pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6849-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 156 86 9,000 5,016E-10 1,154E-06 ! interphase GO:0051325 159 88 9,000 6,319E-10 7,266E-07 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 5,000 5,607E-09 4,299E-06 ! induction of apoptosis by extracellular signals GO:0008624 74 44 6,000 2,347E-08 1,35E-05 ! negative regulation of protein kinase activity GO:0006469 99 57 6,000 1,501E-07 6,903E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 3,000 1,651E-07 6,329E-05 ! S phase GO:0051320 8 8 3,000 1,651E-07 5,425E-05 GO:0000084|S phase of mitotic cell cycle, ! negative regulation of kinase activity GO:0033673 100 58 6,000 1,697E-07 4,878E-05 ! negative regulation of transferase activity GO:0051348 105 61 6,000 2,419E-07 6,181E-05 ! induction of apoptosis by intracellular signals GO:0008629 67 40 5,000 3,553E-07 8,171E-05 ! regulation of B cell proliferation GO:0030888 15 10 3,000 4,899E-07 1,024E-04 ! negative regulation of phosphorylation GO:0042326 41 23 4,000 5,029E-07 9,639E-05 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 5,000 5,546E-07 9,812E-05 ! negative regulation of mast cell proliferation GO:0070667 17 11 3,000 7,657E-07 1,258E-04 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of phosphorus metabolic process GO:0010563 45 25 4,000 7,851E-07 1,204E-04 GO:0045936|negative regulation of phosphate metabolic process, ! mitotic sister chromatid segregation GO:0000070 45 32 4,000 2,86E-06 4,111E-04 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 3,000 3,098E-06 4,192E-04 ! negative regulation of leukocyte proliferation GO:0070664 25 15 3,000 3,098E-06 3,959E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! sister chromatid segregation GO:0000819 46 33 4,000 3,351E-06 4,057E-04 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 6,832E-06 7,856E-04 ! negative regulation of T cell activation GO:0050868 25 18 3,000 6,832E-06 7,482E-04 ! negative regulation of B cell activation GO:0050869 9 6 2,000 6,859E-06 7,17E-04 ! cell structure disassembly during apoptosis GO:0006921 24 19 3,000 8,606E-06 8,606E-04 ! apoptotic nuclear changes GO:0030262 24 19 3,000 8,606E-06 8,248E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,194E-05 1,099E-03 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 3,000 1,314E-05 1,163E-03 ! regulation of mast cell proliferation GO:0070666 64 44 4,000 1,441E-05 1,227E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 1,901E-05 1,561E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 1,901E-05 1,507E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,901E-05 1,457E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 4,000 2,001E-05 1,484E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 3,000 2,718E-05 1,953E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 2,836E-05 1,977E-03 ! negative regulation of BMP signaling pathway GO:0030514 13 9 2,000 2,836E-05 1,919E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 2,995E-05 1,968E-03 ! regulation of DNA metabolic process GO:0051052 135 85 5,000 3,121E-05 1,994E-03 ! cell cycle arrest GO:0007050 150 86 5,000 3,336E-05 2,074E-03 ! negative regulation of leukocyte activation GO:0002695 39 27 3,000 3,729E-05 2,257E-03 ! cell junction assembly GO:0034329 56 28 3,000 4,327E-05 2,552E-03 ! regulation of B cell activation GO:0050864 42 28 3,000 4,327E-05 2,488E-03 ! chromosome segregation GO:0007059 83 57 4,000 5,161E-05 2,895E-03 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 5,513E-05 3,019E-03 GO:0050927|positive regulation of positive chemotaxis, ! chondrocyte differentiation GO:0002062 17 11 2,000 5,513E-05 2,949E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 5,513E-05 2,882E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of cell activation GO:0050866 44 30 3,000 5,728E-05 2,928E-03 ! cell junction organization GO:0034330 63 33 3,000 8,414E-05 4,207E-03 ! nucleus organization GO:0006997 49 33 3,000 8,414E-05 4,118E-03 ! cell cycle checkpoint GO:0000075 108 64 4,000 9,033E-05 4,329E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 4,000 9,033E-05 4,24E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 9,458E-05 4,35E-03 ! induction of apoptosis via death domain receptors GO:0008625 15 13 2,000 9,458E-05 4,265E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,197E-04 5,296E-03 ! positive regulation of phosphorylation GO:0042327 102 70 4,000 1,386E-04 6,016E-03 ! regulation of T cell proliferation GO:0042129 58 38 3,000 1,477E-04 6,29E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,489E-04 6,227E-03 ! regulation of BMP signaling pathway GO:0030510 21 15 2,000 1,489E-04 6,116E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 4,000 1,584E-04 6,394E-03 GO:0045937|positive regulation of phosphate metabolic process, ! G1 phase GO:0051318 27 16 2,000 1,823E-04 7,23E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 1,823E-04 7,107E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 2,000 1,823E-04 6,989E-03 ! cellular component disassembly GO:0022411 64 42 3,000 2,191E-04 8,261E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,202E-04 8,17E-03 ! cell-substrate junction assembly GO:0007044 39 17 2,000 2,202E-04 8,041E-03 ! positive regulation of protein modification process GO:0031401 107 78 4,000 2,311E-04 8,306E-03 ! glycolysis GO:0006096 53 44 3,000 2,628E-04 9,3E-03 ! regulation of glucose import GO:0046324 21 18 2,000 2,629E-04 9,163E-03 GO:0010827|regulation of glucose transport, ! negative regulation of immune system process GO:0002683 73 47 3,000 3,397E-04 0,01166188 ! pallium development GO:0021543 38 20 2,000 3,635E-04 0,01229627 ! positive regulation of locomotion GO:0040017 35 20 2,000 3,635E-04 0,01211807 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 2,000 3,635E-04 0,01194495 ! regulation of DNA replication GO:0006275 75 48 3,000 3,686E-04 0,01193992 ! regulation of chemotaxis GO:0050920 36 21 2,000 4,219E-04 0,01347869 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 4,219E-04 0,01329405 ! regulation of behavior GO:0050795 38 22 2,000 4,86E-04 0,01510669 ! blastocyst development GO:0001824 37 22 2,000 4,86E-04 0,01490527 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 4,921E-04 0,01489397 ! glial cell fate commitment GO:0021781 12 5 1,000 4,921E-04 0,01470055 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 1,000 4,921E-04 0,01451208 ! skeletal myofibril assembly GO:0014866 7 5 1,000 4,921E-04 0,01432838 ! epithelial cell proliferation GO:0050673 6 5 1,000 4,921E-04 0,01414927 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 4,921E-04 0,01397459 ! induction of apoptosis by oxidative stress GO:0008631 5 5 1,000 4,921E-04 0,01380417 ! peptidyl-histidine phosphorylation GO:0018106 7 5 1,000 4,921E-04 0,01363786 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 4,921E-04 0,0134755 GO:0045686|negative regulation of glial cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 1,000 4,921E-04 0,01331696 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 4,921E-04 0,01316212 ! peptidyl-amino acid modification GO:0018193 147 93 4,000 5,229E-04 0,01382266 ! myelination GO:0042552 35 23 2,000 5,561E-04 0,01453345 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 5,561E-04 0,01437016 ! glucose catabolic process GO:0006007 66 54 3,000 5,797E-04 0,01481583 ! DNA catabolic process GO:0006308 67 54 3,000 5,797E-04 0,01465302 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 6,322E-04 0,01580552 ! developmental maturation GO:0021700 75 57 3,000 7,124E-04 0,01761797 ! regulation of chromosome organization GO:0033044 35 25 2,000 7,147E-04 0,01748799 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 7,147E-04 0,01730391 ! erythrocyte maturation GO:0043249 6 6 1,000 7,348E-04 0,01760443 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 7,348E-04 0,01742294 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 7,348E-04 0,01724516 ! neuron apoptosis GO:0051402 8 6 1,000 7,348E-04 0,01707096 ! wound healing, spreading of epidermal cells GO:0035313 10 6 1,000 7,348E-04 0,01690026 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 7,348E-04 0,01673293 ! peptidyl-histidine modification GO:0018202 9 6 1,000 7,348E-04 0,01656888 ! blastocyst growth GO:0001832 15 6 1,000 7,348E-04 0,01640801 ! negative regulation of protein modification process GO:0031400 50 26 2,000 8,038E-04 0,01777602 ! homeostasis of number of cells GO:0048872 84 61 3,000 9,208E-04 0,02017081 ! negative regulation of cell growth GO:0030308 106 62 3,000 9,79E-04 0,02124245 ! erythrocyte differentiation GO:0030218 38 28 2,000 1,002E-03 0,02154597 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,002E-03 0,02134647 ! ensheathment of neurons GO:0007272 43 28 2,000 1,002E-03 0,02115063 GO:0008366|axon ensheathment, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,024E-03 0,02140955 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,024E-03 0,02121667 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 1,024E-03 0,02102724 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,024E-03 0,02084116 ! lipoprotein transport GO:0042953 9 7 1,000 1,024E-03 0,02065834 ! hemoglobin metabolic process GO:0020027 10 7 1,000 1,024E-03 0,0204787 ! cardiac muscle cell development GO:0055013 9 7 1,000 1,024E-03 0,02030216 ! synaptic vesicle endocytosis GO:0048488 16 7 1,000 1,024E-03 0,02012864 ! neuroblast proliferation GO:0007405 13 7 1,000 1,024E-03 0,01995806 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 1,024E-03 0,01979034 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 1,000 1,024E-03 0,01962542 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 1,04E-03 0,01976279 ! negative regulation of cell size GO:0045792 108 64 3,000 1,103E-03 0,02079399 ! hexose catabolic process GO:0019320 82 64 3,000 1,103E-03 0,02062493 ! telencephalon development GO:0021537 52 29 2,000 1,112E-03 0,02063049 ! spindle organization GO:0007051 37 30 2,000 1,229E-03 0,02262227 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 2,000 1,354E-03 0,02471938 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,354E-03 0,02452474 GO:0060326|cell chemotaxis, ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 1,359E-03 0,02441794 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 1,000 1,359E-03 0,02422866 GO:0046579|positive regulation of Ras protein signal transduction, ! cell proliferation in forebrain GO:0021846 10 8 1,000 1,359E-03 0,02404228 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,359E-03 0,02385875 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,359E-03 0,023678 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,359E-03 0,02349997 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,359E-03 0,0233246 ! regulation of gliogenesis GO:0014013 20 8 1,000 1,359E-03 0,02315183 GO:0045685|regulation of glial cell differentiation, ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,359E-03 0,02298159 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,359E-03 0,02281384 ! branched chain family amino acid catabolic process GO:0009083 11 8 1,000 1,359E-03 0,02264853 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,359E-03 0,02248559 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 1,359E-03 0,02232498 GO:0000076|DNA replication checkpoint, ! monosaccharide catabolic process GO:0046365 91 71 3,000 1,624E-03 0,02648566 ! SMAD protein nuclear translocation GO:0007184 15 9 1,000 1,739E-03 0,02816802 ! regulation of activated T cell proliferation GO:0046006 15 9 1,000 1,739E-03 0,02797104 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 1,000 1,739E-03 0,0277768 ! L-serine metabolic process GO:0006563 13 9 1,000 1,739E-03 0,02758523 ! motor axon guidance GO:0008045 14 9 1,000 1,739E-03 0,02739629 ! erythrocyte development GO:0048821 11 9 1,000 1,739E-03 0,02720992 ! regulation of DNA replication initiation GO:0030174 13 9 1,000 1,739E-03 0,02702607 ! blastocyst formation GO:0001825 12 9 1,000 1,739E-03 0,02684469 ! embryonic placenta development GO:0001892 12 9 1,000 1,739E-03 0,02666572 ! nucleus localization GO:0051647 15 9 1,000 1,739E-03 0,02648913 ! DNA integrity checkpoint GO:0031570 57 34 2,000 1,775E-03 0,02685995 ! erythrocyte homeostasis GO:0034101 45 34 2,000 1,775E-03 0,02668439 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,775E-03 0,02651112 ! negative regulation of transport GO:0051051 116 73 3,000 1,799E-03 0,02669773 ! mitochondrion organization GO:0007005 104 73 3,000 1,799E-03 0,02652659 ! keratinocyte differentiation GO:0030216 47 35 2,000 1,932E-03 0,02829621 ! regulation of action potential in neuron GO:0019228 54 35 2,000 1,932E-03 0,02811712 ! negative regulation of growth GO:0045926 123 75 3,000 1,987E-03 0,02874922 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 2,164E-03 0,03110405 ! hippocampus development GO:0021766 19 10 1,000 2,164E-03 0,03091086 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,164E-03 0,03072005 GO:0010812|negative regulation of cell-substrate adhesion, ! pathogenesis GO:0009405 13 10 1,000 2,164E-03 0,03053158 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 2,164E-03 0,03034542 ! striated muscle cell differentiation GO:0051146 54 38 2,000 2,451E-03 0,03417104 ! pigmentation GO:0043473 74 38 2,000 2,451E-03 0,03396519 ! alcohol catabolic process GO:0046164 104 80 3,000 2,517E-03 0,03466339 ! forebrain development GO:0030900 131 80 3,000 2,517E-03 0,03445706 ! detection of mechanical stimulus GO:0050982 15 11 1,000 2,632E-03 0,0358248 ! focal adhesion formation GO:0048041 24 11 1,000 2,632E-03 0,03561407 ! chromatin silencing GO:0006342 19 11 1,000 2,632E-03 0,0354058 ! T cell homeostasis GO:0043029 20 11 1,000 2,632E-03 0,03519995 ! serine family amino acid biosynthetic process GO:0009070 13 11 1,000 2,632E-03 0,03499648 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 2,000 2,642E-03 0,0349236 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 2,842E-03 0,03734677 ! epidermal cell differentiation GO:0009913 53 40 2,000 2,842E-03 0,03713458 ! microtubule cytoskeleton organization GO:0000226 120 84 3,000 3,005E-03 0,03904319 ! regulation of T cell differentiation GO:0045580 59 41 2,000 3,05E-03 0,03941275 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 1,000 3,144E-03 0,04040017 ! Golgi organization GO:0007030 18 12 1,000 3,144E-03 0,04017572 ! cell-cell junction assembly GO:0007043 18 12 1,000 3,144E-03 0,03995376 ! leukocyte migration GO:0050900 60 43 2,000 3,495E-03 0,04416838 ! activation of caspase activity GO:0006919 65 43 2,000 3,495E-03 0,04392702 ! response to insulin stimulus GO:0032868 63 43 2,000 3,495E-03 0,04368828 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 3,699E-03 0,04598336 ! lymphocyte homeostasis GO:0002260 24 13 1,000 3,699E-03 0,04573614 ! regulation of T cell activation GO:0050863 128 89 3,000 3,7E-03 0,04551388 ! regulation of action potential GO:0001508 71 44 2,000 3,732E-03 0,04565216 ! regulation of inflammatory response GO:0050727 60 44 2,000 3,732E-03 0,04541061 ! positive regulation of cell cycle GO:0045787 77 45 2,000 3,978E-03 0,04815009 ! positive regulation of defense response GO:0031349 59 45 2,000 3,978E-03 0,04789799 ! cell maturation GO:0048469 60 45 2,000 3,978E-03 0,04764852 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 3,978E-03 0,04740164 ! response to UV GO:0009411 75 46 2,000 4,233E-03 0,05018886 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 4,295E-03 0,05066072 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,295E-03 0,05040225 ! heterophilic cell adhesion GO:0007157 29 14 1,000 4,295E-03 0,0501464 ! limbic system development GO:0021761 25 14 1,000 4,295E-03 0,04989313 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 1,000 4,295E-03 0,04964241 ! epidermis morphogenesis GO:0048730 29 14 1,000 4,295E-03 0,0493942 ! embryo implantation GO:0007566 27 14 1,000 4,295E-03 0,04914846 ! carbohydrate catabolic process GO:0016052 121 93 3,000 4,33E-03 0,04930531 ! positive regulation of caspase activity GO:0043280 72 48 2,000 4,774E-03 0,05409126 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 4,774E-03 0,05382611 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 4,774E-03 0,05356354 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 4,933E-03 0,05507753 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 4,933E-03 0,05481146 ! lipid phosphorylation GO:0046834 23 15 1,000 4,933E-03 0,05454794 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 4,933E-03 0,05428695 ! regulation of survival gene product expression GO:0045884 20 15 1,000 4,933E-03 0,05402844 ! cerebral cortex development GO:0021987 29 15 1,000 4,933E-03 0,05377238 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 4,933E-03 0,05351873 ! cartilage development GO:0051216 70 49 2,000 5,059E-03 0,05463274 ! lipid modification GO:0030258 73 50 2,000 5,355E-03 0,05755233 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 3,000 5,405E-03 0,05781817 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 1,000 5,612E-03 0,05975425 ! DNA replication initiation GO:0006270 25 16 1,000 5,612E-03 0,05947889 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 5,612E-03 0,05920605 ! negative regulation of translation GO:0017148 22 16 1,000 5,612E-03 0,0589357 ! memory GO:0007613 25 17 1,000 6,331E-03 0,06618318 ! actin filament bundle formation GO:0051017 26 17 1,000 6,331E-03 0,0658837 ! neuromuscular junction development GO:0007528 23 17 1,000 6,331E-03 0,06558693 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 6,331E-03 0,06529282 ! peptidyl-serine modification GO:0018209 27 17 1,000 6,331E-03 0,06500133 ! cell-cell junction organization GO:0045216 25 17 1,000 6,331E-03 0,06471244 ! cytokine-mediated signaling pathway GO:0019221 76 54 2,000 6,639E-03 0,06756612 ! positive regulation of DNA replication GO:0045740 29 18 1,000 7,089E-03 0,07182707 ! pigmentation during development GO:0048066 31 18 1,000 7,089E-03 0,07151203 ! heart process GO:0003015 27 18 1,000 7,089E-03 0,07119975 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 1,000 7,089E-03 0,07089019 GO:0006692|prostanoid metabolic process, ! synaptic vesicle transport GO:0048489 33 18 1,000 7,089E-03 0,07058331 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 7,089E-03 0,07027907 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 7,089E-03 0,06997744 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 7,344E-03 0,07218468 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 7,712E-03 0,07548336 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 7,886E-03 0,07685975 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 7,886E-03 0,07653544 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 7,886E-03 0,07621387 ! response to alkaloid GO:0043279 32 19 1,000 7,886E-03 0,07589498 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 7,886E-03 0,07557875 ! plasma membrane fusion GO:0045026 23 19 1,000 7,886E-03 0,07526515 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 7,886E-03 0,07495413 ! actin filament organization GO:0007015 95 59 2,000 8,482E-03 0,08027837 ! myeloid cell differentiation GO:0030099 85 59 2,000 8,482E-03 0,07994936 ! hindlimb morphogenesis GO:0035137 32 20 1,000 8,722E-03 0,08188338 ! fatty acid beta-oxidation GO:0006635 31 20 1,000 8,722E-03 0,08155052 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 8,722E-03 0,08122036 ! positive regulation of B cell activation GO:0050871 31 20 1,000 8,722E-03 0,08089286 ! actin filament-based movement GO:0030048 34 20 1,000 8,722E-03 0,08056798 ! regulation of heart contraction GO:0008016 91 60 2,000 8,882E-03 0,08171853 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 9,596E-03 0,08793228 ! protein amino acid acylation GO:0043543 37 21 1,000 9,596E-03 0,08758335 ! regulation of DNA recombination GO:0000018 40 21 1,000 9,596E-03 0,08723717 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 1,000 9,596E-03 0,08689371 GO:0060415|muscle tissue morphogenesis, ! platelet activation GO:0030168 28 21 1,000 9,596E-03 0,08655295 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 9,596E-03 0,08621486 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 9,596E-03 0,08587939 GO:0006099|tricarboxylic acid cycle, ! organelle localization GO:0051640 96 62 2,000 9,717E-03 0,08662501 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 0,01050709 0,09330623 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 0,01050709 0,09294736 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01050709 0,09259124 ! leukocyte adhesion GO:0007159 38 22 1,000 0,01050709 0,09223784 ! vasculogenesis GO:0001570 33 22 1,000 0,01050709 0,09188713 ! microtubule organizing center organization GO:0031023 28 22 1,000 0,01050709 0,09153907 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,01050709 0,09119364 GO:0010810|regulation of cell-substrate adhesion, ! coenzyme catabolic process GO:0009109 33 22 1,000 0,01050709 0,0908508 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01050709 0,09051054 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01105206 0,09484977 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01145481 0,09794076 ! acetyl-CoA metabolic process GO:0006084 33 23 1,000 0,01145481 0,09757801 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01145481 0,09721795 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 0,01145481 0,09686053 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01145481 0,09650573 ! cell fate determination GO:0001709 45 23 1,000 0,01145481 0,09615352 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01199803 0,10034714 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01243868 0,10365568 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 0,01243868 0,10328148 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 0,01243868 0,10290996 ! learning or memory GO:0007611 123 68 2,000 0,01248794 0,10294716 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01345816 0,11054914 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01345816 0,11015573 GO:0045840|positive regulation of mitosis, ! muscle cell differentiation GO:0042692 104 71 2,000 0,01402585 0,11439521 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 0,01402585 0,11399099 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01451269 0,11753233 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,01456132 0,11751244 ! myofibril assembly GO:0030239 36 27 1,000 0,01560173 0,12546849 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 1,000 0,01560173 0,12503132 ! response to ionizing radiation GO:0010212 47 27 1,000 0,01560173 0,12459719 ! lipid oxidation GO:0034440 38 27 1,000 0,01560173 0,12416605 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 1,000 0,01560173 0,12373789 ! serine family amino acid metabolic process GO:0009069 37 27 1,000 0,01560173 0,12331268 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01560173 0,12289037 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 0,01560173 0,12247095 ! gene silencing GO:0016458 41 27 1,000 0,01560173 0,12205439 ! protein import into nucleus GO:0006606 118 74 2,000 0,01566672 0,12214731 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 0,01566672 0,12173465 ! regulation of ligase activity GO:0051340 114 75 2,000 0,01623669 0,12573867 ! nuclear import GO:0051170 121 75 2,000 0,01623669 0,12531673 ! placenta development GO:0001890 37 28 1,000 0,01672476 0,12865203 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01788125 0,13708955 ! muscle cell development GO:0055001 38 29 1,000 0,01788125 0,13663411 ! hindbrain development GO:0030902 45 30 1,000 0,01907066 0,14524011 ! fatty acid catabolic process GO:0009062 43 30 1,000 0,01907066 0,14476077 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01907066 0,14428459 ! protein localization in nucleus GO:0034504 133 80 2,000 0,01926008 0,14523992 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,01989957 0,14957192 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,02029248 0,15202838 ! mammary gland development GO:0030879 57 31 1,000 0,02029248 0,15153478 ! glial cell differentiation GO:0010001 55 31 1,000 0,02029248 0,15104438 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,02029248 0,15055714 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,02029248 0,15007303 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02029248 0,14959203 ! regulation of cell adhesion GO:0030155 159 83 2,000 0,02121345 0,15588158 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,02154621 0,15782256 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,02154621 0,15732153 ! meiosis I GO:0007127 52 32 1,000 0,02154621 0,15682368 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,02154621 0,15632897 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02154621 0,15583737 ! regulation of protein stability GO:0031647 48 32 1,000 0,02154621 0,15534885 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,02154621 0,15486338 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02154621 0,15438094 ! regulation of defense response GO:0031347 117 84 2,000 0,02188785 0,15634179 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,0225739 0,16074291 ! regulation of membrane potential GO:0042391 128 85 2,000 0,0225739 0,16024679 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02283133 0,16157557 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02283133 0,16107994 ! ear morphogenesis GO:0042471 42 33 1,000 0,02283133 0,16058734 ! actomyosin structure organization GO:0031032 43 33 1,000 0,02283133 0,16009775 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,02283133 0,15961113 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,02283133 0,15912746 ! cytokinesis GO:0000910 52 33 1,000 0,02283133 0,15864671 ! female pregnancy GO:0007565 130 87 2,000 0,02398092 0,16613287 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,02414735 0,16678347 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,02414735 0,16628412 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,02414735 0,16578775 ! aerobic respiration GO:0009060 47 34 1,000 0,02414735 0,16529433 ! carboxylic acid catabolic process GO:0046395 122 88 2,000 0,02470189 0,16858857 GO:0016054|organic acid catabolic process, ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,02549376 0,17347824 ! maintenance of protein location GO:0045185 65 35 1,000 0,02549376 0,17296651 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,02549376 0,17245778 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of binding GO:0051100 58 36 1,000 0,02687008 0,18123515 ! cell fate commitment GO:0045165 141 92 2,000 0,02770205 0,18630034 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,02827583 0,18960467 ! learning GO:0007612 67 37 1,000 0,02827583 0,1890535 ! gliogenesis GO:0042063 71 38 1,000 0,02971052 0,19807012 ! maintenance of location in cell GO:0051651 69 38 1,000 0,02971052 0,19749766 ! regulation of response to external stimulus GO:0032101 139 96 2,000 0,03088771 0,20473123 ! in utero embryonic development GO:0001701 147 96 2,000 0,03088771 0,20414292 ! response to light stimulus GO:0009416 153 96 2,000 0,03088771 0,20355799 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,03117368 0,2048556 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 1,000 0,03117368 0,20427197 ! developmental growth GO:0048589 62 39 1,000 0,03117368 0,20369165 ! cell growth GO:0016049 61 39 1,000 0,03117368 0,20311462 ! synapse organization GO:0050808 55 39 1,000 0,03117368 0,20254085 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 0,031713 0,20546449 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,03266484 0,21103689 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 0,03266484 0,21044575 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,03266484 0,20985791 ! protein import GO:0017038 156 99 2,000 0,03339808 0,21397096 ! protein amino acid lipidation GO:0006497 62 41 1,000 0,03418354 0,21839483 ! glucose transport GO:0015758 52 41 1,000 0,03418354 0,21778986 ! protein localization in organelle GO:0033365 161 100 2,000 0,03425782 0,2176602 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03496944 0,22156947 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03496944 0,22096076 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03496944 0,22035539 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03496944 0,21975332 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03496944 0,21915454 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03496944 0,21855901 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03496944 0,21796671 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03496944 0,21737761 ! sleep GO:0030431 11 5 0,000 0,03496944 0,21679169 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03496944 0,21620891 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03496944 0,21562927 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03496944 0,21505272 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03496944 0,21447924 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03496944 0,21390882 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03496944 0,21334142 ! tongue development GO:0043586 6 5 0,000 0,03496944 0,21277703 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03496944 0,21221561 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03496944 0,21165715 ! cobalt ion transport GO:0006824 9 5 0,000 0,03496944 0,21110162 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03496944 0,210549 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03496944 0,20999926 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03496944 0,20945239 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03496944 0,20890835 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03496944 0,20836714 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03496944 0,20782872 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03496944 0,20729308 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03496944 0,2067602 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03496944 0,20623004 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03496944 0,2057026 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03496944 0,20517785 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03496944 0,20465577 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,03496944 0,20413634 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03496944 0,20361953 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03496944 0,20310534 ! malate metabolic process GO:0006108 7 5 0,000 0,03496944 0,20259374 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03496944 0,20208471 ! behavioral response to pain GO:0048266 7 5 0,000 0,03496944 0,20157824 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03496944 0,20107429 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03496944 0,20057286 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03496944 0,20007392 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03496944 0,19957746 ! mating behavior GO:0007617 6 5 0,000 0,03496944 0,19908346 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03496944 0,19859189 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03496944 0,19810275 ! rhythmic behavior GO:0007622 12 5 0,000 0,03496944 0,19761601 ! copulation GO:0007620 7 5 0,000 0,03496944 0,19713166 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03496944 0,19664967 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03496944 0,19617004 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03496944 0,19569274 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03496944 0,19521776 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03496944 0,19474508 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03496944 0,19427468 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03496944 0,19380655 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03496944 0,19334066 ! response to protozoan GO:0001562 9 5 0,000 0,03496944 0,19287702 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03496944 0,19241559 ! lymph vessel development GO:0001945 7 5 0,000 0,03496944 0,19195636 ! endochondral ossification GO:0001958 12 5 0,000 0,03496944 0,19149932 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03496944 0,19104446 ! parathyroid gland development GO:0060017 8 5 0,000 0,03496944 0,19059174 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03496944 0,19014117 ! anagen GO:0042640 6 5 0,000 0,03496944 0,18969273 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03496944 0,18924639 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03496944 0,18880215 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03496944 0,18835999 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03496944 0,1879199 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03496944 0,18748186 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03496944 0,18704585 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03496944 0,18661187 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03496944 0,1861799 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03496944 0,18574992 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03496944 0,18532193 ! ovulation GO:0030728 6 5 0,000 0,03496944 0,1848959 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03496944 0,18447183 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,03496944 0,18404969 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,03496944 0,18362949 ! response to pH GO:0009268 9 5 0,000 0,03496944 0,1832112 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03496944 0,18279481 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03496944 0,18238031 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03496944 0,18196768 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03496944 0,18155692 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03496944 0,18114801 ! polyol catabolic process GO:0046174 7 5 0,000 0,03496944 0,18074094 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03496944 0,18033569 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03496944 0,17993225 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03496944 0,17953062 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03496944 0,17913077 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03496944 0,1787327 ! urea metabolic process GO:0019627 6 5 0,000 0,03496944 0,1783364 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03496944 0,17794185 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03496944 0,17754904 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03496944 0,17715797 ! neutrophil activation GO:0042119 5 5 0,000 0,03496944 0,17676861 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03496944 0,17638096 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03496944 0,175995 ! response to food GO:0032094 5 5 0,000 0,03496944 0,17561073 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03496944 0,17522814 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03496944 0,17484721 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03496944 0,17446793 ! forebrain neuron development GO:0021884 7 5 0,000 0,03496944 0,1740903 ! melanosome organization GO:0032438 7 5 0,000 0,03496944 0,17371429 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03496944 0,17333991 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03496944 0,17296713 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03496944 0,17259596 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03496944 0,17222637 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03496944 0,17185837 ! nucleoside transport GO:0015858 6 5 0,000 0,03496944 0,17149193 ! nucleoside salvage GO:0043174 7 5 0,000 0,03496944 0,17112706 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03496944 0,17076373 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03496944 0,17040194 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03496944 0,17004168 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03496944 0,16968295 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03496944 0,16932572 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03496944 0,16896999 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03496944 0,16861576 ! depyrimidination GO:0045008 8 5 0,000 0,03496944 0,168263 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03496944 0,16791173 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03496944 0,16756191 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03496944 0,16721355 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03496944 0,16686663 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03496944 0,16652115 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03496944 0,1661771 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03496944 0,16583447 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03496944 0,16549324 ! monocyte differentiation GO:0030224 8 5 0,000 0,03496944 0,16515342 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03496944 0,16481499 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03496944 0,16447795 ! centrosome duplication GO:0051298 5 5 0,000 0,03496944 0,16414228 ! response to UV-C GO:0010225 6 5 0,000 0,03496944 0,16380798 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03496944 0,16347503 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03496944 0,16314344 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! regulation of dendrite development GO:0050773 12 5 0,000 0,03496944 0,16281319 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03496944 0,16248428 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03496944 0,16215669 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03496944 0,16183042 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03496944 0,16150545 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03496944 0,1611818 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03496944 0,16085943 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03496944 0,16053836 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03496944 0,16021856 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03496944 0,15990003 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03496944 0,15958277 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03496944 0,15926676 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03496944 0,15895201 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03496944 0,15863849 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03496944 0,15832621 ! neural tube patterning GO:0021532 6 5 0,000 0,03496944 0,15801516 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03496944 0,15770533 ! histone demethylation GO:0016577 9 5 0,000 0,03496944 0,15739671 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03496944 0,15708929 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03496944 0,15678307 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03496944 0,15647805 ! enteric nervous system development GO:0048484 8 5 0,000 0,03496944 0,15617421 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03496944 0,15587154 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03496944 0,15557005 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03496944 0,15526972 ! transcription termination GO:0006353 8 5 0,000 0,03496944 0,15497055 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03496944 0,15467253 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03496944 0,15437566 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03496944 0,15407992 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03496944 0,15378531 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03496944 0,15349183 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03496944 0,15319946 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03496944 0,15290821 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03496944 0,15261806 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03496944 0,15232901 ! apical protein localization GO:0045176 6 5 0,000 0,03496944 0,15204105 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03496944 0,15175418 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03496944 0,15146839 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03496944 0,15118368 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03496944 0,15090003 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03496944 0,15061745 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03496944 0,15033592 ! glial cell migration GO:0008347 10 5 0,000 0,03496944 0,15005544 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03496944 0,14977601 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03496944 0,14949761 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03496944 0,14922025 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03496944 0,14894392 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03496944 0,14866861 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03496944 0,14839431 ! neural plate development GO:0001840 6 5 0,000 0,03496944 0,14812102 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03496944 0,14784874 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03496944 0,14757746 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03496944 0,14730717 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03496944 0,14703787 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03496944 0,14676956 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03496944 0,14650222 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03496944 0,14623585 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03496944 0,14597045 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03496944 0,14570601 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03496944 0,14544252 ! spindle assembly GO:0051225 5 5 0,000 0,03496944 0,14517999 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03496944 0,14491841 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03496944 0,14465776 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03496944 0,14439805 ! organ regeneration GO:0031100 7 5 0,000 0,03496944 0,14413928 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03496944 0,14388142 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03496944 0,14362449 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03496944 0,14336848 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03496944 0,14311337 GO:0055081|anion homeostasis, ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,03572932 0,14596346 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,03572932 0,14570466 ! hexose transport GO:0008645 54 42 1,000 0,03572932 0,14544678 GO:0015749|monosaccharide transport, ! icosanoid metabolic process GO:0006690 61 42 1,000 0,03572932 0,14518981 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,03572932 0,14493374 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,03730172 0,1510457 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 0,03730172 0,15078024 ! vesicle organization GO:0016050 79 43 1,000 0,03730172 0,15051571 ! cellular amino acid biosynthetic process GO:0008652 51 44 1,000 0,0389003 0,15669122 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,0389003 0,15641728 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,0389003 0,1561443 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 0,04052461 0,16238084 ! tRNA transcription GO:0009304 11 6 0,000 0,04181637 0,16726549 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04181637 0,16697509 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04181637 0,16668571 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04181637 0,16639733 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04181637 0,16610994 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04181637 0,16582354 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04181637 0,16553813 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04181637 0,1652537 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04181637 0,16497025 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04181637 0,16468776 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04181637 0,16440625 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04181637 0,16412569 ! prostate gland development GO:0030850 9 6 0,000 0,04181637 0,16384609 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04181637 0,16356744 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04181637 0,16328974 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04181637 0,16301297 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04181637 0,16273715 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04181637 0,16246225 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04181637 0,16218829 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04181637 0,16191524 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04181637 0,16164312 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04181637 0,1613719 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,04181637 0,1611016 ! neuron adhesion GO:0007158 9 6 0,000 0,04181637 0,1608322 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,04181637 0,1605637 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04181637 0,16029609 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04181637 0,16002938 ! signal peptide processing GO:0006465 8 6 0,000 0,04181637 0,15976355 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04181637 0,1594986 ! mRNA stabilization GO:0048255 15 6 0,000 0,04181637 0,15923453 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04181637 0,15897133 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04181637 0,158709 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04181637 0,15844754 ! opsonization GO:0008228 8 6 0,000 0,04181637 0,15818693 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04181637 0,15792718 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04181637 0,15766829 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04181637 0,15741024 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04181637 0,15715303 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04181637 0,15689666 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04181637 0,15664113 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04181637 0,15638643 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04181637 0,15613256 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04181637 0,1558795 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04181637 0,15562727 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04181637 0,15537586 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04181637 0,15512525 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04181637 0,15487545 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04181637 0,15462645 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04181637 0,15437826 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04181637 0,15413086 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04181637 0,15388425 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04181637 0,15363843 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04181637 0,15339339 ! thymic T cell selection GO:0045061 12 6 0,000 0,04181637 0,15314913 ! protein lipoylation GO:0009249 10 6 0,000 0,04181637 0,15290565 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04181637 0,15266294 ! pigment granule organization GO:0048753 11 6 0,000 0,04181637 0,15242101 ! drug transport GO:0015893 6 6 0,000 0,04181637 0,15217983 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04181637 0,15193942 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04181637 0,15169977 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04181637 0,15146087 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04181637 0,15122273 ! histidine metabolic process GO:0006547 6 6 0,000 0,04181637 0,15098533 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04181637 0,15074867 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04181637 0,15051276 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04181637 0,15027759 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04181637 0,15004314 ! adenohypophysis development GO:0021984 10 6 0,000 0,04181637 0,14980943 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04181637 0,14957645 ! hyperosmotic response GO:0006972 8 6 0,000 0,04181637 0,14934418 ! microtubule nucleation GO:0007020 10 6 0,000 0,04181637 0,14911264 ! ER overload response GO:0006983 7 6 0,000 0,04181637 0,14888182 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04181637 0,14865171 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04181637 0,14842231 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04181637 0,14819361 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04181637 0,14796562 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04181637 0,14773833 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04181637 0,14751174 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04181637 0,14728584 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04181637 0,14706063 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04181637 0,14683611 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04181637 0,14661228 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04181637 0,14638912 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04181637 0,14616665 ! organic alcohol transport GO:0015850 9 6 0,000 0,04181637 0,14594485 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04181637 0,14572372 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04181637 0,14550326 ! male sex determination GO:0030238 9 6 0,000 0,04181637 0,14528347 ! carnitine transport GO:0015879 8 6 0,000 0,04181637 0,14506434 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04181637 0,14484587 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04181637 0,14462805 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04181637 0,14441089 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04181637 0,14419438 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04181637 0,14397852 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04181637 0,14376331 ! parturition GO:0007567 12 6 0,000 0,04181637 0,14354874 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04181637 0,14333481 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04181637 0,14312151 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04181637 0,14290885 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04181637 0,14269682 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04181637 0,14248541 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04181637 0,14227464 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04181637 0,14206448 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04181637 0,14185495 ! macrophage differentiation GO:0030225 10 6 0,000 0,04181637 0,14164603 ! astrocyte development GO:0014002 14 6 0,000 0,04181637 0,14143773 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04181637 0,14123004 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04181637 0,14102295 ! interaction with symbiont GO:0051702 8 6 0,000 0,04181637 0,14081648 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04181637 0,14061061 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04181637 0,14040533 ! eating behavior GO:0042755 6 6 0,000 0,04181637 0,14020066 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04181637 0,13999659 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04181637 0,1397931 ! response to copper ion GO:0046688 9 6 0,000 0,04181637 0,13959021 ! DNA topological change GO:0006265 8 6 0,000 0,04181637 0,13938791 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04181637 0,13918619 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04181637 0,13898505 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04181637 0,13878449 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04181637 0,13858452 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04181637 0,13838511 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04181637 0,13818629 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04181637 0,13798803 ! gas homeostasis GO:0033483 11 6 0,000 0,04181637 0,13779034 ! hair follicle maturation GO:0048820 7 6 0,000 0,04181637 0,13759321 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04181637 0,13739665 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04181637 0,13720065 ! Schwann cell development GO:0014044 14 6 0,000 0,04181637 0,13700521 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04181637 0,13681032 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04181637 0,13661599 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04181637 0,1364222 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04181637 0,13622897 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04181637 0,13603629 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04181637 0,13584414 ! histone ubiquitination GO:0016574 7 6 0,000 0,04181637 0,13565255 ! regulation of meiosis GO:0040020 10 6 0,000 0,04181637 0,13546149 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04181637 0,13527096 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04181637 0,13508098 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04181637 0,13489152 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04181637 0,1347026 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04181637 0,1345142 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04181637 0,13432633 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04181637 0,13413899 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04181637 0,13395216 ! receptor internalization GO:0031623 9 6 0,000 0,04181637 0,13376586 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04181637 0,13358008 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04181637 0,13339481 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04181637 0,13321005 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04181637 0,1330258 ! protein deubiquitination GO:0016579 8 6 0,000 0,04181637 0,13284206 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04181637 0,13265883 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04181637 0,13247611 ! axonal fasciculation GO:0007413 9 6 0,000 0,04181637 0,13229389 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04181637 0,13211216 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04181637 0,13193094 ! midbrain development GO:0030901 6 6 0,000 0,04181637 0,13175021 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04181637 0,13156998 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04181637 0,13139024 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04181637 0,13121099 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04181637 0,13103223 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04181637 0,13085395 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04181637 0,13067616 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04181637 0,13049885 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04181637 0,13032203 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04181637 0,13014568 ! adult feeding behavior GO:0008343 6 6 0,000 0,04181637 0,1299698 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04181637 0,12979441 ! pigment granule transport GO:0051904 12 6 0,000 0,04181637 0,12961948 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04181637 0,12944503 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04181637 0,12927104 ! catecholamine transport GO:0051937 7 6 0,000 0,04181637 0,12909752 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04181637 0,12892447 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04181637 0,12875188 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04181637 0,12857975 ! protein prenylation GO:0018342 10 6 0,000 0,04181637 0,12840808 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04181637 0,12823687 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04181637 0,12806612 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04181637 0,12789582 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04181637 0,12772597 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04181637 0,12755657 ! unsaturated fatty acid metabolic process GO:0033559 66 46 1,000 0,04217421 0,12847774 ! regulation of ossification GO:0030278 71 46 1,000 0,04217421 0,12830779 ! covalent chromatin modification GO:0016569 75 47 1,000 0,04384868 0,13322583 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,04554757 0,13820503 ! heart morphogenesis GO:0003007 65 48 1,000 0,04554757 0,13802294 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,04554757 0,13784133 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,04727047 0,14286738 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,04727047 0,14267989 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,04727047 0,14249289 ! maintenance of location GO:0051235 84 49 1,000 0,04727047 0,14230638 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04861511 0,14616308 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04861511 0,14597227 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04861511 0,14578195 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04861511 0,14559213 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04861511 0,1454028 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04861511 0,14521397 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04861511 0,14502562 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04861511 0,14483777 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,04861511 0,14465039 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04861511 0,14446351 ! reproductive behavior GO:0019098 12 7 0,000 0,04861511 0,1442771 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04861511 0,14409118 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04861511 0,14390573 ! oligopeptide transport GO:0006857 11 7 0,000 0,04861511 0,14372076 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04861511 0,14353627 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04861511 0,14335225 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04861511 0,1431687 ! RNA methylation GO:0001510 11 7 0,000 0,04861511 0,14298562 ! pericardium development GO:0060039 8 7 0,000 0,04861511 0,14280301 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04861511 0,14262086 ! fibril organization GO:0043206 13 7 0,000 0,04861511 0,14243918 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,04861511 0,14225796 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04861511 0,1420772 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04861511 0,1418969 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04861511 0,14171705 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04861511 0,14153766 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04861511 0,14135873 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04861511 0,14118025 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04861511 0,14100221 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04861511 0,14082463 ! chemosensory behavior GO:0007635 9 7 0,000 0,04861511 0,14064749 ! microtubule bundle formation GO:0001578 8 7 0,000 0,04861511 0,1404708 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,04861511 0,14029455 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04861511 0,14011874 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04861511 0,13994337 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04861511 0,13976844 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04861511 0,13959395 ! reflex GO:0060004 12 7 0,000 0,04861511 0,13941989 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04861511 0,13924627 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04861511 0,13907308 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04861511 0,13890032 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04861511 0,13872798 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,04861511 0,13855608 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04861511 0,1383846 ! spinal cord patterning GO:0021511 7 7 0,000 0,04861511 0,13821354 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04861511 0,13804291 ! adrenal gland development GO:0030325 17 7 0,000 0,04861511 0,13787269 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04861511 0,1377029 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04861511 0,13753352 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04861511 0,13736456 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04861511 0,13719602 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04861511 0,13702789 ! endosome organization GO:0007032 10 7 0,000 0,04861511 0,13686017 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04861511 0,13669285 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04861511 0,13652595 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04861511 0,13635946 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,04861511 0,13619337 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04861511 0,13602768 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04861511 0,1358624 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04861511 0,13569752 ! galactose metabolic process GO:0006012 10 7 0,000 0,04861511 0,13553304 ! vesicle fusion GO:0006906 15 7 0,000 0,04861511 0,13536895 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04861511 0,13520527 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04861511 0,13504197 ! organ growth GO:0035265 11 7 0,000 0,04861511 0,13487908 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04861511 0,13471657 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,04861511 0,13455446 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04861511 0,13439273 ! retinol metabolic process GO:0042572 9 7 0,000 0,04861511 0,1342314 ! behavioral fear response GO:0001662 13 7 0,000 0,04861511 0,13407045 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04861511 0,13390989 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04861511 0,13374971 ! rRNA modification GO:0000154 12 7 0,000 0,04861511 0,13358991 ! protein heterooligomerization GO:0051291 10 7 0,000 0,04861511 0,1334305 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04861511 0,13327146 ! response to UV-B GO:0010224 11 7 0,000 0,04861511 0,1331128 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,04861511 0,13295452 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04861511 0,13279662 ! intermediate filament organization GO:0045109 11 7 0,000 0,04861511 0,13263909 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04861511 0,13248194 ! fibrinolysis GO:0042730 9 7 0,000 0,04861511 0,13232515 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04861511 0,13216874 ! B cell lineage commitment GO:0002326 17 7 0,000 0,04861511 0,1320127 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04861511 0,13185702 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04861511 0,13170171 ! response to tropane GO:0014073 13 7 0,000 0,04861511 0,13154677 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04861511 0,13139219 ! melanosome localization GO:0032400 10 7 0,000 0,04861511 0,13123798 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04861511 0,13108412 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04861511 0,13093063 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04861511 0,13077749 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04861511 0,13062471 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04861511 0,13047229 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04861511 0,13032023 ! mast cell activation GO:0045576 9 7 0,000 0,04861511 0,13016852 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04861511 0,13001716 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,04861511 0,12986615 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04861511 0,12971549 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04861511 0,12956519 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04861511 0,12941523 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04861511 0,12926561 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04861511 0,12911635 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04861511 0,12896742 ! T cell lineage commitment GO:0002360 12 7 0,000 0,04861511 0,12881884 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04861511 0,1286706 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04861511 0,12852271 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04861511 0,12837515 ! response to tumor cell GO:0002347 12 7 0,000 0,04861511 0,12822793 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04861511 0,12808105 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04861511 0,1279345 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04861511 0,12778829 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,04861511 0,12764241 ! diuresis GO:0030146 12 7 0,000 0,04861511 0,12749687 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04861511 0,12735166 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,04861511 0,12720677 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04861511 0,12706222 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04861511 0,126918 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04861511 0,1267741 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04861511 0,12663053 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04861511 0,12648728 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04861511 0,12634436 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04861511 0,12620176 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,04861511 0,12605948 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,04861511 0,12591752 ! lymph node development GO:0048535 9 7 0,000 0,04861511 0,12577588 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04861511 0,12563456 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04861511 0,12549355 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04861511 0,12535286 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04861511 0,12521249 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04861511 0,12507243 ! ATP catabolic process GO:0006200 10 7 0,000 0,04861511 0,12493269 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04861511 0,12479325 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04861511 0,12465413 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04861511 0,12451532 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04861511 0,12437681 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04861511 0,12423862 ! muscle adaptation GO:0043500 12 7 0,000 0,04861511 0,12410073 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04861511 0,12396314 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04861511 0,12382586 ! retina homeostasis GO:0001895 9 7 0,000 0,04861511 0,12368889 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04861511 0,12355222 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04861511 0,12341584 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04861511 0,12327977 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04861511 0,123144 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04861511 0,12300853 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04861511 0,12287336 ! regulation of actin filament length GO:0030832 72 50 1,000 0,04901695 0,123753 ! ear development GO:0043583 72 50 1,000 0,04901695 0,12361731 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,04901695 0,12348191 ! membrane fusion GO:0006944 80 50 1,000 0,04901695 0,12334681 ! muscle fiber development GO:0048747 74 51 1,000 0,0507866 0,12766032 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,0507866 0,12752095 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,0507866 0,12738189 ! regulation of cellular component size GO:0032535 74 52 1,000 0,05257902 0,13173392 ! aging GO:0007568 79 52 1,000 0,05257902 0,13159058 ! establishment of organelle localization GO:0051656 85 52 1,000 0,05257902 0,13144754 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,05439378 0,13583681 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,05439378 0,13568948 ! single fertilization GO:0007338 59 53 1,000 0,05439378 0,13554247 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,055366 0,13781579 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,055366 0,1376668 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,055366 0,13751813 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,055366 0,13736979 ! associative learning GO:0008306 15 8 0,000 0,055366 0,13722176 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,055366 0,13707405 ! phosphate transport GO:0006817 10 8 0,000 0,055366 0,13692666 ! N-glycan processing GO:0006491 12 8 0,000 0,055366 0,13677958 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,055366 0,13663282 ! UTP metabolic process GO:0046051 8 8 0,000 0,055366 0,13648638 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,055366 0,13634025 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,055366 0,13619443 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,055366 0,13604892 ! succinate metabolic process GO:0006105 14 8 0,000 0,055366 0,13590373 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,055366 0,13575884 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,055366 0,13561426 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,055366 0,13546999 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,055366 0,13532603 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,055366 0,13518237 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,055366 0,13503902 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,055366 0,13489597 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,055366 0,13475322 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,055366 0,13461077 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,055366 0,13446863 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,055366 0,13432678 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,055366 0,13418524 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,055366 0,13404399 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,055366 0,13390304 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,055366 0,13376239 ! astrocyte differentiation GO:0048708 16 8 0,000 0,055366 0,13362203 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,055366 0,13348196 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,055366 0,13334219 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,055366 0,13320271 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,055366 0,13306352 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,055366 0,13292463 ! melanin metabolic process GO:0006582 12 8 0,000 0,055366 0,13278602 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,055366 0,1326477 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,055366 0,13250967 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,055366 0,13237193 ! macrophage activation GO:0042116 12 8 0,000 0,055366 0,13223447 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,055366 0,13209729 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,055366 0,13196041 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,055366 0,1318238 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,055366 0,13168748 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,055366 0,13155144 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,055366 0,13141568 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,055366 0,1312802 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,055366 0,131145 ! ruffle organization GO:0031529 11 8 0,000 0,055366 0,13101007 ! osteoblast development GO:0002076 13 8 0,000 0,055366 0,13087543 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,055366 0,13074106 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,055366 0,13060697 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,055366 0,13047315 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,055366 0,1303396 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,055366 0,13020633 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,055366 0,13007333 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,055366 0,1299406 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,055366 0,12980815 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,055366 0,12967596 ! brain morphogenesis GO:0048854 20 8 0,000 0,055366 0,12954404 ! oligodendrocyte development GO:0014003 8 8 0,000 0,055366 0,12941239 ! segment specification GO:0007379 10 8 0,000 0,055366 0,12928101 ! cellular extravasation GO:0045123 11 8 0,000 0,055366 0,12914989 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,055366 0,12901904 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,055366 0,12888845 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,055366 0,12875813 ! snRNA metabolic process GO:0016073 10 8 0,000 0,055366 0,12862807 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,055366 0,12849828 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,055366 0,12836874 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,055366 0,12823947 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,055366 0,12811045 ! nucleosome disassembly GO:0006337 12 8 0,000 0,055366 0,1279817 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,055366 0,1278532 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,055366 0,12772497 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,055366 0,12759699 ! icosanoid secretion GO:0032309 12 8 0,000 0,055366 0,12746926 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,055366 0,12734179 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,055366 0,12721458 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,055366 0,12708762 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,055366 0,12696091 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,055366 0,12683445 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,055366 0,12670825 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,055366 0,1265823 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,055366 0,1264566 ! sterol catabolic process GO:0016127 9 8 0,000 0,055366 0,12633114 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,055366 0,12620594 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,055366 0,12608098 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,055366 0,12595627 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,055366 0,12583181 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,055366 0,12570759 ! prophase GO:0051324 11 8 0,000 0,055366 0,12558362 ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,055366 0,12545989 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,055366 0,12533641 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,055366 0,12521317 ! hormone catabolic process GO:0042447 13 8 0,000 0,055366 0,12509017 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,055366 0,12496741 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,055366 0,12484489 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,055366 0,12472262 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,055366 0,12460058 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,055366 0,12447878 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,055366 0,12435722 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,055366 0,12423589 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,055366 0,12411481 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,055366 0,12399396 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,055366 0,12387334 ! lamellipodium assembly GO:0030032 9 8 0,000 0,055366 0,12375296 ! regulation of embryonic development GO:0045995 16 8 0,000 0,055366 0,12363281 ! mitochondrion localization GO:0051646 12 8 0,000 0,055366 0,12351289 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,055366 0,12339321 ! regulation of mitosis GO:0007088 84 54 1,000 0,0562305 0,1251986 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 66 54 1,000 0,0562305 0,12507752 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,0562305 0,12495667 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,0562305 0,12483606 ! mesoderm development GO:0007498 76 55 1,000 0,05808877 0,12883721 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,05996821 0,13287754 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,05996821 0,13274965 ! carbohydrate transport GO:0008643 74 57 1,000 0,06186842 0,13682439 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,06186842 0,13669296 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,06206936 0,13700531 ! regulation of developmental growth GO:0048638 13 9 0,000 0,06206936 0,13687395 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,06206936 0,13674285 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06206936 0,13661199 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06206936 0,13648139 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06206936 0,13635104 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06206936 0,13622093 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,06206936 0,13609107 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06206936 0,13596146 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06206936 0,1358321 ! GTP metabolic process GO:0046039 9 9 0,000 0,06206936 0,13570298 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06206936 0,13557411 ! social behavior GO:0035176 14 9 0,000 0,06206936 0,13544548 ! artery development GO:0060840 19 9 0,000 0,06206936 0,13531709 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,06206936 0,13518895 ! regulation of glycolysis GO:0006110 15 9 0,000 0,06206936 0,13506105 ! response to pain GO:0048265 16 9 0,000 0,06206936 0,1349334 ! protein complex disassembly GO:0043241 17 9 0,000 0,06206936 0,13480598 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06206936 0,13467881 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06206936 0,13455187 ! lung alveolus development GO:0048286 17 9 0,000 0,06206936 0,13442517 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06206936 0,13429871 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06206936 0,13417249 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06206936 0,13404651 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06206936 0,13392076 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06206936 0,13379525 ! protein targeting to ER GO:0045047 19 9 0,000 0,06206936 0,13366998 ! T cell selection GO:0045058 18 9 0,000 0,06206936 0,13354493 ! endoderm development GO:0007492 12 9 0,000 0,06206936 0,13342012 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06206936 0,13329555 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06206936 0,13317121 ! arginine catabolic process GO:0006527 10 9 0,000 0,06206936 0,1330471 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,06206936 0,13292322 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06206936 0,13279957 GO:0010833|telomere maintenance via telomere lengthening, ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06206936 0,13267615 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,06206936 0,13255296 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06206936 0,13242999 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06206936 0,13230726 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06206936 0,13218475 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06206936 0,13206247 ! mannose metabolic process GO:0006013 9 9 0,000 0,06206936 0,13194042 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06206936 0,13181859 ! receptor clustering GO:0043113 15 9 0,000 0,06206936 0,13169699 ! epithelial cell development GO:0002064 10 9 0,000 0,06206936 0,13157561 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06206936 0,13145445 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06206936 0,13133352 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06206936 0,13121281 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06206936 0,13109232 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06206936 0,13097205 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,06206936 0,130852 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,06206936 0,13073217 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,06206936 0,13061257 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06206936 0,13049318 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06206936 0,130374 ! DNA ligation GO:0006266 14 9 0,000 0,06206936 0,13025505 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06206936 0,13013631 ! response to amine stimulus GO:0014075 13 9 0,000 0,06206936 0,13001779 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06206936 0,12989948 ! renal water homeostasis GO:0003091 14 9 0,000 0,06206936 0,12978139 ! postreplication repair GO:0006301 11 9 0,000 0,06206936 0,12966352 ! mRNA cleavage GO:0006379 13 9 0,000 0,06206936 0,12954586 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06206936 0,12942841 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,06206936 0,12931117 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06206936 0,12919415 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06206936 0,12907734 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06206936 0,12896074 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06206936 0,12884434 ! acid secretion GO:0046717 14 9 0,000 0,06206936 0,12872816 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06206936 0,12861219 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06206936 0,12849643 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06206936 0,12838088 ! purine base metabolic process GO:0006144 18 9 0,000 0,06206936 0,12826553 ! oocyte differentiation GO:0009994 12 9 0,000 0,06206936 0,12815039 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,06206936 0,12803546 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06206936 0,12792073 ! spleen development GO:0048536 15 9 0,000 0,06206936 0,12780621 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06206936 0,12769189 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06206936 0,12757778 ! detection of calcium ion GO:0005513 13 9 0,000 0,06206936 0,12746387 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06206936 0,12735016 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06206936 0,12723666 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06206936 0,12712336 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06206936 0,12701026 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06206936 0,12689736 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06206936 0,12678467 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,06206936 0,12667217 ! prepulse inhibition GO:0060134 14 9 0,000 0,06206936 0,12655987 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06206936 0,12644777 ! insulin secretion GO:0030073 17 9 0,000 0,06206936 0,12633587 ! sequestering of metal ion GO:0051238 11 9 0,000 0,06206936 0,12622417 ! response to nicotine GO:0035094 16 9 0,000 0,06206936 0,12611266 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06206936 0,12600135 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06206936 0,12589024 ! localization within membrane GO:0051668 15 9 0,000 0,06206936 0,12577932 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,06378902 0,12915031 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,06768988 0,13692764 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,06768988 0,13680732 GO:0035113|embryonic appendage morphogenesis, ! fertilization GO:0009566 68 60 1,000 0,06768988 0,13668721 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,06768988 0,1365673 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,06872554 0,13853527 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,06872554 0,13841396 ! neuron fate specification GO:0048665 11 10 0,000 0,06872554 0,13829286 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,06872554 0,13817198 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,06872554 0,1380513 ! thyroid gland development GO:0030878 19 10 0,000 0,06872554 0,13793084 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,06872554 0,13781059 ! synapsis GO:0007129 13 10 0,000 0,06872554 0,13769054 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,06872554 0,13757071 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,06872554 0,13745108 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,06872554 0,13733166 ! sulfate transport GO:0008272 12 10 0,000 0,06872554 0,13721245 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,06872554 0,13709345 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,06872554 0,13697465 ! androgen metabolic process GO:0008209 13 10 0,000 0,06872554 0,13685605 ! phospholipid efflux GO:0033700 16 10 0,000 0,06872554 0,13673767 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,06872554 0,13661948 ! blood vessel remodeling GO:0001974 21 10 0,000 0,06872554 0,13650151 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,06872554 0,13638373 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,06872554 0,13626616 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,06872554 0,13614879 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,06872554 0,13603162 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06872554 0,13591465 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,06872554 0,13579789 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,06872554 0,13568132 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,06872554 0,13556496 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,06872554 0,13544879 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,06872554 0,13533283 ! melanocyte differentiation GO:0030318 15 10 0,000 0,06872554 0,13521706 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,06872554 0,13510149 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,06872554 0,13498612 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06872554 0,13487094 ! response to X-ray GO:0010165 16 10 0,000 0,06872554 0,13475596 ! B cell proliferation GO:0042100 14 10 0,000 0,06872554 0,13464118 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,06872554 0,13452659 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,06872554 0,1344122 ! forebrain cell migration GO:0021885 17 10 0,000 0,06872554 0,134298 ! lipid digestion GO:0044241 15 10 0,000 0,06872554 0,13418399 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,06872554 0,13407018 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,06872554 0,13395656 ! UV protection GO:0009650 14 10 0,000 0,06872554 0,13384314 ! entry into host cell GO:0030260 20 10 0,000 0,06872554 0,1337299 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,06872554 0,13361686 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,06872554 0,13350401 ! negative regulation of ossification GO:0030279 19 10 0,000 0,06872554 0,13339134 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,06872554 0,13327887 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,06872554 0,13316659 ! regulation of bone resorption GO:0045124 24 10 0,000 0,06872554 0,1330545 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,06872554 0,13294259 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,06872554 0,13283088 ! regulation of organ growth GO:0046620 11 10 0,000 0,06872554 0,13271935 ! response to dsRNA GO:0043331 18 10 0,000 0,06872554 0,13260801 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,06872554 0,13249685 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06872554 0,13238588 ! embryonic axis specification GO:0000578 12 10 0,000 0,06872554 0,1322751 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,06872554 0,1321645 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,06872554 0,13205409 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,06872554 0,13194386 ! cranial nerve development GO:0021545 12 10 0,000 0,06872554 0,13183381 ! fucose catabolic process GO:0019317 16 10 0,000 0,06872554 0,13172395 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,06872554 0,13161427 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,06872554 0,13150478 ! protein sumoylation GO:0016925 12 10 0,000 0,06872554 0,13139546 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,06872554 0,13128633 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06872554 0,13117738 ! zymogen activation GO:0031638 14 10 0,000 0,06872554 0,13106861 ! salivary gland development GO:0007431 22 10 0,000 0,06872554 0,13096002 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06872554 0,13085161 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,06872554 0,13074338 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,06872554 0,13063532 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,06872554 0,13052745 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,06872554 0,13041976 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,06872554 0,13031224 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06872554 0,1302049 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,06872554 0,13009773 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,06872554 0,12999074 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,06872554 0,12988393 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,06872554 0,12977729 ! detection of bacterium GO:0016045 10 10 0,000 0,06872554 0,12967083 ! embryonic gut development GO:0048566 11 10 0,000 0,06872554 0,12956454 ! activation of innate immune response GO:0002218 10 10 0,000 0,06872554 0,12945843 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,06872554 0,12935249 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,06872554 0,12924672 ! developmental induction GO:0031128 13 10 0,000 0,06872554 0,12914113 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,06872554 0,12903571 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,06872554 0,12893046 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,06872554 0,12882538 ! meiosis GO:0007126 96 61 1,000 0,06966939 0,13048828 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,06966939 0,1303821 ! lipoprotein metabolic process GO:0042157 89 61 1,000 0,06966939 0,1302761 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,06966939 0,13017027 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,06966939 0,13006462 ! amine catabolic process GO:0009310 90 62 1,000 0,0716678 0,1336869 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,0716678 0,13357857 ! meiotic cell cycle GO:0051321 97 62 1,000 0,0716678 0,13347041 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,07368475 0,13711564 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,07368475 0,13700479 ! rRNA transcription GO:0009303 17 11 0,000 0,07533486 0,13995976 ! respiratory burst GO:0045730 14 11 0,000 0,07533486 0,13984679 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07533486 0,13973401 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07533486 0,13962142 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07533486 0,139509 ! virus-host interaction GO:0019048 17 11 0,000 0,07533486 0,13939676 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,07533486 0,13928471 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07533486 0,13917283 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07533486 0,13906114 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07533486 0,13894962 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07533486 0,13883828 ! mating GO:0007618 14 11 0,000 0,07533486 0,13872712 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,07533486 0,13861614 ! T cell proliferation GO:0042098 20 11 0,000 0,07533486 0,13850534 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,07533486 0,13839471 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,07533486 0,13828426 ! bone resorption GO:0045453 16 11 0,000 0,07533486 0,13817399 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07533486 0,13806389 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07533486 0,13795396 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07533486 0,13784422 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07533486 0,13773464 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07533486 0,13762524 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07533486 0,13751601 ! syncytium formation GO:0006949 15 11 0,000 0,07533486 0,13740696 ! plasma membrane organization GO:0007009 18 11 0,000 0,07533486 0,13729808 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07533486 0,13718937 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07533486 0,13708084 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07533486 0,13697247 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,07533486 0,13686428 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07533486 0,13675626 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07533486 0,13664841 ! adult heart development GO:0007512 11 11 0,000 0,07533486 0,13654072 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,07533486 0,13643321 ! temperature homeostasis GO:0001659 16 11 0,000 0,07533486 0,13632587 ! L-glutamate transport GO:0015813 16 11 0,000 0,07533486 0,13621869 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07533486 0,13611169 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07533486 0,13600485 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07533486 0,13589818 ! stem cell development GO:0048864 29 11 0,000 0,07533486 0,13579168 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07533486 0,13568534 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07533486 0,13557917 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07533486 0,13547317 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07533486 0,13536733 ! vasoconstriction GO:0042310 15 11 0,000 0,07533486 0,13526165 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07533486 0,13515615 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07533486 0,1350508 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07533486 0,13494562 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07533486 0,13484061 ! ribosome assembly GO:0042255 13 11 0,000 0,07533486 0,13473575 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07533486 0,13463106 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07533486 0,13452654 ! nucleosome positioning GO:0016584 13 11 0,000 0,07533486 0,13442217 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07533486 0,13431797 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,07533486 0,13421393 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07533486 0,13411005 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07533486 0,13400633 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07533486 0,13390277 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07533486 0,13379937 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07533486 0,13369613 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07533486 0,13359304 ! male genitalia development GO:0030539 13 11 0,000 0,07533486 0,13349012 ! cholesterol efflux GO:0033344 19 11 0,000 0,07533486 0,13338736 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,07533486 0,13328475 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07533486 0,1331823 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07533486 0,13308001 ! germ cell migration GO:0008354 18 11 0,000 0,07533486 0,13297788 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07533486 0,1328759 ! defense response to fungus GO:0050832 12 11 0,000 0,07533486 0,13277408 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07533486 0,13267242 ! lysogeny GO:0030069 18 11 0,000 0,07533486 0,13257091 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07533486 0,13246956 ! acrosome reaction GO:0007340 13 11 0,000 0,07533486 0,13236836 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07533486 0,13226731 ! appendage morphogenesis GO:0035107 93 64 1,000 0,07571988 0,13284189 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,07571988 0,13274063 ! appendage development GO:0048736 94 65 1,000 0,07777282 0,13623571 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,07777282 0,13613203 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,07777282 0,13602851 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,07984324 0,13954366 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,07984324 0,1394377 ! axon guidance GO:0007411 99 66 1,000 0,07984324 0,13933191 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,07984324 0,13922627 ! lactation GO:0007595 20 12 0,000 0,08189765 0,14270045 ! reproductive cellular process GO:0048610 14 12 0,000 0,08189765 0,14259242 ! tRNA modification GO:0006400 14 12 0,000 0,08189765 0,14248456 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08189765 0,14237686 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08189765 0,14226933 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,08189765 0,14216196 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08189765 0,14205475 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08189765 0,1419477 ! non-recombinational repair GO:0000726 19 12 0,000 0,08189765 0,14184081 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08189765 0,14173408 ! peroxisomal transport GO:0043574 21 12 0,000 0,08189765 0,14162751 ! cartilage condensation GO:0001502 18 12 0,000 0,08189765 0,14152111 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08189765 0,14141486 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08189765 0,14130877 ! heart looping GO:0001947 15 12 0,000 0,08189765 0,14120284 ! palate development GO:0060021 15 12 0,000 0,08189765 0,14109707 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,08189765 0,14099146 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08189765 0,14088601 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,08189765 0,14078071 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08189765 0,14067557 ! arginine metabolic process GO:0006525 13 12 0,000 0,08189765 0,14057059 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,08189765 0,14046577 ! methionine metabolic process GO:0006555 13 12 0,000 0,08189765 0,1403611 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08189765 0,14025658 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08189765 0,14015223 ! monoamine transport GO:0015844 13 12 0,000 0,08189765 0,14004802 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08189765 0,13994398 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,08189765 0,13984008 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08189765 0,13973634 ! L-amino acid transport GO:0015807 20 12 0,000 0,08189765 0,13963276 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08189765 0,13952933 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08189765 0,13942605 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08189765 0,13932292 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08189765 0,13921995 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08189765 0,13911713 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08189765 0,13901446 ! cerebellum development GO:0021549 13 12 0,000 0,08189765 0,13891194 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08189765 0,13880957 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08189765 0,13870736 ! histone acetylation GO:0016573 23 12 0,000 0,08189765 0,13860529 ! histone methylation GO:0016571 15 12 0,000 0,08189765 0,13850338 ! autonomic nervous system development GO:0048483 23 12 0,000 0,08189765 0,13840161 ! gland morphogenesis GO:0022612 23 12 0,000 0,08189765 0,13829999 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08189765 0,13819853 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,08189765 0,13809721 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08189765 0,13799604 ! response to gamma radiation GO:0010332 20 12 0,000 0,08189765 0,13789502 ! regulation of epidermis development GO:0045682 17 12 0,000 0,08189765 0,13779414 ! intestinal absorption GO:0050892 19 12 0,000 0,08189765 0,13769342 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08189765 0,13759284 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08189765 0,1374924 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,08189765 0,13739212 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08189765 0,13729198 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,08189765 0,13719198 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08189765 0,13709213 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08189765 0,13699243 ! microspike assembly GO:0030035 23 12 0,000 0,08189765 0,13689287 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08189765 0,13679346 ! response to cold GO:0009409 14 12 0,000 0,08189765 0,13669419 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,08193079 0,13665033 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,08615589 0,14359315 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,08829277 0,14704806 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,08841423 0,1471438 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,08841423 0,1470374 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,08841423 0,14693116 ! cGMP metabolic process GO:0046068 16 13 0,000 0,08841423 0,14682508 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,08841423 0,14671914 ! water transport GO:0006833 17 13 0,000 0,08841423 0,14661336 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,08841423 0,14650773 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,08841423 0,14640225 ! lipid localization GO:0010876 24 13 0,000 0,08841423 0,14629693 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,08841423 0,14619175 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,08841423 0,14608673 ! organelle fusion GO:0048284 28 13 0,000 0,08841423 0,14598186 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,08841423 0,14587714 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,08841423 0,14577257 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,08841423 0,14566815 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,08841423 0,14556387 ! response to hexose stimulus GO:0009746 19 13 0,000 0,08841423 0,14545975 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glutamate metabolic process GO:0006536 18 13 0,000 0,08841423 0,14535578 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,08841423 0,14525195 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,08841423 0,14514827 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,08841423 0,14504474 ! NAD metabolic process GO:0019674 21 13 0,000 0,08841423 0,14494136 ! exocrine system development GO:0035272 27 13 0,000 0,08841423 0,14483813 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,08841423 0,14473504 ! bone mineralization GO:0030282 15 13 0,000 0,08841423 0,1446321 ! regulation of exocytosis GO:0017157 17 13 0,000 0,08841423 0,1445293 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,08841423 0,14442666 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,08841423 0,14432415 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,08841423 0,1442218 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,08841423 0,14411958 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,08841423 0,14401751 ! genitalia development GO:0048806 15 13 0,000 0,08841423 0,14391559 ! regulation of cellular pH GO:0030641 20 13 0,000 0,08841423 0,14381381 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,08841423 0,14371218 ! cellular pigmentation GO:0033059 24 13 0,000 0,08841423 0,14361069 ! tissue regeneration GO:0042246 21 13 0,000 0,08841423 0,14350934 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,08841423 0,14340813 ! cofactor transport GO:0051181 19 13 0,000 0,08841423 0,14330707 ! NADP metabolic process GO:0006739 18 13 0,000 0,08841423 0,14320615 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,08841423 0,14310537 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,08841423 0,14300473 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08841423 0,14290424 ! gas transport GO:0015669 18 13 0,000 0,08841423 0,14280388 ! regulation of RNA stability GO:0043487 28 13 0,000 0,08841423 0,14270367 ! heme biosynthetic process GO:0006783 20 13 0,000 0,08841423 0,1426036 ! regulation of axon extension GO:0030516 23 13 0,000 0,08841423 0,14250367 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,08841423 0,14240387 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,08841423 0,14230422 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,08841423 0,14220471 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,08841423 0,14210533 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,08841423 0,1420061 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,09044544 0,14516714 ! response to hypoxia GO:0001666 132 72 1,000 0,09261355 0,14854336 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,09261355 0,14843984 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,09261355 0,14833647 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,0947968 0,15172766 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,09488493 0,1517631 ! superoxide anion generation GO:0042554 18 14 0,000 0,09488493 0,15165764 ! neuron maturation GO:0042551 21 14 0,000 0,09488493 0,15155232 ! regulation of S phase GO:0033261 18 14 0,000 0,09488493 0,15144715 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09488493 0,15134212 ! myotube differentiation GO:0014902 21 14 0,000 0,09488493 0,15123724 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,09488493 0,15113251 ! inositol metabolic process GO:0006020 20 14 0,000 0,09488493 0,15102792 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09488493 0,15092347 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09488493 0,15081917 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09488493 0,15071501 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09488493 0,150611 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09488493 0,15050713 ! response to cAMP GO:0051591 19 14 0,000 0,09488493 0,1504034 ! startle response GO:0001964 21 14 0,000 0,09488493 0,15029982 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09488493 0,15019638 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09488493 0,15009308 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09488493 0,14998992 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09488493 0,14988691 ! glycine metabolic process GO:0006544 22 14 0,000 0,09488493 0,14978403 ! pituitary gland development GO:0021983 23 14 0,000 0,09488493 0,1496813 ! cellular response to starvation GO:0009267 21 14 0,000 0,09488493 0,14957871 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,09488493 0,14947626 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,09488493 0,14937395 ! regulation of heart rate GO:0002027 23 14 0,000 0,09488493 0,14927178 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09488493 0,14916975 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09488493 0,14906785 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,09488493 0,1489661 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,09488493 0,14886449 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,09488493 0,14876301 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09488493 0,14866167 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09488493 0,14856048 ! axon cargo transport GO:0008088 27 14 0,000 0,09488493 0,14845941 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09488493 0,14835849 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09488493 0,1482577 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09488493 0,14815705 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,09488493 0,14805654 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09488493 0,14795616 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09488493 0,14785592 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09488493 0,14775581 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09488493 0,14765584 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09488493 0,14755601 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09488493 0,14745631 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09488493 0,14735674 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09488493 0,14725731 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,09488493 0,14715802 ! muscle maintenance GO:0046716 19 14 0,000 0,09488493 0,14705885 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09488493 0,14695982 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09488493 0,14686093 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09488493 0,14676216 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,09488493 0,14666353 ! cell killing GO:0001906 20 14 0,000 0,09488493 0,14656504 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,09488493 0,14646667 ! cilium assembly GO:0042384 20 14 0,000 0,09488493 0,14636844 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09488493 0,14627033 ! response to oxygen levels GO:0070482 137 74 1,000 0,09699486 0,14942276 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,09699486 0,14932274 ! blood coagulation GO:0007596 116 75 1,000 0,09920741 0,15262679 GO:0050817|coagulation, ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,10131007 0,15575745 ! positive regulation of cell size GO:0045793 20 15 0,000 0,10131007 0,15565341 ! metencephalon development GO:0022037 19 15 0,000 0,10131007 0,1555495 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10131007 0,15544573 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,10131007 0,1553421 ! skin development GO:0043588 25 15 0,000 0,10131007 0,15523861 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,10131007 0,15513525 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,10131007 0,15503204 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10131007 0,15492896 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10131007 0,15482601 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,10131007 0,15472321 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,10131007 0,15462054 ! adult walking behavior GO:0007628 25 15 0,000 0,10131007 0,154518 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10131007 0,15441561 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10131007 0,15431334 ! myoblast differentiation GO:0045445 27 15 0,000 0,10131007 0,15421122 ! centrosome cycle GO:0007098 16 15 0,000 0,10131007 0,15410923 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,10131007 0,15400737 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10131007 0,15390565 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,10131007 0,15380406 ! response to osmotic stress GO:0006970 22 15 0,000 0,10131007 0,15370261 ! vesicle coating GO:0006901 25 15 0,000 0,10131007 0,15360129 ! DNA integration GO:0015074 22 15 0,000 0,10131007 0,1535001 ! peptide secretion GO:0002790 27 15 0,000 0,10131007 0,15339905 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,10131007 0,15329812 ! regulation of vasodilation GO:0042312 24 15 0,000 0,10131007 0,15319734 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10131007 0,15309668 ! neuron recognition GO:0008038 22 15 0,000 0,10131007 0,15299616 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10131007 0,15289577 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,10131007 0,15279551 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,10131007 0,15269538 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10131007 0,15259538 ! biomineral formation GO:0031214 18 15 0,000 0,10131007 0,15249552 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10131007 0,15239578 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,10131007 0,15229618 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10131007 0,1521967 ! dopamine metabolic process GO:0042417 30 15 0,000 0,10131007 0,15209736 ! organic cation transport GO:0015695 19 15 0,000 0,10131007 0,15199814 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10131007 0,15189905 GO:0033014|tetrapyrrole biosynthetic process, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,10131007 0,1518001 ! defense response to virus GO:0051607 27 15 0,000 0,10131007 0,15170127 ! peptide hormone processing GO:0016486 19 15 0,000 0,10131007 0,15160257 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,10131007 0,151504 ! amine biosynthetic process GO:0009309 97 76 1,000 0,10143415 0,15159099 ! regulation of protein transport GO:0051223 114 76 1,000 0,10143415 0,15149256 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 1,000 0,10367476 0,15473844 ! gland development GO:0048732 148 77 1,000 0,10367476 0,1546381 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,10367476 0,15453788 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,10367476 0,15443779 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,10592894 0,15769356 ! protein secretion GO:0009306 27 16 0,000 0,10768996 0,16021145 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,10768996 0,16010789 ! hormone secretion GO:0046879 25 16 0,000 0,10768996 0,16000446 ! bone remodeling GO:0046849 24 16 0,000 0,10768996 0,15990116 ! endothelial cell migration GO:0043542 22 16 0,000 0,10768996 0,159798 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,10768996 0,15969497 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,10768996 0,15959207 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10768996 0,15948931 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,10768996 0,15938668 ! glial cell development GO:0021782 24 16 0,000 0,10768996 0,15928418 ! patterning of blood vessels GO:0001569 24 16 0,000 0,10768996 0,15918181 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,10768996 0,15907958 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,10768996 0,15897747 ! protein polyubiquitination GO:0000209 26 16 0,000 0,10768996 0,1588755 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,10768996 0,15877365 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,10768996 0,15867194 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,10768996 0,15857036 ! fructose metabolic process GO:0006000 20 16 0,000 0,10768996 0,15846891 ! regulation of protein binding GO:0043393 27 16 0,000 0,10768996 0,15836758 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,10768996 0,15826639 ! protein export from nucleus GO:0006611 24 16 0,000 0,10768996 0,15816532 ! negative regulation of immune response GO:0050777 28 16 0,000 0,10768996 0,15806439 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,10768996 0,15796358 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,10768996 0,15786291 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,10768996 0,15776236 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,10768996 0,15766193 ! diencephalon development GO:0021536 25 16 0,000 0,10768996 0,15756164 ! oogenesis GO:0048477 23 16 0,000 0,10768996 0,15746147 ! neural crest cell migration GO:0001755 24 16 0,000 0,10768996 0,15736143 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,10768996 0,15726152 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,10768996 0,15716174 ! steroid catabolic process GO:0006706 22 16 0,000 0,10768996 0,15706208 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,10768996 0,15696255 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,10768996 0,15686314 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,10768996 0,15676386 ! sperm-egg recognition GO:0035036 16 16 0,000 0,10768996 0,15666471 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,10768996 0,15656568 ! nerve development GO:0021675 18 16 0,000 0,10768996 0,15646677 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,10768996 0,15636799 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,10768996 0,15626934 ! cellular respiration GO:0045333 107 79 1,000 0,10819638 0,15690522 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,1104768 0,16011131 GO:0010498|proteasomal protein catabolic process, ! hemostasis GO:0007599 125 81 1,000 0,1127699 0,16333172 ! regulation of neurological system process GO:0031644 122 81 1,000 0,1127699 0,16322893 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,1127699 0,16312627 GO:0002696|positive regulation of leukocyte activation, ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,11402492 0,16483803 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,11402492 0,16473449 ! negative regulation of defense response GO:0031348 19 17 0,000 0,11402492 0,16463108 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,11402492 0,1645278 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,11402492 0,16442465 ! glycerol metabolic process GO:0006071 20 17 0,000 0,11402492 0,16432162 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,11402492 0,16421873 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,11402492 0,16411596 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,11402492 0,16401333 ! signal complex assembly GO:0007172 29 17 0,000 0,11402492 0,16391082 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,11402492 0,16380844 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,11402492 0,16370619 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,11402492 0,16360406 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,11402492 0,16350206 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,11402492 0,16340019 ! keratinization GO:0031424 17 17 0,000 0,11402492 0,16329845 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,11402492 0,16319683 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,11402492 0,16309534 ! retinoid metabolic process GO:0001523 22 17 0,000 0,11402492 0,16299398 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,11402492 0,16289274 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,11402492 0,16279163 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,11402492 0,16269064 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,11402492 0,16258978 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,11402492 0,16248904 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,11402492 0,16238843 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,11402492 0,16228794 ! membrane budding GO:0006900 29 17 0,000 0,11402492 0,16218758 ! heme metabolic process GO:0042168 27 17 0,000 0,11402492 0,16208734 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,11402492 0,16198722 ! body fluid secretion GO:0007589 27 17 0,000 0,11402492 0,16188723 ! stem cell differentiation GO:0048863 36 17 0,000 0,11402492 0,16178736 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,11402492 0,16168761 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,11402492 0,16158799 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,11402492 0,16148849 ! sensory perception of pain GO:0019233 23 17 0,000 0,11402492 0,16138911 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,11402492 0,16128986 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,11402492 0,16119073 ! synaptogenesis GO:0007416 24 17 0,000 0,11402492 0,16109171 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,11402492 0,16099282 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,11402492 0,16089406 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,11402492 0,16079541 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,11402492 0,16069688 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,11402492 0,16059848 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,11402492 0,16050019 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,11402492 0,16040203 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,11402492 0,16030398 ! ossification GO:0001503 134 82 1,000 0,11507538 0,16168196 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,11507538 0,16158325 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,12031526 0,16883777 ! positive regulation of translation GO:0045727 28 18 0,000 0,12031526 0,16873482 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,12031526 0,168632 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,12031526 0,1685293 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,12031526 0,16842673 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,12031526 0,16832428 ! cAMP metabolic process GO:0046058 33 18 0,000 0,12031526 0,16822195 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,12031526 0,16811975 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,12031526 0,16801767 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,12031526 0,16791572 ! axis specification GO:0009798 26 18 0,000 0,12031526 0,16781389 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,12031526 0,16771219 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,12031526 0,16761061 ! pancreas development GO:0031016 26 18 0,000 0,12031526 0,16750915 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,12031526 0,16740781 ! glutamine metabolic process GO:0006541 23 18 0,000 0,12031526 0,1673066 ! response to retinoic acid GO:0032526 25 18 0,000 0,12031526 0,1672055 ! central nervous system neuron development GO:0021954 30 18 0,000 0,12031526 0,16710453 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,12031526 0,16700369 ! fucose metabolic process GO:0006004 26 18 0,000 0,12031526 0,16690296 ! response to fungus GO:0009620 19 18 0,000 0,12031526 0,16680236 ! peptide cross-linking GO:0018149 31 18 0,000 0,12031526 0,16670187 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,12031526 0,16660151 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,12031526 0,16650127 ! visual learning GO:0008542 35 18 0,000 0,12031526 0,16640115 ! somitogenesis GO:0001756 24 18 0,000 0,12031526 0,16630115 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,12031526 0,16620127 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,12031526 0,16610151 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,12031526 0,16600187 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,12031526 0,16590234 ! vitamin transport GO:0051180 24 18 0,000 0,12031526 0,16580294 ! hormone transport GO:0009914 27 18 0,000 0,12031526 0,16570366 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,12031526 0,16560449 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,12031526 0,16550545 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,12031526 0,16540652 ! cell-cell recognition GO:0009988 20 18 0,000 0,12031526 0,16530771 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,12031526 0,16520902 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,12031526 0,16511045 ! gut development GO:0048565 26 18 0,000 0,12031526 0,16501199 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,12031526 0,16491365 ! rRNA metabolic process GO:0016072 107 85 1,000 0,12206328 0,16720997 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 1,000 0,12206328 0,16711044 ! regulation of protein localization GO:0032880 132 85 1,000 0,12206328 0,16701103 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,12656131 0,17306243 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,12656131 0,1729596 ! positive regulation of ossification GO:0045778 30 19 0,000 0,12656131 0,17285689 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,12656131 0,17275431 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,12656131 0,17265184 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,12656131 0,1725495 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,12656131 0,17244728 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,12656131 0,17234518 ! regeneration GO:0031099 32 19 0,000 0,12656131 0,1722432 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,12656131 0,17214134 ! sensory perception of taste GO:0050909 23 19 0,000 0,12656131 0,1720396 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,12656131 0,17193799 ! smooth muscle contraction GO:0006939 36 19 0,000 0,12656131 0,17183649 ! peroxisome organization GO:0007031 29 19 0,000 0,12656131 0,17173511 ! digestive system process GO:0022600 30 19 0,000 0,12656131 0,17163385 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,12656131 0,17153271 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,12656131 0,17143169 ! response to vitamin A GO:0033189 26 19 0,000 0,12656131 0,17133079 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,12656131 0,17123001 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,12656131 0,17112934 ! response to starvation GO:0042594 30 19 0,000 0,12656131 0,1710288 ! sex determination GO:0007530 29 19 0,000 0,12656131 0,17092837 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,12656131 0,17082806 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,12656131 0,17072786 ! cytolysis GO:0019835 20 19 0,000 0,12656131 0,17062779 ! renal system process GO:0003014 35 19 0,000 0,12656131 0,17052783 ! vasodilation GO:0042311 33 19 0,000 0,12656131 0,17042799 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,12656131 0,17032827 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,12656131 0,17022866 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,12656131 0,17012917 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,12656131 0,1700298 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,12656131 0,16993054 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,12656131 0,16983139 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,12656131 0,16973237 ! sarcomere organization GO:0045214 23 19 0,000 0,12656131 0,16963346 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,12656131 0,16953466 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,12656131 0,16943598 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,12656131 0,16933741 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,12656131 0,16923896 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,12656131 0,16914062 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,12656131 0,1690424 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,12656131 0,16894429 ! protein stabilization GO:0050821 26 19 0,000 0,12656131 0,16884629 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,12677862 0,16903817 GO:0060538|skeletal muscle organ development, ! establishment of RNA localization GO:0051236 128 88 1,000 0,1291525 0,17210357 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,1291525 0,17200391 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,13153682 0,17507795 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,13276336 0,17660828 ! iron ion transport GO:0006826 37 20 0,000 0,13276336 0,1765062 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,13276336 0,17640423 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,13276336 0,17630238 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,13276336 0,17620065 ! response to vitamin GO:0033273 29 20 0,000 0,13276336 0,17609903 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,13276336 0,17599754 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,13276336 0,17589615 ! spinal cord development GO:0021510 31 20 0,000 0,13276336 0,17579489 ! response to ethanol GO:0045471 37 20 0,000 0,13276336 0,17569374 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,13276336 0,17559271 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,13276336 0,1754918 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,13276336 0,175391 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,13276336 0,17529031 ! chromosome condensation GO:0030261 31 20 0,000 0,13276336 0,17518974 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,13276336 0,17508929 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,13276336 0,17498895 ! DNA modification GO:0006304 28 20 0,000 0,13276336 0,17488873 ! collagen fibril organization GO:0030199 45 20 0,000 0,13276336 0,17478862 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,13276336 0,17468863 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,13276336 0,17458875 ! collagen catabolic process GO:0030574 25 20 0,000 0,13276336 0,17448899 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,13276336 0,17438933 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,13276336 0,1742898 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,13276336 0,17419037 ! alditol metabolic process GO:0019400 24 20 0,000 0,13276336 0,17409106 ! RNA localization GO:0006403 135 91 1,000 0,13633575 0,17867363 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,13874983 0,18173383 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,13892172 0,18185541 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,13892172 0,18175197 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,13892172 0,18164864 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,13892172 0,18154543 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,13892172 0,18144234 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,13892172 0,18133936 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,13892172 0,18123651 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,13892172 0,18113376 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,13892172 0,18103114 ! vesicle docking GO:0048278 27 21 0,000 0,13892172 0,18092863 ! phototransduction GO:0007602 25 21 0,000 0,13892172 0,18082624 ! dendrite development GO:0016358 35 21 0,000 0,13892172 0,18072396 ! visual behavior GO:0007632 39 21 0,000 0,13892172 0,1806218 ! ovarian follicle development GO:0001541 30 21 0,000 0,13892172 0,18051975 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,13892172 0,18041782 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,13892172 0,180316 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,13892172 0,1802143 ! cell aging GO:0007569 32 21 0,000 0,13892172 0,18011272 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,13892172 0,18001125 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,13892172 0,17990989 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,13892172 0,17980864 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,13892172 0,17970751 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,13892172 0,1796065 ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,13892172 0,1795056 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,13892172 0,17940481 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,13892172 0,17930413 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,13892172 0,17920357 ! fatty acid transport GO:0015908 30 21 0,000 0,13892172 0,17910312 ! immunoglobulin production GO:0002377 33 21 0,000 0,13892172 0,17900278 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,13892172 0,17890255 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,13892172 0,17880244 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,13892172 0,17870244 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,13892172 0,17860255 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,13892172 0,17850277 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,13892172 0,1784031 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,13892172 0,17830355 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,13892172 0,17820411 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,13892172 0,17810477 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,13892172 0,17800555 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,13892172 0,17790644 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,13892172 0,17780743 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,14117332 0,18058878 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,1450367 0,18542769 ! viral genome replication GO:0019079 29 22 0,000 0,1450367 0,18532468 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,1450367 0,18522178 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,1450367 0,18511899 ! molting cycle process GO:0022404 40 22 0,000 0,1450367 0,18501632 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,1450367 0,18491376 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,1450367 0,18481131 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,1450367 0,18470898 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,1450367 0,18460676 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,1450367 0,18450466 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,1450367 0,18440266 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,1450367 0,18430078 ! lysosome organization GO:0007040 37 22 0,000 0,1450367 0,18419902 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,1450367 0,18409736 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,1450367 0,18399582 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,1450367 0,18389439 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,1450367 0,18379307 ! membrane depolarization GO:0051899 35 22 0,000 0,1450367 0,18369186 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,1450367 0,18359076 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,1450367 0,18348978 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,1450367 0,18338891 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,1450367 0,18328814 ! neural tube closure GO:0001843 33 22 0,000 0,1450367 0,18318749 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,1450367 0,18308695 ! protein tetramerization GO:0051262 39 22 0,000 0,1450367 0,18298652 ! regulation of binding GO:0051098 151 95 1,000 0,14604751 0,18416078 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,14849772 0,18714781 ! protein maturation GO:0051604 129 96 1,000 0,14849772 0,18704532 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,15110861 0,19022978 ! neuron fate commitment GO:0048663 32 23 0,000 0,15110861 0,19012571 ! embryonic pattern specification GO:0009880 31 23 0,000 0,15110861 0,19002176 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,15110861 0,18991792 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,15110861 0,1898142 ! vesicle targeting GO:0006903 32 23 0,000 0,15110861 0,18971059 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,15110861 0,18960709 ! osteoblast differentiation GO:0001649 40 23 0,000 0,15110861 0,18950371 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,15110861 0,18940044 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,15110861 0,18929728 ! interaction with host GO:0051701 37 23 0,000 0,15110861 0,18919423 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,15110861 0,18909129 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,15110861 0,18898847 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,15110861 0,18888576 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,15110861 0,18878316 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,15110861 0,18868067 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,15110861 0,1885783 ! pentose metabolic process GO:0019321 31 23 0,000 0,15110861 0,18847603 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,15110861 0,18837388 ! spermatid development GO:0007286 33 23 0,000 0,15110861 0,18827183 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,15110861 0,1881699 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,15110861 0,18806807 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,15110861 0,18796636 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,15110861 0,18786476 ! telomere organization GO:0032200 32 23 0,000 0,15110861 0,18776326 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,15110861 0,18766188 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,15110861 0,1875606 ! regulation of amine transport GO:0051952 38 23 0,000 0,15110861 0,18745944 ! liver development GO:0001889 40 23 0,000 0,15110861 0,18735838 ! extracellular structure organization GO:0043062 156 99 1,000 0,15589789 0,19319243 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,15713774 0,19462401 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,15713774 0,19451926 ! initiation of viral infection GO:0019059 42 24 0,000 0,15713774 0,19441463 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,15713774 0,1943101 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,15713774 0,19420569 ! superoxide metabolic process GO:0006801 32 24 0,000 0,15713774 0,19410139 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,15713774 0,1939972 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,15713774 0,19389313 ! fat cell differentiation GO:0045444 37 24 0,000 0,15713774 0,19378916 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,15713774 0,19368531 ! sperm motility GO:0030317 27 24 0,000 0,15713774 0,19358157 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,15713774 0,19347794 ! vacuole organization GO:0007033 39 24 0,000 0,15713774 0,19337442 ! receptor metabolic process GO:0043112 37 24 0,000 0,15713774 0,19327101 ! neural crest cell development GO:0014032 39 24 0,000 0,15713774 0,19316771 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,15713774 0,19306453 ! primary neural tube formation GO:0014020 35 24 0,000 0,15713774 0,19296145 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,15713774 0,19285848 ! base-excision repair GO:0006284 31 24 0,000 0,15713774 0,19275562 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,15713774 0,19265287 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,15713774 0,19255024 ! glutathione metabolic process GO:0006749 29 24 0,000 0,15713774 0,19244771 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,15713774 0,19234529 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,15713774 0,19224297 ! regulation of translation GO:0006417 151 100 1,000 0,15838034 0,19366017 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,15838034 0,19355727 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,15838034 0,19345448 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,16312438 0,19914336 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,16312438 0,19903771 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,16312438 0,19893218 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,16312438 0,19882675 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,16312438 0,19872144 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,16312438 0,19861624 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,16312438 0,19851116 ! peptide transport GO:0015833 43 25 0,000 0,16312438 0,19840618 ! male gonad development GO:0008584 33 25 0,000 0,16312438 0,19830131 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,16312438 0,19819656 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,16312438 0,19809191 ! phospholipid transport GO:0015914 35 25 0,000 0,16312438 0,19798738 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,16312438 0,19788296 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,16312438 0,19777864 ! detection of light stimulus GO:0009583 30 25 0,000 0,16312438 0,19767444 ! leukocyte proliferation GO:0070661 39 25 0,000 0,16312438 0,19757035 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,16906885 0,2046623 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,16906885 0,20455464 ! translational initiation GO:0006413 43 26 0,000 0,16906885 0,20444709 ! regulation of pH GO:0006885 36 26 0,000 0,16906885 0,20433965 ! circadian rhythm GO:0007623 42 26 0,000 0,16906885 0,20423233 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,16906885 0,20412512 ! post-embryonic development GO:0009791 42 26 0,000 0,16906885 0,20401803 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,16906885 0,20391104 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,16906885 0,20380417 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,16906885 0,20369741 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,16906885 0,20359077 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,16906885 0,20348423 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,16906885 0,2033778 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,16906885 0,20327149 ! regulation of coagulation GO:0050818 39 26 0,000 0,16906885 0,20316529 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,17497143 0,21014846 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,17497143 0,21003878 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,17497143 0,20992921 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,17497143 0,20981976 ! membrane docking GO:0022406 39 27 0,000 0,17497143 0,20971042 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,17497143 0,2096012 ! catechol metabolic process GO:0009712 43 27 0,000 0,17497143 0,20949209 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,17497143 0,20938309 ! acute-phase response GO:0006953 42 27 0,000 0,17497143 0,20927421 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,17497143 0,20916544 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,17497143 0,20905678 ! natural killer cell activation GO:0030101 35 27 0,000 0,17497143 0,20894823 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,17497143 0,2088398 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,18083242 0,21572333 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,18083242 0,21561149 ! phenol metabolic process GO:0018958 44 28 0,000 0,18083242 0,21549978 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,18083242 0,21538818 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,18083242 0,21527669 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,18083242 0,21516532 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,18083242 0,21505407 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,18083242 0,21494293 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,18083242 0,21483191 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,18083242 0,214721 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,18083242 0,2146102 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,18083242 0,21449952 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,18083242 0,21438895 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,18083242 0,2142785 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,18083242 0,21416816 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,18083242 0,21405794 ! mesoderm formation GO:0001707 46 28 0,000 0,18083242 0,21394782 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,18083242 0,21383783 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,18083242 0,21372794 ! BMP signaling pathway GO:0030509 40 28 0,000 0,18083242 0,21361817 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,18083242 0,21350851 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,18083242 0,21339896 ! neural tube formation GO:0001841 41 28 0,000 0,18083242 0,21328952 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,18083242 0,2131802 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,18665211 0,2199282 ! regulation of innate immune response GO:0045088 38 29 0,000 0,18665211 0,21981559 ! ovulation cycle process GO:0022602 41 29 0,000 0,18665211 0,21970309 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,18665211 0,21959071 ! protein targeting to membrane GO:0006612 53 29 0,000 0,18665211 0,21947845 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,18665211 0,2193663 ! mismatch repair GO:0006298 34 29 0,000 0,18665211 0,21925426 ! formation of primary germ layer GO:0001704 48 29 0,000 0,18665211 0,21914234 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,18665211 0,21903053 ! eye morphogenesis GO:0048592 51 29 0,000 0,18665211 0,21891884 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,18665211 0,21880726 ! tissue homeostasis GO:0001894 42 29 0,000 0,18665211 0,2186958 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,19243078 0,22535173 ! collagen metabolic process GO:0032963 40 30 0,000 0,19243078 0,22523704 ! organic anion transport GO:0015711 51 30 0,000 0,19243078 0,22512248 ! cholesterol transport GO:0030301 46 30 0,000 0,19243078 0,22500803 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,19243078 0,22489369 ! spliceosome assembly GO:0000245 49 30 0,000 0,19243078 0,22477948 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,19243078 0,22466537 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,19243078 0,22455139 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,19243078 0,22443752 ! ceramide metabolic process GO:0006672 43 30 0,000 0,19243078 0,22432377 ! ovulation cycle GO:0042698 43 30 0,000 0,19243078 0,22421013 ! adult locomotory behavior GO:0008344 47 30 0,000 0,19243078 0,2240966 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,19243078 0,22398319 ! response to heat GO:0009408 41 30 0,000 0,19243078 0,2238699 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,19243078 0,22375672 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,19243078 0,22364365 ! negative regulation of secretion GO:0051048 49 31 0,000 0,19816872 0,23019599 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,19816872 0,23007979 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,19816872 0,2299637 ! odontogenesis GO:0042476 50 31 0,000 0,19816872 0,22984773 ! segmentation GO:0035282 41 31 0,000 0,19816872 0,22973188 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,19816872 0,22961615 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,19816872 0,22950053 ! metanephros development GO:0001656 58 31 0,000 0,19816872 0,22938503 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,19816872 0,22926965 ! cell fate specification GO:0001708 37 31 0,000 0,19816872 0,22915438 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,19816872 0,22903923 ! RNA modification GO:0009451 40 31 0,000 0,19816872 0,22892419 ! regulation of muscle development GO:0048634 48 32 0,000 0,20386622 0,23538771 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,20386622 0,2352696 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,20386622 0,23515161 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,20386622 0,23503374 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,20386622 0,23491599 ! cytokine production GO:0001816 44 32 0,000 0,20386622 0,23479835 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,20386622 0,23468084 ! vesicle localization GO:0051648 47 32 0,000 0,20386622 0,23456344 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,20952356 0,2409521 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,20952356 0,24083168 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,20952356 0,24071138 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,20952356 0,24059121 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,20952356 0,24047115 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,20952356 0,24035122 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,20952356 0,2402314 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,20952356 0,2401117 ! female gonad development GO:0008585 49 33 0,000 0,20952356 0,23999213 ! positive regulation of cell development GO:0010720 54 33 0,000 0,20952356 0,23987267 ! lipid homeostasis GO:0055088 55 33 0,000 0,20952356 0,23975333 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,20952356 0,23963411 ! regulation of proteolysis GO:0030162 50 33 0,000 0,20952356 0,23951501 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,20952356 0,23939602 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,20952356 0,23927716 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,20952356 0,23915841 ! mRNA catabolic process GO:0006402 48 34 0,000 0,21514102 0,24544859 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,21514102 0,2453269 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,21514102 0,24520533 ! feeding behavior GO:0007631 45 34 0,000 0,21514102 0,24508388 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,21514102 0,24496255 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,21514102 0,24484134 ! neuron migration GO:0001764 46 34 0,000 0,21514102 0,24472025 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,21514102 0,24459928 ! female gamete generation GO:0007292 43 34 0,000 0,21514102 0,24447843 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,21514102 0,2443577 ! polyol metabolic process GO:0019751 44 34 0,000 0,21514102 0,24423709 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,21514102 0,2441166 ! embryonic organ development GO:0048568 45 34 0,000 0,21514102 0,24399623 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,21514102 0,24387597 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,22071888 0,25007558 ! Notch signaling pathway GO:0007219 56 35 0,000 0,22071888 0,24995245 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,22071888 0,24982944 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,22071888 0,24970656 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,22071888 0,24958379 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,22071888 0,24946115 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,22071888 0,24933862 ! glycogen metabolic process GO:0005977 48 35 0,000 0,22071888 0,24921622 ! pigment metabolic process GO:0042440 61 35 0,000 0,22071888 0,24909393 ! protein homooligomerization GO:0051260 52 35 0,000 0,22071888 0,24897177 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,22625742 0,25509415 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,22625742 0,25496917 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,22625742 0,2548443 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,22625742 0,25471956 ! organic ether metabolic process GO:0018904 46 36 0,000 0,22625742 0,25459494 ! tissue remodeling GO:0048771 62 36 0,000 0,22625742 0,25447045 ! neural tube development GO:0021915 50 36 0,000 0,22625742 0,25434607 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,22625742 0,25422182 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,22625742 0,25409769 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,22625742 0,25397368 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,22625742 0,25384979 ! glucan metabolic process GO:0044042 49 36 0,000 0,22625742 0,25372602 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,23175691 0,25976652 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,23175691 0,25963999 ! ion transmembrane transport GO:0034220 56 37 0,000 0,23175691 0,25951358 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,23175691 0,25938729 ! regulation of protein secretion GO:0050708 51 37 0,000 0,23175691 0,25926113 ! amino acid activation GO:0043038 52 37 0,000 0,23175691 0,2591351 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,23175691 0,25900918 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,23721762 0,26498326 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,23721762 0,26485463 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,23721762 0,26472612 ! phagocytosis GO:0006909 60 38 0,000 0,23721762 0,26459774 ! mesenchymal cell development GO:0014031 64 38 0,000 0,23721762 0,26446948 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,24263983 0,27038353 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,24263983 0,2702526 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,24263983 0,27012179 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,24263983 0,2699911 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,24263983 0,26986055 ! male sex differentiation GO:0046661 53 39 0,000 0,24263983 0,26973012 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,24263983 0,26959981 ! chromatin remodeling GO:0006338 68 39 0,000 0,24263983 0,26946963 ! JNK cascade GO:0007254 54 39 0,000 0,24263983 0,26933958 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,24802381 0,27518319 ! response to calcium ion GO:0051592 58 40 0,000 0,24802381 0,27505051 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,24802381 0,27491795 ! regulation of tube size GO:0035150 60 40 0,000 0,24802381 0,27478553 GO:0050880|regulation of blood vessel size, ! peptide metabolic process GO:0006518 56 40 0,000 0,24802381 0,27465323 ! inner ear development GO:0048839 57 40 0,000 0,24802381 0,27452106 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,24802381 0,27438901 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,24802381 0,27425709 ! double-strand break repair GO:0006302 67 40 0,000 0,24802381 0,2741253 ! B cell differentiation GO:0030183 62 40 0,000 0,24802381 0,27399364 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,24802381 0,2738621 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,24802381 0,27373069 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,25336981 0,27949668 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,25336981 0,27936269 ! endosome transport GO:0016197 71 41 0,000 0,25336981 0,27922883 ! striated muscle contraction GO:0006941 62 41 0,000 0,25336981 0,2790951 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,25336981 0,2789615 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,25336981 0,27882802 ! biopolymer methylation GO:0043414 62 41 0,000 0,25336981 0,27869468 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,25336981 0,27856146 ! mitochondrial transport GO:0006839 60 42 0,000 0,25867812 0,28426167 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,25867812 0,28412592 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,25867812 0,2839903 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,25867812 0,2838548 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,25867812 0,28371944 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,25867812 0,28358421 ! excretion GO:0007588 63 42 0,000 0,25867812 0,2834491 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,25867812 0,28331413 ! regulation of cell shape GO:0008360 78 42 0,000 0,25867812 0,28317928 ! positive regulation of binding GO:0051099 59 43 0,000 0,26394898 0,28881192 ! neuromuscular process GO:0050905 79 43 0,000 0,26394898 0,28867459 ! tRNA processing GO:0008033 49 43 0,000 0,26394898 0,28853739 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,26394898 0,28840031 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,26394898 0,28826337 ! methylation GO:0032259 64 43 0,000 0,26394898 0,28812656 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,26918267 0,29370026 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,26918267 0,293561 ! regulation of ion transport GO:0043269 57 44 0,000 0,26918267 0,29342187 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,26918267 0,29328288 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,26918267 0,29314401 ! RNA catabolic process GO:0006401 64 45 0,000 0,27437945 0,29866196 ! regulation of translational initiation GO:0006446 64 45 0,000 0,27437945 0,29852069 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,27437945 0,29837954 ! cell recognition GO:0008037 58 45 0,000 0,27437945 0,29823853 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,27953956 0,30370383 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,27953956 0,30356043 ! cell redox homeostasis GO:0045454 63 46 0,000 0,27953956 0,30341718 ! histone modification GO:0016570 68 46 0,000 0,27953956 0,30327406 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,27953956 0,30313107 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,28466328 0,30854173 ! viral infectious cycle GO:0019058 71 47 0,000 0,28466328 0,30839639 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,28466328 0,3082512 ! endocrine system development GO:0035270 83 47 0,000 0,28466328 0,30810614 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,28466328 0,30796121 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,28466328 0,30781643 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,28466328 0,30767178 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,28466328 0,30752726 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,28466328 0,30738288 ! chloride transport GO:0006821 67 48 0,000 0,28975085 0,31272968 ! response to temperature stimulus GO:0009266 62 48 0,000 0,28975085 0,312583 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,28975085 0,31243645 ! gastrulation GO:0007369 73 48 0,000 0,28975085 0,31229004 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,28975085 0,31214377 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,28975085 0,31199764 ! regulation of endocytosis GO:0030100 63 48 0,000 0,28975085 0,31185164 ! nuclear export GO:0051168 69 48 0,000 0,28975085 0,31170578 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,28975085 0,31156005 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,29480252 0,31684383 ! sensory perception of smell GO:0007608 61 49 0,000 0,29480252 0,31669584 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,29480252 0,31654799 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,29480252 0,31640028 ! RNA elongation GO:0006354 62 49 0,000 0,29480252 0,31625271 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,29480252 0,31610527 ! germ cell development GO:0007281 68 49 0,000 0,29480252 0,31595797 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,29480252 0,31581081 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,29981855 0,32103477 ! positive regulation of growth GO:0045927 67 50 0,000 0,29981855 0,32088538 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,29981855 0,32073613 ! proton transport GO:0015992 75 50 0,000 0,29981855 0,32058702 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,29981855 0,32043805 ! positive regulation of secretion GO:0051047 71 51 0,000 0,30479919 0,32560991 ! hydrogen transport GO:0006818 77 51 0,000 0,30479919 0,32545875 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,30479919 0,32530772 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,30479919 0,32515684 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,30479919 0,32500609 ! adult behavior GO:0030534 80 51 0,000 0,30479919 0,32485549 ! transition metal ion transport GO:0000041 74 52 0,000 0,30974469 0,3299735 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,30974469 0,32982073 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,30974469 0,32966811 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,30974469 0,32951562 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,31465528 0,3345849 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,31465528 0,33443029 ! kidney development GO:0001822 90 53 0,000 0,31465528 0,33427582 ! cell projection assembly GO:0030031 76 53 0,000 0,31465528 0,33412149 ! amino acid transport GO:0006865 84 54 0,000 0,31953122 0,3391425 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,31953122 0,33898607 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,31953122 0,33882979 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,31953122 0,33867364 ! exocytosis GO:0006887 74 55 0,000 0,32437275 0,34364685 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,32437275 0,34348864 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,32437275 0,34333057 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,3291801 0,34825862 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,33395353 0,35314626 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,33395353 0,35298397 ! camera-type eye development GO:0043010 88 57 0,000 0,33395353 0,35282182 ! secondary metabolic process GO:0019748 84 57 0,000 0,33395353 0,35265983 ! gonad development GO:0008406 79 57 0,000 0,33395353 0,35249798 ! viral reproductive process GO:0022415 87 58 0,000 0,33869325 0,35733692 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,33869325 0,35717308 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,33869325 0,35700939 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,34339952 0,36180435 ! activation of MAPK activity GO:0000187 84 59 0,000 0,34339952 0,36163869 ! lung development GO:0030324 94 59 0,000 0,34339952 0,36147318 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,34339952 0,36130782 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,34807257 0,36605711 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,34807257 0,36588981 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,34807257 0,36572266 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,34807257 0,36555566 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,35271262 0,37025971 ! urogenital system development GO:0001655 101 61 0,000 0,35271262 0,3700908 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,35271262 0,36992204 ! extracellular matrix organization GO:0030198 103 61 0,000 0,35271262 0,36975343 ! neurotransmitter transport GO:0006836 81 62 0,000 0,35731991 0,37441266 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,35731991 0,37424217 ! respiratory tube development GO:0030323 99 62 0,000 0,35731991 0,37407182 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,35731991 0,37390164 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,36189467 0,37851648 ! viral reproduction GO:0016032 92 63 0,000 0,36189467 0,37834443 ! regulation of lipase activity GO:0060191 109 63 0,000 0,36189467 0,37817253 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,36643713 0,38274541 ! respiratory system development GO:0060541 100 64 0,000 0,36643713 0,38257168 ! adaptive immune response GO:0002250 94 64 0,000 0,36643713 0,38239809 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,37094751 0,38692938 ! B cell activation GO:0042113 104 65 0,000 0,37094751 0,38675398 ! defense response to bacterium GO:0042742 73 65 0,000 0,37094751 0,38657874 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,37094751 0,38640366 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,37094751 0,38622873 ! activation of immune response GO:0002253 83 65 0,000 0,37094751 0,38605397 ! protein oligomerization GO:0051259 100 65 0,000 0,37094751 0,38587936 ! antigen processing and presentation GO:0019882 96 66 0,000 0,37542604 0,39036161 ! regulation of immune effector process GO:0002697 101 66 0,000 0,37542604 0,39018522 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,37987294 0,39462861 ! acute inflammatory response GO:0002526 92 68 0,000 0,38428843 0,39903539 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,38428843 0,39885531 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,38428843 0,39867541 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,38428843 0,39849566 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,38428843 0,39831608 ! rhythmic process GO:0048511 105 68 0,000 0,38428843 0,39813666 ! inorganic anion transport GO:0015698 93 68 0,000 0,38428843 0,3979574 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,38867273 0,4023165 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,38867273 0,40213553 ! response to drug GO:0042493 108 69 0,000 0,38867273 0,40195471 ! response to metal ion GO:0010038 103 70 0,000 0,39302606 0,40627413 ! humoral immune response GO:0006959 86 70 0,000 0,39302606 0,40609162 ! eye development GO:0001654 111 70 0,000 0,39302606 0,40590927 ! amine transport GO:0015837 101 70 0,000 0,39302606 0,40572708 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,39302606 0,40554506 ! regulation of catabolic process GO:0009894 106 70 0,000 0,39302606 0,4053632 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,39734864 0,40963777 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,39734864 0,40945424 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,39734864 0,40927088 ! regulation of blood pressure GO:0008217 107 73 0,000 0,4059024 0,41789415 ! tube morphogenesis GO:0035239 118 73 0,000 0,4059024 0,41770717 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,4059024 0,41752036 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,41013401 0,4216845 ! digestion GO:0007586 97 74 0,000 0,41013401 0,42149608 ! response to inorganic substance GO:0010035 115 75 0,000 0,41433573 0,42562401 ! response to nutrient GO:0007584 104 75 0,000 0,41433573 0,425434 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,41433573 0,42524416 ! tRNA metabolic process GO:0006399 95 76 0,000 0,41850775 0,42933444 ! response to unfolded protein GO:0006986 99 76 0,000 0,41850775 0,42914303 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,41850775 0,42895179 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,42265029 0,43300475 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,42265029 0,43281196 ! sex differentiation GO:0007548 105 77 0,000 0,42265029 0,43261934 ! protein ubiquitination GO:0016567 125 77 0,000 0,42265029 0,43242689 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,42265029 0,43223462 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,42676355 0,43624718 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,43084774 0,44022648 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,43084774 0,440031 ! T cell activation GO:0042110 134 79 0,000 0,43084774 0,43983569 ! regulation of lyase activity GO:0051339 133 79 0,000 0,43084774 0,43964056 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,43084774 0,43944559 ! chromatin assembly GO:0031497 102 80 0,000 0,43490307 0,44338522 GO:0006334|nucleosome assembly, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,43490307 0,44318878 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,43892974 0,44709406 ! mRNA transport GO:0051028 121 81 0,000 0,43892974 0,44689615 ! response to protein stimulus GO:0051789 111 81 0,000 0,43892974 0,44669841 ! vitamin metabolic process GO:0006766 103 81 0,000 0,43892974 0,44650084 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,44689788 0,45440545 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,44689788 0,45420465 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,45083975 0,45800858 ! sterol metabolic process GO:0016125 120 84 0,000 0,45083975 0,45780637 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,45475376 0,46157707 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,45475376 0,46137346 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,45475376 0,46117004 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,45864009 0,46490622 ! nucleosome organization GO:0034728 114 87 0,000 0,46249894 0,46861127 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,46249894 0,46840492 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,46249894 0,46819876 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,46249894 0,46799277 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,46633051 0,47166235 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,46633051 0,47145502 ! reproductive developmental process GO:0003006 127 89 0,000 0,47013499 0,47509247 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,47013499 0,47488383 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,47013499 0,47467536 ! leukocyte differentiation GO:0002521 143 90 0,000 0,47391256 0,47827946 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,47391256 0,47806968 ! hormone metabolic process GO:0042445 121 90 0,000 0,47391256 0,4778601 ! ATP metabolic process GO:0046034 137 91 0,000 0,47766341 0,48143113 ! response to virus GO:0009615 122 91 0,000 0,47766341 0,48122026 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,48138773 0,48475998 ! positive regulation of immune response GO:0050778 121 92 0,000 0,48138773 0,48454783 ! DNA recombination GO:0006310 146 92 0,000 0,48138773 0,48433587 ! sulfur metabolic process GO:0006790 118 92 0,000 0,48138773 0,48412409 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,48508572 0,48762987 ! electron transport chain GO:0022900 123 94 0,000 0,48875754 0,49110631 ! response to oxidative stress GO:0006979 141 94 0,000 0,48875754 0,49089186 ! angiogenesis GO:0001525 149 95 0,000 0,49240339 0,49433776 ! carboxylic acid transport GO:0046942 147 95 0,000 0,49240339 0,49412208 GO:0015849|organic acid transport, ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,49602345 0,4975377 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,49602345 0,49732081 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,4996179 0,5007064 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,50673069 0,50761349 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,51024938 0,51091579 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,51024938 0,51069346 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,51024938 0,51047132 ! divalent metal ion transport GO:0070838 171 100 0,000 0,51024938 0,51024938