pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6849-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by extracellular signals GO:0008624 23 23 4,000 5,572E-07 1,027E-03 ! cell junction assembly GO:0034329 18 17 3,000 5,938E-06 5,472E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 7,557E-06 4,643E-03 GO:0070667|negative regulation of mast cell proliferation, ! negative regulation of BMP signaling pathway GO:0030514 6 6 2,000 7,557E-06 3,482E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 1,316E-05 4,849E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 2,000 1,316E-05 4,041E-03 ! cell junction organization GO:0034330 23 22 3,000 1,776E-05 4,675E-03 ! regulation of DNA metabolic process GO:0051052 51 50 4,000 3,018E-05 6,952E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 3,327E-05 6,813E-03 GO:0051325|interphase, ! induction of apoptosis via death domain receptors GO:0008625 10 10 2,000 4,44E-05 8,183E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 4,44E-05 7,439E-03 ! regulation of BMP signaling pathway GO:0030510 10 10 2,000 4,44E-05 6,819E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 2,000 4,44E-05 6,295E-03 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 2,000 6,073E-05 7,995E-03 ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 6,073E-05 7,462E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 7,272E-05 8,376E-03 ! G1 phase GO:0051318 13 12 2,000 8,055E-05 8,733E-03 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 1,042E-04 0,01066619 ! actin filament bundle formation GO:0051017 13 13 2,000 1,042E-04 0,01010481 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 1,042E-04 9,6E-03 ! blastocyst development GO:0001824 13 13 2,000 1,042E-04 9,142E-03 ! striated muscle cell differentiation GO:0051146 16 15 2,000 1,64E-04 0,01373906 ! negative regulation of cell activation GO:0050866 15 15 2,000 1,64E-04 0,01314171 ! chromosome segregation GO:0007059 38 38 3,000 1,642E-04 0,01260797 ! developmental maturation GO:0021700 39 39 3,000 1,82E-04 0,01341346 ! cell cycle checkpoint GO:0000075 42 41 3,000 2,216E-04 0,01570738 ! myelination GO:0042552 17 17 2,000 2,426E-04 0,01655648 ! homeostasis of number of cells GO:0048872 44 43 3,000 2,671E-04 0,01758112 ! ensheathment of neurons GO:0007272 18 18 2,000 2,895E-04 0,01840108 GO:0008366|axon ensheathment, ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 3,42E-04 0,02101272 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 4,003E-04 0,02379865 ! actin filament organization GO:0007015 50 48 3,000 4,098E-04 0,02360219 ! mitotic sister chromatid segregation GO:0000070 21 21 2,000 4,646E-04 0,02594638 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 4,646E-04 0,02518325 ! DNA integrity checkpoint GO:0031570 21 21 2,000 4,646E-04 0,02446373 ! regulation of action potential in neuron GO:0019228 21 21 2,000 4,646E-04 0,02378418 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 5,312E-04 0,0264576 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 1,000 5,312E-04 0,02576134 ! memory GO:0007613 5 5 1,000 5,312E-04 0,0251008 ! erythrocyte maturation GO:0043249 5 5 1,000 5,312E-04 0,02447328 ! amyloid precursor protein catabolic process GO:0042987 5 5 1,000 5,312E-04 0,02387637 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 5,312E-04 0,02330788 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 5,312E-04 0,02276584 ! decidualization GO:0046697 5 5 1,000 5,312E-04 0,02224843 ! regulation of DNA replication initiation GO:0030174 5 5 1,000 5,312E-04 0,02175402 ! peptidyl-histidine modification GO:0018202 5 5 1,000 5,312E-04 0,02128111 ! blastocyst formation GO:0001825 5 5 1,000 5,312E-04 0,02082832 ! nucleus localization GO:0051647 5 5 1,000 5,312E-04 0,0203944 ! sister chromatid segregation GO:0000819 22 22 2,000 5,351E-04 0,0201277 ! spindle organization GO:0007051 22 22 2,000 5,351E-04 0,01972514 ! erythrocyte differentiation GO:0030218 23 22 2,000 5,351E-04 0,01933838 ! regulation of action potential GO:0001508 24 24 2,000 6,96E-04 0,0246683 ! erythrocyte homeostasis GO:0034101 25 24 2,000 6,96E-04 0,02420286 ! regulation of T cell proliferation GO:0042129 25 25 2,000 7,868E-04 0,02685333 ! negative regulation of immune system process GO:0002683 25 25 2,000 7,868E-04 0,02636509 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 7,93E-04 0,02609701 ! regulation of B cell proliferation GO:0030888 6 6 1,000 7,93E-04 0,02563917 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 7,93E-04 0,02519712 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 7,93E-04 0,02477005 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 7,93E-04 0,02435721 ! pathogenesis GO:0009405 6 6 1,000 7,93E-04 0,02395791 ! L-serine metabolic process GO:0006563 6 6 1,000 7,93E-04 0,02357149 ! focal adhesion formation GO:0048041 7 6 1,000 7,93E-04 0,02319734 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,93E-04 0,02283489 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 7,93E-04 0,02248358 ! erythrocyte development GO:0048821 6 6 1,000 7,93E-04 0,02214292 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 7,93E-04 0,02181243 ! maternal placenta development GO:0001893 6 6 1,000 7,93E-04 0,02149166 ! hemopoiesis GO:0030097 104 100 4,000 8,115E-04 0,02167464 ! glycolysis GO:0006096 26 26 2,000 8,848E-04 0,0232955 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 2,000 8,848E-04 0,0229674 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 9,027E-04 0,02310784 ! learning or memory GO:0007611 28 27 2,000 9,902E-04 0,0249996 ! keratinocyte differentiation GO:0030216 28 28 2,000 1,103E-03 0,02747742 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 1,103E-03 0,02711106 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,105E-03 0,02679352 ! SMAD protein nuclear translocation GO:0007184 7 7 1,000 1,105E-03 0,02644555 ! amyloid precursor protein metabolic process GO:0042982 7 7 1,000 1,105E-03 0,0261065 ! hemoglobin metabolic process GO:0020027 7 7 1,000 1,105E-03 0,02577604 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 1,105E-03 0,02545384 ! membrane protein ectodomain proteolysis GO:0006509 7 7 1,000 1,105E-03 0,0251396 GO:0033619|membrane protein proteolysis, ! myofibril assembly GO:0030239 7 7 1,000 1,105E-03 0,02483302 GO:0055002|striated muscle cell development, ! NLS-bearing substrate import into nucleus GO:0006607 7 7 1,000 1,105E-03 0,02453382 ! platelet activation GO:0030168 8 7 1,000 1,105E-03 0,02424175 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,105E-03 0,02395656 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,224E-03 0,02623423 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,224E-03 0,02593269 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 2,000 1,353E-03 0,02833848 ! striated muscle tissue development GO:0014706 69 67 3,000 1,456E-03 0,03014071 ! embryonic hindlimb morphogenesis GO:0035116 8 8 1,000 1,466E-03 0,03002459 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 1,000 1,466E-03 0,02969465 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 1,466E-03 0,02937188 ! Golgi organization GO:0007030 8 8 1,000 1,466E-03 0,02905605 ! cell-cell junction assembly GO:0007043 8 8 1,000 1,466E-03 0,02874695 ! plasma membrane fusion GO:0045026 8 8 1,000 1,466E-03 0,02844435 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,466E-03 0,02814805 ! muscle cell development GO:0055001 8 8 1,000 1,466E-03 0,02785787 ! chromatin silencing GO:0006342 8 8 1,000 1,466E-03 0,0275736 ! T cell homeostasis GO:0043029 8 8 1,000 1,466E-03 0,02729508 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,466E-03 0,02702213 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,466E-03 0,02675458 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,466E-03 0,02649228 ! epidermal cell differentiation GO:0009913 31 31 2,000 1,49E-03 0,0266662 ! negative regulation of cell motion GO:0051271 31 31 2,000 1,49E-03 0,0264098 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 1,624E-03 0,02850314 ! glucose catabolic process GO:0006007 32 32 2,000 1,636E-03 0,02844334 ! cell maturation GO:0048469 32 32 2,000 1,636E-03 0,02817751 ! wound healing GO:0042060 74 70 3,000 1,713E-03 0,0292314 ! muscle tissue development GO:0060537 72 70 3,000 1,713E-03 0,02896323 ! negative regulation of signal transduction GO:0009968 71 71 3,000 1,805E-03 0,03024837 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,876E-03 0,03115154 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 1,000 1,876E-03 0,03087341 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,876E-03 0,03060019 ! cerebral cortex development GO:0021987 9 9 1,000 1,876E-03 0,03033177 ! pigmentation during development GO:0048066 9 9 1,000 1,876E-03 0,03006801 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,876E-03 0,02980881 ! DNA replication initiation GO:0006270 9 9 1,000 1,876E-03 0,02955403 ! prostaglandin metabolic process GO:0006693 9 9 1,000 1,876E-03 0,02930357 GO:0006692|prostanoid metabolic process, ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 1,876E-03 0,02905732 ! actin filament-based movement GO:0030048 9 9 1,000 1,876E-03 0,02881518 ! muscle cell differentiation GO:0042692 35 34 2,000 1,953E-03 0,02974986 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 2,125E-03 0,03210453 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 2,125E-03 0,03184352 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 2,306E-03 0,03427926 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 2,000 2,306E-03 0,03400502 ! negative regulation of cell communication GO:0010648 76 76 3,000 2,32E-03 0,03393379 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,334E-03 0,03387259 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 2,334E-03 0,03360796 ! epidermis morphogenesis GO:0048730 10 10 1,000 2,334E-03 0,03334743 ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 2,334E-03 0,03309091 ! neuromuscular junction development GO:0007528 10 10 1,000 2,334E-03 0,03283831 ! embryo implantation GO:0007566 11 10 1,000 2,334E-03 0,03258954 ! synaptic vesicle transport GO:0048489 11 10 1,000 2,334E-03 0,0323445 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,334E-03 0,03210313 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 2,497E-03 0,0340864 ! hexose catabolic process GO:0019320 38 38 2,000 2,697E-03 0,03654526 ! negative regulation of kinase activity GO:0033673 38 38 2,000 2,697E-03 0,03627851 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 2,839E-03 0,0379196 ! heart contraction GO:0060047 11 11 1,000 2,839E-03 0,0376468 GO:0003015|heart process, ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 2,839E-03 0,03737789 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! apoptotic nuclear changes GO:0030262 11 11 1,000 2,839E-03 0,0371128 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 1,000 2,839E-03 0,03685144 GO:0060415|muscle tissue morphogenesis, ! hindbrain development GO:0030902 11 11 1,000 2,839E-03 0,03659374 ! positive regulation of protein modification process GO:0031401 39 39 2,000 2,906E-03 0,03719716 ! cytokine-mediated signaling pathway GO:0019221 39 39 2,000 2,906E-03 0,03694063 ! negative regulation of transferase activity GO:0051348 40 40 2,000 3,126E-03 0,03945648 ! myeloid cell differentiation GO:0030099 42 40 2,000 3,126E-03 0,03918807 ! organelle localization GO:0051640 41 40 2,000 3,126E-03 0,03892329 ! monosaccharide catabolic process GO:0046365 41 41 2,000 3,355E-03 0,04149794 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 3,391E-03 0,04166529 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 3,391E-03 0,04138936 ! heterophilic cell adhesion GO:0007157 12 12 1,000 3,391E-03 0,04111707 ! hindlimb morphogenesis GO:0035137 12 12 1,000 3,391E-03 0,04084833 ! actomyosin structure organization GO:0031032 12 12 1,000 3,391E-03 0,04058308 ! positive regulation of endocytosis GO:0045807 12 12 1,000 3,391E-03 0,04032125 ! glycoprotein catabolic process GO:0006516 13 12 1,000 3,391E-03 0,04006278 ! pallium development GO:0021543 13 12 1,000 3,391E-03 0,0398076 ! cell fate determination GO:0001709 12 12 1,000 3,391E-03 0,03955566 ! regulation of chromosome organization GO:0033044 12 12 1,000 3,391E-03 0,03930688 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 3,391E-03 0,03906121 ! negative regulation of translation GO:0017148 12 12 1,000 3,391E-03 0,0388186 ! forebrain development GO:0030900 43 42 2,000 3,594E-03 0,04089068 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 3,637E-03 0,04112176 ! heart development GO:0007507 90 87 3,000 3,792E-03 0,04260883 ! alcohol catabolic process GO:0046164 43 43 2,000 3,844E-03 0,0429345 ! positive regulation of transferase activity GO:0051347 91 88 3,000 3,951E-03 0,04386135 GO:0033674|positive regulation of kinase activity, ! positive regulation of DNA replication GO:0045740 14 13 1,000 3,989E-03 0,04401924 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 3,989E-03 0,04375722 ! vasculogenesis GO:0001570 13 13 1,000 3,989E-03 0,0434983 ! regulation of DNA recombination GO:0000018 13 13 1,000 3,989E-03 0,04324243 ! negative regulation of DNA replication GO:0008156 13 13 1,000 3,989E-03 0,04298955 ! coenzyme catabolic process GO:0009109 13 13 1,000 3,989E-03 0,04273961 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,989E-03 0,04249256 ! cell-cell junction organization GO:0045216 13 13 1,000 3,989E-03 0,04224835 ! protein import into nucleus GO:0006606 44 44 2,000 4,104E-03 0,04321795 ! nuclear import GO:0051170 45 45 2,000 4,374E-03 0,04580327 ! acetyl-CoA metabolic process GO:0006084 14 14 1,000 4,632E-03 0,04822543 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 4,632E-03 0,0479545 ! regulation of membrane potential GO:0042391 46 46 2,000 4,655E-03 0,04792805 ! protein localization in nucleus GO:0034504 48 48 2,000 5,249E-03 0,05374455 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 5,319E-03 0,0541581 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 5,319E-03 0,05386053 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 5,319E-03 0,05356621 ! leukocyte homeostasis GO:0001776 15 15 1,000 5,319E-03 0,05327509 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 5,319E-03 0,05298711 ! regulation of cell growth GO:0001558 97 96 3,000 5,389E-03 0,05339763 ! cell cycle arrest GO:0007050 49 49 2,000 5,562E-03 0,05482134 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 5,562E-03 0,05452974 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 6,05E-03 0,05899536 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 6,05E-03 0,05868486 ! learning GO:0007612 16 16 1,000 6,05E-03 0,05837761 ! positive regulation of mitosis GO:0045840 16 16 1,000 6,05E-03 0,05807356 GO:0051785|positive regulation of nuclear division, ! fatty acid beta-oxidation GO:0006635 16 16 1,000 6,05E-03 0,05777266 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 6,05E-03 0,05747486 ! cofactor catabolic process GO:0051187 16 16 1,000 6,05E-03 0,05718012 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 6,05E-03 0,05688838 ! muscle organ development GO:0007517 102 100 3,000 6,225E-03 0,05823493 ! cell fate commitment GO:0045165 52 52 2,000 6,569E-03 0,06114714 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 6,824E-03 0,06320202 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 6,824E-03 0,06288601 ! regulation of transmembrane transport GO:0034762 17 17 1,000 6,824E-03 0,06257315 ! leukocyte adhesion GO:0007159 17 17 1,000 6,824E-03 0,06226338 ! glucose transport GO:0015758 17 17 1,000 6,824E-03 0,06195666 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 6,824E-03 0,06165295 ! pigmentation GO:0043473 17 17 1,000 6,824E-03 0,06135221 ! gene silencing GO:0016458 17 17 1,000 6,824E-03 0,06105438 ! response to hypoxia GO:0001666 53 53 2,000 6,927E-03 0,06167729 ! carbohydrate catabolic process GO:0016052 53 53 2,000 6,927E-03 0,06138077 ! regulation of T cell activation GO:0050863 53 53 2,000 6,927E-03 0,06108708 ! response to oxygen levels GO:0070482 55 54 2,000 7,297E-03 0,06403965 ! meiosis I GO:0007127 18 18 1,000 7,641E-03 0,06674241 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 7,641E-03 0,06642759 ! hexose transport GO:0008645 18 18 1,000 7,641E-03 0,06611572 GO:0015749|monosaccharide transport, ! telencephalon development GO:0021537 19 18 1,000 7,641E-03 0,06580677 ! regulation of microtubule-based process GO:0032886 18 18 1,000 7,641E-03 0,06550069 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 7,641E-03 0,06519745 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 7,678E-03 0,0652105 ! in utero embryonic development GO:0001701 55 55 2,000 7,678E-03 0,06491137 ! DNA damage checkpoint GO:0000077 19 19 1,000 8,5E-03 0,07153091 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 8,5E-03 0,07120577 ! glial cell differentiation GO:0010001 19 19 1,000 8,5E-03 0,07088357 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 8,5E-03 0,07056427 ! peripheral nervous system development GO:0007422 19 19 1,000 8,5E-03 0,07024784 ! placenta development GO:0001890 19 19 1,000 8,5E-03 0,06993423 ! protein localization in organelle GO:0033365 59 59 2,000 9,319E-03 0,07633469 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 9,4E-03 0,07665434 ! nucleus organization GO:0006997 20 20 1,000 9,4E-03 0,07631666 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 9,4E-03 0,07598193 ! lipid oxidation GO:0034440 20 20 1,000 9,4E-03 0,07565013 GO:0019395|fatty acid oxidation, ! single fertilization GO:0007338 21 20 1,000 9,4E-03 0,07532122 ! regulation of B cell activation GO:0050864 20 20 1,000 9,4E-03 0,07499516 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01021088 0,08111492 ! carboxylic acid catabolic process GO:0046395 63 61 2,000 0,01021088 0,08076678 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 2,000 0,01021088 0,08042163 ! mammary gland development GO:0030879 23 21 1,000 0,01034038 0,08109497 ! Notch signaling pathway GO:0007219 22 21 1,000 0,01034038 0,08075135 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01034038 0,08041062 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01034038 0,08007276 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 0,01034038 0,07973773 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01034038 0,07940549 ! axonogenesis GO:0007409 66 62 2,000 0,01067473 0,08163291 ! protein import GO:0017038 62 62 2,000 0,01067473 0,08129558 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,01067473 0,08096103 ! glucose metabolic process GO:0006006 63 63 2,000 0,01115067 0,08422409 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,0113209 0,08516091 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,0113209 0,08481473 ! respiratory gaseous exchange GO:0007585 22 22 1,000 0,0113209 0,08447135 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 1,000 0,0113209 0,08413074 ! fatty acid catabolic process GO:0009062 23 22 1,000 0,0113209 0,08379287 ! aerobic respiration GO:0009060 22 22 1,000 0,0113209 0,0834577 ! cytokinesis GO:0000910 23 22 1,000 0,0113209 0,08312519 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 0,01163874 0,08511986 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,01213902 0,0884277 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01234078 0,08954353 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01234078 0,08919238 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 0,01265154 0,09108119 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01317635 0,09449033 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! gliogenesis GO:0042063 24 24 1,000 0,01339939 0,09571738 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 0,01339939 0,09534781 ! fertilization GO:0009566 25 24 1,000 0,01339939 0,09498109 ! maintenance of protein location GO:0045185 25 24 1,000 0,01339939 0,09461718 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01339939 0,09425604 ! response to radiation GO:0009314 70 68 2,000 0,0137135 0,09609879 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01426303 0,09957107 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01449614 0,10081656 ! cellular component disassembly GO:0022411 26 25 1,000 0,01449614 0,10043755 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01449614 0,10006138 ! heart morphogenesis GO:0003007 25 25 1,000 0,01449614 0,09968802 ! icosanoid metabolic process GO:0006690 25 25 1,000 0,01449614 0,09931743 ! regulation of endocytosis GO:0030100 25 25 1,000 0,01449614 0,09894959 ! cell part morphogenesis GO:0032990 75 70 2,000 0,01482497 0,10082075 ! regulation of cell activation GO:0050865 71 71 2,000 0,01539937 0,10434203 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01563042 0,10551965 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01563042 0,10513454 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01563042 0,10475223 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01563042 0,10437269 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01563042 0,1039959 ! synapse organization GO:0050808 26 26 1,000 0,01563042 0,10362181 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01680164 0,11098715 ! carbohydrate transport GO:0008643 28 28 1,000 0,0180092 0,11853914 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,0180092 0,1181173 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 0,0180092 0,11769844 ! developmental growth GO:0048589 28 28 1,000 0,0180092 0,11728254 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,01910879 0,1240053 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,01925254 0,12449975 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01925254 0,12406443 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01925254 0,12363215 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01925254 0,12320288 ! response to UV GO:0009411 29 29 1,000 0,01925254 0,12277657 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01977109 0,12564867 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,01977109 0,12521688 ! nuclear transport GO:0051169 79 79 2,000 0,02044601 0,12904795 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 2,000 0,02044601 0,12860751 ! regulation of ossification GO:0030278 30 30 1,000 0,02053107 0,12870326 ! vesicle organization GO:0016050 30 30 1,000 0,02053107 0,12826698 ! establishment of organelle localization GO:0051656 31 30 1,000 0,02053107 0,12783365 ! neuron projection development GO:0031175 85 80 2,000 0,02113358 0,13114206 ! lipid catabolic process GO:0016042 82 81 2,000 0,0218338 0,13503254 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02184423 0,13464517 ! membrane fusion GO:0006944 31 31 1,000 0,02184423 0,13419636 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,02184423 0,13375052 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,02184423 0,13330764 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,02319145 0,14106216 ! muscle fiber development GO:0048747 32 32 1,000 0,02319145 0,14059814 ! lipid modification GO:0030258 32 32 1,000 0,02319145 0,14013716 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02319145 0,1396792 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02319145 0,13922422 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02319145 0,13877219 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,02319145 0,13832309 ! maintenance of location GO:0051235 33 32 1,000 0,02319145 0,13787689 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,02327222 0,13791225 ! negative regulation of cell size GO:0045792 33 33 1,000 0,02457217 0,14514909 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,02457217 0,14468536 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,02457217 0,14422458 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,0247613 0,14487327 ! hexose metabolic process GO:0019318 87 86 2,000 0,02552483 0,14886794 ! regulation of actin filament length GO:0030832 34 34 1,000 0,02598586 0,15107868 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,02598586 0,15060359 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02598586 0,15013148 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02598586 0,14966232 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02598586 0,14919608 ! male gamete generation GO:0048232 90 88 2,000 0,02708986 0,15505159 GO:0007283|spermatogenesis, ! regulation of cellular component size GO:0032535 35 35 1,000 0,02743196 0,15652354 ! mesoderm development GO:0007498 35 35 1,000 0,02743196 0,15604045 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,02743196 0,15556032 GO:0048609|reproductive process in a multicellular organism, ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02743196 0,15508314 ! regulation of Ras protein signal transduction GO:0046578 90 90 2,000 0,02870545 0,16178635 ! brain development GO:0007420 91 90 2,000 0,02870545 0,1612931 ! regulation of mitosis GO:0007088 37 36 1,000 0,02890994 0,16194837 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,02890994 0,16145762 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02890994 0,16096983 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02890994 0,16048498 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,02890994 0,16000305 ! coagulation GO:0050817 39 36 1,000 0,02890994 0,159524 GO:0007596|blood coagulation, ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,02953217 0,16247102 ! meiosis GO:0007126 37 37 1,000 0,03041926 0,16685325 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of growth GO:0045926 37 37 1,000 0,03041926 0,16635814 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03041926 0,16586595 ! cellular amino acid catabolic process GO:0009063 38 37 1,000 0,03041926 0,16537667 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,03041926 0,16489027 ! tissue morphogenesis GO:0048729 94 93 2,000 0,03122341 0,1687529 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,0319594 0,17222563 ! meiotic cell cycle GO:0051321 38 38 1,000 0,0319594 0,17172352 ! axon guidance GO:0007411 39 38 1,000 0,0319594 0,17122432 ! regulation of neurological system process GO:0031644 38 38 1,000 0,0319594 0,17072802 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,0319594 0,17023458 ! blood vessel development GO:0001568 95 94 2,000 0,03208788 0,17042643 ! epidermis development GO:0008544 94 94 2,000 0,03208788 0,1699367 ! hemostasis GO:0007599 42 39 1,000 0,03352983 0,17706441 ! limb development GO:0060173 39 39 1,000 0,03352983 0,17655851 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! positive regulation of cell motion GO:0051272 39 39 1,000 0,03352983 0,17605549 ! vasculature development GO:0001944 97 96 2,000 0,03385445 0,17725498 ! DNA catabolic process GO:0006308 41 40 1,000 0,03513005 0,18341269 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,03513005 0,18289458 ! blood circulation GO:0008015 99 98 2,000 0,03567101 0,18518781 GO:0003013|circulatory system process, ! rRNA transcription GO:0009303 5 5 0,000 0,03652898 0,1891093 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03652898 0,18857958 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03652898 0,18805282 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03652898 0,187529 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03652898 0,18700808 ! reproductive cellular process GO:0048610 5 5 0,000 0,03652898 0,18649006 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03652898 0,18597489 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03652898 0,18546256 ! prostate gland development GO:0030850 5 5 0,000 0,03652898 0,18495305 ! metencephalon development GO:0022037 5 5 0,000 0,03652898 0,18444633 ! water transport GO:0006833 5 5 0,000 0,03652898 0,18394238 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03652898 0,18344117 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03652898 0,18294269 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03652898 0,18244691 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03652898 0,18195381 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03652898 0,18146337 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03652898 0,18097557 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03652898 0,18049038 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03652898 0,18000778 GO:0010469|regulation of receptor activity, ! filopodium assembly GO:0046847 7 5 0,000 0,03652898 0,17952776 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03652898 0,17905029 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03652898 0,17857536 ! GTP metabolic process GO:0046039 5 5 0,000 0,03652898 0,17810294 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03652898 0,17763301 ! mRNA stabilization GO:0048255 5 5 0,000 0,03652898 0,17716555 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03652898 0,17670055 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03652898 0,17623798 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03652898 0,17577783 ! social behavior GO:0035176 5 5 0,000 0,03652898 0,17532008 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03652898 0,1748647 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03652898 0,17441168 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03652898 0,17396101 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03652898 0,17351266 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03652898 0,17306661 ! response to lipid GO:0033993 5 5 0,000 0,03652898 0,17262285 ! hippocampus development GO:0021766 6 5 0,000 0,03652898 0,17218136 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03652898 0,17174212 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03652898 0,17130512 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03652898 0,17087033 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03652898 0,17043775 ! heart looping GO:0001947 5 5 0,000 0,03652898 0,17000735 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03652898 0,16957912 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03652898 0,16915304 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03652898 0,1687291 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03652898 0,16830728 ! pH reduction GO:0045851 5 5 0,000 0,03652898 0,16788756 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03652898 0,16746993 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03652898 0,16705437 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03652898 0,16664087 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03652898 0,16622941 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03652898 0,16581998 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03652898 0,16541256 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03652898 0,16500713 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03652898 0,16460369 ! adrenal gland development GO:0030325 5 5 0,000 0,03652898 0,16420222 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03652898 0,1638027 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03652898 0,16340512 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03652898 0,16300947 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03652898 0,16261573 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03652898 0,16222388 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03652898 0,16183392 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03652898 0,16144583 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03652898 0,16105959 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03652898 0,1606752 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03652898 0,16029264 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03652898 0,1599119 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03652898 0,15953296 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03652898 0,15915582 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03652898 0,15878045 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03652898 0,15840685 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03652898 0,158035 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03652898 0,1576649 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03652898 0,15729652 ! response to ATP GO:0033198 5 5 0,000 0,03652898 0,15692986 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03652898 0,15656491 ! regulation of appetite GO:0032098 5 5 0,000 0,03652898 0,15620165 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03652898 0,15584007 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03652898 0,15548016 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,03652898 0,15512191 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03652898 0,15476531 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03652898 0,15441034 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03652898 0,154057 ! receptor clustering GO:0043113 5 5 0,000 0,03652898 0,15370527 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03652898 0,15335515 ! fear response GO:0042596 5 5 0,000 0,03652898 0,15300661 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03652898 0,15265966 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03652898 0,15231428 ! retinol metabolic process GO:0042572 5 5 0,000 0,03652898 0,15197045 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03652898 0,15162818 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03652898 0,15128744 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03652898 0,15094823 ! parturition GO:0007567 5 5 0,000 0,03652898 0,15061054 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03652898 0,15027435 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03652898 0,14993967 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03652898 0,14960647 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03652898 0,14927475 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03652898 0,14894449 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03652898 0,1486157 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03652898 0,14828835 ! response to UV-B GO:0010224 5 5 0,000 0,03652898 0,14796244 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03652898 0,14763796 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03652898 0,1473149 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03652898 0,14699325 ! interaction with symbiont GO:0051702 5 5 0,000 0,03652898 0,14667301 ! cellular extravasation GO:0045123 5 5 0,000 0,03652898 0,14635415 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03652898 0,14603668 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03652898 0,14572058 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03652898 0,14540585 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03652898 0,14509248 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03652898 0,14478045 ! response to amine stimulus GO:0014075 5 5 0,000 0,03652898 0,14446976 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03652898 0,14416041 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03652898 0,14385237 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03652898 0,14354565 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03652898 0,14324023 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03652898 0,14293612 ! neuron recognition GO:0008038 5 5 0,000 0,03652898 0,14263328 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03652898 0,14233173 ! hair follicle maturation GO:0048820 5 5 0,000 0,03652898 0,14203146 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03652898 0,14173244 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03652898 0,14143469 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03652898 0,14113818 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03652898 0,14084291 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03652898 0,14054887 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03652898 0,14025606 ! postreplication repair GO:0006301 5 5 0,000 0,03652898 0,13996447 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03652898 0,13967409 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03652898 0,13938491 ! histone methylation GO:0016571 5 5 0,000 0,03652898 0,13909692 ! DNA methylation GO:0006306 5 5 0,000 0,03652898 0,13881012 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03652898 0,13852451 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03652898 0,13824006 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03652898 0,13795678 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03652898 0,13767466 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03652898 0,13739369 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03652898 0,13711387 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03652898 0,13683518 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03652898 0,13655763 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03652898 0,13628119 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03652898 0,13600588 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03652898 0,13573167 ! sterol catabolic process GO:0016127 5 5 0,000 0,03652898 0,13545857 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03652898 0,13518657 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03652898 0,13491565 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03652898 0,13464582 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03652898 0,13437707 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! zymogen activation GO:0031638 5 5 0,000 0,03652898 0,13410938 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03652898 0,13384276 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03652898 0,1335772 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03652898 0,13331269 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,03652898 0,13304923 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03652898 0,13278681 ! nucleosome positioning GO:0016584 5 5 0,000 0,03652898 0,13252541 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03652898 0,13226505 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03652898 0,13200571 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03652898 0,13174738 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03652898 0,13149006 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03652898 0,13123374 ! NADPH regeneration GO:0006740 5 5 0,000 0,03652898 0,13097842 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03652898 0,1307241 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03652898 0,13047076 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03652898 0,13021839 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03652898 0,12996701 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03652898 0,12971659 ! sarcomere organization GO:0045214 5 5 0,000 0,03652898 0,12946713 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03652898 0,12921864 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03652898 0,12897109 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03652898 0,12872449 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03652898 0,12847884 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03652898 0,12823411 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03652898 0,12799032 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03652898 0,12774746 ! spleen development GO:0048536 5 5 0,000 0,03652898 0,12750551 ! male genitalia development GO:0030539 5 5 0,000 0,03652898 0,12726448 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03652898 0,12702436 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03652898 0,12678514 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03652898 0,12654682 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03652898 0,1263094 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03652898 0,12607287 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03652898 0,12583722 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03652898 0,12560244 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03652898 0,12536855 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03652898 0,12513552 ! ATP catabolic process GO:0006200 5 5 0,000 0,03652898 0,12490336 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03652898 0,12467206 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03652898 0,12444161 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03652898 0,12421201 ! embryonic gut development GO:0048566 5 5 0,000 0,03652898 0,12398326 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03652898 0,12375535 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03652898 0,12352828 ! activation of innate immune response GO:0002218 5 5 0,000 0,03652898 0,12330203 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03652898 0,12307662 ! catecholamine transport GO:0051937 5 5 0,000 0,03652898 0,12285203 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03652898 0,12262825 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03652898 0,12240529 ! muscle adaptation GO:0043500 5 5 0,000 0,03652898 0,12218314 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03652898 0,12196179 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03652898 0,12174125 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03652898 0,1215215 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03652898 0,12130254 ! defense response to fungus GO:0050832 5 5 0,000 0,03652898 0,12108437 ! lysogeny GO:0030069 5 5 0,000 0,03652898 0,12086698 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03652898 0,12065038 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03652898 0,12043454 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03652898 0,12021948 ! response to nicotine GO:0035094 5 5 0,000 0,03652898 0,12000519 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03652898 0,11979166 ! mitochondrion localization GO:0051646 5 5 0,000 0,03652898 0,11957888 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03652898 0,11936686 ! anti-apoptosis GO:0006916 100 99 2,000 0,03659797 0,11938064 ! ectoderm development GO:0007398 99 99 2,000 0,03659797 0,11916972 ! amine catabolic process GO:0009310 42 41 1,000 0,03675954 0,11948471 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,03753735 0,12179812 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,0384178 0,12443587 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,0384178 0,12421756 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,0384178 0,12400002 ! mitochondrion organization GO:0007005 44 43 1,000 0,04010434 0,1292173 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,04181865 0,13450572 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,04181865 0,13427139 ! amine biosynthetic process GO:0009309 46 45 1,000 0,04356026 0,13962011 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,04356026 0,13937771 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,04356026 0,13913616 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,04356026 0,13889544 ! protein processing GO:0016485 45 45 1,000 0,04356026 0,13865555 ! axon extension GO:0048675 7 6 0,000 0,04367618 0,13878484 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04367618 0,13854597 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,04367618 0,13830791 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,04367618 0,13807068 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04367618 0,13783426 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04367618 0,13759864 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04367618 0,13736383 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04367618 0,13712982 ! virus-host interaction GO:0019048 6 6 0,000 0,04367618 0,13689661 ! regulation of S phase GO:0033261 6 6 0,000 0,04367618 0,13666419 ! myotube differentiation GO:0014902 6 6 0,000 0,04367618 0,13643255 ! bone remodeling GO:0046849 6 6 0,000 0,04367618 0,1362017 ! N-glycan processing GO:0006491 6 6 0,000 0,04367618 0,13597163 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04367618 0,13574234 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04367618 0,13551381 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04367618 0,13528606 ! RNA methylation GO:0001510 6 6 0,000 0,04367618 0,13505907 ! cartilage condensation GO:0001502 7 6 0,000 0,04367618 0,13483284 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04367618 0,13460737 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,04367618 0,13438265 ! artery development GO:0060840 6 6 0,000 0,04367618 0,13415868 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04367618 0,13393545 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04367618 0,13371297 ! androgen metabolic process GO:0008209 6 6 0,000 0,04367618 0,13349122 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04367618 0,13327021 ! limbic system development GO:0021761 7 6 0,000 0,04367618 0,13304993 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04367618 0,13283037 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04367618 0,13261154 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04367618 0,13239343 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04367618 0,13217604 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04367618 0,13195935 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04367618 0,13174338 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04367618 0,13152811 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04367618 0,13131355 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04367618 0,13109968 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04367618 0,13088651 ! arginine metabolic process GO:0006525 6 6 0,000 0,04367618 0,13067404 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04367618 0,13046225 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04367618 0,13025114 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04367618 0,13004072 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04367618 0,12983098 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04367618 0,12962191 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04367618 0,12941351 GO:0005978|glycogen biosynthetic process, ! ER overload response GO:0006983 6 6 0,000 0,04367618 0,12920579 ! V(D)J recombination GO:0033151 6 6 0,000 0,04367618 0,12899873 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04367618 0,12879233 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04367618 0,12858659 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04367618 0,12838151 ! regulation of heart rate GO:0002027 6 6 0,000 0,04367618 0,12817708 ! lipid digestion GO:0044241 6 6 0,000 0,04367618 0,1279733 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04367618 0,12777017 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04367618 0,12756768 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04367618 0,12736583 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04367618 0,12716462 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04367618 0,12696405 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04367618 0,1267641 ! ruffle organization GO:0031529 6 6 0,000 0,04367618 0,12656479 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,04367618 0,1263661 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04367618 0,12616803 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04367618 0,12597059 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04367618 0,12577376 ! L-amino acid transport GO:0015807 6 6 0,000 0,04367618 0,12557754 ! bone mineralization GO:0030282 6 6 0,000 0,04367618 0,12538194 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04367618 0,12518695 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04367618 0,12499256 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04367618 0,12479877 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04367618 0,12460558 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04367618 0,12441299 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04367618 0,124221 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04367618 0,12402959 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04367618 0,12383878 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04367618 0,12364855 ! regulation of organ growth GO:0046620 6 6 0,000 0,04367618 0,1234589 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04367618 0,12326984 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04367618 0,12308135 ! response to dsRNA GO:0043331 6 6 0,000 0,04367618 0,12289344 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04367618 0,12270611 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04367618 0,12251934 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04367618 0,12233314 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04367618 0,1221475 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04367618 0,12196243 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04367618 0,12177792 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04367618 0,12159397 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04367618 0,12141057 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04367618 0,12122772 ! renal water homeostasis GO:0003091 6 6 0,000 0,04367618 0,12104542 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04367618 0,12086367 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04367618 0,12068247 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04367618 0,1205018 ! ribosome assembly GO:0042255 6 6 0,000 0,04367618 0,12032168 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04367618 0,1201421 ! diencephalon development GO:0021536 6 6 0,000 0,04367618 0,11996305 ! fucose catabolic process GO:0019317 6 6 0,000 0,04367618 0,11978453 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04367618 0,11960655 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04367618 0,11942909 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04367618 0,11925216 ! regulation of cell division GO:0051302 6 6 0,000 0,04367618 0,11907575 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04367618 0,11889986 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04367618 0,11872449 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04367618 0,11854964 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04367618 0,1183753 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04367618 0,11820148 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04367618 0,11802816 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04367618 0,11785535 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04367618 0,11768305 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04367618 0,11751125 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04367618 0,11733995 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04367618 0,11716915 ! thymus development GO:0048538 6 6 0,000 0,04367618 0,11699885 ! lymph node development GO:0048535 6 6 0,000 0,04367618 0,11682904 ! organic cation transport GO:0015695 6 6 0,000 0,04367618 0,11665972 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04367618 0,11649089 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04367618 0,11632255 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04367618 0,1161547 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04367618 0,11598733 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04367618 0,11582044 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04367618 0,11565403 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04367618 0,1154881 ! alditol metabolic process GO:0019400 6 6 0,000 0,04367618 0,11532264 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04367618 0,11515766 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04367618 0,11499315 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04367618 0,11482911 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04367618 0,11466554 ! localization within membrane GO:0051668 6 6 0,000 0,04367618 0,11450243 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,04532868 0,11866586 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,04532868 0,11849754 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,04532868 0,1183297 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,04532868 0,11816233 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,04712344 0,12266738 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,04894407 0,12722697 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,04894407 0,12704777 ! respiratory burst GO:0045730 7 7 0,000 0,0507714 0,13160575 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,0507714 0,13142091 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,0507714 0,13123659 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,0507714 0,13105279 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,0507714 0,13086949 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,0507714 0,13068672 ! regulation of chemokine production GO:0032642 7 7 0,000 0,0507714 0,13050445 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,0507714 0,13032269 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,0507714 0,13014143 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,0507714 0,12996068 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,0507714 0,12978043 ! gene silencing by RNA GO:0031047 7 7 0,000 0,0507714 0,12960068 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,0507714 0,12942142 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,0507714 0,12924266 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,0507714 0,1290644 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,0507714 0,12888662 ! axis specification GO:0009798 7 7 0,000 0,0507714 0,12870934 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,0507714 0,12853254 ! visual behavior GO:0007632 7 7 0,000 0,0507714 0,12835623 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,0507714 0,1281804 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,0507714 0,12800505 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,0507714 0,12783018 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,0507714 0,12765578 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,0507714 0,12748186 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,0507714 0,12730842 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,0507714 0,12713545 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,0507714 0,12696294 ! digestive system development GO:0055123 7 7 0,000 0,0507714 0,12679091 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,0507714 0,12661934 ! protein targeting to ER GO:0045047 8 7 0,000 0,0507714 0,12644823 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,0507714 0,12627758 ! endoderm development GO:0007492 7 7 0,000 0,0507714 0,1261074 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,0507714 0,12593767 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,0507714 0,1257684 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,0507714 0,12559958 ! response to hexose stimulus GO:0009746 7 7 0,000 0,0507714 0,12543122 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,0507714 0,1252633 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,0507714 0,12509584 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,0507714 0,12492882 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,0507714 0,12476225 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,0507714 0,12459612 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,0507714 0,12443044 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,0507714 0,12426519 ! response to X-ray GO:0010165 7 7 0,000 0,0507714 0,12410038 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,0507714 0,12393601 ! UV protection GO:0009650 7 7 0,000 0,0507714 0,12377208 ! DNA integration GO:0015074 7 7 0,000 0,0507714 0,12360857 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,0507714 0,1234455 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,0507714 0,12328286 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,0507714 0,12312064 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,0507714 0,12295886 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,0507714 0,12279749 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,0507714 0,12263655 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,0507714 0,12247603 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,0507714 0,12231593 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,0507714 0,12215625 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,0507714 0,12199699 ! axon cargo transport GO:0008088 7 7 0,000 0,0507714 0,12183814 ! eating behavior GO:0042755 7 7 0,000 0,0507714 0,1216797 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,0507714 0,12152167 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,0507714 0,12136406 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,0507714 0,12120685 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,0507714 0,12105005 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,0507714 0,12089365 ! cranial nerve development GO:0021545 7 7 0,000 0,0507714 0,12073766 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,0507714 0,12058207 ! induction of an organ GO:0001759 7 7 0,000 0,0507714 0,12042688 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,0507714 0,12027209 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,0507714 0,1201177 ! autonomic nervous system development GO:0048483 7 7 0,000 0,0507714 0,1199637 ! intracellular lipid transport GO:0032365 7 7 0,000 0,0507714 0,1198101 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,0507714 0,11965689 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,0507714 0,11950407 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,0507714 0,11935164 ! natural killer cell activation GO:0030101 7 7 0,000 0,0507714 0,1191996 ! response to gamma radiation GO:0010332 8 7 0,000 0,0507714 0,11904795 ! NADP metabolic process GO:0006739 7 7 0,000 0,0507714 0,11889668 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,0507714 0,1187458 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,0507714 0,1185953 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,0507714 0,11844518 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,0507714 0,11829543 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,0507714 0,11814607 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,0507714 0,11799709 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,0507714 0,11784847 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,0507714 0,11770024 ! cell-cell recognition GO:0009988 8 7 0,000 0,0507714 0,11755237 ! hormone catabolic process GO:0042447 7 7 0,000 0,0507714 0,11740488 ! dopamine metabolic process GO:0042417 7 7 0,000 0,0507714 0,11725776 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,0507714 0,117111 ! oxygen transport GO:0015671 7 7 0,000 0,0507714 0,11696461 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,0507714 0,11681859 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,0507714 0,11667293 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,0507714 0,11652763 ! regulation of axon extension GO:0030516 7 7 0,000 0,0507714 0,1163827 ! cell killing GO:0001906 7 7 0,000 0,0507714 0,11623812 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,0507714 0,11609391 ! adult feeding behavior GO:0008343 7 7 0,000 0,0507714 0,11595005 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,0507714 0,11580655 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,0507714 0,1156634 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,0507714 0,1155206 ! response to cold GO:0009409 7 7 0,000 0,0507714 0,11537816 ! ossification GO:0001503 50 49 1,000 0,0507901 0,1152785 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,0507901 0,11513671 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,0507901 0,11499526 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,0507901 0,11485417 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 1,000 0,0507901 0,11471341 ! negative regulation of transport GO:0051051 51 50 1,000 0,05266106 0,11879356 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,05266106 0,11864834 ! nitrogen compound catabolic process GO:0044270 51 50 1,000 0,05266106 0,11850347 ! protein maturation GO:0051604 51 51 1,000 0,05455652 0,1226191 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,05647601 0,12677866 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,05647601 0,12662443 ! response to light stimulus GO:0009416 53 52 1,000 0,05647601 0,12647057 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,057815 0,12931194 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,057815 0,1291552 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,057815 0,12899884 ! positive regulation of translation GO:0045727 8 8 0,000 0,057815 0,12884286 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,057815 0,12868725 ! superoxide anion generation GO:0042554 8 8 0,000 0,057815 0,12853202 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,057815 0,12837716 ! cGMP metabolic process GO:0046068 8 8 0,000 0,057815 0,12822267 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,057815 0,12806856 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,057815 0,12791482 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,057815 0,12776144 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,057815 0,12760843 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,057815 0,12745579 ! zinc ion transport GO:0006829 8 8 0,000 0,057815 0,12730352 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,057815 0,1271516 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,057815 0,12700005 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,057815 0,12684886 ! lipid localization GO:0010876 8 8 0,000 0,057815 0,12669803 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,057815 0,12654756 ! response to cAMP GO:0051591 8 8 0,000 0,057815 0,12639744 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,057815 0,12624768 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,057815 0,12609828 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,057815 0,12594922 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,057815 0,12580052 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,057815 0,12565217 ! sensory perception of taste GO:0050909 8 8 0,000 0,057815 0,12550417 ! organelle fusion GO:0048284 8 8 0,000 0,057815 0,12535652 ! pancreas development GO:0031016 8 8 0,000 0,057815 0,12520922 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,057815 0,12506226 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,057815 0,12491564 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,057815 0,12476937 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,057815 0,12462344 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,057815 0,12447785 ! sperm motility GO:0030317 8 8 0,000 0,057815 0,1243326 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,057815 0,1241877 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,057815 0,12404312 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,057815 0,12389889 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,057815 0,12375499 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,057815 0,12361142 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,057815 0,12346818 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,057815 0,12332528 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,057815 0,12318271 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,057815 0,12304046 ! fructose metabolic process GO:0006000 8 8 0,000 0,057815 0,12289855 ! mannose metabolic process GO:0006013 9 8 0,000 0,057815 0,12275696 ! NAD metabolic process GO:0019674 8 8 0,000 0,057815 0,1226157 ! sex determination GO:0007530 8 8 0,000 0,057815 0,12247476 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,057815 0,12233415 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,057815 0,12219386 ! response to fungus GO:0009620 8 8 0,000 0,057815 0,12205389 ! stem cell differentiation GO:0048863 8 8 0,000 0,057815 0,12191424 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,057815 0,12177491 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,057815 0,12163589 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,057815 0,1214972 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,057815 0,12135882 ! regulation of vasodilation GO:0042312 8 8 0,000 0,057815 0,12122075 ! vasoconstriction GO:0042310 8 8 0,000 0,057815 0,121083 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,057815 0,12094556 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,057815 0,12080844 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,057815 0,12067162 ! sensory perception of pain GO:0019233 8 8 0,000 0,057815 0,12053512 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,057815 0,12039892 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,057815 0,12026303 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,057815 0,12012744 ! tissue regeneration GO:0042246 8 8 0,000 0,057815 0,11999216 ! salivary gland development GO:0007431 8 8 0,000 0,057815 0,11985719 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,057815 0,11972252 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,057815 0,11958815 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,057815 0,11945408 ! water homeostasis GO:0030104 8 8 0,000 0,057815 0,11932032 ! cofactor transport GO:0051181 8 8 0,000 0,057815 0,11918685 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,057815 0,11905368 ! acid secretion GO:0046717 8 8 0,000 0,057815 0,11892081 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,057815 0,11878823 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,057815 0,11865595 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,057815 0,11852396 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,057815 0,11839227 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,057815 0,11826087 ! regulation of RNA stability GO:0043487 8 8 0,000 0,057815 0,11812976 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,057815 0,11799894 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,057815 0,11786841 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,057815 0,11773817 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,057815 0,11760821 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,057815 0,11747855 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,057815 0,11734917 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,057815 0,11722007 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,057815 0,11709126 ! developmental induction GO:0031128 8 8 0,000 0,057815 0,11696272 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,057815 0,11683448 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,057815 0,11670651 ! actin filament polymerization GO:0030041 9 8 0,000 0,057815 0,11657882 ! peptide hormone processing GO:0016486 8 8 0,000 0,057815 0,11645141 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,057815 0,11632428 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,057815 0,11619743 ! regulation of protein transport GO:0051223 53 53 1,000 0,05841909 0,11728364 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,06038533 0,12109919 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,06237428 0,12495195 ! extracellular structure organization GO:0043062 56 56 1,000 0,06438552 0,12884095 ! lactation GO:0007595 10 9 0,000 0,06480735 0,12954441 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06480735 0,12940406 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06480735 0,12926401 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06480735 0,12912426 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06480735 0,12898482 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06480735 0,12884568 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06480735 0,12870684 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,06480735 0,12856829 ! viral genome replication GO:0019079 9 9 0,000 0,06480735 0,12843005 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06480735 0,1282921 ! copper ion transport GO:0006825 9 9 0,000 0,06480735 0,12815445 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06480735 0,12801709 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06480735 0,12788003 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06480735 0,12774326 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06480735 0,12760678 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06480735 0,12747059 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06480735 0,1273347 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06480735 0,12719909 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06480735 0,12706377 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06480735 0,12692874 ! phospholipid efflux GO:0033700 9 9 0,000 0,06480735 0,126794 ! response to alkaloid GO:0043279 10 9 0,000 0,06480735 0,12665954 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06480735 0,12652537 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06480735 0,12639148 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,06480735 0,12625787 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06480735 0,12612455 ! response to ethanol GO:0045471 9 9 0,000 0,06480735 0,1259915 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,06480735 0,12585874 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06480735 0,12572626 ! methionine metabolic process GO:0006555 9 9 0,000 0,06480735 0,12559405 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06480735 0,12546213 ! response to osmotic stress GO:0006970 9 9 0,000 0,06480735 0,12533048 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06480735 0,1251991 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06480735 0,12506801 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06480735 0,12493718 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06480735 0,12480663 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06480735 0,12467635 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06480735 0,12454635 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06480735 0,12441661 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06480735 0,12428714 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,06480735 0,12415795 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06480735 0,12402902 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06480735 0,12390036 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06480735 0,12377196 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06480735 0,12364384 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06480735 0,12351597 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06480735 0,12338837 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,06480735 0,12326104 ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06480735 0,12313396 ! regulation of cellular pH GO:0030641 9 9 0,000 0,06480735 0,12300715 ! histone acetylation GO:0016573 9 9 0,000 0,06480735 0,1228806 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06480735 0,12275431 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06480735 0,12262828 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06480735 0,12250251 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06480735 0,12237699 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06480735 0,12225173 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,06480735 0,12212673 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06480735 0,12200199 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,06480735 0,12187749 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06480735 0,12175326 ! collagen catabolic process GO:0030574 9 9 0,000 0,06480735 0,12162927 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06480735 0,12150554 ! purine base metabolic process GO:0006144 9 9 0,000 0,06480735 0,12138206 ! gas transport GO:0015669 9 9 0,000 0,06480735 0,12125883 ! cholesterol efflux GO:0033344 9 9 0,000 0,06480735 0,12113585 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06480735 0,12101312 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06480735 0,12089063 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06480735 0,1207684 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06480735 0,12064641 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,06480735 0,12052467 ! defense response to virus GO:0051607 9 9 0,000 0,06480735 0,12040317 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06480735 0,12028192 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06480735 0,12016091 ! regulation of protein localization GO:0032880 58 57 1,000 0,06641862 0,12302465 ! dephosphorylation GO:0016311 60 59 1,000 0,07054875 0,13054352 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07174882 0,13263096 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07174882 0,13249807 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,07174882 0,13236544 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07174882 0,13223307 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,07174882 0,13210097 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07174882 0,13196913 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07174882 0,13183756 ! neuron maturation GO:0042551 10 10 0,000 0,07174882 0,13170625 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07174882 0,13157519 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07174882 0,1314444 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07174882 0,13131387 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07174882 0,1311836 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,07174882 0,13105359 ! hormone secretion GO:0046879 10 10 0,000 0,07174882 0,13092383 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07174882 0,13079433 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07174882 0,13066509 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07174882 0,1305361 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07174882 0,13040737 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07174882 0,13027889 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07174882 0,13015066 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07174882 0,13002268 ! glial cell development GO:0021782 10 10 0,000 0,07174882 0,12989496 ! phototransduction GO:0007602 11 10 0,000 0,07174882 0,12976749 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07174882 0,12964026 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07174882 0,12951329 ! fat cell differentiation GO:0045444 10 10 0,000 0,07174882 0,12938657 ! myoblast differentiation GO:0045445 10 10 0,000 0,07174882 0,12926009 ! centrosome cycle GO:0007098 10 10 0,000 0,07174882 0,12913386 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07174882 0,12900787 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07174882 0,12888213 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07174882 0,12875664 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07174882 0,12863139 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07174882 0,12850639 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07174882 0,12838162 ! plasma membrane organization GO:0007009 10 10 0,000 0,07174882 0,1282571 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07174882 0,12813282 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,07174882 0,12800878 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07174882 0,12788498 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07174882 0,12776142 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07174882 0,1276381 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07174882 0,12751501 ! exocrine system development GO:0035272 10 10 0,000 0,07174882 0,12739217 ! regulation of protein binding GO:0043393 11 10 0,000 0,07174882 0,12726956 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07174882 0,12714718 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07174882 0,12702504 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07174882 0,12690314 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07174882 0,12678147 ! protein export from nucleus GO:0006611 10 10 0,000 0,07174882 0,12666003 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07174882 0,12653882 ! cytolysis GO:0019835 10 10 0,000 0,07174882 0,12641785 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07174882 0,12629711 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07174882 0,12617659 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07174882 0,12605631 ! histone deacetylation GO:0016575 10 10 0,000 0,07174882 0,12593626 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07174882 0,12581643 ! gland morphogenesis GO:0022612 10 10 0,000 0,07174882 0,12569683 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07174882 0,12557746 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07174882 0,12545832 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07174882 0,1253394 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07174882 0,12522071 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07174882 0,12510224 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07174882 0,124984 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07174882 0,12486598 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07174882 0,12474818 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07174882 0,1246306 ! nerve development GO:0021675 10 10 0,000 0,07174882 0,12451325 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07174882 0,12439611 ! gut development GO:0048565 10 10 0,000 0,07174882 0,1242792 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07174882 0,12416251 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,07174882 0,12404603 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,07174882 0,12392978 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07174882 0,12381374 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07174882 0,12369791 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,07174882 0,12358231 ! protein stabilization GO:0050821 10 10 0,000 0,07174882 0,12346692 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,07264495 0,12489239 ! protein polymerization GO:0051258 65 60 1,000 0,07264495 0,12477599 ! cellular respiration GO:0045333 62 61 1,000 0,07476136 0,1282916 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,07476136 0,12817226 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! protein secretion GO:0009306 11 11 0,000 0,07863976 0,13469618 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07863976 0,13457111 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07863976 0,13444628 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07863976 0,13432167 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07863976 0,1341973 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07863976 0,13407316 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07863976 0,13394925 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07863976 0,13382556 ! skin development GO:0043588 11 11 0,000 0,07863976 0,13370211 ! signal complex assembly GO:0007172 11 11 0,000 0,07863976 0,13357888 ! microtubule-based transport GO:0010970 11 11 0,000 0,07863976 0,13345588 ! endothelial cell migration GO:0043542 11 11 0,000 0,07863976 0,13333311 ! peroxisomal transport GO:0043574 11 11 0,000 0,07863976 0,13321056 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07863976 0,13308823 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,07863976 0,13296613 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,07863976 0,13284426 GO:0032388|positive regulation of intracellular transport, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07863976 0,13272261 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07863976 0,13260118 ! T cell proliferation GO:0042098 11 11 0,000 0,07863976 0,13247997 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07863976 0,13235898 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07863976 0,13223822 ! spinal cord development GO:0021510 11 11 0,000 0,07863976 0,13211767 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07863976 0,13199735 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07863976 0,13187724 ! cellular response to starvation GO:0009267 11 11 0,000 0,07863976 0,13175735 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,07863976 0,13163768 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07863976 0,13151823 ! digestive system process GO:0022600 11 11 0,000 0,07863976 0,13139899 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07863976 0,13127997 ! fucose metabolic process GO:0006004 11 11 0,000 0,07863976 0,13116116 ! membrane budding GO:0006900 11 11 0,000 0,07863976 0,13104257 ! monoamine transport GO:0015844 11 11 0,000 0,07863976 0,1309242 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07863976 0,13080603 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07863976 0,13068809 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07863976 0,13057035 ! body fluid secretion GO:0007589 11 11 0,000 0,07863976 0,13045282 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,07863976 0,13033551 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07863976 0,13021841 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07863976 0,13010151 ! interaction with host GO:0051701 11 11 0,000 0,07863976 0,12998483 ! membrane depolarization GO:0051899 11 11 0,000 0,07863976 0,12986836 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07863976 0,12975209 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07863976 0,12963603 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,07863976 0,12952018 ! oogenesis GO:0048477 11 11 0,000 0,07863976 0,12940454 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07863976 0,12928911 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07863976 0,12917387 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,07863976 0,12905885 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,07863976 0,12894403 ! muscle maintenance GO:0046716 12 11 0,000 0,07863976 0,12882941 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07863976 0,128715 ! steroid catabolic process GO:0006706 11 11 0,000 0,07863976 0,12860079 ! endocrine process GO:0050886 11 11 0,000 0,07863976 0,12848678 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07863976 0,12837297 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07863976 0,12825937 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07863976 0,12814597 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07863976 0,12803276 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,07905321 0,1285923 ! angiogenesis GO:0001525 65 64 1,000 0,08122787 0,1320132 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,08122787 0,13189689 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,08548055 0,13868016 ! translational initiation GO:0006413 12 12 0,000 0,08548055 0,13855819 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,08548055 0,13843643 ! initiation of viral infection GO:0019059 12 12 0,000 0,08548055 0,13831489 ! iron ion transport GO:0006826 13 12 0,000 0,08548055 0,13819356 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08548055 0,13807244 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08548055 0,13795154 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08548055 0,13783085 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08548055 0,13771037 ! collagen metabolic process GO:0032963 12 12 0,000 0,08548055 0,1375901 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08548055 0,13747003 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08548055 0,13735018 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08548055 0,13723054 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08548055 0,1371111 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08548055 0,13699188 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08548055 0,13687286 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08548055 0,13675404 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,08548055 0,13663544 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08548055 0,13651704 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08548055 0,13639884 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08548055 0,13628085 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,08548055 0,13616306 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08548055 0,13604547 ! vacuolar transport GO:0007034 12 12 0,000 0,08548055 0,13592809 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08548055 0,13581091 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08548055 0,13569394 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08548055 0,13557716 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08548055 0,13546058 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08548055 0,13534421 ! male gonad development GO:0008584 12 12 0,000 0,08548055 0,13522803 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08548055 0,13511206 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08548055 0,13499628 ! renal system process GO:0003014 12 12 0,000 0,08548055 0,1348807 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08548055 0,13476532 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08548055 0,13465014 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,08548055 0,13453515 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08548055 0,13442036 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08548055 0,13430576 ! somitogenesis GO:0001756 13 12 0,000 0,08548055 0,13419136 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08548055 0,13407716 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08548055 0,13396315 ! detection of light stimulus GO:0009583 13 12 0,000 0,08548055 0,13384933 ! synaptogenesis GO:0007416 12 12 0,000 0,08548055 0,1337357 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08548055 0,13362227 ! hormone transport GO:0009914 12 12 0,000 0,08548055 0,13350903 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08548055 0,13339599 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08548055 0,13328313 ! spermatid differentiation GO:0048515 13 12 0,000 0,08548055 0,13317046 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08548055 0,13305799 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08548055 0,1329457 ! neural tube closure GO:0001843 13 12 0,000 0,08548055 0,13283361 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08548055 0,1327217 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,08548055 0,13260998 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,08563272 0,13273432 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,08786215 0,13607558 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,08786215 0,13596133 ! regulation of cell size GO:0008361 68 68 1,000 0,09010908 0,13932133 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,09227154 0,14254522 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,09227154 0,14242583 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,09227154 0,14230665 ! phenol metabolic process GO:0018958 13 13 0,000 0,09227154 0,14218766 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,09227154 0,14206888 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,09227154 0,14195029 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,09227154 0,1418319 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,09227154 0,1417137 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,09227154 0,14159571 ! regeneration GO:0031099 13 13 0,000 0,09227154 0,14147791 ! keratinization GO:0031424 13 13 0,000 0,09227154 0,1413603 ! post-embryonic development GO:0009791 14 13 0,000 0,09227154 0,1412429 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,09227154 0,14112568 ! patterning of blood vessels GO:0001569 13 13 0,000 0,09227154 0,14100866 ! regulation of innate immune response GO:0045088 13 13 0,000 0,09227154 0,14089184 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,09227154 0,1407752 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,09227154 0,14065876 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,09227154 0,14054252 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,09227154 0,14042646 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,09227154 0,1403106 ! autophagy GO:0006914 13 13 0,000 0,09227154 0,14019493 ! receptor metabolic process GO:0043112 14 13 0,000 0,09227154 0,14007944 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,09227154 0,13996415 ! ureteric bud development GO:0001657 13 13 0,000 0,09227154 0,13984905 ! cell aging GO:0007569 13 13 0,000 0,09227154 0,13973414 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,09227154 0,13961941 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,09227154 0,13950488 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,09227154 0,13939053 ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,09227154 0,13927637 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,09227154 0,13916239 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,09227154 0,13904861 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,09227154 0,138935 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,09227154 0,13882159 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,09227154 0,13870836 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,09227154 0,13859531 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,09227154 0,13848245 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,09227154 0,13836977 ! vasodilation GO:0042311 14 13 0,000 0,09227154 0,13825727 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,09227154 0,13814496 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,09227154 0,13803283 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,09227154 0,13792088 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,09227154 0,13780911 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,09227154 0,13769753 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,09227154 0,13758612 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,09227154 0,1374749 ! immunoglobulin production GO:0002377 13 13 0,000 0,09227154 0,13736385 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,09227154 0,13725298 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,09227154 0,1371423 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,09227154 0,13703179 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,09227154 0,13692145 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,09227154 0,1368113 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,09227154 0,13670132 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,09227154 0,13659152 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,09227154 0,1364819 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,09227154 0,13637245 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,09227154 0,13626318 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,09227154 0,13615408 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,09227154 0,13604516 ! telomere organization GO:0032200 13 13 0,000 0,09227154 0,13593641 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,09227154 0,13582783 ! regulation of amine transport GO:0051952 13 13 0,000 0,09227154 0,13571943 ! tissue homeostasis GO:0001894 13 13 0,000 0,09227154 0,1356112 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,09227154 0,13550314 ! protein tetramerization GO:0051262 13 13 0,000 0,09227154 0,13539526 ! regulation of translation GO:0006417 69 69 1,000 0,09237314 0,13543651 ! sensory perception of sound GO:0007605 71 69 1,000 0,09237314 0,13532885 GO:0050954|sensory perception of mechanical stimulus, ! positive regulation of transport GO:0051050 71 70 1,000 0,09465397 0,13856018 ! growth GO:0040007 70 70 1,000 0,09465397 0,13845021 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,09465397 0,13834041 GO:0016053|organic acid biosynthetic process, ! regulation of cell migration GO:0030334 71 71 1,000 0,0969512 0,14158563 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,0969512 0,14147353 GO:0006874|cellular calcium ion homeostasis, ! neuron fate commitment GO:0048663 14 14 0,000 0,09901308 0,14436796 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09901308 0,14425384 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09901308 0,14413989 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09901308 0,14402613 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09901308 0,14391254 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,09901308 0,14379914 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09901308 0,14368591 ! protein amino acid acylation GO:0043543 14 14 0,000 0,09901308 0,14357286 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09901308 0,14345999 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09901308 0,14334729 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09901308 0,14323477 ! vesicle docking GO:0048278 14 14 0,000 0,09901308 0,14312243 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09901308 0,14301027 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09901308 0,14289828 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09901308 0,14278647 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09901308 0,14267483 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09901308 0,14256336 ! hair cycle GO:0042633 14 14 0,000 0,09901308 0,14245207 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09901308 0,14234095 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09901308 0,14223001 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09901308 0,14211924 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,09901308 0,14200864 ! lysosome organization GO:0007040 14 14 0,000 0,09901308 0,14189821 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09901308 0,14178796 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09901308 0,14167788 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,09901308 0,14156796 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,09901308 0,14145822 ! primary neural tube formation GO:0014020 15 14 0,000 0,09901308 0,14134865 ! peptide cross-linking GO:0018149 14 14 0,000 0,09901308 0,14123924 ! regulation of behavior GO:0050795 14 14 0,000 0,09901308 0,14113001 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09901308 0,14102095 ! base-excision repair GO:0006284 14 14 0,000 0,09901308 0,14091205 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,09901308 0,14080332 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09901308 0,14069476 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09901308 0,14058637 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09901308 0,14047814 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,09901308 0,14037008 ! collagen fibril organization GO:0030199 14 14 0,000 0,09901308 0,14026219 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09901308 0,14015446 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,09901308 0,14004689 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,09901308 0,1399395 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09901308 0,13983226 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09901308 0,13972519 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,09901308 0,13961829 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09901308 0,13951155 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09901308 0,13940497 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09901308 0,13929855 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,1039378 0,14611546 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,10570552 0,14848726 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10570552 0,14837417 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10570552 0,14826125 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,10570552 0,1481485 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10570552 0,14803593 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10570552 0,14792352 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10570552 0,14781129 ! response to vitamin GO:0033273 15 15 0,000 0,10570552 0,14769923 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10570552 0,14758733 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10570552 0,14747561 ! ovarian follicle development GO:0001541 15 15 0,000 0,10570552 0,14736406 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10570552 0,14725267 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10570552 0,14714145 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10570552 0,1470304 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10570552 0,14691952 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,10570552 0,1468088 ! heme metabolic process GO:0042168 15 15 0,000 0,10570552 0,14669825 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10570552 0,14658787 ! chromosome condensation GO:0030261 15 15 0,000 0,10570552 0,14647765 ! response to starvation GO:0042594 15 15 0,000 0,10570552 0,1463676 ! response to ionizing radiation GO:0010212 16 15 0,000 0,10570552 0,14625772 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10570552 0,146148 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10570552 0,14603844 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10570552 0,14592905 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,10570552 0,14581982 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10570552 0,14571076 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10570552 0,14560185 ! phospholipid transport GO:0015914 15 15 0,000 0,10570552 0,14549311 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10570552 0,14538454 ! glutathione metabolic process GO:0006749 16 15 0,000 0,10570552 0,14527612 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10570552 0,14516787 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10570552 0,14505978 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10570552 0,14495185 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,10570552 0,14484407 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10570552 0,14473646 ! protein homooligomerization GO:0051260 15 15 0,000 0,10570552 0,14462901 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10570552 0,14452172 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,11105946 0,15172913 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,11234923 0,1533775 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,11234923 0,15326397 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,11234923 0,15315061 ! circadian rhythm GO:0007623 16 16 0,000 0,11234923 0,15303742 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,11234923 0,15292439 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,11234923 0,15281153 ! vacuole organization GO:0007033 16 16 0,000 0,11234923 0,15269884 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,11234923 0,15258631 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,11234923 0,15247395 ! vesicle targeting GO:0006903 17 16 0,000 0,11234923 0,15236175 ! segmentation GO:0035282 17 16 0,000 0,11234923 0,15224972 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,11234923 0,15213786 ! iron ion homeostasis GO:0055072 16 16 0,000 0,11234923 0,15202616 ! positive regulation of cell development GO:0010720 16 16 0,000 0,11234923 0,15191462 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,11234923 0,15180324 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,11234923 0,15169203 ! cell fate specification GO:0001708 16 16 0,000 0,11234923 0,15158098 ! pentose metabolic process GO:0019321 16 16 0,000 0,11234923 0,1514701 ! fatty acid transport GO:0015908 16 16 0,000 0,11234923 0,15135937 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,11234923 0,15124881 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,11234923 0,15113841 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,11234923 0,15102817 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,11234923 0,15091809 ! polyol metabolic process GO:0019751 16 16 0,000 0,11234923 0,15080818 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,11234923 0,15069842 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,11234923 0,15058882 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,11234923 0,15047938 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,11234923 0,1503701 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,11234923 0,15026098 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,11234923 0,15015201 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,11234923 0,15004321 ! regulation of coagulation GO:0050818 17 16 0,000 0,11234923 0,14993456 ! microtubule-based movement GO:0007018 82 78 1,000 0,11346179 0,15130975 ! metal ion homeostasis GO:0055065 78 78 1,000 0,11346179 0,15120035 ! regulation of locomotion GO:0040012 79 79 1,000 0,11587778 0,15430835 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,11894453 0,15827782 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,11894453 0,15816362 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,11894453 0,15804959 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,11894453 0,15793572 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,11894453 0,15782201 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,11894453 0,15770847 ! sensory perception of smell GO:0007608 17 17 0,000 0,11894453 0,15759509 ! tissue remodeling GO:0048771 17 17 0,000 0,11894453 0,15748188 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,11894453 0,15736883 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,11894453 0,15725594 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,11894453 0,15714321 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,11894453 0,15703064 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,11894453 0,15691824 ! neural crest cell development GO:0014032 19 17 0,000 0,11894453 0,15680599 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,11894453 0,15669391 ! negative regulation of cell development GO:0010721 18 17 0,000 0,11894453 0,15658198 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,11894453 0,15647022 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,11894453 0,15635861 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,11894453 0,15624717 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,11894453 0,15613588 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,11894453 0,15602475 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,11894453 0,15591378 ! adult locomotory behavior GO:0008344 17 17 0,000 0,11894453 0,15580297 ! embryonic organ development GO:0048568 17 17 0,000 0,11894453 0,15569231 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,11894453 0,15558181 ! liver development GO:0001889 17 17 0,000 0,11894453 0,15547147 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12549179 0,16391309 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,12549179 0,16379701 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,12549179 0,16368108 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12549179 0,16356533 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12549179 0,16344973 ! membrane docking GO:0022406 18 18 0,000 0,12549179 0,1633343 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,12549179 0,16321903 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,12549179 0,16310393 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,12549179 0,16298899 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12549179 0,16287421 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,12549179 0,16275959 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,12549179 0,16264513 ! striated muscle contraction GO:0006941 18 18 0,000 0,12549179 0,16253083 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12549179 0,16241669 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,12549179 0,16230272 ! ceramide metabolic process GO:0006672 18 18 0,000 0,12549179 0,1621889 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,12549179 0,16207524 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12549179 0,16196174 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12549179 0,16184841 ! B cell differentiation GO:0030183 18 18 0,000 0,12549179 0,16173523 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,12549179 0,1616222 ! BMP signaling pathway GO:0030509 18 18 0,000 0,12549179 0,16150934 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,12549179 0,16139663 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12549179 0,16128408 ! regulation of cellular localization GO:0060341 86 85 1,000 0,1306429 0,16778737 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,1306429 0,16767052 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,13199134 0,16928326 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,13199134 0,16916554 GO:0006956|complement activation, ! regulation of pH GO:0006885 19 19 0,000 0,13199134 0,16904798 ! feeding behavior GO:0007631 19 19 0,000 0,13199134 0,16893059 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,13199134 0,16881335 ! peroxisome organization GO:0007031 19 19 0,000 0,13199134 0,16869629 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,13199134 0,16857938 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,13199134 0,16846263 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,13199134 0,16834605 ! metanephros development GO:0001656 19 19 0,000 0,13199134 0,16822963 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,13199134 0,16811337 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,13199134 0,16799727 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,13199134 0,16788133 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,13199134 0,16776555 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,13199134 0,16764993 ! regulation of protein stability GO:0031647 19 19 0,000 0,13199134 0,16753447 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,13199134 0,16741916 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,13199134 0,16730402 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,13199134 0,16718903 ! eye morphogenesis GO:0048592 19 19 0,000 0,13199134 0,16707421 ! regulation of cell shape GO:0008360 21 19 0,000 0,13199134 0,16695954 ! response to heat GO:0009408 19 19 0,000 0,13199134 0,16684502 ! vesicle localization GO:0051648 20 19 0,000 0,13199134 0,16673067 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,13314571 0,16807367 ! regulation of muscle development GO:0048634 21 20 0,000 0,13844353 0,17464163 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,13844353 0,17452218 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,13844353 0,17440289 ! negative regulation of binding GO:0051100 21 20 0,000 0,13844353 0,17428376 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13844353 0,17416479 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,13844353 0,17404599 ! phagocytosis GO:0006909 21 20 0,000 0,13844353 0,17392735 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13844353 0,17380887 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13844353 0,17369055 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13844353 0,1735724 ! chromatin remodeling GO:0006338 20 20 0,000 0,13844353 0,1734544 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13844353 0,17333656 ! female gamete generation GO:0007292 20 20 0,000 0,13844353 0,17321889 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,13844353 0,17310137 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13844353 0,17298401 ! RNA modification GO:0009451 20 20 0,000 0,13844353 0,17286682 ! chemotaxis GO:0006935 90 89 1,000 0,14072006 0,17559044 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,14072006 0,17547164 ! mRNA catabolic process GO:0006402 21 21 0,000 0,14484868 0,18049772 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,14484868 0,18037576 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,14484868 0,18025397 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,14484868 0,18013234 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,14484868 0,18001087 ! ear morphogenesis GO:0042471 21 21 0,000 0,14484868 0,17988957 ! organic anion transport GO:0015711 21 21 0,000 0,14484868 0,17976844 ! cholesterol transport GO:0030301 21 21 0,000 0,14484868 0,17964746 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,14484868 0,17952665 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,14484868 0,179406 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,14484868 0,17928551 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,14484868 0,17916519 ! regulation of proteolysis GO:0030162 21 21 0,000 0,14484868 0,17904502 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,14484868 0,17892502 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,14484868 0,17880518 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,14582166 0,17988576 ! DNA replication GO:0006260 91 91 1,000 0,14582166 0,17976544 ! visual perception GO:0007601 93 92 1,000 0,14838722 0,18280592 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 1,000 0,14838722 0,1826838 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,14838722 0,18256185 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,15120715 0,18590712 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,15120715 0,18578319 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,15120715 0,18565941 ! regulation of ion transport GO:0043269 22 22 0,000 0,15120715 0,1855358 ! odontogenesis GO:0042476 22 22 0,000 0,15120715 0,18541236 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,15120715 0,18528908 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,15120715 0,18516597 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,15120715 0,18504301 ! ovulation cycle process GO:0022602 22 22 0,000 0,15120715 0,18492022 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,15120715 0,1847976 ! cell chemotaxis GO:0060326 23 22 0,000 0,15120715 0,18467514 GO:0030595|leukocyte chemotaxis, ! male sex differentiation GO:0046661 22 22 0,000 0,15120715 0,18455283 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,15120715 0,18443069 ! biopolymer methylation GO:0043414 22 22 0,000 0,15120715 0,18430872 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,15120715 0,1841869 ! detection of external stimulus GO:0009581 23 22 0,000 0,15120715 0,18406524 ! neuron migration GO:0001764 22 22 0,000 0,15120715 0,18394375 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,15120715 0,18382241 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,15120715 0,18370124 ! cytokine production GO:0001816 22 22 0,000 0,15120715 0,18358022 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,15120715 0,18345937 ! cofactor metabolic process GO:0051186 95 94 1,000 0,15354648 0,1861751 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,15751926 0,19086653 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,15751926 0,19074113 ! viral infectious cycle GO:0019058 23 23 0,000 0,15751926 0,19061589 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,15751926 0,19049081 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,15751926 0,1903659 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,15751926 0,19024115 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,15751926 0,19011656 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,15751926 0,18999214 ! endocrine system development GO:0035270 23 23 0,000 0,15751926 0,18986788 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,15751926 0,18974379 ! positive regulation of growth GO:0045927 23 23 0,000 0,15751926 0,18961985 ! female gonad development GO:0008585 23 23 0,000 0,15751926 0,18949608 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,15751926 0,18937247 ! lipid homeostasis GO:0055088 23 23 0,000 0,15751926 0,18924902 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,15751926 0,18912573 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,15751926 0,1890026 ! cell projection assembly GO:0030031 25 23 0,000 0,15751926 0,18887963 ! mitochondrial transport GO:0006839 24 24 0,000 0,16378534 0,19626553 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,16378534 0,196138 ! glucose homeostasis GO:0042593 24 24 0,000 0,16378534 0,19601064 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,16378534 0,19588344 ! T cell differentiation GO:0030217 24 24 0,000 0,16378534 0,19575641 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,16378534 0,19562954 ! ovulation cycle GO:0042698 24 24 0,000 0,16378534 0,19550284 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,16378534 0,1953763 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,16378534 0,19524992 ! glucan metabolic process GO:0044042 25 24 0,000 0,16378534 0,19512371 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! endocytosis GO:0006897 99 98 1,000 0,16397 0,19521751 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,16397 0,19509148 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,16397 0,19496562 ! regulation of system process GO:0044057 98 98 1,000 0,16397 0,19483991 ! response to hormone stimulus GO:0009725 102 100 1,000 0,16923008 0,20096072 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,17000572 0,2017518 ! negative regulation of secretion GO:0051048 26 25 0,000 0,17000572 0,20162197 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,17000572 0,20149231 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,17000572 0,20136282 ! endosome transport GO:0016197 25 25 0,000 0,17000572 0,20123349 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,17000572 0,20110433 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,17000572 0,20097534 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,17000572 0,2008465 ! excretion GO:0007588 25 25 0,000 0,17000572 0,20071784 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,17000572 0,20058934 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,17000572 0,200461 ! gastrulation GO:0007369 25 25 0,000 0,17000572 0,20033283 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,17000572 0,20020482 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,17000572 0,20007698 ! positive regulation of binding GO:0051099 27 26 0,000 0,17618074 0,20721193 ! positive regulation of defense response GO:0031349 26 26 0,000 0,17618074 0,20707978 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,17618074 0,2069478 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,17618074 0,20681598 ! cellular defense response GO:0006968 26 26 0,000 0,17618074 0,20668434 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,17618074 0,20655286 ! double-strand break repair GO:0006302 27 26 0,000 0,17618074 0,20642155 ! regulation of protein secretion GO:0050708 26 26 0,000 0,17618074 0,2062904 ! germ cell development GO:0007281 27 26 0,000 0,17618074 0,20615943 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,17618074 0,20602861 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,17618074 0,20589797 ! chloride transport GO:0006821 27 27 0,000 0,1823107 0,21292688 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,1823107 0,21279203 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,1823107 0,21265735 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,1823107 0,21252285 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,1823107 0,21238851 ! peptide metabolic process GO:0006518 29 27 0,000 0,1823107 0,21225434 ! activation of caspase activity GO:0006919 27 27 0,000 0,1823107 0,21212034 ! mesenchymal cell development GO:0014031 29 27 0,000 0,1823107 0,21198651 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,1823107 0,21185285 ! defense response to bacterium GO:0042742 27 27 0,000 0,1823107 0,21171936 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,1823107 0,21158603 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,1823107 0,21145288 ! cell growth GO:0016049 27 27 0,000 0,1823107 0,21131989 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,18839594 0,21823615 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,18839594 0,21809907 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,18839594 0,21796216 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,18839594 0,21782542 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,18839594 0,21768885 ! histone modification GO:0016570 28 28 0,000 0,18839594 0,21755246 ! cartilage development GO:0051216 29 28 0,000 0,18839594 0,21741623 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,19443678 0,22424717 ! viral reproductive process GO:0022415 29 29 0,000 0,19443678 0,22410693 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,19443678 0,22396686 ! leukocyte migration GO:0050900 30 29 0,000 0,19443678 0,22382697 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,19443678 0,22368725 ! antigen processing and presentation GO:0019882 29 29 0,000 0,19443678 0,22354771 ! tRNA processing GO:0008033 29 29 0,000 0,19443678 0,22340834 ! adult behavior GO:0030534 30 29 0,000 0,19443678 0,22326915 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,19443678 0,22313012 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,19443678 0,22299128 ! transition metal ion transport GO:0000041 31 30 0,000 0,20043353 0,22972574 ! RNA catabolic process GO:0006401 30 30 0,000 0,20043353 0,22958296 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,20043353 0,22944036 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,20043353 0,22929794 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,20043353 0,2291557 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,20043353 0,22901363 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,20043353 0,22887174 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,20043353 0,22873002 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,20043353 0,22858848 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,20043353 0,22844712 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,20043353 0,22830593 ! response to temperature stimulus GO:0009266 30 30 0,000 0,20043353 0,22816491 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,20043353 0,22802407 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,20043353 0,2278834 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,20043353 0,2277429 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,20043353 0,22760258 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,20043353 0,22746243 ! regulation of translational initiation GO:0006446 31 31 0,000 0,2063865 0,23407405 ! B cell activation GO:0042113 31 31 0,000 0,2063865 0,23393009 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,2063865 0,23378631 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,2063865 0,2336427 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,2063865 0,23349928 ! ion transmembrane transport GO:0034220 31 31 0,000 0,2063865 0,23335603 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,2063865 0,23321295 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,2063865 0,23307005 ! digestion GO:0007586 31 31 0,000 0,2063865 0,23292733 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,2063865 0,23278478 ! regulation of heart contraction GO:0008016 31 31 0,000 0,2063865 0,2326424 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,2063865 0,2325002 ! camera-type eye development GO:0043010 31 31 0,000 0,2063865 0,23235817 ! extracellular matrix organization GO:0030198 31 31 0,000 0,2063865 0,23221631 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,2063865 0,23207463 ! cell redox homeostasis GO:0045454 32 32 0,000 0,21229602 0,23857412 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,21229602 0,23842874 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,21229602 0,23828354 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,21229602 0,23813851 ! nuclear export GO:0051168 32 32 0,000 0,21229602 0,23799365 ! kidney development GO:0001822 32 32 0,000 0,21229602 0,23784898 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,21229602 0,23770447 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,21816239 0,24412464 ! amino acid transport GO:0006865 33 33 0,000 0,21816239 0,24397651 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,21816239 0,24382855 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,21816239 0,24368078 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,21816239 0,24353318 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,21816239 0,24338577 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,21816239 0,24323853 ! response to metal ion GO:0010038 34 34 0,000 0,22398592 0,24958044 ! ear development GO:0043583 34 34 0,000 0,22398592 0,24942964 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,22398592 0,24927902 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,22398592 0,24912858 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,22398592 0,24897832 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,22398592 0,24882824 ! secondary metabolic process GO:0019748 34 34 0,000 0,22398592 0,24867835 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,22398592 0,24852863 ! viral reproduction GO:0016032 34 34 0,000 0,22398592 0,24837909 ! detection of stimulus GO:0051606 36 34 0,000 0,22398592 0,24822974 ! acute inflammatory response GO:0002526 35 35 0,000 0,22976692 0,25448343 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,22976692 0,25433059 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,22976692 0,25417793 ! inorganic anion transport GO:0015698 35 35 0,000 0,22976692 0,25402546 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,22976692 0,25387316 ! regulation of immune effector process GO:0002697 35 35 0,000 0,22976692 0,25372105 ! hydrogen transport GO:0006818 36 36 0,000 0,23550569 0,25990239 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,23550569 0,25974685 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,23550569 0,2595915 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,23550569 0,25943634 ! positive regulation of cell migration GO:0030335 36 36 0,000 0,23550569 0,25928136 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,23550569 0,25912656 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,23550569 0,25897195 ! gonad development GO:0008406 36 36 0,000 0,23550569 0,25881752 ! regulation of lipase activity GO:0060191 36 36 0,000 0,23550569 0,25866328 ! activation of immune response GO:0002253 36 36 0,000 0,23550569 0,25850923 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,24120254 0,26460493 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,24120254 0,26444752 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 0,000 0,24120254 0,26429029 ! lung development GO:0030324 38 37 0,000 0,24120254 0,26413326 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,24120254 0,26397641 ! eye development GO:0001654 37 37 0,000 0,24120254 0,26381975 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,24120254 0,26366327 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! adaptive immune response GO:0002250 37 37 0,000 0,24120254 0,26350698 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,24685776 0,26952538 ! neurotransmitter transport GO:0006836 40 38 0,000 0,24685776 0,26936581 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,24685776 0,26920642 ! exocytosis GO:0006887 40 38 0,000 0,24685776 0,26904722 ! urogenital system development GO:0001655 38 38 0,000 0,24685776 0,26888821 ! RNA elongation GO:0006354 38 38 0,000 0,24685776 0,26872938 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,24685776 0,26857075 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,25247165 0,27451637 ! activation of MAPK activity GO:0000187 39 39 0,000 0,25247165 0,27435451 ! respiratory tube development GO:0030323 40 39 0,000 0,25247165 0,27419284 ! response to unfolded protein GO:0006986 39 39 0,000 0,25247165 0,27403136 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,25247165 0,27387007 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,25247165 0,27370897 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,25247165 0,27354806 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,25247165 0,27338734 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,25247165 0,27322681 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,25247165 0,27306646 ! respiratory system development GO:0060541 40 39 0,000 0,25247165 0,2729063 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,25247165 0,27274634 ! protein oligomerization GO:0051259 39 39 0,000 0,25247165 0,27258656 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,25804451 0,2784403 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,26357664 0,28424326 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,26357664 0,28407704 ! regulation of caspase activity GO:0043281 41 41 0,000 0,26357664 0,28391101 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,26357664 0,28374517 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,26357664 0,28357953 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,26357664 0,28341408 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,26906831 0,28915038 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,26906831 0,28898188 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,26906831 0,28881357 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,26906831 0,28864546 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,26906831 0,28847755 ! protein ubiquitination GO:0016567 43 42 0,000 0,26906831 0,28830983 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,26906831 0,2881423 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,26906831 0,28797497 ! reproductive structure development GO:0048608 43 43 0,000 0,27451984 0,29363904 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,27451984 0,29346871 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,27451984 0,29329859 ! humoral immune response GO:0006959 44 44 0,000 0,27993149 0,29890715 ! mRNA transport GO:0051028 44 44 0,000 0,27993149 0,29873407 ! vitamin metabolic process GO:0006766 44 44 0,000 0,27993149 0,29856119 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,27993149 0,29838851 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,28530357 0,303939 ! regulation of DNA binding GO:0051101 47 45 0,000 0,28530357 0,30376342 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,28530357 0,30358803 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,28530357 0,30341285 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,29063634 0,30890587 ! tube morphogenesis GO:0035239 47 46 0,000 0,29063634 0,30872783 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,29063634 0,30854999 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,29063634 0,30837235 ! regulation of blood pressure GO:0008217 48 47 0,000 0,2959301 0,3138085 ! sex differentiation GO:0007548 47 47 0,000 0,2959301 0,31362805 ! amine transport GO:0015837 47 47 0,000 0,2959301 0,3134478 ! rhythmic process GO:0048511 47 47 0,000 0,2959301 0,31326776 ! regulation of catabolic process GO:0009894 48 47 0,000 0,2959301 0,31308793 ! calcium ion transport GO:0006816 48 48 0,000 0,30118512 0,31846482 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,30118512 0,31828221 ! DNA recombination GO:0006310 48 48 0,000 0,30118512 0,31809982 ! leukocyte differentiation GO:0002521 50 49 0,000 0,30640168 0,323424 ! divalent metal ion transport GO:0070838 49 49 0,000 0,30640168 0,32323887 ! response to nutrient GO:0007584 49 49 0,000 0,30640168 0,32305395 ! response to bacterium GO:0009617 50 49 0,000 0,30640168 0,32286924 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,30640168 0,32268475 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,30640168 0,32250046 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,31158006 0,32776373 ! chromatin assembly GO:0031497 50 50 0,000 0,31158006 0,32757676 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,31158006 0,32739 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,31158006 0,32720345 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,31158006 0,32701712 ! transcription initiation GO:0006352 50 50 0,000 0,31158006 0,326831 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,31158006 0,32664509 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,31158006 0,32645939 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,31672054 0,33165679 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,31672054 0,33146845 ! positive regulation of immune response GO:0050778 51 51 0,000 0,31672054 0,33128033 ! rRNA metabolic process GO:0016072 51 51 0,000 0,31672054 0,33109243 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,31672054 0,33090473 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,31672054 0,33071725 ! RNA localization GO:0006403 52 52 0,000 0,32182337 0,33585531 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,32182337 0,33566524 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,32182337 0,33547538 ! sodium ion transport GO:0006814 53 53 0,000 0,32688884 0,3405631 ! tRNA metabolic process GO:0006399 53 53 0,000 0,32688884 0,34037069 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,32688884 0,3401785 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,32688884 0,33998653 ! response to virus GO:0009615 54 54 0,000 0,3319172 0,34502166 ! hormone metabolic process GO:0042445 55 54 0,000 0,3319172 0,34482718 ! sulfur metabolic process GO:0006790 55 54 0,000 0,3319172 0,34463291 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,3319172 0,34443886 ! nucleosome organization GO:0034728 55 55 0,000 0,33690874 0,34942195 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,33690874 0,34922543 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,33690874 0,34902912 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,34186371 0,35396338 ! reproductive developmental process GO:0003006 56 56 0,000 0,34186371 0,35376463 ! regulation of nervous system development GO:0051960 57 56 0,000 0,34186371 0,35356611 ! regulation of binding GO:0051098 60 57 0,000 0,34678237 0,358452 ! ATP metabolic process GO:0046034 57 57 0,000 0,34678237 0,35825107 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,34678237 0,35805037 ! innate immune response GO:0045087 58 58 0,000 0,35166499 0,36288834 ! carboxylic acid transport GO:0046942 59 59 0,000 0,35651182 0,36768399 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,35651182 0,36747835 ! sterol metabolic process GO:0016125 59 59 0,000 0,35651182 0,36727294 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,35651182 0,36706776 ! immune effector process GO:0002252 59 59 0,000 0,35651182 0,3668628 ! potassium ion transport GO:0006813 60 60 0,000 0,36132312 0,37160631 ! lipid transport GO:0006869 62 62 0,000 0,37084016 0,38118149 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,37084016 0,38096902 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,37084016 0,38075678 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,37084016 0,38054478 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,37084016 0,38033301 ! regulation of secretion GO:0051046 65 63 0,000 0,3755464 0,38494551 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,3755464 0,38473153 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,3755464 0,38451779 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,38021813 0,38908496 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,38021813 0,38886904 ! anion transport GO:0006820 65 65 0,000 0,38485558 0,39339369 ! regulation of hormone levels GO:0010817 66 65 0,000 0,38485558 0,39317563 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,38945901 0,39765814 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,38945901 0,39743796 ! DNA packaging GO:0006323 66 66 0,000 0,38945901 0,39721801 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,38945901 0,39699831 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,39402866 0,40143439 ! muscle contraction GO:0006936 67 67 0,000 0,39402866 0,4012126 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,39856477 0,40560733 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,39856477 0,40538348 ! regionalization GO:0003002 70 69 0,000 0,40306759 0,40973721 ! response to nutrient levels GO:0031667 69 69 0,000 0,40306759 0,40951134 ! translational elongation GO:0006414 71 71 0,000 0,41197429 0,41832982 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,41197429 0,41809946 ! ribosome biogenesis GO:0042254 71 71 0,000 0,41197429 0,41786936 ! secretion by cell GO:0032940 75 72 0,000 0,41637866 0,42210444 ! muscle system process GO:0003012 72 72 0,000 0,41637866 0,42187238 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,41637866 0,42164059 ! sensory organ development GO:0007423 72 72 0,000 0,41637866 0,42140904 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,41637866 0,42117775 ! regulation of cytokine production GO:0001817 72 72 0,000 0,41637866 0,42094672 ! electron transport chain GO:0022900 75 74 0,000 0,42509058 0,4295186 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,4293986 0,43363376 ! response to oxidative stress GO:0006979 76 75 0,000 0,4293986 0,43339628 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,4293986 0,43315907 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,43367496 0,43723356 ! regulation of immune response GO:0050776 78 78 0,000 0,44213364 0,44551794 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,45046843 0,45366848 ! MAPKKK cascade GO:0000165 82 81 0,000 0,45458992 0,4575692 ! tube development GO:0035295 83 81 0,000 0,45458992 0,45731944 ! lymphocyte activation GO:0046649 82 81 0,000 0,45458992 0,45706995 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,46274218 0,465013 ! ncRNA processing GO:0034470 83 83 0,000 0,46274218 0,46475958 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,46677339 0,46855303 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,47077494 0,47231259 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,47474705 0,47603853 GO:0006644|phospholipid metabolic process, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,48260378 0,48365349 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,49797315 0,49878506 ! regulation of response to stress GO:0080134 97 94 0,000 0,50548908 0,50603822 ! pattern specification process GO:0007389 96 94 0,000 0,50548908 0,5057635 ! response to other organism GO:0051707 101 100 0,000 0,5273811 0,5273811