pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6852-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phospholipid dephosphorylation GO:0046839 12 5 3,000 1,379E-10 3,37E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 4,131E-10 5,046E-07 ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 9,621E-10 7,835E-07 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 1,921E-09 1,173E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 5,000 4,45E-09 2,174E-06 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 5,742E-09 2,338E-06 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 3,000 9,007E-09 3,143E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! endothelial cell migration GO:0043542 31 17 3,000 6,427E-08 1,963E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 3,000 6,427E-08 1,745E-05 ! cardiac muscle tissue development GO:0048738 34 17 3,000 6,427E-08 1,57E-05 ! inositol metabolic process GO:0006020 33 19 3,000 1,043E-07 2,316E-05 ! positive regulation of osteoblast differentiation GO:0045669 52 21 3,000 1,605E-07 3,267E-05 ! regulation of cell-matrix adhesion GO:0001952 81 23 3,000 2,366E-07 4,446E-05 GO:0010810|regulation of cell-substrate adhesion, ! L-serine biosynthetic process GO:0006564 7 6 2,000 2,443E-07 4,263E-05 ! lipid modification GO:0030258 112 60 4,000 3,034E-07 4,941E-05 ! regulation of osteoblast differentiation GO:0045667 68 26 3,000 3,973E-07 6,066E-05 ! ER overload response GO:0006983 13 8 2,000 6,818E-07 9,797E-05 ! negative regulation of protein kinase cascade GO:0010741 72 30 3,000 7,231E-07 9,815E-05 ! BMP signaling pathway GO:0030509 71 32 3,000 9,455E-07 1,216E-04 ! phosphoinositide metabolic process GO:0030384 146 77 4,000 1,064E-06 1,3E-04 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 4,000 1,288E-06 1,498E-04 ! negative regulation of cell adhesion GO:0007162 94 37 3,000 1,721E-06 1,911E-04 ! regulation of protein stability GO:0031647 77 38 3,000 1,92E-06 2,04E-04 ! L-serine metabolic process GO:0006563 21 11 2,000 1,999E-06 2,034E-04 ! establishment or maintenance of cell polarity GO:0007163 96 41 3,000 2,62E-06 2,561E-04 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 3,000 3,182E-06 2,99E-04 ! polyol metabolic process GO:0019751 77 45 3,000 3,828E-06 3,464E-04 ! negative regulation of cell migration GO:0030336 122 46 3,000 4,185E-06 3,652E-04 ! positive regulation of bone mineralization GO:0030501 32 14 2,000 4,387E-06 3,696E-04 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 4,387E-06 3,572E-04 ! G1/S transition checkpoint GO:0031575 37 15 2,000 5,474E-06 4,314E-04 ! positive regulation of biomineral formation GO:0070169 33 15 2,000 5,474E-06 4,179E-04 ! regulation of ossification GO:0030278 123 50 3,000 5,865E-06 4,342E-04 ! response to UV GO:0009411 120 55 3,000 8,609E-06 6,185E-04 ! negative regulation of cell motion GO:0051271 142 55 3,000 8,609E-06 6,009E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 9,768E-06 6,629E-04 ! regulation of bone remodeling GO:0046850 143 57 3,000 9,935E-06 6,56E-04 ! regulation of tissue remodeling GO:0034103 146 58 3,000 1,065E-05 6,848E-04 ! positive regulation of ossification GO:0045778 50 20 2,000 1,36E-05 8,519E-04 ! protein amino acid acetylation GO:0006473 41 20 2,000 1,36E-05 8,306E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 1,578E-05 9,405E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,584E-05 9,214E-04 ! positive regulation of bone remodeling GO:0046852 54 22 2,000 1,831E-05 1,04E-03 GO:0034105|positive regulation of tissue remodeling, ! positive regulation of B cell activation GO:0050871 42 22 2,000 1,831E-05 1,017E-03 ! regulation of bone mineralization GO:0030500 54 23 2,000 2,102E-05 1,141E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,398E-05 1,274E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 2,721E-05 1,414E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,721E-05 1,385E-03 ! regulation of biomineral formation GO:0070167 56 25 2,000 2,721E-05 1,357E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 3,071E-05 1,5E-03 ! negative regulation of cell development GO:0010721 83 26 2,000 3,071E-05 1,471E-03 GO:0050768|negative regulation of neurogenesis, ! insulin receptor signaling pathway GO:0008286 66 27 2,000 3,449E-05 1,62E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 3,856E-05 1,777E-03 ! protein amino acid acylation GO:0043543 59 28 2,000 3,856E-05 1,744E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 4,294E-05 1,907E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 4,763E-05 2,078E-03 ! negative regulation of growth GO:0045926 168 85 3,000 4,846E-05 2,077E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 5,264E-05 2,217E-03 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 1,000 5,363E-05 2,221E-03 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 5,363E-05 2,184E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 5,363E-05 2,148E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 5,363E-05 2,113E-03 ! regulation of leukocyte degranulation GO:0043300 8 5 1,000 5,363E-05 2,08E-03 ! positive regulation of mast cell activation GO:0033005 12 5 1,000 5,363E-05 2,047E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 5,363E-05 2,016E-03 ! mesoderm formation GO:0001707 73 32 2,000 5,799E-05 2,146E-03 ! regulation of cell adhesion GO:0030155 241 92 3,000 6,605E-05 2,408E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 6,889E-05 2,475E-03 ! formation of primary germ layer GO:0001704 76 34 2,000 6,973E-05 2,469E-03 ! serine family amino acid metabolic process GO:0009069 56 34 2,000 6,973E-05 2,433E-03 ! mesoderm morphogenesis GO:0048332 80 35 2,000 7,613E-05 2,62E-03 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 1,000 8,032E-05 2,725E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 8,032E-05 2,688E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 8,032E-05 2,652E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of exocytosis GO:0045921 11 6 1,000 8,032E-05 2,616E-03 ! positive regulation of B cell differentiation GO:0045579 13 6 1,000 8,032E-05 2,582E-03 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 1,000 8,032E-05 2,548E-03 ! regulation of mast cell activation GO:0033003 13 6 1,000 8,032E-05 2,516E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 8,032E-05 2,484E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 9,764E-05 2,982E-03 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 1,056E-04 3,185E-03 ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 1,056E-04 3,146E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of helicase activity GO:0051095 16 7 1,000 1,123E-04 3,305E-03 ! SMAD protein complex assembly GO:0007183 13 7 1,000 1,123E-04 3,265E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,123E-04 3,227E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,123E-04 3,189E-03 ! male sex determination GO:0030238 15 7 1,000 1,123E-04 3,153E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,123E-04 3,117E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,123E-04 3,082E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,123E-04 3,048E-03 ! coenzyme A metabolic process GO:0015936 12 7 1,000 1,123E-04 3,014E-03 ! T cell differentiation GO:0030217 93 42 2,000 1,32E-04 3,504E-03 ! dorsal/ventral pattern formation GO:0009953 75 42 2,000 1,32E-04 3,467E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,495E-04 3,885E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,495E-04 3,844E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,495E-04 3,804E-03 ! response to tumor cell GO:0002347 16 8 1,000 1,495E-04 3,765E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,495E-04 3,726E-03 ! ATP catabolic process GO:0006200 11 8 1,000 1,495E-04 3,689E-03 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 1,495E-04 3,652E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,623E-04 3,926E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,623E-04 3,887E-03 ! activation of adenylate cyclase activity GO:0007190 94 46 2,000 1,733E-04 4,111E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,733E-04 4,072E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,733E-04 4,033E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 1,848E-04 4,26E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,919E-04 4,381E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 1,919E-04 4,341E-03 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 1,919E-04 4,301E-03 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! T cell selection GO:0045058 27 9 1,000 1,919E-04 4,262E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,919E-04 4,223E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 1,919E-04 4,186E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,919E-04 4,149E-03 ! retinal ganglion cell axon guidance GO:0031290 14 9 1,000 1,919E-04 4,112E-03 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 2,000 1,968E-04 4,181E-03 ! positive regulation of DNA binding GO:0043388 83 48 2,000 1,968E-04 4,145E-03 ! positive regulation of cyclase activity GO:0031281 106 49 2,000 2,093E-04 4,371E-03 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,093E-04 4,334E-03 ! positive regulation of lyase activity GO:0051349 107 50 2,000 2,223E-04 4,564E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 2,395E-04 4,876E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,395E-04 4,836E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,395E-04 4,796E-03 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 2,395E-04 4,757E-03 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 2,395E-04 4,719E-03 ! endoderm development GO:0007492 18 10 1,000 2,395E-04 4,681E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 2,395E-04 4,644E-03 ! motor axon guidance GO:0008045 22 10 1,000 2,395E-04 4,607E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 2,395E-04 4,571E-03 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 2,395E-04 4,536E-03 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 2,395E-04 4,501E-03 ! regulation of B cell differentiation GO:0045577 24 10 1,000 2,395E-04 4,466E-03 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 2,395E-04 4,433E-03 ! midbrain development GO:0030901 14 10 1,000 2,395E-04 4,399E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 2,395E-04 4,366E-03 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of binding GO:0051099 88 52 2,000 2,498E-04 4,521E-03 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 2,498E-04 4,488E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,644E-04 4,714E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 2,000 2,644E-04 4,68E-03 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 2,923E-04 5,137E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,923E-04 5,1E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 2,923E-04 5,064E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,923E-04 5,028E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,923E-04 4,993E-03 ! alpha-beta T cell activation GO:0046631 26 11 1,000 2,923E-04 4,959E-03 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 2,923E-04 4,924E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 2,923E-04 4,891E-03 ! regulation of DNA replication GO:0006275 105 56 2,000 3,112E-04 5,173E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 3,453E-04 5,7E-03 ! gastrulation GO:0007369 122 58 2,000 3,453E-04 5,662E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 3,502E-04 5,704E-03 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 3,502E-04 5,666E-03 ! virus-host interaction GO:0019048 30 12 1,000 3,502E-04 5,629E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 3,502E-04 5,592E-03 ! ventral spinal cord development GO:0021517 25 12 1,000 3,502E-04 5,555E-03 ! histone acetylation GO:0016573 27 12 1,000 3,502E-04 5,52E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,502E-04 5,484E-03 ! localization within membrane GO:0051668 26 12 1,000 3,502E-04 5,449E-03 ! cGMP metabolic process GO:0046068 18 13 1,000 4,132E-04 6,39E-03 GO:0006182|cGMP biosynthetic process, ! cartilage condensation GO:0001502 22 13 1,000 4,132E-04 6,349E-03 ! ribonucleotide catabolic process GO:0009261 21 13 1,000 4,132E-04 6,31E-03 ! response to X-ray GO:0010165 28 13 1,000 4,132E-04 6,271E-03 ! monoamine transport GO:0015844 21 13 1,000 4,132E-04 6,232E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 4,132E-04 6,194E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 4,132E-04 6,156E-03 ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 4,132E-04 6,119E-03 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 4,132E-04 6,082E-03 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 1,000 4,132E-04 6,045E-03 ! mesoderm development GO:0007498 128 63 2,000 4,407E-04 6,408E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 4,616E-04 6,672E-03 ! retina development in camera-type eye GO:0060041 28 14 1,000 4,814E-04 6,918E-03 ! palate development GO:0060021 32 14 1,000 4,814E-04 6,877E-03 ! regulation of cellular pH GO:0030641 27 14 1,000 4,814E-04 6,837E-03 ! response to gamma radiation GO:0010332 30 14 1,000 4,814E-04 6,798E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 4,814E-04 6,759E-03 ! regulation of calcium-mediated signaling GO:0050848 29 14 1,000 4,814E-04 6,72E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 4,831E-04 6,706E-03 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 5,052E-04 6,974E-03 ! negative regulation of cell growth GO:0030308 142 67 2,000 5,28E-04 7,247E-03 ! activation of MAPK activity GO:0000187 124 67 2,000 5,28E-04 7,207E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 5,546E-04 7,527E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 5,546E-04 7,486E-03 ! regulation of exocytosis GO:0017157 26 15 1,000 5,546E-04 7,445E-03 ! positive regulation of axonogenesis GO:0050772 33 15 1,000 5,546E-04 7,404E-03 ! negative regulation of cell size GO:0045792 144 69 2,000 5,756E-04 7,642E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 5,756E-04 7,601E-03 ! lung development GO:0030324 165 69 2,000 5,756E-04 7,56E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 5,756E-04 7,52E-03 ! negative regulation of kinase activity GO:0033673 145 70 2,000 6,003E-04 7,801E-03 ! cell cycle checkpoint GO:0000075 145 71 2,000 6,258E-04 8,089E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,329E-04 8,137E-03 ! stem cell development GO:0048864 46 16 1,000 6,329E-04 8,095E-03 GO:0019827|stem cell maintenance, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,329E-04 8,053E-03 ! appendage morphogenesis GO:0035107 150 72 2,000 6,519E-04 8,252E-03 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 2,000 6,519E-04 8,209E-03 ! appendage development GO:0048736 151 73 2,000 6,787E-04 8,503E-03 GO:0060173|limb development, ! negative regulation of transferase activity GO:0051348 155 74 2,000 7,062E-04 8,802E-03 ! respiratory system development GO:0060541 175 74 2,000 7,062E-04 8,757E-03 ! activation of MAPKK activity GO:0000186 43 17 1,000 7,162E-04 8,836E-03 ! neutrophil chemotaxis GO:0030593 29 17 1,000 7,162E-04 8,792E-03 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 7,162E-04 8,748E-03 ! axon guidance GO:0007411 162 75 2,000 7,344E-04 8,926E-03 ! lymphocyte differentiation GO:0030098 193 76 2,000 7,633E-04 9,231E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 8,045E-04 9,681E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 8,045E-04 9,634E-03 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 8,232E-04 9,81E-03 ! protein oligomerization GO:0051259 149 79 2,000 8,543E-04 0,01013108 ! cell differentiation in spinal cord GO:0021515 37 19 1,000 8,978E-04 0,01059523 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 9,186E-04 0,01078927 ! protein import into nucleus GO:0006606 174 82 2,000 9,519E-04 0,01112672 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 9,859E-04 0,01146975 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 9,859E-04 0,01141539 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 2,000 9,859E-04 0,01136155 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 9,96E-04 0,01142352 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 9,96E-04 0,01137014 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 9,96E-04 0,01131726 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 9,96E-04 0,01126486 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 9,96E-04 0,01121295 ! purine nucleotide catabolic process GO:0006195 32 20 1,000 9,96E-04 0,01116152 ! negative regulation of translation GO:0017148 32 20 1,000 9,96E-04 0,01111055 ! T cell activation GO:0042110 189 84 2,000 1,021E-03 0,01133487 ! regulation of cyclase activity GO:0031279 168 85 2,000 1,056E-03 0,0116768 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,056E-03 0,0116242 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 1,093E-03 0,01197025 ! regulation of lyase activity GO:0051339 169 86 2,000 1,093E-03 0,01191681 ! positive regulation of cell activation GO:0050867 161 86 2,000 1,093E-03 0,01186385 GO:0002696|positive regulation of leukocyte activation, ! lipid phosphorylation GO:0046834 43 21 1,000 1,099E-03 0,0118817 ! ovarian follicle development GO:0001541 39 21 1,000 1,099E-03 0,01182936 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 1,099E-03 0,01177748 ! leukotriene biosynthetic process GO:0019370 42 21 1,000 1,099E-03 0,01172605 GO:0043450|alkene biosynthetic process, ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,099E-03 0,01167506 ! amine biosynthetic process GO:0009309 146 88 2,000 1,168E-03 0,01234933 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,206E-03 0,01270373 ! regulation of DNA binding GO:0051101 167 89 2,000 1,206E-03 0,0126492 ! protein localization in nucleus GO:0034504 192 89 2,000 1,206E-03 0,01259515 ! hindlimb morphogenesis GO:0035137 47 22 1,000 1,207E-03 0,01255029 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,207E-03 0,01249711 ! cellular response to starvation GO:0009267 37 22 1,000 1,207E-03 0,01244438 ! ureteric bud development GO:0001657 50 22 1,000 1,207E-03 0,01239209 ! cell aging GO:0007569 48 22 1,000 1,207E-03 0,01234024 ! stem cell differentiation GO:0048863 57 22 1,000 1,207E-03 0,01228882 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 1,207E-03 0,01223783 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,207E-03 0,01218726 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,207E-03 0,01213711 ! activation of JUN kinase activity GO:0007257 47 22 1,000 1,207E-03 0,01208737 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 1,286E-03 0,01282564 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 2,000 1,286E-03 0,01277351 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,32E-03 0,01305795 ! axis specification GO:0009798 43 23 1,000 1,32E-03 0,0130053 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 1,32E-03 0,01295307 ! bone development GO:0060348 206 92 2,000 1,327E-03 0,01297105 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,438E-03 0,0139968 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 1,438E-03 0,01394126 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 1,438E-03 0,01388616 GO:0042278|purine nucleoside metabolic process, ! sex determination GO:0007530 48 24 1,000 1,438E-03 0,01383149 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,438E-03 0,01377725 ! leukotriene metabolic process GO:0006691 47 24 1,000 1,438E-03 0,01372343 ! oogenesis GO:0048477 44 24 1,000 1,438E-03 0,01367003 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,438E-03 0,01361704 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 1,456E-03 0,01373078 ! sex differentiation GO:0007548 171 96 2,000 1,5E-03 0,01409556 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 1,545E-03 0,01446544 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,561E-03 0,0145531 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,561E-03 0,01449777 ! leukocyte adhesion GO:0007159 55 25 1,000 1,561E-03 0,01444285 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,561E-03 0,01438835 ! negative regulation of DNA replication GO:0008156 45 25 1,000 1,561E-03 0,01433426 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 1,561E-03 0,01428057 ! interaction with host GO:0051701 66 25 1,000 1,561E-03 0,01422729 ! cellular alkene metabolic process GO:0043449 48 25 1,000 1,561E-03 0,0141744 ! leukocyte differentiation GO:0002521 232 98 2,000 1,592E-03 0,01440069 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 1,592E-03 0,01434755 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 1,592E-03 0,01429481 ! spinal cord development GO:0021510 54 26 1,000 1,688E-03 0,01510771 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,688E-03 0,01505257 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,688E-03 0,01499783 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 1,000 1,688E-03 0,01494349 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 1,688E-03 0,01488955 ! embryonic pattern specification GO:0009880 49 27 1,000 1,821E-03 0,01599862 ! positive regulation of cell projection organization GO:0031346 66 27 1,000 1,821E-03 0,01594128 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 1,821E-03 0,01588434 ! mitochondrial membrane organization GO:0007006 60 27 1,000 1,821E-03 0,01582782 ! response to starvation GO:0042594 47 27 1,000 1,821E-03 0,01577169 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,821E-03 0,01571596 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,958E-03 0,01683977 ! base-excision repair GO:0006284 41 28 1,000 1,958E-03 0,01678068 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 1,000 1,958E-03 0,01672201 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 1,958E-03 0,01666374 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,958E-03 0,01660588 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 1,958E-03 0,01654842 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 1,958E-03 0,01649136 ! somitogenesis GO:0001756 52 29 1,000 2,099E-03 0,01762537 ! icosanoid biosynthetic process GO:0046456 60 30 1,000 2,246E-03 0,01879119 ! immune response-activating signal transduction GO:0002757 58 30 1,000 2,246E-03 0,01872706 GO:0002764|immune response-regulating signal transduction, ! ovulation cycle process GO:0022602 55 31 1,000 2,397E-03 0,01992032 ! positive regulation of immune effector process GO:0002699 78 31 1,000 2,397E-03 0,0198528 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 2,553E-03 0,02107287 ! metanephros development GO:0001656 81 32 1,000 2,553E-03 0,02100192 ! ovulation cycle GO:0042698 57 32 1,000 2,553E-03 0,02093144 ! hindbrain development GO:0030902 65 32 1,000 2,553E-03 0,02086144 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 2,553E-03 0,0207919 ! positive regulation of catabolic process GO:0009896 72 32 1,000 2,553E-03 0,02072282 ! regulation of pH GO:0006885 56 33 1,000 2,714E-03 0,0219535 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 2,714E-03 0,02188104 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 1,000 2,714E-03 0,02180907 ! response to ionizing radiation GO:0010212 74 33 1,000 2,714E-03 0,02173756 ! regulation of axonogenesis GO:0050770 86 33 1,000 2,714E-03 0,02166652 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 2,714E-03 0,02159595 ! leukocyte chemotaxis GO:0030595 55 33 1,000 2,714E-03 0,02152583 GO:0060326|cell chemotaxis, ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 2,879E-03 0,02276273 ! DNA damage checkpoint GO:0000077 78 35 1,000 3,049E-03 0,02402804 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 3,049E-03 0,02395078 ! calcium-mediated signaling GO:0019722 67 35 1,000 3,049E-03 0,02387402 ! positive regulation of cell development GO:0010720 85 36 1,000 3,223E-03 0,02515954 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 3,223E-03 0,02507942 ! odontogenesis GO:0042476 74 37 1,000 3,403E-03 0,02638844 ! female gonad development GO:0008585 71 37 1,000 3,403E-03 0,02630493 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 3,586E-03 0,02763692 ! DNA integrity checkpoint GO:0031570 82 38 1,000 3,586E-03 0,02755001 ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 3,586E-03 0,02746365 ! glycogen metabolic process GO:0005977 63 38 1,000 3,586E-03 0,02737783 ! regulation of neuron projection development GO:0010975 102 39 1,000 3,774E-03 0,02872437 ! carbohydrate homeostasis GO:0033500 59 39 1,000 3,774E-03 0,02863516 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 1,000 3,774E-03 0,02854651 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 3,774E-03 0,0284584 ! glucan metabolic process GO:0044042 64 39 1,000 3,774E-03 0,02837084 GO:0006073|cellular glucan metabolic process, ! development of primary female sexual characteristics GO:0046545 80 40 1,000 3,967E-03 0,02972749 GO:0046660|female sex differentiation, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 4,164E-03 0,03110937 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 4,366E-03 0,0325161 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 4,366E-03 0,03241727 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 4,366E-03 0,03231904 ! regulation of T cell differentiation GO:0045580 78 42 1,000 4,366E-03 0,03222139 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 4,572E-03 0,03364054 GO:0090047|positive regulation of transcription regulator activity, ! regulation of T cell proliferation GO:0042129 80 43 1,000 4,572E-03 0,03353952 ! segmentation GO:0035282 78 43 1,000 4,572E-03 0,0334391 ! energy reserve metabolic process GO:0006112 76 44 1,000 4,782E-03 0,03487418 ! double-strand break repair GO:0006302 85 44 1,000 4,782E-03 0,03477038 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 4,997E-03 0,03622491 ! B cell differentiation GO:0030183 124 45 1,000 4,997E-03 0,03611774 ! female gamete generation GO:0007292 71 45 1,000 4,997E-03 0,03601119 ! developmental growth GO:0048589 88 45 1,000 4,997E-03 0,03590528 ! glycolysis GO:0006096 71 46 1,000 5,216E-03 0,03737081 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 5,216E-03 0,03726154 ! leukocyte migration GO:0050900 75 46 1,000 5,216E-03 0,0371529 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 5,216E-03 0,0370449 ! positive regulation of protein transport GO:0051222 80 46 1,000 5,216E-03 0,03693753 ! regulation of JNK cascade GO:0046328 104 47 1,000 5,44E-03 0,03840969 ! positive regulation of cell cycle GO:0045787 96 48 1,000 5,668E-03 0,03990392 ! mitochondrial transport GO:0006839 94 48 1,000 5,668E-03 0,03978925 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 5,668E-03 0,03967524 ! male sex differentiation GO:0046661 93 48 1,000 5,668E-03 0,03956188 ! icosanoid metabolic process GO:0006690 92 48 1,000 5,668E-03 0,03944917 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 5,9E-03 0,0409492 ! JNK cascade GO:0007254 106 49 1,000 5,9E-03 0,0408332 ! activation of caspase activity GO:0006919 95 50 1,000 6,137E-03 0,0423505 ! regulation of cell projection organization GO:0031344 135 51 1,000 6,378E-03 0,04388869 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 6,378E-03 0,04376541 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 6,623E-03 0,04532015 ! histone modification GO:0016570 104 52 1,000 6,623E-03 0,04519356 ! positive regulation of growth GO:0045927 96 53 1,000 6,872E-03 0,04676448 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 6,872E-03 0,04663458 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 6,872E-03 0,0465054 ! activation of phospholipase C activity GO:0007202 110 54 1,000 7,126E-03 0,04808812 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 7,126E-03 0,04795565 ! covalent chromatin modification GO:0016569 115 54 1,000 7,126E-03 0,0478239 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 7,383E-03 0,04941808 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 7,383E-03 0,04928306 ! glucose catabolic process GO:0006007 88 56 1,000 7,645E-03 0,05089236 ! positive regulation of caspase activity GO:0043280 108 57 1,000 7,911E-03 0,05252049 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 7,911E-03 0,05237816 ! heart morphogenesis GO:0003007 105 57 1,000 7,911E-03 0,0522366 ! nucleotide-excision repair GO:0006289 91 57 1,000 7,911E-03 0,0520958 ! regulation of intracellular transport GO:0032386 108 57 1,000 7,911E-03 0,05195576 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 8,182E-03 0,05358628 ! aging GO:0007568 112 58 1,000 8,182E-03 0,053443 ! positive regulation of lipase activity GO:0060193 115 58 1,000 8,182E-03 0,05330049 ! heterocycle catabolic process GO:0046700 100 60 1,000 8,734E-03 0,05675016 ! kidney development GO:0001822 133 60 1,000 8,734E-03 0,05659963 ! positive regulation of secretion GO:0051047 110 61 1,000 9,017E-03 0,05827566 ! camera-type eye development GO:0043010 126 61 1,000 9,017E-03 0,0581219 ! viral reproductive process GO:0022415 132 62 1,000 9,303E-03 0,05981116 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 9,303E-03 0,05965417 ! nucleoside metabolic process GO:0009116 91 62 1,000 9,303E-03 0,05949801 ! skeletal system morphogenesis GO:0048705 118 63 1,000 9,594E-03 0,06119616 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 9,889E-03 0,062911 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,01018718 0,06464227 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,01018718 0,0644748 ! gonad development GO:0008406 115 66 1,000 0,01048974 0,06621816 ! fatty acid biosynthetic process GO:0006633 139 67 1,000 0,01079625 0,06797743 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,0111067 0,06975235 ! hexose catabolic process GO:0019320 113 68 1,000 0,0111067 0,0695735 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,0111067 0,06939556 ! viral reproduction GO:0016032 142 68 1,000 0,0111067 0,06921853 ! regulation of lipase activity GO:0060191 137 68 1,000 0,0111067 0,0690424 ! urogenital system development GO:0001655 149 69 1,000 0,01142106 0,07081637 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01162192 0,07187936 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01162192 0,07169785 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01162192 0,07151725 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01162192 0,07133756 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01162192 0,07115877 ! neuron fate determination GO:0048664 7 5 0,000 0,01162192 0,07098087 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01162192 0,07080386 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01162192 0,07062773 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01162192 0,07045248 ! polyol transport GO:0015791 12 5 0,000 0,01162192 0,07027809 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01162192 0,07010456 ! response to superoxide GO:0000303 10 5 0,000 0,01162192 0,06993189 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01162192 0,06976007 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01162192 0,06958909 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,01162192 0,06941895 ! female meiosis GO:0007143 10 5 0,000 0,01162192 0,06924963 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01162192 0,06908114 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01162192 0,06891347 ! hypothalamus development GO:0021854 9 5 0,000 0,01162192 0,06874661 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01162192 0,06858055 ! cobalt ion transport GO:0006824 11 5 0,000 0,01162192 0,0684153 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01162192 0,06825084 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01162192 0,06808717 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01162192 0,06792428 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01162192 0,06776217 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01162192 0,06760083 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01162192 0,06744026 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01162192 0,06728045 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01162192 0,06712139 ! transposition GO:0032196 9 5 0,000 0,01162192 0,06696309 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01162192 0,06680553 ! negative chemotaxis GO:0050919 16 5 0,000 0,01162192 0,06664871 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01162192 0,06649262 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01162192 0,06633726 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01162192 0,06618263 ! behavioral response to pain GO:0048266 10 5 0,000 0,01162192 0,06602872 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01162192 0,06587552 ! Notch receptor processing GO:0007220 11 5 0,000 0,01162192 0,06572303 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01162192 0,06557124 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01162192 0,06542016 ! micturition GO:0060073 9 5 0,000 0,01162192 0,06526977 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01162192 0,06512007 ! copulation GO:0007620 9 5 0,000 0,01162192 0,06497105 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01162192 0,06482271 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01162192 0,06467505 ! bioluminescence GO:0008218 9 5 0,000 0,01162192 0,06452806 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01162192 0,06438174 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01162192 0,06423608 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01162192 0,06409108 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01162192 0,06394673 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01162192 0,06380303 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01162192 0,06365997 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01162192 0,06351756 ! grooming behavior GO:0007625 6 5 0,000 0,01162192 0,06337578 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01162192 0,06323463 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01162192 0,06309411 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01162192 0,06295421 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01162192 0,06281493 ! response to protozoan GO:0001562 13 5 0,000 0,01162192 0,06267627 ! lymph vessel development GO:0001945 10 5 0,000 0,01162192 0,06253821 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01162192 0,06240077 ! endochondral ossification GO:0001958 17 5 0,000 0,01162192 0,06226392 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01162192 0,06212768 ! single strand break repair GO:0000012 8 5 0,000 0,01162192 0,06199203 ! parathyroid gland development GO:0060017 14 5 0,000 0,01162192 0,06185697 ! anagen GO:0042640 7 5 0,000 0,01162192 0,0617225 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01162192 0,06158861 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01162192 0,0614553 ! cytokine secretion GO:0050663 15 5 0,000 0,01162192 0,06132257 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01162192 0,06119041 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01162192 0,06105881 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01162192 0,06092779 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01162192 0,06079732 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01162192 0,06066741 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01162192 0,06053806 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01162192 0,06040925 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01162192 0,06028099 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01162192 0,06015328 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01162192 0,06002611 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01162192 0,05989947 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01162192 0,05977337 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01162192 0,05964779 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01162192 0,05952274 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01162192 0,05939822 ! microvillus organization GO:0032528 8 5 0,000 0,01162192 0,05927421 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01162192 0,05915073 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01162192 0,05902775 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01162192 0,05890529 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01162192 0,05878333 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01162192 0,05866188 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01162192 0,05854092 ! polyol catabolic process GO:0046174 9 5 0,000 0,01162192 0,05842047 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01162192 0,05830051 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01162192 0,05818104 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01162192 0,05806206 ! muscle cell migration GO:0014812 8 5 0,000 0,01162192 0,05794357 ! mitochondrial fission GO:0000266 8 5 0,000 0,01162192 0,05782556 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01162192 0,05770803 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01162192 0,05759097 ! mRNA transcription GO:0009299 10 5 0,000 0,01162192 0,05747439 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01162192 0,05735828 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01162192 0,05724264 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01162192 0,05712746 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01162192 0,05701275 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01162192 0,05689849 ! monocyte activation GO:0042117 10 5 0,000 0,01162192 0,0567847 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01162192 0,05667135 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01162192 0,05655846 ! response to food GO:0032094 6 5 0,000 0,01162192 0,05644602 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01162192 0,05633402 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01162192 0,05622247 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01162192 0,05611136 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01162192 0,05600069 ! forebrain neuron development GO:0021884 13 5 0,000 0,01162192 0,05589045 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01162192 0,05578065 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01162192 0,05567127 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01162192 0,05556233 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01162192 0,05545381 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01162192 0,05534571 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01162192 0,05523803 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01162192 0,05513077 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01162192 0,05502393 ! lipid glycosylation GO:0030259 7 5 0,000 0,01162192 0,0549175 ! nucleobase transport GO:0015851 6 5 0,000 0,01162192 0,05481148 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01162192 0,05470587 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01162192 0,05460067 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01162192 0,05449587 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01162192 0,05439147 ! basic amino acid transport GO:0015802 12 5 0,000 0,01162192 0,05428747 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01162192 0,05418387 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01162192 0,05408066 ! actin nucleation GO:0045010 11 5 0,000 0,01162192 0,05397785 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01162192 0,05387542 ! depurination GO:0045007 5 5 0,000 0,01162192 0,05377339 ! depyrimidination GO:0045008 10 5 0,000 0,01162192 0,05367174 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01162192 0,05357047 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01162192 0,05346958 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01162192 0,05336908 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01162192 0,05326895 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01162192 0,05316919 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01162192 0,05306981 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01162192 0,0529708 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01162192 0,05287216 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01162192 0,05277388 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01162192 0,05267597 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01162192 0,05257842 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01162192 0,05248124 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01162192 0,05238441 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01162192 0,05228793 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01162192 0,05219182 ! response to arsenic GO:0046685 11 5 0,000 0,01162192 0,05209605 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01162192 0,05200064 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01162192 0,05190557 GO:0002448|mast cell mediated immunity, ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01162192 0,05181086 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01162192 0,05171648 ! response to mercury ion GO:0046689 8 5 0,000 0,01162192 0,05162245 ! response to cadmium ion GO:0046686 7 5 0,000 0,01162192 0,05152876 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01162192 0,05143541 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01162192 0,0513424 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01162192 0,05124973 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01162192 0,05115738 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01162192 0,05106538 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01162192 0,0509737 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01162192 0,05088235 ! decidualization GO:0046697 11 5 0,000 0,01162192 0,05079132 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01162192 0,05070062 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01162192 0,05061025 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01162192 0,05052019 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01162192 0,05043046 ! embryonic cleavage GO:0040016 6 5 0,000 0,01162192 0,05034104 ! peroxisome fission GO:0016559 5 5 0,000 0,01162192 0,05025194 ! histone demethylation GO:0016577 13 5 0,000 0,01162192 0,05016316 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01162192 0,05007469 ! mitotic recombination GO:0006312 9 5 0,000 0,01162192 0,04998653 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01162192 0,04989868 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01162192 0,04981114 ! metaphase plate congression GO:0051310 7 5 0,000 0,01162192 0,0497239 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01162192 0,04963697 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01162192 0,04955035 ! enteric nervous system development GO:0048484 8 5 0,000 0,01162192 0,04946402 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01162192 0,049378 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01162192 0,04929227 GO:0031295|T cell costimulation, ! muscle cell proliferation GO:0033002 12 5 0,000 0,01162192 0,04920684 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01162192 0,04912171 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01162192 0,04903687 ! B cell homeostasis GO:0001782 13 5 0,000 0,01162192 0,04895233 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01162192 0,04886807 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01162192 0,0487841 ! metaphase GO:0051323 11 5 0,000 0,01162192 0,04870043 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01162192 0,04861704 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01162192 0,04853393 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01162192 0,04845111 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01162192 0,04836857 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01162192 0,04828631 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01162192 0,04820433 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01162192 0,04812262 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01162192 0,0480412 ! response to redox state GO:0051775 6 5 0,000 0,01162192 0,04796005 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01162192 0,04787917 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01162192 0,04779857 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01162192 0,04771823 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01162192 0,04763817 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01162192 0,04755837 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01162192 0,04747884 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01162192 0,04739958 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01162192 0,04732058 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01162192 0,04724184 ! striatum development GO:0021756 14 5 0,000 0,01162192 0,04716337 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01162192 0,04708516 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01162192 0,0470072 ! glial cell migration GO:0008347 10 5 0,000 0,01162192 0,0469295 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01162192 0,04685206 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01162192 0,04677487 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01162192 0,04669794 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01162192 0,04662126 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01162192 0,04654483 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01162192 0,04646866 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01162192 0,04639273 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01162192 0,04631704 ! neuroprotection GO:0043526 8 5 0,000 0,01162192 0,04624161 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01162192 0,04616642 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01162192 0,04609147 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01162192 0,04601677 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01162192 0,04594231 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01162192 0,04586809 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01162192 0,04579411 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01162192 0,04572037 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01162192 0,04564686 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01162192 0,04557359 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01162192 0,04550056 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01162192 0,04542776 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01162192 0,04535519 ! spindle assembly GO:0051225 6 5 0,000 0,01162192 0,04528285 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01162192 0,04521075 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01162192 0,04513887 ! protein palmitoylation GO:0018345 12 5 0,000 0,01162192 0,04506722 ! drug metabolic process GO:0017144 7 5 0,000 0,01162192 0,0449958 ! stem cell division GO:0017145 11 5 0,000 0,01162192 0,0449246 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01162192 0,04485363 ! organ regeneration GO:0031100 7 5 0,000 0,01162192 0,04478288 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01162192 0,04471236 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01162192 0,04464206 ! activation of immune response GO:0002253 120 70 1,000 0,01173932 0,04502221 ! actin filament organization GO:0007015 167 72 1,000 0,01238743 0,04743339 ! B cell activation GO:0042113 179 72 1,000 0,01238743 0,04735916 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01238743 0,04728516 ! regulation of immune effector process GO:0002697 156 73 1,000 0,01271726 0,04846843 ! regulation of caspase activity GO:0043281 136 74 1,000 0,0130509 0,04966254 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,0130509 0,0495853 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01338834 0,05078837 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,01338834 0,05070963 ! eye development GO:0001654 155 75 1,000 0,01338834 0,05063113 ! rhythmic process GO:0048511 142 75 1,000 0,01338834 0,05055288 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01393024 0,05251786 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01393024 0,05243694 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01393024 0,05235627 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01393024 0,05227584 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01393024 0,05219567 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01393024 0,05211573 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01393024 0,05203605 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01393024 0,0519566 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01393024 0,0518774 ! response to oxygen radical GO:0000305 11 6 0,000 0,01393024 0,05179844 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01393024 0,05171972 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01393024 0,05164124 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01393024 0,05156299 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01393024 0,05148498 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01393024 0,05140721 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01393024 0,05132967 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01393024 0,05125237 ! forebrain regionalization GO:0021871 9 6 0,000 0,01393024 0,0511753 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01393024 0,05109846 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01393024 0,05102185 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01393024 0,05094547 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01393024 0,05086932 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01393024 0,05079339 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01393024 0,0507177 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01393024 0,05064222 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01393024 0,05056697 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01393024 0,05049195 ! malate metabolic process GO:0006108 13 6 0,000 0,01393024 0,05041715 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01393024 0,05034257 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01393024 0,0502682 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01393024 0,05019406 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01393024 0,05012014 ! protein refolding GO:0042026 15 6 0,000 0,01393024 0,05004643 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01393024 0,04997294 ! opsonization GO:0008228 8 6 0,000 0,01393024 0,04989967 ! mating behavior GO:0007617 7 6 0,000 0,01393024 0,04982661 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01393024 0,04975376 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01393024 0,04968113 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01393024 0,04960871 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01393024 0,0495365 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01393024 0,0494645 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01393024 0,04939271 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01393024 0,04932112 ! toxin metabolic process GO:0009404 11 6 0,000 0,01393024 0,04924975 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01393024 0,04917858 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01393024 0,04910761 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01393024 0,04903685 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01393024 0,04896629 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01393024 0,04889594 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01393024 0,04882579 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01393024 0,04875584 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01393024 0,04868609 ! thymic T cell selection GO:0045061 16 6 0,000 0,01393024 0,04861653 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01393024 0,04854718 ! protein lipoylation GO:0009249 10 6 0,000 0,01393024 0,04847803 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01393024 0,04840907 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01393024 0,0483403 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01393024 0,04827174 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01393024 0,04820336 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01393024 0,04813518 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01393024 0,04806719 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01393024 0,0479994 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01393024 0,04793179 ! hyperosmotic response GO:0006972 10 6 0,000 0,01393024 0,04786438 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01393024 0,04779715 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01393024 0,04773012 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01393024 0,04766327 ! urea metabolic process GO:0019627 7 6 0,000 0,01393024 0,04759661 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01393024 0,04753013 ! neutrophil activation GO:0042119 7 6 0,000 0,01393024 0,04746384 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01393024 0,04739774 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01393024 0,04733181 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01393024 0,04726608 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01393024 0,04720052 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01393024 0,04713514 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01393024 0,04706995 ! neuron apoptosis GO:0051402 15 6 0,000 0,01393024 0,04700494 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01393024 0,0469401 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01393024 0,04687545 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01393024 0,04681097 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01393024 0,04674667 ! carnitine transport GO:0015879 10 6 0,000 0,01393024 0,04668254 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01393024 0,04661859 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01393024 0,04655482 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01393024 0,04649122 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01393024 0,0464278 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01393024 0,04636454 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01393024 0,04630146 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01393024 0,04623855 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01393024 0,04617581 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01393024 0,04611324 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01393024 0,04605084 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01393024 0,04598861 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01393024 0,04592655 ! response to UV-C GO:0010225 14 6 0,000 0,01393024 0,04586466 ! astrocyte development GO:0014002 16 6 0,000 0,01393024 0,04580293 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01393024 0,04574136 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01393024 0,04567997 ! interaction with symbiont GO:0051702 14 6 0,000 0,01393024 0,04561873 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01393024 0,04555766 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01393024 0,04549676 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01393024 0,04543601 ! response to copper ion GO:0046688 10 6 0,000 0,01393024 0,04537543 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01393024 0,04531501 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01393024 0,04525475 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01393024 0,04519465 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01393024 0,04513471 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01393024 0,04507493 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01393024 0,04501531 ! hair follicle maturation GO:0048820 8 6 0,000 0,01393024 0,04495584 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01393024 0,04489654 ! Schwann cell development GO:0014044 15 6 0,000 0,01393024 0,04483738 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01393024 0,04477839 ! response to pheromone GO:0019236 6 6 0,000 0,01393024 0,04471955 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01393024 0,04466086 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01393024 0,04460233 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01393024 0,04454395 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01393024 0,04448572 ! subpallium development GO:0021544 15 6 0,000 0,01393024 0,04442764 ! neural tube patterning GO:0021532 8 6 0,000 0,01393024 0,04436972 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01393024 0,04431195 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01393024 0,04425432 ! G2 phase GO:0051319 16 6 0,000 0,01393024 0,04419685 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01393024 0,04413953 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01393024 0,04408235 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01393024 0,04402532 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01393024 0,04396844 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01393024 0,04391171 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01393024 0,04385512 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01393024 0,04379868 ! receptor internalization GO:0031623 11 6 0,000 0,01393024 0,04374238 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01393024 0,04368623 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01393024 0,04363022 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01393024 0,04357436 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01393024 0,04351864 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01393024 0,04346306 ! protein deubiquitination GO:0016579 16 6 0,000 0,01393024 0,04340762 ! protein destabilization GO:0031648 9 6 0,000 0,01393024 0,04335232 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01393024 0,04329717 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01393024 0,04324215 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01393024 0,04318728 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01393024 0,04313254 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01393024 0,04307794 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01393024 0,04302348 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01393024 0,04296916 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01393024 0,04291497 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01393024 0,04286092 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01393024 0,04280701 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01393024 0,04275323 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01393024 0,04269959 ! neural plate development GO:0001840 9 6 0,000 0,01393024 0,04264608 ! catecholamine transport GO:0051937 9 6 0,000 0,01393024 0,04259271 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01393024 0,04253947 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01393024 0,04248636 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01393024 0,04243338 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01393024 0,04238054 ! maternal placenta development GO:0001893 12 6 0,000 0,01393024 0,04232783 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01393024 0,04227525 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01393024 0,0422228 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01393024 0,04217048 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01393024 0,04211828 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01393024 0,04206622 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01393024 0,04201429 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01393024 0,04196248 GO:0055081|anion homeostasis, ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01407453 0,04234494 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,01407453 0,04229285 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,01407453 0,04224089 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01407453 0,04218906 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,01513184 0,0453028 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,01513184 0,04524735 ! response to hypoxia GO:0001666 178 81 1,000 0,01549167 0,04626668 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01585516 0,04729445 ! response to drug GO:0042493 149 83 1,000 0,0162223 0,04833059 ! response to oxygen levels GO:0070482 183 83 1,000 0,0162223 0,04827172 ! tRNA transcription GO:0009304 17 7 0,000 0,01623323 0,04824548 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01623323 0,04818686 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01623323 0,04812838 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01623323 0,04807005 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01623323 0,04801185 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01623323 0,04795379 ! sleep GO:0030431 16 7 0,000 0,01623323 0,04789588 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01623323 0,0478381 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01623323 0,04778047 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01623323 0,04772297 ! prostate gland development GO:0030850 14 7 0,000 0,01623323 0,04766561 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01623323 0,04760839 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01623323 0,0475513 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01623323 0,04749436 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01623323 0,04743755 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01623323 0,04738087 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01623323 0,04732433 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01623323 0,04726792 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01623323 0,04721165 ! glycolipid transport GO:0046836 11 7 0,000 0,01623323 0,04715551 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01623323 0,04709951 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01623323 0,04704364 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01623323 0,0469879 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01623323 0,04693229 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01623323 0,04687682 ! mRNA stabilization GO:0048255 18 7 0,000 0,01623323 0,04682147 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01623323 0,04676626 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01623323 0,04671118 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01623323 0,04665622 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01623323 0,0466014 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01623323 0,0465467 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01623323 0,04649213 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01623323 0,04643769 ! lipoprotein transport GO:0042953 14 7 0,000 0,01623323 0,04638338 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01623323 0,04632919 ! rhythmic behavior GO:0007622 17 7 0,000 0,01623323 0,04627513 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01623323 0,0462212 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01623323 0,04616739 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01623323 0,04611371 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01623323 0,04606015 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01623323 0,04600671 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01623323 0,0459534 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01623323 0,04590022 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01623323 0,04584715 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01623323 0,04579421 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01623323 0,04574139 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01623323 0,0456887 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01623323 0,04563612 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01623323 0,04558366 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01623323 0,04553133 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01623323 0,04547911 ! spinal cord patterning GO:0021511 14 7 0,000 0,01623323 0,04542702 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01623323 0,04537504 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01623323 0,04532319 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01623323 0,04527145 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01623323 0,04521983 ! adrenal gland development GO:0030325 17 7 0,000 0,01623323 0,04516832 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01623323 0,04511694 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01623323 0,04506567 ! ovulation GO:0030728 10 7 0,000 0,01623323 0,04501451 ! adenohypophysis development GO:0021984 11 7 0,000 0,01623323 0,04496348 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01623323 0,04491256 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01623323 0,04486175 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01623323 0,04481106 ! microtubule nucleation GO:0007020 21 7 0,000 0,01623323 0,04476048 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01623323 0,04471002 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01623323 0,04465967 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01623323 0,04460943 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01623323 0,04455931 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01623323 0,0445093 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01623323 0,0444594 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01623323 0,04440962 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01623323 0,04435994 ! galactose metabolic process GO:0006012 13 7 0,000 0,01623323 0,04431038 ! vesicle fusion GO:0006906 20 7 0,000 0,01623323 0,04426092 ! response to dietary excess GO:0002021 8 7 0,000 0,01623323 0,04421158 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01623323 0,04416235 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01623323 0,04411322 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01623323 0,04406421 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01623323 0,0440153 ! organ growth GO:0035265 15 7 0,000 0,01623323 0,04396651 ! nucleoside transport GO:0015858 11 7 0,000 0,01623323 0,04391782 ! nucleoside salvage GO:0043174 11 7 0,000 0,01623323 0,04386923 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01623323 0,04382076 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01623323 0,04377239 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01623323 0,04372413 ! parturition GO:0007567 16 7 0,000 0,01623323 0,04367598 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01623323 0,04362793 ! rRNA modification GO:0000154 14 7 0,000 0,01623323 0,04357999 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01623323 0,04353215 ! spindle checkpoint GO:0031577 16 7 0,000 0,01623323 0,04348442 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01623323 0,04343679 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01623323 0,04338926 ! monocyte differentiation GO:0030224 16 7 0,000 0,01623323 0,04334184 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01623323 0,04329453 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01623323 0,04324731 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01623323 0,0432002 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01623323 0,0431532 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01623323 0,04310629 ! fibrinolysis GO:0042730 11 7 0,000 0,01623323 0,04305949 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01623323 0,04301278 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01623323 0,04296618 ! eating behavior GO:0042755 8 7 0,000 0,01623323 0,04291968 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01623323 0,04287328 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01623323 0,04282698 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01623323 0,04278078 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01623323 0,04273468 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01623323 0,04268868 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01623323 0,04264278 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01623323 0,04259698 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01623323 0,04255127 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01623323 0,04250567 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01623323 0,04246016 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01623323 0,04241475 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01623323 0,04236943 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01623323 0,04232421 ! histone ubiquitination GO:0016574 9 7 0,000 0,01623323 0,04227909 ! regulation of meiosis GO:0040020 12 7 0,000 0,01623323 0,04223407 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01623323 0,04218914 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01623323 0,0421443 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01623323 0,04209956 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01623323 0,04205492 ! transcription termination GO:0006353 14 7 0,000 0,01623323 0,04201037 ! anaphase GO:0051322 18 7 0,000 0,01623323 0,04196591 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01623323 0,04192155 ! axonal fasciculation GO:0007413 19 7 0,000 0,01623323 0,04187728 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01623323 0,04183311 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01623323 0,04178903 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01623323 0,04174504 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01623323 0,04170114 ! diuresis GO:0030146 12 7 0,000 0,01623323 0,04165734 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01623323 0,04161363 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01623323 0,04157001 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01623323 0,04152648 ! antibiotic transport GO:0042891 9 7 0,000 0,01623323 0,04148304 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01623323 0,04143969 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01623323 0,04139644 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01623323 0,04135327 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01623323 0,0413102 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01623323 0,04126721 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01623323 0,04122431 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01623323 0,0411815 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01623323 0,04113878 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01623323 0,04109615 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01623323 0,04105361 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01623323 0,04101116 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01623323 0,04096879 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01623323 0,04092651 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01623323 0,04088432 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01623323 0,04084221 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01623323 0,04080019 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01623323 0,04075826 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01623323 0,04071641 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01623323 0,04067465 ! muscle adaptation GO:0043500 13 7 0,000 0,01623323 0,04063298 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01623323 0,04059139 ! retina homeostasis GO:0001895 12 7 0,000 0,01623323 0,04054989 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01623323 0,04050847 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01623323 0,04046713 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01623323 0,04042588 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01623323 0,04038471 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,01696745 0,04216835 ! mitochondrion organization GO:0007005 159 87 1,000 0,01772697 0,04401116 ! alcohol catabolic process GO:0046164 142 87 1,000 0,01772697 0,04396648 ! regulation of protein transport GO:0051223 165 87 1,000 0,01772697 0,04392189 GO:0070201|regulation of establishment of protein localization, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01853091 0,04586729 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01853091 0,04582087 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01853091 0,04577454 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01853091 0,0457283 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01853091 0,04568216 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01853091 0,04563611 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01853091 0,04559015 ! male meiosis GO:0007140 9 8 0,000 0,01853091 0,04554428 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01853091 0,04549851 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01853091 0,04545283 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01853091 0,04540724 ! meiotic prophase I GO:0007128 14 8 0,000 0,01853091 0,04536174 ! response to zinc ion GO:0010043 12 8 0,000 0,01853091 0,04531634 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01853091 0,04527102 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01853091 0,04522579 ! oligopeptide transport GO:0006857 16 8 0,000 0,01853091 0,04518066 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01853091 0,04513561 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01853091 0,04509066 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01853091 0,04504579 ! signal peptide processing GO:0006465 12 8 0,000 0,01853091 0,04500101 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01853091 0,04495632 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01853091 0,04491173 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01853091 0,04486721 ! succinate metabolic process GO:0006105 17 8 0,000 0,01853091 0,04482279 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01853091 0,04477846 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01853091 0,04473421 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01853091 0,04469005 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01853091 0,04464598 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01853091 0,04460199 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01853091 0,04455809 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01853091 0,04451428 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01853091 0,04447055 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01853091 0,04442691 ! reflex GO:0060004 17 8 0,000 0,01853091 0,04438335 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01853091 0,04433988 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01853091 0,0442965 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01853091 0,0442532 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01853091 0,04420998 ! pigment granule organization GO:0048753 17 8 0,000 0,01853091 0,04416685 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01853091 0,0441238 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01853091 0,04408084 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01853091 0,04403796 ! histidine catabolic process GO:0006548 10 8 0,000 0,01853091 0,04399516 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01853091 0,04395245 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01853091 0,04390981 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01853091 0,04386727 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01853091 0,0438248 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01853091 0,04378242 ! melanin metabolic process GO:0006582 17 8 0,000 0,01853091 0,04374012 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01853091 0,04369789 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01853091 0,04365576 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01853091 0,0436137 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01853091 0,04357172 ! macrophage activation GO:0042116 13 8 0,000 0,01853091 0,04352983 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01853091 0,04348801 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01853091 0,04344628 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01853091 0,04340462 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01853091 0,04336305 ! purine salvage GO:0043101 12 8 0,000 0,01853091 0,04332155 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01853091 0,04328013 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01853091 0,0432388 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01853091 0,04319754 ! osteoblast development GO:0002076 17 8 0,000 0,01853091 0,04315636 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01853091 0,04311526 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01853091 0,04307423 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01853091 0,04303329 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01853091 0,04299242 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01853091 0,04295163 ! response to UV-B GO:0010224 17 8 0,000 0,01853091 0,04291092 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01853091 0,04287028 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01853091 0,04282972 ! intermediate filament organization GO:0045109 12 8 0,000 0,01853091 0,04278924 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01853091 0,04274884 ! cellular extravasation GO:0045123 13 8 0,000 0,01853091 0,04270851 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01853091 0,04266826 ! response to antibiotic GO:0046677 11 8 0,000 0,01853091 0,04262808 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01853091 0,04258798 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01853091 0,04254795 ! DNA topological change GO:0006265 12 8 0,000 0,01853091 0,042508 ! response to tropane GO:0014073 15 8 0,000 0,01853091 0,04246812 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01853091 0,04242832 ! melanosome transport GO:0032402 13 8 0,000 0,01853091 0,04238859 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01853091 0,04234894 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01853091 0,04230936 ! mast cell activation GO:0045576 14 8 0,000 0,01853091 0,04226986 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01853091 0,04223043 ! gas homeostasis GO:0033483 14 8 0,000 0,01853091 0,04219107 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01853091 0,04215179 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01853091 0,04211258 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01853091 0,04207344 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01853091 0,04203437 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01853091 0,04199538 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01853091 0,04195646 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01853091 0,04191761 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01853091 0,04187883 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01853091 0,04184013 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01853091 0,04180149 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01853091 0,04176293 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01853091 0,04172444 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01853091 0,04168602 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01853091 0,04164767 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01853091 0,04160939 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01853091 0,04157118 ! hormone catabolic process GO:0042447 17 8 0,000 0,01853091 0,04153305 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01853091 0,04149498 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01853091 0,04145698 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01853091 0,04141905 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01853091 0,04138119 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01853091 0,0413434 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01853091 0,04130567 ! adult feeding behavior GO:0008343 10 8 0,000 0,01853091 0,04126802 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01853091 0,04123044 ! blastocyst growth GO:0001832 19 8 0,000 0,01853091 0,04119292 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01853091 0,04115547 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01853091 0,04111809 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01853091 0,04108078 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01853091 0,04104353 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01853091 0,04100636 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01853091 0,04096925 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01853091 0,04093221 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01853091 0,04089523 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01853091 0,04085832 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01853091 0,04082148 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01853091 0,0407847 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01853091 0,04074799 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01853091 0,04071135 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01853091 0,04067477 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01853091 0,04063826 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01853091 0,04060181 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01853091 0,04056543 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01853091 0,04052911 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01853091 0,04049286 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,01889286 0,04124687 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,02009025 0,04382185 ! amine transport GO:0015837 181 93 1,000 0,02009025 0,04378276 ! axon extension GO:0048675 16 9 0,000 0,02082329 0,04533984 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02082329 0,04529946 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02082329 0,04525916 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02082329 0,04521893 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02082329 0,04517877 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02082329 0,04513868 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02082329 0,04509867 ! reproductive behavior GO:0019098 22 9 0,000 0,02082329 0,04505872 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02082329 0,04501885 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02082329 0,04497904 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02082329 0,04493931 ! UTP metabolic process GO:0046051 10 9 0,000 0,02082329 0,04489965 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02082329 0,04486005 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02082329 0,04482053 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02082329 0,04478107 ! artery development GO:0060840 25 9 0,000 0,02082329 0,04474169 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02082329 0,04470237 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02082329 0,04466312 ! equilibrioception GO:0050957 20 9 0,000 0,02082329 0,04462395 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02082329 0,04458484 ! chemosensory behavior GO:0007635 21 9 0,000 0,02082329 0,04454579 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02082329 0,04450682 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02082329 0,04446792 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02082329 0,04442908 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02082329 0,04439031 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02082329 0,04435161 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02082329 0,04431298 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02082329 0,04427441 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02082329 0,04423591 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02082329 0,04419748 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02082329 0,04415911 ! protein targeting to ER GO:0045047 25 9 0,000 0,02082329 0,04412081 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02082329 0,04408258 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02082329 0,04404441 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02082329 0,04400631 ! glycine catabolic process GO:0006546 15 9 0,000 0,02082329 0,04396828 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02082329 0,04393031 ! endosome organization GO:0007032 20 9 0,000 0,02082329 0,04389241 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02082329 0,04385457 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02082329 0,04381679 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02082329 0,04377909 ! mannose metabolic process GO:0006013 13 9 0,000 0,02082329 0,04374144 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02082329 0,04370386 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02082329 0,04366635 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02082329 0,0436289 ! receptor clustering GO:0043113 20 9 0,000 0,02082329 0,04359151 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02082329 0,04355419 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02082329 0,04351694 ! retinol metabolic process GO:0042572 20 9 0,000 0,02082329 0,04347974 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02082329 0,04344261 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02082329 0,04340554 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02082329 0,04336854 ! macrophage differentiation GO:0030225 15 9 0,000 0,02082329 0,0433316 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02082329 0,04329472 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02082329 0,04325791 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02082329 0,04322115 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02082329 0,04318446 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02082329 0,04314784 ! response to amine stimulus GO:0014075 13 9 0,000 0,02082329 0,04311127 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02082329 0,04307477 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02082329 0,04303832 ! erythrocyte development GO:0048821 17 9 0,000 0,02082329 0,04300194 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02082329 0,04296562 ! renal water homeostasis GO:0003091 15 9 0,000 0,02082329 0,04292937 ! postreplication repair GO:0006301 25 9 0,000 0,02082329 0,04289317 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02082329 0,04285703 ! icosanoid secretion GO:0032309 15 9 0,000 0,02082329 0,04282096 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02082329 0,04278494 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02082329 0,04274899 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02082329 0,0427131 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02082329 0,04267726 ! sterol catabolic process GO:0016127 14 9 0,000 0,02082329 0,04264149 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02082329 0,04260578 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02082329 0,04257012 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02082329 0,04253453 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02082329 0,042499 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02082329 0,04246352 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02082329 0,0424281 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02082329 0,04239275 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02082329 0,04235745 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02082329 0,04232221 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02082329 0,04228703 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02082329 0,04225191 ! purine base metabolic process GO:0006144 25 9 0,000 0,02082329 0,04221684 ! pigment granule transport GO:0051904 17 9 0,000 0,02082329 0,04218184 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02082329 0,04214689 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02082329 0,042112 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02082329 0,04207717 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02082329 0,04204239 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02082329 0,04200768 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02082329 0,04197302 ! mitochondrion localization GO:0051646 18 9 0,000 0,02082329 0,04193842 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,02090577 0,04206985 ! regulation of T cell activation GO:0050863 175 96 1,000 0,02131866 0,04286541 ! regulation of protein localization GO:0032880 188 97 1,000 0,02173493 0,04366648 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,02300395 0,04617802 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 1,000 0,02300395 0,04614011 ! positive regulation of immune response GO:0050778 175 100 1,000 0,02300395 0,04610226 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02311038 0,04627758 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02311038 0,04623968 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02311038 0,04620184 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02311038 0,04616407 ! associative learning GO:0008306 21 10 0,000 0,02311038 0,04612635 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02311038 0,0460887 ! phosphate transport GO:0006817 24 10 0,000 0,02311038 0,0460511 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02311038 0,04601357 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02311038 0,0459761 ! CTP metabolic process GO:0046036 11 10 0,000 0,02311038 0,04593869 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02311038 0,04590134 ! GTP metabolic process GO:0046039 11 10 0,000 0,02311038 0,04586406 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02311038 0,04582683 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02311038 0,04578966 ! social behavior GO:0035176 29 10 0,000 0,02311038 0,04575256 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02311038 0,04571551 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02311038 0,04567852 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02311038 0,0456416 ! androgen metabolic process GO:0008209 17 10 0,000 0,02311038 0,04560473 ! phospholipid efflux GO:0033700 19 10 0,000 0,02311038 0,04556792 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02311038 0,04553117 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02311038 0,04549448 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02311038 0,04545785 ! lung alveolus development GO:0048286 26 10 0,000 0,02311038 0,04542128 ! pathogenesis GO:0009405 17 10 0,000 0,02311038 0,04538477 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02311038 0,04534832 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02311038 0,04531192 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02311038 0,04527558 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02311038 0,04523931 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02311038 0,04520309 ! arginine catabolic process GO:0006527 17 10 0,000 0,02311038 0,04516692 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02311038 0,04513082 ! proline metabolic process GO:0006560 13 10 0,000 0,02311038 0,04509477 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02311038 0,04505878 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02311038 0,04502285 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02311038 0,04498697 ! V(D)J recombination GO:0033151 34 10 0,000 0,02311038 0,04495116 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02311038 0,0449154 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02311038 0,04487969 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02311038 0,04484405 ! B cell proliferation GO:0042100 19 10 0,000 0,02311038 0,04480846 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02311038 0,04477292 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02311038 0,04473744 ! multicellular organism growth GO:0035264 19 10 0,000 0,02311038 0,04470202 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02311038 0,04466666 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02311038 0,04463135 ! ruffle organization GO:0031529 17 10 0,000 0,02311038 0,04459609 ! epithelial cell development GO:0002064 21 10 0,000 0,02311038 0,04456089 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02311038 0,04452575 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02311038 0,04449066 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02311038 0,04445563 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02311038 0,04442066 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02311038 0,04438573 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02311038 0,04435087 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,02311038 0,04431605 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02311038 0,0442813 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02311038 0,04424659 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02311038 0,04421194 ! segment specification GO:0007379 15 10 0,000 0,02311038 0,04417735 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02311038 0,04414281 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02311038 0,04410832 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02311038 0,04407389 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02311038 0,04403951 ! response to dsRNA GO:0043331 23 10 0,000 0,02311038 0,04400519 ! DNA ligation GO:0006266 18 10 0,000 0,02311038 0,04397091 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02311038 0,0439367 ! melanosome localization GO:0032400 16 10 0,000 0,02311038 0,04390253 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02311038 0,04386842 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02311038 0,04383436 ! induction of an organ GO:0001759 17 10 0,000 0,02311038 0,04380035 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02311038 0,0437664 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02311038 0,0437325 ! protein sumoylation GO:0016925 17 10 0,000 0,02311038 0,04369865 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02311038 0,04366485 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02311038 0,04363111 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02311038 0,04359742 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02311038 0,04356378 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02311038 0,04353019 ! salivary gland development GO:0007431 28 10 0,000 0,02311038 0,04349665 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02311038 0,04346317 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02311038 0,04342973 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02311038 0,04339635 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02311038 0,04336302 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02311038 0,04332974 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02311038 0,04329651 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02311038 0,04326334 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02311038 0,04323021 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02311038 0,04319713 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02311038 0,04316411 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02311038 0,04313113 ! detection of calcium ion GO:0005513 24 10 0,000 0,02311038 0,04309821 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02311038 0,04306533 ! blastocyst formation GO:0001825 18 10 0,000 0,02311038 0,04303251 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02311038 0,04299974 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02311038 0,04296701 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02311038 0,04293434 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02311038 0,04290171 ! response to nicotine GO:0035094 20 10 0,000 0,02311038 0,04286914 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02311038 0,04283661 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02311038 0,04280413 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02539219 0,04699478 ! respiratory burst GO:0045730 17 11 0,000 0,02539219 0,04695921 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02539219 0,04692369 ! neuron fate specification GO:0048665 18 11 0,000 0,02539219 0,04688822 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02539219 0,04685281 ! thyroid gland development GO:0030878 26 11 0,000 0,02539219 0,04681745 ! synapsis GO:0007129 14 11 0,000 0,02539219 0,04678214 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02539219 0,04674688 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02539219 0,04671168 ! response to pain GO:0048265 27 11 0,000 0,02539219 0,04667654 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02539219 0,04664144 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02539219 0,0466064 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02539219 0,04657141 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02539219 0,04653647 ! bone resorption GO:0045453 16 11 0,000 0,02539219 0,04650159 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02539219 0,04646675 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02539219 0,04643197 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02539219 0,04639724 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02539219 0,04636257 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02539219 0,04632794 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02539219 0,04629337 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02539219 0,04625885 GO:0010833|telomere maintenance via telomere lengthening, ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02539219 0,04622438 ! UV protection GO:0009650 20 11 0,000 0,02539219 0,04618996 ! adult heart development GO:0007512 16 11 0,000 0,02539219 0,04615559 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02539219 0,04612128 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02539219 0,04608701 ! macroautophagy GO:0016236 19 11 0,000 0,02539219 0,0460528 ! temperature homeostasis GO:0001659 18 11 0,000 0,02539219 0,04601863 ! behavioral fear response GO:0001662 27 11 0,000 0,02539219 0,04598452 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02539219 0,04595046 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02539219 0,04591644 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02539219 0,04588248 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02539219 0,04584857 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02539219 0,04581471 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02539219 0,0457809 ! regulation of organ growth GO:0046620 14 11 0,000 0,02539219 0,04574714 ! pigment granule localization GO:0051875 20 11 0,000 0,02539219 0,04571342 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02539219 0,04567976 ! vasoconstriction GO:0042310 20 11 0,000 0,02539219 0,04564615 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02539219 0,04561258 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02539219 0,04557907 ! embryonic axis specification GO:0000578 19 11 0,000 0,02539219 0,04554561 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02539219 0,04551219 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02539219 0,04547882 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02539219 0,04544551 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02539219 0,04541224 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02539219 0,04537902 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02539219 0,04534584 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02539219 0,04531272 ! prophase GO:0051324 17 11 0,000 0,02539219 0,04527965 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02539219 0,04524662 ! nucleosome positioning GO:0016584 15 11 0,000 0,02539219 0,04521364 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02539219 0,04518071 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02539219 0,04514783 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02539219 0,04511499 ! apical protein localization GO:0045176 18 11 0,000 0,02539219 0,04508221 ! acid secretion GO:0046717 20 11 0,000 0,02539219 0,04504947 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02539219 0,04501677 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02539219 0,04498413 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02539219 0,04495153 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02539219 0,04491898 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02539219 0,04488648 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02539219 0,04485402 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02539219 0,04482162 ! cholesterol efflux GO:0033344 21 11 0,000 0,02539219 0,04478925 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02539219 0,04475694 ! oocyte development GO:0048599 20 11 0,000 0,02539219 0,04472467 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02539219 0,04469245 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02539219 0,04466027 ! embryonic gut development GO:0048566 19 11 0,000 0,02539219 0,04462814 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02539219 0,04459606 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02539219 0,04456402 ! activation of innate immune response GO:0002218 16 11 0,000 0,02539219 0,04453203 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02539219 0,04450008 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02539219 0,04446818 ! lysogeny GO:0030069 22 11 0,000 0,02539219 0,04443633 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02539219 0,04440452 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02539219 0,04437276 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02539219 0,04434104 ! nucleus localization GO:0051647 22 11 0,000 0,02539219 0,04430937 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02766873 0,04824748 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02766873 0,04821306 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02766873 0,0481787 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02766873 0,04814438 ! protein complex disassembly GO:0043241 28 12 0,000 0,02766873 0,04811012 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02766873 0,0480759 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02766873 0,04804173 ! hippocampus development GO:0021766 29 12 0,000 0,02766873 0,04800761 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02766873 0,04797354 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02766873 0,04793951 ! T cell proliferation GO:0042098 32 12 0,000 0,02766873 0,04790554 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02766873 0,04787161 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02766873 0,04783773 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02766873 0,0478039 ! drug transport GO:0015893 16 12 0,000 0,02766873 0,04777012 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02766873 0,04773638 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02766873 0,04770269 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02766873 0,04766905 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02766873 0,04763546 ! focal adhesion formation GO:0048041 37 12 0,000 0,02766873 0,04760191 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02766873 0,04756841 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02766873 0,04753496 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02766873 0,04750156 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02766873 0,0474682 ! lipid digestion GO:0044241 21 12 0,000 0,02766873 0,04743489 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02766873 0,04740162 ! entry into host cell GO:0030260 34 12 0,000 0,02766873 0,0473684 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02766873 0,04733523 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02766873 0,04730211 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02766873 0,04726903 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02766873 0,047236 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02766873 0,04720301 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02766873 0,04717007 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02766873 0,04713718 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02766873 0,04710433 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02766873 0,04707153 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02766873 0,04703877 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02766873 0,04700606 ! cranial nerve development GO:0021545 23 12 0,000 0,02766873 0,04697339 ! fucose catabolic process GO:0019317 25 12 0,000 0,02766873 0,04694077 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02766873 0,0469082 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02766873 0,04687567 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02766873 0,04684318 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02766873 0,04681074 ! zymogen activation GO:0031638 18 12 0,000 0,02766873 0,04677835 ! T cell homeostasis GO:0043029 28 12 0,000 0,02766873 0,046746 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02766873 0,04671369 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02766873 0,04668143 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02766873 0,04664922 ! oocyte differentiation GO:0009994 21 12 0,000 0,02766873 0,04661704 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02766873 0,04658492 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02766873 0,04655283 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02766873 0,04652079 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02766873 0,0464888 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02766873 0,04645685 ! defense response to fungus GO:0050832 15 12 0,000 0,02766873 0,04642494 ! developmental induction GO:0031128 22 12 0,000 0,02766873 0,04639308 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02766873 0,04636126 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02766873 0,04632948 ! response to cold GO:0009409 17 12 0,000 0,02766873 0,04629775 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02766873 0,04626606 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02766873 0,04623441 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02994002 0,04999554 ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02994002 0,04996139 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02994002 0,04992729 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02994002 0,04989323 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02994002 0,04985922 ! peroxisomal transport GO:0043574 28 13 0,000 0,02994002 0,04982526 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02994002 0,04979134 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02994002 0,04975747 ! organelle fusion GO:0048284 36 13 0,000 0,02994002 0,04972364 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02994002 0,04968986 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02994002 0,04965613 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02994002 0,04962244 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02994002 0,0495888 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02994002 0,0495552 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02994002 0,04952165 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02994002 0,04948814 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02994002 0,04945468 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02994002 0,04942127 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02994002 0,0493879 ! methionine metabolic process GO:0006555 31 13 0,000 0,02994002 0,04935457 ! plasma membrane organization GO:0007009 27 13 0,000 0,02994002 0,04932129 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02994002 0,04928806 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02994002 0,04925487 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02994002 0,04922172 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,02994002 0,04918862 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02994002 0,04915556 ! exocrine system development GO:0035272 34 13 0,000 0,02994002 0,04912255 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02994002 0,04908958 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02994002 0,04905666 GO:0006509|membrane protein ectodomain proteolysis, ! L-glutamate transport GO:0015813 30 13 0,000 0,02994002 0,04902378 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02994002 0,04899094 ! protein homotetramerization GO:0051289 24 13 0,000 0,02994002 0,04895815 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02994002 0,0489254 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02994002 0,0488927 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02994002 0,04886004 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02994002 0,04882742 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02994002 0,04879485 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02994002 0,04876232 ! histone methylation GO:0016571 29 13 0,000 0,02994002 0,04872983 ! chromatin silencing GO:0006342 29 13 0,000 0,02994002 0,04869739 ! gland morphogenesis GO:0022612 31 13 0,000 0,02994002 0,04866499 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02994002 0,04863263 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02994002 0,04860032 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02994002 0,04856805 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02994002 0,04853582 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02994002 0,04850363 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02994002 0,04847149 ! spleen development GO:0048536 24 13 0,000 0,02994002 0,04843939 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02994002 0,04840733 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02994002 0,04837531 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02994002 0,04834334 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02994002 0,04831141 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02994002 0,04827952 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02994002 0,04824768 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02994002 0,04821587 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02994002 0,04818411 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02994002 0,04815239 ! insulin secretion GO:0030073 24 13 0,000 0,02994002 0,04812071 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02994002 0,04808907 ! acrosome reaction GO:0007340 19 13 0,000 0,02994002 0,04805747 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02994002 0,04802592 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02994002 0,04799441 ! rRNA transcription GO:0009303 28 14 0,000 0,03220607 0,05159307 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03220607 0,05155926 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03220607 0,0515255 ! water transport GO:0006833 21 14 0,000 0,03220607 0,05149178 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03220607 0,0514581 ! non-recombinational repair GO:0000726 29 14 0,000 0,03220607 0,05142447 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03220607 0,05139088 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03220607 0,05135733 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03220607 0,05132383 ! lipid localization GO:0010876 32 14 0,000 0,03220607 0,05129037 GO:0019915|lipid storage, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03220607 0,05125696 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03220607 0,05122359 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03220607 0,05119026 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03220607 0,05115698 ! arginine metabolic process GO:0006525 21 14 0,000 0,03220607 0,05112374 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03220607 0,05109054 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03220607 0,05105739 ! regulation of heart rate GO:0002027 25 14 0,000 0,03220607 0,05102428 ! fear response GO:0042596 34 14 0,000 0,03220607 0,05099121 ! organic alcohol transport GO:0015850 29 14 0,000 0,03220607 0,05095818 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03220607 0,0509252 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03220607 0,05089226 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03220607 0,05085936 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03220607 0,05082651 ! bone mineralization GO:0030282 18 14 0,000 0,03220607 0,05079369 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03220607 0,05076092 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03220607 0,0507282 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03220607 0,05069551 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03220607 0,05066287 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03220607 0,05063027 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03220607 0,05059771 ! ribosome assembly GO:0042255 18 14 0,000 0,03220607 0,05056519 ! cerebellum development GO:0021549 23 14 0,000 0,03220607 0,05053271 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03220607 0,05050028 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03220607 0,05046789 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03220607 0,05043553 ! NADP metabolic process GO:0006739 24 14 0,000 0,03220607 0,05040322 ! oxygen transport GO:0015671 22 14 0,000 0,03220607 0,05037096 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03220607 0,05033873 ! male genitalia development GO:0030539 26 14 0,000 0,03220607 0,05030654 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03220607 0,0502744 ! regulation of axon extension GO:0030516 43 14 0,000 0,03220607 0,05024229 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03220607 0,05021023 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03446689 0,05370065 ! lactation GO:0007595 30 15 0,000 0,03446689 0,05366642 ! reproductive cellular process GO:0048610 22 15 0,000 0,03446689 0,05363224 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03446689 0,0535981 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03446689 0,053564 ! superoxide anion generation GO:0042554 22 15 0,000 0,03446689 0,05352995 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03446689 0,05349594 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03446689 0,05346198 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03446689 0,05342805 ! copper ion transport GO:0006825 22 15 0,000 0,03446689 0,05339417 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03446689 0,05336034 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03446689 0,05332654 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03446689 0,05329279 ! sulfate transport GO:0008272 27 15 0,000 0,03446689 0,05325909 ! response to cAMP GO:0051591 25 15 0,000 0,03446689 0,05322542 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03446689 0,0531918 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03446689 0,05315822 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03446689 0,05312468 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03446689 0,05309118 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03446689 0,05305773 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03446689 0,05302432 ! vesicle coating GO:0006901 38 15 0,000 0,03446689 0,05299095 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03446689 0,05295762 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03446689 0,05292433 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03446689 0,05289109 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03446689 0,05285789 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03446689 0,05282473 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03446689 0,05279161 ! histone deacetylation GO:0016575 24 15 0,000 0,03446689 0,05275853 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03446689 0,05272549 ! water homeostasis GO:0030104 28 15 0,000 0,03446689 0,0526925 ! cofactor transport GO:0051181 30 15 0,000 0,03446689 0,05265955 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03446689 0,05262663 ! muscle maintenance GO:0046716 26 15 0,000 0,03446689 0,05259376 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03446689 0,05256093 ! intestinal absorption GO:0050892 31 15 0,000 0,03446689 0,05252814 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03446689 0,0524954 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03446689 0,05246269 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03446689 0,05243002 ! cell killing GO:0001906 32 15 0,000 0,03446689 0,05239739 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03446689 0,05236481 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03446689 0,05233226 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03446689 0,05229976 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03446689 0,0522673 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03446689 0,05223487 ! actin filament polymerization GO:0030041 27 15 0,000 0,03446689 0,05220249 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03446689 0,05217014 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03672249 0,05554987 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03672249 0,0555155 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03672249 0,05548117 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03672249 0,05544688 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03672249 0,05541263 ! bone remodeling GO:0046849 28 16 0,000 0,03672249 0,05537842 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03672249 0,05534426 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03672249 0,05531014 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03672249 0,05527606 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03672249 0,05524202 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03672249 0,05520803 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03672249 0,05517408 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03672249 0,05514016 ! startle response GO:0001964 28 16 0,000 0,03672249 0,05510629 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03672249 0,05507247 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03672249 0,05503868 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03672249 0,05500493 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03672249 0,05497123 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03672249 0,05493757 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03672249 0,05490395 ! pituitary gland development GO:0021983 30 16 0,000 0,03672249 0,05487037 ! response to osmotic stress GO:0006970 27 16 0,000 0,03672249 0,05483683 ! lysosomal transport GO:0007041 31 16 0,000 0,03672249 0,05480333 ! fructose metabolic process GO:0006000 25 16 0,000 0,03672249 0,05476987 ! L-amino acid transport GO:0015807 33 16 0,000 0,03672249 0,05473645 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03672249 0,05470308 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03672249 0,05466974 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03672249 0,05463645 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03672249 0,05460319 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03672249 0,05456998 ! axon cargo transport GO:0008088 46 16 0,000 0,03672249 0,05453681 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03672249 0,05450367 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03672249 0,05447058 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03672249 0,05443753 ! DNA replication initiation GO:0006270 28 16 0,000 0,03672249 0,05440452 ! neuron recognition GO:0008038 40 16 0,000 0,03672249 0,05437154 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03672249 0,05433861 ! tissue regeneration GO:0042246 27 16 0,000 0,03672249 0,05430572 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03672249 0,05427287 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03672249 0,05424005 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03672249 0,05420728 ! biomineral formation GO:0031214 22 16 0,000 0,03672249 0,05417455 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03672249 0,05414185 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03672249 0,0541092 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03672249 0,05407658 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03672249 0,054044 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03672249 0,05401147 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03672249 0,05397897 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03672249 0,05394651 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03672249 0,05391409 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,03672249 0,05388171 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03897289 0,05714932 ! metencephalon development GO:0022037 32 17 0,000 0,03897289 0,05711503 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03897289 0,05708079 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03897289 0,05704659 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03897289 0,05701243 ! signal complex assembly GO:0007172 47 17 0,000 0,03897289 0,05697831 ! filopodium assembly GO:0046847 42 17 0,000 0,03897289 0,05694424 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03897289 0,0569102 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03897289 0,0568762 ! glial cell development GO:0021782 28 17 0,000 0,03897289 0,05684225 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03897289 0,05680833 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03897289 0,05677446 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03897289 0,05674062 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03897289 0,05670683 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03897289 0,05667307 ! myoblast differentiation GO:0045445 50 17 0,000 0,03897289 0,05663936 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03897289 0,05660568 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03897289 0,05657205 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03897289 0,05653846 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03897289 0,0565049 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03897289 0,05647139 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03897289 0,05643791 ! membrane budding GO:0006900 42 17 0,000 0,03897289 0,05640448 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03897289 0,05637108 ! regulation of protein binding GO:0043393 33 17 0,000 0,03897289 0,05633773 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03897289 0,05630441 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03897289 0,05627114 ! genitalia development GO:0048806 32 17 0,000 0,03897289 0,0562379 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03897289 0,0562047 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03897289 0,05617154 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03897289 0,05613842 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03897289 0,05610534 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03897289 0,0560723 ! steroid catabolic process GO:0006706 34 17 0,000 0,03897289 0,05603929 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03897289 0,05600633 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03897289 0,0559734 ! gas transport GO:0015669 26 17 0,000 0,03897289 0,05594052 ! organic cation transport GO:0015695 32 17 0,000 0,03897289 0,05590767 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03897289 0,05587486 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03897289 0,05584209 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04121809 0,05902449 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04121809 0,05898992 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04121809 0,05895538 ! limbic system development GO:0021761 40 18 0,000 0,04121809 0,05892088 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04121809 0,05888643 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04121809 0,05885201 ! adult walking behavior GO:0007628 36 18 0,000 0,04121809 0,05881763 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04121809 0,0587833 ! heart looping GO:0001947 34 18 0,000 0,04121809 0,058749 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04121809 0,05871474 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04121809 0,05868053 ! centrosome cycle GO:0007098 26 18 0,000 0,04121809 0,05864635 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04121809 0,05861222 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04121809 0,05857812 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04121809 0,05854406 ! glycine metabolic process GO:0006544 30 18 0,000 0,04121809 0,05851005 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04121809 0,05847607 ! response to retinoic acid GO:0032526 31 18 0,000 0,04121809 0,05844213 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04121809 0,05840823 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04121809 0,05837437 ! DNA integration GO:0015074 32 18 0,000 0,04121809 0,05834055 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04121809 0,05830677 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04121809 0,05827303 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04121809 0,05823932 ! neural crest cell migration GO:0001755 41 18 0,000 0,04121809 0,05820566 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04121809 0,05817203 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04121809 0,05813845 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04121809 0,0581049 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04121809 0,05807139 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04121809 0,05803792 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04121809 0,05800449 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04121809 0,05797109 ! detection of bacterium GO:0016045 22 18 0,000 0,04121809 0,05793774 ! nerve development GO:0021675 34 18 0,000 0,04121809 0,05790442 ! defense response to virus GO:0051607 43 18 0,000 0,04121809 0,05787114 ! microspike assembly GO:0030035 46 18 0,000 0,04121809 0,0578379 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04121809 0,0578047 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04121809 0,05777154 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04345811 0,06087623 ! positive regulation of translation GO:0045727 31 19 0,000 0,04345811 0,06084135 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04345811 0,0608065 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04345811 0,0607717 ! neuron maturation GO:0042551 46 19 0,000 0,04345811 0,06073693 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04345811 0,0607022 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04345811 0,06066752 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04345811 0,06063287 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04345811 0,06059826 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04345811 0,06056369 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04345811 0,06052916 ! memory GO:0007613 34 19 0,000 0,04345811 0,06049467 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04345811 0,06046022 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04345811 0,06042581 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04345811 0,06039144 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04345811 0,06035711 ! cerebral cortex development GO:0021987 40 19 0,000 0,04345811 0,06032281 ! pigmentation during development GO:0048066 42 19 0,000 0,04345811 0,06028856 ! response to vitamin A GO:0033189 32 19 0,000 0,04345811 0,06025434 ! heme metabolic process GO:0042168 40 19 0,000 0,04345811 0,06022017 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04345811 0,06018603 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04345811 0,06015193 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04345811 0,06011787 ! response to fungus GO:0009620 26 19 0,000 0,04345811 0,06008384 ! peptide cross-linking GO:0018149 39 19 0,000 0,04345811 0,06004986 ! protein export from nucleus GO:0006611 40 19 0,000 0,04345811 0,06001591 ! heart process GO:0003015 32 19 0,000 0,04345811 0,05998201 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04345811 0,05994814 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04345811 0,05991431 ! visual learning GO:0008542 38 19 0,000 0,04345811 0,05988051 ! cellular pigmentation GO:0033059 37 19 0,000 0,04345811 0,05984676 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04345811 0,05981304 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04345811 0,05977937 ! vitamin transport GO:0051180 31 19 0,000 0,04345811 0,05974572 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04345811 0,05971212 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04345811 0,05967856 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04345811 0,05964503 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04345811 0,05961154 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04345811 0,05957809 ! cilium assembly GO:0042384 38 19 0,000 0,04345811 0,05954467 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04345811 0,0595113 ! protein secretion GO:0009306 45 20 0,000 0,04569295 0,06253663 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04569295 0,06250162 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04569295 0,06246664 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04569295 0,0624317 ! skin development GO:0043588 42 20 0,000 0,04569295 0,06239681 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04569295 0,06236195 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04569295 0,06232713 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04569295 0,06229235 ! response to vitamin GO:0033273 36 20 0,000 0,04569295 0,06225761 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04569295 0,0622229 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04569295 0,06218824 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04569295 0,06215361 ! response to alkaloid GO:0043279 38 20 0,000 0,04569295 0,06211902 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04569295 0,06208448 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04569295 0,06204996 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04569295 0,06201549 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04569295 0,06198106 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04569295 0,06194666 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,04569295 0,06191231 ! body fluid secretion GO:0007589 33 20 0,000 0,04569295 0,06187799 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04569295 0,0618437 ! peptide secretion GO:0002790 38 20 0,000 0,04569295 0,06180946 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04569295 0,06177526 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04569295 0,06174109 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04569295 0,06170696 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04569295 0,06167287 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04569295 0,06163881 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04569295 0,06160479 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04569295 0,06157081 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04569295 0,06153687 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04569295 0,06150297 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04569295 0,0614691 ! regulation of glucose import GO:0046324 30 20 0,000 0,04569295 0,06143527 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04569295 0,06140148 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04569295 0,06136772 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04569295 0,061334 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04569295 0,06130032 ! regulation of cell killing GO:0031341 46 21 0,000 0,04792264 0,06425632 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04792264 0,06422107 ! hormone secretion GO:0046879 39 21 0,000 0,04792264 0,06418586 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04792264 0,06415069 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04792264 0,06411556 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04792264 0,06408047 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04792264 0,06404541 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04792264 0,0640104 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04792264 0,06397542 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04792264 0,06394048 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04792264 0,06390558 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04792264 0,06387071 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04792264 0,06383589 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04792264 0,0638011 ! sensory perception of pain GO:0019233 33 21 0,000 0,04792264 0,06376635 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04792264 0,06373164 ! diencephalon development GO:0021536 36 21 0,000 0,04792264 0,06369696 ! collagen fibril organization GO:0030199 62 21 0,000 0,04792264 0,06366233 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04792264 0,06362773 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04792264 0,06359317 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04792264 0,06355864 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04792264 0,06352416 ! collagen catabolic process GO:0030574 29 21 0,000 0,04792264 0,06348971 ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04792264 0,06345529 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04792264 0,06342092 ! actin filament-based movement GO:0030048 47 21 0,000 0,04792264 0,06338658 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,05014719 0,06629306 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,05014719 0,06625721 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,05014719 0,06622139 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,05014719 0,06618562 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,05014719 0,06614988 ! microtubule-based transport GO:0010970 59 22 0,000 0,05014719 0,06611418 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,05014719 0,06607852 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,05014719 0,0660429 ! vacuolar transport GO:0007034 41 22 0,000 0,05014719 0,06600731 ! central nervous system neuron development GO:0021954 47 22 0,000 0,05014719 0,06597177 ! fucose metabolic process GO:0006004 44 22 0,000 0,05014719 0,06593626 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,05014719 0,06590079 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,05014719 0,06586536 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,05014719 0,06582997 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,05014719 0,06579462 ! cytolysis GO:0019835 27 22 0,000 0,05014719 0,0657593 ! renal system process GO:0003014 42 22 0,000 0,05014719 0,06572402 ! vasodilation GO:0042311 40 22 0,000 0,05014719 0,06568878 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,05014719 0,06565358 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,05014719 0,06561841 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,05014719 0,06558328 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,05014719 0,06554819 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,05014719 0,06551314 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,05014719 0,06547813 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,05014719 0,06544315 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,05014719 0,06540821 ! sarcomere organization GO:0045214 32 22 0,000 0,05014719 0,06537331 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,05014719 0,06533844 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,05014719 0,06530361 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,05014719 0,06526882 ! gut development GO:0048565 44 22 0,000 0,05014719 0,06523407 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,05014719 0,06519935 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,05014719 0,06516467 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,05014719 0,06513002 ! protein stabilization GO:0050821 41 22 0,000 0,05014719 0,06509542 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05236659 0,0679403 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05236659 0,06790424 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05236659 0,06786822 ! gluconeogenesis GO:0006094 38 23 0,000 0,05236659 0,06783223 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05236659 0,06779628 ! viral genome replication GO:0019079 44 23 0,000 0,05236659 0,06776037 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05236659 0,0677245 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05236659 0,06768867 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,05236659 0,06765288 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05236659 0,06761712 ! regeneration GO:0031099 42 23 0,000 0,05236659 0,0675814 ! visual behavior GO:0007632 46 23 0,000 0,05236659 0,06754572 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05236659 0,06751007 ! response to ethanol GO:0045471 47 23 0,000 0,05236659 0,06747447 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05236659 0,0674389 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05236659 0,06740336 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05236659 0,06736787 ! peroxisome organization GO:0007031 43 23 0,000 0,05236659 0,06733241 ! lysosome organization GO:0007040 47 23 0,000 0,05236659 0,06729699 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05236659 0,06726161 ! vesicle targeting GO:0006903 49 23 0,000 0,05236659 0,06722627 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05236659 0,06719096 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05236659 0,06715569 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05236659 0,06712045 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05236659 0,06708526 ! DNA modification GO:0006304 36 23 0,000 0,05236659 0,0670501 ! fatty acid transport GO:0015908 47 23 0,000 0,05236659 0,06701497 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05236659 0,06697989 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05236659 0,06694484 ! hormone transport GO:0009914 41 23 0,000 0,05236659 0,06690983 ! cell-cell recognition GO:0009988 28 23 0,000 0,05236659 0,06687485 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05236659 0,06683991 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05236659 0,06680501 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05236659 0,06677014 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05458088 0,06955716 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05458088 0,0695209 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,05458088 0,06948467 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05458088 0,06944848 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05458088 0,06941233 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05458088 0,06937621 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05458088 0,06934014 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05458088 0,0693041 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05458088 0,06926809 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05458088 0,06923213 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05458088 0,0691962 ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,05458088 0,06916031 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05458088 0,06912446 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05458088 0,06908864 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05458088 0,06905286 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05458088 0,06901712 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05458088 0,06898142 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05458088 0,06894575 ! membrane depolarization GO:0051899 45 24 0,000 0,05458088 0,06891012 ! pallium development GO:0021543 56 24 0,000 0,05458088 0,06887453 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05458088 0,06883897 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05458088 0,06880345 ! platelet activation GO:0030168 41 24 0,000 0,05458088 0,06876796 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05458088 0,06873252 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05458088 0,06869711 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05458088 0,06866173 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05458088 0,06862639 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05458088 0,06859109 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05458088 0,06855583 ! regulation of amine transport GO:0051952 41 24 0,000 0,05458088 0,0685206 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,05458088 0,0684854 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,05679005 0,07122078 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,05679005 0,07118424 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,05679005 0,07114774 ! phototransduction GO:0007602 37 25 0,000 0,05679005 0,07111127 ! keratinization GO:0031424 37 25 0,000 0,05679005 0,07107484 ! vasculogenesis GO:0001570 49 25 0,000 0,05679005 0,07103845 ! vacuole organization GO:0007033 49 25 0,000 0,05679005 0,07100209 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,05679005 0,07096577 ! receptor metabolic process GO:0043112 53 25 0,000 0,05679005 0,07092949 ! chromosome condensation GO:0030261 48 25 0,000 0,05679005 0,07089325 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,05679005 0,07085704 ! regulation of behavior GO:0050795 48 25 0,000 0,05679005 0,07082087 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,05679005 0,07078474 ! immunoglobulin production GO:0002377 62 25 0,000 0,05679005 0,07074864 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,05679005 0,07071258 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,05679005 0,07067656 ! liver development GO:0001889 55 25 0,000 0,05679005 0,07064057 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05899412 0,07334485 ! myelination GO:0042552 50 26 0,000 0,05899412 0,07330755 ! initiation of viral infection GO:0019059 60 26 0,000 0,05899412 0,07327028 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05899412 0,07323305 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05899412 0,07319585 ! molting cycle process GO:0022404 52 26 0,000 0,05899412 0,0731587 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05899412 0,07312158 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05899412 0,0730845 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05899412 0,07304746 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05899412 0,07301045 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,05899412 0,07297349 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05899412 0,07293656 ! digestive system process GO:0022600 49 26 0,000 0,05899412 0,07289966 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05899412 0,07286281 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,05899412 0,07282599 ! neural crest cell development GO:0014032 59 26 0,000 0,05899412 0,07278921 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05899412 0,07275247 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05899412 0,07271576 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05899412 0,07267909 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05899412 0,07264246 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05899412 0,07260586 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05899412 0,0725693 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,05899412 0,07253278 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05899412 0,0724963 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05899412 0,07245985 ! blastocyst development GO:0001824 50 26 0,000 0,05899412 0,07242344 ! telomere organization GO:0032200 46 26 0,000 0,05899412 0,07238706 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05899412 0,07235072 ! neural tube closure GO:0001843 58 26 0,000 0,05899412 0,07231442 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05899412 0,07227815 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05899412 0,07224192 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0611931 0,07489717 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,0611931 0,07485967 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,0611931 0,0748222 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0611931 0,07478477 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0611931 0,07474738 ! iron ion transport GO:0006826 65 27 0,000 0,0611931 0,07471002 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0611931 0,0746727 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0611931 0,07463542 ! tube lumen formation GO:0035148 59 27 0,000 0,0611931 0,07459818 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,0611931 0,07456097 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,0611931 0,0745238 ! response to toxin GO:0009636 49 27 0,000 0,0611931 0,07448667 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,0611931 0,07444958 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,0611931 0,07441252 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0611931 0,0743755 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0611931 0,07433851 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,0611931 0,07430157 ! neuron fate commitment GO:0048663 52 28 0,000 0,06338701 0,07692721 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,06338701 0,07688901 ! vesicle docking GO:0048278 55 28 0,000 0,06338701 0,07685085 ! circadian rhythm GO:0007623 56 28 0,000 0,06338701 0,07681273 ! dendrite development GO:0016358 67 28 0,000 0,06338701 0,07677465 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,06338701 0,0767366 ! fat cell differentiation GO:0045444 57 28 0,000 0,06338701 0,0766986 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,06338701 0,07666063 ! sperm motility GO:0030317 37 28 0,000 0,06338701 0,07662269 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,06338701 0,0765848 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,06338701 0,07654694 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,06338701 0,07650912 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,06338701 0,07647134 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,06338701 0,0764336 ! glutathione metabolic process GO:0006749 42 28 0,000 0,06338701 0,07639589 ! lipid oxidation GO:0034440 48 28 0,000 0,06338701 0,07635822 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,06338701 0,07632058 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,06557585 0,07891714 ! translational initiation GO:0006413 66 29 0,000 0,06557585 0,07887829 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06557585 0,07883947 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06557585 0,07880069 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06557585 0,07876195 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,06557585 0,07872325 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06557585 0,07868458 ! primary neural tube formation GO:0014020 61 29 0,000 0,06557585 0,07864595 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06557585 0,07860736 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06557585 0,07856881 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06557585 0,0785303 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,06557585 0,07849182 ! synaptogenesis GO:0007416 46 29 0,000 0,06557585 0,07845338 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06557585 0,07841498 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06557585 0,07837662 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06557585 0,07833829 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06557585 0,0783 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06775964 0,080868 ! phenol metabolic process GO:0018958 56 30 0,000 0,06775964 0,08082851 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,06775964 0,08078907 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06775964 0,08074966 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06775964 0,08071029 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06775964 0,08067095 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06775964 0,08063166 ! acute-phase response GO:0006953 50 30 0,000 0,06775964 0,0805924 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06775964 0,08055319 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06775964 0,08051401 ! myofibril assembly GO:0030239 50 30 0,000 0,06775964 0,08047486 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06775964 0,08043576 ! cell fate determination GO:0001709 64 30 0,000 0,06775964 0,0803967 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06775964 0,08035767 ! phospholipid transport GO:0015914 65 30 0,000 0,06775964 0,08031868 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06775964 0,08027973 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06775964 0,08024081 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06775964 0,08020194 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06775964 0,0801631 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06775964 0,0801243 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,06775964 0,08008553 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06993838 0,08262063 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06993838 0,0825807 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06993838 0,08254081 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06993838 0,08250095 ! cell junction assembly GO:0034329 85 31 0,000 0,06993838 0,08246113 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06993838 0,08242136 ! peptide transport GO:0015833 60 31 0,000 0,06993838 0,08238162 ! male gonad development GO:0008584 56 31 0,000 0,06993838 0,08234191 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06993838 0,08230225 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06993838 0,08226262 ! detection of light stimulus GO:0009583 44 31 0,000 0,06993838 0,08222304 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,06993838 0,08218349 ! natural killer cell activation GO:0030101 50 31 0,000 0,06993838 0,08214398 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06993838 0,0821045 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06993838 0,08206507 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06993838 0,08202567 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06993838 0,08198631 ! eye morphogenesis GO:0048592 65 31 0,000 0,06993838 0,08194699 ! response to heat GO:0009408 54 31 0,000 0,06993838 0,0819077 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,0721121 0,08441296 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,0721121 0,08437254 ! collagen metabolic process GO:0032963 49 32 0,000 0,0721121 0,08433215 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,0721121 0,0842918 ! spindle organization GO:0007051 50 32 0,000 0,0721121 0,08425148 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,0721121 0,08421121 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,0721121 0,08417098 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,0721121 0,08413078 ! muscle cell development GO:0055001 52 32 0,000 0,0721121 0,08409062 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,0721121 0,0840505 ! peripheral nervous system development GO:0007422 68 32 0,000 0,0721121 0,08401042 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,0721121 0,08397038 ! gene silencing GO:0016458 71 32 0,000 0,0721121 0,08393037 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,07428079 0,08641332 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,07428079 0,08637219 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,07428079 0,0863311 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,07428079 0,08629005 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,07428079 0,08624904 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,07428079 0,08620806 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,07428079 0,08616713 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,07428079 0,08612623 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07644448 0,08859291 ! glial cell differentiation GO:0010001 67 34 0,000 0,07644448 0,08855091 ! post-embryonic development GO:0009791 76 34 0,000 0,07644448 0,08850894 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,07644448 0,08846701 ! cholesterol transport GO:0030301 62 34 0,000 0,07644448 0,08842513 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07644448 0,08838328 ! spliceosome assembly GO:0000245 75 34 0,000 0,07644448 0,08834147 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07644448 0,0882997 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,07644448 0,08825797 ! cell fate specification GO:0001708 56 34 0,000 0,07644448 0,08821628 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,07644448 0,08817463 ! adult locomotory behavior GO:0008344 62 34 0,000 0,07644448 0,08813302 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,07860317 0,09057903 ! negative regulation of secretion GO:0051048 68 35 0,000 0,07860317 0,09053633 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,07860317 0,09049366 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,07860317 0,09045103 ! membrane docking GO:0022406 69 35 0,000 0,07860317 0,09040845 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,07860317 0,0903659 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,07860317 0,0903234 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,07860317 0,09028093 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,07860317 0,09023851 ! ceramide metabolic process GO:0006672 72 35 0,000 0,07860317 0,09019612 ! telencephalon development GO:0021537 81 35 0,000 0,07860317 0,09015378 ! sterol transport GO:0015918 63 35 0,000 0,07860317 0,09011147 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,07860317 0,09006921 ! placenta development GO:0001890 53 35 0,000 0,07860317 0,09002698 ! vesicle localization GO:0051648 70 35 0,000 0,07860317 0,08998479 ! regulation of muscle development GO:0048634 82 36 0,000 0,08075688 0,09240705 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,08075688 0,09236379 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,08075688 0,09232057 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,08075688 0,09227738 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,08075688 0,09223424 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,08075688 0,09219114 ! protein targeting to membrane GO:0006612 75 36 0,000 0,08075688 0,09214808 ! regulation of proteolysis GO:0030162 77 36 0,000 0,08075688 0,09210506 ! aerobic respiration GO:0009060 56 36 0,000 0,08075688 0,09206209 ! cytokine production GO:0001816 68 36 0,000 0,08075688 0,09201915 ! embryonic organ development GO:0048568 67 36 0,000 0,08075688 0,09197625 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,08075688 0,09193339 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,08075688 0,09189057 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,08290561 0,09429162 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,08290561 0,09424774 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,08290561 0,09420391 ! sister chromatid segregation GO:0000819 65 37 0,000 0,08290561 0,09416011 ! actomyosin structure organization GO:0031032 68 37 0,000 0,08290561 0,09411636 ! cell junction organization GO:0034330 96 37 0,000 0,08290561 0,09407264 ! tissue remodeling GO:0048771 78 37 0,000 0,08290561 0,09402897 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,08290561 0,09398534 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,08290561 0,09394174 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,08290561 0,09389819 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,08290561 0,09385468 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,08290561 0,09381121 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,08504938 0,09619242 ! meiosis I GO:0007127 74 38 0,000 0,08504938 0,09614791 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,08504938 0,09610344 ! organic anion transport GO:0015711 82 38 0,000 0,08504938 0,09605901 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,08504938 0,09601462 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,08504938 0,09597027 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,08504938 0,09592596 GO:0006639|acylglycerol metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,08504938 0,09588169 ! spermatid development GO:0007286 69 38 0,000 0,08504938 0,09583747 ! pigment metabolic process GO:0042440 87 38 0,000 0,08504938 0,09579328 ! neural tube formation GO:0001841 79 38 0,000 0,08504938 0,09574914 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,0871882 0,09811182 ! negative regulation of binding GO:0051100 71 39 0,000 0,0871882 0,09806665 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,0871882 0,09802152 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,0871882 0,09797643 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,0871882 0,09793139 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,08932208 0,10028209 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,08932208 0,10023603 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,08932208 0,10019001 ! learning GO:0007612 82 40 0,000 0,08932208 0,10014403 ! nucleus organization GO:0006997 73 40 0,000 0,08932208 0,10009809 ! lipid homeostasis GO:0055088 75 40 0,000 0,08932208 0,10005219 ! mismatch repair GO:0006298 58 40 0,000 0,08932208 0,10000634 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,08932208 0,09996053 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,08932208 0,09991476 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,08932208 0,09986903 ! RNA export from nucleus GO:0006405 61 41 0,000 0,09145103 0,10220259 ! mRNA catabolic process GO:0006402 79 41 0,000 0,09145103 0,10215586 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,09145103 0,10210917 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,09145103 0,10206252 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,09145103 0,10201592 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,09145103 0,10196936 ! gliogenesis GO:0042063 91 41 0,000 0,09145103 0,10192284 ! feeding behavior GO:0007631 69 41 0,000 0,09145103 0,10187636 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,09145103 0,10182993 ! mesenchymal cell development GO:0014031 94 41 0,000 0,09145103 0,10178353 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,09145103 0,10173719 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,09145103 0,10169088 ! spermatid differentiation GO:0048515 73 41 0,000 0,09145103 0,10164461 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,09145103 0,10159839 ! RNA modification GO:0009451 64 41 0,000 0,09145103 0,10155221 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,09357506 0,10386364 ! ear morphogenesis GO:0042471 64 42 0,000 0,09357506 0,10381647 ! organic ether metabolic process GO:0018904 59 42 0,000 0,09357506 0,10376935 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,09357506 0,10372227 ! regulation of protein secretion GO:0050708 77 42 0,000 0,09357506 0,10367523 ! cytokinesis GO:0000910 84 42 0,000 0,09357506 0,10362823 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,09357506 0,10358127 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,09569419 0,10587903 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,09569419 0,1058311 ! regulation of tube size GO:0035150 76 43 0,000 0,09569419 0,10578321 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,09569419 0,10573537 ! glucose transport GO:0015758 66 43 0,000 0,09569419 0,10568757 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,09569419 0,10563981 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,09569419 0,1055921 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,09569419 0,10554443 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,09569419 0,1054968 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,09569419 0,10544921 ! ion transmembrane transport GO:0034220 79 43 0,000 0,09569419 0,10540167 ! neuron migration GO:0001764 85 43 0,000 0,09569419 0,10535417 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,09569419 0,10530671 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09780842 0,10758486 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09780842 0,10753644 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09780842 0,10748807 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,09780842 0,10743974 ! hexose transport GO:0008645 68 44 0,000 0,09780842 0,10739145 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,09780842 0,1073432 ! striated muscle contraction GO:0006941 85 44 0,000 0,09780842 0,107295 ! phagocytosis GO:0006909 105 44 0,000 0,09780842 0,10724685 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09780842 0,10719873 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,09991777 0,10946149 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,09991777 0,10941242 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,09991777 0,1093634 ! biopolymer methylation GO:0043414 91 45 0,000 0,09991777 0,10931443 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,09991777 0,10926549 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,09991777 0,10921661 ! maintenance of location in cell GO:0051651 101 45 0,000 0,09991777 0,10916776 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,10202225 0,11141723 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,10202225 0,11136745 ! pigmentation GO:0043473 103 46 0,000 0,10202225 0,11131771 ! cell growth GO:0016049 90 46 0,000 0,10202225 0,11126801 ! neural tube development GO:0021915 91 47 0,000 0,10412186 0,11350723 ! positive regulation of defense response GO:0031349 88 48 0,000 0,10621663 0,11573917 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,10621663 0,11568757 ! cellular component disassembly GO:0022411 89 48 0,000 0,10621663 0,11563602 ! endosome transport GO:0016197 127 48 0,000 0,10621663 0,11558451 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,10621663 0,11553305 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,10621663 0,11548163 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,10621663 0,11543026 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,10621663 0,11537893 ! methylation GO:0032259 97 48 0,000 0,10621663 0,11532765 ! response to calcium ion GO:0051592 94 49 0,000 0,10830655 0,11754461 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10830655 0,11749241 ! protein homooligomerization GO:0051260 84 49 0,000 0,10830655 0,11744026 ! regulation of action potential GO:0001508 102 50 0,000 0,11039165 0,1196481 ! regulation of ion transport GO:0043269 86 50 0,000 0,11039165 0,11959504 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,11039165 0,11954202 ! endocrine system development GO:0035270 109 50 0,000 0,11039165 0,11948906 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,11039165 0,11943614 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,11039165 0,11938327 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,11039165 0,11933045 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,11039165 0,11927767 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,11039165 0,11922494 ! viral infectious cycle GO:0019058 104 51 0,000 0,11247193 0,121418 ! peptide metabolic process GO:0006518 80 51 0,000 0,11247193 0,12136437 ! response to temperature stimulus GO:0009266 84 51 0,000 0,11247193 0,12131079 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,11247193 0,12125725 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,11247193 0,12120376 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,11454741 0,12338594 ! Notch signaling pathway GO:0007219 111 52 0,000 0,11454741 0,12333156 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,11454741 0,12327723 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,11454741 0,12322295 ! excretion GO:0007588 87 52 0,000 0,11454741 0,12316871 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,11454741 0,12311453 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,11454741 0,12306039 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,11454741 0,12300629 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,11454741 0,12295225 ! amino acid activation GO:0043038 98 52 0,000 0,11454741 0,12289825 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,11661809 0,12506496 ! inner ear development GO:0048839 89 53 0,000 0,11661809 0,12501009 ! chromatin remodeling GO:0006338 122 53 0,000 0,11661809 0,12495526 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,11661809 0,12490048 ! vesicle organization GO:0016050 127 53 0,000 0,11661809 0,12484574 ! synapse organization GO:0050808 102 53 0,000 0,11661809 0,12479106 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,11868398 0,12694613 ! regulation of translational initiation GO:0006446 87 54 0,000 0,11868398 0,12689058 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11868398 0,12683507 ! neuromuscular process GO:0050905 107 54 0,000 0,11868398 0,12677961 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,11868398 0,1267242 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,11868398 0,12666884 ! membrane fusion GO:0006944 122 54 0,000 0,11868398 0,12661352 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11868398 0,12655826 ! regulation of cell shape GO:0008360 142 54 0,000 0,11868398 0,12650304 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,11868398 0,12644787 ! RNA catabolic process GO:0006401 103 55 0,000 0,12074511 0,12858775 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,12074511 0,12853172 ! cell recognition GO:0008037 98 55 0,000 0,12074511 0,12847574 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,12074511 0,12841981 ! cell maturation GO:0048469 107 55 0,000 0,12074511 0,12836392 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,12074511 0,12830809 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,12280147 0,13043651 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,12280147 0,13037983 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,12280147 0,13032319 ! RNA elongation GO:0006354 90 56 0,000 0,12280147 0,1302666 ! chloride transport GO:0006821 102 57 0,000 0,12485307 0,13238544 ! muscle fiber development GO:0048747 131 57 0,000 0,12485307 0,13232801 ! regulation of actin filament length GO:0030832 118 58 0,000 0,12689994 0,1344391 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,12689994 0,13438082 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,12689994 0,1343226 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,12689994 0,13426443 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,12689994 0,1342063 ! maintenance of location GO:0051235 124 58 0,000 0,12689994 0,13414823 ! nuclear export GO:0051168 110 59 0,000 0,12894208 0,13624805 ! establishment of organelle localization GO:0051656 122 59 0,000 0,12894208 0,13618915 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,1309795 0,13828129 ! DNA catabolic process GO:0006308 94 60 0,000 0,1309795 0,13822156 ! regulation of endocytosis GO:0030100 104 60 0,000 0,1309795 0,13816188 ! adult behavior GO:0030534 104 60 0,000 0,1309795 0,13810225 ! regulation of cellular component size GO:0032535 125 61 0,000 0,13301221 0,140185 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,13301221 0,14012455 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,13301221 0,14006415 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,13301221 0,1400038 ! regulation of heart contraction GO:0008016 123 61 0,000 0,13301221 0,13994351 ! proton transport GO:0015992 117 61 0,000 0,13301221 0,13988327 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,13301221 0,13982308 ! tRNA processing GO:0008033 102 62 0,000 0,13504022 0,14189388 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,13504022 0,14183287 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,13706355 0,14389611 ! regulation of mitosis GO:0007088 112 63 0,000 0,13706355 0,1438343 GO:0051783|regulation of nuclear division, ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,13706355 0,14377254 ! hydrogen transport GO:0006818 121 64 0,000 0,1390822 0,14582739 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,1390822 0,14576483 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,14109618 0,14781217 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,14109618 0,14774881 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,14109618 0,14768551 ! ear development GO:0043583 114 66 0,000 0,14310551 0,14972453 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,14310551 0,14966043 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,14310551 0,14959639 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,1451102 0,15162712 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,1451102 0,1515623 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,1451102 0,15149753 ! secondary metabolic process GO:0019748 125 67 0,000 0,1451102 0,15143281 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,1451102 0,15136815 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,14711025 0,15338896 ! extracellular matrix organization GO:0030198 146 68 0,000 0,14711025 0,15332353 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,14711025 0,15325814 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,14711025 0,15319281 ! adaptive immune response GO:0002250 126 68 0,000 0,14711025 0,15312754 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,14711025 0,15306233 ! cell projection assembly GO:0030031 138 68 0,000 0,14711025 0,15299717 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,14910568 0,15500646 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,14910568 0,15494053 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,14910568 0,15487465 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,14910568 0,15480883 ! developmental maturation GO:0021700 128 69 0,000 0,14910568 0,15474307 ! single fertilization GO:0007338 83 69 0,000 0,14910568 0,15467736 ! cell redox homeostasis GO:0045454 114 70 0,000 0,1510965 0,15667604 ! germ cell development GO:0007281 133 70 0,000 0,1510965 0,15660956 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,1510965 0,15654315 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,15308271 0,15853373 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,15308271 0,15846655 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,15308271 0,15839944 ! carbohydrate transport GO:0008643 114 72 0,000 0,15506434 0,16038195 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,15506434 0,16031408 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,15506434 0,16024627 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,15506434 0,16017851 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,15506434 0,16011081 ! humoral immune response GO:0006959 115 73 0,000 0,15704138 0,16208369 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,15704138 0,16201524 ! acute inflammatory response GO:0002526 118 74 0,000 0,15901385 0,16398094 ! amino acid transport GO:0006865 148 74 0,000 0,15901385 0,16391175 ! organelle localization GO:0051640 155 74 0,000 0,15901385 0,16384261 ! transition metal ion transport GO:0000041 143 75 0,000 0,16098176 0,16580036 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,16098176 0,16573049 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,16098176 0,16566068 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,16294513 0,1676105 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,16294513 0,16753996 ! learning or memory GO:0007611 161 76 0,000 0,16294513 0,16746948 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,16294513 0,16739905 ! regulation of blood pressure GO:0008217 134 76 0,000 0,16294513 0,16732869 ! amine catabolic process GO:0009310 136 77 0,000 0,16490395 0,16926905 ! neurotransmitter transport GO:0006836 142 77 0,000 0,16490395 0,16919796 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,16490395 0,16912693 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,16490395 0,16905596 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,16685824 0,17098771 ! antigen processing and presentation GO:0019882 117 78 0,000 0,16685824 0,17091601 ! fertilization GO:0009566 99 78 0,000 0,16685824 0,17084438 ! blood coagulation GO:0007596 151 79 0,000 0,16880802 0,17276833 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,16880802 0,17269598 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,16880802 0,17262369 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,16880802 0,17255146 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,16880802 0,1724793 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,16880802 0,17240719 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,17075329 0,17432106 ! meiosis GO:0007126 143 81 0,000 0,17269406 0,17622873 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,17269406 0,17615515 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,17269406 0,17608163 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,17463034 0,17798161 ! meiotic cell cycle GO:0051321 144 82 0,000 0,17463034 0,17790739 ! exocytosis GO:0006887 153 83 0,000 0,17656215 0,17980047 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,17656215 0,17972555 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,17656215 0,1796507 ! inorganic anion transport GO:0015698 156 83 0,000 0,17656215 0,17957591 ! response to metal ion GO:0010038 158 84 0,000 0,17848949 0,1814606 ! response to nutrient GO:0007584 135 84 0,000 0,17848949 0,18138511 ! digestion GO:0007586 130 84 0,000 0,17848949 0,18130969 ! regulation of ligase activity GO:0051340 147 84 0,000 0,17848949 0,18123434 ! hemostasis GO:0007599 165 85 0,000 0,18041237 0,18311068 ! negative regulation of transport GO:0051051 164 85 0,000 0,18041237 0,18303464 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,18041237 0,18295866 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,18041237 0,18288274 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,1842448 0,18669019 ! nucleosome assembly GO:0006334 126 87 0,000 0,1842448 0,18661279 ! cellular respiration GO:0045333 143 88 0,000 0,18615437 0,18846876 ! sensory perception of smell GO:0007608 117 88 0,000 0,18615437 0,18839069 ! chromatin assembly GO:0031497 128 88 0,000 0,18615437 0,18831268 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,18615437 0,18823474 ! tube morphogenesis GO:0035239 194 89 0,000 0,18805953 0,19008251 ! cellular defense response GO:0006968 123 89 0,000 0,18805953 0,1900039 ! regulation of neurological system process GO:0031644 175 89 0,000 0,18805953 0,18992535 ! response to inorganic substance GO:0010035 173 90 0,000 0,18996028 0,19176568 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,18996028 0,19168647 ! response to unfolded protein GO:0006986 139 90 0,000 0,18996028 0,19160733 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,18996028 0,19152825 ! gland development GO:0048732 220 91 0,000 0,19185663 0,19336046 ! defense response to bacterium GO:0042742 112 91 0,000 0,19185663 0,19328072 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,1937486 0,19510627 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,19563619 0,19692592 GO:0010498|proteasomal protein catabolic process, ! vitamin metabolic process GO:0006766 153 93 0,000 0,19563619 0,19684481 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,19751941 0,19865785 ! female pregnancy GO:0007565 166 94 0,000 0,19751941 0,1985761 ! sterol metabolic process GO:0016125 166 94 0,000 0,19751941 0,19849441 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,19751941 0,1984128 ! regulation of membrane potential GO:0042391 179 94 0,000 0,19751941 0,19833125 ! regulation of defense response GO:0031347 171 95 0,000 0,19939828 0,20013558 ! nucleosome organization GO:0034728 143 95 0,000 0,19939828 0,20005339 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,19939828 0,19997126 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,19939828 0,19988921 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,19939828 0,19980722 ! response to protein stimulus GO:0051789 158 96 0,000 0,2012728 0,20160289 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,20314299 0,20339275 ! transcription initiation GO:0006352 171 97 0,000 0,20314299 0,20330943 ! forebrain development GO:0030900 210 98 0,000 0,20500885 0,2050928 ! hormone metabolic process GO:0042445 171 100 0,000 0,20872763 0,20872763