pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6869-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 6 6 4,000 3,354E-12 7,715E-09 ! negative regulation of peptide secretion GO:0002792 6 5 3,000 8,143E-10 9,365E-07 GO:0046676|negative regulation of insulin secretion, ! organ growth GO:0035265 11 7 3,000 5,669E-09 4,346E-06 ! regulation of growth hormone secretion GO:0060123 11 7 3,000 5,669E-09 3,26E-06 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 3,000 1,131E-08 5,201E-06 ! positive regulation of MAP kinase activity GO:0043406 121 85 6,000 2,481E-08 9,51E-06 ! DNA damage response, signal transduction GO:0042770 96 56 5,000 5,33E-08 1,751E-05 ! DNA damage checkpoint GO:0000077 53 31 4,000 8,853E-08 2,545E-05 ! carbohydrate homeostasis GO:0033500 39 33 4,000 1,23E-07 3,143E-05 GO:0042593|glucose homeostasis, ! DNA integrity checkpoint GO:0031570 57 34 4,000 1,438E-07 3,307E-05 ! regulation of intracellular protein transport GO:0033157 59 35 4,000 1,673E-07 3,497E-05 ! negative regulation of hormone secretion GO:0046888 20 15 3,000 2,163E-07 4,145E-05 ! cellular response to hormone stimulus GO:0032870 109 74 5,000 2,889E-07 5,111E-05 ! positive regulation of hormone secretion GO:0046887 24 17 3,000 3,75E-07 6,161E-05 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 4,000 4,297E-07 6,589E-05 ! response to UV GO:0009411 75 46 4,000 6,847E-07 9,843E-05 ! regulation of helicase activity GO:0051095 11 6 2,000 9,286E-07 1,256E-04 ! regulation of insulin secretion GO:0050796 26 21 3,000 9,328E-07 1,192E-04 ! regulation of intracellular transport GO:0032386 78 49 4,000 9,445E-07 1,143E-04 ! regulation of peptide secretion GO:0002791 34 25 3,000 1,95E-06 2,243E-04 ! activation of MAPK activity GO:0000187 84 59 4,000 2,411E-06 2,641E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,586E-06 2,704E-04 ! triglyceride metabolic process GO:0006641 34 28 3,000 3,13E-06 3,13E-04 ! cell cycle checkpoint GO:0000075 108 64 4,000 3,621E-06 3,47E-04 ! negative regulation of secretion GO:0051048 49 31 3,000 4,771E-06 4,39E-04 ! neutral lipid metabolic process GO:0006638 41 32 3,000 5,438E-06 4,81E-04 GO:0006639|acylglycerol metabolic process, ! negative regulation of transport GO:0051051 116 73 4,000 6,954E-06 5,924E-04 ! glycerol ether metabolic process GO:0006662 44 34 3,000 6,975E-06 5,729E-04 ! regulation of protein transport GO:0051223 114 76 4,000 8,482E-06 6,727E-04 GO:0070201|regulation of establishment of protein localization, ! regulation of hormone secretion GO:0046883 48 36 3,000 8,81E-06 6,755E-04 ! organic ether metabolic process GO:0018904 46 36 3,000 8,81E-06 6,537E-04 ! hormone-mediated signaling GO:0009755 49 36 3,000 8,81E-06 6,333E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 1,352E-05 9,423E-04 ! regulation of protein localization GO:0032880 132 85 4,000 1,468E-05 9,933E-04 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 2,174E-05 1,429E-03 ! response to light stimulus GO:0009416 153 96 4,000 2,653E-05 1,695E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 3,068E-05 1,907E-03 ! regulation of multicellular organism growth GO:0040014 65 50 3,000 3,315E-05 2,006E-03 ! positive regulation of secretion GO:0051047 71 51 3,000 3,587E-05 2,115E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 4,349E-05 2,5E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 5,103E-05 2,862E-03 ! multicellular organism reproduction GO:0032504 83 57 3,000 5,578E-05 3,054E-03 GO:0048609|reproductive process in a multicellular organism, ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 5,937E-05 3,176E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 6,857E-05 3,584E-03 ! protein tetramerization GO:0051262 39 22 2,000 6,857E-05 3,505E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 7,865E-05 3,932E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 8,965E-05 4,387E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 1,31E-04 6,277E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,31E-04 6,149E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,31E-04 6,026E-03 ! determination of adult lifespan GO:0008340 8 5 1,000 1,31E-04 5,908E-03 ! positive regulation of catabolic process GO:0009896 40 28 2,000 1,436E-04 6,351E-03 ! ER overload response GO:0006983 7 6 1,000 1,96E-04 8,507E-03 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 1,000 1,96E-04 8,35E-03 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 1,96E-04 8,198E-03 ! male meiosis GO:0007140 7 6 1,000 1,96E-04 8,052E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 1,000 1,96E-04 7,91E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,96E-04 7,774E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 1,96E-04 7,642E-03 ! male sex determination GO:0030238 9 6 1,000 1,96E-04 7,515E-03 ! negative regulation of DNA recombination GO:0045910 9 6 1,000 1,96E-04 7,392E-03 ! negative regulation of DNA metabolic process GO:0051053 48 32 2,000 2,152E-04 7,981E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 2,582E-04 9,427E-03 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 2,648E-04 9,517E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,738E-04 9,689E-03 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 1,000 2,738E-04 9,542E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! protein heterooligomerization GO:0051291 10 7 1,000 2,738E-04 9,399E-03 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 2,738E-04 9,261E-03 ! B cell lineage commitment GO:0002326 17 7 1,000 2,738E-04 9,127E-03 ! multicellular organismal aging GO:0010259 11 7 1,000 2,738E-04 8,997E-03 ! T cell lineage commitment GO:0002360 12 7 1,000 2,738E-04 8,87E-03 ! response to tumor cell GO:0002347 12 7 1,000 2,738E-04 8,747E-03 ! cell cycle arrest GO:0007050 150 86 3,000 2,77E-04 8,726E-03 ! hormone metabolic process GO:0042445 121 90 3,000 3,296E-04 0,01024558 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 3,642E-04 0,01116922 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 3,642E-04 0,01102225 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 3,642E-04 0,01087911 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 3,642E-04 0,01073963 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 3,642E-04 0,01060369 ! regulation of embryonic development GO:0045995 16 8 1,000 3,642E-04 0,01047114 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 3,893E-04 0,01105281 ! regulation of developmental growth GO:0048638 13 9 1,000 4,672E-04 0,01310352 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 4,672E-04 0,01294565 ! regulation of glycolysis GO:0006110 15 9 1,000 4,672E-04 0,01279153 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 4,672E-04 0,01264104 ! motor axon guidance GO:0008045 14 9 1,000 4,672E-04 0,01249406 ! localization within membrane GO:0051668 15 9 1,000 4,672E-04 0,01235045 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 5,202E-04 0,01359554 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 5,202E-04 0,01344278 ! response to insulin stimulus GO:0032868 63 43 2,000 5,202E-04 0,01329341 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 5,568E-04 0,0140726 ! negative regulation of muscle development GO:0048635 12 10 1,000 5,826E-04 0,01456457 ! regulation of B cell proliferation GO:0030888 15 10 1,000 5,826E-04 0,01440796 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 5,826E-04 0,01425469 ! response to X-ray GO:0010165 16 10 1,000 5,826E-04 0,01410464 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 5,826E-04 0,01395772 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 5,826E-04 0,01381382 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 6,764E-04 0,01587419 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! virus-host interaction GO:0019048 17 11 1,000 7,104E-04 0,01650344 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 7,104E-04 0,01633841 ! regulation of mRNA processing GO:0050684 18 11 1,000 7,104E-04 0,01617664 ! regulation of intracellular pH GO:0051453 17 11 1,000 7,104E-04 0,01601805 ! nitric oxide metabolic process GO:0046209 14 11 1,000 7,104E-04 0,01586253 GO:0006809|nitric oxide biosynthetic process, ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 1,000 7,104E-04 0,01571001 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 7,104E-04 0,01556039 GO:0042130|negative regulation of T cell proliferation, ! regulation of DNA replication GO:0006275 75 48 2,000 7,196E-04 0,01561381 ! regulation of angiogenesis GO:0045765 94 49 2,000 7,645E-04 0,0164338 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 8,504E-04 0,01811096 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 8,504E-04 0,0179448 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! immunoglobulin production during immune response GO:0002381 20 12 1,000 8,504E-04 0,01778167 ! histone acetylation GO:0016573 23 12 1,000 8,504E-04 0,01762147 ! peptidyl-lysine modification GO:0018205 18 12 1,000 8,504E-04 0,01746414 ! response to gamma radiation GO:0010332 20 12 1,000 8,504E-04 0,01730959 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 8,597E-04 0,01734425 ! positive regulation of cell migration GO:0030335 92 51 2,000 8,597E-04 0,01719343 ! aging GO:0007568 79 52 2,000 9,099E-04 0,01804175 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,003E-03 0,01971081 ! bone mineralization GO:0030282 15 13 1,000 1,003E-03 0,01954377 ! regulation of cellular pH GO:0030641 20 13 1,000 1,003E-03 0,01937953 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,003E-03 0,01921804 ! cytokine-mediated signaling pathway GO:0019221 76 54 2,000 1,016E-03 0,01931164 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,13E-03 0,02129391 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,167E-03 0,02182261 ! cellular response to starvation GO:0009267 21 14 1,000 1,167E-03 0,02164662 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,167E-03 0,02147345 ! G1/S transition checkpoint GO:0031575 33 14 1,000 1,167E-03 0,02130302 ! synaptic transmission, cholinergic GO:0007271 21 14 1,000 1,167E-03 0,02113528 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 1,167E-03 0,02097016 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 1,189E-03 0,02120198 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 1,343E-03 0,02376793 ! lipid phosphorylation GO:0046834 23 15 1,000 1,343E-03 0,02358649 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 1,343E-03 0,02340781 ! biomineral formation GO:0031214 18 15 1,000 1,343E-03 0,02323181 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 1,343E-03 0,02305844 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 1,343E-03 0,02288764 ! meiosis GO:0007126 96 61 2,000 1,448E-03 0,02448023 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell growth GO:0030308 106 62 2,000 1,517E-03 0,02547089 ! meiotic cell cycle GO:0051321 97 62 2,000 1,517E-03 0,02528632 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,532E-03 0,0253447 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,532E-03 0,02516366 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,532E-03 0,0249852 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 1,000 1,532E-03 0,02480925 ! negative regulation of cell size GO:0045792 108 64 2,000 1,663E-03 0,02674297 ! forelimb morphogenesis GO:0035136 19 17 1,000 1,732E-03 0,0276613 ! neuromuscular junction development GO:0007528 23 17 1,000 1,732E-03 0,02747053 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 1,732E-03 0,02728238 ! B cell activation GO:0042113 104 65 2,000 1,739E-03 0,02720327 ! protein oligomerization GO:0051259 100 65 2,000 1,739E-03 0,02701946 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,944E-03 0,03000386 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 1,944E-03 0,02980383 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 1,944E-03 0,02960646 ! prostaglandin metabolic process GO:0006693 31 18 1,000 1,944E-03 0,02941168 GO:0006692|prostanoid metabolic process, ! somitogenesis GO:0001756 24 18 1,000 1,944E-03 0,02921944 ! cellular response to nutrient levels GO:0031669 27 18 1,000 1,944E-03 0,02902971 ! negative regulation of T cell activation GO:0050868 25 18 1,000 1,944E-03 0,02884242 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 1,944E-03 0,02865753 ! regulation of catabolic process GO:0009894 106 70 2,000 2,151E-03 0,03150783 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 2,167E-03 0,0315491 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 2,167E-03 0,03135068 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,167E-03 0,03115474 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to starvation GO:0042594 30 19 1,000 2,167E-03 0,03096123 ! sex determination GO:0007530 29 19 1,000 2,167E-03 0,03077011 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 2,167E-03 0,03058134 ! somatic diversification of immunoglobulins GO:0016445 29 19 1,000 2,167E-03 0,03039487 ! hindlimb morphogenesis GO:0035137 32 20 1,000 2,402E-03 0,03348837 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 2,402E-03 0,03328663 ! positive regulation of inflammatory response GO:0050729 30 20 1,000 2,402E-03 0,03308731 ! positive regulation of B cell activation GO:0050871 31 20 1,000 2,402E-03 0,03289036 ! negative regulation of growth GO:0045926 123 75 2,000 2,619E-03 0,03564124 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 1,000 2,649E-03 0,03584027 GO:0016444|somatic cell DNA recombination, ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 2,649E-03 0,03563068 ! gluconeogenesis GO:0006094 25 21 1,000 2,649E-03 0,03542352 ! protein amino acid acylation GO:0043543 37 21 1,000 2,649E-03 0,03521876 ! regulation of DNA recombination GO:0000018 40 21 1,000 2,649E-03 0,03501635 ! cell aging GO:0007569 32 21 1,000 2,649E-03 0,03481626 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 2,649E-03 0,03461844 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,649E-03 0,03442286 ! immunoglobulin production GO:0002377 33 21 1,000 2,649E-03 0,03422947 GO:0002440|production of molecular mediator of immune response, ! protein import into nucleus, translocation GO:0000060 36 22 1,000 2,907E-03 0,03735396 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 2,907E-03 0,03714644 ! neural tube closure GO:0001843 33 22 1,000 2,907E-03 0,03694121 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of cell adhesion GO:0045785 37 23 1,000 3,176E-03 0,04014246 ! myelination GO:0042552 35 23 1,000 3,176E-03 0,0399231 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,176E-03 0,03970613 ! negative regulation of DNA replication GO:0008156 35 23 1,000 3,176E-03 0,0394915 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 3,176E-03 0,03927918 ! interaction with host GO:0051701 37 23 1,000 3,176E-03 0,03906913 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 3,176E-03 0,03886132 ! somatic diversification of immune receptors GO:0002200 35 23 1,000 3,176E-03 0,0386557 ! ossification GO:0001503 134 82 2,000 3,373E-03 0,04082928 GO:0060348|bone development, ! regulation of cellular catabolic process GO:0031329 36 24 1,000 3,457E-03 0,04163014 ! pyruvate metabolic process GO:0006090 29 24 1,000 3,457E-03 0,04141332 ! mitochondrial membrane organization GO:0007006 39 24 1,000 3,457E-03 0,04119874 ! response to toxin GO:0009636 38 24 1,000 3,457E-03 0,04098638 ! primary neural tube formation GO:0014020 35 24 1,000 3,457E-03 0,04077619 ! negative regulation of cell development GO:0010721 56 24 1,000 3,457E-03 0,04056815 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 3,457E-03 0,04036222 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,457E-03 0,04015837 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 3,749E-03 0,04332893 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 3,749E-03 0,04311229 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 3,749E-03 0,0428978 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 3,857E-03 0,04392162 ! skeletal muscle tissue development GO:0007519 123 87 2,000 3,985E-03 0,04514901 GO:0060538|skeletal muscle organ development, ! regulation of pH GO:0006885 36 26 1,000 4,052E-03 0,04568156 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 4,052E-03 0,04545872 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 4,052E-03 0,04523805 ! interphase GO:0051325 159 88 2,000 4,115E-03 0,04572064 ! response to ionizing radiation GO:0010212 47 27 1,000 4,366E-03 0,0482736 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 4,366E-03 0,04804262 ! negative regulation of protein transport GO:0051224 49 27 1,000 4,366E-03 0,04781385 ! ensheathment of neurons GO:0007272 43 28 1,000 4,69E-03 0,0511274 GO:0008366|axon ensheathment, ! neural tube formation GO:0001841 41 28 1,000 4,69E-03 0,05088623 ! regulation of B cell activation GO:0050864 42 28 1,000 4,69E-03 0,05064733 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 4,803E-03 0,05162459 ! mismatch repair GO:0006298 34 29 1,000 5,026E-03 0,05376636 ! hexose biosynthetic process GO:0019319 35 29 1,000 5,026E-03 0,05351744 ! tissue homeostasis GO:0001894 42 29 1,000 5,026E-03 0,05327081 GO:0048871|multicellular organismal homeostasis, ! embryonic epithelial tube formation GO:0001838 44 30 1,000 5,372E-03 0,05668064 ! negative regulation of cell activation GO:0050866 44 30 1,000 5,372E-03 0,05642182 ! mammary gland development GO:0030879 57 31 1,000 5,729E-03 0,05989788 ! xenobiotic metabolic process GO:0006805 44 31 1,000 5,729E-03 0,05962685 ! segmentation GO:0035282 41 31 1,000 5,729E-03 0,05935826 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 5,729E-03 0,05909208 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 5,729E-03 0,05882828 ! regulation of muscle development GO:0048634 48 32 1,000 6,097E-03 0,06232465 ! meiosis I GO:0007127 52 32 1,000 6,097E-03 0,06204888 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 6,097E-03 0,06177554 ! peripheral nervous system development GO:0007422 53 32 1,000 6,097E-03 0,06150459 ! calcium-mediated signaling GO:0019722 50 32 1,000 6,097E-03 0,06123601 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 6,097E-03 0,06096977 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 6,097E-03 0,06070583 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 6,475E-03 0,06419281 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 6,475E-03 0,06391731 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 6,864E-03 0,06746329 ! neuron migration GO:0001764 46 34 1,000 6,864E-03 0,06717621 ! regulation of action potential in neuron GO:0019228 54 35 1,000 7,263E-03 0,07077922 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 7,263E-03 0,07048057 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 7,672E-03 0,0741387 GO:0090047|positive regulation of transcription regulator activity, ! neural tube development GO:0021915 50 36 1,000 7,672E-03 0,07382849 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 7,672E-03 0,07352087 ! learning GO:0007612 67 37 1,000 8,091E-03 0,07721815 ! alcohol biosynthetic process GO:0046165 45 38 1,000 8,521E-03 0,08098102 ! regulation of T cell proliferation GO:0042129 58 38 1,000 8,521E-03 0,08064777 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 8,96E-03 0,08446038 ! synapse organization GO:0050808 55 39 1,000 8,96E-03 0,08411564 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 9,41E-03 0,08797632 ! T cell differentiation GO:0030217 65 40 1,000 9,41E-03 0,08762014 ! double-strand break repair GO:0006302 67 40 1,000 9,41E-03 0,08726683 ! B cell differentiation GO:0030183 62 40 1,000 9,41E-03 0,08691636 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 9,41E-03 0,0865687 ! positive regulation of DNA binding GO:0043388 57 41 1,000 9,869E-03 0,09043329 ! regulation of T cell differentiation GO:0045580 59 41 1,000 9,869E-03 0,09007443 ! mitochondrial transport GO:0006839 60 42 1,000 0,01033822 0,0939838 ! icosanoid metabolic process GO:0006690 61 42 1,000 0,01033822 0,09361378 ! positive regulation of binding GO:0051099 59 43 1,000 0,01081715 0,09756642 ! activation of caspase activity GO:0006919 65 43 1,000 0,01081715 0,0971853 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,01081715 0,09680715 ! regulation of action potential GO:0001508 71 44 1,000 0,01130574 0,10078756 ! regulation of inflammatory response GO:0050727 60 44 1,000 0,01130574 0,10039842 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,01180391 0,10441919 ! positive regulation of defense response GO:0031349 59 45 1,000 0,01180391 0,10401912 ! unsaturated fatty acid metabolic process GO:0033559 66 46 1,000 0,01231159 0,10807887 ! histone modification GO:0016570 68 46 1,000 0,01231159 0,10766792 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01282871 0,11176531 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01282871 0,11134355 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,01282871 0,11092497 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,0133552 0,11504477 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 65 48 1,000 0,0133552 0,1146155 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,0133552 0,11418942 GO:0019724|B cell mediated immunity, ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,0133552 0,11376649 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,01443596 0,12251922 ! lipid modification GO:0030258 73 50 1,000 0,01443596 0,12206878 ! positive regulation of growth GO:0045927 67 50 1,000 0,01443596 0,12162164 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01499009 0,12582926 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,01499009 0,1253717 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,01499009 0,12491745 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,0155533 0,12914293 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,0155533 0,12867839 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01670664 0,13772503 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01670664 0,13723315 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01817307 0,14874757 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01817307 0,1482201 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01817307 0,14769635 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01817307 0,1471763 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01817307 0,14665989 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01817307 0,14614709 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01817307 0,14563787 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01817307 0,14513218 ! sleep GO:0030431 11 5 0,000 0,01817307 0,14462999 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01817307 0,14413127 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01817307 0,14363597 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01817307 0,14314407 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01817307 0,14265552 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01817307 0,1421703 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01817307 0,14168837 ! tongue development GO:0043586 6 5 0,000 0,01817307 0,14120969 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01817307 0,14073424 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01817307 0,14026197 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01817307 0,13979287 ! cobalt ion transport GO:0006824 9 5 0,000 0,01817307 0,13932689 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01817307 0,13886401 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01817307 0,1384042 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01817307 0,13794742 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01817307 0,13749364 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01817307 0,13704285 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01817307 0,13659499 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01817307 0,13615006 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01817307 0,13570801 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01817307 0,13526883 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01817307 0,13483248 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01817307 0,13439893 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01817307 0,13396817 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01817307 0,13354015 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01817307 0,13311487 ! malate metabolic process GO:0006108 7 5 0,000 0,01817307 0,13269228 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01817307 0,13227237 ! behavioral response to pain GO:0048266 7 5 0,000 0,01817307 0,1318551 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01817307 0,13144047 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01817307 0,13102843 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01817307 0,13061896 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01817307 0,13021205 ! mating behavior GO:0007617 6 5 0,000 0,01817307 0,12980766 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01817307 0,12940578 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01817307 0,12900638 ! rhythmic behavior GO:0007622 12 5 0,000 0,01817307 0,12860944 ! copulation GO:0007620 7 5 0,000 0,01817307 0,12821493 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01817307 0,12782284 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01817307 0,12743313 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01817307 0,1270458 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01817307 0,12666081 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01817307 0,12627815 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01817307 0,1258978 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01817307 0,12551972 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01817307 0,12514392 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01817307 0,12477035 ! response to protozoan GO:0001562 9 5 0,000 0,01817307 0,12439901 ! lymph vessel development GO:0001945 7 5 0,000 0,01817307 0,12402988 ! endochondral ossification GO:0001958 12 5 0,000 0,01817307 0,12366292 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01817307 0,12329814 ! parathyroid gland development GO:0060017 8 5 0,000 0,01817307 0,12293549 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01817307 0,12257498 ! anagen GO:0042640 6 5 0,000 0,01817307 0,12221657 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01817307 0,12186026 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01817307 0,12150601 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01817307 0,12115382 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01817307 0,12080366 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01817307 0,12045553 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01817307 0,12010939 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01817307 0,11976524 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01817307 0,11942305 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01817307 0,11908281 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01817307 0,11874451 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01817307 0,11840812 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01817307 0,11807364 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01817307 0,11774104 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01817307 0,1174103 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01817307 0,11708142 ! ovulation GO:0030728 6 5 0,000 0,01817307 0,11675438 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01817307 0,11642916 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01817307 0,11610574 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01817307 0,11578412 ! response to pH GO:0009268 9 5 0,000 0,01817307 0,11546428 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01817307 0,11514619 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01817307 0,11482986 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01817307 0,11451525 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01817307 0,11420237 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01817307 0,11389119 ! polyol catabolic process GO:0046174 7 5 0,000 0,01817307 0,11358171 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01817307 0,1132739 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01817307 0,11296775 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01817307 0,11266326 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01817307 0,1123604 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01817307 0,11205916 ! urea metabolic process GO:0019627 6 5 0,000 0,01817307 0,11175954 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01817307 0,11146151 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01817307 0,11116507 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01817307 0,11087021 ! neutrophil activation GO:0042119 5 5 0,000 0,01817307 0,1105769 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01817307 0,11028514 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01817307 0,10999492 ! response to food GO:0032094 5 5 0,000 0,01817307 0,10970622 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01817307 0,10941903 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01817307 0,10913334 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01817307 0,10884914 ! forebrain neuron development GO:0021884 7 5 0,000 0,01817307 0,10856641 ! melanosome organization GO:0032438 7 5 0,000 0,01817307 0,10828515 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01817307 0,10800534 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01817307 0,10772698 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01817307 0,10745005 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01817307 0,10717453 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01817307 0,10690043 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01817307 0,10662772 ! nucleoside transport GO:0015858 6 5 0,000 0,01817307 0,10635641 ! nucleoside salvage GO:0043174 7 5 0,000 0,01817307 0,10608647 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01817307 0,10581789 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01817307 0,10555068 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01817307 0,10528481 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01817307 0,10502027 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01817307 0,10475706 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01817307 0,10449517 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01817307 0,10423458 ! depyrimidination GO:0045008 8 5 0,000 0,01817307 0,10397529 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01817307 0,10371729 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01817307 0,10346056 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01817307 0,10320511 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01817307 0,10295091 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01817307 0,10269796 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01817307 0,10244624 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01817307 0,10219577 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01817307 0,10194651 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01817307 0,10169846 ! monocyte differentiation GO:0030224 8 5 0,000 0,01817307 0,10145162 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01817307 0,10120598 ! centrosome duplication GO:0051298 5 5 0,000 0,01817307 0,10096152 ! response to UV-C GO:0010225 6 5 0,000 0,01817307 0,10071824 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01817307 0,10047612 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01817307 0,10023517 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01817307 0,09999538 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01817307 0,09975673 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01817307 0,09951921 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01817307 0,09928282 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01817307 0,09904755 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01817307 0,0988134 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01817307 0,09858035 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01817307 0,0983484 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01817307 0,09811753 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01817307 0,09788775 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01817307 0,09765904 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01817307 0,09743139 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01817307 0,09720481 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01817307 0,09697928 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01817307 0,09675479 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01817307 0,09653133 ! neural tube patterning GO:0021532 6 5 0,000 0,01817307 0,09630891 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01817307 0,09608751 ! histone demethylation GO:0016577 9 5 0,000 0,01817307 0,09586713 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01817307 0,09564775 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01817307 0,09542938 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01817307 0,095212 ! enteric nervous system development GO:0048484 8 5 0,000 0,01817307 0,09499561 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01817307 0,0947802 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01817307 0,09456576 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01817307 0,0943523 ! transcription termination GO:0006353 8 5 0,000 0,01817307 0,09413979 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01817307 0,09392824 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01817307 0,09371764 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01817307 0,09350798 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01817307 0,09329926 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01817307 0,09309147 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01817307 0,0928846 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01817307 0,09267864 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01817307 0,0924736 ! apical protein localization GO:0045176 6 5 0,000 0,01817307 0,09226947 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01817307 0,09206623 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01817307 0,09186389 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01817307 0,09166243 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01817307 0,09146186 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01817307 0,09126216 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01817307 0,09106333 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01817307 0,09086537 ! glial cell migration GO:0008347 10 5 0,000 0,01817307 0,09066826 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01817307 0,09047201 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01817307 0,0902766 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01817307 0,09008204 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01817307 0,08988832 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01817307 0,08969542 ! neural plate development GO:0001840 6 5 0,000 0,01817307 0,08950336 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01817307 0,08931211 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01817307 0,08912168 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01817307 0,08893206 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01817307 0,08874324 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01817307 0,08855523 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01817307 0,08836801 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01817307 0,08818158 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01817307 0,08799593 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01817307 0,08781107 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01817307 0,08762698 ! spindle assembly GO:0051225 5 5 0,000 0,01817307 0,08744366 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01817307 0,0872611 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01817307 0,08707931 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01817307 0,08689827 ! organ regeneration GO:0031100 7 5 0,000 0,01817307 0,08671798 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01817307 0,08653844 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01817307 0,08635964 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01817307 0,08618158 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01817307 0,08600426 GO:0055081|anion homeostasis, ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,01850292 0,08738547 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,01911907 0,09011038 ! viral reproductive process GO:0022415 87 58 1,000 0,01911907 0,0899261 ! lung development GO:0030324 94 59 1,000 0,0197438 0,09267497 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,02037704 0,09545251 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,02037704 0,0952585 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,02101871 0,09805891 ! respiratory tube development GO:0030323 99 62 1,000 0,02166877 0,10088697 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,02166877 0,10068315 ! tRNA transcription GO:0009304 11 6 0,000 0,02176848 0,10094255 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02176848 0,10073944 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02176848 0,10053716 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02176848 0,10033568 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02176848 0,10013501 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02176848 0,09993514 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02176848 0,09973606 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02176848 0,09953778 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02176848 0,09934028 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02176848 0,09914357 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02176848 0,09894764 ! prostate gland development GO:0030850 9 6 0,000 0,02176848 0,09875247 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02176848 0,09855808 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02176848 0,09836445 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02176848 0,09817158 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02176848 0,09797946 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02176848 0,09778809 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02176848 0,09759747 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02176848 0,09740759 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! neuron adhesion GO:0007158 9 6 0,000 0,02176848 0,09721845 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02176848 0,09703005 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02176848 0,09684237 ! signal peptide processing GO:0006465 8 6 0,000 0,02176848 0,09665541 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02176848 0,09646918 ! mRNA stabilization GO:0048255 15 6 0,000 0,02176848 0,09628366 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02176848 0,09609885 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02176848 0,09591476 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02176848 0,09573136 ! opsonization GO:0008228 8 6 0,000 0,02176848 0,09554867 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02176848 0,09536667 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02176848 0,09518537 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02176848 0,09500475 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02176848 0,09482482 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02176848 0,09464556 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02176848 0,09446699 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02176848 0,09428908 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02176848 0,09411185 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02176848 0,09393528 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02176848 0,09375937 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02176848 0,09358412 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02176848 0,09340952 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02176848 0,09323557 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02176848 0,09306227 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02176848 0,09288962 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02176848 0,0927176 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02176848 0,09254622 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02176848 0,09237547 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02176848 0,09220535 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02176848 0,09203585 ! thymic T cell selection GO:0045061 12 6 0,000 0,02176848 0,09186698 ! protein lipoylation GO:0009249 10 6 0,000 0,02176848 0,09169872 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02176848 0,09153108 ! pigment granule organization GO:0048753 11 6 0,000 0,02176848 0,09136406 ! drug transport GO:0015893 6 6 0,000 0,02176848 0,09119764 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02176848 0,09103182 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02176848 0,09086661 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02176848 0,090702 ! histidine metabolic process GO:0006547 6 6 0,000 0,02176848 0,09053798 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02176848 0,09037455 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02176848 0,09021172 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02176848 0,09004947 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02176848 0,0898878 ! adenohypophysis development GO:0021984 10 6 0,000 0,02176848 0,08972671 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02176848 0,0895662 ! hyperosmotic response GO:0006972 8 6 0,000 0,02176848 0,08940626 ! microtubule nucleation GO:0007020 10 6 0,000 0,02176848 0,08924689 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02176848 0,08908808 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02176848 0,08892985 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02176848 0,08877217 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02176848 0,08861505 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02176848 0,08845849 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02176848 0,08830248 ! response to dietary excess GO:0002021 7 6 0,000 0,02176848 0,08814701 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02176848 0,0879921 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02176848 0,08783773 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02176848 0,08768389 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02176848 0,0875306 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02176848 0,08737784 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02176848 0,08722562 ! neuron apoptosis GO:0051402 8 6 0,000 0,02176848 0,08707392 ! organic alcohol transport GO:0015850 9 6 0,000 0,02176848 0,08692275 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02176848 0,0867721 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02176848 0,08662198 ! carnitine transport GO:0015879 8 6 0,000 0,02176848 0,08647237 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02176848 0,08632328 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02176848 0,0861747 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02176848 0,08602664 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02176848 0,08587908 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02176848 0,08573203 ! parturition GO:0007567 12 6 0,000 0,02176848 0,08558548 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02176848 0,08543943 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02176848 0,08529387 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02176848 0,08514882 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02176848 0,08500425 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02176848 0,08486018 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02176848 0,08471659 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02176848 0,08457349 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02176848 0,08443087 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02176848 0,08428873 ! macrophage differentiation GO:0030225 10 6 0,000 0,02176848 0,08414706 ! astrocyte development GO:0014002 14 6 0,000 0,02176848 0,08400588 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02176848 0,08386516 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02176848 0,08372492 ! interaction with symbiont GO:0051702 8 6 0,000 0,02176848 0,08358515 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02176848 0,08344584 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02176848 0,08330699 ! eating behavior GO:0042755 6 6 0,000 0,02176848 0,08316861 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02176848 0,08303069 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02176848 0,08289322 ! response to copper ion GO:0046688 9 6 0,000 0,02176848 0,0827562 ! DNA topological change GO:0006265 8 6 0,000 0,02176848 0,08261964 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02176848 0,08248353 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02176848 0,08234787 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02176848 0,08221265 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02176848 0,08207787 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02176848 0,08194354 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02176848 0,08180965 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02176848 0,08167619 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02176848 0,08154317 ! gas homeostasis GO:0033483 11 6 0,000 0,02176848 0,08141057 ! hair follicle maturation GO:0048820 7 6 0,000 0,02176848 0,08127841 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02176848 0,08114668 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02176848 0,08101538 ! Schwann cell development GO:0014044 14 6 0,000 0,02176848 0,0808845 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02176848 0,08075404 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02176848 0,080624 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02176848 0,08049438 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02176848 0,08036517 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02176848 0,08023638 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02176848 0,08010801 ! histone ubiquitination GO:0016574 7 6 0,000 0,02176848 0,07998004 ! regulation of meiosis GO:0040020 10 6 0,000 0,02176848 0,07985248 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02176848 0,07972532 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02176848 0,07959857 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02176848 0,07947223 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02176848 0,07934628 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02176848 0,07922073 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02176848 0,07909558 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02176848 0,07897083 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02176848 0,07884646 ! receptor internalization GO:0031623 9 6 0,000 0,02176848 0,07872249 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02176848 0,07859891 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02176848 0,07847571 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02176848 0,0783529 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02176848 0,07823047 ! protein deubiquitination GO:0016579 8 6 0,000 0,02176848 0,07810843 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02176848 0,07798677 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02176848 0,07786548 ! axonal fasciculation GO:0007413 9 6 0,000 0,02176848 0,07774457 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02176848 0,07762404 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02176848 0,07750388 ! midbrain development GO:0030901 6 6 0,000 0,02176848 0,07738409 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02176848 0,07726467 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02176848 0,07714561 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02176848 0,07702693 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02176848 0,07690861 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02176848 0,07679065 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02176848 0,07667305 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02176848 0,07655582 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02176848 0,07643894 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02176848 0,07632241 ! adult feeding behavior GO:0008343 6 6 0,000 0,02176848 0,07620625 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02176848 0,07609043 ! blastocyst growth GO:0001832 15 6 0,000 0,02176848 0,07597497 ! pigment granule transport GO:0051904 12 6 0,000 0,02176848 0,07585985 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02176848 0,07574509 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02176848 0,07563067 ! catecholamine transport GO:0051937 7 6 0,000 0,02176848 0,0755166 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02176848 0,07540287 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02176848 0,07528948 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02176848 0,07517643 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02176848 0,07506372 ! protein prenylation GO:0018342 10 6 0,000 0,02176848 0,07495135 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02176848 0,07483932 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,02176848 0,07472762 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02176848 0,07461625 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02176848 0,07450521 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02176848 0,07439451 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02232712 0,07619048 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,02232712 0,0760776 ! viral reproduction GO:0016032 92 63 1,000 0,02232712 0,07596506 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02232712 0,07585285 ! appendage morphogenesis GO:0035107 93 64 1,000 0,02299372 0,07800228 GO:0035108|limb morphogenesis, ! respiratory system development GO:0060541 100 64 1,000 0,02299372 0,0778874 ! adaptive immune response GO:0002250 94 64 1,000 0,02299372 0,07777286 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 1,000 0,02366848 0,0799376 ! appendage development GO:0048736 94 65 1,000 0,02366848 0,07982039 GO:0060173|limb development, ! axon guidance GO:0007411 99 66 1,000 0,02435135 0,08200307 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,02435135 0,08188319 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,02504225 0,08408348 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02535093 0,08499581 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02535093 0,08487209 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02535093 0,08474873 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02535093 0,08462573 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02535093 0,08450308 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02535093 0,08438079 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02535093 0,08425886 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02535093 0,08413727 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02535093 0,08401603 ! reproductive behavior GO:0019098 12 7 0,000 0,02535093 0,08389515 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02535093 0,08377461 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02535093 0,08365442 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02535093 0,08353457 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02535093 0,08341506 ! oligopeptide transport GO:0006857 11 7 0,000 0,02535093 0,0832959 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02535093 0,08317707 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02535093 0,08305859 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02535093 0,08294044 ! RNA methylation GO:0001510 11 7 0,000 0,02535093 0,08282263 ! pericardium development GO:0060039 8 7 0,000 0,02535093 0,08270515 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02535093 0,082588 ! fibril organization GO:0043206 13 7 0,000 0,02535093 0,08247119 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02535093 0,0823547 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02535093 0,08223854 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02535093 0,08212272 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02535093 0,08200721 ! lipoprotein transport GO:0042953 9 7 0,000 0,02535093 0,08189203 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02535093 0,08177718 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02535093 0,08166264 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02535093 0,08154843 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02535093 0,08143454 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02535093 0,08132096 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02535093 0,0812077 ! chemosensory behavior GO:0007635 9 7 0,000 0,02535093 0,08109475 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02535093 0,08098212 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02535093 0,0808698 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02535093 0,0807578 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02535093 0,0806461 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02535093 0,08053471 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02535093 0,08042362 ! reflex GO:0060004 12 7 0,000 0,02535093 0,08031285 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02535093 0,08020238 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02535093 0,08009221 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02535093 0,07998234 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02535093 0,07987278 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02535093 0,07976351 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02535093 0,07965455 ! spinal cord patterning GO:0021511 7 7 0,000 0,02535093 0,07954588 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02535093 0,0794375 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02535093 0,07932943 ! adrenal gland development GO:0030325 17 7 0,000 0,02535093 0,07922164 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02535093 0,07911415 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02535093 0,07900695 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02535093 0,07890004 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02535093 0,07879342 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02535093 0,07868708 ! endosome organization GO:0007032 10 7 0,000 0,02535093 0,07858104 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02535093 0,07847527 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02535093 0,0783698 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02535093 0,0782646 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02535093 0,07815969 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02535093 0,07805506 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02535093 0,07795071 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02535093 0,07784663 ! galactose metabolic process GO:0006012 10 7 0,000 0,02535093 0,07774284 ! vesicle fusion GO:0006906 15 7 0,000 0,02535093 0,07763932 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02535093 0,07753607 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02535093 0,0774331 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02535093 0,07733041 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02535093 0,07722798 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02535093 0,07712583 ! retinol metabolic process GO:0042572 9 7 0,000 0,02535093 0,07702395 ! behavioral fear response GO:0001662 13 7 0,000 0,02535093 0,07692233 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02535093 0,07682099 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02535093 0,07671991 ! rRNA modification GO:0000154 12 7 0,000 0,02535093 0,07661909 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02535093 0,07651854 ! response to UV-B GO:0010224 11 7 0,000 0,02535093 0,07641825 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02535093 0,07631823 ! intermediate filament organization GO:0045109 11 7 0,000 0,02535093 0,07621847 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02535093 0,07611897 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02535093 0,07601972 ! fibrinolysis GO:0042730 9 7 0,000 0,02535093 0,07592074 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02535093 0,07582201 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02535093 0,07572354 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02535093 0,07562533 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02535093 0,07552737 ! response to tropane GO:0014073 13 7 0,000 0,02535093 0,07542966 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02535093 0,07533221 ! melanosome localization GO:0032400 10 7 0,000 0,02535093 0,075235 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02535093 0,07513805 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02535093 0,07504135 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02535093 0,07494489 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02535093 0,07484869 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02535093 0,07475273 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02535093 0,07465701 ! mast cell activation GO:0045576 9 7 0,000 0,02535093 0,07456154 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02535093 0,07446632 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02535093 0,07437134 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02535093 0,0742766 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02535093 0,0741821 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02535093 0,07408784 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02535093 0,07399382 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02535093 0,07390004 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02535093 0,07380649 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02535093 0,07371318 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02535093 0,07362011 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02535093 0,07352727 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02535093 0,07343467 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02535093 0,0733423 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02535093 0,07325016 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02535093 0,07315825 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02535093 0,07306658 ! diuresis GO:0030146 12 7 0,000 0,02535093 0,07297513 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02535093 0,07288391 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02535093 0,07279292 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02535093 0,07270215 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02535093 0,07261162 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02535093 0,0725213 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02535093 0,07243121 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02535093 0,07234135 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02535093 0,07225171 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02535093 0,07216229 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02535093 0,07207309 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02535093 0,07198411 ! lymph node development GO:0048535 9 7 0,000 0,02535093 0,07189535 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02535093 0,07180681 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02535093 0,07171848 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02535093 0,07163038 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02535093 0,07154249 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02535093 0,07145481 ! ATP catabolic process GO:0006200 10 7 0,000 0,02535093 0,07136735 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02535093 0,07128011 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02535093 0,07119307 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02535093 0,07110625 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02535093 0,07101964 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02535093 0,07093325 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02535093 0,07084706 ! muscle adaptation GO:0043500 12 7 0,000 0,02535093 0,07076108 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02535093 0,07067531 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02535093 0,07058974 ! retina homeostasis GO:0001895 9 7 0,000 0,02535093 0,07050439 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02535093 0,07041924 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02535093 0,07033429 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02535093 0,07024955 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02535093 0,07016502 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02535093 0,07008068 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02535093 0,06999655 ! learning or memory GO:0007611 123 68 1,000 0,02574113 0,07098873 ! response to drug GO:0042493 108 69 1,000 0,02644791 0,07285053 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,02716253 0,07472946 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,02788493 0,07662526 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,02788493 0,07653382 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,02788493 0,0764426 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,02861504 0,0783507 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,02861504 0,07825754 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,02861504 0,0781646 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02892046 0,07890516 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02892046 0,07881167 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,02892046 0,0787184 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02892046 0,07862535 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02892046 0,07853252 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02892046 0,07843991 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02892046 0,07834752 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02892046 0,07825535 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02892046 0,07816339 ! phosphate transport GO:0006817 10 8 0,000 0,02892046 0,07807165 ! N-glycan processing GO:0006491 12 8 0,000 0,02892046 0,07798013 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02892046 0,07788881 ! UTP metabolic process GO:0046051 8 8 0,000 0,02892046 0,07779772 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02892046 0,07770683 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02892046 0,07761616 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02892046 0,0775257 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02892046 0,07743545 ! succinate metabolic process GO:0006105 14 8 0,000 0,02892046 0,0773454 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02892046 0,07725557 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02892046 0,07716595 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02892046 0,07707653 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02892046 0,07698732 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02892046 0,07689832 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02892046 0,07680952 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02892046 0,07672093 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02892046 0,07663254 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02892046 0,07654436 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02892046 0,07645638 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02892046 0,0763686 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02892046 0,07628102 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02892046 0,07619364 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02892046 0,07610646 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02892046 0,07601948 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02892046 0,0759327 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02892046 0,07584612 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02892046 0,07575974 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02892046 0,07567355 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02892046 0,07558755 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02892046 0,07550176 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02892046 0,07541615 ! melanin metabolic process GO:0006582 12 8 0,000 0,02892046 0,07533074 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02892046 0,07524553 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02892046 0,07516051 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02892046 0,07507567 ! macrophage activation GO:0042116 12 8 0,000 0,02892046 0,07499103 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02892046 0,07490659 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02892046 0,07482233 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02892046 0,07473826 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02892046 0,07465437 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02892046 0,07457068 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02892046 0,07448718 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02892046 0,07440386 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02892046 0,07432072 ! ruffle organization GO:0031529 11 8 0,000 0,02892046 0,07423778 ! osteoblast development GO:0002076 13 8 0,000 0,02892046 0,07415501 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02892046 0,07407244 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02892046 0,07399004 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02892046 0,07390783 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02892046 0,0738258 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02892046 0,07374396 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02892046 0,07366229 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02892046 0,0735808 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02892046 0,0734995 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02892046 0,07341837 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02892046 0,07333743 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02892046 0,07325666 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02892046 0,07317607 ! segment specification GO:0007379 10 8 0,000 0,02892046 0,07309566 ! cellular extravasation GO:0045123 11 8 0,000 0,02892046 0,07301542 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02892046 0,07293536 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02892046 0,07285547 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02892046 0,07277576 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02892046 0,07269623 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02892046 0,07261686 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02892046 0,07253767 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02892046 0,07245866 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02892046 0,07237981 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02892046 0,07230114 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02892046 0,07222264 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02892046 0,0721443 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02892046 0,07206614 ! icosanoid secretion GO:0032309 12 8 0,000 0,02892046 0,07198815 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02892046 0,07191032 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02892046 0,07183266 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02892046 0,07175518 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02892046 0,07167785 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02892046 0,0716007 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02892046 0,07152371 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02892046 0,07144688 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02892046 0,07137022 ! sterol catabolic process GO:0016127 9 8 0,000 0,02892046 0,07129373 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02892046 0,0712174 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02892046 0,07114123 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02892046 0,07106522 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02892046 0,07098938 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02892046 0,0709137 ! prophase GO:0051324 11 8 0,000 0,02892046 0,07083818 ! S phase GO:0051320 8 8 0,000 0,02892046 0,07076282 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02892046 0,07068762 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02892046 0,07061258 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02892046 0,0705377 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02892046 0,07046297 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02892046 0,07038841 ! hormone catabolic process GO:0042447 13 8 0,000 0,02892046 0,070314 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02892046 0,07023975 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02892046 0,07016566 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02892046 0,07009173 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02892046 0,07001794 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02892046 0,06994432 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02892046 0,06987085 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02892046 0,06979753 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02892046 0,06972437 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02892046 0,06965136 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02892046 0,0695785 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02892046 0,0695058 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02892046 0,06943324 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02892046 0,06936084 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02892046 0,06928859 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02892046 0,06921649 ! tube morphogenesis GO:0035239 118 73 1,000 0,02935279 0,0701782 ! mitochondrion organization GO:0007005 104 73 1,000 0,02935279 0,07010533 ! response to oxygen levels GO:0070482 137 74 1,000 0,03009813 0,0718109 ! protein import into nucleus GO:0006606 118 74 1,000 0,03009813 0,07173648 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,03009813 0,07166222 ! nuclear import GO:0051170 121 75 1,000 0,03085099 0,07337878 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03237901 0,07693359 ! gland development GO:0048732 148 77 1,000 0,03237901 0,0768542 ! protein ubiquitination GO:0016567 125 77 1,000 0,03237901 0,07677497 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,03237901 0,0766959 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03247712 0,07684914 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03247712 0,07677016 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03247712 0,07669134 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03247712 0,07661268 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03247712 0,07653419 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03247712 0,07645585 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03247712 0,07637768 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03247712 0,07629966 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03247712 0,0762218 ! GTP metabolic process GO:0046039 9 9 0,000 0,03247712 0,07614411 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03247712 0,07606657 ! social behavior GO:0035176 14 9 0,000 0,03247712 0,07598918 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03247712 0,07591196 ! artery development GO:0060840 19 9 0,000 0,03247712 0,07583489 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03247712 0,07575798 ! response to pain GO:0048265 16 9 0,000 0,03247712 0,07568122 ! protein complex disassembly GO:0043241 17 9 0,000 0,03247712 0,07560462 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03247712 0,07552818 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03247712 0,07545189 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03247712 0,07537575 ! lung alveolus development GO:0048286 17 9 0,000 0,03247712 0,07529977 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03247712 0,07522393 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03247712 0,07514826 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03247712 0,07507273 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03247712 0,07499736 ! protein targeting to ER GO:0045047 19 9 0,000 0,03247712 0,07492213 ! T cell selection GO:0045058 18 9 0,000 0,03247712 0,07484706 ! endoderm development GO:0007492 12 9 0,000 0,03247712 0,07477214 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03247712 0,07469737 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03247712 0,07462274 ! arginine catabolic process GO:0006527 10 9 0,000 0,03247712 0,07454827 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03247712 0,07447395 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03247712 0,07439977 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03247712 0,07432574 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03247712 0,07425186 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03247712 0,07417812 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03247712 0,07410453 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03247712 0,07403109 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03247712 0,07395779 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03247712 0,07388464 ! mannose metabolic process GO:0006013 9 9 0,000 0,03247712 0,07381163 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03247712 0,07373876 ! receptor clustering GO:0043113 15 9 0,000 0,03247712 0,07366604 ! epithelial cell development GO:0002064 10 9 0,000 0,03247712 0,07359347 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03247712 0,07352103 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03247712 0,07344874 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03247712 0,07337659 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03247712 0,07330458 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03247712 0,07323271 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03247712 0,07316099 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03247712 0,0730894 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03247712 0,07301795 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03247712 0,07294665 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03247712 0,07287548 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03247712 0,07280445 ! DNA ligation GO:0006266 14 9 0,000 0,03247712 0,07273356 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03247712 0,07266281 ! response to amine stimulus GO:0014075 13 9 0,000 0,03247712 0,07259219 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03247712 0,07252172 ! erythrocyte development GO:0048821 11 9 0,000 0,03247712 0,07245137 ! renal water homeostasis GO:0003091 14 9 0,000 0,03247712 0,07238117 ! postreplication repair GO:0006301 11 9 0,000 0,03247712 0,0723111 ! mRNA cleavage GO:0006379 13 9 0,000 0,03247712 0,07224117 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03247712 0,07217137 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03247712 0,07210171 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03247712 0,07203218 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03247712 0,07196278 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03247712 0,07189352 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03247712 0,07182439 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03247712 0,0717554 ! acid secretion GO:0046717 14 9 0,000 0,03247712 0,07168653 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03247712 0,0716178 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03247712 0,0715492 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03247712 0,07148073 ! purine base metabolic process GO:0006144 18 9 0,000 0,03247712 0,0714124 ! oocyte differentiation GO:0009994 12 9 0,000 0,03247712 0,07134419 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03247712 0,07127611 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03247712 0,07120817 ! spleen development GO:0048536 15 9 0,000 0,03247712 0,07114035 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03247712 0,07107266 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03247712 0,0710051 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03247712 0,07093767 ! detection of calcium ion GO:0005513 13 9 0,000 0,03247712 0,07087037 ! blastocyst formation GO:0001825 12 9 0,000 0,03247712 0,07080319 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03247712 0,07073614 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03247712 0,07066922 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03247712 0,07060243 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03247712 0,07053576 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03247712 0,07046921 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03247712 0,0704028 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03247712 0,0703365 ! prepulse inhibition GO:0060134 14 9 0,000 0,03247712 0,07027034 ! embryonic placenta development GO:0001892 12 9 0,000 0,03247712 0,07020429 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03247712 0,07013837 ! insulin secretion GO:0030073 17 9 0,000 0,03247712 0,07007258 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03247712 0,0700069 ! response to nicotine GO:0035094 16 9 0,000 0,03247712 0,06994136 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03247712 0,06987593 ! nucleus localization GO:0051647 15 9 0,000 0,03247712 0,06981062 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03247712 0,06974544 ! T cell activation GO:0042110 134 79 1,000 0,03393635 0,0728112 ! protein localization in nucleus GO:0034504 133 80 1,000 0,03472586 0,07443568 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,03552252 0,07607244 GO:0002696|positive regulation of leukocyte activation, ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03602095 0,07706809 ! neuron fate specification GO:0048665 11 10 0,000 0,03602095 0,07699646 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03602095 0,07692497 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03602095 0,07685361 ! thyroid gland development GO:0030878 19 10 0,000 0,03602095 0,07678238 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03602095 0,07671129 ! synapsis GO:0007129 13 10 0,000 0,03602095 0,07664033 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03602095 0,07656949 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03602095 0,07649879 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03602095 0,07642822 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03602095 0,07635778 ! sulfate transport GO:0008272 12 10 0,000 0,03602095 0,07628747 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03602095 0,07621729 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03602095 0,07614724 ! androgen metabolic process GO:0008209 13 10 0,000 0,03602095 0,07607731 ! phospholipid efflux GO:0033700 16 10 0,000 0,03602095 0,07600752 ! hippocampus development GO:0021766 19 10 0,000 0,03602095 0,07593785 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,03602095 0,07586831 ! blood vessel remodeling GO:0001974 21 10 0,000 0,03602095 0,0757989 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03602095 0,07572961 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03602095 0,07566045 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03602095 0,07559142 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03602095 0,07552251 ! pathogenesis GO:0009405 13 10 0,000 0,03602095 0,07545373 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03602095 0,07538507 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03602095 0,07531654 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03602095 0,07524813 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03602095 0,07517985 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,03602095 0,07511169 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03602095 0,07504365 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03602095 0,07497574 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03602095 0,07490795 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03602095 0,07484028 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03602095 0,07477274 ! B cell proliferation GO:0042100 14 10 0,000 0,03602095 0,07470531 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03602095 0,07463801 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03602095 0,07457083 ! forebrain cell migration GO:0021885 17 10 0,000 0,03602095 0,07450377 ! lipid digestion GO:0044241 15 10 0,000 0,03602095 0,07443683 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03602095 0,07437001 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03602095 0,07430331 ! UV protection GO:0009650 14 10 0,000 0,03602095 0,07423673 ! entry into host cell GO:0030260 20 10 0,000 0,03602095 0,07417027 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03602095 0,07410393 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03602095 0,07403771 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03602095 0,0739716 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03602095 0,07390561 ! regulation of bone resorption GO:0045124 24 10 0,000 0,03602095 0,07383974 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03602095 0,07377399 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03602095 0,07370836 ! regulation of organ growth GO:0046620 11 10 0,000 0,03602095 0,07364284 ! response to dsRNA GO:0043331 18 10 0,000 0,03602095 0,07357744 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03602095 0,07351215 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03602095 0,07344698 ! embryonic axis specification GO:0000578 12 10 0,000 0,03602095 0,07338192 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03602095 0,07331698 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03602095 0,07325216 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03602095 0,07318745 ! cranial nerve development GO:0021545 12 10 0,000 0,03602095 0,07312285 ! fucose catabolic process GO:0019317 16 10 0,000 0,03602095 0,07305837 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03602095 0,072994 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03602095 0,07292975 ! protein sumoylation GO:0016925 12 10 0,000 0,03602095 0,0728656 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03602095 0,07280158 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03602095 0,07273766 ! zymogen activation GO:0031638 14 10 0,000 0,03602095 0,07267385 ! salivary gland development GO:0007431 22 10 0,000 0,03602095 0,07261016 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03602095 0,07254658 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03602095 0,07248311 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03602095 0,07241975 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03602095 0,0723565 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,03602095 0,07229336 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03602095 0,07223033 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03602095 0,07216742 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03602095 0,07210461 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03602095 0,07204191 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03602095 0,07197932 ! detection of bacterium GO:0016045 10 10 0,000 0,03602095 0,07191683 ! embryonic gut development GO:0048566 11 10 0,000 0,03602095 0,07185446 ! activation of innate immune response GO:0002218 10 10 0,000 0,03602095 0,07179219 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03602095 0,07173004 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03602095 0,07166799 ! developmental induction GO:0031128 13 10 0,000 0,03602095 0,07160604 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03602095 0,07154421 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,03602095 0,07148248 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03602095 0,07142086 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03602095 0,07135934 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,03713703 0,07350702 ! regulation of defense response GO:0031347 117 84 1,000 0,03795475 0,07506099 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,03877939 0,07662593 ! regulation of membrane potential GO:0042391 128 85 1,000 0,03877939 0,07656016 ! rRNA transcription GO:0009303 17 11 0,000 0,03955201 0,07801855 ! respiratory burst GO:0045730 14 11 0,000 0,03955201 0,07795169 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03955201 0,07788496 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03955201 0,07781833 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03955201 0,07775182 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03955201 0,07768542 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03955201 0,07761914 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03955201 0,07755296 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03955201 0,07748691 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03955201 0,07742096 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03955201 0,07735513 ! mating GO:0007618 14 11 0,000 0,03955201 0,0772894 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03955201 0,07722379 ! T cell proliferation GO:0042098 20 11 0,000 0,03955201 0,07715829 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03955201 0,0770929 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03955201 0,07702763 ! bone resorption GO:0045453 16 11 0,000 0,03955201 0,07696246 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03955201 0,0768974 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03955201 0,07683246 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03955201 0,07676762 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03955201 0,07670289 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03955201 0,07663827 ! syncytium formation GO:0006949 15 11 0,000 0,03955201 0,07657376 ! plasma membrane organization GO:0007009 18 11 0,000 0,03955201 0,07650936 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03955201 0,07644507 ! focal adhesion formation GO:0048041 24 11 0,000 0,03955201 0,07638088 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03955201 0,0763168 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03955201 0,07625283 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03955201 0,07618897 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03955201 0,07612521 ! adult heart development GO:0007512 11 11 0,000 0,03955201 0,07606156 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03955201 0,07599802 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,03955201 0,07593458 ! temperature homeostasis GO:0001659 16 11 0,000 0,03955201 0,07587125 ! L-glutamate transport GO:0015813 16 11 0,000 0,03955201 0,07580802 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03955201 0,0757449 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03955201 0,07568189 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03955201 0,07561898 ! stem cell development GO:0048864 29 11 0,000 0,03955201 0,07555617 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03955201 0,07549347 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03955201 0,07543087 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03955201 0,07536837 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03955201 0,07530598 ! vasoconstriction GO:0042310 15 11 0,000 0,03955201 0,0752437 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03955201 0,07518151 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03955201 0,07511943 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03955201 0,07505745 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03955201 0,07499557 ! ribosome assembly GO:0042255 13 11 0,000 0,03955201 0,0749338 ! histone deacetylation GO:0016575 13 11 0,000 0,03955201 0,07487212 ! chromatin silencing GO:0006342 19 11 0,000 0,03955201 0,07481055 ! nucleosome positioning GO:0016584 13 11 0,000 0,03955201 0,07474908 ! T cell homeostasis GO:0043029 20 11 0,000 0,03955201 0,07468771 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03955201 0,07462644 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03955201 0,07456527 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03955201 0,0745042 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03955201 0,07444323 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03955201 0,07438236 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03955201 0,07432159 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03955201 0,07426092 ! oxygen transport GO:0015671 15 11 0,000 0,03955201 0,07420035 ! male genitalia development GO:0030539 13 11 0,000 0,03955201 0,07413988 ! cholesterol efflux GO:0033344 19 11 0,000 0,03955201 0,0740795 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03955201 0,07401923 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03955201 0,07395905 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03955201 0,07389897 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03955201 0,07383898 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03955201 0,0737791 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03955201 0,07371931 ! defense response to fungus GO:0050832 12 11 0,000 0,03955201 0,07365962 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03955201 0,07360002 ! lysogeny GO:0030069 18 11 0,000 0,03955201 0,07354052 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03955201 0,07348112 ! acrosome reaction GO:0007340 13 11 0,000 0,03955201 0,07342181 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03955201 0,0733626 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,04044912 0,07496613 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,0412941 0,07647056 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,04214575 0,0779849 ! reproductive developmental process GO:0003006 127 89 1,000 0,04214575 0,07792221 ! regulation of T cell activation GO:0050863 128 89 1,000 0,04214575 0,07785962 ! leukocyte differentiation GO:0002521 143 90 1,000 0,04300401 0,07938139 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,04300401 0,07931773 ! lactation GO:0007595 20 12 0,000 0,04307034 0,07937642 ! reproductive cellular process GO:0048610 14 12 0,000 0,04307034 0,07931287 ! tRNA modification GO:0006400 14 12 0,000 0,04307034 0,07924942 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04307034 0,07918607 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04307034 0,07912283 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04307034 0,07905968 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04307034 0,07899663 ! non-recombinational repair GO:0000726 19 12 0,000 0,04307034 0,07893369 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04307034 0,07887084 ! peroxisomal transport GO:0043574 21 12 0,000 0,04307034 0,0788081 ! cartilage condensation GO:0001502 18 12 0,000 0,04307034 0,07874545 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04307034 0,0786829 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04307034 0,07862046 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04307034 0,07855811 ! heart looping GO:0001947 15 12 0,000 0,04307034 0,07849586 ! palate development GO:0060021 15 12 0,000 0,04307034 0,07843371 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04307034 0,07837166 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04307034 0,07830971 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04307034 0,07824785 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04307034 0,07818609 ! arginine metabolic process GO:0006525 13 12 0,000 0,04307034 0,07812443 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04307034 0,07806287 ! methionine metabolic process GO:0006555 13 12 0,000 0,04307034 0,0780014 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04307034 0,07794003 ! Golgi organization GO:0007030 18 12 0,000 0,04307034 0,07787876 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04307034 0,07781758 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04307034 0,0777565 ! monoamine transport GO:0015844 13 12 0,000 0,04307034 0,07769551 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04307034 0,07763462 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04307034 0,07757383 ! L-amino acid transport GO:0015807 20 12 0,000 0,04307034 0,07751313 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04307034 0,07745252 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04307034 0,07739201 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04307034 0,0773316 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04307034 0,07727128 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04307034 0,07721105 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04307034 0,07715092 ! cerebellum development GO:0021549 13 12 0,000 0,04307034 0,07709088 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04307034 0,07703093 ! histone methylation GO:0016571 15 12 0,000 0,04307034 0,07697108 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04307034 0,07691132 ! gland morphogenesis GO:0022612 23 12 0,000 0,04307034 0,07685165 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04307034 0,07679208 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04307034 0,07673259 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04307034 0,0766732 ! intestinal absorption GO:0050892 19 12 0,000 0,04307034 0,0766139 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04307034 0,0765547 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04307034 0,07649558 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,04307034 0,07643656 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04307034 0,07637762 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,04307034 0,07631878 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04307034 0,07626003 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04307034 0,07620137 ! microspike assembly GO:0030035 23 12 0,000 0,04307034 0,0761428 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04307034 0,07608431 ! response to cold GO:0009409 14 12 0,000 0,04307034 0,07602592 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,04474011 0,07891277 ! cell fate commitment GO:0045165 141 92 1,000 0,04474011 0,0788523 ! DNA recombination GO:0006310 146 92 1,000 0,04474011 0,07879192 ! response to oxidative stress GO:0006979 141 94 1,000 0,04650195 0,08183204 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04657598 0,08189965 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04657598 0,08183709 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04657598 0,08177461 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04657598 0,08171224 ! water transport GO:0006833 17 13 0,000 0,04657598 0,08164996 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04657598 0,08158777 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04657598 0,08152568 ! lipid localization GO:0010876 24 13 0,000 0,04657598 0,08146368 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04657598 0,08140178 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04657598 0,08133997 ! organelle fusion GO:0048284 28 13 0,000 0,04657598 0,08127826 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04657598 0,08121664 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04657598 0,08115511 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,04657598 0,08109368 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04657598 0,08103233 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04657598 0,08097108 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04657598 0,08090993 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04657598 0,08084886 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04657598 0,08078789 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04657598 0,08072701 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04657598 0,08066622 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04657598 0,08060553 ! NAD metabolic process GO:0019674 21 13 0,000 0,04657598 0,08054492 ! exocrine system development GO:0035272 27 13 0,000 0,04657598 0,08048441 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04657598 0,08042398 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04657598 0,08036365 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04657598 0,08030341 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04657598 0,08024325 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04657598 0,08018319 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04657598 0,08012322 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04657598 0,08006334 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,04657598 0,08000354 ! genitalia development GO:0048806 15 13 0,000 0,04657598 0,07994384 ! cellular pigmentation GO:0033059 24 13 0,000 0,04657598 0,07988422 ! tissue regeneration GO:0042246 21 13 0,000 0,04657598 0,0798247 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04657598 0,07976526 ! cofactor transport GO:0051181 19 13 0,000 0,04657598 0,07970591 ! NADP metabolic process GO:0006739 18 13 0,000 0,04657598 0,07964665 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04657598 0,07958748 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04657598 0,07952839 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04657598 0,0794694 ! gas transport GO:0015669 18 13 0,000 0,04657598 0,07941049 ! regulation of RNA stability GO:0043487 28 13 0,000 0,04657598 0,07935166 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04657598 0,07929293 ! regulation of axon extension GO:0030516 23 13 0,000 0,04657598 0,07923428 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04657598 0,07917572 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04657598 0,07911724 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04657598 0,07905885 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04657598 0,07900055 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04657598 0,07894233 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04657598 0,0788842 ! regulation of binding GO:0051098 151 95 1,000 0,04739238 0,08020785 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,04828907 0,08166534 ! in utero embryonic development GO:0001701 147 96 1,000 0,04828907 0,08160533 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,04828907 0,08154542 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,04919197 0,08300919 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05006897 0,08442715 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,05006897 0,0843653 ! superoxide anion generation GO:0042554 18 14 0,000 0,05006897 0,08430354 ! neuron maturation GO:0042551 21 14 0,000 0,05006897 0,08424187 ! regulation of S phase GO:0033261 18 14 0,000 0,05006897 0,08418029 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05006897 0,0841188 ! myotube differentiation GO:0014902 21 14 0,000 0,05006897 0,0840574 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,05006897 0,08399609 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,05006897 0,08393486 ! inositol metabolic process GO:0006020 20 14 0,000 0,05006897 0,08387373 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05006897 0,08381269 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05006897 0,08375173 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05006897 0,08369087 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05006897 0,08363009 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05006897 0,0835694 ! response to cAMP GO:0051591 19 14 0,000 0,05006897 0,0835088 ! limbic system development GO:0021761 25 14 0,000 0,05006897 0,08344829 ! startle response GO:0001964 21 14 0,000 0,05006897 0,08338786 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,05006897 0,08332752 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05006897 0,08326727 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,05006897 0,08320711 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05006897 0,08314703 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,05006897 0,08308704 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,05006897 0,08302713 ! glycine metabolic process GO:0006544 22 14 0,000 0,05006897 0,08296732 ! pituitary gland development GO:0021983 23 14 0,000 0,05006897 0,08290758 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,05006897 0,08284794 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,05006897 0,08278838 ! regulation of heart rate GO:0002027 23 14 0,000 0,05006897 0,0827289 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05006897 0,08266952 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,05006897 0,08261021 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05006897 0,08255099 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05006897 0,08249186 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,05006897 0,08243281 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,05006897 0,08237384 ! axon cargo transport GO:0008088 27 14 0,000 0,05006897 0,08231496 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,05006897 0,08225617 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05006897 0,08219746 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05006897 0,08213883 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,05006897 0,08208028 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05006897 0,08202182 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05006897 0,08196344 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05006897 0,08190515 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05006897 0,08184693 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05006897 0,0817888 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05006897 0,08173076 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05006897 0,08167279 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,05006897 0,08161491 ! muscle maintenance GO:0046716 19 14 0,000 0,05006897 0,08155711 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,05006897 0,08149939 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05006897 0,08144175 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05006897 0,08138419 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05006897 0,08132672 ! cell killing GO:0001906 20 14 0,000 0,05006897 0,08126933 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,05006897 0,08121201 ! cilium assembly GO:0042384 20 14 0,000 0,05006897 0,08115478 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05006897 0,08109763 ! extracellular structure organization GO:0043062 156 99 1,000 0,05101617 0,08257367 ! protein import GO:0017038 156 99 1,000 0,05101617 0,0825156 ! protein localization in organelle GO:0033365 161 100 1,000 0,05193736 0,08394654 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05354937 0,08649126 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05354937 0,08643056 ! metencephalon development GO:0022037 19 15 0,000 0,05354937 0,08636995 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05354937 0,08630942 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05354937 0,08624898 ! skin development GO:0043588 25 15 0,000 0,05354937 0,08618863 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05354937 0,08612836 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05354937 0,08606817 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05354937 0,08600807 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05354937 0,08594805 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05354937 0,08588811 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05354937 0,08582826 ! adult walking behavior GO:0007628 25 15 0,000 0,05354937 0,08576849 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05354937 0,0857088 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05354937 0,0856492 ! myoblast differentiation GO:0045445 27 15 0,000 0,05354937 0,08558968 ! centrosome cycle GO:0007098 16 15 0,000 0,05354937 0,08553024 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05354937 0,08547089 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05354937 0,08541162 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05354937 0,08535242 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05354937 0,08529332 ! cerebral cortex development GO:0021987 29 15 0,000 0,05354937 0,08523429 ! response to osmotic stress GO:0006970 22 15 0,000 0,05354937 0,08517535 ! vesicle coating GO:0006901 25 15 0,000 0,05354937 0,08511648 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,05354937 0,0850577 ! DNA integration GO:0015074 22 15 0,000 0,05354937 0,084999 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05354937 0,08494038 ! peptide secretion GO:0002790 27 15 0,000 0,05354937 0,08488184 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05354937 0,08482338 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05354937 0,084765 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05354937 0,08470671 ! neuron recognition GO:0008038 22 15 0,000 0,05354937 0,08464849 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05354937 0,08459035 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05354937 0,08453229 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05354937 0,08447431 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,05354937 0,08441641 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05354937 0,0843586 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05354937 0,08430085 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05354937 0,08424319 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05354937 0,08418561 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05354937 0,08412811 ! organic cation transport GO:0015695 19 15 0,000 0,05354937 0,08407068 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05354937 0,08401333 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05354937 0,08395607 ! defense response to virus GO:0051607 27 15 0,000 0,05354937 0,08389888 ! peptide hormone processing GO:0016486 19 15 0,000 0,05354937 0,08384176 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05354937 0,08378473 ! protein secretion GO:0009306 27 16 0,000 0,05701721 0,08914996 ! hormone secretion GO:0046879 25 16 0,000 0,05701721 0,0890894 ! bone remodeling GO:0046849 24 16 0,000 0,05701721 0,08902891 ! endothelial cell migration GO:0043542 22 16 0,000 0,05701721 0,08896852 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05701721 0,0889082 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05701721 0,08884796 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05701721 0,08878781 ! glial cell development GO:0021782 24 16 0,000 0,05701721 0,08872773 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05701721 0,08866774 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05701721 0,08860783 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05701721 0,088548 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05701721 0,08848825 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05701721 0,08842858 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05701721 0,088369 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05701721 0,08830949 ! fructose metabolic process GO:0006000 20 16 0,000 0,05701721 0,08825006 ! regulation of protein binding GO:0043393 27 16 0,000 0,05701721 0,08819071 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05701721 0,08813145 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05701721 0,08807226 ! protein export from nucleus GO:0006611 24 16 0,000 0,05701721 0,08801315 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05701721 0,08795412 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05701721 0,08789517 ! DNA replication initiation GO:0006270 25 16 0,000 0,05701721 0,0878363 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05701721 0,0877775 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05701721 0,08771879 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05701721 0,08766015 ! diencephalon development GO:0021536 25 16 0,000 0,05701721 0,0876016 ! oogenesis GO:0048477 23 16 0,000 0,05701721 0,08754312 ! neural crest cell migration GO:0001755 24 16 0,000 0,05701721 0,08748472 ! G1 phase GO:0051318 27 16 0,000 0,05701721 0,08742639 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,05701721 0,08736815 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05701721 0,08730998 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05701721 0,08725189 ! steroid catabolic process GO:0006706 22 16 0,000 0,05701721 0,08719388 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05701721 0,08713594 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05701721 0,08707808 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05701721 0,0870203 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05701721 0,08696259 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05701721 0,08690496 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 0,000 0,05701721 0,08684741 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05701721 0,08678993 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05701721 0,08673253 ! negative regulation of translation GO:0017148 22 16 0,000 0,05701721 0,08667521 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,06047255 0,09186715 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,06047255 0,09180651 ! negative regulation of defense response GO:0031348 19 17 0,000 0,06047255 0,09174595 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,06047255 0,09168547 ! glycerol metabolic process GO:0006071 20 17 0,000 0,06047255 0,09162508 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,06047255 0,09156476 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,06047255 0,09150452 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,06047255 0,09144436 ! signal complex assembly GO:0007172 29 17 0,000 0,06047255 0,09138427 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,06047255 0,09132427 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,06047255 0,09126435 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,06047255 0,0912045 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,06047255 0,09114473 ! memory GO:0007613 25 17 0,000 0,06047255 0,09108505 ! keratinization GO:0031424 17 17 0,000 0,06047255 0,09102543 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,06047255 0,0909659 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,06047255 0,09090645 ! retinoid metabolic process GO:0001523 22 17 0,000 0,06047255 0,09084707 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,06047255 0,09078777 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,06047255 0,09072855 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,06047255 0,0906694 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,06047255 0,09061034 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,06047255 0,09055134 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,06047255 0,09049243 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,06047255 0,09043359 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,06047255 0,09037483 ! membrane budding GO:0006900 29 17 0,000 0,06047255 0,09031615 ! heme metabolic process GO:0042168 27 17 0,000 0,06047255 0,09025754 ! actin filament bundle formation GO:0051017 26 17 0,000 0,06047255 0,090199 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,06047255 0,09014055 ! body fluid secretion GO:0007589 27 17 0,000 0,06047255 0,09008217 ! stem cell differentiation GO:0048863 36 17 0,000 0,06047255 0,09002386 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,06047255 0,08996563 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,06047255 0,08990748 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,06047255 0,0898494 ! sensory perception of pain GO:0019233 23 17 0,000 0,06047255 0,08979139 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,06047255 0,08973346 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,06047255 0,08967561 ! synaptogenesis GO:0007416 24 17 0,000 0,06047255 0,08961782 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,06047255 0,08956012 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,06047255 0,08950249 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,06047255 0,08944493 ! cell-cell junction organization GO:0045216 25 17 0,000 0,06047255 0,08938744 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,06047255 0,08933003 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,06047255 0,0892727 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,06047255 0,08921544 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,06047255 0,08915825 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,06047255 0,08910113 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,06047255 0,08904409 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,06391542 0,0940534 ! positive regulation of translation GO:0045727 28 18 0,000 0,06391542 0,09399327 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06391542 0,09393321 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06391542 0,09387322 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06391542 0,09381332 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06391542 0,09375349 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06391542 0,09369373 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06391542 0,09363406 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06391542 0,09357446 ! axis specification GO:0009798 26 18 0,000 0,06391542 0,09351493 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06391542 0,09345548 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06391542 0,09339611 ! pancreas development GO:0031016 26 18 0,000 0,06391542 0,09333681 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06391542 0,09327758 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06391542 0,09321843 ! response to retinoic acid GO:0032526 25 18 0,000 0,06391542 0,09315936 ! pigmentation during development GO:0048066 31 18 0,000 0,06391542 0,09310036 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06391542 0,09304144 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06391542 0,09298259 ! fucose metabolic process GO:0006004 26 18 0,000 0,06391542 0,09292381 ! response to fungus GO:0009620 19 18 0,000 0,06391542 0,09286511 ! peptide cross-linking GO:0018149 31 18 0,000 0,06391542 0,09280648 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06391542 0,09274793 ! heart process GO:0003015 27 18 0,000 0,06391542 0,09268945 GO:0060047|heart contraction, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06391542 0,09263105 ! visual learning GO:0008542 35 18 0,000 0,06391542 0,09257271 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06391542 0,09251446 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06391542 0,09245627 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06391542 0,09239816 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06391542 0,09234012 ! vitamin transport GO:0051180 24 18 0,000 0,06391542 0,09228215 ! hormone transport GO:0009914 27 18 0,000 0,06391542 0,09222426 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06391542 0,09216644 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06391542 0,09210869 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06391542 0,09205101 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06391542 0,09199341 ! cell-cell recognition GO:0009988 20 18 0,000 0,06391542 0,09193588 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06391542 0,09187842 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06391542 0,09182103 ! regulation of glucose import GO:0046324 21 18 0,000 0,06391542 0,09176371 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,06391542 0,09170647 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06391542 0,0916493 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06734587 0,09650811 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06734587 0,09644801 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06734587 0,096388 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06734587 0,09632805 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06734587 0,09626818 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06734587 0,09620839 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06734587 0,09614867 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06734587 0,09608903 ! regeneration GO:0031099 32 19 0,000 0,06734587 0,09602945 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,06734587 0,09596996 ! response to alkaloid GO:0043279 32 19 0,000 0,06734587 0,09591053 ! sensory perception of taste GO:0050909 23 19 0,000 0,06734587 0,09585118 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06734587 0,0957919 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06734587 0,0957327 ! peroxisome organization GO:0007031 29 19 0,000 0,06734587 0,09567357 ! digestive system process GO:0022600 30 19 0,000 0,06734587 0,09561451 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06734587 0,09555553 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06734587 0,09549661 ! response to vitamin A GO:0033189 26 19 0,000 0,06734587 0,09543778 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06734587 0,09537901 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06734587 0,09532031 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06734587 0,09526169 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06734587 0,09520314 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06734587 0,09514466 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06734587 0,09508625 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,06734587 0,09502792 ! cytolysis GO:0019835 20 19 0,000 0,06734587 0,09496966 ! renal system process GO:0003014 35 19 0,000 0,06734587 0,09491146 ! vasodilation GO:0042311 33 19 0,000 0,06734587 0,09485334 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06734587 0,09479529 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,06734587 0,09473731 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06734587 0,09467941 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06734587 0,09462157 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06734587 0,0945638 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,06734587 0,09450611 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06734587 0,09444848 ! sarcomere organization GO:0045214 23 19 0,000 0,06734587 0,09439093 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06734587 0,09433344 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06734587 0,09427602 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06734587 0,09421868 GO:0043450|alkene biosynthetic process, ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06734587 0,0941614 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06734587 0,0941042 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,06734587 0,09404706 ! protein stabilization GO:0050821 26 19 0,000 0,06734587 0,09398999 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,07076395 0,09870048 ! iron ion transport GO:0006826 37 20 0,000 0,07076395 0,09864066 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,07076395 0,09858091 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,07076395 0,09852124 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,07076395 0,09846164 ! response to vitamin GO:0033273 29 20 0,000 0,07076395 0,09840211 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,07076395 0,09834265 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,07076395 0,09828326 ! spinal cord development GO:0021510 31 20 0,000 0,07076395 0,09822395 ! response to ethanol GO:0045471 37 20 0,000 0,07076395 0,09816471 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,07076395 0,09810554 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,07076395 0,09804644 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,07076395 0,09798741 ! chromosome condensation GO:0030261 31 20 0,000 0,07076395 0,09792845 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,07076395 0,09786956 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,07076395 0,09781075 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,07076395 0,097752 ! pallium development GO:0021543 38 20 0,000 0,07076395 0,09769333 ! DNA modification GO:0006304 28 20 0,000 0,07076395 0,09763472 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,07076395 0,09757619 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,07076395 0,09751773 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,07076395 0,09745933 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,07076395 0,09740101 ! collagen catabolic process GO:0030574 25 20 0,000 0,07076395 0,09734275 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,07076395 0,09728457 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,07076395 0,09722645 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,07076395 0,09716841 ! alditol metabolic process GO:0019400 24 20 0,000 0,07076395 0,09711043 ! actin filament-based movement GO:0030048 34 20 0,000 0,07076395 0,09705252 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07416969 0,10166287 ! regulation of cell killing GO:0031341 34 21 0,000 0,07416969 0,10160232 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07416969 0,10154184 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07416969 0,10148144 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07416969 0,1014211 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07416969 0,10136084 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07416969 0,10130065 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07416969 0,10124053 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07416969 0,10118048 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,07416969 0,10112051 ! vesicle docking GO:0048278 27 21 0,000 0,07416969 0,1010606 ! phototransduction GO:0007602 25 21 0,000 0,07416969 0,10100077 ! dendrite development GO:0016358 35 21 0,000 0,07416969 0,100941 ! visual behavior GO:0007632 39 21 0,000 0,07416969 0,10088131 ! ovarian follicle development GO:0001541 30 21 0,000 0,07416969 0,10082169 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07416969 0,10076214 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07416969 0,10070265 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07416969 0,10064324 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07416969 0,1005839 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07416969 0,10052463 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07416969 0,10046543 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07416969 0,1004063 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07416969 0,10034723 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07416969 0,10028824 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07416969 0,10022932 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07416969 0,10017046 ! fatty acid transport GO:0015908 30 21 0,000 0,07416969 0,10011168 ! platelet activation GO:0030168 28 21 0,000 0,07416969 0,10005296 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,07416969 0,09999431 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07416969 0,09993573 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07416969 0,09987722 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07416969 0,09981878 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07416969 0,09976041 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07416969 0,0997021 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07416969 0,09964386 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07416969 0,0995857 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07416969 0,09952759 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07416969 0,09946956 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07416969 0,09941159 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07416969 0,0993537 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07416969 0,09929587 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,07756315 0,1037785 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,07756315 0,10371817 ! viral genome replication GO:0019079 29 22 0,000 0,07756315 0,1036579 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07756315 0,1035977 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07756315 0,10353758 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07756315 0,10347752 ! molting cycle process GO:0022404 40 22 0,000 0,07756315 0,10341753 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07756315 0,10335762 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07756315 0,10329777 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07756315 0,10323799 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07756315 0,10317828 ! vasculogenesis GO:0001570 33 22 0,000 0,07756315 0,10311864 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07756315 0,10305907 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,07756315 0,10299956 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07756315 0,10294013 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,07756315 0,10288076 ! lysosome organization GO:0007040 37 22 0,000 0,07756315 0,10282147 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07756315 0,10276224 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07756315 0,10270308 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07756315 0,10264398 ! regulation of behavior GO:0050795 38 22 0,000 0,07756315 0,10258496 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07756315 0,102526 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07756315 0,10246711 ! membrane depolarization GO:0051899 35 22 0,000 0,07756315 0,10240829 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07756315 0,10234954 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07756315 0,10229085 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,07756315 0,10223223 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07756315 0,10217368 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07756315 0,10211519 ! blastocyst development GO:0001824 37 22 0,000 0,07756315 0,10205678 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07756315 0,10199843 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,08094436 0,10638402 ! neuron fate commitment GO:0048663 32 23 0,000 0,08094436 0,10632326 ! embryonic pattern specification GO:0009880 31 23 0,000 0,08094436 0,10626258 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,08094436 0,10620196 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,08094436 0,10614141 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,08094436 0,10608093 ! vesicle targeting GO:0006903 32 23 0,000 0,08094436 0,10602052 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,08094436 0,10596018 ! osteoblast differentiation GO:0001649 40 23 0,000 0,08094436 0,1058999 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,08094436 0,1058397 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,08094436 0,10577956 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,08094436 0,1057195 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,08094436 0,1056595 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,08094436 0,10559956 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,08094436 0,1055397 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,08094436 0,10547991 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,08094436 0,10542018 ! cell fate determination GO:0001709 45 23 0,000 0,08094436 0,10536052 ! pentose metabolic process GO:0019321 31 23 0,000 0,08094436 0,10530092 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,08094436 0,1052414 ! spermatid development GO:0007286 33 23 0,000 0,08094436 0,10518194 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,08094436 0,10512255 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,08094436 0,10506322 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,08094436 0,10500397 ! telomere organization GO:0032200 32 23 0,000 0,08094436 0,10494478 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,08094436 0,10488565 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,08094436 0,10482659 ! regulation of amine transport GO:0051952 38 23 0,000 0,08094436 0,1047676 ! liver development GO:0001889 40 23 0,000 0,08094436 0,10470868 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08431337 0,10900548 ! initiation of viral infection GO:0019059 42 24 0,000 0,08431337 0,10894425 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08431337 0,10888308 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08431337 0,10882197 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08431337 0,10876094 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,08431337 0,10869998 ! fat cell differentiation GO:0045444 37 24 0,000 0,08431337 0,10863908 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08431337 0,10857825 ! sperm motility GO:0030317 27 24 0,000 0,08431337 0,10851749 ! vacuole organization GO:0007033 39 24 0,000 0,08431337 0,1084568 ! receptor metabolic process GO:0043112 37 24 0,000 0,08431337 0,10839618 ! neural crest cell development GO:0014032 39 24 0,000 0,08431337 0,10833562 GO:0014033|neural crest cell differentiation, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08431337 0,10827513 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08431337 0,10821471 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,08431337 0,10815435 ! glutathione metabolic process GO:0006749 29 24 0,000 0,08431337 0,10809407 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08431337 0,10803385 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08431337 0,1079737 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08431337 0,10791361 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08767023 0,11214768 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08767023 0,11208534 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08767023 0,11202307 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,08767023 0,11196087 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08767023 0,11189873 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08767023 0,11183667 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,08767023 0,11177468 ! peptide transport GO:0015833 43 25 0,000 0,08767023 0,11171275 ! male gonad development GO:0008584 33 25 0,000 0,08767023 0,1116509 ! iron ion homeostasis GO:0055072 39 25 0,000 0,08767023 0,11158911 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08767023 0,11152739 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,08767023 0,11146574 ! phospholipid transport GO:0015914 35 25 0,000 0,08767023 0,11140415 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,08767023 0,11134264 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,08767023 0,11128119 ! detection of light stimulus GO:0009583 30 25 0,000 0,08767023 0,11121981 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,08767023 0,1111585 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,08767023 0,11109726 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,09101496 0,11527226 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,09101496 0,11520882 ! translational initiation GO:0006413 43 26 0,000 0,09101496 0,11514545 ! circadian rhythm GO:0007623 42 26 0,000 0,09101496 0,11508214 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,09101496 0,11501891 ! post-embryonic development GO:0009791 42 26 0,000 0,09101496 0,11495575 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,09101496 0,11489266 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,09101496 0,11482963 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,09101496 0,11476668 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,09101496 0,11470379 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,09101496 0,11464097 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,09101496 0,11457823 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,09101496 0,11451555 ! regulation of coagulation GO:0050818 39 26 0,000 0,09101496 0,11445294 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09434763 0,11857899 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09434763 0,11851423 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09434763 0,11844954 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09434763 0,11838492 ! membrane docking GO:0022406 39 27 0,000 0,09434763 0,11832037 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09434763 0,11825589 ! catechol metabolic process GO:0009712 43 27 0,000 0,09434763 0,11819148 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09434763 0,11812714 ! acute-phase response GO:0006953 42 27 0,000 0,09434763 0,11806287 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09434763 0,11799867 ! myofibril assembly GO:0030239 36 27 0,000 0,09434763 0,11793454 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09434763 0,11787048 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09434763 0,11780649 ! natural killer cell activation GO:0030101 35 27 0,000 0,09434763 0,11774257 ! lipid oxidation GO:0034440 38 27 0,000 0,09434763 0,11767872 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09434763 0,11761493 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09434763 0,11755122 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,09434763 0,11748758 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09434763 0,117424 ! gene silencing GO:0016458 41 27 0,000 0,09434763 0,11736049 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,09766827 0,12142542 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09766827 0,12135982 ! phenol metabolic process GO:0018958 44 28 0,000 0,09766827 0,12129429 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,09766827 0,12122883 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09766827 0,12116344 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09766827 0,12109813 ! cell junction assembly GO:0034329 56 28 0,000 0,09766827 0,12103288 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,09766827 0,1209677 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,09766827 0,1209026 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09766827 0,12083756 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,09766827 0,12077259 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,09766827 0,1207077 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,09766827 0,12064287 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09766827 0,12057811 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09766827 0,12051342 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,09766827 0,12044881 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,09766827 0,12038426 ! mesoderm formation GO:0001707 46 28 0,000 0,09766827 0,12031978 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,09766827 0,12025537 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,09766827 0,12019102 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,09766827 0,12012675 ! BMP signaling pathway GO:0030509 40 28 0,000 0,09766827 0,12006255 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09766827 0,11999841 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09766827 0,11993434 ! placenta development GO:0001890 37 28 0,000 0,09766827 0,11987034 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,10097692 0,12386503 ! regulation of innate immune response GO:0045088 38 29 0,000 0,10097692 0,123799 ! ovulation cycle process GO:0022602 41 29 0,000 0,10097692 0,12373305 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,10097692 0,12366716 ! protein targeting to membrane GO:0006612 53 29 0,000 0,10097692 0,12360134 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,10097692 0,1235356 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,10097692 0,12346992 ! muscle cell development GO:0055001 38 29 0,000 0,10097692 0,12340432 ! formation of primary germ layer GO:0001704 48 29 0,000 0,10097692 0,12333878 ! telencephalon development GO:0021537 52 29 0,000 0,10097692 0,12327332 ! eye morphogenesis GO:0048592 51 29 0,000 0,10097692 0,12320792 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,10097692 0,12314259 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,10427363 0,12709558 ! collagen metabolic process GO:0032963 40 30 0,000 0,10427363 0,12702826 ! organic anion transport GO:0015711 51 30 0,000 0,10427363 0,12696102 ! cholesterol transport GO:0030301 46 30 0,000 0,10427363 0,12689384 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,10427363 0,12682674 ! spliceosome assembly GO:0000245 49 30 0,000 0,10427363 0,1267597 ! spindle organization GO:0007051 37 30 0,000 0,10427363 0,12669274 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,10427363 0,12662585 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,10427363 0,12655903 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,10427363 0,12649228 ! ceramide metabolic process GO:0006672 43 30 0,000 0,10427363 0,1264256 ! ovulation cycle GO:0042698 43 30 0,000 0,10427363 0,12635899 ! hindbrain development GO:0030902 45 30 0,000 0,10427363 0,12629245 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,10427363 0,12622598 ! adult locomotory behavior GO:0008344 47 30 0,000 0,10427363 0,12615958 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,10427363 0,12609325 ! response to heat GO:0009408 41 30 0,000 0,10427363 0,12602699 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,10427363 0,1259608 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,10427363 0,12589468 ! glial cell differentiation GO:0010001 55 31 0,000 0,10755844 0,12979246 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10755844 0,12972439 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,10755844 0,1296564 ! odontogenesis GO:0042476 50 31 0,000 0,10755844 0,12958849 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,10755844 0,12952064 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,10755844 0,12945286 ! metanephros development GO:0001656 58 31 0,000 0,10755844 0,12938516 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10755844 0,12931752 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,10755844 0,12924996 ! cell fate specification GO:0001708 37 31 0,000 0,10755844 0,12918246 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,10755844 0,12911504 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10755844 0,12904769 ! RNA modification GO:0009451 40 31 0,000 0,10755844 0,12898041 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,11083139 0,13283596 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,11083139 0,13276677 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,11083139 0,13269766 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,11083139 0,13262862 ! regulation of protein stability GO:0031647 48 32 0,000 0,11083139 0,13255965 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,11083139 0,13249075 ! cytokine production GO:0001816 44 32 0,000 0,11083139 0,13242192 ! vesicle localization GO:0051648 47 32 0,000 0,11083139 0,13235317 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,11409253 0,13617686 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,11409253 0,13610623 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11409253 0,13603567 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11409253 0,13596519 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,11409253 0,13589478 ! sister chromatid segregation GO:0000819 46 33 0,000 0,11409253 0,13582444 ! ear morphogenesis GO:0042471 42 33 0,000 0,11409253 0,13575417 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11409253 0,13568398 ! cell junction organization GO:0034330 63 33 0,000 0,11409253 0,13561386 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11409253 0,13554381 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11409253 0,13547383 ! nucleus organization GO:0006997 49 33 0,000 0,11409253 0,13540393 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,11409253 0,1353341 ! female gonad development GO:0008585 49 33 0,000 0,11409253 0,13526434 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,11409253 0,13519465 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11409253 0,13512503 ! lipid homeostasis GO:0055088 55 33 0,000 0,11409253 0,13505549 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11409253 0,13498602 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11409253 0,13491661 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11409253 0,13484728 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,11409253 0,13477802 ! cytokinesis GO:0000910 52 33 0,000 0,11409253 0,13470884 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11409253 0,13463972 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,11734189 0,13840325 ! mRNA catabolic process GO:0006402 48 34 0,000 0,11734189 0,13833231 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,11734189 0,13826145 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,11734189 0,13819065 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,11734189 0,13811993 ! feeding behavior GO:0007631 45 34 0,000 0,11734189 0,13804928 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11734189 0,1379787 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,11734189 0,1379082 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,11734189 0,13783776 ! female gamete generation GO:0007292 43 34 0,000 0,11734189 0,1377674 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11734189 0,13769711 ! polyol metabolic process GO:0019751 44 34 0,000 0,11734189 0,1376269 ! aerobic respiration GO:0009060 47 34 0,000 0,11734189 0,13755675 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,11734189 0,13748667 ! embryonic organ development GO:0048568 45 34 0,000 0,11734189 0,13741667 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,11734189 0,13734674 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,12057951 0,14106454 ! Notch signaling pathway GO:0007219 56 35 0,000 0,12057951 0,14099282 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,12057951 0,14092118 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,12057951 0,14084961 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,12057951 0,14077811 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,12057951 0,14070669 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,12057951 0,14063534 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,12057951 0,14056406 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,12057951 0,14049285 ! glycogen metabolic process GO:0005977 48 35 0,000 0,12057951 0,14042171 ! pigment metabolic process GO:0042440 61 35 0,000 0,12057951 0,14035065 ! protein homooligomerization GO:0051260 52 35 0,000 0,12057951 0,14027966 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12380545 0,14395983 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12380545 0,14388708 ! negative regulation of binding GO:0051100 58 36 0,000 0,12380545 0,14381441 ! tissue remodeling GO:0048771 62 36 0,000 0,12380545 0,14374182 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,12380545 0,14366929 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12380545 0,14359684 ! glucan metabolic process GO:0044042 49 36 0,000 0,12380545 0,14352446 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,12701974 0,14717652 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,12701974 0,14710242 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12701974 0,14702838 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12701974 0,14695443 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,12701974 0,14688054 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12701974 0,14680673 ! amino acid activation GO:0043038 52 37 0,000 0,12701974 0,146733 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12701974 0,14665934 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,13022242 0,15028177 ! gliogenesis GO:0042063 71 38 0,000 0,13022242 0,1502064 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,13022242 0,15013111 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,13022242 0,15005589 ! phagocytosis GO:0006909 60 38 0,000 0,13022242 0,14998075 ! mesenchymal cell development GO:0014031 64 38 0,000 0,13022242 0,14990569 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,13022242 0,1498307 ! maintenance of location in cell GO:0051651 69 38 0,000 0,13022242 0,14975578 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,13341353 0,15334888 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,13341353 0,15327229 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,13341353 0,15319577 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,13341353 0,15311932 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,13341353 0,15304295 ! male sex differentiation GO:0046661 53 39 0,000 0,13341353 0,15296666 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,13341353 0,15289044 ! chromatin remodeling GO:0006338 68 39 0,000 0,13341353 0,1528143 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,13341353 0,15273824 ! JNK cascade GO:0007254 54 39 0,000 0,13341353 0,15266225 ! developmental growth GO:0048589 62 39 0,000 0,13341353 0,15258633 ! cell growth GO:0016049 61 39 0,000 0,13341353 0,1525105 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,13659312 0,15606764 ! response to calcium ion GO:0051592 58 40 0,000 0,13659312 0,15599015 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,13659312 0,15591274 ! regulation of tube size GO:0035150 60 40 0,000 0,13659312 0,1558354 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,13659312 0,15575814 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,13659312 0,15568096 ! peptide metabolic process GO:0006518 56 40 0,000 0,13659312 0,15560385 ! inner ear development GO:0048839 57 40 0,000 0,13659312 0,15552682 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,13659312 0,15544986 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,13659312 0,15537298 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,13659312 0,15529618 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,13659312 0,15521945 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,13976122 0,15874114 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,13976122 0,15866279 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,13976122 0,15858451 ! glucose transport GO:0015758 52 41 0,000 0,13976122 0,15850631 ! endosome transport GO:0016197 71 41 0,000 0,13976122 0,15842819 ! striated muscle contraction GO:0006941 62 41 0,000 0,13976122 0,15835015 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,13976122 0,15827218 ! biopolymer methylation GO:0043414 62 41 0,000 0,13976122 0,15819429 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,13976122 0,15811648 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,14291788 0,16160822 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,14291788 0,1615288 ! cellular component disassembly GO:0022411 64 42 0,000 0,14291788 0,16144947 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,14291788 0,16137021 ! hexose transport GO:0008645 54 42 0,000 0,14291788 0,16129103 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,14291788 0,16121193 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,14291788 0,1611329 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,14291788 0,16105395 ! excretion GO:0007588 63 42 0,000 0,14291788 0,16097508 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,14291788 0,16089629 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,14291788 0,16081757 ! regulation of cell shape GO:0008360 78 42 0,000 0,14291788 0,16073893 ! leukocyte migration GO:0050900 60 43 0,000 0,14606313 0,16419609 ! neuromuscular process GO:0050905 79 43 0,000 0,14606313 0,16411588 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,14606313 0,16403575 ! tRNA processing GO:0008033 49 43 0,000 0,14606313 0,16395569 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,14606313 0,16387571 ! vesicle organization GO:0016050 79 43 0,000 0,14606313 0,16379581 ! methylation GO:0032259 64 43 0,000 0,14606313 0,16371599 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14919703 0,16714718 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,14919703 0,1670658 ! glycolysis GO:0006096 53 44 0,000 0,14919703 0,16698451 ! regulation of ion transport GO:0043269 57 44 0,000 0,14919703 0,16690329 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14919703 0,16682215 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,14919703 0,16674109 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,14919703 0,16666011 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,14919703 0,1665792 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14919703 0,16649838 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,14919703 0,16641763 ! RNA catabolic process GO:0006401 64 45 0,000 0,1523196 0,16981826 ! regulation of translational initiation GO:0006446 64 45 0,000 0,1523196 0,16973598 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,1523196 0,16965379 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,1523196 0,16957167 ! cell recognition GO:0008037 58 45 0,000 0,1523196 0,16948963 ! cell maturation GO:0048469 60 45 0,000 0,1523196 0,16940768 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15543089 0,17278445 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,15543089 0,17270098 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15543089 0,17261759 ! regulation of ossification GO:0030278 71 46 0,000 0,15543089 0,17253428 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,15543089 0,17245106 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,15853093 0,17580576 ! viral infectious cycle GO:0019058 71 47 0,000 0,15853093 0,17572103 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,15853093 0,17563639 ! endocrine system development GO:0035270 83 47 0,000 0,15853093 0,17555183 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15853093 0,17546735 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15853093 0,17538295 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15853093 0,17529863 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,15853093 0,17521439 ! chloride transport GO:0006821 67 48 0,000 0,16161978 0,1785425 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,16161978 0,17845679 ! response to temperature stimulus GO:0009266 62 48 0,000 0,16161978 0,17837116 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,16161978 0,17828561 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,16161978 0,17820014 ! gastrulation GO:0007369 73 48 0,000 0,16161978 0,17811475 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,16161978 0,17802945 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,16161978 0,17794423 ! regulation of endocytosis GO:0030100 63 48 0,000 0,16161978 0,17785909 ! nuclear export GO:0051168 69 48 0,000 0,16161978 0,17777403 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,16161978 0,17768905 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,16469746 0,18098622 ! sensory perception of smell GO:0007608 61 49 0,000 0,16469746 0,18089979 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,16469746 0,18081344 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,16469746 0,18072718 ! RNA elongation GO:0006354 62 49 0,000 0,16469746 0,18064099 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,16469746 0,18055489 ! germ cell development GO:0007281 68 49 0,000 0,16469746 0,18046887 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,16469746 0,18038293 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,16469746 0,18029708 ! cartilage development GO:0051216 70 49 0,000 0,16469746 0,1802113 ! maintenance of location GO:0051235 84 49 0,000 0,16469746 0,18012561 ! regulation of actin filament length GO:0030832 72 50 0,000 0,16776402 0,18339223 ! ear development GO:0043583 72 50 0,000 0,16776402 0,18330511 ! membrane fusion GO:0006944 80 50 0,000 0,16776402 0,18321807 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,16776402 0,18313111 ! proton transport GO:0015992 75 50 0,000 0,16776402 0,18304424 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16776402 0,18295745 ! hydrogen transport GO:0006818 77 51 0,000 0,1708195 0,18620135 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,1708195 0,18611315 ! adult behavior GO:0030534 80 51 0,000 0,1708195 0,18602503 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,1708195 0,18593699 ! transition metal ion transport GO:0000041 74 52 0,000 0,17386394 0,18916133 ! regulation of cellular component size GO:0032535 74 52 0,000 0,17386394 0,18907189 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,17386394 0,18898254 ! establishment of organelle localization GO:0051656 85 52 0,000 0,17386394 0,18889327 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,17689737 0,19209818 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,17689737 0,19200753 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,17689737 0,19191696 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,17689737 0,19182647 ! kidney development GO:0001822 90 53 0,000 0,17689737 0,19173607 ! single fertilization GO:0007338 59 53 0,000 0,17689737 0,19164576 ! cell projection assembly GO:0030031 76 53 0,000 0,17689737 0,19155553 ! amino acid transport GO:0006865 84 54 0,000 0,17991983 0,19473676 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,17991983 0,19464516 ! regulation of mitosis GO:0007088 84 54 0,000 0,17991983 0,19455365 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,17991983 0,19446223 ! DNA catabolic process GO:0006308 67 54 0,000 0,17991983 0,19437089 ! detection of external stimulus GO:0009581 66 54 0,000 0,17991983 0,19427963 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,17991983 0,19418847 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17991983 0,19409738 ! exocytosis GO:0006887 74 55 0,000 0,18293138 0,19725371 ! mesoderm development GO:0007498 76 55 0,000 0,18293138 0,19716128 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,18293138 0,19706893 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,18293138 0,19697667 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,18593203 0,20011402 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,18593203 0,20002042 ! carbohydrate transport GO:0008643 74 57 0,000 0,18892183 0,20314176 ! chromosome segregation GO:0007059 83 57 0,000 0,18892183 0,20304683 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18892183 0,20295199 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18892183 0,20285725 ! camera-type eye development GO:0043010 88 57 0,000 0,18892183 0,20276259 ! secondary metabolic process GO:0019748 84 57 0,000 0,18892183 0,20266801 ! developmental maturation GO:0021700 75 57 0,000 0,18892183 0,20257353 ! gonad development GO:0008406 79 57 0,000 0,18892183 0,20247913 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,19190083 0,20557611 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,19190083 0,20548041 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,19190083 0,20538479 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,19486906 0,20846457 ! actin filament organization GO:0007015 95 59 0,000 0,19486906 0,20836766 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,19486906 0,20827083 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,19486906 0,2081741 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,19782655 0,2112354 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,19782655 0,21113738 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,19782655 0,21103945 ! regulation of heart contraction GO:0008016 91 60 0,000 0,19782655 0,21094161 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,19782655 0,21084386 ! fertilization GO:0009566 68 60 0,000 0,19782655 0,21074621 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,19782655 0,21064864 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,20077334 0,2136875 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,20077334 0,21358866 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,20077334 0,21348992 ! urogenital system development GO:0001655 101 61 0,000 0,20077334 0,21339126 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,20077334 0,2132927 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,20077334 0,21319423 ! extracellular matrix organization GO:0030198 103 61 0,000 0,20077334 0,21309584 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,20077334 0,21299755 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,20077334 0,21289935 ! amine catabolic process GO:0009310 90 62 0,000 0,20370948 0,21591328 ! neurotransmitter transport GO:0006836 81 62 0,000 0,20370948 0,21581383 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,20370948 0,21571446 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,20370948 0,21561519 ! organelle localization GO:0051640 96 62 0,000 0,20370948 0,21551601 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,20663501 0,21851058 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,20663501 0,21841016 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,20954995 0,22138947 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20954995 0,22128782 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,20954995 0,22118627 ! hexose catabolic process GO:0019320 82 64 0,000 0,20954995 0,22108481 ! reproductive structure development GO:0048608 90 65 0,000 0,21245435 0,22404631 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,21245435 0,22394363 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,21245435 0,22384104 ! defense response to bacterium GO:0042742 73 65 0,000 0,21245435 0,22373855 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,21245435 0,22363615 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,21245435 0,22353385 ! activation of immune response GO:0002253 83 65 0,000 0,21245435 0,22343164 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,21534824 0,22637155 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,21534824 0,22626814 ! antigen processing and presentation GO:0019882 96 66 0,000 0,21534824 0,22616482 ! regulation of immune effector process GO:0002697 101 66 0,000 0,21534824 0,22606159 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,21823166 0,22898395 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,21823166 0,22887954 ! acute inflammatory response GO:0002526 92 68 0,000 0,22110466 0,23178701 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,22110466 0,23168142 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,22110466 0,23157591 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,22110466 0,23147051 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,22110466 0,2313652 ! rhythmic process GO:0048511 105 68 0,000 0,22110466 0,23125999 ! inorganic anion transport GO:0015698 93 68 0,000 0,22110466 0,23115487 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,22396725 0,2340412 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,22396725 0,23393492 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,22396725 0,23382873 ! response to metal ion GO:0010038 103 70 0,000 0,2268195 0,23669911 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,2268195 0,23659177 ! humoral immune response GO:0006959 86 70 0,000 0,2268195 0,23648452 ! eye development GO:0001654 111 70 0,000 0,2268195 0,23637736 ! amine transport GO:0015837 101 70 0,000 0,2268195 0,23627031 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,2268195 0,23616335 ! muscle cell differentiation GO:0042692 104 71 0,000 0,22966142 0,23901415 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22966142 0,23890604 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,22966142 0,23879804 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22966142 0,23869013 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,23249306 0,24152395 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,23249306 0,24141491 ! regulation of blood pressure GO:0008217 107 73 0,000 0,23531445 0,24423431 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,23531445 0,24412415 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,23531445 0,24401408 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,23812563 0,24681792 ! digestion GO:0007586 97 74 0,000 0,23812563 0,24670674 ! blood coagulation GO:0007596 116 75 0,000 0,24092664 0,2494963 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,24092664 0,24938401 ! response to nutrient GO:0007584 104 75 0,000 0,24092664 0,24927183 ! regulation of ligase activity GO:0051340 114 75 0,000 0,24092664 0,24915975 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,24092664 0,24904776 ! amine biosynthetic process GO:0009309 97 76 0,000 0,24371751 0,25181953 ! tRNA metabolic process GO:0006399 95 76 0,000 0,24371751 0,25170646 ! response to unfolded protein GO:0006986 99 76 0,000 0,24371751 0,25159348 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,24371751 0,25148061 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,24649828 0,2542359 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,24649828 0,25412194 ! sex differentiation GO:0007548 105 77 0,000 0,24649828 0,25400809 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,24649828 0,25389434 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,24649828 0,25378069 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,24926899 0,25651842 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,24926899 0,2564037 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,24926899 0,25628908 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,25202966 0,25901172 ! cellular respiration GO:0045333 107 79 0,000 0,25202966 0,25889604 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,25202966 0,25878046 ! regulation of lyase activity GO:0051339 133 79 0,000 0,25202966 0,25866498 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,25202966 0,25854961 ! chromatin assembly GO:0031497 102 80 0,000 0,25478034 0,26125492 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,25478034 0,2611385 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,25478034 0,26102218 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,25478034 0,26090596 ! forebrain development GO:0030900 131 80 0,000 0,25478034 0,26078985 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,25752107 0,26347796 ! hemostasis GO:0007599 125 81 0,000 0,25752107 0,26336081 ! mRNA transport GO:0051028 121 81 0,000 0,25752107 0,26324376 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,25752107 0,26312681 ! response to protein stimulus GO:0051789 111 81 0,000 0,25752107 0,26300997 ! regulation of neurological system process GO:0031644 122 81 0,000 0,25752107 0,26289323 ! vitamin metabolic process GO:0006766 103 81 0,000 0,25752107 0,2627766 ! detection of stimulus GO:0051606 108 82 0,000 0,26025187 0,26544536 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,26297278 0,26810168 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,26297278 0,26798289 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,26568384 0,2706257 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,26568384 0,2705059 ! sterol metabolic process GO:0016125 120 84 0,000 0,26568384 0,27038621 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,26838508 0,27301446 ! rRNA metabolic process GO:0016072 107 85 0,000 0,26838508 0,27289376 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,26838508 0,27277317 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,26838508 0,27265269 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,27107654 0,27526536 ! nucleosome organization GO:0034728 114 87 0,000 0,27375826 0,27786584 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,27375826 0,27774327 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,27375826 0,27762081 ! female pregnancy GO:0007565 130 87 0,000 0,27375826 0,27749846 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,27643026 0,28008352 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,27643026 0,27996019 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,27643026 0,27983697 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,27643026 0,27971386 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,27909258 0,28228362 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,27909258 0,28215954 ! RNA localization GO:0006403 135 91 0,000 0,28438834 0,28738716 ! ATP metabolic process GO:0046034 137 91 0,000 0,28438834 0,28726095 ! response to virus GO:0009615 122 91 0,000 0,28438834 0,28713484 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,28702183 0,28966662 ! positive regulation of immune response GO:0050778 121 92 0,000 0,28702183 0,28953957 ! sulfur metabolic process GO:0006790 118 92 0,000 0,28702183 0,28941263 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,28964579 0,29193046 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,28964579 0,29180259 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,28964579 0,29167483 ! electron transport chain GO:0022900 123 94 0,000 0,29226024 0,2941788 ! angiogenesis GO:0001525 149 95 0,000 0,29486522 0,29667104 ! carboxylic acid transport GO:0046942 147 95 0,000 0,29486522 0,29654132 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,29746076 0,29902086 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,29746076 0,29889023 ! protein maturation GO:0051604 129 96 0,000 0,29746076 0,29875971 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,30004689 0,3012256 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,30519107 0,30625631 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,30519107 0,30612275 ! regulation of translation GO:0006417 151 100 0,000 0,30774919 0,30855412 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,30774919 0,30841967 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,30774919 0,30828534 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,30774919 0,30815113 ! divalent metal ion transport GO:0070838 171 100 0,000 0,30774919 0,30801703 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,30774919 0,30788305 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,30774919 0,30774919