pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6851-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! response to endoplasmic reticulum stress GO:0034976 13 13 3,000 4,89E-07 9,013E-04 ! peptidyl-amino acid modification GO:0018193 61 59 5,000 5,803E-07 5,347E-04 ! insulin receptor signaling pathway GO:0008286 17 15 3,000 9,265E-07 5,692E-04 ! ER-nuclear signaling pathway GO:0006984 15 15 3,000 9,265E-07 4,269E-04 ! nucleus localization GO:0051647 5 5 2,000 1,422E-06 5,24E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 3,000 2,591E-06 7,958E-04 ! ER overload response GO:0006983 6 6 2,000 2,833E-06 7,458E-04 ! peptidyl-tyrosine modification GO:0018212 21 20 3,000 3,226E-06 7,432E-04 ! cellular response to insulin stimulus GO:0032869 23 21 3,000 3,97E-06 8,129E-04 ! cellular response to hormone stimulus GO:0032870 48 46 4,000 3,972E-06 7,32E-04 ! leukocyte differentiation GO:0002521 50 49 4,000 5,461E-06 9,15E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 5,461E-06 8,388E-04 ! positive regulation of transferase activity GO:0051347 91 88 5,000 6,236E-06 8,841E-04 GO:0033674|positive regulation of kinase activity, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 2,000 7,873E-06 1,036E-03 ! regulation of gene-specific transcription GO:0032583 25 25 3,000 8,262E-06 1,015E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 8,262E-06 9,517E-04 ! response to insulin stimulus GO:0032868 28 26 3,000 9,727E-06 1,055E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 1,137E-05 1,165E-03 ! hemopoiesis GO:0030097 104 100 5,000 1,309E-05 1,27E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 1,322E-05 1,218E-03 ! epithelial to mesenchymal transition GO:0001837 10 10 2,000 1,675E-05 1,47E-03 ! establishment of organelle localization GO:0051656 31 30 3,000 1,756E-05 1,471E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 2,008E-05 1,609E-03 ! myeloid leukocyte differentiation GO:0002573 12 11 2,000 2,294E-05 1,762E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 2,294E-05 1,691E-03 GO:0032388|positive regulation of intracellular transport, ! regulation of MAP kinase activity GO:0043405 67 66 4,000 2,396E-05 1,698E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 2,926E-05 1,997E-03 ! regulation of cell migration GO:0030334 71 71 4,000 3,423E-05 2,253E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 3,688E-05 2,344E-03 ! protein tetramerization GO:0051262 13 13 2,000 3,947E-05 2,425E-03 ! protein oligomerization GO:0051259 39 39 3,000 5,091E-05 3,027E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 5,091E-05 2,932E-03 ! organelle localization GO:0051640 41 40 3,000 5,635E-05 3,147E-03 ! regulation of locomotion GO:0040012 79 79 4,000 5,744E-05 3,114E-03 ! regulation of cell motion GO:0051270 79 79 4,000 5,744E-05 3,025E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 2,000 7,642E-05 3,912E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 7,642E-05 3,807E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 8,638E-05 4,189E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 9,246E-05 4,369E-03 ! meiosis I GO:0007127 18 18 2,000 1,105E-04 5,093E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 1,105E-04 4,969E-03 ! regulation of protein transport GO:0051223 53 53 3,000 1,718E-04 7,537E-03 GO:0070201|regulation of establishment of protein localization, ! response to hormone stimulus GO:0009725 102 100 4,000 1,768E-04 7,579E-03 ! microtubule cytoskeleton organization GO:0000226 55 55 3,000 1,985E-04 8,315E-03 ! spindle organization GO:0007051 22 22 2,000 2,055E-04 8,418E-03 ! regulation of protein localization GO:0032880 58 57 3,000 2,282E-04 9,141E-03 ! positive regulation of growth GO:0045927 23 23 2,000 2,355E-04 9,235E-03 ! T cell differentiation GO:0030217 24 24 2,000 2,681E-04 0,0102957 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 2,786E-04 0,01047837 ! filopodium assembly GO:0046847 7 5 1,000 2,786E-04 0,0102688 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 2,786E-04 0,01006745 GO:0043489|RNA stabilization, ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 2,786E-04 9,874E-03 ! endocrine pancreas development GO:0031018 5 5 1,000 2,786E-04 9,688E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 2,786E-04 9,508E-03 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 2,786E-04 9,335E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 2,786E-04 9,169E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 2,786E-04 9,008E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 2,786E-04 8,852E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 2,786E-04 8,702E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 2,786E-04 8,557E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 3,419E-04 0,0103303 ! mesenchymal cell development GO:0014031 29 27 2,000 3,832E-04 0,01139187 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 4,165E-04 0,01218333 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 4,165E-04 0,01199297 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 4,165E-04 0,01180846 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 4,165E-04 0,01162954 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 4,165E-04 0,01145597 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 1,000 4,165E-04 0,0112875 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 4,165E-04 0,01112391 ! focal adhesion formation GO:0048041 7 6 1,000 4,165E-04 0,010965 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,165E-04 0,01081056 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 4,165E-04 0,01066041 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 4,165E-04 0,01051438 ! regulation of bone resorption GO:0045124 6 6 1,000 4,165E-04 0,01037229 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 4,165E-04 0,010234 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,165E-04 0,01009934 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 4,165E-04 9,968E-03 ! nitric oxide metabolic process GO:0046209 6 6 1,000 4,165E-04 9,84E-03 GO:0006809|nitric oxide biosynthetic process, ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 4,165E-04 9,716E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 4,165E-04 9,594E-03 ! positive regulation of protein transport GO:0051222 29 29 2,000 4,752E-04 0,01081256 ! regulation of DNA replication GO:0006275 32 31 2,000 5,803E-04 0,01304205 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 5,811E-04 0,01290276 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 5,811E-04 0,01274915 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 5,811E-04 0,01259916 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 5,811E-04 0,01245266 ! regulation of mRNA processing GO:0050684 7 7 1,000 5,811E-04 0,01230953 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 5,811E-04 0,01216965 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 5,811E-04 0,01203291 ! regulation of intracellular pH GO:0051453 7 7 1,000 5,811E-04 0,01189921 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 5,811E-04 0,01176845 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 5,811E-04 0,01164053 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 5,811E-04 0,01151536 ! regulation of mRNA stability GO:0043488 7 7 1,000 5,811E-04 0,01139286 ! negative regulation of T cell activation GO:0050868 7 7 1,000 5,811E-04 0,01127294 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 7,239E-04 0,01389805 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 7,721E-04 0,01467081 ! pancreas development GO:0031016 8 8 1,000 7,721E-04 0,01452111 ! phosphagen metabolic process GO:0006599 8 8 1,000 7,721E-04 0,01437443 GO:0006600|creatine metabolic process, ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 7,721E-04 0,01423069 ! sex determination GO:0007530 8 8 1,000 7,721E-04 0,01408979 ! peptidyl-serine modification GO:0018209 8 8 1,000 7,721E-04 0,01395165 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 7,721E-04 0,0138162 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 7,721E-04 0,01368335 ! regulation of RNA stability GO:0043487 8 8 1,000 7,721E-04 0,01355304 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 7,721E-04 0,01342518 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 7,721E-04 0,01329971 ! MAPKKK cascade GO:0000165 82 81 3,000 8,765E-04 0,0149569 ! meiosis GO:0007126 37 37 2,000 9,81E-04 0,01658764 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 2,000 9,81E-04 0,01643684 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 9,81E-04 0,01628876 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 9,894E-04 0,01628093 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 9,894E-04 0,01613686 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 9,894E-04 0,0159953 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 9,894E-04 0,01585621 ! pigmentation during development GO:0048066 9 9 1,000 9,894E-04 0,01571952 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 9,894E-04 0,01558517 ! regulation of cellular pH GO:0030641 9 9 1,000 9,894E-04 0,01545309 ! histone acetylation GO:0016573 9 9 1,000 9,894E-04 0,01532323 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 9,894E-04 0,01519554 ! regulation of leukocyte migration GO:0002685 9 9 1,000 9,894E-04 0,01506996 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 9,894E-04 0,01494643 ! regulation of cellular localization GO:0060341 86 85 3,000 1,05E-03 0,01573968 ! meiotic cell cycle GO:0051321 38 38 2,000 1,061E-03 0,01577245 ! activation of MAPK activity GO:0000187 39 39 2,000 1,145E-03 0,01688758 ! respiratory tube development GO:0030323 40 39 2,000 1,145E-03 0,01675355 ! response to unfolded protein GO:0006986 39 39 2,000 1,145E-03 0,01662163 ! respiratory system development GO:0060541 40 39 2,000 1,145E-03 0,01649178 ! lymphocyte differentiation GO:0030098 39 39 2,000 1,145E-03 0,01636393 ! heart development GO:0007507 90 87 3,000 1,146E-03 0,01624633 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,233E-03 0,01734058 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,233E-03 0,01720921 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,233E-03 0,01707982 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,233E-03 0,01695235 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,233E-03 0,01682678 ! cellular response to unfolded protein GO:0034620 10 10 1,000 1,233E-03 0,01670306 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 10 10 1,000 1,233E-03 0,01658114 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,233E-03 0,01646098 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,233E-03 0,01634256 ! myeloid cell differentiation GO:0030099 42 40 2,000 1,234E-03 0,01624061 ! regulation of caspase activity GO:0043281 41 41 2,000 1,326E-03 0,0173343 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 1,423E-03 0,01846787 ! response to protein stimulus GO:0051789 42 42 2,000 1,423E-03 0,01833873 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 1,501E-03 0,01921544 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,501E-03 0,01908292 ! cellular response to starvation GO:0009267 11 11 1,000 1,501E-03 0,01895222 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 1,501E-03 0,01882329 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 1,501E-03 0,01869611 ! G1/S transition checkpoint GO:0031575 12 11 1,000 1,501E-03 0,01857063 ! interaction with host GO:0051701 11 11 1,000 1,501E-03 0,01844683 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,501E-03 0,01832466 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,501E-03 0,01820411 ! protein import into nucleus GO:0006606 44 44 2,000 1,629E-03 0,01962827 ! nuclear import GO:0051170 45 45 2,000 1,739E-03 0,02081669 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 1,739E-03 0,02068239 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 1,739E-03 0,02054981 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 1,783E-03 0,02093039 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 1,796E-03 0,02094428 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 1,796E-03 0,02081256 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 1,000 1,796E-03 0,02068248 ! xenobiotic metabolic process GO:0006805 12 12 1,000 1,796E-03 0,02055402 ! regulation of chromosome organization GO:0033044 12 12 1,000 1,796E-03 0,02042714 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 1,796E-03 0,02030182 ! somitogenesis GO:0001756 13 12 1,000 1,796E-03 0,02017803 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,796E-03 0,02005574 ! negative regulation of translation GO:0017148 12 12 1,000 1,796E-03 0,01993492 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,796E-03 0,01981555 ! regulation of peptidase activity GO:0052547 46 46 2,000 1,854E-03 0,02033802 ! regulation of catabolic process GO:0009894 48 47 2,000 1,973E-03 0,02151655 ! protein localization in nucleus GO:0034504 48 48 2,000 2,097E-03 0,0227319 ! positive regulation of DNA replication GO:0045740 14 13 1,000 2,115E-03 0,02279324 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 2,115E-03 0,02266072 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 2,115E-03 0,02252973 ! vasculogenesis GO:0001570 13 13 1,000 2,115E-03 0,02240025 ! mitochondrial membrane organization GO:0007006 13 13 1,000 2,115E-03 0,02227225 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 2,115E-03 0,0221457 ! negative regulation of DNA replication GO:0008156 13 13 1,000 2,115E-03 0,02202059 ! actin filament bundle formation GO:0051017 13 13 1,000 2,115E-03 0,02189687 ! cell aging GO:0007569 13 13 1,000 2,115E-03 0,02177455 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 2,115E-03 0,02165358 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,115E-03 0,02153394 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,115E-03 0,02141562 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,115E-03 0,0212986 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,115E-03 0,02118285 ! alkene biosynthetic process GO:0043450 13 13 1,000 2,115E-03 0,02106834 GO:0019370|leukotriene biosynthetic process, ! tissue homeostasis GO:0001894 13 13 1,000 2,115E-03 0,02095507 GO:0048871|multicellular organismal homeostasis, ! cell cycle arrest GO:0007050 49 49 2,000 2,225E-03 0,02193199 ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,225E-03 0,02181533 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 2,000 2,359E-03 0,02299995 ! T cell activation GO:0042110 51 50 2,000 2,359E-03 0,0228789 ! protein amino acid acylation GO:0043543 14 14 1,000 2,459E-03 0,02372711 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 2,459E-03 0,02360354 ! regulation of behavior GO:0050795 14 14 1,000 2,459E-03 0,02348124 ! base-excision repair GO:0006284 14 14 1,000 2,459E-03 0,0233602 ! leukotriene metabolic process GO:0006691 14 14 1,000 2,459E-03 0,0232404 ! response to hypoxia GO:0001666 53 53 2,000 2,788E-03 0,02621604 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 2,828E-03 0,02645391 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 2,828E-03 0,0263203 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 2,828E-03 0,02618804 ! response to starvation GO:0042594 15 15 1,000 2,828E-03 0,0260571 ! response to ionizing radiation GO:0010212 16 15 1,000 2,828E-03 0,02592746 ! cellular alkene metabolic process GO:0043449 15 15 1,000 2,828E-03 0,02579911 ! negative regulation of cell activation GO:0050866 15 15 1,000 2,828E-03 0,02567202 ! protein homooligomerization GO:0051260 15 15 1,000 2,828E-03 0,02554617 ! response to oxygen levels GO:0070482 55 54 2,000 2,941E-03 0,02644179 ! response to virus GO:0009615 54 54 2,000 2,941E-03 0,02631343 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 3,221E-03 0,0286753 ! positive regulation of mitosis GO:0045840 16 16 1,000 3,221E-03 0,02853744 GO:0051785|positive regulation of nuclear division, ! segmentation GO:0035282 17 16 1,000 3,221E-03 0,02840089 ! cellular response to nutrient levels GO:0031669 16 16 1,000 3,221E-03 0,02826565 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 3,221E-03 0,02813169 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 3,638E-03 0,03162502 ! glucose transport GO:0015758 17 17 1,000 3,638E-03 0,03147655 ! cell junction assembly GO:0034329 18 17 1,000 3,638E-03 0,03132946 ! tissue remodeling GO:0048771 17 17 1,000 3,638E-03 0,03118375 ! response to toxin GO:0009636 18 17 1,000 3,638E-03 0,03103938 ! pigmentation GO:0043473 17 17 1,000 3,638E-03 0,03089634 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 3,638E-03 0,03075461 ! myelination GO:0042552 17 17 1,000 3,638E-03 0,03061418 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 3,638E-03 0,03047502 ! negative regulation of cell development GO:0010721 18 17 1,000 3,638E-03 0,03033713 GO:0050768|negative regulation of neurogenesis, ! protein localization in organelle GO:0033365 59 59 2,000 3,784E-03 0,03141716 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,079E-03 0,03370898 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 4,079E-03 0,0335585 ! icosanoid biosynthetic process GO:0046456 18 18 1,000 4,079E-03 0,03340935 ! hexose transport GO:0008645 18 18 1,000 4,079E-03 0,03326152 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 18 18 1,000 4,079E-03 0,03311499 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 4,079E-03 0,03296975 ! ensheathment of neurons GO:0007272 18 18 1,000 4,079E-03 0,03282578 GO:0008366|axon ensheathment, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 4,079E-03 0,03268306 ! protein import GO:0017038 62 62 2,000 4,354E-03 0,0347396 ! DNA damage checkpoint GO:0000077 19 19 1,000 4,543E-03 0,036091 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 4,543E-03 0,03593611 ! regulation of pH GO:0006885 19 19 1,000 4,543E-03 0,03578253 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 4,543E-03 0,03563027 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 4,543E-03 0,03547929 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 4,543E-03 0,03532959 ! peripheral nervous system development GO:0007422 19 19 1,000 4,543E-03 0,03518115 ! regulation of cell shape GO:0008360 21 19 1,000 4,543E-03 0,03503394 ! response to heat GO:0009408 19 19 1,000 4,543E-03 0,03488797 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 4,555E-03 0,03483446 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 4,762E-03 0,0362628 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 4,974E-03 0,03772182 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 5,031E-03 0,03800028 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 5,031E-03 0,03784518 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 1,000 5,031E-03 0,03769134 ! striated muscle tissue development GO:0014706 69 67 2,000 5,415E-03 0,04040194 ! Ras protein signal transduction GO:0007265 69 67 2,000 5,415E-03 0,04023902 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 5,542E-03 0,04101812 ! mammary gland development GO:0030879 23 21 1,000 5,542E-03 0,04085404 ! DNA integrity checkpoint GO:0031570 21 21 1,000 5,542E-03 0,04069128 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 5,542E-03 0,04052981 ! regulation of action potential in neuron GO:0019228 21 21 1,000 5,542E-03 0,04036961 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 5,542E-03 0,04021067 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 5,542E-03 0,04005298 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 5,542E-03 0,03989653 ! negative regulation of protein transport GO:0051224 21 21 1,000 5,542E-03 0,03974129 ! response to radiation GO:0009314 70 68 2,000 5,644E-03 0,0403159 ! regulation of translation GO:0006417 69 69 2,000 5,879E-03 0,04183146 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 5,879E-03 0,04167057 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 6,075E-03 0,04290031 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 6,075E-03 0,04273657 ! sister chromatid segregation GO:0000819 22 22 1,000 6,075E-03 0,04257407 ! cellular amide metabolic process GO:0043603 22 22 1,000 6,075E-03 0,04241281 ! cell junction organization GO:0034330 23 22 1,000 6,075E-03 0,04225276 ! cytokinesis GO:0000910 23 22 1,000 6,075E-03 0,04209391 ! positive regulation of transport GO:0051050 71 70 2,000 6,119E-03 0,04223929 ! muscle tissue development GO:0060537 72 70 2,000 6,119E-03 0,04208168 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 6,632E-03 0,04543503 ! endocrine system development GO:0035270 23 23 1,000 6,632E-03 0,04526676 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 6,632E-03 0,04509972 ! cell projection assembly GO:0030031 25 23 1,000 6,632E-03 0,04493391 ! mitochondrial transport GO:0006839 24 24 1,000 7,21E-03 0,04867469 ! regulation of action potential GO:0001508 24 24 1,000 7,21E-03 0,04849705 ! glucose homeostasis GO:0042593 24 24 1,000 7,21E-03 0,04832069 GO:0033500|carbohydrate homeostasis, ! androgen receptor signaling pathway GO:0030521 24 24 1,000 7,21E-03 0,04814562 ! glucan metabolic process GO:0044042 25 24 1,000 7,21E-03 0,04797181 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of T cell proliferation GO:0042129 25 25 1,000 7,811E-03 0,05178069 ! positive regulation of DNA binding GO:0043388 26 25 1,000 7,811E-03 0,0515951 ! heart morphogenesis GO:0003007 25 25 1,000 7,811E-03 0,05141083 ! icosanoid metabolic process GO:0006690 25 25 1,000 7,811E-03 0,05122787 ! negative regulation of immune system process GO:0002683 25 25 1,000 7,811E-03 0,05104621 ! JAK-STAT cascade GO:0007259 26 25 1,000 7,811E-03 0,05086584 ! positive regulation of binding GO:0051099 27 26 1,000 8,433E-03 0,05472573 ! negative regulation of cell migration GO:0030336 26 26 1,000 8,433E-03 0,05453371 ! regulation of T cell differentiation GO:0045580 26 26 1,000 8,433E-03 0,05434303 ! double-strand break repair GO:0006302 27 26 1,000 8,433E-03 0,05415368 ! synapse organization GO:0050808 26 26 1,000 8,433E-03 0,05396565 ! nuclear transport GO:0051169 79 79 2,000 8,552E-03 0,05453989 GO:0006913|nucleocytoplasmic transport, ! energy reserve metabolic process GO:0006112 28 27 1,000 9,077E-03 0,05768611 ! learning or memory GO:0007611 28 27 1,000 9,077E-03 0,05748787 ! activation of caspase activity GO:0006919 27 27 1,000 9,077E-03 0,057291 ! tube development GO:0035295 83 81 2,000 9,16E-03 0,057616 ! lymphocyte activation GO:0046649 82 81 2,000 9,16E-03 0,05742003 ! tRNA aminoacylation for protein translation GO:0006418 28 28 1,000 9,742E-03 0,06086505 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! carbohydrate transport GO:0008643 28 28 1,000 9,742E-03 0,06065942 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 9,742E-03 0,06045518 ! histone modification GO:0016570 28 28 1,000 9,742E-03 0,06025231 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 9,742E-03 0,0600508 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01042883 0,06406776 ! viral reproductive process GO:0022415 29 29 1,000 0,01042883 0,06385491 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,01042883 0,06364347 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01042883 0,06343343 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01042883 0,06322476 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01042883 0,06301747 ! response to UV GO:0009411 29 29 1,000 0,01042883 0,06281153 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,01078715 0,06475805 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01113617 0,06663622 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01113617 0,06642057 GO:0043280|positive regulation of caspase activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01113617 0,06620631 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,01113617 0,06599343 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01113617 0,06578191 ! regulation of translational initiation GO:0006446 31 31 1,000 0,01186416 0,0698583 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01186416 0,06963582 ! B cell activation GO:0042113 31 31 1,000 0,01186416 0,06941475 ! aging GO:0007568 32 31 1,000 0,01186416 0,06919508 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01186416 0,0689768 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,01261257 0,07309741 ! muscle fiber development GO:0048747 32 32 1,000 0,01261257 0,07286826 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01261257 0,07264055 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01261257 0,07241425 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,01294859 0,07411261 ! negative regulation of cell size GO:0045792 33 33 1,000 0,01338118 0,07635146 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,01338118 0,07611581 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,01338118 0,0758816 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01338118 0,07564884 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01416976 0,07986198 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01416976 0,0796185 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,01416976 0,07937649 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01416976 0,07913596 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,01416976 0,07889688 ! viral reproduction GO:0016032 34 34 1,000 0,01416976 0,07865924 ! regulation of cell growth GO:0001558 97 96 2,000 0,01451797 0,08035022 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,01497808 0,08264849 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,01497808 0,08240178 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01497808 0,08215654 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,01497808 0,08191275 ! anti-apoptosis GO:0006916 100 99 2,000 0,01576316 0,08595119 ! regulation of mitosis GO:0007088 37 36 1,000 0,01580592 0,0859301 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01580592 0,08567736 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01580592 0,08542611 ! muscle organ development GO:0007517 102 100 2,000 0,01619128 0,08725299 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,01619128 0,08699861 ! response to other organism GO:0051707 101 100 2,000 0,01619128 0,0867457 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01665305 0,08896108 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,01665305 0,08870397 ! negative regulation of growth GO:0045926 37 37 1,000 0,01665305 0,08844834 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,01665305 0,08819418 ! adaptive immune response GO:0002250 37 37 1,000 0,01665305 0,08794147 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell-matrix adhesion GO:0007160 39 38 1,000 0,01751927 0,09225145 ! chromosome segregation GO:0007059 38 38 1,000 0,01751927 0,09198862 ! axon guidance GO:0007411 39 38 1,000 0,01751927 0,09172729 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01751927 0,09146744 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,01751927 0,09120906 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,01840434 0,09554704 ! fatty acid biosynthetic process GO:0006633 39 39 1,000 0,01840434 0,09527865 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01840434 0,09501176 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,01840434 0,09474637 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 0,01840434 0,09448245 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01930806 0,09884653 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,02023021 0,10328053 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,02117057 0,10778277 ! protein ubiquitination GO:0016567 43 42 1,000 0,02117057 0,10748585 ! mitochondrion organization GO:0007005 44 43 1,000 0,02212894 0,11204296 ! mRNA transport GO:0051028 44 44 1,000 0,02310511 0,11666496 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,02310511 0,1163462 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,02409886 0,12101961 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02409886 0,12069075 ! regulation of membrane potential GO:0042391 46 46 1,000 0,02510999 0,12541386 ! rRNA transcription GO:0009303 5 5 0,000 0,02660952 0,13254418 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02660952 0,13218692 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02660952 0,13183158 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02660952 0,13147814 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02660952 0,13112659 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02660952 0,13077692 ! reproductive cellular process GO:0048610 5 5 0,000 0,02660952 0,13042911 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02660952 0,13008315 ! prostate gland development GO:0030850 5 5 0,000 0,02660952 0,12973901 ! metencephalon development GO:0022037 5 5 0,000 0,02660952 0,12939669 ! water transport GO:0006833 5 5 0,000 0,02660952 0,12905617 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02660952 0,12871744 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02660952 0,12838049 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02660952 0,12804529 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02660952 0,12771184 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02660952 0,12738012 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02660952 0,12705012 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02660952 0,12672183 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02660952 0,12639522 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02660952 0,1260703 ! CTP metabolic process GO:0046036 5 5 0,000 0,02660952 0,12574704 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02660952 0,12542544 ! GTP metabolic process GO:0046039 5 5 0,000 0,02660952 0,12510548 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02660952 0,12478714 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02660952 0,12447042 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02660952 0,12415531 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02660952 0,12384178 ! social behavior GO:0035176 5 5 0,000 0,02660952 0,12352984 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02660952 0,12321946 ! memory GO:0007613 5 5 0,000 0,02660952 0,12291064 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02660952 0,12260337 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02660952 0,12229762 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02660952 0,1219934 ! response to lipid GO:0033993 5 5 0,000 0,02660952 0,12169069 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02660952 0,12138947 ! hippocampus development GO:0021766 6 5 0,000 0,02660952 0,12108974 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02660952 0,12079149 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02660952 0,12049471 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02660952 0,12019938 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02660952 0,11990549 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02660952 0,11961304 ! heart looping GO:0001947 5 5 0,000 0,02660952 0,11932201 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02660952 0,11903239 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02660952 0,11874418 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02660952 0,11845736 ! pH reduction GO:0045851 5 5 0,000 0,02660952 0,11817192 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02660952 0,11788785 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02660952 0,11760515 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02660952 0,11732379 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02660952 0,11704379 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02660952 0,11676511 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02660952 0,11648776 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02660952 0,11621172 ! adrenal gland development GO:0030325 5 5 0,000 0,02660952 0,11593699 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02660952 0,11566355 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02660952 0,1153914 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02660952 0,11512053 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02660952 0,11485093 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02660952 0,11458258 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02660952 0,11431549 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02660952 0,11404964 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02660952 0,11378503 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02660952 0,11352163 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02660952 0,11325946 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02660952 0,11299849 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02660952 0,11273873 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02660952 0,11248015 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02660952 0,11222276 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02660952 0,11196654 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02660952 0,11171149 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02660952 0,11145761 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02660952 0,11120487 ! response to ATP GO:0033198 5 5 0,000 0,02660952 0,11095327 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02660952 0,11070281 ! regulation of appetite GO:0032098 5 5 0,000 0,02660952 0,11045348 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02660952 0,11020527 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02660952 0,10995818 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,02660952 0,10971218 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02660952 0,10946729 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02660952 0,10922349 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02660952 0,10898077 ! receptor clustering GO:0043113 5 5 0,000 0,02660952 0,10873913 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02660952 0,10849855 ! fear response GO:0042596 5 5 0,000 0,02660952 0,10825904 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02660952 0,10802059 ! retinol metabolic process GO:0042572 5 5 0,000 0,02660952 0,10778318 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02660952 0,10754681 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02660952 0,10731148 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02660952 0,10707718 ! parturition GO:0007567 5 5 0,000 0,02660952 0,10684389 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02660952 0,10661162 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02660952 0,10638036 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02660952 0,1061501 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02660952 0,10592083 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02660952 0,10569256 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02660952 0,10546526 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02660952 0,10523894 ! response to UV-B GO:0010224 5 5 0,000 0,02660952 0,10501359 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02660952 0,1047892 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02660952 0,10456577 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02660952 0,10434329 ! interaction with symbiont GO:0051702 5 5 0,000 0,02660952 0,10412175 ! cellular extravasation GO:0045123 5 5 0,000 0,02660952 0,10390116 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02660952 0,10368149 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02660952 0,10346276 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02660952 0,10324494 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02660952 0,10302804 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02660952 0,10281205 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02660952 0,10259696 ! response to amine stimulus GO:0014075 5 5 0,000 0,02660952 0,10238277 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02660952 0,10216947 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02660952 0,10195706 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02660952 0,10174553 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02660952 0,10153488 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02660952 0,1013251 ! neuron recognition GO:0008038 5 5 0,000 0,02660952 0,10111618 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02660952 0,10090812 ! decidualization GO:0046697 5 5 0,000 0,02660952 0,10070092 ! hair follicle maturation GO:0048820 5 5 0,000 0,02660952 0,10049456 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02660952 0,10028905 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02660952 0,10008438 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02660952 0,09988054 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02660952 0,09967753 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02660952 0,09947535 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02660952 0,09927398 ! postreplication repair GO:0006301 5 5 0,000 0,02660952 0,09907343 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02660952 0,09887368 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02660952 0,09867474 ! histone methylation GO:0016571 5 5 0,000 0,02660952 0,0984766 ! DNA methylation GO:0006306 5 5 0,000 0,02660952 0,09827925 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02660952 0,09808269 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02660952 0,09788692 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02660952 0,09769192 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02660952 0,09749771 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02660952 0,09730426 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02660952 0,09711158 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02660952 0,09691966 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02660952 0,09672849 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02660952 0,09653808 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02660952 0,09634842 ! sterol catabolic process GO:0016127 5 5 0,000 0,02660952 0,0961595 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02660952 0,09597132 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02660952 0,09578388 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02660952 0,09559717 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02660952 0,09541118 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02660952 0,09522592 ! zymogen activation GO:0031638 5 5 0,000 0,02660952 0,09504137 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02660952 0,09485754 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02660952 0,09467441 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02660952 0,094492 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02660952 0,09431028 ! nucleosome positioning GO:0016584 5 5 0,000 0,02660952 0,09412926 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02660952 0,09394894 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02660952 0,0937693 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02660952 0,09359036 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02660952 0,09341209 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02660952 0,0932345 ! NADPH regeneration GO:0006740 5 5 0,000 0,02660952 0,09305758 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02660952 0,09288134 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02660952 0,09270576 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02660952 0,09253084 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02660952 0,09235658 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02660952 0,09218298 ! sarcomere organization GO:0045214 5 5 0,000 0,02660952 0,09201003 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02660952 0,09183773 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02660952 0,09166607 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02660952 0,09149505 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02660952 0,09132467 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02660952 0,09115492 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02660952 0,0909858 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02660952 0,09081731 ! spleen development GO:0048536 5 5 0,000 0,02660952 0,09064944 ! male genitalia development GO:0030539 5 5 0,000 0,02660952 0,09048219 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02660952 0,09031555 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02660952 0,09014953 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02660952 0,08998412 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02660952 0,08981932 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02660952 0,08965511 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02660952 0,08949151 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02660952 0,0893285 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02660952 0,08916608 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02660952 0,08900426 ! ATP catabolic process GO:0006200 5 5 0,000 0,02660952 0,08884302 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02660952 0,08868236 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02660952 0,08852229 ! blastocyst formation GO:0001825 5 5 0,000 0,02660952 0,08836279 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02660952 0,08820386 ! embryonic gut development GO:0048566 5 5 0,000 0,02660952 0,08804551 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02660952 0,08788772 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02660952 0,08773049 ! activation of innate immune response GO:0002218 5 5 0,000 0,02660952 0,08757383 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,02660952 0,08741773 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02660952 0,08726218 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02660952 0,08710719 ! muscle adaptation GO:0043500 5 5 0,000 0,02660952 0,08695274 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02660952 0,08679884 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02660952 0,08664549 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02660952 0,08649267 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02660952 0,0863404 ! defense response to fungus GO:0050832 5 5 0,000 0,02660952 0,08618866 ! lysogeny GO:0030069 5 5 0,000 0,02660952 0,08603745 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02660952 0,08588677 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02660952 0,08573662 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02660952 0,08558699 ! response to nicotine GO:0035094 5 5 0,000 0,02660952 0,08543789 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02660952 0,0852893 ! mitochondrion localization GO:0051646 5 5 0,000 0,02660952 0,08514123 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02660952 0,08499367 ! actin filament organization GO:0007015 50 48 1,000 0,02718358 0,08667706 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,02718358 0,08652736 ! gland development GO:0048732 51 49 1,000 0,02824564 0,08975294 ! negative regulation of transport GO:0051051 51 50 1,000 0,02932426 0,09301999 ! RNA transport GO:0050658 50 50 1,000 0,02932426 0,09286016 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! regulation of neurogenesis GO:0050767 51 50 1,000 0,02932426 0,09270088 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,02932426 0,09254214 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,02932426 0,09238395 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,03041926 0,09567012 ! RNA localization GO:0006403 52 52 1,000 0,03153043 0,09899588 ! cell fate commitment GO:0045165 52 52 1,000 0,03153043 0,09882752 ! response to light stimulus GO:0009416 53 52 1,000 0,03153043 0,09865973 ! axon extension GO:0048675 7 6 0,000 0,03184813 0,09948492 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03184813 0,09931659 ! tRNA modification GO:0006400 6 6 0,000 0,03184813 0,09914883 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03184813 0,09898163 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03184813 0,09881499 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03184813 0,09864892 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03184813 0,0984834 ! regulation of S phase GO:0033261 6 6 0,000 0,03184813 0,09831843 ! myotube differentiation GO:0014902 6 6 0,000 0,03184813 0,09815402 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03184813 0,09799016 ! bone remodeling GO:0046849 6 6 0,000 0,03184813 0,09782684 ! N-glycan processing GO:0006491 6 6 0,000 0,03184813 0,09766407 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03184813 0,09750184 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03184813 0,09734014 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03184813 0,09717898 ! RNA methylation GO:0001510 6 6 0,000 0,03184813 0,09701836 ! cartilage condensation GO:0001502 7 6 0,000 0,03184813 0,09685826 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03184813 0,09669869 ! artery development GO:0060840 6 6 0,000 0,03184813 0,09653965 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03184813 0,09638113 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03184813 0,09622312 ! androgen metabolic process GO:0008209 6 6 0,000 0,03184813 0,09606564 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03184813 0,09590867 ! limbic system development GO:0021761 7 6 0,000 0,03184813 0,09575221 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03184813 0,09559626 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03184813 0,09544082 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03184813 0,09528589 ! pathogenesis GO:0009405 6 6 0,000 0,03184813 0,09513145 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03184813 0,09497752 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03184813 0,09482408 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03184813 0,09467114 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03184813 0,09451869 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03184813 0,09436673 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03184813 0,09421526 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03184813 0,09406427 ! arginine metabolic process GO:0006525 6 6 0,000 0,03184813 0,09391377 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03184813 0,09376375 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03184813 0,0936142 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03184813 0,09346514 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03184813 0,09331654 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03184813 0,09316842 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03184813 0,09302077 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03184813 0,09287358 ! V(D)J recombination GO:0033151 6 6 0,000 0,03184813 0,09272687 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03184813 0,09258061 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03184813 0,09243481 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03184813 0,09228947 ! regulation of heart rate GO:0002027 6 6 0,000 0,03184813 0,09214459 ! lipid digestion GO:0044241 6 6 0,000 0,03184813 0,09200017 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03184813 0,09185619 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03184813 0,09171266 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03184813 0,09156959 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03184813 0,09142696 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03184813 0,09128477 ! ruffle organization GO:0031529 6 6 0,000 0,03184813 0,09114302 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03184813 0,09100171 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03184813 0,09086084 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03184813 0,09072041 ! L-amino acid transport GO:0015807 6 6 0,000 0,03184813 0,09058041 ! bone mineralization GO:0030282 6 6 0,000 0,03184813 0,09044084 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03184813 0,0903017 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03184813 0,09016299 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03184813 0,0900247 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03184813 0,08988684 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03184813 0,0897494 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03184813 0,08961237 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03184813 0,08947577 ! regulation of organ growth GO:0046620 6 6 0,000 0,03184813 0,08933958 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03184813 0,08920381 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03184813 0,08906845 ! response to dsRNA GO:0043331 6 6 0,000 0,03184813 0,08893349 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03184813 0,08879895 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03184813 0,08866481 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03184813 0,08853108 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03184813 0,08839775 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03184813 0,08826482 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03184813 0,08813229 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03184813 0,08800016 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03184813 0,08786842 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03184813 0,08773708 ! erythrocyte development GO:0048821 6 6 0,000 0,03184813 0,08760613 ! renal water homeostasis GO:0003091 6 6 0,000 0,03184813 0,08747557 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03184813 0,0873454 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03184813 0,08721561 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03184813 0,08708621 ! ribosome assembly GO:0042255 6 6 0,000 0,03184813 0,08695719 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03184813 0,08682856 ! diencephalon development GO:0021536 6 6 0,000 0,03184813 0,0867003 ! fucose catabolic process GO:0019317 6 6 0,000 0,03184813 0,08657243 GO:0042355|L-fucose catabolic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03184813 0,08644493 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03184813 0,0863178 ! regulation of cell division GO:0051302 6 6 0,000 0,03184813 0,08619105 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03184813 0,08606467 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03184813 0,08593866 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03184813 0,08581302 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03184813 0,08568775 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03184813 0,08556284 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03184813 0,08543829 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03184813 0,08531411 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03184813 0,08519028 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03184813 0,08506682 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03184813 0,08494371 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03184813 0,08482096 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03184813 0,08469857 ! thymus development GO:0048538 6 6 0,000 0,03184813 0,08457652 ! lymph node development GO:0048535 6 6 0,000 0,03184813 0,08445483 ! organic cation transport GO:0015695 6 6 0,000 0,03184813 0,08433349 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03184813 0,08421249 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03184813 0,08409184 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03184813 0,08397154 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03184813 0,08385158 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03184813 0,08373196 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03184813 0,08361269 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03184813 0,08349375 ! alditol metabolic process GO:0019400 6 6 0,000 0,03184813 0,08337515 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03184813 0,08325689 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03184813 0,08313896 ! maternal placenta development GO:0001893 6 6 0,000 0,03184813 0,08302137 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03184813 0,0829041 ! localization within membrane GO:0051668 6 6 0,000 0,03184813 0,08278717 ! tRNA metabolic process GO:0006399 53 53 1,000 0,03265758 0,08477173 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,03265758 0,0846525 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03265758 0,0845336 ! sulfur metabolic process GO:0006790 55 54 1,000 0,03380052 0,08736937 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,03380052 0,08724701 ! in utero embryonic development GO:0001701 55 55 1,000 0,03495906 0,09011124 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,03495906 0,08998539 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,03495906 0,08985989 ! reproductive developmental process GO:0003006 56 56 1,000 0,03613299 0,09274806 ! extracellular structure organization GO:0043062 56 56 1,000 0,03613299 0,09261906 ! regulation of nervous system development GO:0051960 57 56 1,000 0,03613299 0,09249042 ! respiratory burst GO:0045730 7 7 0,000 0,03705931 0,09472996 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03705931 0,09459876 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03705931 0,09446791 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03705931 0,09433743 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03705931 0,09420731 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03705931 0,09407755 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03705931 0,09394815 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03705931 0,0938191 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03705931 0,0936904 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03705931 0,09356206 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03705931 0,09343407 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03705931 0,09330642 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03705931 0,09317913 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03705931 0,09305218 ! axis specification GO:0009798 7 7 0,000 0,03705931 0,09292558 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03705931 0,09279932 ! visual behavior GO:0007632 7 7 0,000 0,03705931 0,09267341 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03705931 0,09254783 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03705931 0,0924226 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03705931 0,09229771 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03705931 0,09217315 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03705931 0,09204892 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03705931 0,09192504 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03705931 0,09180148 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03705931 0,09167826 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03705931 0,09155536 ! digestive system development GO:0055123 7 7 0,000 0,03705931 0,0914328 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03705931 0,09131056 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03705931 0,09118865 ! protein targeting to ER GO:0045047 8 7 0,000 0,03705931 0,09106707 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03705931 0,09094581 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03705931 0,09082487 ! endoderm development GO:0007492 7 7 0,000 0,03705931 0,09070425 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03705931 0,09058395 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03705931 0,09046398 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,03705931 0,09034431 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03705931 0,09022497 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03705931 0,09010594 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03705931 0,08998722 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03705931 0,08986882 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03705931 0,08975072 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03705931 0,08963294 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03705931 0,08951547 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03705931 0,0893983 ! UV protection GO:0009650 7 7 0,000 0,03705931 0,08928144 ! DNA integration GO:0015074 7 7 0,000 0,03705931 0,08916488 ! myofibril assembly GO:0030239 7 7 0,000 0,03705931 0,08904863 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03705931 0,08893268 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03705931 0,08881704 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03705931 0,08870169 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03705931 0,08858664 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03705931 0,08847189 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03705931 0,08835744 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03705931 0,08824328 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03705931 0,08812942 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03705931 0,08801585 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03705931 0,08790258 ! axon cargo transport GO:0008088 7 7 0,000 0,03705931 0,08778959 ! eating behavior GO:0042755 7 7 0,000 0,03705931 0,0876769 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03705931 0,08756449 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03705931 0,08745237 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03705931 0,08734054 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03705931 0,08722899 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03705931 0,08711773 ! cranial nerve development GO:0021545 7 7 0,000 0,03705931 0,08700675 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03705931 0,08689606 ! induction of an organ GO:0001759 7 7 0,000 0,03705931 0,08678564 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03705931 0,08667551 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03705931 0,08656565 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03705931 0,08645608 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03705931 0,08634678 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03705931 0,08623775 ! platelet activation GO:0030168 8 7 0,000 0,03705931 0,08612901 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03705931 0,08602053 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03705931 0,08591233 ! natural killer cell activation GO:0030101 7 7 0,000 0,03705931 0,0858044 ! NADP metabolic process GO:0006739 7 7 0,000 0,03705931 0,08569674 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03705931 0,08558935 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03705931 0,08548223 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03705931 0,08537538 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03705931 0,08526879 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03705931 0,08516247 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03705931 0,08505642 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03705931 0,08495062 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03705931 0,0848451 ! cell-cell recognition GO:0009988 8 7 0,000 0,03705931 0,08473983 ! hormone catabolic process GO:0042447 7 7 0,000 0,03705931 0,08463482 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03705931 0,08453008 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03705931 0,08442559 ! oxygen transport GO:0015671 7 7 0,000 0,03705931 0,08432136 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03705931 0,08421739 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03705931 0,08411367 ! regulation of axon extension GO:0030516 7 7 0,000 0,03705931 0,08401021 ! cell killing GO:0001906 7 7 0,000 0,03705931 0,083907 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03705931 0,08380405 ! adult feeding behavior GO:0008343 7 7 0,000 0,03705931 0,08370135 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03705931 0,0835989 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03705931 0,0834967 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03705931 0,08339475 ! response to cold GO:0009409 7 7 0,000 0,03705931 0,08329305 ! regulation of binding GO:0051098 60 57 1,000 0,03732214 0,08378162 ! regulation of cell development GO:0060284 60 59 1,000 0,03974533 0,08911271 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,040979 0,09176707 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,04222714 0,09444736 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,04222714 0,09433288 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04224319 0,09425447 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04224319 0,0941405 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04224319 0,0940268 ! positive regulation of translation GO:0045727 8 8 0,000 0,04224319 0,09391338 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04224319 0,09380023 ! superoxide anion generation GO:0042554 8 8 0,000 0,04224319 0,09368736 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04224319 0,09357475 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04224319 0,09346242 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04224319 0,09335035 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04224319 0,09323855 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04224319 0,09312702 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04224319 0,09301576 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04224319 0,09290476 ! zinc ion transport GO:0006829 8 8 0,000 0,04224319 0,09279403 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04224319 0,09268356 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04224319 0,09257336 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04224319 0,09246341 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04224319 0,09235373 ! lipid localization GO:0010876 8 8 0,000 0,04224319 0,0922443 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04224319 0,09213514 ! response to cAMP GO:0051591 8 8 0,000 0,04224319 0,09202623 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04224319 0,09191758 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04224319 0,09180919 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04224319 0,09170105 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04224319 0,09159317 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04224319 0,09148554 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04224319 0,09137816 ! sensory perception of taste GO:0050909 8 8 0,000 0,04224319 0,09127103 ! organelle fusion GO:0048284 8 8 0,000 0,04224319 0,09116416 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04224319 0,09105753 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04224319 0,09095116 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04224319 0,09084503 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04224319 0,09073915 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04224319 0,09063352 ! sperm motility GO:0030317 8 8 0,000 0,04224319 0,09052813 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04224319 0,09042299 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04224319 0,09031809 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04224319 0,09021343 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04224319 0,09010902 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04224319 0,09000485 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04224319 0,08990091 ! Golgi organization GO:0007030 8 8 0,000 0,04224319 0,08979722 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04224319 0,08969377 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04224319 0,08959055 ! fructose metabolic process GO:0006000 8 8 0,000 0,04224319 0,08948758 ! mannose metabolic process GO:0006013 9 8 0,000 0,04224319 0,08938484 ! NAD metabolic process GO:0019674 8 8 0,000 0,04224319 0,08928233 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04224319 0,08918006 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04224319 0,08907802 ! response to fungus GO:0009620 8 8 0,000 0,04224319 0,08897622 ! stem cell differentiation GO:0048863 8 8 0,000 0,04224319 0,08887465 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04224319 0,08877331 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04224319 0,0886722 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04224319 0,08857132 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04224319 0,08847067 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04224319 0,08837025 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04224319 0,08827006 ! vasoconstriction GO:0042310 8 8 0,000 0,04224319 0,08817009 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04224319 0,08807035 ! muscle cell development GO:0055001 8 8 0,000 0,04224319 0,08797084 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04224319 0,08787155 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04224319 0,08777248 ! sensory perception of pain GO:0019233 8 8 0,000 0,04224319 0,08767364 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04224319 0,08757502 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04224319 0,08747662 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04224319 0,08737844 ! chromatin silencing GO:0006342 8 8 0,000 0,04224319 0,08728048 ! tissue regeneration GO:0042246 8 8 0,000 0,04224319 0,08718275 ! salivary gland development GO:0007431 8 8 0,000 0,04224319 0,08708523 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04224319 0,08698792 ! T cell homeostasis GO:0043029 8 8 0,000 0,04224319 0,08689084 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04224319 0,08679397 ! water homeostasis GO:0030104 8 8 0,000 0,04224319 0,08669732 ! cofactor transport GO:0051181 8 8 0,000 0,04224319 0,08660088 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04224319 0,08650466 ! acid secretion GO:0046717 8 8 0,000 0,04224319 0,08640865 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04224319 0,08631285 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04224319 0,08621727 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04224319 0,08612189 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04224319 0,08602673 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04224319 0,08593178 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04224319 0,08583704 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04224319 0,0857425 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04224319 0,08564818 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04224319 0,08555406 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04224319 0,08546015 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04224319 0,08536644 ! developmental induction GO:0031128 8 8 0,000 0,04224319 0,08527294 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04224319 0,08517964 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04224319 0,08508655 ! actin filament polymerization GO:0030041 9 8 0,000 0,04224319 0,08499366 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04224319 0,08490097 ! peptide hormone processing GO:0016486 8 8 0,000 0,04224319 0,08480849 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04224319 0,0847162 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04224319 0,08462412 ! axonogenesis GO:0007409 66 62 1,000 0,04348957 0,08702637 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,04348957 0,08693198 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,04348957 0,0868378 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,04605658 0,09186394 ! angiogenesis GO:0001525 65 64 1,000 0,04605658 0,09176463 ! lactation GO:0007595 10 9 0,000 0,04739991 0,09433913 ! embryonic pattern specification GO:0009880 10 9 0,000 0,04739991 0,09423736 ! positive regulation of cell size GO:0045793 9 9 0,000 0,04739991 0,09413581 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,04739991 0,09403448 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,04739991 0,09393337 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,04739991 0,09383247 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,04739991 0,0937318 ! viral genome replication GO:0019079 9 9 0,000 0,04739991 0,09363133 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,04739991 0,09353108 ! copper ion transport GO:0006825 9 9 0,000 0,04739991 0,09343105 ! lipid phosphorylation GO:0046834 9 9 0,000 0,04739991 0,09333123 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,04739991 0,09323163 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,04739991 0,09313223 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,04739991 0,09303305 ! RNA polyadenylation GO:0043631 9 9 0,000 0,04739991 0,09293408 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,04739991 0,09283532 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,04739991 0,09273677 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,04739991 0,09263842 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,04739991 0,09254029 ! phospholipid efflux GO:0033700 9 9 0,000 0,04739991 0,09244236 ! response to alkaloid GO:0043279 10 9 0,000 0,04739991 0,09234464 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,04739991 0,09224713 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,04739991 0,09214982 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,04739991 0,09205272 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,04739991 0,09195582 ! response to ethanol GO:0045471 9 9 0,000 0,04739991 0,09185913 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,04739991 0,09176264 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,04739991 0,09166635 ! methionine metabolic process GO:0006555 9 9 0,000 0,04739991 0,09157027 ! glutamine metabolic process GO:0006541 9 9 0,000 0,04739991 0,09147438 ! cerebral cortex development GO:0021987 9 9 0,000 0,04739991 0,0913787 ! response to osmotic stress GO:0006970 9 9 0,000 0,04739991 0,09128321 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,04739991 0,09118793 ! central nervous system neuron development GO:0021954 10 9 0,000 0,04739991 0,09109284 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,04739991 0,09099795 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,04739991 0,09090326 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,04739991 0,09080877 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,04739991 0,09071447 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,04739991 0,09062037 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,04739991 0,09052646 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,04739991 0,09043275 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,04739991 0,09033923 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,04739991 0,0902459 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,04739991 0,09015277 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,04739991 0,09005983 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,04739991 0,08996708 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,04739991 0,08987452 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,04739991 0,08978215 ! DNA replication initiation GO:0006270 9 9 0,000 0,04739991 0,08968997 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,04739991 0,08959798 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,04739991 0,08950618 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,04739991 0,08941457 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,04739991 0,08932314 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,04739991 0,0892319 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,04739991 0,08914085 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,04739991 0,08904998 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,04739991 0,0889593 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,04739991 0,0888688 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,04739991 0,08877849 ! collagen catabolic process GO:0030574 9 9 0,000 0,04739991 0,08868836 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,04739991 0,08859841 ! purine base metabolic process GO:0006144 9 9 0,000 0,04739991 0,08850865 ! gas transport GO:0015669 9 9 0,000 0,04739991 0,08841906 ! cholesterol efflux GO:0033344 9 9 0,000 0,04739991 0,08832966 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,04739991 0,08824044 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,04739991 0,0881514 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,04739991 0,08806253 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,04739991 0,08797385 ! defense response to virus GO:0051607 9 9 0,000 0,04739991 0,08788535 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,04739991 0,08779702 ! actin filament-based movement GO:0030048 9 9 0,000 0,04739991 0,08770887 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,04739991 0,0876209 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,0486786 0,08989445 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,0486786 0,08980446 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,0500098 0,09216806 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 1,000 0,0500098 0,09207598 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,0500098 0,09198409 ! regulation of cell size GO:0008361 68 68 1,000 0,05135422 0,09436274 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,05252961 0,09642637 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,05252961 0,09633043 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,05252961 0,09623467 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,05252961 0,09613911 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,05252961 0,09604373 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,05252961 0,09594854 ! neuron maturation GO:0042551 10 10 0,000 0,05252961 0,09585354 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,05252961 0,09575873 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,05252961 0,09566411 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,05252961 0,09556967 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,05252961 0,09547542 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,05252961 0,09538136 ! hormone secretion GO:0046879 10 10 0,000 0,05252961 0,09528748 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,05252961 0,09519379 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,05252961 0,09510027 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,05252961 0,09500695 ! cAMP metabolic process GO:0046058 10 10 0,000 0,05252961 0,0949138 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,05252961 0,09482084 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,05252961 0,09472806 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,05252961 0,09463546 ! glial cell development GO:0021782 10 10 0,000 0,05252961 0,09454305 ! phototransduction GO:0007602 11 10 0,000 0,05252961 0,09445081 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,05252961 0,09435875 ! fat cell differentiation GO:0045444 10 10 0,000 0,05252961 0,09426687 ! myoblast differentiation GO:0045445 10 10 0,000 0,05252961 0,09417517 ! centrosome cycle GO:0007098 10 10 0,000 0,05252961 0,09408365 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,05252961 0,09399231 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,05252961 0,09390114 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,05252961 0,09381015 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,05252961 0,09371934 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,05252961 0,0936287 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,05252961 0,09353824 ! protein polyubiquitination GO:0000209 10 10 0,000 0,05252961 0,09344795 ! glutamate metabolic process GO:0006536 11 10 0,000 0,05252961 0,09335784 ! plasma membrane organization GO:0007009 10 10 0,000 0,05252961 0,0932679 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,05252961 0,09317813 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,05252961 0,09308854 ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,05252961 0,09299912 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,05252961 0,09290987 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,05252961 0,09282079 ! exocrine system development GO:0035272 10 10 0,000 0,05252961 0,09273188 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,05252961 0,09264314 ! embryo implantation GO:0007566 11 10 0,000 0,05252961 0,09255457 ! regulation of protein binding GO:0043393 11 10 0,000 0,05252961 0,09246617 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,05252961 0,09237794 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,05252961 0,09228988 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,05252961 0,09220198 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,05252961 0,09211425 ! protein export from nucleus GO:0006611 10 10 0,000 0,05252961 0,09202669 ! negative regulation of immune response GO:0050777 10 10 0,000 0,05252961 0,0919393 ! cytolysis GO:0019835 10 10 0,000 0,05252961 0,09185207 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,05252961 0,091765 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,05252961 0,09167811 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,05252961 0,09159137 ! histone deacetylation GO:0016575 10 10 0,000 0,05252961 0,0915048 ! mRNA splice site selection GO:0006376 11 10 0,000 0,05252961 0,09141839 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,05252961 0,09133215 ! gland morphogenesis GO:0022612 10 10 0,000 0,05252961 0,09124607 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,05252961 0,09116015 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,05252961 0,09107439 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,05252961 0,0909888 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,05252961 0,09090336 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,05252961 0,09081809 ! regulation of epidermis development GO:0045682 10 10 0,000 0,05252961 0,09073297 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,05252961 0,09064801 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,05252961 0,09056322 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,05252961 0,09047858 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,05252961 0,0903941 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,05252961 0,09030978 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,05252961 0,09022561 ! nerve development GO:0021675 10 10 0,000 0,05252961 0,0901416 ! gut development GO:0048565 10 10 0,000 0,05252961 0,09005775 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,05252961 0,08997405 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,05252961 0,08989051 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,05252961 0,08980712 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,05252961 0,08972389 ! protein stabilization GO:0050821 10 10 0,000 0,05252961 0,08964081 ! regionalization GO:0003002 70 69 1,000 0,0527117 0,08986833 ! response to nutrient levels GO:0031667 69 69 1,000 0,0527117 0,08978527 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,0527117 0,08970237 ! cell part morphogenesis GO:0032990 75 70 1,000 0,05408207 0,09194949 ! wound healing GO:0042060 74 70 1,000 0,05408207 0,09186474 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,05408207 0,09178015 GO:0016053|organic acid biosynthetic process, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,05546515 0,09404072 ! regulation of cell activation GO:0050865 71 71 1,000 0,05546515 0,09395429 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,05686077 0,09622994 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,05686077 0,09614165 ! protein secretion GO:0009306 11 11 0,000 0,05763244 0,09735709 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,05763244 0,09726793 ! negative regulation of defense response GO:0031348 11 11 0,000 0,05763244 0,09717894 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,05763244 0,09709011 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,05763244 0,09700145 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,05763244 0,09691294 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,05763244 0,0968246 ! skin development GO:0043588 11 11 0,000 0,05763244 0,09673642 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,05763244 0,09664839 ! signal complex assembly GO:0007172 11 11 0,000 0,05763244 0,09656053 ! microtubule-based transport GO:0010970 11 11 0,000 0,05763244 0,09647283 ! endothelial cell migration GO:0043542 11 11 0,000 0,05763244 0,09638529 ! peroxisomal transport GO:0043574 11 11 0,000 0,05763244 0,0962979 ! protein amino acid methylation GO:0006479 11 11 0,000 0,05763244 0,09621067 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,05763244 0,09612361 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,05763244 0,0960367 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,05763244 0,09594994 ! T cell proliferation GO:0042098 11 11 0,000 0,05763244 0,09586334 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,05763244 0,0957769 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,05763244 0,09569062 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,05763244 0,09560449 ! spinal cord development GO:0021510 11 11 0,000 0,05763244 0,09551851 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,05763244 0,09543269 ! smooth muscle contraction GO:0006939 11 11 0,000 0,05763244 0,09534702 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,05763244 0,09526151 ! digestive system process GO:0022600 11 11 0,000 0,05763244 0,09517615 ! mitotic spindle organization GO:0007052 11 11 0,000 0,05763244 0,09509094 ! fucose metabolic process GO:0006004 11 11 0,000 0,05763244 0,09500589 ! membrane budding GO:0006900 11 11 0,000 0,05763244 0,09492099 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,05763244 0,09483624 ! monoamine transport GO:0015844 11 11 0,000 0,05763244 0,09475164 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,05763244 0,09466719 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,05763244 0,09458289 ! body fluid secretion GO:0007589 11 11 0,000 0,05763244 0,09449874 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,05763244 0,09441474 ! intermediate filament-based process GO:0045103 11 11 0,000 0,05763244 0,09433089 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,05763244 0,09424719 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,05763244 0,09416364 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,05763244 0,09408023 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,05763244 0,09399698 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,05763244 0,09391387 ! oogenesis GO:0048477 11 11 0,000 0,05763244 0,09383091 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,05763244 0,09374809 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,05763244 0,09366542 ! vitamin transport GO:0051180 11 11 0,000 0,05763244 0,09358289 ! muscle maintenance GO:0046716 12 11 0,000 0,05763244 0,09350051 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,05763244 0,09341828 ! hindbrain development GO:0030902 11 11 0,000 0,05763244 0,09333619 ! steroid catabolic process GO:0006706 11 11 0,000 0,05763244 0,09325424 ! endocrine process GO:0050886 11 11 0,000 0,05763244 0,09317244 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,05763244 0,09309078 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,05763244 0,09300927 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,05763244 0,0929279 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,05763244 0,09284667 ! response to oxidative stress GO:0006979 76 75 1,000 0,06112128 0,09838124 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,06256544 0,1006179 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,06256544 0,10053017 ! translational initiation GO:0006413 12 12 0,000 0,06270852 0,1006723 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06270852 0,10058468 ! initiation of viral infection GO:0019059 12 12 0,000 0,06270852 0,10049722 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06270852 0,10040991 ! iron ion transport GO:0006826 13 12 0,000 0,06270852 0,10032274 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06270852 0,10023573 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06270852 0,10014888 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06270852 0,10006217 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06270852 0,09997561 ! collagen metabolic process GO:0032963 12 12 0,000 0,06270852 0,0998892 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06270852 0,09980294 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06270852 0,09971683 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06270852 0,09963086 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06270852 0,09954505 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06270852 0,09945938 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06270852 0,09937386 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06270852 0,09928849 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06270852 0,09920326 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06270852 0,09911818 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06270852 0,09903325 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06270852 0,09894846 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06270852 0,09886382 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06270852 0,09877932 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06270852 0,09869496 ! acute-phase response GO:0006953 12 12 0,000 0,06270852 0,09861075 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06270852 0,09852669 ! vacuolar transport GO:0007034 12 12 0,000 0,06270852 0,09844276 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06270852 0,09835898 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06270852 0,09827534 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06270852 0,09819185 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06270852 0,09810849 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06270852 0,09802528 ! male gonad development GO:0008584 12 12 0,000 0,06270852 0,09794221 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06270852 0,09785927 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06270852 0,09777648 ! renal system process GO:0003014 12 12 0,000 0,06270852 0,09769383 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06270852 0,09761132 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06270852 0,09752895 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06270852 0,09744671 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06270852 0,09736462 ! pallium development GO:0021543 13 12 0,000 0,06270852 0,09728266 ! cell fate determination GO:0001709 12 12 0,000 0,06270852 0,09720084 ! G1 phase GO:0051318 13 12 0,000 0,06270852 0,09711916 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06270852 0,09703762 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06270852 0,09695621 ! detection of light stimulus GO:0009583 13 12 0,000 0,06270852 0,09687494 ! synaptogenesis GO:0007416 12 12 0,000 0,06270852 0,0967938 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06270852 0,09671281 ! hormone transport GO:0009914 12 12 0,000 0,06270852 0,09663194 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06270852 0,09655121 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06270852 0,09647062 ! spermatid differentiation GO:0048515 13 12 0,000 0,06270852 0,09639016 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06270852 0,09630984 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06270852 0,09622964 ! neural tube closure GO:0001843 13 12 0,000 0,06270852 0,09614959 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06270852 0,09606966 ! regulation of protein modification process GO:0031399 79 78 1,000 0,06548879 0,10024572 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,06548879 0,10016253 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,06775799 0,10354725 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,06775799 0,10346146 ! phenol metabolic process GO:0018958 13 13 0,000 0,06775799 0,10337581 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,06775799 0,10329031 ! gluconeogenesis GO:0006094 13 13 0,000 0,06775799 0,10320494 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,06775799 0,10311972 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,06775799 0,10303464 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,06775799 0,1029497 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,06775799 0,10286489 ! regeneration GO:0031099 13 13 0,000 0,06775799 0,10278023 ! keratinization GO:0031424 13 13 0,000 0,06775799 0,10269571 ! post-embryonic development GO:0009791 14 13 0,000 0,06775799 0,10261132 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,06775799 0,10252708 ! patterning of blood vessels GO:0001569 13 13 0,000 0,06775799 0,10244297 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,06775799 0,102359 ! regulation of innate immune response GO:0045088 13 13 0,000 0,06775799 0,10227517 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,06775799 0,10219147 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,06775799 0,10210792 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,06775799 0,1020245 ! autophagy GO:0006914 13 13 0,000 0,06775799 0,10194121 ! receptor metabolic process GO:0043112 14 13 0,000 0,06775799 0,10185806 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,06775799 0,10177505 ! ureteric bud development GO:0001657 13 13 0,000 0,06775799 0,10169217 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,06775799 0,10160942 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,06775799 0,10152681 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,06775799 0,10144434 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,06775799 0,101362 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,06775799 0,10127979 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,06775799 0,10119772 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,06775799 0,10111577 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,06775799 0,10103397 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,06775799 0,10095229 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,06775799 0,10087074 ! vasodilation GO:0042311 14 13 0,000 0,06775799 0,10078933 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,06775799 0,10070805 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,06775799 0,1006269 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,06775799 0,10054588 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,06775799 0,10046499 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,06775799 0,10038423 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,06775799 0,1003036 ! immunoglobulin production GO:0002377 13 13 0,000 0,06775799 0,1002231 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,06775799 0,10014273 ! cell-cell junction organization GO:0045216 13 13 0,000 0,06775799 0,10006249 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,06775799 0,09998237 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,06775799 0,09990239 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,06775799 0,09982253 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,06775799 0,0997428 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,06775799 0,09966319 ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,06775799 0,09958372 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,06775799 0,09950437 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,06775799 0,09942514 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,06775799 0,09934605 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,06775799 0,09926708 ! blastocyst development GO:0001824 13 13 0,000 0,06775799 0,09918823 ! telomere organization GO:0032200 13 13 0,000 0,06775799 0,09910951 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,06775799 0,09903091 ! regulation of amine transport GO:0051952 13 13 0,000 0,06775799 0,09895244 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,06775799 0,09887409 ! neuron projection development GO:0031175 85 80 1,000 0,06845778 0,09981621 ! neuron fate commitment GO:0048663 14 14 0,000 0,072781 0,10603587 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,072781 0,10595211 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,072781 0,10586849 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,072781 0,105785 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,072781 0,10570163 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,072781 0,10561841 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,072781 0,10553531 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,072781 0,10545234 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,072781 0,1053695 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,072781 0,10528679 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,072781 0,10520422 ! vesicle docking GO:0048278 14 14 0,000 0,072781 0,10512177 ! superoxide metabolic process GO:0006801 15 14 0,000 0,072781 0,10503945 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,072781 0,10495726 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,072781 0,1048752 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,072781 0,10479326 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,072781 0,10471146 ! hair cycle GO:0042633 14 14 0,000 0,072781 0,10462978 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,072781 0,10454823 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,072781 0,1044668 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,072781 0,10438551 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,072781 0,10430433 ! lysosome organization GO:0007040 14 14 0,000 0,072781 0,10422329 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,072781 0,10414237 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,072781 0,10406158 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,072781 0,10398091 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,072781 0,10390037 ! primary neural tube formation GO:0014020 15 14 0,000 0,072781 0,10381995 ! peptide cross-linking GO:0018149 14 14 0,000 0,072781 0,10373966 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,072781 0,10365949 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,072781 0,10357944 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,072781 0,10349952 ! formation of primary germ layer GO:0001704 14 14 0,000 0,072781 0,10341972 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,072781 0,10334004 ! collagen fibril organization GO:0030199 14 14 0,000 0,072781 0,10326049 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,072781 0,10318106 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,072781 0,10310175 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,072781 0,10302256 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,072781 0,1029435 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,072781 0,10286455 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,072781 0,10278573 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,072781 0,10270702 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,072781 0,10262844 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,072781 0,10254998 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,07299409 0,10277167 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,07452767 0,10485076 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,07607173 0,10694142 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,07607173 0,10685991 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,07777766 0,10917306 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,07777766 0,10908998 ! positive regulation of ossification GO:0045778 15 15 0,000 0,07777766 0,10900702 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,07777766 0,10892419 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,07777766 0,10884148 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,07777766 0,1087589 ! response to vitamin GO:0033273 15 15 0,000 0,07777766 0,10867644 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,07777766 0,10859411 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,07777766 0,10851191 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,07777766 0,10842982 ! ovarian follicle development GO:0001541 15 15 0,000 0,07777766 0,10834787 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,07777766 0,10826603 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,07777766 0,10818432 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,07777766 0,10810274 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,07777766 0,10802127 ! heme metabolic process GO:0042168 15 15 0,000 0,07777766 0,10793993 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,07777766 0,10785871 ! chromosome condensation GO:0030261 15 15 0,000 0,07777766 0,10777762 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,07777766 0,10769664 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,07777766 0,10761579 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,07777766 0,10753506 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,07777766 0,10745444 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,07777766 0,10737395 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,07777766 0,10729358 ! phospholipid transport GO:0015914 15 15 0,000 0,07777766 0,10721333 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,07777766 0,10713321 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,07777766 0,1070532 ! glutathione metabolic process GO:0006749 16 15 0,000 0,07777766 0,1069733 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,07777766 0,10689353 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,07777766 0,10681388 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,07777766 0,10673435 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,07777766 0,10665493 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,07777766 0,10657563 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,07777766 0,10649646 ! male gamete generation GO:0048232 90 88 1,000 0,08076532 0,11050519 GO:0007283|spermatogenesis, ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,08274812 0,11313412 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,08274812 0,11305025 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,08274812 0,11296651 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,08274812 0,1128829 ! learning GO:0007612 16 16 0,000 0,08274812 0,1127994 ! circadian rhythm GO:0007623 16 16 0,000 0,08274812 0,11271603 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,08274812 0,11263279 ! vacuole organization GO:0007033 16 16 0,000 0,08274812 0,11254966 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,08274812 0,11246666 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,08274812 0,11238378 ! vesicle targeting GO:0006903 17 16 0,000 0,08274812 0,11230102 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,08274812 0,11221839 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,08274812 0,11213588 ! iron ion homeostasis GO:0055072 16 16 0,000 0,08274812 0,11205348 ! positive regulation of cell development GO:0010720 16 16 0,000 0,08274812 0,11197121 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,08274812 0,11188906 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,08274812 0,11180703 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,08274812 0,11172512 ! cell fate specification GO:0001708 16 16 0,000 0,08274812 0,11164333 ! pentose metabolic process GO:0019321 16 16 0,000 0,08274812 0,11156166 ! fatty acid transport GO:0015908 16 16 0,000 0,08274812 0,11148011 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,08274812 0,11139868 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,08274812 0,11131737 ! cofactor catabolic process GO:0051187 16 16 0,000 0,08274812 0,11123617 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,08274812 0,1111551 ! polyol metabolic process GO:0019751 16 16 0,000 0,08274812 0,11107414 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,08274812 0,1109933 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,08274812 0,11091258 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,08274812 0,11083197 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,08274812 0,11075148 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,08274812 0,11067111 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,08274812 0,11059086 ! regulation of coagulation GO:0050818 17 16 0,000 0,08274812 0,11051072 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,08394409 0,11202676 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,08554795 0,11408456 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,08716127 0,116152 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,08716127 0,11606807 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,08769252 0,1166912 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,08769252 0,11660701 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,08769252 0,11652293 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,08769252 0,11643898 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,08769252 0,11635515 ! leukocyte adhesion GO:0007159 17 17 0,000 0,08769252 0,11627145 ! sensory perception of smell GO:0007608 17 17 0,000 0,08769252 0,11618786 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,08769252 0,11610439 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,08769252 0,11602104 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,08769252 0,11593781 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,08769252 0,1158547 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,08769252 0,11577171 ! neural crest cell development GO:0014032 19 17 0,000 0,08769252 0,11568884 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,08769252 0,11560609 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,08769252 0,11552345 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,08769252 0,11544094 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,08769252 0,11535854 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,08769252 0,11527625 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,08769252 0,11519409 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,08769252 0,11511204 ! adult locomotory behavior GO:0008344 17 17 0,000 0,08769252 0,11503011 ! embryonic organ development GO:0048568 17 17 0,000 0,08769252 0,1149483 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,08769252 0,1148666 ! liver development GO:0001889 17 17 0,000 0,08769252 0,11478502 ! gene silencing GO:0016458 17 17 0,000 0,08769252 0,11470356 ! blood vessel development GO:0001568 95 94 1,000 0,09041572 0,11818168 ! pattern specification process GO:0007389 96 94 1,000 0,09041572 0,11809793 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09261098 0,12087962 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,09261098 0,12079407 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09261098 0,12070865 ! membrane docking GO:0022406 18 18 0,000 0,09261098 0,12062334 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09261098 0,12053815 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,09261098 0,12045309 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,09261098 0,12036814 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09261098 0,12028332 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09261098 0,12019861 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,09261098 0,12011402 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,09261098 0,12002955 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,09261098 0,11994521 ! ceramide metabolic process GO:0006672 18 18 0,000 0,09261098 0,11986097 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,09261098 0,11977686 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,09261098 0,11969287 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,09261098 0,11960899 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09261098 0,11952523 ! BMP signaling pathway GO:0030509 18 18 0,000 0,09261098 0,11944159 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,09261098 0,11935806 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,09261098 0,11927465 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09261098 0,11919136 ! vasculature development GO:0001944 97 96 1,000 0,09370633 0,12051694 ! endocytosis GO:0006897 99 98 1,000 0,09703201 0,12470711 GO:0010324|membrane invagination, ! blood circulation GO:0008015 99 98 1,000 0,09703201 0,1246202 GO:0003013|circulatory system process, ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,09750363 0,12513871 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,09750363 0,12505163 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,09750363 0,12496467 ! feeding behavior GO:0007631 19 19 0,000 0,09750363 0,12487782 ! peroxisome organization GO:0007031 19 19 0,000 0,09750363 0,1247911 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,09750363 0,1247045 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,09750363 0,12461802 ! metanephros development GO:0001656 19 19 0,000 0,09750363 0,12453166 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,09750363 0,12444542 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,09750363 0,1243593 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,09750363 0,1242733 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,09750363 0,12418741 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,09750363 0,12410165 ! regulation of protein stability GO:0031647 19 19 0,000 0,09750363 0,124016 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,09750363 0,12393048 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,09750363 0,12384506 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,09750363 0,12375977 ! eye morphogenesis GO:0048592 19 19 0,000 0,09750363 0,1236746 ! placenta development GO:0001890 19 19 0,000 0,09750363 0,12358954 ! vesicle localization GO:0051648 20 19 0,000 0,09750363 0,1235046 ! regulation of muscle development GO:0048634 21 20 0,000 0,10237061 0,12958038 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,10237061 0,12949145 ! negative regulation of binding GO:0051100 21 20 0,000 0,10237061 0,12940263 ! organic ether metabolic process GO:0018904 20 20 0,000 0,10237061 0,12931394 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,10237061 0,12922537 ! neural tube development GO:0021915 21 20 0,000 0,10237061 0,12913692 ! nucleus organization GO:0006997 20 20 0,000 0,10237061 0,12904859 ! phagocytosis GO:0006909 21 20 0,000 0,10237061 0,12896038 ! protein targeting to membrane GO:0006612 22 20 0,000 0,10237061 0,12887229 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,10237061 0,12878433 ! chromatin remodeling GO:0006338 20 20 0,000 0,10237061 0,12869648 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,10237061 0,12860875 ! lipid oxidation GO:0034440 20 20 0,000 0,10237061 0,12852114 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,10237061 0,12843365 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,10237061 0,12834628 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,10237061 0,12825903 ! RNA modification GO:0009451 20 20 0,000 0,10237061 0,1281719 ! single fertilization GO:0007338 21 20 0,000 0,10237061 0,12808489 ! regulation of B cell activation GO:0050864 20 20 0,000 0,10237061 0,12799799 ! mRNA catabolic process GO:0006402 21 21 0,000 0,10721205 0,13396055 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,10721205 0,13386979 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,10721205 0,13377916 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,10721205 0,13368864 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,10721205 0,13359825 ! Notch signaling pathway GO:0007219 22 21 0,000 0,10721205 0,13350798 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,10721205 0,13341784 ! ear morphogenesis GO:0042471 21 21 0,000 0,10721205 0,13332781 ! organic anion transport GO:0015711 21 21 0,000 0,10721205 0,13323791 ! cholesterol transport GO:0030301 21 21 0,000 0,10721205 0,13314812 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,10721205 0,13305846 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,10721205 0,13296892 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,10721205 0,1328795 ! regulation of proteolysis GO:0030162 21 21 0,000 0,10721205 0,1327902 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,10721205 0,13270102 ! RNA export from nucleus GO:0006405 22 22 0,000 0,11202808 0,13856897 ! regulation of ion transport GO:0043269 22 22 0,000 0,11202808 0,13847603 ! odontogenesis GO:0042476 22 22 0,000 0,11202808 0,13838322 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,11202808 0,13829053 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,11202808 0,13819796 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,11202808 0,13810552 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,11202808 0,13801321 ! ovulation cycle process GO:0022602 22 22 0,000 0,11202808 0,13792101 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,11202808 0,13782894 ! cell chemotaxis GO:0060326 23 22 0,000 0,11202808 0,137737 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,11202808 0,13764517 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,11202808 0,13755347 ! male sex differentiation GO:0046661 22 22 0,000 0,11202808 0,13746189 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,11202808 0,13737043 ! biopolymer methylation GO:0043414 22 22 0,000 0,11202808 0,13727909 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,11202808 0,13718788 ! detection of external stimulus GO:0009581 23 22 0,000 0,11202808 0,13709679 ! neuron migration GO:0001764 22 22 0,000 0,11202808 0,13700581 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,11202808 0,13691496 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,11202808 0,13682423 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,11202808 0,13673361 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,11202808 0,13664312 ! aerobic respiration GO:0009060 22 22 0,000 0,11202808 0,13655275 ! cytokine production GO:0001816 22 22 0,000 0,11202808 0,1364625 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,11202808 0,13637236 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,11681883 0,1421103 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,11681883 0,14201656 ! viral infectious cycle GO:0019058 23 23 0,000 0,11681883 0,14192295 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,11681883 0,14182945 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,11681883 0,14173608 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,11681883 0,14164284 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,11681883 0,14154971 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,11681883 0,14145671 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,11681883 0,14136383 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,11681883 0,14127107 ! female gonad development GO:0008585 23 23 0,000 0,11681883 0,14117843 ! lipid homeostasis GO:0055088 23 23 0,000 0,11681883 0,14108592 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,11681883 0,14099352 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,11681883 0,14090125 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,11681883 0,1408091 ! gliogenesis GO:0042063 24 24 0,000 0,12158443 0,14645759 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,12158443 0,14636192 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,12158443 0,14626639 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,12158443 0,14617098 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,12158443 0,14607569 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,12158443 0,14598053 ! ovulation cycle GO:0042698 24 24 0,000 0,12158443 0,14588549 ! fertilization GO:0009566 25 24 0,000 0,12158443 0,14579057 ! maintenance of protein location GO:0045185 25 24 0,000 0,12158443 0,14569578 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,12158443 0,14560111 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,12158443 0,14550656 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,12632501 0,15108175 ! negative regulation of secretion GO:0051048 26 25 0,000 0,12632501 0,15098378 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,12632501 0,15088593 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,12632501 0,1507882 ! cellular component disassembly GO:0022411 26 25 0,000 0,12632501 0,1506906 ! endosome transport GO:0016197 25 25 0,000 0,12632501 0,15059313 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,12632501 0,15049579 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,12632501 0,15039857 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,12632501 0,15030147 ! excretion GO:0007588 25 25 0,000 0,12632501 0,15020451 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,12632501 0,15010766 ! gastrulation GO:0007369 25 25 0,000 0,12632501 0,15001094 ! regulation of endocytosis GO:0030100 25 25 0,000 0,12632501 0,14991435 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,12632501 0,14981788 ! positive regulation of defense response GO:0031349 26 26 0,000 0,13104068 0,1553106 ! glycolysis GO:0006096 26 26 0,000 0,13104068 0,15521078 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,13104068 0,1551111 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,13104068 0,15501154 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,13104068 0,15491211 ! cellular defense response GO:0006968 26 26 0,000 0,13104068 0,15481281 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,13104068 0,15471363 ! regulation of protein secretion GO:0050708 26 26 0,000 0,13104068 0,15461458 ! germ cell development GO:0007281 27 26 0,000 0,13104068 0,15451566 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,13104068 0,15441687 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,13104068 0,1543182 ! maintenance of location in cell GO:0051651 27 26 0,000 0,13104068 0,15421965 ! chloride transport GO:0006821 27 27 0,000 0,13573159 0,15963837 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,13573159 0,15953656 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,13573159 0,15943488 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,13573159 0,15933333 ! peptide metabolic process GO:0006518 29 27 0,000 0,13573159 0,15923191 ! inner ear development GO:0048839 27 27 0,000 0,13573159 0,15913061 ! defense response to bacterium GO:0042742 27 27 0,000 0,13573159 0,15902945 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,13573159 0,15892842 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,13573159 0,15882751 ! cell growth GO:0016049 27 27 0,000 0,13573159 0,15872673 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,14039786 0,16407943 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,14039786 0,16397545 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,14039786 0,1638716 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,14039786 0,16376788 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,14039786 0,1636643 ! developmental growth GO:0048589 28 28 0,000 0,14039786 0,16356085 ! cartilage development GO:0051216 29 28 0,000 0,14039786 0,16345752 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,14503961 0,16875505 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,14503961 0,16864858 ! leukocyte migration GO:0050900 30 29 0,000 0,14503961 0,16854225 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,14503961 0,16843605 ! antigen processing and presentation GO:0019882 29 29 0,000 0,14503961 0,16832998 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,14503961 0,16822404 ! tRNA processing GO:0008033 29 29 0,000 0,14503961 0,16811824 ! adult behavior GO:0030534 30 29 0,000 0,14503961 0,16801257 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,14503961 0,16790704 ! transition metal ion transport GO:0000041 31 30 0,000 0,14965697 0,17314363 ! RNA catabolic process GO:0006401 30 30 0,000 0,14965697 0,17303501 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,14965697 0,17292652 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,14965697 0,17281817 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,14965697 0,17270996 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,14965697 0,17260188 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,14965697 0,17249393 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,14965697 0,17238612 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,14965697 0,17227845 ! regulation of ossification GO:0030278 30 30 0,000 0,14965697 0,17217091 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,14965697 0,17206351 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,14965697 0,17195623 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,14965697 0,1718491 ! vesicle organization GO:0016050 30 30 0,000 0,14965697 0,17174209 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,14965697 0,17163522 ! membrane fusion GO:0006944 31 31 0,000 0,15425007 0,17679283 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,15425007 0,17668295 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,15425007 0,17657321 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,15425007 0,17646361 ! ion transmembrane transport GO:0034220 31 31 0,000 0,15425007 0,17635414 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,15425007 0,17624481 ! digestion GO:0007586 31 31 0,000 0,15425007 0,17613561 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,15425007 0,17602655 ! regulation of heart contraction GO:0008016 31 31 0,000 0,15425007 0,17591762 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,15425007 0,17580883 ! camera-type eye development GO:0043010 31 31 0,000 0,15425007 0,17570017 ! extracellular matrix organization GO:0030198 31 31 0,000 0,15425007 0,17559164 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,15425007 0,17548325 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,15425007 0,175375 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,15425007 0,17526687 ! cell redox homeostasis GO:0045454 32 32 0,000 0,15881902 0,18034716 ! glucose catabolic process GO:0006007 32 32 0,000 0,15881902 0,18023611 ! lipid modification GO:0030258 32 32 0,000 0,15881902 0,1801252 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,15881902 0,18001442 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,15881902 0,17990378 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,15881902 0,17979327 ! cell maturation GO:0048469 32 32 0,000 0,15881902 0,1796829 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,15881902 0,17957267 ! nuclear export GO:0051168 32 32 0,000 0,15881902 0,17946257 ! kidney development GO:0001822 32 32 0,000 0,15881902 0,1793526 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,15881902 0,17924277 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,15881902 0,17913308 ! maintenance of location GO:0051235 33 32 0,000 0,15881902 0,17902352 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,16336395 0,18403408 ! amino acid transport GO:0006865 33 33 0,000 0,16336395 0,18392166 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,16336395 0,18380938 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,16336395 0,18369723 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,16336395 0,18358522 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,16336395 0,18347334 ! regulation of actin filament length GO:0030832 34 34 0,000 0,16788499 0,18843607 ! response to metal ion GO:0010038 34 34 0,000 0,16788499 0,18832138 ! ear development GO:0043583 34 34 0,000 0,16788499 0,18820683 ! muscle cell differentiation GO:0042692 35 34 0,000 0,16788499 0,18809242 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,16788499 0,18797815 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,16788499 0,18786401 ! secondary metabolic process GO:0019748 34 34 0,000 0,16788499 0,18775002 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,16788499 0,18763616 ! detection of stimulus GO:0051606 36 34 0,000 0,16788499 0,18752244 ! acute inflammatory response GO:0002526 35 35 0,000 0,17238225 0,19242912 ! regulation of cellular component size GO:0032535 35 35 0,000 0,17238225 0,19231264 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,17238225 0,1921963 ! mesoderm development GO:0007498 35 35 0,000 0,17238225 0,1920801 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,17238225 0,19196404 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,17238225 0,19184812 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,17238225 0,19173234 ! regulation of immune effector process GO:0002697 35 35 0,000 0,17238225 0,1916167 ! hydrogen transport GO:0006818 36 36 0,000 0,17685586 0,19647097 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,17685586 0,19635262 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,17685586 0,1962344 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,17685586 0,19611633 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,17685586 0,1959984 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,17685586 0,19588062 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,17685586 0,19576297 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,17685586 0,19564546 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,17685586 0,1955281 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,17685586 0,19541088 ! gonad development GO:0008406 36 36 0,000 0,17685586 0,1952938 ! regulation of lipase activity GO:0060191 36 36 0,000 0,17685586 0,19517685 ! activation of immune response GO:0002253 36 36 0,000 0,17685586 0,19506005 ! coagulation GO:0050817 39 36 0,000 0,17685586 0,19494339 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,18130593 0,19972913 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,18130593 0,19960982 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,18130593 0,19949065 ! eye development GO:0001654 37 37 0,000 0,18130593 0,19937162 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,18130593 0,19925274 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,18130593 0,19913399 ! positive regulation of secretion GO:0051047 39 38 0,000 0,1857326 0,20387444 ! neurotransmitter transport GO:0006836 40 38 0,000 0,1857326 0,20375309 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,1857326 0,20363188 ! exocytosis GO:0006887 40 38 0,000 0,1857326 0,20351081 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,1857326 0,20338989 ! urogenital system development GO:0001655 38 38 0,000 0,1857326 0,20326911 ! hexose catabolic process GO:0019320 38 38 0,000 0,1857326 0,20314848 ! RNA elongation GO:0006354 38 38 0,000 0,1857326 0,20302799 ! regulation of neurological system process GO:0031644 38 38 0,000 0,1857326 0,20290764 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,19013598 0,20759515 ! hemostasis GO:0007599 42 39 0,000 0,19013598 0,20747224 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,19013598 0,20734947 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,19013598 0,20722685 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,19013598 0,20710438 ! developmental maturation GO:0021700 39 39 0,000 0,19013598 0,20698205 ! limb development GO:0060173 39 39 0,000 0,19013598 0,20685986 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,19451618 0,21150048 ! DNA catabolic process GO:0006308 41 40 0,000 0,19451618 0,21137578 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,19451618 0,21125122 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,19887333 0,21585603 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,19887333 0,21572898 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,19887333 0,21560209 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,19887333 0,21547534 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,19887333 0,21534873 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,19887333 0,21522228 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,19887333 0,21509598 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,20320754 0,21965484 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,20320754 0,21952608 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,20320754 0,21939748 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,20320754 0,21926903 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,20320754 0,21914073 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,20320754 0,21901257 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,20320754 0,21888457 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,20320754 0,21875672 ! reproductive structure development GO:0048608 43 43 0,000 0,20751894 0,2232676 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,20751894 0,22313734 ! alcohol catabolic process GO:0046164 43 43 0,000 0,20751894 0,22300723 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,20751894 0,22287727 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,20751894 0,22274747 ! humoral immune response GO:0006959 44 44 0,000 0,21180763 0,22721855 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,21180763 0,22708637 ! vitamin metabolic process GO:0006766 44 44 0,000 0,21180763 0,22695434 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,21180763 0,22682247 ! amine biosynthetic process GO:0009309 46 45 0,000 0,21607374 0,23125662 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,21607374 0,2311224 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,21607374 0,23098834 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,21607374 0,23085444 ! protein processing GO:0016485 45 45 0,000 0,21607374 0,23072069 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,22031738 0,23511577 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,22031738 0,2349797 ! tube morphogenesis GO:0035239 47 46 0,000 0,22031738 0,2348438 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,22031738 0,23470805 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,22031738 0,23457246 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,22031738 0,23443703 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,22453866 0,23879097 ! regulation of blood pressure GO:0008217 48 47 0,000 0,22453866 0,23865326 ! sex differentiation GO:0007548 47 47 0,000 0,22453866 0,23851571 ! amine transport GO:0015837 47 47 0,000 0,22453866 0,23837832 ! rhythmic process GO:0048511 47 47 0,000 0,22453866 0,23824108 ! calcium ion transport GO:0006816 48 48 0,000 0,22873771 0,24255673 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,22873771 0,24241725 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,22873771 0,24227793 ! DNA recombination GO:0006310 48 48 0,000 0,22873771 0,24213877 ! ossification GO:0001503 50 49 0,000 0,23291463 0,24641886 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,23291463 0,24627748 ! divalent metal ion transport GO:0070838 49 49 0,000 0,23291463 0,24613627 ! response to nutrient GO:0007584 49 49 0,000 0,23291463 0,24599522 ! response to bacterium GO:0009617 50 49 0,000 0,23291463 0,24585433 ! regulation of ligase activity GO:0051340 50 49 0,000 0,23291463 0,2457136 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,23291463 0,24557303 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,23291463 0,24543262 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,23706953 0,24966808 ! chromatin assembly GO:0031497 50 50 0,000 0,23706953 0,2495255 GO:0006334|nucleosome assembly, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,23706953 0,24938307 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,23706953 0,24924081 ! transcription initiation GO:0006352 50 50 0,000 0,23706953 0,24909871 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,24120254 0,25329702 ! positive regulation of immune response GO:0050778 51 51 0,000 0,24120254 0,25315278 ! rRNA metabolic process GO:0016072 51 51 0,000 0,24120254 0,25300869 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,24120254 0,25286478 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,24120254 0,25272102 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,24120254 0,25257743 ! protein maturation GO:0051604 51 51 0,000 0,24120254 0,252434 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,24531375 0,25659095 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,24531375 0,25644541 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,24531375 0,25630003 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,24531375 0,25615482 ! sodium ion transport GO:0006814 53 53 0,000 0,2494033 0,26027762 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,2494033 0,26013032 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,2494033 0,25998319 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,25347127 0,26407437 ! hormone metabolic process GO:0042445 55 54 0,000 0,25347127 0,26392517 ! nucleosome organization GO:0034728 55 55 0,000 0,2575178 0,26798718 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,2575178 0,26783595 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,26154297 0,27186898 ! ATP metabolic process GO:0046034 57 57 0,000 0,26554692 0,2758754 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,26554692 0,27571998 ! innate immune response GO:0045087 58 58 0,000 0,26952973 0,2796978 ! dephosphorylation GO:0016311 60 59 0,000 0,27349153 0,28364935 ! carboxylic acid transport GO:0046942 59 59 0,000 0,27349153 0,28348982 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,27349153 0,28333047 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,27349153 0,28317129 ! immune effector process GO:0002252 59 59 0,000 0,27349153 0,2830123 ! potassium ion transport GO:0006813 60 60 0,000 0,27743243 0,28692927 ! protein polymerization GO:0051258 65 60 0,000 0,27743243 0,28676835 ! cellular respiration GO:0045333 62 61 0,000 0,28135251 0,29065733 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,28135251 0,2904945 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,28135251 0,29033185 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,28525191 0,29419097 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,28525191 0,29402643 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,28525191 0,29386208 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,28525191 0,29369791 ! regulation of secretion GO:0051046 65 63 0,000 0,28913071 0,29752535 ! glucose metabolic process GO:0006006 63 63 0,000 0,28913071 0,29735932 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,28913071 0,29719347 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,28913071 0,29702781 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,29298903 0,30082383 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,29298903 0,30065634 ! anion transport GO:0006820 65 65 0,000 0,29682697 0,30442521 ! regulation of hormone levels GO:0010817 66 65 0,000 0,29682697 0,3042559 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,30064464 0,30799781 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,30064464 0,3078267 ! DNA packaging GO:0006323 66 66 0,000 0,30064464 0,30765578 ! muscle contraction GO:0006936 67 67 0,000 0,30444213 0,31136895 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,30821957 0,31505749 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,30821957 0,31488285 ! sensory perception of sound GO:0007605 71 69 0,000 0,31197703 0,31854497 GO:0050954|sensory perception of mechanical stimulus, ! growth GO:0040007 70 70 0,000 0,31571464 0,32218277 ! translational elongation GO:0006414 71 71 0,000 0,31943249 0,32579639 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,31943249 0,3256162 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,31943249 0,3254362 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,31943249 0,3252564 ! secretion by cell GO:0032940 75 72 0,000 0,32313069 0,32884034 ! muscle system process GO:0003012 72 72 0,000 0,32313069 0,32865886 ! sensory organ development GO:0007423 72 72 0,000 0,32313069 0,32847758 ! regulation of cytokine production GO:0001817 72 72 0,000 0,32313069 0,3282965 ! electron transport chain GO:0022900 75 74 0,000 0,33046851 0,33556664 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,33046851 0,33538186 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,33410833 0,33888919 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,33410833 0,33870278 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,34133032 0,34583385 ! microtubule-based movement GO:0007018 82 78 0,000 0,34491268 0,34927146 ! metal ion homeostasis GO:0055065 78 78 0,000 0,34491268 0,34907966 ! regulation of immune response GO:0050776 78 78 0,000 0,34491268 0,34888807 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,35202061 0,3558826 ! lipid catabolic process GO:0016042 82 81 0,000 0,35554638 0,35924999 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,36254201 0,36611777 ! ncRNA processing GO:0034470 83 83 0,000 0,36254201 0,36591727 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,36946373 0,37269932 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,37289712 0,375957 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,37289712 0,37575144 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,3797094 0,38240679 ! chemotaxis GO:0006935 90 89 0,000 0,38308849 0,38559917 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,38308849 0,38538869 ! brain development GO:0007420 91 90 0,000 0,38644966 0,38855795 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,38979301 0,39170585 ! DNA replication GO:0006260 91 91 0,000 0,38979301 0,39149238 ! visual perception GO:0007601 93 92 0,000 0,39311864 0,39461745 GO:0050953|sensory perception of light stimulus, ! tissue morphogenesis GO:0048729 94 93 0,000 0,39642662 0,39772143 ! regulation of response to stress GO:0080134 97 94 0,000 0,39971706 0,40080443 ! epidermis development GO:0008544 94 94 0,000 0,39971706 0,40058648 ! cofactor metabolic process GO:0051186 95 94 0,000 0,39971706 0,40036877 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,41270516 0,41315351 ! regulation of system process GO:0044057 98 98 0,000 0,41270516 0,41292921 ! ectoderm development GO:0007398 99 99 0,000 0,41590922 0,41590922