pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6851-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 10 5 3,000 5,656E-09 1,301E-05 ! establishment of nucleus localization GO:0040023 13 7 3,000 3,924E-08 4,512E-05 ! nucleus localization GO:0051647 15 9 3,000 1,4E-07 1,073E-04 ! insulin receptor signaling pathway GO:0008286 40 24 4,000 2,503E-07 1,439E-04 ! cellular response to insulin stimulus GO:0032869 52 34 4,000 1,564E-06 7,194E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 1,969E-06 7,549E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of protein export from nucleus GO:0046825 6 6 2,000 3,922E-06 1,289E-03 ! ER overload response GO:0006983 7 6 2,000 3,922E-06 1,128E-03 ! macrophage differentiation GO:0030225 10 6 2,000 3,922E-06 1,002E-03 ! cellular response to hormone stimulus GO:0032870 109 74 5,000 4,837E-06 1,113E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 5,188E-06 1,085E-03 ! response to insulin stimulus GO:0032868 63 43 4,000 5,188E-06 9,943E-04 ! myeloid leukocyte differentiation GO:0002573 33 21 3,000 6,297E-06 1,114E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 3,000 6,297E-06 1,034E-03 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 6,834E-06 1,048E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 3,000 9,232E-06 1,327E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 3,000 9,232E-06 1,249E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 1,089E-05 1,391E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 1,089E-05 1,318E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 1,089E-05 1,252E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 1,089E-05 1,192E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,089E-05 1,138E-03 ! peptidyl-tyrosine modification GO:0018212 37 25 3,000 1,307E-05 1,307E-03 ! establishment of organelle localization GO:0051656 85 52 4,000 1,343E-05 1,287E-03 ! leukocyte differentiation GO:0002521 143 90 5,000 1,507E-05 1,386E-03 ! peptidyl-amino acid modification GO:0018193 147 93 5,000 1,819E-05 1,609E-03 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 2,114E-05 1,801E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 2,313E-05 1,9E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 2,313E-05 1,834E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 2,000 2,313E-05 1,773E-03 ! filopodium assembly GO:0046847 19 11 2,000 3,167E-05 2,35E-03 ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 3,167E-05 2,276E-03 GO:0042130|negative regulation of T cell proliferation, ! organelle localization GO:0051640 96 62 4,000 3,192E-05 2,224E-03 ! microspike assembly GO:0030035 23 12 2,000 4,204E-05 2,844E-03 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 5,17E-05 3,398E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 2,000 6,897E-05 4,406E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 8,584E-05 5,336E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 8,823E-05 5,34E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 1,071E-04 6,315E-03 ! regulation of gene-specific transcription GO:0032583 69 43 3,000 1,175E-04 6,758E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 1,272E-04 7,135E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 1,287E-04 7,048E-03 ! microtubule cytoskeleton organization GO:0000226 120 84 4,000 1,374E-04 7,351E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 1,406E-04 7,351E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 4,000 1,454E-04 7,429E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 1,52E-04 7,599E-03 ! negative regulation of T cell activation GO:0050868 25 18 2,000 1,52E-04 7,437E-03 ! cell cycle arrest GO:0007050 150 86 4,000 1,536E-04 7,36E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 1,536E-04 7,21E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 1,668E-04 7,675E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! interphase GO:0051325 159 88 4,000 1,712E-04 7,721E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 1,797E-04 7,948E-03 ! regulation of DNA replication GO:0006275 75 48 3,000 1,812E-04 7,863E-03 ! regulation of intracellular transport GO:0032386 78 49 3,000 1,964E-04 8,365E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 2,296E-04 9,6E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 2,296E-04 9,429E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 2,445E-04 9,868E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 2,82E-04 0,01118088 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 2,000 2,82E-04 0,01099137 ! protein tetramerization GO:0051262 39 22 2,000 2,82E-04 0,01080818 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 3,229E-04 0,01217343 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 3,229E-04 0,01197708 ! positive regulation of cell motion GO:0051272 99 56 3,000 3,299E-04 0,01204357 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,398E-04 0,01221242 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,398E-04 0,01202453 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 3,398E-04 0,01184234 ! positive regulation of glycolysis GO:0045821 11 5 1,000 3,398E-04 0,01166559 ! epithelial cell proliferation GO:0050673 6 5 1,000 3,398E-04 0,01149404 ! valine metabolic process GO:0006573 8 5 1,000 3,398E-04 0,01132746 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 3,398E-04 0,01116564 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 8 5 1,000 3,398E-04 0,01100838 ! regulation of respiratory burst GO:0060263 8 5 1,000 3,398E-04 0,01085548 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 3,398E-04 0,01070678 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 3,532E-04 0,01097756 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 3,674E-04 0,01126718 ! negative regulation of cell development GO:0010721 56 24 2,000 3,674E-04 0,01111893 GO:0050768|negative regulation of neurogenesis, ! negative regulation of kinase activity GO:0033673 100 58 3,000 3,776E-04 0,01128039 ! myeloid cell differentiation GO:0030099 85 59 3,000 4,033E-04 0,01189195 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 4,157E-04 0,01210344 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 4,157E-04 0,01195215 ! negative regulation of transferase activity GO:0051348 105 61 3,000 4,583E-04 0,01301273 ! negative regulation of cell growth GO:0030308 106 62 3,000 4,877E-04 0,01367879 ! regulation of helicase activity GO:0051095 11 6 1,000 5,078E-04 0,01407087 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 5,078E-04 0,01390336 ! mRNA stabilization GO:0048255 15 6 1,000 5,078E-04 0,01373979 GO:0043489|RNA stabilization, ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 5,078E-04 0,01358002 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 5,078E-04 0,01342393 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 5,078E-04 0,01327139 ! male sex determination GO:0030238 9 6 1,000 5,078E-04 0,01312227 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 5,078E-04 0,01297647 ! negative regulation of B cell activation GO:0050869 9 6 1,000 5,078E-04 0,01283387 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 5,078E-04 0,01269437 ! regulation of transcription factor activity GO:0051090 97 63 3,000 5,184E-04 0,0128207 GO:0090046|regulation of transcription regulator activity, ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 5,242E-04 0,01282601 ! negative regulation of transcription regulator activity GO:0090048 47 27 2,000 5,242E-04 0,012691 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of cell size GO:0045792 108 64 3,000 5,505E-04 0,01318855 ! regulation of caspase activity GO:0043281 97 65 3,000 5,839E-04 0,01384603 ! protein oligomerization GO:0051259 100 65 3,000 5,839E-04 0,01370474 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 5,846E-04 0,01358144 ! positive regulation of catabolic process GO:0009896 40 28 2,000 5,846E-04 0,01344563 ! regulation of B cell activation GO:0050864 42 28 2,000 5,846E-04 0,0133125 ! regulation of endopeptidase activity GO:0052548 99 67 3,000 6,552E-04 0,0147732 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 7,082E-04 0,01581309 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 7,082E-04 0,01566104 ! microtubule bundle formation GO:0001578 8 7 1,000 7,082E-04 0,01551188 ! T-helper 1 type immune response GO:0042088 11 7 1,000 7,082E-04 0,01536555 ! protein heterooligomerization GO:0051291 10 7 1,000 7,082E-04 0,01522194 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 7,082E-04 0,015081 ! B cell lineage commitment GO:0002326 17 7 1,000 7,082E-04 0,01494264 ! T cell lineage commitment GO:0002360 12 7 1,000 7,082E-04 0,0148068 ! response to tumor cell GO:0002347 12 7 1,000 7,082E-04 0,0146734 ! neuroblast proliferation GO:0007405 13 7 1,000 7,082E-04 0,01454239 ! spindle organization GO:0007051 37 30 2,000 7,183E-04 0,01462087 ! negative regulation of cell activation GO:0050866 44 30 2,000 7,183E-04 0,01449262 ! regulation of peptidase activity GO:0052547 106 72 3,000 8,598E-04 0,01719637 ! meiosis I GO:0007127 52 32 2,000 8,701E-04 0,01725201 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 9,406E-04 0,01848989 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 9,406E-04 0,01833319 ! induction of positive chemotaxis GO:0050930 14 8 1,000 9,406E-04 0,01817913 ! succinate metabolic process GO:0006105 14 8 1,000 9,406E-04 0,01802764 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 9,406E-04 0,01787865 ! regulation of vascular permeability GO:0043114 12 8 1,000 9,406E-04 0,01773211 ! regulation of gliogenesis GO:0014013 20 8 1,000 9,406E-04 0,01758794 GO:0045685|regulation of glial cell differentiation, ! regulation of embryonic development GO:0045995 16 8 1,000 9,406E-04 0,0174461 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 9,406E-04 0,01730653 ! negative regulation of DNA binding GO:0043392 54 33 2,000 9,53E-04 0,01739665 ! negative regulation of growth GO:0045926 123 75 3,000 1,002E-03 0,01815036 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 1,041E-03 0,01870207 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 1,041E-03 0,0185571 ! regulation of protein transport GO:0051223 114 76 3,000 1,053E-03 0,01863268 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 3,000 1,106E-03 0,0194162 ! regulation of developmental growth GO:0048638 13 9 1,000 1,205E-03 0,02099032 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 1,205E-03 0,02083249 ! regulation of glycolysis GO:0006110 15 9 1,000 1,205E-03 0,02067703 ! lung alveolus development GO:0048286 17 9 1,000 1,205E-03 0,02052386 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,205E-03 0,02037295 GO:0006600|creatine metabolic process, ! motor axon guidance GO:0008045 14 9 1,000 1,205E-03 0,02022425 ! negative regulation of binding GO:0051100 58 36 2,000 1,231E-03 0,02052208 ! regulation of T cell proliferation GO:0042129 58 38 2,000 1,442E-03 0,02386821 ! mesenchymal cell development GO:0014031 64 38 2,000 1,442E-03 0,02369773 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! hippocampus development GO:0021766 19 10 1,000 1,5E-03 0,02446881 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,5E-03 0,0242965 ! blood vessel remodeling GO:0001974 21 10 1,000 1,5E-03 0,02412659 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 1,5E-03 0,02395904 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,5E-03 0,02379381 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,5E-03 0,02363084 ! response to X-ray GO:0010165 16 10 1,000 1,5E-03 0,02347008 ! regulation of bone resorption GO:0045124 24 10 1,000 1,5E-03 0,0233115 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,5E-03 0,02315505 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 1,5E-03 0,02300068 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of DNA metabolic process GO:0051052 135 85 3,000 1,596E-03 0,02431388 ! regulation of protein localization GO:0032880 132 85 3,000 1,596E-03 0,02415392 ! T cell differentiation GO:0030217 65 40 2,000 1,675E-03 0,02518034 ! positive regulation of protein transport GO:0051222 55 40 2,000 1,675E-03 0,02501683 ! regulation of T cell differentiation GO:0045580 59 41 2,000 1,8E-03 0,02670368 ! virus-host interaction GO:0019048 17 11 1,000 1,826E-03 0,02692696 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 1,826E-03 0,02675545 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,826E-03 0,02658611 ! regulation of mRNA processing GO:0050684 18 11 1,000 1,826E-03 0,02641891 ! focal adhesion formation GO:0048041 24 11 1,000 1,826E-03 0,02625379 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,826E-03 0,02609072 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 1,826E-03 0,02592967 ! nitric oxide metabolic process GO:0046209 14 11 1,000 1,826E-03 0,02577059 GO:0006809|nitric oxide biosynthetic process, ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,826E-03 0,02561345 ! activation of caspase activity GO:0006919 65 43 2,000 2,066E-03 0,02879471 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 2,183E-03 0,03024932 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 2,183E-03 0,03006819 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 2,183E-03 0,02988921 ! peptidyl-lysine modification GO:0018205 18 12 1,000 2,183E-03 0,02971235 ! response to gamma radiation GO:0010332 20 12 1,000 2,183E-03 0,02953757 ! regulation of mRNA stability GO:0043488 27 12 1,000 2,183E-03 0,02936484 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 2,183E-03 0,02919411 ! regulation of cell projection organization GO:0031344 83 44 2,000 2,207E-03 0,02934746 ! regulation of binding GO:0051098 151 95 3,000 2,4E-03 0,03172096 ! response to UV GO:0009411 75 46 2,000 2,509E-03 0,0329712 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,57E-03 0,03358869 ! endocrine pancreas development GO:0031018 19 13 1,000 2,57E-03 0,03339892 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 2,57E-03 0,03321129 ! regulation of cellular pH GO:0030641 20 13 1,000 2,57E-03 0,03302575 ! regulation of RNA stability GO:0043487 28 13 1,000 2,57E-03 0,03284227 ! negative regulation of immune system process GO:0002683 73 47 2,000 2,668E-03 0,0339072 ! positive regulation of caspase activity GO:0043280 72 48 2,000 2,834E-03 0,03581631 GO:0010952|positive regulation of peptidase activity, ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 2,834E-03 0,03562059 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,987E-03 0,03733935 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2,987E-03 0,03713751 ! limbic system development GO:0021761 25 14 1,000 2,987E-03 0,03693785 ! cellular response to starvation GO:0009267 21 14 1,000 2,987E-03 0,03674032 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 2,987E-03 0,03654489 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,987E-03 0,03635153 ! G1/S transition checkpoint GO:0031575 33 14 1,000 2,987E-03 0,03616021 ! synaptic transmission, cholinergic GO:0007271 21 14 1,000 2,987E-03 0,03597089 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,987E-03 0,03578354 ! positive regulation of growth GO:0045927 67 50 2,000 3,185E-03 0,03795008 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 3,434E-03 0,04070648 ! lipid phosphorylation GO:0046834 23 15 1,000 3,434E-03 0,04049772 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 3,434E-03 0,0402911 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 3,434E-03 0,04008658 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 3,434E-03 0,03988412 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 3,434E-03 0,0396837 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 3,434E-03 0,03948528 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 3,434E-03 0,03928884 ! aging GO:0007568 79 52 2,000 3,56E-03 0,04053817 ! cell projection assembly GO:0030031 76 53 2,000 3,758E-03 0,04257756 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 3,909E-03 0,04407178 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,909E-03 0,04385679 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,909E-03 0,04364389 GO:0030968|endoplasmic reticulum unfolded protein response, ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 3,909E-03 0,04343305 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 3,909E-03 0,04322424 ! negative regulation of translation GO:0017148 22 16 1,000 3,909E-03 0,04301743 ! regulation of protein complex assembly GO:0043254 81 54 2,000 3,962E-03 0,04339472 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 4,39E-03 0,04785843 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 4,39E-03 0,04763269 ! inactivation of MAPK activity GO:0000188 27 17 1,000 4,413E-03 0,04765441 ! cell-substrate junction assembly GO:0007044 39 17 1,000 4,413E-03 0,04743172 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 4,413E-03 0,04721111 ! actin filament bundle formation GO:0051017 26 17 1,000 4,413E-03 0,04699254 ! neuromuscular junction development GO:0007528 23 17 1,000 4,413E-03 0,04677598 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 4,413E-03 0,04656141 ! peptidyl-serine modification GO:0018209 27 17 1,000 4,413E-03 0,04634881 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 4,413E-03 0,04613813 ! positive regulation of DNA replication GO:0045740 29 18 1,000 4,946E-03 0,05147282 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 4,946E-03 0,05124096 ! pancreas development GO:0031016 26 18 1,000 4,946E-03 0,05101118 ! pigmentation during development GO:0048066 31 18 1,000 4,946E-03 0,05078345 ! somitogenesis GO:0001756 24 18 1,000 4,946E-03 0,05055775 ! cellular response to nutrient levels GO:0031669 27 18 1,000 4,946E-03 0,05033404 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 4,946E-03 0,0501123 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 4,946E-03 0,04989251 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 4,946E-03 0,04967464 ! activation of MAPK activity GO:0000187 84 59 2,000 5,084E-03 0,05083899 ! lung development GO:0030324 94 59 2,000 5,084E-03 0,05061891 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 5,507E-03 0,05459121 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 5,507E-03 0,05435691 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 5,507E-03 0,05412462 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 5,507E-03 0,0538943 GO:0010675|regulation of cellular carbohydrate metabolic process, ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 5,507E-03 0,05366593 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 5,507E-03 0,05343949 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 5,507E-03 0,05321496 ! apoptotic nuclear changes GO:0030262 24 19 1,000 5,507E-03 0,0529923 ! response to starvation GO:0042594 30 19 1,000 5,507E-03 0,0527715 ! sex determination GO:0007530 29 19 1,000 5,507E-03 0,05255253 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 5,507E-03 0,05233537 ! leukotriene biosynthetic process GO:0019370 26 19 1,000 5,507E-03 0,05212 GO:0043450|alkene biosynthetic process, ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 5,507E-03 0,05190639 ! meiosis GO:0007126 96 61 2,000 5,581E-03 0,05239079 GO:0051327|M phase of meiotic cell cycle, ! respiratory tube development GO:0030323 99 62 2,000 5,84E-03 0,05459909 ! meiotic cell cycle GO:0051321 97 62 2,000 5,84E-03 0,05437804 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 6,095E-03 0,05652662 ! pallium development GO:0021543 38 20 1,000 6,095E-03 0,05629961 ! positive regulation of locomotion GO:0040017 35 20 1,000 6,095E-03 0,05607441 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 31 20 1,000 6,095E-03 0,05585101 ! cell cycle checkpoint GO:0000075 108 64 2,000 6,379E-03 0,0582211 ! respiratory system development GO:0060541 100 64 2,000 6,379E-03 0,05799097 ! adaptive immune response GO:0002250 94 64 2,000 6,379E-03 0,05776266 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 6,711E-03 0,06052956 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 6,711E-03 0,06029312 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 6,711E-03 0,06005851 ! protein amino acid acylation GO:0043543 37 21 1,000 6,711E-03 0,05982573 ! regulation of chemotaxis GO:0050920 36 21 1,000 6,711E-03 0,05959474 ! dendrite development GO:0016358 35 21 1,000 6,711E-03 0,05936553 ! cell aging GO:0007569 32 21 1,000 6,711E-03 0,05913808 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 6,711E-03 0,05891236 ! leukotriene metabolic process GO:0006691 28 21 1,000 6,711E-03 0,05868836 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 7,354E-03 0,06406702 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 7,354E-03 0,06382526 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 7,354E-03 0,06358531 ! vasculogenesis GO:0001570 33 22 1,000 7,354E-03 0,06334716 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 7,354E-03 0,06311079 GO:0010810|regulation of cell-substrate adhesion, ! regulation of behavior GO:0050795 38 22 1,000 7,354E-03 0,06287618 ! cellular alkene metabolic process GO:0043449 29 22 1,000 7,354E-03 0,06264331 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 8,023E-03 0,0680952 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 8,023E-03 0,06784485 ! myelination GO:0042552 35 23 1,000 8,023E-03 0,06759633 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 8,023E-03 0,06734963 ! negative regulation of DNA replication GO:0008156 35 23 1,000 8,023E-03 0,06710472 ! interaction with host GO:0051701 37 23 1,000 8,023E-03 0,06686159 ! regulation of catabolic process GO:0009894 106 70 2,000 8,171E-03 0,0678453 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 8,495E-03 0,07028592 ! lymphocyte differentiation GO:0030098 113 71 2,000 8,495E-03 0,070034 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 8,719E-03 0,07162356 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 8,719E-03 0,07136867 ! mitochondrial membrane organization GO:0007006 39 24 1,000 8,719E-03 0,07111559 ! response to toxin GO:0009636 38 24 1,000 8,719E-03 0,07086429 ! base-excision repair GO:0006284 31 24 1,000 8,719E-03 0,07061477 ! response to hypoxia GO:0001666 132 72 2,000 8,827E-03 0,07123876 ! negative regulation of organelle organization GO:0010639 115 72 2,000 8,827E-03 0,07098967 ! mitochondrion organization GO:0007005 104 73 2,000 9,167E-03 0,07346311 ! regulation of chromosome organization GO:0033044 35 25 1,000 9,441E-03 0,07540044 ! positive regulation of nuclear division GO:0051785 39 25 1,000 9,441E-03 0,07513954 GO:0045840|positive regulation of mitosis, ! response to oxygen levels GO:0070482 137 74 2,000 9,514E-03 0,07545574 ! protein import into nucleus GO:0006606 118 74 2,000 9,514E-03 0,07519644 ! nuclear import GO:0051170 121 75 2,000 9,869E-03 0,07773245 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,01018924 0,07998378 ! regulation of pH GO:0006885 36 26 1,000 0,01018924 0,07971173 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01018924 0,07944152 ! response to unfolded protein GO:0006986 99 76 2,000 0,01023092 0,07949702 ! response to ionizing radiation GO:0010212 47 27 1,000 0,01096244 0,08489433 ! negative regulation of protein transport GO:0051224 49 27 1,000 0,01096244 0,08460945 ! T cell activation GO:0042110 134 79 2,000 0,0113638 0,08741385 ! protein localization in nucleus GO:0034504 133 80 2,000 0,01175686 0,09013596 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01176074 0,08986611 ! icosanoid biosynthetic process GO:0046456 42 28 1,000 0,01176074 0,08956854 ! cell junction assembly GO:0034329 56 28 1,000 0,01176074 0,08927293 ! complement activation, classical pathway GO:0006958 36 28 1,000 0,01176074 0,08897927 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,01176074 0,08868754 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 0,01176074 0,08839771 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01176074 0,08810977 GO:0008366|axon ensheathment, ! regulation of cell cycle process GO:0010564 122 81 2,000 0,01215769 0,09078795 ! response to protein stimulus GO:0051789 111 81 2,000 0,01215769 0,09049414 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01258381 0,09336376 ! telencephalon development GO:0021537 52 29 1,000 0,01258381 0,09306355 ! tissue homeostasis GO:0001894 42 29 1,000 0,01258381 0,09276527 GO:0048871|multicellular organismal homeostasis, ! regulation of cell adhesion GO:0030155 159 83 2,000 0,01298272 0,0954002 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 1,000 0,01343134 0,09838246 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01343134 0,09807014 ! response to heat GO:0009408 41 30 1,000 0,01343134 0,09775979 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01430303 0,10377593 ! mammary gland development GO:0030879 57 31 1,000 0,01430303 0,10344959 ! xenobiotic metabolic process GO:0006805 44 31 1,000 0,01430303 0,1031253 ! segmentation GO:0035282 41 31 1,000 0,01430303 0,10280303 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01430303 0,10248277 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 1,000 0,01430303 0,1021645 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,01472689 0,10486642 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,01472689 0,10454276 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,01519856 0,10755903 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,01519856 0,1072291 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,01519856 0,10690118 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01519856 0,10657526 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01519856 0,10625132 ! regulation of protein stability GO:0031647 48 32 1,000 0,01519856 0,10592935 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,01519856 0,10560932 ! regulation of neurogenesis GO:0050767 153 89 2,000 0,01564632 0,1083932 ! regulation of T cell activation GO:0050863 128 89 2,000 0,01564632 0,1080677 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,01611763 0,11098963 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,01611763 0,11065832 ! sister chromatid segregation GO:0000819 46 33 1,000 0,01611763 0,11032898 ! cell junction organization GO:0034330 63 33 1,000 0,01611763 0,1100016 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,01611763 0,10967615 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 0,01611763 0,10935262 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01611763 0,10903099 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,01611763 0,10871126 ! cytokinesis GO:0000910 52 33 1,000 0,01611763 0,10839339 ! response to virus GO:0009615 122 91 2,000 0,01659748 0,11129506 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,01705993 0,11406346 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,01705993 0,11373284 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,01705993 0,11340413 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01802516 0,11947513 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01802516 0,11913182 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01802516 0,11879046 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 0,01802516 0,11845106 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01901303 0,12458684 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,01901303 0,1242329 ! tissue remodeling GO:0048771 62 36 1,000 0,01901303 0,12388096 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 0,01901303 0,12353101 ! glucan metabolic process GO:0044042 49 36 1,000 0,01901303 0,12318304 GO:0006073|cellular glucan metabolic process, ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,01911479 0,12349445 ! response to light stimulus GO:0009416 153 96 2,000 0,01911479 0,12314852 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,02002325 0,12864099 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 1,000 0,02002325 0,12828266 GO:0006956|complement activation, ! amino acid activation GO:0043038 52 37 1,000 0,02002325 0,12792632 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! protein import GO:0017038 156 99 2,000 0,02072112 0,13201821 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,02072112 0,13165352 ! pigmentation GO:0043473 74 38 1,000 0,02105552 0,1334096 ! regulation of translation GO:0006417 151 100 2,000 0,02127258 0,13441468 ! Ras protein signal transduction GO:0007265 162 100 2,000 0,02127258 0,13404643 ! protein localization in organelle GO:0033365 161 100 2,000 0,02127258 0,13368018 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,02210954 0,13856116 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,02210954 0,13818463 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,02210954 0,13781015 ! synapse organization GO:0050808 55 39 1,000 0,02210954 0,13743769 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,02318504 0,14373476 ! double-strand break repair GO:0006302 67 40 1,000 0,02318504 0,14334837 ! B cell differentiation GO:0030183 62 40 1,000 0,02318504 0,14296406 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,02318504 0,14258181 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,02428173 0,14892795 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,02428173 0,14853187 ! glucose transport GO:0015758 52 41 1,000 0,02428173 0,14813788 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02428173 0,14774598 ! mitochondrial transport GO:0006839 60 42 1,000 0,02539933 0,1541384 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,02539933 0,15373278 ! cellular component disassembly GO:0022411 64 42 1,000 0,02539933 0,15332928 ! hexose transport GO:0008645 54 42 1,000 0,02539933 0,15292789 GO:0015749|monosaccharide transport, ! icosanoid metabolic process GO:0006690 61 42 1,000 0,02539933 0,1525286 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,02539933 0,15213139 ! regulation of cell shape GO:0008360 78 42 1,000 0,02539933 0,15173625 ! positive regulation of binding GO:0051099 59 43 1,000 0,02653755 0,15812532 ! regulation of action potential GO:0001508 71 44 1,000 0,02769613 0,16460233 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,02769613 0,16417809 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,02887478 0,17072495 ! regulation of translational initiation GO:0006446 64 45 1,000 0,02887478 0,17028719 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,02887478 0,16985167 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02911707 0,17083997 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02911707 0,17040526 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02911707 0,16997276 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02911707 0,16954245 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02911707 0,16911431 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02911707 0,16868833 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02911707 0,16826449 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02911707 0,16784278 ! sleep GO:0030431 11 5 0,000 0,02911707 0,16742317 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02911707 0,16700566 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02911707 0,16659022 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02911707 0,16617684 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02911707 0,16576552 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02911707 0,16535622 ! tongue development GO:0043586 6 5 0,000 0,02911707 0,16494894 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02911707 0,16454366 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02911707 0,16414036 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02911707 0,16373904 ! cobalt ion transport GO:0006824 9 5 0,000 0,02911707 0,16333968 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02911707 0,16294226 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02911707 0,16254677 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02911707 0,16215319 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02911707 0,16176152 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02911707 0,16137173 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02911707 0,16098382 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02911707 0,16059777 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02911707 0,16021356 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02911707 0,15983119 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02911707 0,15945064 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02911707 0,1590719 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02911707 0,15869495 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02911707 0,15831978 ! malate metabolic process GO:0006108 7 5 0,000 0,02911707 0,15794639 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02911707 0,15757475 ! behavioral response to pain GO:0048266 7 5 0,000 0,02911707 0,15720486 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02911707 0,15683669 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02911707 0,15647025 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02911707 0,15610552 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02911707 0,15574248 ! mating behavior GO:0007617 6 5 0,000 0,02911707 0,15538113 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02911707 0,15502145 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02911707 0,15466344 ! rhythmic behavior GO:0007622 12 5 0,000 0,02911707 0,15430707 ! copulation GO:0007620 7 5 0,000 0,02911707 0,15395234 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02911707 0,15359924 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02911707 0,15324775 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02911707 0,15289787 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02911707 0,15254959 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02911707 0,15220288 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02911707 0,15185775 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02911707 0,15151418 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02911707 0,15117216 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02911707 0,15083169 ! response to protozoan GO:0001562 9 5 0,000 0,02911707 0,15049274 ! lymph vessel development GO:0001945 7 5 0,000 0,02911707 0,15015531 ! endochondral ossification GO:0001958 12 5 0,000 0,02911707 0,14981939 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02911707 0,14948497 ! parathyroid gland development GO:0060017 8 5 0,000 0,02911707 0,14915205 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02911707 0,1488206 ! anagen GO:0042640 6 5 0,000 0,02911707 0,14849062 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02911707 0,1481621 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02911707 0,14783503 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02911707 0,1475094 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02911707 0,1471852 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02911707 0,14686243 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02911707 0,14654107 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02911707 0,14622111 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02911707 0,14590255 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02911707 0,14558537 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02911707 0,14526956 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02911707 0,14495513 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02911707 0,14464205 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02911707 0,14433032 ! ovulation GO:0030728 6 5 0,000 0,02911707 0,14401993 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02911707 0,14371088 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02911707 0,14340314 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,02911707 0,14309673 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02911707 0,14279162 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02911707 0,1424878 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02911707 0,14218528 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02911707 0,14188404 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02911707 0,14158408 ! polyol catabolic process GO:0046174 7 5 0,000 0,02911707 0,14128538 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02911707 0,14098793 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02911707 0,14069174 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02911707 0,14039679 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02911707 0,14010307 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02911707 0,13981058 ! urea metabolic process GO:0019627 6 5 0,000 0,02911707 0,13951931 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02911707 0,13922925 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02911707 0,13894039 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02911707 0,13865273 ! neutrophil activation GO:0042119 5 5 0,000 0,02911707 0,13836626 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02911707 0,13808097 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02911707 0,13779685 ! response to food GO:0032094 5 5 0,000 0,02911707 0,1375139 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02911707 0,13723211 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02911707 0,13695147 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02911707 0,13667198 ! forebrain neuron development GO:0021884 7 5 0,000 0,02911707 0,13639362 ! melanosome organization GO:0032438 7 5 0,000 0,02911707 0,1361164 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02911707 0,1358403 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02911707 0,13556532 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02911707 0,13529145 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02911707 0,13501869 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02911707 0,13474702 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02911707 0,13447644 ! nucleoside transport GO:0015858 6 5 0,000 0,02911707 0,13420695 ! nucleoside salvage GO:0043174 7 5 0,000 0,02911707 0,13393854 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02911707 0,13367119 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02911707 0,13340492 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02911707 0,1331397 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02911707 0,13287553 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02911707 0,13261241 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02911707 0,13235033 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02911707 0,13208929 ! depyrimidination GO:0045008 8 5 0,000 0,02911707 0,13182927 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02911707 0,13157027 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02911707 0,13131229 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02911707 0,13105532 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02911707 0,13079935 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02911707 0,13054438 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02911707 0,13029041 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02911707 0,13003741 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02911707 0,1297854 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02911707 0,12953437 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02911707 0,1292843 ! centrosome duplication GO:0051298 5 5 0,000 0,02911707 0,1290352 ! response to UV-C GO:0010225 6 5 0,000 0,02911707 0,12878705 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02911707 0,12853986 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02911707 0,12829362 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02911707 0,12804831 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02911707 0,12780395 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02911707 0,12756051 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02911707 0,127318 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02911707 0,12707641 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02911707 0,12683574 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02911707 0,12659597 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02911707 0,12635711 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02911707 0,12611915 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02911707 0,12588208 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02911707 0,12564591 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02911707 0,12541061 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02911707 0,1251762 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02911707 0,12494266 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02911707 0,12471 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02911707 0,12447819 ! neural tube patterning GO:0021532 6 5 0,000 0,02911707 0,12424725 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02911707 0,12401716 ! histone demethylation GO:0016577 9 5 0,000 0,02911707 0,12378793 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02911707 0,12355954 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02911707 0,12333199 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02911707 0,12310527 ! enteric nervous system development GO:0048484 8 5 0,000 0,02911707 0,12287939 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02911707 0,12265434 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02911707 0,12243011 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02911707 0,12220669 ! transcription termination GO:0006353 8 5 0,000 0,02911707 0,1219841 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02911707 0,12176231 ! plasminogen activation GO:0031639 5 5 0,000 0,02911707 0,12154132 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02911707 0,12132114 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02911707 0,12110175 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02911707 0,12088316 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02911707 0,12066535 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02911707 0,12044832 ! apical protein localization GO:0045176 6 5 0,000 0,02911707 0,12023208 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02911707 0,12001661 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02911707 0,11980191 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02911707 0,11958798 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02911707 0,11937481 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02911707 0,1191624 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02911707 0,11895074 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02911707 0,11873984 ! glial cell migration GO:0008347 10 5 0,000 0,02911707 0,11852968 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02911707 0,11832026 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02911707 0,11811158 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02911707 0,11790364 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02911707 0,11769643 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02911707 0,11748994 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02911707 0,11728418 ! neural plate development GO:0001840 6 5 0,000 0,02911707 0,11707914 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02911707 0,11687481 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02911707 0,1166712 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02911707 0,11646829 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02911707 0,11626609 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02911707 0,11606459 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02911707 0,11586379 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02911707 0,11566368 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02911707 0,11546426 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02911707 0,11526552 ! spindle assembly GO:0051225 5 5 0,000 0,02911707 0,11506747 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02911707 0,1148701 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02911707 0,1146734 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02911707 0,11447738 ! organ regeneration GO:0031100 7 5 0,000 0,02911707 0,11428203 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02911707 0,11408734 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02911707 0,11389331 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02911707 0,11369995 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02911707 0,11350723 GO:0055081|anion homeostasis, ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,03007324 0,11703631 ! unsaturated fatty acid metabolic process GO:0033559 66 46 1,000 0,03007324 0,11683862 ! histone modification GO:0016570 68 46 1,000 0,03007324 0,11664159 ! endocrine system development GO:0035270 83 47 1,000 0,03129124 0,12116136 ! covalent chromatin modification GO:0016569 75 47 1,000 0,03129124 0,12095773 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,03129124 0,12075478 ! response to temperature stimulus GO:0009266 62 48 1,000 0,0325285 0,12531919 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,0325285 0,12510963 ! heart morphogenesis GO:0003007 65 48 1,000 0,0325285 0,12490076 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,0325285 0,1246926 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,0325285 0,12448512 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,03378477 0,12907803 ! tRNA transcription GO:0009304 11 6 0,000 0,03483893 0,13288482 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03483893 0,13266481 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03483893 0,13244553 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03483893 0,13222697 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03483893 0,13200914 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03483893 0,13179202 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03483893 0,13157561 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03483893 0,13135991 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03483893 0,13114492 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03483893 0,13093063 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03483893 0,13071704 ! prostate gland development GO:0030850 9 6 0,000 0,03483893 0,13050415 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03483893 0,13029194 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03483893 0,13008043 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03483893 0,1298696 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03483893 0,12965946 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03483893 0,12944999 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03483893 0,1292412 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03483893 0,12903308 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03483893 0,12882564 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03483893 0,12861885 ! neuron adhesion GO:0007158 9 6 0,000 0,03483893 0,12841273 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03483893 0,12820727 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03483893 0,12800247 ! signal peptide processing GO:0006465 8 6 0,000 0,03483893 0,12779832 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03483893 0,12759482 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03483893 0,12739196 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03483893 0,12718975 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03483893 0,12698819 ! opsonization GO:0008228 8 6 0,000 0,03483893 0,12678726 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03483893 0,12658696 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03483893 0,1263873 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03483893 0,12618826 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03483893 0,12598985 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03483893 0,12579207 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03483893 0,1255949 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03483893 0,12539835 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03483893 0,12520241 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03483893 0,12500709 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03483893 0,12481238 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03483893 0,12461827 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03483893 0,12442476 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03483893 0,12423185 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03483893 0,12403954 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03483893 0,12384783 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03483893 0,12365671 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03483893 0,12346617 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03483893 0,12327622 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03483893 0,12308686 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03483893 0,12289808 ! thymic T cell selection GO:0045061 12 6 0,000 0,03483893 0,12270987 ! protein lipoylation GO:0009249 10 6 0,000 0,03483893 0,12252224 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03483893 0,12233518 ! pigment granule organization GO:0048753 11 6 0,000 0,03483893 0,1221487 ! drug transport GO:0015893 6 6 0,000 0,03483893 0,12196278 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03483893 0,12177742 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03483893 0,12159263 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03483893 0,1214084 ! histidine metabolic process GO:0006547 6 6 0,000 0,03483893 0,12122473 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03483893 0,12104161 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03483893 0,12085904 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03483893 0,12067703 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03483893 0,12049556 ! adenohypophysis development GO:0021984 10 6 0,000 0,03483893 0,12031463 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03483893 0,12013425 ! hyperosmotic response GO:0006972 8 6 0,000 0,03483893 0,11995441 ! microtubule nucleation GO:0007020 10 6 0,000 0,03483893 0,11977511 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03483893 0,11959634 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03483893 0,1194181 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03483893 0,1192404 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03483893 0,11906322 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03483893 0,11888657 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,03483893 0,11871044 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03483893 0,11853483 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03483893 0,11835974 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03483893 0,11818517 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03483893 0,11801111 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03483893 0,11783757 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03483893 0,11766453 ! neuron apoptosis GO:0051402 8 6 0,000 0,03483893 0,117492 ! organic alcohol transport GO:0015850 9 6 0,000 0,03483893 0,11731998 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03483893 0,11714846 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03483893 0,11697744 ! carnitine transport GO:0015879 8 6 0,000 0,03483893 0,11680692 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03483893 0,11663689 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03483893 0,11646736 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03483893 0,11629832 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03483893 0,11612978 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03483893 0,11596172 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03483893 0,11579414 ! parturition GO:0007567 12 6 0,000 0,03483893 0,11562705 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03483893 0,11546044 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03483893 0,11529431 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03483893 0,11512866 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03483893 0,11496348 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03483893 0,11479878 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03483893 0,11463454 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03483893 0,11447078 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03483893 0,11430748 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03483893 0,11414465 ! astrocyte development GO:0014002 14 6 0,000 0,03483893 0,11398228 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03483893 0,11382038 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03483893 0,11365893 ! interaction with symbiont GO:0051702 8 6 0,000 0,03483893 0,11349794 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03483893 0,11333741 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03483893 0,11317732 ! eating behavior GO:0042755 6 6 0,000 0,03483893 0,11301769 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03483893 0,11285851 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03483893 0,11269978 ! response to copper ion GO:0046688 9 6 0,000 0,03483893 0,1125415 ! DNA topological change GO:0006265 8 6 0,000 0,03483893 0,11238365 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03483893 0,11222625 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03483893 0,11206929 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03483893 0,11191277 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03483893 0,11175669 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03483893 0,11160104 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03483893 0,11144582 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03483893 0,11129104 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03483893 0,11113668 ! gas homeostasis GO:0033483 11 6 0,000 0,03483893 0,11098275 ! hair follicle maturation GO:0048820 7 6 0,000 0,03483893 0,11082925 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03483893 0,11067617 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03483893 0,11052351 ! Schwann cell development GO:0014044 14 6 0,000 0,03483893 0,11037127 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03483893 0,11021946 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03483893 0,11006806 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03483893 0,10991707 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03483893 0,1097665 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03483893 0,10961634 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03483893 0,10946659 ! histone ubiquitination GO:0016574 7 6 0,000 0,03483893 0,10931725 ! regulation of meiosis GO:0040020 10 6 0,000 0,03483893 0,10916832 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03483893 0,10901979 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03483893 0,10887167 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03483893 0,10872394 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03483893 0,10857662 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03483893 0,1084297 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03483893 0,10828317 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03483893 0,10813704 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03483893 0,1079913 ! receptor internalization GO:0031623 9 6 0,000 0,03483893 0,10784596 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03483893 0,107701 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03483893 0,10755644 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03483893 0,10741226 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03483893 0,10726847 ! protein deubiquitination GO:0016579 8 6 0,000 0,03483893 0,10712506 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03483893 0,10698204 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03483893 0,10683939 ! axonal fasciculation GO:0007413 9 6 0,000 0,03483893 0,10669713 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03483893 0,10655525 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03483893 0,10641374 ! midbrain development GO:0030901 6 6 0,000 0,03483893 0,10627261 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03483893 0,10613185 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03483893 0,10599146 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03483893 0,10585145 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03483893 0,1057118 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03483893 0,10557252 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03483893 0,10543361 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03483893 0,10529507 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03483893 0,10515688 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03483893 0,10501906 ! adult feeding behavior GO:0008343 6 6 0,000 0,03483893 0,1048816 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03483893 0,1047445 ! blastocyst growth GO:0001832 15 6 0,000 0,03483893 0,10460776 ! pigment granule transport GO:0051904 12 6 0,000 0,03483893 0,10447138 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03483893 0,10433535 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03483893 0,10419967 ! catecholamine transport GO:0051937 7 6 0,000 0,03483893 0,10406434 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03483893 0,10392937 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03483893 0,10379475 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03483893 0,10366047 ! protein prenylation GO:0018342 10 6 0,000 0,03483893 0,10352654 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03483893 0,10339296 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03483893 0,10325972 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03483893 0,10312683 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03483893 0,10299427 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,03505978 0,10351412 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,03505978 0,10338141 ! lipid modification GO:0030258 73 50 1,000 0,03505978 0,10324904 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,03505978 0,10311701 ! muscle fiber development GO:0048747 74 51 1,000 0,03635328 0,10678485 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,03635328 0,10664864 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,03635328 0,10651279 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,03635328 0,10637727 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,037665 0,11007559 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,03899468 0,11381697 ! regulation of mitosis GO:0007088 84 54 1,000 0,04034209 0,11760052 GO:0051783|regulation of nuclear division, ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,04034209 0,11745166 ! DNA catabolic process GO:0006308 67 54 1,000 0,04034209 0,11730317 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,04034209 0,11715506 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,0405274 0,11754478 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0405274 0,11739674 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0405274 0,11724907 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0405274 0,11710177 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0405274 0,11695485 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0405274 0,11680829 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0405274 0,11666209 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0405274 0,11651626 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0405274 0,1163708 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0405274 0,1162257 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0405274 0,11608096 ! reproductive behavior GO:0019098 12 7 0,000 0,0405274 0,11593658 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0405274 0,11579256 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0405274 0,1156489 ! oligopeptide transport GO:0006857 11 7 0,000 0,0405274 0,11550559 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0405274 0,11536264 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0405274 0,11522004 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0405274 0,11507779 ! RNA methylation GO:0001510 11 7 0,000 0,0405274 0,1149359 ! pericardium development GO:0060039 8 7 0,000 0,0405274 0,11479435 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0405274 0,11465315 ! fibril organization GO:0043206 13 7 0,000 0,0405274 0,1145123 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0405274 0,11437179 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0405274 0,11423163 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0405274 0,11409181 ! lipoprotein transport GO:0042953 9 7 0,000 0,0405274 0,11395234 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0405274 0,1138132 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0405274 0,1136744 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0405274 0,11353595 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0405274 0,11339782 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0405274 0,11326004 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0405274 0,11312259 ! chemosensory behavior GO:0007635 9 7 0,000 0,0405274 0,11298547 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0405274 0,11284868 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0405274 0,11271223 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0405274 0,1125761 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0405274 0,1124403 ! reflex GO:0060004 12 7 0,000 0,0405274 0,11230483 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0405274 0,11216969 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0405274 0,11203487 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0405274 0,11190037 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0405274 0,1117662 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0405274 0,11163235 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0405274 0,11149882 ! spinal cord patterning GO:0021511 7 7 0,000 0,0405274 0,11136561 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0405274 0,11123271 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0405274 0,11110013 ! adrenal gland development GO:0030325 17 7 0,000 0,0405274 0,11096787 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0405274 0,11083592 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0405274 0,11070429 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0405274 0,11057297 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0405274 0,11044196 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0405274 0,11031126 ! endosome organization GO:0007032 10 7 0,000 0,0405274 0,11018086 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0405274 0,11005078 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0405274 0,109921 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0405274 0,10979153 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0405274 0,10966237 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0405274 0,1095335 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0405274 0,10940494 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0405274 0,10927668 ! galactose metabolic process GO:0006012 10 7 0,000 0,0405274 0,10914873 ! vesicle fusion GO:0006906 15 7 0,000 0,0405274 0,10902107 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0405274 0,10889371 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0405274 0,10876664 ! organ growth GO:0035265 11 7 0,000 0,0405274 0,10863987 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0405274 0,1085134 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0405274 0,10838722 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0405274 0,10826134 ! retinol metabolic process GO:0042572 9 7 0,000 0,0405274 0,10813574 ! behavioral fear response GO:0001662 13 7 0,000 0,0405274 0,10801044 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0405274 0,10788543 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0405274 0,10776071 ! rRNA modification GO:0000154 12 7 0,000 0,0405274 0,10763627 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0405274 0,10751212 ! response to UV-B GO:0010224 11 7 0,000 0,0405274 0,10738826 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0405274 0,10726469 ! intermediate filament organization GO:0045109 11 7 0,000 0,0405274 0,10714139 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0405274 0,10701838 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0405274 0,10689566 ! fibrinolysis GO:0042730 9 7 0,000 0,0405274 0,10677321 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0405274 0,10665104 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0405274 0,10652916 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0405274 0,10640755 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0405274 0,10628622 ! response to tropane GO:0014073 13 7 0,000 0,0405274 0,10616516 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0405274 0,10604438 ! melanosome localization GO:0032400 10 7 0,000 0,0405274 0,10592388 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0405274 0,10580365 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0405274 0,10568369 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0405274 0,105564 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0405274 0,10544458 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0405274 0,10532544 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0405274 0,10520656 ! mast cell activation GO:0045576 9 7 0,000 0,0405274 0,10508795 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0405274 0,10496961 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0405274 0,10485153 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0405274 0,10473372 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0405274 0,10461617 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0405274 0,10449889 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0405274 0,10438187 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0405274 0,10426511 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0405274 0,10414862 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0405274 0,10403238 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0405274 0,1039164 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0405274 0,10380068 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0405274 0,10368522 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0405274 0,10357001 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0405274 0,10345506 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0405274 0,10334037 ! diuresis GO:0030146 12 7 0,000 0,0405274 0,10322593 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0405274 0,10311174 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0405274 0,1029978 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0405274 0,10288412 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0405274 0,10277069 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0405274 0,1026575 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0405274 0,10254457 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0405274 0,10243188 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0405274 0,10231944 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0405274 0,10220725 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0405274 0,1020953 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0405274 0,1019836 ! lymph node development GO:0048535 9 7 0,000 0,0405274 0,10187214 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0405274 0,10176093 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0405274 0,10164996 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0405274 0,10153923 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0405274 0,10142874 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0405274 0,10131849 ! ATP catabolic process GO:0006200 10 7 0,000 0,0405274 0,10120848 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0405274 0,10109871 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0405274 0,10098918 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0405274 0,10087988 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0405274 0,10077082 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0405274 0,100662 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0405274 0,10055341 ! muscle adaptation GO:0043500 12 7 0,000 0,0405274 0,10044506 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0405274 0,10033693 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0405274 0,10022904 ! retina homeostasis GO:0001895 9 7 0,000 0,0405274 0,10012139 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0405274 0,10001396 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0405274 0,09990677 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0405274 0,0997998 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0405274 0,09969306 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0405274 0,09958655 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0405274 0,09948027 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0405274 0,09937421 ! carbohydrate transport GO:0008643 74 57 1,000 0,04448812 0,10896983 ! chromosome segregation GO:0007059 83 57 1,000 0,04448812 0,10885391 ! viral reproductive process GO:0022415 87 58 1,000 0,04590391 0,11219872 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,04590391 0,11207962 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,04590391 0,11196076 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04618266 0,1125213 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04618266 0,11240223 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,04618266 0,11228342 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04618266 0,11216485 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04618266 0,11204653 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04618266 0,11192846 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04618266 0,11181064 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04618266 0,11169307 ! phosphate transport GO:0006817 10 8 0,000 0,04618266 0,11157575 ! N-glycan processing GO:0006491 12 8 0,000 0,04618266 0,11145867 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04618266 0,11134184 ! UTP metabolic process GO:0046051 8 8 0,000 0,04618266 0,11122525 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04618266 0,1111089 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04618266 0,1109928 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04618266 0,11087694 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04618266 0,11076133 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04618266 0,11064595 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,04618266 0,11053081 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04618266 0,11041592 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,04618266 0,11030126 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04618266 0,11018684 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04618266 0,11007265 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04618266 0,10995871 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04618266 0,109845 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04618266 0,10973152 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04618266 0,10961828 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04618266 0,10950527 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04618266 0,10939249 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04618266 0,10927995 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04618266 0,10916764 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04618266 0,10905556 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04618266 0,1089437 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04618266 0,10883208 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04618266 0,10872069 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04618266 0,10860952 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04618266 0,10849858 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04618266 0,10838787 ! melanin metabolic process GO:0006582 12 8 0,000 0,04618266 0,10827738 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04618266 0,10816712 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04618266 0,10805708 ! macrophage activation GO:0042116 12 8 0,000 0,04618266 0,10794727 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04618266 0,10783768 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04618266 0,10772831 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04618266 0,10761916 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04618266 0,10751023 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04618266 0,10740153 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04618266 0,10729304 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04618266 0,10718477 ! ruffle organization GO:0031529 11 8 0,000 0,04618266 0,10707672 ! osteoblast development GO:0002076 13 8 0,000 0,04618266 0,10696889 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04618266 0,10686128 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04618266 0,10675388 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04618266 0,1066467 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04618266 0,10653973 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04618266 0,10643298 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04618266 0,10632644 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04618266 0,10622011 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04618266 0,106114 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04618266 0,10600809 ! brain morphogenesis GO:0048854 20 8 0,000 0,04618266 0,1059024 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04618266 0,10579692 ! segment specification GO:0007379 10 8 0,000 0,04618266 0,10569165 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04618266 0,10558659 ! cellular extravasation GO:0045123 11 8 0,000 0,04618266 0,10548174 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04618266 0,10537709 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04618266 0,10527266 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04618266 0,10516843 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04618266 0,1050644 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04618266 0,10496058 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04618266 0,10485697 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04618266 0,10475356 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04618266 0,10465036 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04618266 0,10454735 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04618266 0,10444455 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04618266 0,10434196 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04618266 0,10423956 ! icosanoid secretion GO:0032309 12 8 0,000 0,04618266 0,10413736 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04618266 0,10403537 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04618266 0,10393357 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04618266 0,10383198 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04618266 0,10373058 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04618266 0,10362938 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04618266 0,10352837 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04618266 0,10342757 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04618266 0,10332696 ! sterol catabolic process GO:0016127 9 8 0,000 0,04618266 0,10322654 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04618266 0,10312632 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04618266 0,1030263 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04618266 0,10292646 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04618266 0,10282683 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04618266 0,10272738 ! prophase GO:0051324 11 8 0,000 0,04618266 0,10262813 ! S phase GO:0051320 8 8 0,000 0,04618266 0,10252906 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04618266 0,10243019 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04618266 0,10233151 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04618266 0,10223302 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04618266 0,10213472 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04618266 0,10203661 ! hormone catabolic process GO:0042447 13 8 0,000 0,04618266 0,10193869 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04618266 0,10184095 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04618266 0,1017434 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04618266 0,10164604 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04618266 0,10154886 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04618266 0,10145187 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,04618266 0,10135507 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04618266 0,10125845 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04618266 0,10116201 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04618266 0,10106576 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04618266 0,10096969 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04618266 0,1008738 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04618266 0,10077809 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04618266 0,10068257 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04618266 0,10058723 ! actin filament organization GO:0007015 95 59 1,000 0,04733619 0,10300212 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,04878472 0,10605375 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,04878472 0,1059536 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,05024926 0,10903142 ! fatty acid biosynthetic process GO:0006633 92 61 1,000 0,05024926 0,10892866 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,05024926 0,10882609 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,05172958 0,11192666 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,05180491 0,11198429 ! telencephalon cell migration GO:0022029 16 9 0,000 0,05180491 0,11187914 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,05180491 0,11177419 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,05180491 0,11166943 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,05180491 0,11156487 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,05180491 0,11146051 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05180491 0,11135634 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,05180491 0,11125237 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,05180491 0,11114859 ! GTP metabolic process GO:0046039 9 9 0,000 0,05180491 0,111045 ! elastic fiber assembly GO:0048251 13 9 0,000 0,05180491 0,11094161 ! social behavior GO:0035176 14 9 0,000 0,05180491 0,1108384 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,05180491 0,11073539 ! artery development GO:0060840 19 9 0,000 0,05180491 0,11063258 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,05180491 0,11052995 ! response to pain GO:0048265 16 9 0,000 0,05180491 0,11042751 ! protein complex disassembly GO:0043241 17 9 0,000 0,05180491 0,11032526 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,05180491 0,11022321 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,05180491 0,11012134 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,05180491 0,11001965 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,05180491 0,10991816 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,05180491 0,10981685 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,05180491 0,10971573 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,05180491 0,1096148 ! ventral spinal cord development GO:0021517 11 9 0,000 0,05180491 0,10951405 ! protein targeting to ER GO:0045047 19 9 0,000 0,05180491 0,10941348 ! T cell selection GO:0045058 18 9 0,000 0,05180491 0,10931311 ! endoderm development GO:0007492 12 9 0,000 0,05180491 0,10921291 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,05180491 0,1091129 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,05180491 0,10901307 ! arginine catabolic process GO:0006527 10 9 0,000 0,05180491 0,10891342 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,05180491 0,10881396 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,05180491 0,10871468 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,05180491 0,10861557 ! V(D)J recombination GO:0033151 12 9 0,000 0,05180491 0,10851665 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,05180491 0,10841791 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,05180491 0,10831935 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,05180491 0,10822097 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05180491 0,10812276 ! mannose metabolic process GO:0006013 9 9 0,000 0,05180491 0,10802474 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,05180491 0,10792689 ! receptor clustering GO:0043113 15 9 0,000 0,05180491 0,10782922 ! epithelial cell development GO:0002064 10 9 0,000 0,05180491 0,10773172 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,05180491 0,1076344 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,05180491 0,10753726 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,05180491 0,10744029 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,05180491 0,1073435 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,05180491 0,10724688 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,05180491 0,10715044 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,05180491 0,10705416 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,05180491 0,10695807 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,05180491 0,10686214 ! blastoderm segmentation GO:0007350 11 9 0,000 0,05180491 0,10676638 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,05180491 0,1066708 ! DNA ligation GO:0006266 14 9 0,000 0,05180491 0,10657539 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,05180491 0,10648015 ! response to amine stimulus GO:0014075 13 9 0,000 0,05180491 0,10638508 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,05180491 0,10629017 ! erythrocyte development GO:0048821 11 9 0,000 0,05180491 0,10619544 ! renal water homeostasis GO:0003091 14 9 0,000 0,05180491 0,10610088 ! postreplication repair GO:0006301 11 9 0,000 0,05180491 0,10600648 ! mRNA cleavage GO:0006379 13 9 0,000 0,05180491 0,10591225 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,05180491 0,10581819 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,05180491 0,1057243 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,05180491 0,10563057 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,05180491 0,10553701 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,05180491 0,10544361 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,05180491 0,10535038 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,05180491 0,10525732 ! acid secretion GO:0046717 14 9 0,000 0,05180491 0,10516442 ! musculoskeletal movement GO:0050881 11 9 0,000 0,05180491 0,10507168 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,05180491 0,10497911 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,05180491 0,10488669 ! purine base metabolic process GO:0006144 18 9 0,000 0,05180491 0,10479445 ! oocyte differentiation GO:0009994 12 9 0,000 0,05180491 0,10470236 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,05180491 0,10461043 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,05180491 0,10451867 ! spleen development GO:0048536 15 9 0,000 0,05180491 0,10442707 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,05180491 0,10433563 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,05180491 0,10424434 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,05180491 0,10415322 ! detection of calcium ion GO:0005513 13 9 0,000 0,05180491 0,10406226 ! blastocyst formation GO:0001825 12 9 0,000 0,05180491 0,10397145 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,05180491 0,10388081 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,05180491 0,10379032 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,05180491 0,10369999 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,05180491 0,10360981 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05180491 0,1035198 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,05180491 0,10342993 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,05180491 0,10334023 ! prepulse inhibition GO:0060134 14 9 0,000 0,05180491 0,10325068 ! embryonic placenta development GO:0001892 12 9 0,000 0,05180491 0,10316129 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,05180491 0,10307205 ! insulin secretion GO:0030073 17 9 0,000 0,05180491 0,10298296 ! sequestering of metal ion GO:0051238 11 9 0,000 0,05180491 0,10289403 ! response to nicotine GO:0035094 16 9 0,000 0,05180491 0,10280525 ! establishment of cell polarity GO:0030010 12 9 0,000 0,05180491 0,10271662 ! regulation of synapse organization GO:0050807 12 9 0,000 0,05180491 0,10262815 ! localization within membrane GO:0051668 15 9 0,000 0,05180491 0,10253983 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,05322544 0,10526098 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,05322544 0,10517055 ! viral reproduction GO:0016032 92 63 1,000 0,05322544 0,10508028 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,05473662 0,10797103 ! B cell activation GO:0042113 104 65 1,000 0,05626288 0,11088657 ! activation of immune response GO:0002253 83 65 1,000 0,05626288 0,11079163 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05739434 0,11292299 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05739434 0,11282647 ! neuron fate specification GO:0048665 11 10 0,000 0,05739434 0,11273012 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05739434 0,11263393 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05739434 0,11253791 ! thyroid gland development GO:0030878 19 10 0,000 0,05739434 0,11244205 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05739434 0,11234636 ! synapsis GO:0007129 13 10 0,000 0,05739434 0,11225083 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05739434 0,11215546 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05739434 0,11206025 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05739434 0,1119652 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05739434 0,11187031 ! sulfate transport GO:0008272 12 10 0,000 0,05739434 0,11177559 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05739434 0,11168103 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,05739434 0,11158662 ! phospholipid efflux GO:0033700 16 10 0,000 0,05739434 0,11149237 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05739434 0,11139829 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05739434 0,11130436 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05739434 0,11121059 ! pathogenesis GO:0009405 13 10 0,000 0,05739434 0,11111698 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05739434 0,11102353 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05739434 0,11093023 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05739434 0,11083709 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,05739434 0,1107441 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05739434 0,11065128 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05739434 0,1105586 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05739434 0,11046609 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05739434 0,11037372 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05739434 0,11028151 ! B cell proliferation GO:0042100 14 10 0,000 0,05739434 0,11018946 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05739434 0,11009756 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05739434 0,11000581 ! forebrain cell migration GO:0021885 17 10 0,000 0,05739434 0,10991421 ! lipid digestion GO:0044241 15 10 0,000 0,05739434 0,10982277 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05739434 0,10973148 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05739434 0,10964034 ! UV protection GO:0009650 14 10 0,000 0,05739434 0,10954935 ! entry into host cell GO:0030260 20 10 0,000 0,05739434 0,10945852 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05739434 0,10936783 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05739434 0,10927729 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05739434 0,10918691 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05739434 0,10909667 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05739434 0,10900658 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05739434 0,10891664 ! regulation of organ growth GO:0046620 11 10 0,000 0,05739434 0,10882685 ! response to dsRNA GO:0043331 18 10 0,000 0,05739434 0,10873721 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05739434 0,10864771 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05739434 0,10855836 ! embryonic axis specification GO:0000578 12 10 0,000 0,05739434 0,10846916 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05739434 0,10838011 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05739434 0,1082912 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05739434 0,10820244 ! cranial nerve development GO:0021545 12 10 0,000 0,05739434 0,10811382 ! fucose catabolic process GO:0019317 16 10 0,000 0,05739434 0,10802535 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05739434 0,10793702 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05739434 0,10784883 ! protein sumoylation GO:0016925 12 10 0,000 0,05739434 0,10776079 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05739434 0,1076729 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05739434 0,10758514 ! zymogen activation GO:0031638 14 10 0,000 0,05739434 0,10749753 ! salivary gland development GO:0007431 22 10 0,000 0,05739434 0,10741007 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05739434 0,10732274 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05739434 0,10723556 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05739434 0,10714852 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05739434 0,10706162 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05739434 0,10697486 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05739434 0,10688824 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05739434 0,10680176 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05739434 0,10671542 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05739434 0,10662922 ! detection of bacterium GO:0016045 10 10 0,000 0,05739434 0,10654316 ! embryonic gut development GO:0048566 11 10 0,000 0,05739434 0,10645724 ! activation of innate immune response GO:0002218 10 10 0,000 0,05739434 0,10637145 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05739434 0,10628581 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05739434 0,1062003 ! developmental induction GO:0031128 13 10 0,000 0,05739434 0,10611493 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05739434 0,1060297 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,05739434 0,1059446 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05739434 0,10585964 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05739434 0,10577482 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,057804 0,10644452 ! axon guidance GO:0007411 99 66 1,000 0,057804 0,10635936 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,057804 0,10627434 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,05935975 0,10904747 ! acute inflammatory response GO:0002526 92 68 1,000 0,06092992 0,11184263 ! learning or memory GO:0007611 123 68 1,000 0,06092992 0,11175344 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,06092992 0,1116644 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,06251428 0,11447679 ! response to drug GO:0042493 108 69 1,000 0,06251428 0,11438571 ! rRNA transcription GO:0009303 17 11 0,000 0,06295113 0,11509349 ! respiratory burst GO:0045730 14 11 0,000 0,06295113 0,11500207 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,06295113 0,1149108 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,06295113 0,11481967 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,06295113 0,11472869 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,06295113 0,11463785 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,06295113 0,11454716 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,06295113 0,11445661 ! RNA polyadenylation GO:0043631 19 11 0,000 0,06295113 0,1143662 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,06295113 0,11427593 ! mating GO:0007618 14 11 0,000 0,06295113 0,11418581 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,06295113 0,11409583 ! T cell proliferation GO:0042098 20 11 0,000 0,06295113 0,11400599 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,06295113 0,11391629 ! bone resorption GO:0045453 16 11 0,000 0,06295113 0,11382674 ! regulated secretory pathway GO:0045055 14 11 0,000 0,06295113 0,11373732 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,06295113 0,11364804 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,06295113 0,11355891 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,06295113 0,11346991 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,06295113 0,11338106 ! syncytium formation GO:0006949 15 11 0,000 0,06295113 0,11329234 ! plasma membrane organization GO:0007009 18 11 0,000 0,06295113 0,11320376 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,06295113 0,11311532 ! mitotic spindle organization GO:0007052 15 11 0,000 0,06295113 0,11302702 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,06295113 0,11293885 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,06295113 0,11285082 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,06295113 0,11276293 ! adult heart development GO:0007512 11 11 0,000 0,06295113 0,11267518 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,06295113 0,11258756 ! temperature homeostasis GO:0001659 16 11 0,000 0,06295113 0,11250008 ! L-glutamate transport GO:0015813 16 11 0,000 0,06295113 0,11241274 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,06295113 0,11232553 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,06295113 0,11223846 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,06295113 0,11215152 ! stem cell development GO:0048864 29 11 0,000 0,06295113 0,11206471 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,06295113 0,11197804 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,06295113 0,11189151 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,06295113 0,1118051 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,06295113 0,11171883 ! vasoconstriction GO:0042310 15 11 0,000 0,06295113 0,1116327 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,06295113 0,11154669 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,06295113 0,11146082 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,06295113 0,11137508 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,06295113 0,11128948 ! ribosome assembly GO:0042255 13 11 0,000 0,06295113 0,111204 ! histone deacetylation GO:0016575 13 11 0,000 0,06295113 0,11111866 ! chromatin silencing GO:0006342 19 11 0,000 0,06295113 0,11103344 ! nucleosome positioning GO:0016584 13 11 0,000 0,06295113 0,11094836 ! T cell homeostasis GO:0043029 20 11 0,000 0,06295113 0,11086341 ! regulation of isotype switching GO:0045191 19 11 0,000 0,06295113 0,11077858 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,06295113 0,11069389 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,06295113 0,11060933 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,06295113 0,11052489 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,06295113 0,11044059 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,06295113 0,11035641 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,06295113 0,11027236 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,06295113 0,11018844 ! male genitalia development GO:0030539 13 11 0,000 0,06295113 0,11010465 ! cholesterol efflux GO:0033344 19 11 0,000 0,06295113 0,11002098 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,06295113 0,10993744 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,06295113 0,10985403 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,06295113 0,10977074 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,06295113 0,10968758 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,06295113 0,10960455 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,06295113 0,10952164 ! defense response to fungus GO:0050832 12 11 0,000 0,06295113 0,10943886 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,06295113 0,1093562 ! lysogeny GO:0030069 18 11 0,000 0,06295113 0,10927367 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,06295113 0,10919126 ! acrosome reaction GO:0007340 13 11 0,000 0,06295113 0,10910897 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,06295113 0,10902681 ! humoral immune response GO:0006959 86 70 1,000 0,06411261 0,11095486 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,06411261 0,11087144 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,06572471 0,11357387 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,06572471 0,11348861 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,06735034 0,11620839 GO:0045937|positive regulation of phosphate metabolic process, ! lactation GO:0007595 20 12 0,000 0,06847549 0,11806119 ! reproductive cellular process GO:0048610 14 12 0,000 0,06847549 0,11797276 ! tRNA modification GO:0006400 14 12 0,000 0,06847549 0,11788445 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06847549 0,11779628 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06847549 0,11770824 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06847549 0,11762033 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06847549 0,11753256 ! non-recombinational repair GO:0000726 19 12 0,000 0,06847549 0,11744491 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06847549 0,1173574 ! peroxisomal transport GO:0043574 21 12 0,000 0,06847549 0,11727001 ! cartilage condensation GO:0001502 18 12 0,000 0,06847549 0,11718276 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06847549 0,11709563 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06847549 0,11700864 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06847549 0,11692177 ! heart looping GO:0001947 15 12 0,000 0,06847549 0,11683504 ! palate development GO:0060021 15 12 0,000 0,06847549 0,11674843 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06847549 0,11666195 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06847549 0,11657559 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06847549 0,11648937 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06847549 0,11640327 ! arginine metabolic process GO:0006525 13 12 0,000 0,06847549 0,1163173 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06847549 0,11623146 ! methionine metabolic process GO:0006555 13 12 0,000 0,06847549 0,11614574 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06847549 0,11606015 ! Golgi organization GO:0007030 18 12 0,000 0,06847549 0,11597469 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06847549 0,11588935 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06847549 0,11580414 ! monoamine transport GO:0015844 13 12 0,000 0,06847549 0,11571905 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06847549 0,11563409 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06847549 0,11554925 ! L-amino acid transport GO:0015807 20 12 0,000 0,06847549 0,11546454 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06847549 0,11537995 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06847549 0,11529548 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06847549 0,11521114 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06847549 0,11512692 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06847549 0,11504283 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06847549 0,11495885 ! cerebellum development GO:0021549 13 12 0,000 0,06847549 0,114875 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06847549 0,11479127 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06847549 0,11470767 ! histone methylation GO:0016571 15 12 0,000 0,06847549 0,11462418 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06847549 0,11454082 ! gland morphogenesis GO:0022612 23 12 0,000 0,06847549 0,11445758 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06847549 0,11437446 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06847549 0,11429146 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06847549 0,11420858 ! intestinal absorption GO:0050892 19 12 0,000 0,06847549 0,11412582 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06847549 0,11404318 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06847549 0,11396066 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06847549 0,11387826 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06847549 0,11379597 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06847549 0,11371381 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06847549 0,11363177 ! response to cold GO:0009409 14 12 0,000 0,06847549 0,11354984 ! negative regulation of transport GO:0051051 116 73 1,000 0,06898931 0,11431947 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,0706414 0,11697281 ! regulation of ligase activity GO:0051340 114 75 1,000 0,07230641 0,1196437 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,07396759 0,12230443 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,07396759 0,12221657 ! cGMP metabolic process GO:0046068 16 13 0,000 0,07396759 0,12212883 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,07396759 0,12204122 ! water transport GO:0006833 17 13 0,000 0,07396759 0,12195374 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,07396759 0,12186638 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,07396759 0,12177914 ! lipid localization GO:0010876 24 13 0,000 0,07396759 0,12169203 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,07396759 0,12160505 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,07396759 0,12151819 ! organelle fusion GO:0048284 28 13 0,000 0,07396759 0,12143145 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,07396759 0,12134484 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,07396759 0,12125835 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,07396759 0,12117198 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,07396759 0,12108574 ! response to hexose stimulus GO:0009746 19 13 0,000 0,07396759 0,12099962 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,07396759 0,12091362 ! glutamate metabolic process GO:0006536 18 13 0,000 0,07396759 0,12082774 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,07396759 0,12074199 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,07396759 0,12065636 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,07396759 0,12057085 ! NAD metabolic process GO:0019674 21 13 0,000 0,07396759 0,12048546 ! exocrine system development GO:0035272 27 13 0,000 0,07396759 0,12040019 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,07396759 0,12031504 ! bone mineralization GO:0030282 15 13 0,000 0,07396759 0,12023001 ! regulation of exocytosis GO:0017157 17 13 0,000 0,07396759 0,1201451 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,07396759 0,12006031 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,07396759 0,11997564 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,07396759 0,11989109 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,07396759 0,11980666 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,07396759 0,11972235 ! genitalia development GO:0048806 15 13 0,000 0,07396759 0,11963816 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,07396759 0,11955409 ! cellular pigmentation GO:0033059 24 13 0,000 0,07396759 0,11947013 ! tissue regeneration GO:0042246 21 13 0,000 0,07396759 0,11938629 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,07396759 0,11930257 ! cofactor transport GO:0051181 19 13 0,000 0,07396759 0,11921897 ! NADP metabolic process GO:0006739 18 13 0,000 0,07396759 0,11913548 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,07396759 0,11905211 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,07396759 0,11896886 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07396759 0,11888572 ! gas transport GO:0015669 18 13 0,000 0,07396759 0,1188027 ! heme biosynthetic process GO:0006783 20 13 0,000 0,07396759 0,11871979 ! regulation of axon extension GO:0030516 23 13 0,000 0,07396759 0,118637 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,07396759 0,11855433 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,07396759 0,11847177 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,07396759 0,11838933 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,07396759 0,118307 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,07396759 0,11822478 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,07396759 0,11814268 ! tRNA metabolic process GO:0006399 95 76 1,000 0,07398413 0,11808709 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,07398413 0,1180052 ! gland development GO:0048732 148 77 1,000 0,07567435 0,12061746 ! protein ubiquitination GO:0016567 125 77 1,000 0,07567435 0,12053393 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,07737687 0,12316042 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,07942763 0,12633717 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,07942763 0,12624986 ! superoxide anion generation GO:0042554 18 14 0,000 0,07942763 0,12616267 ! neuron maturation GO:0042551 21 14 0,000 0,07942763 0,1260756 ! regulation of S phase GO:0033261 18 14 0,000 0,07942763 0,12598865 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07942763 0,12590182 ! myotube differentiation GO:0014902 21 14 0,000 0,07942763 0,12581511 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07942763 0,12572852 ! inositol metabolic process GO:0006020 20 14 0,000 0,07942763 0,12564205 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07942763 0,1255557 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07942763 0,12546947 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07942763 0,12538335 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07942763 0,12529735 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07942763 0,12521147 ! response to cAMP GO:0051591 19 14 0,000 0,07942763 0,12512571 ! startle response GO:0001964 21 14 0,000 0,07942763 0,12504007 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07942763 0,12495454 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07942763 0,12486913 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,07942763 0,12478384 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07942763 0,12469866 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07942763 0,1246136 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,07942763 0,12452866 ! glycine metabolic process GO:0006544 22 14 0,000 0,07942763 0,12444383 ! pituitary gland development GO:0021983 23 14 0,000 0,07942763 0,12435912 ! lysosomal transport GO:0007041 20 14 0,000 0,07942763 0,12427452 ! regulation of heart rate GO:0002027 23 14 0,000 0,07942763 0,12419004 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07942763 0,12410567 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07942763 0,12402141 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07942763 0,12393727 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07942763 0,12385325 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07942763 0,12376934 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07942763 0,12368554 ! axon cargo transport GO:0008088 27 14 0,000 0,07942763 0,12360186 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07942763 0,12351828 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07942763 0,12343483 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07942763 0,12335148 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,07942763 0,12326825 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07942763 0,12318513 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07942763 0,12310212 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07942763 0,12301922 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07942763 0,12293643 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,07942763 0,12285376 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07942763 0,1227712 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07942763 0,12268875 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,07942763 0,1226064 ! muscle maintenance GO:0046716 19 14 0,000 0,07942763 0,12252417 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07942763 0,12244205 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07942763 0,12236004 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07942763 0,12227814 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07942763 0,12219635 ! cell killing GO:0001906 20 14 0,000 0,07942763 0,12211467 ! cilium assembly GO:0042384 20 14 0,000 0,07942763 0,12203309 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07942763 0,12195163 ! forebrain development GO:0030900 131 80 1,000 0,08081803 0,12400364 ! mRNA transport GO:0051028 121 81 1,000 0,08255626 0,12658627 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,08255626 0,12650193 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,08485578 0,12993894 ! positive regulation of cell size GO:0045793 20 15 0,000 0,08485578 0,12985249 ! metencephalon development GO:0022037 19 15 0,000 0,08485578 0,12976615 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,08485578 0,12967993 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,08485578 0,12959382 ! skin development GO:0043588 25 15 0,000 0,08485578 0,12950782 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,08485578 0,12942194 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,08485578 0,12933618 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,08485578 0,12925052 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,08485578 0,12916498 ! bile acid metabolic process GO:0008206 22 15 0,000 0,08485578 0,12907956 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,08485578 0,12899424 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,08485578 0,12890904 ! adult walking behavior GO:0007628 25 15 0,000 0,08485578 0,12882395 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,08485578 0,12873898 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,08485578 0,12865411 ! myoblast differentiation GO:0045445 27 15 0,000 0,08485578 0,12856936 ! centrosome cycle GO:0007098 16 15 0,000 0,08485578 0,12848472 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,08485578 0,12840019 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,08485578 0,12831577 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,08485578 0,12823147 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,08485578 0,12814727 ! cerebral cortex development GO:0021987 29 15 0,000 0,08485578 0,12806318 ! response to osmotic stress GO:0006970 22 15 0,000 0,08485578 0,12797921 ! vesicle coating GO:0006901 25 15 0,000 0,08485578 0,12789534 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,08485578 0,12781159 ! DNA integration GO:0015074 22 15 0,000 0,08485578 0,12772794 ! peptide secretion GO:0002790 27 15 0,000 0,08485578 0,1276444 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,08485578 0,12756097 ! regulation of vasodilation GO:0042312 24 15 0,000 0,08485578 0,12747766 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,08485578 0,12739445 ! neuron recognition GO:0008038 22 15 0,000 0,08485578 0,12731134 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,08485578 0,12722835 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,08485578 0,12714547 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,08485578 0,12706269 ! biomineral formation GO:0031214 18 15 0,000 0,08485578 0,12698002 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,08485578 0,12689746 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,08485578 0,126815 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,08485578 0,12673266 ! dopamine metabolic process GO:0042417 30 15 0,000 0,08485578 0,12665042 ! organic cation transport GO:0015695 19 15 0,000 0,08485578 0,12656828 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,08485578 0,12648625 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,08485578 0,12640433 ! defense response to virus GO:0051607 27 15 0,000 0,08485578 0,12632252 ! peptide hormone processing GO:0016486 19 15 0,000 0,08485578 0,12624081 ! Golgi vesicle transport GO:0048193 138 85 1,000 0,08962242 0,133246 ! rRNA metabolic process GO:0016072 107 85 1,000 0,08962242 0,13315992 GO:0006364|rRNA processing, ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,08962242 0,13307395 ! regulation of membrane potential GO:0042391 128 85 1,000 0,08962242 0,1329881 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,08962242 0,13290236 ! protein secretion GO:0009306 27 16 0,000 0,09025223 0,13375009 ! hormone secretion GO:0046879 25 16 0,000 0,09025223 0,13366396 ! bone remodeling GO:0046849 24 16 0,000 0,09025223 0,13357795 ! endothelial cell migration GO:0043542 22 16 0,000 0,09025223 0,13349205 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,09025223 0,13340626 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09025223 0,13332057 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,09025223 0,133235 ! glial cell development GO:0021782 24 16 0,000 0,09025223 0,13314954 ! patterning of blood vessels GO:0001569 24 16 0,000 0,09025223 0,13306419 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,09025223 0,13297895 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,09025223 0,13289381 ! protein polyubiquitination GO:0000209 26 16 0,000 0,09025223 0,13280879 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,09025223 0,13272387 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,09025223 0,13263906 ! fructose metabolic process GO:0006000 20 16 0,000 0,09025223 0,13255436 ! regulation of protein binding GO:0043393 27 16 0,000 0,09025223 0,13246977 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,09025223 0,13238529 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,09025223 0,13230091 ! protein export from nucleus GO:0006611 24 16 0,000 0,09025223 0,13221665 ! negative regulation of immune response GO:0050777 28 16 0,000 0,09025223 0,13213249 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,09025223 0,13204843 ! DNA replication initiation GO:0006270 25 16 0,000 0,09025223 0,13196448 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,09025223 0,13188064 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,09025223 0,13179691 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,09025223 0,13171328 ! diencephalon development GO:0021536 25 16 0,000 0,09025223 0,13162976 ! oogenesis GO:0048477 23 16 0,000 0,09025223 0,13154635 ! neural crest cell migration GO:0001755 24 16 0,000 0,09025223 0,13146304 ! G1 phase GO:0051318 27 16 0,000 0,09025223 0,13137983 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,09025223 0,13129673 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,09025223 0,13121374 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,09025223 0,13113085 ! steroid catabolic process GO:0006706 22 16 0,000 0,09025223 0,13104806 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,09025223 0,13096538 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,09025223 0,13088281 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,09025223 0,13080034 ! sperm-egg recognition GO:0035036 16 16 0,000 0,09025223 0,13071797 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,09025223 0,1306357 ! nerve development GO:0021675 18 16 0,000 0,09025223 0,13055354 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,09025223 0,13047149 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,09025223 0,13038953 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,0950356 0,13721399 ! establishment of RNA localization GO:0051236 128 88 1,000 0,0950356 0,13712791 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,0950356 0,13704193 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,09561717 0,13779417 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,09561717 0,13770789 ! negative regulation of defense response GO:0031348 19 17 0,000 0,09561717 0,13762171 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,09561717 0,13753564 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,09561717 0,13744968 ! glycerol metabolic process GO:0006071 20 17 0,000 0,09561717 0,13736383 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,09561717 0,13727809 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,09561717 0,13719245 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,09561717 0,13710692 ! signal complex assembly GO:0007172 29 17 0,000 0,09561717 0,13702149 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,09561717 0,13693617 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,09561717 0,13685096 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,09561717 0,13676585 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,09561717 0,13668085 ! memory GO:0007613 25 17 0,000 0,09561717 0,13659596 ! keratinization GO:0031424 17 17 0,000 0,09561717 0,13651117 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,09561717 0,13642648 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,09561717 0,13634191 ! retinoid metabolic process GO:0001523 22 17 0,000 0,09561717 0,13625743 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,09561717 0,13617306 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,09561717 0,1360888 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,09561717 0,13600463 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,09561717 0,13592058 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,09561717 0,13583662 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,09561717 0,13575277 ! membrane budding GO:0006900 29 17 0,000 0,09561717 0,13566903 ! heme metabolic process GO:0042168 27 17 0,000 0,09561717 0,13558538 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,09561717 0,13550184 ! body fluid secretion GO:0007589 27 17 0,000 0,09561717 0,13541841 ! stem cell differentiation GO:0048863 36 17 0,000 0,09561717 0,13533507 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,09561717 0,13525184 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,09561717 0,13516871 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,09561717 0,13508568 ! sensory perception of pain GO:0019233 23 17 0,000 0,09561717 0,13500276 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,09561717 0,13491993 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,09561717 0,13483721 ! synaptogenesis GO:0007416 24 17 0,000 0,09561717 0,13475459 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,09561717 0,13467207 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,09561717 0,13458965 ! cell-cell junction organization GO:0045216 25 17 0,000 0,09561717 0,13450734 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,09561717 0,13442512 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,09561717 0,134343 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,09561717 0,13426098 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,09561717 0,13417907 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,09561717 0,13409725 ! reproductive developmental process GO:0003006 127 89 1,000 0,09686064 0,13575837 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,0986957 0,13824611 ! RNA localization GO:0006403 135 91 1,000 0,10054061 0,14074461 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,10095078 0,14123284 ! positive regulation of translation GO:0045727 28 18 0,000 0,10095078 0,14114698 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,10095078 0,14106123 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,10095078 0,14097558 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,10095078 0,14089004 ! cAMP metabolic process GO:0046058 33 18 0,000 0,10095078 0,1408046 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,10095078 0,14071927 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,10095078 0,14063403 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,10095078 0,1405489 ! axis specification GO:0009798 26 18 0,000 0,10095078 0,14046388 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,10095078 0,14037895 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,10095078 0,14029413 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,10095078 0,14020941 ! glutamine metabolic process GO:0006541 23 18 0,000 0,10095078 0,1401248 ! response to retinoic acid GO:0032526 25 18 0,000 0,10095078 0,14004028 ! central nervous system neuron development GO:0021954 30 18 0,000 0,10095078 0,13995587 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,10095078 0,13987156 ! fucose metabolic process GO:0006004 26 18 0,000 0,10095078 0,13978735 ! response to fungus GO:0009620 19 18 0,000 0,10095078 0,13970324 ! peptide cross-linking GO:0018149 31 18 0,000 0,10095078 0,13961923 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,10095078 0,13953533 ! heart process GO:0003015 27 18 0,000 0,10095078 0,13945152 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,10095078 0,13936782 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,10095078 0,13928422 ! visual learning GO:0008542 35 18 0,000 0,10095078 0,13920071 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,10095078 0,13911731 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,10095078 0,139034 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,10095078 0,1389508 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,10095078 0,1388677 ! vitamin transport GO:0051180 24 18 0,000 0,10095078 0,13878469 ! hormone transport GO:0009914 27 18 0,000 0,10095078 0,13870178 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,10095078 0,13861898 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,10095078 0,13853627 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,10095078 0,13845366 ! cell-cell recognition GO:0009988 20 18 0,000 0,10095078 0,13837115 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,10095078 0,13828874 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,10095078 0,13820642 ! regulation of glucose import GO:0046324 21 18 0,000 0,10095078 0,1381242 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,10095078 0,13804209 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,10239518 0,13993399 ! cell fate commitment GO:0045165 141 92 1,000 0,10239518 0,1398509 ! positive regulation of immune response GO:0050778 121 92 1,000 0,10239518 0,1397679 ! sulfur metabolic process GO:0006790 118 92 1,000 0,10239518 0,139685 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,10425924 0,1421436 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,10425924 0,14205939 ! response to oxidative stress GO:0006979 141 94 1,000 0,10613261 0,14452635 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,10625323 0,14460499 ! positive regulation of ossification GO:0045778 30 19 0,000 0,10625323 0,14451948 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,10625323 0,14443406 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,10625323 0,14434875 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,10625323 0,14426354 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,10625323 0,14417843 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,10625323 0,14409342 ! regeneration GO:0031099 32 19 0,000 0,10625323 0,14400851 ! response to alkaloid GO:0043279 32 19 0,000 0,10625323 0,14392369 ! sensory perception of taste GO:0050909 23 19 0,000 0,10625323 0,14383898 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,10625323 0,14375437 ! smooth muscle contraction GO:0006939 36 19 0,000 0,10625323 0,14366986 ! peroxisome organization GO:0007031 29 19 0,000 0,10625323 0,14358545 ! digestive system process GO:0022600 30 19 0,000 0,10625323 0,14350114 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,10625323 0,14341692 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,10625323 0,14333281 ! response to vitamin A GO:0033189 26 19 0,000 0,10625323 0,14324879 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,10625323 0,14316487 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,10625323 0,14308105 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,10625323 0,14299733 ! plasma membrane fusion GO:0045026 23 19 0,000 0,10625323 0,1429137 ! cytolysis GO:0019835 20 19 0,000 0,10625323 0,14283018 ! renal system process GO:0003014 35 19 0,000 0,10625323 0,14274675 ! vasodilation GO:0042311 33 19 0,000 0,10625323 0,14266342 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,10625323 0,14258018 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,10625323 0,14249705 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,10625323 0,14241401 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,10625323 0,14233106 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,10625323 0,14224821 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,10625323 0,14216546 ! sarcomere organization GO:0045214 23 19 0,000 0,10625323 0,14208281 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,10625323 0,14200025 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,10625323 0,14191779 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,10625323 0,14183542 ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,10625323 0,14175315 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,10625323 0,14167098 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,10625323 0,1415889 ! protein stabilization GO:0050821 26 19 0,000 0,10625323 0,14150691 ! angiogenesis GO:0001525 149 95 1,000 0,10801514 0,14377015 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,10990663 0,14620315 ! in utero embryonic development GO:0001701 147 96 1,000 0,10990663 0,14611864 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,10990663 0,14603423 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,10990663 0,14594992 ! protein maturation GO:0051604 129 96 1,000 0,10990663 0,1458657 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,11152472 0,14792782 ! iron ion transport GO:0006826 37 20 0,000 0,11152472 0,14784256 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,11152472 0,1477574 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,11152472 0,14767233 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,11152472 0,14758737 ! response to vitamin GO:0033273 29 20 0,000 0,11152472 0,1475025 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,11152472 0,14741773 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,11152472 0,14733305 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,11152472 0,14724848 ! spinal cord development GO:0021510 31 20 0,000 0,11152472 0,147164 ! response to ethanol GO:0045471 37 20 0,000 0,11152472 0,14707961 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,11152472 0,14699533 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,11152472 0,14691114 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,11152472 0,14682704 ! chromosome condensation GO:0030261 31 20 0,000 0,11152472 0,14674305 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,11152472 0,14665915 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,11152472 0,14657534 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,11152472 0,14649163 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,11152472 0,14640802 ! DNA modification GO:0006304 28 20 0,000 0,11152472 0,1463245 ! collagen fibril organization GO:0030199 45 20 0,000 0,11152472 0,14624107 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,11152472 0,14615775 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,11152472 0,14607451 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,11152472 0,14599137 ! collagen catabolic process GO:0030574 25 20 0,000 0,11152472 0,14590833 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,11152472 0,14582538 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,11152472 0,14574253 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,11152472 0,14565976 ! alditol metabolic process GO:0019400 24 20 0,000 0,11152472 0,1455771 ! actin filament-based movement GO:0030048 34 20 0,000 0,11152472 0,14549452 ! extracellular structure organization GO:0043062 156 99 1,000 0,1156333 0,15076904 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,11676541 0,15215889 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,11676541 0,15207273 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,11676541 0,15198666 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,11676541 0,1519007 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,11676541 0,15181483 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,11676541 0,15172906 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,11676541 0,15164339 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,11676541 0,15155781 ! vesicle docking GO:0048278 27 21 0,000 0,11676541 0,15147233 ! phototransduction GO:0007602 25 21 0,000 0,11676541 0,15138694 ! visual behavior GO:0007632 39 21 0,000 0,11676541 0,15130165 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,11676541 0,15121646 ! ovarian follicle development GO:0001541 30 21 0,000 0,11676541 0,15113137 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,11676541 0,15104636 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,11676541 0,15096146 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,11676541 0,15087665 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,11676541 0,15079193 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,11676541 0,15070732 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,11676541 0,15062279 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,11676541 0,15053836 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,11676541 0,15045403 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,11676541 0,15036978 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,11676541 0,15028564 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,11676541 0,15020159 ! fatty acid transport GO:0015908 30 21 0,000 0,11676541 0,15011763 ! immunoglobulin production GO:0002377 33 21 0,000 0,11676541 0,15003376 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,11676541 0,14994999 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,11676541 0,14986631 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,11676541 0,14978273 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,11676541 0,14969924 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,11676541 0,14961584 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,11676541 0,14953254 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,11676541 0,14944932 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,11676541 0,1493662 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,11676541 0,14928318 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,11676541 0,14920024 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,11676541 0,1491174 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,11676541 0,14903465 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,11676541 0,14895199 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,11676541 0,14886942 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,11755902 0,1497982 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,12197548 0,15533976 ! viral genome replication GO:0019079 29 22 0,000 0,12197548 0,1552538 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,12197548 0,15516793 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,12197548 0,15508215 ! leukocyte adhesion GO:0007159 38 22 0,000 0,12197548 0,15499647 ! molting cycle process GO:0022404 40 22 0,000 0,12197548 0,15491089 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,12197548 0,15482539 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,12197548 0,15474 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,12197548 0,15465469 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,12197548 0,15456948 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,12197548 0,15448437 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,12197548 0,15439935 ! lysosome organization GO:0007040 37 22 0,000 0,12197548 0,15431442 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,12197548 0,15422958 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,12197548 0,15414484 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,12197548 0,15406019 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,12197548 0,15397564 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,12197548 0,15389118 ! membrane depolarization GO:0051899 35 22 0,000 0,12197548 0,15380681 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,12197548 0,15372253 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,12197548 0,15363834 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,12197548 0,15355425 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,12197548 0,15347025 ! blastocyst development GO:0001824 37 22 0,000 0,12197548 0,15338634 ! neural tube closure GO:0001843 33 22 0,000 0,12197548 0,15330252 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,12197548 0,1532188 ! neuron fate commitment GO:0048663 32 23 0,000 0,12715512 0,15963798 ! embryonic pattern specification GO:0009880 31 23 0,000 0,12715512 0,15955089 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,12715512 0,1594639 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,12715512 0,159377 ! vesicle targeting GO:0006903 32 23 0,000 0,12715512 0,15929019 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,12715512 0,15920348 ! osteoblast differentiation GO:0001649 40 23 0,000 0,12715512 0,15911686 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,12715512 0,15903034 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,12715512 0,15894391 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,12715512 0,15885757 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,12715512 0,15877133 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,12715512 0,15868518 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,12715512 0,15859913 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,12715512 0,15851316 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,12715512 0,1584273 ! cell fate determination GO:0001709 45 23 0,000 0,12715512 0,15834152 ! pentose metabolic process GO:0019321 31 23 0,000 0,12715512 0,15825584 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,12715512 0,15817025 ! spermatid development GO:0007286 33 23 0,000 0,12715512 0,15808475 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,12715512 0,15799934 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,12715512 0,15791403 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,12715512 0,15782881 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,12715512 0,15774368 ! telomere organization GO:0032200 32 23 0,000 0,12715512 0,15765865 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,12715512 0,1575737 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,12715512 0,15748885 ! regulation of amine transport GO:0051952 38 23 0,000 0,12715512 0,15740408 ! liver development GO:0001889 40 23 0,000 0,12715512 0,15731941 ! initiation of viral infection GO:0019059 42 24 0,000 0,1323045 0,16360234 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,1323045 0,16351443 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,1323045 0,16342662 ! superoxide metabolic process GO:0006801 32 24 0,000 0,1323045 0,16333889 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,1323045 0,16325127 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,1323045 0,16316373 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,1323045 0,16307629 ! sperm motility GO:0030317 27 24 0,000 0,1323045 0,16298895 ! vacuole organization GO:0007033 39 24 0,000 0,1323045 0,16290169 ! receptor metabolic process GO:0043112 37 24 0,000 0,1323045 0,16281453 ! neural crest cell development GO:0014032 39 24 0,000 0,1323045 0,16272747 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,1323045 0,16264049 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,1323045 0,16255361 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,1323045 0,16246682 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,1323045 0,16238013 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,1323045 0,16229353 ! glutathione metabolic process GO:0006749 29 24 0,000 0,1323045 0,16220702 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,1323045 0,1621206 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,1323045 0,16203427 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,1323045 0,16194804 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,1374238 0,16812486 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,1374238 0,16803548 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,1374238 0,16794619 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,1374238 0,167857 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,1374238 0,16776791 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,1374238 0,16767891 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,1374238 0,16759 ! peptide transport GO:0015833 43 25 0,000 0,1374238 0,16750119 ! male gonad development GO:0008584 33 25 0,000 0,1374238 0,16741247 ! iron ion homeostasis GO:0055072 39 25 0,000 0,1374238 0,16732384 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,1374238 0,16723531 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,1374238 0,16714687 ! phospholipid transport GO:0015914 35 25 0,000 0,1374238 0,16705853 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,1374238 0,16697028 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,1374238 0,16688212 ! detection of light stimulus GO:0009583 30 25 0,000 0,1374238 0,16679406 ! leukocyte proliferation GO:0070661 39 25 0,000 0,1374238 0,16670609 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,14251318 0,17278878 ! translational initiation GO:0006413 43 26 0,000 0,14251318 0,17269774 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,14251318 0,1726068 ! circadian rhythm GO:0007623 42 26 0,000 0,14251318 0,17251596 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,14251318 0,17242521 ! post-embryonic development GO:0009791 42 26 0,000 0,14251318 0,17233455 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,14251318 0,17224399 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,14251318 0,17215353 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,14251318 0,17206316 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,14251318 0,17197288 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,14251318 0,1718827 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,14251318 0,17179262 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,14251318 0,17170263 ! regulation of coagulation GO:0050818 39 26 0,000 0,14251318 0,17161273 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,14757283 0,17761251 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,14757283 0,17751961 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,14757283 0,17742682 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,14757283 0,17733412 ! membrane docking GO:0022406 39 27 0,000 0,14757283 0,17724151 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,14757283 0,17714901 ! catechol metabolic process GO:0009712 43 27 0,000 0,14757283 0,1770566 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,14757283 0,17696428 ! acute-phase response GO:0006953 42 27 0,000 0,14757283 0,17687207 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,14757283 0,17677995 ! myofibril assembly GO:0030239 36 27 0,000 0,14757283 0,17668792 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,14757283 0,17659599 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,14757283 0,17650416 ! natural killer cell activation GO:0030101 35 27 0,000 0,14757283 0,17641242 ! lipid oxidation GO:0034440 38 27 0,000 0,14757283 0,17632078 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,14757283 0,17622923 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,14757283 0,17613778 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,14757283 0,17604642 ! gene silencing GO:0016458 41 27 0,000 0,14757283 0,17595516 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,1526029 0,18185838 ! phenol metabolic process GO:0018958 44 28 0,000 0,1526029 0,1817642 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,1526029 0,18167012 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,1526029 0,18157614 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,1526029 0,18148225 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,1526029 0,18138846 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,1526029 0,18129477 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,1526029 0,18120117 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,1526029 0,18110768 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,1526029 0,18101427 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,1526029 0,18092097 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,1526029 0,18082776 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,1526029 0,18073464 ! mesoderm formation GO:0001707 46 28 0,000 0,1526029 0,18064162 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,1526029 0,1805487 ! BMP signaling pathway GO:0030509 40 28 0,000 0,1526029 0,18045587 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,1526029 0,18036314 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,1526029 0,18027051 ! neural tube formation GO:0001841 41 28 0,000 0,1526029 0,18017796 ! placenta development GO:0001890 37 28 0,000 0,1526029 0,18008552 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,15760358 0,18589141 ! regulation of innate immune response GO:0045088 38 29 0,000 0,15760358 0,18579613 ! ovulation cycle process GO:0022602 41 29 0,000 0,15760358 0,18570094 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,15760358 0,18560586 ! protein targeting to membrane GO:0006612 53 29 0,000 0,15760358 0,18551087 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,15760358 0,18541598 ! mismatch repair GO:0006298 34 29 0,000 0,15760358 0,18532119 ! muscle cell development GO:0055001 38 29 0,000 0,15760358 0,18522649 ! formation of primary germ layer GO:0001704 48 29 0,000 0,15760358 0,18513189 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,15760358 0,18503739 ! eye morphogenesis GO:0048592 51 29 0,000 0,15760358 0,18494298 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,15760358 0,18484867 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,16257504 0,19058236 ! collagen metabolic process GO:0032963 40 30 0,000 0,16257504 0,19048527 ! organic anion transport GO:0015711 51 30 0,000 0,16257504 0,19038829 ! cholesterol transport GO:0030301 46 30 0,000 0,16257504 0,1902914 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,16257504 0,19019461 ! spliceosome assembly GO:0000245 49 30 0,000 0,16257504 0,19009791 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,16257504 0,19000132 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,16257504 0,18990482 ! ceramide metabolic process GO:0006672 43 30 0,000 0,16257504 0,18980842 ! ovulation cycle GO:0042698 43 30 0,000 0,16257504 0,18971212 ! hindbrain development GO:0030902 45 30 0,000 0,16257504 0,18961592 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,16257504 0,18951981 ! adult locomotory behavior GO:0008344 47 30 0,000 0,16257504 0,18942381 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,16257504 0,1893279 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,16257504 0,18923208 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,16257504 0,18913637 ! negative regulation of secretion GO:0051048 49 31 0,000 0,16751744 0,19478772 ! glial cell differentiation GO:0010001 55 31 0,000 0,16751744 0,19468929 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,16751744 0,19459097 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,16751744 0,19449274 ! odontogenesis GO:0042476 50 31 0,000 0,16751744 0,19439461 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,16751744 0,19429658 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,16751744 0,19419865 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,16751744 0,19410081 ! metanephros development GO:0001656 58 31 0,000 0,16751744 0,19400308 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,16751744 0,19390544 ! cell fate specification GO:0001708 37 31 0,000 0,16751744 0,1938079 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,16751744 0,19371046 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,16751744 0,19361312 ! RNA modification GO:0009451 40 31 0,000 0,16751744 0,19351588 ! regulation of muscle development GO:0048634 48 32 0,000 0,17243095 0,19909196 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,17243095 0,19899207 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,17243095 0,19889227 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,17243095 0,19879258 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 0,000 0,17243095 0,19869298 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,17243095 0,19859349 ! cytokine production GO:0001816 44 32 0,000 0,17243095 0,19849409 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,17243095 0,19839479 ! vesicle localization GO:0051648 47 32 0,000 0,17243095 0,1982956 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,17731574 0,2038112 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,17731574 0,2037094 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,17731574 0,2036077 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,17731574 0,20350609 ! ear morphogenesis GO:0042471 42 33 0,000 0,17731574 0,2034046 ! actomyosin structure organization GO:0031032 43 33 0,000 0,17731574 0,2033032 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,17731574 0,2032019 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,17731574 0,2031007 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,17731574 0,20299961 ! female gonad development GO:0008585 49 33 0,000 0,17731574 0,20289861 ! positive regulation of cell development GO:0010720 54 33 0,000 0,17731574 0,20279772 ! lipid homeostasis GO:0055088 55 33 0,000 0,17731574 0,20269693 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,17731574 0,20259623 ! regulation of proteolysis GO:0030162 50 33 0,000 0,17731574 0,20249564 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,17731574 0,20239514 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,17731574 0,20229475 ! mRNA catabolic process GO:0006402 48 34 0,000 0,18217198 0,20773206 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,18217198 0,20762912 ! feeding behavior GO:0007631 45 34 0,000 0,18217198 0,20752628 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,18217198 0,20742354 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,18217198 0,20732091 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,18217198 0,20721838 ! neuron migration GO:0001764 46 34 0,000 0,18217198 0,20711595 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,18217198 0,20701362 ! female gamete generation GO:0007292 43 34 0,000 0,18217198 0,20691139 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,18217198 0,20680926 ! polyol metabolic process GO:0019751 44 34 0,000 0,18217198 0,20670723 ! aerobic respiration GO:0009060 47 34 0,000 0,18217198 0,2066053 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,18217198 0,20650348 ! embryonic organ development GO:0048568 45 34 0,000 0,18217198 0,20640175 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,18217198 0,20630013 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,18699983 0,21166319 ! Notch signaling pathway GO:0007219 56 35 0,000 0,18699983 0,21155908 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,18699983 0,21145507 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,18699983 0,21135116 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,18699983 0,21124735 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,18699983 0,21114365 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,18699983 0,21104004 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,18699983 0,21093654 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,18699983 0,21083314 ! pigment metabolic process GO:0042440 61 35 0,000 0,18699983 0,21072984 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,19179945 0,21603268 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,19179945 0,21592694 ! organic ether metabolic process GO:0018904 46 36 0,000 0,19179945 0,2158213 ! neural tube development GO:0021915 50 36 0,000 0,19179945 0,21571577 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,19179945 0,21561033 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,19179945 0,215505 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,19179945 0,21539978 ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,19657101 0,22065072 ! learning GO:0007612 67 37 0,000 0,19657101 0,22054309 ! ion transmembrane transport GO:0034220 56 37 0,000 0,19657101 0,22043556 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,19657101 0,22032813 ! regulation of protein secretion GO:0050708 51 37 0,000 0,19657101 0,22022081 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,19657101 0,2201136 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,20131468 0,2253157 ! gliogenesis GO:0042063 71 38 0,000 0,20131468 0,22520611 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,20131468 0,22509662 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,20131468 0,22498725 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,20131468 0,22487798 ! phagocytosis GO:0006909 60 38 0,000 0,20131468 0,22476881 ! maintenance of location in cell GO:0051651 69 38 0,000 0,20131468 0,22465975 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,2060306 0,22981105 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,2060306 0,22969965 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,2060306 0,22958836 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,2060306 0,22947718 ! male sex differentiation GO:0046661 53 39 0,000 0,2060306 0,22936611 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,2060306 0,22925514 ! chromatin remodeling GO:0006338 68 39 0,000 0,2060306 0,22914428 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,2060306 0,22903353 ! JNK cascade GO:0007254 54 39 0,000 0,2060306 0,22892289 ! developmental growth GO:0048589 62 39 0,000 0,2060306 0,22881235 ! cell growth GO:0016049 61 39 0,000 0,2060306 0,22870192 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,21071895 0,23379333 ! response to calcium ion GO:0051592 58 40 0,000 0,21071895 0,23368061 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,21071895 0,23356799 ! regulation of tube size GO:0035150 60 40 0,000 0,21071895 0,23345548 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,21071895 0,23334308 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,21071895 0,23323079 ! peptide metabolic process GO:0006518 56 40 0,000 0,21071895 0,23311861 ! inner ear development GO:0048839 57 40 0,000 0,21071895 0,23300653 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,21071895 0,23289456 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,21071895 0,2327827 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,21071895 0,23267095 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,21537988 0,23770332 ! endosome transport GO:0016197 71 41 0,000 0,21537988 0,23758931 ! striated muscle contraction GO:0006941 62 41 0,000 0,21537988 0,23747542 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,21537988 0,23736163 ! biopolymer methylation GO:0043414 62 41 0,000 0,21537988 0,23724795 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,21537988 0,23713438 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,22001355 0,24212017 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,22001355 0,24200438 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,22001355 0,2418887 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,22001355 0,24177313 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,22001355 0,24165767 ! excretion GO:0007588 63 42 0,000 0,22001355 0,24154232 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,22001355 0,24142708 ! leukocyte migration GO:0050900 60 43 0,000 0,22462012 0,24636446 ! neuromuscular process GO:0050905 79 43 0,000 0,22462012 0,24624704 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,22462012 0,24612972 ! tRNA processing GO:0008033 49 43 0,000 0,22462012 0,24601251 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,22462012 0,24589542 ! vesicle organization GO:0016050 79 43 0,000 0,22462012 0,24577844 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,22462012 0,24566157 ! methylation GO:0032259 64 43 0,000 0,22462012 0,24554481 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,22919975 0,25043203 ! glycolysis GO:0006096 53 44 0,000 0,22919975 0,25031312 ! regulation of ion transport GO:0043269 57 44 0,000 0,22919975 0,25019432 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,22919975 0,25007563 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,22919975 0,24995705 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,22919975 0,24983859 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,22919975 0,24972024 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,22919975 0,249602 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,22919975 0,24948387 ! RNA catabolic process GO:0006401 64 45 0,000 0,23375259 0,25431928 ! positive regulation of defense response GO:0031349 59 45 0,000 0,23375259 0,25419903 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,23375259 0,2540789 ! cell recognition GO:0008037 58 45 0,000 0,23375259 0,25395888 ! cell maturation GO:0048469 60 45 0,000 0,23375259 0,25383898 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,2382788 0,25863201 ! cell redox homeostasis GO:0045454 63 46 0,000 0,2382788 0,25851002 ! regulation of ossification GO:0030278 71 46 0,000 0,2382788 0,25838813 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,2382788 0,25826637 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,24277853 0,2630196 ! viral infectious cycle GO:0019058 71 47 0,000 0,24277853 0,26289577 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,24277853 0,26277205 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,24277853 0,26264845 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,24277853 0,26252497 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,24277853 0,2624016 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,24277853 0,26227835 ! chloride transport GO:0006821 67 48 0,000 0,24725193 0,26698565 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,24725193 0,26686037 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,24725193 0,2667352 ! gastrulation GO:0007369 73 48 0,000 0,24725193 0,26661015 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,24725193 0,26648521 ! regulation of endocytosis GO:0030100 63 48 0,000 0,24725193 0,26636039 ! nuclear export GO:0051168 69 48 0,000 0,24725193 0,26623569 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,24725193 0,26611111 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,25169916 0,27077085 ! sensory perception of smell GO:0007608 61 49 0,000 0,25169916 0,27064426 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,25169916 0,27051779 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,25169916 0,27039144 ! RNA elongation GO:0006354 62 49 0,000 0,25169916 0,27026521 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,25169916 0,27013909 ! germ cell development GO:0007281 68 49 0,000 0,25169916 0,2700131 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,25169916 0,26988722 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,25169916 0,26976145 ! cartilage development GO:0051216 70 49 0,000 0,25169916 0,26963581 ! maintenance of location GO:0051235 84 49 0,000 0,25169916 0,26951028 ! regulation of actin filament length GO:0030832 72 50 0,000 0,25612038 0,27411674 ! ear development GO:0043583 72 50 0,000 0,25612038 0,27398924 ! membrane fusion GO:0006944 80 50 0,000 0,25612038 0,27386186 ! proton transport GO:0015992 75 50 0,000 0,25612038 0,2737346 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,25612038 0,27360746 ! positive regulation of secretion GO:0051047 71 51 0,000 0,26051572 0,2781737 ! hydrogen transport GO:0006818 77 51 0,000 0,26051572 0,27804462 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,26051572 0,27791565 GO:0010863|positive regulation of phospholipase C activity, ! adult behavior GO:0030534 80 51 0,000 0,26051572 0,27778681 ! transition metal ion transport GO:0000041 74 52 0,000 0,26488534 0,28231524 ! regulation of cellular component size GO:0032535 74 52 0,000 0,26488534 0,28218447 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,26488534 0,28205383 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,26488534 0,28192331 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,26922939 0,28641425 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,26922939 0,28628183 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,26922939 0,28614954 ! kidney development GO:0001822 90 53 0,000 0,26922939 0,28601737 ! single fertilization GO:0007338 59 53 0,000 0,26922939 0,28588532 ! amino acid transport GO:0006865 84 54 0,000 0,27354802 0,29033708 ! glucose catabolic process GO:0006007 66 54 0,000 0,27354802 0,29020316 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,27354802 0,29006936 ! detection of external stimulus GO:0009581 66 54 0,000 0,27354802 0,28993569 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,27354802 0,28980214 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,27354802 0,28966871 ! exocytosis GO:0006887 74 55 0,000 0,27784137 0,29407968 ! mesoderm development GO:0007498 76 55 0,000 0,27784137 0,29394441 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,27784137 0,29380927 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,27784137 0,29367424 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,2821096 0,29804872 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,28635284 0,3023928 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,28635284 0,30225403 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,28635284 0,30211538 ! camera-type eye development GO:0043010 88 57 0,000 0,28635284 0,30197686 ! secondary metabolic process GO:0019748 84 57 0,000 0,28635284 0,30183846 ! developmental maturation GO:0021700 75 57 0,000 0,28635284 0,30170019 ! gonad development GO:0008406 79 57 0,000 0,28635284 0,30156205 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,29057124 0,30586446 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,29476495 0,31013695 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,29476495 0,30999514 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,2989341 0,31423603 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,2989341 0,31409248 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,2989341 0,31394906 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,2989341 0,31380577 ! regulation of heart contraction GO:0008016 91 60 0,000 0,2989341 0,31366261 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,2989341 0,31351958 ! fertilization GO:0009566 68 60 0,000 0,2989341 0,31337668 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,30307885 0,31757693 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,30307885 0,31743231 ! urogenital system development GO:0001655 101 61 0,000 0,30307885 0,31728783 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,30307885 0,31714347 ! extracellular matrix organization GO:0030198 103 61 0,000 0,30307885 0,31699925 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,30307885 0,31685516 ! amine catabolic process GO:0009310 90 62 0,000 0,30719933 0,32101702 ! neurotransmitter transport GO:0006836 81 62 0,000 0,30719933 0,32087123 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,30719933 0,32072558 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,30719933 0,32058006 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,31129568 0,32470751 ! regulation of lipase activity GO:0060191 109 63 0,000 0,31129568 0,32456032 ! appendage morphogenesis GO:0035107 93 64 0,000 0,31536805 0,32865723 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,31536805 0,32850838 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,31536805 0,32835967 ! hexose catabolic process GO:0019320 82 64 0,000 0,31536805 0,32821109 ! reproductive structure development GO:0048608 90 65 0,000 0,31941657 0,33227413 ! appendage development GO:0048736 94 65 0,000 0,31941657 0,33212392 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,31941657 0,33197384 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,31941657 0,3318239 ! defense response to bacterium GO:0042742 73 65 0,000 0,31941657 0,33167409 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,31941657 0,33152442 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,31941657 0,33137488 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,32344138 0,33539908 ! antigen processing and presentation GO:0019882 96 66 0,000 0,32344138 0,33524793 ! regulation of immune effector process GO:0002697 101 66 0,000 0,32344138 0,33509692 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,32744261 0,3390896 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,33142041 0,34305443 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,33142041 0,34290011 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,33142041 0,34274593 ! rhythmic process GO:0048511 105 68 0,000 0,33142041 0,34259189 ! inorganic anion transport GO:0015698 93 68 0,000 0,33142041 0,34243798 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,33537492 0,34636835 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,33537492 0,34621288 ! response to metal ion GO:0010038 103 70 0,000 0,33930625 0,35011412 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,33930625 0,34995712 ! eye development GO:0001654 111 70 0,000 0,33930625 0,34980026 ! amine transport GO:0015837 101 70 0,000 0,33930625 0,34964354 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,33930625 0,34948696 ! muscle cell differentiation GO:0042692 104 71 0,000 0,34321456 0,35335429 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,34321456 0,35319619 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,34321456 0,35303823 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,34709997 0,35687525 ! regulation of blood pressure GO:0008217 107 73 0,000 0,35096262 0,36068545 ! tube morphogenesis GO:0035239 118 73 0,000 0,35096262 0,36052435 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,35096262 0,36036341 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,35096262 0,3602026 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,35480264 0,3639813 ! digestion GO:0007586 97 74 0,000 0,35480264 0,36381902 ! blood coagulation GO:0007596 116 75 0,000 0,35862015 0,36756968 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,35862015 0,36740595 ! response to nutrient GO:0007584 104 75 0,000 0,35862015 0,36724237 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,35862015 0,36707893 ! amine biosynthetic process GO:0009309 97 76 0,000 0,3624153 0,37079857 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,36618821 0,37449217 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,36618821 0,37432572 ! sex differentiation GO:0007548 105 77 0,000 0,36618821 0,37415943 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,36618821 0,37399329 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,36618821 0,37382729 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,36618821 0,37366144 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,36993901 0,37732138 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,36993901 0,37715413 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,37366782 0,38078688 ! cellular respiration GO:0045333 107 79 0,000 0,37366782 0,38061824 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,37366782 0,38044975 ! regulation of lyase activity GO:0051339 133 79 0,000 0,37366782 0,38028141 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,37366782 0,38011322 ! chromatin assembly GO:0031497 102 80 0,000 0,37737478 0,38371441 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,37737478 0,38354485 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,37737478 0,38337544 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,37737478 0,38320618 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,38106001 0,38677759 ! hemostasis GO:0007599 125 81 0,000 0,38106001 0,38660698 ! regulation of neurological system process GO:0031644 122 81 0,000 0,38106001 0,38643652 ! vitamin metabolic process GO:0006766 103 81 0,000 0,38106001 0,38626621 ! ossification GO:0001503 134 82 0,000 0,38472364 0,38980809 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 0,000 0,38472364 0,38963645 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,38836579 0,39315199 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,38836579 0,39297902 ! regulation of defense response GO:0031347 117 84 0,000 0,39198659 0,39646841 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,39198659 0,39629414 ! sterol metabolic process GO:0016125 120 84 0,000 0,39198659 0,39612002 ! transcription initiation GO:0006352 118 85 0,000 0,39558617 0,39958199 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,39916464 0,40301961 ! nucleosome organization GO:0034728 114 87 0,000 0,40272212 0,40643303 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,40272212 0,40625477 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,40272212 0,40607667 ! female pregnancy GO:0007565 130 87 0,000 0,40272212 0,40589872 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,40625875 0,40928389 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,40625875 0,4091047 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,40977464 0,41246462 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,40977464 0,41228419 ! hormone metabolic process GO:0042445 121 90 0,000 0,41326991 0,41561906 ! ATP metabolic process GO:0046034 137 91 0,000 0,41674468 0,4189304 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,42019907 0,42221837 ! DNA recombination GO:0006310 146 92 0,000 0,42019907 0,422034 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,4236332 0,4252974 ! electron transport chain GO:0022900 123 94 0,000 0,42704718 0,42853775 ! carboxylic acid transport GO:0046942 147 95 0,000 0,43044114 0,43175518 GO:0015849|organic acid transport, ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,43716944 0,43831286 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,43716944 0,43812188 ! calcium ion transport GO:0006816 167 99 0,000 0,44381902 0,44459222 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,44711457 0,44769853 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,44711457 0,44750371 ! divalent metal ion transport GO:0070838 171 100 0,000 0,44711457 0,44730906 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,44711457 0,44711457