pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6832-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,206E-06 4,065E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 3,091E-06 2,848E-03 ! regulation of cell migration GO:0030334 71 71 4,000 3,704E-06 2,276E-03 ! regulation of locomotion GO:0040012 79 79 4,000 6,294E-06 2,9E-03 ! regulation of cell motion GO:0051270 79 79 4,000 6,294E-06 2,32E-03 ! cell cycle arrest GO:0007050 49 49 3,000 2,173E-05 6,676E-03 ! regulation of fibroblast proliferation GO:0048145 17 17 2,000 2,457E-05 6,468E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 3,485E-05 8,028E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 4,09E-05 8,376E-03 ! response to radiation GO:0009314 70 68 3,000 7,992E-05 0,01472867 ! memory GO:0007613 5 5 1,000 1,159E-04 0,01941678 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 1,159E-04 0,01779871 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to amine stimulus GO:0014075 5 5 1,000 1,159E-04 0,01642958 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! T cell lineage commitment GO:0002360 5 5 1,000 1,159E-04 0,01525604 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,159E-04 0,01423897 ! male genitalia development GO:0030539 5 5 1,000 1,159E-04 0,01334904 ! regulation of DNA replication GO:0006275 32 31 2,000 1,573E-04 0,01705 ! ER overload response GO:0006983 6 6 1,000 1,735E-04 0,01776078 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,735E-04 0,016826 GO:0070667|negative regulation of mast cell proliferation, ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,735E-04 0,0159847 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,735E-04 0,01522352 ! genitalia development GO:0048806 6 6 1,000 1,735E-04 0,01453155 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,735E-04 0,01389974 ! protein sumoylation GO:0016925 6 6 1,000 1,735E-04 0,01332058 ! regulation of embryonic development GO:0045995 6 6 1,000 1,735E-04 0,01278776 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 1,998E-04 0,01416396 ! regulation of protein catabolic process GO:0042176 35 34 2,000 2,079E-04 0,01419343 ! positive regulation of transferase activity GO:0051347 91 88 3,000 2,184E-04 0,01437532 GO:0033674|positive regulation of kinase activity, ! visual behavior GO:0007632 7 7 1,000 2,423E-04 0,01540061 GO:0008542|visual learning, ! startle response GO:0001964 7 7 1,000 2,423E-04 0,01488726 ! regulation of mRNA processing GO:0050684 7 7 1,000 2,423E-04 0,01440703 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,423E-04 0,01395681 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 2,423E-04 0,01353387 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,423E-04 0,01313582 ! response to gamma radiation GO:0010332 8 7 1,000 2,423E-04 0,01276051 ! dopamine metabolic process GO:0042417 7 7 1,000 2,423E-04 0,01240605 ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,423E-04 0,01207075 ! positive regulation of cell migration GO:0030335 36 36 2,000 2,47E-04 0,01197802 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 2,681E-04 0,01267163 ! response to drug GO:0042493 37 37 2,000 2,681E-04 0,01235484 ! negative regulation of kinase activity GO:0033673 38 38 2,000 2,905E-04 0,01305673 ! positive regulation of cell motion GO:0051272 39 39 2,000 3,14E-04 0,01377643 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 1,000 3,224E-04 0,01381911 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 3,224E-04 0,01350504 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 3,224E-04 0,01320492 ! actin filament polymerization GO:0030041 9 8 1,000 3,224E-04 0,01291786 ! negative regulation of transferase activity GO:0051348 40 40 2,000 3,386E-04 0,01327859 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 4,137E-04 0,01588274 ! regulation of postsynaptic membrane potential GO:0060078 9 9 1,000 4,137E-04 0,0155586 ! response to ethanol GO:0045471 9 9 1,000 4,137E-04 0,01524743 ! pigmentation during development GO:0048066 9 9 1,000 4,137E-04 0,01494846 ! regulation of cellular pH GO:0030641 9 9 1,000 4,137E-04 0,01466099 ! regulation of membrane potential GO:0042391 46 46 2,000 5,132E-04 0,01784528 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 5,16E-04 0,0176099 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 5,16E-04 0,01728972 ! centrosome cycle GO:0007098 10 10 1,000 5,16E-04 0,01698098 ! neuromuscular junction development GO:0007528 10 10 1,000 5,16E-04 0,01668306 ! cytolysis GO:0019835 10 10 1,000 5,16E-04 0,01639542 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 5,16E-04 0,01611754 ! regulation of catabolic process GO:0009894 48 47 2,000 5,469E-04 0,0167996 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 6,186E-04 0,01868958 ! activation of MAPKK activity GO:0000186 12 11 1,000 6,293E-04 0,0187061 ! cellular response to starvation GO:0009267 11 11 1,000 6,293E-04 0,01840918 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 6,293E-04 0,01812153 ! G1/S transition checkpoint GO:0031575 12 11 1,000 6,293E-04 0,01784274 ! membrane depolarization GO:0051899 11 11 1,000 6,293E-04 0,0175724 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 6,293E-04 0,01731012 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 6,566E-04 0,01779502 ! protein modification by small protein conjugation GO:0032446 52 51 2,000 6,96E-04 0,0185906 ! response to light stimulus GO:0009416 53 52 2,000 7,369E-04 0,01940251 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 7,535E-04 0,01956015 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 7,535E-04 0,01928848 ! glutamate signaling pathway GO:0007215 12 12 1,000 7,535E-04 0,01902425 ! microtubule organizing center organization GO:0031023 12 12 1,000 7,535E-04 0,01876717 GO:0051297|centrosome organization, ! regulation of chromosome organization GO:0033044 12 12 1,000 7,535E-04 0,01851694 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 7,535E-04 0,01827329 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 7,535E-04 0,01803598 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 8,688E-04 0,02052905 ! regulation of cell adhesion GO:0030155 56 55 2,000 8,688E-04 0,02026918 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 8,688E-04 0,02001582 ! positive regulation of DNA replication GO:0045740 14 13 1,000 8,886E-04 0,0202195 ! phenol metabolic process GO:0018958 13 13 1,000 8,886E-04 0,01997292 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 8,886E-04 0,01973229 ! mitochondrial membrane organization GO:0007006 13 13 1,000 8,886E-04 0,01949738 ! negative regulation of DNA replication GO:0008156 13 13 1,000 8,886E-04 0,019268 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 8,886E-04 0,01904395 ! cell aging GO:0007569 13 13 1,000 8,886E-04 0,01882505 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 8,886E-04 0,01861113 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 8,886E-04 0,01840202 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 8,886E-04 0,01819755 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 8,886E-04 0,01799758 ! tissue homeostasis GO:0001894 13 13 1,000 8,886E-04 0,01780195 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 8,886E-04 0,01761054 ! extracellular structure organization GO:0043062 56 56 2,000 9,159E-04 0,01795784 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 1,035E-03 0,02007027 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 1,035E-03 0,01986121 ! actin polymerization or depolymerization GO:0008154 15 14 1,000 1,035E-03 0,01965645 ! base-excision repair GO:0006284 14 14 1,000 1,035E-03 0,01945587 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 1,067E-03 0,01985986 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,191E-03 0,02195328 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 1,191E-03 0,02173592 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 1,191E-03 0,02152282 ! complement activation, classical pathway GO:0006958 15 15 1,000 1,191E-03 0,02131387 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,191E-03 0,02110892 ! response to starvation GO:0042594 15 15 1,000 1,191E-03 0,02090789 ! response to ionizing radiation GO:0010212 16 15 1,000 1,191E-03 0,02071064 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,191E-03 0,02051709 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 1,358E-03 0,02318155 ! learning GO:0007612 16 16 1,000 1,358E-03 0,02296888 ! positive regulation of mitosis GO:0045840 16 16 1,000 1,358E-03 0,02276007 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,358E-03 0,02255502 ! iron ion homeostasis GO:0055072 16 16 1,000 1,358E-03 0,02235364 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,358E-03 0,02215582 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,358E-03 0,02196147 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 1,478E-03 0,02368331 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,536E-03 0,02440849 ! myelination GO:0042552 17 17 1,000 1,536E-03 0,02419987 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 1,536E-03 0,02399479 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 1,000 1,536E-03 0,02379315 ! negative regulation of cell development GO:0010721 18 17 1,000 1,536E-03 0,02359487 GO:0050768|negative regulation of neurogenesis, ! pigmentation GO:0043473 17 17 1,000 1,536E-03 0,02339987 ! Ras protein signal transduction GO:0007265 69 67 2,000 1,544E-03 0,0233175 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 1,68E-03 0,02517974 ! meiosis I GO:0007127 18 18 1,000 1,725E-03 0,02563332 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 1,725E-03 0,02542825 ! B cell differentiation GO:0030183 18 18 1,000 1,725E-03 0,02522644 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 1,725E-03 0,02502781 ! ensheathment of neurons GO:0007272 18 18 1,000 1,725E-03 0,02483228 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 1,725E-03 0,02463978 ! DNA damage checkpoint GO:0000077 19 19 1,000 1,923E-03 0,02726862 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 1,000 1,923E-03 0,02706046 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 1,923E-03 0,02685546 ! regulation of pH GO:0006885 19 19 1,000 1,923E-03 0,02665354 ! peripheral nervous system development GO:0007422 19 19 1,000 1,923E-03 0,02645463 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,133E-03 0,02911426 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 2,352E-03 0,03187439 ! mammary gland development GO:0030879 23 21 1,000 2,352E-03 0,03164173 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,352E-03 0,03141244 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,352E-03 0,03118645 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,352E-03 0,03096369 ! negative regulation of protein transport GO:0051224 21 21 1,000 2,352E-03 0,03074409 ! nuclear transport GO:0051169 79 79 2,000 2,479E-03 0,03217504 GO:0006913|nucleocytoplasmic transport, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 2,582E-03 0,03327462 ! sister chromatid segregation GO:0000819 22 22 1,000 2,582E-03 0,03304355 ! odontogenesis GO:0042476 22 22 1,000 2,582E-03 0,03281566 ! spindle organization GO:0007051 22 22 1,000 2,582E-03 0,0325909 ! male sex differentiation GO:0046661 22 22 1,000 2,582E-03 0,03236919 ! cytokinesis GO:0000910 23 22 1,000 2,582E-03 0,03215048 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 2,822E-03 0,03490176 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 2,822E-03 0,03466908 ! mitochondrial transport GO:0006839 24 24 1,000 3,072E-03 0,0374905 ! regulation of action potential GO:0001508 24 24 1,000 3,072E-03 0,03724386 ! T cell differentiation GO:0030217 24 24 1,000 3,072E-03 0,03700043 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 3,332E-03 0,0398718 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 3,332E-03 0,03961457 ! regulation of T cell proliferation GO:0042129 25 25 1,000 3,332E-03 0,03936063 ! negative regulation of immune system process GO:0002683 25 25 1,000 3,332E-03 0,03910992 ! negative regulation of cell migration GO:0030336 26 26 1,000 3,602E-03 0,04201148 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 3,602E-03 0,04174726 ! regulation of T cell differentiation GO:0045580 26 26 1,000 3,602E-03 0,04148634 ! double-strand break repair GO:0006302 27 26 1,000 3,602E-03 0,04122866 ! synapse organization GO:0050808 26 26 1,000 3,602E-03 0,04097416 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 3,882E-03 0,04388718 ! learning or memory GO:0007611 28 27 1,000 3,882E-03 0,04361958 ! activation of caspase activity GO:0006919 27 27 1,000 3,882E-03 0,04335522 ! neuromuscular process GO:0050905 28 28 1,000 4,171E-03 0,0463104 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 4,171E-03 0,0460331 ! positive regulation of cell cycle GO:0045787 29 29 1,000 4,471E-03 0,04904429 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 4,471E-03 0,04875408 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 4,471E-03 0,04846729 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! response to UV GO:0009411 29 29 1,000 4,471E-03 0,04818386 ! endocytosis GO:0006897 99 98 2,000 4,565E-03 0,04891979 GO:0010324|membrane invagination, ! positive regulation of peptidase activity GO:0010952 30 30 1,000 4,78E-03 0,0509204 GO:0043280|positive regulation of caspase activity, ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 4,78E-03 0,05062775 GO:0019724|B cell mediated immunity, ! establishment of organelle localization GO:0051656 31 30 1,000 4,78E-03 0,05033845 ! hemopoiesis GO:0030097 104 100 2,000 4,832E-03 0,0505952 ! skeletal muscle fiber development GO:0048741 31 31 1,000 5,099E-03 0,05308911 ! B cell activation GO:0042113 31 31 1,000 5,099E-03 0,05279085 ! aging GO:0007568 32 31 1,000 5,099E-03 0,05249593 ! extracellular matrix organization GO:0030198 31 31 1,000 5,099E-03 0,05220429 ! regulation of intracellular transport GO:0032386 31 31 1,000 5,099E-03 0,05191587 ! negative regulation of cell motion GO:0051271 31 31 1,000 5,099E-03 0,05163062 ! negative regulation of cell growth GO:0030308 32 32 1,000 5,427E-03 0,05465546 ! muscle fiber development GO:0048747 32 32 1,000 5,427E-03 0,05435842 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 5,427E-03 0,05406459 ! nuclear export GO:0051168 32 32 1,000 5,427E-03 0,05377392 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 5,427E-03 0,05348636 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 5,427E-03 0,05320186 ! negative regulation of cell size GO:0045792 33 33 1,000 5,765E-03 0,05621504 ! activation of protein kinase activity GO:0032147 35 33 1,000 5,765E-03 0,05591917 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 5,765E-03 0,0556264 ! regulation of synaptic transmission GO:0050804 33 33 1,000 5,765E-03 0,05533668 ! regulation of angiogenesis GO:0045765 35 34 1,000 6,112E-03 0,05836648 ! acute inflammatory response GO:0002526 35 35 1,000 6,469E-03 0,06145411 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 6,469E-03 0,06113896 ! regulation of mitosis GO:0007088 37 36 1,000 6,835E-03 0,06426849 GO:0051783|regulation of nuclear division, ! positive regulation of organelle organization GO:0010638 36 36 1,000 6,835E-03 0,06394225 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 6,835E-03 0,06361931 ! activation of immune response GO:0002253 36 36 1,000 6,835E-03 0,06329961 ! meiosis GO:0007126 37 37 1,000 7,21E-03 0,06644095 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 1,000 7,21E-03 0,0661104 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 7,21E-03 0,06578312 ! negative regulation of growth GO:0045926 37 37 1,000 7,21E-03 0,06545907 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 7,21E-03 0,06513819 ! adaptive immune response GO:0002250 37 37 1,000 7,21E-03 0,06482044 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! chromosome segregation GO:0007059 38 38 1,000 7,595E-03 0,06794506 ! meiotic cell cycle GO:0051321 38 38 1,000 7,595E-03 0,06761683 ! axon guidance GO:0007411 39 38 1,000 7,595E-03 0,06729174 ! regulation of neurological system process GO:0031644 38 38 1,000 7,595E-03 0,06696977 ! nucleotide-excision repair GO:0006289 40 39 1,000 7,988E-03 0,07010469 ! respiratory system development GO:0060541 40 39 1,000 7,988E-03 0,06977244 ! lymphocyte differentiation GO:0030098 39 39 1,000 7,988E-03 0,06944332 ! protein oligomerization GO:0051259 39 39 1,000 7,988E-03 0,0691173 ! respiratory tube development GO:0030323 40 39 1,000 7,988E-03 0,06879432 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 7,988E-03 0,06847435 ! organelle localization GO:0051640 41 40 1,000 8,391E-03 0,07159249 ! cell cycle checkpoint GO:0000075 42 41 1,000 8,802E-03 0,0747583 ! regulation of caspase activity GO:0043281 41 41 1,000 8,802E-03 0,07441537 ! leukocyte mediated immunity GO:0002443 41 41 1,000 8,802E-03 0,07407557 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 9,223E-03 0,07726175 ! development of primary sexual characteristics GO:0045137 42 42 1,000 9,223E-03 0,07691215 ! protein ubiquitination GO:0016567 43 42 1,000 9,223E-03 0,0765657 ! mitochondrion organization GO:0007005 44 43 1,000 9,652E-03 0,07977116 ! humoral immune response GO:0006959 44 44 1,000 0,01009039 0,08302049 ! protein import into nucleus GO:0006606 44 44 1,000 0,01009039 0,08265151 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,01009039 0,08228579 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01053735 0,08555212 ! nuclear import GO:0051170 45 45 1,000 0,01053735 0,08517689 ! protein processing GO:0016485 45 45 1,000 0,01053735 0,08480494 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01099299 0,08808731 ! sex differentiation GO:0007548 47 47 1,000 0,01145726 0,09141009 ! calcium ion transport GO:0006816 48 48 1,000 0,0119301 0,09477227 ! actin filament organization GO:0007015 50 48 1,000 0,0119301 0,09436552 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,0119301 0,09396225 ! protein localization in nucleus GO:0034504 48 48 1,000 0,0119301 0,09356241 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01241144 0,0969249 ! gland development GO:0048732 51 49 1,000 0,01241144 0,09651594 ! divalent metal ion transport GO:0070838 49 49 1,000 0,01241144 0,09611041 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01241144 0,09570827 GO:0060538|skeletal muscle organ development, ! negative regulation of transport GO:0051051 51 50 1,000 0,01290122 0,09907064 ! T cell activation GO:0042110 51 50 1,000 0,01290122 0,09865956 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,01290122 0,09825187 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01290122 0,09784754 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01290122 0,09744653 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,01339939 0,10079626 ! positive regulation of immune response GO:0050778 51 51 1,000 0,01339939 0,10038652 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01339939 0,0999801 GO:0051325|interphase, ! protein maturation GO:0051604 51 51 1,000 0,01339939 0,09957695 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,01390589 0,10292594 ! cell fate commitment GO:0045165 52 52 1,000 0,01390589 0,10251424 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01442066 0,10588555 ! regulation of protein transport GO:0051223 53 53 1,000 0,01442066 0,10546537 GO:0070201|regulation of establishment of protein localization, ! in utero embryonic development GO:0001701 55 55 1,000 0,01547476 0,11272718 ! reproductive developmental process GO:0003006 56 56 1,000 0,01601397 0,11619588 ! regulation of nervous system development GO:0051960 57 56 1,000 0,01601397 0,11574021 ! regulation of protein localization GO:0032880 58 57 1,000 0,01656122 0,11922787 ! innate immune response GO:0045087 58 58 1,000 0,01711645 0,12274559 ! rRNA transcription GO:0009303 5 5 0,000 0,0173256 0,12376387 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0173256 0,12328602 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0173256 0,12281184 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0173256 0,1223413 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0173256 0,12187435 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0173256 0,12141095 ! reproductive cellular process GO:0048610 5 5 0,000 0,0173256 0,12095106 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,0173256 0,12049464 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0173256 0,12004165 ! prostate gland development GO:0030850 5 5 0,000 0,0173256 0,11959206 ! metencephalon development GO:0022037 5 5 0,000 0,0173256 0,11914582 ! water transport GO:0006833 5 5 0,000 0,0173256 0,1187029 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0173256 0,11826325 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0173256 0,11782686 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0173256 0,11739367 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0173256 0,11696366 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0173256 0,11653678 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0173256 0,11611301 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0173256 0,11569231 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0173256 0,11527465 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0173256 0,11486 ! filopodium assembly GO:0046847 7 5 0,000 0,0173256 0,11444831 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0173256 0,11403957 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0173256 0,11363373 ! GTP metabolic process GO:0046039 5 5 0,000 0,0173256 0,11323078 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0173256 0,11283067 ! mRNA stabilization GO:0048255 5 5 0,000 0,0173256 0,11243338 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0173256 0,11203887 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0173256 0,11164713 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0173256 0,11125811 ! social behavior GO:0035176 5 5 0,000 0,0173256 0,1108718 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0173256 0,11048816 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0173256 0,11010717 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0173256 0,10972879 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0173256 0,10935301 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0173256 0,10897979 ! response to lipid GO:0033993 5 5 0,000 0,0173256 0,10860911 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0173256 0,10824095 ! hippocampus development GO:0021766 6 5 0,000 0,0173256 0,10787527 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0173256 0,10751205 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0173256 0,10715127 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0173256 0,10679291 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0173256 0,10643693 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0173256 0,10608332 ! heart looping GO:0001947 5 5 0,000 0,0173256 0,10573205 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0173256 0,1053831 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0173256 0,10503644 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0173256 0,10469206 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0173256 0,10434993 ! pH reduction GO:0045851 5 5 0,000 0,0173256 0,10401003 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0173256 0,10367233 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0173256 0,10333682 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0173256 0,10300348 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0173256 0,10267228 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0173256 0,1023432 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0173256 0,10201623 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0173256 0,10169133 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0173256 0,1013685 ! adrenal gland development GO:0030325 5 5 0,000 0,0173256 0,10104772 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0173256 0,10072896 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0173256 0,1004122 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0173256 0,10009743 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0173256 0,09978462 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0173256 0,09947377 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0173256 0,09916484 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0173256 0,09885783 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0173256 0,09855271 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0173256 0,09824947 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0173256 0,09794809 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0173256 0,09764856 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0173256 0,09735085 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0173256 0,09705495 ! muscle cell migration GO:0014812 5 5 0,000 0,0173256 0,09676084 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0173256 0,09646852 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0173256 0,09617795 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0173256 0,09588913 ! response to ATP GO:0033198 5 5 0,000 0,0173256 0,09560203 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0173256 0,09531665 ! regulation of appetite GO:0032098 5 5 0,000 0,0173256 0,09503297 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0173256 0,09475098 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0173256 0,09447065 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,0173256 0,09419197 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0173256 0,09391494 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0173256 0,09363953 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0173256 0,09336573 ! receptor clustering GO:0043113 5 5 0,000 0,0173256 0,09309352 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0173256 0,0928229 ! fear response GO:0042596 5 5 0,000 0,0173256 0,09255385 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0173256 0,09228635 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0173256 0,0920204 ! retinol metabolic process GO:0042572 5 5 0,000 0,0173256 0,09175597 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0173256 0,09149306 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0173256 0,09123165 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0173256 0,09097173 ! parturition GO:0007567 5 5 0,000 0,0173256 0,09071329 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0173256 0,09045631 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0173256 0,09020079 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0173256 0,0899467 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0173256 0,08969404 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0173256 0,0894428 ! protein heterooligomerization GO:0051291 5 5 0,000 0,0173256 0,08919296 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0173256 0,08894451 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0173256 0,08869744 ! response to UV-B GO:0010224 5 5 0,000 0,0173256 0,08845174 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0173256 0,0882074 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0173256 0,0879644 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0173256 0,08772274 ! interaction with symbiont GO:0051702 5 5 0,000 0,0173256 0,08748241 ! cellular extravasation GO:0045123 5 5 0,000 0,0173256 0,08724338 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0173256 0,08700566 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0173256 0,08676924 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0173256 0,08653409 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0173256 0,08630021 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0173256 0,0860676 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0173256 0,08583623 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0173256 0,08560611 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0173256 0,08537722 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0173256 0,08514954 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0173256 0,08492308 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0173256 0,08469782 ! neuron recognition GO:0008038 5 5 0,000 0,0173256 0,08447375 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,0173256 0,08425087 ! decidualization GO:0046697 5 5 0,000 0,0173256 0,08402915 ! hair follicle maturation GO:0048820 5 5 0,000 0,0173256 0,08380861 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0173256 0,08358921 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0173256 0,08337096 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0173256 0,08315385 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0173256 0,08293787 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0173256 0,082723 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0173256 0,08250925 ! postreplication repair GO:0006301 5 5 0,000 0,0173256 0,08229659 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0173256 0,08208504 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0173256 0,08187456 ! histone methylation GO:0016571 5 5 0,000 0,0173256 0,08166516 ! DNA methylation GO:0006306 5 5 0,000 0,0173256 0,08145683 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0173256 0,08124956 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0173256 0,08104335 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0173256 0,08083817 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0173256 0,08063404 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0173256 0,08043093 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0173256 0,08022884 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0173256 0,08002777 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0173256 0,0798277 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0173256 0,07962863 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0173256 0,07943054 ! sterol catabolic process GO:0016127 5 5 0,000 0,0173256 0,07923345 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0173256 0,07903732 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0173256 0,07884217 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0173256 0,07864798 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0173256 0,07845474 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0173256 0,07826245 ! zymogen activation GO:0031638 5 5 0,000 0,0173256 0,0780711 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0173256 0,07788068 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0173256 0,07769119 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0173256 0,07750262 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,0173256 0,07731496 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0173256 0,07712821 ! nucleosome positioning GO:0016584 5 5 0,000 0,0173256 0,07694236 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0173256 0,0767574 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0173256 0,07657333 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0173256 0,07639014 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0173256 0,07620783 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0173256 0,07602638 ! NADPH regeneration GO:0006740 5 5 0,000 0,0173256 0,07584579 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0173256 0,07566606 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0173256 0,07548718 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0173256 0,07530915 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0173256 0,07513195 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0173256 0,07495558 ! sarcomere organization GO:0045214 5 5 0,000 0,0173256 0,07478004 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0173256 0,07460532 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0173256 0,07443142 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0173256 0,07425832 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0173256 0,07408603 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0173256 0,07391453 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0173256 0,07374383 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0173256 0,07357391 ! spleen development GO:0048536 5 5 0,000 0,0173256 0,07340478 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0173256 0,07323642 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0173256 0,07306883 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0173256 0,07290201 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0173256 0,07273594 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0173256 0,07257063 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0173256 0,07240607 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0173256 0,07224226 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0173256 0,07207918 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0173256 0,07191684 ! ATP catabolic process GO:0006200 5 5 0,000 0,0173256 0,07175523 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0173256 0,07159435 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0173256 0,07143418 ! blastocyst formation GO:0001825 5 5 0,000 0,0173256 0,07127473 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0173256 0,07111599 ! embryonic gut development GO:0048566 5 5 0,000 0,0173256 0,07095795 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0173256 0,07080062 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0173256 0,07064398 ! activation of innate immune response GO:0002218 5 5 0,000 0,0173256 0,07048803 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,0173256 0,07033277 ! catecholamine transport GO:0051937 5 5 0,000 0,0173256 0,0701782 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0173256 0,0700243 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0173256 0,06987107 ! muscle adaptation GO:0043500 5 5 0,000 0,0173256 0,06971851 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0173256 0,06956662 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0173256 0,06941539 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0173256 0,06926481 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0173256 0,06911489 ! defense response to fungus GO:0050832 5 5 0,000 0,0173256 0,06896561 ! lysogeny GO:0030069 5 5 0,000 0,0173256 0,06881698 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0173256 0,06866899 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0173256 0,06852163 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0173256 0,0683749 ! response to nicotine GO:0035094 5 5 0,000 0,0173256 0,0682288 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0173256 0,06808332 ! mitochondrion localization GO:0051646 5 5 0,000 0,0173256 0,06793847 ! nucleus localization GO:0051647 5 5 0,000 0,0173256 0,06779422 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0173256 0,06765059 ! regulation of cell development GO:0060284 60 59 1,000 0,0176796 0,06888688 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,0176796 0,06874155 ! protein localization in organelle GO:0033365 59 59 1,000 0,0176796 0,06859683 ! immune effector process GO:0002252 59 59 1,000 0,0176796 0,06845272 ! protein polymerization GO:0051258 65 60 1,000 0,0182506 0,07051543 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,01882941 0,0725996 ! axonogenesis GO:0007409 66 62 1,000 0,01941597 0,07470489 ! protein import GO:0017038 62 62 1,000 0,01941597 0,07454925 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,01941597 0,07439426 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,01941597 0,07423992 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,02001023 0,07635372 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,02061212 0,07848787 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02075603 0,0788729 ! axon extension GO:0048675 7 6 0,000 0,02075603 0,07871061 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02075603 0,07854899 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,02075603 0,07838802 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,02075603 0,07822772 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02075603 0,07806807 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02075603 0,07790907 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02075603 0,07775072 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02075603 0,07759301 ! virus-host interaction GO:0019048 6 6 0,000 0,02075603 0,07743594 ! regulation of S phase GO:0033261 6 6 0,000 0,02075603 0,07727951 ! myotube differentiation GO:0014902 6 6 0,000 0,02075603 0,0771237 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02075603 0,07696852 ! bone remodeling GO:0046849 6 6 0,000 0,02075603 0,07681397 ! N-glycan processing GO:0006491 6 6 0,000 0,02075603 0,07666003 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02075603 0,07650671 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02075603 0,076354 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02075603 0,0762019 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02075603 0,07605041 ! RNA methylation GO:0001510 6 6 0,000 0,02075603 0,07589952 ! cartilage condensation GO:0001502 7 6 0,000 0,02075603 0,07574922 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02075603 0,07559952 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02075603 0,07545041 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02075603 0,07530188 ! artery development GO:0060840 6 6 0,000 0,02075603 0,07515394 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02075603 0,07500658 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02075603 0,0748598 ! androgen metabolic process GO:0008209 6 6 0,000 0,02075603 0,07471359 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02075603 0,07456794 ! limbic system development GO:0021761 7 6 0,000 0,02075603 0,07442287 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02075603 0,07427836 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02075603 0,07413441 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02075603 0,07399102 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02075603 0,07384818 ! pathogenesis GO:0009405 6 6 0,000 0,02075603 0,07370589 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02075603 0,07356415 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02075603 0,07342295 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02075603 0,07328229 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02075603 0,07314217 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02075603 0,07300259 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02075603 0,07286353 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02075603 0,07272501 ! arginine metabolic process GO:0006525 6 6 0,000 0,02075603 0,07258701 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02075603 0,07244954 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02075603 0,07231258 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02075603 0,07217614 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02075603 0,07204022 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02075603 0,0719048 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02075603 0,0717699 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02075603 0,0716355 ! V(D)J recombination GO:0033151 6 6 0,000 0,02075603 0,0715016 ! focal adhesion formation GO:0048041 7 6 0,000 0,02075603 0,0713682 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02075603 0,0712353 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02075603 0,07110289 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02075603 0,07097098 ! regulation of heart rate GO:0002027 6 6 0,000 0,02075603 0,07083955 ! lipid digestion GO:0044241 6 6 0,000 0,02075603 0,07070861 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02075603 0,07057815 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02075603 0,07044817 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02075603 0,07031867 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02075603 0,07018964 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02075603 0,07006109 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02075603 0,06993301 ! ruffle organization GO:0031529 6 6 0,000 0,02075603 0,06980539 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02075603 0,06967824 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02075603 0,06955156 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02075603 0,06942533 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02075603 0,06929956 ! L-amino acid transport GO:0015807 6 6 0,000 0,02075603 0,06917424 ! bone mineralization GO:0030282 6 6 0,000 0,02075603 0,06904938 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02075603 0,06892497 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02075603 0,068801 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02075603 0,06867748 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02075603 0,0685544 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02075603 0,06843176 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02075603 0,06830956 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02075603 0,0681878 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02075603 0,06806647 ! regulation of organ growth GO:0046620 6 6 0,000 0,02075603 0,06794557 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02075603 0,0678251 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02075603 0,06770505 ! response to dsRNA GO:0043331 6 6 0,000 0,02075603 0,06758543 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02075603 0,06746624 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02075603 0,06734746 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02075603 0,0672291 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02075603 0,06711115 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02075603 0,06699362 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02075603 0,0668765 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02075603 0,06675978 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02075603 0,06664348 ! erythrocyte development GO:0048821 6 6 0,000 0,02075603 0,06652758 ! renal water homeostasis GO:0003091 6 6 0,000 0,02075603 0,06641208 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02075603 0,06629698 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02075603 0,06618228 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02075603 0,06606797 ! ribosome assembly GO:0042255 6 6 0,000 0,02075603 0,06595406 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02075603 0,06584054 ! diencephalon development GO:0021536 6 6 0,000 0,02075603 0,06572742 ! fucose catabolic process GO:0019317 6 6 0,000 0,02075603 0,06561468 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02075603 0,06550232 GO:0006809|nitric oxide biosynthetic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,02075603 0,06539035 ! regulation of cell division GO:0051302 6 6 0,000 0,02075603 0,06527876 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02075603 0,06516756 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02075603 0,06505673 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02075603 0,06494627 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02075603 0,0648362 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02075603 0,06472649 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02075603 0,06461716 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02075603 0,06450819 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02075603 0,06439959 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02075603 0,06429135 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02075603 0,06418348 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02075603 0,06407597 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02075603 0,06396882 ! thymus development GO:0048538 6 6 0,000 0,02075603 0,06386203 ! lymph node development GO:0048535 6 6 0,000 0,02075603 0,06375559 ! organic cation transport GO:0015695 6 6 0,000 0,02075603 0,06364951 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02075603 0,06354378 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02075603 0,0634384 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,02075603 0,06333337 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02075603 0,06322869 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02075603 0,06312435 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02075603 0,06302036 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02075603 0,0629167 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02075603 0,06281339 ! alditol metabolic process GO:0019400 6 6 0,000 0,02075603 0,06271042 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02075603 0,06260778 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02075603 0,06250548 ! maternal placenta development GO:0001893 6 6 0,000 0,02075603 0,06240352 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02075603 0,06230188 ! localization within membrane GO:0051668 6 6 0,000 0,02075603 0,06220058 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,02122158 0,0634925 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,02183858 0,06523257 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,02246304 0,06698929 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,02246304 0,06688107 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,02246304 0,0667732 ! regulation of cell size GO:0008361 68 68 1,000 0,02309492 0,06854095 ! response to nutrient levels GO:0031667 69 69 1,000 0,02373415 0,07032483 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02373415 0,07021195 ! respiratory burst GO:0045730 7 7 0,000 0,02417497 0,07140141 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02417497 0,07128717 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02417497 0,07117329 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02417497 0,07105977 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02417497 0,07094662 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02417497 0,07083383 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02417497 0,07072139 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02417497 0,07060932 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02417497 0,07049759 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02417497 0,07038622 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02417497 0,0702752 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02417497 0,07016453 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02417497 0,07005421 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02417497 0,06994424 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02417497 0,06983461 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02417497 0,06972532 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02417497 0,06961637 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02417497 0,06950777 ! axis specification GO:0009798 7 7 0,000 0,02417497 0,0693995 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02417497 0,06929157 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02417497 0,06918397 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02417497 0,06907671 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02417497 0,06896978 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02417497 0,06886318 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02417497 0,06875691 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02417497 0,06865097 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02417497 0,06854535 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02417497 0,06844006 ! digestive system development GO:0055123 7 7 0,000 0,02417497 0,06833509 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02417497 0,06823044 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02417497 0,06812611 ! protein targeting to ER GO:0045047 8 7 0,000 0,02417497 0,0680221 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02417497 0,06791841 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02417497 0,06781504 ! endoderm development GO:0007492 7 7 0,000 0,02417497 0,06771197 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02417497 0,06760922 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02417497 0,06750679 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,02417497 0,06740466 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02417497 0,06730284 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02417497 0,06720133 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02417497 0,06710012 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02417497 0,06699922 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02417497 0,06689862 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02417497 0,06679832 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02417497 0,06669832 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02417497 0,06659862 ! UV protection GO:0009650 7 7 0,000 0,02417497 0,06649922 ! DNA integration GO:0015074 7 7 0,000 0,02417497 0,06640012 ! myofibril assembly GO:0030239 7 7 0,000 0,02417497 0,06630131 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02417497 0,06620279 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02417497 0,06610457 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02417497 0,06600664 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02417497 0,06590899 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02417497 0,06581164 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02417497 0,06571457 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02417497 0,06561779 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02417497 0,06552129 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02417497 0,06542508 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02417497 0,06532915 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02417497 0,0652335 ! axon cargo transport GO:0008088 7 7 0,000 0,02417497 0,06513813 ! eating behavior GO:0042755 7 7 0,000 0,02417497 0,06504303 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02417497 0,06494822 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02417497 0,06485368 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02417497 0,06475942 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02417497 0,06466543 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02417497 0,06457171 ! cranial nerve development GO:0021545 7 7 0,000 0,02417497 0,06447826 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02417497 0,06438508 ! induction of an organ GO:0001759 7 7 0,000 0,02417497 0,06429218 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02417497 0,06419954 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02417497 0,06410716 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02417497 0,06401506 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02417497 0,06392321 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02417497 0,06383163 ! platelet activation GO:0030168 8 7 0,000 0,02417497 0,06374031 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02417497 0,06364926 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02417497 0,06355846 ! natural killer cell activation GO:0030101 7 7 0,000 0,02417497 0,06346792 ! NADP metabolic process GO:0006739 7 7 0,000 0,02417497 0,06337764 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02417497 0,06328761 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02417497 0,06319784 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02417497 0,06310833 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02417497 0,06301906 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02417497 0,06293005 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02417497 0,0628413 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02417497 0,06275279 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02417497 0,06266453 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02417497 0,06257652 ! cell-cell recognition GO:0009988 8 7 0,000 0,02417497 0,06248875 ! hormone catabolic process GO:0042447 7 7 0,000 0,02417497 0,06240123 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02417497 0,06231396 ! oxygen transport GO:0015671 7 7 0,000 0,02417497 0,06222693 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02417497 0,06214014 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02417497 0,06205359 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02417497 0,06196729 ! regulation of axon extension GO:0030516 7 7 0,000 0,02417497 0,06188122 ! cell killing GO:0001906 7 7 0,000 0,02417497 0,06179539 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02417497 0,0617098 ! adult feeding behavior GO:0008343 7 7 0,000 0,02417497 0,06162445 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02417497 0,06153934 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02417497 0,06145445 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02417497 0,06136981 ! response to cold GO:0009409 7 7 0,000 0,02417497 0,06128539 ! cell part morphogenesis GO:0032990 75 70 1,000 0,0243807 0,06172201 ! wound healing GO:0042060 74 70 1,000 0,0243807 0,06163735 ! muscle tissue development GO:0060537 72 70 1,000 0,0243807 0,06155291 ! regulation of cell activation GO:0050865 71 71 1,000 0,02503449 0,06311706 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,02569548 0,06469505 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,02569548 0,06460679 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02758248 0,06925683 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02758248 0,06916261 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02758248 0,06906864 ! positive regulation of translation GO:0045727 8 8 0,000 0,02758248 0,06897492 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02758248 0,06888146 ! superoxide anion generation GO:0042554 8 8 0,000 0,02758248 0,06878825 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02758248 0,06869529 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02758248 0,06860259 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02758248 0,06851013 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02758248 0,06841792 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02758248 0,06832596 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02758248 0,06823425 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02758248 0,06814278 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02758248 0,06805156 ! zinc ion transport GO:0006829 8 8 0,000 0,02758248 0,06796058 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02758248 0,06786985 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02758248 0,06777935 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02758248 0,0676891 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02758248 0,06759909 ! lipid localization GO:0010876 8 8 0,000 0,02758248 0,06750932 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02758248 0,06741978 ! response to cAMP GO:0051591 8 8 0,000 0,02758248 0,06733048 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02758248 0,06724142 GO:0048200|Golgi transport vesicle coating, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02758248 0,0671526 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02758248 0,067064 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02758248 0,06697565 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02758248 0,06688752 ! sensory perception of taste GO:0050909 8 8 0,000 0,02758248 0,06679963 ! organelle fusion GO:0048284 8 8 0,000 0,02758248 0,06671196 ! pancreas development GO:0031016 8 8 0,000 0,02758248 0,06662453 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02758248 0,06653732 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02758248 0,06645035 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02758248 0,0663636 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02758248 0,06627707 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02758248 0,06619078 ! sperm motility GO:0030317 8 8 0,000 0,02758248 0,0661047 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02758248 0,06601885 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02758248 0,06593322 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02758248 0,06584782 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02758248 0,06576263 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02758248 0,06567767 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02758248 0,06559292 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02758248 0,0655084 ! Golgi organization GO:0007030 8 8 0,000 0,02758248 0,06542409 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02758248 0,06533999 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02758248 0,06525612 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02758248 0,06517246 ! fructose metabolic process GO:0006000 8 8 0,000 0,02758248 0,06508901 ! mannose metabolic process GO:0006013 9 8 0,000 0,02758248 0,06500577 ! NAD metabolic process GO:0019674 8 8 0,000 0,02758248 0,06492275 ! sex determination GO:0007530 8 8 0,000 0,02758248 0,06483994 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02758248 0,06475734 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02758248 0,06467496 ! response to fungus GO:0009620 8 8 0,000 0,02758248 0,06459278 ! stem cell differentiation GO:0048863 8 8 0,000 0,02758248 0,06451081 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02758248 0,06442904 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02758248 0,06434749 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02758248 0,06426614 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02758248 0,06418499 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02758248 0,06410405 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02758248 0,06402332 ! vasoconstriction GO:0042310 8 8 0,000 0,02758248 0,06394279 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02758248 0,06386246 ! muscle cell development GO:0055001 8 8 0,000 0,02758248 0,06378233 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02758248 0,0637024 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02758248 0,06362267 ! sensory perception of pain GO:0019233 8 8 0,000 0,02758248 0,06354314 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02758248 0,06346381 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02758248 0,06338468 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02758248 0,06330575 ! chromatin silencing GO:0006342 8 8 0,000 0,02758248 0,06322701 ! tissue regeneration GO:0042246 8 8 0,000 0,02758248 0,06314847 ! salivary gland development GO:0007431 8 8 0,000 0,02758248 0,06307012 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02758248 0,06299196 ! T cell homeostasis GO:0043029 8 8 0,000 0,02758248 0,062914 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02758248 0,06283624 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02758248 0,06275866 ! water homeostasis GO:0030104 8 8 0,000 0,02758248 0,06268128 ! cofactor transport GO:0051181 8 8 0,000 0,02758248 0,06260408 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02758248 0,06252708 ! acid secretion GO:0046717 8 8 0,000 0,02758248 0,06245026 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02758248 0,06237364 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02758248 0,0622972 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02758248 0,06222095 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02758248 0,06214488 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02758248 0,06206901 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02758248 0,06199331 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02758248 0,0619178 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02758248 0,06184248 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,02758248 0,06176733 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02758248 0,06169237 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02758248 0,06161759 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02758248 0,061543 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02758248 0,06146858 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02758248 0,06139434 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02758248 0,06132028 ! developmental induction GO:0031128 8 8 0,000 0,02758248 0,0612464 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02758248 0,0611727 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02758248 0,06109918 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02758248 0,06102583 ! peptide hormone processing GO:0016486 8 8 0,000 0,02758248 0,06095266 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02758248 0,06087966 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02758248 0,06080684 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,02910653 0,06409 ! regulation of protein modification process GO:0031399 79 78 1,000 0,02980959 0,06555975 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,02980959 0,06548161 ! regulation of immune response GO:0050776 78 78 1,000 0,02980959 0,06540365 ! lactation GO:0007595 10 9 0,000 0,03097859 0,06788767 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03097859 0,06780705 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03097859 0,06772661 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03097859 0,06764637 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03097859 0,06756631 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03097859 0,06748645 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03097859 0,06740677 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,03097859 0,06732728 ! viral genome replication GO:0019079 9 9 0,000 0,03097859 0,06724798 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03097859 0,06716886 ! copper ion transport GO:0006825 9 9 0,000 0,03097859 0,06708993 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03097859 0,06701119 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03097859 0,06693263 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03097859 0,06685425 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03097859 0,06677606 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03097859 0,06669805 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03097859 0,06662023 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03097859 0,06654258 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03097859 0,06646511 ! phospholipid efflux GO:0033700 9 9 0,000 0,03097859 0,06638783 ! response to alkaloid GO:0043279 10 9 0,000 0,03097859 0,06631072 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03097859 0,0662338 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03097859 0,06615705 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03097859 0,06608048 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03097859 0,06600408 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03097859 0,06592787 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03097859 0,06585183 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03097859 0,06577596 ! methionine metabolic process GO:0006555 9 9 0,000 0,03097859 0,06570027 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03097859 0,06562475 ! cerebral cortex development GO:0021987 9 9 0,000 0,03097859 0,06554941 ! response to osmotic stress GO:0006970 9 9 0,000 0,03097859 0,06547424 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03097859 0,06539924 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03097859 0,06532441 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03097859 0,06524975 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03097859 0,06517527 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03097859 0,06510095 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03097859 0,0650268 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03097859 0,06495283 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03097859 0,06487902 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03097859 0,06480537 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03097859 0,0647319 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03097859 0,06465859 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03097859 0,06458545 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03097859 0,06451247 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03097859 0,06443965 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03097859 0,06436701 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03097859 0,06429452 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03097859 0,0642222 ! DNA replication initiation GO:0006270 9 9 0,000 0,03097859 0,06415004 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03097859 0,06407804 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03097859 0,0640062 ! histone acetylation GO:0016573 9 9 0,000 0,03097859 0,06393453 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03097859 0,06386301 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03097859 0,06379166 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03097859 0,06372046 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03097859 0,06364942 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03097859 0,06357855 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03097859 0,06350782 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03097859 0,06343726 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03097859 0,06336685 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03097859 0,0632966 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03097859 0,0632265 ! collagen catabolic process GO:0030574 9 9 0,000 0,03097859 0,06315656 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03097859 0,06308678 ! purine base metabolic process GO:0006144 9 9 0,000 0,03097859 0,06301715 ! gas transport GO:0015669 9 9 0,000 0,03097859 0,06294767 ! cholesterol efflux GO:0033344 9 9 0,000 0,03097859 0,06287834 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03097859 0,06280917 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03097859 0,06274015 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03097859 0,06267128 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03097859 0,06260256 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03097859 0,06253399 ! defense response to virus GO:0051607 9 9 0,000 0,03097859 0,06246557 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03097859 0,0623973 ! actin filament-based movement GO:0030048 9 9 0,000 0,03097859 0,06232919 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03097859 0,06226121 ! neuron projection development GO:0031175 85 80 1,000 0,03123613 0,06271045 ! MAPKKK cascade GO:0000165 82 81 1,000 0,03195951 0,06409291 ! tube development GO:0035295 83 81 1,000 0,03195951 0,06402324 ! lymphocyte activation GO:0046649 82 81 1,000 0,03195951 0,06395373 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,03416949 0,06830193 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03436332 0,06861495 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03436332 0,06854069 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03436332 0,06846659 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03436332 0,06839266 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,03436332 0,06831888 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03436332 0,06824526 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03436332 0,0681718 ! neuron maturation GO:0042551 10 10 0,000 0,03436332 0,06809849 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03436332 0,06802535 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03436332 0,06795236 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03436332 0,06787953 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03436332 0,06780685 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03436332 0,06773433 ! hormone secretion GO:0046879 10 10 0,000 0,03436332 0,06766197 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03436332 0,06758975 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03436332 0,0675177 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,03436332 0,06744579 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03436332 0,06737404 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03436332 0,06730244 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03436332 0,067231 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03436332 0,0671597 ! glial cell development GO:0021782 10 10 0,000 0,03436332 0,06708856 ! phototransduction GO:0007602 11 10 0,000 0,03436332 0,06701757 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03436332 0,06694672 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03436332 0,06687603 ! fat cell differentiation GO:0045444 10 10 0,000 0,03436332 0,06680549 ! myoblast differentiation GO:0045445 10 10 0,000 0,03436332 0,06673509 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03436332 0,06666484 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03436332 0,06659474 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03436332 0,06652479 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03436332 0,06645498 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03436332 0,06638532 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03436332 0,06631581 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03436332 0,06624644 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03436332 0,06617722 ! plasma membrane organization GO:0007009 10 10 0,000 0,03436332 0,06610814 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03436332 0,06603921 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03436332 0,06597042 ! lysosomal transport GO:0007041 10 10 0,000 0,03436332 0,06590177 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03436332 0,06583326 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03436332 0,0657649 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03436332 0,06569668 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03436332 0,0656286 ! exocrine system development GO:0035272 10 10 0,000 0,03436332 0,06556066 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03436332 0,06549286 ! embryo implantation GO:0007566 11 10 0,000 0,03436332 0,06542521 ! regulation of protein binding GO:0043393 11 10 0,000 0,03436332 0,06535769 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03436332 0,06529031 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03436332 0,06522307 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03436332 0,06515597 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03436332 0,065089 ! protein export from nucleus GO:0006611 10 10 0,000 0,03436332 0,06502218 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03436332 0,06495549 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03436332 0,06488893 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03436332 0,06482252 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03436332 0,06475624 ! histone deacetylation GO:0016575 10 10 0,000 0,03436332 0,06469009 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03436332 0,06462408 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03436332 0,06455821 ! gland morphogenesis GO:0022612 10 10 0,000 0,03436332 0,06449246 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03436332 0,06442686 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03436332 0,06436138 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03436332 0,06429604 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03436332 0,06423083 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03436332 0,06416575 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03436332 0,06410081 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03436332 0,064036 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03436332 0,06397131 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03436332 0,06390676 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03436332 0,06384234 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03436332 0,06377805 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03436332 0,06371388 ! nerve development GO:0021675 10 10 0,000 0,03436332 0,06364985 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03436332 0,06358594 ! gut development GO:0048565 10 10 0,000 0,03436332 0,06352217 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03436332 0,06345852 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03436332 0,063395 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03436332 0,0633316 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03436332 0,06326833 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03436332 0,06320519 ! protein stabilization GO:0050821 10 10 0,000 0,03436332 0,06314217 ! regulation of cellular localization GO:0060341 86 85 1,000 0,03491926 0,0640998 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,03491926 0,06403602 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,0356755 0,0653578 ! heart development GO:0007507 90 87 1,000 0,03643815 0,0666887 ! male gamete generation GO:0048232 90 88 1,000 0,03720718 0,0680286 GO:0007283|spermatogenesis, ! protein secretion GO:0009306 11 11 0,000 0,03773672 0,06892843 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,03773672 0,06886018 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,03773672 0,06879207 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,03773672 0,06872409 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03773672 0,06865625 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,03773672 0,06858854 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03773672 0,06852097 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,03773672 0,06845353 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,03773672 0,06838622 ! skin development GO:0043588 11 11 0,000 0,03773672 0,06831904 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03773672 0,06825199 ! signal complex assembly GO:0007172 11 11 0,000 0,03773672 0,06818508 ! microtubule-based transport GO:0010970 11 11 0,000 0,03773672 0,0681183 ! endothelial cell migration GO:0043542 11 11 0,000 0,03773672 0,06805165 ! peroxisomal transport GO:0043574 11 11 0,000 0,03773672 0,06798512 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03773672 0,06791873 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,03773672 0,06785247 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,03773672 0,06778634 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,03773672 0,06772033 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03773672 0,06765446 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,03773672 0,06758871 ! T cell proliferation GO:0042098 11 11 0,000 0,03773672 0,06752309 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03773672 0,0674576 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03773672 0,06739223 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03773672 0,06732699 ! spinal cord development GO:0021510 11 11 0,000 0,03773672 0,06726188 ! smooth muscle contraction GO:0006939 11 11 0,000 0,03773672 0,06719689 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,03773672 0,06713203 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03773672 0,06706729 ! digestive system process GO:0022600 11 11 0,000 0,03773672 0,06700268 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03773672 0,06693819 ! fucose metabolic process GO:0006004 11 11 0,000 0,03773672 0,06687383 ! membrane budding GO:0006900 11 11 0,000 0,03773672 0,06680959 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03773672 0,06674547 ! monoamine transport GO:0015844 11 11 0,000 0,03773672 0,06668148 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03773672 0,06661761 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03773672 0,06655386 ! body fluid secretion GO:0007589 11 11 0,000 0,03773672 0,06649023 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03773672 0,06642673 ! intermediate filament-based process GO:0045103 11 11 0,000 0,03773672 0,06636334 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03773672 0,06630008 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,03773672 0,06623694 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03773672 0,06617391 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03773672 0,06611101 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,03773672 0,06604823 ! oogenesis GO:0048477 11 11 0,000 0,03773672 0,06598556 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,03773672 0,06592302 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03773672 0,06586059 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,03773672 0,06579828 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,03773672 0,06573609 ! muscle maintenance GO:0046716 12 11 0,000 0,03773672 0,06567402 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03773672 0,06561206 ! hindbrain development GO:0030902 11 11 0,000 0,03773672 0,06555022 ! steroid catabolic process GO:0006706 11 11 0,000 0,03773672 0,0654885 ! endocrine process GO:0050886 11 11 0,000 0,03773672 0,06542689 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03773672 0,0653654 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03773672 0,06530402 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03773672 0,06524276 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03773672 0,06518161 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,03798252 0,06554475 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,03955198 0,06818924 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,03955198 0,06812551 ! DNA replication GO:0006260 91 91 1,000 0,03955198 0,0680619 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,04034599 0,06936348 ! translational initiation GO:0006413 12 12 0,000 0,04109883 0,07059194 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04109883 0,07052621 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04109883 0,0704606 ! initiation of viral infection GO:0019059 12 12 0,000 0,04109883 0,07039512 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04109883 0,07032976 ! iron ion transport GO:0006826 13 12 0,000 0,04109883 0,07026451 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04109883 0,07019939 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04109883 0,0701344 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04109883 0,07006952 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04109883 0,07000476 ! collagen metabolic process GO:0032963 12 12 0,000 0,04109883 0,06994012 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04109883 0,0698756 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04109883 0,0698112 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04109883 0,06974691 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04109883 0,06968275 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04109883 0,0696187 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04109883 0,06955477 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04109883 0,06949096 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04109883 0,06942727 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04109883 0,06936369 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04109883 0,06930023 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04109883 0,06923688 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04109883 0,06917365 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04109883 0,06911054 ! acute-phase response GO:0006953 12 12 0,000 0,04109883 0,06904754 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04109883 0,06898465 ! vacuolar transport GO:0007034 12 12 0,000 0,04109883 0,06892188 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04109883 0,06885922 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04109883 0,06879668 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04109883 0,06873425 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04109883 0,06867194 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04109883 0,06860973 ! male gonad development GO:0008584 12 12 0,000 0,04109883 0,06854764 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04109883 0,06848567 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04109883 0,0684238 ! renal system process GO:0003014 12 12 0,000 0,04109883 0,06836205 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04109883 0,0683004 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04109883 0,06823887 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04109883 0,06817745 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04109883 0,06811614 ! pallium development GO:0021543 13 12 0,000 0,04109883 0,06805494 ! cell fate determination GO:0001709 12 12 0,000 0,04109883 0,06799385 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04109883 0,06793287 ! somitogenesis GO:0001756 13 12 0,000 0,04109883 0,067872 ! G1 phase GO:0051318 13 12 0,000 0,04109883 0,06781123 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04109883 0,06775058 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04109883 0,06769003 ! detection of light stimulus GO:0009583 13 12 0,000 0,04109883 0,0676296 ! synaptogenesis GO:0007416 12 12 0,000 0,04109883 0,06756927 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04109883 0,06750904 ! hormone transport GO:0009914 12 12 0,000 0,04109883 0,06744893 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04109883 0,06738892 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04109883 0,06732902 ! spermatid differentiation GO:0048515 13 12 0,000 0,04109883 0,06726922 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04109883 0,06720954 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04109883 0,06714995 ! neural tube closure GO:0001843 13 12 0,000 0,04109883 0,06709048 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,04109883 0,0670311 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04109883 0,06697184 ! blood vessel development GO:0001568 95 94 1,000 0,04195233 0,06830224 ! regulation of cell growth GO:0001558 97 96 1,000 0,04358278 0,07089414 ! vasculature development GO:0001944 97 96 1,000 0,04358278 0,07083162 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04444968 0,07217688 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04444968 0,07211335 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04444968 0,07204992 ! gluconeogenesis GO:0006094 13 13 0,000 0,04444968 0,07198661 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04444968 0,07192341 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04444968 0,07186032 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04444968 0,07179734 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04444968 0,07173447 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04444968 0,07167171 ! regeneration GO:0031099 13 13 0,000 0,04444968 0,07160906 ! keratinization GO:0031424 13 13 0,000 0,04444968 0,07154652 ! post-embryonic development GO:0009791 14 13 0,000 0,04444968 0,07148408 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04444968 0,07142176 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04444968 0,07135955 ! vasculogenesis GO:0001570 13 13 0,000 0,04444968 0,07129744 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04444968 0,07123544 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04444968 0,07117355 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,04444968 0,07111177 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04444968 0,0710501 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04444968 0,07098853 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04444968 0,07092707 ! autophagy GO:0006914 13 13 0,000 0,04444968 0,07086571 ! receptor metabolic process GO:0043112 14 13 0,000 0,04444968 0,07080446 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04444968 0,07074332 ! ureteric bud development GO:0001657 13 13 0,000 0,04444968 0,07068228 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04444968 0,07062135 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04444968 0,07056052 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04444968 0,07049979 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04444968 0,07043918 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04444968 0,07037866 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04444968 0,07031825 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04444968 0,07025794 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04444968 0,07019774 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04444968 0,07013764 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04444968 0,07007764 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04444968 0,07001774 ! vasodilation GO:0042311 14 13 0,000 0,04444968 0,06995795 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04444968 0,06989826 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04444968 0,06983867 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04444968 0,06977918 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04444968 0,0697198 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04444968 0,06966051 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04444968 0,06960133 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04444968 0,06954224 ! immunoglobulin production GO:0002377 13 13 0,000 0,04444968 0,06948326 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04444968 0,06942437 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04444968 0,06936559 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04444968 0,0693069 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04444968 0,06924832 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04444968 0,06918983 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04444968 0,06913144 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04444968 0,06907315 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04444968 0,06901496 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04444968 0,06895687 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04444968 0,06889887 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04444968 0,06884098 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04444968 0,06878317 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04444968 0,06872547 ! blastocyst development GO:0001824 13 13 0,000 0,04444968 0,06866786 ! telomere organization GO:0032200 13 13 0,000 0,04444968 0,06861035 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04444968 0,06855294 ! regulation of amine transport GO:0051952 13 13 0,000 0,04444968 0,06849562 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04444968 0,0684384 ! regulation of system process GO:0044057 98 98 1,000 0,04523695 0,06959241 ! muscle organ development GO:0007517 102 100 1,000 0,04691448 0,07211291 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,04691448 0,07205281 ! neuron fate commitment GO:0048663 14 14 0,000 0,04778931 0,0733353 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,04778931 0,07327428 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,04778931 0,07321338 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,04778931 0,07315257 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,04778931 0,07309186 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,04778931 0,07303125 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,04778931 0,07297075 ! protein amino acid acylation GO:0043543 14 14 0,000 0,04778931 0,07291034 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,04778931 0,07285003 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,04778931 0,07278983 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,04778931 0,07272972 ! vesicle docking GO:0048278 14 14 0,000 0,04778931 0,07266971 ! superoxide metabolic process GO:0006801 15 14 0,000 0,04778931 0,0726098 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,04778931 0,07254999 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,04778931 0,07249028 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,04778931 0,07243067 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,04778931 0,07237115 ! hair cycle GO:0042633 14 14 0,000 0,04778931 0,07231173 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,04778931 0,07225241 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,04778931 0,07219319 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,04778931 0,07213406 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,04778931 0,07207503 ! lysosome organization GO:0007040 14 14 0,000 0,04778931 0,0720161 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,04778931 0,07195726 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,04778931 0,07189852 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,04778931 0,07183988 ! primary neural tube formation GO:0014020 15 14 0,000 0,04778931 0,07178133 ! peptide cross-linking GO:0018149 14 14 0,000 0,04778931 0,07172287 ! regulation of behavior GO:0050795 14 14 0,000 0,04778931 0,07166452 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,04778931 0,07160625 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,04778931 0,07154808 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,04778931 0,07149001 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,04778931 0,07143203 ! formation of primary germ layer GO:0001704 14 14 0,000 0,04778931 0,07137414 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,04778931 0,07131635 ! collagen fibril organization GO:0030199 14 14 0,000 0,04778931 0,07125865 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,04778931 0,07120104 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,04778931 0,07114353 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,04778931 0,07108611 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,04778931 0,07102878 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,04778931 0,07097155 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,04778931 0,0709144 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,04778931 0,07085735 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,04778931 0,07080039 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,04778931 0,07074353 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05111774 0,07560995 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05111774 0,07554932 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05111774 0,07548878 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05111774 0,07542834 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05111774 0,075368 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05111774 0,07530776 ! response to vitamin GO:0033273 15 15 0,000 0,05111774 0,07524761 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,05111774 0,07518755 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05111774 0,07512759 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05111774 0,07506773 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,05111774 0,07500796 ! ovarian follicle development GO:0001541 15 15 0,000 0,05111774 0,07494829 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05111774 0,07488871 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05111774 0,07482923 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05111774 0,07476984 ! heme metabolic process GO:0042168 15 15 0,000 0,05111774 0,07471055 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05111774 0,07465135 ! chromosome condensation GO:0030261 15 15 0,000 0,05111774 0,07459224 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05111774 0,07453323 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05111774 0,07447431 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05111774 0,07441548 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05111774 0,07435675 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05111774 0,07429811 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05111774 0,07423956 ! phospholipid transport GO:0015914 15 15 0,000 0,05111774 0,0741811 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05111774 0,07412274 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05111774 0,07406447 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05111774 0,07400629 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05111774 0,0739482 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05111774 0,0738902 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05111774 0,07383229 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05111774 0,07377447 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05111774 0,07371675 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05111774 0,07365911 ! protein homooligomerization GO:0051260 15 15 0,000 0,05111774 0,07360156 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05111774 0,07354411 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05443503 0,07825566 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05443503 0,07819467 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05443503 0,07813377 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05443503 0,07807297 ! circadian rhythm GO:0007623 16 16 0,000 0,05443503 0,07801226 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05443503 0,07795164 ! vacuole organization GO:0007033 16 16 0,000 0,05443503 0,07789112 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05443503 0,07783069 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05443503 0,07777036 ! vesicle targeting GO:0006903 17 16 0,000 0,05443503 0,07771012 ! segmentation GO:0035282 17 16 0,000 0,05443503 0,07764997 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05443503 0,07758992 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05443503 0,07752995 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05443503 0,07747009 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05443503 0,07741031 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05443503 0,07735063 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05443503 0,07729103 ! cell fate specification GO:0001708 16 16 0,000 0,05443503 0,07723153 ! pentose metabolic process GO:0019321 16 16 0,000 0,05443503 0,07717212 ! fatty acid transport GO:0015908 16 16 0,000 0,05443503 0,07711281 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05443503 0,07705358 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05443503 0,07699444 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05443503 0,0769354 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05443503 0,07687645 ! polyol metabolic process GO:0019751 16 16 0,000 0,05443503 0,07681758 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05443503 0,07675881 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05443503 0,07670012 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05443503 0,07664153 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05443503 0,07658302 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05443503 0,07652461 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05443503 0,07646628 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05443503 0,07640804 ! regulation of coagulation GO:0050818 17 16 0,000 0,05443503 0,07634989 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0577412 0,0809255 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,0577412 0,08086401 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0577412 0,08080261 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0577412 0,0807413 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0577412 0,08068009 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0577412 0,08061897 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0577412 0,08055794 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,0577412 0,080497 ! sensory perception of smell GO:0007608 17 17 0,000 0,0577412 0,08043616 ! glucose transport GO:0015758 17 17 0,000 0,0577412 0,0803754 ! cell junction assembly GO:0034329 18 17 0,000 0,0577412 0,08031474 ! tissue remodeling GO:0048771 17 17 0,000 0,0577412 0,08025417 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0577412 0,0801937 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0577412 0,08013331 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0577412 0,08007301 ! neural crest cell development GO:0014032 19 17 0,000 0,0577412 0,08001281 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,0577412 0,07995269 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0577412 0,07989267 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0577412 0,07983273 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,0577412 0,07977289 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0577412 0,07971314 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0577412 0,07965347 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0577412 0,07959389 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0577412 0,07953441 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0577412 0,07947501 ! embryonic organ development GO:0048568 17 17 0,000 0,0577412 0,0794157 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0577412 0,07935648 ! liver development GO:0001889 17 17 0,000 0,0577412 0,07929734 ! gene silencing GO:0016458 17 17 0,000 0,0577412 0,0792383 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06103629 0,08369783 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06103629 0,0836356 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,06103629 0,08357347 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06103629 0,08351142 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,06103629 0,08344947 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06103629 0,08338761 ! membrane docking GO:0022406 18 18 0,000 0,06103629 0,08332584 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06103629 0,08326417 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06103629 0,08320258 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06103629 0,08314109 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06103629 0,08307968 ! hexose transport GO:0008645 18 18 0,000 0,06103629 0,08301837 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06103629 0,08295714 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,06103629 0,08289601 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06103629 0,08283497 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06103629 0,08277402 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06103629 0,08271315 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06103629 0,08265238 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06103629 0,08259169 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06103629 0,0825311 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06103629 0,08247059 ! BMP signaling pathway GO:0030509 18 18 0,000 0,06103629 0,08241017 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06103629 0,08234985 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,06103629 0,0822896 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06103629 0,08222945 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06432034 0,08659049 ! glial cell differentiation GO:0010001 19 19 0,000 0,06432034 0,08652729 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,06432034 0,08646418 ! feeding behavior GO:0007631 19 19 0,000 0,06432034 0,08640116 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,06432034 0,08633823 ! peroxisome organization GO:0007031 19 19 0,000 0,06432034 0,08627539 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06432034 0,08621264 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06432034 0,08614999 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06432034 0,08608743 ! metanephros development GO:0001656 19 19 0,000 0,06432034 0,08602495 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06432034 0,08596257 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,06432034 0,08590028 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06432034 0,08583808 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06432034 0,08577597 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06432034 0,08571395 ! regulation of protein stability GO:0031647 19 19 0,000 0,06432034 0,08565201 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06432034 0,08559017 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06432034 0,08552842 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,06432034 0,08546675 ! eye morphogenesis GO:0048592 19 19 0,000 0,06432034 0,08540518 ! regulation of cell shape GO:0008360 21 19 0,000 0,06432034 0,08534369 ! placenta development GO:0001890 19 19 0,000 0,06432034 0,08528229 ! response to heat GO:0009408 19 19 0,000 0,06432034 0,08522098 ! vesicle localization GO:0051648 20 19 0,000 0,06432034 0,08515976 ! regulation of muscle development GO:0048634 21 20 0,000 0,06759338 0,089429 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,06759338 0,08936485 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,06759338 0,08930079 ! negative regulation of binding GO:0051100 21 20 0,000 0,06759338 0,08923682 ! organic ether metabolic process GO:0018904 20 20 0,000 0,06759338 0,08917294 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,06759338 0,08910915 ! neural tube development GO:0021915 21 20 0,000 0,06759338 0,08904546 ! nucleus organization GO:0006997 20 20 0,000 0,06759338 0,08898185 ! phagocytosis GO:0006909 21 20 0,000 0,06759338 0,08891834 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,06759338 0,08885492 ! protein targeting to membrane GO:0006612 22 20 0,000 0,06759338 0,08879159 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,06759338 0,08872834 ! chromatin remodeling GO:0006338 20 20 0,000 0,06759338 0,08866519 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,06759338 0,08860213 ! lipid oxidation GO:0034440 20 20 0,000 0,06759338 0,08853916 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,06759338 0,08847627 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,06759338 0,08841348 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,06759338 0,08835078 ! RNA modification GO:0009451 20 20 0,000 0,06759338 0,08828816 ! single fertilization GO:0007338 21 20 0,000 0,06759338 0,08822563 ! regulation of B cell activation GO:0050864 20 20 0,000 0,06759338 0,0881632 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07085544 0,0923526 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,07085544 0,09228734 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,07085544 0,09222216 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,07085544 0,09215708 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07085544 0,09209209 ! Notch signaling pathway GO:0007219 22 21 0,000 0,07085544 0,09202719 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,07085544 0,09196238 ! ear morphogenesis GO:0042471 21 21 0,000 0,07085544 0,09189766 ! organic anion transport GO:0015711 21 21 0,000 0,07085544 0,09183304 ! cholesterol transport GO:0030301 21 21 0,000 0,07085544 0,0917685 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07085544 0,09170406 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07085544 0,0916397 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,07085544 0,09157544 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07085544 0,09151127 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,07085544 0,09144718 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,07085544 0,09138319 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07085544 0,09131929 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,07085544 0,09125547 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,07085544 0,09119175 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,07410657 0,09530942 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,07410657 0,09524296 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,07410657 0,09517659 ! regulation of ion transport GO:0043269 22 22 0,000 0,07410657 0,09511031 ! cell junction organization GO:0034330 23 22 0,000 0,07410657 0,09504412 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,07410657 0,09497803 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,07410657 0,09491202 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,07410657 0,09484611 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,07410657 0,09478029 ! ovulation cycle process GO:0022602 22 22 0,000 0,07410657 0,09471457 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,07410657 0,09464893 ! cell chemotaxis GO:0060326 23 22 0,000 0,07410657 0,09458338 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,07410657 0,09451793 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,07410657 0,09445256 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,07410657 0,09438729 ! biopolymer methylation GO:0043414 22 22 0,000 0,07410657 0,0943221 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,07410657 0,09425701 ! detection of external stimulus GO:0009581 23 22 0,000 0,07410657 0,094192 ! neuron migration GO:0001764 22 22 0,000 0,07410657 0,09412709 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,07410657 0,09406226 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,07410657 0,09399752 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,07410657 0,09393288 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,07410657 0,09386832 ! aerobic respiration GO:0009060 22 22 0,000 0,07410657 0,09380385 ! cytokine production GO:0001816 22 22 0,000 0,07410657 0,09373947 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,07410657 0,09367517 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,07734679 0,097704 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,07734679 0,09763708 ! viral infectious cycle GO:0019058 23 23 0,000 0,07734679 0,09757025 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,07734679 0,09750351 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,07734679 0,09743686 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,07734679 0,09737031 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,07734679 0,09730384 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,07734679 0,09723747 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,07734679 0,09717119 ! endocrine system development GO:0035270 23 23 0,000 0,07734679 0,09710499 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,07734679 0,09703889 ! positive regulation of growth GO:0045927 23 23 0,000 0,07734679 0,09697288 ! female gonad development GO:0008585 23 23 0,000 0,07734679 0,09690696 ! lipid homeostasis GO:0055088 23 23 0,000 0,07734679 0,09684112 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,07734679 0,09677538 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,07734679 0,09670972 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,07734679 0,09664416 ! cell projection assembly GO:0030031 25 23 0,000 0,07734679 0,09657868 ! gliogenesis GO:0042063 24 24 0,000 0,08057614 0,10054288 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,08057614 0,10047485 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08057614 0,10040692 ! glucose homeostasis GO:0042593 24 24 0,000 0,08057614 0,10033907 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08057614 0,10027132 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,08057614 0,10020366 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08057614 0,1001361 ! ovulation cycle GO:0042698 24 24 0,000 0,08057614 0,10006862 ! fertilization GO:0009566 25 24 0,000 0,08057614 0,10000123 ! maintenance of protein location GO:0045185 25 24 0,000 0,08057614 0,09993394 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08057614 0,09986673 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,08057614 0,09979962 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,08057614 0,09973259 ! glucan metabolic process GO:0044042 25 24 0,000 0,08057614 0,09966566 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,08379466 0,10357717 ! negative regulation of secretion GO:0051048 26 25 0,000 0,08379466 0,10350775 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,08379466 0,10343842 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,08379466 0,10336919 ! cellular component disassembly GO:0022411 26 25 0,000 0,08379466 0,10330004 ! endosome transport GO:0016197 25 25 0,000 0,08379466 0,10323099 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,08379466 0,10316203 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,08379466 0,10309317 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,08379466 0,10302439 ! excretion GO:0007588 25 25 0,000 0,08379466 0,10295571 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,08379466 0,10288712 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,08379466 0,10281862 ! gastrulation GO:0007369 25 25 0,000 0,08379466 0,10275021 ! heart morphogenesis GO:0003007 25 25 0,000 0,08379466 0,10268189 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,08379466 0,10261366 ! regulation of endocytosis GO:0030100 25 25 0,000 0,08379466 0,10254553 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,08379466 0,10247748 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,08379466 0,10240952 ! positive regulation of binding GO:0051099 27 26 0,000 0,08700238 0,10625937 ! positive regulation of defense response GO:0031349 26 26 0,000 0,08700238 0,106189 ! glycolysis GO:0006096 26 26 0,000 0,08700238 0,10611872 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,08700238 0,10604854 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,08700238 0,10597845 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,08700238 0,10590845 ! cellular defense response GO:0006968 26 26 0,000 0,08700238 0,10583854 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,08700238 0,10576873 ! regulation of protein secretion GO:0050708 26 26 0,000 0,08700238 0,10569901 ! germ cell development GO:0007281 27 26 0,000 0,08700238 0,10562938 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,08700238 0,10555984 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,08700238 0,10549039 ! response to insulin stimulus GO:0032868 28 26 0,000 0,08700238 0,10542103 ! maintenance of location in cell GO:0051651 27 26 0,000 0,08700238 0,10535177 ! chloride transport GO:0006821 27 27 0,000 0,09019934 0,10915127 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09019934 0,10907965 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,09019934 0,10900812 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09019934 0,10893669 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,09019934 0,10886535 ! peptide metabolic process GO:0006518 29 27 0,000 0,09019934 0,1087941 ! mesenchymal cell development GO:0014031 29 27 0,000 0,09019934 0,10872295 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,09019934 0,10865189 ! defense response to bacterium GO:0042742 27 27 0,000 0,09019934 0,10858092 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,09019934 0,10851004 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09019934 0,10843926 ! cell growth GO:0016049 27 27 0,000 0,09019934 0,10836857 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,09338557 0,11212352 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,09338557 0,11205052 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 0,000 0,09338557 0,11197762 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,09338557 0,11190481 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,09338557 0,1118321 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,09338557 0,11175948 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,09338557 0,11168696 ! histone modification GO:0016570 28 28 0,000 0,09338557 0,11161453 ! developmental growth GO:0048589 28 28 0,000 0,09338557 0,11154219 ! cartilage development GO:0051216 29 28 0,000 0,09338557 0,11146995 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,0965611 0,11518583 ! viral reproductive process GO:0022415 29 29 0,000 0,0965611 0,11511132 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,0965611 0,11503691 ! leukocyte migration GO:0050900 30 29 0,000 0,0965611 0,1149626 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,0965611 0,11488838 ! antigen processing and presentation GO:0019882 29 29 0,000 0,0965611 0,11481426 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,0965611 0,11474024 ! tRNA processing GO:0008033 29 29 0,000 0,0965611 0,11466631 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,0965611 0,11459247 ! covalent chromatin modification GO:0016569 29 29 0,000 0,0965611 0,11451873 ! adult behavior GO:0030534 30 29 0,000 0,0965611 0,11444509 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,0965611 0,11437153 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,0965611 0,11429808 ! transition metal ion transport GO:0000041 31 30 0,000 0,09972597 0,11796853 ! RNA catabolic process GO:0006401 30 30 0,000 0,09972597 0,11789286 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,09972597 0,11781729 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,09972597 0,11774181 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,09972597 0,11766643 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,09972597 0,11759115 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,09972597 0,11751596 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,09972597 0,11744087 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,09972597 0,11736588 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,09972597 0,11729098 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,09972597 0,11721618 ! response to temperature stimulus GO:0009266 30 30 0,000 0,09972597 0,11714147 ! regulation of ossification GO:0030278 30 30 0,000 0,09972597 0,11706686 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,09972597 0,11699234 ! regulation of inflammatory response GO:0050727 30 30 0,000 0,09972597 0,11691792 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,09972597 0,11684359 ! vesicle organization GO:0016050 30 30 0,000 0,09972597 0,11676936 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,09972597 0,11669522 ! regulation of translational initiation GO:0006446 31 31 0,000 0,10288022 0,1203098 ! membrane fusion GO:0006944 31 31 0,000 0,10288022 0,12023351 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,10288022 0,12015731 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,10288022 0,12008121 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,10288022 0,12000521 ! ion transmembrane transport GO:0034220 31 31 0,000 0,10288022 0,11992931 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,10288022 0,1198535 ! digestion GO:0007586 31 31 0,000 0,10288022 0,11977779 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,10288022 0,11970217 ! regulation of heart contraction GO:0008016 31 31 0,000 0,10288022 0,11962665 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,10288022 0,11955122 ! camera-type eye development GO:0043010 31 31 0,000 0,10288022 0,11947589 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,10288022 0,11940065 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,10288022 0,11932551 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,10288022 0,11925046 ! cell redox homeostasis GO:0045454 32 32 0,000 0,10602387 0,12281709 ! glucose catabolic process GO:0006007 32 32 0,000 0,10602387 0,12273994 ! lipid modification GO:0030258 32 32 0,000 0,10602387 0,12266289 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,10602387 0,12258594 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,10602387 0,12250908 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,10602387 0,12243232 ! cell maturation GO:0048469 32 32 0,000 0,10602387 0,12235566 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,10602387 0,12227909 ! kidney development GO:0001822 32 32 0,000 0,10602387 0,12220262 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,10602387 0,12212624 ! maintenance of location GO:0051235 33 32 0,000 0,10602387 0,12204996 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,10915696 0,1255782 ! amino acid transport GO:0006865 33 33 0,000 0,10915696 0,12549986 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,10915696 0,12542162 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,10915696 0,12534348 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,10915696 0,12526543 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,10915696 0,12518748 ! regulation of actin filament length GO:0030832 34 34 0,000 0,11227953 0,12868854 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,11227953 0,12860856 ! response to metal ion GO:0010038 34 34 0,000 0,11227953 0,12852868 ! ear development GO:0043583 34 34 0,000 0,11227953 0,1284489 ! muscle cell differentiation GO:0042692 35 34 0,000 0,11227953 0,12836922 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,11227953 0,12828963 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,11227953 0,12821015 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,11227953 0,12813076 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,11227953 0,12805147 ! secondary metabolic process GO:0019748 34 34 0,000 0,11227953 0,12797228 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,11227953 0,12789319 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,11227953 0,12781419 ! viral reproduction GO:0016032 34 34 0,000 0,11227953 0,12773529 ! detection of stimulus GO:0051606 36 34 0,000 0,11227953 0,12765649 ! regulation of cellular component size GO:0032535 35 35 0,000 0,11539161 0,1311139 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,11539161 0,13103311 ! mesoderm development GO:0007498 35 35 0,000 0,11539161 0,13095243 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,11539161 0,13087184 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,11539161 0,13079135 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,11539161 0,13071096 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,11539161 0,13063067 ! inorganic anion transport GO:0015698 35 35 0,000 0,11539161 0,13055048 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,11539161 0,13047039 ! regulation of immune effector process GO:0002697 35 35 0,000 0,11539161 0,1303904 ! hydrogen transport GO:0006818 36 36 0,000 0,11849323 0,13381313 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,11849323 0,13373119 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,11849323 0,13364934 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,11849323 0,1335676 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,11849323 0,13348596 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,11849323 0,13340442 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,11849323 0,13332297 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,11849323 0,13324163 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,11849323 0,13316038 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,11849323 0,13307924 ! gonad development GO:0008406 36 36 0,000 0,11849323 0,13299819 ! regulation of lipase activity GO:0060191 36 36 0,000 0,11849323 0,13291724 ! coagulation GO:0050817 39 36 0,000 0,11849323 0,13283639 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,12158443 0,13621891 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,12158443 0,13613615 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 37 37 0,000 0,12158443 0,13605349 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,12158443 0,13597094 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,12158443 0,13588848 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,12158443 0,13580613 ! positive regulation of secretion GO:0051047 39 38 0,000 0,12466524 0,13916295 ! neurotransmitter transport GO:0006836 40 38 0,000 0,12466524 0,13907871 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,12466524 0,13899458 ! exocytosis GO:0006887 40 38 0,000 0,12466524 0,13891054 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,12466524 0,13882661 ! urogenital system development GO:0001655 38 38 0,000 0,12466524 0,13874278 ! hexose catabolic process GO:0019320 38 38 0,000 0,12466524 0,13865904 ! RNA elongation GO:0006354 38 38 0,000 0,12466524 0,13857541 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,12466524 0,13849188 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,12466524 0,13840846 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,12773569 0,14173202 ! hemostasis GO:0007599 42 39 0,000 0,12773569 0,14164674 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,12773569 0,14156156 ! activation of MAPK activity GO:0000187 39 39 0,000 0,12773569 0,14147649 ! response to unfolded protein GO:0006986 39 39 0,000 0,12773569 0,14139152 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,12773569 0,14130665 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,12773569 0,14122188 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,12773569 0,14113722 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,12773569 0,14105265 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,12773569 0,14096819 ! developmental maturation GO:0021700 39 39 0,000 0,12773569 0,14088383 ! limb development GO:0060173 39 39 0,000 0,12773569 0,14079957 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,13079582 0,14408649 ! DNA catabolic process GO:0006308 41 40 0,000 0,13079582 0,14400042 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,13079582 0,14391445 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,13079582 0,14382858 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,13384566 0,14709454 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,13384566 0,14700688 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,13384566 0,14691933 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,13384566 0,14683188 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,13384566 0,14674453 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,13384566 0,14665728 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,13688524 0,14989869 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,13688524 0,14980968 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,13688524 0,14972077 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,13688524 0,14963197 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,13688524 0,14954327 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,13688524 0,14945468 ! forebrain development GO:0030900 43 42 0,000 0,13688524 0,14936619 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,13688524 0,14927781 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,13688524 0,14918953 ! reproductive structure development GO:0048608 43 43 0,000 0,1399146 0,15240107 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1399146 0,15231105 ! alcohol catabolic process GO:0046164 43 43 0,000 0,1399146 0,15222114 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,1399146 0,15213133 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,1399146 0,15204163 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,14293377 0,15523096 ! mRNA transport GO:0051028 44 44 0,000 0,14293377 0,15513954 ! vitamin metabolic process GO:0006766 44 44 0,000 0,14293377 0,15504823 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,14293377 0,15495702 ! amine biosynthetic process GO:0009309 46 45 0,000 0,14594278 0,15812613 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,14594278 0,15803322 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,14594278 0,15794042 ! regulation of DNA binding GO:0051101 47 45 0,000 0,14594278 0,15784774 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,14594278 0,15775516 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,14594278 0,15766269 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,14594278 0,15757032 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,14894166 0,16071398 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,14894166 0,16061994 ! tube morphogenesis GO:0035239 47 46 0,000 0,14894166 0,16052601 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,14894166 0,16043219 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,14894166 0,16033848 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,14894166 0,16024488 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,14894166 0,16015139 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,15193045 0,16326987 ! regulation of blood pressure GO:0008217 48 47 0,000 0,15193045 0,16317472 ! amine transport GO:0015837 47 47 0,000 0,15193045 0,16307969 ! rhythmic process GO:0048511 47 47 0,000 0,15193045 0,16298477 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,15490919 0,16608355 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,15490919 0,16598699 ! DNA recombination GO:0006310 48 48 0,000 0,15490919 0,16589055 ! ossification GO:0001503 50 49 0,000 0,15787789 0,16897151 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,15787789 0,16887345 ! response to nutrient GO:0007584 49 49 0,000 0,15787789 0,16877549 ! response to bacterium GO:0009617 50 49 0,000 0,15787789 0,16867765 ! regulation of ligase activity GO:0051340 50 49 0,000 0,15787789 0,16857992 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,15787789 0,16848231 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,15787789 0,16838481 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,1608366 0,17144121 ! chromatin assembly GO:0031497 50 50 0,000 0,1608366 0,17134211 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,1608366 0,17124312 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,1608366 0,17114425 ! transcription initiation GO:0006352 50 50 0,000 0,1608366 0,1710455 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,1608366 0,17094685 ! rRNA metabolic process GO:0016072 51 51 0,000 0,16378534 0,17398062 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,16378534 0,1738804 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,16378534 0,1737803 ! RNA localization GO:0006403 52 52 0,000 0,16672415 0,17679667 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,16672415 0,176695 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,16672415 0,17659346 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,16672415 0,17649202 ! sodium ion transport GO:0006814 53 53 0,000 0,16965307 0,17948944 ! tRNA metabolic process GO:0006399 53 53 0,000 0,16965307 0,17938646 ! response to hypoxia GO:0001666 53 53 0,000 0,16965307 0,1792836 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,16965307 0,17918086 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,16965307 0,17907824 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,16965307 0,17897573 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,17257211 0,18195103 ! response to oxygen levels GO:0070482 55 54 0,000 0,17257211 0,181847 ! response to virus GO:0009615 54 54 0,000 0,17257211 0,18174309 ! hormone metabolic process GO:0042445 55 54 0,000 0,17257211 0,18163929 ! sulfur metabolic process GO:0006790 55 54 0,000 0,17257211 0,18153562 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,17257211 0,18143206 ! nucleosome organization GO:0034728 55 55 0,000 0,17548132 0,18438545 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,17548132 0,18428039 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,17838073 0,1872185 ! regulation of binding GO:0051098 60 57 0,000 0,18127036 0,19014302 ! ATP metabolic process GO:0046034 57 57 0,000 0,18127036 0,19003486 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,18127036 0,18992682 ! dephosphorylation GO:0016311 60 59 0,000 0,18702044 0,19584015 ! carboxylic acid transport GO:0046942 59 59 0,000 0,18702044 0,19572894 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,18702044 0,19561786 ! potassium ion transport GO:0006813 60 60 0,000 0,18988094 0,19849721 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,18988094 0,19838468 ! cellular respiration GO:0045333 62 61 0,000 0,1927318 0,20124913 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,1927318 0,20113517 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,1927318 0,20102134 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,1927318 0,20090764 ! lipid transport GO:0006869 62 62 0,000 0,19557305 0,20375417 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,19557305 0,20363905 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,19557305 0,20352407 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,19557305 0,20340921 ! regulation of secretion GO:0051046 65 63 0,000 0,19840471 0,20623794 ! glucose metabolic process GO:0006006 63 63 0,000 0,19840471 0,20612169 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,19840471 0,20600556 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,19840471 0,20588957 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,20122681 0,20870063 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,20122681 0,20858325 ! angiogenesis GO:0001525 65 64 0,000 0,20122681 0,208466 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,20122681 0,20834888 ! anion transport GO:0006820 65 65 0,000 0,20403939 0,21114239 ! regulation of hormone levels GO:0010817 66 65 0,000 0,20403939 0,2110239 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,20684248 0,21380297 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,20684248 0,21368312 ! DNA packaging GO:0006323 66 66 0,000 0,20684248 0,21356341 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,20684248 0,21344384 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,20963611 0,21620557 ! muscle contraction GO:0006936 67 67 0,000 0,20963611 0,21608465 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,21242031 0,2188321 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,21242031 0,21870985 ! regulation of translation GO:0006417 69 69 0,000 0,2151951 0,22144309 ! sensory perception of sound GO:0007605 71 69 0,000 0,2151951 0,22131952 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,2151951 0,22119608 ! positive regulation of transport GO:0051050 71 70 0,000 0,21796053 0,22391374 ! growth GO:0040007 70 70 0,000 0,21796053 0,223789 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,21796053 0,2236644 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,22071661 0,22636657 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,22071661 0,22624067 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,22071661 0,22611491 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,22071661 0,22598929 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,22071661 0,22586381 ! secretion by cell GO:0032940 75 72 0,000 0,22346339 0,22854774 ! muscle system process GO:0003012 72 72 0,000 0,22346339 0,22842098 ! sensory organ development GO:0007423 72 72 0,000 0,22346339 0,22829436 ! regulation of cytokine production GO:0001817 72 72 0,000 0,22346339 0,22816788 ! electron transport chain GO:0022900 75 74 0,000 0,22892914 0,23361927 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,22892914 0,23348998 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,23164816 0,2361325 ! response to oxidative stress GO:0006979 76 75 0,000 0,23164816 0,23600197 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,23164816 0,23587158 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,234358 0,23849906 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,234358 0,23836744 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,23705868 0,24098132 ! microtubule-based movement GO:0007018 82 78 0,000 0,23975022 0,24358306 ! metal ion homeostasis GO:0055065 78 78 0,000 0,23975022 0,24344885 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,24510604 0,24875024 ! lipid catabolic process GO:0016042 82 81 0,000 0,24777037 0,2513158 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,25307203 0,25655212 ! ncRNA processing GO:0034470 83 83 0,000 0,25307203 0,25641108 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,25307203 0,25627019 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,25833786 0,26145891 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,25833786 0,26131541 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,26095742 0,26382036 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,26095742 0,26367573 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,26616996 0,2687952 ! chemotaxis GO:0006935 90 89 0,000 0,268763 0,27126517 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,27134725 0,27372358 ! brain development GO:0007420 91 90 0,000 0,27134725 0,27357385 ! visual perception GO:0007601 93 92 0,000 0,27648954 0,27860591 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,27648954 0,27845367 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,27648954 0,27830159 ! tissue morphogenesis GO:0048729 94 93 0,000 0,27904762 0,28072312 ! regulation of response to stress GO:0080134 97 94 0,000 0,28159703 0,28313329 ! pattern specification process GO:0007389 96 94 0,000 0,28159703 0,28297891 ! epidermis development GO:0008544 94 94 0,000 0,28159703 0,2828247 ! cofactor metabolic process GO:0051186 95 94 0,000 0,28159703 0,28267065 ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,29170855 0,29266132 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,29170855 0,29250209 ! blood circulation GO:0008015 99 98 0,000 0,29170855 0,29234304 GO:0003013|circulatory system process, ! anti-apoptosis GO:0006916 100 99 0,000 0,29421503 0,29469473 ! ectoderm development GO:0007398 99 99 0,000 0,29421503 0,29453466 ! response to hormone stimulus GO:0009725 102 100 0,000 0,29671302 0,2968741 ! response to other organism GO:0051707 101 100 0,000 0,29671302 0,29671302