pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6864-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! viral genome replication GO:0019079 29 22 5,000 2,97E-09 6,831E-06 ! interphase of mitotic cell cycle GO:0051329 156 86 7,000 5,017E-08 5,77E-05 ! interphase GO:0051325 159 88 7,000 6,017E-08 4,613E-05 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 3,000 8,772E-08 5,044E-05 ! cell growth GO:0016049 61 39 5,000 1,195E-07 5,496E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 4,000 2,89E-07 1,108E-04 ! viral infectious cycle GO:0019058 71 47 5,000 3,781E-07 1,242E-04 ! gland development GO:0048732 148 77 6,000 4,186E-07 1,204E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 6,218E-07 1,589E-04 ! viral reproductive process GO:0022415 87 58 5,000 1,35E-06 3,106E-04 ! regulation of protein ubiquitination GO:0031396 19 15 3,000 1,656E-06 3,462E-04 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 2,000 2,148E-06 4,117E-04 ! G1 phase GO:0051318 27 16 3,000 2,197E-06 3,887E-04 ! viral reproduction GO:0016032 92 63 5,000 2,212E-06 3,634E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 4,000 3,642E-06 5,584E-04 ! positive regulation of protein ubiquitination GO:0031398 8 6 2,000 4,277E-06 6,147E-04 ! prostate gland development GO:0030850 9 6 2,000 4,277E-06 5,786E-04 ! regulation of T cell differentiation GO:0045580 59 41 4,000 4,695E-06 5,999E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 5,973E-06 7,23E-04 ! response to insulin stimulus GO:0032868 63 43 4,000 5,973E-06 6,869E-04 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 7,451E-06 8,16E-04 ! regulation of cell cycle process GO:0010564 122 81 5,000 9,673E-06 1,011E-03 ! regulation of lymphocyte differentiation GO:0045619 69 48 4,000 1,037E-05 1,037E-03 ! middle ear morphogenesis GO:0042474 9 8 2,000 1,187E-05 1,137E-03 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 2,000 1,187E-05 1,092E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,187E-05 1,05E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 1,236E-05 1,053E-03 ! ear development GO:0043583 72 50 4,000 1,271E-05 1,044E-03 ! negative regulation of transcription regulator activity GO:0090048 47 27 3,000 2,013E-05 1,596E-03 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 2,429E-05 1,862E-03 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 2,429E-05 1,802E-03 ! negative regulation of kinase activity GO:0033673 100 58 4,000 2,645E-05 1,901E-03 ! negative regulation of transferase activity GO:0051348 105 61 4,000 3,385E-05 2,359E-03 ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 3,451E-05 2,334E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of transcription factor activity GO:0051090 97 63 4,000 3,962E-05 2,603E-03 GO:0090046|regulation of transcription regulator activity, ! meiosis I GO:0007127 52 32 3,000 4,029E-05 2,574E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 4,000 4,277E-05 2,658E-03 ! RNA export from nucleus GO:0006405 44 33 3,000 4,563E-05 2,762E-03 ! negative regulation of DNA binding GO:0043392 54 33 3,000 4,563E-05 2,691E-03 ! androgen receptor signaling pathway GO:0030521 54 33 3,000 4,563E-05 2,624E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 5,148E-05 2,888E-03 ! endocrine pancreas development GO:0031018 19 13 2,000 5,929E-05 3,247E-03 ! negative regulation of binding GO:0051100 58 36 3,000 6,478E-05 3,465E-03 ! positive regulation of phosphorylation GO:0042327 102 70 4,000 6,596E-05 3,448E-03 ! G1 phase of mitotic cell cycle GO:0000080 23 14 2,000 7,513E-05 3,84E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 4,000 7,552E-05 3,776E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of T cell proliferation GO:0042129 58 38 3,000 8,042E-05 3,935E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 9,35E-05 4,48E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 9,35E-05 4,389E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! inner ear development GO:0048839 57 40 3,000 9,865E-05 4,538E-03 ! regulation of DNA binding GO:0051101 119 77 4,000 1,041E-04 4,696E-03 ! epithelial cell differentiation GO:0030855 55 41 3,000 1,088E-04 4,812E-03 ! positive regulation of protein modification process GO:0031401 107 78 4,000 1,107E-04 4,805E-03 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 1,146E-04 4,88E-03 ! negative regulation of translation GO:0017148 22 16 2,000 1,146E-04 4,791E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 1,438E-04 5,907E-03 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 1,655E-04 6,677E-03 ! pancreas development GO:0031016 26 18 2,000 1,655E-04 6,562E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 1,655E-04 6,45E-03 ! negative regulation of T cell activation GO:0050868 25 18 2,000 1,655E-04 6,343E-03 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 1,664E-04 6,273E-03 ! endocrine system development GO:0035270 83 47 3,000 1,864E-04 6,913E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 1,864E-04 6,804E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! reciprocal meiotic recombination GO:0007131 31 19 2,000 1,956E-04 7,03E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 1,956E-04 6,922E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 1,956E-04 6,817E-03 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 1,956E-04 6,716E-03 ! apoptotic nuclear changes GO:0030262 24 19 2,000 1,956E-04 6,617E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 3,000 2,024E-04 6,745E-03 ! nuclear export GO:0051168 69 48 3,000 2,024E-04 6,649E-03 ! regulation of T cell activation GO:0050863 128 89 4,000 2,065E-04 6,69E-03 ! regulation of angiogenesis GO:0045765 94 49 3,000 2,193E-04 7,006E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 2,662E-04 8,386E-03 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 2,662E-04 8,272E-03 ! platelet activation GO:0030168 28 21 2,000 2,662E-04 8,162E-03 ! regulation of binding GO:0051098 151 95 4,000 2,801E-04 8,477E-03 ! skeletal system morphogenesis GO:0048705 78 53 3,000 2,975E-04 8,887E-03 ! vasculogenesis GO:0001570 33 22 2,000 3,068E-04 9,047E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 3,068E-04 8,933E-03 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 4,000 3,086E-04 8,872E-03 ! regulation of mitosis GO:0007088 84 54 3,000 3,198E-04 9,082E-03 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 3,000 3,198E-04 8,971E-03 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 3,513E-04 9,735E-03 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 3,513E-04 9,619E-03 ! response to molecule of bacterial origin GO:0002237 30 23 2,000 3,513E-04 9,506E-03 ! negative regulation of protein ubiquitination GO:0031397 7 5 1,000 3,599E-04 9,625E-03 ! embryonic camera-type eye development GO:0031076 8 5 1,000 3,599E-04 9,514E-03 GO:0048596|embryonic camera-type eye morphogenesis, ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 3,599E-04 9,406E-03 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 1,000 3,599E-04 9,3E-03 ! response to protozoan GO:0001562 9 5 1,000 3,599E-04 9,197E-03 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 3,599E-04 9,096E-03 ! neutrophil mediated immunity GO:0002446 6 5 1,000 3,599E-04 8,997E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 1,000 3,599E-04 8,9E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 3,599E-04 8,806E-03 ! positive regulation of Rho GTPase activity GO:0032321 9 5 1,000 3,599E-04 8,713E-03 ! positive regulation of chemokine production GO:0032722 7 5 1,000 3,599E-04 8,622E-03 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 4,212E-04 9,987E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 4,522E-04 0,01061332 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of chromosome organization GO:0033044 35 25 2,000 4,522E-04 0,01050612 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 4,522E-04 0,01040106 ! negative regulation of protein modification process GO:0031400 50 26 2,000 5,09E-04 0,01159014 ! meiosis GO:0007126 96 61 3,000 5,109E-04 0,0115207 GO:0051327|M phase of meiotic cell cycle, ! urogenital system development GO:0001655 101 61 3,000 5,109E-04 0,01140885 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 5,377E-04 0,01189116 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 5,377E-04 0,01177791 ! regulation of collagen metabolic process GO:0010712 7 6 1,000 5,377E-04 0,0116668 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 5,377E-04 0,01155776 ! neutrophil homeostasis GO:0001780 6 6 1,000 5,377E-04 0,01145074 ! salivary gland morphogenesis GO:0007435 11 6 1,000 5,377E-04 0,01134569 ! organ or tissue specific immune response GO:0002251 7 6 1,000 5,377E-04 0,01124255 ! negative regulation of B cell activation GO:0050869 9 6 1,000 5,377E-04 0,01114127 ! meiotic cell cycle GO:0051321 97 62 3,000 5,436E-04 0,01116376 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 5,701E-04 0,01160304 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 5,778E-04 0,0116573 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 5,778E-04 0,01155593 ! cell cycle checkpoint GO:0000075 108 64 3,000 6,135E-04 0,01216354 ! mRNA export from nucleus GO:0006406 39 28 2,000 6,357E-04 0,01249598 ! regulation of B cell activation GO:0050864 42 28 2,000 6,357E-04 0,01239009 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 7,498E-04 0,01449158 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 7,498E-04 0,01437082 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 7,498E-04 0,01425205 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 7,498E-04 0,01413523 ! regulation of focal adhesion formation GO:0051893 17 7 1,000 7,498E-04 0,01402031 ! peptidyl-threonine modification GO:0018210 18 7 1,000 7,498E-04 0,01390724 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 1,000 7,498E-04 0,01379598 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 7,498E-04 0,01368649 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 7,498E-04 0,01357872 ! embryonic heart tube development GO:0035050 7 7 1,000 7,498E-04 0,01347264 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 7,498E-04 0,0133682 ! embryonic skeletal system morphogenesis GO:0048704 42 30 2,000 7,809E-04 0,0138157 ! spindle organization GO:0007051 37 30 2,000 7,809E-04 0,01371023 ! negative regulation of cell activation GO:0050866 44 30 2,000 7,809E-04 0,01360637 ! mammary gland development GO:0030879 57 31 2,000 8,608E-04 0,01488531 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 9,958E-04 0,01709128 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 9,958E-04 0,01696467 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 9,958E-04 0,01683993 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 9,958E-04 0,01671701 ! embryonic eye morphogenesis GO:0048048 12 8 1,000 9,958E-04 0,01659588 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 1,000 9,958E-04 0,01647648 ! regulation of Notch signaling pathway GO:0008593 18 8 1,000 9,958E-04 0,01635879 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 9,958E-04 0,01624277 ! positive regulation of Ras GTPase activity GO:0032320 20 8 1,000 9,958E-04 0,01612839 ! induction of an organ GO:0001759 11 8 1,000 9,958E-04 0,0160156 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 9,958E-04 0,01590438 ! myeloid cell homeostasis GO:0002262 8 8 1,000 9,958E-04 0,0157947 ! regulation of telomere maintenance GO:0032204 10 8 1,000 9,958E-04 0,01568651 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 9,958E-04 0,0155798 ! ear morphogenesis GO:0042471 42 33 2,000 1,036E-03 0,01609434 ! nucleus organization GO:0006997 49 33 2,000 1,036E-03 0,01598632 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 1,061E-03 0,01626338 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 1,131E-03 0,01722528 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 1,275E-03 0,01929563 ! positive regulation of GTPase activity GO:0043547 21 9 1,000 1,275E-03 0,01916951 ! myeloid leukocyte mediated immunity GO:0002444 11 9 1,000 1,275E-03 0,01904503 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 1,000 1,275E-03 0,01892216 ! regulation of stress fiber formation GO:0051492 20 9 1,000 1,275E-03 0,01880087 ! epithelial cell development GO:0002064 10 9 1,000 1,275E-03 0,01868112 ! motor axon guidance GO:0008045 14 9 1,000 1,275E-03 0,01856288 ! blastocyst formation GO:0001825 12 9 1,000 1,275E-03 0,01844613 ! natural killer cell mediated immunity GO:0002228 13 9 1,000 1,275E-03 0,01833085 GO:0042267|natural killer cell mediated cytotoxicity, ! defense response to Gram-positive bacterium GO:0050830 10 9 1,000 1,275E-03 0,01821699 ! embryonic placenta development GO:0001892 12 9 1,000 1,275E-03 0,01810454 ! forebrain development GO:0030900 131 80 3,000 1,418E-03 0,02000857 ! hemostasis GO:0007599 125 81 3,000 1,485E-03 0,02082314 ! thyroid gland development GO:0030878 19 10 1,000 1,588E-03 0,02213136 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,588E-03 0,02199804 ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,588E-03 0,02186631 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 1,588E-03 0,02173615 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,588E-03 0,02160754 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 1,588E-03 0,02148043 ! positive regulation of interleukin-6 production GO:0032755 13 10 1,000 1,588E-03 0,02135482 ! salivary gland development GO:0007431 22 10 1,000 1,588E-03 0,02123066 ! positive regulation of acute inflammatory response GO:0002675 14 10 1,000 1,588E-03 0,02110794 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,588E-03 0,02098663 ! regulation of actin filament bundle formation GO:0032231 21 10 1,000 1,588E-03 0,02086671 ! developmental induction GO:0031128 13 10 1,000 1,588E-03 0,02074815 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of cell adhesion GO:0030155 159 83 3,000 1,625E-03 0,02111407 ! transcription initiation GO:0006352 118 85 3,000 1,774E-03 0,02292106 ! JAK-STAT cascade GO:0007259 53 40 2,000 1,819E-03 0,02336753 ! cell cycle arrest GO:0007050 150 86 3,000 1,852E-03 0,02366249 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,933E-03 0,02456088 GO:0000725|recombinational repair, ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,933E-03 0,02442593 ! plasma membrane organization GO:0007009 18 11 1,000 1,933E-03 0,02429245 ! focal adhesion formation GO:0048041 24 11 1,000 1,933E-03 0,02416043 ! mitotic spindle organization GO:0007052 15 11 1,000 1,933E-03 0,02402983 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 1,933E-03 0,02390064 ! regulation of Rho GTPase activity GO:0032319 18 11 1,000 1,933E-03 0,02377283 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,933E-03 0,02364638 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 1,000 1,933E-03 0,02352126 ! leukocyte mediated cytotoxicity GO:0001909 17 11 1,000 1,933E-03 0,02339747 ! establishment of RNA localization GO:0051236 128 88 3,000 2,015E-03 0,02426233 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! cellular component disassembly GO:0022411 64 42 2,000 2,095E-03 0,02509223 ! branching morphogenesis of a tube GO:0048754 72 42 2,000 2,095E-03 0,02496222 ! embryonic skeletal system development GO:0048706 56 42 2,000 2,095E-03 0,02483355 ! activation of caspase activity GO:0006919 65 43 2,000 2,242E-03 0,02644296 ! RNA localization GO:0006403 135 91 3,000 2,278E-03 0,02672589 ! gland morphogenesis GO:0022612 23 12 1,000 2,31E-03 0,02697234 ! positive regulation of cell cycle GO:0045787 77 45 2,000 2,555E-03 0,02968277 ! regulation of chemokine production GO:0032642 17 13 1,000 2,72E-03 0,03143144 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 1,000 2,72E-03 0,03127428 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 1,000 2,72E-03 0,03111869 ! exocrine system development GO:0035272 27 13 1,000 2,72E-03 0,03096463 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 2,72E-03 0,0308121 ! regulation of acute inflammatory response GO:0002673 19 13 1,000 2,72E-03 0,03066106 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 2,72E-03 0,03051149 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 3,000 2,766E-03 0,03088532 ! negative regulation of immune system process GO:0002683 73 47 2,000 2,894E-03 0,03216094 ! positive regulation of caspase activity GO:0043280 72 48 2,000 3,074E-03 0,0339909 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 2,000 3,074E-03 0,03382826 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 3,000 3,092E-03 0,03386039 ! regulation of S phase GO:0033261 18 14 1,000 3,16E-03 0,03444803 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 3,16E-03 0,03428554 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 3,16E-03 0,03412457 ! DNA unwinding during replication GO:0006268 21 14 1,000 3,16E-03 0,03396511 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 3,16E-03 0,03380713 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 3,16E-03 0,03365062 ! cell killing GO:0001906 20 14 1,000 3,16E-03 0,03349555 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 3,16E-03 0,0333419 ! peptide hormone secretion GO:0030072 23 14 1,000 3,16E-03 0,03318965 ! regulation of translation GO:0006417 151 100 3,000 3,206E-03 0,0335132 ! regulation of body fluid levels GO:0050878 154 100 3,000 3,206E-03 0,03336155 ! morphogenesis of a branching structure GO:0001763 86 49 2,000 3,26E-03 0,03377614 ! negative regulation of hormone secretion GO:0046888 20 15 1,000 3,632E-03 0,03746048 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 3,632E-03 0,03729324 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 3,632E-03 0,0371275 ! regulation of muscle cell differentiation GO:0051147 24 15 1,000 3,632E-03 0,03696321 ! regulation of survival gene product expression GO:0045884 20 15 1,000 3,632E-03 0,03680038 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 3,632E-03 0,03663898 ! peptide secretion GO:0002790 27 15 1,000 3,632E-03 0,03647898 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 3,632E-03 0,03632038 ! defense response to virus GO:0051607 27 15 1,000 3,632E-03 0,03616314 ! positive regulation of cell migration GO:0030335 92 51 2,000 3,653E-03 0,03621388 ! hormone secretion GO:0046879 25 16 1,000 4,135E-03 0,04081299 ! cellular response to unfolded protein GO:0034620 19 16 1,000 4,135E-03 0,04063858 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of dephosphorylation GO:0035303 33 16 1,000 4,135E-03 0,04046565 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 4,135E-03 0,04029419 ! DNA duplex unwinding GO:0032508 25 17 1,000 4,667E-03 0,04529484 GO:0032392|DNA geometric change, ! cell-substrate junction assembly GO:0007044 39 17 1,000 4,667E-03 0,04510453 ! actin filament bundle formation GO:0051017 26 17 1,000 4,667E-03 0,04491581 ! neuromuscular junction development GO:0007528 23 17 1,000 4,667E-03 0,04472866 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 4,667E-03 0,04454306 ! peptidyl-serine modification GO:0018209 27 17 1,000 4,667E-03 0,044359 ! regulation of immunoglobulin production GO:0002637 25 17 1,000 4,667E-03 0,04417645 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 4,757E-03 0,04484231 ! positive regulation of cell motion GO:0051272 99 56 2,000 4,757E-03 0,04465928 ! positive regulation of translation GO:0045727 28 18 1,000 5,23E-03 0,04889905 ! positive regulation of anti-apoptosis GO:0045768 29 18 1,000 5,23E-03 0,04870107 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 5,23E-03 0,0485047 ! hormone transport GO:0009914 27 18 1,000 5,23E-03 0,0483099 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 5,23E-03 0,04811666 ! lung development GO:0030324 94 59 2,000 5,506E-03 0,05045737 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 5,822E-03 0,05314058 ! response to alkaloid GO:0043279 32 19 1,000 5,822E-03 0,05293054 ! regulation of interleukin-6 production GO:0032675 22 19 1,000 5,822E-03 0,05272215 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 5,822E-03 0,0525154 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 5,822E-03 0,05231026 ! embryonic organ morphogenesis GO:0048562 23 19 1,000 5,822E-03 0,05210672 ! homeostasis of number of cells GO:0048872 84 61 2,000 6,043E-03 0,05387239 ! negative regulation of cell growth GO:0030308 106 62 2,000 6,323E-03 0,05614761 ! respiratory tube development GO:0030323 99 62 2,000 6,323E-03 0,05593166 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 6,444E-03 0,05678469 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 6,444E-03 0,05656796 ! positive regulation of locomotion GO:0040017 35 20 1,000 6,444E-03 0,05635287 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 1,000 6,444E-03 0,05613941 ! positive regulation of osteoblast differentiation GO:0045669 33 20 1,000 6,444E-03 0,05592757 ! positive regulation of B cell activation GO:0050871 31 20 1,000 6,444E-03 0,05571731 ! camera-type eye morphogenesis GO:0048593 34 20 1,000 6,444E-03 0,05550863 ! negative regulation of cell size GO:0045792 108 64 2,000 6,905E-03 0,05925817 ! respiratory system development GO:0060541 100 64 2,000 6,905E-03 0,05903788 ! gluconeogenesis GO:0006094 25 21 1,000 7,094E-03 0,06043131 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 1,000 7,094E-03 0,06020831 ! regulation of chemotaxis GO:0050920 36 21 1,000 7,094E-03 0,05998696 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 7,094E-03 0,05976723 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 7,094E-03 0,0595491 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 7,094E-03 0,05933256 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 7,094E-03 0,05911758 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 7,094E-03 0,05890416 ! positive regulation of protein secretion GO:0050714 26 21 1,000 7,094E-03 0,05869228 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 7,094E-03 0,05848191 ! reproductive structure development GO:0048608 90 65 2,000 7,207E-03 0,05920436 ! regulation of caspase activity GO:0043281 97 65 2,000 7,207E-03 0,05899367 ! regulation of MAPKKK cascade GO:0043408 101 65 2,000 7,207E-03 0,05878447 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 7,773E-03 0,06317148 ! ureteric bud development GO:0001657 32 22 1,000 7,773E-03 0,06294905 ! regulation of behavior GO:0050795 38 22 1,000 7,773E-03 0,06272817 ! leukocyte homeostasis GO:0001776 33 22 1,000 7,773E-03 0,06250884 ! blastocyst development GO:0001824 37 22 1,000 7,773E-03 0,06229104 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 7,836E-03 0,06257964 ! regulation of Ras GTPase activity GO:0032318 110 68 2,000 8,162E-03 0,06495789 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 8,48E-03 0,06725242 ! myelination GO:0042552 35 23 1,000 8,48E-03 0,06702131 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 8,48E-03 0,06679179 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 8,48E-03 0,06656383 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 8,48E-03 0,06633742 ! liver development GO:0001889 40 23 1,000 8,48E-03 0,06611255 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 8,838E-03 0,06867287 ! leukocyte mediated immunity GO:0002443 99 71 2,000 9,188E-03 0,07115085 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 9,188E-03 0,07091209 ! pyruvate metabolic process GO:0006090 29 24 1,000 9,214E-03 0,07087841 ! fat cell differentiation GO:0045444 37 24 1,000 9,214E-03 0,07064215 ! response to toxin GO:0009636 38 24 1,000 9,214E-03 0,07040746 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 9,214E-03 0,07017432 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 9,214E-03 0,06994272 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 9,214E-03 0,06971265 ! regulation of peptidase activity GO:0052547 106 72 2,000 9,546E-03 0,07198315 ! negative regulation of transport GO:0051051 116 73 2,000 9,911E-03 0,07449812 ! tube morphogenesis GO:0035239 118 73 2,000 9,911E-03 0,07425545 ! mitochondrion organization GO:0007005 104 73 2,000 9,911E-03 0,07401436 ! iron ion homeostasis GO:0055072 39 25 1,000 9,976E-03 0,07425579 ! peptide transport GO:0015833 43 25 1,000 9,976E-03 0,07401626 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 9,976E-03 0,07377826 ! positive regulation of nuclear division GO:0051785 39 25 1,000 9,976E-03 0,07354179 GO:0045840|positive regulation of mitosis, ! blood coagulation GO:0007596 116 75 2,000 0,01066756 0,07838783 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 2,000 0,01066756 0,07813818 ! regulation of ligase activity GO:0051340 114 75 2,000 0,01066756 0,07789012 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,01076503 0,07835309 ! regulation of protein transport GO:0051223 114 76 2,000 0,0110578 0,08023009 GO:0070201|regulation of establishment of protein localization, ! inner ear morphogenesis GO:0042472 35 27 1,000 0,01158063 0,08375928 ! acute-phase response GO:0006953 42 27 1,000 0,01158063 0,08349671 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,01158063 0,08323578 ! negative regulation of protein transport GO:0051224 49 27 1,000 0,01158063 0,08297648 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01242255 0,08873251 ! cell junction assembly GO:0034329 56 28 1,000 0,01242255 0,08845779 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,01242255 0,08818477 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,01242255 0,08791344 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 0,01242255 0,08764376 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01242255 0,08737574 GO:0008366|axon ensheathment, ! placenta development GO:0001890 37 28 1,000 0,01242255 0,08710935 ! regulation of GTPase activity GO:0043087 129 80 2,000 0,01270078 0,08878967 ! mRNA transport GO:0051028 121 81 2,000 0,01313217 0,09152723 ! positive regulation of T cell proliferation GO:0042102 44 29 1,000 0,01329045 0,09235057 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01329045 0,0920724 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,01329045 0,09179591 ! eye morphogenesis GO:0048592 51 29 1,000 0,01329045 0,09152107 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 1,000 0,01418399 0,09738263 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,01447622 0,0990932 ! regulation of protein localization GO:0032880 132 85 2,000 0,01494094 0,10197083 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01510283 0,10277077 ! negative regulation of secretion GO:0051048 49 31 1,000 0,01510283 0,10246761 ! metanephros development GO:0001656 58 31 1,000 0,01510283 0,10216624 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01510283 0,10186663 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,01510283 0,10156877 ! cell fate specification GO:0001708 37 31 1,000 0,01510283 0,10127265 ! leukocyte chemotaxis GO:0030595 43 31 1,000 0,01510283 0,10097826 GO:0060326|cell chemotaxis, ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,01604665 0,10697766 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,01604665 0,10666847 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 0,01604665 0,10636107 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01604665 0,10605543 ! regulation of protein stability GO:0031647 48 32 1,000 0,01604665 0,10575155 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,01604665 0,1054494 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,01604665 0,10514898 ! reproductive developmental process GO:0003006 127 89 2,000 0,01688378 0,11032015 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,0170151 0,11086326 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,0170151 0,11055009 ! sister chromatid segregation GO:0000819 46 33 1,000 0,0170151 0,11023868 ! cell junction organization GO:0034330 63 33 1,000 0,0170151 0,10992902 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,0170151 0,1096211 GO:0042593|glucose homeostasis, ! cytokinesis GO:0000910 52 33 1,000 0,0170151 0,10931489 ! response to virus GO:0009615 122 91 2,000 0,01790577 0,1147166 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,01800786 0,11505025 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,01800786 0,11473155 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,01800786 0,11441461 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,01800786 0,11409942 ! embryonic organ development GO:0048568 45 34 1,000 0,01800786 0,11378596 ! cell fate commitment GO:0045165 141 92 2,000 0,01842944 0,11613072 ! DNA recombination GO:0006310 146 92 2,000 0,01842944 0,11581342 ! Notch signaling pathway GO:0007219 56 35 1,000 0,01902462 0,11922784 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,01902462 0,11890385 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01902462 0,11858162 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01902462 0,11826112 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 0,01902462 0,11794236 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02006503 0,12405799 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 1,000 0,02006503 0,1237254 ! in utero embryonic development GO:0001701 147 96 2,000 0,02060888 0,12673908 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,0211288 0,12958994 ! regulation of protein secretion GO:0050708 51 37 1,000 0,0211288 0,12924529 ! amino acid activation GO:0043038 52 37 1,000 0,0211288 0,12890246 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,02221559 0,13517422 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,02221559 0,13481756 ! phagocytosis GO:0006909 60 38 1,000 0,02221559 0,13446278 ! pigmentation GO:0043473 74 38 1,000 0,02221559 0,13410986 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,0233251 0,1404391 ! synapse organization GO:0050808 55 39 1,000 0,0233251 0,14007242 ! response to calcium ion GO:0051592 58 40 1,000 0,02445702 0,14648738 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,02445702 0,14610689 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,02445702 0,14572838 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,02445702 0,14535182 ! double-strand break repair GO:0006302 67 40 1,000 0,02445702 0,1449772 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,02445702 0,14460451 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,02445702 0,14423373 ! glucose transport GO:0015758 52 41 1,000 0,02561105 0,15065321 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02561105 0,15026889 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,02561105 0,14988653 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,02678687 0,15637002 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,02678687 0,15597415 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,02678687 0,15558028 ! hexose transport GO:0008645 54 42 1,000 0,02678687 0,15518839 GO:0015749|monosaccharide transport, ! positive regulation of binding GO:0051099 59 43 1,000 0,02798418 0,16171762 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,02798418 0,16131232 ! leukocyte migration GO:0050900 60 43 1,000 0,02798418 0,16090904 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 0,02798418 0,16050777 ! tRNA processing GO:0008033 49 43 1,000 0,02798418 0,16010849 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,02798418 0,1597112 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,02798418 0,15931588 ! regulation of action potential GO:0001508 71 44 1,000 0,02920269 0,16584245 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,02920269 0,16543397 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,02920269 0,1650275 ! regulation of inflammatory response GO:0050727 60 44 1,000 0,02920269 0,16462302 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,02920269 0,16422052 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02995486 0,16803946 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02995486 0,1676306 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02995486 0,16722373 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02995486 0,16681883 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02995486 0,16641589 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02995486 0,16601488 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02995486 0,16561581 ! sleep GO:0030431 11 5 0,000 0,02995486 0,16521865 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02995486 0,16482339 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02995486 0,16443002 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02995486 0,16403852 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02995486 0,16364888 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02995486 0,16326108 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02995486 0,16287512 ! tongue development GO:0043586 6 5 0,000 0,02995486 0,16249098 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02995486 0,16210865 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02995486 0,16172812 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02995486 0,16134936 ! cobalt ion transport GO:0006824 9 5 0,000 0,02995486 0,16097238 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02995486 0,16059715 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02995486 0,16022367 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02995486 0,15985192 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02995486 0,15948189 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02995486 0,15911357 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02995486 0,15874695 ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02995486 0,15838202 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02995486 0,15801876 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02995486 0,15765716 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02995486 0,15729721 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02995486 0,1569389 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02995486 0,15658222 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02995486 0,15622716 ! malate metabolic process GO:0006108 7 5 0,000 0,02995486 0,1558737 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02995486 0,15552184 ! behavioral response to pain GO:0048266 7 5 0,000 0,02995486 0,15517157 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02995486 0,15482287 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02995486 0,15447573 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02995486 0,15413015 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02995486 0,15378611 ! mating behavior GO:0007617 6 5 0,000 0,02995486 0,1534436 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02995486 0,15310262 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02995486 0,15276314 ! rhythmic behavior GO:0007622 12 5 0,000 0,02995486 0,15242517 ! copulation GO:0007620 7 5 0,000 0,02995486 0,15208869 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02995486 0,15175369 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02995486 0,15142017 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02995486 0,15108811 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02995486 0,1507575 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02995486 0,15042833 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02995486 0,1501006 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02995486 0,1497743 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02995486 0,14944941 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02995486 0,14912592 ! lymph vessel development GO:0001945 7 5 0,000 0,02995486 0,14880384 ! endochondral ossification GO:0001958 12 5 0,000 0,02995486 0,14848314 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02995486 0,14816382 ! parathyroid gland development GO:0060017 8 5 0,000 0,02995486 0,14784587 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02995486 0,14752929 ! anagen GO:0042640 6 5 0,000 0,02995486 0,14721405 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02995486 0,14690016 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02995486 0,14658761 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02995486 0,14627638 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02995486 0,14596648 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02995486 0,14565788 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02995486 0,14535058 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02995486 0,14504458 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02995486 0,14473987 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02995486 0,14443643 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02995486 0,14413426 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02995486 0,14383336 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02995486 0,1435337 ! ovulation GO:0030728 6 5 0,000 0,02995486 0,1432353 ! microvillus organization GO:0032528 7 5 0,000 0,02995486 0,14293813 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02995486 0,14264219 ! response to pH GO:0009268 9 5 0,000 0,02995486 0,14234747 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02995486 0,14205397 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02995486 0,14176168 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02995486 0,14147059 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02995486 0,14118069 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02995486 0,14089198 ! polyol catabolic process GO:0046174 7 5 0,000 0,02995486 0,14060444 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02995486 0,14031808 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02995486 0,14003288 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02995486 0,13974884 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02995486 0,13946595 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02995486 0,1391842 ! urea metabolic process GO:0019627 6 5 0,000 0,02995486 0,13890358 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02995486 0,1386241 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02995486 0,13834574 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02995486 0,13806849 ! neutrophil activation GO:0042119 5 5 0,000 0,02995486 0,13779235 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02995486 0,13751732 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02995486 0,13724338 ! response to food GO:0032094 5 5 0,000 0,02995486 0,13697053 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02995486 0,13669876 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02995486 0,13642807 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02995486 0,13615845 ! forebrain neuron development GO:0021884 7 5 0,000 0,02995486 0,1358899 ! melanosome organization GO:0032438 7 5 0,000 0,02995486 0,1356224 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02995486 0,13535595 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02995486 0,13509054 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02995486 0,13482618 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02995486 0,13456285 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02995486 0,13430054 ! nucleoside transport GO:0015858 6 5 0,000 0,02995486 0,13403926 ! nucleoside salvage GO:0043174 7 5 0,000 0,02995486 0,13377898 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02995486 0,13351972 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02995486 0,13326146 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02995486 0,1330042 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02995486 0,13274793 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02995486 0,13249265 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02995486 0,13223834 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02995486 0,13198501 ! depyrimidination GO:0045008 8 5 0,000 0,02995486 0,13173265 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02995486 0,13148125 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02995486 0,13123081 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02995486 0,13098133 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02995486 0,13073278 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02995486 0,13048518 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02995486 0,13023852 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02995486 0,12999279 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02995486 0,12974798 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02995486 0,12950409 ! monocyte differentiation GO:0030224 8 5 0,000 0,02995486 0,12926112 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02995486 0,12901906 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02995486 0,1287779 ! centrosome duplication GO:0051298 5 5 0,000 0,02995486 0,12853764 ! response to UV-C GO:0010225 6 5 0,000 0,02995486 0,12829828 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02995486 0,12805981 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02995486 0,12782222 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02995486 0,12758551 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02995486 0,12734968 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02995486 0,12711472 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02995486 0,12688062 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02995486 0,12664738 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02995486 0,126415 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02995486 0,12618347 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02995486 0,12595279 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02995486 0,12572295 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02995486 0,12549395 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02995486 0,12526578 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02995486 0,12503843 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02995486 0,12481192 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02995486 0,12458622 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02995486 0,12436133 ! neural tube patterning GO:0021532 6 5 0,000 0,02995486 0,12413726 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02995486 0,12391399 ! histone demethylation GO:0016577 9 5 0,000 0,02995486 0,12369152 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02995486 0,12346985 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02995486 0,12324898 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02995486 0,12302889 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02995486 0,12280959 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02995486 0,12259106 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02995486 0,12237332 ! transcription termination GO:0006353 8 5 0,000 0,02995486 0,12215634 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02995486 0,12194014 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02995486 0,12172469 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02995486 0,12151001 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02995486 0,12129609 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02995486 0,12108291 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02995486 0,12087049 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02995486 0,1206588 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02995486 0,12044786 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02995486 0,12023766 ! apical protein localization GO:0045176 6 5 0,000 0,02995486 0,12002818 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02995486 0,11981944 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02995486 0,11961142 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02995486 0,11940412 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02995486 0,11919754 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02995486 0,11899167 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02995486 0,11878651 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02995486 0,11858206 ! glial cell migration GO:0008347 10 5 0,000 0,02995486 0,11837831 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02995486 0,11817526 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02995486 0,11797291 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02995486 0,11777124 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02995486 0,11757027 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02995486 0,11736998 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02995486 0,11717037 ! neural plate development GO:0001840 6 5 0,000 0,02995486 0,11697144 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02995486 0,11677318 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02995486 0,1165756 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02995486 0,11637868 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02995486 0,11618242 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02995486 0,11598683 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02995486 0,11579189 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02995486 0,11559761 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02995486 0,11540398 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02995486 0,115211 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02995486 0,11501866 ! spindle assembly GO:0051225 5 5 0,000 0,02995486 0,11482696 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02995486 0,1146359 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02995486 0,11444548 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02995486 0,11425568 ! organ regeneration GO:0031100 7 5 0,000 0,02995486 0,11406652 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02995486 0,11387798 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02995486 0,11369006 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02995486 0,11350276 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02995486 0,11331608 GO:0055081|anion homeostasis, ! positive regulation of defense response GO:0031349 59 45 1,000 0,03044211 0,11497019 ! cell maturation GO:0048469 60 45 1,000 0,03044211 0,11478171 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,03044211 0,11459385 ! regulation of ossification GO:0030278 71 46 1,000 0,03170213 0,11914198 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,03170213 0,11894763 ! response to UV GO:0009411 75 46 1,000 0,03170213 0,1187539 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 1,000 0,03298247 0,12334907 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,03428284 0,1280041 ! RNA elongation GO:0006354 62 49 1,000 0,03560295 0,13271765 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,03560295 0,1325029 ! cartilage development GO:0051216 70 49 1,000 0,03560295 0,13228884 ! tRNA transcription GO:0009304 11 6 0,000 0,03583829 0,13294851 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03583829 0,13273442 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03583829 0,13252102 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03583829 0,13230831 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03583829 0,13209628 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03583829 0,13188492 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03583829 0,13167424 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03583829 0,13146424 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03583829 0,1312549 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03583829 0,13104623 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03583829 0,13083822 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03583829 0,13063087 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03583829 0,13042417 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03583829 0,13021813 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03583829 0,13001274 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03583829 0,12980799 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03583829 0,12960389 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03583829 0,12940043 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03583829 0,12919761 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03583829 0,12899543 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,03583829 0,12879387 ! neuron adhesion GO:0007158 9 6 0,000 0,03583829 0,12859294 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,03583829 0,12839264 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03583829 0,12819297 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03583829 0,12799391 ! signal peptide processing GO:0006465 8 6 0,000 0,03583829 0,12779547 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03583829 0,12759764 ! mRNA stabilization GO:0048255 15 6 0,000 0,03583829 0,12740043 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03583829 0,12720382 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03583829 0,12700782 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03583829 0,12681243 ! opsonization GO:0008228 8 6 0,000 0,03583829 0,12661763 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03583829 0,12642343 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03583829 0,12622983 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03583829 0,12603681 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03583829 0,12584439 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03583829 0,12565256 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03583829 0,1254613 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03583829 0,12527063 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03583829 0,12508054 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03583829 0,12489103 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03583829 0,12470208 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03583829 0,12451371 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03583829 0,12432591 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03583829 0,12413867 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03583829 0,12395199 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03583829 0,12376588 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03583829 0,12358032 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03583829 0,12339532 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03583829 0,12321088 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03583829 0,12302698 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03583829 0,12284363 ! thymic T cell selection GO:0045061 12 6 0,000 0,03583829 0,12266083 ! protein lipoylation GO:0009249 10 6 0,000 0,03583829 0,12247857 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03583829 0,12229685 ! pigment granule organization GO:0048753 11 6 0,000 0,03583829 0,12211567 ! drug transport GO:0015893 6 6 0,000 0,03583829 0,12193502 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03583829 0,12175491 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03583829 0,12157533 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03583829 0,12139628 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03583829 0,12121776 ! histidine metabolic process GO:0006547 6 6 0,000 0,03583829 0,12103976 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03583829 0,12086228 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03583829 0,12068532 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03583829 0,12050888 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03583829 0,12033296 ! adenohypophysis development GO:0021984 10 6 0,000 0,03583829 0,12015755 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03583829 0,11998264 ! hyperosmotic response GO:0006972 8 6 0,000 0,03583829 0,11980825 ! microtubule nucleation GO:0007020 10 6 0,000 0,03583829 0,11963436 ! ER overload response GO:0006983 7 6 0,000 0,03583829 0,11946098 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03583829 0,1192881 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03583829 0,11911572 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03583829 0,11894383 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03583829 0,11877244 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03583829 0,11860155 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,03583829 0,11843114 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03583829 0,11826123 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03583829 0,1180918 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03583829 0,11792286 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03583829 0,1177544 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03583829 0,11758641 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03583829 0,11741891 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03583829 0,11725189 ! neuron apoptosis GO:0051402 8 6 0,000 0,03583829 0,11708534 ! organic alcohol transport GO:0015850 9 6 0,000 0,03583829 0,11691926 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03583829 0,11675365 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03583829 0,11658851 ! male sex determination GO:0030238 9 6 0,000 0,03583829 0,11642384 ! carnitine transport GO:0015879 8 6 0,000 0,03583829 0,11625963 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03583829 0,11609588 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03583829 0,1159326 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03583829 0,11576977 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03583829 0,1156074 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03583829 0,11544549 ! parturition GO:0007567 12 6 0,000 0,03583829 0,11528402 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03583829 0,11512301 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03583829 0,11496245 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03583829 0,11480234 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03583829 0,11464267 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03583829 0,11448344 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03583829 0,11432466 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03583829 0,11416631 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03583829 0,1140084 ! macrophage differentiation GO:0030225 10 6 0,000 0,03583829 0,11385093 ! astrocyte development GO:0014002 14 6 0,000 0,03583829 0,1136939 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03583829 0,1135373 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03583829 0,11338112 ! interaction with symbiont GO:0051702 8 6 0,000 0,03583829 0,11322538 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03583829 0,11307006 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03583829 0,11291517 ! eating behavior GO:0042755 6 6 0,000 0,03583829 0,11276071 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03583829 0,11260666 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03583829 0,11245304 ! response to copper ion GO:0046688 9 6 0,000 0,03583829 0,11229983 ! DNA topological change GO:0006265 8 6 0,000 0,03583829 0,11214704 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03583829 0,11199467 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03583829 0,11184271 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03583829 0,11169116 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03583829 0,11154002 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03583829 0,11138929 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03583829 0,11123897 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03583829 0,11108905 ! gas homeostasis GO:0033483 11 6 0,000 0,03583829 0,11093954 ! hair follicle maturation GO:0048820 7 6 0,000 0,03583829 0,11079043 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03583829 0,11064171 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03583829 0,1104934 ! Schwann cell development GO:0014044 14 6 0,000 0,03583829 0,11034548 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03583829 0,11019796 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03583829 0,11005084 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03583829 0,1099041 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03583829 0,10975776 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03583829 0,1096118 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03583829 0,10946624 ! histone ubiquitination GO:0016574 7 6 0,000 0,03583829 0,10932106 ! regulation of meiosis GO:0040020 10 6 0,000 0,03583829 0,10917626 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03583829 0,10903185 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03583829 0,10888782 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03583829 0,10874416 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03583829 0,10860089 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03583829 0,108458 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03583829 0,10831548 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03583829 0,10817333 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03583829 0,10803156 ! receptor internalization GO:0031623 9 6 0,000 0,03583829 0,10789015 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03583829 0,10774912 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03583829 0,10760846 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 8 6 0,000 0,03583829 0,10746816 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03583829 0,10732822 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03583829 0,10718866 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03583829 0,10704945 ! axonal fasciculation GO:0007413 9 6 0,000 0,03583829 0,10691061 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03583829 0,10677212 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03583829 0,10663399 ! midbrain development GO:0030901 6 6 0,000 0,03583829 0,10649622 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03583829 0,10635881 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03583829 0,10622175 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03583829 0,10608504 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03583829 0,10594868 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03583829 0,10581268 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03583829 0,10567702 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03583829 0,10554171 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03583829 0,10540675 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03583829 0,10527213 ! adult feeding behavior GO:0008343 6 6 0,000 0,03583829 0,10513785 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03583829 0,10500392 ! blastocyst growth GO:0001832 15 6 0,000 0,03583829 0,10487033 ! pigment granule transport GO:0051904 12 6 0,000 0,03583829 0,10473707 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03583829 0,10460416 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03583829 0,10447158 ! catecholamine transport GO:0051937 7 6 0,000 0,03583829 0,10433934 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03583829 0,10420743 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03583829 0,10407585 ! protein prenylation GO:0018342 10 6 0,000 0,03583829 0,10394461 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03583829 0,1038137 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03583829 0,10368312 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03583829 0,10355286 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03583829 0,10342293 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03583829 0,10329333 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,03694253 0,10634271 ! muscle fiber development GO:0048747 74 51 1,000 0,03830129 0,11011622 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,03830129 0,10997874 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,03830129 0,10984161 ! positive regulation of secretion GO:0051047 71 51 1,000 0,03830129 0,10970482 ! aging GO:0007568 79 52 1,000 0,03967896 0,11350946 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,03967896 0,11336846 ! establishment of organelle localization GO:0051656 85 52 1,000 0,03967896 0,1132278 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,04107526 0,11706703 ! kidney development GO:0001822 90 53 1,000 0,04107526 0,11692215 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04168638 0,11851505 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04168638 0,11836873 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04168638 0,11822278 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04168638 0,11807718 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04168638 0,11793195 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04168638 0,11778707 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04168638 0,11764254 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04168638 0,11749837 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,04168638 0,11735456 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04168638 0,11721109 ! reproductive behavior GO:0019098 12 7 0,000 0,04168638 0,11706798 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04168638 0,11692521 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04168638 0,11678279 ! oligopeptide transport GO:0006857 11 7 0,000 0,04168638 0,11664072 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04168638 0,116499 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04168638 0,11635761 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04168638 0,11621657 ! RNA methylation GO:0001510 11 7 0,000 0,04168638 0,11607588 ! pericardium development GO:0060039 8 7 0,000 0,04168638 0,11593552 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04168638 0,1157955 ! fibril organization GO:0043206 13 7 0,000 0,04168638 0,11565582 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,04168638 0,11551647 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04168638 0,11537746 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04168638 0,11523879 ! lipoprotein transport GO:0042953 9 7 0,000 0,04168638 0,11510045 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04168638 0,11496244 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04168638 0,11482476 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04168638 0,11468741 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04168638 0,11455039 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04168638 0,11441369 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04168638 0,11427732 ! chemosensory behavior GO:0007635 9 7 0,000 0,04168638 0,11414128 ! microtubule bundle formation GO:0001578 8 7 0,000 0,04168638 0,11400556 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,04168638 0,11387016 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04168638 0,11373508 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04168638 0,11360032 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04168638 0,11346589 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04168638 0,11333176 ! reflex GO:0060004 12 7 0,000 0,04168638 0,11319796 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04168638 0,11306447 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04168638 0,1129313 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04168638 0,11279844 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04168638 0,11266589 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,04168638 0,11253365 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04168638 0,11240173 ! spinal cord patterning GO:0021511 7 7 0,000 0,04168638 0,11227011 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,04168638 0,1121388 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04168638 0,1120078 ! adrenal gland development GO:0030325 17 7 0,000 0,04168638 0,1118771 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04168638 0,11174671 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04168638 0,11161662 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04168638 0,11148683 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04168638 0,11135734 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04168638 0,11122816 ! endosome organization GO:0007032 10 7 0,000 0,04168638 0,11109927 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04168638 0,11097069 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04168638 0,1108424 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04168638 0,1107144 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,04168638 0,1105867 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04168638 0,1104593 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04168638 0,11033219 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04168638 0,11020537 ! galactose metabolic process GO:0006012 10 7 0,000 0,04168638 0,11007884 ! vesicle fusion GO:0006906 15 7 0,000 0,04168638 0,10995261 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04168638 0,10982666 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04168638 0,109701 ! organ growth GO:0035265 11 7 0,000 0,04168638 0,10957563 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04168638 0,10945054 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04168638 0,10932574 ! retinol metabolic process GO:0042572 9 7 0,000 0,04168638 0,10920122 ! behavioral fear response GO:0001662 13 7 0,000 0,04168638 0,10907699 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04168638 0,10895304 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04168638 0,10882937 ! rRNA modification GO:0000154 12 7 0,000 0,04168638 0,10870598 ! protein heterooligomerization GO:0051291 10 7 0,000 0,04168638 0,10858287 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04168638 0,10846004 ! response to UV-B GO:0010224 11 7 0,000 0,04168638 0,10833748 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,04168638 0,10821521 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04168638 0,10809321 ! intermediate filament organization GO:0045109 11 7 0,000 0,04168638 0,10797148 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04168638 0,10785003 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04168638 0,10772885 ! fibrinolysis GO:0042730 9 7 0,000 0,04168638 0,10760794 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,04168638 0,1074873 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04168638 0,10736694 ! B cell lineage commitment GO:0002326 17 7 0,000 0,04168638 0,10724684 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04168638 0,10712701 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04168638 0,10700745 ! response to tropane GO:0014073 13 7 0,000 0,04168638 0,10688815 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04168638 0,10676912 ! melanosome localization GO:0032400 10 7 0,000 0,04168638 0,10665036 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04168638 0,10653186 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04168638 0,10641362 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04168638 0,10629565 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04168638 0,10617793 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04168638 0,10606048 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04168638 0,10594329 ! mast cell activation GO:0045576 9 7 0,000 0,04168638 0,10582635 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04168638 0,10570967 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04168638 0,10559325 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04168638 0,10547709 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04168638 0,10536118 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04168638 0,10524552 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04168638 0,10513012 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04168638 0,10501498 ! T cell lineage commitment GO:0002360 12 7 0,000 0,04168638 0,10490008 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04168638 0,10478544 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04168638 0,10467104 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04168638 0,1045569 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04168638 0,104443 ! response to tumor cell GO:0002347 12 7 0,000 0,04168638 0,10432935 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04168638 0,10421595 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04168638 0,10410279 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04168638 0,10398988 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04168638 0,10387722 ! diuresis GO:0030146 12 7 0,000 0,04168638 0,1037648 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04168638 0,10365262 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,04168638 0,10354068 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04168638 0,10342899 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04168638 0,10331754 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04168638 0,10320632 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04168638 0,10309535 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04168638 0,10298461 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,04168638 0,10287411 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,04168638 0,10276385 ! lymph node development GO:0048535 9 7 0,000 0,04168638 0,10265383 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04168638 0,10254404 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04168638 0,10243448 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04168638 0,10232516 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04168638 0,10221607 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04168638 0,10210721 ! ATP catabolic process GO:0006200 10 7 0,000 0,04168638 0,10199859 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04168638 0,10189019 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04168638 0,10178203 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04168638 0,1016741 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04168638 0,10156639 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04168638 0,10145891 ! muscle adaptation GO:0043500 12 7 0,000 0,04168638 0,10135166 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04168638 0,10124464 GO:0006043|glucosamine catabolic process, ! retina homeostasis GO:0001895 9 7 0,000 0,04168638 0,10113784 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04168638 0,10103127 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04168638 0,10092492 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04168638 0,10081879 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04168638 0,10071289 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04168638 0,10060721 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,04168638 0,10050175 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,04248992 0,10233174 ! detection of external stimulus GO:0009581 66 54 1,000 0,04248992 0,1022247 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,04248992 0,10211788 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,04537324 0,10893367 ! carbohydrate transport GO:0008643 74 57 1,000 0,04684137 0,11234115 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,04684137 0,11222413 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 1,000 0,04684137 0,11210735 ! camera-type eye development GO:0043010 88 57 1,000 0,04684137 0,11199081 ! secondary metabolic process GO:0019748 84 57 1,000 0,04684137 0,11187452 ! developmental maturation GO:0021700 75 57 1,000 0,04684137 0,11175847 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04749933 0,11321083 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04749933 0,11309363 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,04749933 0,11297668 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04749933 0,11285997 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04749933 0,1127435 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04749933 0,11262727 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04749933 0,11251128 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04749933 0,11239553 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,04749933 0,11228001 ! phosphate transport GO:0006817 10 8 0,000 0,04749933 0,11216473 ! N-glycan processing GO:0006491 12 8 0,000 0,04749933 0,11204969 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04749933 0,11193489 ! UTP metabolic process GO:0046051 8 8 0,000 0,04749933 0,11182032 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04749933 0,11170598 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04749933 0,11159188 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,04749933 0,11147801 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04749933 0,11136437 ! succinate metabolic process GO:0006105 14 8 0,000 0,04749933 0,11125097 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,04749933 0,11113779 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04749933 0,11102485 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04749933 0,11091213 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04749933 0,11079965 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04749933 0,11068739 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04749933 0,11057535 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04749933 0,11046355 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04749933 0,11035197 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04749933 0,11024062 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04749933 0,11012949 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04749933 0,11001858 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04749933 0,1099079 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04749933 0,10979744 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04749933 0,1096872 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04749933 0,10957718 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04749933 0,10946739 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04749933 0,10935781 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04749933 0,10924845 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04749933 0,10913931 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04749933 0,10903039 ! melanin metabolic process GO:0006582 12 8 0,000 0,04749933 0,10892169 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04749933 0,1088132 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04749933 0,10870493 ! macrophage activation GO:0042116 12 8 0,000 0,04749933 0,10859687 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04749933 0,10848903 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04749933 0,1083814 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04749933 0,10827398 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04749933 0,10816678 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04749933 0,10805979 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04749933 0,10795301 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04749933 0,10784645 ! ruffle organization GO:0031529 11 8 0,000 0,04749933 0,10774009 ! osteoblast development GO:0002076 13 8 0,000 0,04749933 0,10763394 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04749933 0,107528 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04749933 0,10742227 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04749933 0,10731675 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04749933 0,10721143 GO:0007351|tripartite regional subdivision, ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04749933 0,10710632 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04749933 0,10700142 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04749933 0,10689672 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04749933 0,10679223 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04749933 0,10668794 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04749933 0,10658385 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04749933 0,10647997 ! segment specification GO:0007379 10 8 0,000 0,04749933 0,10637629 ! cellular extravasation GO:0045123 11 8 0,000 0,04749933 0,10627281 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04749933 0,10616953 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04749933 0,10606646 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04749933 0,10596358 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04749933 0,1058609 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04749933 0,10575842 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04749933 0,10565614 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04749933 0,10555406 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04749933 0,10545217 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04749933 0,10535048 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04749933 0,10524899 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04749933 0,10514769 ! icosanoid secretion GO:0032309 12 8 0,000 0,04749933 0,10504659 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04749933 0,10494568 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04749933 0,10484496 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04749933 0,10474444 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04749933 0,10464411 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04749933 0,10454397 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04749933 0,10444403 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04749933 0,10434427 ! sterol catabolic process GO:0016127 9 8 0,000 0,04749933 0,1042447 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04749933 0,10414533 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04749933 0,10404614 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04749933 0,10394715 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04749933 0,10384834 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04749933 0,10374972 ! prophase GO:0051324 11 8 0,000 0,04749933 0,10365128 ! S phase GO:0051320 8 8 0,000 0,04749933 0,10355303 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04749933 0,10345497 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04749933 0,1033571 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04749933 0,10325941 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04749933 0,1031619 ! hormone catabolic process GO:0042447 13 8 0,000 0,04749933 0,10306458 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04749933 0,10296744 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04749933 0,10287048 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04749933 0,10277371 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04749933 0,10267712 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04749933 0,1025807 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04749933 0,10248448 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04749933 0,10238843 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04749933 0,10229256 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04749933 0,10219687 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04749933 0,10210136 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04749933 0,10200602 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04749933 0,10191087 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04749933 0,10181589 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,04832681 0,10349316 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,04982927 0,10661147 ! actin filament organization GO:0007015 95 59 1,000 0,04982927 0,10651239 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,05134853 0,10965795 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,0528843 0,11283293 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,0528843 0,11272836 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,0528843 0,11262398 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,0528843 0,11251979 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,05327734 0,11325128 ! regulation of developmental growth GO:0048638 13 9 0,000 0,05327734 0,11314671 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,05327734 0,11304233 ! telencephalon cell migration GO:0022029 16 9 0,000 0,05327734 0,11293815 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,05327734 0,11283415 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,05327734 0,11273035 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,05327734 0,11262674 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05327734 0,11252331 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,05327734 0,11242008 ! GTP metabolic process GO:0046039 9 9 0,000 0,05327734 0,11231704 ! elastic fiber assembly GO:0048251 13 9 0,000 0,05327734 0,11221418 ! social behavior GO:0035176 14 9 0,000 0,05327734 0,11211152 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,05327734 0,11200904 ! artery development GO:0060840 19 9 0,000 0,05327734 0,11190675 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,05327734 0,11180464 ! regulation of glycolysis GO:0006110 15 9 0,000 0,05327734 0,11170273 ! response to pain GO:0048265 16 9 0,000 0,05327734 0,11160099 ! protein complex disassembly GO:0043241 17 9 0,000 0,05327734 0,11149944 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,05327734 0,11139808 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,05327734 0,1112969 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,05327734 0,11119591 ! lung alveolus development GO:0048286 17 9 0,000 0,05327734 0,1110951 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,05327734 0,11099447 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,05327734 0,11089402 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,05327734 0,11079375 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,05327734 0,11069367 ! ventral spinal cord development GO:0021517 11 9 0,000 0,05327734 0,11059376 ! protein targeting to ER GO:0045047 19 9 0,000 0,05327734 0,11049404 ! T cell selection GO:0045058 18 9 0,000 0,05327734 0,1103945 ! endoderm development GO:0007492 12 9 0,000 0,05327734 0,11029513 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,05327734 0,11019594 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,05327734 0,11009694 ! arginine catabolic process GO:0006527 10 9 0,000 0,05327734 0,10999811 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,05327734 0,10989945 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,05327734 0,10980098 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05327734 0,10970268 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,05327734 0,10960455 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,05327734 0,1095066 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05327734 0,10940883 ! mannose metabolic process GO:0006013 9 9 0,000 0,05327734 0,10931123 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,05327734 0,10921381 ! receptor clustering GO:0043113 15 9 0,000 0,05327734 0,10911655 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,05327734 0,10901948 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,05327734 0,10892257 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,05327734 0,10882583 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,05327734 0,10872927 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,05327734 0,10863288 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,05327734 0,10853666 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,05327734 0,10844061 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,05327734 0,10834473 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,05327734 0,10824902 ! blastoderm segmentation GO:0007350 11 9 0,000 0,05327734 0,10815348 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,05327734 0,1080581 ! DNA ligation GO:0006266 14 9 0,000 0,05327734 0,1079629 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,05327734 0,10786786 ! response to amine stimulus GO:0014075 13 9 0,000 0,05327734 0,10777299 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,05327734 0,10767829 ! erythrocyte development GO:0048821 11 9 0,000 0,05327734 0,10758375 ! renal water homeostasis GO:0003091 14 9 0,000 0,05327734 0,10748938 ! postreplication repair GO:0006301 11 9 0,000 0,05327734 0,10739517 ! mRNA cleavage GO:0006379 13 9 0,000 0,05327734 0,10730113 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,05327734 0,10720725 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,05327734 0,10711354 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,05327734 0,10701999 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,05327734 0,10692661 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,05327734 0,10683338 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,05327734 0,10674032 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,05327734 0,10664742 ! acid secretion GO:0046717 14 9 0,000 0,05327734 0,10655469 ! musculoskeletal movement GO:0050881 11 9 0,000 0,05327734 0,10646211 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,05327734 0,1063697 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,05327734 0,10627744 ! purine base metabolic process GO:0006144 18 9 0,000 0,05327734 0,10618535 ! oocyte differentiation GO:0009994 12 9 0,000 0,05327734 0,10609341 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,05327734 0,10600163 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,05327734 0,10591002 ! spleen development GO:0048536 15 9 0,000 0,05327734 0,10581856 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,05327734 0,10572726 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,05327734 0,10563611 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,05327734 0,10554512 ! detection of calcium ion GO:0005513 13 9 0,000 0,05327734 0,10545429 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,05327734 0,10536362 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,05327734 0,1052731 ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,05327734 0,10518274 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05327734 0,10509253 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,05327734 0,10500248 ! prepulse inhibition GO:0060134 14 9 0,000 0,05327734 0,10491258 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,05327734 0,10482283 ! insulin secretion GO:0030073 17 9 0,000 0,05327734 0,10473324 ! sequestering of metal ion GO:0051238 11 9 0,000 0,05327734 0,1046438 ! response to nicotine GO:0035094 16 9 0,000 0,05327734 0,10455451 ! establishment of cell polarity GO:0030010 12 9 0,000 0,05327734 0,10446538 ! nucleus localization GO:0051647 15 9 0,000 0,05327734 0,1043764 ! regulation of synapse organization GO:0050807 12 9 0,000 0,05327734 0,10428757 ! localization within membrane GO:0051668 15 9 0,000 0,05327734 0,10419889 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,05443636 0,10637521 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,05443636 0,10628491 ! organelle localization GO:0051640 96 62 1,000 0,05443636 0,10619476 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,05758829 0,11224837 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05902064 0,11494282 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05902064 0,11484557 ! neuron fate specification GO:0048665 11 10 0,000 0,05902064 0,11474849 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05902064 0,11465158 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05902064 0,11455483 ! synapsis GO:0007129 13 10 0,000 0,05902064 0,11445824 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05902064 0,11436181 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05902064 0,11426555 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05902064 0,11416944 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05902064 0,1140735 ! sulfate transport GO:0008272 12 10 0,000 0,05902064 0,11397772 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05902064 0,11388211 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,05902064 0,11378665 ! androgen metabolic process GO:0008209 13 10 0,000 0,05902064 0,11369135 ! phospholipid efflux GO:0033700 16 10 0,000 0,05902064 0,11359621 ! hippocampus development GO:0021766 19 10 0,000 0,05902064 0,11350123 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,05902064 0,11340641 ! blood vessel remodeling GO:0001974 21 10 0,000 0,05902064 0,11331174 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05902064 0,11321724 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05902064 0,11312289 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05902064 0,1130287 ! pathogenesis GO:0009405 13 10 0,000 0,05902064 0,11293467 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05902064 0,11284079 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05902064 0,11274707 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,05902064 0,1126535 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,05902064 0,11256009 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05902064 0,11246683 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05902064 0,11237373 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05902064 0,11228079 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05902064 0,11218799 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05902064 0,11209535 ! response to X-ray GO:0010165 16 10 0,000 0,05902064 0,11200286 ! B cell proliferation GO:0042100 14 10 0,000 0,05902064 0,11191053 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05902064 0,11181834 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05902064 0,11172631 ! forebrain cell migration GO:0021885 17 10 0,000 0,05902064 0,11163443 ! lipid digestion GO:0044241 15 10 0,000 0,05902064 0,1115427 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05902064 0,11145112 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05902064 0,1113597 ! UV protection GO:0009650 14 10 0,000 0,05902064 0,11126842 ! entry into host cell GO:0030260 20 10 0,000 0,05902064 0,11117729 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05902064 0,11108631 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05902064 0,11099548 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05902064 0,1109048 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05902064 0,11081426 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,05902064 0,11072387 ! regulation of bone resorption GO:0045124 24 10 0,000 0,05902064 0,11063363 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05902064 0,11054354 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05902064 0,1104536 ! regulation of organ growth GO:0046620 11 10 0,000 0,05902064 0,1103638 ! response to dsRNA GO:0043331 18 10 0,000 0,05902064 0,11027414 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05902064 0,11018463 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05902064 0,11009527 ! embryonic axis specification GO:0000578 12 10 0,000 0,05902064 0,11000605 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05902064 0,10991698 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05902064 0,10982805 ! cranial nerve development GO:0021545 12 10 0,000 0,05902064 0,10973926 ! fucose catabolic process GO:0019317 16 10 0,000 0,05902064 0,10965062 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05902064 0,10956212 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05902064 0,10947377 ! protein sumoylation GO:0016925 12 10 0,000 0,05902064 0,10938555 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05902064 0,10929748 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05902064 0,10920955 ! zymogen activation GO:0031638 14 10 0,000 0,05902064 0,10912176 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05902064 0,10903411 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05902064 0,1089466 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05902064 0,10885924 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05902064 0,10877201 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05902064 0,10868492 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05902064 0,10859798 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05902064 0,10851117 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05902064 0,1084245 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05902064 0,10833796 ! detection of bacterium GO:0016045 10 10 0,000 0,05902064 0,10825157 ! embryonic gut development GO:0048566 11 10 0,000 0,05902064 0,10816531 ! activation of innate immune response GO:0002218 10 10 0,000 0,05902064 0,1080792 GO:0002758|innate immune response-activating signal transduction, ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05902064 0,10799321 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05902064 0,10790737 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,05902064 0,10782166 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05902064 0,10773609 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05902064 0,10765065 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,05918768 0,10786979 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,05918768 0,10778438 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,05918768 0,10769911 ! protein oligomerization GO:0051259 100 65 1,000 0,05918768 0,10761397 ! defense response to bacterium GO:0042742 73 65 1,000 0,05918768 0,10752897 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,06080236 0,11037525 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,06080236 0,1102882 ! axon guidance GO:0007411 99 66 1,000 0,06080236 0,11020129 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,06080236 0,11011452 ! regulation of immune effector process GO:0002697 101 66 1,000 0,06080236 0,11002788 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,0624321 0,11288822 ! acute inflammatory response GO:0002526 92 68 1,000 0,06407664 0,11577084 ! rRNA transcription GO:0009303 17 11 0,000 0,06472942 0,11685845 ! respiratory burst GO:0045730 14 11 0,000 0,06472942 0,1167668 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,06472942 0,11667529 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,06472942 0,11658392 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,06472942 0,1164927 ! virus-host interaction GO:0019048 17 11 0,000 0,06472942 0,11640161 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,06472942 0,11631068 ! filopodium assembly GO:0046847 19 11 0,000 0,06472942 0,11621988 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,06472942 0,11612922 ! RNA polyadenylation GO:0043631 19 11 0,000 0,06472942 0,11603871 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,06472942 0,11594834 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,06472942 0,1158581 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,06472942 0,11576801 ! T cell proliferation GO:0042098 20 11 0,000 0,06472942 0,11567806 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,06472942 0,11558825 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,06472942 0,11549858 ! bone resorption GO:0045453 16 11 0,000 0,06472942 0,11540904 ! regulated secretory pathway GO:0045055 14 11 0,000 0,06472942 0,11531965 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,06472942 0,11523039 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,06472942 0,11514127 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,06472942 0,11505229 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,06472942 0,11496345 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,06472942 0,11487474 ! syncytium formation GO:0006949 15 11 0,000 0,06472942 0,11478617 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,06472942 0,11469774 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,06472942 0,11460944 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,06472942 0,11452128 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,06472942 0,11443325 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,06472942 0,11434536 ! adult heart development GO:0007512 11 11 0,000 0,06472942 0,11425761 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,06472942 0,11416999 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,06472942 0,1140825 ! temperature homeostasis GO:0001659 16 11 0,000 0,06472942 0,11399515 ! L-glutamate transport GO:0015813 16 11 0,000 0,06472942 0,11390793 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,06472942 0,11382084 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,06472942 0,11373389 ! stem cell development GO:0048864 29 11 0,000 0,06472942 0,11364707 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,06472942 0,11356038 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,06472942 0,11347383 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,06472942 0,11338741 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,06472942 0,11330111 ! vasoconstriction GO:0042310 15 11 0,000 0,06472942 0,11321495 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,06472942 0,11312892 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,06472942 0,11304303 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,06472942 0,11295726 ! ribosome assembly GO:0042255 13 11 0,000 0,06472942 0,11287162 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,06472942 0,11278611 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,06472942 0,11270073 ! chromatin silencing GO:0006342 19 11 0,000 0,06472942 0,11261548 ! nucleosome positioning GO:0016584 13 11 0,000 0,06472942 0,11253036 ! T cell homeostasis GO:0043029 20 11 0,000 0,06472942 0,11244537 ! regulation of isotype switching GO:0045191 19 11 0,000 0,06472942 0,1123605 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,06472942 0,11227577 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,06472942 0,11219116 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,06472942 0,11210668 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,06472942 0,11202232 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,06472942 0,11193809 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,06472942 0,11185399 ! male genitalia development GO:0030539 13 11 0,000 0,06472942 0,11177002 ! cholesterol efflux GO:0033344 19 11 0,000 0,06472942 0,11168617 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,06472942 0,11160245 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,06472942 0,11151885 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,06472942 0,11143538 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,06472942 0,11135203 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,06472942 0,11126881 ! defense response to fungus GO:0050832 12 11 0,000 0,06472942 0,11118571 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,06472942 0,11110273 ! lysogeny GO:0030069 18 11 0,000 0,06472942 0,11101988 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,06472942 0,11093716 ! acrosome reaction GO:0007340 13 11 0,000 0,06472942 0,11085455 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,06472942 0,11077207 ! response to drug GO:0042493 108 69 1,000 0,06573576 0,1124106 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,06573576 0,11232709 ! response to metal ion GO:0010038 103 70 1,000 0,06740923 0,11510114 ! humoral immune response GO:0006959 86 70 1,000 0,06740923 0,11501575 ! eye development GO:0001654 111 70 1,000 0,06740923 0,11493049 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,06909681 0,11772049 ! muscle cell differentiation GO:0042692 104 71 1,000 0,06909681 0,11763336 ! lactation GO:0007595 20 12 0,000 0,07040389 0,11976993 ! reproductive cellular process GO:0048610 14 12 0,000 0,07040389 0,11968141 ! tRNA modification GO:0006400 14 12 0,000 0,07040389 0,11959302 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,07040389 0,11950476 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,07040389 0,11941663 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,07040389 0,11932863 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,07040389 0,11924076 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,07040389 0,11915302 ! non-recombinational repair GO:0000726 19 12 0,000 0,07040389 0,1190654 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,07040389 0,11897792 ! peroxisomal transport GO:0043574 21 12 0,000 0,07040389 0,11889056 ! cartilage condensation GO:0001502 18 12 0,000 0,07040389 0,11880334 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,07040389 0,11871624 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,07040389 0,11862927 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,07040389 0,11854242 ! heart looping GO:0001947 15 12 0,000 0,07040389 0,1184557 ! palate development GO:0060021 15 12 0,000 0,07040389 0,11836911 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,07040389 0,11828265 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,07040389 0,11819631 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,07040389 0,1181101 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,07040389 0,11802401 ! arginine metabolic process GO:0006525 13 12 0,000 0,07040389 0,11793805 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,07040389 0,11785222 ! methionine metabolic process GO:0006555 13 12 0,000 0,07040389 0,11776651 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,07040389 0,11768092 ! Golgi organization GO:0007030 18 12 0,000 0,07040389 0,11759546 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,07040389 0,11751012 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,07040389 0,11742491 ! monoamine transport GO:0015844 13 12 0,000 0,07040389 0,11733982 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07040389 0,11725485 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,07040389 0,11717001 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,07040389 0,11708528 ! L-amino acid transport GO:0015807 20 12 0,000 0,07040389 0,11700068 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,07040389 0,11691621 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,07040389 0,11683185 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,07040389 0,11674762 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07040389 0,11666351 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,07040389 0,11657952 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,07040389 0,11649565 ! cerebellum development GO:0021549 13 12 0,000 0,07040389 0,1164119 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,07040389 0,11632827 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,07040389 0,11624476 ! histone acetylation GO:0016573 23 12 0,000 0,07040389 0,11616137 ! histone methylation GO:0016571 15 12 0,000 0,07040389 0,1160781 ! autonomic nervous system development GO:0048483 23 12 0,000 0,07040389 0,11599495 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,07040389 0,11591192 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,07040389 0,115829 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,07040389 0,11574621 ! response to gamma radiation GO:0010332 20 12 0,000 0,07040389 0,11566353 ! regulation of epidermis development GO:0045682 17 12 0,000 0,07040389 0,11558098 ! intestinal absorption GO:0050892 19 12 0,000 0,07040389 0,11549854 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,07040389 0,11541621 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,07040389 0,11533401 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,07040389 0,11525192 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,07040389 0,11516995 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,07040389 0,11508809 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,07040389 0,11500635 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,07040389 0,11492473 ! microspike assembly GO:0030035 23 12 0,000 0,07040389 0,11484323 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,07040389 0,11476183 ! response to cold GO:0009409 14 12 0,000 0,07040389 0,11468056 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,07079827 0,11524135 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,07251339 0,11794965 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,07424195 0,12067596 ! response to inorganic substance GO:0010035 115 75 1,000 0,07598371 0,12341987 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,07604426 0,12343104 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,07604426 0,123344 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,07604426 0,12325707 ! cGMP metabolic process GO:0046068 16 13 0,000 0,07604426 0,12317027 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,07604426 0,1230836 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,07604426 0,12299704 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,07604426 0,1229106 ! lipid localization GO:0010876 24 13 0,000 0,07604426 0,12282429 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,07604426 0,1227381 ! organelle fusion GO:0048284 28 13 0,000 0,07604426 0,12265203 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,07604426 0,12256607 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,07604426 0,12248024 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,07604426 0,12239453 ! response to hexose stimulus GO:0009746 19 13 0,000 0,07604426 0,12230894 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,07604426 0,12222347 ! glutamate metabolic process GO:0006536 18 13 0,000 0,07604426 0,12213812 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,07604426 0,12205289 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,07604426 0,12196777 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,07604426 0,12188278 ! NAD metabolic process GO:0019674 21 13 0,000 0,07604426 0,1217979 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,07604426 0,12171314 ! bone mineralization GO:0030282 15 13 0,000 0,07604426 0,1216285 ! regulation of exocytosis GO:0017157 17 13 0,000 0,07604426 0,12154398 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,07604426 0,12145958 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,07604426 0,12137529 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,07604426 0,12129112 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,07604426 0,12120706 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,07604426 0,12112312 ! genitalia development GO:0048806 15 13 0,000 0,07604426 0,1210393 ! regulation of cellular pH GO:0030641 20 13 0,000 0,07604426 0,12095559 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,07604426 0,120872 ! cellular pigmentation GO:0033059 24 13 0,000 0,07604426 0,12078853 ! tissue regeneration GO:0042246 21 13 0,000 0,07604426 0,12070517 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,07604426 0,12062192 ! cofactor transport GO:0051181 19 13 0,000 0,07604426 0,12053879 ! NADP metabolic process GO:0006739 18 13 0,000 0,07604426 0,12045578 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,07604426 0,12037288 ! gas transport GO:0015669 18 13 0,000 0,07604426 0,12029009 ! regulation of RNA stability GO:0043487 28 13 0,000 0,07604426 0,12020741 ! heme biosynthetic process GO:0006783 20 13 0,000 0,07604426 0,12012485 ! regulation of axon extension GO:0030516 23 13 0,000 0,07604426 0,12004241 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,07604426 0,11996007 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,07604426 0,11987785 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,07604426 0,11979575 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,07604426 0,11971375 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,07604426 0,11963187 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,07604426 0,11955009 ! tRNA metabolic process GO:0006399 95 76 1,000 0,07773847 0,1221301 ! response to unfolded protein GO:0006986 99 76 1,000 0,07773847 0,12204674 ! sex differentiation GO:0007548 105 77 1,000 0,07950599 0,12473655 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,07950599 0,12465152 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,08165072 0,12792688 ! superoxide anion generation GO:0042554 18 14 0,000 0,08165072 0,12783979 ! neuron maturation GO:0042551 21 14 0,000 0,08165072 0,12775283 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,08165072 0,12766598 ! myotube differentiation GO:0014902 21 14 0,000 0,08165072 0,12757925 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,08165072 0,12749264 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,08165072 0,12740614 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,08165072 0,12731977 ! inositol metabolic process GO:0006020 20 14 0,000 0,08165072 0,12723351 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,08165072 0,12714736 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,08165072 0,12706134 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,08165072 0,12697543 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,08165072 0,12688963 ! gene silencing by RNA GO:0031047 20 14 0,000 0,08165072 0,12680395 ! response to cAMP GO:0051591 19 14 0,000 0,08165072 0,12671839 ! limbic system development GO:0021761 25 14 0,000 0,08165072 0,12663294 ! startle response GO:0001964 21 14 0,000 0,08165072 0,12654761 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,08165072 0,12646239 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,08165072 0,12637729 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,08165072 0,1262923 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,08165072 0,12620743 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,08165072 0,12612267 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,08165072 0,12603802 ! glycine metabolic process GO:0006544 22 14 0,000 0,08165072 0,12595349 ! pituitary gland development GO:0021983 23 14 0,000 0,08165072 0,12586907 ! cellular response to starvation GO:0009267 21 14 0,000 0,08165072 0,12578477 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,08165072 0,12570057 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,08165072 0,12561649 ! regulation of heart rate GO:0002027 23 14 0,000 0,08165072 0,12553252 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,08165072 0,12544867 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,08165072 0,12536492 ! embryo implantation GO:0007566 27 14 0,000 0,08165072 0,12528129 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,08165072 0,12519777 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,08165072 0,12511436 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,08165072 0,12503106 ! axon cargo transport GO:0008088 27 14 0,000 0,08165072 0,12494787 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,08165072 0,1248648 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,08165072 0,12478183 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,08165072 0,12469897 ! mRNA splice site selection GO:0006376 26 14 0,000 0,08165072 0,12461623 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,08165072 0,12453359 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,08165072 0,12445106 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,08165072 0,12436865 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,08165072 0,12428634 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,08165072 0,12420414 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,08165072 0,12412205 ! muscle maintenance GO:0046716 19 14 0,000 0,08165072 0,12404006 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,08165072 0,12395819 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,08165072 0,12387642 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,08165072 0,12379476 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,08165072 0,12371321 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,08165072 0,12363177 ! cilium assembly GO:0042384 20 14 0,000 0,08165072 0,12355043 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,08488306 0,12835703 GO:0010498|proteasomal protein catabolic process, ! response to protein stimulus GO:0051789 111 81 1,000 0,08669954 0,1310177 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,08669954 0,13093167 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of cell size GO:0045793 20 15 0,000 0,08722348 0,13163649 ! metencephalon development GO:0022037 19 15 0,000 0,08722348 0,13155017 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,08722348 0,13146396 ! skin development GO:0043588 25 15 0,000 0,08722348 0,13137787 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,08722348 0,13129189 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,08722348 0,13120602 ! lipid phosphorylation GO:0046834 23 15 0,000 0,08722348 0,13112027 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,08722348 0,13103462 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,08722348 0,13094909 ! bile acid metabolic process GO:0008206 22 15 0,000 0,08722348 0,13086367 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,08722348 0,13077836 ! adult walking behavior GO:0007628 25 15 0,000 0,08722348 0,13069317 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,08722348 0,13060808 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,08722348 0,1305231 ! myoblast differentiation GO:0045445 27 15 0,000 0,08722348 0,13043824 ! centrosome cycle GO:0007098 16 15 0,000 0,08722348 0,13035348 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,08722348 0,13026884 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,08722348 0,1301843 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,08722348 0,13009988 ! cerebral cortex development GO:0021987 29 15 0,000 0,08722348 0,13001556 ! response to osmotic stress GO:0006970 22 15 0,000 0,08722348 0,12993135 ! vesicle coating GO:0006901 25 15 0,000 0,08722348 0,12984726 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,08722348 0,12976327 ! DNA integration GO:0015074 22 15 0,000 0,08722348 0,12967939 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,08722348 0,12959561 ! regulation of vasodilation GO:0042312 24 15 0,000 0,08722348 0,12951195 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,08722348 0,12942839 ! neuron recognition GO:0008038 22 15 0,000 0,08722348 0,12934494 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,08722348 0,1292616 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,08722348 0,12917837 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,08722348 0,12909524 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,08722348 0,12901222 ! biomineral formation GO:0031214 18 15 0,000 0,08722348 0,12892931 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,08722348 0,12884651 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,08722348 0,12876381 ! dopamine metabolic process GO:0042417 30 15 0,000 0,08722348 0,12868121 ! organic cation transport GO:0015695 19 15 0,000 0,08722348 0,12859872 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,08722348 0,12851634 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,08722348 0,12843406 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,08722348 0,12835189 ! peptide hormone processing GO:0016486 19 15 0,000 0,08722348 0,12826983 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,08722348 0,12818787 ! detection of stimulus GO:0051606 108 82 1,000 0,08852773 0,13002157 ! regulation of defense response GO:0031347 117 84 1,000 0,09221844 0,13535571 ! protein secretion GO:0009306 27 16 0,000 0,09276275 0,1360678 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,09276275 0,13598108 ! bone remodeling GO:0046849 24 16 0,000 0,09276275 0,13589447 ! endothelial cell migration GO:0043542 22 16 0,000 0,09276275 0,13580797 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,09276275 0,13572157 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,09276275 0,13563529 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09276275 0,13554912 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,09276275 0,13546306 ! glial cell development GO:0021782 24 16 0,000 0,09276275 0,1353771 ! patterning of blood vessels GO:0001569 24 16 0,000 0,09276275 0,13529126 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,09276275 0,13520552 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,09276275 0,1351199 ! protein polyubiquitination GO:0000209 26 16 0,000 0,09276275 0,13503438 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,09276275 0,13494897 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,09276275 0,13486366 ! fructose metabolic process GO:0006000 20 16 0,000 0,09276275 0,13477847 ! regulation of protein binding GO:0043393 27 16 0,000 0,09276275 0,13469338 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,09276275 0,1346084 ! protein export from nucleus GO:0006611 24 16 0,000 0,09276275 0,13452353 ! negative regulation of immune response GO:0050777 28 16 0,000 0,09276275 0,13443876 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,09276275 0,1343541 ! DNA replication initiation GO:0006270 25 16 0,000 0,09276275 0,13426955 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,09276275 0,1341851 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,09276275 0,13410076 ! diencephalon development GO:0021536 25 16 0,000 0,09276275 0,13401653 ! oogenesis GO:0048477 23 16 0,000 0,09276275 0,1339324 ! neural crest cell migration GO:0001755 24 16 0,000 0,09276275 0,13384838 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,09276275 0,13376446 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,09276275 0,13368065 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,09276275 0,13359694 ! steroid catabolic process GO:0006706 22 16 0,000 0,09276275 0,13351334 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,09276275 0,13342984 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,09276275 0,13334645 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,09276275 0,13326316 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,09276275 0,13317997 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,09276275 0,13309689 ! sperm-egg recognition GO:0035036 16 16 0,000 0,09276275 0,13301391 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,09276275 0,13293104 ! nerve development GO:0021675 18 16 0,000 0,09276275 0,13284827 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,09276275 0,1327656 ! rRNA metabolic process GO:0016072 107 85 1,000 0,09408054 0,13456794 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,09408054 0,13448431 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,09408054 0,13440078 ! regulation of membrane potential GO:0042391 128 85 1,000 0,09408054 0,13431735 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,09408054 0,13423403 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,09783727 0,13950758 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 1,000 0,09783727 0,13942115 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,09826871 0,13994924 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,09826871 0,13986264 ! negative regulation of defense response GO:0031348 19 17 0,000 0,09826871 0,13977615 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,09826871 0,13968976 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,09826871 0,13960348 ! glycerol metabolic process GO:0006071 20 17 0,000 0,09826871 0,1395173 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,09826871 0,13943123 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,09826871 0,13934527 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,09826871 0,13925941 ! signal complex assembly GO:0007172 29 17 0,000 0,09826871 0,13917366 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,09826871 0,13908802 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,09826871 0,13900248 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,09826871 0,13891704 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,09826871 0,13883171 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,09826871 0,13874649 ! memory GO:0007613 25 17 0,000 0,09826871 0,13866137 ! keratinization GO:0031424 17 17 0,000 0,09826871 0,13857635 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,09826871 0,13849144 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,09826871 0,13840663 ! retinoid metabolic process GO:0001523 22 17 0,000 0,09826871 0,13832193 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,09826871 0,13823733 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,09826871 0,13815283 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,09826871 0,13806844 ! vacuolar transport GO:0007034 24 17 0,000 0,09826871 0,13798415 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,09826871 0,13789996 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,09826871 0,13781587 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,09826871 0,13773189 ! membrane budding GO:0006900 29 17 0,000 0,09826871 0,13764801 ! heme metabolic process GO:0042168 27 17 0,000 0,09826871 0,13756423 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,09826871 0,13748055 ! body fluid secretion GO:0007589 27 17 0,000 0,09826871 0,13739698 ! stem cell differentiation GO:0048863 36 17 0,000 0,09826871 0,13731351 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,09826871 0,13723013 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,09826871 0,13714686 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,09826871 0,13706369 ! sensory perception of pain GO:0019233 23 17 0,000 0,09826871 0,13698062 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,09826871 0,13689766 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,09826871 0,13681479 ! synaptogenesis GO:0007416 24 17 0,000 0,09826871 0,13673202 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,09826871 0,13664935 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,09826871 0,13656679 ! cell-cell junction organization GO:0045216 25 17 0,000 0,09826871 0,13648432 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,09826871 0,13640195 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,09826871 0,13631968 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,09826871 0,13623751 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,09826871 0,13615544 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,09826871 0,13607347 ! protein processing GO:0016485 114 88 1,000 0,0997315 0,13801592 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,10163605 0,14056699 ! hormone metabolic process GO:0042445 121 90 1,000 0,10355072 0,143129 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,10374157 0,14330667 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,10374157 0,14322065 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,10374157 0,14313474 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,10374157 0,14304893 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,10374157 0,14296322 ! cAMP metabolic process GO:0046058 33 18 0,000 0,10374157 0,14287761 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,10374157 0,14279211 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,10374157 0,1427067 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,10374157 0,1426214 ! axis specification GO:0009798 26 18 0,000 0,10374157 0,14253621 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,10374157 0,14245111 GO:0050886|endocrine process, ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,10374157 0,14236612 ! glutamine metabolic process GO:0006541 23 18 0,000 0,10374157 0,14228122 ! response to retinoic acid GO:0032526 25 18 0,000 0,10374157 0,14219643 ! pigmentation during development GO:0048066 31 18 0,000 0,10374157 0,14211174 ! central nervous system neuron development GO:0021954 30 18 0,000 0,10374157 0,14202715 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,10374157 0,14194266 ! fucose metabolic process GO:0006004 26 18 0,000 0,10374157 0,14185827 ! response to fungus GO:0009620 19 18 0,000 0,10374157 0,14177398 ! peptide cross-linking GO:0018149 31 18 0,000 0,10374157 0,14168979 ! heart process GO:0003015 27 18 0,000 0,10374157 0,1416057 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,10374157 0,14152171 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,10374157 0,14143782 ! visual learning GO:0008542 35 18 0,000 0,10374157 0,14135403 ! somitogenesis GO:0001756 24 18 0,000 0,10374157 0,14127034 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,10374157 0,14118675 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,10374157 0,14110326 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,10374157 0,14101986 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,10374157 0,14093657 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,10374157 0,14085337 ! vitamin transport GO:0051180 24 18 0,000 0,10374157 0,14077027 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,10374157 0,14068727 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,10374157 0,14060437 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,10374157 0,14052156 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,10374157 0,14043885 ! cell-cell recognition GO:0009988 20 18 0,000 0,10374157 0,14035624 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,10374157 0,14027373 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,10374157 0,14019131 ! regulation of glucose import GO:0046324 21 18 0,000 0,10374157 0,14010899 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,10374157 0,14002677 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,10374157 0,13994464 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,10918153 0,14719666 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,10918153 0,14711043 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,10918153 0,1470243 ! positive regulation of ossification GO:0045778 30 19 0,000 0,10918153 0,14693827 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,10918153 0,14685234 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,10918153 0,14676652 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,10918153 0,14668079 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,10918153 0,14659516 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,10918153 0,14650963 ! regeneration GO:0031099 32 19 0,000 0,10918153 0,1464242 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,10918153 0,14633887 ! sensory perception of taste GO:0050909 23 19 0,000 0,10918153 0,14625365 ! smooth muscle contraction GO:0006939 36 19 0,000 0,10918153 0,14616852 ! peroxisome organization GO:0007031 29 19 0,000 0,10918153 0,14608348 ! digestive system process GO:0022600 30 19 0,000 0,10918153 0,14599855 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,10918153 0,14591372 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,10918153 0,14582898 ! response to vitamin A GO:0033189 26 19 0,000 0,10918153 0,14574435 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,10918153 0,14565981 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,10918153 0,14557537 ! response to starvation GO:0042594 30 19 0,000 0,10918153 0,14549102 ! sex determination GO:0007530 29 19 0,000 0,10918153 0,14540678 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,10918153 0,14532263 ! plasma membrane fusion GO:0045026 23 19 0,000 0,10918153 0,14523858 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,10918153 0,14515463 ! cytolysis GO:0019835 20 19 0,000 0,10918153 0,14507077 ! renal system process GO:0003014 35 19 0,000 0,10918153 0,14498701 ! vasodilation GO:0042311 33 19 0,000 0,10918153 0,14490335 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,10918153 0,14481979 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,10918153 0,14473632 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,10918153 0,14465294 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,10918153 0,14456967 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,10918153 0,14448648 ! sarcomere organization GO:0045214 23 19 0,000 0,10918153 0,1444034 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,10918153 0,14432041 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,10918153 0,14423751 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,10918153 0,14415471 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,10918153 0,14407201 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,10918153 0,1439894 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,10918153 0,14390688 ! protein stabilization GO:0050821 26 19 0,000 0,10918153 0,14382446 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,10935359 0,14396867 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,10935359 0,1438863 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,11458877 0,15068849 ! iron ion transport GO:0006826 37 20 0,000 0,11458877 0,15060239 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,11458877 0,15051638 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,11458877 0,15043047 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,11458877 0,15034465 ! response to vitamin GO:0033273 29 20 0,000 0,11458877 0,15025894 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,11458877 0,15017332 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,11458877 0,1500878 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,11458877 0,15000238 ! spinal cord development GO:0021510 31 20 0,000 0,11458877 0,14991705 ! response to ethanol GO:0045471 37 20 0,000 0,11458877 0,14983182 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,11458877 0,14974669 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,11458877 0,14966166 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,11458877 0,14957672 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,11458877 0,14949188 ! chromosome condensation GO:0030261 31 20 0,000 0,11458877 0,14940713 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,11458877 0,14932248 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,11458877 0,14923793 ! pallium development GO:0021543 38 20 0,000 0,11458877 0,14915347 ! DNA modification GO:0006304 28 20 0,000 0,11458877 0,1490691 ! collagen fibril organization GO:0030199 45 20 0,000 0,11458877 0,14898484 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,11458877 0,14890067 ! collagen catabolic process GO:0030574 25 20 0,000 0,11458877 0,14881659 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,11458877 0,14873261 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,11458877 0,14864872 ! alditol metabolic process GO:0019400 24 20 0,000 0,11458877 0,14856493 ! actin filament-based movement GO:0030048 34 20 0,000 0,11458877 0,14848123 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,11524087 0,14924211 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,11524087 0,14915813 ! protein maturation GO:0051604 129 96 1,000 0,11524087 0,14907424 ! response to light stimulus GO:0009416 153 96 1,000 0,11524087 0,14899044 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,11996351 0,15500902 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,11996351 0,15492199 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,11996351 0,15483505 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,11996351 0,15474821 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,11996351 0,15466147 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,11996351 0,15457483 GO:0009799|determination of symmetry, ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,11996351 0,15448828 GO:0034105|positive regulation of tissue remodeling, ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,11996351 0,15440183 ! protein amino acid acylation GO:0043543 37 21 0,000 0,11996351 0,15431547 ! vesicle docking GO:0048278 27 21 0,000 0,11996351 0,15422921 ! phototransduction GO:0007602 25 21 0,000 0,11996351 0,15414305 ! dendrite development GO:0016358 35 21 0,000 0,11996351 0,15405699 ! visual behavior GO:0007632 39 21 0,000 0,11996351 0,15397102 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,11996351 0,15388514 ! ovarian follicle development GO:0001541 30 21 0,000 0,11996351 0,15379937 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,11996351 0,15371368 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,11996351 0,1536281 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,11996351 0,15354261 ! cell aging GO:0007569 32 21 0,000 0,11996351 0,15345721 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,11996351 0,15337191 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,11996351 0,1532867 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,11996351 0,15320159 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,11996351 0,15311657 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,11996351 0,15303165 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,11996351 0,15294682 ! fatty acid transport GO:0015908 30 21 0,000 0,11996351 0,15286209 ! immunoglobulin production GO:0002377 33 21 0,000 0,11996351 0,15277744 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,11996351 0,1526929 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,11996351 0,15260844 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,11996351 0,15252408 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,11996351 0,15243981 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,11996351 0,15235564 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,11996351 0,15227156 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,11996351 0,15218757 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,11996351 0,15210367 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,11996351 0,15201987 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,11996351 0,15193616 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,11996351 0,15185254 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,11996351 0,15176901 ! extracellular structure organization GO:0043062 156 99 1,000 0,12120767 0,15325874 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,12530592 0,15835363 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,12530592 0,15826667 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,12530592 0,15817981 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,12530592 0,15809304 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,12530592 0,15800637 ! leukocyte adhesion GO:0007159 38 22 0,000 0,12530592 0,15791979 ! molting cycle process GO:0022404 40 22 0,000 0,12530592 0,1578333 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,12530592 0,15774691 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,12530592 0,15766062 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,12530592 0,15757442 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,12530592 0,15748831 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,12530592 0,1574023 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,12530592 0,15731638 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,12530592 0,15723056 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,12530592 0,15714483 ! lysosome organization GO:0007040 37 22 0,000 0,12530592 0,15705919 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,12530592 0,15697365 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,12530592 0,15688819 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,12530592 0,15680284 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,12530592 0,15671757 ! membrane depolarization GO:0051899 35 22 0,000 0,12530592 0,1566324 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,12530592 0,15654732 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,12530592 0,15646233 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,12530592 0,15637744 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,12530592 0,15629263 ! neural tube closure GO:0001843 33 22 0,000 0,12530592 0,15620792 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,12530592 0,1561233 ! protein tetramerization GO:0051262 39 22 0,000 0,12530592 0,15603877 ! neuron fate commitment GO:0048663 32 23 0,000 0,1306162 0,16256346 ! embryonic pattern specification GO:0009880 31 23 0,000 0,1306162 0,16247554 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,1306162 0,16238771 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,1306162 0,16229998 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,1306162 0,16221235 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,1306162 0,16212481 ! vesicle targeting GO:0006903 32 23 0,000 0,1306162 0,16203736 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,1306162 0,16195001 ! osteoblast differentiation GO:0001649 40 23 0,000 0,1306162 0,16186275 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,1306162 0,16177559 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,1306162 0,16168852 ! interaction with host GO:0051701 37 23 0,000 0,1306162 0,16160154 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,1306162 0,16151466 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,1306162 0,16142787 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,1306162 0,16134118 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,1306162 0,16125457 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,1306162 0,16116806 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,1306162 0,16108165 ! cell fate determination GO:0001709 45 23 0,000 0,1306162 0,16099532 ! pentose metabolic process GO:0019321 31 23 0,000 0,1306162 0,16090909 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,1306162 0,16082295 ! spermatid development GO:0007286 33 23 0,000 0,1306162 0,1607369 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,1306162 0,16065095 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,1306162 0,16056508 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,1306162 0,16047931 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,1306162 0,16039363 ! telomere organization GO:0032200 32 23 0,000 0,1306162 0,16030804 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,1306162 0,16022254 ! regulation of amine transport GO:0051952 38 23 0,000 0,1306162 0,16013714 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,13589455 0,1665197 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,13589455 0,16643103 ! initiation of viral infection GO:0019059 42 24 0,000 0,13589455 0,16634245 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,13589455 0,16625397 ! superoxide metabolic process GO:0006801 32 24 0,000 0,13589455 0,16616559 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,13589455 0,16607729 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,13589455 0,1659891 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,13589455 0,16590099 ! sperm motility GO:0030317 27 24 0,000 0,13589455 0,16581298 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,13589455 0,16572506 ! vacuole organization GO:0007033 39 24 0,000 0,13589455 0,16563724 ! receptor metabolic process GO:0043112 37 24 0,000 0,13589455 0,16554951 ! neural crest cell development GO:0014032 39 24 0,000 0,13589455 0,16546187 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,13589455 0,16537432 ! negative regulation of cell development GO:0010721 56 24 0,000 0,13589455 0,16528687 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 0,000 0,13589455 0,16519951 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,13589455 0,16511224 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,13589455 0,16502506 ! glutathione metabolic process GO:0006749 29 24 0,000 0,13589455 0,16493798 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,13589455 0,16485099 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,14114115 0,17112528 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,14114115 0,17103512 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,14114115 0,17094505 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,14114115 0,17085508 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,14114115 0,1707652 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,14114115 0,17067542 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,14114115 0,17058573 ! male gonad development GO:0008584 33 25 0,000 0,14114115 0,17049614 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,14114115 0,17040664 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,14114115 0,17031724 ! phospholipid transport GO:0015914 35 25 0,000 0,14114115 0,17022793 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,14114115 0,17013871 ! detection of light stimulus GO:0009583 30 25 0,000 0,14114115 0,17004958 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,14114115 0,16996055 ! leukocyte proliferation GO:0070661 39 25 0,000 0,14114115 0,16987161 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,1463562 0,1760561 ! translational initiation GO:0006413 43 26 0,000 0,1463562 0,17596407 ! regulation of pH GO:0006885 36 26 0,000 0,1463562 0,17587213 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,1463562 0,17578029 ! circadian rhythm GO:0007623 42 26 0,000 0,1463562 0,17568855 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,1463562 0,1755969 ! post-embryonic development GO:0009791 42 26 0,000 0,1463562 0,17550535 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,1463562 0,17541389 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,1463562 0,17532253 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,1463562 0,17523126 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,1463562 0,17514009 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,1463562 0,17504902 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,1463562 0,17495803 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,1463562 0,17486715 ! regulation of coagulation GO:0050818 39 26 0,000 0,1463562 0,17477635 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,15153987 0,18087271 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,15153987 0,1807789 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,15153987 0,18068518 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,15153987 0,18059156 ! membrane docking GO:0022406 39 27 0,000 0,15153987 0,18049804 ! catechol metabolic process GO:0009712 43 27 0,000 0,15153987 0,18040461 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,15153987 0,18031128 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,15153987 0,18021805 ! myofibril assembly GO:0030239 36 27 0,000 0,15153987 0,18012492 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,15153987 0,18003188 ! response to ionizing radiation GO:0010212 47 27 0,000 0,15153987 0,17993893 ! natural killer cell activation GO:0030101 35 27 0,000 0,15153987 0,17984608 ! lipid oxidation GO:0034440 38 27 0,000 0,15153987 0,17975333 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,15153987 0,17966068 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,15153987 0,17956811 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,15153987 0,17947565 ! gene silencing GO:0016458 41 27 0,000 0,15153987 0,17938328 ! phenol metabolic process GO:0018958 44 28 0,000 0,15669237 0,18538706 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,15669237 0,18529175 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,15669237 0,18519653 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,15669237 0,18510141 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,15669237 0,18500639 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,15669237 0,18491147 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,15669237 0,18481664 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,15669237 0,18472191 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,15669237 0,18462728 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,15669237 0,18453274 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,15669237 0,1844383 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,15669237 0,18434396 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,15669237 0,18424972 ! mesoderm formation GO:0001707 46 28 0,000 0,15669237 0,18415557 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,15669237 0,18406151 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,15669237 0,18396756 ! BMP signaling pathway GO:0030509 40 28 0,000 0,15669237 0,1838737 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,15669237 0,18377993 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,15669237 0,18368626 ! neural tube formation GO:0001841 41 28 0,000 0,15669237 0,18359269 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,15669237 0,18349921 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,16181386 0,18940045 ! regulation of innate immune response GO:0045088 38 29 0,000 0,16181386 0,18930411 ! ovulation cycle process GO:0022602 41 29 0,000 0,16181386 0,18920787 ! protein targeting to membrane GO:0006612 53 29 0,000 0,16181386 0,18911173 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,16181386 0,18901569 ! mismatch repair GO:0006298 34 29 0,000 0,16181386 0,18891974 ! muscle cell development GO:0055001 38 29 0,000 0,16181386 0,18882389 ! formation of primary germ layer GO:0001704 48 29 0,000 0,16181386 0,18872814 ! telencephalon development GO:0021537 52 29 0,000 0,16181386 0,18863248 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,16181386 0,18853692 ! tissue homeostasis GO:0001894 42 29 0,000 0,16181386 0,18844146 GO:0048871|multicellular organismal homeostasis, ! collagen metabolic process GO:0032963 40 30 0,000 0,16690455 0,19427149 ! organic anion transport GO:0015711 51 30 0,000 0,16690455 0,19417322 ! cholesterol transport GO:0030301 46 30 0,000 0,16690455 0,19407506 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,16690455 0,19397699 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,16690455 0,19387902 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,16690455 0,19378115 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,16690455 0,19368338 ! ceramide metabolic process GO:0006672 43 30 0,000 0,16690455 0,19358571 ! ovulation cycle GO:0042698 43 30 0,000 0,16690455 0,19348814 ! hindbrain development GO:0030902 45 30 0,000 0,16690455 0,19339066 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,16690455 0,19329329 ! adult locomotory behavior GO:0008344 47 30 0,000 0,16690455 0,19319601 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,16690455 0,19309883 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,16690455 0,19300174 ! response to heat GO:0009408 41 30 0,000 0,16690455 0,19290476 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,16690455 0,19280787 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,16690455 0,19271108 ! glial cell differentiation GO:0010001 55 31 0,000 0,17196461 0,19845389 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,17196461 0,19835436 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,17196461 0,19825494 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,17196461 0,19815561 ! odontogenesis GO:0042476 50 31 0,000 0,17196461 0,19805638 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,17196461 0,19795726 ! segmentation GO:0035282 41 31 0,000 0,17196461 0,19785823 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,17196461 0,1977593 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,17196461 0,19766047 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,17196461 0,19756174 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,17196461 0,1974631 ! RNA modification GO:0009451 40 31 0,000 0,17196461 0,19736457 ! regulation of muscle development GO:0048634 48 32 0,000 0,17699422 0,20303576 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,17699422 0,20293455 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,17699422 0,20283343 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,17699422 0,20273242 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,17699422 0,20263151 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,17699422 0,2025307 ! cytokine production GO:0001816 44 32 0,000 0,17699422 0,20242999 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,17699422 0,20232938 ! vesicle localization GO:0051648 47 32 0,000 0,17699422 0,20222886 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,18199357 0,20783774 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,18199357 0,20773459 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,18199357 0,20763155 ! actomyosin structure organization GO:0031032 43 33 0,000 0,18199357 0,20752861 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,18199357 0,20742577 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,18199357 0,20732303 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,18199357 0,2072204 ! female gonad development GO:0008585 49 33 0,000 0,18199357 0,20711786 ! positive regulation of cell development GO:0010720 54 33 0,000 0,18199357 0,20701543 ! lipid homeostasis GO:0055088 55 33 0,000 0,18199357 0,2069131 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,18199357 0,20681087 ! regulation of proteolysis GO:0030162 50 33 0,000 0,18199357 0,20670874 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,18199357 0,20660671 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,18199357 0,20650479 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,18199357 0,20640296 ! mRNA catabolic process GO:0006402 48 34 0,000 0,18696283 0,21193421 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,18696283 0,21182981 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,18696283 0,21172551 ! feeding behavior GO:0007631 45 34 0,000 0,18696283 0,21162131 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,18696283 0,21151722 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,18696283 0,21141323 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,18696283 0,21130934 ! neuron migration GO:0001764 46 34 0,000 0,18696283 0,21120555 ! female gamete generation GO:0007292 43 34 0,000 0,18696283 0,21110187 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,18696283 0,21099829 ! polyol metabolic process GO:0019751 44 34 0,000 0,18696283 0,21089481 ! aerobic respiration GO:0009060 47 34 0,000 0,18696283 0,21079143 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,18696283 0,21068815 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,18696283 0,21058497 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,19190219 0,2160426 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,19190219 0,21593691 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,19190219 0,21583131 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,19190219 0,21572582 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,19190219 0,21562044 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,19190219 0,21551515 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,19190219 0,21540997 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,19190219 0,2153049 ! glycogen metabolic process GO:0005977 48 35 0,000 0,19190219 0,21519992 ! pigment metabolic process GO:0042440 61 35 0,000 0,19190219 0,21509505 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,19681182 0,22049059 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,19681182 0,22038325 ! organic ether metabolic process GO:0018904 46 36 0,000 0,19681182 0,22027601 ! tissue remodeling GO:0048771 62 36 0,000 0,19681182 0,22016887 ! neural tube development GO:0021915 50 36 0,000 0,19681182 0,22006183 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,19681182 0,2199549 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,19681182 0,21984808 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,19681182 0,21974135 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,19681182 0,21963474 ! glucan metabolic process GO:0044042 49 36 0,000 0,19681182 0,21952822 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,20169191 0,22486252 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,20169191 0,22475358 ! learning GO:0007612 67 37 0,000 0,20169191 0,22464474 ! ion transmembrane transport GO:0034220 56 37 0,000 0,20169191 0,224536 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,20169191 0,22442738 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,20169191 0,22431885 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,20654262 0,22960272 ! gliogenesis GO:0042063 71 38 0,000 0,20654262 0,2294918 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,20654262 0,22938099 ! mesenchymal cell development GO:0014031 64 38 0,000 0,20654262 0,22927028 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,20654262 0,22915968 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,21136413 0,2343961 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,21136413 0,23428313 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,21136413 0,23417028 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,21136413 0,23405754 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,21136413 0,2339449 ! male sex differentiation GO:0046661 53 39 0,000 0,21136413 0,23383237 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,21136413 0,23371995 ! chromatin remodeling GO:0006338 68 39 0,000 0,21136413 0,23360764 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,21136413 0,23349544 ! JNK cascade GO:0007254 54 39 0,000 0,21136413 0,23338334 ! developmental growth GO:0048589 62 39 0,000 0,21136413 0,23327135 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,21615662 0,23844615 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,21615662 0,23833184 ! regulation of tube size GO:0035150 60 40 0,000 0,21615662 0,23821765 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,21615662 0,23810356 ! peptide metabolic process GO:0006518 56 40 0,000 0,21615662 0,23798958 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,21615662 0,23787571 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,21615662 0,23776195 ! B cell differentiation GO:0030183 62 40 0,000 0,21615662 0,23764829 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,21615662 0,23753475 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,22092026 0,24265358 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,22092026 0,24253776 ! endosome transport GO:0016197 71 41 0,000 0,22092026 0,24242204 ! striated muscle contraction GO:0006941 62 41 0,000 0,22092026 0,24230644 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,22092026 0,24219094 ! biopolymer methylation GO:0043414 62 41 0,000 0,22092026 0,24207556 ! mitochondrial transport GO:0006839 60 42 0,000 0,22565522 0,24714619 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,22565522 0,24702856 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,22565522 0,24691104 ! excretion GO:0007588 63 42 0,000 0,22565522 0,24679363 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,22565522 0,24667634 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,22565522 0,24655915 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,22565522 0,24644207 ! regulation of cell shape GO:0008360 78 42 0,000 0,22565522 0,24632511 ! neuromuscular process GO:0050905 79 43 0,000 0,23036167 0,25134338 ! vesicle organization GO:0016050 79 43 0,000 0,23036167 0,25122421 ! methylation GO:0032259 64 43 0,000 0,23036167 0,25110514 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,23503979 0,25608314 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,23503979 0,25596189 ! glycolysis GO:0006096 53 44 0,000 0,23503979 0,25584076 ! regulation of ion transport GO:0043269 57 44 0,000 0,23503979 0,25571973 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,23503979 0,25559883 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,23503979 0,25547803 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,23503979 0,25535735 ! RNA catabolic process GO:0006401 64 45 0,000 0,23968974 0,26028631 ! regulation of translational initiation GO:0006446 64 45 0,000 0,23968974 0,26016347 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,23968974 0,26004075 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,23968974 0,25991815 ! cell recognition GO:0008037 58 45 0,000 0,23968974 0,25979566 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,24431168 0,26468058 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,24431168 0,26455597 ! cell redox homeostasis GO:0045454 63 46 0,000 0,24431168 0,26443147 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,24431168 0,26430709 ! histone modification GO:0016570 68 46 0,000 0,24431168 0,26418283 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,2489058 0,26902412 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,2489058 0,26889776 ! covalent chromatin modification GO:0016569 75 47 0,000 0,2489058 0,26877152 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,2489058 0,26864539 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,2489058 0,26851939 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,2489058 0,2683935 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,2489058 0,26826773 ! chloride transport GO:0006821 67 48 0,000 0,25347224 0,27306143 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,25347224 0,2729336 ! response to temperature stimulus GO:0009266 62 48 0,000 0,25347224 0,27280588 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,25347224 0,27267828 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,25347224 0,2725508 ! gastrulation GO:0007369 73 48 0,000 0,25347224 0,27242344 ! heart morphogenesis GO:0003007 65 48 0,000 0,25347224 0,2722962 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,25347224 0,27216908 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,25347224 0,27204207 ! regulation of endocytosis GO:0030100 63 48 0,000 0,25347224 0,27191519 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,25801119 0,27665535 ! sensory perception of smell GO:0007608 61 49 0,000 0,25801119 0,27652644 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,25801119 0,27639764 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,25801119 0,27626896 ! germ cell development GO:0007281 68 49 0,000 0,25801119 0,27614041 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,25801119 0,27601197 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,25801119 0,27588365 ! maintenance of location GO:0051235 84 49 0,000 0,25801119 0,27575545 ! regulation of actin filament length GO:0030832 72 50 0,000 0,26252279 0,28044702 ! membrane fusion GO:0006944 80 50 0,000 0,26252279 0,28031682 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,26252279 0,28018674 ! lipid modification GO:0030258 73 50 0,000 0,26252279 0,28005678 ! positive regulation of growth GO:0045927 67 50 0,000 0,26252279 0,27992695 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,26252279 0,27979723 ! proton transport GO:0015992 75 50 0,000 0,26252279 0,27966763 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,26252279 0,27953816 ! hydrogen transport GO:0006818 77 51 0,000 0,26700722 0,28418168 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,26700722 0,28405024 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,26700722 0,28391891 ! adult behavior GO:0030534 80 51 0,000 0,26700722 0,28378771 ! transition metal ion transport GO:0000041 74 52 0,000 0,27146464 0,288392 ! regulation of cellular component size GO:0032535 74 52 0,000 0,27146464 0,28825885 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,27146464 0,28812583 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,27146464 0,28799293 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,2758952 0,29255831 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,2758952 0,29242349 ! single fertilization GO:0007338 59 53 0,000 0,2758952 0,29228879 ! cell projection assembly GO:0030031 76 53 0,000 0,2758952 0,29215422 ! amino acid transport GO:0006865 84 54 0,000 0,28029908 0,29668103 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,28029908 0,29654456 ! glucose catabolic process GO:0006007 66 54 0,000 0,28029908 0,29640822 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,28029908 0,296272 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,28029908 0,29613591 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,28029908 0,29599994 ! exocytosis GO:0006887 74 55 0,000 0,28467642 0,30048452 ! mesoderm development GO:0007498 76 55 0,000 0,28467642 0,30034668 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,28467642 0,30020897 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,28467642 0,30007139 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,28902739 0,30451809 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,29335214 0,30893311 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,29335214 0,30879172 ! gonad development GO:0008406 79 57 0,000 0,29335214 0,30865046 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,29765083 0,31303013 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,30192361 0,31737857 ! activation of MAPK activity GO:0000187 84 59 0,000 0,30192361 0,31723358 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,30192361 0,31708872 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,30617065 0,32140232 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,30617065 0,3212557 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,30617065 0,32110921 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,30617065 0,32096285 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,30617065 0,32081662 ! regulation of heart contraction GO:0008016 91 60 0,000 0,30617065 0,32067053 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,30617065 0,32052457 ! fertilization GO:0009566 68 60 0,000 0,30617065 0,32037875 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,31039209 0,32464838 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,31039209 0,32450082 ! extracellular matrix organization GO:0030198 103 61 0,000 0,31039209 0,32435338 ! amine catabolic process GO:0009310 90 62 0,000 0,31458808 0,32858882 ! neurotransmitter transport GO:0006836 81 62 0,000 0,31458808 0,32843967 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,31458808 0,32829065 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,31875879 0,33249216 ! regulation of lipase activity GO:0060191 109 63 0,000 0,31875879 0,33234144 ! appendage morphogenesis GO:0035107 93 64 0,000 0,32290435 0,3365111 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,32290435 0,3363587 ! hexose catabolic process GO:0019320 82 64 0,000 0,32290435 0,33620643 ! adaptive immune response GO:0002250 94 64 0,000 0,32290435 0,3360543 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 0,000 0,32702492 0,34018875 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,32702492 0,34003495 ! activation of immune response GO:0002253 83 65 0,000 0,32702492 0,3398813 ! antigen processing and presentation GO:0019882 96 66 0,000 0,33112065 0,34398261 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,33519169 0,34805458 ! learning or memory GO:0007611 123 68 0,000 0,33923819 0,35209739 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,33923819 0,35193858 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,33923819 0,3517799 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,33923819 0,35162137 ! rhythmic process GO:0048511 105 68 0,000 0,33923819 0,35146299 ! inorganic anion transport GO:0015698 93 68 0,000 0,33923819 0,35130474 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,34326028 0,35530992 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,34326028 0,35515009 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,34725812 0,35912486 ! amine transport GO:0015837 101 70 0,000 0,34725812 0,35896345 ! regulation of catabolic process GO:0009894 106 70 0,000 0,34725812 0,35880219 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,35123185 0,36274507 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,35123185 0,36258226 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,35123185 0,36241959 ! response to hypoxia GO:0001666 132 72 0,000 0,35518162 0,36633082 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,35518162 0,36616662 ! regulation of blood pressure GO:0008217 107 73 0,000 0,35910757 0,37004812 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,35910757 0,36988241 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,36300984 0,37373439 ! response to oxygen levels GO:0070482 137 74 0,000 0,36300984 0,37356717 ! digestion GO:0007586 97 74 0,000 0,36300984 0,3734001 ! protein import into nucleus GO:0006606 118 74 0,000 0,36300984 0,37323318 ! response to nutrient GO:0007584 104 75 0,000 0,36688857 0,3770526 ! nuclear import GO:0051170 121 75 0,000 0,36688857 0,3768842 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,36688857 0,37671594 ! amine biosynthetic process GO:0009309 97 76 0,000 0,37074391 0,38050468 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,37074391 0,38033496 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,37457598 0,38409486 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,37457598 0,38392369 ! protein ubiquitination GO:0016567 125 77 0,000 0,37457598 0,38375268 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,37457598 0,38358182 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,37457598 0,38341111 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,37838494 0,38713762 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,37838494 0,38696548 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,38217092 0,39066361 ! cellular respiration GO:0045333 107 79 0,000 0,38217092 0,39049006 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,38217092 0,39031666 ! T cell activation GO:0042110 134 79 0,000 0,38217092 0,39014342 ! regulation of lyase activity GO:0051339 133 79 0,000 0,38217092 0,38997033 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,38217092 0,38979739 ! chromatin assembly GO:0031497 102 80 0,000 0,38593406 0,39346114 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,38593406 0,39328681 ! protein localization in nucleus GO:0034504 133 80 0,000 0,38593406 0,39311264 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,38967449 0,39674694 ! regulation of neurological system process GO:0031644 122 81 0,000 0,38967449 0,39657139 ! vitamin metabolic process GO:0006766 103 81 0,000 0,38967449 0,39639599 ! ossification GO:0001503 134 82 0,000 0,39339235 0,40000107 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,39708778 0,40358016 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,39708778 0,4034019 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,4007609 0,40695368 ! sterol metabolic process GO:0016125 120 84 0,000 0,4007609 0,40677409 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,40441186 0,41029876 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,40804078 0,41379797 ! nucleosome organization GO:0034728 114 87 0,000 0,4116478 0,4172719 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,4116478 0,41708808 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,4116478 0,41690442 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,4116478 0,41672092 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,41523304 0,42016542 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,41523304 0,41998065 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,41523304 0,41979604 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,41879665 0,42321278 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,41879665 0,42302692 ! leukocyte differentiation GO:0002521 143 90 0,000 0,42233874 0,42641751 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,42233874 0,4262304 ! ATP metabolic process GO:0046034 137 91 0,000 0,42585944 0,42959505 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,42935889 0,43293531 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,42935889 0,43274559 ! positive regulation of immune response GO:0050778 121 92 0,000 0,42935889 0,43255604 ! sulfur metabolic process GO:0006790 118 92 0,000 0,42935889 0,43236666 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,43283721 0,43567859 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,43283721 0,435488 ! electron transport chain GO:0022900 123 94 0,000 0,43629452 0,43877455 ! response to oxidative stress GO:0006979 141 94 0,000 0,43629452 0,43858278 ! angiogenesis GO:0001525 149 95 0,000 0,43973096 0,44184413 ! carboxylic acid transport GO:0046942 147 95 0,000 0,43973096 0,44165118 GO:0015849|organic acid transport, ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,44314664 0,44488751 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,4465417 0,44810031 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,45327042 0,45465415 ! protein import GO:0017038 156 99 0,000 0,45327042 0,45445596 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,45660433 0,45759911 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,45660433 0,45739981 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,45660433 0,45720068 ! divalent metal ion transport GO:0070838 171 100 0,000 0,45660433 0,45700172 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,45660433 0,45680294 ! protein localization in organelle GO:0033365 161 100 0,000 0,45660433 0,45660433