pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6849-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 10,000 4,095E-12 9,853E-09 ! interphase GO:0051325 213 98 10,000 5,795E-12 6,972E-09 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 6,000 5,067E-11 4,064E-08 ! S phase GO:0051320 9 9 4,000 5,241E-10 3,152E-07 GO:0000084|S phase of mitotic cell cycle, ! induction of apoptosis by extracellular signals GO:0008624 89 49 6,000 8,126E-09 3,91E-06 ! mitotic sister chromatid segregation GO:0000070 57 36 5,000 3,762E-08 1,508E-05 ! sister chromatid segregation GO:0000819 58 37 5,000 4,47E-08 1,536E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 7,586E-08 2,282E-05 ! chromosome segregation GO:0007059 113 67 6,000 7,586E-08 2,028E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 8,419E-08 2,026E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,256E-07 2,748E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 1,511E-07 3,03E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 3,000 1,652E-07 3,057E-05 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 1,656E-07 2,846E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 1,73E-07 2,775E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 2,541E-07 3,821E-05 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of B cell proliferation GO:0030888 20 12 3,000 3,861E-07 5,464E-05 ! negative regulation of mast cell proliferation GO:0070667 23 12 3,000 3,861E-07 5,161E-05 GO:0042130|negative regulation of T cell proliferation, ! regulation of DNA metabolic process GO:0051052 178 97 6,000 9,791E-07 1,24E-04 ! negative regulation of leukocyte proliferation GO:0070664 31 16 3,000 1,396E-06 1,679E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! L-serine biosynthetic process GO:0006564 6 5 2,000 1,516E-06 1,737E-04 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 3,000 1,818E-06 1,988E-04 ! negative regulation of B cell activation GO:0050869 13 6 2,000 3,019E-06 3,159E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,654E-06 3,663E-04 ! negative regulation of T cell activation GO:0050868 40 20 3,000 3,654E-06 3,517E-04 ! cell structure disassembly during apoptosis GO:0006921 30 21 3,000 4,495E-06 4,16E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 5,263E-06 4,69E-04 ! apoptotic nuclear changes GO:0030262 32 22 3,000 5,471E-06 4,701E-04 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 6,012E-06 4,988E-04 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 3,000 7,881E-06 6,321E-04 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 8,141E-06 6,319E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 8,388E-06 6,307E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 8,388E-06 6,115E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,253E-05 8,868E-04 ! negative regulation of lymphocyte activation GO:0051250 53 27 3,000 1,285E-05 8,836E-04 ! regulation of DNA replication GO:0006275 101 56 4,000 1,295E-05 8,658E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,414E-05 9,194E-04 ! cell cycle arrest GO:0007050 213 100 5,000 1,734E-05 1,098E-03 ! L-serine metabolic process GO:0006563 18 10 2,000 1,783E-05 1,1E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,783E-05 1,073E-03 ! regulation of DNA replication initiation GO:0030174 14 10 2,000 1,783E-05 1,046E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 2,000 1,783E-05 1,022E-03 ! cell junction assembly GO:0034329 78 30 3,000 1,982E-05 1,109E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 3,000 1,982E-05 1,084E-03 ! regulation of B cell activation GO:0050864 50 30 3,000 1,982E-05 1,06E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,442E-05 1,277E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,442E-05 1,25E-03 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 19 12 2,000 3,243E-05 1,626E-03 GO:0050927|positive regulation of positive chemotaxis, ! cell cycle checkpoint GO:0000075 137 69 4,000 3,603E-05 1,769E-03 ! cell junction organization GO:0034330 86 36 3,000 4,155E-05 1,999E-03 ! negative regulation of cell activation GO:0050866 65 36 3,000 4,155E-05 1,96E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 4,2E-05 1,943E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 4,000 4,428E-05 2,01E-03 ! nucleus organization GO:0006997 67 38 3,000 5,163E-05 2,3E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 5,324E-05 2,329E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 5,324E-05 2,287E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 6,629E-05 2,798E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 6,92E-05 2,87E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 6,995E-05 2,852E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 7,799E-05 3,127E-03 GO:0045937|positive regulation of phosphate metabolic process, ! induction of apoptosis via death domain receptors GO:0008625 20 16 2,000 8,126E-05 3,205E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 9,829E-05 3,814E-03 ! glycolysis GO:0006096 65 45 3,000 1,012E-04 3,865E-03 ! positive regulation of protein modification process GO:0031401 136 88 4,000 1,157E-04 4,349E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,175E-04 4,348E-03 ! regulation of BMP signaling pathway GO:0030510 32 18 2,000 1,175E-04 4,283E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 2,000 1,175E-04 4,219E-03 ! cellular component disassembly GO:0022411 86 48 3,000 1,305E-04 4,618E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 1,39E-04 4,845E-03 ! G1 phase GO:0051318 40 19 2,000 1,39E-04 4,776E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 1,532E-04 5,191E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,628E-04 5,441E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,892E-04 6,236E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 1,892E-04 6,152E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,892E-04 6,07E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 2,182E-04 6,909E-03 ! glucose catabolic process GO:0006007 82 55 3,000 2,222E-04 6,942E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,5E-04 7,711E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 2,845E-04 8,665E-03 ! Notch receptor processing GO:0007220 8 5 1,000 2,845E-04 8,557E-03 ! glial cell fate commitment GO:0021781 13 5 1,000 2,845E-04 8,451E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 2,845E-04 8,348E-03 ! skeletal myofibril assembly GO:0014866 10 5 1,000 2,845E-04 8,248E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,845E-04 8,149E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,845E-04 8,054E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,845E-04 7,96E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 2,845E-04 7,868E-03 ! cardiac myofibril assembly GO:0055003 10 5 1,000 2,845E-04 7,779E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 2,845E-04 7,692E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,845E-04 7,606E-03 ! decidualization GO:0046697 11 5 1,000 2,845E-04 7,523E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,845E-04 7,441E-03 ! stem cell division GO:0017145 11 5 1,000 2,845E-04 7,361E-03 GO:0048103|somatic stem cell division, ! regulation of behavior GO:0050795 43 24 2,000 2,846E-04 7,284E-03 ! pallium development GO:0021543 49 24 2,000 2,846E-04 7,207E-03 ! DNA catabolic process GO:0006308 86 59 3,000 2,916E-04 7,308E-03 ! myelination GO:0042552 45 25 2,000 3,221E-04 7,989E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 3,627E-04 8,904E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 3,627E-04 8,814E-03 ! blastocyst development GO:0001824 49 26 2,000 3,627E-04 8,726E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 4,064E-04 9,681E-03 ! erythrocyte maturation GO:0043249 7 6 1,000 4,253E-04 0,01003133 ! neuron apoptosis GO:0051402 9 6 1,000 4,253E-04 9,934E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 4,253E-04 9,838E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 4,253E-04 9,745E-03 GO:0045686|negative regulation of glial cell differentiation, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 4,253E-04 9,653E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,253E-04 9,563E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 4,253E-04 9,474E-03 ! maternal placenta development GO:0001893 12 6 1,000 4,253E-04 9,387E-03 ! actin filament organization GO:0007015 148 66 3,000 4,485E-04 9,809E-03 ! developmental maturation GO:0021700 116 66 3,000 4,485E-04 9,721E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 4,534E-04 9,739E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 4,534E-04 9,653E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 4,75E-04 0,01002406 ! homeostasis of number of cells GO:0048872 114 67 3,000 4,75E-04 9,937E-03 ! hexose catabolic process GO:0019320 104 67 3,000 4,75E-04 9,851E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 4,75E-04 9,767E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 5,313E-04 0,01083211 ! ensheathment of neurons GO:0007272 57 30 2,000 5,575E-04 0,01127102 GO:0008366|axon ensheathment, ! regulation of lipid kinase activity GO:0043550 13 7 1,000 5,933E-04 0,01189507 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,933E-04 0,01179677 ! lipoprotein transport GO:0042953 14 7 1,000 5,933E-04 0,01170007 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 5,933E-04 0,01160495 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 5,933E-04 0,01151136 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 5,933E-04 0,01141927 ! peptidyl-histidine modification GO:0018202 16 7 1,000 5,933E-04 0,01132864 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 5,933E-04 0,01123944 ! erythrocyte differentiation GO:0030218 55 31 2,000 6,148E-04 0,01155559 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 6,148E-04 0,01146601 ! spindle organization GO:0007051 46 32 2,000 6,757E-04 0,01250544 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 6,757E-04 0,01240998 ! leukocyte chemotaxis GO:0030595 50 33 2,000 7,403E-04 0,01349429 GO:0060326|cell chemotaxis, ! monosaccharide catabolic process GO:0046365 115 76 3,000 7,658E-04 0,01385297 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 7,882E-04 0,01415287 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 7,882E-04 0,01404803 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,882E-04 0,01394474 ! hemoglobin metabolic process GO:0020027 13 8 1,000 7,882E-04 0,01384295 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,882E-04 0,01374264 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 7,882E-04 0,01364377 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 7,882E-04 0,01354632 ! cardiac muscle cell development GO:0055013 13 8 1,000 7,882E-04 0,01345025 ! blastocyst growth GO:0001832 19 8 1,000 7,882E-04 0,01335553 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 7,882E-04 0,01326213 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 7,882E-04 0,01317003 GO:0000076|DNA replication checkpoint, ! telencephalon development GO:0021537 68 35 2,000 8,811E-04 0,01462078 ! DNA integrity checkpoint GO:0031570 75 36 2,000 9,575E-04 0,01577845 ! DNA synthesis during DNA repair GO:0000731 14 9 1,000 1,01E-03 0,01652873 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,01E-03 0,01641704 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 1,01E-03 0,01630686 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,01E-03 0,01619815 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,01E-03 0,01609088 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 1,01E-03 0,01598502 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,01E-03 0,01588054 ! motor axon guidance GO:0008045 16 9 1,000 1,01E-03 0,01577742 ! erythrocyte development GO:0048821 15 9 1,000 1,01E-03 0,01567563 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 1,01E-03 0,01557514 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,01E-03 0,01547594 ! branched chain family amino acid catabolic process GO:0009083 17 9 1,000 1,01E-03 0,01537799 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,01E-03 0,01528127 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 2,000 1,038E-03 0,01560669 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,038E-03 0,01550975 ! negative regulation of transport GO:0051051 153 84 3,000 1,114E-03 0,01654487 ! negative regulation of growth GO:0045926 155 84 3,000 1,114E-03 0,01644337 ! erythrocyte homeostasis GO:0034101 64 38 2,000 1,122E-03 0,0164662 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,211E-03 0,01766066 ! mitochondrion organization GO:0007005 148 86 3,000 1,216E-03 0,01762304 ! alcohol catabolic process GO:0046164 130 86 3,000 1,216E-03 0,01751752 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,258E-03 0,01801445 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,258E-03 0,01790785 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,258E-03 0,01780251 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,258E-03 0,01769841 ! pathogenesis GO:0009405 13 10 1,000 1,258E-03 0,01759551 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,258E-03 0,0174938 GO:0045685|regulation of glial cell differentiation, ! blastocyst formation GO:0001825 17 10 1,000 1,258E-03 0,01739326 ! keratinocyte differentiation GO:0030216 62 41 2,000 1,402E-03 0,01927062 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,402E-03 0,01916112 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 1,532E-03 0,02082435 GO:0046579|positive regulation of Ras protein signal transduction, ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,532E-03 0,02070736 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,532E-03 0,02059167 GO:0010812|negative regulation of cell-substrate adhesion, ! neuroblast proliferation GO:0007405 24 11 1,000 1,532E-03 0,02047727 ! nucleus localization GO:0051647 19 11 1,000 1,532E-03 0,02036414 ! striated muscle cell differentiation GO:0051146 82 43 2,000 1,61E-03 0,02128342 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 1,61E-03 0,02116712 ! regulation of T cell activation GO:0050863 158 94 3,000 1,689E-03 0,02208601 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 1,721E-03 0,02238224 ! forebrain development GO:0030900 188 95 3,000 1,756E-03 0,0227145 ! hippocampus development GO:0021766 26 12 1,000 1,832E-03 0,02356943 ! focal adhesion formation GO:0048041 35 12 1,000 1,832E-03 0,02344406 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,832E-03 0,02332002 GO:0006509|membrane protein ectodomain proteolysis, ! T cell homeostasis GO:0043029 25 12 1,000 1,832E-03 0,02319728 ! leukocyte migration GO:0050900 68 45 2,000 1,837E-03 0,02313658 ! epidermal cell differentiation GO:0009913 68 46 2,000 1,957E-03 0,02452535 ! pigmentation GO:0043473 100 46 2,000 1,957E-03 0,02439827 ! response to insulin stimulus GO:0032868 95 46 2,000 1,957E-03 0,02427251 ! positive regulation of defense response GO:0031349 76 47 2,000 2,082E-03 0,02569342 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 2,157E-03 0,026482 ! Golgi organization GO:0007030 24 13 1,000 2,157E-03 0,02634758 ! cell-cell junction assembly GO:0007043 27 13 1,000 2,157E-03 0,02621451 ! chromatin silencing GO:0006342 26 13 1,000 2,157E-03 0,02608278 ! embryonic placenta development GO:0001892 23 13 1,000 2,157E-03 0,02595236 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,157E-03 0,02582325 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,213E-03 0,02635295 ! activation of caspase activity GO:0006919 84 48 2,000 2,213E-03 0,02622313 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,213E-03 0,02609459 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,213E-03 0,0259673 ! regulation of action potential GO:0001508 95 49 2,000 2,348E-03 0,02741874 ! embryo implantation GO:0007566 30 14 1,000 2,508E-03 0,02915074 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 2,508E-03 0,02901059 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 2,633E-03 0,03030835 ! regulation of muscle contraction GO:0006937 81 52 2,000 2,783E-03 0,03188553 ! cartilage development GO:0051216 90 52 2,000 2,783E-03 0,03173442 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 2,884E-03 0,03272644 ! heterophilic cell adhesion GO:0007157 39 15 1,000 2,884E-03 0,03257279 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,884E-03 0,03242058 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! glycoprotein catabolic process GO:0006516 26 15 1,000 2,884E-03 0,03226979 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,884E-03 0,03212039 ! cell maturation GO:0048469 100 53 2,000 2,938E-03 0,03258042 ! response to UV GO:0009411 104 53 2,000 2,938E-03 0,03243096 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,265E-03 0,03587166 GO:0010952|positive regulation of peptidase activity, ! negative regulation of cell motion GO:0051271 134 55 2,000 3,265E-03 0,03570861 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,284E-03 0,03575211 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,284E-03 0,03559107 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 3,284E-03 0,03543147 ! DNA replication initiation GO:0006270 27 16 1,000 3,284E-03 0,03527329 ! lipid modification GO:0030258 97 57 2,000 3,613E-03 0,03863709 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,709E-03 0,03948311 ! limbic system development GO:0021761 36 17 1,000 3,709E-03 0,03930918 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 3,709E-03 0,03913677 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,709E-03 0,03896586 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 3,709E-03 0,03879645 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 3,983E-03 0,04148625 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,158E-03 0,04311745 ! memory GO:0007613 31 18 1,000 4,158E-03 0,0429324 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,158E-03 0,04274893 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,158E-03 0,04256702 ! regulation of heart contraction GO:0008016 110 60 2,000 4,176E-03 0,04257759 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 4,176E-03 0,04239794 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,176E-03 0,0422198 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 4,375E-03 0,04404514 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 4,63E-03 0,04641987 ! lipid phosphorylation GO:0046834 35 19 1,000 4,63E-03 0,04622726 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,63E-03 0,04603624 ! cerebral cortex development GO:0021987 36 19 1,000 4,63E-03 0,04584679 ! pigmentation during development GO:0048066 41 19 1,000 4,63E-03 0,04565889 ! neuromuscular junction development GO:0007528 34 19 1,000 4,63E-03 0,04547253 ! plasma membrane fusion GO:0045026 28 19 1,000 4,63E-03 0,04528768 ! heart process GO:0003015 30 19 1,000 4,63E-03 0,04510433 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 1,000 4,63E-03 0,04492246 GO:0006692|prostanoid metabolic process, ! cell-cell junction organization GO:0045216 35 19 1,000 4,63E-03 0,04474205 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,63E-03 0,04456308 ! response to alkaloid GO:0043279 38 20 1,000 5,127E-03 0,04914384 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 5,127E-03 0,04894882 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,127E-03 0,04875535 ! actin filament-based movement GO:0030048 43 20 1,000 5,127E-03 0,0485634 ! negative regulation of translation GO:0017148 29 20 1,000 5,127E-03 0,04837295 ! myeloid cell differentiation GO:0030099 111 65 2,000 5,228E-03 0,04913209 ! hindlimb morphogenesis GO:0035137 43 21 1,000 5,647E-03 0,05286231 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 5,647E-03 0,05265741 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 5,647E-03 0,0524541 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 6,189E-03 0,05727564 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 6,189E-03 0,0570562 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 6,189E-03 0,05683842 GO:0060415|muscle tissue morphogenesis, ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,189E-03 0,05662231 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,189E-03 0,05640783 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,755E-03 0,06133072 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 6,755E-03 0,06110015 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,755E-03 0,06087131 ! leukocyte adhesion GO:0007159 50 23 1,000 6,755E-03 0,06064418 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,755E-03 0,06041874 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 6,755E-03 0,06019497 ! synaptic vesicle transport GO:0048489 46 23 1,000 6,755E-03 0,05997284 ! platelet activation GO:0030168 37 23 1,000 6,755E-03 0,05975235 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 6,755E-03 0,05953348 GO:0006099|tricarboxylic acid cycle, ! regulation of caspase activity GO:0043281 122 72 2,000 6,945E-03 0,06098757 ! learning or memory GO:0007611 147 73 2,000 7,215E-03 0,06312339 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 7,343E-03 0,06401417 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 7,343E-03 0,06378307 ! regulation of transmembrane transport GO:0034762 38 24 1,000 7,343E-03 0,06355364 ! leukocyte homeostasis GO:0001776 44 24 1,000 7,343E-03 0,06332585 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 7,49E-03 0,06436431 ! organelle localization GO:0051640 136 74 2,000 7,49E-03 0,06413526 ! vasculogenesis GO:0001570 46 25 1,000 7,954E-03 0,06786122 ! negative regulation of DNA replication GO:0008156 42 25 1,000 7,954E-03 0,06762143 ! coenzyme catabolic process GO:0009109 39 25 1,000 7,954E-03 0,06738332 ! negative regulation of cell development GO:0010721 73 25 1,000 7,954E-03 0,06714689 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 7,954E-03 0,06691211 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 8,586E-03 0,07198218 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 8,586E-03 0,07173225 ! microtubule organizing center organization GO:0031023 39 26 1,000 8,586E-03 0,07148404 GO:0051297|centrosome organization, ! positive regulation of nuclear division GO:0051785 40 26 1,000 8,586E-03 0,07123754 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 8,586E-03 0,07099274 ! regulation of peptidase activity GO:0052547 134 79 2,000 8,961E-03 0,07383904 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 8,961E-03 0,07358703 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 9,241E-03 0,07562372 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 9,241E-03 0,07536737 ! protein amino acid acylation GO:0043543 55 27 1,000 9,241E-03 0,07511275 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 9,241E-03 0,07485985 ! muscle cell differentiation GO:0042692 159 80 2,000 9,274E-03 0,07487922 ! protein import into nucleus GO:0006606 158 80 2,000 9,274E-03 0,07462879 ! response to hypoxia GO:0001666 171 81 2,000 9,594E-03 0,07694079 ! nuclear import GO:0051170 161 81 2,000 9,594E-03 0,07668517 ! lipid oxidation GO:0034440 43 28 1,000 9,917E-03 0,07900571 GO:0019395|fatty acid oxidation, ! cellular response to hormone stimulus GO:0032870 167 82 2,000 9,919E-03 0,07876483 ! response to oxygen levels GO:0070482 176 83 2,000 0,01025128 0,08113351 ! regulation of ligase activity GO:0051340 142 84 2,000 0,0105897 0,08353711 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01061402 0,08345536 ! respiratory gaseous exchange GO:0007585 57 29 1,000 0,01061402 0,08318352 ! cell fate determination GO:0001709 60 29 1,000 0,01061402 0,08291345 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01061402 0,08264512 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01128581 0,08759248 ! myofibril assembly GO:0030239 47 30 1,000 0,01133235 0,08767085 GO:0055002|striated muscle cell development, ! cofactor catabolic process GO:0051187 51 30 1,000 0,01133235 0,08738985 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01164355 0,08950282 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01207149 0,09249686 ! fatty acid catabolic process GO:0009062 48 31 1,000 0,01207149 0,09220322 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01207149 0,09191144 GO:0043433|negative regulation of transcription factor activity, ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01237848 0,09395147 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,0127557 0,09651012 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01283121 0,09677712 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01283121 0,09647469 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01283121 0,09617415 ! muscle cell development GO:0055001 49 32 1,000 0,01283121 0,09587547 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01283121 0,09557864 ! hindbrain development GO:0030902 61 32 1,000 0,01283121 0,09528365 ! gene silencing GO:0016458 65 32 1,000 0,01283121 0,09499047 ! regulation of defense response GO:0031347 149 92 2,000 0,01352976 0,09985461 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01361127 0,10014898 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01361127 0,09984365 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01361127 0,09954018 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01392662 0,10153774 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01392662 0,10123098 ! female pregnancy GO:0007565 164 94 2,000 0,01433006 0,10384977 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01441143 0,1041258 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01441143 0,10381405 ! glial cell differentiation GO:0010001 63 34 1,000 0,01441143 0,10350415 ! placenta development GO:0001890 53 34 1,000 0,01441143 0,1031961 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01441143 0,10288988 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 0,01474008 0,10492497 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01523144 0,10810281 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01523144 0,10778486 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01523144 0,10746878 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01523144 0,10715454 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01523144 0,10684214 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01523144 0,10653155 ! carboxylic acid catabolic process GO:0046395 156 98 2,000 0,0160098 0,11165094 GO:0016054|organic acid catabolic process, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01607109 0,11175446 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01607109 0,1114324 ! aerobic respiration GO:0009060 55 36 1,000 0,01607109 0,11111219 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01607109 0,11079382 ! meiosis I GO:0007127 65 37 1,000 0,01693013 0,11638256 ! actomyosin structure organization GO:0031032 62 37 1,000 0,01693013 0,11605099 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01693013 0,1157213 ! regulation of protein stability GO:0031647 73 37 1,000 0,01693013 0,11539348 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01780834 0,12103635 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01780834 0,1206954 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01780834 0,12035637 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,01870549 0,12606554 ! learning GO:0007612 77 39 1,000 0,01870549 0,12571341 ! ear morphogenesis GO:0042471 60 39 1,000 0,01870549 0,12536323 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01962134 0,13113597 ! negative regulation of binding GO:0051100 72 40 1,000 0,01962134 0,13077272 ! maintenance of protein location GO:0045185 91 40 1,000 0,01962134 0,13041147 ! cytokinesis GO:0000910 72 40 1,000 0,01962134 0,13005221 ! gliogenesis GO:0042063 88 41 1,000 0,02055569 0,13587083 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02150829 0,14177796 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02150829 0,14139059 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02150829 0,14100532 ! glucose transport GO:0015758 65 43 1,000 0,02247894 0,14696831 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,02247894 0,14657002 ! hexose transport GO:0008645 67 44 1,000 0,02346742 0,15260164 GO:0015749|monosaccharide transport, ! developmental growth GO:0048589 82 44 1,000 0,02346742 0,15219031 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02346742 0,1517812 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,0244735 0,1578639 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,0244735 0,1574418 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,0244735 0,15702196 ! cell growth GO:0016049 84 45 1,000 0,0244735 0,15660435 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02549697 0,16272071 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02549697 0,16229023 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02549697 0,16186202 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02660907 0,16847743 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02660907 0,16803523 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02660907 0,16759535 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02660907 0,16715776 ! neuron fate determination GO:0048664 7 5 0,000 0,02660907 0,16672246 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02660907 0,16628941 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02660907 0,16585861 ! polyol transport GO:0015791 12 5 0,000 0,02660907 0,16543004 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02660907 0,16500367 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02660907 0,1645795 ! response to superoxide GO:0000303 10 5 0,000 0,02660907 0,1641575 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02660907 0,16373766 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02660907 0,16331996 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02660907 0,16290439 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02660907 0,16249092 ! female meiosis GO:0007143 7 5 0,000 0,02660907 0,16207955 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02660907 0,16167026 ! cobalt ion transport GO:0006824 11 5 0,000 0,02660907 0,16126303 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02660907 0,16085785 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02660907 0,1604547 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02660907 0,16005356 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02660907 0,15965442 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02660907 0,15925727 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02660907 0,15886209 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02660907 0,15846887 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02660907 0,15807759 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02660907 0,15768824 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02660907 0,1573008 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02660907 0,15691525 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02660907 0,1565316 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02660907 0,15614981 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02660907 0,15576989 ! negative chemotaxis GO:0050919 14 5 0,000 0,02660907 0,15539181 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02660907 0,15501555 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02660907 0,15464112 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02660907 0,15426849 ! behavioral response to pain GO:0048266 9 5 0,000 0,02660907 0,15389765 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02660907 0,15352859 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02660907 0,1531613 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02660907 0,15279576 ! micturition GO:0060073 9 5 0,000 0,02660907 0,15243196 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02660907 0,15206989 ! copulation GO:0007620 9 5 0,000 0,02660907 0,15170954 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02660907 0,15135088 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02660907 0,15099392 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02660907 0,15063864 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02660907 0,15028503 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02660907 0,14993308 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02660907 0,14958277 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02660907 0,14923409 ! grooming behavior GO:0007625 6 5 0,000 0,02660907 0,14888703 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02660907 0,14854159 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02660907 0,14819774 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02660907 0,14785548 ! response to protozoan GO:0001562 10 5 0,000 0,02660907 0,1475148 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02660907 0,14717569 ! lymph vessel development GO:0001945 10 5 0,000 0,02660907 0,14683813 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02660907 0,14650211 ! endochondral ossification GO:0001958 16 5 0,000 0,02660907 0,14616763 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02660907 0,14583468 ! parathyroid gland development GO:0060017 13 5 0,000 0,02660907 0,14550324 ! anagen GO:0042640 6 5 0,000 0,02660907 0,1451733 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02660907 0,14484485 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02660907 0,14451789 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02660907 0,1441924 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02660907 0,14386837 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02660907 0,14354579 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02660907 0,14322466 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02660907 0,14290496 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02660907 0,14258669 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02660907 0,14226983 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02660907 0,14195438 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02660907 0,14164032 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02660907 0,14132765 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02660907 0,14101635 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02660907 0,14070643 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02660907 0,14039786 ! histidine catabolic process GO:0006548 6 5 0,000 0,02660907 0,14009064 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02660907 0,13978477 ! microvillus organization GO:0032528 7 5 0,000 0,02660907 0,13948023 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02660907 0,13917701 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02660907 0,13887511 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02660907 0,13857451 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02660907 0,13827521 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02660907 0,13797721 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02660907 0,13768048 ! polyol catabolic process GO:0046174 7 5 0,000 0,02660907 0,13738503 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02660907 0,13709084 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02660907 0,13679791 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02660907 0,13650623 ! muscle cell migration GO:0014812 8 5 0,000 0,02660907 0,1362158 ! mitochondrial fission GO:0000266 8 5 0,000 0,02660907 0,13592659 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02660907 0,13563861 ! mRNA transcription GO:0009299 9 5 0,000 0,02660907 0,13535185 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02660907 0,1350663 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02660907 0,13478194 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02660907 0,13449879 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02660907 0,13421682 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02660907 0,13393603 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02660907 0,13365642 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02660907 0,13337797 ! response to food GO:0032094 6 5 0,000 0,02660907 0,13310067 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02660907 0,13282453 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02660907 0,13254953 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02660907 0,13227567 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02660907 0,13200294 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02660907 0,13173132 ! forebrain neuron development GO:0021884 13 5 0,000 0,02660907 0,13146083 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02660907 0,13119144 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02660907 0,13092316 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02660907 0,13065597 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02660907 0,13038987 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02660907 0,13012485 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02660907 0,1298609 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02660907 0,12959802 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02660907 0,12933621 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02660907 0,12907545 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02660907 0,12881574 ! basic amino acid transport GO:0015802 11 5 0,000 0,02660907 0,12855708 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02660907 0,12829945 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02660907 0,12804285 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02660907 0,12778727 ! depyrimidination GO:0045008 10 5 0,000 0,02660907 0,12753272 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02660907 0,12727917 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02660907 0,12702663 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02660907 0,1267751 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02660907 0,12652455 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02660907 0,126275 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02660907 0,12602642 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02660907 0,12577883 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02660907 0,1255322 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02660907 0,12528654 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02660907 0,12504184 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02660907 0,1247981 ! response to arsenic GO:0046685 10 5 0,000 0,02660907 0,1245553 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02660907 0,12431344 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02660907 0,12407253 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02660907 0,12383254 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02660907 0,12359348 ! response to cadmium ion GO:0046686 7 5 0,000 0,02660907 0,12335534 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02660907 0,12311812 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02660907 0,12288181 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02660907 0,12264641 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02660907 0,1224119 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02660907 0,12217829 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02660907 0,12194557 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02660907 0,12171373 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02660907 0,12148278 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02660907 0,1212527 ! neural tube patterning GO:0021532 7 5 0,000 0,02660907 0,12102349 ! embryonic cleavage GO:0040016 6 5 0,000 0,02660907 0,12079514 ! peroxisome fission GO:0016559 5 5 0,000 0,02660907 0,12056765 ! histone demethylation GO:0016577 10 5 0,000 0,02660907 0,12034102 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02660907 0,12011524 ! mitotic recombination GO:0006312 9 5 0,000 0,02660907 0,11989031 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02660907 0,11966621 ! metaphase plate congression GO:0051310 7 5 0,000 0,02660907 0,11944295 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02660907 0,11922053 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02660907 0,11899893 ! enteric nervous system development GO:0048484 8 5 0,000 0,02660907 0,11877815 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02660907 0,11855819 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02660907 0,11833905 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02660907 0,11812071 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02660907 0,11790317 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02660907 0,11768644 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02660907 0,1174705 ! plasminogen activation GO:0031639 5 5 0,000 0,02660907 0,11725536 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02660907 0,11704099 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02660907 0,11682742 ! metaphase GO:0051323 8 5 0,000 0,02660907 0,11661462 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02660907 0,11640259 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02660907 0,11619133 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02660907 0,11598084 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02660907 0,11577111 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02660907 0,11556214 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02660907 0,11535392 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02660907 0,11514645 ! response to redox state GO:0051775 5 5 0,000 0,02660907 0,11493972 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02660907 0,11473373 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02660907 0,11452849 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02660907 0,11432397 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02660907 0,11412019 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02660907 0,11391712 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02660907 0,11371478 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02660907 0,11351316 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02660907 0,11331225 ! striatum development GO:0021756 9 5 0,000 0,02660907 0,11311206 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02660907 0,11291256 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02660907 0,11271377 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02660907 0,11251568 ! glial cell migration GO:0008347 11 5 0,000 0,02660907 0,11231829 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02660907 0,11212158 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02660907 0,11192557 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02660907 0,11173023 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02660907 0,11153558 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02660907 0,11134161 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02660907 0,11114831 ! neuroprotection GO:0043526 6 5 0,000 0,02660907 0,11095567 ! neural plate development GO:0001840 8 5 0,000 0,02660907 0,11076371 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02660907 0,11057241 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02660907 0,11038177 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02660907 0,11019178 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02660907 0,11000245 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02660907 0,10981376 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02660907 0,10962573 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02660907 0,10943833 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02660907 0,10925158 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02660907 0,10906546 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02660907 0,10887997 ! spindle assembly GO:0051225 6 5 0,000 0,02660907 0,10869512 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02660907 0,10851089 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02660907 0,10832728 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02660907 0,1081443 ! drug metabolic process GO:0017144 6 5 0,000 0,02660907 0,10796193 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02660907 0,10778017 ! organ regeneration GO:0031100 7 5 0,000 0,02660907 0,10759903 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02660907 0,1074185 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02660907 0,10723857 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02660907 0,10705924 ! Notch signaling pathway GO:0007219 96 48 1,000 0,02759523 0,11084161 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,0286696 0,11496509 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,0286696 0,1147738 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,0286696 0,11458315 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0286696 0,11439312 ! regulation of ossification GO:0030278 117 50 1,000 0,02976051 0,11854933 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02976051 0,11835338 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03086777 0,12255421 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,03086777 0,12235231 ! vesicle organization GO:0016050 107 51 1,000 0,03086777 0,12215107 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03184583 0,12581456 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03184583 0,12560831 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03184583 0,12540273 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03184583 0,12519783 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03184583 0,12499359 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03184583 0,12479002 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03184583 0,1245871 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03184583 0,12438485 ! sleep GO:0030431 13 6 0,000 0,03184583 0,12418326 ! response to oxygen radical GO:0000305 11 6 0,000 0,03184583 0,12398231 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03184583 0,12378202 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03184583 0,12358237 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03184583 0,12338336 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03184583 0,123185 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03184583 0,12298727 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03184583 0,12279018 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03184583 0,12259371 ! forebrain regionalization GO:0021871 8 6 0,000 0,03184583 0,12239787 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03184583 0,12220266 ! male meiosis GO:0007140 7 6 0,000 0,03184583 0,12200807 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03184583 0,1218141 ! response to zinc ion GO:0010043 9 6 0,000 0,03184583 0,12162075 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03184583 0,121428 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03184583 0,12123587 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03184583 0,12104434 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03184583 0,12085342 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03184583 0,1206631 ! malate metabolic process GO:0006108 11 6 0,000 0,03184583 0,12047338 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03184583 0,12028425 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03184583 0,12009572 ! protein refolding GO:0042026 15 6 0,000 0,03184583 0,11990778 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03184583 0,11972042 ! opsonization GO:0008228 8 6 0,000 0,03184583 0,11953365 ! mating behavior GO:0007617 7 6 0,000 0,03184583 0,11934746 ! neuron remodeling GO:0016322 15 6 0,000 0,03184583 0,11916185 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03184583 0,11897682 ! equilibrioception GO:0050957 14 6 0,000 0,03184583 0,11879236 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03184583 0,11860847 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03184583 0,11842515 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03184583 0,11824239 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03184583 0,1180602 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03184583 0,11787857 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03184583 0,1176975 ! toxin metabolic process GO:0009404 11 6 0,000 0,03184583 0,11751698 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03184583 0,11733701 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03184583 0,1171576 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03184583 0,11697873 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03184583 0,11680041 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03184583 0,11662263 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03184583 0,11644539 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03184583 0,11626869 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03184583 0,11609253 ! thymic T cell selection GO:0045061 12 6 0,000 0,03184583 0,1159169 ! protein lipoylation GO:0009249 10 6 0,000 0,03184583 0,1157418 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03184583 0,11556722 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03184583 0,11539318 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03184583 0,11521965 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03184583 0,11504665 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03184583 0,11487417 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03184583 0,1147022 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03184583 0,11453075 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03184583 0,11435981 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03184583 0,11418937 ! hyperosmotic response GO:0006972 9 6 0,000 0,03184583 0,11401945 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03184583 0,11385003 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03184583 0,11368111 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03184583 0,1135127 ! urea metabolic process GO:0019627 7 6 0,000 0,03184583 0,11334478 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03184583 0,11317736 ! neutrophil activation GO:0042119 8 6 0,000 0,03184583 0,11301043 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03184583 0,11284399 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03184583 0,11267804 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03184583 0,11251258 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03184583 0,11234761 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03184583 0,11218312 ! nucleoside salvage GO:0043174 9 6 0,000 0,03184583 0,11201911 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03184583 0,11185558 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03184583 0,11169252 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03184583 0,11152994 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03184583 0,11136783 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03184583 0,1112062 ! carnitine transport GO:0015879 10 6 0,000 0,03184583 0,11104503 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03184583 0,11088433 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03184583 0,11072409 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03184583 0,11056431 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03184583 0,110405 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03184583 0,11024614 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03184583 0,11008774 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03184583 0,1099298 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03184583 0,10977231 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03184583 0,10961526 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03184583 0,10945867 ! monocyte differentiation GO:0030224 12 6 0,000 0,03184583 0,10930252 ! neural nucleus development GO:0048857 14 6 0,000 0,03184583 0,10914682 ! response to UV-C GO:0010225 11 6 0,000 0,03184583 0,10899156 ! astrocyte development GO:0014002 15 6 0,000 0,03184583 0,10883675 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03184583 0,10868237 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03184583 0,10852843 ! interaction with symbiont GO:0051702 13 6 0,000 0,03184583 0,10837492 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03184583 0,10822185 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03184583 0,10806921 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03184583 0,107917 ! response to copper ion GO:0046688 10 6 0,000 0,03184583 0,10776522 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03184583 0,10761386 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03184583 0,10746293 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03184583 0,10731242 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03184583 0,10716233 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03184583 0,10701267 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03184583 0,10686342 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03184583 0,10671458 ! hair follicle maturation GO:0048820 7 6 0,000 0,03184583 0,10656616 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03184583 0,10641815 ! Schwann cell development GO:0014044 15 6 0,000 0,03184583 0,10627055 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03184583 0,10612336 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03184583 0,10597658 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03184583 0,10583021 ! subpallium development GO:0021544 10 6 0,000 0,03184583 0,10568423 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03184583 0,10553866 ! histone ubiquitination GO:0016574 8 6 0,000 0,03184583 0,10539349 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03184583 0,10524872 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03184583 0,10510435 ! G2 phase GO:0051319 16 6 0,000 0,03184583 0,10496037 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03184583 0,10481678 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03184583 0,10467359 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03184583 0,10453079 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03184583 0,10438838 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03184583 0,10424635 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03184583 0,10410471 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03184583 0,10396346 ! receptor internalization GO:0031623 10 6 0,000 0,03184583 0,10382259 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03184583 0,1036821 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03184583 0,10354199 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03184583 0,10340225 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03184583 0,1032629 ! protein deubiquitination GO:0016579 14 6 0,000 0,03184583 0,10312392 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03184583 0,10298531 ! protein destabilization GO:0031648 9 6 0,000 0,03184583 0,10284707 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03184583 0,10270921 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03184583 0,10257171 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03184583 0,10243458 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03184583 0,10229782 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03184583 0,10216143 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03184583 0,10202539 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03184583 0,10188972 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03184583 0,10175441 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03184583 0,10161946 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03184583 0,10148486 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03184583 0,10135062 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03184583 0,10121674 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03184583 0,10108321 ! catecholamine transport GO:0051937 9 6 0,000 0,03184583 0,10095003 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03184583 0,1008172 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03184583 0,10068472 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03184583 0,10055258 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03184583 0,1004208 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03184583 0,10028936 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03184583 0,10015826 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03184583 0,10002751 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03184583 0,09989709 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03184583 0,09976702 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03199116 0,10009197 ! membrane fusion GO:0006944 110 52 1,000 0,03199116 0,09996198 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03199116 0,09983233 ! synapse organization GO:0050808 85 52 1,000 0,03199116 0,09970301 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,03313048 0,10312022 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,03313048 0,10298699 ! aging GO:0007568 103 55 1,000 0,03545611 0,11007407 ! heart morphogenesis GO:0003007 97 55 1,000 0,03545611 0,10993222 ! regulation of actin filament length GO:0030832 105 56 1,000 0,03664202 0,11346295 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03664202 0,11331711 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03664202 0,11317165 ! tRNA transcription GO:0009304 14 7 0,000 0,03705459 0,11429916 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03705459 0,11415281 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03705459 0,11400684 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03705459 0,11386123 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03705459 0,113716 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03705459 0,11357114 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03705459 0,11342665 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03705459 0,11328252 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03705459 0,11313876 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03705459 0,11299537 ! prostate gland development GO:0030850 13 7 0,000 0,03705459 0,11285234 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03705459 0,11270967 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03705459 0,11256736 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03705459 0,11242541 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03705459 0,11228381 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03705459 0,11214257 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03705459 0,11200169 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03705459 0,11186116 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03705459 0,11172099 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03705459 0,11158116 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03705459 0,11144168 ! glycolipid transport GO:0046836 10 7 0,000 0,03705459 0,11130255 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03705459 0,11116377 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03705459 0,11102534 ! neuron adhesion GO:0007158 12 7 0,000 0,03705459 0,11088725 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03705459 0,1107495 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03705459 0,11061209 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03705459 0,11047503 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03705459 0,1103383 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03705459 0,11020191 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03705459 0,11006586 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03705459 0,10993014 ! mRNA stabilization GO:0048255 18 7 0,000 0,03705459 0,10979476 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03705459 0,10965971 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03705459 0,109525 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03705459 0,10939061 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03705459 0,10925655 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03705459 0,10912282 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03705459 0,10898942 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03705459 0,10885634 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03705459 0,10872359 ! rhythmic behavior GO:0007622 15 7 0,000 0,03705459 0,10859116 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03705459 0,10845906 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03705459 0,10832727 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03705459 0,10819581 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03705459 0,10806466 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03705459 0,10793383 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03705459 0,10780332 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03705459 0,10767312 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03705459 0,10754324 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03705459 0,10741367 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03705459 0,10728441 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03705459 0,10715546 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03705459 0,10702683 ! spinal cord patterning GO:0021511 13 7 0,000 0,03705459 0,1068985 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03705459 0,10677047 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03705459 0,10664276 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03705459 0,10651535 ! adrenal gland development GO:0030325 17 7 0,000 0,03705459 0,10638824 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03705459 0,10626144 ! ovulation GO:0030728 9 7 0,000 0,03705459 0,10613494 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03705459 0,10600874 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03705459 0,10588283 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03705459 0,10575723 ! microtubule nucleation GO:0007020 20 7 0,000 0,03705459 0,10563193 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03705459 0,10550692 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03705459 0,10538221 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03705459 0,10525779 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03705459 0,10513366 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03705459 0,10500983 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03705459 0,10488629 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03705459 0,10476304 ! galactose metabolic process GO:0006012 13 7 0,000 0,03705459 0,10464008 ! vesicle fusion GO:0006906 17 7 0,000 0,03705459 0,1045174 ! response to dietary excess GO:0002021 8 7 0,000 0,03705459 0,10439502 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03705459 0,10427292 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03705459 0,10415111 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03705459 0,10402958 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03705459 0,10390833 ! organ growth GO:0035265 15 7 0,000 0,03705459 0,10378736 ! purine salvage GO:0043101 10 7 0,000 0,03705459 0,10366668 ! nucleoside transport GO:0015858 8 7 0,000 0,03705459 0,10354628 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03705459 0,10342616 ! parturition GO:0007567 14 7 0,000 0,03705459 0,10330631 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03705459 0,10318674 ! rRNA modification GO:0000154 14 7 0,000 0,03705459 0,10306745 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03705459 0,10294844 ! spindle checkpoint GO:0031577 15 7 0,000 0,03705459 0,1028297 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03705459 0,10271123 ! macrophage differentiation GO:0030225 11 7 0,000 0,03705459 0,10259303 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03705459 0,10247511 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03705459 0,10235746 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03705459 0,10224008 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03705459 0,10212296 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03705459 0,10200612 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03705459 0,10188954 ! fibrinolysis GO:0042730 10 7 0,000 0,03705459 0,10177323 ! eating behavior GO:0042755 7 7 0,000 0,03705459 0,10165718 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03705459 0,1015414 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03705459 0,10142588 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03705459 0,10131062 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03705459 0,10119563 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03705459 0,10108089 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03705459 0,10096642 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03705459 0,1008522 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03705459 0,10073824 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03705459 0,10062454 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03705459 0,1005111 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03705459 0,10039791 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03705459 0,10028498 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03705459 0,1001723 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03705459 0,10005987 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03705459 0,0999477 ! regulation of meiosis GO:0040020 12 7 0,000 0,03705459 0,09983577 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03705459 0,0997241 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03705459 0,09961268 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03705459 0,0995015 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03705459 0,09939058 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03705459 0,0992799 ! transcription termination GO:0006353 13 7 0,000 0,03705459 0,09916946 ! response to tumor cell GO:0002347 13 7 0,000 0,03705459 0,09905927 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03705459 0,09894933 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03705459 0,09883963 ! anaphase GO:0051322 17 7 0,000 0,03705459 0,09873017 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 18 7 0,000 0,03705459 0,09862096 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03705459 0,09851198 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03705459 0,09840325 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03705459 0,09829476 ! diuresis GO:0030146 12 7 0,000 0,03705459 0,0981865 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03705459 0,09807849 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03705459 0,09797071 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03705459 0,09786317 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03705459 0,09775586 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03705459 0,09764879 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03705459 0,09754195 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03705459 0,09743535 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03705459 0,09732898 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03705459 0,09722284 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03705459 0,09711693 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03705459 0,09701126 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03705459 0,09690581 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03705459 0,09680059 ! lymph node development GO:0048535 10 7 0,000 0,03705459 0,0966956 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03705459 0,09659084 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03705459 0,09648631 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03705459 0,096382 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03705459 0,09627791 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03705459 0,09617405 ! adult feeding behavior GO:0008343 9 7 0,000 0,03705459 0,09607042 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03705459 0,095967 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03705459 0,09586381 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03705459 0,09576084 ! muscle adaptation GO:0043500 14 7 0,000 0,03705459 0,0956581 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03705459 0,09555557 ! retina homeostasis GO:0001895 12 7 0,000 0,03705459 0,09545326 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03705459 0,09535117 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03705459 0,0952493 ! protein prenylation GO:0018342 18 7 0,000 0,03705459 0,09514765 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03705459 0,09504621 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03705459 0,09494499 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03705459 0,09484399 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,03784307 0,09675923 ! muscle fiber development GO:0048747 112 57 1,000 0,03784307 0,09665651 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,03784307 0,09655401 ! maintenance of location GO:0051235 118 57 1,000 0,03784307 0,09645173 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,03905906 0,09944561 ! regulation of endocytosis GO:0030100 91 58 1,000 0,03905906 0,09934049 ! regulation of cellular component size GO:0032535 109 59 1,000 0,0402898 0,10236246 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,0402898 0,10225449 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,0402898 0,10214674 ! establishment of organelle localization GO:0051656 109 59 1,000 0,0402898 0,10203921 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,04153509 0,10508246 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0422355 0,10674224 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0422355 0,10663023 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0422355 0,10651846 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0422355 0,10640692 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0422355 0,10629562 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0422355 0,10618455 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0422355 0,10607371 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0422355 0,1059631 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0422355 0,10585272 ! meiotic prophase I GO:0007128 13 8 0,000 0,0422355 0,10574257 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0422355 0,10563265 ! oligopeptide transport GO:0006857 15 8 0,000 0,0422355 0,10552296 ! UTP metabolic process GO:0046051 8 8 0,000 0,0422355 0,1054135 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0422355 0,10530426 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0422355 0,10519525 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0422355 0,10508647 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0422355 0,10497791 ! succinate metabolic process GO:0006105 14 8 0,000 0,0422355 0,10486957 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0422355 0,10476146 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0422355 0,10465357 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0422355 0,1045459 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0422355 0,10443845 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0422355 0,10433122 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0422355 0,10422422 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0422355 0,10411743 ! reflex GO:0060004 16 8 0,000 0,0422355 0,10401086 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0422355 0,10390451 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0422355 0,10379838 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0422355 0,10369246 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0422355 0,10358676 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0422355 0,10348128 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0422355 0,103376 ! pigment granule organization GO:0048753 16 8 0,000 0,0422355 0,10327095 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0422355 0,1031661 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0422355 0,10306147 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0422355 0,10295705 ! histidine metabolic process GO:0006547 16 8 0,000 0,0422355 0,10285285 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0422355 0,10274885 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0422355 0,10264506 ! glycine catabolic process GO:0006546 13 8 0,000 0,0422355 0,10254149 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0422355 0,10243812 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0422355 0,10233496 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,0422355 0,102232 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0422355 0,10212926 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0422355 0,10202672 ! melanin metabolic process GO:0006582 15 8 0,000 0,0422355 0,10192439 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0422355 0,10182226 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0422355 0,10172033 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0422355 0,10161861 ! macrophage activation GO:0042116 12 8 0,000 0,0422355 0,1015171 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0422355 0,10141578 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0422355 0,10131467 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0422355 0,10121376 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0422355 0,10111305 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0422355 0,10101254 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0422355 0,10091223 ! osteoblast development GO:0002076 16 8 0,000 0,0422355 0,10081212 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0422355 0,1007122 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0422355 0,10061249 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0422355 0,10051297 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0422355 0,10041365 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0422355 0,10031452 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0422355 0,10021559 ! response to UV-B GO:0010224 16 8 0,000 0,0422355 0,10011686 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0422355 0,10001832 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0422355 0,09991997 ! intermediate filament organization GO:0045109 12 8 0,000 0,0422355 0,09982182 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0422355 0,09972386 ! cellular extravasation GO:0045123 12 8 0,000 0,0422355 0,09962609 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0422355 0,09952851 ! response to antibiotic GO:0046677 11 8 0,000 0,0422355 0,09943113 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0422355 0,09933393 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0422355 0,09923693 ! DNA topological change GO:0006265 12 8 0,000 0,0422355 0,09914011 ! response to tropane GO:0014073 15 8 0,000 0,0422355 0,09904348 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0422355 0,09894704 ! melanosome transport GO:0032402 13 8 0,000 0,0422355 0,09885079 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0422355 0,09875473 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0422355 0,09865885 ! mast cell activation GO:0045576 14 8 0,000 0,0422355 0,09856315 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0422355 0,09846765 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0422355 0,09837233 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0422355 0,09827719 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0422355 0,09818223 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0422355 0,09808746 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0422355 0,09799288 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0422355 0,09789847 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0422355 0,09780425 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0422355 0,0977102 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0422355 0,09761634 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0422355 0,09752266 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0422355 0,09742916 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0422355 0,09733584 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0422355 0,09724269 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0422355 0,09714972 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0422355 0,09705694 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0422355 0,09696432 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0422355 0,09687189 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0422355 0,09677963 ! hormone catabolic process GO:0042447 17 8 0,000 0,0422355 0,09668755 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0422355 0,09659564 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0422355 0,09650391 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0422355 0,09641235 ! ATP catabolic process GO:0006200 11 8 0,000 0,0422355 0,09632096 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0422355 0,09622975 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0422355 0,09613871 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0422355 0,09604784 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0422355 0,09595714 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0422355 0,09586662 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0422355 0,09577626 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0422355 0,09568608 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0422355 0,09559606 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0422355 0,09550621 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0422355 0,09541654 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0422355 0,09532703 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0422355 0,09523769 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0422355 0,09514851 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0422355 0,09505951 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0422355 0,09497067 ! mesoderm development GO:0007498 119 61 1,000 0,04279475 0,09613833 ! ear development GO:0043583 103 62 1,000 0,04406858 0,09890765 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,04406858 0,09881547 ! regulation of mitosis GO:0007088 105 63 1,000 0,0453564 0,10160848 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,0453564 0,10151396 ! detection of external stimulus GO:0009581 91 63 1,000 0,0453564 0,10141961 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,0453564 0,10132544 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,0453564 0,10123145 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,04665803 0,10404005 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 1,000 0,04665803 0,10394372 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,04665803 0,10384757 ! regulation of developmental growth GO:0048638 15 9 0,000 0,0473887 0,10537636 ! axon extension GO:0048675 15 9 0,000 0,0473887 0,10527906 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0473887 0,10518194 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0473887 0,105085 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0473887 0,10498824 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0473887 0,10489165 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0473887 0,10479524 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0473887 0,10469901 ! phosphate transport GO:0006817 19 9 0,000 0,0473887 0,10460296 ! reproductive behavior GO:0019098 19 9 0,000 0,0473887 0,10450708 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0473887 0,10441138 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0473887 0,10431585 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0473887 0,1042205 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0473887 0,10412532 ! GTP metabolic process GO:0046039 9 9 0,000 0,0473887 0,10403031 ! RNA methylation GO:0001510 15 9 0,000 0,0473887 0,10393548 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0473887 0,10384082 ! artery development GO:0060840 24 9 0,000 0,0473887 0,10374634 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0473887 0,10365202 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0473887 0,10355788 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0473887 0,10346391 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0473887 0,1033701 ! chemosensory behavior GO:0007635 20 9 0,000 0,0473887 0,10327647 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0473887 0,10318301 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0473887 0,10308971 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0473887 0,10299659 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0473887 0,10290363 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0473887 0,10281084 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0473887 0,10271822 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0473887 0,10262576 ! protein targeting to ER GO:0045047 22 9 0,000 0,0473887 0,10253347 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0473887 0,10244135 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0473887 0,10234939 ! T cell selection GO:0045058 23 9 0,000 0,0473887 0,1022576 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0473887 0,10216597 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0473887 0,10207451 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0473887 0,10198321 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0473887 0,10189207 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0473887 0,10180109 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0473887 0,10171028 ! mannose metabolic process GO:0006013 13 9 0,000 0,0473887 0,10161963 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0473887 0,10152914 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0473887 0,10143881 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0473887 0,10134864 ! receptor clustering GO:0043113 18 9 0,000 0,0473887 0,10125864 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0473887 0,10116879 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0473887 0,1010791 ! ruffle organization GO:0031529 15 9 0,000 0,0473887 0,10098957 ! retinol metabolic process GO:0042572 18 9 0,000 0,0473887 0,1009002 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0473887 0,10081098 ! behavioral fear response GO:0001662 22 9 0,000 0,0473887 0,10072193 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0473887 0,10063303 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0473887 0,10054429 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0473887 0,1004557 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,0473887 0,10036727 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0473887 0,100279 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0473887 0,10019088 ! segment specification GO:0007379 13 9 0,000 0,0473887 0,10010292 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0473887 0,10001511 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0473887 0,09992745 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0473887 0,09983995 ! response to amine stimulus GO:0014075 13 9 0,000 0,0473887 0,0997526 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0473887 0,09966541 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0473887 0,09957836 ! gas homeostasis GO:0033483 16 9 0,000 0,0473887 0,09949147 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0473887 0,09940473 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0473887 0,09931814 ! renal water homeostasis GO:0003091 14 9 0,000 0,0473887 0,0992317 ! postreplication repair GO:0006301 22 9 0,000 0,0473887 0,09914541 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0473887 0,09905927 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0473887 0,09897328 ! icosanoid secretion GO:0032309 15 9 0,000 0,0473887 0,09888744 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0473887 0,09880175 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0473887 0,09871621 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,0473887 0,09863082 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0473887 0,09854557 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0473887 0,09846047 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0473887 0,09837552 ! sterol catabolic process GO:0016127 11 9 0,000 0,0473887 0,09829071 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0473887 0,09820605 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0473887 0,09812153 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0473887 0,09803717 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0473887 0,09795294 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0473887 0,09786886 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0473887 0,09778493 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0473887 0,09770113 ! purine base metabolic process GO:0006144 21 9 0,000 0,0473887 0,09761749 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0473887 0,09753398 ! pigment granule transport GO:0051904 17 9 0,000 0,0473887 0,09745062 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0473887 0,0973674 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0473887 0,09728432 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0473887 0,09720138 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0473887 0,09711859 ! mitochondrion localization GO:0051646 15 9 0,000 0,0473887 0,09703593 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,04797328 0,09814941 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,05199894 0,10629519 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,05199894 0,10620496 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,05199894 0,10611488 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,05199894 0,10602495 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05251435 0,10698521 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05251435 0,1068947 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05251435 0,10680434 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05251435 0,10671413 ! synapsis GO:0007129 13 10 0,000 0,05251435 0,10662408 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05251435 0,10653418 ! N-glycan processing GO:0006491 20 10 0,000 0,05251435 0,10644443 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05251435 0,10635483 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05251435 0,10626538 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05251435 0,10617608 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05251435 0,10608693 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05251435 0,10599793 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05251435 0,10590908 ! androgen metabolic process GO:0008209 17 10 0,000 0,05251435 0,10582038 ! phospholipid efflux GO:0033700 16 10 0,000 0,05251435 0,10573183 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05251435 0,10564342 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05251435 0,10555517 ! lung alveolus development GO:0048286 26 10 0,000 0,05251435 0,10546706 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05251435 0,10537909 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05251435 0,10529128 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05251435 0,10520361 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05251435 0,10511608 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05251435 0,10502871 ! endoderm development GO:0007492 16 10 0,000 0,05251435 0,10494147 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05251435 0,10485439 ! arginine catabolic process GO:0006527 13 10 0,000 0,05251435 0,10476744 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05251435 0,10468064 ! proline metabolic process GO:0006560 13 10 0,000 0,05251435 0,10459399 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05251435 0,10450747 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05251435 0,1044211 ! V(D)J recombination GO:0033151 28 10 0,000 0,05251435 0,10433488 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05251435 0,10424879 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05251435 0,10416285 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05251435 0,10407705 ! B cell proliferation GO:0042100 18 10 0,000 0,05251435 0,10399139 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05251435 0,10390587 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05251435 0,10382049 ! multicellular organism growth GO:0035264 18 10 0,000 0,05251435 0,10373525 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05251435 0,10365015 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05251435 0,10356519 ! epithelial cell development GO:0002064 20 10 0,000 0,05251435 0,10348037 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05251435 0,10339569 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05251435 0,10331115 ! macroautophagy GO:0016236 17 10 0,000 0,05251435 0,10322674 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05251435 0,10314248 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05251435 0,10305835 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05251435 0,10297436 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05251435 0,1028905 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05251435 0,10280678 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05251435 0,1027232 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05251435 0,10263975 ! brain morphogenesis GO:0048854 23 10 0,000 0,05251435 0,10255644 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05251435 0,10247326 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05251435 0,10239022 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05251435 0,10230732 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05251435 0,10222454 ! response to dsRNA GO:0043331 20 10 0,000 0,05251435 0,1021419 ! DNA ligation GO:0006266 19 10 0,000 0,05251435 0,1020594 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05251435 0,10197703 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05251435 0,10189479 ! melanosome localization GO:0032400 16 10 0,000 0,05251435 0,10181268 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05251435 0,1017307 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05251435 0,10164886 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05251435 0,10156715 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05251435 0,10148557 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05251435 0,10140412 ! mRNA cleavage GO:0006379 17 10 0,000 0,05251435 0,1013228 ! protein sumoylation GO:0016925 15 10 0,000 0,05251435 0,10124161 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05251435 0,10116056 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05251435 0,10107963 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05251435 0,10099883 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05251435 0,10091816 ! salivary gland development GO:0007431 27 10 0,000 0,05251435 0,10083762 ! prophase GO:0051324 15 10 0,000 0,05251435 0,1007572 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05251435 0,10067692 ! apical protein localization GO:0045176 15 10 0,000 0,05251435 0,10059676 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05251435 0,10051673 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05251435 0,10043683 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05251435 0,10035706 ! midbrain development GO:0030901 13 10 0,000 0,05251435 0,10027741 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05251435 0,10019789 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05251435 0,10011849 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05251435 0,10003922 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05251435 0,09996007 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05251435 0,09988105 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05251435 0,09980216 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05251435 0,09972339 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05251435 0,09964474 ! oocyte development GO:0048599 17 10 0,000 0,05251435 0,09956622 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05251435 0,09948782 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05251435 0,09940955 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05251435 0,09933139 ! activation of innate immune response GO:0002218 12 10 0,000 0,05251435 0,09925337 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05251435 0,09917546 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05251435 0,09909767 ! response to nicotine GO:0035094 20 10 0,000 0,05251435 0,09902001 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05251435 0,09894247 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05251435 0,09886505 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05251435 0,09878775 ! localization within membrane GO:0051668 20 10 0,000 0,05251435 0,09871057 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,05336686 0,10023472 ! appendage morphogenesis GO:0035107 135 70 1,000 0,05474752 0,10274768 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 1,000 0,05614072 0,10528026 ! appendage development GO:0048736 136 71 1,000 0,05614072 0,10519826 GO:0060173|limb development, ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0575463 0,10774817 ! carbohydrate transport GO:0008643 110 72 1,000 0,0575463 0,10766439 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,0575463 0,10758073 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,0575463 0,1074972 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05761259 0,10753755 ! respiratory burst GO:0045730 17 11 0,000 0,05761259 0,10745418 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05761259 0,10737095 ! neuron fate specification GO:0048665 17 11 0,000 0,05761259 0,10728785 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05761259 0,10720487 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05761259 0,10712202 ! thyroid gland development GO:0030878 26 11 0,000 0,05761259 0,1070393 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,05761259 0,10695671 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05761259 0,10687425 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05761259 0,10679191 ! response to pain GO:0048265 24 11 0,000 0,05761259 0,1067097 ! T cell proliferation GO:0042098 26 11 0,000 0,05761259 0,10662761 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05761259 0,10654565 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05761259 0,10646382 ! bone resorption GO:0045453 16 11 0,000 0,05761259 0,10638212 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,05761259 0,10630053 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05761259 0,10621908 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05761259 0,10613775 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05761259 0,10605654 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05761259 0,10597546 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05761259 0,1058945 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05761259 0,10581366 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05761259 0,10573295 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05761259 0,10565236 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05761259 0,10557189 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05761259 0,10549155 ! lipid digestion GO:0044241 18 11 0,000 0,05761259 0,10541133 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05761259 0,10533123 ! UV protection GO:0009650 19 11 0,000 0,05761259 0,10525125 ! adult heart development GO:0007512 14 11 0,000 0,05761259 0,10517139 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05761259 0,10509166 ! temperature homeostasis GO:0001659 17 11 0,000 0,05761259 0,10501204 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05761259 0,10493255 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05761259 0,10485317 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05761259 0,10477392 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05761259 0,10469479 ! regulation of organ growth GO:0046620 13 11 0,000 0,05761259 0,10461577 ! pigment granule localization GO:0051875 20 11 0,000 0,05761259 0,10453688 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05761259 0,1044581 ! vasoconstriction GO:0042310 18 11 0,000 0,05761259 0,10437944 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05761259 0,1043009 ! embryonic axis specification GO:0000578 18 11 0,000 0,05761259 0,10422248 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05761259 0,10414417 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05761259 0,10406599 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05761259 0,10398792 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05761259 0,10390997 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05761259 0,10383213 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05761259 0,10375441 ! zymogen activation GO:0031638 15 11 0,000 0,05761259 0,10367681 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05761259 0,10359932 ! nucleosome positioning GO:0016584 15 11 0,000 0,05761259 0,10352195 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05761259 0,1034447 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05761259 0,10336756 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05761259 0,10329053 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05761259 0,10321362 ! acid secretion GO:0046717 18 11 0,000 0,05761259 0,10313683 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05761259 0,10306015 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05761259 0,10298358 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05761259 0,10290712 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05761259 0,10283078 ! oocyte differentiation GO:0009994 18 11 0,000 0,05761259 0,10275456 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05761259 0,10267844 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05761259 0,10260244 ! cholesterol efflux GO:0033344 19 11 0,000 0,05761259 0,10252655 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05761259 0,10245077 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05761259 0,10237511 ! germ cell migration GO:0008354 25 11 0,000 0,05761259 0,10229955 ! embryonic gut development GO:0048566 15 11 0,000 0,05761259 0,10222411 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05761259 0,10214878 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05761259 0,10207356 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05761259 0,10199845 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05761259 0,10192345 ! defense response to fungus GO:0050832 13 11 0,000 0,05761259 0,10184856 ! developmental induction GO:0031128 19 11 0,000 0,05761259 0,10177379 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05761259 0,10169912 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05761259 0,10162456 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05761259 0,10155011 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05761259 0,10147577 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05761259 0,10140153 ! regulation of embryonic development GO:0045995 27 11 0,000 0,05761259 0,10132741 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05761259 0,10125339 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,05896409 0,10355299 ! axon guidance GO:0007411 139 73 1,000 0,05896409 0,10347746 ! fertilization GO:0009566 90 73 1,000 0,05896409 0,10340204 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,06039391 0,1058323 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,06039391 0,10575528 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,06039391 0,10567836 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,0618356 0,10812243 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,0618356 0,10804391 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,0618356 0,1079655 ! meiotic cell cycle GO:0051321 122 75 1,000 0,0618356 0,10788721 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06268357 0,10928744 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06268357 0,1092083 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06268357 0,10912928 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06268357 0,10905037 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06268357 0,10897158 ! virus-host interaction GO:0019048 29 12 0,000 0,06268357 0,1088929 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06268357 0,10881433 ! cartilage condensation GO:0001502 20 12 0,000 0,06268357 0,10873588 ! mating GO:0007618 17 12 0,000 0,06268357 0,10865754 ! protein complex disassembly GO:0043241 27 12 0,000 0,06268357 0,10857931 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06268357 0,1085012 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06268357 0,10842319 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06268357 0,1083453 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06268357 0,10826752 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06268357 0,10818986 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06268357 0,1081123 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06268357 0,10803486 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06268357 0,10795752 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06268357 0,1078803 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06268357 0,10780319 ! drug transport GO:0015893 16 12 0,000 0,06268357 0,10772619 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06268357 0,10764929 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06268357 0,10757251 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06268357 0,10749584 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06268357 0,10741927 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06268357 0,10734282 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06268357 0,10726647 ! forebrain cell migration GO:0021885 21 12 0,000 0,06268357 0,10719024 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06268357 0,10711411 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06268357 0,10703808 ! entry into host cell GO:0030260 32 12 0,000 0,06268357 0,10696217 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06268357 0,10688637 ! monoamine transport GO:0015844 18 12 0,000 0,06268357 0,10681067 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06268357 0,10673508 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06268357 0,10665959 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06268357 0,10658421 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06268357 0,10650894 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06268357 0,10643378 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06268357 0,10635872 ! protein homotetramerization GO:0051289 21 12 0,000 0,06268357 0,10628376 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06268357 0,10620892 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06268357 0,10613417 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06268357 0,10605954 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06268357 0,105985 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06268357 0,10591058 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06268357 0,10583625 ! cranial nerve development GO:0021545 20 12 0,000 0,06268357 0,10576203 ! fucose catabolic process GO:0019317 22 12 0,000 0,06268357 0,10568792 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06268357 0,10561391 ! histone acetylation GO:0016573 26 12 0,000 0,06268357 0,10554 ! histone methylation GO:0016571 26 12 0,000 0,06268357 0,1054662 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06268357 0,1053925 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06268357 0,1053189 ! gland morphogenesis GO:0022612 29 12 0,000 0,06268357 0,1052454 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06268357 0,10517201 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06268357 0,10509872 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06268357 0,10502553 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06268357 0,10495244 ! spleen development GO:0048536 22 12 0,000 0,06268357 0,10487946 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06268357 0,10480657 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06268357 0,10473379 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06268357 0,10466111 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06268357 0,10458853 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06268357 0,10451605 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06268357 0,10444367 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06268357 0,10437139 ! response to cold GO:0009409 17 12 0,000 0,06268357 0,10429921 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06268357 0,10422713 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06268357 0,10415515 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,06475392 0,107521 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,06475392 0,10744685 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06475392 0,1073728 ! blood coagulation GO:0007596 146 78 1,000 0,06623022 0,10974511 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,06623022 0,10966958 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,06771772 0,11205559 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,06771772 0,11197858 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06772742 0,1119177 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06772742 0,11184089 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06772742 0,11176418 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06772742 0,11168758 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06772742 0,11161108 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06772742 0,11153469 ! lipid localization GO:0010876 28 13 0,000 0,06772742 0,1114584 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,06772742 0,11138221 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06772742 0,11130613 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06772742 0,11123016 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06772742 0,11115428 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06772742 0,11107851 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06772742 0,11100285 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06772742 0,11092728 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06772742 0,11085182 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06772742 0,11077646 ! methionine metabolic process GO:0006555 27 13 0,000 0,06772742 0,11070121 ! plasma membrane organization GO:0007009 24 13 0,000 0,06772742 0,11062605 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06772742 0,110551 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06772742 0,11047605 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06772742 0,1104012 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! response to X-ray GO:0010165 25 13 0,000 0,06772742 0,11032646 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06772742 0,11025181 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06772742 0,11017727 ! exocrine system development GO:0035272 32 13 0,000 0,06772742 0,11010282 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,06772742 0,11002848 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06772742 0,10995424 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06772742 0,10988009 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06772742 0,10980605 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06772742 0,10973211 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06772742 0,10965826 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06772742 0,10958452 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06772742 0,10951087 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06772742 0,10943733 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06772742 0,10936388 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06772742 0,10929053 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06772742 0,10921728 ! ribosome assembly GO:0042255 17 13 0,000 0,06772742 0,10914412 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,06772742 0,10907107 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06772742 0,10899811 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06772742 0,10892525 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06772742 0,10885249 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06772742 0,10877982 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06772742 0,10870726 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06772742 0,10863478 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06772742 0,10856241 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06772742 0,10849013 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06772742 0,10841795 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06772742 0,10834586 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06772742 0,10827387 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06772742 0,10820198 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06772742 0,10813018 ! insulin secretion GO:0030073 23 13 0,000 0,06772742 0,10805847 ! actin filament polymerization GO:0030041 24 13 0,000 0,06772742 0,10798686 ! acrosome reaction GO:0007340 18 13 0,000 0,06772742 0,10791535 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,06921627 0,11021465 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,0707257 0,11254368 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,0707257 0,11246929 ! rRNA transcription GO:0009303 25 14 0,000 0,0727443 0,1156029 ! lactation GO:0007595 26 14 0,000 0,0727443 0,11552659 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0727443 0,11545039 ! reproductive cellular process GO:0048610 20 14 0,000 0,0727443 0,11537429 ! tRNA modification GO:0006400 20 14 0,000 0,0727443 0,11529828 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0727443 0,11522238 ! regulation of S phase GO:0033261 23 14 0,000 0,0727443 0,11514657 ! water transport GO:0006833 21 14 0,000 0,0727443 0,11507087 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0727443 0,11499526 ! non-recombinational repair GO:0000726 25 14 0,000 0,0727443 0,11491976 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0727443 0,11484435 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0727443 0,11476904 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0727443 0,11469383 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0727443 0,11461872 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0727443 0,11454371 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0727443 0,1144688 ! palate development GO:0060021 31 14 0,000 0,0727443 0,11439398 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0727443 0,11431926 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0727443 0,11424464 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0727443 0,11417012 ! arginine metabolic process GO:0006525 17 14 0,000 0,0727443 0,11409569 ! regulation of heart rate GO:0002027 24 14 0,000 0,0727443 0,11402136 ! organic alcohol transport GO:0015850 29 14 0,000 0,0727443 0,11394713 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0727443 0,11387299 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0727443 0,11379895 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0727443 0,11372501 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 26 14 0,000 0,0727443 0,11365116 ! L-amino acid transport GO:0015807 30 14 0,000 0,0727443 0,11357741 ! bone mineralization GO:0030282 17 14 0,000 0,0727443 0,11350376 ! stem cell development GO:0048864 43 14 0,000 0,0727443 0,11343019 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0727443 0,11335673 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0727443 0,11328336 ! cerebellum development GO:0021549 21 14 0,000 0,0727443 0,11321008 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0727443 0,1131369 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0727443 0,11306382 ! response to gamma radiation GO:0010332 28 14 0,000 0,0727443 0,11299083 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0727443 0,11291793 ! cofactor transport GO:0051181 26 14 0,000 0,0727443 0,11284513 ! NADP metabolic process GO:0006739 24 14 0,000 0,0727443 0,11277242 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0727443 0,1126998 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0727443 0,11262728 ! intestinal absorption GO:0050892 25 14 0,000 0,0727443 0,11255485 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0727443 0,11248251 ! oxygen transport GO:0015671 21 14 0,000 0,0727443 0,11241027 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0727443 0,11233812 ! male genitalia development GO:0030539 24 14 0,000 0,0727443 0,11226606 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0727443 0,1121941 ! regulation of axon extension GO:0030516 37 14 0,000 0,0727443 0,11212222 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0727443 0,11205044 ! hemostasis GO:0007599 158 84 1,000 0,07531774 0,11594016 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,07531774 0,11586603 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,07686914 0,11817709 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,07686914 0,11810163 GO:0002696|positive regulation of leukocyte activation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07773435 0,11935472 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07773435 0,1192786 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07773435 0,11920258 ! superoxide anion generation GO:0042554 20 15 0,000 0,07773435 0,11912665 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07773435 0,11905083 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07773435 0,11897509 ! copper ion transport GO:0006825 20 15 0,000 0,07773435 0,11889946 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07773435 0,11882392 ! sulfate transport GO:0008272 23 15 0,000 0,07773435 0,11874847 ! response to cAMP GO:0051591 22 15 0,000 0,07773435 0,11867313 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07773435 0,11859787 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07773435 0,11852272 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07773435 0,11844765 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07773435 0,11837269 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07773435 0,11829782 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07773435 0,11822304 ! pituitary gland development GO:0021983 29 15 0,000 0,07773435 0,11814836 ! vesicle coating GO:0006901 33 15 0,000 0,07773435 0,11807377 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07773435 0,11799927 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07773435 0,11792487 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07773435 0,11785057 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07773435 0,11777635 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07773435 0,11770223 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07773435 0,11762821 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07773435 0,11755427 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07773435 0,11748043 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07773435 0,11740668 ! histone deacetylation GO:0016575 20 15 0,000 0,07773435 0,11733303 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07773435 0,11725947 ! tissue regeneration GO:0042246 26 15 0,000 0,07773435 0,11718599 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07773435 0,11711262 ! water homeostasis GO:0030104 27 15 0,000 0,07773435 0,11703933 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07773435 0,11696613 ! muscle maintenance GO:0046716 26 15 0,000 0,07773435 0,11689303 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07773435 0,11682002 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07773435 0,1167471 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07773435 0,11667426 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07773435 0,11660153 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07773435 0,11652888 ! cell killing GO:0001906 29 15 0,000 0,07773435 0,11645632 ! detection of bacterium GO:0016045 18 15 0,000 0,07773435 0,11638385 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07773435 0,11631147 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07773435 0,11623918 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07773435 0,11616699 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07773435 0,11609488 ! peptide hormone processing GO:0016486 23 15 0,000 0,07773435 0,11602286 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,08000211 0,11933358 ! regulation of protein transport GO:0051223 154 87 1,000 0,08000211 0,11925965 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 1,000 0,08158337 0,12154154 ! regulation of DNA binding GO:0051101 155 88 1,000 0,08158337 0,12146633 ! gland development GO:0048732 206 88 1,000 0,08158337 0,12139121 ! regulation of neurological system process GO:0031644 148 88 1,000 0,08158337 0,12131619 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08269771 0,12289728 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08269771 0,12282141 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08269771 0,12274564 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08269771 0,12266997 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08269771 0,12259439 ! bone remodeling GO:0046849 27 16 0,000 0,08269771 0,1225189 ! filopodium assembly GO:0046847 32 16 0,000 0,08269771 0,1224435 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08269771 0,1223682 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08269771 0,12229299 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08269771 0,12221787 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08269771 0,12214284 ! startle response GO:0001964 28 16 0,000 0,08269771 0,12206791 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08269771 0,12199306 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08269771 0,12191831 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08269771 0,12184366 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08269771 0,12176909 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08269771 0,12169461 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08269771 0,12162023 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08269771 0,12154593 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08269771 0,12147173 ! response to osmotic stress GO:0006970 25 16 0,000 0,08269771 0,12139761 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08269771 0,12132359 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08269771 0,12124966 ! fructose metabolic process GO:0006000 25 16 0,000 0,08269771 0,12117582 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08269771 0,12110206 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08269771 0,1210284 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08269771 0,12095483 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08269771 0,12088134 ! axon cargo transport GO:0008088 43 16 0,000 0,08269771 0,12080795 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08269771 0,12073464 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08269771 0,12066142 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08269771 0,1205883 ! neuron recognition GO:0008038 35 16 0,000 0,08269771 0,12051526 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08269771 0,12044231 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08269771 0,12036944 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08269771 0,12029667 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08269771 0,12022398 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08269771 0,12015138 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08269771 0,12007887 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08269771 0,12000645 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08269771 0,11993411 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08269771 0,11986186 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08269771 0,1197897 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08269771 0,11971762 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08269771 0,11964563 ! defense response to virus GO:0051607 37 16 0,000 0,08269771 0,11957373 ! ossification GO:0001503 188 90 1,000 0,08477471 0,12250328 ! bone development GO:0060348 189 91 1,000 0,08638449 0,12475455 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08763452 0,1264839 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08763452 0,12640807 ! metencephalon development GO:0022037 30 17 0,000 0,08763452 0,12633233 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08763452 0,12625668 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08763452 0,12618112 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08763452 0,12610566 ! signal complex assembly GO:0007172 41 17 0,000 0,08763452 0,12603028 ! endothelial cell migration GO:0043542 28 17 0,000 0,08763452 0,12595499 ! inositol metabolic process GO:0006020 28 17 0,000 0,08763452 0,1258798 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08763452 0,12580469 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08763452 0,12572967 ! glial cell development GO:0021782 27 17 0,000 0,08763452 0,12565474 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08763452 0,1255799 ! adult walking behavior GO:0007628 33 17 0,000 0,08763452 0,12550515 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08763452 0,12543049 ! heart looping GO:0001947 30 17 0,000 0,08763452 0,12535592 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08763452 0,12528144 ! myoblast differentiation GO:0045445 45 17 0,000 0,08763452 0,12520704 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08763452 0,12513273 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,08763452 0,12505852 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,08763452 0,12498439 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08763452 0,12491034 ! glycine metabolic process GO:0006544 28 17 0,000 0,08763452 0,12483639 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,08763452 0,12476252 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08763452 0,12468874 ! NAD metabolic process GO:0019674 29 17 0,000 0,08763452 0,12461505 ! membrane budding GO:0006900 37 17 0,000 0,08763452 0,12454144 ! DNA integration GO:0015074 29 17 0,000 0,08763452 0,12446792 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,08763452 0,12439449 ! regulation of protein binding GO:0043393 33 17 0,000 0,08763452 0,12432114 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08763452 0,12424788 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08763452 0,12417471 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08763452 0,12410162 ! genitalia development GO:0048806 30 17 0,000 0,08763452 0,12402862 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08763452 0,12395571 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08763452 0,12388288 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08763452 0,12381013 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08763452 0,12373748 ! steroid catabolic process GO:0006706 31 17 0,000 0,08763452 0,1236649 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08763452 0,12359241 ! gas transport GO:0015669 25 17 0,000 0,08763452 0,12352001 ! organic cation transport GO:0015695 31 17 0,000 0,08763452 0,12344769 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08763452 0,12337546 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,08763452 0,12330331 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08763452 0,12323124 ! microspike assembly GO:0030035 36 17 0,000 0,08763452 0,12315926 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,08763452 0,12308737 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,08763452 0,12301555 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,08963155 0,12574548 GO:0010498|proteasomal protein catabolic process, ! transcription initiation GO:0006352 153 94 1,000 0,09126854 0,12796743 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09254493 0,12968148 ! neuron maturation GO:0042551 42 18 0,000 0,09254493 0,12960599 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09254493 0,1295306 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09254493 0,12945529 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09254493 0,12938007 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09254493 0,12930493 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09254493 0,12922989 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09254493 0,12915493 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09254493 0,12908005 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09254493 0,12900527 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09254493 0,12893057 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09254493 0,12885596 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09254493 0,12878143 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09254493 0,12870699 ! response to retinoic acid GO:0032526 26 18 0,000 0,09254493 0,12863264 ! response to fungus GO:0009620 21 18 0,000 0,09254493 0,12855837 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09254493 0,12848419 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09254493 0,12841009 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09254493 0,12833608 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09254493 0,12826215 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09254493 0,12818831 ! vitamin transport GO:0051180 27 18 0,000 0,09254493 0,12811455 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09254493 0,12804088 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09254493 0,1279673 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09254493 0,12789379 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09254493 0,12782038 ! nerve development GO:0021675 28 18 0,000 0,09254493 0,12774704 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09254493 0,12767379 ! detection of stimulus GO:0051606 151 96 1,000 0,09456873 0,13039104 ! regulation of protein localization GO:0032880 176 97 1,000 0,09623165 0,13260787 ! protein secretion GO:0009306 39 19 0,000 0,09742907 0,13418107 ! positive regulation of translation GO:0045727 30 19 0,000 0,09742907 0,13410431 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09742907 0,13402764 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09742907 0,13395105 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09742907 0,13387455 ! skin development GO:0043588 36 19 0,000 0,09742907 0,13379814 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09742907 0,13372181 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09742907 0,13364557 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09742907 0,13356942 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09742907 0,13349336 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09742907 0,13341738 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09742907 0,13334149 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09742907 0,13326568 ! heme metabolic process GO:0042168 36 19 0,000 0,09742907 0,13318996 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09742907 0,13311433 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,09742907 0,13303878 ! peptide cross-linking GO:0018149 37 19 0,000 0,09742907 0,13296332 ! protein export from nucleus GO:0006611 36 19 0,000 0,09742907 0,13288794 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09742907 0,13281265 ! visual learning GO:0008542 36 19 0,000 0,09742907 0,13273745 ! cellular pigmentation GO:0033059 36 19 0,000 0,09742907 0,13266233 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09742907 0,13258729 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09742907 0,13251234 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09742907 0,13243748 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09742907 0,1323627 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09742907 0,132288 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09742907 0,13221339 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09742907 0,13213886 ! cilium assembly GO:0042384 37 19 0,000 0,09742907 0,13206441 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09742907 0,13199005 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,09958246 0,1348314 GO:0060538|skeletal muscle organ development, ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10228708 0,13841547 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10228708 0,13833767 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10228708 0,13825995 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10228708 0,13818232 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10228708 0,13810478 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,10228708 0,13802732 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,10228708 0,13794995 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10228708 0,13787267 ! response to vitamin GO:0033273 31 20 0,000 0,10228708 0,13779547 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10228708 0,13771836 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,10228708 0,13764134 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10228708 0,1375644 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10228708 0,13748755 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10228708 0,13741078 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10228708 0,1373341 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10228708 0,13725751 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10228708 0,137181 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10228708 0,13710458 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,10228708 0,13702824 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,10228708 0,13695198 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10228708 0,13687581 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10228708 0,13679973 ! body fluid secretion GO:0007589 31 20 0,000 0,10228708 0,13672373 ! peptide secretion GO:0002790 35 20 0,000 0,10228708 0,13664781 ! stem cell differentiation GO:0048863 53 20 0,000 0,10228708 0,13657198 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10228708 0,13649624 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10228708 0,13642057 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10228708 0,13634499 ! sensory perception of pain GO:0019233 30 20 0,000 0,10228708 0,1362695 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10228708 0,13619409 ! diencephalon development GO:0021536 34 20 0,000 0,10228708 0,13611876 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10228708 0,13604351 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10228708 0,13596835 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10228708 0,13589327 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10228708 0,13581828 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10228708 0,13574336 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10228708 0,13566853 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10228708 0,13559378 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10228708 0,13551912 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10228708 0,13544453 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10228708 0,13537003 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10228708 0,13529561 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10228708 0,13522127 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10228708 0,13514702 ! regulation of cell killing GO:0031341 42 21 0,000 0,10711911 0,14145366 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10711911 0,14137607 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10711911 0,14129856 ! hormone secretion GO:0046879 38 21 0,000 0,10711911 0,14122113 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10711911 0,14114379 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10711911 0,14106654 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10711911 0,14098937 ! axis specification GO:0009798 38 21 0,000 0,10711911 0,14091229 ! ovarian follicle development GO:0001541 35 21 0,000 0,10711911 0,14083528 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10711911 0,14075837 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10711911 0,14068153 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10711911 0,14060478 ! cell aging GO:0007569 44 21 0,000 0,10711911 0,14052812 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10711911 0,14045154 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10711911 0,14037504 ! cytolysis GO:0019835 24 21 0,000 0,10711911 0,14029862 ! vasodilation GO:0042311 39 21 0,000 0,10711911 0,14022229 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10711911 0,14014604 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10711911 0,14006987 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10711911 0,13999379 ! oogenesis GO:0048477 36 21 0,000 0,10711911 0,13991779 ! DNA modification GO:0006304 34 21 0,000 0,10711911 0,13984187 ! collagen fibril organization GO:0030199 59 21 0,000 0,10711911 0,13976604 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10711911 0,13969028 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10711911 0,13961461 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10711911 0,13953902 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10711911 0,13946351 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10711911 0,13938809 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10711911 0,13931274 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10711911 0,13923748 ! collagen catabolic process GO:0030574 28 21 0,000 0,10711911 0,13916229 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10711911 0,13908719 ! gut development GO:0048565 39 21 0,000 0,10711911 0,13901217 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11192528 0,14517101 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11192528 0,1450928 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11192528 0,14501466 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11192528 0,14493662 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11192528 0,14485865 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11192528 0,14478077 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11192528 0,14470297 ! regeneration GO:0031099 41 22 0,000 0,11192528 0,14462526 ! keratinization GO:0031424 28 22 0,000 0,11192528 0,14454763 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11192528 0,14447008 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11192528 0,14439262 ! sensory perception of taste GO:0050909 28 22 0,000 0,11192528 0,14431524 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,11192528 0,14423794 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11192528 0,14416072 ! vacuolar transport GO:0007034 36 22 0,000 0,11192528 0,14408359 ! lysosome organization GO:0007040 41 22 0,000 0,11192528 0,14400654 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11192528 0,14392957 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11192528 0,14385269 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11192528 0,14377588 ! fucose metabolic process GO:0006004 39 22 0,000 0,11192528 0,14369916 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11192528 0,14362252 ! ureteric bud development GO:0001657 43 22 0,000 0,11192528 0,14354597 ! renal system process GO:0003014 41 22 0,000 0,11192528 0,14346949 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11192528 0,14339309 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,11192528 0,14331678 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11192528 0,14324055 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11192528 0,1431644 ! sarcomere organization GO:0045214 30 22 0,000 0,11192528 0,14308833 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11192528 0,14301234 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11192528 0,14293643 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11192528 0,1428606 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11192528 0,14278485 ! protein stabilization GO:0050821 39 22 0,000 0,11192528 0,14270918 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,11670575 0,14872565 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11670575 0,14864692 ! gluconeogenesis GO:0006094 33 23 0,000 0,11670575 0,14856827 ! viral genome replication GO:0019079 41 23 0,000 0,11670575 0,1484897 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11670575 0,14841122 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11670575 0,14833282 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11670575 0,1482545 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11670575 0,14817627 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11670575 0,14809812 ! visual behavior GO:0007632 42 23 0,000 0,11670575 0,14802005 ! response to ethanol GO:0045471 46 23 0,000 0,11670575 0,14794206 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11670575 0,14786416 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11670575 0,14778633 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11670575 0,14770859 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11670575 0,14763093 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11670575 0,14755335 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11670575 0,14747586 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,11670575 0,14739844 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,11670575 0,14732111 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11670575 0,14724385 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11670575 0,14716668 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11670575 0,14708959 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11670575 0,14701258 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11670575 0,14693565 ! fatty acid transport GO:0015908 44 23 0,000 0,11670575 0,1468588 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11670575 0,14678203 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11670575 0,14670535 ! hormone transport GO:0009914 40 23 0,000 0,11670575 0,14662874 ! cell-cell recognition GO:0009988 25 23 0,000 0,11670575 0,14655221 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11670575 0,14647576 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11670575 0,14639939 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11670575 0,1463231 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11670575 0,14624689 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12146064 0,15212613 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,12146064 0,15204698 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12146064 0,15196791 ! vesicle docking GO:0048278 47 24 0,000 0,12146064 0,15188893 ! spinal cord development GO:0021510 47 24 0,000 0,12146064 0,15181002 ! vacuole organization GO:0007033 43 24 0,000 0,12146064 0,1517312 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12146064 0,15165246 ! digestive system process GO:0022600 39 24 0,000 0,12146064 0,15157381 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12146064 0,15149523 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,12146064 0,15141673 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12146064 0,15133832 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,12146064 0,15125999 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12146064 0,15118174 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12146064 0,15110357 ! membrane depolarization GO:0051899 39 24 0,000 0,12146064 0,15102548 ! pentose metabolic process GO:0019321 35 24 0,000 0,12146064 0,15094747 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,12146064 0,15086954 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12146064 0,15079169 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12146064 0,15071392 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12146064 0,15063624 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12146064 0,15055863 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12146064 0,1504811 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12146064 0,15040365 ! regulation of amine transport GO:0051952 40 24 0,000 0,12146064 0,15032628 ! protein tetramerization GO:0051262 52 24 0,000 0,12146064 0,150249 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12619009 0,1560192 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12619009 0,15593906 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12619009 0,15585901 ! phototransduction GO:0007602 33 25 0,000 0,12619009 0,15577904 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12619009 0,15569916 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,12619009 0,15561935 ! sperm motility GO:0030317 31 25 0,000 0,12619009 0,15553963 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12619009 0,15545999 ! receptor metabolic process GO:0043112 46 25 0,000 0,12619009 0,15538043 ! chromosome condensation GO:0030261 45 25 0,000 0,12619009 0,15530095 ! response to starvation GO:0042594 42 25 0,000 0,12619009 0,15522155 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12619009 0,15514224 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,12619009 0,155063 ! neural crest cell development GO:0014032 54 25 0,000 0,12619009 0,15498385 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12619009 0,15490477 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12619009 0,15482578 ! interaction with host GO:0051701 62 25 0,000 0,12619009 0,15474687 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12619009 0,15466804 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12619009 0,15458929 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,12619009 0,15451061 ! immunoglobulin production GO:0002377 55 25 0,000 0,12619009 0,15443202 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12619009 0,15435351 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12619009 0,15427508 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12619009 0,15419673 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,12619009 0,15411846 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12619009 0,15404026 ! telomere organization GO:0032200 43 25 0,000 0,12619009 0,15396215 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12619009 0,15388411 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12619009 0,15380616 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13089424 0,15945901 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13089424 0,15937831 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13089424 0,15929769 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13089424 0,15921716 ! initiation of viral infection GO:0019059 57 26 0,000 0,13089424 0,1591367 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13089424 0,15905633 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13089424 0,15897604 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13089424 0,15889583 ! molting cycle process GO:0022404 50 26 0,000 0,13089424 0,1588157 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,13089424 0,15873565 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13089424 0,15865569 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13089424 0,1585758 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,13089424 0,15849599 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13089424 0,15841627 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13089424 0,15833662 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13089424 0,15825705 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13089424 0,15817757 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13089424 0,15809816 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13089424 0,15801883 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13089424 0,15793959 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13089424 0,15786042 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13089424 0,15778133 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13089424 0,15770232 ! neuron fate commitment GO:0048663 48 27 0,000 0,13557322 0,16325784 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,13557322 0,16317617 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13557322 0,16309458 ! iron ion transport GO:0006826 59 27 0,000 0,13557322 0,16301307 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13557322 0,16293165 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13557322 0,1628503 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13557322 0,16276904 ! fat cell differentiation GO:0045444 50 27 0,000 0,13557322 0,16268786 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13557322 0,16260676 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,13557322 0,16252574 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13557322 0,1624448 ! autophagy GO:0006914 41 27 0,000 0,13557322 0,16236394 ! male gonad development GO:0008584 44 27 0,000 0,13557322 0,16228316 ! response to toxin GO:0009636 47 27 0,000 0,13557322 0,16220247 ! primary neural tube formation GO:0014020 51 27 0,000 0,13557322 0,16212185 ! base-excision repair GO:0006284 41 27 0,000 0,13557322 0,16204131 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13557322 0,16196085 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13557322 0,16188048 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13557322 0,16180018 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13557322 0,16171996 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13557322 0,16163982 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14022716 0,16710577 ! circadian rhythm GO:0007623 50 28 0,000 0,14022716 0,16702304 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14022716 0,1669404 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14022716 0,16685784 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14022716 0,16677536 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,14022716 0,16669296 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14022716 0,16661064 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14022716 0,1665284 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14022716 0,16644625 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14022716 0,16636417 ! synaptogenesis GO:0007416 42 28 0,000 0,14022716 0,16628218 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14022716 0,16620027 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14022716 0,16611844 ! translational initiation GO:0006413 65 29 0,000 0,1448562 0,17151772 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,1448562 0,17143336 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1448562 0,17134907 ! regulation of pH GO:0006885 43 29 0,000 0,1448562 0,17126487 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1448562 0,17118075 ! catechol metabolic process GO:0009712 54 29 0,000 0,1448562 0,17109672 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,1448562 0,17101276 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,1448562 0,17092889 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,1448562 0,17084511 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,1448562 0,1707614 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,1448562 0,17067777 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,1448562 0,17059423 ! detection of light stimulus GO:0009583 38 29 0,000 0,1448562 0,17051077 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,1448562 0,17042739 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,1448562 0,17034409 ! tissue homeostasis GO:0001894 48 29 0,000 0,1448562 0,17026088 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,1448562 0,17017774 ! phenol metabolic process GO:0018958 55 30 0,000 0,14946047 0,17550117 ! zinc ion transport GO:0006829 45 30 0,000 0,14946047 0,17541556 ! membrane docking GO:0022406 61 30 0,000 0,14946047 0,17533003 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14946047 0,17524459 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14946047 0,17515923 ! acute-phase response GO:0006953 49 30 0,000 0,14946047 0,17507395 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14946047 0,17498875 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14946047 0,17490364 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,14946047 0,17481861 ! phospholipid transport GO:0015914 51 30 0,000 0,14946047 0,17473367 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14946047 0,17464881 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14946047 0,17456402 ! eye morphogenesis GO:0048592 60 30 0,000 0,14946047 0,17447933 ! response to heat GO:0009408 50 30 0,000 0,14946047 0,17439471 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1540401 0,17965123 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,1540401 0,17956419 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1540401 0,17947723 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1540401 0,17939036 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1540401 0,17930357 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1540401 0,17921687 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1540401 0,17913025 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1540401 0,17904371 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1540401 0,17895726 ! ovulation cycle process GO:0022602 49 31 0,000 0,1540401 0,17887089 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1540401 0,1787846 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1540401 0,1786984 ! peptide transport GO:0015833 55 31 0,000 0,1540401 0,17861228 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,1540401 0,17852625 ! mesoderm formation GO:0001707 69 31 0,000 0,1540401 0,17844029 ! natural killer cell activation GO:0030101 45 31 0,000 0,1540401 0,17835442 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1540401 0,17826863 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1540401 0,17818293 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15859523 0,18336382 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15859523 0,18327575 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15859523 0,18318777 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15859523 0,18309986 ! cholesterol transport GO:0030301 56 32 0,000 0,15859523 0,18301205 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15859523 0,18292431 ! spliceosome assembly GO:0000245 67 32 0,000 0,15859523 0,18283666 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15859523 0,1827491 ! metanephros development GO:0001656 74 32 0,000 0,15859523 0,18266162 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15859523 0,18257422 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15859523 0,1824869 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15859523 0,18239967 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15859523 0,18231253 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15859523 0,18222546 ! ovulation cycle GO:0042698 51 32 0,000 0,15859523 0,18213848 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15859523 0,18205158 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15859523 0,18196477 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15859523 0,18187804 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,15859523 0,18179139 ! post-embryonic development GO:0009791 69 33 0,000 0,16312598 0,18689576 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16312598 0,18680681 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16312598 0,18671793 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16312598 0,18662915 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16312598 0,18654045 ! cell fate specification GO:0001708 52 33 0,000 0,16312598 0,18645183 ! sterol transport GO:0015918 57 33 0,000 0,16312598 0,18636329 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16312598 0,18627485 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16312598 0,18618648 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16312598 0,1860982 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16763248 0,19114869 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16763248 0,19105814 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,16763248 0,19096768 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16763248 0,1908773 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16763248 0,19078701 ! mismatch repair GO:0006298 46 34 0,000 0,16763248 0,1906968 ! spermatid development GO:0007286 63 34 0,000 0,16763248 0,19060668 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,16763248 0,19051665 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16763248 0,1904267 ! regulation of muscle development GO:0048634 70 35 0,000 0,17211486 0,19542631 ! negative regulation of secretion GO:0051048 63 35 0,000 0,17211486 0,19533413 ! odontogenesis GO:0042476 66 35 0,000 0,17211486 0,19524203 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,17211486 0,19515003 ! female gonad development GO:0008585 58 35 0,000 0,17211486 0,1950581 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,17211486 0,19496627 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,17211486 0,19487452 ! cytokine production GO:0001816 59 35 0,000 0,17211486 0,19478286 ! neural tube formation GO:0001841 67 35 0,000 0,17211486 0,19469128 ! vesicle localization GO:0051648 64 35 0,000 0,17211486 0,19459979 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,17657325 0,19954685 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17657325 0,19945317 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17657325 0,19935957 ! positive regulation of cell development GO:0010720 80 36 0,000 0,17657325 0,19926607 ! regulation of proteolysis GO:0030162 72 36 0,000 0,17657325 0,19917264 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,17657325 0,19907931 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,17657325 0,19898607 ! embryonic organ development GO:0048568 57 36 0,000 0,17657325 0,19889291 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,17657325 0,19879984 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18100779 0,20369726 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18100779 0,20360203 ! organic anion transport GO:0015711 68 37 0,000 0,18100779 0,20350688 ! tissue remodeling GO:0048771 76 37 0,000 0,18100779 0,20341183 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,18100779 0,20331687 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18100779 0,20322199 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,18100779 0,20312721 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18100779 0,20303251 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,18100779 0,2029379 ! pigment metabolic process GO:0042440 80 37 0,000 0,18100779 0,20284338 ! spermatid differentiation GO:0048515 66 37 0,000 0,18100779 0,20274894 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18541858 0,20759288 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18541858 0,20749633 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18541858 0,20739986 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18541858 0,20730349 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,18541858 0,2072072 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,18541858 0,20711101 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,18541858 0,2070149 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18541858 0,20691888 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18541858 0,20682295 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18541858 0,20672711 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18541858 0,20663136 ! glucan metabolic process GO:0044042 62 38 0,000 0,18541858 0,2065357 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,18980577 0,2113247 ! organic ether metabolic process GO:0018904 55 39 0,000 0,18980577 0,21122696 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,18980577 0,2111293 ! segmentation GO:0035282 67 39 0,000 0,18980577 0,21103174 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18980577 0,21093426 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18980577 0,21083688 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18980577 0,21073958 ! RNA modification GO:0009451 57 39 0,000 0,18980577 0,21064238 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18980577 0,21054526 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,19416947 0,21528652 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19416947 0,21518736 ! feeding behavior GO:0007631 59 40 0,000 0,19416947 0,21508828 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,19416947 0,2149893 ! mesenchymal cell development GO:0014031 87 40 0,000 0,19416947 0,21489041 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,19416947 0,21479161 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19850982 0,21949201 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,19850982 0,21939119 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,19850982 0,21929046 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,19850982 0,21918982 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19850982 0,21908927 ! T cell differentiation GO:0030217 81 41 0,000 0,19850982 0,21898882 ! female gamete generation GO:0007292 61 41 0,000 0,19850982 0,21888846 ! polyol metabolic process GO:0019751 66 41 0,000 0,19850982 0,21878819 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,19850982 0,21868801 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,20282693 0,22334169 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,20282693 0,22323952 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,20282693 0,22313744 ! regulation of tube size GO:0035150 71 42 0,000 0,20282693 0,22303546 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,20282693 0,22293357 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,20282693 0,22283177 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,20282693 0,22273007 ! neuron migration GO:0001764 79 42 0,000 0,20282693 0,22262846 ! regulation of protein secretion GO:0050708 71 42 0,000 0,20282693 0,22252694 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,20712093 0,22713443 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,20712093 0,22703096 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20712093 0,22692757 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,20712093 0,22682428 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,20712093 0,22672109 ! neural tube development GO:0021915 77 43 0,000 0,20712093 0,22661798 ! striated muscle contraction GO:0006941 77 43 0,000 0,20712093 0,22651498 ! phagocytosis GO:0006909 90 43 0,000 0,20712093 0,22641206 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20712093 0,22630924 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,21139194 0,23087109 ! male sex differentiation GO:0046661 76 44 0,000 0,21139194 0,23076634 ! double-strand break repair GO:0006302 81 44 0,000 0,21139194 0,23066168 ! biopolymer methylation GO:0043414 84 44 0,000 0,21139194 0,23055712 ! B cell differentiation GO:0030183 107 44 0,000 0,21139194 0,23045265 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,21139194 0,23034828 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,21139194 0,230244 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,21564008 0,23476473 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,21564008 0,23465855 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,21564008 0,23455246 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,21564008 0,23444647 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,21564008 0,23434058 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,21564008 0,23423478 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21986549 0,23871677 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,21986549 0,23860909 ! response to calcium ion GO:0051592 81 47 0,000 0,22406827 0,24306053 ! endosome transport GO:0016197 108 47 0,000 0,22406827 0,24295099 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,22406827 0,24284155 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,22406827 0,24273222 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22406827 0,24262297 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,22406827 0,24251383 ! JNK cascade GO:0007254 91 47 0,000 0,22406827 0,24240479 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,22406827 0,24229584 ! methylation GO:0032259 90 47 0,000 0,22406827 0,24218699 ! protein homooligomerization GO:0051260 76 47 0,000 0,22406827 0,24207824 ! mitochondrial transport GO:0006839 82 48 0,000 0,22824854 0,24648384 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,22824854 0,24637326 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,22824854 0,24626278 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,22824854 0,2461524 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,22824854 0,24604211 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,23240644 0,25041195 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,23240644 0,25029986 ! regulation of ion transport GO:0043269 77 49 0,000 0,23240644 0,25018787 ! peptide metabolic process GO:0006518 76 49 0,000 0,23240644 0,25007598 ! response to temperature stimulus GO:0009266 76 49 0,000 0,23240644 0,24996419 ! endocrine system development GO:0035270 104 49 0,000 0,23240644 0,2498525 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,23240644 0,24974091 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,23240644 0,24962942 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,23654207 0,25395815 ! neuromuscular process GO:0050905 99 50 0,000 0,23654207 0,25384488 ! inner ear development GO:0048839 79 50 0,000 0,23654207 0,25373171 ! histone modification GO:0016570 91 50 0,000 0,23654207 0,25361864 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,23654207 0,25350567 ! positive regulation of binding GO:0051099 78 51 0,000 0,24065556 0,25779932 ! viral infectious cycle GO:0019058 99 51 0,000 0,24065556 0,25768459 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,24065556 0,25756996 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,24065556 0,25745543 ! excretion GO:0007588 83 51 0,000 0,24065556 0,25734101 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24065556 0,25722669 ! chromatin remodeling GO:0006338 109 51 0,000 0,24065556 0,25711246 ! regulation of cell shape GO:0008360 125 51 0,000 0,24065556 0,25699834 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,24065556 0,25688432 ! positive regulation of growth GO:0045927 90 52 0,000 0,24474701 0,26113584 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,24474701 0,26102009 ! amino acid activation GO:0043038 92 52 0,000 0,24474701 0,26090444 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,24881656 0,26512518 ! RNA catabolic process GO:0006401 93 53 0,000 0,24881656 0,26500781 ! regulation of translational initiation GO:0006446 82 53 0,000 0,24881656 0,26489055 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,24881656 0,2647734 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,24881656 0,26465634 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,24881656 0,2645394 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,25286432 0,26872418 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,25286432 0,26860554 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,25286432 0,268487 ! cell recognition GO:0008037 85 54 0,000 0,25286432 0,26836857 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,25286432 0,26825024 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,25286432 0,26813202 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,25286432 0,2680139 ! chloride transport GO:0006821 90 55 0,000 0,2568904 0,27216129 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,2568904 0,2720415 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,2568904 0,27192182 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,2568904 0,27180224 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,2568904 0,27168277 ! gastrulation GO:0007369 112 55 0,000 0,2568904 0,2715634 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,2568904 0,27144413 ! RNA elongation GO:0006354 79 55 0,000 0,2568904 0,27132498 ! nuclear export GO:0051168 97 55 0,000 0,2568904 0,27120592 ! sensory perception of smell GO:0007608 80 56 0,000 0,26089491 0,27531279 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,26089491 0,27519209 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,26089491 0,2750715 ! proton transport GO:0015992 94 56 0,000 0,26089491 0,27495101 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,26487798 0,27902645 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,26487798 0,27890434 ! hydrogen transport GO:0006818 97 58 0,000 0,26883972 0,28295204 ! adult behavior GO:0030534 99 58 0,000 0,26883972 0,28282832 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,26883972 0,2827047 ! positive regulation of secretion GO:0051047 95 59 0,000 0,27278023 0,28672313 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,27278023 0,28659792 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,27669964 0,29058897 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,27669964 0,29046219 ! camera-type eye development GO:0043010 116 60 0,000 0,27669964 0,29033552 ! kidney development GO:0001822 122 60 0,000 0,27669964 0,29020895 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,28059806 0,29416947 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,28059806 0,29404134 ! tRNA processing GO:0008033 89 61 0,000 0,28059806 0,29391333 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,28059806 0,29378543 ! viral reproductive process GO:0022415 126 62 0,000 0,28447559 0,29771564 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,28447559 0,2975862 ! gonad development GO:0008406 98 62 0,000 0,28447559 0,29745687 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,28833235 0,30135866 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,29216845 0,30523547 ! cell redox homeostasis GO:0045454 102 64 0,000 0,29216845 0,30510299 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29216845 0,30497063 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,295984 0,30881939 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,295984 0,30868552 ! germ cell development GO:0007281 118 65 0,000 0,295984 0,30855178 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,29977911 0,31237269 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,29977911 0,31223746 ! extracellular matrix organization GO:0030198 133 66 0,000 0,29977911 0,31210235 ! secondary metabolic process GO:0019748 116 66 0,000 0,29977911 0,31196736 ! cell projection assembly GO:0030031 120 66 0,000 0,29977911 0,31183248 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,30355388 0,31562258 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,30355388 0,31548624 ! activation of MAPK activity GO:0000187 115 67 0,000 0,30355388 0,31535002 ! lung development GO:0030324 144 67 0,000 0,30355388 0,31521392 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,30355388 0,31507793 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,30355388 0,31494206 ! adaptive immune response GO:0002250 119 67 0,000 0,30355388 0,31480631 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,30355388 0,31467068 ! amino acid transport GO:0006865 125 68 0,000 0,30730844 0,31842554 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,30730844 0,31828846 ! viral reproduction GO:0016032 134 68 0,000 0,30730844 0,3181515 ! regulation of lipase activity GO:0060191 130 68 0,000 0,30730844 0,31801466 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,31104287 0,32174082 ! urogenital system development GO:0001655 137 69 0,000 0,31104287 0,32160256 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,31104287 0,32146441 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,31104287 0,32132638 ! antigen processing and presentation GO:0019882 104 69 0,000 0,31104287 0,32118847 ! respiratory tube development GO:0030323 150 70 0,000 0,3147573 0,32488462 ! reproductive structure development GO:0048608 113 71 0,000 0,31845182 0,32855706 ! humoral immune response GO:0006959 109 71 0,000 0,31845182 0,32841623 ! B cell activation GO:0042113 160 71 0,000 0,31845182 0,32827552 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,31845182 0,32813494 ! regulation of immune effector process GO:0002697 137 71 0,000 0,31845182 0,32799447 ! acute inflammatory response GO:0002526 113 72 0,000 0,32212654 0,33163734 ! respiratory system development GO:0060541 153 72 0,000 0,32212654 0,33149549 ! regulation of blood pressure GO:0008217 125 73 0,000 0,32578158 0,3351135 ! transition metal ion transport GO:0000041 126 74 0,000 0,32941703 0,33870827 ! neurotransmitter transport GO:0006836 123 74 0,000 0,32941703 0,33856359 ! exocytosis GO:0006887 133 74 0,000 0,32941703 0,33841903 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,32941703 0,33827459 ! eye development GO:0001654 143 74 0,000 0,32941703 0,33813027 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,33303299 0,34169611 ! rhythmic process GO:0048511 128 75 0,000 0,33303299 0,34155046 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,33303299 0,34140493 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,33662958 0,34494496 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,33662958 0,34479811 ! defense response to bacterium GO:0042742 89 76 0,000 0,33662958 0,34465139 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,33662958 0,34450479 ! regulation of catabolic process GO:0009894 161 76 0,000 0,33662958 0,34435832 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,34020689 0,34786986 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,34376503 0,35135882 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,34376503 0,35120962 ! protein oligomerization GO:0051259 139 78 0,000 0,34376503 0,35106055 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3473041 0,35452425 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,3473041 0,3543739 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,35082419 0,35781391 ! response to metal ion GO:0010038 140 80 0,000 0,35082419 0,35766229 ! inorganic anion transport GO:0015698 138 80 0,000 0,35082419 0,35751081 ! T cell activation GO:0042110 168 81 0,000 0,35432543 0,3609259 ! digestion GO:0007586 112 81 0,000 0,35432543 0,36077316 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,35432543 0,36062055 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,35780789 0,3640109 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,35780789 0,36385705 ! response to drug GO:0042493 143 82 0,000 0,35780789 0,36370333 ! response to nutrient GO:0007584 125 82 0,000 0,35780789 0,36354974 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,35780789 0,36339628 ! regulation of lyase activity GO:0051339 160 83 0,000 0,36127169 0,36675936 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,36471691 0,37010076 ! response to unfolded protein GO:0006986 131 85 0,000 0,36814367 0,37342061 ! nucleosome assembly GO:0006334 122 85 0,000 0,36814367 0,37326324 ! response to inorganic substance GO:0010035 153 86 0,000 0,37155206 0,37656035 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,37155206 0,37640179 ! chromatin assembly GO:0031497 124 86 0,000 0,37155206 0,37624338 ! tube morphogenesis GO:0035239 176 86 0,000 0,37155206 0,37608509 ! amine transport GO:0015837 155 86 0,000 0,37155206 0,37592694 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,37494218 0,37919751 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ATP biosynthetic process GO:0006754 159 88 0,000 0,37831412 0,38244696 ! cellular defense response GO:0006968 114 89 0,000 0,38166798 0,38567541 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,38166798 0,3855135 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,38500386 0,3887198 ! sex differentiation GO:0007548 145 90 0,000 0,38500386 0,38855675 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,38500386 0,38839383 ! sterol metabolic process GO:0016125 152 91 0,000 0,38832185 0,39157685 ! response to protein stimulus GO:0051789 149 91 0,000 0,38832185 0,39141281 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,38832185 0,3912489 ! nucleosome organization GO:0034728 138 92 0,000 0,39162205 0,39440882 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,39162205 0,39424379 ! vitamin metabolic process GO:0006766 139 92 0,000 0,39162205 0,3940789 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,39490456 0,39721587 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,39490456 0,39704988 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,39490456 0,39688403 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,39816946 0,39999822 ! leukocyte differentiation GO:0002521 202 96 0,000 0,40464684 0,40633568 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,40464684 0,40616616 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,40464684 0,40599679 ! positive regulation of immune response GO:0050778 156 96 0,000 0,40464684 0,40582755 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,4078595 0,40887915 ! protein ubiquitination GO:0016567 217 97 0,000 0,4078595 0,40870885 ! hormone metabolic process GO:0042445 157 97 0,000 0,4078595 0,4085387 ! response to virus GO:0009615 160 98 0,000 0,41105492 0,4115681 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,41105492 0,4113969 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,41423322 0,41440545 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,41423322 0,41423322