pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6853-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 3,000 9,489E-09 2,283E-05 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 6,000 1,198E-08 1,441E-05 ! positive regulation of phosphorylation GO:0042327 129 79 6,000 3,833E-08 3,074E-05 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 6,000 4,566E-08 2,747E-05 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of mast cell proliferation GO:0070666 81 48 5,000 4,593E-08 2,21E-05 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 3,000 5,639E-08 2,261E-05 ! regulation of leukocyte proliferation GO:0070663 88 51 5,000 6,673E-08 2,294E-05 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of T cell activation GO:0050863 158 94 6,000 1,286E-07 3,868E-05 ! positive regulation of leukocyte proliferation GO:0070665 62 38 4,000 4,911E-07 1,313E-04 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 5,000 5,395E-07 1,298E-04 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 6,25E-07 1,367E-04 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 4,000 6,396E-07 1,282E-04 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 2,000 6,771E-07 1,253E-04 GO:0022011|myelination in the peripheral nervous system, ! regulation of T cell proliferation GO:0042129 71 41 4,000 7,26E-07 1,248E-04 ! regulation of T cell differentiation GO:0045580 70 41 4,000 7,26E-07 1,165E-04 ! positive regulation of lymphocyte activation GO:0051251 127 77 5,000 8,051E-07 1,211E-04 ! positive regulation of translation GO:0045727 30 19 3,000 1,011E-06 1,431E-04 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 4,000 1,042E-06 1,392E-04 ! regulation of JAK-STAT cascade GO:0046425 70 45 4,000 1,168E-06 1,479E-04 ! male meiosis GO:0007140 7 6 2,000 1,35E-06 1,624E-04 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 2,000 1,35E-06 1,547E-04 GO:0033135|regulation of peptidyl-serine phosphorylation, ! Schwann cell development GO:0014044 15 6 2,000 1,35E-06 1,477E-04 ! positive regulation of cell activation GO:0050867 145 85 5,000 1,446E-06 1,513E-04 GO:0002696|positive regulation of leukocyte activation, ! regulation of adaptive immune response GO:0002819 84 47 4,000 1,457E-06 1,461E-04 ! regulation of lymphocyte differentiation GO:0045619 81 48 4,000 1,621E-06 1,56E-04 ! positive regulation of protein modification process GO:0031401 136 88 5,000 1,774E-06 1,641E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 1,891E-06 1,685E-04 ! positive regulation of B cell activation GO:0050871 38 22 3,000 1,891E-06 1,625E-04 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 4,000 2,202E-06 1,827E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 2,453E-06 1,968E-04 ! myelination GO:0042552 45 25 3,000 3,238E-06 2,513E-04 ! Schwann cell differentiation GO:0014037 19 8 2,000 3,758E-06 2,825E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 3,758E-06 2,74E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 3,758E-06 2,659E-04 ! myeloid cell homeostasis GO:0002262 13 8 2,000 3,758E-06 2,583E-04 ! positive regulation of MAPKKK cascade GO:0043410 47 26 3,000 3,815E-06 2,55E-04 ! ensheathment of neurons GO:0007272 57 30 3,000 6,905E-06 4,49E-04 GO:0008366|axon ensheathment, ! regulation of B cell activation GO:0050864 50 30 3,000 6,905E-06 4,372E-04 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 3,000 7,902E-06 4,875E-04 ! positive regulation of T cell proliferation GO:0042102 52 31 3,000 7,902E-06 4,753E-04 ! positive regulation of B cell proliferation GO:0030890 16 10 2,000 8,004E-06 4,697E-04 ! regulation of chemokine biosynthetic process GO:0045073 12 10 2,000 8,004E-06 4,585E-04 ! positive regulation of interleukin-6 production GO:0032755 14 10 2,000 8,004E-06 4,479E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 8,59E-06 4,697E-04 ! positive regulation of T cell activation GO:0050870 109 67 4,000 8,59E-06 4,593E-04 ! peripheral nervous system development GO:0007422 64 32 3,000 9,002E-06 4,709E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 9,241E-06 4,731E-04 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 2,000 1,097E-05 5,5E-04 ! regulation of MAPKKK cascade GO:0043408 142 71 4,000 1,143E-05 5,612E-04 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 3,000 1,154E-05 5,551E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 1,224E-05 5,775E-04 ! negative regulation of secretion GO:0051048 63 35 3,000 1,298E-05 6,007E-04 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 3,000 1,456E-05 6,61E-04 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 2,000 1,459E-05 6,499E-04 ! regulation of B cell proliferation GO:0030888 20 12 2,000 1,459E-05 6,381E-04 ! regulation of chemokine production GO:0032642 18 13 2,000 1,89E-05 8,122E-04 ! negative regulation of lipid metabolic process GO:0045833 19 13 2,000 1,89E-05 7,98E-04 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 2,000 1,89E-05 7,842E-04 ! Golgi organization GO:0007030 24 13 2,000 1,89E-05 7,709E-04 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 2,000 1,89E-05 7,581E-04 ! regulation of action potential in neuron GO:0019228 73 39 3,000 2,014E-05 7,943E-04 ! regulation of hormone secretion GO:0046883 62 40 3,000 2,23E-05 8,655E-04 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 2,000 2,399E-05 9,161E-04 ! negative regulation of transport GO:0051051 153 84 4,000 2,597E-05 9,762E-04 ! positive regulation of transcription factor activity GO:0051091 62 42 3,000 2,714E-05 1,005E-03 GO:0090047|positive regulation of transcription regulator activity, ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 2,983E-05 1,088E-03 ! regulation of T-helper cell differentiation GO:0045622 26 15 2,000 2,989E-05 1,074E-03 ! regulation of DNA binding GO:0051101 155 88 4,000 3,252E-05 1,151E-03 ! gland development GO:0048732 206 88 4,000 3,252E-05 1,134E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 3,579E-05 1,23E-03 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 2,000 3,668E-05 1,243E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 2,000 3,668E-05 1,226E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,907E-05 1,288E-03 ! positive regulation of DNA binding GO:0043388 73 47 3,000 4,257E-05 1,384E-03 ! glial cell development GO:0021782 27 17 2,000 4,441E-05 1,425E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 4,441E-05 1,406E-03 ! regulation of action potential GO:0001508 95 49 3,000 5,025E-05 1,57E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 2,000 5,313E-05 1,639E-03 ! regulation of immunoglobulin production GO:0002637 43 18 2,000 5,313E-05 1,618E-03 ! positive regulation of cytokine production GO:0001819 86 50 3,000 5,445E-05 1,637E-03 ! positive regulation of binding GO:0051099 78 51 3,000 5,889E-05 1,749E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 6,36E-05 1,866E-03 ! response to UV GO:0009411 104 53 3,000 6,857E-05 1,988E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 7,378E-05 2,113E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 7,378E-05 2,088E-03 ! regulation of interleukin-2 production GO:0032663 35 20 2,000 7,378E-05 2,064E-03 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 2,000 8,582E-05 2,373E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 2,000 8,582E-05 2,346E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 2,000 8,582E-05 2,32E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 9,133E-05 2,442E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 9,133E-05 2,415E-03 ! cytokine-mediated signaling pathway GO:0019221 97 59 3,000 1,046E-04 2,735E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 1,117E-04 2,889E-03 ! viral genome replication GO:0019079 41 23 2,000 1,136E-04 2,907E-03 ! regulation of interleukin-6 production GO:0032675 29 23 2,000 1,136E-04 2,877E-03 ! response to molecule of bacterial origin GO:0002237 34 23 2,000 1,136E-04 2,847E-03 ! regulation of alpha-beta T cell activation GO:0046634 42 24 2,000 1,294E-04 3,21E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 1,294E-04 3,178E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 1,294E-04 3,145E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,437E-04 3,457E-03 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 2,000 1,466E-04 3,493E-03 ! regulation of cytokine biosynthetic process GO:0042035 95 65 3,000 1,526E-04 3,6E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 1,653E-04 3,86E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,653E-04 3,823E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 1,653E-04 3,787E-03 GO:0045936|negative regulation of phosphate metabolic process, ! response to superoxide GO:0000303 10 5 1,000 1,668E-04 3,786E-03 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 1,000 1,668E-04 3,751E-03 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 1,668E-04 3,716E-03 ! response to protozoan GO:0001562 10 5 1,000 1,668E-04 3,682E-03 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 1,000 1,668E-04 3,648E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 1,668E-04 3,615E-03 ! microvillus organization GO:0032528 7 5 1,000 1,668E-04 3,583E-03 GO:0030033|microvillus assembly, ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 1,000 1,668E-04 3,552E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 1,668E-04 3,52E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,668E-04 3,49E-03 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 1,000 1,668E-04 3,46E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,668E-04 3,43E-03 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 1,668E-04 3,401E-03 ! organ regeneration GO:0031100 7 5 1,000 1,668E-04 3,372E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 1,717E-04 3,442E-03 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 2,07E-04 4,116E-03 ! regulation of immune effector process GO:0002697 137 71 3,000 2,149E-04 4,238E-03 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 2,000 2,302E-04 4,502E-03 ! response to oxygen radical GO:0000305 11 6 1,000 2,495E-04 4,842E-03 ! neurofilament cytoskeleton organization GO:0060052 12 6 1,000 2,495E-04 4,803E-03 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 2,495E-04 4,765E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 2,495E-04 4,727E-03 ! response to ATP GO:0033198 7 6 1,000 2,495E-04 4,69E-03 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 2,495E-04 4,654E-03 ! regulation of collagen metabolic process GO:0010712 9 6 1,000 2,495E-04 4,618E-03 ! neural nucleus development GO:0048857 14 6 1,000 2,495E-04 4,583E-03 ! astrocyte development GO:0014002 15 6 1,000 2,495E-04 4,548E-03 ! response to copper ion GO:0046688 10 6 1,000 2,495E-04 4,514E-03 ! neutrophil homeostasis GO:0001780 10 6 1,000 2,495E-04 4,48E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 2,495E-04 4,447E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,495E-04 4,414E-03 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 2,495E-04 4,382E-03 GO:0045625|regulation of T-helper 1 cell differentiation, ! removal of superoxide radicals GO:0019430 11 6 1,000 2,495E-04 4,35E-03 ! organ or tissue specific immune response GO:0002251 7 6 1,000 2,495E-04 4,319E-03 ! negative regulation of smooth muscle contraction GO:0045986 12 6 1,000 2,495E-04 4,288E-03 ! regulation of transcription factor activity GO:0051090 126 74 3,000 2,521E-04 4,301E-03 GO:0090046|regulation of transcription regulator activity, ! acute-phase response GO:0006953 49 30 2,000 2,55E-04 4,32E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 3,096E-04 5,21E-03 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 3,096E-04 5,174E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 3,396E-04 5,635E-03 GO:0060326|cell chemotaxis, ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 1,000 3,484E-04 5,741E-03 GO:0045346|regulation of MHC class II biosynthetic process, ! regulation of lipid catabolic process GO:0050994 15 7 1,000 3,484E-04 5,702E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,484E-04 5,664E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 3,484E-04 5,626E-03 ! positive regulation of isotype switching GO:0045830 15 7 1,000 3,484E-04 5,588E-03 GO:0045911|positive regulation of DNA recombination, ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 3,484E-04 5,551E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 3,484E-04 5,515E-03 ! positive regulation of activated T cell proliferation GO:0042104 12 7 1,000 3,484E-04 5,479E-03 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 1,000 3,484E-04 5,443E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 3,484E-04 5,408E-03 ! negative regulation of osteoclast differentiation GO:0045671 10 7 1,000 3,484E-04 5,373E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 3,484E-04 5,339E-03 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 3,484E-04 5,305E-03 ! muscle adaptation GO:0043500 14 7 1,000 3,484E-04 5,272E-03 ! retina homeostasis GO:0001895 12 7 1,000 3,484E-04 5,239E-03 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 3,484E-04 5,206E-03 ! glial cell differentiation GO:0010001 63 34 2,000 3,713E-04 5,515E-03 ! cytokine production GO:0001816 59 35 2,000 4,049E-04 5,977E-03 ! regulation of proteolysis GO:0030162 72 36 2,000 4,404E-04 6,461E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,633E-04 6,755E-03 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 1,000 4,633E-04 6,715E-03 ! astrocyte differentiation GO:0048708 18 8 1,000 4,633E-04 6,674E-03 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 1,000 4,633E-04 6,635E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 4,633E-04 6,595E-03 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 4,633E-04 6,557E-03 ! negative regulation of muscle contraction GO:0045932 15 8 1,000 4,633E-04 6,518E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 4,633E-04 6,48E-03 ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 4,633E-04 6,443E-03 ! regulation of protein transport GO:0051223 154 87 3,000 4,68E-04 6,471E-03 GO:0070201|regulation of establishment of protein localization, ! cellular response to insulin stimulus GO:0032869 82 37 2,000 4,778E-04 6,57E-03 ! mammary gland development GO:0030879 86 39 2,000 5,587E-04 7,637E-03 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 2,000 5,587E-04 7,594E-03 ! cell proliferation in forebrain GO:0021846 15 9 1,000 5,94E-04 8,029E-03 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 5,94E-04 7,985E-03 ! cerebral cortex cell migration GO:0021795 15 9 1,000 5,94E-04 7,94E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 5,94E-04 7,896E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 5,94E-04 7,853E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 5,94E-04 7,81E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 5,94E-04 7,768E-03 ! motor axon guidance GO:0008045 16 9 1,000 5,94E-04 7,726E-03 ! peptidyl-asparagine modification GO:0018196 15 9 1,000 5,94E-04 7,684E-03 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 5,94E-04 7,643E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 5,94E-04 7,602E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 5,94E-04 7,562E-03 ! regulation of membrane potential GO:0042391 164 93 3,000 6,023E-04 7,627E-03 ! gliogenesis GO:0042063 88 41 2,000 6,477E-04 8,16E-03 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 6,477E-04 8,117E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 6,526E-04 8,136E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 6,955E-04 8,625E-03 ! regulation of leukocyte mediated immunity GO:0002703 79 42 2,000 6,955E-04 8,581E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 6,955E-04 8,537E-03 ! regulation of protein localization GO:0032880 176 97 3,000 7,058E-04 8,62E-03 ! interphase GO:0051325 213 98 3,000 7,335E-04 8,913E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,405E-04 8,953E-03 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 7,405E-04 8,909E-03 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 7,405E-04 8,864E-03 ! lens development in camera-type eye GO:0002088 16 10 1,000 7,405E-04 8,82E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 7,405E-04 8,777E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 7,405E-04 8,734E-03 ! copper ion homeostasis GO:0055070 13 10 1,000 7,405E-04 8,691E-03 ! salivary gland development GO:0007431 27 10 1,000 7,405E-04 8,649E-03 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 7,405E-04 8,607E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 7,405E-04 8,566E-03 ! detection of calcium ion GO:0005513 23 10 1,000 7,405E-04 8,525E-03 ! localization within membrane GO:0051668 20 10 1,000 7,405E-04 8,484E-03 ! leukocyte migration GO:0050900 68 45 2,000 8,52E-04 9,715E-03 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 2,000 8,52E-04 9,669E-03 ! telencephalon cell migration GO:0022029 20 11 1,000 9,027E-04 0,01019622 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 9,027E-04 0,01014857 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 9,027E-04 0,01010137 ! negative regulation of proteolysis GO:0045861 25 11 1,000 9,027E-04 0,01005461 ! temperature homeostasis GO:0001659 17 11 1,000 9,027E-04 0,01000827 ! regulation of organ growth GO:0046620 13 11 1,000 9,027E-04 9,962E-03 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 9,027E-04 9,917E-03 ! regulation of isotype switching GO:0045191 22 11 1,000 9,027E-04 9,872E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 9,027E-04 9,827E-03 ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 9,027E-04 9,783E-03 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 9,027E-04 9,739E-03 ! thymus development GO:0048538 27 11 1,000 9,027E-04 9,696E-03 ! positive regulation of JNK cascade GO:0046330 23 11 1,000 9,027E-04 9,652E-03 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 9,027E-04 9,61E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 9,087E-04 9,631E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 9,087E-04 9,589E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 9,087E-04 9,547E-03 ! JNK cascade GO:0007254 91 47 2,000 9,677E-04 0,01012341 ! regulation of JNK cascade GO:0046328 94 47 2,000 9,677E-04 0,01007959 ! protein homooligomerization GO:0051260 76 47 2,000 9,677E-04 0,01003614 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,029E-03 0,0106274 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 1,029E-03 0,01058198 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,08E-03 0,01106015 ! cytokine biosynthetic process GO:0042089 21 12 1,000 1,08E-03 0,01101328 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,08E-03 0,01096682 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,08E-03 0,01092074 ! forebrain cell migration GO:0021885 21 12 1,000 1,08E-03 0,01087504 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 1,000 1,08E-03 0,01082973 ! cranial nerve development GO:0021545 20 12 1,000 1,08E-03 0,01078479 ! histone acetylation GO:0016573 26 12 1,000 1,08E-03 0,01074023 ! autonomic nervous system development GO:0048483 24 12 1,000 1,08E-03 0,01069603 ! gland morphogenesis GO:0022612 29 12 1,000 1,08E-03 0,01065219 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,08E-03 0,01060872 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,08E-03 0,01056559 GO:0042130|negative regulation of T cell proliferation, ! regulation of steroid biosynthetic process GO:0050810 17 12 1,000 1,08E-03 0,01052281 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 2,000 1,093E-03 0,01060399 ! endocrine system development GO:0035270 104 49 2,000 1,093E-03 0,0105614 ! viral infectious cycle GO:0019058 99 51 2,000 1,228E-03 0,01181905 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 1,273E-03 0,01220492 ! positive regulation of lipid metabolic process GO:0045834 25 13 1,000 1,273E-03 0,01215649 ! endocrine pancreas development GO:0031018 22 13 1,000 1,273E-03 0,01210844 ! plasma membrane organization GO:0007009 24 13 1,000 1,273E-03 0,01206077 ! cell-cell junction assembly GO:0007043 27 13 1,000 1,273E-03 0,01201347 ! cytokine metabolic process GO:0042107 22 13 1,000 1,273E-03 0,01196654 ! exocrine system development GO:0035272 32 13 1,000 1,273E-03 0,01191998 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,273E-03 0,01187378 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 1,273E-03 0,01182794 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 1,273E-03 0,01178244 ! positive regulation of growth GO:0045927 90 52 2,000 1,299E-03 0,01197815 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 2,000 1,45E-03 0,01331252 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,481E-03 0,01355281 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 1,481E-03 0,01350147 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,481E-03 0,01345052 ! embryo implantation GO:0007566 30 14 1,000 1,481E-03 0,01339996 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 1,481E-03 0,01334977 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 1,481E-03 0,01329996 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,481E-03 0,01325052 ! regulation of protein catabolic process GO:0042176 116 55 2,000 1,529E-03 0,01362255 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 1,529E-03 0,01357228 ! regulation of intracellular transport GO:0032386 101 57 2,000 1,695E-03 0,01499165 ! positive regulation of cell size GO:0045793 27 15 1,000 1,705E-03 0,01502451 ! superoxide anion generation GO:0042554 20 15 1,000 1,705E-03 0,01496967 ! pituitary gland development GO:0021983 29 15 1,000 1,705E-03 0,01491524 ! regulation of exocytosis GO:0017157 22 15 1,000 1,705E-03 0,0148612 ! copper ion transport GO:0006825 20 15 1,000 1,705E-03 0,01480755 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 1,705E-03 0,01475428 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 1,705E-03 0,0147014 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 1,705E-03 0,0146489 ! muscle maintenance GO:0046716 26 15 1,000 1,705E-03 0,01459676 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,943E-03 0,01657815 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 1,943E-03 0,01651957 ! fructose metabolic process GO:0006000 25 16 1,000 1,943E-03 0,0164614 ! intermediate filament-based process GO:0045103 32 16 1,000 1,943E-03 0,01640364 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,943E-03 0,01634629 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,943E-03 0,01628933 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 1,000 1,943E-03 0,01623277 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 1,964E-03 0,01635434 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,06E-03 0,01708981 ! viral reproductive process GO:0022415 126 62 2,000 2,158E-03 0,0178437 ! limbic system development GO:0021761 36 17 1,000 2,196E-03 0,01809634 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 2,196E-03 0,01803457 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,196E-03 0,01797323 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,196E-03 0,01791231 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 2,196E-03 0,01785179 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 1,000 2,196E-03 0,01779168 ! regulation of mitosis GO:0007088 105 63 2,000 2,259E-03 0,01824123 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 2,000 2,259E-03 0,01818022 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 2,464E-03 0,01976222 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 2,464E-03 0,01969657 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,464E-03 0,01963135 ! positive regulation of proteolysis GO:0045862 31 18 1,000 2,464E-03 0,01956656 ! regulation of steroid metabolic process GO:0019218 30 18 1,000 2,464E-03 0,0195022 ! nerve development GO:0021675 28 18 1,000 2,464E-03 0,01943825 ! regulation of cellular response to stress GO:0080135 128 67 2,000 2,693E-03 0,02117552 ! homeostasis of number of cells GO:0048872 114 67 2,000 2,693E-03 0,02110654 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 2,747E-03 0,02145569 ! skin development GO:0043588 36 19 1,000 2,747E-03 0,02138625 ! lipid phosphorylation GO:0046834 35 19 1,000 2,747E-03 0,02131727 ! cerebral cortex development GO:0021987 36 19 1,000 2,747E-03 0,02124872 ! neuromuscular junction development GO:0007528 34 19 1,000 2,747E-03 0,02118062 ! response to lipopolysaccharide GO:0032496 30 19 1,000 2,747E-03 0,02111295 ! heart process GO:0003015 30 19 1,000 2,747E-03 0,02104571 GO:0060047|heart contraction, ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 2,747E-03 0,0209789 ! cell-cell junction organization GO:0045216 35 19 1,000 2,747E-03 0,02091251 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 2,747E-03 0,02084654 ! peptide hormone secretion GO:0030072 31 19 1,000 2,747E-03 0,02078098 ! viral reproduction GO:0016032 134 68 2,000 2,809E-03 0,02118677 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,044E-03 0,02288403 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,044E-03 0,02281274 ! pancreas development GO:0031016 35 20 1,000 3,044E-03 0,02274189 ! peptide secretion GO:0002790 35 20 1,000 3,044E-03 0,02267148 ! diencephalon development GO:0021536 34 20 1,000 3,044E-03 0,02260151 ! detection of chemical stimulus GO:0009593 37 20 1,000 3,044E-03 0,02253197 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 3,044E-03 0,02246285 ! inner ear receptor cell differentiation GO:0060113 37 20 1,000 3,044E-03 0,02239416 ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,044E-03 0,02232588 ! acute inflammatory response GO:0002526 113 72 2,000 3,303E-03 0,02415687 ! regulation of caspase activity GO:0043281 122 72 2,000 3,303E-03 0,02408367 ! hormone secretion GO:0046879 38 21 1,000 3,355E-03 0,02438666 ! axis specification GO:0009798 38 21 1,000 3,355E-03 0,02431321 ! ovarian follicle development GO:0001541 35 21 1,000 3,355E-03 0,02424019 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 3,355E-03 0,02416762 ! cell aging GO:0007569 44 21 1,000 3,355E-03 0,02409548 ! vasodilation GO:0042311 39 21 1,000 3,355E-03 0,02402376 ! positive regulation of locomotion GO:0040017 39 21 1,000 3,355E-03 0,02395248 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 3,355E-03 0,02388161 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 3,355E-03 0,02381116 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 3,355E-03 0,02374113 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 3,355E-03 0,02367151 ! meiosis GO:0007126 121 74 2,000 3,569E-03 0,02510847 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 3,569E-03 0,02503526 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 3,681E-03 0,02574229 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 3,681E-03 0,02566767 ! regulation of chemotaxis GO:0050920 40 22 1,000 3,681E-03 0,02559349 ! regeneration GO:0031099 41 22 1,000 3,681E-03 0,02551973 ! mechanoreceptor differentiation GO:0042490 40 22 1,000 3,681E-03 0,0254464 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,681E-03 0,02537349 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 3,681E-03 0,02530099 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,681E-03 0,02522891 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 3,681E-03 0,02515723 ! activation of JUN kinase activity GO:0007257 42 22 1,000 3,681E-03 0,02508597 ! meiotic cell cycle GO:0051321 122 75 2,000 3,707E-03 0,02519288 ! lymphocyte differentiation GO:0030098 167 75 2,000 3,707E-03 0,02512192 ! regulation of catabolic process GO:0009894 161 76 2,000 3,848E-03 0,02600328 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 4,02E-03 0,02709435 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,02E-03 0,02701867 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 4,02E-03 0,02694341 ! regulation of DNA recombination GO:0000018 48 23 1,000 4,02E-03 0,02686857 ! response to ethanol GO:0045471 46 23 1,000 4,02E-03 0,02679414 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,02E-03 0,02672012 ! platelet activation GO:0030168 37 23 1,000 4,02E-03 0,02664651 ! hormone transport GO:0009914 40 23 1,000 4,02E-03 0,02657331 ! negative regulation of catabolic process GO:0009895 50 23 1,000 4,02E-03 0,02650051 ! protein oligomerization GO:0051259 139 78 2,000 4,139E-03 0,02720839 ! regulation of peptidase activity GO:0052547 134 79 2,000 4,29E-03 0,0281215 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,374E-03 0,02859704 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 4,374E-03 0,02851954 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 4,374E-03 0,02844246 ! regulation of behavior GO:0050795 43 24 1,000 4,374E-03 0,02836579 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 4,374E-03 0,02828954 GO:0002708|positive regulation of lymphocyte mediated immunity, ! pallium development GO:0021543 49 24 1,000 4,374E-03 0,0282137 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,374E-03 0,02813826 ! response to metal ion GO:0010038 140 80 2,000 4,443E-03 0,02850886 ! T cell activation GO:0042110 168 81 2,000 4,601E-03 0,02943888 ! regulation of neuron differentiation GO:0045664 167 81 2,000 4,601E-03 0,02936079 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 4,742E-03 0,03018025 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,742E-03 0,03010062 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 4,742E-03 0,03002141 ! negative regulation of cell development GO:0010721 73 25 1,000 4,742E-03 0,02994262 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 1,000 4,742E-03 0,02986423 ! hydrogen peroxide metabolic process GO:0042743 33 25 1,000 4,742E-03 0,02978626 ! somitogenesis GO:0001756 43 25 1,000 4,742E-03 0,02970869 ! positive regulation of protein secretion GO:0050714 36 25 1,000 4,742E-03 0,02963152 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 4,761E-03 0,02967675 ! positive regulation of nuclear division GO:0051785 40 26 1,000 5,123E-03 0,0318493 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 5,123E-03 0,03176721 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 5,123E-03 0,03168555 ! response to inorganic substance GO:0010035 153 86 2,000 5,437E-03 0,03354135 ! mitochondrion organization GO:0007005 148 86 2,000 5,437E-03 0,03345557 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,518E-03 0,03386749 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 5,518E-03 0,03378131 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,518E-03 0,03369557 ! protein amino acid acylation GO:0043543 55 27 1,000 5,518E-03 0,03361026 ! superoxide metabolic process GO:0006801 38 27 1,000 5,518E-03 0,03352539 ! fat cell differentiation GO:0045444 50 27 1,000 5,518E-03 0,03344094 ! glutathione metabolic process GO:0006749 39 27 1,000 5,518E-03 0,03335692 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 5,518E-03 0,03327332 ! negative regulation of protein modification process GO:0031400 60 28 1,000 5,926E-03 0,03564745 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 5,926E-03 0,03555856 ! regulation of cell cycle process GO:0010564 149 90 2,000 6,167E-03 0,03691265 ! translational initiation GO:0006413 65 29 1,000 6,348E-03 0,03790119 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 6,348E-03 0,03780737 ! regulation of peptide secretion GO:0002791 47 29 1,000 6,348E-03 0,03771402 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,348E-03 0,03762113 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 6,348E-03 0,0375287 ! tissue homeostasis GO:0001894 48 29 1,000 6,348E-03 0,03743671 GO:0048871|multicellular organismal homeostasis, ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 6,752E-03 0,03971969 ! cell junction assembly GO:0034329 78 30 1,000 6,784E-03 0,03980822 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 6,784E-03 0,03971137 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 6,784E-03 0,03961498 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 6,784E-03 0,03951906 ! neurotransmitter secretion GO:0007269 48 30 1,000 6,784E-03 0,0394236 ! response to heat GO:0009408 50 30 1,000 6,784E-03 0,03932861 ! inner ear morphogenesis GO:0042472 47 31 1,000 7,232E-03 0,0418276 ! ovulation cycle process GO:0022602 49 31 1,000 7,232E-03 0,04172729 ! peptide transport GO:0015833 55 31 1,000 7,232E-03 0,04162747 ! iron ion homeostasis GO:0055072 54 31 1,000 7,232E-03 0,04152812 ! positive regulation of immune effector process GO:0002699 67 31 1,000 7,232E-03 0,04142924 ! leukocyte differentiation GO:0002521 202 96 2,000 7,368E-03 0,04211052 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 7,694E-03 0,04386406 ! response to hydrogen peroxide GO:0042542 50 32 1,000 7,694E-03 0,04376036 ! regulation of axonogenesis GO:0050770 75 32 1,000 7,694E-03 0,04365715 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 7,694E-03 0,04355443 ! ovulation cycle GO:0042698 51 32 1,000 7,694E-03 0,04345219 ! hindbrain development GO:0030902 61 32 1,000 7,694E-03 0,04335043 ! positive regulation of catabolic process GO:0009896 64 32 1,000 7,694E-03 0,04324914 ! skeletal muscle tissue development GO:0007519 186 99 2,000 8,017E-03 0,0449636 GO:0060538|skeletal muscle organ development, ! negative regulation of protein transport GO:0051224 69 33 1,000 8,168E-03 0,04570269 ! cell cycle arrest GO:0007050 213 100 2,000 8,241E-03 0,04600252 ! placenta development GO:0001890 53 34 1,000 8,655E-03 0,04820504 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 9,155E-03 0,05087212 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 9,155E-03 0,0507549 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 9,155E-03 0,05063822 ! female gonad development GO:0008585 58 35 1,000 9,155E-03 0,05052208 ! telencephalon development GO:0021537 68 35 1,000 9,155E-03 0,05040647 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 9,155E-03 0,05029138 ! calcium-mediated signaling GO:0019722 62 35 1,000 9,155E-03 0,05017683 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 9,668E-03 0,05286599 ! cell junction organization GO:0034330 86 36 1,000 9,668E-03 0,05274612 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 9,668E-03 0,05262678 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 9,668E-03 0,05250799 ! negative regulation of cell activation GO:0050866 65 36 1,000 9,668E-03 0,05238972 ! maintenance of protein location in cell GO:0032507 86 36 1,000 9,668E-03 0,05227199 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 0,01019308 0,05498777 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01019308 0,05486475 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01073062 0,0576292 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,01073062 0,05750085 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01073062 0,05737307 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01073062 0,05724585 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01073062 0,0571192 ! ear morphogenesis GO:0042471 60 39 1,000 0,01128046 0,05991343 ! segmentation GO:0035282 67 39 1,000 0,01128046 0,05978146 ! negative regulation of binding GO:0051100 72 40 1,000 0,01184248 0,06262197 ! maintenance of protein location GO:0045185 91 40 1,000 0,01184248 0,06248464 ! protein amino acid N-linked glycosylation GO:0006487 65 41 1,000 0,01241656 0,06537035 ! T cell differentiation GO:0030217 81 41 1,000 0,01241656 0,06522762 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01241656 0,06508552 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01300262 0,06800934 ! regulation of tube size GO:0035150 71 42 1,000 0,01300262 0,06786182 GO:0050880|regulation of blood vessel size, ! regulation of protein secretion GO:0050708 71 42 1,000 0,01300262 0,06771493 ! glucose transport GO:0015758 65 43 1,000 0,01360053 0,07067576 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01360053 0,07052344 ! hexose transport GO:0008645 67 44 1,000 0,01421019 0,0735263 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 0,01421019 0,07336852 ! B cell differentiation GO:0030183 107 44 1,000 0,01421019 0,07321141 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01421019 0,07305498 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01421019 0,07289921 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 0,01483151 0,0759247 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01546436 0,0789963 ! positive regulation of defense response GO:0031349 76 47 1,000 0,01610866 0,0821132 ! response to calcium ion GO:0051592 81 47 1,000 0,01610866 0,0819396 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01610866 0,08176673 ! cellular component disassembly GO:0022411 86 48 1,000 0,01676429 0,08491553 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,01676429 0,08473713 ! peptide metabolic process GO:0006518 76 49 1,000 0,01743115 0,08792316 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01743115 0,08773922 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,01810914 0,09096158 ! regulation of ossification GO:0030278 117 50 1,000 0,01810914 0,09077208 ! inner ear development GO:0048839 79 50 1,000 0,01810914 0,09058337 ! histone modification GO:0016570 91 50 1,000 0,01810914 0,09039543 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01810914 0,09020828 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,01879817 0,09344708 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,01879817 0,09325441 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,01949812 0,09652772 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01949812 0,09632951 ! synapse organization GO:0050808 85 52 1,000 0,01949812 0,09613211 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,0202089 0,09943274 ! regulation of translational initiation GO:0006446 82 53 1,000 0,0202089 0,09922981 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,0202089 0,09902772 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0204189 0,09985341 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0204189 0,09965087 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0204189 0,09944914 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0204189 0,09924824 ! neuron fate determination GO:0048664 7 5 0,000 0,0204189 0,09904814 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0204189 0,09884885 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0204189 0,09865036 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0204189 0,09845266 ! polyol transport GO:0015791 12 5 0,000 0,0204189 0,09825575 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0204189 0,09805963 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0204189 0,0978643 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0204189 0,09766974 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0204189 0,09747595 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,0204189 0,09728292 ! female meiosis GO:0007143 7 5 0,000 0,0204189 0,09709067 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0204189 0,09689917 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0204189 0,09670842 ! cobalt ion transport GO:0006824 11 5 0,000 0,0204189 0,09651842 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0204189 0,09632917 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0204189 0,09614066 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0204189 0,09595289 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0204189 0,09576584 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0204189 0,09557953 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0204189 0,09539394 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0204189 0,09520906 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0204189 0,09502491 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0204189 0,09484146 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0204189 0,09465872 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0204189 0,09447669 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0204189 0,09429535 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,0204189 0,09411471 ! negative chemotaxis GO:0050919 14 5 0,000 0,0204189 0,09393476 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0204189 0,09375549 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0204189 0,09357691 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0204189 0,09339901 ! behavioral response to pain GO:0048266 9 5 0,000 0,0204189 0,09322178 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0204189 0,09304522 ! Notch receptor processing GO:0007220 8 5 0,000 0,0204189 0,09286933 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0204189 0,09269411 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0204189 0,09251954 ! micturition GO:0060073 9 5 0,000 0,0204189 0,09234563 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0204189 0,09217238 ! copulation GO:0007620 9 5 0,000 0,0204189 0,09199977 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0204189 0,09182781 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0204189 0,09165649 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0204189 0,0914858 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0204189 0,09131576 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0204189 0,09114634 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0204189 0,09097755 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0204189 0,09080938 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0204189 0,09064184 ! grooming behavior GO:0007625 6 5 0,000 0,0204189 0,09047491 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0204189 0,0903086 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0204189 0,09014289 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0204189 0,0899778 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0204189 0,0898133 ! lymph vessel development GO:0001945 10 5 0,000 0,0204189 0,08964941 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0204189 0,08948611 ! endochondral ossification GO:0001958 16 5 0,000 0,0204189 0,08932341 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0204189 0,0891613 ! parathyroid gland development GO:0060017 13 5 0,000 0,0204189 0,08899978 ! anagen GO:0042640 6 5 0,000 0,0204189 0,08883884 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0204189 0,08867848 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0204189 0,0885187 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0204189 0,08835949 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0204189 0,08820086 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0204189 0,08804279 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0204189 0,08788529 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0204189 0,08772835 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0204189 0,08757197 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0204189 0,08741615 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0204189 0,08726088 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0204189 0,08710617 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0204189 0,08695199 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0204189 0,08679837 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0204189 0,08664529 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0204189 0,08649274 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0204189 0,08634073 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0204189 0,08618926 ! histidine catabolic process GO:0006548 6 5 0,000 0,0204189 0,08603831 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0204189 0,0858879 ! valine metabolic process GO:0006573 10 5 0,000 0,0204189 0,08573801 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0204189 0,08558864 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0204189 0,08543979 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0204189 0,08529145 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0204189 0,08514363 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0204189 0,08499633 ! polyol catabolic process GO:0046174 7 5 0,000 0,0204189 0,08484953 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0204189 0,08470324 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0204189 0,08455745 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0204189 0,08441216 ! muscle cell migration GO:0014812 8 5 0,000 0,0204189 0,08426737 ! mitochondrial fission GO:0000266 8 5 0,000 0,0204189 0,08412308 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0204189 0,08397928 ! mRNA transcription GO:0009299 9 5 0,000 0,0204189 0,08383597 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0204189 0,08369315 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0204189 0,08355081 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0204189 0,08340896 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0204189 0,08326759 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0204189 0,0831267 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0204189 0,08298628 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0204189 0,08284634 ! response to food GO:0032094 6 5 0,000 0,0204189 0,08270686 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0204189 0,08256786 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0204189 0,08242932 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0204189 0,08229125 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0204189 0,08215364 ! forebrain neuron development GO:0021884 13 5 0,000 0,0204189 0,08201649 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0204189 0,0818798 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0204189 0,08174356 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0204189 0,08160777 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0204189 0,08147243 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0204189 0,08133754 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0204189 0,0812031 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0204189 0,0810691 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0204189 0,08093555 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0204189 0,08080243 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0204189 0,08066975 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0204189 0,0805375 ! basic amino acid transport GO:0015802 11 5 0,000 0,0204189 0,08040569 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0204189 0,08027431 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0204189 0,08014336 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0204189 0,08001283 ! depyrimidination GO:0045008 10 5 0,000 0,0204189 0,07988273 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0204189 0,07975305 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0204189 0,07962379 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0204189 0,07949495 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0204189 0,07936652 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0204189 0,07923851 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0204189 0,07911091 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0204189 0,07898373 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0204189 0,07885695 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0204189 0,07873057 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0204189 0,0786046 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0204189 0,07847904 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0204189 0,07835387 ! response to arsenic GO:0046685 10 5 0,000 0,0204189 0,0782291 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0204189 0,07810473 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0204189 0,07798076 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0204189 0,07785717 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0204189 0,07773398 ! response to cadmium ion GO:0046686 7 5 0,000 0,0204189 0,07761118 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0204189 0,07748877 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0204189 0,07736674 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0204189 0,07724509 ! decidualization GO:0046697 11 5 0,000 0,0204189 0,07712383 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0204189 0,07700294 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0204189 0,07688244 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0204189 0,07676231 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0204189 0,07664255 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0204189 0,07652317 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0204189 0,07640416 ! neural tube patterning GO:0021532 7 5 0,000 0,0204189 0,07628552 ! embryonic cleavage GO:0040016 6 5 0,000 0,0204189 0,07616725 ! peroxisome fission GO:0016559 5 5 0,000 0,0204189 0,07604935 ! histone demethylation GO:0016577 10 5 0,000 0,0204189 0,0759318 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0204189 0,07581463 ! mitotic recombination GO:0006312 9 5 0,000 0,0204189 0,07569781 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0204189 0,07558135 ! metaphase plate congression GO:0051310 7 5 0,000 0,0204189 0,07546525 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0204189 0,0753495 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,0204189 0,07523412 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0204189 0,07511908 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0204189 0,07500439 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0204189 0,07489006 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0204189 0,07477607 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0204189 0,07466243 ! plasminogen activation GO:0031639 5 5 0,000 0,0204189 0,07454913 ! B cell homeostasis GO:0001782 13 5 0,000 0,0204189 0,07443618 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0204189 0,07432357 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0204189 0,07421129 ! metaphase GO:0051323 8 5 0,000 0,0204189 0,07409936 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0204189 0,07398777 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0204189 0,07387651 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0204189 0,07376558 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0204189 0,07365499 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0204189 0,07354473 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0204189 0,07343479 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0204189 0,07332519 ! response to redox state GO:0051775 5 5 0,000 0,0204189 0,07321591 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0204189 0,07310696 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0204189 0,07299833 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0204189 0,07289003 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0204189 0,07278204 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0204189 0,07267437 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0204189 0,07256703 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0204189 0,07246 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0204189 0,07235328 ! striatum development GO:0021756 9 5 0,000 0,0204189 0,07224688 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0204189 0,07214079 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0204189 0,07203501 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0204189 0,07192954 ! glial cell migration GO:0008347 11 5 0,000 0,0204189 0,07182438 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0204189 0,07171953 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0204189 0,07161498 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0204189 0,07151074 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0204189 0,0714068 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0204189 0,07130316 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0204189 0,07119982 ! neuroprotection GO:0043526 6 5 0,000 0,0204189 0,07109678 ! neural plate development GO:0001840 8 5 0,000 0,0204189 0,07099404 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0204189 0,0708916 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0204189 0,07078945 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0204189 0,07068759 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0204189 0,07058603 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0204189 0,07048476 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0204189 0,07038378 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0204189 0,07028309 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0204189 0,07018268 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0204189 0,07008256 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0204189 0,06998273 ! spindle assembly GO:0051225 6 5 0,000 0,0204189 0,06988318 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0204189 0,06978392 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0204189 0,06968493 ! drug metabolic process GO:0017144 6 5 0,000 0,0204189 0,06958623 ! stem cell division GO:0017145 11 5 0,000 0,0204189 0,0694878 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0204189 0,06938966 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0204189 0,06929179 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0204189 0,06919419 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0204189 0,06909687 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02093041 0,07072832 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02166255 0,0730997 ! aging GO:0007568 103 55 1,000 0,02166255 0,07299732 ! RNA elongation GO:0006354 79 55 1,000 0,02166255 0,07289523 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02240522 0,07528904 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02240522 0,07518404 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,02315832 0,07760296 ! muscle fiber development GO:0048747 112 57 1,000 0,02315832 0,07749503 ! lipid modification GO:0030258 97 57 1,000 0,02315832 0,0773874 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02315832 0,07728006 ! maintenance of location GO:0051235 118 57 1,000 0,02315832 0,07717303 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,02392177 0,07960687 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02392177 0,07949692 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02445278 0,08114949 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02445278 0,08103772 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02445278 0,08092625 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02445278 0,08081508 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02445278 0,08070423 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02445278 0,08059367 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02445278 0,08048342 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02445278 0,08037347 ! sleep GO:0030431 13 6 0,000 0,02445278 0,08026382 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02445278 0,08015447 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02445278 0,08004542 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02445278 0,07993666 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02445278 0,0798282 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02445278 0,07972003 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02445278 0,07961215 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02445278 0,07950457 ! forebrain regionalization GO:0021871 8 6 0,000 0,02445278 0,07939728 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02445278 0,07929027 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02445278 0,07918355 ! response to zinc ion GO:0010043 9 6 0,000 0,02445278 0,07907713 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02445278 0,07897098 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02445278 0,07886512 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02445278 0,07875955 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02445278 0,07865425 ! malate metabolic process GO:0006108 11 6 0,000 0,02445278 0,07854924 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02445278 0,07844451 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02445278 0,07834006 ! protein refolding GO:0042026 15 6 0,000 0,02445278 0,07823588 ! opsonization GO:0008228 8 6 0,000 0,02445278 0,07813198 ! mating behavior GO:0007617 7 6 0,000 0,02445278 0,07802836 ! neuron remodeling GO:0016322 15 6 0,000 0,02445278 0,07792501 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02445278 0,07782193 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02445278 0,07771913 ! equilibrioception GO:0050957 14 6 0,000 0,02445278 0,0776166 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02445278 0,07751434 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02445278 0,07741234 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02445278 0,07731062 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02445278 0,07720916 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02445278 0,07710797 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02445278 0,07700704 ! toxin metabolic process GO:0009404 11 6 0,000 0,02445278 0,07690638 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02445278 0,07680598 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02445278 0,07670584 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02445278 0,07660597 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02445278 0,07650635 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02445278 0,07640699 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02445278 0,07630789 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02445278 0,07620904 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02445278 0,07611045 ! thymic T cell selection GO:0045061 12 6 0,000 0,02445278 0,07601212 ! protein lipoylation GO:0009249 10 6 0,000 0,02445278 0,07591404 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02445278 0,07581621 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02445278 0,07571864 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02445278 0,07562131 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02445278 0,07552424 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02445278 0,07542741 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02445278 0,07533083 ! response to pH GO:0009268 10 6 0,000 0,02445278 0,0752345 ! hyperosmotic response GO:0006972 9 6 0,000 0,02445278 0,07513842 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02445278 0,07504258 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02445278 0,07494698 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02445278 0,07485163 ! urea metabolic process GO:0019627 7 6 0,000 0,02445278 0,07475652 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! neutrophil activation GO:0042119 8 6 0,000 0,02445278 0,07466165 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02445278 0,07456702 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02445278 0,07447263 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02445278 0,07437848 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02445278 0,07428457 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02445278 0,0741909 ! neuron apoptosis GO:0051402 9 6 0,000 0,02445278 0,07409746 ! nucleoside salvage GO:0043174 9 6 0,000 0,02445278 0,07400425 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02445278 0,07391128 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02445278 0,07381855 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02445278 0,07372604 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02445278 0,07363377 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02445278 0,07354173 ! carnitine transport GO:0015879 10 6 0,000 0,02445278 0,07344991 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02445278 0,07335833 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02445278 0,07326698 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02445278 0,07317585 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02445278 0,07308495 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02445278 0,07299427 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02445278 0,07290382 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02445278 0,07281359 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02445278 0,07272359 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02445278 0,0726338 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02445278 0,07254424 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02445278 0,0724549 ! response to UV-C GO:0010225 11 6 0,000 0,02445278 0,07236578 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02445278 0,07227688 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02445278 0,0721882 ! interaction with symbiont GO:0051702 13 6 0,000 0,02445278 0,07209973 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02445278 0,07201148 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02445278 0,07192345 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02445278 0,07183563 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02445278 0,07174803 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02445278 0,07166064 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02445278 0,07157346 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02445278 0,07148649 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02445278 0,07139973 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02445278 0,07131319 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02445278 0,07122685 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02445278 0,07114073 ! hair follicle maturation GO:0048820 7 6 0,000 0,02445278 0,07105481 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02445278 0,0709691 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02445278 0,07088359 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02445278 0,07079829 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02445278 0,0707132 ! subpallium development GO:0021544 10 6 0,000 0,02445278 0,07062831 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02445278 0,07054362 ! histone ubiquitination GO:0016574 8 6 0,000 0,02445278 0,07045914 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02445278 0,07037486 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02445278 0,07029078 ! G2 phase GO:0051319 16 6 0,000 0,02445278 0,0702069 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02445278 0,07012322 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02445278 0,07003974 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02445278 0,06995646 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02445278 0,06987337 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02445278 0,06979049 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02445278 0,0697078 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02445278 0,0696253 ! receptor internalization GO:0031623 10 6 0,000 0,02445278 0,069543 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02445278 0,0694609 GO:0031272|regulation of pseudopodium assembly, ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02445278 0,06937899 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,02445278 0,06929727 ! protein destabilization GO:0031648 9 6 0,000 0,02445278 0,06921574 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02445278 0,06913441 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02445278 0,06905326 ! regulation of viral transcription GO:0046782 10 6 0,000 0,02445278 0,06897231 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02445278 0,06889155 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02445278 0,06881097 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02445278 0,06873059 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02445278 0,06865039 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02445278 0,06857037 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02445278 0,06849055 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02445278 0,06841091 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02445278 0,06833145 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02445278 0,06825218 ! catecholamine transport GO:0051937 9 6 0,000 0,02445278 0,0681731 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02445278 0,06809419 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02445278 0,06801547 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02445278 0,06793693 ! maternal placenta development GO:0001893 12 6 0,000 0,02445278 0,06785857 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02445278 0,06778039 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02445278 0,0677024 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02445278 0,06762458 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02445278 0,06754694 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02445278 0,06746947 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02445278 0,06739219 ! positive regulation of secretion GO:0051047 95 59 1,000 0,02469545 0,06798313 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02469545 0,06790543 ! DNA catabolic process GO:0006308 86 59 1,000 0,02469545 0,06782791 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,02547928 0,06990096 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02547928 0,06982135 ! camera-type eye development GO:0043010 116 60 1,000 0,02547928 0,06974192 ! ear development GO:0043583 103 62 1,000 0,02707699 0,07403095 ! gonad development GO:0008406 98 62 1,000 0,02707699 0,07394692 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,02789068 0,07608275 ! tRNA transcription GO:0009304 14 7 0,000 0,02847017 0,07757558 ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02847017 0,07748783 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02847017 0,07740027 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02847017 0,07731291 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02847017 0,07722575 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02847017 0,07713878 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02847017 0,07705201 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02847017 0,07696544 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02847017 0,07687906 ! prostate gland development GO:0030850 13 7 0,000 0,02847017 0,07679287 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02847017 0,07670688 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02847017 0,07662107 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02847017 0,07653546 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02847017 0,07645004 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02847017 0,07636482 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02847017 0,07627978 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02847017 0,07619493 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02847017 0,07611027 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02847017 0,07602579 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02847017 0,07594151 ! glycolipid transport GO:0046836 10 7 0,000 0,02847017 0,07585741 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02847017 0,0757735 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02847017 0,07568977 ! neuron adhesion GO:0007158 12 7 0,000 0,02847017 0,07560622 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02847017 0,07552287 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02847017 0,07543969 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02847017 0,0753567 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02847017 0,07527389 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02847017 0,07519126 ! mRNA stabilization GO:0048255 18 7 0,000 0,02847017 0,07510882 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02847017 0,07502655 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02847017 0,07494446 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02847017 0,07486256 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02847017 0,07478083 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02847017 0,07469928 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02847017 0,07461791 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02847017 0,07453671 ! lipoprotein transport GO:0042953 14 7 0,000 0,02847017 0,0744557 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02847017 0,07437485 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02847017 0,07429419 ! rhythmic behavior GO:0007622 15 7 0,000 0,02847017 0,07421369 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02847017 0,07413338 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02847017 0,07405323 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02847017 0,07397326 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02847017 0,07389346 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02847017 0,07381384 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02847017 0,07373438 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02847017 0,0736551 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02847017 0,07357598 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02847017 0,07349704 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02847017 0,07341826 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02847017 0,07333966 ! spinal cord patterning GO:0021511 13 7 0,000 0,02847017 0,07326122 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02847017 0,07318295 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02847017 0,07310484 ! adrenal gland development GO:0030325 17 7 0,000 0,02847017 0,07302691 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02847017 0,07294914 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02847017 0,07287153 ! ovulation GO:0030728 9 7 0,000 0,02847017 0,07279409 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02847017 0,07271681 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02847017 0,0726397 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02847017 0,07256275 ! microtubule nucleation GO:0007020 20 7 0,000 0,02847017 0,07248597 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02847017 0,07240934 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02847017 0,07233288 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02847017 0,07225658 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02847017 0,07218044 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02847017 0,07210446 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02847017 0,07202864 ! galactose metabolic process GO:0006012 13 7 0,000 0,02847017 0,07195298 ! vesicle fusion GO:0006906 17 7 0,000 0,02847017 0,07187748 ! response to dietary excess GO:0002021 8 7 0,000 0,02847017 0,07180214 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02847017 0,07172695 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02847017 0,07165192 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02847017 0,07157705 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02847017 0,07150234 ! organ growth GO:0035265 15 7 0,000 0,02847017 0,07142778 ! purine salvage GO:0043101 10 7 0,000 0,02847017 0,07135337 ! nucleoside transport GO:0015858 8 7 0,000 0,02847017 0,07127913 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02847017 0,07120503 ! parturition GO:0007567 14 7 0,000 0,02847017 0,07113109 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02847017 0,0710573 ! rRNA modification GO:0000154 14 7 0,000 0,02847017 0,07098367 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02847017 0,07091019 ! spindle checkpoint GO:0031577 15 7 0,000 0,02847017 0,07083686 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02847017 0,07076368 ! macrophage differentiation GO:0030225 11 7 0,000 0,02847017 0,07069065 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02847017 0,07061777 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02847017 0,07054505 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02847017 0,07047247 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02847017 0,07040004 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02847017 0,07032776 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02847017 0,07025563 ! fibrinolysis GO:0042730 10 7 0,000 0,02847017 0,07018365 ! eating behavior GO:0042755 7 7 0,000 0,02847017 0,07011181 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02847017 0,07004012 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02847017 0,06996858 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02847017 0,06989718 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02847017 0,06982593 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02847017 0,06975483 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02847017 0,06968387 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02847017 0,06961305 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02847017 0,06954238 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02847017 0,06947185 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02847017 0,06940146 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02847017 0,06933121 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02847017 0,06926111 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02847017 0,06919115 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02847017 0,06912133 ! regulation of meiosis GO:0040020 12 7 0,000 0,02847017 0,06905165 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02847017 0,06898211 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02847017 0,06891272 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02847017 0,06884346 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02847017 0,06877434 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02847017 0,06870536 ! transcription termination GO:0006353 13 7 0,000 0,02847017 0,06863651 ! response to tumor cell GO:0002347 13 7 0,000 0,02847017 0,06856781 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02847017 0,06849924 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02847017 0,06843081 ! anaphase GO:0051322 17 7 0,000 0,02847017 0,06836251 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02847017 0,06829436 ! axonal fasciculation GO:0007413 18 7 0,000 0,02847017 0,06822633 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02847017 0,06815845 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02847017 0,0680907 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02847017 0,06802308 ! diuresis GO:0030146 12 7 0,000 0,02847017 0,06795559 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02847017 0,06788825 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02847017 0,06782103 ! antibiotic transport GO:0042891 9 7 0,000 0,02847017 0,06775395 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02847017 0,067687 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02847017 0,06762018 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02847017 0,06755349 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02847017 0,06748694 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02847017 0,06742051 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02847017 0,06735422 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02847017 0,06728805 ! lymph node development GO:0048535 10 7 0,000 0,02847017 0,06722202 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02847017 0,06715612 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02847017 0,06709034 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02847017 0,0670247 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02847017 0,06695918 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02847017 0,06689379 ! adult feeding behavior GO:0008343 9 7 0,000 0,02847017 0,06682853 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02847017 0,06676339 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02847017 0,06669838 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02847017 0,0666335 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02847017 0,06656875 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02847017 0,06650412 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02847017 0,06643961 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02847017 0,06637523 ! protein prenylation GO:0018342 18 7 0,000 0,02847017 0,06631098 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02847017 0,06624685 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02847017 0,06618284 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,02871415 0,06668556 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,02871415 0,06662125 GO:0048609|reproductive process in a multicellular organism, ! cell projection assembly GO:0030031 120 66 1,000 0,03039 0,07044157 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,03124222 0,07234723 ! lung development GO:0030324 144 67 1,000 0,03124222 0,07227766 ! adaptive immune response GO:0002250 119 67 1,000 0,03124222 0,07220823 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,03210383 0,07412841 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03210383 0,07405734 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03247116 0,07483296 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03247116 0,07476135 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03247116 0,07468988 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03247116 0,07461854 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03247116 0,07454734 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03247116 0,07447628 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03247116 0,07440535 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03247116 0,07433455 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03247116 0,07426389 ! meiotic prophase I GO:0007128 13 8 0,000 0,03247116 0,07419336 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03247116 0,07412297 ! oligopeptide transport GO:0006857 15 8 0,000 0,03247116 0,07405271 ! UTP metabolic process GO:0046051 8 8 0,000 0,03247116 0,07398259 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03247116 0,07391259 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03247116 0,07384273 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03247116 0,07377301 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03247116 0,07370341 ! succinate metabolic process GO:0006105 14 8 0,000 0,03247116 0,07363394 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03247116 0,07356461 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03247116 0,0734954 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03247116 0,07342633 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03247116 0,07335738 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03247116 0,07328857 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03247116 0,07321988 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03247116 0,07315132 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03247116 0,07308289 ! reflex GO:0060004 16 8 0,000 0,03247116 0,07301459 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03247116 0,07294642 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03247116 0,07287837 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03247116 0,07281045 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03247116 0,07274266 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03247116 0,07267499 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03247116 0,07260745 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03247116 0,07254003 ! pigment granule organization GO:0048753 16 8 0,000 0,03247116 0,07247274 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03247116 0,07240557 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03247116 0,07233853 ! histidine metabolic process GO:0006547 16 8 0,000 0,03247116 0,07227161 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03247116 0,07220482 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03247116 0,07213815 ! glycine catabolic process GO:0006546 13 8 0,000 0,03247116 0,0720716 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03247116 0,07200517 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03247116 0,07193887 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,03247116 0,07187269 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03247116 0,07180663 ! melanin metabolic process GO:0006582 15 8 0,000 0,03247116 0,07174069 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03247116 0,07167487 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03247116 0,07160918 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03247116 0,0715436 ! macrophage activation GO:0042116 12 8 0,000 0,03247116 0,07147815 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03247116 0,07141281 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03247116 0,07134759 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03247116 0,07128249 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03247116 0,07121751 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03247116 0,07115265 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03247116 0,07108791 ! osteoblast development GO:0002076 16 8 0,000 0,03247116 0,07102328 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03247116 0,07095878 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03247116 0,07089439 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03247116 0,07083011 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03247116 0,07076595 ! response to UV-B GO:0010224 16 8 0,000 0,03247116 0,07070191 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03247116 0,07063799 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03247116 0,07057418 ! intermediate filament organization GO:0045109 12 8 0,000 0,03247116 0,07051048 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03247116 0,0704469 ! cellular extravasation GO:0045123 12 8 0,000 0,03247116 0,07038343 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03247116 0,07032008 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03247116 0,07025685 ! response to antibiotic GO:0046677 11 8 0,000 0,03247116 0,07019372 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03247116 0,07013071 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03247116 0,07006781 ! DNA topological change GO:0006265 12 8 0,000 0,03247116 0,07000503 ! response to tropane GO:0014073 15 8 0,000 0,03247116 0,06994236 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03247116 0,0698798 ! melanosome transport GO:0032402 13 8 0,000 0,03247116 0,06981735 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03247116 0,06975501 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03247116 0,06969279 ! mast cell activation GO:0045576 14 8 0,000 0,03247116 0,06963067 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03247116 0,06956867 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03247116 0,06950677 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03247116 0,06944499 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03247116 0,06938332 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03247116 0,06932175 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03247116 0,0692603 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03247116 0,06919895 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03247116 0,06913771 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03247116 0,06907658 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03247116 0,06901556 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03247116 0,06895465 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03247116 0,06889384 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03247116 0,06883314 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03247116 0,06877255 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03247116 0,06871206 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03247116 0,06865168 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03247116 0,06859141 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03247116 0,06853124 ! hormone catabolic process GO:0042447 17 8 0,000 0,03247116 0,06847118 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03247116 0,06841122 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03247116 0,06835137 ! ATP catabolic process GO:0006200 11 8 0,000 0,03247116 0,06829162 ! blastocyst growth GO:0001832 19 8 0,000 0,03247116 0,06823198 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03247116 0,06817244 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03247116 0,068113 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03247116 0,06805367 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03247116 0,06799444 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03247116 0,06793532 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03247116 0,06787629 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03247116 0,06781737 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03247116 0,06775855 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03247116 0,06769984 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03247116 0,06764122 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03247116 0,06758271 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03247116 0,0675243 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03247116 0,06746599 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03247116 0,06740778 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03247116 0,06734967 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03247116 0,06729166 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03247116 0,06723375 ! negative regulation of cell size GO:0045792 134 69 1,000 0,03297475 0,06821775 ! respiratory tube development GO:0030323 150 70 1,000 0,03385489 0,0699784 ! reproductive structure development GO:0048608 113 71 1,000 0,03474416 0,07175489 ! humoral immune response GO:0006959 109 71 1,000 0,03474416 0,07169335 ! B cell activation GO:0042113 160 71 1,000 0,03474416 0,07163191 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03564247 0,07342104 ! carbohydrate transport GO:0008643 110 72 1,000 0,03564247 0,07335824 ! respiratory system development GO:0060541 153 72 1,000 0,03564247 0,07329554 ! regulation of developmental growth GO:0048638 15 9 0,000 0,0364558 0,07490407 ! axon extension GO:0048675 15 9 0,000 0,0364558 0,07484015 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0364558 0,07477635 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0364558 0,07471266 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0364558 0,07464907 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0364558 0,0745856 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0364558 0,07452223 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0364558 0,07445896 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0364558 0,07439581 ! phosphate transport GO:0006817 19 9 0,000 0,0364558 0,07433276 ! reproductive behavior GO:0019098 19 9 0,000 0,0364558 0,07426982 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0364558 0,07420699 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0364558 0,07414426 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0364558 0,07408164 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0364558 0,07401912 ! GTP metabolic process GO:0046039 9 9 0,000 0,0364558 0,07395671 ! RNA methylation GO:0001510 15 9 0,000 0,0364558 0,07389441 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0364558 0,07383221 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0364558 0,07377011 ! artery development GO:0060840 24 9 0,000 0,0364558 0,07370812 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0364558 0,07364623 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0364558 0,07358445 ! chemosensory behavior GO:0007635 20 9 0,000 0,0364558 0,07352277 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0364558 0,07346119 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0364558 0,07339972 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0364558 0,07333835 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0364558 0,07327708 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0364558 0,07321591 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0364558 0,07315485 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0364558 0,07309388 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0364558 0,07303302 ! protein targeting to ER GO:0045047 22 9 0,000 0,0364558 0,07297226 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0364558 0,0729116 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0364558 0,07285105 ! T cell selection GO:0045058 23 9 0,000 0,0364558 0,07279059 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0364558 0,07273023 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0364558 0,07266998 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0364558 0,07260982 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0364558 0,07254976 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0364558 0,0724898 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0364558 0,07242994 ! mannose metabolic process GO:0006013 13 9 0,000 0,0364558 0,07237018 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0364558 0,07231052 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0364558 0,07225096 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0364558 0,07219149 ! receptor clustering GO:0043113 18 9 0,000 0,0364558 0,07213212 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0364558 0,07207285 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0364558 0,07201368 ! ruffle organization GO:0031529 15 9 0,000 0,0364558 0,0719546 ! retinol metabolic process GO:0042572 18 9 0,000 0,0364558 0,07189562 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0364558 0,07183674 ! behavioral fear response GO:0001662 22 9 0,000 0,0364558 0,07177795 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0364558 0,07171926 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0364558 0,07166067 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0364558 0,07160217 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,0364558 0,07154377 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0364558 0,07148546 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0364558 0,07142725 ! segment specification GO:0007379 13 9 0,000 0,0364558 0,07136913 ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0364558 0,07131111 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0364558 0,07125318 ! response to amine stimulus GO:0014075 13 9 0,000 0,0364558 0,07119534 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0364558 0,0711376 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0364558 0,07107995 ! erythrocyte development GO:0048821 15 9 0,000 0,0364558 0,0710224 ! gas homeostasis GO:0033483 16 9 0,000 0,0364558 0,07096494 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0364558 0,07090757 ! renal water homeostasis GO:0003091 14 9 0,000 0,0364558 0,07085029 ! postreplication repair GO:0006301 22 9 0,000 0,0364558 0,07079311 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0364558 0,07073602 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0364558 0,07067902 ! icosanoid secretion GO:0032309 15 9 0,000 0,0364558 0,07062211 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0364558 0,07056529 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0364558 0,07050857 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0364558 0,07045194 ! regulation of cell division GO:0051302 15 9 0,000 0,0364558 0,07039539 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0364558 0,07033894 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0364558 0,07028258 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0364558 0,07022631 ! sterol catabolic process GO:0016127 11 9 0,000 0,0364558 0,07017013 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0364558 0,07011404 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0364558 0,07005804 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0364558 0,07000212 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0364558 0,0699463 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0364558 0,06989057 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0364558 0,06983492 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0364558 0,06977936 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0364558 0,0697239 ! purine base metabolic process GO:0006144 21 9 0,000 0,0364558 0,06966852 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0364558 0,06961322 ! pigment granule transport GO:0051904 17 9 0,000 0,0364558 0,06955802 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0364558 0,0695029 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0364558 0,06944787 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0364558 0,06939293 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0364558 0,06933807 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0364558 0,0692833 ! mitochondrion localization GO:0051646 15 9 0,000 0,0364558 0,06922862 ! learning or memory GO:0007611 147 73 1,000 0,03654973 0,06935225 ! regulation of blood pressure GO:0008217 125 73 1,000 0,03654973 0,0692976 ! axon guidance GO:0007411 139 73 1,000 0,03654973 0,06924304 ! transition metal ion transport GO:0000041 126 74 1,000 0,03746586 0,07092279 ! neurotransmitter transport GO:0006836 123 74 1,000 0,03746586 0,07086704 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,03746586 0,07081137 ! eye development GO:0001654 143 74 1,000 0,03746586 0,07075578 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,03839077 0,07244565 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,03839077 0,07238887 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,03839077 0,07233219 ! rhythmic process GO:0048511 128 75 1,000 0,03839077 0,07227559 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,03932437 0,07397533 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,03932437 0,07391753 ! defense response to bacterium GO:0042742 89 76 1,000 0,03932437 0,07385983 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04042417 0,07586626 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04042417 0,07580713 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04042417 0,07574809 ! synapsis GO:0007129 13 10 0,000 0,04042417 0,07568914 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04042417 0,07563028 ! N-glycan processing GO:0006491 20 10 0,000 0,04042417 0,07557152 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04042417 0,07551284 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04042417 0,07545426 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04042417 0,07539577 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04042417 0,07533737 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04042417 0,07527906 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04042417 0,07522084 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04042417 0,07516271 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04042417 0,07510467 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04042417 0,07504671 ! androgen metabolic process GO:0008209 17 10 0,000 0,04042417 0,07498885 ! phospholipid efflux GO:0033700 16 10 0,000 0,04042417 0,07493108 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04042417 0,0748734 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04042417 0,0748158 ! lung alveolus development GO:0048286 26 10 0,000 0,04042417 0,0747583 ! pathogenesis GO:0009405 13 10 0,000 0,04042417 0,07470088 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04042417 0,07464355 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04042417 0,07458631 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04042417 0,07452915 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04042417 0,07447208 ! endoderm development GO:0007492 16 10 0,000 0,04042417 0,07441511 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04042417 0,07435821 ! arginine catabolic process GO:0006527 13 10 0,000 0,04042417 0,07430141 ! proline metabolic process GO:0006560 13 10 0,000 0,04042417 0,07424469 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04042417 0,07418806 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04042417 0,07413151 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04042417 0,07407505 ! V(D)J recombination GO:0033151 28 10 0,000 0,04042417 0,07401868 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04042417 0,07396239 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04042417 0,07390619 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04042417 0,07385007 ! B cell proliferation GO:0042100 18 10 0,000 0,04042417 0,07379404 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04042417 0,07373809 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04042417 0,07368223 ! multicellular organism growth GO:0035264 18 10 0,000 0,04042417 0,07362645 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04042417 0,07357076 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04042417 0,07351515 ! epithelial cell development GO:0002064 20 10 0,000 0,04042417 0,07345962 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04042417 0,07340418 ! macroautophagy GO:0016236 17 10 0,000 0,04042417 0,07334883 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04042417 0,07329355 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04042417 0,07323836 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04042417 0,07318325 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04042417 0,07312823 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04042417 0,07307329 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04042417 0,07301843 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04042417 0,07296365 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04042417 0,07290895 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04042417 0,07285434 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04042417 0,07279981 ! response to dsRNA GO:0043331 20 10 0,000 0,04042417 0,07274536 ! DNA ligation GO:0006266 19 10 0,000 0,04042417 0,07269099 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04042417 0,0726367 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04042417 0,07258249 ! melanosome localization GO:0032400 16 10 0,000 0,04042417 0,07252837 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04042417 0,07247432 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04042417 0,07242036 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04042417 0,07236648 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04042417 0,07231267 ! mRNA cleavage GO:0006379 17 10 0,000 0,04042417 0,07225895 ! protein sumoylation GO:0016925 15 10 0,000 0,04042417 0,0722053 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04042417 0,07215174 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04042417 0,07209825 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04042417 0,07204485 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04042417 0,07199152 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04042417 0,07193827 ! prophase GO:0051324 15 10 0,000 0,04042417 0,0718851 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04042417 0,07183201 ! apical protein localization GO:0045176 15 10 0,000 0,04042417 0,071779 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04042417 0,07172606 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,04042417 0,07167321 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04042417 0,07162043 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04042417 0,07156773 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04042417 0,0715151 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04042417 0,07146256 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04042417 0,07141009 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04042417 0,0713577 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04042417 0,07130538 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04042417 0,07125314 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 0,000 0,04042417 0,07120098 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04042417 0,0711489 ! blastocyst formation GO:0001825 17 10 0,000 0,04042417 0,07109689 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04042417 0,07104495 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04042417 0,0709931 ! activation of innate immune response GO:0002218 12 10 0,000 0,04042417 0,07094131 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04042417 0,07088961 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04042417 0,07083798 ! response to nicotine GO:0035094 20 10 0,000 0,04042417 0,07078642 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04042417 0,07073494 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04042417 0,07068353 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04042417 0,0706322 ! blood coagulation GO:0007596 146 78 1,000 0,04121731 0,07196578 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,04121731 0,07191359 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,04217647 0,07353376 ! response to hypoxia GO:0001666 171 81 1,000 0,04411977 0,07686616 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04437632 0,07725718 ! respiratory burst GO:0045730 17 11 0,000 0,04437632 0,07720131 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04437632 0,07714553 ! neuron fate specification GO:0048665 17 11 0,000 0,04437632 0,07708983 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04437632 0,07703421 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04437632 0,07697867 ! thyroid gland development GO:0030878 26 11 0,000 0,04437632 0,07692321 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04437632 0,07686783 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04437632 0,07681253 ! response to pain GO:0048265 24 11 0,000 0,04437632 0,07675731 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04437632 0,07670217 ! T cell proliferation GO:0042098 26 11 0,000 0,04437632 0,07664711 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04437632 0,07659212 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04437632 0,07653722 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04437632 0,07648239 ! bone resorption GO:0045453 16 11 0,000 0,04437632 0,07642764 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04437632 0,07637297 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04437632 0,07631838 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04437632 0,07626387 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04437632 0,07620943 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04437632 0,07615508 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04437632 0,0761008 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04437632 0,07604659 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04437632 0,07599247 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04437632 0,07593842 ! lipid digestion GO:0044241 18 11 0,000 0,04437632 0,07588445 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04437632 0,07583055 ! UV protection GO:0009650 19 11 0,000 0,04437632 0,07577673 ! adult heart development GO:0007512 14 11 0,000 0,04437632 0,07572299 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04437632 0,07566932 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04437632 0,07561573 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04437632 0,07556222 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04437632 0,07550878 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04437632 0,07545542 ! pigment granule localization GO:0051875 20 11 0,000 0,04437632 0,07540213 ! vasoconstriction GO:0042310 18 11 0,000 0,04437632 0,07534892 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04437632 0,07529578 ! embryonic axis specification GO:0000578 18 11 0,000 0,04437632 0,07524272 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04437632 0,07518973 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04437632 0,07513682 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04437632 0,07508398 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04437632 0,07503121 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04437632 0,07497852 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04437632 0,07492591 ! zymogen activation GO:0031638 15 11 0,000 0,04437632 0,07487336 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04437632 0,0748209 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04437632 0,0747685 ! nucleosome positioning GO:0016584 15 11 0,000 0,04437632 0,07471618 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04437632 0,07466393 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04437632 0,07461175 ! acid secretion GO:0046717 18 11 0,000 0,04437632 0,07455965 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04437632 0,07450762 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04437632 0,07445566 ! oocyte differentiation GO:0009994 18 11 0,000 0,04437632 0,07440378 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04437632 0,07435196 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,04437632 0,07430022 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04437632 0,07424855 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04437632 0,07419695 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04437632 0,07414543 ! embryonic gut development GO:0048566 15 11 0,000 0,04437632 0,07409397 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04437632 0,07404259 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04437632 0,07399128 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04437632 0,07394004 ! defense response to fungus GO:0050832 13 11 0,000 0,04437632 0,07388887 ! developmental induction GO:0031128 19 11 0,000 0,04437632 0,07383777 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04437632 0,07378674 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04437632 0,07373579 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04437632 0,0736849 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04437632 0,07363408 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04437632 0,07358333 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04437632 0,07353266 ! nucleus localization GO:0051647 19 11 0,000 0,04437632 0,07348205 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04437632 0,07343151 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,04510374 0,07458391 ! response to drug GO:0042493 143 82 1,000 0,04510374 0,07453268 ! response to oxygen levels GO:0070482 176 83 1,000 0,0460958 0,07611977 ! hemostasis GO:0007599 158 84 1,000 0,04709589 0,07771791 ! negative regulation of growth GO:0045926 155 84 1,000 0,04709589 0,07766464 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,04709589 0,07761145 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04831232 0,07956156 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04831232 0,07950714 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,04831232 0,0794528 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04831232 0,07939853 ! virus-host interaction GO:0019048 29 12 0,000 0,04831232 0,07934433 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04831232 0,07929021 ! cartilage condensation GO:0001502 20 12 0,000 0,04831232 0,07923616 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04831232 0,07918218 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04831232 0,07912828 ! protein complex disassembly GO:0043241 27 12 0,000 0,04831232 0,07907445 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04831232 0,0790207 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04831232 0,07896701 ! hippocampus development GO:0021766 26 12 0,000 0,04831232 0,0789134 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04831232 0,07885987 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04831232 0,0788064 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04831232 0,07875301 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04831232 0,07869969 ! drug transport GO:0015893 16 12 0,000 0,04831232 0,07864644 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04831232 0,07859327 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04831232 0,07854016 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04831232 0,07848713 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04831232 0,07843417 ! focal adhesion formation GO:0048041 35 12 0,000 0,04831232 0,07838128 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04831232 0,07832847 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04831232 0,07827572 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04831232 0,07822304 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04831232 0,07817044 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04831232 0,07811791 ! entry into host cell GO:0030260 32 12 0,000 0,04831232 0,07806544 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04831232 0,07801305 ! monoamine transport GO:0015844 18 12 0,000 0,04831232 0,07796073 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04831232 0,07790847 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04831232 0,07785629 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04831232 0,07780418 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04831232 0,07775214 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04831232 0,07770016 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04831232 0,07764826 ! protein homotetramerization GO:0051289 21 12 0,000 0,04831232 0,07759642 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04831232 0,07754466 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04831232 0,07749296 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04831232 0,07744133 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04831232 0,07738978 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04831232 0,07733829 ! fucose catabolic process GO:0019317 22 12 0,000 0,04831232 0,07728686 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04831232 0,07723551 ! histone methylation GO:0016571 26 12 0,000 0,04831232 0,07718423 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04831232 0,07713301 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04831232 0,07708186 ! T cell homeostasis GO:0043029 25 12 0,000 0,04831232 0,07703078 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04831232 0,07697976 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04831232 0,07692882 ! spleen development GO:0048536 22 12 0,000 0,04831232 0,07687794 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04831232 0,07682713 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04831232 0,07677638 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04831232 0,0767257 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04831232 0,07667509 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04831232 0,07662455 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04831232 0,07657407 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04831232 0,07652366 ! response to cold GO:0009409 17 12 0,000 0,04831232 0,07647332 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04831232 0,07642304 ! oxidative phosphorylation GO:0006119 133 86 1,000 0,0491198 0,0776493 ! cellular respiration GO:0045333 135 88 1,000 0,05117481 0,08084478 ! regulation of neurological system process GO:0031644 148 88 1,000 0,05117481 0,08079173 ! cellular defense response GO:0006968 114 89 1,000 0,05221378 0,08237794 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,05221378 0,08232396 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,05221378 0,08227004 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05223224 0,08224527 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05223224 0,08219148 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05223224 0,08213776 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05223224 0,08208411 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05223224 0,08203053 ! lipid localization GO:0010876 28 13 0,000 0,05223224 0,08197702 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,05223224 0,08192358 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05223224 0,08187021 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05223224 0,08181691 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05223224 0,08176368 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05223224 0,08171052 ! methionine metabolic process GO:0006555 27 13 0,000 0,05223224 0,08165742 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05223224 0,0816044 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05223224 0,08155145 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05223224 0,08149856 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! response to X-ray GO:0010165 25 13 0,000 0,05223224 0,08144574 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05223224 0,08139299 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05223224 0,08134031 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05223224 0,0812877 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05223224 0,08123515 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05223224 0,08118267 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05223224 0,08113026 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05223224 0,08107792 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05223224 0,08102565 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05223224 0,08097344 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05223224 0,0809213 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05223224 0,08086923 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05223224 0,08081722 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05223224 0,08076528 ! ribosome assembly GO:0042255 17 13 0,000 0,05223224 0,08071341 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05223224 0,0806616 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05223224 0,08060986 ! chromatin silencing GO:0006342 26 13 0,000 0,05223224 0,08055819 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05223224 0,08050658 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05223224 0,08045504 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05223224 0,08040357 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05223224 0,08035216 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05223224 0,08030082 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05223224 0,08024954 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05223224 0,08019833 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05223224 0,08014718 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05223224 0,0800961 ! embryonic placenta development GO:0001892 23 13 0,000 0,05223224 0,08004508 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05223224 0,07999413 ! insulin secretion GO:0030073 23 13 0,000 0,05223224 0,07994324 ! actin filament polymerization GO:0030041 24 13 0,000 0,05223224 0,07989242 ! acrosome reaction GO:0007340 18 13 0,000 0,05223224 0,07984166 ! ossification GO:0001503 188 90 1,000 0,05326029 0,08136143 ! sex differentiation GO:0007548 145 90 1,000 0,05326029 0,0813098 ! bone development GO:0060348 189 91 1,000 0,05431425 0,08286626 ! sterol metabolic process GO:0016125 152 91 1,000 0,05431425 0,08281375 ! regulation of defense response GO:0031347 149 92 1,000 0,0553756 0,08437853 ! rRNA transcription GO:0009303 25 14 0,000 0,05613615 0,08548328 ! lactation GO:0007595 26 14 0,000 0,05613615 0,08542921 ! reproductive cellular process GO:0048610 20 14 0,000 0,05613615 0,08537521 ! tRNA modification GO:0006400 20 14 0,000 0,05613615 0,08532127 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05613615 0,08526741 ! regulation of S phase GO:0033261 23 14 0,000 0,05613615 0,08521361 ! water transport GO:0006833 21 14 0,000 0,05613615 0,08515988 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05613615 0,08510622 ! non-recombinational repair GO:0000726 25 14 0,000 0,05613615 0,08505263 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05613615 0,0849991 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05613615 0,08494565 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05613615 0,08489225 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05613615 0,08483893 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05613615 0,08478567 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05613615 0,08473248 ! palate development GO:0060021 31 14 0,000 0,05613615 0,08467936 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05613615 0,0846263 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05613615 0,08457331 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05613615 0,08452039 ! arginine metabolic process GO:0006525 17 14 0,000 0,05613615 0,08446753 ! regulation of heart rate GO:0002027 24 14 0,000 0,05613615 0,08441474 ! organic alcohol transport GO:0015850 29 14 0,000 0,05613615 0,08436201 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05613615 0,08430935 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05613615 0,08425675 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 26 14 0,000 0,05613615 0,08420422 ! L-amino acid transport GO:0015807 30 14 0,000 0,05613615 0,08415176 ! bone mineralization GO:0030282 17 14 0,000 0,05613615 0,08409936 ! stem cell development GO:0048864 43 14 0,000 0,05613615 0,08404703 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05613615 0,08399476 ! cerebellum development GO:0021549 21 14 0,000 0,05613615 0,08394256 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05613615 0,08389042 ! response to gamma radiation GO:0010332 28 14 0,000 0,05613615 0,08383835 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05613615 0,08378634 ! cofactor transport GO:0051181 26 14 0,000 0,05613615 0,08373439 ! NADP metabolic process GO:0006739 24 14 0,000 0,05613615 0,08368251 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,05613615 0,0836307 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05613615 0,08357895 ! intestinal absorption GO:0050892 25 14 0,000 0,05613615 0,08352726 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05613615 0,08347563 ! oxygen transport GO:0015671 21 14 0,000 0,05613615 0,08342407 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05613615 0,08337258 ! male genitalia development GO:0030539 24 14 0,000 0,05613615 0,08332115 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05613615 0,08326978 ! regulation of axon extension GO:0030516 37 14 0,000 0,05613615 0,08321847 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05613615 0,08316723 ! female pregnancy GO:0007565 164 94 1,000 0,05752013 0,08516519 ! transcription initiation GO:0006352 153 94 1,000 0,05752013 0,08511281 ! forebrain development GO:0030900 188 95 1,000 0,05860315 0,08666207 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,05860315 0,08660884 ! positive regulation of immune response GO:0050778 156 96 1,000 0,05969325 0,08816573 ! detection of stimulus GO:0051606 151 96 1,000 0,05969325 0,08811164 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0600241 0,08854568 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0600241 0,08849142 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0600241 0,08843723 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0600241 0,08838311 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0600241 0,08832905 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0600241 0,08827506 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0600241 0,08822113 ! sulfate transport GO:0008272 23 15 0,000 0,0600241 0,08816728 ! response to cAMP GO:0051591 22 15 0,000 0,0600241 0,08811348 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0600241 0,08805975 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0600241 0,08800609 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0600241 0,08795249 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0600241 0,08789896 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0600241 0,0878455 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0600241 0,0877921 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0600241 0,08773876 ! vesicle coating GO:0006901 33 15 0,000 0,0600241 0,08768549 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0600241 0,08763228 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0600241 0,08757914 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0600241 0,08752606 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0600241 0,08747304 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0600241 0,08742009 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0600241 0,08736721 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0600241 0,08731439 ! histone deacetylation GO:0016575 20 15 0,000 0,0600241 0,08726163 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0600241 0,08720894 ! tissue regeneration GO:0042246 26 15 0,000 0,0600241 0,0871563 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0600241 0,08710374 ! water homeostasis GO:0030104 27 15 0,000 0,0600241 0,08705123 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0600241 0,08699879 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0600241 0,08694642 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0600241 0,0868941 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0600241 0,08684185 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0600241 0,08678966 ! cell killing GO:0001906 29 15 0,000 0,0600241 0,08673754 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0600241 0,08668547 ! detection of bacterium GO:0016045 18 15 0,000 0,0600241 0,08663347 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0600241 0,08658153 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0600241 0,08652966 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0600241 0,08647784 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0600241 0,08642609 ! peptide hormone processing GO:0016486 23 15 0,000 0,0600241 0,0863744 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,06079035 0,08742474 ! protein ubiquitination GO:0016567 217 97 1,000 0,06079035 0,08737251 ! response to virus GO:0009615 160 98 1,000 0,06189437 0,08890618 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06389617 0,09172685 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06389617 0,09167215 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06389617 0,09161752 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06389617 0,09156295 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06389617 0,09150845 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06389617 0,09145401 ! bone remodeling GO:0046849 27 16 0,000 0,06389617 0,09139964 ! filopodium assembly GO:0046847 32 16 0,000 0,06389617 0,09134533 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06389617 0,09129109 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06389617 0,09123691 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06389617 0,0911828 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06389617 0,09112875 ! startle response GO:0001964 28 16 0,000 0,06389617 0,09107476 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06389617 0,09102084 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06389617 0,09096698 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06389617 0,09091318 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06389617 0,09085945 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06389617 0,09080578 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06389617 0,09075218 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06389617 0,09069864 ! response to osmotic stress GO:0006970 25 16 0,000 0,06389617 0,09064516 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06389617 0,09059175 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06389617 0,09053839 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06389617 0,09048511 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06389617 0,09043188 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06389617 0,09037871 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06389617 0,09032561 ! axon cargo transport GO:0008088 43 16 0,000 0,06389617 0,09027257 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06389617 0,0902196 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06389617 0,09016668 ! DNA replication initiation GO:0006270 27 16 0,000 0,06389617 0,09011383 ! neuron recognition GO:0008038 35 16 0,000 0,06389617 0,09006104 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06389617 0,09000831 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06389617 0,08995564 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06389617 0,08990304 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06389617 0,08985049 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06389617 0,08979801 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06389617 0,08974559 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06389617 0,08969323 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06389617 0,08964093 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06389617 0,08958869 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06389617 0,08953651 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06389617 0,0894844 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06775242 0,09482974 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06775242 0,09477461 ! metencephalon development GO:0022037 30 17 0,000 0,06775242 0,09471954 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06775242 0,09466453 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06775242 0,09460959 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06775242 0,09455471 ! signal complex assembly GO:0007172 41 17 0,000 0,06775242 0,0944999 ! endothelial cell migration GO:0043542 28 17 0,000 0,06775242 0,09444515 ! inositol metabolic process GO:0006020 28 17 0,000 0,06775242 0,09439046 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06775242 0,09433583 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06775242 0,09428127 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06775242 0,09422678 ! adult walking behavior GO:0007628 33 17 0,000 0,06775242 0,09417234 ! heart looping GO:0001947 30 17 0,000 0,06775242 0,09411797 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06775242 0,09406366 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06775242 0,09400941 ! myoblast differentiation GO:0045445 45 17 0,000 0,06775242 0,09395523 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06775242 0,09390111 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06775242 0,09384705 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,06775242 0,09379305 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06775242 0,09373912 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06775242 0,09368524 ! glycine metabolic process GO:0006544 28 17 0,000 0,06775242 0,09363143 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06775242 0,09357768 ! NAD metabolic process GO:0019674 29 17 0,000 0,06775242 0,09352399 ! membrane budding GO:0006900 37 17 0,000 0,06775242 0,09347037 ! DNA integration GO:0015074 29 17 0,000 0,06775242 0,0934168 ! regulation of protein binding GO:0043393 33 17 0,000 0,06775242 0,0933633 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06775242 0,09330986 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06775242 0,09325648 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06775242 0,09320316 ! genitalia development GO:0048806 30 17 0,000 0,06775242 0,0931499 ! neural crest cell migration GO:0001755 37 17 0,000 0,06775242 0,0930967 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06775242 0,09304356 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06775242 0,09299049 ! steroid catabolic process GO:0006706 31 17 0,000 0,06775242 0,09293747 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06775242 0,09288451 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06775242 0,09283162 ! gas transport GO:0015669 25 17 0,000 0,06775242 0,09277878 ! organic cation transport GO:0015695 31 17 0,000 0,06775242 0,09272601 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06775242 0,09267329 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06775242 0,09262064 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06775242 0,09256804 ! microspike assembly GO:0030035 36 17 0,000 0,06775242 0,09251551 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06775242 0,09246303 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06775242 0,09241061 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07159291 0,09759351 ! neuron maturation GO:0042551 42 18 0,000 0,07159291 0,09753824 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07159291 0,09748304 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,07159291 0,09742791 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07159291 0,09737283 ! memory GO:0007613 31 18 0,000 0,07159291 0,09731782 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07159291 0,09726287 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07159291 0,09720798 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07159291 0,09715315 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07159291 0,09709839 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07159291 0,09704368 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07159291 0,09698904 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07159291 0,09693446 ! response to retinoic acid GO:0032526 26 18 0,000 0,07159291 0,09687994 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,07159291 0,09682548 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,07159291 0,09677109 ! response to fungus GO:0009620 21 18 0,000 0,07159291 0,09671675 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07159291 0,09666248 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07159291 0,09660827 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07159291 0,09655411 ! vitamin transport GO:0051180 27 18 0,000 0,07159291 0,09650002 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07159291 0,09644599 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07159291 0,09639202 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07159291 0,09633811 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07159291 0,09628426 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07159291 0,09623047 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07159291 0,09617674 ! protein secretion GO:0009306 39 19 0,000 0,0754177 0,10125837 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0754177 0,10120189 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0754177 0,10114548 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0754177 0,10108913 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0754177 0,10103285 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0754177 0,10097662 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0754177 0,10092046 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0754177 0,10086436 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0754177 0,10080833 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0754177 0,10075236 ! pigmentation during development GO:0048066 41 19 0,000 0,0754177 0,10069644 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0754177 0,10064059 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,0754177 0,10058481 ! heme metabolic process GO:0042168 36 19 0,000 0,0754177 0,10052908 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0754177 0,10047342 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0754177 0,10041782 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0754177 0,10036227 ! peptide cross-linking GO:0018149 37 19 0,000 0,0754177 0,1003068 ! protein export from nucleus GO:0006611 36 19 0,000 0,0754177 0,10025138 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0754177 0,10019602 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0754177 0,10014072 ! visual learning GO:0008542 36 19 0,000 0,0754177 0,10008549 ! cellular pigmentation GO:0033059 36 19 0,000 0,0754177 0,10003032 ! G1 phase GO:0051318 40 19 0,000 0,0754177 0,0999752 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0754177 0,09992015 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0754177 0,09986516 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0754177 0,09981023 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0754177 0,09975536 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0754177 0,09970055 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0754177 0,09964579 ! cilium assembly GO:0042384 37 19 0,000 0,0754177 0,0995911 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07922687 0,10456382 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,07922687 0,10450649 ! positive regulation of ossification GO:0045778 47 20 0,000 0,07922687 0,10444923 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07922687 0,10439203 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,07922687 0,10433489 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07922687 0,10427781 ! response to vitamin GO:0033273 31 20 0,000 0,07922687 0,1042208 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,07922687 0,10416385 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,07922687 0,10410696 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,07922687 0,10405013 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07922687 0,10399337 ! response to alkaloid GO:0043279 38 20 0,000 0,07922687 0,10393666 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07922687 0,10388002 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07922687 0,10382344 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07922687 0,10376692 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,07922687 0,10371047 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,07922687 0,10365407 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,07922687 0,10359774 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07922687 0,10354147 ! body fluid secretion GO:0007589 31 20 0,000 0,07922687 0,10348526 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07922687 0,1034291 ! stem cell differentiation GO:0048863 53 20 0,000 0,07922687 0,10337302 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07922687 0,10331699 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07922687 0,10326102 ! sensory perception of pain GO:0019233 30 20 0,000 0,07922687 0,10320511 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07922687 0,10314926 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07922687 0,10309348 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,07922687 0,10303775 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,07922687 0,10298209 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07922687 0,10292648 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07922687 0,10287093 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07922687 0,10281545 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07922687 0,10276002 ! regulation of glucose import GO:0046324 29 20 0,000 0,07922687 0,10270466 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07922687 0,10264935 ! actin filament-based movement GO:0030048 43 20 0,000 0,07922687 0,1025941 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07922687 0,10253891 ! negative regulation of translation GO:0017148 29 20 0,000 0,07922687 0,10248378 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07922687 0,10242872 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,07922687 0,10237371 ! regulation of cell killing GO:0031341 42 21 0,000 0,08302046 0,10721805 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08302046 0,10716053 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08302046 0,10710307 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08302046 0,10704568 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08302046 0,10698834 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08302046 0,10693107 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08302046 0,10687385 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08302046 0,1068167 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08302046 0,10675961 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08302046 0,10670258 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08302046 0,10664561 ! cytolysis GO:0019835 24 21 0,000 0,08302046 0,1065887 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08302046 0,10653186 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08302046 0,10647507 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08302046 0,10641834 ! oogenesis GO:0048477 36 21 0,000 0,08302046 0,10636168 ! DNA modification GO:0006304 34 21 0,000 0,08302046 0,10630507 ! collagen fibril organization GO:0030199 59 21 0,000 0,08302046 0,10624853 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08302046 0,10619204 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08302046 0,10613562 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08302046 0,10607925 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08302046 0,10602295 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08302046 0,1059667 ! collagen catabolic process GO:0030574 28 21 0,000 0,08302046 0,10591052 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08302046 0,10585439 ! gut development GO:0048565 39 21 0,000 0,08302046 0,10579832 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08679855 0,11055443 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08679855 0,11049594 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08679855 0,11043751 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08679855 0,11037913 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08679855 0,11032083 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08679855 0,11026258 ! keratinization GO:0031424 28 22 0,000 0,08679855 0,11020439 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,08679855 0,11014627 ! sensory perception of taste GO:0050909 28 22 0,000 0,08679855 0,1100882 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,08679855 0,1100302 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08679855 0,10997226 ! vacuolar transport GO:0007034 36 22 0,000 0,08679855 0,10991438 ! lysosome organization GO:0007040 41 22 0,000 0,08679855 0,10985656 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08679855 0,1097988 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,08679855 0,1097411 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08679855 0,10968347 ! fucose metabolic process GO:0006004 39 22 0,000 0,08679855 0,10962589 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08679855 0,10956837 ! ureteric bud development GO:0001657 43 22 0,000 0,08679855 0,10951092 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08679855 0,10945352 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08679855 0,10939619 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08679855 0,10933891 ! sarcomere organization GO:0045214 30 22 0,000 0,08679855 0,1092817 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08679855 0,10922454 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08679855 0,10916745 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08679855 0,10911041 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08679855 0,10905343 ! protein stabilization GO:0050821 39 22 0,000 0,08679855 0,10899651 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09056121 0,11366211 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09056121 0,11360285 ! gluconeogenesis GO:0006094 33 23 0,000 0,09056121 0,11354365 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09056121 0,11348451 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09056121 0,11342543 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09056121 0,11336642 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09056121 0,11330747 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09056121 0,11324858 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09056121 0,11318975 ! visual behavior GO:0007632 42 23 0,000 0,09056121 0,11313098 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,09056121 0,11307227 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09056121 0,11301362 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,09056121 0,11295503 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09056121 0,11289651 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09056121 0,11283804 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09056121 0,11277964 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09056121 0,11272129 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,09056121 0,11266301 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,09056121 0,11260479 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09056121 0,11254662 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09056121 0,11248852 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09056121 0,11243048 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09056121 0,11237249 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09056121 0,11231457 ! fatty acid transport GO:0015908 44 23 0,000 0,09056121 0,1122567 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09056121 0,1121989 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09056121 0,11214115 ! cell-cell recognition GO:0009988 25 23 0,000 0,09056121 0,11208347 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09056121 0,11202584 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09056121 0,11196827 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09056121 0,11191077 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,09430848 0,11648162 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09430848 0,11642186 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,09430848 0,11636215 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09430848 0,11630251 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09430848 0,11624293 ! vesicle docking GO:0048278 47 24 0,000 0,09430848 0,11618341 ! spinal cord development GO:0021510 47 24 0,000 0,09430848 0,11612395 ! vacuole organization GO:0007033 43 24 0,000 0,09430848 0,11606455 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09430848 0,11600521 ! digestive system process GO:0022600 39 24 0,000 0,09430848 0,11594594 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09430848 0,11588672 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09430848 0,11582756 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09430848 0,11576847 ! membrane depolarization GO:0051899 39 24 0,000 0,09430848 0,11570943 ! pentose metabolic process GO:0019321 35 24 0,000 0,09430848 0,11565046 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09430848 0,11559154 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09430848 0,11553269 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09430848 0,11547389 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09430848 0,11541516 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09430848 0,11535648 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09430848 0,11529786 ! regulation of amine transport GO:0051952 40 24 0,000 0,09430848 0,11523931 ! protein tetramerization GO:0051262 52 24 0,000 0,09430848 0,11518081 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09804043 0,11967797 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,09804043 0,11961728 ! phototransduction GO:0007602 33 25 0,000 0,09804043 0,11955666 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09804043 0,11949609 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,09804043 0,11943559 ! sperm motility GO:0030317 31 25 0,000 0,09804043 0,11937514 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,09804043 0,11931476 ! receptor metabolic process GO:0043112 46 25 0,000 0,09804043 0,11925444 ! chromosome condensation GO:0030261 45 25 0,000 0,09804043 0,11919418 ! response to starvation GO:0042594 42 25 0,000 0,09804043 0,11913398 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09804043 0,11907384 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,09804043 0,11901377 ! neural crest cell development GO:0014032 54 25 0,000 0,09804043 0,11895375 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09804043 0,11889379 ! interaction with host GO:0051701 62 25 0,000 0,09804043 0,1188339 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09804043 0,11877406 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09804043 0,11871428 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09804043 0,11865457 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09804043 0,11859491 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09804043 0,11853532 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09804043 0,11847578 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,09804043 0,11841631 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09804043 0,11835689 ! telomere organization GO:0032200 43 25 0,000 0,09804043 0,11829753 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09804043 0,11823824 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09804043 0,118179 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10175714 0,12259773 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10175714 0,12253637 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10175714 0,12247507 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10175714 0,12241383 ! initiation of viral infection GO:0019059 57 26 0,000 0,10175714 0,12235266 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10175714 0,12229154 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10175714 0,12223049 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10175714 0,12216949 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10175714 0,12210856 ! molting cycle process GO:0022404 50 26 0,000 0,10175714 0,12204769 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,10175714 0,12198688 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,10175714 0,12192613 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10175714 0,12186544 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,10175714 0,12180481 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10175714 0,12174424 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,10175714 0,12168373 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,10175714 0,12162328 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10175714 0,12156289 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10175714 0,12150256 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10175714 0,1214423 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10175714 0,12138209 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10175714 0,12132194 ! blastocyst development GO:0001824 49 26 0,000 0,10175714 0,12126185 ! leukocyte proliferation GO:0070661 52 26 0,000 0,10175714 0,12120182 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10175714 0,12114184 ! neuron fate commitment GO:0048663 48 27 0,000 0,10545864 0,1254864 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,10545864 0,12542437 ! iron ion transport GO:0006826 59 27 0,000 0,10545864 0,1253624 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10545864 0,12530049 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10545864 0,12523865 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10545864 0,12517686 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,10545864 0,12511514 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10545864 0,12505347 ! autophagy GO:0006914 41 27 0,000 0,10545864 0,12499187 ! male gonad development GO:0008584 44 27 0,000 0,10545864 0,12493033 ! response to toxin GO:0009636 47 27 0,000 0,10545864 0,12486885 ! primary neural tube formation GO:0014020 51 27 0,000 0,10545864 0,12480743 ! base-excision repair GO:0006284 41 27 0,000 0,10545864 0,12474607 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10545864 0,12468477 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10545864 0,12462353 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,10545864 0,12456235 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10545864 0,12450123 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,10545864 0,12444017 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10545864 0,12437917 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10914502 0,12866385 ! circadian rhythm GO:0007623 50 28 0,000 0,10914502 0,12860085 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10914502 0,1285379 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10914502 0,12847501 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10914502 0,12841219 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,10914502 0,12834943 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,10914502 0,12828672 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10914502 0,12822408 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10914502 0,12816151 ! synaptogenesis GO:0007416 42 28 0,000 0,10914502 0,12809899 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,10914502 0,12803653 ! lipid oxidation GO:0034440 43 28 0,000 0,10914502 0,12797414 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10914502 0,1279118 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,11281633 0,13215 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11281633 0,13208569 ! regulation of pH GO:0006885 43 29 0,000 0,11281633 0,13202145 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11281633 0,13195727 ! catechol metabolic process GO:0009712 54 29 0,000 0,11281633 0,13189315 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,11281633 0,13182909 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11281633 0,13176509 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,11281633 0,13170116 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,11281633 0,13163729 ! cell fate determination GO:0001709 60 29 0,000 0,11281633 0,13157348 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11281633 0,13150974 ! detection of light stimulus GO:0009583 38 29 0,000 0,11281633 0,13144605 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,11281633 0,13138243 ! regulation of coagulation GO:0050818 46 29 0,000 0,11281633 0,13131887 ! phenol metabolic process GO:0018958 55 30 0,000 0,11647263 0,13550926 ! zinc ion transport GO:0006829 45 30 0,000 0,11647263 0,13544377 ! membrane docking GO:0022406 61 30 0,000 0,11647263 0,13537834 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,11647263 0,13531297 ! regulation of innate immune response GO:0045088 51 30 0,000 0,11647263 0,13524766 ! myofibril assembly GO:0030239 47 30 0,000 0,11647263 0,13518242 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,11647263 0,13511724 ! phospholipid transport GO:0015914 51 30 0,000 0,11647263 0,13505212 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,11647263 0,13498707 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,11647263 0,13492208 ! eye morphogenesis GO:0048592 60 30 0,000 0,11647263 0,13485715 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12011399 0,13900637 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12011399 0,13893954 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12011399 0,13887278 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,12011399 0,13880608 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12011399 0,13873944 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12011399 0,13867286 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12011399 0,13860636 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12011399 0,13853991 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12011399 0,13847353 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,12011399 0,13840721 ! mesoderm formation GO:0001707 69 31 0,000 0,12011399 0,13834095 ! natural killer cell activation GO:0030101 45 31 0,000 0,12011399 0,13827476 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,12011399 0,13820863 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12011399 0,13814257 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12011399 0,13807656 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,12011399 0,13801063 GO:0043433|negative regulation of transcription factor activity, ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12374045 0,14210956 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12374045 0,14204176 ! cholesterol transport GO:0030301 56 32 0,000 0,12374045 0,14197402 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,12374045 0,14190635 ! spliceosome assembly GO:0000245 67 32 0,000 0,12374045 0,14183875 ! spindle organization GO:0007051 46 32 0,000 0,12374045 0,1417712 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12374045 0,14170373 ! metanephros development GO:0001656 74 32 0,000 0,12374045 0,14163631 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12374045 0,14156896 ! response to ionizing radiation GO:0010212 65 32 0,000 0,12374045 0,14150168 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,12374045 0,14143446 ! muscle cell development GO:0055001 49 32 0,000 0,12374045 0,1413673 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,12374045 0,1413002 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12374045 0,14123317 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,12374045 0,14116621 ! BMP signaling pathway GO:0030509 64 32 0,000 0,12374045 0,1410993 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12374045 0,14103246 ! gene silencing GO:0016458 65 32 0,000 0,12374045 0,14096569 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,12735209 0,14501142 ! post-embryonic development GO:0009791 69 33 0,000 0,12735209 0,14494283 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,12735209 0,14487429 ! protein targeting to membrane GO:0006612 68 33 0,000 0,12735209 0,14480583 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,12735209 0,14473743 ! ceramide metabolic process GO:0006672 64 33 0,000 0,12735209 0,14466909 ! formation of primary germ layer GO:0001704 72 33 0,000 0,12735209 0,14460082 ! cell fate specification GO:0001708 52 33 0,000 0,12735209 0,14453261 ! sterol transport GO:0015918 57 33 0,000 0,12735209 0,14446447 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,12735209 0,14439639 ! adult locomotory behavior GO:0008344 59 33 0,000 0,12735209 0,14432837 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,12735209 0,14426042 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,13094897 0,14826504 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13094897 0,1481953 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,13094897 0,14812563 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,13094897 0,14805602 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,13094897 0,14798648 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13094897 0,147917 ! mismatch repair GO:0006298 46 34 0,000 0,13094897 0,14784759 ! spermatid development GO:0007286 63 34 0,000 0,13094897 0,14777824 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,13094897 0,14770896 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13094897 0,14763974 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,13094897 0,14757059 ! regulation of muscle development GO:0048634 70 35 0,000 0,13453113 0,15153647 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,13453113 0,15146556 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,13453113 0,15139472 ! odontogenesis GO:0042476 66 35 0,000 0,13453113 0,15132394 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,13453113 0,15125323 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,13453113 0,15118258 ! neural tube formation GO:0001841 67 35 0,000 0,13453113 0,151112 ! vesicle localization GO:0051648 64 35 0,000 0,13453113 0,15104149 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,13809865 0,15497451 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,13809865 0,15490226 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! sphingoid metabolic process GO:0046519 70 36 0,000 0,13809865 0,15483008 ! positive regulation of cell development GO:0010720 80 36 0,000 0,13809865 0,15475797 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,13809865 0,15468592 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,13809865 0,15461394 ! aerobic respiration GO:0009060 55 36 0,000 0,13809865 0,15454203 ! embryonic organ development GO:0048568 57 36 0,000 0,13809865 0,15447018 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,13809865 0,1543984 ! RNA export from nucleus GO:0006405 56 37 0,000 0,14165159 0,15829713 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,14165159 0,15822364 ! meiosis I GO:0007127 65 37 0,000 0,14165159 0,15815022 ! sister chromatid segregation GO:0000819 58 37 0,000 0,14165159 0,15807686 ! actomyosin structure organization GO:0031032 62 37 0,000 0,14165159 0,15800358 ! organic anion transport GO:0015711 68 37 0,000 0,14165159 0,15793036 ! tissue remodeling GO:0048771 76 37 0,000 0,14165159 0,15785721 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,14165159 0,15778413 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,14165159 0,15771111 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,14165159 0,15763817 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,14165159 0,15756529 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,14165159 0,15749247 ! glycogen metabolic process GO:0005977 61 37 0,000 0,14165159 0,15741973 ! pigment metabolic process GO:0042440 80 37 0,000 0,14165159 0,15734705 ! spermatid differentiation GO:0048515 66 37 0,000 0,14165159 0,15727444 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,14518999 0,16112874 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,14518999 0,16105446 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,14518999 0,16098024 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,14518999 0,16090609 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,14518999 0,16083201 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,14518999 0,16075799 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,14518999 0,16068405 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,14518999 0,16061017 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,14518999 0,16053636 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,14518999 0,16046262 ! glucan metabolic process GO:0044042 62 38 0,000 0,14518999 0,16038894 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,14871392 0,16420638 ! learning GO:0007612 77 39 0,000 0,14871392 0,16413106 ! organic ether metabolic process GO:0018904 55 39 0,000 0,14871392 0,1640558 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,14871392 0,16398062 ! ion transmembrane transport GO:0034220 66 39 0,000 0,14871392 0,1639055 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,14871392 0,16383045 ! RNA modification GO:0009451 57 39 0,000 0,14871392 0,16375547 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,14871392 0,16368056 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,15222345 0,16746668 ! feeding behavior GO:0007631 59 40 0,000 0,15222345 0,16739014 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,15222345 0,16731367 ! mesenchymal cell development GO:0014031 87 40 0,000 0,15222345 0,16723727 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,15222345 0,16716094 ! cytokinesis GO:0000910 72 40 0,000 0,15222345 0,16708468 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,15571862 0,17084314 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,15571862 0,17076527 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,15571862 0,17068747 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,15571862 0,17060975 ! female gamete generation GO:0007292 61 41 0,000 0,15571862 0,17053209 ! polyol metabolic process GO:0019751 66 41 0,000 0,15571862 0,17045451 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,1591995 0,17418554 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1591995 0,17410636 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,1591995 0,17402726 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1591995 0,17394823 ! neuron migration GO:0001764 79 42 0,000 0,1591995 0,17386927 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,16266614 0,17757474 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,16266614 0,17749421 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,16266614 0,17741375 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,16266614 0,17733336 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,16266614 0,17725305 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,16266614 0,17717281 ! neural tube development GO:0021915 77 43 0,000 0,16266614 0,17709264 ! striated muscle contraction GO:0006941 77 43 0,000 0,16266614 0,17701254 ! phagocytosis GO:0006909 90 43 0,000 0,16266614 0,17693252 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,16266614 0,17685257 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,16611861 0,18052455 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,16611861 0,18044305 ! male sex differentiation GO:0046661 76 44 0,000 0,16611861 0,18036163 ! biopolymer methylation GO:0043414 84 44 0,000 0,16611861 0,18028027 ! developmental growth GO:0048589 82 44 0,000 0,16611861 0,18019899 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,16955695 0,18384588 ! glycolysis GO:0006096 65 45 0,000 0,16955695 0,18376307 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,16955695 0,18368033 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,16955695 0,18359767 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,16955695 0,18351508 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,16955695 0,18343256 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,16955695 0,18335012 ! cell growth GO:0016049 84 45 0,000 0,16955695 0,18326775 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,17298123 0,18688497 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,17298123 0,18680109 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,17298123 0,18671729 ! pigmentation GO:0043473 100 46 0,000 0,17298123 0,18663356 ! endosome transport GO:0016197 108 47 0,000 0,1763915 0,19022768 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1763915 0,19014245 ! methylation GO:0032259 90 47 0,000 0,1763915 0,1900573 ! mitochondrial transport GO:0006839 82 48 0,000 0,17978783 0,19363004 ! Notch signaling pathway GO:0007219 96 48 0,000 0,17978783 0,1935434 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,17978783 0,19345685 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,17978783 0,19337037 ! activation of caspase activity GO:0006919 84 48 0,000 0,17978783 0,19328396 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,17978783 0,19319764 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,18317026 0,19674448 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,18317026 0,19665669 ! regulation of ion transport GO:0043269 77 49 0,000 0,18317026 0,19656897 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,18317026 0,19648134 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,18317026 0,19639378 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,18317026 0,1963063 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,18317026 0,19621889 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,18317026 0,19613157 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,18317026 0,19604432 ! neuromuscular process GO:0050905 99 50 0,000 0,18653885 0,1995609 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,18653885 0,19947221 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,18989366 0,20296942 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,18989366 0,20287929 ! excretion GO:0007588 83 51 0,000 0,18989366 0,20278924 ! chromatin remodeling GO:0006338 109 51 0,000 0,18989366 0,20269927 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,18989366 0,20260938 ! vesicle organization GO:0016050 107 51 0,000 0,18989366 0,20251957 ! regulation of cell shape GO:0008360 125 51 0,000 0,18989366 0,20242984 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,18989366 0,20234019 ! membrane fusion GO:0006944 110 52 0,000 0,19323475 0,20580913 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,19323475 0,20571806 ! amino acid activation GO:0043038 92 52 0,000 0,19323475 0,20562707 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,19323475 0,20553617 ! RNA catabolic process GO:0006401 93 53 0,000 0,19656217 0,20898303 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,19656217 0,20889072 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,19656217 0,20879849 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,19656217 0,20870635 ! cell maturation GO:0048469 100 53 0,000 0,19656217 0,20861429 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,19656217 0,20852231 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,19987598 0,2119443 ! cell recognition GO:0008037 85 54 0,000 0,19987598 0,21185093 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,19987598 0,21175764 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,19987598 0,21166444 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,19987598 0,21157132 ! chloride transport GO:0006821 90 55 0,000 0,20317623 0,2149701 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,20317623 0,21487561 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,20317623 0,2147812 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,20317623 0,21468687 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,20317623 0,21459263 ! gastrulation GO:0007369 112 55 0,000 0,20317623 0,21449847 ! heart morphogenesis GO:0003007 97 55 0,000 0,20317623 0,21440439 ! nuclear export GO:0051168 97 55 0,000 0,20317623 0,21431039 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,20317623 0,21421648 ! regulation of actin filament length GO:0030832 105 56 0,000 0,20646297 0,21758647 ! sensory perception of smell GO:0007608 80 56 0,000 0,20646297 0,21749121 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,20646297 0,21739602 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,20646297 0,21730093 ! regulation of DNA replication GO:0006275 101 56 0,000 0,20646297 0,21720591 ! proton transport GO:0015992 94 56 0,000 0,20646297 0,21711098 ! hydrogen transport GO:0006818 97 58 0,000 0,21299618 0,22388327 ! regulation of endocytosis GO:0030100 91 58 0,000 0,21299618 0,2237855 ! adult behavior GO:0030534 99 58 0,000 0,21299618 0,22368782 ! regulation of cellular component size GO:0032535 109 59 0,000 0,21624274 0,22699827 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,21624274 0,22689927 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,21624274 0,22680036 ! establishment of organelle localization GO:0051656 109 59 0,000 0,21624274 0,22670154 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,21947602 0,22999098 ! regulation of heart contraction GO:0008016 110 60 0,000 0,21947602 0,22989086 ! kidney development GO:0001822 122 60 0,000 0,21947602 0,22979082 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,22269607 0,23306078 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,22269607 0,23295945 ! mesoderm development GO:0007498 119 61 0,000 0,22269607 0,23285821 ! tRNA processing GO:0008033 89 61 0,000 0,22269607 0,23275705 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,22269607 0,23265599 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,22590294 0,23590385 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,22590294 0,2358015 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,22909668 0,23903149 ! detection of external stimulus GO:0009581 91 63 0,000 0,22909668 0,23892788 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,22909668 0,23882436 ! cell redox homeostasis GO:0045454 102 64 0,000 0,23227736 0,24203522 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,23227736 0,24193044 ! single fertilization GO:0007338 75 64 0,000 0,23227736 0,24182576 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,23544501 0,24501761 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,23544501 0,24491168 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,23544501 0,24480584 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,23544501 0,24470009 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,23859971 0,24787172 ! actin filament organization GO:0007015 148 66 0,000 0,23859971 0,24776474 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,23859971 0,24765785 ! extracellular matrix organization GO:0030198 133 66 0,000 0,23859971 0,24755105 ! secondary metabolic process GO:0019748 116 66 0,000 0,23859971 0,24744435 ! developmental maturation GO:0021700 116 66 0,000 0,23859971 0,24733774 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,24174149 0,25048666 ! chromosome segregation GO:0007059 113 67 0,000 0,24174149 0,25037883 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,24174149 0,25027109 ! hexose catabolic process GO:0019320 104 67 0,000 0,24174149 0,25016345 ! activation of immune response GO:0002253 105 67 0,000 0,24174149 0,2500559 ! amino acid transport GO:0006865 125 68 0,000 0,24487041 0,25318358 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,24487041 0,25307483 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,24487041 0,25296617 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,24487041 0,2528576 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,24487041 0,25274912 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,24798652 0,25585573 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,24798652 0,25574606 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,24798652 0,25563649 ! urogenital system development GO:0001655 137 69 0,000 0,24798652 0,25552701 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,24798652 0,25541762 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,24798652 0,25530833 ! antigen processing and presentation GO:0019882 104 69 0,000 0,24798652 0,25519913 ! appendage morphogenesis GO:0035107 135 70 0,000 0,25108988 0,25828228 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,25418053 0,26134973 ! appendage development GO:0048736 136 71 0,000 0,25418053 0,26123808 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,25725853 0,26428865 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,25725853 0,26417585 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,26032393 0,26720963 ! fertilization GO:0009566 90 73 0,000 0,26032393 0,26709568 ! exocytosis GO:0006887 133 74 0,000 0,26337678 0,27011276 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,26337678 0,26999767 ! organelle localization GO:0051640 136 74 0,000 0,26337678 0,26988268 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,26641713 0,27288192 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,26944504 0,27586585 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,26944504 0,27574851 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,27246054 0,27871601 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,27246054 0,27859756 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,27246054 0,27847921 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,2754637 0,28142916 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,2754637 0,28130971 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,27845456 0,28424339 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,27845456 0,28412285 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,27845456 0,28400241 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,27845456 0,28388207 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,28143318 0,28679722 ! muscle cell differentiation GO:0042692 159 80 0,000 0,28143318 0,28667579 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,28143318 0,28655448 ! protein import into nucleus GO:0006606 158 80 0,000 0,28143318 0,28643326 ! inorganic anion transport GO:0015698 138 80 0,000 0,28143318 0,28631215 ! digestion GO:0007586 112 81 0,000 0,2843996 0,2892077 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,2843996 0,28908552 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,2843996 0,28896344 ! nuclear import GO:0051170 161 81 0,000 0,2843996 0,28884146 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,28735387 0,29171873 ! response to nutrient GO:0007584 125 82 0,000 0,28735387 0,2915957 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,28735387 0,29147277 ! regulation of lyase activity GO:0051339 160 83 0,000 0,29029604 0,29433302 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,29322616 0,29717866 ! regulation of ligase activity GO:0051340 142 84 0,000 0,29322616 0,29705353 ! response to unfolded protein GO:0006986 131 85 0,000 0,29614428 0,29988348 ! nucleosome assembly GO:0006334 122 85 0,000 0,29614428 0,29975732 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,29614428 0,29963126 ! amine biosynthetic process GO:0009309 138 86 0,000 0,29905045 0,30244447 ! chromatin assembly GO:0031497 124 86 0,000 0,29905045 0,30231739 ! tube morphogenesis GO:0035239 176 86 0,000 0,29905045 0,30219042 ! alcohol catabolic process GO:0046164 130 86 0,000 0,29905045 0,30206355 ! amine transport GO:0015837 155 86 0,000 0,29905045 0,3019368 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,30194472 0,30473112 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,30194472 0,30460335 ! protein localization in nucleus GO:0034504 176 87 0,000 0,30194472 0,30447569 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,30482713 0,30725349 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,31055659 0,31289746 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,31055659 0,31276649 ! response to protein stimulus GO:0051789 149 91 0,000 0,31340372 0,31550182 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,31340372 0,31536987 ! nucleosome organization GO:0034728 138 92 0,000 0,3162392 0,3180901 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,3162392 0,31795717 ! vitamin metabolic process GO:0006766 139 92 0,000 0,3162392 0,31782436 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,31906306 0,32052848 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,31906306 0,3203947 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,31906306 0,32026104 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,32187534 0,32294916 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,32746541 0,32842091 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,32746541 0,32828407 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,33024327 0,33093099 ! hormone metabolic process GO:0042445 157 97 0,000 0,33024327 0,33079322 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,33300975 0,3334255 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,33300975 0,3332868 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,3357649 0,33590451 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,3357649 0,3357649