pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6836-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! L-serine biosynthetic process GO:0006564 6 5 2,000 5,133E-08 1,235E-04 ! L-serine metabolic process GO:0006563 18 10 2,000 6,121E-07 7,364E-04 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 1,453E-06 1,166E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 7,739E-06 4,655E-03 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 1,82E-05 8,76E-03 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 2,234E-05 8,958E-03 ! regulation of microtubule-based process GO:0032886 78 35 2,000 3,236E-05 0,01112406 ! male meiosis GO:0007140 7 6 1,000 4,537E-05 0,01364599 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,537E-05 0,01212977 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 4,537E-05 0,01091679 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,345E-05 0,01387842 ! rRNA modification GO:0000154 14 7 1,000 6,345E-05 0,01272189 ! coenzyme A metabolic process GO:0015936 12 7 1,000 6,345E-05 0,01174328 ! ER overload response GO:0006983 12 8 1,000 8,451E-05 0,01452289 ! ATP catabolic process GO:0006200 11 8 1,000 8,451E-05 0,0135547 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 1,009E-04 0,01518021 ! RNA methylation GO:0001510 15 9 1,000 1,085E-04 0,01535983 ! microtubule bundle formation GO:0001578 21 9 1,000 1,085E-04 0,01450651 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 1,085E-04 0,01374301 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,085E-04 0,01305586 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,355E-04 0,01552515 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,355E-04 0,01481946 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,355E-04 0,01417514 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,355E-04 0,01358451 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 1,56E-04 0,0150162 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 1,654E-04 0,01530883 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,983E-04 0,01767025 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 2,276E-04 0,01956162 ! ribonucleotide catabolic process GO:0009261 20 13 1,000 2,341E-04 0,01942088 ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,341E-04 0,01877352 ! negative regulation of kinase activity GO:0033673 131 68 2,000 2,379E-04 0,0184611 ! negative regulation of transferase activity GO:0051348 140 72 2,000 2,817E-04 0,02117748 ! phospholipid catabolic process GO:0009395 22 15 1,000 3,144E-04 0,02292281 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 3,144E-04 0,02224861 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,589E-04 0,02467265 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,589E-04 0,0239873 GO:0031114|regulation of microtubule depolymerization, ! intermediate filament-based process GO:0045103 32 16 1,000 3,589E-04 0,023339 ! axon cargo transport GO:0008088 43 16 1,000 3,589E-04 0,02272481 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,063E-04 0,02506612 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 4,566E-04 0,02746342 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,566E-04 0,02679358 ! amine biosynthetic process GO:0009309 138 86 2,000 4,75E-04 0,0272107 ! purine nucleotide catabolic process GO:0006195 29 19 1,000 5,097E-04 0,02852076 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,657E-04 0,03093462 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,657E-04 0,03024718 ! negative regulation of translation GO:0017148 29 20 1,000 5,657E-04 0,02958963 ! microtubule-based transport GO:0010970 54 22 1,000 6,862E-04 0,03513006 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 6,862E-04 0,03439818 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,862E-04 0,03369618 ! cell cycle arrest GO:0007050 213 100 2,000 7,376E-04 0,03549334 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 7,508E-04 0,03541813 GO:0042278|purine nucleoside metabolic process, ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,181E-04 0,03785225 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 8,181E-04 0,03713805 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 8,882E-04 0,03957529 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 8,882E-04 0,03885574 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 9,612E-04 0,04129549 GO:0045936|negative regulation of phosphate metabolic process, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 9,612E-04 0,04057101 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,037E-03 0,04301275 ! dendrite development GO:0016358 59 28 1,000 1,115E-03 0,04548505 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,115E-03 0,04472697 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 1,197E-03 0,04719935 ! regulation of B cell activation GO:0050864 50 30 1,000 1,281E-03 0,04969908 ! glycogen metabolic process GO:0005977 61 37 1,000 1,945E-03 0,07429554 ! nucleotide catabolic process GO:0009166 61 38 1,000 2,051E-03 0,07711091 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 2,051E-03 0,07592459 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 2,051E-03 0,07477422 GO:0006073|cellular glucan metabolic process, ! RNA modification GO:0009451 57 39 1,000 2,16E-03 0,07755242 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 2,271E-03 0,08034321 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 2,501E-03 0,08720488 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 2,501E-03 0,08595909 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 2,501E-03 0,0847484 ! energy reserve metabolic process GO:0006112 74 43 1,000 2,62E-03 0,0875495 ! biopolymer methylation GO:0043414 84 44 1,000 2,742E-03 0,09036047 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 2,866E-03 0,0931806 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 2,993E-03 0,09600923 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 2,993E-03 0,09474595 ! positive regulation of protein transport GO:0051222 72 46 1,000 2,993E-03 0,09351548 ! methylation GO:0032259 90 47 1,000 3,122E-03 0,09631123 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 3,254E-03 0,0991151 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 3,389E-03 0,10192652 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 3,666E-03 0,10889786 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! amino acid activation GO:0043038 92 52 1,000 3,809E-03 0,11174705 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! response to UV GO:0009411 104 53 1,000 3,953E-03 0,11460137 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 4,101E-03 0,11746037 ! heterocycle catabolic process GO:0046700 85 54 1,000 4,101E-03 0,11607849 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 4,251E-03 0,11892453 ! nuclear export GO:0051168 97 55 1,000 4,251E-03 0,11755758 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 4,558E-03 0,12462886 ! regulation of intracellular transport GO:0032386 101 57 1,000 4,558E-03 0,12322854 ! nucleoside metabolic process GO:0009116 81 60 1,000 5,038E-03 0,13469054 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 5,888E-03 0,15566559 ! negative regulation of cell growth GO:0030308 132 67 1,000 6,244E-03 0,16330435 ! negative regulation of cell size GO:0045792 134 69 1,000 6,611E-03 0,17102842 ! meiosis GO:0007126 121 74 1,000 7,569E-03 0,19372557 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 163 75 1,000 7,767E-03 0,19671758 ! meiotic cell cycle GO:0051321 122 75 1,000 7,767E-03 0,19466844 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 8,172E-03 0,20269065 ! negative regulation of organelle organization GO:0010639 161 78 1,000 8,377E-03 0,20567151 ! activation of protein kinase activity GO:0032147 147 79 1,000 8,585E-03 0,20864846 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 8,769E-03 0,21097451 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 8,769E-03 0,20888565 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,769E-03 0,20683775 ! positive regulation of helicase activity GO:0051096 11 5 0,000 8,769E-03 0,20482962 ! neuron fate determination GO:0048664 7 5 0,000 8,769E-03 0,2028601 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,769E-03 0,2009281 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 8,769E-03 0,19903256 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 8,769E-03 0,19717244 ! polyol transport GO:0015791 12 5 0,000 8,769E-03 0,19534677 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 8,769E-03 0,19355459 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,769E-03 0,19179501 ! response to superoxide GO:0000303 10 5 0,000 8,769E-03 0,19006712 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,769E-03 0,1883701 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 8,769E-03 0,1867031 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 8,769E-03 0,18506536 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,769E-03 0,18345609 ! female meiosis GO:0007143 7 5 0,000 8,769E-03 0,18187458 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,769E-03 0,18032009 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,769E-03 0,17879196 ! cobalt ion transport GO:0006824 11 5 0,000 8,769E-03 0,1772895 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 8,769E-03 0,17581209 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 8,769E-03 0,1743591 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 8,769E-03 0,17292993 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,769E-03 0,17152399 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,769E-03 0,17014073 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 8,769E-03 0,16877961 ! embryonic camera-type eye development GO:0031076 10 5 0,000 8,769E-03 0,16744009 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,769E-03 0,16612166 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 8,769E-03 0,16482383 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 8,769E-03 0,16354613 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,769E-03 0,16228808 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,769E-03 0,16104924 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,769E-03 0,15982917 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 8,769E-03 0,15862745 ! negative chemotaxis GO:0050919 14 5 0,000 8,769E-03 0,15744366 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,769E-03 0,15627741 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,769E-03 0,15512832 ! sensory perception of bitter taste GO:0050913 7 5 0,000 8,769E-03 0,15399599 ! behavioral response to pain GO:0048266 9 5 0,000 8,769E-03 0,15288008 ! clathrin coat assembly GO:0048268 14 5 0,000 8,769E-03 0,15178022 ! Notch receptor processing GO:0007220 8 5 0,000 8,769E-03 0,15069608 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,769E-03 0,14962731 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,769E-03 0,1485736 ! micturition GO:0060073 9 5 0,000 8,769E-03 0,14753462 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,769E-03 0,14651008 ! copulation GO:0007620 9 5 0,000 8,769E-03 0,14549966 ! glial cell fate commitment GO:0021781 13 5 0,000 8,769E-03 0,14450309 ! protein maturation by protein folding GO:0022417 13 5 0,000 8,769E-03 0,14352007 ! spermidine metabolic process GO:0008216 7 5 0,000 8,769E-03 0,14255034 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,769E-03 0,14159363 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,769E-03 0,14064967 ! apoptotic cell clearance GO:0043277 20 5 0,000 8,769E-03 0,13971822 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,769E-03 0,13879902 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,769E-03 0,13789184 ! grooming behavior GO:0007625 6 5 0,000 8,769E-03 0,13699643 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,769E-03 0,13611259 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 8,769E-03 0,13524007 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,769E-03 0,13437867 ! response to protozoan GO:0001562 10 5 0,000 8,769E-03 0,13352817 ! positive regulation of glycolysis GO:0045821 14 5 0,000 8,769E-03 0,13268837 ! lymph vessel development GO:0001945 10 5 0,000 8,769E-03 0,13185907 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 8,769E-03 0,13104007 ! endochondral ossification GO:0001958 16 5 0,000 8,769E-03 0,13023118 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,769E-03 0,12943221 ! parathyroid gland development GO:0060017 13 5 0,000 8,769E-03 0,12864299 ! anagen GO:0042640 6 5 0,000 8,769E-03 0,12786334 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,769E-03 0,12709308 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,769E-03 0,12633204 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 8,769E-03 0,12558006 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 8,769E-03 0,12483699 ! dorsal spinal cord development GO:0021516 7 5 0,000 8,769E-03 0,12410265 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 8,769E-03 0,12337691 ! sphingoid catabolic process GO:0046521 6 5 0,000 8,769E-03 0,1226596 ! skeletal myofibril assembly GO:0014866 10 5 0,000 8,769E-03 0,12195058 ! smooth muscle tissue development GO:0048745 28 5 0,000 8,769E-03 0,12124972 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,769E-03 0,12055686 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,769E-03 0,11987188 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,769E-03 0,11919464 ! cardiac muscle fiber development GO:0048739 10 5 0,000 8,769E-03 0,118525 ! transepithelial chloride transport GO:0030321 9 5 0,000 8,769E-03 0,11786285 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,769E-03 0,11720806 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 8,769E-03 0,1165605 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 8,769E-03 0,11592006 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,769E-03 0,11528662 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,769E-03 0,11466006 ! histidine catabolic process GO:0006548 6 5 0,000 8,769E-03 0,11404027 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 8,769E-03 0,11342716 ! microvillus organization GO:0032528 7 5 0,000 8,769E-03 0,11282059 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 8,769E-03 0,11222048 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,769E-03 0,11162672 ! tryptophan metabolic process GO:0006568 9 5 0,000 8,769E-03 0,11103922 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 8,769E-03 0,11045786 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,769E-03 0,10988256 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 8,769E-03 0,10931322 ! polyol catabolic process GO:0046174 7 5 0,000 8,769E-03 0,10874975 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,769E-03 0,10819206 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,769E-03 0,10764006 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,769E-03 0,10709366 ! muscle cell migration GO:0014812 8 5 0,000 8,769E-03 0,10655278 ! mitochondrial fission GO:0000266 8 5 0,000 8,769E-03 0,10601734 ! sister chromatid cohesion GO:0007062 12 5 0,000 8,769E-03 0,10548725 ! mRNA transcription GO:0009299 9 5 0,000 8,769E-03 0,10496244 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 8,769E-03 0,10444283 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 8,769E-03 0,10392833 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 8,769E-03 0,10341888 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,769E-03 0,10291439 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,769E-03 0,10241481 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,769E-03 0,10192005 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,769E-03 0,10143005 ! response to food GO:0032094 6 5 0,000 8,769E-03 0,10094474 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,769E-03 0,10046405 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,769E-03 0,09998792 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 8,769E-03 0,09951628 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,769E-03 0,09904907 ! paraxial mesoderm development GO:0048339 14 5 0,000 8,769E-03 0,09858622 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 8,769E-03 0,09812768 ! forebrain neuron development GO:0021884 13 5 0,000 8,769E-03 0,09767338 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,769E-03 0,09722328 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 8,769E-03 0,0967773 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,769E-03 0,09633539 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,769E-03 0,0958975 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,769E-03 0,09546358 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 8,769E-03 0,09503356 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,769E-03 0,0946074 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 8,769E-03 0,09418505 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 8,769E-03 0,09376645 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,769E-03 0,09335155 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 8,769E-03 0,09294031 ! basic amino acid transport GO:0015802 11 5 0,000 8,769E-03 0,09253268 ! cellular glucose homeostasis GO:0001678 5 5 0,000 8,769E-03 0,09212861 ! early endosome to late endosome transport GO:0045022 12 5 0,000 8,769E-03 0,09172805 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,769E-03 0,09133096 ! depyrimidination GO:0045008 10 5 0,000 8,769E-03 0,09093729 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,769E-03 0,090547 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,769E-03 0,09016005 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,769E-03 0,08977639 ! zinc ion homeostasis GO:0055069 8 5 0,000 8,769E-03 0,08939598 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 8,769E-03 0,08901878 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 8,769E-03 0,08864475 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,769E-03 0,08827385 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,769E-03 0,08790605 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,769E-03 0,08754129 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 8,769E-03 0,08717955 ! peptidyl-arginine modification GO:0018195 9 5 0,000 8,769E-03 0,08682079 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,769E-03 0,08646496 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,769E-03 0,08611204 ! response to arsenic GO:0046685 10 5 0,000 8,769E-03 0,085762 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 8,769E-03 0,08541478 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 8,769E-03 0,08507037 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 8,769E-03 0,08472872 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 8,769E-03 0,0843898 ! response to cadmium ion GO:0046686 7 5 0,000 8,769E-03 0,08405359 ! bile acid biosynthetic process GO:0006699 6 5 0,000 8,769E-03 0,08372004 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 8,769E-03 0,08338913 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,769E-03 0,08306083 ! decidualization GO:0046697 11 5 0,000 8,769E-03 0,0827351 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 8,769E-03 0,08241192 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 8,769E-03 0,08209125 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,769E-03 0,08177307 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,769E-03 0,08145734 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 8,769E-03 0,08114404 ! base conversion or substitution editing GO:0016553 5 5 0,000 8,769E-03 0,08083315 ! neural tube patterning GO:0021532 7 5 0,000 8,769E-03 0,08052462 ! embryonic cleavage GO:0040016 6 5 0,000 8,769E-03 0,08021844 ! peroxisome fission GO:0016559 5 5 0,000 8,769E-03 0,07991459 ! histone demethylation GO:0016577 10 5 0,000 8,769E-03 0,07961302 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 8,769E-03 0,07931373 ! mitotic recombination GO:0006312 9 5 0,000 8,769E-03 0,07901667 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,769E-03 0,07872183 ! metaphase plate congression GO:0051310 7 5 0,000 8,769E-03 0,07842919 ! regulation of sterol transport GO:0032371 7 5 0,000 8,769E-03 0,07813871 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,769E-03 0,07785037 ! enteric nervous system development GO:0048484 8 5 0,000 8,769E-03 0,07756416 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 8,769E-03 0,07728004 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 8,769E-03 0,076998 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 8,769E-03 0,076718 ! muscle cell proliferation GO:0033002 11 5 0,000 8,769E-03 0,07644004 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,769E-03 0,07616408 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 8,769E-03 0,07589011 ! plasminogen activation GO:0031639 5 5 0,000 8,769E-03 0,0756181 ! B cell homeostasis GO:0001782 13 5 0,000 8,769E-03 0,07534804 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 8,769E-03 0,0750799 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,769E-03 0,07481366 ! metaphase GO:0051323 8 5 0,000 8,769E-03 0,0745493 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 8,769E-03 0,0742868 ! cellular response to nutrient GO:0031670 8 5 0,000 8,769E-03 0,07402614 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,769E-03 0,07376731 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,769E-03 0,07351028 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,769E-03 0,07325504 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 8,769E-03 0,07300156 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 8,769E-03 0,07274983 ! response to redox state GO:0051775 5 5 0,000 8,769E-03 0,07249983 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 8,769E-03 0,07225154 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 8,769E-03 0,07200495 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,769E-03 0,07176004 ! regulation of telomerase activity GO:0051972 6 5 0,000 8,769E-03 0,07151678 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,769E-03 0,07127517 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 8,769E-03 0,07103519 ! porphyrin catabolic process GO:0006787 12 5 0,000 8,769E-03 0,07079681 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 8,769E-03 0,07056004 ! striatum development GO:0021756 9 5 0,000 8,769E-03 0,07032484 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 8,769E-03 0,0700912 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 8,769E-03 0,06985911 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,769E-03 0,06962855 ! glial cell migration GO:0008347 11 5 0,000 8,769E-03 0,06939951 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,769E-03 0,06917197 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 8,769E-03 0,06894592 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,769E-03 0,06872134 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,769E-03 0,06849822 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,769E-03 0,06827654 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,769E-03 0,06805629 ! neuroprotection GO:0043526 6 5 0,000 8,769E-03 0,06783746 ! neural plate development GO:0001840 8 5 0,000 8,769E-03 0,06762003 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,769E-03 0,067404 ! regulation of sensory perception GO:0051931 7 5 0,000 8,769E-03 0,06718933 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,769E-03 0,06697603 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,769E-03 0,06676408 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 8,769E-03 0,06655347 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 8,769E-03 0,06634419 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,769E-03 0,06613621 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,769E-03 0,06592953 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,769E-03 0,06572415 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,769E-03 0,06552003 ! spindle assembly GO:0051225 6 5 0,000 8,769E-03 0,06531719 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 8,769E-03 0,06511559 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,769E-03 0,06491523 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,769E-03 0,06471611 ! drug metabolic process GO:0017144 6 5 0,000 8,769E-03 0,0645182 ! stem cell division GO:0017145 11 5 0,000 8,769E-03 0,0643215 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 8,769E-03 0,06412599 ! organ regeneration GO:0031100 7 5 0,000 8,769E-03 0,06393167 ! carnitine metabolic process GO:0009437 7 5 0,000 8,769E-03 0,06373852 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 8,769E-03 0,06354654 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,769E-03 0,06335571 ! cellular lipid catabolic process GO:0044242 134 80 1,000 8,796E-03 0,06335971 ! cell-substrate adhesion GO:0031589 171 81 1,000 9,008E-03 0,06469738 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 9,008E-03 0,06450483 ! negative regulation of growth GO:0045926 155 84 1,000 9,66E-03 0,06896458 ! one-carbon metabolic process GO:0006730 154 85 1,000 9,881E-03 0,07033869 ! positive regulation of cell activation GO:0050867 145 85 1,000 9,881E-03 0,0701312 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 154 87 1,000 0,0103315 0,07311055 GO:0070201|regulation of establishment of protein localization, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01051334 0,0741792 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01051334 0,0739623 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01051334 0,07374667 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01051334 0,07353229 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01051334 0,07331915 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01051334 0,07310725 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01051334 0,07289656 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01051334 0,07268709 ! sleep GO:0030431 13 6 0,000 0,01051334 0,07247882 ! response to oxygen radical GO:0000305 11 6 0,000 0,01051334 0,07227174 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01051334 0,07206583 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01051334 0,0718611 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01051334 0,07165753 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01051334 0,07145511 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01051334 0,07125382 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01051334 0,07105367 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01051334 0,07085464 ! forebrain regionalization GO:0021871 8 6 0,000 0,01051334 0,07065672 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01051334 0,07045991 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01051334 0,07026419 ! response to zinc ion GO:0010043 9 6 0,000 0,01051334 0,07006955 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01051334 0,06987599 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01051334 0,06968349 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01051334 0,06949205 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01051334 0,06930166 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01051334 0,06911232 ! malate metabolic process GO:0006108 11 6 0,000 0,01051334 0,068924 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01051334 0,0687367 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01051334 0,06855043 ! protein refolding GO:0042026 15 6 0,000 0,01051334 0,06836516 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01051334 0,06818088 ! opsonization GO:0008228 8 6 0,000 0,01051334 0,0679976 ! mating behavior GO:0007617 7 6 0,000 0,01051334 0,0678153 ! neuron remodeling GO:0016322 15 6 0,000 0,01051334 0,06763398 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01051334 0,06745362 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01051334 0,06727422 ! equilibrioception GO:0050957 14 6 0,000 0,01051334 0,06709578 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01051334 0,06691827 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01051334 0,06674171 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01051334 0,06656607 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01051334 0,06639136 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01051334 0,06621756 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01051334 0,06604467 ! toxin metabolic process GO:0009404 11 6 0,000 0,01051334 0,06587268 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01051334 0,06570158 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01051334 0,06553137 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01051334 0,06536203 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01051334 0,06519358 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01051334 0,06502598 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01051334 0,06485925 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01051334 0,06469337 ! thymic T cell selection GO:0045061 12 6 0,000 0,01051334 0,06452834 ! protein lipoylation GO:0009249 10 6 0,000 0,01051334 0,06436414 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01051334 0,06420078 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01051334 0,06403825 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01051334 0,06387653 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01051334 0,06371564 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01051334 0,06355555 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01051334 0,06339626 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01051334 0,06323777 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01051334 0,06308007 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01051334 0,06292315 ! hyperosmotic response GO:0006972 9 6 0,000 0,01051334 0,06276702 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01051334 0,06261165 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01051334 0,06245706 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01051334 0,06230322 ! urea metabolic process GO:0019627 7 6 0,000 0,01051334 0,06215014 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01051334 0,06199781 ! neutrophil activation GO:0042119 8 6 0,000 0,01051334 0,06184623 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01051334 0,06169538 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01051334 0,06154527 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01051334 0,06139589 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01051334 0,06124723 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01051334 0,06109929 ! neuron apoptosis GO:0051402 9 6 0,000 0,01051334 0,06095207 ! nucleoside salvage GO:0043174 9 6 0,000 0,01051334 0,06080555 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01051334 0,06065973 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01051334 0,06051461 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01051334 0,06037018 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01051334 0,06022645 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01051334 0,06008339 ! carnitine transport GO:0015879 10 6 0,000 0,01051334 0,05994101 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01051334 0,05979931 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01051334 0,05965827 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01051334 0,0595179 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01051334 0,05937819 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01051334 0,05923913 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01051334 0,05910072 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01051334 0,05896295 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01051334 0,05882583 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01051334 0,05868934 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01051334 0,05855349 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01051334 0,05841826 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01051334 0,05828366 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01051334 0,05814967 ! neural nucleus development GO:0048857 14 6 0,000 0,01051334 0,0580163 ! response to UV-C GO:0010225 11 6 0,000 0,01051334 0,05788354 ! astrocyte development GO:0014002 15 6 0,000 0,01051334 0,05775139 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01051334 0,05761983 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01051334 0,05748888 ! interaction with symbiont GO:0051702 13 6 0,000 0,01051334 0,05735852 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01051334 0,05722875 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01051334 0,05709957 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01051334 0,05697096 ! response to copper ion GO:0046688 10 6 0,000 0,01051334 0,05684294 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01051334 0,05671549 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01051334 0,05658861 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01051334 0,05646229 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01051334 0,05633654 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01051334 0,05621135 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01051334 0,05608671 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01051334 0,05596263 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01051334 0,05583909 ! hair follicle maturation GO:0048820 7 6 0,000 0,01051334 0,0557161 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01051334 0,05559364 ! Schwann cell development GO:0014044 15 6 0,000 0,01051334 0,05547173 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01051334 0,05535034 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01051334 0,05522949 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01051334 0,05510917 ! subpallium development GO:0021544 10 6 0,000 0,01051334 0,05498936 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01051334 0,05487008 ! histone ubiquitination GO:0016574 8 6 0,000 0,01051334 0,05475131 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01051334 0,05463306 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01051334 0,05451532 ! G2 phase GO:0051319 16 6 0,000 0,01051334 0,05439808 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01051334 0,05428135 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01051334 0,05416511 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01051334 0,05404937 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01051334 0,05393413 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01051334 0,05381938 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01051334 0,05370511 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01051334 0,05359133 ! receptor internalization GO:0031623 10 6 0,000 0,01051334 0,05347803 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01051334 0,05336521 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01051334 0,05325286 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01051334 0,05314098 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01051334 0,05302958 ! protein deubiquitination GO:0016579 14 6 0,000 0,01051334 0,05291863 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01051334 0,05280816 ! protein destabilization GO:0031648 9 6 0,000 0,01051334 0,05269814 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01051334 0,05258858 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01051334 0,05247948 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01051334 0,05237082 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01051334 0,05226262 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01051334 0,05215486 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01051334 0,05204755 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01051334 0,05194067 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01051334 0,05183424 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01051334 0,05172824 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01051334 0,05162267 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01051334 0,05151753 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01051334 0,05141282 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01051334 0,05130853 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01051334 0,05120467 ! catecholamine transport GO:0051937 9 6 0,000 0,01051334 0,05110123 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01051334 0,0509982 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01051334 0,05089559 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01051334 0,05079339 ! maternal placenta development GO:0001893 12 6 0,000 0,01051334 0,0506916 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01051334 0,05059021 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01051334 0,05048924 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01051334 0,05038866 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01051334 0,05028848 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01051334 0,05018871 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01051334 0,05008932 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01051334 0,04999033 ! sex differentiation GO:0007548 145 90 1,000 0,01102355 0,05231293 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01222119 0,05788225 ! tRNA transcription GO:0009304 14 7 0,000 0,01225499 0,05792832 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01225499 0,05781474 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01225499 0,05770159 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01225499 0,0575889 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01225499 0,05747664 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01225499 0,05736481 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01225499 0,05725343 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01225499 0,05714247 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01225499 0,05703194 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01225499 0,05692184 ! prostate gland development GO:0030850 13 7 0,000 0,01225499 0,05681217 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01225499 0,05670291 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01225499 0,05659408 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01225499 0,05648566 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01225499 0,05637766 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01225499 0,05627007 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01225499 0,05616289 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01225499 0,05605611 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01225499 0,05594974 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01225499 0,05584378 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01225499 0,05573821 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01225499 0,05563305 ! glycolipid transport GO:0046836 10 7 0,000 0,01225499 0,05552828 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01225499 0,0554239 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01225499 0,05531992 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01225499 0,05521632 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01225499 0,05511311 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01225499 0,05501029 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01225499 0,05490785 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01225499 0,05480579 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01225499 0,05470411 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01225499 0,05460281 ! mRNA stabilization GO:0048255 18 7 0,000 0,01225499 0,05450188 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01225499 0,05440132 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01225499 0,05430113 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01225499 0,05420131 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01225499 0,05410186 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01225499 0,05400277 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01225499 0,05390405 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01225499 0,05380568 ! lipoprotein transport GO:0042953 14 7 0,000 0,01225499 0,05370768 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01225499 0,05361003 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01225499 0,05351273 ! rhythmic behavior GO:0007622 15 7 0,000 0,01225499 0,05341579 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01225499 0,0533192 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01225499 0,05322295 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01225499 0,05312705 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01225499 0,0530315 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01225499 0,05293629 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01225499 0,05284142 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01225499 0,0527469 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01225499 0,05265271 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01225499 0,05255885 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01225499 0,05246533 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01225499 0,05237214 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01225499 0,05227928 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01225499 0,05218675 ! spinal cord patterning GO:0021511 13 7 0,000 0,01225499 0,05209455 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01225499 0,05200267 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01225499 0,05191112 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01225499 0,05181989 ! adrenal gland development GO:0030325 17 7 0,000 0,01225499 0,05172897 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01225499 0,05163838 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01225499 0,0515481 ! ovulation GO:0030728 9 7 0,000 0,01225499 0,05145814 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01225499 0,05136849 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01225499 0,05127916 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01225499 0,05119013 ! microtubule nucleation GO:0007020 20 7 0,000 0,01225499 0,05110141 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01225499 0,051013 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01225499 0,0509249 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01225499 0,05083709 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01225499 0,0507496 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01225499 0,0506624 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01225499 0,0505755 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01225499 0,0504889 ! galactose metabolic process GO:0006012 13 7 0,000 0,01225499 0,05040259 ! vesicle fusion GO:0006906 17 7 0,000 0,01225499 0,05031658 ! response to dietary excess GO:0002021 8 7 0,000 0,01225499 0,05023086 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01225499 0,05014543 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01225499 0,0500603 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01225499 0,04997545 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01225499 0,04989089 ! organ growth GO:0035265 15 7 0,000 0,01225499 0,04980661 ! purine salvage GO:0043101 10 7 0,000 0,01225499 0,04972262 ! nucleoside transport GO:0015858 8 7 0,000 0,01225499 0,04963891 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01225499 0,04955549 ! parturition GO:0007567 14 7 0,000 0,01225499 0,04947234 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01225499 0,04938947 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01225499 0,04930688 ! spindle checkpoint GO:0031577 15 7 0,000 0,01225499 0,04922457 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01225499 0,04914252 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01225499 0,04906076 ! macrophage differentiation GO:0030225 11 7 0,000 0,01225499 0,04897926 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01225499 0,04889803 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01225499 0,04881708 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01225499 0,04873639 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01225499 0,04865597 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01225499 0,04857581 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01225499 0,04849591 ! fibrinolysis GO:0042730 10 7 0,000 0,01225499 0,04841628 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01225499 0,04833691 ! eating behavior GO:0042755 7 7 0,000 0,01225499 0,0482578 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01225499 0,04817895 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01225499 0,04810035 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01225499 0,04802201 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01225499 0,04794393 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01225499 0,0478661 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01225499 0,04778852 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01225499 0,04771119 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01225499 0,04763411 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01225499 0,04755728 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01225499 0,0474807 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01225499 0,04740436 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01225499 0,04732827 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01225499 0,04725243 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01225499 0,04717682 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01225499 0,04710146 ! regulation of meiosis GO:0040020 12 7 0,000 0,01225499 0,04702634 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01225499 0,04695146 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01225499 0,04687681 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01225499 0,0468024 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01225499 0,04672823 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01225499 0,0466543 ! transcription termination GO:0006353 13 7 0,000 0,01225499 0,04658059 ! response to tumor cell GO:0002347 13 7 0,000 0,01225499 0,04650712 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01225499 0,04643388 ! anaphase GO:0051322 17 7 0,000 0,01225499 0,04636087 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01225499 0,04628809 ! axonal fasciculation GO:0007413 18 7 0,000 0,01225499 0,04621554 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01225499 0,04614322 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01225499 0,04607112 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01225499 0,04599924 ! diuresis GO:0030146 12 7 0,000 0,01225499 0,04592759 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01225499 0,04585617 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01225499 0,04578496 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01225499 0,04571398 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01225499 0,04564321 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01225499 0,04557267 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01225499 0,04550234 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01225499 0,04543223 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01225499 0,04536233 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01225499 0,04529265 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01225499 0,04522318 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01225499 0,04515393 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01225499 0,04508489 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01225499 0,04501605 ! lymph node development GO:0048535 10 7 0,000 0,01225499 0,04494743 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01225499 0,04487902 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01225499 0,04481081 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01225499 0,04474281 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01225499 0,04467502 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01225499 0,04460744 ! adult feeding behavior GO:0008343 9 7 0,000 0,01225499 0,04454005 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01225499 0,04447287 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01225499 0,0444059 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01225499 0,04433912 ! muscle adaptation GO:0043500 14 7 0,000 0,01225499 0,04427254 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01225499 0,04420617 ! retina homeostasis GO:0001895 12 7 0,000 0,01225499 0,04413999 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01225499 0,04407401 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01225499 0,04400823 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01225499 0,04394265 ! protein prenylation GO:0018342 18 7 0,000 0,01225499 0,04387725 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01225499 0,04381206 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01225499 0,04374705 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01225499 0,04368224 ! mRNA transport GO:0051028 169 96 1,000 0,01246728 0,04437319 ! regulation of protein localization GO:0032880 176 97 1,000 0,01271554 0,04518993 ! interphase GO:0051325 213 98 1,000 0,01296595 0,04601193 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01399363 0,04958569 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01399363 0,04951277 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01399363 0,04944007 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01399363 0,04936757 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01399363 0,04929529 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01399363 0,04922322 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01399363 0,04915137 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01399363 0,04907972 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01399363 0,04900828 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01399363 0,04893704 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01399363 0,04886602 ! meiotic prophase I GO:0007128 13 8 0,000 0,01399363 0,0487952 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01399363 0,04872458 ! oligopeptide transport GO:0006857 15 8 0,000 0,01399363 0,04865417 ! UTP metabolic process GO:0046051 8 8 0,000 0,01399363 0,04858396 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01399363 0,04851396 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01399363 0,04844415 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01399363 0,04837455 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01399363 0,04830514 ! succinate metabolic process GO:0006105 14 8 0,000 0,01399363 0,04823594 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01399363 0,04816693 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01399363 0,04809812 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01399363 0,04802951 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01399363 0,04796109 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01399363 0,04789287 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01399363 0,04782484 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01399363 0,047757 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01399363 0,04768936 ! reflex GO:0060004 16 8 0,000 0,01399363 0,0476219 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01399363 0,04755464 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01399363 0,04748757 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01399363 0,04742068 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01399363 0,04735399 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01399363 0,04728748 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01399363 0,04722116 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01399363 0,04715502 ! pigment granule organization GO:0048753 16 8 0,000 0,01399363 0,04708907 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01399363 0,0470233 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01399363 0,04695772 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01399363 0,04689232 ! histidine metabolic process GO:0006547 16 8 0,000 0,01399363 0,0468271 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01399363 0,04676206 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01399363 0,04669721 ! glycine catabolic process GO:0006546 13 8 0,000 0,01399363 0,04663253 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01399363 0,04656803 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01399363 0,04650371 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01399363 0,04643957 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01399363 0,0463756 ! melanin metabolic process GO:0006582 15 8 0,000 0,01399363 0,04631181 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01399363 0,04624819 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01399363 0,04618475 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01399363 0,04612149 ! macrophage activation GO:0042116 12 8 0,000 0,01399363 0,04605839 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01399363 0,04599547 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01399363 0,04593272 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01399363 0,04587014 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01399363 0,04580774 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01399363 0,0457455 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01399363 0,04568343 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01399363 0,04562153 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01399363 0,04555979 ! osteoblast development GO:0002076 16 8 0,000 0,01399363 0,04549822 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01399363 0,04543682 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01399363 0,04537559 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01399363 0,04531452 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01399363 0,04525361 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01399363 0,04519287 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01399363 0,04513229 ! response to UV-B GO:0010224 16 8 0,000 0,01399363 0,04507187 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01399363 0,04501161 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01399363 0,04495152 ! intermediate filament organization GO:0045109 12 8 0,000 0,01399363 0,04489158 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01399363 0,0448318 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01399363 0,04477219 ! cellular extravasation GO:0045123 12 8 0,000 0,01399363 0,04471273 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01399363 0,04465343 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01399363 0,04459429 ! response to antibiotic GO:0046677 11 8 0,000 0,01399363 0,0445353 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01399363 0,04447647 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01399363 0,04441779 ! DNA topological change GO:0006265 12 8 0,000 0,01399363 0,04435927 ! response to tropane GO:0014073 15 8 0,000 0,01399363 0,0443009 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01399363 0,04424269 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01399363 0,04418463 ! melanosome transport GO:0032402 13 8 0,000 0,01399363 0,04412672 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01399363 0,04406896 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01399363 0,04401135 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01399363 0,0439539 ! mast cell activation GO:0045576 14 8 0,000 0,01399363 0,04389659 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01399363 0,04383943 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01399363 0,04378243 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01399363 0,04372557 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01399363 0,04366885 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01399363 0,04361229 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01399363 0,04355587 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01399363 0,04349959 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01399363 0,04344347 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01399363 0,04338748 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01399363 0,04333164 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01399363 0,04327595 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01399363 0,04322039 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01399363 0,04316498 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01399363 0,04310971 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01399363 0,04305459 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01399363 0,0429996 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01399363 0,04294475 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01399363 0,04289005 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01399363 0,04283548 ! hormone catabolic process GO:0042447 17 8 0,000 0,01399363 0,04278105 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01399363 0,04272676 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01399363 0,04267261 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01399363 0,04261859 ! blastocyst growth GO:0001832 19 8 0,000 0,01399363 0,04256471 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01399363 0,04251097 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01399363 0,04245736 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01399363 0,04240389 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01399363 0,04235055 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01399363 0,04229734 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01399363 0,04224427 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01399363 0,04219134 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01399363 0,04213853 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01399363 0,04208586 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01399363 0,04203332 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01399363 0,0419809 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01399363 0,04192862 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01399363 0,04187647 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01399363 0,04182445 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01399363 0,04177256 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01399363 0,0417208 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01399363 0,04166917 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01572927 0,04677952 ! axon extension GO:0048675 15 9 0,000 0,01572927 0,04672177 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01572927 0,04666416 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01572927 0,04660669 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01572927 0,04654936 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01572927 0,04649218 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01572927 0,04643513 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01572927 0,04637822 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01572927 0,04632146 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01572927 0,04626483 ! phosphate transport GO:0006817 19 9 0,000 0,01572927 0,04620834 ! reproductive behavior GO:0019098 19 9 0,000 0,01572927 0,04615199 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01572927 0,04609578 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01572927 0,0460397 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01572927 0,04598376 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01572927 0,04592795 ! GTP metabolic process GO:0046039 9 9 0,000 0,01572927 0,04587228 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01572927 0,04581675 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01572927 0,04576134 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01572927 0,04570608 ! artery development GO:0060840 24 9 0,000 0,01572927 0,04565094 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01572927 0,04559594 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01572927 0,04554107 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01572927 0,04548634 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01572927 0,04543173 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01572927 0,04537726 ! chemosensory behavior GO:0007635 20 9 0,000 0,01572927 0,04532291 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01572927 0,0452687 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01572927 0,04521461 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01572927 0,04516066 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01572927 0,04510683 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01572927 0,04505313 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01572927 0,04499956 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01572927 0,04494612 ! protein targeting to ER GO:0045047 22 9 0,000 0,01572927 0,0448928 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01572927 0,04483961 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01572927 0,04478655 ! T cell selection GO:0045058 23 9 0,000 0,01572927 0,04473361 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01572927 0,04468079 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01572927 0,0446281 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01572927 0,04457554 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01572927 0,0445231 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01572927 0,04447078 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01572927 0,04441858 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01572927 0,04436651 ! mannose metabolic process GO:0006013 13 9 0,000 0,01572927 0,04431456 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01572927 0,04426273 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01572927 0,04421102 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01572927 0,04415943 ! receptor clustering GO:0043113 18 9 0,000 0,01572927 0,04410796 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01572927 0,04405661 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01572927 0,04400539 ! ruffle organization GO:0031529 15 9 0,000 0,01572927 0,04395428 ! retinol metabolic process GO:0042572 18 9 0,000 0,01572927 0,04390328 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01572927 0,04385241 ! behavioral fear response GO:0001662 22 9 0,000 0,01572927 0,04380166 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01572927 0,04375102 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01572927 0,0437005 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01572927 0,04365009 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01572927 0,04359981 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01572927 0,04354963 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01572927 0,04349958 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01572927 0,04344963 ! segment specification GO:0007379 13 9 0,000 0,01572927 0,04339981 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01572927 0,04335009 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01572927 0,04330049 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01572927 0,04325101 ! response to amine stimulus GO:0014075 13 9 0,000 0,01572927 0,04320163 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01572927 0,04315237 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01572927 0,04310323 ! erythrocyte development GO:0048821 15 9 0,000 0,01572927 0,04305419 ! gas homeostasis GO:0033483 16 9 0,000 0,01572927 0,04300526 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01572927 0,04295645 ! renal water homeostasis GO:0003091 14 9 0,000 0,01572927 0,04290775 ! postreplication repair GO:0006301 22 9 0,000 0,01572927 0,04285915 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01572927 0,04281067 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01572927 0,0427623 ! icosanoid secretion GO:0032309 15 9 0,000 0,01572927 0,04271403 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01572927 0,04266588 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01572927 0,04261783 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01572927 0,04256989 ! regulation of cell division GO:0051302 15 9 0,000 0,01572927 0,04252206 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01572927 0,04247433 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01572927 0,04242672 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01572927 0,04237921 ! sterol catabolic process GO:0016127 11 9 0,000 0,01572927 0,0423318 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01572927 0,0422845 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01572927 0,04223731 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01572927 0,04219022 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01572927 0,04214324 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01572927 0,04209636 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01572927 0,04204959 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01572927 0,04200292 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01572927 0,04195635 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01572927 0,04190989 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01572927 0,04186353 ! purine base metabolic process GO:0006144 21 9 0,000 0,01572927 0,04181727 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01572927 0,04177112 ! pigment granule transport GO:0051904 17 9 0,000 0,01572927 0,04172506 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01572927 0,04167911 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01572927 0,04163326 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01572927 0,04158751 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01572927 0,04154186 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01572927 0,04149631 ! mitochondrion localization GO:0051646 15 9 0,000 0,01572927 0,04145086 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01746191 0,04596648 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01746191 0,04591625 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01746191 0,04586612 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01746191 0,0458161 ! synapsis GO:0007129 13 10 0,000 0,01746191 0,04576619 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01746191 0,04571639 ! N-glycan processing GO:0006491 20 10 0,000 0,01746191 0,0456667 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01746191 0,04561712 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01746191 0,04556764 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01746191 0,04551827 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01746191 0,04546901 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01746191 0,04541985 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01746191 0,0453708 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01746191 0,04532186 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01746191 0,04527302 ! androgen metabolic process GO:0008209 17 10 0,000 0,01746191 0,04522429 ! phospholipid efflux GO:0033700 16 10 0,000 0,01746191 0,04517566 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01746191 0,04512714 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01746191 0,04507872 ! lung alveolus development GO:0048286 26 10 0,000 0,01746191 0,0450304 ! pathogenesis GO:0009405 13 10 0,000 0,01746191 0,04498219 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01746191 0,04493408 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01746191 0,04488607 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01746191 0,04483817 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01746191 0,04479037 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01746191 0,04474267 ! endoderm development GO:0007492 16 10 0,000 0,01746191 0,04469507 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01746191 0,04464757 ! arginine catabolic process GO:0006527 13 10 0,000 0,01746191 0,04460018 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01746191 0,04455288 ! proline metabolic process GO:0006560 13 10 0,000 0,01746191 0,04450568 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01746191 0,04445859 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01746191 0,04441159 ! V(D)J recombination GO:0033151 28 10 0,000 0,01746191 0,04436469 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01746191 0,0443179 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01746191 0,0442712 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01746191 0,0442246 ! B cell proliferation GO:0042100 18 10 0,000 0,01746191 0,04417809 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01746191 0,04413169 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01746191 0,04408538 ! multicellular organism growth GO:0035264 18 10 0,000 0,01746191 0,04403917 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01746191 0,04399305 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01746191 0,04394703 ! epithelial cell development GO:0002064 20 10 0,000 0,01746191 0,04390111 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01746191 0,04385529 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01746191 0,04380956 ! macroautophagy GO:0016236 17 10 0,000 0,01746191 0,04376392 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01746191 0,04371838 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01746191 0,04367294 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01746191 0,04362759 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01746191 0,04358233 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01746191 0,04353717 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01746191 0,0434921 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01746191 0,04344712 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01746191 0,04340224 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01746191 0,04335745 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01746191 0,04331275 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01746191 0,04326814 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01746191 0,04322363 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01746191 0,0431792 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01746191 0,04313487 ! response to dsRNA GO:0043331 20 10 0,000 0,01746191 0,04309063 ! DNA ligation GO:0006266 19 10 0,000 0,01746191 0,04304648 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01746191 0,04300242 ! melanosome localization GO:0032400 16 10 0,000 0,01746191 0,04295845 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01746191 0,04291457 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01746191 0,04287078 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01746191 0,04282708 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01746191 0,04278347 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01746191 0,04273994 ! mRNA cleavage GO:0006379 17 10 0,000 0,01746191 0,04269651 ! protein sumoylation GO:0016925 15 10 0,000 0,01746191 0,04265316 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01746191 0,0426099 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01746191 0,04256673 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01746191 0,04252365 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01746191 0,04248065 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01746191 0,04243774 ! salivary gland development GO:0007431 27 10 0,000 0,01746191 0,04239492 ! prophase GO:0051324 15 10 0,000 0,01746191 0,04235218 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01746191 0,04230953 ! apical protein localization GO:0045176 15 10 0,000 0,01746191 0,04226697 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01746191 0,04222449 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01746191 0,04218209 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01746191 0,04213978 ! midbrain development GO:0030901 13 10 0,000 0,01746191 0,04209756 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01746191 0,04205542 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01746191 0,04201337 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01746191 0,04197139 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01746191 0,04192951 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01746191 0,0418877 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01746191 0,04184598 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01746191 0,04180434 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01746191 0,04176279 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01746191 0,04172132 ! oocyte development GO:0048599 17 10 0,000 0,01746191 0,04167993 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01746191 0,04163862 ! blastocyst formation GO:0001825 17 10 0,000 0,01746191 0,04159739 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01746191 0,04155625 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01746191 0,04151518 ! activation of innate immune response GO:0002218 12 10 0,000 0,01746191 0,0414742 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01746191 0,0414333 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01746191 0,04139248 ! response to nicotine GO:0035094 20 10 0,000 0,01746191 0,04135174 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01746191 0,04131108 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01746191 0,0412705 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01746191 0,04123 ! localization within membrane GO:0051668 20 10 0,000 0,01746191 0,04118957 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01919156 0,04522517 ! respiratory burst GO:0045730 17 11 0,000 0,01919156 0,04518092 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01919156 0,04513675 ! neuron fate specification GO:0048665 17 11 0,000 0,01919156 0,04509267 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01919156 0,04504868 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01919156 0,04500477 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01919156 0,04496095 ! thyroid gland development GO:0030878 26 11 0,000 0,01919156 0,04491722 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01919156 0,04487357 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01919156 0,04483 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01919156 0,04478652 ! response to pain GO:0048265 24 11 0,000 0,01919156 0,04474312 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01919156 0,04469981 ! T cell proliferation GO:0042098 26 11 0,000 0,01919156 0,04465658 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01919156 0,04461343 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01919156 0,04457037 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01919156 0,04452739 ! bone resorption GO:0045453 16 11 0,000 0,01919156 0,04448449 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01919156 0,04444167 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01919156 0,04439894 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01919156 0,04435629 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01919156 0,04431372 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01919156 0,04427124 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01919156 0,04422883 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01919156 0,04418651 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01919156 0,04414426 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01919156 0,0441021 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01919156 0,04406002 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01919156 0,04401802 ! lipid digestion GO:0044241 18 11 0,000 0,01919156 0,04397609 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01919156 0,04393425 ! UV protection GO:0009650 19 11 0,000 0,01919156 0,04389249 ! adult heart development GO:0007512 14 11 0,000 0,01919156 0,04385081 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01919156 0,0438092 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01919156 0,04376768 ! temperature homeostasis GO:0001659 17 11 0,000 0,01919156 0,04372623 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01919156 0,04368486 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01919156 0,04364357 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01919156 0,04360236 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01919156 0,04356123 ! regulation of organ growth GO:0046620 13 11 0,000 0,01919156 0,04352017 ! pigment granule localization GO:0051875 20 11 0,000 0,01919156 0,04347919 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01919156 0,04343829 ! vasoconstriction GO:0042310 18 11 0,000 0,01919156 0,04339746 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01919156 0,04335671 ! embryonic axis specification GO:0000578 18 11 0,000 0,01919156 0,04331604 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01919156 0,04327544 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01919156 0,04323492 GO:0016180|snRNA processing, ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01919156 0,04319448 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01919156 0,04315411 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01919156 0,04311382 ! zymogen activation GO:0031638 15 11 0,000 0,01919156 0,0430736 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01919156 0,04303346 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01919156 0,04299339 ! nucleosome positioning GO:0016584 15 11 0,000 0,01919156 0,04295339 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01919156 0,04291347 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01919156 0,04287363 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01919156 0,04283386 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01919156 0,04279416 ! acid secretion GO:0046717 18 11 0,000 0,01919156 0,04275454 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01919156 0,04271499 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01919156 0,04267551 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01919156 0,0426361 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01919156 0,04259677 ! oocyte differentiation GO:0009994 18 11 0,000 0,01919156 0,04255751 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01919156 0,04251832 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01919156 0,04247921 ! cholesterol efflux GO:0033344 19 11 0,000 0,01919156 0,04244016 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01919156 0,04240119 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01919156 0,04236229 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01919156 0,04232346 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01919156 0,04228471 ! embryonic gut development GO:0048566 15 11 0,000 0,01919156 0,04224602 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01919156 0,0422074 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01919156 0,04216886 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01919156 0,04213038 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01919156 0,04209198 ! defense response to fungus GO:0050832 13 11 0,000 0,01919156 0,04205364 ! developmental induction GO:0031128 19 11 0,000 0,01919156 0,04201538 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01919156 0,04197718 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01919156 0,04193905 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01919156 0,041901 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01919156 0,04186301 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01919156 0,04182509 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01919156 0,04178724 ! nucleus localization GO:0051647 19 11 0,000 0,01919156 0,04174946 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01919156 0,04171174 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02091822 0,04542351 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02091822 0,04538255 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02091822 0,04534166 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02091822 0,04530085 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02091822 0,04526011 ! virus-host interaction GO:0019048 29 12 0,000 0,02091822 0,04521945 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02091822 0,04517886 ! cartilage condensation GO:0001502 20 12 0,000 0,02091822 0,04513834 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02091822 0,04509789 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02091822 0,04505752 ! protein complex disassembly GO:0043241 27 12 0,000 0,02091822 0,04501721 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02091822 0,04497698 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02091822 0,04493683 ! hippocampus development GO:0021766 26 12 0,000 0,02091822 0,04489674 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02091822 0,04485672 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02091822 0,04481678 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02091822 0,04477691 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02091822 0,04473711 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02091822 0,04469738 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02091822 0,04465771 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02091822 0,04461812 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02091822 0,0445786 ! drug transport GO:0015893 16 12 0,000 0,02091822 0,04453915 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02091822 0,04449977 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02091822 0,04446046 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02091822 0,04442122 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02091822 0,04438205 ! focal adhesion formation GO:0048041 35 12 0,000 0,02091822 0,04434295 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02091822 0,04430391 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02091822 0,04426495 ! forebrain cell migration GO:0021885 21 12 0,000 0,02091822 0,04422605 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02091822 0,04418722 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02091822 0,04414846 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02091822 0,04410977 ! entry into host cell GO:0030260 32 12 0,000 0,02091822 0,04407114 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02091822 0,04403258 ! monoamine transport GO:0015844 18 12 0,000 0,02091822 0,04399409 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02091822 0,04395567 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02091822 0,04391732 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02091822 0,04387903 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02091822 0,04384081 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02091822 0,04380265 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02091822 0,04376456 ! protein homotetramerization GO:0051289 21 12 0,000 0,02091822 0,04372654 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02091822 0,04368858 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02091822 0,04365069 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02091822 0,04361286 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02091822 0,0435751 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02091822 0,04353741 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02091822 0,04349978 ! cranial nerve development GO:0021545 20 12 0,000 0,02091822 0,04346221 ! fucose catabolic process GO:0019317 22 12 0,000 0,02091822 0,04342471 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02091822 0,04338728 ! histone acetylation GO:0016573 26 12 0,000 0,02091822 0,04334991 ! histone methylation GO:0016571 26 12 0,000 0,02091822 0,0433126 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02091822 0,04327536 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02091822 0,04323818 ! gland morphogenesis GO:0022612 29 12 0,000 0,02091822 0,04320107 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02091822 0,04316402 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02091822 0,04312703 ! T cell homeostasis GO:0043029 25 12 0,000 0,02091822 0,04309011 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02091822 0,04305325 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02091822 0,04301645 ! spleen development GO:0048536 22 12 0,000 0,02091822 0,04297971 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02091822 0,04294304 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02091822 0,04290643 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02091822 0,04286988 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02091822 0,0428334 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02091822 0,04279698 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02091822 0,04276062 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02091822 0,04272432 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02091822 0,04268808 ! response to cold GO:0009409 17 12 0,000 0,02091822 0,0426519 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02091822 0,04261579 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02091822 0,04257973 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0226419 0,04604938 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,0226419 0,04601049 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0226419 0,04597166 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0226419 0,0459329 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,0226419 0,0458942 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,0226419 0,04585557 ! lipid localization GO:0010876 28 13 0,000 0,0226419 0,045817 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,0226419 0,0457785 ! organelle fusion GO:0048284 32 13 0,000 0,0226419 0,04574006 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,0226419 0,04570169 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,0226419 0,04566338 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,0226419 0,04562514 ! endocrine pancreas development GO:0031018 22 13 0,000 0,0226419 0,04558696 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,0226419 0,04554884 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,0226419 0,04551079 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,0226419 0,0454728 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0226419 0,04543487 ! methionine metabolic process GO:0006555 27 13 0,000 0,0226419 0,04539701 ! plasma membrane organization GO:0007009 24 13 0,000 0,0226419 0,04535921 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,0226419 0,04532148 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,0226419 0,0452838 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,0226419 0,04524619 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,0226419 0,04520864 ! response to X-ray GO:0010165 25 13 0,000 0,0226419 0,04517116 ! cytokine metabolic process GO:0042107 22 13 0,000 0,0226419 0,04513373 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,0226419 0,04509637 ! exocrine system development GO:0035272 32 13 0,000 0,0226419 0,04505907 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,0226419 0,04502183 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,0226419 0,04498465 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,0226419 0,04494754 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,0226419 0,04491048 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,0226419 0,04487349 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,0226419 0,04483656 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,0226419 0,04479968 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,0226419 0,04476287 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,0226419 0,04472612 ! regulation of cellular pH GO:0030641 22 13 0,000 0,0226419 0,04468943 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0226419 0,0446528 ! ribosome assembly GO:0042255 17 13 0,000 0,0226419 0,04461623 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,0226419 0,04457972 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,0226419 0,04454327 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,0226419 0,04450687 ! chromatin silencing GO:0006342 26 13 0,000 0,0226419 0,04447054 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,0226419 0,04443427 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0226419 0,04439806 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0226419 0,0443619 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,0226419 0,04432581 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,0226419 0,04428977 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0226419 0,04425379 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,0226419 0,04421787 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,0226419 0,04418201 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,0226419 0,0441462 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,0226419 0,04411046 ! embryonic placenta development GO:0001892 23 13 0,000 0,0226419 0,04407477 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,0226419 0,04403914 ! insulin secretion GO:0030073 23 13 0,000 0,0226419 0,04400357 ! actin filament polymerization GO:0030041 24 13 0,000 0,0226419 0,04396805 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,0226419 0,04393259 ! acrosome reaction GO:0007340 18 13 0,000 0,0226419 0,04389719 ! rRNA transcription GO:0009303 25 14 0,000 0,0243626 0,04719519 ! lactation GO:0007595 26 14 0,000 0,0243626 0,04715722 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0243626 0,04711931 ! reproductive cellular process GO:0048610 20 14 0,000 0,0243626 0,04708146 ! tRNA modification GO:0006400 20 14 0,000 0,0243626 0,04704368 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0243626 0,04700595 ! regulation of S phase GO:0033261 23 14 0,000 0,0243626 0,04696829 ! water transport GO:0006833 21 14 0,000 0,0243626 0,04693068 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0243626 0,04689314 ! non-recombinational repair GO:0000726 25 14 0,000 0,0243626 0,04685565 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0243626 0,04681823 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0243626 0,04678086 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0243626 0,04674356 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0243626 0,04670631 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0243626 0,04666912 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0243626 0,046632 ! palate development GO:0060021 31 14 0,000 0,0243626 0,04659493 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0243626 0,04655792 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0243626 0,04652097 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0243626 0,04648408 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0243626 0,04644724 ! arginine metabolic process GO:0006525 17 14 0,000 0,0243626 0,04641047 ! regulation of heart rate GO:0002027 24 14 0,000 0,0243626 0,04637375 ! organic alcohol transport GO:0015850 29 14 0,000 0,0243626 0,04633709 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0243626 0,04630049 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0243626 0,04626395 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0243626 0,04622746 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0243626 0,04619103 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0243626 0,04615466 ! L-amino acid transport GO:0015807 30 14 0,000 0,0243626 0,04611835 ! bone mineralization GO:0030282 17 14 0,000 0,0243626 0,04608209 ! stem cell development GO:0048864 43 14 0,000 0,0243626 0,04604589 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0243626 0,04600975 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0243626 0,04597366 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0243626 0,04593763 ! cerebellum development GO:0021549 21 14 0,000 0,0243626 0,04590166 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0243626 0,04586574 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0243626 0,04582988 ! response to gamma radiation GO:0010332 28 14 0,000 0,0243626 0,04579408 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0243626 0,04575833 ! cofactor transport GO:0051181 26 14 0,000 0,0243626 0,04572264 ! NADP metabolic process GO:0006739 24 14 0,000 0,0243626 0,045687 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0243626 0,04565142 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0243626 0,04561589 ! intestinal absorption GO:0050892 25 14 0,000 0,0243626 0,04558042 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0243626 0,045545 ! oxygen transport GO:0015671 21 14 0,000 0,0243626 0,04550964 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0243626 0,04547434 ! male genitalia development GO:0030539 24 14 0,000 0,0243626 0,04543909 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0243626 0,04540389 ! regulation of axon extension GO:0030516 37 14 0,000 0,0243626 0,04536875 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,0243626 0,04533366 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0243626 0,04529863 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02608033 0,04845504 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02608033 0,04841765 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02608033 0,04838032 ! superoxide anion generation GO:0042554 20 15 0,000 0,02608033 0,04834305 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02608033 0,04830583 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02608033 0,04826867 ! copper ion transport GO:0006825 20 15 0,000 0,02608033 0,04823157 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02608033 0,04819453 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02608033 0,04815754 ! sulfate transport GO:0008272 23 15 0,000 0,02608033 0,04812061 ! response to cAMP GO:0051591 22 15 0,000 0,02608033 0,04808374 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02608033 0,04804692 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02608033 0,04801016 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02608033 0,04797345 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02608033 0,0479368 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02608033 0,04790021 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02608033 0,04786367 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02608033 0,04782719 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02608033 0,04779077 ! pituitary gland development GO:0021983 29 15 0,000 0,02608033 0,0477544 ! vesicle coating GO:0006901 33 15 0,000 0,02608033 0,04771808 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02608033 0,04768182 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02608033 0,04764562 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02608033 0,04760947 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02608033 0,04757337 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02608033 0,04753733 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02608033 0,04750134 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02608033 0,04746541 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02608033 0,04742954 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02608033 0,04739371 ! histone deacetylation GO:0016575 20 15 0,000 0,02608033 0,04735794 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02608033 0,04732223 ! tissue regeneration GO:0042246 26 15 0,000 0,02608033 0,04728657 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02608033 0,04725096 ! water homeostasis GO:0030104 27 15 0,000 0,02608033 0,04721541 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02608033 0,04717991 ! muscle maintenance GO:0046716 26 15 0,000 0,02608033 0,04714446 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02608033 0,04710907 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02608033 0,04707373 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02608033 0,04703844 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02608033 0,0470032 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02608033 0,04696802 ! cell killing GO:0001906 29 15 0,000 0,02608033 0,04693289 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02608033 0,04689781 ! detection of bacterium GO:0016045 18 15 0,000 0,02608033 0,04686279 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02608033 0,04682782 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02608033 0,0467929 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02608033 0,04675803 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02608033 0,04672321 ! peptide hormone processing GO:0016486 23 15 0,000 0,02608033 0,04668845 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02779509 0,04972118 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02779509 0,04968424 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02779509 0,04964736 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02779509 0,04961053 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02779509 0,04957375 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02779509 0,04953703 ! bone remodeling GO:0046849 27 16 0,000 0,02779509 0,04950036 ! filopodium assembly GO:0046847 32 16 0,000 0,02779509 0,04946375 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02779509 0,04942719 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02779509 0,04939069 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02779509 0,04935424 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02779509 0,04931784 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02779509 0,0492815 ! startle response GO:0001964 28 16 0,000 0,02779509 0,04924521 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02779509 0,04920897 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02779509 0,04917279 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02779509 0,04913666 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02779509 0,04910058 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02779509 0,04906456 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02779509 0,04902859 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02779509 0,04899267 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02779509 0,0489568 ! response to osmotic stress GO:0006970 25 16 0,000 0,02779509 0,04892099 ! lysosomal transport GO:0007041 26 16 0,000 0,02779509 0,04888523 ! fructose metabolic process GO:0006000 25 16 0,000 0,02779509 0,04884952 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02779509 0,04881386 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02779509 0,04877826 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02779509 0,0487427 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02779509 0,0487072 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02779509 0,04867175 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02779509 0,04863636 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02779509 0,04860101 ! DNA replication initiation GO:0006270 27 16 0,000 0,02779509 0,04856572 ! neuron recognition GO:0008038 35 16 0,000 0,02779509 0,04853047 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02779509 0,04849528 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02779509 0,04846014 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02779509 0,04842505 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02779509 0,04839001 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02779509 0,04835502 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02779509 0,04832008 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02779509 0,04828519 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02779509 0,04825035 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02779509 0,04821557 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02779509 0,04818083 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02779509 0,04814614 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02779509 0,0481115 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02779509 0,04807692 ! defense response to virus GO:0051607 37 16 0,000 0,02779509 0,04804238 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02950689 0,05096452 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02950689 0,05092796 ! metencephalon development GO:0022037 30 17 0,000 0,02950689 0,05089145 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02950689 0,050855 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02950689 0,0508186 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02950689 0,05078225 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02950689 0,05074595 ! signal complex assembly GO:0007172 41 17 0,000 0,02950689 0,0507097 ! endothelial cell migration GO:0043542 28 17 0,000 0,02950689 0,0506735 ! inositol metabolic process GO:0006020 28 17 0,000 0,02950689 0,05063736 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02950689 0,05060127 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02950689 0,05056523 ! glial cell development GO:0021782 27 17 0,000 0,02950689 0,05052924 ! limbic system development GO:0021761 36 17 0,000 0,02950689 0,0504933 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02950689 0,05045741 ! adult walking behavior GO:0007628 33 17 0,000 0,02950689 0,05042158 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02950689 0,05038579 ! heart looping GO:0001947 30 17 0,000 0,02950689 0,05035006 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02950689 0,05031437 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02950689 0,05027874 ! myoblast differentiation GO:0045445 45 17 0,000 0,02950689 0,05024316 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02950689 0,05020762 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02950689 0,05017214 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02950689 0,05013671 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02950689 0,05010133 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02950689 0,05006599 ! glycine metabolic process GO:0006544 28 17 0,000 0,02950689 0,05003071 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02950689 0,04999548 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02950689 0,0499603 ! NAD metabolic process GO:0019674 29 17 0,000 0,02950689 0,04992516 ! membrane budding GO:0006900 37 17 0,000 0,02950689 0,04989008 ! DNA integration GO:0015074 29 17 0,000 0,02950689 0,04985504 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02950689 0,04982006 ! regulation of protein binding GO:0043393 33 17 0,000 0,02950689 0,04978512 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02950689 0,04975023 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02950689 0,04971539 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02950689 0,0496806 ! genitalia development GO:0048806 30 17 0,000 0,02950689 0,04964586 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02950689 0,04961117 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02950689 0,04957652 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02950689 0,04954193 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02950689 0,04950738 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02950689 0,04947288 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02950689 0,04943843 ! steroid catabolic process GO:0006706 31 17 0,000 0,02950689 0,04940402 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02950689 0,04936967 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02950689 0,04933536 ! gas transport GO:0015669 25 17 0,000 0,02950689 0,0493011 ! organic cation transport GO:0015695 31 17 0,000 0,02950689 0,04926688 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02950689 0,04923272 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02950689 0,0491986 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02950689 0,04916453 ! microspike assembly GO:0030035 36 17 0,000 0,02950689 0,0491305 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02950689 0,04909653 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03121573 0,05190398 ! neuron maturation GO:0042551 42 18 0,000 0,03121573 0,05186813 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03121573 0,05183233 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03121573 0,05179659 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,03121573 0,05176089 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03121573 0,05172524 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03121573 0,05168964 ! memory GO:0007613 31 18 0,000 0,03121573 0,05165409 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03121573 0,05161859 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03121573 0,05158314 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03121573 0,05154774 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03121573 0,05151238 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03121573 0,05147708 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03121573 0,05144182 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03121573 0,05140661 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03121573 0,05137144 ! response to retinoic acid GO:0032526 26 18 0,000 0,03121573 0,05133633 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03121573 0,05130127 ! response to fungus GO:0009620 21 18 0,000 0,03121573 0,05126625 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03121573 0,05123128 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03121573 0,05119635 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03121573 0,05116148 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03121573 0,05112665 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03121573 0,05109187 ! vitamin transport GO:0051180 27 18 0,000 0,03121573 0,05105714 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03121573 0,05102245 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03121573 0,05098782 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03121573 0,05095322 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03121573 0,05091868 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03121573 0,05088418 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03121573 0,05084973 ! nerve development GO:0021675 28 18 0,000 0,03121573 0,05081533 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03121573 0,05078097 ! protein secretion GO:0009306 39 19 0,000 0,03292162 0,05351988 ! positive regulation of translation GO:0045727 30 19 0,000 0,03292162 0,05348374 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03292162 0,05344765 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03292162 0,05341161 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03292162 0,05337562 ! skin development GO:0043588 36 19 0,000 0,03292162 0,05333968 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03292162 0,05330378 ! lipid phosphorylation GO:0046834 35 19 0,000 0,03292162 0,05326794 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03292162 0,05323214 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03292162 0,05319639 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03292162 0,05316069 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03292162 0,05312503 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03292162 0,05308943 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03292162 0,05305387 ! cerebral cortex development GO:0021987 36 19 0,000 0,03292162 0,05301836 ! pigmentation during development GO:0048066 41 19 0,000 0,03292162 0,05298289 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03292162 0,05294747 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03292162 0,05291211 ! heme metabolic process GO:0042168 36 19 0,000 0,03292162 0,05287678 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03292162 0,05284151 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03292162 0,05280628 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03292162 0,0527711 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03292162 0,05273597 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03292162 0,05270088 ! peptide cross-linking GO:0018149 37 19 0,000 0,03292162 0,05266584 ! protein export from nucleus GO:0006611 36 19 0,000 0,03292162 0,05263085 ! heart process GO:0003015 30 19 0,000 0,03292162 0,0525959 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03292162 0,052561 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03292162 0,05252614 ! visual learning GO:0008542 36 19 0,000 0,03292162 0,05249133 ! cellular pigmentation GO:0033059 36 19 0,000 0,03292162 0,05245657 ! G1 phase GO:0051318 40 19 0,000 0,03292162 0,05242185 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03292162 0,05238718 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03292162 0,05235256 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03292162 0,05231798 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03292162 0,05228345 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03292162 0,05224896 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03292162 0,05221452 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03292162 0,05218012 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03292162 0,05214577 ! cilium assembly GO:0042384 37 19 0,000 0,03292162 0,05211146 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03292162 0,0520772 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03462456 0,05473502 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03462456 0,05469908 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03462456 0,05466319 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03462456 0,05462735 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03462456 0,05459155 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03462456 0,0545558 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03462456 0,05452009 ! response to vitamin GO:0033273 31 20 0,000 0,03462456 0,05448444 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03462456 0,05444882 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03462456 0,05441326 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03462456 0,05437774 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03462456 0,05434227 ! response to alkaloid GO:0043279 38 20 0,000 0,03462456 0,05430685 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03462456 0,05427147 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03462456 0,05423613 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03462456 0,05420085 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03462456 0,05416561 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03462456 0,05413041 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03462456 0,05409526 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03462456 0,05406016 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,03462456 0,0540251 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03462456 0,05399009 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03462456 0,05395512 ! body fluid secretion GO:0007589 31 20 0,000 0,03462456 0,0539202 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03462456 0,05388532 ! peptide secretion GO:0002790 35 20 0,000 0,03462456 0,05385049 ! stem cell differentiation GO:0048863 53 20 0,000 0,03462456 0,0538157 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03462456 0,05378096 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,03462456 0,05374626 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03462456 0,05371161 ! sensory perception of pain GO:0019233 30 20 0,000 0,03462456 0,053677 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03462456 0,05364243 ! diencephalon development GO:0021536 34 20 0,000 0,03462456 0,05360792 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03462456 0,05357344 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03462456 0,05353901 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03462456 0,05350463 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03462456 0,05347028 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03462456 0,05343599 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03462456 0,05340173 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03462456 0,05336752 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03462456 0,05333336 ! regulation of glucose import GO:0046324 29 20 0,000 0,03462456 0,05329923 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03462456 0,05326515 ! actin filament-based movement GO:0030048 43 20 0,000 0,03462456 0,05323112 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03462456 0,05319713 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03462456 0,05316318 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03462456 0,05312927 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03462456 0,05309541 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03462456 0,05306159 ! regulation of cell killing GO:0031341 42 21 0,000 0,03632456 0,05563138 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03632456 0,05559599 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03632456 0,05556065 ! hormone secretion GO:0046879 38 21 0,000 0,03632456 0,05552535 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03632456 0,0554901 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03632456 0,05545489 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03632456 0,05541972 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03632456 0,0553846 ! axis specification GO:0009798 38 21 0,000 0,03632456 0,05534953 ! ovarian follicle development GO:0001541 35 21 0,000 0,03632456 0,05531449 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03632456 0,05527951 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03632456 0,05524456 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03632456 0,05520967 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03632456 0,05517481 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03632456 0,05514 ! cell aging GO:0007569 44 21 0,000 0,03632456 0,05510523 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03632456 0,05507051 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03632456 0,05503583 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03632456 0,0550012 ! cytolysis GO:0019835 24 21 0,000 0,03632456 0,0549666 ! vasodilation GO:0042311 39 21 0,000 0,03632456 0,05493206 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03632456 0,05489755 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03632456 0,05486309 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03632456 0,05482867 ! oogenesis GO:0048477 36 21 0,000 0,03632456 0,0547943 ! DNA modification GO:0006304 34 21 0,000 0,03632456 0,05475996 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03632456 0,05472567 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03632456 0,05469143 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03632456 0,05465722 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03632456 0,05462306 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03632456 0,05458895 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03632456 0,05455487 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03632456 0,05452084 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03632456 0,05448685 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03632456 0,0544529 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03632456 0,05441899 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03632456 0,05438513 ! collagen catabolic process GO:0030574 28 21 0,000 0,03632456 0,05435131 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03632456 0,05431753 ! gut development GO:0048565 39 21 0,000 0,03632456 0,05428379 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03802163 0,05678463 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03802163 0,0567494 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03802163 0,05671422 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03802163 0,05667908 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03802163 0,05664398 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03802163 0,05660893 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03802163 0,05657392 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03802163 0,05653896 ! regeneration GO:0031099 41 22 0,000 0,03802163 0,05650404 ! keratinization GO:0031424 28 22 0,000 0,03802163 0,05646916 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03802163 0,05643432 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03802163 0,05639953 ! sensory perception of taste GO:0050909 28 22 0,000 0,03802163 0,05636478 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03802163 0,05633007 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,03802163 0,05629541 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03802163 0,05626078 ! vacuolar transport GO:0007034 36 22 0,000 0,03802163 0,0562262 ! lysosome organization GO:0007040 41 22 0,000 0,03802163 0,05619167 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03802163 0,05615717 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03802163 0,05612272 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03802163 0,05608831 ! fucose metabolic process GO:0006004 39 22 0,000 0,03802163 0,05605394 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03802163 0,05601962 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03802163 0,05598533 ! ureteric bud development GO:0001657 43 22 0,000 0,03802163 0,05595109 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03802163 0,05591689 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03802163 0,05588273 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03802163 0,05584862 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03802163 0,05581454 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03802163 0,05578051 ! sarcomere organization GO:0045214 30 22 0,000 0,03802163 0,05574652 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03802163 0,05571257 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03802163 0,05567866 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03802163 0,05564479 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03802163 0,05561096 ! protein stabilization GO:0050821 39 22 0,000 0,03802163 0,05557718 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03971576 0,05801828 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03971576 0,05798308 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03971576 0,05794791 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03971576 0,05791279 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03971576 0,05787772 ! gluconeogenesis GO:0006094 33 23 0,000 0,03971576 0,05784268 ! viral genome replication GO:0019079 41 23 0,000 0,03971576 0,05780769 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03971576 0,05777274 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03971576 0,05773783 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03971576 0,05770297 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03971576 0,05766814 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03971576 0,05763336 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03971576 0,05759862 ! visual behavior GO:0007632 42 23 0,000 0,03971576 0,05756392 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03971576 0,05752927 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03971576 0,05749465 ! response to ethanol GO:0045471 46 23 0,000 0,03971576 0,05746008 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03971576 0,05742555 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03971576 0,05739106 ! peroxisome organization GO:0007031 37 23 0,000 0,03971576 0,05735661 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03971576 0,0573222 ! vesicle targeting GO:0006903 43 23 0,000 0,03971576 0,05728784 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03971576 0,05725351 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03971576 0,05721923 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03971576 0,05718499 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03971576 0,05715078 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03971576 0,05711662 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03971576 0,0570825 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03971576 0,05704842 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03971576 0,05701439 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03971576 0,05698039 ! fatty acid transport GO:0015908 44 23 0,000 0,03971576 0,05694643 ! platelet activation GO:0030168 37 23 0,000 0,03971576 0,05691251 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03971576 0,05687864 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03971576 0,0568448 ! hormone transport GO:0009914 40 23 0,000 0,03971576 0,05681101 ! cell-cell recognition GO:0009988 25 23 0,000 0,03971576 0,05677725 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03971576 0,05674353 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03971576 0,05670986 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03971576 0,05667622 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03971576 0,05664263 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03971576 0,05660907 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04140696 0,05898469 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04140696 0,05894979 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,04140696 0,05891493 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04140696 0,05888011 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04140696 0,05884533 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04140696 0,05881059 ! vesicle docking GO:0048278 47 24 0,000 0,04140696 0,0587759 ! spinal cord development GO:0021510 47 24 0,000 0,04140696 0,05874124 ! vacuole organization GO:0007033 43 24 0,000 0,04140696 0,05870663 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04140696 0,05867205 ! digestive system process GO:0022600 39 24 0,000 0,04140696 0,05863752 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04140696 0,05860303 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04140696 0,05856858 ! regulation of behavior GO:0050795 43 24 0,000 0,04140696 0,05853416 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04140696 0,05849979 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04140696 0,05846546 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04140696 0,05843117 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04140696 0,05839692 ! membrane depolarization GO:0051899 39 24 0,000 0,04140696 0,05836271 ! pallium development GO:0021543 49 24 0,000 0,04140696 0,05832854 ! pentose metabolic process GO:0019321 35 24 0,000 0,04140696 0,05829441 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,04140696 0,05826032 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04140696 0,05822627 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04140696 0,05819226 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04140696 0,05815829 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04140696 0,05812436 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04140696 0,05809046 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04140696 0,05805661 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04140696 0,0580228 ! regulation of amine transport GO:0051952 40 24 0,000 0,04140696 0,05798903 ! protein tetramerization GO:0051262 52 24 0,000 0,04140696 0,05795529 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04309524 0,06028323 ! myelination GO:0042552 45 25 0,000 0,04309524 0,0602482 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04309524 0,06021321 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04309524 0,06017826 ! phototransduction GO:0007602 33 25 0,000 0,04309524 0,06014336 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,04309524 0,06010849 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,04309524 0,06007367 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,04309524 0,06003888 ! sperm motility GO:0030317 31 25 0,000 0,04309524 0,06000414 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,04309524 0,05996943 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,04309524 0,05993477 ! receptor metabolic process GO:0043112 46 25 0,000 0,04309524 0,05990014 ! chromosome condensation GO:0030261 45 25 0,000 0,04309524 0,05986556 ! response to starvation GO:0042594 42 25 0,000 0,04309524 0,05983102 ! osteoblast differentiation GO:0001649 60 25 0,000 0,04309524 0,05979651 ! neural crest cell development GO:0014032 54 25 0,000 0,04309524 0,05976205 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04309524 0,05972762 ! negative regulation of cell development GO:0010721 73 25 0,000 0,04309524 0,05969324 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04309524 0,05965889 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04309524 0,05962458 ! interaction with host GO:0051701 62 25 0,000 0,04309524 0,05959032 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04309524 0,05955609 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,04309524 0,0595219 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04309524 0,05948775 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04309524 0,05945364 ! immunoglobulin production GO:0002377 55 25 0,000 0,04309524 0,05941957 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04309524 0,05938554 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04309524 0,05935155 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,04309524 0,05931759 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,04309524 0,05928368 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04309524 0,0592498 ! telomere organization GO:0032200 43 25 0,000 0,04309524 0,05921596 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04309524 0,05918216 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04309524 0,0591484 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0447806 0,06142653 ! embryonic pattern specification GO:0009880 44 26 0,000 0,0447806 0,06139153 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0447806 0,06135657 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0447806 0,06132165 ! initiation of viral infection GO:0019059 57 26 0,000 0,0447806 0,06128677 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0447806 0,06125192 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0447806 0,06121712 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,0447806 0,06118236 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,0447806 0,06114764 ! molting cycle process GO:0022404 50 26 0,000 0,0447806 0,06111295 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,0447806 0,06107831 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0447806 0,0610437 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,0447806 0,06100914 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0447806 0,06097461 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0447806 0,06094012 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,0447806 0,06090567 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,0447806 0,06087126 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,0447806 0,06083689 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0447806 0,06080256 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,0447806 0,06076826 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0447806 0,06073401 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0447806 0,06069979 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0447806 0,06066562 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,0447806 0,06063148 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,0447806 0,06059738 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0447806 0,06056331 ! blastocyst development GO:0001824 49 26 0,000 0,0447806 0,06052929 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0447806 0,0604953 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,0447806 0,06046135 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0447806 0,06042744 ! neuron fate commitment GO:0048663 48 27 0,000 0,04646306 0,06266262 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04646306 0,06262751 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04646306 0,06259245 ! iron ion transport GO:0006826 59 27 0,000 0,04646306 0,06255742 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,04646306 0,06252243 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04646306 0,06248748 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04646306 0,06245258 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04646306 0,06241771 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04646306 0,06238287 ! fat cell differentiation GO:0045444 50 27 0,000 0,04646306 0,06234808 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04646306 0,06231333 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04646306 0,06227861 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04646306 0,06224394 ! autophagy GO:0006914 41 27 0,000 0,04646306 0,0622093 ! male gonad development GO:0008584 44 27 0,000 0,04646306 0,0621747 ! response to toxin GO:0009636 47 27 0,000 0,04646306 0,06214014 ! primary neural tube formation GO:0014020 51 27 0,000 0,04646306 0,06210562 ! base-excision repair GO:0006284 41 27 0,000 0,04646306 0,06207113 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04646306 0,06203669 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04646306 0,06200228 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04646306 0,06196791 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04646306 0,06193358 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04646306 0,06189929 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04646306 0,06186503 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04646306 0,06183081 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04646306 0,06179663 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,0481426 0,06399508 ! circadian rhythm GO:0007623 50 28 0,000 0,0481426 0,06395974 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,0481426 0,06392444 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,0481426 0,06388918 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,0481426 0,06385396 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,0481426 0,06381878 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,0481426 0,06378364 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,0481426 0,06374854 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,0481426 0,06371347 ! synaptogenesis GO:0007416 42 28 0,000 0,0481426 0,06367845 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,0481426 0,06364346 ! lipid oxidation GO:0034440 43 28 0,000 0,0481426 0,06360851 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,0481426 0,0635736 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,0481426 0,06353872 ! translational initiation GO:0006413 65 29 0,000 0,04981924 0,06571551 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,04981924 0,0656795 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04981924 0,06564353 ! regulation of pH GO:0006885 43 29 0,000 0,04981924 0,0656076 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04981924 0,06557171 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04981924 0,06553586 ! catechol metabolic process GO:0009712 54 29 0,000 0,04981924 0,06550005 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,04981924 0,06546428 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,04981924 0,06542854 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,04981924 0,06539285 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04981924 0,06535719 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,04981924 0,06532157 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04981924 0,065286 ! cell fate determination GO:0001709 60 29 0,000 0,04981924 0,06525046 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04981924 0,06521496 ! detection of light stimulus GO:0009583 38 29 0,000 0,04981924 0,06517949 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,04981924 0,06514407 ! tissue homeostasis GO:0001894 48 29 0,000 0,04981924 0,06510869 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,04981924 0,06507334 ! phenol metabolic process GO:0018958 55 30 0,000 0,05149298 0,06722307 ! zinc ion transport GO:0006829 45 30 0,000 0,05149298 0,06718661 ! membrane docking GO:0022406 61 30 0,000 0,05149298 0,0671502 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,05149298 0,06711382 ! cell junction assembly GO:0034329 78 30 0,000 0,05149298 0,06707749 ! regulation of innate immune response GO:0045088 51 30 0,000 0,05149298 0,06704119 ! acute-phase response GO:0006953 49 30 0,000 0,05149298 0,06700493 ! myofibril assembly GO:0030239 47 30 0,000 0,05149298 0,06696871 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,05149298 0,06693253 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,05149298 0,06689639 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,05149298 0,06686029 ! phospholipid transport GO:0015914 51 30 0,000 0,05149298 0,06682423 ! ensheathment of neurons GO:0007272 57 30 0,000 0,05149298 0,0667882 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,05149298 0,06675222 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,05149298 0,06671627 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,05149298 0,06668036 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,05149298 0,06664449 ! eye morphogenesis GO:0048592 60 30 0,000 0,05149298 0,06660866 ! response to heat GO:0009408 50 30 0,000 0,05149298 0,06657287 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05316383 0,06869612 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05316383 0,06865925 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05316383 0,06862241 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05316383 0,06858562 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05316383 0,06854886 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05316383 0,06851215 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,05316383 0,06847547 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05316383 0,06843883 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05316383 0,06840224 ! ovulation cycle process GO:0022602 49 31 0,000 0,05316383 0,06836568 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05316383 0,06832916 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,05316383 0,06829268 ! peptide transport GO:0015833 55 31 0,000 0,05316383 0,06825623 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,05316383 0,06821983 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05316383 0,06818347 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05316383 0,06814714 ! mesoderm formation GO:0001707 69 31 0,000 0,05316383 0,06811085 ! natural killer cell activation GO:0030101 45 31 0,000 0,05316383 0,0680746 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05316383 0,06803839 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05316383 0,06800222 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05316383 0,06796609 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05316383 0,06793 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05483179 0,07002404 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05483179 0,0699869 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05483179 0,06994979 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,05483179 0,06991272 ! cholesterol transport GO:0030301 56 32 0,000 0,05483179 0,06987569 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05483179 0,0698387 ! spliceosome assembly GO:0000245 67 32 0,000 0,05483179 0,06980175 ! spindle organization GO:0007051 46 32 0,000 0,05483179 0,06976483 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05483179 0,06972796 ! metanephros development GO:0001656 74 32 0,000 0,05483179 0,06969112 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05483179 0,06965433 ! response to ionizing radiation GO:0010212 65 32 0,000 0,05483179 0,06961757 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05483179 0,06958085 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05483179 0,06954417 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,05483179 0,06950753 ! muscle cell development GO:0055001 49 32 0,000 0,05483179 0,06947093 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05483179 0,06943437 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05483179 0,06939784 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05483179 0,06936136 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,05483179 0,06932491 ! ovulation cycle GO:0042698 51 32 0,000 0,05483179 0,0692885 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05483179 0,06925213 ! BMP signaling pathway GO:0030509 64 32 0,000 0,05483179 0,06921579 ! hindbrain development GO:0030902 61 32 0,000 0,05483179 0,0691795 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,05483179 0,06914324 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05483179 0,06910702 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,05483179 0,06907084 ! gene silencing GO:0016458 65 32 0,000 0,05483179 0,06903469 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,05649687 0,07109387 ! post-embryonic development GO:0009791 69 33 0,000 0,05649687 0,07105671 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,05649687 0,07101958 ! protein targeting to membrane GO:0006612 68 33 0,000 0,05649687 0,0709825 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,05649687 0,07094545 ! ceramide metabolic process GO:0006672 64 33 0,000 0,05649687 0,07090844 ! formation of primary germ layer GO:0001704 72 33 0,000 0,05649687 0,07087147 ! cell fate specification GO:0001708 52 33 0,000 0,05649687 0,07083454 ! sterol transport GO:0015918 57 33 0,000 0,05649687 0,07079765 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,05649687 0,07076079 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,05649687 0,07072397 ! adult locomotory behavior GO:0008344 59 33 0,000 0,05649687 0,0706872 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,05649687 0,07065046 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,05649687 0,07061376 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,05815908 0,07265355 ! glial cell differentiation GO:0010001 63 34 0,000 0,05815908 0,07261585 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,05815908 0,07257818 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,05815908 0,07254056 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,05815908 0,07250297 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,05815908 0,07246543 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,05815908 0,07242792 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,05815908 0,07239045 ! mismatch repair GO:0006298 46 34 0,000 0,05815908 0,07235302 ! spermatid development GO:0007286 63 34 0,000 0,05815908 0,07231563 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,05815908 0,07227827 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,05815908 0,07224096 ! placenta development GO:0001890 53 34 0,000 0,05815908 0,07220368 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,05815908 0,07216644 ! regulation of muscle development GO:0048634 70 35 0,000 0,0598184 0,07418715 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0598184 0,07414893 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0598184 0,07411075 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0598184 0,07407261 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0598184 0,07403451 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0598184 0,07399644 ! odontogenesis GO:0042476 66 35 0,000 0,0598184 0,07395842 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0598184 0,07392043 ! female gonad development GO:0008585 58 35 0,000 0,0598184 0,07388248 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0598184 0,07384458 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0598184 0,07380671 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,0598184 0,07376888 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0598184 0,07373109 ! cytokine production GO:0001816 59 35 0,000 0,0598184 0,07369333 ! neural tube formation GO:0001841 67 35 0,000 0,0598184 0,07365562 ! vesicle localization GO:0051648 64 35 0,000 0,0598184 0,07361794 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,06147486 0,07561785 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,06147486 0,07557921 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,06147486 0,07554061 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,06147486 0,07550205 ! cell junction organization GO:0034330 86 36 0,000 0,06147486 0,07546353 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,06147486 0,07542505 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,06147486 0,07538661 ! positive regulation of cell development GO:0010720 80 36 0,000 0,06147486 0,0753482 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,06147486 0,07530984 ! regulation of proteolysis GO:0030162 72 36 0,000 0,06147486 0,07527151 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,06147486 0,07523323 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,06147486 0,07519498 ! aerobic respiration GO:0009060 55 36 0,000 0,06147486 0,07515677 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,06147486 0,0751186 ! embryonic organ development GO:0048568 57 36 0,000 0,06147486 0,07508047 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,06147486 0,07504238 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,06147486 0,07500432 ! RNA export from nucleus GO:0006405 56 37 0,000 0,06312846 0,07698281 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,06312846 0,07694381 ! meiosis I GO:0007127 65 37 0,000 0,06312846 0,07690485 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,06312846 0,07686593 ! sister chromatid segregation GO:0000819 58 37 0,000 0,06312846 0,07682705 ! actomyosin structure organization GO:0031032 62 37 0,000 0,06312846 0,07678821 ! organic anion transport GO:0015711 68 37 0,000 0,06312846 0,07674941 ! tissue remodeling GO:0048771 76 37 0,000 0,06312846 0,07671064 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,06312846 0,07667192 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,06312846 0,07663324 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,06312846 0,07659459 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,06312846 0,07655599 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,06312846 0,07651742 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,06312846 0,07647889 ! pigment metabolic process GO:0042440 80 37 0,000 0,06312846 0,0764404 ! spermatid differentiation GO:0048515 66 37 0,000 0,06312846 0,07640195 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,06312846 0,07636354 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,0647792 0,07832098 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,0647792 0,07828164 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,0647792 0,07824234 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,0647792 0,07820309 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,0647792 0,07816387 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,0647792 0,07812469 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,0647792 0,07808555 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,0647792 0,07804644 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,0647792 0,07800738 ! lipid homeostasis GO:0055088 67 38 0,000 0,0647792 0,07796836 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,0647792 0,07792937 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,0647792 0,07789043 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,0647792 0,07785152 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,0647792 0,07781266 ! mRNA catabolic process GO:0006402 71 39 0,000 0,06642708 0,07975227 ! mammary gland development GO:0030879 86 39 0,000 0,06642708 0,0797125 ! learning GO:0007612 77 39 0,000 0,06642708 0,07967276 ! ear morphogenesis GO:0042471 60 39 0,000 0,06642708 0,07963306 ! organic ether metabolic process GO:0018904 55 39 0,000 0,06642708 0,07959341 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,06642708 0,07955379 ! segmentation GO:0035282 67 39 0,000 0,06642708 0,07951421 ! ion transmembrane transport GO:0034220 66 39 0,000 0,06642708 0,07947467 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,06642708 0,07943517 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,06642708 0,07939571 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,06642708 0,07935629 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,06642708 0,0793169 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,06807212 0,08124083 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,06807212 0,08120055 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,06807212 0,08116031 ! feeding behavior GO:0007631 59 40 0,000 0,06807212 0,08112012 ! negative regulation of binding GO:0051100 72 40 0,000 0,06807212 0,08107996 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,06807212 0,08103984 ! mesenchymal cell development GO:0014031 87 40 0,000 0,06807212 0,08099976 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 0,000 0,06807212 0,08095972 ! cytokinesis GO:0000910 72 40 0,000 0,06807212 0,08091972 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06971431 0,08283093 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06971431 0,08279004 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06971431 0,0827492 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06971431 0,08270839 ! gliogenesis GO:0042063 88 41 0,000 0,06971431 0,08266763 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06971431 0,08262691 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06971431 0,08258623 ! T cell differentiation GO:0030217 81 41 0,000 0,06971431 0,08254558 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,06971431 0,08250498 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06971431 0,08246442 ! female gamete generation GO:0007292 61 41 0,000 0,06971431 0,08242389 ! polyol metabolic process GO:0019751 66 41 0,000 0,06971431 0,08238341 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06971431 0,08234297 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,07135366 0,08423793 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,07135366 0,08419662 ! regulation of tube size GO:0035150 71 42 0,000 0,07135366 0,08415535 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,07135366 0,08411411 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,07135366 0,08407292 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,07135366 0,08403177 ! neuron migration GO:0001764 79 42 0,000 0,07135366 0,08399066 ! regulation of protein secretion GO:0050708 71 42 0,000 0,07135366 0,08394959 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,07135366 0,08390856 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,07299018 0,08579109 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,07299018 0,0857492 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,07299018 0,08570735 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,07299018 0,08566554 ! glucose transport GO:0015758 65 43 0,000 0,07299018 0,08562378 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,07299018 0,08558205 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,07299018 0,08554036 ! neural tube development GO:0021915 77 43 0,000 0,07299018 0,08549872 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,07299018 0,08545711 ! striated muscle contraction GO:0006941 77 43 0,000 0,07299018 0,08541555 ! phagocytosis GO:0006909 90 43 0,000 0,07299018 0,08537402 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,07299018 0,08533254 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,07462386 0,08720011 ! hexose transport GO:0008645 67 44 0,000 0,07462386 0,08715778 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,07462386 0,08711549 ! male sex differentiation GO:0046661 76 44 0,000 0,07462386 0,08707324 ! double-strand break repair GO:0006302 81 44 0,000 0,07462386 0,08703103 ! B cell differentiation GO:0030183 107 44 0,000 0,07462386 0,08698886 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,07462386 0,08694674 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,07462386 0,08690466 ! developmental growth GO:0048589 82 44 0,000 0,07462386 0,08686261 ! maintenance of location in cell GO:0051651 97 44 0,000 0,07462386 0,08682061 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,07625473 0,08867514 ! glycolysis GO:0006096 65 45 0,000 0,07625473 0,08863231 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,07625473 0,08858951 ! leukocyte migration GO:0050900 68 45 0,000 0,07625473 0,08854675 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,07625473 0,08850404 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,07625473 0,08846137 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,07625473 0,08841873 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,07625473 0,08837614 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,07625473 0,08833359 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,07625473 0,08829108 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,07625473 0,08824862 ! cell growth GO:0016049 84 45 0,000 0,07625473 0,08820619 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,07788277 0,0900461 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,07788277 0,09000285 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,07788277 0,08995965 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,07788277 0,08991648 ! pigmentation GO:0043473 100 46 0,000 0,07788277 0,08987335 ! response to insulin stimulus GO:0032868 95 46 0,000 0,07788277 0,08983027 ! positive regulation of defense response GO:0031349 76 47 0,000 0,079508 0,09166087 ! response to calcium ion GO:0051592 81 47 0,000 0,079508 0,09161697 ! endosome transport GO:0016197 108 47 0,000 0,079508 0,09157312 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,079508 0,0915293 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,079508 0,09148553 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,079508 0,0914418 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,079508 0,09139811 ! JNK cascade GO:0007254 91 47 0,000 0,079508 0,09135446 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,079508 0,09131085 ! protein homooligomerization GO:0051260 76 47 0,000 0,079508 0,09126729 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,08113041 0,09308525 ! mitochondrial transport GO:0006839 82 48 0,000 0,08113041 0,09304088 ! Notch signaling pathway GO:0007219 96 48 0,000 0,08113041 0,09299656 ! cellular component disassembly GO:0022411 86 48 0,000 0,08113041 0,09295227 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,08113041 0,09290803 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,08113041 0,09286383 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,08113041 0,09281967 ! activation of caspase activity GO:0006919 84 48 0,000 0,08113041 0,09277556 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,08113041 0,09273149 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,08113041 0,09268745 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,08113041 0,09264346 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,08275003 0,09444808 ! regulation of action potential GO:0001508 95 49 0,000 0,08275003 0,0944033 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,08275003 0,09435856 ! regulation of ion transport GO:0043269 77 49 0,000 0,08275003 0,09431386 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,08275003 0,0942692 ! peptide metabolic process GO:0006518 76 49 0,000 0,08275003 0,09422459 ! response to temperature stimulus GO:0009266 76 49 0,000 0,08275003 0,09418002 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,08275003 0,09413549 ! endocrine system development GO:0035270 104 49 0,000 0,08275003 0,094091 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,08275003 0,09404656 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,08275003 0,09400215 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,08275003 0,09395779 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,08275003 0,09391347 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,08436684 0,09570326 ! neuromuscular process GO:0050905 99 50 0,000 0,08436684 0,09565816 ! regulation of ossification GO:0030278 117 50 0,000 0,08436684 0,0956131 ! inner ear development GO:0048839 79 50 0,000 0,08436684 0,09556808 ! histone modification GO:0016570 91 50 0,000 0,08436684 0,09552311 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,08436684 0,09547818 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,08436684 0,09543329 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,08436684 0,09538844 ! positive regulation of binding GO:0051099 78 51 0,000 0,08598085 0,09716765 ! viral infectious cycle GO:0019058 99 51 0,000 0,08598085 0,09712203 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,08598085 0,09707645 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,08598085 0,09703092 ! excretion GO:0007588 83 51 0,000 0,08598085 0,09698543 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,08598085 0,09693998 ! chromatin remodeling GO:0006338 109 51 0,000 0,08598085 0,09689458 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,08598085 0,09684922 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,08598085 0,09680389 ! vesicle organization GO:0016050 107 51 0,000 0,08598085 0,09675862 ! regulation of cell shape GO:0008360 125 51 0,000 0,08598085 0,09671338 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,08598085 0,09666819 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,08759207 0,09843369 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,08759207 0,09838773 ! membrane fusion GO:0006944 110 52 0,000 0,08759207 0,09834182 ! positive regulation of growth GO:0045927 90 52 0,000 0,08759207 0,09829595 ! covalent chromatin modification GO:0016569 101 52 0,000 0,08759207 0,09825013 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,08759207 0,09820435 ! cartilage development GO:0051216 90 52 0,000 0,08759207 0,0981586 ! synapse organization GO:0050808 85 52 0,000 0,08759207 0,09811291 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,08920051 0,09986804 ! RNA catabolic process GO:0006401 93 53 0,000 0,08920051 0,09982159 ! regulation of translational initiation GO:0006446 82 53 0,000 0,08920051 0,09977518 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,08920051 0,09972882 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,08920051 0,0996825 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,08920051 0,09963622 ! cell maturation GO:0048469 100 53 0,000 0,08920051 0,09958999 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,08920051 0,09954379 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,08920051 0,09949765 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,09080616 0,10124172 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,09080616 0,10119482 ! cell recognition GO:0008037 85 54 0,000 0,09080616 0,10114797 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,09080616 0,10110117 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,09080616 0,10105441 ! chloride transport GO:0006821 90 55 0,000 0,09240904 0,10279064 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,09240904 0,10274314 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,09240904 0,10269568 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,09240904 0,10264827 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,09240904 0,1026009 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,09240904 0,10255357 ! aging GO:0007568 103 55 0,000 0,09240904 0,10250629 ! gastrulation GO:0007369 112 55 0,000 0,09240904 0,10245905 ! heart morphogenesis GO:0003007 97 55 0,000 0,09240904 0,10241186 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,09240904 0,10236471 ! RNA elongation GO:0006354 79 55 0,000 0,09240904 0,1023176 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,09240904 0,10227054 ! regulation of actin filament length GO:0030832 105 56 0,000 0,09400914 0,10399356 ! sensory perception of smell GO:0007608 80 56 0,000 0,09400914 0,10394577 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,09400914 0,10389802 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,09400914 0,10385032 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,09400914 0,10380266 ! regulation of DNA replication GO:0006275 101 56 0,000 0,09400914 0,10375504 ! proton transport GO:0015992 94 56 0,000 0,09400914 0,10370747 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,09400914 0,10365994 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,09560648 0,10537297 ! muscle fiber development GO:0048747 112 57 0,000 0,09560648 0,10532472 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,09560648 0,10527651 ! lipid modification GO:0030258 97 57 0,000 0,09560648 0,10522836 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,09560648 0,10518024 ! maintenance of location GO:0051235 118 57 0,000 0,09560648 0,10513217 ! hydrogen transport GO:0006818 97 58 0,000 0,09720105 0,10683679 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,09720105 0,106788 ! regulation of endocytosis GO:0030100 91 58 0,000 0,09720105 0,10673926 ! adult behavior GO:0030534 99 58 0,000 0,09720105 0,10669057 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,09720105 0,10664192 ! positive regulation of secretion GO:0051047 95 59 0,000 0,09879286 0,10833894 ! regulation of cellular component size GO:0032535 109 59 0,000 0,09879286 0,10828958 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,09879286 0,10824027 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,09879286 0,108191 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,09879286 0,10814178 ! DNA catabolic process GO:0006308 86 59 0,000 0,09879286 0,1080926 ! establishment of organelle localization GO:0051656 109 59 0,000 0,09879286 0,10804347 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,10038192 0,10973145 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,10038192 0,10968161 ! regulation of heart contraction GO:0008016 110 60 0,000 0,10038192 0,10963183 ! camera-type eye development GO:0043010 116 60 0,000 0,10038192 0,10958208 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,10038192 0,10953239 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,10038192 0,10948273 ! kidney development GO:0001822 122 60 0,000 0,10038192 0,10943313 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,10196824 0,11111213 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,10196824 0,11106183 ! mesoderm development GO:0007498 119 61 0,000 0,10196824 0,11101157 ! tRNA processing GO:0008033 89 61 0,000 0,10196824 0,11096136 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,10196824 0,1109112 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,10196824 0,11086108 ! ear development GO:0043583 103 62 0,000 0,1035518 0,1125319 ! viral reproductive process GO:0022415 126 62 0,000 0,1035518 0,1124811 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,1035518 0,11243034 ! gonad development GO:0008406 98 62 0,000 0,1035518 0,11237963 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,1035518 0,11232896 ! regulation of mitosis GO:0007088 105 63 0,000 0,10513263 0,11399239 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,10513263 0,11394104 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,10513263 0,11388974 ! detection of external stimulus GO:0009581 91 63 0,000 0,10513263 0,11383848 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,10513263 0,11378727 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,10513263 0,11373611 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,10671072 0,11539146 ! cell redox homeostasis GO:0045454 102 64 0,000 0,10671072 0,11533962 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,10671072 0,11528783 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,10671072 0,11523608 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,10671072 0,11518439 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,10671072 0,11513273 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,10828608 0,11678006 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,10828608 0,11672774 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,10828608 0,11667547 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,10828608 0,11662324 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,10985872 0,11826402 ! actin filament organization GO:0007015 148 66 0,000 0,10985872 0,11821113 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,10985872 0,11815828 ! extracellular matrix organization GO:0030198 133 66 0,000 0,10985872 0,11810549 ! secondary metabolic process GO:0019748 116 66 0,000 0,10985872 0,11805274 ! developmental maturation GO:0021700 116 66 0,000 0,10985872 0,11800003 ! cell projection assembly GO:0030031 120 66 0,000 0,10985872 0,11794738 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,11142863 0,11957952 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,11142863 0,11952621 ! activation of MAPK activity GO:0000187 115 67 0,000 0,11142863 0,11947295 ! lung development GO:0030324 144 67 0,000 0,11142863 0,11941973 ! chromosome segregation GO:0007059 113 67 0,000 0,11142863 0,11936656 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,11142863 0,11931344 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,11142863 0,11926036 ! hexose catabolic process GO:0019320 104 67 0,000 0,11142863 0,11920733 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,11142863 0,11915435 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,11142863 0,11910142 ! adaptive immune response GO:0002250 119 67 0,000 0,11142863 0,11904853 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,11142863 0,11899569 ! amino acid transport GO:0006865 125 68 0,000 0,11299583 0,12061578 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,11299583 0,12056229 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,11299583 0,12050885 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,11299583 0,12045546 ! viral reproduction GO:0016032 134 68 0,000 0,11299583 0,12040211 ! regulation of lipase activity GO:0060191 130 68 0,000 0,11299583 0,12034881 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,11299583 0,12029556 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,11299583 0,12024236 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,11456032 0,12185328 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,11456032 0,12179943 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,11456032 0,12174564 ! urogenital system development GO:0001655 137 69 0,000 0,11456032 0,12169188 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,11456032 0,12163818 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,11456032 0,12158452 ! antigen processing and presentation GO:0019882 104 69 0,000 0,11456032 0,12153092 ! appendage morphogenesis GO:0035107 135 70 0,000 0,11612209 0,12313343 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,11612209 0,12307919 ! amine catabolic process GO:0009310 117 71 0,000 0,11768117 0,12467675 ! reproductive structure development GO:0048608 113 71 0,000 0,11768117 0,12462187 ! appendage development GO:0048736 136 71 0,000 0,11768117 0,12456704 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,11768117 0,12451226 ! B cell activation GO:0042113 160 71 0,000 0,11768117 0,12445753 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,11768117 0,12440285 ! regulation of immune effector process GO:0002697 137 71 0,000 0,11768117 0,12434822 ! acute inflammatory response GO:0002526 113 72 0,000 0,11923754 0,12593746 ! regulation of caspase activity GO:0043281 122 72 0,000 0,11923754 0,1258822 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,11923754 0,12582699 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,11923754 0,12577183 ! carbohydrate transport GO:0008643 110 72 0,000 0,11923754 0,12571671 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,11923754 0,12566164 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,11923754 0,12560663 ! respiratory system development GO:0060541 153 72 0,000 0,11923754 0,12555166 ! learning or memory GO:0007611 147 73 0,000 0,12079123 0,12713197 ! regulation of blood pressure GO:0008217 125 73 0,000 0,12079123 0,12707639 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,12079123 0,12702085 ! axon guidance GO:0007411 139 73 0,000 0,12079123 0,12696535 ! fertilization GO:0009566 90 73 0,000 0,12079123 0,12690991 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,12234222 0,12848336 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,12234222 0,12842731 ! neurotransmitter transport GO:0006836 123 74 0,000 0,12234222 0,1283713 ! exocytosis GO:0006887 133 74 0,000 0,12234222 0,12831534 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,12234222 0,12825943 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,12234222 0,12820357 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,12234222 0,12814775 ! eye development GO:0001654 143 74 0,000 0,12234222 0,12809199 ! organelle localization GO:0051640 136 74 0,000 0,12234222 0,12803627 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,12389053 0,12960027 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,12389053 0,12954395 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,12389053 0,12948767 ! rhythmic process GO:0048511 128 75 0,000 0,12389053 0,12943145 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,12389053 0,12937527 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,12543616 0,1309325 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,12543616 0,13087572 ! defense response to bacterium GO:0042742 89 76 0,000 0,12543616 0,13081899 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,12543616 0,13076231 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,12543616 0,13070567 ! regulation of catabolic process GO:0009894 161 76 0,000 0,12543616 0,13064909 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,12697912 0,13219894 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,12697912 0,13214176 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,12697912 0,13208463 ! blood coagulation GO:0007596 146 78 0,000 0,1285194 0,13362907 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,1285194 0,13357135 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,1285194 0,13351368 ! protein oligomerization GO:0051259 139 78 0,000 0,1285194 0,13345605 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,13005702 0,13499447 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,13005702 0,13493626 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,13005702 0,13487809 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,13005702 0,13481998 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,13005702 0,13476192 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,13005702 0,13470391 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,13159197 0,13623506 ! response to metal ion GO:0010038 140 80 0,000 0,13159197 0,13617646 ! muscle cell differentiation GO:0042692 159 80 0,000 0,13159197 0,13611792 ! protein import into nucleus GO:0006606 158 80 0,000 0,13159197 0,13605942 ! inorganic anion transport GO:0015698 138 80 0,000 0,13159197 0,13600098 ! T cell activation GO:0042110 168 81 0,000 0,13312427 0,13752554 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,13312427 0,13746652 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,13312427 0,13740755 ! digestion GO:0007586 112 81 0,000 0,13312427 0,13734862 ! nuclear import GO:0051170 161 81 0,000 0,13312427 0,13728975 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,13312427 0,13723093 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,13465391 0,13874831 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,13465391 0,13868892 ! response to drug GO:0042493 143 82 0,000 0,13465391 0,13862957 ! response to nutrient GO:0007584 125 82 0,000 0,13465391 0,13857028 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,13465391 0,13851104 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,13465391 0,13845184 ! response to oxygen levels GO:0070482 176 83 0,000 0,13618091 0,1399621 ! regulation of lyase activity GO:0051339 160 83 0,000 0,13618091 0,13990233 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,13770526 0,14140796 ! hemostasis GO:0007599 158 84 0,000 0,13770526 0,14134764 ! negative regulation of transport GO:0051051 153 84 0,000 0,13770526 0,14128736 ! regulation of ligase activity GO:0051340 142 84 0,000 0,13770526 0,14122714 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,13770526 0,14116696 ! response to unfolded protein GO:0006986 131 85 0,000 0,13922698 0,14266614 ! nucleosome assembly GO:0006334 122 85 0,000 0,13922698 0,14260541 ! response to inorganic substance GO:0010035 153 86 0,000 0,14074605 0,1441 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,14074605 0,14403871 ! chromatin assembly GO:0031497 124 86 0,000 0,14074605 0,14397747 ! tube morphogenesis GO:0035239 176 86 0,000 0,14074605 0,14391628 ! mitochondrion organization GO:0007005 148 86 0,000 0,14074605 0,14385514 ! alcohol catabolic process GO:0046164 130 86 0,000 0,14074605 0,14379406 ! amine transport GO:0015837 155 86 0,000 0,14074605 0,14373302 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,1422625 0,14522002 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,1422625 0,14515843 ! protein localization in nucleus GO:0034504 176 87 0,000 0,1422625 0,1450969 ! cellular respiration GO:0045333 135 88 0,000 0,14377632 0,14657874 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,14377632 0,14651666 ! regulation of DNA binding GO:0051101 155 88 0,000 0,14377632 0,14645463 ! gland development GO:0048732 206 88 0,000 0,14377632 0,14639265 ! regulation of neurological system process GO:0031644 148 88 0,000 0,14377632 0,14633073 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,14377632 0,14626885 ! cellular defense response GO:0006968 114 89 0,000 0,14528753 0,14774378 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,14528753 0,14768136 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,14528753 0,147619 ! ossification GO:0001503 188 90 0,000 0,14679611 0,14908883 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,14679611 0,14902592 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,14679611 0,14896307 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,14679611 0,14890027 ! bone development GO:0060348 189 91 0,000 0,14830208 0,15036444 ! sterol metabolic process GO:0016125 152 91 0,000 0,14830208 0,1503011 ! response to protein stimulus GO:0051789 149 91 0,000 0,14830208 0,15023781 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,14830208 0,15017458 ! regulation of defense response GO:0031347 149 92 0,000 0,14980544 0,15163311 ! nucleosome organization GO:0034728 138 92 0,000 0,14980544 0,15156934 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,14980544 0,15150563 ! vitamin metabolic process GO:0006766 139 92 0,000 0,14980544 0,15144197 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,1513062 0,15289489 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,1513062 0,1528307 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,1513062 0,15276657 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,1513062 0,15270249 ! regulation of membrane potential GO:0042391 164 93 0,000 0,1513062 0,15263846 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,1513062 0,15257449 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,15280437 0,15402065 ! female pregnancy GO:0007565 164 94 0,000 0,15280437 0,15395616 ! transcription initiation GO:0006352 153 94 0,000 0,15280437 0,15389171 ! regulation of T cell activation GO:0050863 158 94 0,000 0,15280437 0,15382732 ! forebrain development GO:0030900 188 95 0,000 0,15429993 0,15526794 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,15429993 0,15520302 ! leukocyte differentiation GO:0002521 202 96 0,000 0,15579291 0,15663925 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,15579291 0,15657382 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,15579291 0,15650845 ! detection of stimulus GO:0051606 151 96 0,000 0,15579291 0,15644313 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,1572833 0,15787385 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,1572833 0,15780801 ! protein ubiquitination GO:0016567 217 97 0,000 0,1572833 0,15774223 ! hormone metabolic process GO:0042445 157 97 0,000 0,1572833 0,1576765 ! response to virus GO:0009615 160 98 0,000 0,1587711 0,15910174 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1587711 0,1590355 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,1587711 0,15896932 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,16025633 0,16038966 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,16025633 0,16032297 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,16025633 0,16025633 GO:0060538|skeletal muscle organ development,