pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6849-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 10,000 6,374E-12 1,557E-08 ! induction of apoptosis by extracellular signals GO:0008624 99 50 8,000 6,711E-12 8,198E-09 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 6,000 5,323E-11 4,335E-08 ! S phase GO:0051320 10 9 4,000 5,404E-10 3,301E-07 GO:0000084|S phase of mitotic cell cycle, ! mitotic sister chromatid segregation GO:0000070 63 36 5,000 3,91E-08 1,91E-05 ! sister chromatid segregation GO:0000819 65 37 5,000 4,646E-08 1,892E-05 ! chromosome segregation GO:0007059 127 67 6,000 7,953E-08 2,775E-05 ! negative regulation of protein kinase activity GO:0006469 144 69 6,000 9,777E-08 2,986E-05 ! negative regulation of kinase activity GO:0033673 145 70 6,000 1,081E-07 2,935E-05 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 1,57E-07 3,836E-05 ! negative regulation of transferase activity GO:0051348 155 74 6,000 1,594E-07 3,54E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 3,000 1,689E-07 3,439E-05 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 1,707E-07 3,208E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 1,798E-07 3,137E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 2,619E-07 4,265E-05 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of B cell proliferation GO:0030888 22 12 3,000 3,949E-07 6,029E-05 ! negative regulation of mast cell proliferation GO:0070667 24 12 3,000 3,949E-07 5,674E-05 GO:0042130|negative regulation of T cell proliferation, ! regulation of DNA metabolic process GO:0051052 188 97 6,000 1,025E-06 1,391E-04 ! negative regulation of leukocyte proliferation GO:0070664 32 16 3,000 1,427E-06 1,835E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 3,000 1,859E-06 2,27E-04 ! L-serine biosynthetic process GO:0006564 7 6 2,000 3,067E-06 3,567E-04 ! negative regulation of B cell activation GO:0050869 14 6 2,000 3,067E-06 3,405E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 3,736E-06 3,968E-04 ! negative regulation of T cell activation GO:0050868 41 20 3,000 3,736E-06 3,803E-04 ! cell structure disassembly during apoptosis GO:0006921 32 21 3,000 4,596E-06 4,491E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 5,345E-06 5,022E-04 ! apoptotic nuclear changes GO:0030262 34 22 3,000 5,593E-06 5,061E-04 ! regulation of mast cell proliferation GO:0070666 89 49 4,000 6,863E-06 5,988E-04 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 3,000 8,057E-06 6,787E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 8,518E-06 6,937E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 8,518E-06 6,713E-04 ! regulation of leukocyte proliferation GO:0070663 97 53 4,000 1,015E-05 7,749E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,273E-05 9,421E-04 ! negative regulation of lymphocyte activation GO:0051250 55 27 3,000 1,314E-05 9,44E-04 ! regulation of DNA replication GO:0006275 105 56 4,000 1,333E-05 9,307E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,455E-05 9,875E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,811E-05 1,196E-03 ! regulation of DNA replication initiation GO:0030174 14 10 2,000 1,811E-05 1,164E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 2,000 1,811E-05 1,134E-03 ! regulation of B cell activation GO:0050864 55 30 3,000 2,026E-05 1,237E-03 ! cell junction assembly GO:0034329 85 31 3,000 2,316E-05 1,38E-03 ! negative regulation of leukocyte activation GO:0002695 60 31 3,000 2,316E-05 1,347E-03 ! L-serine metabolic process GO:0006563 21 11 2,000 2,48E-05 1,409E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,48E-05 1,377E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,48E-05 1,346E-03 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 22 12 2,000 3,293E-05 1,749E-03 GO:0050927|positive regulation of positive chemotaxis, ! cell cycle checkpoint GO:0000075 145 71 4,000 4,257E-05 2,213E-03 ! cell junction organization GO:0034330 96 37 3,000 4,74E-05 2,412E-03 ! negative regulation of cell activation GO:0050866 69 37 3,000 4,74E-05 2,363E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 5,198E-05 2,54E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 5,406E-05 2,589E-03 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 5,406E-05 2,54E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 5,406E-05 2,492E-03 ! nucleus organization GO:0006997 73 40 3,000 6,476E-05 2,93E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 6,73E-05 2,99E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 8,019E-05 3,498E-03 ! regulation of T cell proliferation GO:0042129 80 43 3,000 8,636E-05 3,701E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 9,008E-05 3,794E-03 GO:0045937|positive regulation of phosphate metabolic process, ! induction of apoptosis via death domain receptors GO:0008625 23 17 2,000 9,979E-05 4,132E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 9,979E-05 4,063E-03 ! glycolysis GO:0006096 71 46 3,000 1,128E-04 4,516E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 1,193E-04 4,7E-03 ! regulation of BMP signaling pathway GO:0030510 33 18 2,000 1,193E-04 4,625E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 2,000 1,193E-04 4,553E-03 ! positive regulation of protein modification process GO:0031401 156 90 4,000 1,323E-04 4,971E-03 ! cellular component disassembly GO:0022411 89 48 3,000 1,333E-04 4,935E-03 ! actin filament bundle formation GO:0051017 47 20 2,000 1,653E-04 6,027E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,653E-04 5,939E-03 GO:0010827|regulation of glucose transport, ! negative regulation of immune system process GO:0002683 101 51 3,000 1,691E-04 5,986E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,921E-04 6,704E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 2,215E-04 7,623E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 2,215E-04 7,517E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 2,000 2,215E-04 7,414E-03 ! glucose catabolic process GO:0006007 88 56 3,000 2,433E-04 8,033E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 2,538E-04 8,266E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,538E-04 8,157E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 2,872E-04 9,112E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 2,872E-04 8,995E-03 ! Notch receptor processing GO:0007220 11 5 1,000 2,872E-04 8,881E-03 ! glial cell fate commitment GO:0021781 14 5 1,000 2,872E-04 8,77E-03 ! skeletal myofibril assembly GO:0014866 12 5 1,000 2,872E-04 8,662E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,872E-04 8,556E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,872E-04 8,453E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,872E-04 8,352E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! peptidyl-histidine phosphorylation GO:0018106 10 5 1,000 2,872E-04 8,254E-03 ! G2/M transition checkpoint GO:0031576 8 5 1,000 2,872E-04 8,158E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,872E-04 8,064E-03 ! cardiac myofibril assembly GO:0055003 11 5 1,000 2,872E-04 7,973E-03 ! decidualization GO:0046697 11 5 1,000 2,872E-04 7,883E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,872E-04 7,796E-03 ! protein palmitoylation GO:0018345 12 5 1,000 2,872E-04 7,71E-03 ! stem cell division GO:0017145 11 5 1,000 2,872E-04 7,626E-03 GO:0048103|somatic stem cell division, ! pallium development GO:0021543 56 24 2,000 2,889E-04 7,588E-03 ! DNA catabolic process GO:0006308 94 60 3,000 3,177E-04 8,256E-03 ! regulation of behavior GO:0050795 48 25 2,000 3,269E-04 8,408E-03 ! myelination GO:0042552 50 26 2,000 3,681E-04 9,368E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 3,681E-04 9,271E-03 ! blastocyst development GO:0001824 50 26 2,000 3,681E-04 9,177E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 4,125E-04 0,01017898 ! regulation of chromosome organization GO:0033044 49 27 2,000 4,125E-04 0,01007719 ! erythrocyte maturation GO:0043249 8 6 1,000 4,292E-04 0,01038268 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 4,292E-04 0,01028089 ! neuron apoptosis GO:0051402 15 6 1,000 4,292E-04 0,01018107 ! establishment of spindle localization GO:0051293 16 6 1,000 4,292E-04 0,01008318 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 4,292E-04 9,987E-03 GO:0045686|negative regulation of glial cell differentiation, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 4,292E-04 9,893E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,292E-04 9,8E-03 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 4,292E-04 9,71E-03 ! maternal placenta development GO:0001893 12 6 1,000 4,292E-04 9,621E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 4,602E-04 0,01021974 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 4,602E-04 0,01012767 ! negative regulation of cell growth GO:0030308 142 67 3,000 4,848E-04 0,01057548 ! hexose catabolic process GO:0019320 113 68 3,000 5,13E-04 0,01109036 ! negative regulation of cell size GO:0045792 144 69 3,000 5,423E-04 0,01162069 ! homeostasis of number of cells GO:0048872 131 69 3,000 5,423E-04 0,01151964 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 5,423E-04 0,01142033 ! developmental maturation GO:0021700 128 69 3,000 5,423E-04 0,01132272 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,988E-04 0,01239735 ! lipoprotein transport GO:0042953 14 7 1,000 5,988E-04 0,01229317 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 5,988E-04 0,01219073 ! induction of apoptosis by oxidative stress GO:0008631 9 7 1,000 5,988E-04 0,01208998 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 5,988E-04 0,01199088 ! peptidyl-histidine modification GO:0018202 17 7 1,000 5,988E-04 0,0118934 ! erythrocyte differentiation GO:0030218 62 31 2,000 6,239E-04 0,01229202 ! ensheathment of neurons GO:0007272 64 31 2,000 6,239E-04 0,01219369 GO:0008366|axon ensheathment, ! actin filament organization GO:0007015 167 72 3,000 6,372E-04 0,0123555 ! spindle organization GO:0007051 50 32 2,000 6,857E-04 0,01319076 ! leukocyte chemotaxis GO:0030595 55 33 2,000 7,513E-04 0,01433947 GO:0060326|cell chemotaxis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 7,956E-04 0,01506651 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,956E-04 0,01495062 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 7,956E-04 0,01483649 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,956E-04 0,01472409 ! hemoglobin metabolic process GO:0020027 14 8 1,000 7,956E-04 0,01461339 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,956E-04 0,01450433 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 7,956E-04 0,01439689 ! cardiac muscle cell development GO:0055013 14 8 1,000 7,956E-04 0,01429103 ! blastocyst growth GO:0001832 19 8 1,000 7,956E-04 0,01418672 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 7,956E-04 0,01408391 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 7,956E-04 0,01398259 GO:0000076|DNA replication checkpoint, ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 8,208E-04 0,0143222 ! serine family amino acid metabolic process GO:0009069 56 34 2,000 8,208E-04 0,01422062 ! monosaccharide catabolic process GO:0046365 125 77 3,000 8,208E-04 0,01412201 ! telencephalon development GO:0021537 81 35 2,000 8,941E-04 0,01527558 ! cell proliferation in forebrain GO:0021846 18 9 1,000 1,019E-03 0,01729171 ! regulation of activated T cell proliferation GO:0046006 19 9 1,000 1,019E-03 0,01717246 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,019E-03 0,01705484 ! DNA synthesis during DNA repair GO:0000731 18 9 1,000 1,019E-03 0,01693882 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 1,000 1,019E-03 0,01682436 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 1,019E-03 0,01671145 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,019E-03 0,01660004 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,019E-03 0,01649011 ! erythrocyte development GO:0048821 17 9 1,000 1,019E-03 0,01638162 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,019E-03 0,01627455 ! branched chain family amino acid catabolic process GO:0009083 19 9 1,000 1,019E-03 0,01616887 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,019E-03 0,01606455 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 1,000 1,019E-03 0,01596158 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 2,000 1,139E-03 0,01772136 ! DNA integrity checkpoint GO:0031570 82 38 2,000 1,139E-03 0,0176092 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,139E-03 0,01749845 ! negative regulation of transport GO:0051051 164 85 3,000 1,188E-03 0,01813447 ! negative regulation of growth GO:0045926 168 85 3,000 1,188E-03 0,01802184 ! erythrocyte homeostasis GO:0034101 75 39 2,000 1,229E-03 0,01853204 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,27E-03 0,01902729 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,27E-03 0,01891127 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 1,27E-03 0,01879666 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,27E-03 0,01868342 ! pathogenesis GO:0009405 17 10 1,000 1,27E-03 0,01857155 ! motor axon guidance GO:0008045 22 10 1,000 1,27E-03 0,018461 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,27E-03 0,01835176 GO:0045685|regulation of glial cell differentiation, ! synaptic vesicle endocytosis GO:0048488 23 10 1,000 1,27E-03 0,01824381 ! blastocyst formation GO:0001825 18 10 1,000 1,27E-03 0,01813712 ! mitochondrion organization GO:0007005 159 87 3,000 1,295E-03 0,01839023 ! alcohol catabolic process GO:0046164 142 87 3,000 1,295E-03 0,01828393 ! regulation of action potential in neuron GO:0019228 80 40 2,000 1,323E-03 0,01857921 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,525E-03 0,02129535 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,546E-03 0,02146134 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,546E-03 0,02134009 GO:0010812|negative regulation of cell-substrate adhesion, ! neuroblast proliferation GO:0007405 25 11 1,000 1,546E-03 0,0212202 ! nucleus localization GO:0051647 22 11 1,000 1,546E-03 0,02110165 ! striated muscle cell differentiation GO:0051146 91 43 2,000 1,633E-03 0,0221687 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 1,746E-03 0,02356594 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 1,746E-03 0,02343645 ! hippocampus development GO:0021766 29 12 1,000 1,849E-03 0,02468056 ! focal adhesion formation GO:0048041 37 12 1,000 1,849E-03 0,02454643 ! T cell homeostasis GO:0043029 28 12 1,000 1,849E-03 0,02441375 ! embryonic placenta development GO:0001892 21 12 1,000 1,849E-03 0,02428249 ! regulation of T cell activation GO:0050863 175 96 3,000 1,861E-03 0,02431204 ! keratinocyte differentiation GO:0030216 81 45 2,000 1,863E-03 0,02421313 ! leukocyte migration GO:0050900 75 46 2,000 1,985E-03 0,02566368 ! pigmentation GO:0043473 103 46 2,000 1,985E-03 0,02552861 ! forebrain development GO:0030900 210 98 3,000 2,007E-03 0,02566778 ! response to insulin stimulus GO:0032868 98 47 2,000 2,112E-03 0,02687867 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 2,177E-03 0,0275585 ! Golgi organization GO:0007030 25 13 1,000 2,177E-03 0,02741645 ! membrane protein proteolysis GO:0033619 33 13 1,000 2,177E-03 0,02727585 GO:0006509|membrane protein ectodomain proteolysis, ! chromatin silencing GO:0006342 29 13 1,000 2,177E-03 0,02713669 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,177E-03 0,02699894 ! positive regulation of cell cycle GO:0045787 96 48 2,000 2,244E-03 0,02769212 ! positive regulation of defense response GO:0031349 88 48 2,000 2,244E-03 0,02755296 ! regulation of inflammatory response GO:0050727 84 48 2,000 2,244E-03 0,0274152 ! response to calcium ion GO:0051592 94 49 2,000 2,381E-03 0,02894327 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 2,381E-03 0,02879998 ! regulation of action potential GO:0001508 102 50 2,000 2,523E-03 0,03036716 ! activation of caspase activity GO:0006919 95 50 2,000 2,523E-03 0,0302183 ! epidermal cell differentiation GO:0009913 87 50 2,000 2,523E-03 0,0300709 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 2,531E-03 0,03001576 GO:0046579|positive regulation of Ras protein signal transduction, ! cell-cell junction assembly GO:0007043 32 14 1,000 2,531E-03 0,02987075 ! embryo implantation GO:0007566 30 14 1,000 2,531E-03 0,02972714 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 2,531E-03 0,02958491 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 2,823E-03 0,03283881 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,91E-03 0,03369298 ! glycoprotein catabolic process GO:0006516 33 15 1,000 2,91E-03 0,03353405 ! cartilage development GO:0051216 99 53 2,000 2,98E-03 0,03418367 ! regulation of muscle contraction GO:0006937 94 54 2,000 3,143E-03 0,03588347 ! cell maturation GO:0048469 107 55 2,000 3,312E-03 0,0376284 ! response to UV GO:0009411 120 55 2,000 3,312E-03 0,03745419 ! negative regulation of cell motion GO:0051271 142 55 2,000 3,312E-03 0,03728159 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 3,314E-03 0,03713774 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 3,314E-03 0,03696816 ! heterophilic cell adhesion GO:0007157 43 16 1,000 3,314E-03 0,03680012 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 3,314E-03 0,03663361 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 3,314E-03 0,03646859 ! DNA replication initiation GO:0006270 28 16 1,000 3,314E-03 0,03630505 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,664E-03 0,03996448 GO:0010952|positive regulation of peptidase activity, ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,743E-03 0,04063553 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 1,000 3,743E-03 0,04045572 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,743E-03 0,0402775 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 3,743E-03 0,04010085 ! limbic system development GO:0021761 40 18 1,000 4,195E-03 0,0447574 ! epidermis morphogenesis GO:0048730 43 18 1,000 4,195E-03 0,04456281 ! lipid modification GO:0030258 112 60 2,000 4,235E-03 0,04479003 ! cytokine-mediated signaling pathway GO:0019221 112 61 2,000 4,437E-03 0,04671933 ! regulation of heart contraction GO:0008016 123 61 2,000 4,437E-03 0,04651882 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 4,437E-03 0,04632002 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 4,672E-03 0,04857327 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 4,672E-03 0,04836745 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,672E-03 0,04816337 ! memory GO:0007613 34 19 1,000 4,672E-03 0,047961 ! cerebral cortex development GO:0021987 40 19 1,000 4,672E-03 0,04776033 ! pigmentation during development GO:0048066 42 19 1,000 4,672E-03 0,04756132 ! neuromuscular junction development GO:0007528 43 19 1,000 4,672E-03 0,04736397 ! heart process GO:0003015 32 19 1,000 4,672E-03 0,04716826 GO:0060047|heart contraction, ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 5,076E-03 0,05103032 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 5,076E-03 0,05082118 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,173E-03 0,05158428 ! response to alkaloid GO:0043279 38 20 1,000 5,173E-03 0,05137459 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 5,173E-03 0,05116659 ! fatty acid beta-oxidation GO:0006635 36 20 1,000 5,173E-03 0,05096028 ! cell-cell junction organization GO:0045216 43 20 1,000 5,173E-03 0,05075562 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 5,173E-03 0,0505526 ! negative regulation of translation GO:0017148 32 20 1,000 5,173E-03 0,05035119 ! lipid phosphorylation GO:0046834 43 21 1,000 5,698E-03 0,05523446 ! plasma membrane fusion GO:0045026 33 21 1,000 5,698E-03 0,05501614 ! prostaglandin metabolic process GO:0006693 43 21 1,000 5,698E-03 0,05479954 GO:0006692|prostanoid metabolic process, ! negative regulation of intracellular transport GO:0032387 44 21 1,000 5,698E-03 0,05458464 ! actin filament-based movement GO:0030048 47 21 1,000 5,698E-03 0,05437142 ! myeloid cell differentiation GO:0030099 126 67 2,000 5,768E-03 0,05482723 ! hindlimb morphogenesis GO:0035137 47 22 1,000 6,245E-03 0,05913516 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 6,245E-03 0,05890683 ! peptidyl-serine modification GO:0018209 50 22 1,000 6,245E-03 0,05868027 ! positive regulation of B cell activation GO:0050871 42 22 1,000 6,245E-03 0,05845544 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,245E-03 0,05823233 ! positive regulation of DNA replication GO:0045740 44 23 1,000 6,816E-03 0,06331127 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 6,816E-03 0,06307146 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 6,816E-03 0,06283345 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 1,000 6,816E-03 0,06259724 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 1,000 6,816E-03 0,06236279 GO:0060415|muscle tissue morphogenesis, ! acetyl-CoA catabolic process GO:0046356 37 23 1,000 6,816E-03 0,06213009 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 7,409E-03 0,06728784 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,409E-03 0,06703862 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 7,409E-03 0,06679125 ! synaptic vesicle transport GO:0048489 52 24 1,000 7,409E-03 0,06654569 ! platelet activation GO:0030168 41 24 1,000 7,409E-03 0,06630193 ! regulation of caspase activity GO:0043281 136 74 2,000 7,593E-03 0,06770042 ! organelle localization GO:0051640 155 74 2,000 7,593E-03 0,06745424 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 8,025E-03 0,07103234 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 8,025E-03 0,0707759 ! regulation of transmembrane transport GO:0034762 39 25 1,000 8,025E-03 0,07052131 ! leukocyte adhesion GO:0007159 55 25 1,000 8,025E-03 0,07026855 ! vasculogenesis GO:0001570 49 25 1,000 8,025E-03 0,07001759 ! negative regulation of DNA replication GO:0008156 45 25 1,000 8,025E-03 0,06976842 ! leukocyte homeostasis GO:0001776 50 25 1,000 8,025E-03 0,06952101 ! learning or memory GO:0007611 161 76 2,000 8,17E-03 0,07052888 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 8,468E-03 0,07284349 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 8,663E-03 0,07425869 ! microtubule organizing center organization GO:0031023 42 26 1,000 8,663E-03 0,07399904 GO:0051297|centrosome organization, ! coenzyme catabolic process GO:0009109 42 26 1,000 8,663E-03 0,0737412 ! negative regulation of cell development GO:0010721 83 26 1,000 8,663E-03 0,07348516 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 8,663E-03 0,07323088 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 8,663E-03 0,07297836 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 9,083E-03 0,07625313 ! acetyl-CoA metabolic process GO:0006084 41 27 1,000 9,323E-03 0,07800071 ! muscle cell differentiation GO:0042692 178 81 2,000 9,723E-03 0,0810717 ! response to hypoxia GO:0001666 178 81 2,000 9,723E-03 0,08079594 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01000481 0,08285338 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01000481 0,08257347 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01000481 0,08229544 ! lipid oxidation GO:0034440 48 28 1,000 0,01000481 0,08201929 GO:0019395|fatty acid oxidation, ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01005308 0,08213938 ! protein import into nucleus GO:0006606 174 82 2,000 0,01005308 0,08186558 ! response to oxygen levels GO:0070482 183 83 2,000 0,01038931 0,08432254 ! nuclear import GO:0051170 177 83 2,000 0,01038931 0,08404332 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01070804 0,08633576 ! respiratory gaseous exchange GO:0007585 61 29 1,000 0,01070804 0,08605176 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 0,01070804 0,08576962 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01070804 0,08548933 ! response to metal ion GO:0010038 158 84 2,000 0,010732 0,08540159 ! regulation of ligase activity GO:0051340 147 84 2,000 0,010732 0,08512431 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 0,01108119 0,08760952 ! myofibril assembly GO:0030239 50 30 1,000 0,01143248 0,09009535 GO:0055002|striated muscle cell development, ! cell fate determination GO:0001709 64 30 1,000 0,01143248 0,08980566 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01143248 0,08951782 GO:0043433|negative regulation of transcription factor activity, ! amine biosynthetic process GO:0009309 146 88 2,000 0,01216786 0,09497151 ! iron ion homeostasis GO:0055072 60 31 1,000 0,0121779 0,09474719 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,0121779 0,09444641 ! cofactor catabolic process GO:0051187 54 31 1,000 0,0121779 0,09414753 ! fatty acid catabolic process GO:0009062 54 31 1,000 0,0121779 0,09385053 ! protein localization in nucleus GO:0034504 192 89 2,000 0,01254319 0,09636168 ! response to inorganic substance GO:0010035 173 90 2,000 0,0129251 0,09898439 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,0129251 0,09867507 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01294405 0,09851187 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01294405 0,09820594 ! muscle cell development GO:0055001 52 32 1,000 0,01294405 0,09790189 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01294405 0,09759973 ! hindbrain development GO:0030902 65 32 1,000 0,01294405 0,09729942 ! gene silencing GO:0016458 71 32 1,000 0,01294405 0,09700096 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01370873 0,10241721 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01373068 0,10226843 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01373068 0,10195758 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01373068 0,10164862 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01411048 0,10414471 ! female pregnancy GO:0007565 166 94 2,000 0,01451887 0,10683613 ! regulation of membrane potential GO:0042391 179 94 2,000 0,01451887 0,1065153 ! glial cell differentiation GO:0010001 67 34 1,000 0,01453755 0,10633302 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01453755 0,10601561 ! regulation of defense response GO:0031347 171 95 2,000 0,01493391 0,10858197 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01536442 0,11138065 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01536442 0,11105112 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01536442 0,11072353 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01536442 0,11039787 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01536442 0,11007413 ! placenta development GO:0001890 53 35 1,000 0,01536442 0,10975227 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,01621106 0,11546243 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01621106 0,11512678 ! aerobic respiration GO:0009060 56 36 1,000 0,01621106 0,11479308 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01707723 0,12057706 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01707723 0,12022957 ! actomyosin structure organization GO:0031032 68 37 1,000 0,01707723 0,11988409 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01707723 0,11954058 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,01707723 0,11919903 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01707723 0,11885943 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01796269 0,12466719 ! meiosis I GO:0007127 74 38 1,000 0,01796269 0,12431403 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,01796269 0,12396286 ! regulation of protein stability GO:0031647 77 38 1,000 0,01796269 0,12361366 ! negative regulation of binding GO:0051100 71 39 1,000 0,01886722 0,12947364 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01886722 0,12911097 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01886722 0,12875033 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,01979058 0,1346752 ! learning GO:0007612 82 40 1,000 0,01979058 0,1343011 ! gliogenesis GO:0042063 91 41 1,000 0,02073256 0,1403037 ! maintenance of protein location GO:0045185 95 41 1,000 0,02073256 0,13991612 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,02169291 0,1459939 ! ear morphogenesis GO:0042471 64 42 1,000 0,02169291 0,14559281 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,02169291 0,14519393 ! cytokinesis GO:0000910 84 42 1,000 0,02169291 0,14479723 ! glucose transport GO:0015758 66 43 1,000 0,02267143 0,15091633 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,02267143 0,15050623 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02267143 0,15009835 ! hexose transport GO:0008645 68 44 1,000 0,02366788 0,15627194 GO:0015749|monosaccharide transport, ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02468204 0,16252891 ! developmental growth GO:0048589 88 45 1,000 0,02468204 0,16209201 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02468204 0,16165744 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,0257137 0,16796412 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,0257137 0,16751621 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,0257137 0,16707069 ! cell growth GO:0016049 90 46 1,000 0,0257137 0,16662753 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02672005 0,17269068 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02672005 0,17223503 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02672005 0,17178178 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02672005 0,17133091 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02672005 0,1708824 ! neuron fate determination GO:0048664 7 5 0,000 0,02672005 0,17043623 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02672005 0,16999239 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02672005 0,16955085 ! polyol transport GO:0015791 12 5 0,000 0,02672005 0,1691116 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02672005 0,16867461 ! response to superoxide GO:0000303 10 5 0,000 0,02672005 0,16823989 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02672005 0,16780739 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02672005 0,16737712 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02672005 0,16694904 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02672005 0,16652315 ! female meiosis GO:0007143 10 5 0,000 0,02672005 0,16609943 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02672005 0,16567786 ! hypothalamus development GO:0021854 9 5 0,000 0,02672005 0,16525842 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02672005 0,1648411 ! cobalt ion transport GO:0006824 11 5 0,000 0,02672005 0,16442588 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02672005 0,16401275 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02672005 0,16360169 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02672005 0,16319269 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02672005 0,16278573 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02672005 0,16238079 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02672005 0,16197786 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02672005 0,16157692 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02672005 0,16117797 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02672005 0,16078098 ! transposition GO:0032196 9 5 0,000 0,02672005 0,16038594 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02672005 0,15999283 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02672005 0,15960165 ! negative chemotaxis GO:0050919 16 5 0,000 0,02672005 0,15921238 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02672005 0,158825 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02672005 0,1584395 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02672005 0,15805587 ! behavioral response to pain GO:0048266 10 5 0,000 0,02672005 0,1576741 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02672005 0,15729416 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02672005 0,15691605 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02672005 0,15653975 ! micturition GO:0060073 9 5 0,000 0,02672005 0,15616525 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02672005 0,15579254 ! copulation GO:0007620 9 5 0,000 0,02672005 0,15542161 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02672005 0,15505244 ! bioluminescence GO:0008218 9 5 0,000 0,02672005 0,15468501 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02672005 0,15431933 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02672005 0,15395537 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02672005 0,15359312 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02672005 0,15323257 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02672005 0,15287371 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02672005 0,15251653 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02672005 0,15216102 ! grooming behavior GO:0007625 6 5 0,000 0,02672005 0,15180715 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02672005 0,15145493 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02672005 0,15110434 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02672005 0,15075537 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02672005 0,15040801 ! response to protozoan GO:0001562 13 5 0,000 0,02672005 0,15006224 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02672005 0,14971806 ! lymph vessel development GO:0001945 10 5 0,000 0,02672005 0,14937546 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02672005 0,14903442 ! endochondral ossification GO:0001958 17 5 0,000 0,02672005 0,14869493 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02672005 0,14835699 ! single strand break repair GO:0000012 8 5 0,000 0,02672005 0,14802058 ! parathyroid gland development GO:0060017 14 5 0,000 0,02672005 0,14768569 ! anagen GO:0042640 7 5 0,000 0,02672005 0,14735232 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02672005 0,14702044 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02672005 0,14669006 ! cytokine secretion GO:0050663 15 5 0,000 0,02672005 0,14636116 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02672005 0,14603373 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02672005 0,14570776 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02672005 0,14538324 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02672005 0,14506017 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02672005 0,14473853 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02672005 0,14441831 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02672005 0,14409951 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02672005 0,14378211 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02672005 0,1434661 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02672005 0,14315148 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02672005 0,14283824 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02672005 0,14252637 ! microvillus organization GO:0032528 8 5 0,000 0,02672005 0,14221585 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02672005 0,14190669 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02672005 0,14159886 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02672005 0,14129237 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02672005 0,1409872 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02672005 0,14068335 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02672005 0,14038081 ! polyol catabolic process GO:0046174 9 5 0,000 0,02672005 0,14007956 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02672005 0,13977961 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02672005 0,13948093 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02672005 0,13918353 ! muscle cell migration GO:0014812 8 5 0,000 0,02672005 0,1388874 ! mitochondrial fission GO:0000266 8 5 0,000 0,02672005 0,13859252 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02672005 0,13829889 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02672005 0,1380065 ! mRNA transcription GO:0009299 10 5 0,000 0,02672005 0,13771535 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02672005 0,13742542 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02672005 0,13713671 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02672005 0,13684922 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02672005 0,13656292 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02672005 0,13627782 ! monocyte activation GO:0042117 10 5 0,000 0,02672005 0,13599391 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02672005 0,13571118 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02672005 0,13542962 ! response to food GO:0032094 6 5 0,000 0,02672005 0,13514923 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02672005 0,13486999 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02672005 0,13459191 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02672005 0,13431497 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02672005 0,13403917 ! forebrain neuron development GO:0021884 13 5 0,000 0,02672005 0,1337645 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02672005 0,13349095 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02672005 0,13321852 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02672005 0,1329472 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02672005 0,13267698 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02672005 0,13240786 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02672005 0,13213983 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02672005 0,13187288 ! lipid glycosylation GO:0030259 7 5 0,000 0,02672005 0,13160701 ! nucleobase transport GO:0015851 6 5 0,000 0,02672005 0,1313422 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02672005 0,13107847 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02672005 0,13081578 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02672005 0,13055415 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02672005 0,13029356 ! basic amino acid transport GO:0015802 12 5 0,000 0,02672005 0,13003402 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02672005 0,1297755 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02672005 0,12951801 ! actin nucleation GO:0045010 11 5 0,000 0,02672005 0,12926154 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02672005 0,12900608 ! depurination GO:0045007 5 5 0,000 0,02672005 0,12875163 ! depyrimidination GO:0045008 10 5 0,000 0,02672005 0,12849818 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02672005 0,12824573 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02672005 0,12799427 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02672005 0,12774379 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02672005 0,12749429 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02672005 0,12724576 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02672005 0,1269982 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02672005 0,1267516 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02672005 0,12650596 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02672005 0,12626127 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02672005 0,12601752 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02672005 0,12577471 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02672005 0,12553284 ! response to arsenic GO:0046685 11 5 0,000 0,02672005 0,12529189 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02672005 0,12505187 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02672005 0,12481276 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02672005 0,12457457 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02672005 0,12433729 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02672005 0,1241009 ! response to mercury ion GO:0046689 8 5 0,000 0,02672005 0,12386542 ! response to cadmium ion GO:0046686 7 5 0,000 0,02672005 0,12363083 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02672005 0,12339712 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02672005 0,12316429 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02672005 0,12293235 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02672005 0,12270127 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02672005 0,12247106 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02672005 0,12224172 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02672005 0,12201323 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02672005 0,12178559 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02672005 0,1215588 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02672005 0,12133285 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02672005 0,12110775 ! embryonic cleavage GO:0040016 6 5 0,000 0,02672005 0,12088347 ! peroxisome fission GO:0016559 5 5 0,000 0,02672005 0,12066003 ! histone demethylation GO:0016577 13 5 0,000 0,02672005 0,12043741 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02672005 0,12021561 ! mitotic recombination GO:0006312 9 5 0,000 0,02672005 0,11999462 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02672005 0,11977445 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02672005 0,11955508 ! metaphase plate congression GO:0051310 7 5 0,000 0,02672005 0,11933652 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02672005 0,11911875 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02672005 0,11890178 ! enteric nervous system development GO:0048484 8 5 0,000 0,02672005 0,11868559 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02672005 0,11847019 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02672005 0,11825557 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02672005 0,11804173 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02672005 0,11782866 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02672005 0,11761635 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02672005 0,11740481 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02672005 0,11719403 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02672005 0,11698401 ! metaphase GO:0051323 11 5 0,000 0,02672005 0,11677473 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02672005 0,11656621 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02672005 0,11635842 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02672005 0,11615138 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02672005 0,11594507 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02672005 0,1157395 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02672005 0,11553465 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02672005 0,11533052 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02672005 0,11512712 ! response to redox state GO:0051775 6 5 0,000 0,02672005 0,11492443 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02672005 0,11472245 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02672005 0,11452119 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02672005 0,11432062 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02672005 0,11412076 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02672005 0,1139216 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02672005 0,11372313 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02672005 0,11352535 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02672005 0,11332826 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02672005 0,11313185 ! striatum development GO:0021756 14 5 0,000 0,02672005 0,11293612 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02672005 0,11274106 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02672005 0,11254668 ! glial cell migration GO:0008347 10 5 0,000 0,02672005 0,11235297 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02672005 0,11215992 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02672005 0,11196754 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02672005 0,11177581 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02672005 0,11158475 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02672005 0,11139433 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02672005 0,11120456 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02672005 0,11101544 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02672005 0,11082695 ! neuroprotection GO:0043526 8 5 0,000 0,02672005 0,11063911 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02672005 0,11045191 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02672005 0,11026533 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02672005 0,11007939 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02672005 0,10989407 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02672005 0,10970937 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02672005 0,1095253 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02672005 0,10934184 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02672005 0,10915899 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02672005 0,10897675 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02672005 0,10879513 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02672005 0,1086141 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02672005 0,10843368 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02672005 0,10825386 ! spindle assembly GO:0051225 6 5 0,000 0,02672005 0,10807463 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02672005 0,10789599 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02672005 0,10771795 ! drug metabolic process GO:0017144 7 5 0,000 0,02672005 0,10754049 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02672005 0,10736361 ! organ regeneration GO:0031100 7 5 0,000 0,02672005 0,10718732 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02672005 0,1070116 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02672005 0,10683646 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02782866 0,11108729 ! icosanoid metabolic process GO:0006690 92 48 1,000 0,02782866 0,11090607 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02891153 0,11503397 ! regulation of ossification GO:0030278 123 50 1,000 0,03001103 0,11921456 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,03001103 0,11902103 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03112697 0,12324667 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03197821 0,12641223 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03197821 0,12620801 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03197821 0,12600445 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03197821 0,12580155 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03197821 0,12559929 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03197821 0,12539769 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03197821 0,12519673 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03197821 0,12499642 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03197821 0,12479674 ! response to oxygen radical GO:0000305 11 6 0,000 0,03197821 0,1245977 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03197821 0,1243993 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03197821 0,12420153 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03197821 0,12400438 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03197821 0,12380786 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03197821 0,12361196 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03197821 0,12341668 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03197821 0,12322202 ! forebrain regionalization GO:0021871 9 6 0,000 0,03197821 0,12302797 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03197821 0,12283453 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03197821 0,1226417 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03197821 0,12244947 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03197821 0,12225784 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03197821 0,12206681 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03197821 0,12187638 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03197821 0,12168654 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03197821 0,1214973 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03197821 0,12130864 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03197821 0,12112056 ! malate metabolic process GO:0006108 13 6 0,000 0,03197821 0,12093307 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03197821 0,12074615 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03197821 0,12055982 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03197821 0,12037405 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03197821 0,12018886 ! protein refolding GO:0042026 15 6 0,000 0,03197821 0,12000424 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03197821 0,11982019 ! opsonization GO:0008228 8 6 0,000 0,03197821 0,11963669 ! mating behavior GO:0007617 7 6 0,000 0,03197821 0,11945376 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03197821 0,11927139 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03197821 0,11908957 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03197821 0,11890831 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03197821 0,1187276 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03197821 0,11854744 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03197821 0,11836782 ! toxin metabolic process GO:0009404 11 6 0,000 0,03197821 0,11818875 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03197821 0,11801021 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03197821 0,11783222 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03197821 0,11765476 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03197821 0,11747784 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03197821 0,11730144 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03197821 0,11712558 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03197821 0,11695024 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03197821 0,11677543 ! thymic T cell selection GO:0045061 16 6 0,000 0,03197821 0,11660114 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03197821 0,11642736 ! protein lipoylation GO:0009249 10 6 0,000 0,03197821 0,11625411 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03197821 0,11608137 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03197821 0,11590914 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03197821 0,11573742 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03197821 0,11556621 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03197821 0,11539551 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03197821 0,11522531 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03197821 0,11505561 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03197821 0,11488641 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03197821 0,11471771 ! hyperosmotic response GO:0006972 10 6 0,000 0,03197821 0,1145495 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03197821 0,11438179 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03197821 0,11421456 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03197821 0,11404783 ! urea metabolic process GO:0019627 7 6 0,000 0,03197821 0,11388158 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03197821 0,11371581 ! neutrophil activation GO:0042119 7 6 0,000 0,03197821 0,11355052 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03197821 0,11338572 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03197821 0,11322139 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03197821 0,11305754 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03197821 0,11289416 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03197821 0,11273126 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03197821 0,11256882 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03197821 0,11240685 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03197821 0,11224535 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03197821 0,11208431 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03197821 0,11192373 ! carnitine transport GO:0015879 10 6 0,000 0,03197821 0,11176361 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03197821 0,11160394 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03197821 0,11144474 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03197821 0,11128598 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03197821 0,11112768 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03197821 0,11096983 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03197821 0,11081243 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03197821 0,11065547 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03197821 0,11049895 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03197821 0,11034288 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03197821 0,11018725 ! neural nucleus development GO:0048857 19 6 0,000 0,03197821 0,11003206 ! response to UV-C GO:0010225 14 6 0,000 0,03197821 0,1098773 ! astrocyte development GO:0014002 16 6 0,000 0,03197821 0,10972298 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03197821 0,10956909 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03197821 0,10941563 ! interaction with symbiont GO:0051702 14 6 0,000 0,03197821 0,1092626 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03197821 0,10911 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03197821 0,10895783 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03197821 0,10880607 ! response to copper ion GO:0046688 10 6 0,000 0,03197821 0,10865474 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03197821 0,10850383 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03197821 0,10835334 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03197821 0,10820327 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03197821 0,10805361 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03197821 0,10790437 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03197821 0,10775553 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03197821 0,10760711 ! hair follicle maturation GO:0048820 8 6 0,000 0,03197821 0,10745909 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03197821 0,10731148 ! Schwann cell development GO:0014044 15 6 0,000 0,03197821 0,10716428 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03197821 0,10701748 ! response to pheromone GO:0019236 6 6 0,000 0,03197821 0,10687108 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03197821 0,10672508 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03197821 0,10657948 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03197821 0,10643428 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03197821 0,10628947 ! subpallium development GO:0021544 15 6 0,000 0,03197821 0,10614506 ! neural tube patterning GO:0021532 8 6 0,000 0,03197821 0,10600103 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03197821 0,1058574 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03197821 0,10571416 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03197821 0,1055713 ! G2 phase GO:0051319 16 6 0,000 0,03197821 0,10542883 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03197821 0,10528674 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03197821 0,10514503 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03197821 0,10500371 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03197821 0,10486277 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03197821 0,1047222 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03197821 0,10458201 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03197821 0,10444219 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03197821 0,10430275 ! receptor internalization GO:0031623 11 6 0,000 0,03197821 0,10416368 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03197821 0,10402498 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03197821 0,10388665 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03197821 0,10374869 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03197821 0,10361109 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03197821 0,10347386 ! protein deubiquitination GO:0016579 16 6 0,000 0,03197821 0,10333699 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03197821 0,10320048 ! protein destabilization GO:0031648 9 6 0,000 0,03197821 0,10306433 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03197821 0,10292854 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03197821 0,10279311 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03197821 0,10265803 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03197821 0,10252331 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03197821 0,10238894 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03197821 0,10225492 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03197821 0,10212126 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03197821 0,10198794 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03197821 0,10185497 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03197821 0,10172234 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03197821 0,10159007 ! neural plate development GO:0001840 9 6 0,000 0,03197821 0,10145813 ! catecholamine transport GO:0051937 9 6 0,000 0,03197821 0,10132654 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03197821 0,10119529 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03197821 0,10106437 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03197821 0,1009338 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03197821 0,10080356 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03197821 0,10067366 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03197821 0,10054409 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03197821 0,10041486 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03197821 0,10028596 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03197821 0,10015739 GO:0055081|anion homeostasis, ! Notch signaling pathway GO:0007219 111 52 1,000 0,03225914 0,10090791 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,03225914 0,10077887 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03225914 0,10065017 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,03340733 0,10409961 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,03340733 0,103967 ! vesicle organization GO:0016050 127 53 1,000 0,03340733 0,10383473 ! synapse organization GO:0050808 102 53 1,000 0,03340733 0,10370279 ! membrane fusion GO:0006944 122 54 1,000 0,03457133 0,10717989 ! covalent chromatin modification GO:0016569 115 54 1,000 0,03457133 0,10704405 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,03457133 0,10690855 ! protein amino acid lipidation GO:0006497 109 54 1,000 0,03457133 0,10677339 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,03575094 0,11027721 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03694597 0,11381967 ! tRNA transcription GO:0009304 17 7 0,000 0,03720811 0,11448288 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03720811 0,11433888 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03720811 0,11419523 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03720811 0,11405195 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03720811 0,11390903 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03720811 0,11376647 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03720811 0,11362426 ! sleep GO:0030431 16 7 0,000 0,03720811 0,11348241 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03720811 0,11334091 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03720811 0,11319976 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03720811 0,11305896 ! prostate gland development GO:0030850 14 7 0,000 0,03720811 0,11291852 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03720811 0,11277842 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03720811 0,11263867 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03720811 0,11249927 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03720811 0,11236021 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03720811 0,11222149 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03720811 0,11208312 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03720811 0,11194508 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03720811 0,11180739 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03720811 0,11167003 ! glycolipid transport GO:0046836 11 7 0,000 0,03720811 0,11153301 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03720811 0,11139633 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03720811 0,11125998 ! neuron adhesion GO:0007158 14 7 0,000 0,03720811 0,11112397 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03720811 0,11098829 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03720811 0,11085293 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03720811 0,11071791 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03720811 0,11058322 ! mRNA stabilization GO:0048255 18 7 0,000 0,03720811 0,11044885 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03720811 0,11031481 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03720811 0,1101811 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03720811 0,11004771 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03720811 0,10991464 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03720811 0,10978189 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03720811 0,10964947 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03720811 0,10951736 ! rhythmic behavior GO:0007622 17 7 0,000 0,03720811 0,10938557 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03720811 0,10925409 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03720811 0,10912294 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03720811 0,10899209 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03720811 0,10886156 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03720811 0,10873135 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03720811 0,10860144 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03720811 0,10847185 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03720811 0,10834256 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03720811 0,10821358 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03720811 0,10808491 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03720811 0,10795654 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03720811 0,10782848 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03720811 0,10770072 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03720811 0,10757326 ! spinal cord patterning GO:0021511 14 7 0,000 0,03720811 0,10744611 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03720811 0,10731925 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03720811 0,1071927 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03720811 0,10706644 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03720811 0,10694048 ! adrenal gland development GO:0030325 17 7 0,000 0,03720811 0,10681481 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03720811 0,10668944 ! ovulation GO:0030728 10 7 0,000 0,03720811 0,10656437 ! adenohypophysis development GO:0021984 11 7 0,000 0,03720811 0,10643959 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03720811 0,1063151 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03720811 0,1061909 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03720811 0,10606699 ! microtubule nucleation GO:0007020 21 7 0,000 0,03720811 0,10594336 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03720811 0,10582003 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03720811 0,10569698 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03720811 0,10557422 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03720811 0,10545175 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03720811 0,10532956 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03720811 0,10520765 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03720811 0,10508602 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03720811 0,10496467 ! galactose metabolic process GO:0006012 13 7 0,000 0,03720811 0,10484361 ! vesicle fusion GO:0006906 20 7 0,000 0,03720811 0,10472282 ! response to dietary excess GO:0002021 8 7 0,000 0,03720811 0,10460231 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03720811 0,10448208 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03720811 0,10436212 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03720811 0,10424244 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03720811 0,10412303 ! organ growth GO:0035265 15 7 0,000 0,03720811 0,1040039 ! nucleoside transport GO:0015858 11 7 0,000 0,03720811 0,10388504 ! nucleoside salvage GO:0043174 11 7 0,000 0,03720811 0,10376645 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03720811 0,10364813 ! male sex determination GO:0030238 15 7 0,000 0,03720811 0,10353008 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03720811 0,10341229 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03720811 0,10329478 ! parturition GO:0007567 16 7 0,000 0,03720811 0,10317753 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03720811 0,10306055 ! rRNA modification GO:0000154 14 7 0,000 0,03720811 0,10294384 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03720811 0,10282738 ! spindle checkpoint GO:0031577 16 7 0,000 0,03720811 0,10271119 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03720811 0,10259527 ! monocyte differentiation GO:0030224 16 7 0,000 0,03720811 0,1024796 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03720811 0,1023642 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03720811 0,10224905 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03720811 0,10213416 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03720811 0,10201954 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03720811 0,10190516 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03720811 0,10179105 ! fibrinolysis GO:0042730 11 7 0,000 0,03720811 0,10167719 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03720811 0,10156358 ! eating behavior GO:0042755 8 7 0,000 0,03720811 0,10145023 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03720811 0,10133713 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03720811 0,10122428 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03720811 0,10111169 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03720811 0,10099934 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03720811 0,10088724 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03720811 0,1007754 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03720811 0,10066379 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03720811 0,10055244 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03720811 0,10044133 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03720811 0,10033047 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03720811 0,10021985 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03720811 0,10010948 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03720811 0,09999935 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03720811 0,09988946 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03720811 0,09977981 ! histone ubiquitination GO:0016574 9 7 0,000 0,03720811 0,0996704 ! regulation of meiosis GO:0040020 12 7 0,000 0,03720811 0,09956123 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03720811 0,0994523 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03720811 0,09934361 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03720811 0,09923516 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03720811 0,09912694 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03720811 0,09901896 ! transcription termination GO:0006353 14 7 0,000 0,03720811 0,09891121 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03720811 0,0988037 ! anaphase GO:0051322 18 7 0,000 0,03720811 0,09869642 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 19 7 0,000 0,03720811 0,09858938 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03720811 0,09848256 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03720811 0,09837598 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03720811 0,09826963 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03720811 0,09816351 ! diuresis GO:0030146 12 7 0,000 0,03720811 0,09805761 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03720811 0,09795195 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03720811 0,09784651 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03720811 0,0977413 ! antibiotic transport GO:0042891 9 7 0,000 0,03720811 0,09763631 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03720811 0,09753155 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03720811 0,09742702 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03720811 0,09732271 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03720811 0,09721862 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03720811 0,09711475 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03720811 0,09701111 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03720811 0,09690768 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03720811 0,09680448 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03720811 0,0967015 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03720811 0,09659873 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03720811 0,09649619 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03720811 0,09639386 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03720811 0,09629174 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03720811 0,09618985 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03720811 0,09608817 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03720811 0,0959867 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03720811 0,09588545 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03720811 0,09578441 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03720811 0,09568359 ! muscle adaptation GO:0043500 13 7 0,000 0,03720811 0,09558297 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03720811 0,09548257 ! retina homeostasis GO:0001895 12 7 0,000 0,03720811 0,09538238 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03720811 0,0952824 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03720811 0,09518262 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03720811 0,09508306 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03720811 0,09498371 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,03815621 0,09730231 ! muscle fiber development GO:0048747 131 57 1,000 0,03815621 0,09720085 ! heart morphogenesis GO:0003007 105 57 1,000 0,03815621 0,0970996 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,03815621 0,09699856 ! regulation of actin filament length GO:0030832 118 58 1,000 0,03938146 0,10000927 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 0,03938146 0,09990542 ! aging GO:0007568 112 58 1,000 0,03938146 0,09980178 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,03938146 0,09969836 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03938146 0,09959515 ! maintenance of location GO:0051235 124 58 1,000 0,03938146 0,09949216 ! establishment of organelle localization GO:0051656 122 59 1,000 0,04062154 0,10251903 ! regulation of endocytosis GO:0030100 104 60 1,000 0,04187624 0,10557654 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,0424099 0,10681173 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,0424099 0,10670173 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,0424099 0,10659196 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,0424099 0,10648241 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0424099 0,10637308 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0424099 0,10626398 ! male meiosis GO:0007140 9 8 0,000 0,0424099 0,1061551 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,0424099 0,10604645 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,0424099 0,10593802 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,0424099 0,10582981 ! meiotic prophase I GO:0007128 14 8 0,000 0,0424099 0,10572182 ! response to zinc ion GO:0010043 12 8 0,000 0,0424099 0,10561405 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0424099 0,1055065 ! oligopeptide transport GO:0006857 16 8 0,000 0,0424099 0,10539917 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,0424099 0,10529205 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,0424099 0,10518516 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,0424099 0,10507848 ! signal peptide processing GO:0006465 12 8 0,000 0,0424099 0,10497202 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,0424099 0,10486577 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,0424099 0,10475974 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0424099 0,10465392 ! succinate metabolic process GO:0006105 17 8 0,000 0,0424099 0,10454832 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,0424099 0,10444293 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,0424099 0,10433775 ! estrogen metabolic process GO:0008210 17 8 0,000 0,0424099 0,10423278 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,0424099 0,10412802 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0424099 0,10402348 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,0424099 0,10391914 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0424099 0,10381501 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0424099 0,10371109 ! reflex GO:0060004 17 8 0,000 0,0424099 0,10360738 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0424099 0,10350388 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,0424099 0,10340058 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0424099 0,10329749 ! pigment granule organization GO:0048753 17 8 0,000 0,0424099 0,1031946 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0424099 0,10309192 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,0424099 0,10298945 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,0424099 0,10288717 ! astrocyte differentiation GO:0048708 19 8 0,000 0,0424099 0,1027851 ! histidine catabolic process GO:0006548 10 8 0,000 0,0424099 0,10268323 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0424099 0,10258157 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,0424099 0,1024801 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,0424099 0,10237884 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,0424099 0,10227777 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,0424099 0,10217691 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,0424099 0,10207624 ! melanin metabolic process GO:0006582 17 8 0,000 0,0424099 0,10197577 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,0424099 0,1018755 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,0424099 0,10177542 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,0424099 0,10167555 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0424099 0,10157586 ! macrophage activation GO:0042116 13 8 0,000 0,0424099 0,10147638 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0424099 0,10137709 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,0424099 0,10127799 ! purine salvage GO:0043101 12 8 0,000 0,0424099 0,10117908 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,0424099 0,10108037 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0424099 0,10098185 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,0424099 0,10088353 ! osteoblast development GO:0002076 17 8 0,000 0,0424099 0,10078539 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,0424099 0,10068745 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,0424099 0,10058969 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,0424099 0,10049213 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,0424099 0,10039475 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0424099 0,10029756 ! response to UV-B GO:0010224 17 8 0,000 0,0424099 0,10020056 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,0424099 0,10010375 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0424099 0,10000713 ! intermediate filament organization GO:0045109 12 8 0,000 0,0424099 0,09991069 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,0424099 0,09981443 ! cellular extravasation GO:0045123 13 8 0,000 0,0424099 0,09971837 ! response to antibiotic GO:0046677 11 8 0,000 0,0424099 0,09962248 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,0424099 0,09952678 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,0424099 0,09943127 ! DNA topological change GO:0006265 12 8 0,000 0,0424099 0,09933594 ! response to tropane GO:0014073 15 8 0,000 0,0424099 0,09924079 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,0424099 0,09914582 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,0424099 0,09905103 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0424099 0,09895643 ! mast cell activation GO:0045576 14 8 0,000 0,0424099 0,09886201 ! multicellular organismal aging GO:0010259 20 8 0,000 0,0424099 0,09876776 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,0424099 0,0986737 ! gas homeostasis GO:0033483 14 8 0,000 0,0424099 0,09857981 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,0424099 0,0984861 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,0424099 0,09839258 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,0424099 0,09829922 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0424099 0,09820605 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0424099 0,09811305 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,0424099 0,09802023 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0424099 0,09792758 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,0424099 0,09783511 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,0424099 0,09774281 ! intracellular lipid transport GO:0032365 16 8 0,000 0,0424099 0,09765069 ! response to tumor cell GO:0002347 16 8 0,000 0,0424099 0,09755874 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0424099 0,09746696 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,0424099 0,09737536 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,0424099 0,09728393 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,0424099 0,09719267 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0424099 0,09710158 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,0424099 0,09701066 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,0424099 0,09691991 ! hormone catabolic process GO:0042447 17 8 0,000 0,0424099 0,09682933 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,0424099 0,09673892 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,0424099 0,09664868 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,0424099 0,0965586 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,0424099 0,0964687 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0424099 0,09637896 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,0424099 0,09628939 ! adult feeding behavior GO:0008343 10 8 0,000 0,0424099 0,09619998 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,0424099 0,09611074 ! ATP catabolic process GO:0006200 11 8 0,000 0,0424099 0,09602167 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0424099 0,09593276 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,0424099 0,09584402 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0424099 0,09575544 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,0424099 0,09566702 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,0424099 0,09557877 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,0424099 0,09549067 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,0424099 0,09540275 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,0424099 0,09531498 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,0424099 0,09522737 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0424099 0,09513993 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,0424099 0,09505264 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,0424099 0,09496552 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0424099 0,09487855 ! protein prenylation GO:0018342 21 8 0,000 0,0424099 0,09479175 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0424099 0,0947051 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,0424099 0,09461861 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,0424099 0,09453228 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,0424099 0,09444611 ! regulation of cellular component size GO:0032535 125 61 1,000 0,04314538 0,09599651 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,04442876 0,09876202 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,04442876 0,09867224 ! regulation of mitosis GO:0007088 112 63 1,000 0,04572619 0,10146148 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 0,04572619 0,10136941 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,04572619 0,10127751 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,0470375 0,1040875 ! axon extension GO:0048675 16 9 0,000 0,04758373 0,10520095 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04758373 0,10510584 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04758373 0,10501089 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04758373 0,10491611 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04758373 0,10482151 GO:0006740|NADPH regeneration, ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04758373 0,10472708 ! reproductive behavior GO:0019098 22 9 0,000 0,04758373 0,10463281 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04758373 0,10453872 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04758373 0,10444479 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04758373 0,10435104 ! UTP metabolic process GO:0046051 10 9 0,000 0,04758373 0,10425745 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04758373 0,10416403 ! artery development GO:0060840 25 9 0,000 0,04758373 0,10407077 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04758373 0,10397769 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04758373 0,10388477 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04758373 0,10379201 ! equilibrioception GO:0050957 20 9 0,000 0,04758373 0,10369942 ! chemosensory behavior GO:0007635 21 9 0,000 0,04758373 0,103607 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04758373 0,10351474 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04758373 0,10342265 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04758373 0,10333071 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04758373 0,10323895 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04758373 0,10314734 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04758373 0,1030559 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04758373 0,10296462 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04758373 0,1028735 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04758373 0,10278254 ! protein targeting to ER GO:0045047 25 9 0,000 0,04758373 0,10269174 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04758373 0,10260111 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04758373 0,10251063 ! T cell selection GO:0045058 27 9 0,000 0,04758373 0,10242031 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04758373 0,10233015 ! glycine catabolic process GO:0006546 15 9 0,000 0,04758373 0,10224015 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04758373 0,10215031 ! endosome organization GO:0007032 20 9 0,000 0,04758373 0,10206063 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04758373 0,1019711 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04758373 0,10188173 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04758373 0,10179252 ! mannose metabolic process GO:0006013 13 9 0,000 0,04758373 0,10170346 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04758373 0,10161456 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04758373 0,10152581 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04758373 0,10143722 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04758373 0,10134878 ! receptor clustering GO:0043113 20 9 0,000 0,04758373 0,1012605 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04758373 0,10117237 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04758373 0,10108439 ! retinol metabolic process GO:0042572 20 9 0,000 0,04758373 0,10099657 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04758373 0,1009089 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04758373 0,10082138 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04758373 0,10073402 ! macrophage differentiation GO:0030225 15 9 0,000 0,04758373 0,1006468 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04758373 0,10055973 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04758373 0,10047282 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04758373 0,10038606 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04758373 0,10029944 ! response to amine stimulus GO:0014075 13 9 0,000 0,04758373 0,10021298 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04758373 0,10012666 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04758373 0,10004049 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04758373 0,09995447 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04758373 0,0998686 ! renal water homeostasis GO:0003091 15 9 0,000 0,04758373 0,09978288 ! postreplication repair GO:0006301 25 9 0,000 0,04758373 0,0996973 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04758373 0,09961187 ! icosanoid secretion GO:0032309 15 9 0,000 0,04758373 0,09952659 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04758373 0,09944145 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04758373 0,09935646 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04758373 0,09927161 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04758373 0,09918691 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04758373 0,09910235 ! sterol catabolic process GO:0016127 14 9 0,000 0,04758373 0,09901793 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04758373 0,09893366 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04758373 0,09884954 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04758373 0,09876555 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04758373 0,09868171 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04758373 0,09859801 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04758373 0,09851445 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04758373 0,09843104 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04758373 0,09834776 ! purine base metabolic process GO:0006144 25 9 0,000 0,04758373 0,09826463 ! pigment granule transport GO:0051904 17 9 0,000 0,04758373 0,09818163 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04758373 0,09809878 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04758373 0,09801607 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04758373 0,09793349 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04758373 0,09785106 ! mitochondrion localization GO:0051646 18 9 0,000 0,04758373 0,09776876 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,04836248 0,09928532 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 1,000 0,04836248 0,09920196 ! ear development GO:0043583 114 66 1,000 0,04970095 0,10186194 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,04970095 0,10177656 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,04970095 0,10169132 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,05105274 0,10436975 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,05241767 0,10707054 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,05241767 0,10698109 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,05241767 0,10689179 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05272975 0,10743852 ! regulation of developmental growth GO:0048638 16 10 0,000 0,05272975 0,10734899 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05272975 0,10725961 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05272975 0,10717037 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05272975 0,10708129 ! associative learning GO:0008306 21 10 0,000 0,05272975 0,10699235 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05272975 0,10690356 ! phosphate transport GO:0006817 24 10 0,000 0,05272975 0,10681492 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05272975 0,10672642 ! CTP metabolic process GO:0046036 11 10 0,000 0,05272975 0,10663807 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,05272975 0,10654987 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05272975 0,10646181 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05272975 0,1063739 ! social behavior GO:0035176 29 10 0,000 0,05272975 0,10628613 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05272975 0,10619851 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05272975 0,10611103 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05272975 0,10602369 ! androgen metabolic process GO:0008209 17 10 0,000 0,05272975 0,1059365 ! phospholipid efflux GO:0033700 19 10 0,000 0,05272975 0,10584946 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05272975 0,10576255 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05272975 0,10567579 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05272975 0,10558917 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05272975 0,10550269 ! lung alveolus development GO:0048286 26 10 0,000 0,05272975 0,10541636 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05272975 0,10533016 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05272975 0,10524411 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05272975 0,10515819 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05272975 0,10507242 ! endoderm development GO:0007492 18 10 0,000 0,05272975 0,10498679 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05272975 0,10490129 ! arginine catabolic process GO:0006527 17 10 0,000 0,05272975 0,10481594 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05272975 0,10473072 ! proline metabolic process GO:0006560 13 10 0,000 0,05272975 0,10464564 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05272975 0,1045607 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05272975 0,1044759 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05272975 0,10439124 ! V(D)J recombination GO:0033151 34 10 0,000 0,05272975 0,10430671 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05272975 0,10422232 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05272975 0,10413807 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05272975 0,10405395 ! B cell proliferation GO:0042100 19 10 0,000 0,05272975 0,10396997 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05272975 0,10388612 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05272975 0,10380241 ! multicellular organism growth GO:0035264 19 10 0,000 0,05272975 0,10371883 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05272975 0,10363539 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05272975 0,10355208 ! ruffle organization GO:0031529 17 10 0,000 0,05272975 0,10346891 ! epithelial cell development GO:0002064 21 10 0,000 0,05272975 0,10338586 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05272975 0,10330296 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05272975 0,10322018 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05272975 0,10313754 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05272975 0,10305503 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05272975 0,10297265 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05272975 0,10289041 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,05272975 0,10280829 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05272975 0,10272631 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05272975 0,10264445 ! protein heterooligomerization GO:0051291 17 10 0,000 0,05272975 0,10256273 ! brain morphogenesis GO:0048854 23 10 0,000 0,05272975 0,10248114 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05272975 0,10239967 ! segment specification GO:0007379 15 10 0,000 0,05272975 0,10231834 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05272975 0,10223713 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05272975 0,10215606 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05272975 0,10207511 ! response to dsRNA GO:0043331 23 10 0,000 0,05272975 0,10199429 ! DNA ligation GO:0006266 18 10 0,000 0,05272975 0,1019136 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05272975 0,10183303 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05272975 0,1017526 ! melanosome localization GO:0032400 16 10 0,000 0,05272975 0,10167229 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05272975 0,1015921 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05272975 0,10151205 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05272975 0,10143212 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05272975 0,10135231 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05272975 0,10127263 ! induction of an organ GO:0001759 17 10 0,000 0,05272975 0,10119308 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05272975 0,10111365 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05272975 0,10103434 ! protein sumoylation GO:0016925 17 10 0,000 0,05272975 0,10095516 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05272975 0,10087611 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05272975 0,10079717 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05272975 0,10071836 ! salivary gland development GO:0007431 28 10 0,000 0,05272975 0,10063968 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05272975 0,10056111 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05272975 0,10048267 ! midbrain development GO:0030901 14 10 0,000 0,05272975 0,10040436 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05272975 0,10032616 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05272975 0,10024808 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05272975 0,10017013 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05272975 0,1000923 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05272975 0,10001459 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05272975 0,099937 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05272975 0,09985953 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05272975 0,09978217 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05272975 0,09970494 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05272975 0,09962783 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05272975 0,09955084 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05272975 0,09947397 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05272975 0,09939721 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05272975 0,09932058 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05272975 0,09924406 ! response to nicotine GO:0035094 20 10 0,000 0,05272975 0,09916766 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05272975 0,09909138 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05272975 0,09901521 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,05379554 0,10093895 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,05379554 0,10086149 ! single fertilization GO:0007338 83 69 1,000 0,05379554 0,10078414 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,0551862 0,10331025 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,05658944 0,10585606 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05784812 0,10812773 ! respiratory burst GO:0045730 17 11 0,000 0,05784812 0,10804507 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05784812 0,10796253 ! neuron fate specification GO:0048665 18 11 0,000 0,05784812 0,10788011 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05784812 0,10779782 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05784812 0,10771566 ! thyroid gland development GO:0030878 26 11 0,000 0,05784812 0,10763362 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,05784812 0,10755171 ! synapsis GO:0007129 14 11 0,000 0,05784812 0,10746992 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05784812 0,10738826 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05784812 0,10730672 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05784812 0,1072253 ! response to pain GO:0048265 27 11 0,000 0,05784812 0,10714401 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05784812 0,10706284 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05784812 0,10698179 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05784812 0,10690087 ! bone resorption GO:0045453 16 11 0,000 0,05784812 0,10682007 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05784812 0,10673939 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,05784812 0,10665883 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05784812 0,10657839 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05784812 0,10649808 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05784812 0,10641788 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05784812 0,10633781 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05784812 0,10625785 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05784812 0,10617802 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05784812 0,10609831 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05784812 0,10601871 ! UV protection GO:0009650 20 11 0,000 0,05784812 0,10593924 ! adult heart development GO:0007512 16 11 0,000 0,05784812 0,10585989 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05784812 0,10578065 ! macroautophagy GO:0016236 19 11 0,000 0,05784812 0,10570153 ! temperature homeostasis GO:0001659 18 11 0,000 0,05784812 0,10562253 ! behavioral fear response GO:0001662 27 11 0,000 0,05784812 0,10554365 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05784812 0,10546489 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05784812 0,10538624 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05784812 0,10530771 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05784812 0,1052293 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05784812 0,105151 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05784812 0,10507282 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05784812 0,10499476 ! regulation of organ growth GO:0046620 14 11 0,000 0,05784812 0,10491681 ! pigment granule localization GO:0051875 20 11 0,000 0,05784812 0,10483898 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05784812 0,10476127 ! vasoconstriction GO:0042310 20 11 0,000 0,05784812 0,10468366 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05784812 0,10460618 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05784812 0,10452881 ! embryonic axis specification GO:0000578 19 11 0,000 0,05784812 0,10445155 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05784812 0,10437441 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05784812 0,10429738 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05784812 0,10422046 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05784812 0,10414366 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05784812 0,10406697 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05784812 0,10399039 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05784812 0,10391393 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05784812 0,10383758 ! prophase GO:0051324 17 11 0,000 0,05784812 0,10376134 ! nucleosome positioning GO:0016584 15 11 0,000 0,05784812 0,10368521 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05784812 0,1036092 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05784812 0,10353329 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05784812 0,1034575 ! apical protein localization GO:0045176 18 11 0,000 0,05784812 0,10338182 ! acid secretion GO:0046717 20 11 0,000 0,05784812 0,10330625 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05784812 0,10323079 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05784812 0,10315544 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05784812 0,10308019 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05784812 0,10300506 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05784812 0,10293004 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05784812 0,10285513 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05784812 0,10278032 ! cholesterol efflux GO:0033344 21 11 0,000 0,05784812 0,10270563 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05784812 0,10263104 ! oocyte development GO:0048599 20 11 0,000 0,05784812 0,10255657 ! germ cell migration GO:0008354 26 11 0,000 0,05784812 0,10248219 ! embryonic gut development GO:0048566 19 11 0,000 0,05784812 0,10240793 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05784812 0,10233378 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05784812 0,10225973 ! activation of innate immune response GO:0002218 16 11 0,000 0,05784812 0,10218579 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05784812 0,10211196 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05784812 0,10203823 ! lysogeny GO:0030069 22 11 0,000 0,05784812 0,10196461 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05784812 0,10189109 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05784812 0,10181769 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05784812 0,10174438 ! regulation of embryonic development GO:0045995 35 11 0,000 0,05784812 0,10167118 ! appendage morphogenesis GO:0035107 150 72 1,000 0,05800512 0,10187383 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,05800512 0,10180065 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,05800512 0,10172757 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,05800512 0,10165459 ! appendage development GO:0048736 151 73 1,000 0,05943304 0,10408237 GO:0060173|limb development, ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,06232494 0,10906865 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,06232494 0,10899057 ! axon guidance GO:0007411 162 75 1,000 0,06232494 0,10891261 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06293897 0,109907 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06293897 0,10982849 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,06293897 0,1097501 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06293897 0,10967182 ! virus-host interaction GO:0019048 30 12 0,000 0,06293897 0,10959365 ! mating GO:0007618 17 12 0,000 0,06293897 0,10951559 ! protein complex disassembly GO:0043241 28 12 0,000 0,06293897 0,10943765 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06293897 0,10935981 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06293897 0,10928208 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,06293897 0,10920447 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06293897 0,10912696 ! T cell proliferation GO:0042098 32 12 0,000 0,06293897 0,10904957 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06293897 0,10897228 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06293897 0,10889511 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06293897 0,10881804 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06293897 0,10874108 ! drug transport GO:0015893 16 12 0,000 0,06293897 0,10866424 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06293897 0,10858749 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06293897 0,10851086 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06293897 0,10843434 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06293897 0,10835792 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06293897 0,10828161 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06293897 0,10820541 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06293897 0,10812932 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06293897 0,10805333 ! lipid digestion GO:0044241 21 12 0,000 0,06293897 0,10797745 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06293897 0,10790168 ! entry into host cell GO:0030260 34 12 0,000 0,06293897 0,10782601 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06293897 0,10775045 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06293897 0,10767499 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06293897 0,10759964 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06293897 0,1075244 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06293897 0,10744926 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06293897 0,10737423 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06293897 0,1072993 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06293897 0,10722447 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06293897 0,10714975 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06293897 0,10707513 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06293897 0,10700062 ! cranial nerve development GO:0021545 23 12 0,000 0,06293897 0,10692621 ! fucose catabolic process GO:0019317 25 12 0,000 0,06293897 0,10685191 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06293897 0,1067777 ! histone acetylation GO:0016573 27 12 0,000 0,06293897 0,1067036 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06293897 0,10662961 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06293897 0,10655571 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06293897 0,10648192 ! zymogen activation GO:0031638 18 12 0,000 0,06293897 0,10640823 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06293897 0,10633464 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06293897 0,10626116 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06293897 0,10618777 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06293897 0,10611449 ! oocyte differentiation GO:0009994 21 12 0,000 0,06293897 0,10604131 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06293897 0,10596822 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06293897 0,10589524 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06293897 0,10582236 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06293897 0,10574958 ! defense response to fungus GO:0050832 15 12 0,000 0,06293897 0,1056769 ! developmental induction GO:0031128 22 12 0,000 0,06293897 0,10560432 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,06293897 0,10553184 ! response to cold GO:0009409 17 12 0,000 0,06293897 0,10545946 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06293897 0,10538718 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06293897 0,10531499 ! localization within membrane GO:0051668 26 12 0,000 0,06293897 0,10524291 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,06378858 0,10659064 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,06378858 0,10651778 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,0652638 0,10890673 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,0652638 0,10883239 ! amine catabolic process GO:0009310 136 77 1,000 0,0652638 0,10875816 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,0652638 0,10868402 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,06675041 0,11108397 ! fertilization GO:0009566 99 78 1,000 0,06675041 0,11100835 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06675041 0,11093283 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06800245 0,11293677 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06800245 0,11286004 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06800245 0,11278342 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06800245 0,11270691 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06800245 0,1126305 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06800245 0,11255419 ! peroxisomal transport GO:0043574 28 13 0,000 0,06800245 0,11247799 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06800245 0,11240188 ! cartilage condensation GO:0001502 22 13 0,000 0,06800245 0,11232589 ! organelle fusion GO:0048284 36 13 0,000 0,06800245 0,11224999 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06800245 0,1121742 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06800245 0,1120985 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06800245 0,11202292 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06800245 0,11194743 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06800245 0,11187204 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06800245 0,11179676 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06800245 0,11172158 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06800245 0,11164649 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06800245 0,11157151 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06800245 0,11149663 ! methionine metabolic process GO:0006555 31 13 0,000 0,06800245 0,11142185 ! plasma membrane organization GO:0007009 27 13 0,000 0,06800245 0,11134717 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06800245 0,11127259 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06800245 0,11119812 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06800245 0,11112374 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06800245 0,11104945 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06800245 0,11097527 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06800245 0,11090119 ! exocrine system development GO:0035272 34 13 0,000 0,06800245 0,11082721 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06800245 0,11075332 ! monoamine transport GO:0015844 21 13 0,000 0,06800245 0,11067954 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06800245 0,11060585 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06800245 0,11053226 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06800245 0,11045877 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06800245 0,11038537 ! protein homotetramerization GO:0051289 24 13 0,000 0,06800245 0,11031207 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06800245 0,11023887 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06800245 0,11016577 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06800245 0,11009277 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06800245 0,11001986 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06800245 0,10994704 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06800245 0,10987433 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,06800245 0,10980171 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06800245 0,10972918 ! histone methylation GO:0016571 29 13 0,000 0,06800245 0,10965676 ! gland morphogenesis GO:0022612 31 13 0,000 0,06800245 0,10958442 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06800245 0,10951218 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06800245 0,10944004 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06800245 0,10936799 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06800245 0,10929604 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06800245 0,10922418 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06800245 0,10915242 ! spleen development GO:0048536 24 13 0,000 0,06800245 0,10908075 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06800245 0,10900918 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06800245 0,10893769 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06800245 0,10886631 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06800245 0,10879501 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06800245 0,10872381 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06800245 0,1086527 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06800245 0,10858169 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06800245 0,10851077 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06800245 0,10843994 ! insulin secretion GO:0030073 24 13 0,000 0,06800245 0,1083692 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06800245 0,10829856 ! acrosome reaction GO:0007340 19 13 0,000 0,06800245 0,108228 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06800245 0,10815754 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06800245 0,10808717 ! blood coagulation GO:0007596 151 79 1,000 0,06824827 0,10840736 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,06824827 0,10833692 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,06824827 0,10826657 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,0697572 0,11058848 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,0697572 0,11051676 ! meiosis GO:0007126 143 81 1,000 0,07127705 0,11285148 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 1,000 0,07280765 0,11520018 ! meiotic cell cycle GO:0051321 144 82 1,000 0,07280765 0,11512562 ! rRNA transcription GO:0009303 28 14 0,000 0,07303871 0,11541629 ! regulation of S phase GO:0033261 26 14 0,000 0,07303871 0,11534168 ! water transport GO:0006833 21 14 0,000 0,07303871 0,11526717 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07303871 0,11519276 ! non-recombinational repair GO:0000726 29 14 0,000 0,07303871 0,11511844 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07303871 0,11504422 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07303871 0,11497009 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07303871 0,11489606 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07303871 0,11482212 ! lipid localization GO:0010876 32 14 0,000 0,07303871 0,11474828 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07303871 0,11467454 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07303871 0,11460089 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07303871 0,11452733 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07303871 0,11445387 ! arginine metabolic process GO:0006525 21 14 0,000 0,07303871 0,1143805 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07303871 0,11430723 ! regulation of heart rate GO:0002027 25 14 0,000 0,07303871 0,11423405 ! fear response GO:0042596 34 14 0,000 0,07303871 0,11416096 ! organic alcohol transport GO:0015850 29 14 0,000 0,07303871 0,11408797 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07303871 0,11401507 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07303871 0,11394226 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 28 14 0,000 0,07303871 0,11386955 ! bone mineralization GO:0030282 18 14 0,000 0,07303871 0,11379693 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07303871 0,1137244 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07303871 0,11365196 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07303871 0,11357962 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07303871 0,11350737 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07303871 0,11343521 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07303871 0,11336314 ! ribosome assembly GO:0042255 18 14 0,000 0,07303871 0,11329116 ! cerebellum development GO:0021549 23 14 0,000 0,07303871 0,11321928 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07303871 0,11314748 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07303871 0,11307578 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07303871 0,11300417 ! response to gamma radiation GO:0010332 30 14 0,000 0,07303871 0,11293265 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07303871 0,11286121 ! NADP metabolic process GO:0006739 24 14 0,000 0,07303871 0,11278987 ! oxygen transport GO:0015671 22 14 0,000 0,07303871 0,11271862 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07303871 0,11264746 ! male genitalia development GO:0030539 26 14 0,000 0,07303871 0,11257639 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07303871 0,11250541 ! regulation of axon extension GO:0030516 43 14 0,000 0,07303871 0,11243452 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07303871 0,11236372 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07303871 0,112293 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,07434884 0,11423536 ! hemostasis GO:0007599 165 85 1,000 0,07746238 0,11894444 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,07746238 0,11886972 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,07746238 0,1187951 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07804791 0,11961796 ! lactation GO:0007595 30 15 0,000 0,07804791 0,11954297 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,07804791 0,11946807 ! reproductive cellular process GO:0048610 22 15 0,000 0,07804791 0,11939326 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07804791 0,11931854 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07804791 0,11924392 ! superoxide anion generation GO:0042554 22 15 0,000 0,07804791 0,1191694 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07804791 0,11909496 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07804791 0,11902062 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07804791 0,11894637 ! copper ion transport GO:0006825 22 15 0,000 0,07804791 0,11887222 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07804791 0,11879815 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07804791 0,11872418 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07804791 0,1186503 ! sulfate transport GO:0008272 27 15 0,000 0,07804791 0,11857651 ! response to cAMP GO:0051591 25 15 0,000 0,07804791 0,11850282 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07804791 0,11842921 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07804791 0,1183557 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07804791 0,11828228 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07804791 0,11820895 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07804791 0,11813571 ! vesicle coating GO:0006901 38 15 0,000 0,07804791 0,11806256 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07804791 0,1179895 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07804791 0,11791653 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07804791 0,11784366 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07804791 0,11777087 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07804791 0,11769817 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07804791 0,11762556 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07804791 0,11755304 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07804791 0,11748061 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07804791 0,11740827 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07804791 0,11733602 ! histone deacetylation GO:0016575 24 15 0,000 0,07804791 0,11726386 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07804791 0,11719178 ! water homeostasis GO:0030104 28 15 0,000 0,07804791 0,1171198 ! cofactor transport GO:0051181 30 15 0,000 0,07804791 0,1170479 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07804791 0,11697609 ! muscle maintenance GO:0046716 26 15 0,000 0,07804791 0,11690437 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07804791 0,11683274 ! intestinal absorption GO:0050892 31 15 0,000 0,07804791 0,1167612 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07804791 0,11668974 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07804791 0,11661837 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07804791 0,11654709 ! cell killing GO:0001906 32 15 0,000 0,07804791 0,11647589 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07804791 0,11640478 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07804791 0,11633376 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07804791 0,11626283 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07804791 0,11619198 ! actin filament polymerization GO:0030041 27 15 0,000 0,07804791 0,11612121 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07804791 0,11605054 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07903442 0,11744591 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,08061642 0,11972397 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 1,000 0,08220825 0,12201383 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,08220825 0,12193974 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08303017 0,12308416 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08303017 0,12300952 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08303017 0,12293497 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08303017 0,12286051 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08303017 0,12278614 ! bone remodeling GO:0046849 28 16 0,000 0,08303017 0,12271186 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08303017 0,12263767 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08303017 0,12256357 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08303017 0,12248955 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08303017 0,12241563 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08303017 0,1223418 ! startle response GO:0001964 28 16 0,000 0,08303017 0,12226805 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08303017 0,1221944 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08303017 0,12212083 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08303017 0,12204735 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08303017 0,12197396 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08303017 0,12190066 ! pituitary gland development GO:0021983 30 16 0,000 0,08303017 0,12182745 ! response to osmotic stress GO:0006970 27 16 0,000 0,08303017 0,12175432 ! lysosomal transport GO:0007041 31 16 0,000 0,08303017 0,12168128 ! fructose metabolic process GO:0006000 25 16 0,000 0,08303017 0,12160833 ! L-amino acid transport GO:0015807 33 16 0,000 0,08303017 0,12153547 ! stem cell development GO:0048864 46 16 0,000 0,08303017 0,1214627 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08303017 0,12139001 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08303017 0,1213174 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08303017 0,12124489 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08303017 0,12117246 ! axon cargo transport GO:0008088 46 16 0,000 0,08303017 0,12110012 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08303017 0,12102786 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08303017 0,1209557 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,08303017 0,12088361 ! neuron recognition GO:0008038 40 16 0,000 0,08303017 0,12081161 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08303017 0,1207397 ! tissue regeneration GO:0042246 27 16 0,000 0,08303017 0,12066788 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08303017 0,12059614 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08303017 0,12052448 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08303017 0,12045291 ! biomineral formation GO:0031214 22 16 0,000 0,08303017 0,12038142 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08303017 0,12031002 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08303017 0,12023871 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08303017 0,12016748 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08303017 0,12009633 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08303017 0,12002527 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08303017 0,11995429 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08303017 0,11988339 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08303017 0,11981258 ! peptide hormone processing GO:0016486 27 16 0,000 0,08303017 0,11974185 ! regulation of DNA binding GO:0051101 167 89 1,000 0,08380975 0,12079482 ! regulation of neurological system process GO:0031644 175 89 1,000 0,08380975 0,12072359 ! ossification GO:0001503 205 91 1,000 0,08704115 0,12530437 ! gland development GO:0048732 220 91 1,000 0,08704115 0,12523058 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08798565 0,12651497 ! metencephalon development GO:0022037 32 17 0,000 0,08798565 0,12644055 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08798565 0,12636622 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08798565 0,12629197 ! signal complex assembly GO:0007172 47 17 0,000 0,08798565 0,12621781 ! filopodium assembly GO:0046847 42 17 0,000 0,08798565 0,12614374 ! endothelial cell migration GO:0043542 31 17 0,000 0,08798565 0,12606976 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08798565 0,12599586 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08798565 0,12592205 ! glial cell development GO:0021782 28 17 0,000 0,08798565 0,12584832 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08798565 0,12577468 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08798565 0,12570113 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08798565 0,12562766 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08798565 0,12555428 ! myoblast differentiation GO:0045445 50 17 0,000 0,08798565 0,12548099 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08798565 0,12540778 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,08798565 0,12533465 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08798565 0,12526162 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08798565 0,12518866 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08798565 0,12511579 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08798565 0,12504301 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08798565 0,12497031 ! membrane budding GO:0006900 42 17 0,000 0,08798565 0,12489769 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08798565 0,12482516 ! regulation of protein binding GO:0043393 33 17 0,000 0,08798565 0,12475272 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08798565 0,12468036 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08798565 0,12460808 ! genitalia development GO:0048806 32 17 0,000 0,08798565 0,12453588 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08798565 0,12446377 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08798565 0,12439174 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08798565 0,1243198 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08798565 0,12424794 ! steroid catabolic process GO:0006706 34 17 0,000 0,08798565 0,12417616 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08798565 0,12410446 ! gas transport GO:0015669 26 17 0,000 0,08798565 0,12403285 ! organic cation transport GO:0015695 32 17 0,000 0,08798565 0,12396132 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08798565 0,12388987 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08798565 0,12381851 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08798565 0,12374723 ! bone development GO:0060348 206 92 1,000 0,08867076 0,12463904 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,09030944 0,12686945 GO:0010498|proteasomal protein catabolic process, ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,09195707 0,12910983 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09291448 0,13037914 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09291448 0,13030429 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09291448 0,13022953 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09291448 0,13015486 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09291448 0,13008027 ! adult walking behavior GO:0007628 36 18 0,000 0,09291448 0,13000577 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09291448 0,12993136 ! heart looping GO:0001947 34 18 0,000 0,09291448 0,12985702 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09291448 0,12978278 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09291448 0,12970862 ! centrosome cycle GO:0007098 26 18 0,000 0,09291448 0,12963454 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09291448 0,12956055 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09291448 0,12948664 ! glycine metabolic process GO:0006544 30 18 0,000 0,09291448 0,12941282 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09291448 0,12933908 ! response to retinoic acid GO:0032526 31 18 0,000 0,09291448 0,12926542 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,09291448 0,12919185 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09291448 0,12911836 ! DNA integration GO:0015074 32 18 0,000 0,09291448 0,12904496 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,09291448 0,12897164 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09291448 0,1288984 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09291448 0,12882524 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09291448 0,12875217 ! neural crest cell migration GO:0001755 41 18 0,000 0,09291448 0,12867918 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09291448 0,12860628 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09291448 0,12853345 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09291448 0,12846071 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09291448 0,12838805 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,09291448 0,12831548 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09291448 0,12824298 ! detection of bacterium GO:0016045 22 18 0,000 0,09291448 0,12817057 ! nerve development GO:0021675 34 18 0,000 0,09291448 0,12809824 ! defense response to virus GO:0051607 43 18 0,000 0,09291448 0,12802599 ! microspike assembly GO:0030035 46 18 0,000 0,09291448 0,12795382 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09291448 0,12788173 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09291448 0,12780973 ! transcription initiation GO:0006352 171 97 1,000 0,09695211 0,13328869 ! regulation of protein localization GO:0032880 188 97 1,000 0,09695211 0,13321372 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09781682 0,1343263 ! positive regulation of translation GO:0045727 31 19 0,000 0,09781682 0,13425084 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09781682 0,13417546 ! neuron maturation GO:0042551 46 19 0,000 0,09781682 0,13410016 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09781682 0,13402495 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09781682 0,13394983 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09781682 0,13387478 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09781682 0,13379983 ! inositol metabolic process GO:0006020 33 19 0,000 0,09781682 0,13372495 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09781682 0,13365016 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09781682 0,13357545 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09781682 0,13350083 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09781682 0,13342629 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09781682 0,13335183 ! response to vitamin A GO:0033189 32 19 0,000 0,09781682 0,13327746 ! heme metabolic process GO:0042168 40 19 0,000 0,09781682 0,13320317 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09781682 0,13312896 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09781682 0,13305484 ! response to fungus GO:0009620 26 19 0,000 0,09781682 0,13298079 ! peptide cross-linking GO:0018149 39 19 0,000 0,09781682 0,13290683 ! protein export from nucleus GO:0006611 40 19 0,000 0,09781682 0,13283296 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09781682 0,13275916 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09781682 0,13268545 ! visual learning GO:0008542 38 19 0,000 0,09781682 0,13261181 ! cellular pigmentation GO:0033059 37 19 0,000 0,09781682 0,13253826 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09781682 0,13246479 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09781682 0,13239141 ! vitamin transport GO:0051180 31 19 0,000 0,09781682 0,1323181 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09781682 0,13224487 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09781682 0,13217173 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09781682 0,13209867 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09781682 0,13202568 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09781682 0,13195278 ! cilium assembly GO:0042384 38 19 0,000 0,09781682 0,13187996 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09781682 0,13180722 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,10202248 0,13739852 GO:0060538|skeletal muscle organ development, ! protein secretion GO:0009306 45 20 0,000 0,1026928 0,13822507 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1026928 0,13814896 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,1026928 0,13807293 ! positive regulation of ossification GO:0045778 50 20 0,000 0,1026928 0,13799698 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,1026928 0,13792111 ! skin development GO:0043588 42 20 0,000 0,1026928 0,13784533 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,1026928 0,13776964 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,1026928 0,13769402 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,1026928 0,13761849 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,1026928 0,13754304 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1026928 0,13746767 ! response to vitamin GO:0033273 36 20 0,000 0,1026928 0,13739239 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,1026928 0,13731719 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,1026928 0,13724207 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,1026928 0,13716703 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1026928 0,13709208 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1026928 0,13701721 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,1026928 0,13694242 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1026928 0,13686771 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,1026928 0,13679308 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1026928 0,13671853 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,1026928 0,13664407 ! peptide secretion GO:0002790 38 20 0,000 0,1026928 0,13656968 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1026928 0,13649538 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,1026928 0,13642116 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,1026928 0,13634701 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1026928 0,13627295 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1026928 0,13619897 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,1026928 0,13612507 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1026928 0,13605125 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,1026928 0,13597751 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,1026928 0,13590385 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,1026928 0,13583027 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1026928 0,13575677 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,1026928 0,13568335 ! regulation of cell killing GO:0031341 46 21 0,000 0,10754256 0,14201431 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10754256 0,14193759 ! hormone secretion GO:0046879 39 21 0,000 0,10754256 0,14186095 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10754256 0,14178439 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10754256 0,14170792 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10754256 0,14163152 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10754256 0,14155521 ! ovarian follicle development GO:0001541 39 21 0,000 0,10754256 0,14147899 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10754256 0,14140284 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,10754256 0,14132678 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10754256 0,14125079 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10754256 0,14117489 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10754256 0,14109907 ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10754256 0,14102334 ! sensory perception of pain GO:0019233 33 21 0,000 0,10754256 0,14094768 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10754256 0,14087211 ! diencephalon development GO:0021536 36 21 0,000 0,10754256 0,14079661 ! collagen fibril organization GO:0030199 62 21 0,000 0,10754256 0,1407212 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,10754256 0,14064587 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10754256 0,14057061 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10754256 0,14049544 ! collagen catabolic process GO:0030574 29 21 0,000 0,10754256 0,14042035 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10754256 0,14034534 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10754256 0,14027041 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10754256 0,14019556 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,10754256 0,14012079 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11236625 0,14632769 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11236625 0,14624973 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11236625 0,14617186 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11236625 0,14609406 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11236625 0,14601635 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11236625 0,14593873 ! microtubule-based transport GO:0010970 59 22 0,000 0,11236625 0,14586118 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11236625 0,14578372 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11236625 0,14570634 ! cellular response to starvation GO:0009267 37 22 0,000 0,11236625 0,14562904 ! vacuolar transport GO:0007034 41 22 0,000 0,11236625 0,14555183 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11236625 0,14547469 ! fucose metabolic process GO:0006004 44 22 0,000 0,11236625 0,14539764 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11236625 0,14532067 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11236625 0,14524378 ! ureteric bud development GO:0001657 50 22 0,000 0,11236625 0,14516697 ! cell aging GO:0007569 48 22 0,000 0,11236625 0,14509025 ! stem cell differentiation GO:0048863 57 22 0,000 0,11236625 0,1450136 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11236625 0,14493703 ! cytolysis GO:0019835 27 22 0,000 0,11236625 0,14486055 ! renal system process GO:0003014 42 22 0,000 0,11236625 0,14478415 ! vasodilation GO:0042311 40 22 0,000 0,11236625 0,14470783 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11236625 0,14463158 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11236625 0,14455542 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11236625 0,14447934 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,11236625 0,14440334 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11236625 0,14432742 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11236625 0,14425157 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11236625 0,14417581 ! sarcomere organization GO:0045214 32 22 0,000 0,11236625 0,14410013 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11236625 0,14402452 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11236625 0,143949 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11236625 0,14387356 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11236625 0,14379819 ! gut development GO:0048565 44 22 0,000 0,11236625 0,1437229 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11236625 0,14364769 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11236625 0,14357256 ! protein stabilization GO:0050821 41 22 0,000 0,11236625 0,14349751 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,117164 0,14954632 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,117164 0,14946822 ! gluconeogenesis GO:0006094 38 23 0,000 0,117164 0,14939021 ! glycerol metabolic process GO:0006071 40 23 0,000 0,117164 0,14931228 ! viral genome replication GO:0019079 44 23 0,000 0,117164 0,14923444 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,117164 0,14915667 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,117164 0,14907898 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,117164 0,14900138 ! regeneration GO:0031099 42 23 0,000 0,117164 0,14892385 ! axis specification GO:0009798 43 23 0,000 0,117164 0,14884641 ! visual behavior GO:0007632 46 23 0,000 0,117164 0,14876905 ! response to ethanol GO:0045471 47 23 0,000 0,117164 0,14869177 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,117164 0,14861456 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,117164 0,14853744 ! peroxisome organization GO:0007031 43 23 0,000 0,117164 0,1484604 ! lysosome organization GO:0007040 47 23 0,000 0,117164 0,14838344 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,117164 0,14830655 ! vesicle targeting GO:0006903 49 23 0,000 0,117164 0,14822975 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,117164 0,14815303 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,117164 0,14807638 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,117164 0,14799982 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,117164 0,14792333 ! DNA modification GO:0006304 36 23 0,000 0,117164 0,14784693 ! fatty acid transport GO:0015908 47 23 0,000 0,117164 0,1477706 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,117164 0,14769435 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,117164 0,14761818 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,117164 0,14754209 ! hormone transport GO:0009914 41 23 0,000 0,117164 0,14746607 ! cell-cell recognition GO:0009988 28 23 0,000 0,117164 0,14739014 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,117164 0,14731428 ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,117164 0,1472385 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12193595 0,15315657 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,12193595 0,15307787 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12193595 0,15299924 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12193595 0,1529207 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12193595 0,15284224 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12193595 0,15276386 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,12193595 0,15268556 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,12193595 0,15260734 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,12193595 0,1525292 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,12193595 0,15245114 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,12193595 0,15237316 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,12193595 0,15229526 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,12193595 0,15221744 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12193595 0,1521397 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,12193595 0,15206204 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,12193595 0,15198445 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,12193595 0,15190695 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12193595 0,15182952 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12193595 0,15175218 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12193595 0,15167491 ! membrane depolarization GO:0051899 45 24 0,000 0,12193595 0,15159772 ! oogenesis GO:0048477 44 24 0,000 0,12193595 0,15152061 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12193595 0,15144358 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,12193595 0,15136663 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12193595 0,15128975 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12193595 0,15121296 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12193595 0,15113624 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12193595 0,1510596 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12193595 0,15098303 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,12193595 0,15090655 ! regulation of amine transport GO:0051952 41 24 0,000 0,12193595 0,15083014 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,12193595 0,15075381 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12668224 0,1565426 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12668224 0,15646346 ! phototransduction GO:0007602 37 25 0,000 0,12668224 0,1563844 ! keratinization GO:0031424 37 25 0,000 0,12668224 0,15630541 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,12668224 0,15622651 ! vacuole organization GO:0007033 49 25 0,000 0,12668224 0,15614769 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12668224 0,15606895 ! receptor metabolic process GO:0043112 53 25 0,000 0,12668224 0,15599028 ! chromosome condensation GO:0030261 48 25 0,000 0,12668224 0,1559117 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12668224 0,15583319 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12668224 0,15575477 ! interaction with host GO:0051701 66 25 0,000 0,12668224 0,15567642 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12668224 0,15559815 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12668224 0,15551996 ! immunoglobulin production GO:0002377 62 25 0,000 0,12668224 0,15544185 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12668224 0,15536381 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12668224 0,15528586 ! liver development GO:0001889 55 25 0,000 0,12668224 0,15520798 ! protein tetramerization GO:0051262 57 25 0,000 0,12668224 0,15513018 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13140301 0,16083044 ! initiation of viral infection GO:0019059 60 26 0,000 0,13140301 0,1607499 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13140301 0,16066945 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13140301 0,16058907 ! molting cycle process GO:0022404 52 26 0,000 0,13140301 0,16050878 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13140301 0,16042856 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,13140301 0,16034843 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,13140301 0,16026838 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13140301 0,1601884 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13140301 0,16010851 ! digestive system process GO:0022600 49 26 0,000 0,13140301 0,16002869 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13140301 0,15994896 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13140301 0,1598693 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13140301 0,15978973 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,13140301 0,15971023 ! neural crest cell development GO:0014032 59 26 0,000 0,13140301 0,15963081 GO:0014033|neural crest cell differentiation, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13140301 0,15955147 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13140301 0,15947221 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13140301 0,15939303 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13140301 0,15931392 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13140301 0,1592349 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13140301 0,15915595 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13140301 0,15907709 ! telomere organization GO:0032200 46 26 0,000 0,13140301 0,1589983 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13140301 0,15891958 ! neural tube closure GO:0001843 58 26 0,000 0,13140301 0,15884095 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,13140301 0,15876239 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13140301 0,15868391 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13140301 0,15860551 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1360984 0,16419179 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1360984 0,16411075 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1360984 0,16402979 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1360984 0,16394891 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1360984 0,1638681 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1360984 0,16378738 ! iron ion transport GO:0006826 65 27 0,000 0,1360984 0,16370674 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1360984 0,16362617 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1360984 0,16354569 ! tube lumen formation GO:0035148 59 27 0,000 0,1360984 0,16346528 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1360984 0,16338495 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,1360984 0,16330471 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,1360984 0,16322454 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1360984 0,16314445 ! response to starvation GO:0042594 47 27 0,000 0,1360984 0,16306443 ! response to toxin GO:0009636 49 27 0,000 0,1360984 0,1629845 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1360984 0,16290464 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,1360984 0,16282487 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1360984 0,16274517 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1360984 0,16266555 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,14076853 0,16816504 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,14076853 0,16808285 ! vesicle docking GO:0048278 55 28 0,000 0,14076853 0,16800074 ! circadian rhythm GO:0007623 56 28 0,000 0,14076853 0,16791871 ! dendrite development GO:0016358 67 28 0,000 0,14076853 0,16783676 ! fat cell differentiation GO:0045444 57 28 0,000 0,14076853 0,16775488 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,14076853 0,16767309 ! sperm motility GO:0030317 37 28 0,000 0,14076853 0,16759138 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,14076853 0,16750975 ! base-excision repair GO:0006284 41 28 0,000 0,14076853 0,1674282 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,14076853 0,16734672 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,14076853 0,16726533 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,14076853 0,16718401 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,14076853 0,16710278 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,14076853 0,16702162 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,14076853 0,16694054 ! glutathione metabolic process GO:0006749 42 28 0,000 0,14076853 0,16685954 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,14076853 0,16677862 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,14076853 0,16669778 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,14076853 0,16661701 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,14541355 0,17203162 ! translational initiation GO:0006413 66 29 0,000 0,14541355 0,17194835 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14541355 0,17186516 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14541355 0,17178206 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,14541355 0,17169903 ! autophagy GO:0006914 47 29 0,000 0,14541355 0,17161608 ! primary neural tube formation GO:0014020 61 29 0,000 0,14541355 0,17153322 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14541355 0,17145043 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14541355 0,17136772 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,14541355 0,1712851 ! somitogenesis GO:0001756 52 29 0,000 0,14541355 0,17120255 ! synaptogenesis GO:0007416 46 29 0,000 0,14541355 0,17112008 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14541355 0,17103769 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14541355 0,17095539 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,14541355 0,17087316 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,15003358 0,17621733 ! phenol metabolic process GO:0018958 56 30 0,000 0,15003358 0,17613265 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,15003358 0,17604805 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,15003358 0,17596353 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,15003358 0,1758791 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,15003358 0,17579474 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,15003358 0,17571047 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,15003358 0,17562628 ! acute-phase response GO:0006953 50 30 0,000 0,15003358 0,17554217 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,15003358 0,17545813 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,15003358 0,17537418 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,15003358 0,17529031 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,15003358 0,17520652 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,15003358 0,17512281 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,15003358 0,17503918 ! phospholipid transport GO:0015914 65 30 0,000 0,15003358 0,17495563 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,15003358 0,17487216 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,15003358 0,17478877 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,15003358 0,17470545 ! tissue homeostasis GO:0001894 50 30 0,000 0,15003358 0,17462222 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,15003358 0,17453907 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15462877 0,17979919 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15462877 0,17971365 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15462877 0,17962819 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15462877 0,17954282 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15462877 0,17945752 ! ovulation cycle process GO:0022602 55 31 0,000 0,15462877 0,17937231 ! peptide transport GO:0015833 60 31 0,000 0,15462877 0,17928718 ! male gonad development GO:0008584 56 31 0,000 0,15462877 0,17920213 ! detection of light stimulus GO:0009583 44 31 0,000 0,15462877 0,17911716 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,15462877 0,17903227 ! natural killer cell activation GO:0030101 50 31 0,000 0,15462877 0,17894746 ! eye morphogenesis GO:0048592 65 31 0,000 0,15462877 0,17886273 ! response to heat GO:0009408 54 31 0,000 0,15462877 0,17877808 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15462877 0,17869351 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15919925 0,1838883 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15919925 0,1838014 ! collagen metabolic process GO:0032963 49 32 0,000 0,15919925 0,18371458 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,15919925 0,18362784 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15919925 0,18354118 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15919925 0,1834546 ! metanephros development GO:0001656 81 32 0,000 0,15919925 0,18336811 ! mesoderm formation GO:0001707 73 32 0,000 0,15919925 0,1832817 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15919925 0,18319536 ! ovulation cycle GO:0042698 57 32 0,000 0,15919925 0,18310911 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15919925 0,18302295 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15919925 0,18293686 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15919925 0,18285085 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,15919925 0,18276492 ! regulation of pH GO:0006885 56 33 0,000 0,16374514 0,18789543 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,16374514 0,18780722 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16374514 0,18771909 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16374514 0,18763104 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16374514 0,18754307 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,16374514 0,18745519 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,16374514 0,18736739 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16374514 0,18727967 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16374514 0,18719203 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,16374514 0,18710448 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,16374514 0,18701701 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16826658 0,19209124 ! post-embryonic development GO:0009791 76 34 0,000 0,16826658 0,19200152 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16826658 0,19191189 ! cholesterol transport GO:0030301 62 34 0,000 0,16826658 0,19182233 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16826658 0,19173286 ! spliceosome assembly GO:0000245 75 34 0,000 0,16826658 0,19164348 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16826658 0,19155417 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16826658 0,19146495 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16826658 0,19137582 ! cell fate specification GO:0001708 56 34 0,000 0,16826658 0,19128677 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16826658 0,19119779 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,1727637 0,19621652 ! negative regulation of secretion GO:0051048 68 35 0,000 0,1727637 0,19612534 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,1727637 0,19603424 ! membrane docking GO:0022406 69 35 0,000 0,1727637 0,19594323 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,1727637 0,19585231 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,1727637 0,19576147 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,1727637 0,19567071 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,1727637 0,19558004 ! ceramide metabolic process GO:0006672 72 35 0,000 0,1727637 0,19548945 ! sterol transport GO:0015918 63 35 0,000 0,1727637 0,19539895 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,1727637 0,19530853 ! vesicle localization GO:0051648 70 35 0,000 0,1727637 0,19521819 ! regulation of muscle development GO:0048634 82 36 0,000 0,17723664 0,20017989 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17723664 0,20008739 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17723664 0,19999497 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17723664 0,19990263 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17723664 0,19981038 ! regulation of proteolysis GO:0030162 77 36 0,000 0,17723664 0,19971822 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,17723664 0,19962614 ! cytokine production GO:0001816 68 36 0,000 0,17723664 0,19953415 ! embryonic organ development GO:0048568 67 36 0,000 0,17723664 0,19944224 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17723664 0,19935042 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17723664 0,19925868 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,18168551 0,20416637 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,18168551 0,20407251 ! odontogenesis GO:0042476 74 37 0,000 0,18168551 0,20397872 ! tissue remodeling GO:0048771 78 37 0,000 0,18168551 0,20388502 ! female gonad development GO:0008585 71 37 0,000 0,18168551 0,20379141 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,18168551 0,20369789 ! organic anion transport GO:0015711 82 38 0,000 0,18611045 0,20856322 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18611045 0,2084676 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,18611045 0,20837206 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18611045 0,20827661 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18611045 0,20818124 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18611045 0,20808596 ! spermatid development GO:0007286 69 38 0,000 0,18611045 0,20799077 ! glycogen metabolic process GO:0005977 63 38 0,000 0,18611045 0,20789567 ! pigment metabolic process GO:0042440 87 38 0,000 0,18611045 0,20780065 ! neural tube formation GO:0001841 79 38 0,000 0,18611045 0,20770572 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,19051159 0,21252046 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,19051159 0,21242346 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,19051159 0,21232656 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,19051159 0,21222973 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,19051159 0,212133 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,19051159 0,21203636 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,19051159 0,2119398 ! glucan metabolic process GO:0044042 64 39 0,000 0,19051159 0,21184334 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,19488905 0,21661235 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,19488905 0,21651385 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,19488905 0,21641543 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,19488905 0,2163171 ! mismatch repair GO:0006298 58 40 0,000 0,19488905 0,21621887 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,19488905 0,21612072 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,19488905 0,21602266 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19924296 0,22074855 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19924296 0,22064848 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19924296 0,22054851 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,19924296 0,22044862 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,19924296 0,22034883 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19924296 0,22024912 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19924296 0,2201495 ! feeding behavior GO:0007631 69 41 0,000 0,19924296 0,22004998 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,19924296 0,21995054 ! mesenchymal cell development GO:0014031 94 41 0,000 0,19924296 0,2198512 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,19924296 0,21975194 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19924296 0,21965278 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,19924296 0,2195537 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,19924296 0,21945471 ! RNA modification GO:0009451 64 41 0,000 0,19924296 0,21935582 ! organic ether metabolic process GO:0018904 59 42 0,000 0,20357345 0,2240225 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,20357345 0,22392163 ! T cell differentiation GO:0030217 93 42 0,000 0,20357345 0,22382086 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,20357345 0,22372017 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,20357345 0,22361958 ! regulation of protein secretion GO:0050708 77 42 0,000 0,20357345 0,22351907 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,20357345 0,22341866 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,20357345 0,22331834 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,20788064 0,22794094 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,20788064 0,22783868 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,20788064 0,22773651 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,20788064 0,22763443 ! regulation of tube size GO:0035150 76 43 0,000 0,20788064 0,22753244 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,20788064 0,22743055 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,20788064 0,22732874 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,20788064 0,22722703 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,20788064 0,22712541 ! segmentation GO:0035282 78 43 0,000 0,20788064 0,22702387 ! ion transmembrane transport GO:0034220 79 43 0,000 0,20788064 0,22692243 ! neuron migration GO:0001764 85 43 0,000 0,20788064 0,22682108 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,21216466 0,23139208 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,21216466 0,23128883 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,21216466 0,23118567 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,21216466 0,2310826 ! striated muscle contraction GO:0006941 85 44 0,000 0,21216466 0,23097962 ! phagocytosis GO:0006909 105 44 0,000 0,21216466 0,23087673 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,21216466 0,23077394 ! double-strand break repair GO:0006302 85 44 0,000 0,21216466 0,23067123 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,21642563 0,2351992 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,21642563 0,23509462 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,21642563 0,23499014 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,21642563 0,23488574 ! B cell differentiation GO:0030183 124 45 0,000 0,21642563 0,23478144 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,21642563 0,23467723 ! female gamete generation GO:0007292 71 45 0,000 0,21642563 0,23457312 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,21642563 0,2344691 ! polyol metabolic process GO:0019751 77 45 0,000 0,21642563 0,23436516 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,22066367 0,23884863 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,22066367 0,23874285 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,22066367 0,23863716 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,22066367 0,23853157 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,22066367 0,23842607 ! neural tube development GO:0021915 91 47 0,000 0,22487891 0,2428732 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,22487891 0,24276588 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,22907147 0,24718268 ! mitochondrial transport GO:0006839 94 48 0,000 0,22907147 0,24707355 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,22907147 0,24696452 ! endosome transport GO:0016197 127 48 0,000 0,22907147 0,24685558 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,22907147 0,24674674 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,22907147 0,24663799 ! male sex differentiation GO:0046661 93 48 0,000 0,22907147 0,24652934 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,22907147 0,24642078 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,22907147 0,24631232 ! methylation GO:0032259 97 48 0,000 0,22907147 0,24620396 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,23324147 0,2505756 ! JNK cascade GO:0007254 106 49 0,000 0,23324147 0,25046545 ! protein homooligomerization GO:0051260 84 49 0,000 0,23324147 0,25035541 ! regulation of ion transport GO:0043269 86 50 0,000 0,23738903 0,25469539 ! endocrine system development GO:0035270 109 50 0,000 0,23738903 0,25458358 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23738903 0,25447187 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,23738903 0,25436026 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,23738903 0,25424875 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,23738903 0,25413733 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,24151427 0,25844037 ! viral infectious cycle GO:0019058 104 51 0,000 0,24151427 0,25832721 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,24151427 0,25821416 ! peptide metabolic process GO:0006518 80 51 0,000 0,24151427 0,25810121 ! response to temperature stimulus GO:0009266 84 51 0,000 0,24151427 0,25798835 ! positive regulation of binding GO:0051099 88 52 0,000 0,24561731 0,2622566 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,24561731 0,26214202 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,24561731 0,26202755 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,24561731 0,26191318 ! excretion GO:0007588 87 52 0,000 0,24561731 0,2617989 ! histone modification GO:0016570 104 52 0,000 0,24561731 0,26168473 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,24561731 0,26157066 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,24561731 0,26145668 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,24561731 0,26134281 ! amino acid activation GO:0043038 98 52 0,000 0,24561731 0,26122903 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24969827 0,26545382 ! positive regulation of growth GO:0045927 96 53 0,000 0,24969827 0,26533835 ! inner ear development GO:0048839 89 53 0,000 0,24969827 0,26522299 ! chromatin remodeling GO:0006338 122 53 0,000 0,24969827 0,26510773 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,24969827 0,26499256 ! regulation of translational initiation GO:0006446 87 54 0,000 0,25375727 0,26918324 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,25375727 0,26906641 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,25375727 0,26894968 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,25375727 0,26883305 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,25375727 0,26871652 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,25375727 0,26860009 ! regulation of cell shape GO:0008360 142 54 0,000 0,25375727 0,26848376 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,25375727 0,26836754 ! RNA catabolic process GO:0006401 103 55 0,000 0,25779442 0,27251916 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,25779442 0,27240129 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,25779442 0,27228352 ! cell recognition GO:0008037 98 55 0,000 0,25779442 0,27216585 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,25779442 0,27204829 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,25779442 0,27193082 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,26180985 0,27604725 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,26180985 0,27592816 ! RNA elongation GO:0006354 90 56 0,000 0,26180985 0,27580917 ! chloride transport GO:0006821 102 57 0,000 0,26580367 0,27989584 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,26580367 0,27977525 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,26580367 0,27965476 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,26977599 0,2837119 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,26977599 0,28358982 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26977599 0,28346784 ! gastrulation GO:0007369 122 58 0,000 0,26977599 0,28334597 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26977599 0,28322421 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,26977599 0,28310255 ! nuclear export GO:0051168 110 59 0,000 0,27372692 0,28712532 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,2776566 0,29112235 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,2776566 0,29099745 ! adult behavior GO:0030534 104 60 0,000 0,2776566 0,29087267 ! kidney development GO:0001822 133 60 0,000 0,2776566 0,29074799 ! positive regulation of secretion GO:0051047 110 61 0,000 0,28156512 0,29471447 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,28156512 0,29458826 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,28156512 0,29446215 ! camera-type eye development GO:0043010 126 61 0,000 0,28156512 0,29433615 ! proton transport GO:0015992 117 61 0,000 0,28156512 0,29421026 ! viral reproductive process GO:0022415 132 62 0,000 0,2854526 0,2981448 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,2854526 0,29801739 ! tRNA processing GO:0008033 102 62 0,000 0,2854526 0,29789009 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,28931915 0,3017962 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,28931915 0,30166739 ! hydrogen transport GO:0006818 121 64 0,000 0,29316489 0,30554686 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,29316489 0,30541656 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,29698993 0,30926957 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,29698993 0,30913779 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,29698993 0,30900613 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,29698993 0,30887459 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,30079438 0,31269816 ! gonad development GO:0008406 115 66 0,000 0,30079438 0,31256515 ! activation of MAPK activity GO:0000187 124 67 0,000 0,30457834 0,31636262 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,30457834 0,31622817 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,30457834 0,31609384 ! secondary metabolic process GO:0019748 125 67 0,000 0,30457834 0,31595961 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,30834193 0,31972807 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,30834193 0,31959242 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30834193 0,31945689 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,30834193 0,31932147 ! viral reproduction GO:0016032 142 68 0,000 0,30834193 0,31918616 ! regulation of lipase activity GO:0060191 137 68 0,000 0,30834193 0,31905097 ! adaptive immune response GO:0002250 126 68 0,000 0,30834193 0,3189159 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,30834193 0,31878093 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,31208526 0,32251451 ! lung development GO:0030324 165 69 0,000 0,31208526 0,32237814 ! urogenital system development GO:0001655 149 69 0,000 0,31208526 0,32224188 ! cell redox homeostasis GO:0045454 114 70 0,000 0,31580844 0,32594846 ! germ cell development GO:0007281 133 70 0,000 0,31580844 0,32581082 ! activation of immune response GO:0002253 120 70 0,000 0,31580844 0,32567329 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,31951157 0,32935306 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,31951157 0,32921415 ! respiratory tube development GO:0030323 171 72 0,000 0,32319476 0,3328688 ! B cell activation GO:0042113 179 72 0,000 0,32319476 0,33272852 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,32319476 0,33258837 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,32319476 0,33244833 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,32319476 0,33230841 ! humoral immune response GO:0006959 115 73 0,000 0,32685811 0,33593369 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,32685811 0,33579242 ! regulation of immune effector process GO:0002697 156 73 0,000 0,32685811 0,33565127 ! acute inflammatory response GO:0002526 118 74 0,000 0,33050174 0,33925032 ! amino acid transport GO:0006865 148 74 0,000 0,33050174 0,33910784 ! respiratory system development GO:0060541 175 74 0,000 0,33050174 0,33896548 ! transition metal ion transport GO:0000041 143 75 0,000 0,33412576 0,34253849 ! reproductive structure development GO:0048608 131 75 0,000 0,33412576 0,34239481 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,33412576 0,34225125 ! eye development GO:0001654 155 75 0,000 0,33412576 0,3421078 ! rhythmic process GO:0048511 142 75 0,000 0,33412576 0,34196448 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,33773025 0,3455088 ! regulation of blood pressure GO:0008217 134 76 0,000 0,33773025 0,34536417 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,33773025 0,34521967 ! neurotransmitter transport GO:0006836 142 77 0,000 0,34131534 0,34873834 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,34131534 0,34859254 ! regulation of catabolic process GO:0009894 173 77 0,000 0,34131534 0,34844687 ! antigen processing and presentation GO:0019882 117 78 0,000 0,34488111 0,35194008 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,34842769 0,35541079 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,34842769 0,35526246 ! protein oligomerization GO:0051259 149 79 0,000 0,34842769 0,35511424 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,35195516 0,35855983 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,35195516 0,35841036 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,35546364 0,36183236 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,36242401 0,36876378 ! exocytosis GO:0006887 153 83 0,000 0,36242401 0,36861026 ! response to drug GO:0042493 149 83 0,000 0,36242401 0,36845686 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,36242401 0,3683036 ! inorganic anion transport GO:0015698 156 83 0,000 0,36242401 0,36815046 ! T cell activation GO:0042110 189 84 0,000 0,3658761 0,37150262 ! response to nutrient GO:0007584 135 84 0,000 0,3658761 0,37134828 ! digestion GO:0007586 130 84 0,000 0,3658761 0,37119406 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,36930959 0,37452193 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,36930959 0,37436653 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,37272459 0,37767158 ! regulation of lyase activity GO:0051339 169 86 0,000 0,37272459 0,377515 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,3761212 0,38079739 ! nucleosome assembly GO:0006334 126 87 0,000 0,3761212 0,38063964 ! sensory perception of smell GO:0007608 117 88 0,000 0,37949951 0,38389951 ! chromatin assembly GO:0031497 128 88 0,000 0,37949951 0,38374061 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,38285962 0,3869781 ! tube morphogenesis GO:0035239 194 89 0,000 0,38285962 0,38681805 ! cellular defense response GO:0006968 123 89 0,000 0,38285962 0,38665815 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,38620163 0,38987214 ! response to unfolded protein GO:0006986 139 90 0,000 0,38620163 0,38971111 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,38952564 0,39290303 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,38952564 0,39274087 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,39283173 0,39591086 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,39612002 0,39906029 ! amine transport GO:0015837 181 93 0,000 0,39612002 0,3988958 ! vitamin metabolic process GO:0006766 153 93 0,000 0,39612002 0,39873144 ! sterol metabolic process GO:0016125 166 94 0,000 0,39939059 0,40185799 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,39939059 0,40169255 ! nucleosome organization GO:0034728 143 95 0,000 0,40264354 0,4047976 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,40264354 0,40463108 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,40264354 0,40446471 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,40264354 0,40429846 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,40264354 0,40413236 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,40264354 0,40396639 ! sex differentiation GO:0007548 171 96 0,000 0,40587896 0,40704528 ! response to protein stimulus GO:0051789 158 96 0,000 0,40587896 0,40687825 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,40909695 0,40993595 ! leukocyte differentiation GO:0002521 232 98 0,000 0,4122976 0,41297377 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,4122976 0,41280452 ! mRNA transport GO:0051028 185 100 0,000 0,41864724 0,41899026 ! positive regulation of immune response GO:0050778 175 100 0,000 0,41864724 0,41881868 ! hormone metabolic process GO:0042445 171 100 0,000 0,41864724 0,41864724