007611 161 76 2,000 9,006E-03 0,0552785 ! lymphocyte differentiation GO:0030098 193 76 2,000 9,006E-03 0,05513995 ! initiation of viral infection GO:0019059 60 26 1,000 9,279E-03 0,05667043 ! spinal cord development GO:0021510 54 26 1,000 9,279E-03 0,05652911 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 9,279E-03 0,05638849 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 9,279E-03 0,05624856 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 1,000 9,279E-03 0,05610933 ! positive regulation of nuclear division GO:0051785 41 26 1,000 9,279E-03 0,05597079 GO:0045840|positive regulation of mitosis, ! neural tube closure GO:0001843 58 26 1,000 9,279E-03 0,05583293 GO:0060606|tube closure, ! regulation of endopeptidase activity GO:0052548 141 77 2,000 9,333E-03 0,05601944 ! regulation of catabolic process GO:0009894 173 77 2,000 9,333E-03 0,05588214 ! tube lumen formation GO:0035148 59 27 1,000 9,984E-03 0,05963846 ! mitochondrial membrane organization GO:0007006 60 27 1,000 9,984E-03 0,059493 ! response to starvation GO:0042594 47 27 1,000 9,984E-03 0,05934825 ! cellular response to nutrient levels GO:0031669 45 27 1,000 9,984E-03 0,0592042 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 9,984E-03 0,05906085 ! meiosis GO:0007126 143 81 2,000 0,01071003 0,06319951 GO:0051327|M phase of meiotic cell cycle, ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01071325 0,06306619 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01071325 0,06291459 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 0,01071325 0,06276371 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01107171 0,06470858 ! meiotic cell cycle GO:0051321 144 82 2,000 0,01107171 0,06455415 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 0,01144039 0,06654491 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,0114648 0,06652851 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,0114648 0,06637086 ! primary neural tube formation GO:0014020 61 29 1,000 0,0114648 0,06621396 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,0114648 0,06605779 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 0,0114648 0,06590236 ! somitogenesis GO:0001756 52 29 1,000 0,0114648 0,06574766 ! response to metal ion GO:0010038 158 84 2,000 0,01181608 0,06760345 ! T cell activation GO:0042110 189 84 2,000 0,01181608 0,0674455 ! negative regulation of transport GO:0051051 164 85 2,000 0,0121988 0,06946777 ! negative regulation of growth GO:0045926 168 85 2,000 0,0121988 0,06930622 ! regulation of cyclase activity GO:0031279 168 85 2,000 0,0121988 0,06914542 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 0,0121988 0,06898536 ! myofibril assembly GO:0030239 50 30 1,000 0,01223887 0,06905211 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 0,01223887 0,068893 ! cell fate determination GO:0001709 64 30 1,000 0,01223887 0,06873462 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01223887 0,06857698 ! neurotransmitter secretion GO:0007269 55 30 1,000 0,01223887 0,06842005 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01223887 0,06826384 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01223887 0,06810834 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 0,01258858 0,06989525 ! regulation of lyase activity GO:0051339 169 86 2,000 0,01258858 0,06973676 ! mitochondrion organization GO:0007005 159 87 2,000 0,01298544 0,07177247 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01303519 0,07188483 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01303519 0,07172292 ! eye morphogenesis GO:0048592 65 31 1,000 0,01303519 0,07156175 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 0,01380045 0,07559304 ! regulation of DNA binding GO:0051101 167 89 2,000 0,01380045 0,07542393 ! metanephros development GO:0001656 81 32 1,000 0,0138535 0,07554484 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,0138535 0,07537659 ! muscle cell development GO:0055001 52 32 1,000 0,0138535 0,07520909 ! hindbrain development GO:0030902 65 32 1,000 0,0138535 0,07504233 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,0138535 0,07487631 ! response to inorganic substance GO:0010035 173 90 2,000 0,01421863 0,07668018 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 0,01464396 0,07879996 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of pH GO:0006885 56 33 1,000 0,01469351 0,07889284 ! pigment biosynthetic process GO:0046148 73 33 1,000 0,01469351 0,07871983 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01469351 0,07854757 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01469351 0,07837607 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,01469351 0,07820532 ! regulation of calcium ion transport GO:0051924 60 33 1,000 0,01469351 0,07803531 ! establishment of vesicle localization GO:0051650 67 33 1,000 0,01469351 0,07786603 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01507643 0,07972235 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01555497 0,08207513 ! adult locomotory behavior GO:0008344 62 34 1,000 0,01555497 0,08189824 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 0,01641691 0,08625056 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,0164376 0,08617397 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,0164376 0,08598944 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,0164376 0,0858057 ! vesicle localization GO:0051648 70 35 1,000 0,0164376 0,08562275 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01734116 0,09013715 ! regulation of muscle development GO:0048634 82 36 1,000 0,01734116 0,08994578 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01734116 0,08975521 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01734116 0,08956546 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,01782217 0,09185564 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 0,01782217 0,09166226 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01826538 0,09374438 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01826538 0,09354785 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01826538 0,09335214 ! actomyosin structure organization GO:0031032 68 37 1,000 0,01826538 0,09315725 ! tissue remodeling GO:0048771 78 37 1,000 0,01826538 0,09296317 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01826538 0,0927699 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01826538 0,09257743 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01879513 0,0950652 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01921 0,09696287 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,01921 0,09676295 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01921 0,09656385 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,01921 0,09636557 ! regulation of protein stability GO:0031647 77 38 1,000 0,01921 0,09616809 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01921 0,09597143 ! pigment metabolic process GO:0042440 87 38 1,000 0,01921 0,09577557 ! neural tube formation GO:0001841 79 38 1,000 0,01921 0,09558051 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,02017477 0,10017674 ! regulation of metal ion transport GO:0010959 71 39 1,000 0,02017477 0,09997354 ! negative regulation of binding GO:0051100 71 39 1,000 0,02017477 0,09977117 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,02017477 0,09956961 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,02017477 0,09936887 ! glucan metabolic process GO:0044042 64 39 1,000 0,02017477 0,09916893 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,02115943 0,10380017 ! learning GO:0007612 82 40 1,000 0,02115943 0,10359216 ! nucleus organization GO:0006997 73 40 1,000 0,02115943 0,10338497 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,02115943 0,10317862 ! RNA export from nucleus GO:0006405 61 41 1,000 0,02216374 0,10786057 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,02216374 0,10764614 ! maintenance of protein location GO:0045185 95 41 1,000 0,02216374 0,10743255 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,02216374 0,10721982 ! ear morphogenesis GO:0042471 64 42 1,000 0,02318744 0,11195042 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 0,02318744 0,11172961 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,02318744 0,11150967 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,02318744 0,11129059 ! cytokinesis GO:0000910 84 42 1,000 0,02318744 0,11107237 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02423029 0,1158407 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02423029 0,11561445 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02423029 0,11538908 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02423029 0,11516458 ! segmentation GO:0035282 78 43 1,000 0,02423029 0,11494096 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,02529205 0,11974509 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,02529205 0,11951348 ! B cell differentiation GO:0030183 124 45 1,000 0,02637246 0,12437825 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02637246 0,1241386 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02747131 0,12906231 ! cell growth GO:0016049 90 46 1,000 0,02747131 0,12881459 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02768331 0,12956001 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02768331 0,12931228 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02768331 0,12906551 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02768331 0,12881967 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02768331 0,12857476 ! neuron fate determination GO:0048664 7 5 0,000 0,02768331 0,12833079 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02768331 0,12808774 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02768331 0,1278456 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02768331 0,12760439 ! polyol transport GO:0015791 12 5 0,000 0,02768331 0,12736408 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02768331 0,12712467 ! response to superoxide GO:0000303 10 5 0,000 0,02768331 0,12688616 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02768331 0,12664855 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02768331 0,12641182 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02768331 0,12617598 ! female meiosis GO:0007143 10 5 0,000 0,02768331 0,12594101 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02768331 0,12570692 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02768331 0,1254737 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02768331 0,12524134 ! cobalt ion transport GO:0006824 11 5 0,000 0,02768331 0,12500984 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02768331 0,1247792 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02768331 0,1245494 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02768331 0,12432045 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02768331 0,12409234 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02768331 0,12386506 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02768331 0,12363862 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02768331 0,123413 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02768331 0,12318821 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02768331 0,12296423 ! transposition GO:0032196 9 5 0,000 0,02768331 0,12274106 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02768331 0,1225187 ! negative chemotaxis GO:0050919 16 5 0,000 0,02768331 0,12229715 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02768331 0,1220764 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02768331 0,12185644 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02768331 0,12163727 ! behavioral response to pain GO:0048266 10 5 0,000 0,02768331 0,1214189 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02768331 0,1212013 ! Notch receptor processing GO:0007220 11 5 0,000 0,02768331 0,12098448 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02768331 0,12076844 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02768331 0,12055316 ! micturition GO:0060073 9 5 0,000 0,02768331 0,12033866 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02768331 0,12012491 ! copulation GO:0007620 9 5 0,000 0,02768331 0,11991192 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02768331 0,11969969 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02768331 0,11948821 ! bioluminescence GO:0008218 9 5 0,000 0,02768331 0,11927747 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02768331 0,11906747 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02768331 0,11885822 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02768331 0,11864969 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02768331 0,1184419 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02768331 0,11823483 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02768331 0,11802849 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02768331 0,11782287 ! grooming behavior GO:0007625 6 5 0,000 0,02768331 0,11761796 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02768331 0,11741376 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02768331 0,11721027 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02768331 0,11700748 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02768331 0,1168054 ! response to protozoan GO:0001562 13 5 0,000 0,02768331 0,11660401 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02768331 0,11640331 ! endochondral ossification GO:0001958 17 5 0,000 0,02768331 0,11620331 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02768331 0,11600399 ! single strand break repair GO:0000012 8 5 0,000 0,02768331 0,11580535 ! parathyroid gland development GO:0060017 14 5 0,000 0,02768331 0,11560739 ! anagen GO:0042640 7 5 0,000 0,02768331 0,11541011 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02768331 0,1152135 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02768331 0,11501756 ! cytokine secretion GO:0050663 15 5 0,000 0,02768331 0,11482228 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02768331 0,11462767 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02768331 0,11443371 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02768331 0,11424041 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02768331 0,11404777 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02768331 0,11385577 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02768331 0,11366441 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02768331 0,1134737 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02768331 0,11328363 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02768331 0,11309419 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02768331 0,11290538 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02768331 0,11271721 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02768331 0,11252966 ! valine metabolic process GO:0006573 12 5 0,000 0,02768331 0,11234273 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02768331 0,11215643 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02768331 0,11197074 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02768331 0,11178566 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02768331 0,1116012 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02768331 0,11141734 ! polyol catabolic process GO:0046174 9 5 0,000 0,02768331 0,11123409 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02768331 0,11105144 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02768331 0,11086938 ! muscle cell migration GO:0014812 8 5 0,000 0,02768331 0,11068793 ! mitochondrial fission GO:0000266 8 5 0,000 0,02768331 0,11050707 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02768331 0,11032679 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02768331 0,11014711 ! mRNA transcription GO:0009299 10 5 0,000 0,02768331 0,10996801 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02768331 0,10978949 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02768331 0,10961155 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02768331 0,10943418 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02768331 0,10925739 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02768331 0,10908117 ! monocyte activation GO:0042117 10 5 0,000 0,02768331 0,10890552 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02768331 0,10873043 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02768331 0,1085559 ! response to food GO:0032094 6 5 0,000 0,02768331 0,10838193 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02768331 0,10820852 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02768331 0,10803566 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02768331 0,10786336 ! forebrain neuron development GO:0021884 13 5 0,000 0,02768331 0,1076916 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02768331 0,10752039 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02768331 0,10734972 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02768331 0,1071796 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02768331 0,10701001 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02768331 0,10684096 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02768331 0,10667244 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02768331 0,10650445 ! lipid glycosylation GO:0030259 7 5 0,000 0,02768331 0,10633699 ! nucleobase transport GO:0015851 6 5 0,000 0,02768331 0,10617005 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02768331 0,10600364 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02768331 0,10583775 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02768331 0,10567238 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02768331 0,10550753 ! basic amino acid transport GO:0015802 12 5 0,000 0,02768331 0,10534319 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02768331 0,10517935 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02768331 0,10501603 ! actin nucleation GO:0045010 11 5 0,000 0,02768331 0,10485322 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02768331 0,10469091 ! depurination GO:0045007 5 5 0,000 0,02768331 0,1045291 ! depyrimidination GO:0045008 10 5 0,000 0,02768331 0,10436779 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02768331 0,10420697 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02768331 0,10404665 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02768331 0,10388683 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02768331 0,10372749 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02768331 0,10356864 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02768331 0,10341028 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02768331 0,1032524 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02768331 0,10309501 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02768331 0,10293809 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02768331 0,10278165 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02768331 0,10262568 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02768331 0,10247019 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02768331 0,10231517 ! response to arsenic GO:0046685 11 5 0,000 0,02768331 0,10216061 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02768331 0,10200652 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02768331 0,1018529 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02768331 0,10169974 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02768331 0,10154703 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02768331 0,10139479 ! response to cadmium ion GO:0046686 7 5 0,000 0,02768331 0,101243 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02768331 0,10109167 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02768331 0,10094078 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02768331 0,10079035 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02768331 0,10064036 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02768331 0,10049082 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02768331 0,10034173 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02768331 0,10019307 ! decidualization GO:0046697 11 5 0,000 0,02768331 0,10004486 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02768331 0,09989708 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02768331 0,09974974 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02768331 0,09960283 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02768331 0,09945636 ! embryonic cleavage GO:0040016 6 5 0,000 0,02768331 0,09931032 ! peroxisome fission GO:0016559 5 5 0,000 0,02768331 0,0991647 ! histone demethylation GO:0016577 13 5 0,000 0,02768331 0,09901951 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02768331 0,09887474 ! mitotic recombination GO:0006312 9 5 0,000 0,02768331 0,0987304 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02768331 0,09858648 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02768331 0,09844298 ! metaphase plate congression GO:0051310 7 5 0,000 0,02768331 0,09829989 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02768331 0,09815722 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02768331 0,09801496 ! enteric nervous system development GO:0048484 8 5 0,000 0,02768331 0,09787312 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02768331 0,09773168 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02768331 0,09759066 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02768331 0,09745004 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02768331 0,09730982 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02768331 0,09717001 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02768331 0,0970306 ! B cell homeostasis GO:0001782 13 5 0,000 0,02768331 0,09689158 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02768331 0,09675297 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02768331 0,09661475 ! metaphase GO:0051323 11 5 0,000 0,02768331 0,09647693 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02768331 0,09633949 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02768331 0,09620245 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02768331 0,0960658 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02768331 0,09592954 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02768331 0,09579366 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02768331 0,09565817 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02768331 0,09552306 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02768331 0,09538833 ! response to redox state GO:0051775 6 5 0,000 0,02768331 0,09525398 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02768331 0,09512001 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02768331 0,09498641 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02768331 0,09485319 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02768331 0,09472034 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02768331 0,09458787 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02768331 0,09445576 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02768331 0,09432402 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02768331 0,09419265 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02768331 0,09406165 ! striatum development GO:0021756 14 5 0,000 0,02768331 0,09393101 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02768331 0,09380073 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02768331 0,09367081 ! glial cell migration GO:0008347 10 5 0,000 0,02768331 0,09354125 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02768331 0,09341205 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02768331 0,09328321 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02768331 0,09315472 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02768331 0,09302658 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02768331 0,0928988 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02768331 0,09277136 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02768331 0,09264428 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02768331 0,09251754 ! neuroprotection GO:0043526 8 5 0,000 0,02768331 0,09239115 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02768331 0,09226511 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02768331 0,09213941 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02768331 0,09201405 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02768331 0,09188903 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02768331 0,09176435 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02768331 0,09164001 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02768331 0,091516 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02768331 0,09139233 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02768331 0,09126899 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02768331 0,09114599 ! spindle assembly GO:0051225 6 5 0,000 0,02768331 0,09102332 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02768331 0,09090097 ! protein palmitoylation GO:0018345 12 5 0,000 0,02768331 0,09077896 ! drug metabolic process GO:0017144 7 5 0,000 0,02768331 0,09065727 ! stem cell division GO:0017145 11 5 0,000 0,02768331 0,09053591 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02768331 0,09041487 ! organ regeneration GO:0031100 7 5 0,000 0,02768331 0,09029416 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02768331 0,09017377 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02768331 0,09005369 ! neural tube development GO:0021915 91 47 1,000 0,02858833 0,09287407 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 0,02972331 0,096433 ! mitochondrial transport GO:0006839 94 48 1,000 0,02972331 0,0963051 ! cellular component disassembly GO:0022411 89 48 1,000 0,02972331 0,09617755 ! endosome transport GO:0016197 127 48 1,000 0,02972331 0,09605033 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02972331 0,09592345 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02972331 0,0957969 ! response to calcium ion GO:0051592 94 49 1,000 0,030876 0,09938086 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,030876 0,0992501 ! positive regulation of cyclase activity GO:0031281 106 49 1,000 0,030876 0,09911968 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,030876 0,0989896 ! protein homooligomerization GO:0051260 84 49 1,000 0,030876 0,09885986 ! regulation of ion transport GO:0043269 86 50 1,000 0,03204618 0,10247227 ! positive regulation of lyase activity GO:0051349 107 50 1,000 0,03204618 0,10233832 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03312778 0,10565426 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03312778 0,10551651 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03312778 0,10537912 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03312778 0,10524209 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03312778 0,10510541 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03312778 0,10496909 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03312778 0,10483312 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03312778 0,1046975 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03312778 0,10456223 ! response to oxygen radical GO:0000305 11 6 0,000 0,03312778 0,10442731 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03312778 0,10429274 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03312778 0,10415851 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03312778 0,10402463 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03312778 0,1038911 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03312778 0,1037579 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03312778 0,10362505 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03312778 0,10349254 ! forebrain regionalization GO:0021871 9 6 0,000 0,03312778 0,10336036 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03312778 0,10322853 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03312778 0,10309703 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03312778 0,10296586 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03312778 0,10283503 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03312778 0,10270452 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03312778 0,10257435 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03312778 0,10244451 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03312778 0,102315 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03312778 0,10218581 ! malate metabolic process GO:0006108 13 6 0,000 0,03312778 0,10205695 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03312778 0,10192842 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03312778 0,10180021 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03312778 0,10167232 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03312778 0,10154475 ! protein refolding GO:0042026 15 6 0,000 0,03312778 0,1014175 ! opsonization GO:0008228 8 6 0,000 0,03312778 0,10129057 ! mating behavior GO:0007617 7 6 0,000 0,03312778 0,10116396 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03312778 0,10103766 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03312778 0,10091168 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03312778 0,10078601 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03312778 0,10066065 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03312778 0,10053561 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03312778 0,10041087 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03312778 0,10028645 ! toxin metabolic process GO:0009404 11 6 0,000 0,03312778 0,10016233 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03312778 0,10003852 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03312778 0,09991502 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03312778 0,09979182 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03312778 0,09966892 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03312778 0,09954633 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03312778 0,09942404 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03312778 0,09930204 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03312778 0,09918035 ! thymic T cell selection GO:0045061 16 6 0,000 0,03312778 0,09905895 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03312778 0,09893785 ! protein lipoylation GO:0009249 10 6 0,000 0,03312778 0,09881705 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03312778 0,09869654 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03312778 0,09857633 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03312778 0,09845641 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03312778 0,09833677 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03312778 0,09821743 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03312778 0,09809838 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03312778 0,09797962 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03312778 0,09786114 ! hyperosmotic response GO:0006972 10 6 0,000 0,03312778 0,09774295 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03312778 0,09762505 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03312778 0,09750743 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03312778 0,09739009 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03312778 0,09727304 ! urea metabolic process GO:0019627 7 6 0,000 0,03312778 0,09715626 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03312778 0,09703977 ! neutrophil activation GO:0042119 7 6 0,000 0,03312778 0,09692355 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03312778 0,09680761 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03312778 0,09669195 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03312778 0,09657657 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03312778 0,09646146 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03312778 0,09634663 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03312778 0,09623206 ! neuron apoptosis GO:0051402 15 6 0,000 0,03312778 0,09611777 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03312778 0,09600375 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03312778 0,09589001 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03312778 0,09577653 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03312778 0,09566332 ! carnitine transport GO:0015879 10 6 0,000 0,03312778 0,09555037 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03312778 0,09543769 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03312778 0,09532528 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03312778 0,09521314 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03312778 0,09510125 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03312778 0,09498963 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03312778 0,09487827 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03312778 0,09476717 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03312778 0,09465633 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03312778 0,09454575 ! response to UV-C GO:0010225 14 6 0,000 0,03312778 0,09443543 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03312778 0,09432537 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03312778 0,09421556 ! interaction with symbiont GO:0051702 14 6 0,000 0,03312778 0,09410601 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03312778 0,09399671 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03312778 0,09388766 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03312778 0,09377887 ! response to copper ion GO:0046688 10 6 0,000 0,03312778 0,09367033 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03312778 0,09356204 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03312778 0,093454 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03312778 0,09334621 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03312778 0,09323867 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03312778 0,09313138 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03312778 0,09302433 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03312778 0,09291753 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03312778 0,09281097 ! hair follicle maturation GO:0048820 8 6 0,000 0,03312778 0,09270466 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03312778 0,09259859 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03312778 0,09249276 ! response to pheromone GO:0019236 6 6 0,000 0,03312778 0,09238717 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03312778 0,09228183 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03312778 0,09217673 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03312778 0,09207186 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03312778 0,09196723 ! subpallium development GO:0021544 15 6 0,000 0,03312778 0,09186284 ! neural tube patterning GO:0021532 8 6 0,000 0,03312778 0,09175869 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03312778 0,09165477 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03312778 0,09155109 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03312778 0,09144764 ! G2 phase GO:0051319 16 6 0,000 0,03312778 0,09134443 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03312778 0,09124145 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03312778 0,0911387 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03312778 0,09103618 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03312778 0,09093389 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03312778 0,09083184 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03312778 0,09073001 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03312778 0,0906284 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03312778 0,09052703 ! receptor internalization GO:0031623 11 6 0,000 0,03312778 0,09042588 ! plasminogen activation GO:0031639 9 6 0,000 0,03312778 0,09032496 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03312778 0,09022426 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03312778 0,09012379 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03312778 0,09002354 ! protein deubiquitination GO:0016579 16 6 0,000 0,03312778 0,08992352 ! protein destabilization GO:0031648 9 6 0,000 0,03312778 0,08982371 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03312778 0,08972413 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03312778 0,08962477 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03312778 0,08952563 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03312778 0,0894267 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03312778 0,089328 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03312778 0,08922951 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03312778 0,08913124 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03312778 0,08903319 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03312778 0,08893535 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03312778 0,08883772 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03312778 0,08874031 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03312778 0,08864312 ! neural plate development GO:0001840 9 6 0,000 0,03312778 0,08854613 ! catecholamine transport GO:0051937 9 6 0,000 0,03312778 0,08844936 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03312778 0,0883528 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03312778 0,08825645 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03312778 0,08816031 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03312778 0,08806438 ! maternal placenta development GO:0001893 12 6 0,000 0,03312778 0,08796866 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03312778 0,08787314 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03312778 0,08777784 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03312778 0,08768274 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03312778 0,08758784 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03312778 0,08749315 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03312778 0,08739867 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03312778 0,08730439 GO:0055081|anion homeostasis, ! viral infectious cycle GO:0019058 104 51 1,000 0,03323361 0,0874889 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03323361 0,08739473 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,03323361 0,08730076 ! positive regulation of binding GO:0051099 88 52 1,000 0,03443806 0,09036755 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03443806 0,09027059 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03443806 0,09017383 ! amino acid activation GO:0043038 98 52 1,000 0,03443806 0,09007729 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! vesicle organization GO:0016050 127 53 1,000 0,03565932 0,09317189 ! cartilage development GO:0051216 99 53 1,000 0,03565932 0,09307235 ! synapse organization GO:0050808 102 53 1,000 0,03565932 0,09297302 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03689715 0,0960978 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,03689715 0,09599546 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,03689715 0,09589334 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,03689715 0,09579143 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,03689715 0,09568974 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03815134 0,09883745 ! cell recognition GO:0008037 98 55 1,000 0,03815134 0,09873275 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03815134 0,09862827 ! cell maturation GO:0048469 107 55 1,000 0,03815134 0,09852401 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03815134 0,09841998 ! tRNA transcription GO:0009304 17 7 0,000 0,03854192 0,09932268 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03854192 0,09921802 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03854192 0,09911358 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03854192 0,09900936 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03854192 0,09890536 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03854192 0,09880157 ! sleep GO:0030431 16 7 0,000 0,03854192 0,09869801 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03854192 0,09859466 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03854192 0,09849153 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03854192 0,09838861 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03854192 0,09828591 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03854192 0,09818342 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03854192 0,09808115 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03854192 0,09797908 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03854192 0,09787723 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03854192 0,0977756 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03854192 0,09767417 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03854192 0,09757295 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03854192 0,09747195 ! glycolipid transport GO:0046836 11 7 0,000 0,03854192 0,09737115 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03854192 0,09727056 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03854192 0,09717018 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03854192 0,09707 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03854192 0,09697003 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03854192 0,09687027 ! pericardium development GO:0060039 16 7 0,000 0,03854192 0,09677071 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03854192 0,09667136 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03854192 0,09657221 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03854192 0,09647326 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03854192 0,09637451 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03854192 0,09627597 ! lipoprotein transport GO:0042953 14 7 0,000 0,03854192 0,09617763 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03854192 0,09607949 ! rhythmic behavior GO:0007622 17 7 0,000 0,03854192 0,09598155 ! neuron remodeling GO:0016322 16 7 0,000 0,03854192 0,09588381 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03854192 0,09578627 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03854192 0,09568892 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03854192 0,09559178 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03854192 0,09549483 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03854192 0,09539807 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03854192 0,09530152 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03854192 0,09520516 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03854192 0,09510899 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03854192 0,09501302 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03854192 0,09491724 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03854192 0,09482165 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03854192 0,09472626 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03854192 0,09463106 ! spinal cord patterning GO:0021511 14 7 0,000 0,03854192 0,09453604 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03854192 0,09444122 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03854192 0,09434659 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03854192 0,09425215 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03854192 0,0941579 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03854192 0,09406384 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03854192 0,09396996 ! ovulation GO:0030728 10 7 0,000 0,03854192 0,09387627 ! adenohypophysis development GO:0021984 11 7 0,000 0,03854192 0,09378277 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03854192 0,09368945 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03854192 0,09359632 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03854192 0,09350338 ! microtubule nucleation GO:0007020 21 7 0,000 0,03854192 0,09341061 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03854192 0,09331804 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03854192 0,09322564 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03854192 0,09313343 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03854192 0,0930414 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03854192 0,09294956 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03854192 0,09285789 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03854192 0,0927664 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03854192 0,0926751 ! galactose metabolic process GO:0006012 13 7 0,000 0,03854192 0,09258397 ! vesicle fusion GO:0006906 20 7 0,000 0,03854192 0,09249303 ! response to dietary excess GO:0002021 8 7 0,000 0,03854192 0,09240226 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03854192 0,09231167 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03854192 0,09222125 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03854192 0,09213102 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03854192 0,09204096 ! organ growth GO:0035265 15 7 0,000 0,03854192 0,09195107 ! nucleoside transport GO:0015858 11 7 0,000 0,03854192 0,09186137 ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03854192 0,09177183 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03854192 0,09168247 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03854192 0,09159329 ! parturition GO:0007567 16 7 0,000 0,03854192 0,09150428 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03854192 0,09141544 ! rRNA modification GO:0000154 14 7 0,000 0,03854192 0,09132677 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03854192 0,09123828 ! spindle checkpoint GO:0031577 16 7 0,000 0,03854192 0,09114995 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03854192 0,0910618 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03854192 0,09097382 ! monocyte differentiation GO:0030224 16 7 0,000 0,03854192 0,090886 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03854192 0,09079836 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03854192 0,09071089 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03854192 0,09062358 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03854192 0,09053644 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03854192 0,09044947 ! fibrinolysis GO:0042730 11 7 0,000 0,03854192 0,09036267 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03854192 0,09027603 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03854192 0,09018956 ! eating behavior GO:0042755 8 7 0,000 0,03854192 0,09010325 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03854192 0,09001711 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03854192 0,08993114 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03854192 0,08984532 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03854192 0,08975968 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03854192 0,08967419 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03854192 0,08958887 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03854192 0,08950371 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03854192 0,08941871 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03854192 0,08933387 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03854192 0,08924919 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03854192 0,08916468 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03854192 0,08908032 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03854192 0,08899612 ! histone ubiquitination GO:0016574 9 7 0,000 0,03854192 0,08891209 ! regulation of meiosis GO:0040020 12 7 0,000 0,03854192 0,08882821 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03854192 0,08874449 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03854192 0,08866092 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03854192 0,08857752 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03854192 0,08849427 ! transcription termination GO:0006353 14 7 0,000 0,03854192 0,08841117 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03854192 0,08832824 ! anaphase GO:0051322 18 7 0,000 0,03854192 0,08824545 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03854192 0,08816283 ! axonal fasciculation GO:0007413 19 7 0,000 0,03854192 0,08808036 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03854192 0,08799804 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03854192 0,08791587 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03854192 0,08783386 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03854192 0,087752 ! diuresis GO:0030146 12 7 0,000 0,03854192 0,0876703 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03854192 0,08758874 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03854192 0,08750734 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03854192 0,08742609 ! antibiotic transport GO:0042891 9 7 0,000 0,03854192 0,08734499 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03854192 0,08726404 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03854192 0,08718324 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03854192 0,08710259 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03854192 0,08702209 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03854192 0,08694174 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03854192 0,08686153 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03854192 0,08678147 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03854192 0,08670157 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03854192 0,0866218 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03854192 0,08654219 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03854192 0,08646272 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03854192 0,08638339 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03854192 0,08630422 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03854192 0,08622518 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03854192 0,08614629 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03854192 0,08606755 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03854192 0,08598895 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03854192 0,08591049 ! muscle adaptation GO:0043500 13 7 0,000 0,03854192 0,08583218 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03854192 0,08575401 ! retina homeostasis GO:0001895 12 7 0,000 0,03854192 0,08567598 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03854192 0,08559809 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03854192 0,08552035 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03854192 0,08544274 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03854192 0,08536528 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03942166 0,0872347 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03942166 0,08715576 ! muscle fiber development GO:0048747 131 57 1,000 0,0407079 0,08991808 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0407079 0,08983685 ! heart morphogenesis GO:0003007 105 57 1,000 0,0407079 0,08975577 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,04200984 0,09254286 ! aging GO:0007568 112 58 1,000 0,04200984 0,09245949 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,04200984 0,09237627 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,04200984 0,09229319 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04200984 0,09221027 ! maintenance of location GO:0051235 124 58 1,000 0,04200984 0,0921275 ! nuclear export GO:0051168 110 59 1,000 0,04332726 0,09493139 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04392589 0,09615676 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04392589 0,09607067 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04392589 0,09598474 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04392589 0,09589896 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04392589 0,09581334 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04392589 0,09572787 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04392589 0,09564255 ! male meiosis GO:0007140 9 8 0,000 0,04392589 0,09555738 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04392589 0,09547237 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04392589 0,0953875 GO:0046463|acylglycerol biosynthetic process, ! response to zinc ion GO:0010043 12 8 0,000 0,04392589 0,09530279 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04392589 0,09521823 ! oligopeptide transport GO:0006857 16 8 0,000 0,04392589 0,09513381 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04392589 0,09504955 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04392589 0,09496543 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04392589 0,09488147 ! signal peptide processing GO:0006465 12 8 0,000 0,04392589 0,09479765 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04392589 0,09471398 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04392589 0,09463046 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04392589 0,09454708 ! succinate metabolic process GO:0006105 17 8 0,000 0,04392589 0,09446386 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04392589 0,09438077 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04392589 0,09429784 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04392589 0,09421505 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04392589 0,0941324 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04392589 0,0940499 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04392589 0,09396755 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04392589 0,09388534 ! reflex GO:0060004 17 8 0,000 0,04392589 0,09380327 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04392589 0,09372134 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04392589 0,09363956 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04392589 0,09355792 ! pigment granule organization GO:0048753 17 8 0,000 0,04392589 0,09347643 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04392589 0,09339507 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04392589 0,09331386 ! histidine catabolic process GO:0006548 10 8 0,000 0,04392589 0,09323279 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04392589 0,09315186 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04392589 0,09307107 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04392589 0,09299042 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04392589 0,0929099 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04392589 0,09282953 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04392589 0,0927493 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04392589 0,09266921 ! macrophage activation GO:0042116 13 8 0,000 0,04392589 0,09258925 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04392589 0,09250943 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04392589 0,09242975 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04392589 0,09235021 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04392589 0,0922708 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04392589 0,09219153 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04392589 0,09211239 ! osteoblast development GO:0002076 17 8 0,000 0,04392589 0,0920334 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04392589 0,09195453 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04392589 0,0918758 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04392589 0,09179721 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04392589 0,09171875 ! response to UV-B GO:0010224 17 8 0,000 0,04392589 0,09164043 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04392589 0,09156224 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04392589 0,09148418 ! intermediate filament organization GO:0045109 12 8 0,000 0,04392589 0,09140625 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04392589 0,09132846 ! cellular extravasation GO:0045123 13 8 0,000 0,04392589 0,0912508 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04392589 0,09117327 ! response to antibiotic GO:0046677 11 8 0,000 0,04392589 0,09109587 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04392589 0,09101861 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04392589 0,09094147 ! DNA topological change GO:0006265 12 8 0,000 0,04392589 0,09086447 ! response to tropane GO:0014073 15 8 0,000 0,04392589 0,0907876 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04392589 0,09071085 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04392589 0,09063424 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04392589 0,09055776 ! mast cell activation GO:0045576 14 8 0,000 0,04392589 0,0904814 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04392589 0,09040517 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04392589 0,09032907 ! gas homeostasis GO:0033483 14 8 0,000 0,04392589 0,0902531 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04392589 0,09017726 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04392589 0,09010154 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04392589 0,09002596 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04392589 0,08995049 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04392589 0,08987516 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04392589 0,08979995 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04392589 0,08972487 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04392589 0,08964991 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04392589 0,08957507 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04392589 0,08950037 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04392589 0,08942578 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04392589 0,08935132 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04392589 0,08927699 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04392589 0,08920278 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04392589 0,08912869 ! hormone catabolic process GO:0042447 17 8 0,000 0,04392589 0,08905472 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04392589 0,08898088 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04392589 0,08890716 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04392589 0,08883356 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04392589 0,08876008 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04392589 0,08868673 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04392589 0,08861349 ! adult feeding behavior GO:0008343 10 8 0,000 0,04392589 0,08854038 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04392589 0,08846739 ! ATP catabolic process GO:0006200 11 8 0,000 0,04392589 0,08839451 ! blastocyst growth GO:0001832 19 8 0,000 0,04392589 0,08832176 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04392589 0,08824913 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04392589 0,08817661 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04392589 0,08810422 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04392589 0,08803194 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04392589 0,08795979 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04392589 0,08788775 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04392589 0,08781583 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04392589 0,08774402 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04392589 0,08767234 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04392589 0,08760077 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04392589 0,08752931 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04392589 0,08745798 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04392589 0,08738676 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04392589 0,08731565 ! protein prenylation GO:0018342 21 8 0,000 0,04392589 0,08724467 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04392589 0,08717379 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04392589 0,08710304 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04392589 0,08703239 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,04465996 0,08841514 ! lipid modification GO:0030258 112 60 1,000 0,04465996 0,08834355 ! adult behavior GO:0030534 104 60 1,000 0,04465996 0,08827208 ! regulation of heart contraction GO:0008016 123 61 1,000 0,04600773 0,09086247 ! camera-type eye development GO:0043010 126 61 1,000 0,04600773 0,09078907 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,04737035 0,09340254 ! regulation of mitosis GO:0007088 112 63 1,000 0,04874761 0,09604066 GO:0051783|regulation of nuclear division, ! axon extension GO:0048675 16 9 0,000 0,04927986 0,09701103 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04927986 0,09693293 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04927986 0,09685494 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04927986 0,09677708 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04927986 0,09669935 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04927986 0,09662174 ! reproductive behavior GO:0019098 22 9 0,000 0,04927986 0,09654426 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04927986 0,0964669 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04927986 0,09638967 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04927986 0,09631255 ! UTP metabolic process GO:0046051 10 9 0,000 0,04927986 0,09623557 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04927986 0,0961587 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04927986 0,09608196 ! regulation of histone modification GO:0031056 14 9 0,000 0,04927986 0,09600534 ! equilibrioception GO:0050957 20 9 0,000 0,04927986 0,09592884 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04927986 0,09585246 ! chemosensory behavior GO:0007635 21 9 0,000 0,04927986 0,09577621 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04927986 0,09570007 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04927986 0,09562406 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04927986 0,09554817 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04927986 0,0954724 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04927986 0,09539675 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04927986 0,09532121 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04927986 0,0952458 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04927986 0,09517051 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04927986 0,09509533 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04927986 0,09502028 ! protein targeting to ER GO:0045047 25 9 0,000 0,04927986 0,09494534 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04927986 0,09487052 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04927986 0,09479582 ! T cell selection GO:0045058 27 9 0,000 0,04927986 0,09472124 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04927986 0,09464677 ! glycine catabolic process GO:0006546 15 9 0,000 0,04927986 0,09457242 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04927986 0,09449819 ! endosome organization GO:0007032 20 9 0,000 0,04927986 0,09442407 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04927986 0,09435007 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04927986 0,09427619 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04927986 0,09420242 ! mannose metabolic process GO:0006013 13 9 0,000 0,04927986 0,09412877 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04927986 0,09405523 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04927986 0,09398181 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04927986 0,0939085 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04927986 0,0938353 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04927986 0,09376222 ! retinol metabolic process GO:0042572 20 9 0,000 0,04927986 0,09368926 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04927986 0,0936164 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04927986 0,09354366 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04927986 0,09347104 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04927986 0,09339852 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04927986 0,09332612 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04927986 0,09325383 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04927986 0,09318165 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04927986 0,09310958 ! response to amine stimulus GO:0014075 13 9 0,000 0,04927986 0,09303763 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04927986 0,09296579 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04927986 0,09289405 ! erythrocyte development GO:0048821 17 9 0,000 0,04927986 0,09282243 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04927986 0,09275092 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04927986 0,09267952 ! renal water homeostasis GO:0003091 15 9 0,000 0,04927986 0,09260823 ! postreplication repair GO:0006301 25 9 0,000 0,04927986 0,09253704 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04927986 0,09246597 ! icosanoid secretion GO:0032309 15 9 0,000 0,04927986 0,09239501 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04927986 0,09232415 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04927986 0,0922534 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04927986 0,09218277 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04927986 0,09211224 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04927986 0,09204181 ! sterol catabolic process GO:0016127 14 9 0,000 0,04927986 0,0919715 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04927986 0,09190129 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04927986 0,09183119 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04927986 0,0917612 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04927986 0,09169131 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04927986 0,09162153 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04927986 0,09155186 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04927986 0,09148229 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04927986 0,09141283 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04927986 0,09134347 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04927986 0,09127422 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04927986 0,09120507 ! pigment granule transport GO:0051904 17 9 0,000 0,04927986 0,09113603 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04927986 0,09106709 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04927986 0,09099826 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04927986 0,09092953 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04927986 0,0908609 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04927986 0,09079238 ! mitochondrion localization GO:0051646 18 9 0,000 0,04927986 0,09072396 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,05013932 0,09223672 ! ear development GO:0043583 114 66 1,000 0,05296527 0,09736204 ! activation of MAPK activity GO:0000187 124 67 1,000 0,0543991 0,09992255 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,0543991 0,09984748 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,0543991 0,09977252 ! secondary metabolic process GO:0019748 125 67 1,000 0,0543991 0,09969767 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,054604 0,09999818 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,054604 0,09992327 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,054604 0,09984848 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,054604 0,0997738 ! associative learning GO:0008306 21 10 0,000 0,054604 0,09969923 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,054604 0,09962477 ! phosphate transport GO:0006817 24 10 0,000 0,054604 0,09955042 ! cell volume homeostasis GO:0006884 17 10 0,000 0,054604 0,09947619 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,054604 0,09940206 ! CTP metabolic process GO:0046036 11 10 0,000 0,054604 0,09932805 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,054604 0,09925414 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,054604 0,09918035 ! GTP metabolic process GO:0046039 11 10 0,000 0,054604 0,09910666 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,054604 0,09903309 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,054604 0,09895962 ! social behavior GO:0035176 29 10 0,000 0,054604 0,09888626 ! smoothened signaling pathway GO:0007224 18 10 0,000 0,054604 0,09881301 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,054604 0,09873987 ! androgen metabolic process GO:0008209 17 10 0,000 0,054604 0,09866684 ! phospholipid efflux GO:0033700 19 10 0,000 0,054604 0,09859391 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,054604 0,0985211 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,054604 0,09844839 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,054604 0,09837579 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,054604 0,09830329 ! pathogenesis GO:0009405 17 10 0,000 0,054604 0,0982309 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,054604 0,09815862 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,054604 0,09808645 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,054604 0,09801438 ! endoderm development GO:0007492 18 10 0,000 0,054604 0,09794241 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,054604 0,09787056 ! arginine catabolic process GO:0006527 17 10 0,000 0,054604 0,0977988 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,054604 0,09772716 ! proline metabolic process GO:0006560 13 10 0,000 0,054604 0,09765561 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,054604 0,09758417 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,054604 0,09751284 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 34 10 0,000 0,054604 0,09744161 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,054604 0,09737049 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,054604 0,09729947 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,054604 0,09722855 ! B cell proliferation GO:0042100 19 10 0,000 0,054604 0,09715773 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,054604 0,09708702 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,054604 0,09701641 ! multicellular organism growth GO:0035264 19 10 0,000 0,054604 0,09694591 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,054604 0,0968755 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,054604 0,0968052 ! ruffle organization GO:0031529 17 10 0,000 0,054604 0,096735 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,054604 0,0966649 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,054604 0,09659491 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,054604 0,09652501 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,054604 0,09645522 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,054604 0,09638553 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,054604 0,09631593 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,054604 0,09624644 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,054604 0,09617705 ! segment specification GO:0007379 15 10 0,000 0,054604 0,09610776 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,054604 0,09603857 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,054604 0,09596947 ! blastoderm segmentation GO:0007350 19 10 0,000 0,054604 0,09590048 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,054604 0,09583159 ! response to dsRNA GO:0043331 23 10 0,000 0,054604 0,09576279 ! DNA ligation GO:0006266 18 10 0,000 0,054604 0,09569409 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,054604 0,0956255 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,054604 0,095557 ! melanosome localization GO:0032400 16 10 0,000 0,054604 0,09548859 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,054604 0,09542029 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,054604 0,09535208 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,054604 0,09528398 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,054604 0,09521596 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,054604 0,09514805 ! induction of an organ GO:0001759 17 10 0,000 0,054604 0,09508023 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,054604 0,09501251 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,054604 0,09494489 ! protein sumoylation GO:0016925 17 10 0,000 0,054604 0,09487736 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,054604 0,09480993 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,054604 0,09474259 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,054604 0,09467535 ! salivary gland development GO:0007431 28 10 0,000 0,054604 0,0946082 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,054604 0,09454115 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,054604 0,0944742 ! midbrain development GO:0030901 14 10 0,000 0,054604 0,09440734 ! musculoskeletal movement GO:0050881 16 10 0,000 0,054604 0,09434057 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,054604 0,0942739 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,054604 0,09420732 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,054604 0,09414084 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,054604 0,09407445 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,054604 0,09400815 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,054604 0,09394195 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,054604 0,09387584 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,054604 0,09380982 ! detection of calcium ion GO:0005513 24 10 0,000 0,054604 0,0937439 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,054604 0,09367807 ! blastocyst formation GO:0001825 18 10 0,000 0,054604 0,09361233 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,054604 0,09354668 ! cerebellar cortex development GO:0021695 16 10 0,000 0,054604 0,09348113 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,054604 0,09341566 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,054604 0,09335029 ! response to nicotine GO:0035094 20 10 0,000 0,054604 0,09328501 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,054604 0,09321982 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05584657 0,09527456 ! extracellular matrix organization GO:0030198 146 68 1,000 0,05584657 0,09520808 ! detection of external stimulus GO:0009581 102 68 1,000 0,05584657 0,09514168 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05584657 0,09507538 ! adaptive immune response GO:0002250 126 68 1,000 0,05584657 0,09500917 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,05584657 0,09494306 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,05730749 0,09735897 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,05730749 0,09729131 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,05730749 0,09722375 ! developmental maturation GO:0021700 128 69 1,000 0,05730749 0,09715628 ! respiratory burst GO:0045730 17 11 0,000 0,05989847 0,10147848 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05989847 0,10140815 ! neuron fate specification GO:0048665 18 11 0,000 0,05989847 0,10133793 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05989847 0,1012678 ! thyroid gland development GO:0030878 26 11 0,000 0,05989847 0,10119776 ! synapsis GO:0007129 14 11 0,000 0,05989847 0,10112783 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05989847 0,10105799 ! response to pain GO:0048265 27 11 0,000 0,05989847 0,10098824 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05989847 0,1009186 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05989847 0,10084905 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,05989847 0,10077959 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05989847 0,10071023 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05989847 0,10064097 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05989847 0,1005718 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05989847 0,10050272 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05989847 0,10043374 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05989847 0,10036486 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05989847 0,10029607 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05989847 0,10022737 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05989847 0,10015877 ! UV protection GO:0009650 20 11 0,000 0,05989847 0,10009026 ! adult heart development GO:0007512 16 11 0,000 0,05989847 0,10002185 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05989847 0,09995353 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05989847 0,0998853 ! macroautophagy GO:0016236 19 11 0,000 0,05989847 0,09981717 ! temperature homeostasis GO:0001659 18 11 0,000 0,05989847 0,09974912 ! behavioral fear response GO:0001662 27 11 0,000 0,05989847 0,09968117 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05989847 0,09961332 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05989847 0,09954555 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05989847 0,09947788 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05989847 0,0994103 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05989847 0,09934281 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05989847 0,09927542 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05989847 0,09920811 ! regulation of organ growth GO:0046620 14 11 0,000 0,05989847 0,0991409 ! pigment granule localization GO:0051875 20 11 0,000 0,05989847 0,09907377 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05989847 0,09900674 ! vasoconstriction GO:0042310 20 11 0,000 0,05989847 0,0989398 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05989847 0,09887295 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05989847 0,09880619 ! embryonic axis specification GO:0000578 19 11 0,000 0,05989847 0,09873952 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05989847 0,09867294 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05989847 0,09860645 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05989847 0,09854004 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05989847 0,09847373 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05989847 0,09840751 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05989847 0,09834137 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05989847 0,09827533 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05989847 0,09820937 ! nucleosome positioning GO:0016584 15 11 0,000 0,05989847 0,0981435 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05989847 0,09807772 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05989847 0,09801203 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05989847 0,09794643 ! apical protein localization GO:0045176 18 11 0,000 0,05989847 0,09788091 ! acid secretion GO:0046717 20 11 0,000 0,05989847 0,09781548 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05989847 0,09775014 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05989847 0,09768489 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05989847 0,09761972 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05989847 0,09755464 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05989847 0,09748965 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05989847 0,09742474 ! cholesterol efflux GO:0033344 21 11 0,000 0,05989847 0,09735992 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05989847 0,09729519 ! oocyte development GO:0048599 20 11 0,000 0,05989847 0,09723054 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05989847 0,09716598 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05989847 0,0971015 ! embryonic gut development GO:0048566 19 11 0,000 0,05989847 0,09703711 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05989847 0,09697281 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05989847 0,09690859 ! activation of innate immune response GO:0002218 16 11 0,000 0,05989847 0,09684445 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05989847 0,0967804 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05989847 0,09671643 ! lysogeny GO:0030069 22 11 0,000 0,05989847 0,09665255 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05989847 0,09658876 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05989847 0,09652504 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05989847 0,09646141 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,06026889 0,09699401 ! appendage morphogenesis GO:0035107 150 72 1,000 0,06176899 0,09934276 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 1,000 0,06176899 0,0992774 ! B cell activation GO:0042113 179 72 1,000 0,06176899 0,09921213 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,06176899 0,09914695 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,06176899 0,09908185 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,06176899 0,09901683 ! appendage development GO:0048736 151 73 1,000 0,06328177 0,10137533 GO:0060173|limb development, ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06516344 0,10432129 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06516344 0,10425297 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06516344 0,10418474 ! mating GO:0007618 17 12 0,000 0,06516344 0,1041166 ! protein complex disassembly GO:0043241 28 12 0,000 0,06516344 0,10404855 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 29 12 0,000 0,06516344 0,10398059 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06516344 0,10391272 ! T cell proliferation GO:0042098 32 12 0,000 0,06516344 0,10384494 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06516344 0,10377724 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06516344 0,10370963 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06516344 0,10364211 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06516344 0,10357468 ! drug transport GO:0015893 16 12 0,000 0,06516344 0,10350734 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06516344 0,10344008 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06516344 0,10337291 ! focal adhesion formation GO:0048041 37 12 0,000 0,06516344 0,10330583 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06516344 0,10323884 ! lipid digestion GO:0044241 21 12 0,000 0,06516344 0,10317193 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06516344 0,10310511 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06516344 0,10303837 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06516344 0,10297173 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06516344 0,10290516 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06516344 0,10283869 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06516344 0,1027723 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06516344 0,10270599 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06516344 0,10263977 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06516344 0,10257364 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06516344 0,10250759 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06516344 0,10244163 ! fucose catabolic process GO:0019317 25 12 0,000 0,06516344 0,10237575 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06516344 0,10230995 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06516344 0,10224424 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06516344 0,10217862 ! zymogen activation GO:0031638 18 12 0,000 0,06516344 0,10211308 ! T cell homeostasis GO:0043029 28 12 0,000 0,06516344 0,10204762 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06516344 0,10198225 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06516344 0,10191696 ! oocyte differentiation GO:0009994 21 12 0,000 0,06516344 0,10185175 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06516344 0,10178663 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06516344 0,10172159 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06516344 0,10165663 ! defense response to fungus GO:0050832 15 12 0,000 0,06516344 0,10159176 ! developmental induction GO:0031128 22 12 0,000 0,06516344 0,10152697 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06516344 0,10146226 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06516344 0,10139764 ! response to cold GO:0009409 17 12 0,000 0,06516344 0,10133309 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06516344 0,10126863 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06516344 0,10120425 ! eye development GO:0001654 155 75 1,000 0,06634462 0,10297326 ! axon guidance GO:0007411 162 75 1,000 0,06634462 0,10290788 ! rhythmic process GO:0048511 142 75 1,000 0,06634462 0,10284259 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,06789433 0,10517808 ! amine catabolic process GO:0009310 136 77 1,000 0,06945597 0,10752911 ! neurotransmitter transport GO:0006836 142 77 1,000 0,06945597 0,10746101 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,06945597 0,10739299 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,06945597 0,10732507 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07039907 0,10871361 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07039907 0,10864494 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07039907 0,10857635 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07039907 0,10850785 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07039907 0,10843943 ! peroxisomal transport GO:0043574 28 13 0,000 0,07039907 0,1083711 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07039907 0,10830286 ! organelle fusion GO:0048284 36 13 0,000 0,07039907 0,1082347 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07039907 0,10816663 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07039907 0,10809864 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07039907 0,10803074 ! endocrine pancreas development GO:0031018 25 13 0,000 0,07039907 0,10796292 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,07039907 0,10789519 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07039907 0,10782755 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07039907 0,10775999 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07039907 0,10769251 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07039907 0,10762512 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07039907 0,10755781 ! methionine metabolic process GO:0006555 31 13 0,000 0,07039907 0,10749059 ! plasma membrane organization GO:0007009 27 13 0,000 0,07039907 0,10742345 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07039907 0,10735639 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07039907 0,10728942 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07039907 0,10722253 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07039907 0,10715572 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,07039907 0,107089 ! exocrine system development GO:0035272 34 13 0,000 0,07039907 0,10702236 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07039907 0,10695581 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07039907 0,10688933 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07039907 0,10682294 ! L-glutamate transport GO:0015813 30 13 0,000 0,07039907 0,10675663 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07039907 0,10669041 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07039907 0,10662426 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07039907 0,1065582 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07039907 0,10649222 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07039907 0,10642632 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07039907 0,10636051 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07039907 0,10629477 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07039907 0,10622911 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07039907 0,10616354 ! histone methylation GO:0016571 29 13 0,000 0,07039907 0,10609805 ! chromatin silencing GO:0006342 29 13 0,000 0,07039907 0,10603264 ! gland morphogenesis GO:0022612 31 13 0,000 0,07039907 0,10596731 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07039907 0,10590205 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07039907 0,10583688 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07039907 0,10577179 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07039907 0,10570678 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07039907 0,10564185 ! spleen development GO:0048536 24 13 0,000 0,07039907 0,105577 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,07039907 0,10551223 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07039907 0,10544754 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07039907 0,10538293 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07039907 0,10531839 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07039907 0,10525394 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07039907 0,10518956 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07039907 0,10512527 ! insulin secretion GO:0030073 24 13 0,000 0,07039907 0,10506105 ! acrosome reaction GO:0007340 19 13 0,000 0,07039907 0,10499691 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07039907 0,10493285 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07039907 0,10486886 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,07102937 0,1057433 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,07261435 0,10803707 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,07261435 0,10797131 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,07421074 0,11027788 ! rRNA transcription GO:0009303 28 14 0,000 0,07560553 0,11228225 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07560553 0,11221404 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07560553 0,11214591 ! water transport GO:0006833 21 14 0,000 0,07560553 0,11207786 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07560553 0,11200989 ! non-recombinational repair GO:0000726 29 14 0,000 0,07560553 0,11194201 GO:0006303|double-strand break repair via nonhomologous end joining, ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07560553 0,1118742 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07560553 0,11180648 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07560553 0,11173884 ! lipid localization GO:0010876 32 14 0,000 0,07560553 0,11167129 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07560553 0,11160381 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,07560553 0,11153642 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07560553 0,11146911 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07560553 0,11140187 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07560553 0,11133472 ! arginine metabolic process GO:0006525 21 14 0,000 0,07560553 0,11126766 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07560553 0,11120067 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07560553 0,11113376 ! regulation of heart rate GO:0002027 25 14 0,000 0,07560553 0,11106693 ! fear response GO:0042596 34 14 0,000 0,07560553 0,11100019 ! organic alcohol transport GO:0015850 29 14 0,000 0,07560553 0,11093352 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07560553 0,11086693 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07560553 0,11080043 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07560553 0,110734 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07560553 0,11066765 ! bone mineralization GO:0030282 18 14 0,000 0,07560553 0,11060138 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07560553 0,11053519 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07560553 0,11046908 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07560553 0,11040305 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07560553 0,1103371 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07560553 0,11027123 ! ribosome assembly GO:0042255 18 14 0,000 0,07560553 0,11020543 ! cerebellum development GO:0021549 23 14 0,000 0,07560553 0,11013972 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07560553 0,11007408 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07560553 0,11000852 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07560553 0,10994304 ! NADP metabolic process GO:0006739 24 14 0,000 0,07560553 0,10987764 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07560553 0,10981231 ! oxygen transport GO:0015671 22 14 0,000 0,07560553 0,10974706 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07560553 0,10968189 ! male genitalia development GO:0030539 26 14 0,000 0,07560553 0,1096168 ! regulation of axon extension GO:0030516 43 14 0,000 0,07560553 0,10955178 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07560553 0,10948685 ! muscle cell differentiation GO:0042692 178 81 1,000 0,07581835 0,10972999 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,07581835 0,10966503 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,07743702 0,11194002 ! protein import into nucleus GO:0006606 174 82 1,000 0,07743702 0,11187382 ! exocytosis GO:0006887 153 83 1,000 0,07906656 0,11416053 ! response to drug GO:0042493 149 83 1,000 0,07906656 0,1140931 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,07906656 0,11402575 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,07906656 0,11395847 ! regulation of ligase activity GO:0051340 147 84 1,000 0,08070682 0,11625398 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08078297 0,11629511 ! lactation GO:0007595 30 15 0,000 0,08078297 0,11622662 ! reproductive cellular process GO:0048610 22 15 0,000 0,08078297 0,11615821 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08078297 0,11608988 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08078297 0,11602163 ! superoxide anion generation GO:0042554 22 15 0,000 0,08078297 0,11595347 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08078297 0,11588538 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08078297 0,11581737 ! copper ion transport GO:0006825 22 15 0,000 0,08078297 0,11574944 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08078297 0,11568159 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08078297 0,11561382 ! sulfate transport GO:0008272 27 15 0,000 0,08078297 0,11554613 ! response to cAMP GO:0051591 25 15 0,000 0,08078297 0,11547852 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08078297 0,11541099 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08078297 0,11534354 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08078297 0,11527617 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08078297 0,11520887 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08078297 0,11514166 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08078297 0,11507452 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08078297 0,11500746 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08078297 0,11494048 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08078297 0,11487357 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08078297 0,11480675 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08078297 0,11474 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08078297 0,11467333 ! regulation of vasodilation GO:0042312 27 15 0,000 0,08078297 0,11460674 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,08078297 0,11454022 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08078297 0,11447378 ! water homeostasis GO:0030104 28 15 0,000 0,08078297 0,11440742 ! cofactor transport GO:0051181 30 15 0,000 0,08078297 0,11434113 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08078297 0,11427493 ! muscle maintenance GO:0046716 26 15 0,000 0,08078297 0,1142088 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08078297 0,11414274 ! intestinal absorption GO:0050892 31 15 0,000 0,08078297 0,11407676 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08078297 0,11401086 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08078297 0,11394503 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08078297 0,11387928 ! cell killing GO:0001906 32 15 0,000 0,08078297 0,11381361 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,08078297 0,11374801 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,08078297 0,11368249 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08078297 0,11361704 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08078297 0,11355167 ! actin filament polymerization GO:0030041 27 15 0,000 0,08078297 0,11348637 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08078297 0,11342115 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,08235761 0,11556557 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,08401878 0,11782887 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08593156 0,12044223 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08593156 0,12037316 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08593156 0,12030418 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08593156 0,12023528 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08593156 0,12016646 ! bone remodeling GO:0046849 28 16 0,000 0,08593156 0,12009771 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08593156 0,12002904 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08593156 0,11996046 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08593156 0,11989195 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08593156 0,11982352 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08593156 0,11975516 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08593156 0,11968689 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08593156 0,11961869 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08593156 0,11955057 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08593156 0,11948253 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08593156 0,11941456 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08593156 0,11934667 ! response to osmotic stress GO:0006970 27 16 0,000 0,08593156 0,11927886 ! lysosomal transport GO:0007041 31 16 0,000 0,08593156 0,11921113 ! fructose metabolic process GO:0006000 25 16 0,000 0,08593156 0,11914347 ! L-amino acid transport GO:0015807 33 16 0,000 0,08593156 0,11907589 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08593156 0,11900839 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08593156 0,11894096 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08593156 0,11887361 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08593156 0,11880634 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08593156 0,11873914 ! axon cargo transport GO:0008088 46 16 0,000 0,08593156 0,11867202 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08593156 0,11860497 ! DNA replication initiation GO:0006270 28 16 0,000 0,08593156 0,118538 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08593156 0,11847111 ! tissue regeneration GO:0042246 27 16 0,000 0,08593156 0,11840429 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08593156 0,11833754 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08593156 0,11827087 ! biomineral formation GO:0031214 22 16 0,000 0,08593156 0,11820428 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08593156 0,11813776 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08593156 0,11807132 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08593156 0,11800495 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08593156 0,11793865 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08593156 0,11787243 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08593156 0,11780628 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08593156 0,11774021 ! peptide hormone processing GO:0016486 27 16 0,000 0,08593156 0,11767421 ! amine biosynthetic process GO:0009309 146 88 1,000 0,08737157 0,11957913 ! protein localization in nucleus GO:0034504 192 89 1,000 0,08906286 0,12182562 ! regulation of neurological system process GO:0031644 175 89 1,000 0,08906286 0,12175745 ! response to unfolded protein GO:0006986 139 90 1,000 0,09076386 0,12401349 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,09076386 0,12394417 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,09105145 0,12426743 ! metencephalon development GO:0022037 32 17 0,000 0,09105145 0,12419805 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,09105145 0,12412874 ! endothelial cell migration GO:0043542 31 17 0,000 0,09105145 0,12405951 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09105145 0,12399036 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09105145 0,12392128 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,09105145 0,12385228 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09105145 0,12378336 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09105145 0,12371452 ! myoblast differentiation GO:0045445 50 17 0,000 0,09105145 0,12364575 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,09105145 0,12357706 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09105145 0,12350844 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09105145 0,1234399 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09105145 0,12337144 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09105145 0,12330305 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,09105145 0,12323474 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,09105145 0,1231665 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09105145 0,12309834 ! regulation of protein binding GO:0043393 33 17 0,000 0,09105145 0,12303026 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09105145 0,12296225 ! genitalia development GO:0048806 32 17 0,000 0,09105145 0,12289431 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09105145 0,12282645 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09105145 0,12275867 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09105145 0,12269096 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,09105145 0,12262332 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09105145 0,12255576 ! steroid catabolic process GO:0006706 34 17 0,000 0,09105145 0,12248827 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09105145 0,12242086 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,09105145 0,12235352 ! gas transport GO:0015669 26 17 0,000 0,09105145 0,12228626 ! organic cation transport GO:0015695 32 17 0,000 0,09105145 0,12221907 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,09105145 0,12215195 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,09105145 0,12208491 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,09592357 0,12854706 GO:0010498|proteasomal protein catabolic process, ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09614281 0,12877023 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09614281 0,12869967 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09614281 0,12862919 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09614281 0,12855878 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09614281 0,12848845 ! adult walking behavior GO:0007628 36 18 0,000 0,09614281 0,1284182 ! heart looping GO:0001947 34 18 0,000 0,09614281 0,12834803 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09614281 0,12827793 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09614281 0,12820791 ! centrosome cycle GO:0007098 26 18 0,000 0,09614281 0,12813797 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09614281 0,1280681 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09614281 0,12799831 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,09614281 0,12792859 ! glycine metabolic process GO:0006544 30 18 0,000 0,09614281 0,12785895 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09614281 0,12778939 ! response to retinoic acid GO:0032526 31 18 0,000 0,09614281 0,1277199 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,09614281 0,12765049 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09614281 0,12758115 ! DNA integration GO:0015074 32 18 0,000 0,09614281 0,12751189 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09614281 0,1274427 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09614281 0,12737359 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09614281 0,12730455 ! neural crest cell migration GO:0001755 41 18 0,000 0,09614281 0,12723559 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09614281 0,1271667 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09614281 0,12709789 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09614281 0,12702915 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09614281 0,12696048 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09614281 0,12689189 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09614281 0,12682338 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09614281 0,12675494 ! detection of bacterium GO:0016045 22 18 0,000 0,09614281 0,12668657 ! defense response to virus GO:0051607 43 18 0,000 0,09614281 0,12661827 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09614281 0,12655005 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09614281 0,1264819 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,09766185 0,12841114 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,09940905 0,13063814 ! sex differentiation GO:0007548 171 96 1,000 0,10116503 0,13287428 ! response to protein stimulus GO:0051789 158 96 1,000 0,10116503 0,13280288 ! regulation of T cell activation GO:0050863 175 96 1,000 0,10116503 0,13273156 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,1012058 0,13271378 ! positive regulation of translation GO:0045727 31 19 0,000 0,1012058 0,13264258 ! negative regulation of defense response GO:0031348 27 19 0,000 0,1012058 0,13257146 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,1012058 0,13250041 ! neuron maturation GO:0042551 46 19 0,000 0,1012058 0,13242944 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,1012058 0,13235855 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,1012058 0,13228773 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,1012058 0,13221699 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,1012058 0,13214632 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,1012058 0,13207573 ! inositol metabolic process GO:0006020 33 19 0,000 0,1012058 0,13200521 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,1012058 0,13193477 ! memory GO:0007613 34 19 0,000 0,1012058 0,13186441 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,1012058 0,13179412 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,1012058 0,1317239 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,1012058 0,13165376 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,1012058 0,1315837 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,1012058 0,13151371 ! response to vitamin A GO:0033189 32 19 0,000 0,1012058 0,13144379 ! heme metabolic process GO:0042168 40 19 0,000 0,1012058 0,13137395 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,1012058 0,13130418 ! response to fungus GO:0009620 26 19 0,000 0,1012058 0,13123448 ! peptide cross-linking GO:0018149 39 19 0,000 0,1012058 0,13116486 ! heart process GO:0003015 32 19 0,000 0,1012058 0,13109532 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,1012058 0,13102584 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,1012058 0,13095644 ! cellular pigmentation GO:0033059 37 19 0,000 0,1012058 0,13088712 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,1012058 0,13081787 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,1012058 0,13074869 ! vitamin transport GO:0051180 31 19 0,000 0,1012058 0,13067958 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,1012058 0,13061055 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,1012058 0,13054159 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,1012058 0,1304727 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,1012058 0,13040389 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,1012058 0,13033514 ! cilium assembly GO:0042384 38 19 0,000 0,1012058 0,13026647 ! peptide hormone secretion GO:0030072 32 19 0,000 0,1012058 0,13019788 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,10292963 0,13234583 ! protein secretion GO:0009306 45 20 0,000 0,10624056 0,13653114 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10624056 0,13645936 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10624056 0,13638765 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10624056 0,13631602 ! skin development GO:0043588 42 20 0,000 0,10624056 0,13624446 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10624056 0,13617298 ! response to vitamin GO:0033273 36 20 0,000 0,10624056 0,13610157 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10624056 0,13603024 ! bile acid metabolic process GO:0008206 34 20 0,000 0,10624056 0,13595898 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10624056 0,1358878 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,10624056 0,13581669 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10624056 0,13574566 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10624056 0,1356747 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 0,10624056 0,13560381 ! body fluid secretion GO:0007589 33 20 0,000 0,10624056 0,135533 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10624056 0,13546226 ! peptide secretion GO:0002790 38 20 0,000 0,10624056 0,1353916 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10624056 0,13532101 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,10624056 0,13525049 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10624056 0,13518005 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10624056 0,13510968 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,10624056 0,13503939 ! cell-cell junction organization GO:0045216 43 20 0,000 0,10624056 0,13496916 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,10624056 0,13489901 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10624056 0,13482893 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,10624056 0,13475893 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,10624056 0,134689 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10624056 0,13461914 ! regulation of glucose import GO:0046324 30 20 0,000 0,10624056 0,13454935 GO:0010827|regulation of glucose transport, ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10624056 0,13447964 ! negative regulation of translation GO:0017148 32 20 0,000 0,10624056 0,13440999 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10624056 0,13434042 ! hormone metabolic process GO:0042445 171 100 1,000 0,10827366 0,13684044 ! regulation of cell killing GO:0031341 46 21 0,000 0,11124727 0,14052589 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,11124727 0,14045327 ! hormone secretion GO:0046879 39 21 0,000 0,11124727 0,14038072 ! cAMP metabolic process GO:0046058 41 21 0,000 0,11124727 0,14030825 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,11124727 0,14023585 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,11124727 0,14016352 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,11124727 0,14009128 ! ovarian follicle development GO:0001541 39 21 0,000 0,11124727 0,1400191 ! smooth muscle contraction GO:0006939 48 21 0,000 0,11124727 0,139947 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,11124727 0,13987497 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,11124727 0,13980302 ! plasma membrane fusion GO:0045026 33 21 0,000 0,11124727 0,13973114 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,11124727 0,13965934 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,11124727 0,13958761 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,11124727 0,13951595 ! sensory perception of pain GO:0019233 33 21 0,000 0,11124727 0,13944437 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,11124727 0,13937286 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,11124727 0,13930142 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,11124727 0,13923006 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,11124727 0,13915877 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,11124727 0,13908755 ! collagen catabolic process GO:0030574 29 21 0,000 0,11124727 0,13901641 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,11124727 0,13894533 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,11124727 0,13887434 ! actin filament-based movement GO:0030048 47 21 0,000 0,11124727 0,13880341 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11622606 0,14494144 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11622606 0,14486749 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11622606 0,14479361 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11622606 0,14471981 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11622606 0,14464609 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11622606 0,14457244 ! microtubule-based transport GO:0010970 59 22 0,000 0,11622606 0,14449887 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11622606 0,14442537 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,11622606 0,14435194 ! vacuolar transport GO:0007034 41 22 0,000 0,11622606 0,14427859 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11622606 0,14420532 ! fucose metabolic process GO:0006004 44 22 0,000 0,11622606 0,14413212 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11622606 0,14405899 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11622606 0,14398594 ! ureteric bud development GO:0001657 50 22 0,000 0,11622606 0,14391296 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11622606 0,14384006 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,11622606 0,14376723 ! cytolysis GO:0019835 27 22 0,000 0,11622606 0,14369447 ! renal system process GO:0003014 42 22 0,000 0,11622606 0,14362179 ! vasodilation GO:0042311 40 22 0,000 0,11622606 0,14354918 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11622606 0,14347664 ! G1 phase GO:0051318 44 22 0,000 0,11622606 0,14340418 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11622606 0,14333179 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11622606 0,14325947 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11622606 0,14318723 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11622606 0,14311506 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11622606 0,14304296 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11622606 0,14297093 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11622606 0,14289898 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11622606 0,1428271 ! gut development GO:0048565 44 22 0,000 0,11622606 0,14275529 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11622606 0,14268356 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11622606 0,14261189 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,12117711 0,14861229 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,12117711 0,14853772 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,12117711 0,14846323 ! gluconeogenesis GO:0006094 38 23 0,000 0,12117711 0,14838881 ! glycerol metabolic process GO:0006071 40 23 0,000 0,12117711 0,14831447 ! viral genome replication GO:0019079 44 23 0,000 0,12117711 0,1482402 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,12117711 0,148166 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,12117711 0,14809188 ! regeneration GO:0031099 42 23 0,000 0,12117711 0,14801784 ! axis specification GO:0009798 43 23 0,000 0,12117711 0,14794387 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,12117711 0,14786997 ! response to ethanol GO:0045471 47 23 0,000 0,12117711 0,14779614 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,12117711 0,14772239 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,12117711 0,14764872 ! peroxisome organization GO:0007031 43 23 0,000 0,12117711 0,14757511 ! lysosome organization GO:0007040 47 23 0,000 0,12117711 0,14750158 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,12117711 0,14742813 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,12117711 0,14735474 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,12117711 0,14728143 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,12117711 0,14720819 ! DNA modification GO:0006304 36 23 0,000 0,12117711 0,14713503 ! fatty acid transport GO:0015908 47 23 0,000 0,12117711 0,14706194 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,12117711 0,14698892 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,12117711 0,14691597 ! hormone transport GO:0009914 41 23 0,000 0,12117711 0,14684309 ! cell-cell recognition GO:0009988 28 23 0,000 0,12117711 0,14677029 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,12117711 0,14669756 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,12117711 0,1466249 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,12117711 0,14655232 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12610056 0,1524313 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12610056 0,15235591 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12610056 0,1522806 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12610056 0,15220536 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12610056 0,1521302 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12610056 0,15205511 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,12610056 0,1519801 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,12610056 0,15190516 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,12610056 0,15183029 ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,12610056 0,1517555 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12610056 0,15168078 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,12610056 0,15160613 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,12610056 0,15153156 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12610056 0,15145706 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12610056 0,15138263 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12610056 0,15130828 ! membrane depolarization GO:0051899 45 24 0,000 0,12610056 0,151234 ! oogenesis GO:0048477 44 24 0,000 0,12610056 0,15115979 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,12610056 0,15108566 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12610056 0,1510116 ! platelet activation GO:0030168 41 24 0,000 0,12610056 0,15093761 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12610056 0,15086369 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12610056 0,15078985 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12610056 0,15071608 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12610056 0,15064238 ! regulation of amine transport GO:0051952 41 24 0,000 0,12610056 0,15056875 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,12610056 0,15049519 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,13099656 0,15626201 ! leukocyte adhesion GO:0007159 55 25 0,000 0,13099656 0,15618574 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,13099656 0,15610956 ! phototransduction GO:0007602 37 25 0,000 0,13099656 0,15603344 ! keratinization GO:0031424 37 25 0,000 0,13099656 0,1559574 ! vacuole organization GO:0007033 49 25 0,000 0,13099656 0,15588144 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,13099656 0,15580555 ! chromosome condensation GO:0030261 48 25 0,000 0,13099656 0,15572973 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,13099656 0,15565398 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,13099656 0,15557831 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,13099656 0,15550272 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,13099656 0,15542719 ! immunoglobulin production GO:0002377 62 25 0,000 0,13099656 0,15535174 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,13099656 0,15527637 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,13099656 0,15520106 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,13099656 0,15512583 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13586527 0,1608134 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13586527 0,16073552 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13586527 0,16065772 ! molting cycle process GO:0022404 52 26 0,000 0,13586527 0,16057999 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13586527 0,16050234 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,13586527 0,16042477 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13586527 0,16034727 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13586527 0,16026984 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13586527 0,16019249 ! digestive system process GO:0022600 49 26 0,000 0,13586527 0,16011522 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13586527 0,16003802 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13586527 0,15996089 ! neural crest cell development GO:0014032 59 26 0,000 0,13586527 0,15988384 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13586527 0,15980686 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13586527 0,15972996 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13586527 0,15965313 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13586527 0,15957637 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13586527 0,15949969 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13586527 0,15942308 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13586527 0,15934654 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,13586527 0,15927008 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13586527 0,15919369 ! blastocyst development GO:0001824 50 26 0,000 0,13586527 0,15911738 ! telomere organization GO:0032200 46 26 0,000 0,13586527 0,15904113 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13586527 0,15896497 ! alditol metabolic process GO:0019400 44 26 0,000 0,13586527 0,15888887 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13586527 0,15881285 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13586527 0,15873689 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,14070684 0,16431491 ! embryonic pattern specification GO:0009880 49 27 0,000 0,14070684 0,16423641 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,14070684 0,16415797 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,14070684 0,16407962 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,14070684 0,16400133 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,14070684 0,16392313 ! iron ion transport GO:0006826 65 27 0,000 0,14070684 0,16384499 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,14070684 0,16376694 ! superoxide metabolic process GO:0006801 41 27 0,000 0,14070684 0,16368895 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,14070684 0,16361104 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,14070684 0,16353321 ! response to toxin GO:0009636 49 27 0,000 0,14070684 0,16345544 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,14070684 0,16337776 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,14070684 0,16330014 ! leukocyte proliferation GO:0070661 59 27 0,000 0,14070684 0,1632226 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,14552141 0,16872748 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,14552141 0,16864744 ! vesicle docking GO:0048278 55 28 0,000 0,14552141 0,16856748 ! circadian rhythm GO:0007623 56 28 0,000 0,14552141 0,16848759 ! dendrite development GO:0016358 67 28 0,000 0,14552141 0,16840777 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,14552141 0,16832804 ! fat cell differentiation GO:0045444 57 28 0,000 0,14552141 0,16824837 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,14552141 0,16816878 ! sperm motility GO:0030317 37 28 0,000 0,14552141 0,16808927 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,14552141 0,16800983 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,14552141 0,16793047 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,14552141 0,16785119 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,14552141 0,16777197 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,14552141 0,16769283 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,14552141 0,16761377 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,14552141 0,16753478 ! glutathione metabolic process GO:0006749 42 28 0,000 0,14552141 0,16745587 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,14552141 0,16737703 ! lipid oxidation GO:0034440 48 28 0,000 0,14552141 0,16729826 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,14552141 0,16721957 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,14552141 0,16714095 ! translational initiation GO:0006413 66 29 0,000 0,15030915 0,17255886 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,15030915 0,17247781 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,15030915 0,17239683 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,15030915 0,17231593 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,15030915 0,17223511 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,15030915 0,17215436 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,15030915 0,17207369 ! synaptogenesis GO:0007416 46 29 0,000 0,15030915 0,17199309 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,15030915 0,17191257 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,15030915 0,17183212 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,15030915 0,17175175 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,15030915 0,17167146 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,15507019 0,17702639 ! phenol metabolic process GO:0018958 56 30 0,000 0,15507019 0,17694371 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,15507019 0,1768611 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,15507019 0,17677857 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,15507019 0,17669612 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,15507019 0,17661374 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,15507019 0,17653144 ! acute-phase response GO:0006953 50 30 0,000 0,15507019 0,17644922 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,15507019 0,17636708 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,15507019 0,17628501 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,15507019 0,17620301 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,15507019 0,1761211 ! phospholipid transport GO:0015914 65 30 0,000 0,15507019 0,17603926 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,15507019 0,17595749 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,15507019 0,1758758 GO:0046496|nicotinamide nucleotide metabolic process, ! tissue homeostasis GO:0001894 50 30 0,000 0,15507019 0,17579419 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,15507019 0,17571265 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15980469 0,18099345 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15980469 0,18090958 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15980469 0,18082578 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15980469 0,18074207 ! cell junction assembly GO:0034329 85 31 0,000 0,15980469 0,18065843 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15980469 0,18057487 ! ovulation cycle process GO:0022602 55 31 0,000 0,15980469 0,18049138 ! peptide transport GO:0015833 60 31 0,000 0,15980469 0,18040798 ! male gonad development GO:0008584 56 31 0,000 0,15980469 0,18032465 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,15980469 0,1802414 ! detection of light stimulus GO:0009583 44 31 0,000 0,15980469 0,18015822 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,15980469 0,18007512 ! natural killer cell activation GO:0030101 50 31 0,000 0,15980469 0,1799921 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15980469 0,17990915 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15980469 0,17982628 ! response to heat GO:0009408 54 31 0,000 0,15980469 0,17974349 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15980469 0,17966077 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,1645128 0,18486879 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,1645128 0,1847838 ! collagen metabolic process GO:0032963 49 32 0,000 0,1645128 0,18469888 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1645128 0,18461404 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,1645128 0,18452927 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,1645128 0,18444459 ! mesoderm formation GO:0001707 73 32 0,000 0,1645128 0,18435998 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,1645128 0,18427545 ! ovulation cycle GO:0042698 57 32 0,000 0,1645128 0,184191 ! BMP signaling pathway GO:0030509 71 32 0,000 0,1645128 0,18410662 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,1645128 0,18402233 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,1645128 0,18393811 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,16919465 0,18908624 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16919465 0,18899978 GO:0055092|sterol homeostasis, ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16919465 0,1889134 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,16919465 0,1888271 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16919465 0,18874088 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,16919465 0,18865474 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16919465 0,18856867 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,1738504 0,19366918 ! post-embryonic development GO:0009791 76 34 0,000 0,1738504 0,19358091 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,1738504 0,19349272 ! cholesterol transport GO:0030301 62 34 0,000 0,1738504 0,19340461 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,1738504 0,19331658 ! spliceosome assembly GO:0000245 75 34 0,000 0,1738504 0,19322863 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1738504 0,19314075 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,1738504 0,19305296 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1738504 0,19296525 ! cell fate specification GO:0001708 56 34 0,000 0,1738504 0,19287762 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,1738504 0,19279007 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,17848018 0,19783443 ! negative regulation of secretion GO:0051048 68 35 0,000 0,17848018 0,19774471 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,17848018 0,19765507 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,17848018 0,19756551 ! membrane docking GO:0022406 69 35 0,000 0,17848018 0,19747604 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,17848018 0,19738664 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,17848018 0,19729733 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,17848018 0,19720809 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,17848018 0,19711894 ! ceramide metabolic process GO:0006672 72 35 0,000 0,17848018 0,19702986 ! sterol transport GO:0015918 63 35 0,000 0,17848018 0,19694087 ! placenta development GO:0001890 53 35 0,000 0,17848018 0,19685196 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,18308416 0,20183872 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,18308416 0,20174767 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,18308416 0,20165671 ! positive regulation of cell development GO:0010720 85 36 0,000 0,18308416 0,20156584 ! protein targeting to membrane GO:0006612 75 36 0,000 0,18308416 0,20147504 ! regulation of proteolysis GO:0030162 77 36 0,000 0,18308416 0,20138433 ! aerobic respiration GO:0009060 56 36 0,000 0,18308416 0,2012937 ! cytokine production GO:0001816 68 36 0,000 0,18308416 0,20120315 ! embryonic organ development GO:0048568 67 36 0,000 0,18308416 0,20111268 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,18308416 0,20102229 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,18308416 0,20093198 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,18766246 0,20586411 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,18766246 0,20577171 ! odontogenesis GO:0042476 74 37 0,000 0,18766246 0,2056794 ! cell junction organization GO:0034330 96 37 0,000 0,18766246 0,20558717 ! female gonad development GO:0008585 71 37 0,000 0,18766246 0,20549502 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,18766246 0,20540295 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,18766246 0,20531096 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,19221522 0,21019776 ! organic anion transport GO:0015711 82 38 0,000 0,19221522 0,21010371 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,19221522 0,21000975 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,19221522 0,20991587 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,19221522 0,20982207 ! spermatid development GO:0007286 69 38 0,000 0,19221522 0,20972836 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,19674261 0,2145724 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,19674261 0,21447666 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,19674261 0,21438099 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,19674261 0,21428541 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,20124474 0,21909131 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,20124474 0,21899372 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,20124474 0,21889621 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,20124474 0,2187988 ! mismatch repair GO:0006298 58 40 0,000 0,20124474 0,21870147 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,20124474 0,21860422 ! mRNA catabolic process GO:0006402 79 41 0,000 0,20572176 0,22336812 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,20572176 0,22326889 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,20572176 0,22316975 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,20572176 0,22307069 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,20572176 0,22297172 ! feeding behavior GO:0007631 69 41 0,000 0,20572176 0,22287285 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,20572176 0,22277405 ! mesenchymal cell development GO:0014031 94 41 0,000 0,20572176 0,22267535 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,20572176 0,22257673 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,20572176 0,22247821 ! RNA modification GO:0009451 64 41 0,000 0,20572176 0,22237976 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,21017382 0,22709184 ! organic ether metabolic process GO:0018904 59 42 0,000 0,21017382 0,22699144 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,21017382 0,22689114 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,21017382 0,22679092 ! regulation of protein secretion GO:0050708 77 42 0,000 0,21017382 0,22669079 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,21017382 0,22659075 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,21460105 0,23126174 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,21460105 0,23115977 ! regulation of tube size GO:0035150 76 43 0,000 0,21460105 0,23105789 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,21460105 0,2309561 ! glucose transport GO:0015758 66 43 0,000 0,21460105 0,23085441 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,21460105 0,2307528 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,21460105 0,23065128 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,21460105 0,23054985 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,21460105 0,23044851 ! ion transmembrane transport GO:0034220 79 43 0,000 0,21460105 0,23034726 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,21460105 0,23024609 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,21900358 0,23486644 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,21900358 0,23476338 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,21900358 0,23466042 ! hexose transport GO:0008645 68 44 0,000 0,21900358 0,23455754 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,21900358 0,23445475 ! striated muscle contraction GO:0006941 85 44 0,000 0,21900358 0,23435206 ! phagocytosis GO:0006909 105 44 0,000 0,21900358 0,23424945 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,21900358 0,23414694 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,22338156 0,23872316 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,22338156 0,23861878 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,22338156 0,23851449 ! biopolymer methylation GO:0043414 91 45 0,000 0,22338156 0,23841029 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,22338156 0,23830618 ! female gamete generation GO:0007292 71 45 0,000 0,22338156 0,23820216 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,22338156 0,23809823 ! polyol metabolic process GO:0019751 77 45 0,000 0,22338156 0,2379944 ! developmental growth GO:0048589 88 45 0,000 0,22338156 0,23789065 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,22773512 0,24242131 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,22773512 0,24231572 ! glycolysis GO:0006096 71 46 0,000 0,22773512 0,24221023 ! leukocyte migration GO:0050900 75 46 0,000 0,22773512 0,24210483 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,22773512 0,24199952 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,22773512 0,24189431 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,2320644 0,24638563 ! positive regulation of defense response GO:0031349 88 48 0,000 0,23636953 0,25084742 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,23636953 0,2507385 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,23636953 0,25062967 ! male sex differentiation GO:0046661 93 48 0,000 0,23636953 0,25052094 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,23636953 0,2504123 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,23636953 0,25030375 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,23636953 0,2501953 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,23636953 0,25008695 ! methylation GO:0032259 97 48 0,000 0,23636953 0,24997868 ! JNK cascade GO:0007254 106 49 0,000 0,24065065 0,25439616 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,24490788 0,25878458 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,24490788 0,2586727 ! regulation of ossification GO:0030278 123 50 0,000 0,24490788 0,25856091 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,24490788 0,25844922 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,24490788 0,25833763 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,24490788 0,25822613 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,24490788 0,25811473 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,24914136 0,26246328 ! peptide metabolic process GO:0006518 80 51 0,000 0,24914136 0,26235015 ! response to temperature stimulus GO:0009266 84 51 0,000 0,24914136 0,26223712 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,25335123 0,26655343 ! Notch signaling pathway GO:0007219 111 52 0,000 0,25335123 0,26643868 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,25335123 0,26632404 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,25335123 0,26620949 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,25335123 0,26609504 ! excretion GO:0007588 87 52 0,000 0,25335123 0,26598069 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,25335123 0,26586644 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,25753762 0,27014358 ! inner ear development GO:0048839 89 53 0,000 0,25753762 0,27002764 ! chromatin remodeling GO:0006338 122 53 0,000 0,25753762 0,2699118 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,25753762 0,26979605 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,25753762 0,26968041 ! regulation of translational initiation GO:0006446 87 54 0,000 0,26170064 0,27392231 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,26170064 0,273805 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,26170064 0,27368779 ! membrane fusion GO:0006944 122 54 0,000 0,26170064 0,27357068 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,26170064 0,27345367 ! RNA catabolic process GO:0006401 103 55 0,000 0,26584045 0,27766063 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,26584045 0,27754197 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,26584045 0,27742341 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,26584045 0,27730496 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,26995715 0,28147901 ! glucose catabolic process GO:0006007 88 56 0,000 0,26995715 0,28135893 ! chloride transport GO:0006821 102 57 0,000 0,27405089 0,28550376 ! regulation of actin filament length GO:0030832 118 58 0,000 0,27812178 0,28962128 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,27812178 0,28949788 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,27812178 0,28937458 ! gastrulation GO:0007369 122 58 0,000 0,27812178 0,28925139 ! regulation of endocytosis GO:0030100 104 60 0,000 0,28619556 0,2975216 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,28619556 0,29739504 ! positive regulation of secretion GO:0051047 110 61 0,000 0,29019869 0,30142661 ! regulation of cellular component size GO:0032535 125 61 0,000 0,29019869 0,30129851 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,29019869 0,30117052 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,29019869 0,30104263 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,29019869 0,30091485 ! proton transport GO:0015992 117 61 0,000 0,29019869 0,30078719 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,29019869 0,30065963 ! tRNA processing GO:0008033 102 62 0,000 0,29417948 0,30465471 ! mesoderm development GO:0007498 128 63 0,000 0,29813806 0,30862342 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,29813806 0,30849271 ! hydrogen transport GO:0006818 121 64 0,000 0,30207455 0,31243358 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,30207455 0,31230136 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,30598907 0,31621459 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,30598907 0,31608088 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,30598907 0,31594729 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,30598907 0,31581381 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,30598907 0,31568044 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,30988174 0,31956146 ! gonad development GO:0008406 115 66 0,000 0,30988174 0,31942662 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,31375269 0,3232804 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,31375269 0,32314411 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,31760204 0,32697083 ! hexose catabolic process GO:0019320 113 68 0,000 0,31760204 0,3268331 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,31760204 0,32669548 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,31760204 0,32655799 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,3214299 0,33035475 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,3214299 0,33021583 ! single fertilization GO:0007338 83 69 0,000 0,3214299 0,33007702 ! cell redox homeostasis GO:0045454 114 70 0,000 0,32523639 0,33384559 ! germ cell development GO:0007281 133 70 0,000 0,32523639 0,33370538 ! activation of immune response GO:0002253 120 70 0,000 0,32523639 0,33356528 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,32523639 0,33342531 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,32902164 0,33716438 ! carbohydrate transport GO:0008643 114 72 0,000 0,33278576 0,34087867 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,33278576 0,3407358 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,33278576 0,34059306 ! humoral immune response GO:0006959 115 73 0,000 0,33652888 0,34427975 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,33652888 0,34413564 ! regulation of immune effector process GO:0002697 156 73 0,000 0,33652888 0,34399165 ! acute inflammatory response GO:0002526 118 74 0,000 0,34025109 0,34765095 ! amino acid transport GO:0006865 148 74 0,000 0,34025109 0,34750561 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,34025109 0,34736039 ! transition metal ion transport GO:0000041 143 75 0,000 0,34395253 0,3509925 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,34395253 0,35084594 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,34763331 0,35445249 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,34763331 0,35430462 ! regulation of blood pressure GO:0008217 134 76 0,000 0,34763331 0,35415687 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,35129354 0,3577366 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,35129354 0,35758754 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,35129354 0,35743861 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,35493333 0,36099173 ! antigen processing and presentation GO:0019882 117 78 0,000 0,35493333 0,3608415 ! fertilization GO:0009566 99 78 0,000 0,35493333 0,3606914 ! blood coagulation GO:0007596 151 79 0,000 0,3585528 0,36421809 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,3585528 0,36406671 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,3585528 0,36391545 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,3585528 0,36376433 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,36215207 0,36726339 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,36215207 0,367111 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,36215207 0,36695873 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,37282975 0,3776215 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,37282975 0,37746501 ! inorganic anion transport GO:0015698 156 83 0,000 0,37282975 0,37730864 ! response to nutrient GO:0007584 135 84 0,000 0,3763493 0,38071277 ! digestion GO:0007586 130 84 0,000 0,3763493 0,38055519 ! hemostasis GO:0007599 165 85 0,000 0,3798492 0,38393529 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,3798492 0,38377651 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,3798492 0,38361786 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,38679048 0,39046659 ! alcohol catabolic process GO:0046164 142 87 0,000 0,38679048 0,39030531 ! nucleosome assembly GO:0006334 126 87 0,000 0,38679048 0,39014416 ! cellular respiration GO:0045333 143 88 0,000 0,39023208 0,39345314 ! sensory perception of smell GO:0007608 117 88 0,000 0,39023208 0,39329083 ! chromatin assembly GO:0031497 128 88 0,000 0,39023208 0,39312865 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,39023208 0,3929666 ! cellular defense response GO:0006968 123 89 0,000 0,39365445 0,39624962 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,39705772 0,39951071 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,39705772 0,39934624 ! defense response to bacterium GO:0042742 112 91 0,000 0,40044198 0,40258426 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,40380734 0,40580063 ! amine transport GO:0015837 181 93 0,000 0,4071539 0,40899547 ! vitamin metabolic process GO:0006766 153 93 0,000 0,4071539 0,40882736 ! female pregnancy GO:0007565 166 94 0,000 0,41048177 0,41199958 ! sterol metabolic process GO:0016125 166 94 0,000 0,41048177 0,41183038 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,41048177 0,41166132 ! regulation of defense response GO:0031347 171 95 0,000 0,41379106 0,41480983 ! nucleosome organization GO:0034728 143 95 0,000 0,41379106 0,41463968 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,41379106 0,41446968 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,41379106 0,41429982 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,41379106 0,41413009 ! mRNA transport GO:0051028 185 100 0,000 0,43006226 0,43023837 ! positive regulation of immune response GO:0050778 175 100 0,000 0,43006226 0,43006226