pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6832-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 1,426E-06 3,431E-03 ! protein sumoylation GO:0016925 15 10 2,000 1,426E-06 1,716E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 3,203E-06 2,568E-03 ! response to X-ray GO:0010165 25 13 2,000 3,382E-06 2,034E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 3,71E-06 1,785E-03 ! cell cycle arrest GO:0007050 213 100 4,000 3,721E-06 1,492E-03 ! pigmentation GO:0043473 100 46 3,000 4,056E-06 1,394E-03 ! response to gamma radiation GO:0010332 28 14 2,000 4,297E-06 1,292E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 4,297E-06 1,149E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 2,000 7,988E-06 1,922E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 8,97E-06 1,962E-03 ! centrosome cycle GO:0007098 25 18 2,000 9,569E-06 1,919E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 1,183E-05 2,189E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,332E-05 2,29E-03 ! cell aging GO:0007569 44 21 2,000 1,552E-05 2,489E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 1,794E-05 2,698E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 2,666E-05 3,773E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 2,666E-05 3,563E-03 ! microtubule organizing center organization GO:0031023 39 26 2,000 3,009E-05 3,81E-03 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 3,009E-05 3,619E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 3,379E-05 3,871E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 3,379E-05 3,695E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 3,778E-05 3,952E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 4,207E-05 4,218E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 5,158E-05 4,964E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 5,301E-05 4,906E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 5,301E-05 4,724E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 5,301E-05 4,555E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 5,301E-05 4,398E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 5,301E-05 4,252E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 5,301E-05 4,114E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 5,301E-05 3,986E-03 GO:0051930|regulation of sensory perception of pain, ! response to ionizing radiation GO:0010212 65 32 2,000 5,682E-05 4,143E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 7,461E-05 5,28E-03 ! sleep GO:0030431 13 6 1,000 7,94E-05 5,458E-03 ! male meiosis GO:0007140 7 6 1,000 7,94E-05 5,306E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 7,94E-05 5,163E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 7,94E-05 5,027E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 12 6 1,000 7,94E-05 4,898E-03 GO:0051653|spindle localization, ! response to UV-C GO:0010225 11 6 1,000 7,94E-05 4,776E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 7,94E-05 4,659E-03 ! mammary gland development GO:0030879 86 39 2,000 1,035E-04 5,928E-03 ! learning GO:0007612 77 39 2,000 1,035E-04 5,791E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,11E-04 6,069E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 1,11E-04 5,934E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,11E-04 5,805E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,11E-04 5,682E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 1,11E-04 5,563E-03 ! centrosome duplication GO:0051298 13 7 1,000 1,11E-04 5,45E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,11E-04 5,341E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,11E-04 5,236E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,11E-04 5,135E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,11E-04 5,039E-03 ! cytokinesis GO:0000910 72 40 2,000 1,117E-04 4,977E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,388E-04 6,073E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,478E-04 6,349E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,478E-04 6,237E-03 ! ER overload response GO:0006983 12 8 1,000 1,478E-04 6,13E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,478E-04 6,026E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,478E-04 5,925E-03 ! blastocyst growth GO:0001832 19 8 1,000 1,478E-04 5,828E-03 ! double-strand break repair GO:0006302 81 44 2,000 1,487E-04 5,772E-03 ! Golgi to endosome transport GO:0006895 23 9 1,000 1,897E-04 7,245E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,897E-04 7,131E-03 ! motor axon guidance GO:0008045 16 9 1,000 1,897E-04 7,022E-03 ! response to amine stimulus GO:0014075 13 9 1,000 1,897E-04 6,915E-03 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,897E-04 6,812E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,897E-04 6,712E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,929E-04 6,728E-03 ! activation of caspase activity GO:0006919 84 48 2,000 1,929E-04 6,632E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 2,368E-04 8,023E-03 ! multicellular organism growth GO:0035264 18 10 1,000 2,368E-04 7,912E-03 ! apical protein localization GO:0045176 15 10 1,000 2,368E-04 7,804E-03 ! oocyte development GO:0048599 17 10 1,000 2,368E-04 7,698E-03 ! response to UV GO:0009411 104 53 2,000 2,592E-04 8,314E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,889E-04 9,147E-03 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 2,889E-04 9,029E-03 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of intracellular pH GO:0051453 19 11 1,000 2,889E-04 8,913E-03 ! oocyte differentiation GO:0009994 18 11 1,000 2,889E-04 8,8E-03 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 2,889E-04 8,69E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 2,889E-04 8,583E-03 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,893E-04 8,488E-03 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 2,893E-04 8,386E-03 ! aging GO:0007568 103 55 2,000 2,893E-04 8,286E-03 ! nucleotide-excision repair GO:0006289 83 56 2,000 3,051E-04 8,637E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,216E-04 8,996E-03 ! asymmetric protein localization GO:0008105 20 12 1,000 3,462E-04 9,575E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 3,462E-04 9,466E-03 GO:0042130|negative regulation of T cell proliferation, ! DNA damage response, signal transduction GO:0042770 128 60 2,000 3,742E-04 0,01011597 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 4,085E-04 0,01092182 GO:0000725|recombinational repair, ! regulation of cellular pH GO:0030641 22 13 1,000 4,085E-04 0,0108018 ! actin filament polymerization GO:0030041 24 13 1,000 4,085E-04 0,01068439 ! acrosome reaction GO:0007340 18 13 1,000 4,085E-04 0,0105695 ! regulation of homeostatic process GO:0032844 134 62 2,000 4,122E-04 0,01055037 ! positive regulation of cell motion GO:0051272 146 64 2,000 4,526E-04 0,01146221 ! reproductive cellular process GO:0048610 20 14 1,000 4,759E-04 0,01192779 ! regulation of S phase GO:0033261 23 14 1,000 4,759E-04 0,01180482 ! regulation of mRNA processing GO:0050684 24 14 1,000 4,759E-04 0,01168436 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,759E-04 0,01156634 ! male genitalia development GO:0030539 24 14 1,000 4,759E-04 0,01145068 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 5,178E-04 0,01233463 ! activation of immune response GO:0002253 105 67 2,000 5,178E-04 0,01221371 ! negative regulation of kinase activity GO:0033673 131 68 2,000 5,408E-04 0,01263237 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 1,000 5,483E-04 0,01268507 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,483E-04 0,01256426 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,483E-04 0,01244573 ! dopamine metabolic process GO:0042417 35 15 1,000 5,483E-04 0,01232941 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 6,257E-04 0,01393932 ! startle response GO:0001964 28 16 1,000 6,257E-04 0,01381143 ! activation of MAPKK activity GO:0000186 35 16 1,000 6,257E-04 0,01368587 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 6,257E-04 0,01356258 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,257E-04 0,01344148 ! regulation of caspase activity GO:0043281 122 72 2,000 6,393E-04 0,01361195 ! negative regulation of transferase activity GO:0051348 140 72 2,000 6,393E-04 0,01349255 ! learning or memory GO:0007611 147 73 2,000 6,656E-04 0,01392531 ! meiosis GO:0007126 121 74 2,000 6,926E-04 0,01436472 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,926E-04 0,01424194 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 7,081E-04 0,01443737 ! regulation of survival gene product expression GO:0045884 33 17 1,000 7,081E-04 0,01431605 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 7,081E-04 0,01419675 ! genitalia development GO:0048806 30 17 1,000 7,081E-04 0,01407942 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 7,081E-04 0,01396401 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 7,081E-04 0,01385049 ! meiotic cell cycle GO:0051321 122 75 2,000 7,202E-04 0,01397466 ! development of primary sexual characteristics GO:0045137 124 76 2,000 7,486E-04 0,01440864 ! regulation of catabolic process GO:0009894 161 76 2,000 7,486E-04 0,01429429 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 7,954E-04 0,01506837 ! memory GO:0007613 31 18 1,000 7,954E-04 0,01495065 ! regulation of peptidase activity GO:0052547 134 79 2,000 8,379E-04 0,01562742 ! regulation of postsynaptic membrane potential GO:0060078 32 19 1,000 8,876E-04 0,01642778 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 8,876E-04 0,01630237 ! pigmentation during development GO:0048066 41 19 1,000 8,876E-04 0,01617887 ! neuromuscular junction development GO:0007528 34 19 1,000 8,876E-04 0,01605723 ! visual learning GO:0008542 36 19 1,000 8,876E-04 0,0159374 ! cellular pigmentation GO:0033059 36 19 1,000 8,876E-04 0,01581934 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 8,876E-04 0,01570302 ! response to drug GO:0042493 143 82 2,000 9,337E-04 0,01639727 ! response to alkaloid GO:0043279 38 20 1,000 9,848E-04 0,01716912 ! cellular response to starvation GO:0009267 33 20 1,000 9,848E-04 0,0170456 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 9,848E-04 0,01692385 ! negative regulation of T cell activation GO:0050868 40 20 1,000 9,848E-04 0,01680382 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,848E-04 0,01668549 ! mitochondrion organization GO:0007005 148 86 2,000 1,072E-03 0,01803363 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 1,087E-03 0,01815842 ! cytolysis GO:0019835 24 21 1,000 1,087E-03 0,01803319 ! oogenesis GO:0048477 36 21 1,000 1,087E-03 0,01790968 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,087E-03 0,01778784 ! gland development GO:0048732 206 88 2,000 1,145E-03 0,01862177 ! regulation of cell adhesion GO:0030155 212 89 2,000 1,183E-03 0,01911033 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 1,194E-03 0,01914652 ! glutamate signaling pathway GO:0007215 41 22 1,000 1,194E-03 0,01901972 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,194E-03 0,01889459 ! apoptotic nuclear changes GO:0030262 32 22 1,000 1,194E-03 0,0187711 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 1,194E-03 0,01864921 ! sex differentiation GO:0007548 145 90 2,000 1,222E-03 0,01897257 ! regulation of cell cycle process GO:0010564 149 90 2,000 1,222E-03 0,01885095 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,305E-03 0,02000497 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,305E-03 0,01987835 ! visual behavior GO:0007632 42 23 1,000 1,305E-03 0,01975333 ! response to ethanol GO:0045471 46 23 1,000 1,305E-03 0,01962987 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 1,305E-03 0,01950795 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 1,305E-03 0,01938753 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,305E-03 0,01926859 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,305E-03 0,0191511 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 1,343E-03 0,01958897 ! regulation of membrane potential GO:0042391 164 93 2,000 1,343E-03 0,01947097 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,422E-03 0,02048602 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,422E-03 0,02036408 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 1,422E-03 0,02024358 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 1,422E-03 0,0201245 ! membrane depolarization GO:0051899 39 24 1,000 1,422E-03 0,02000682 ! protein tetramerization GO:0051262 52 24 1,000 1,422E-03 0,0198905 ! positive regulation of immune response GO:0050778 156 96 2,000 1,472E-03 0,02046923 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,543E-03 0,02133954 ! myelination GO:0042552 45 25 1,000 1,543E-03 0,0212176 ! response to starvation GO:0042594 42 25 1,000 1,543E-03 0,02109705 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,543E-03 0,02097786 ! negative regulation of cell development GO:0010721 73 25 1,000 1,543E-03 0,02086 GO:0050768|negative regulation of neurogenesis, ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,543E-03 0,02074347 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 1,669E-03 0,02231373 ! positive regulation of nuclear division GO:0051785 40 26 1,000 1,669E-03 0,02219045 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 1,669E-03 0,02206852 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,8E-03 0,02366822 ! base-excision repair GO:0006284 41 27 1,000 1,8E-03 0,02353959 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 1,8E-03 0,02341235 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,936E-03 0,02504015 ! regulation of pH GO:0006885 43 29 1,000 2,076E-03 0,02671106 ! catechol metabolic process GO:0009712 54 29 1,000 2,076E-03 0,02656898 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 1,000 2,076E-03 0,0264284 ! immune response-activating signal transduction GO:0002757 47 29 1,000 2,076E-03 0,0262893 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 1,000 2,076E-03 0,02615166 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,076E-03 0,02601546 ! tissue homeostasis GO:0001894 48 29 1,000 2,076E-03 0,02588066 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 1,000 2,221E-03 0,027545 ! ensheathment of neurons GO:0007272 57 30 1,000 2,221E-03 0,02740375 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,221E-03 0,02726393 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 2,371E-03 0,02895281 ! spindle organization GO:0007051 46 32 1,000 2,525E-03 0,03068099 ! response to mechanical stimulus GO:0009612 57 32 1,000 2,525E-03 0,03052682 ! peripheral nervous system development GO:0007422 64 32 1,000 2,525E-03 0,03037418 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,525E-03 0,03022307 ! DNA damage checkpoint GO:0000077 71 33 1,000 2,684E-03 0,03196572 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 2,684E-03 0,03180825 ! negative regulation of protein transport GO:0051224 69 33 1,000 2,684E-03 0,03165233 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 3,015E-03 0,03538859 ! odontogenesis GO:0042476 66 35 1,000 3,015E-03 0,03521681 ! female gonad development GO:0008585 58 35 1,000 3,015E-03 0,03504668 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 3,015E-03 0,03487818 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 3,188E-03 0,03669812 ! DNA integrity checkpoint GO:0031570 75 36 1,000 3,188E-03 0,03652336 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,188E-03 0,03635027 ! meiosis I GO:0007127 65 37 1,000 3,365E-03 0,03818891 ! sister chromatid segregation GO:0000819 58 37 1,000 3,365E-03 0,03800962 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 3,365E-03 0,03783201 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 3,547E-03 0,03968856 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 3,547E-03 0,03950481 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 3,547E-03 0,03932276 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 3,547E-03 0,03914239 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 3,547E-03 0,03896365 ! ear morphogenesis GO:0042471 60 39 1,000 3,733E-03 0,04082194 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 3,733E-03 0,04063722 ! regulation of action potential in neuron GO:0019228 73 39 1,000 3,733E-03 0,04045417 ! feeding behavior GO:0007631 59 40 1,000 3,923E-03 0,04232896 ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,118E-03 0,04423474 ! T cell differentiation GO:0030217 81 41 1,000 4,118E-03 0,04403815 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,118E-03 0,04384329 ! female gamete generation GO:0007292 61 41 1,000 4,118E-03 0,04365014 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 4,318E-03 0,04556338 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 4,318E-03 0,04536441 ! male sex differentiation GO:0046661 76 44 1,000 4,73E-03 0,04947789 ! B cell differentiation GO:0030183 107 44 1,000 4,73E-03 0,0492637 ! developmental growth GO:0048589 82 44 1,000 4,73E-03 0,04905136 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 4,942E-03 0,0510361 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 5,159E-03 0,0530485 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 5,159E-03 0,05282276 ! negative regulation of cell migration GO:0030336 115 46 1,000 5,159E-03 0,05259893 ! endosome transport GO:0016197 108 47 1,000 5,381E-03 0,05462311 ! mitochondrial transport GO:0006839 82 48 1,000 5,606E-03 0,05667374 ! cellular component disassembly GO:0022411 86 48 1,000 5,606E-03 0,05643661 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 5,606E-03 0,05620145 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 5,606E-03 0,05596825 ! regulation of action potential GO:0001508 95 49 1,000 5,836E-03 0,05802196 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 5,836E-03 0,05778318 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 5,836E-03 0,05754637 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 5,836E-03 0,05731149 ! neuromuscular process GO:0050905 99 50 1,000 6,07E-03 0,05936798 ! negative regulation of immune system process GO:0002683 95 50 1,000 6,07E-03 0,05912762 ! response to estrogen stimulus GO:0043627 93 51 1,000 6,308E-03 0,06120131 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 6,308E-03 0,06095552 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 6,308E-03 0,0607117 ! regulation of angiogenesis GO:0045765 114 52 1,000 6,551E-03 0,06279471 ! synapse organization GO:0050808 85 52 1,000 6,551E-03 0,06254552 ! cell maturation GO:0048469 100 53 1,000 6,798E-03 0,06464473 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 6,798E-03 0,06439022 ! nuclear export GO:0051168 97 55 1,000 7,304E-03 0,06891176 ! negative regulation of cell motion GO:0051271 134 55 1,000 7,304E-03 0,06864257 ! skeletal muscle fiber development GO:0048741 111 56 1,000 7,563E-03 0,0708021 ! positive regulation of organelle organization GO:0010638 100 56 1,000 7,563E-03 0,07052768 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 7,826E-03 0,07270149 ! muscle fiber development GO:0048747 112 57 1,000 7,826E-03 0,07242187 ! regulation of intracellular transport GO:0032386 101 57 1,000 7,826E-03 0,07214439 ! skeletal system morphogenesis GO:0048705 105 59 1,000 8,365E-03 0,0768179 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 8,365E-03 0,07652582 ! DNA catabolic process GO:0006308 86 59 1,000 8,365E-03 0,07623594 ! establishment of organelle localization GO:0051656 109 59 1,000 8,365E-03 0,07594826 ! ear development GO:0043583 103 62 1,000 9,204E-03 0,08324913 ! gonad development GO:0008406 98 62 1,000 9,204E-03 0,08293734 ! regulation of mitosis GO:0007088 105 63 1,000 9,491E-03 0,0852098 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 9,491E-03 0,08489303 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 9,783E-03 0,08717686 ! single fertilization GO:0007338 75 64 1,000 9,783E-03 0,08685517 ! germ cell development GO:0007281 118 65 1,000 0,01007847 0,08915001 ! actin filament organization GO:0007015 148 66 1,000 0,01037794 0,09146274 ! extracellular matrix organization GO:0030198 133 66 1,000 0,01037794 0,09112893 ! developmental maturation GO:0021700 116 66 1,000 0,01037794 0,09079755 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01068133 0,09311334 ! lung development GO:0030324 144 67 1,000 0,01068133 0,09277719 ! chromosome segregation GO:0007059 113 67 1,000 0,01068133 0,09244346 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01068133 0,09211212 ! adaptive immune response GO:0002250 119 67 1,000 0,01068133 0,09178315 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,01098862 0,09408761 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01129979 0,09640884 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01129979 0,09606818 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01156821 0,09800393 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01156821 0,09766006 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01156821 0,09731859 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01156821 0,0969795 ! neuron fate determination GO:0048664 7 5 0,000 0,01156821 0,09664276 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01156821 0,09630836 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01156821 0,09597626 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01156821 0,09564645 ! polyol transport GO:0015791 12 5 0,000 0,01156821 0,09531889 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01156821 0,09499357 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01156821 0,09467046 ! response to superoxide GO:0000303 10 5 0,000 0,01156821 0,09434955 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01156821 0,0940308 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01156821 0,0937142 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01156821 0,09339972 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01156821 0,09308735 ! female meiosis GO:0007143 7 5 0,000 0,01156821 0,09277705 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01156821 0,09246882 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01156821 0,09216264 ! cobalt ion transport GO:0006824 11 5 0,000 0,01156821 0,09185847 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01156821 0,0915563 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01156821 0,09125612 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01156821 0,0909579 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01156821 0,09066162 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01156821 0,09036726 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01156821 0,09007481 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01156821 0,08978425 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01156821 0,08949555 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01156821 0,08920871 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01156821 0,08892369 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01156821 0,0886405 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01156821 0,0883591 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01156821 0,08807948 ! negative chemotaxis GO:0050919 14 5 0,000 0,01156821 0,08780163 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01156821 0,08752552 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01156821 0,08725115 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01156821 0,08697849 ! behavioral response to pain GO:0048266 9 5 0,000 0,01156821 0,08670753 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01156821 0,08643825 ! Notch receptor processing GO:0007220 8 5 0,000 0,01156821 0,08617064 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01156821 0,08590468 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01156821 0,08564036 ! micturition GO:0060073 9 5 0,000 0,01156821 0,08537766 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01156821 0,08511656 ! copulation GO:0007620 9 5 0,000 0,01156821 0,08485706 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01156821 0,08459914 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01156821 0,08434278 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01156821 0,08408796 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01156821 0,08383469 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01156821 0,08358293 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01156821 0,08333268 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01156821 0,08308393 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01156821 0,08283666 ! grooming behavior GO:0007625 6 5 0,000 0,01156821 0,08259085 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01156821 0,0823465 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01156821 0,08210359 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01156821 0,08186211 ! response to protozoan GO:0001562 10 5 0,000 0,01156821 0,08162204 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01156821 0,08138338 ! lymph vessel development GO:0001945 10 5 0,000 0,01156821 0,08114611 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01156821 0,08091022 ! endochondral ossification GO:0001958 16 5 0,000 0,01156821 0,0806757 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01156821 0,08044253 ! parathyroid gland development GO:0060017 13 5 0,000 0,01156821 0,08021071 ! anagen GO:0042640 6 5 0,000 0,01156821 0,07998022 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01156821 0,07975105 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01156821 0,07952319 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01156821 0,07929663 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01156821 0,07907135 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01156821 0,07884735 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01156821 0,07862462 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01156821 0,07840314 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01156821 0,07818291 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01156821 0,07796391 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01156821 0,07774613 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01156821 0,07752957 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01156821 0,07731421 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01156821 0,07710005 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01156821 0,07688706 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01156821 0,07667525 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01156821 0,07646461 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01156821 0,07625511 ! histidine catabolic process GO:0006548 6 5 0,000 0,01156821 0,07604677 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01156821 0,07583955 ! microvillus organization GO:0032528 7 5 0,000 0,01156821 0,07563347 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01156821 0,0754285 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01156821 0,07522464 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01156821 0,07502188 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01156821 0,07482021 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01156821 0,07461961 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01156821 0,0744201 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01156821 0,07422164 ! polyol catabolic process GO:0046174 7 5 0,000 0,01156821 0,07402425 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01156821 0,07382789 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01156821 0,07363258 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01156821 0,0734383 ! muscle cell migration GO:0014812 8 5 0,000 0,01156821 0,07324504 ! mitochondrial fission GO:0000266 8 5 0,000 0,01156821 0,0730528 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01156821 0,07286156 ! mRNA transcription GO:0009299 9 5 0,000 0,01156821 0,07267132 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01156821 0,07248207 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01156821 0,07229381 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01156821 0,07210652 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01156821 0,0719202 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01156821 0,07173484 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01156821 0,07155043 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01156821 0,07136696 ! response to food GO:0032094 6 5 0,000 0,01156821 0,07118444 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01156821 0,07100285 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01156821 0,07082218 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01156821 0,07064243 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01156821 0,07046359 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01156821 0,07028565 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01156821 0,07010861 ! forebrain neuron development GO:0021884 13 5 0,000 0,01156821 0,06993245 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01156821 0,06975718 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01156821 0,06958279 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01156821 0,06940927 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01156821 0,06923661 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01156821 0,0690648 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01156821 0,06889385 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01156821 0,06872374 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01156821 0,06855447 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01156821 0,06838604 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01156821 0,06821842 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01156821 0,06805163 ! basic amino acid transport GO:0015802 11 5 0,000 0,01156821 0,06788565 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01156821 0,06772048 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01156821 0,06755611 ! depyrimidination GO:0045008 10 5 0,000 0,01156821 0,06739253 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01156821 0,06722975 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01156821 0,06706775 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01156821 0,06690653 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01156821 0,06674608 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01156821 0,0665864 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01156821 0,06642749 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01156821 0,06626932 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01156821 0,06611192 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01156821 0,06595525 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01156821 0,06579933 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01156821 0,06564414 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01156821 0,06548969 ! response to arsenic GO:0046685 10 5 0,000 0,01156821 0,06533595 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01156821 0,06518294 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01156821 0,06503065 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01156821 0,06487906 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01156821 0,06472818 ! response to cadmium ion GO:0046686 7 5 0,000 0,01156821 0,064578 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01156821 0,06442851 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01156821 0,06427971 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01156821 0,0641316 ! decidualization GO:0046697 11 5 0,000 0,01156821 0,06398418 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01156821 0,06383742 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01156821 0,06369134 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01156821 0,06354593 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01156821 0,06340118 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01156821 0,06325708 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01156821 0,06311364 ! neural tube patterning GO:0021532 7 5 0,000 0,01156821 0,06297085 ! embryonic cleavage GO:0040016 6 5 0,000 0,01156821 0,0628287 ! peroxisome fission GO:0016559 5 5 0,000 0,01156821 0,0626872 ! histone demethylation GO:0016577 10 5 0,000 0,01156821 0,06254633 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01156821 0,06240609 ! mitotic recombination GO:0006312 9 5 0,000 0,01156821 0,06226648 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01156821 0,06212749 ! metaphase plate congression GO:0051310 7 5 0,000 0,01156821 0,06198912 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01156821 0,06185137 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01156821 0,06171423 ! enteric nervous system development GO:0048484 8 5 0,000 0,01156821 0,06157769 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01156821 0,06144176 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01156821 0,06130642 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01156821 0,06117168 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01156821 0,06103754 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01156821 0,06090397 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01156821 0,060771 ! plasminogen activation GO:0031639 5 5 0,000 0,01156821 0,0606386 ! B cell homeostasis GO:0001782 13 5 0,000 0,01156821 0,06050677 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01156821 0,06037552 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01156821 0,06024484 ! metaphase GO:0051323 8 5 0,000 0,01156821 0,06011472 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01156821 0,05998516 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01156821 0,05985616 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01156821 0,05972772 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01156821 0,05959982 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01156821 0,05947247 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01156821 0,05934566 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01156821 0,0592194 ! response to redox state GO:0051775 5 5 0,000 0,01156821 0,05909367 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01156821 0,05896847 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01156821 0,0588438 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01156821 0,05871965 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01156821 0,05859603 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01156821 0,05847293 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01156821 0,05835035 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01156821 0,05822828 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01156821 0,05810671 ! striatum development GO:0021756 9 5 0,000 0,01156821 0,05798566 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01156821 0,05786511 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01156821 0,05774505 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01156821 0,0576255 ! glial cell migration GO:0008347 11 5 0,000 0,01156821 0,05750644 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01156821 0,05738787 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01156821 0,05726979 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01156821 0,05715219 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01156821 0,05703507 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01156821 0,05691844 ! neuroprotection GO:0043526 6 5 0,000 0,01156821 0,05680228 ! neural plate development GO:0001840 8 5 0,000 0,01156821 0,05668659 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01156821 0,05657137 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01156821 0,05645663 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01156821 0,05634234 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01156821 0,05622852 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01156821 0,05611515 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01156821 0,05600225 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01156821 0,05588979 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01156821 0,05577779 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01156821 0,05566623 ! spindle assembly GO:0051225 6 5 0,000 0,01156821 0,05555512 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01156821 0,05544445 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01156821 0,05533423 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01156821 0,05522444 ! drug metabolic process GO:0017144 6 5 0,000 0,01156821 0,05511508 ! stem cell division GO:0017145 11 5 0,000 0,01156821 0,05500616 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01156821 0,05489767 ! organ regeneration GO:0031100 7 5 0,000 0,01156821 0,0547896 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01156821 0,05468196 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01156821 0,05457474 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01156821 0,05446794 ! respiratory tube development GO:0030323 150 70 1,000 0,01161482 0,05458058 ! reproductive structure development GO:0048608 113 71 1,000 0,01193369 0,05596973 ! humoral immune response GO:0006959 109 71 1,000 0,01193369 0,05586084 ! B cell activation GO:0042113 160 71 1,000 0,01193369 0,05575237 ! acute inflammatory response GO:0002526 113 72 1,000 0,01225639 0,05714899 ! respiratory system development GO:0060541 153 72 1,000 0,01225639 0,05703845 ! axon guidance GO:0007411 139 73 1,000 0,01258289 0,05844487 ! fertilization GO:0009566 90 73 1,000 0,01258289 0,05833226 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,01291318 0,05974829 ! organelle localization GO:0051640 136 74 1,000 0,01291318 0,05963361 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01324723 0,06105909 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01324723 0,06094234 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01386597 0,06366705 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01386597 0,06354578 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01386597 0,06342497 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01386597 0,06330462 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01386597 0,06318472 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01386597 0,06306528 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01386597 0,06294629 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01386597 0,06282775 ! response to oxygen radical GO:0000305 11 6 0,000 0,01386597 0,06270965 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01386597 0,06259199 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01386597 0,06247478 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01386597 0,06235801 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01386597 0,06224167 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01386597 0,06212576 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01386597 0,06201028 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01386597 0,06189524 ! forebrain regionalization GO:0021871 8 6 0,000 0,01386597 0,06178062 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01386597 0,06166642 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01386597 0,06155264 ! response to zinc ion GO:0010043 9 6 0,000 0,01386597 0,06143929 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01386597 0,06132635 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01386597 0,06121382 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01386597 0,06110171 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01386597 0,06099001 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01386597 0,06087871 ! malate metabolic process GO:0006108 11 6 0,000 0,01386597 0,06076782 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01386597 0,06065733 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01386597 0,06054725 ! protein refolding GO:0042026 15 6 0,000 0,01386597 0,06043756 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01386597 0,06032827 ! opsonization GO:0008228 8 6 0,000 0,01386597 0,06021937 ! mating behavior GO:0007617 7 6 0,000 0,01386597 0,06011087 ! neuron remodeling GO:0016322 15 6 0,000 0,01386597 0,06000276 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01386597 0,05989503 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01386597 0,05978769 ! equilibrioception GO:0050957 14 6 0,000 0,01386597 0,05968074 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01386597 0,05957417 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01386597 0,05946797 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01386597 0,05936216 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01386597 0,05925672 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01386597 0,05915165 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01386597 0,05904696 ! toxin metabolic process GO:0009404 11 6 0,000 0,01386597 0,05894264 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01386597 0,05883868 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01386597 0,05873509 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01386597 0,05863187 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01386597 0,05852901 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01386597 0,0584265 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01386597 0,05832436 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01386597 0,05822257 ! thymic T cell selection GO:0045061 12 6 0,000 0,01386597 0,05812114 ! protein lipoylation GO:0009249 10 6 0,000 0,01386597 0,05802006 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01386597 0,05791933 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01386597 0,05781895 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01386597 0,05771892 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01386597 0,05761923 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01386597 0,05751988 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01386597 0,05742088 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01386597 0,05732222 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01386597 0,0572239 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01386597 0,05712591 ! hyperosmotic response GO:0006972 9 6 0,000 0,01386597 0,05702826 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01386597 0,05693094 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01386597 0,05683396 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01386597 0,0567373 ! urea metabolic process GO:0019627 7 6 0,000 0,01386597 0,05664097 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01386597 0,05654497 ! neutrophil activation GO:0042119 8 6 0,000 0,01386597 0,05644929 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01386597 0,05635394 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01386597 0,05625891 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01386597 0,0561642 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01386597 0,0560698 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01386597 0,05597573 ! neuron apoptosis GO:0051402 9 6 0,000 0,01386597 0,05588196 ! nucleoside salvage GO:0043174 9 6 0,000 0,01386597 0,05578852 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01386597 0,05569538 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01386597 0,05560255 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01386597 0,05551004 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01386597 0,05541783 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01386597 0,05532593 ! carnitine transport GO:0015879 10 6 0,000 0,01386597 0,05523433 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01386597 0,05514303 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01386597 0,05505203 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01386597 0,05496134 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01386597 0,05487094 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01386597 0,05478084 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01386597 0,05469104 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01386597 0,05460153 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01386597 0,05451231 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01386597 0,05442338 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01386597 0,05433474 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01386597 0,0542464 ! neural nucleus development GO:0048857 14 6 0,000 0,01386597 0,05415833 ! astrocyte development GO:0014002 15 6 0,000 0,01386597 0,05407056 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01386597 0,05398306 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01386597 0,05389585 ! interaction with symbiont GO:0051702 13 6 0,000 0,01386597 0,05380892 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01386597 0,05372228 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01386597 0,05363591 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01386597 0,05354981 ! response to copper ion GO:0046688 10 6 0,000 0,01386597 0,053464 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01386597 0,05337845 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01386597 0,05329318 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01386597 0,05320819 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01386597 0,05312346 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01386597 0,053039 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01386597 0,05295481 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01386597 0,05287089 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01386597 0,05278724 ! hair follicle maturation GO:0048820 7 6 0,000 0,01386597 0,05270384 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01386597 0,05262071 ! Schwann cell development GO:0014044 15 6 0,000 0,01386597 0,05253785 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01386597 0,05245524 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01386597 0,05237289 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01386597 0,0522908 ! subpallium development GO:0021544 10 6 0,000 0,01386597 0,05220897 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01386597 0,0521274 ! histone ubiquitination GO:0016574 8 6 0,000 0,01386597 0,05204607 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01386597 0,051965 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01386597 0,05188419 ! G2 phase GO:0051319 16 6 0,000 0,01386597 0,05180362 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01386597 0,05172331 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01386597 0,05164324 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01386597 0,05156342 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01386597 0,05148385 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01386597 0,05140452 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01386597 0,05132544 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01386597 0,05124659 ! receptor internalization GO:0031623 10 6 0,000 0,01386597 0,051168 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01386597 0,05108964 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01386597 0,05101152 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01386597 0,05093364 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01386597 0,050856 ! protein deubiquitination GO:0016579 14 6 0,000 0,01386597 0,05077859 ! protein destabilization GO:0031648 9 6 0,000 0,01386597 0,05070142 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01386597 0,05062448 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01386597 0,05054778 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01386597 0,05047131 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01386597 0,05039506 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01386597 0,05031905 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01386597 0,05024327 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01386597 0,05016772 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01386597 0,05009239 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01386597 0,05001729 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01386597 0,04994241 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01386597 0,04986776 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01386597 0,04979333 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01386597 0,04971913 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01386597 0,04964514 ! catecholamine transport GO:0051937 9 6 0,000 0,01386597 0,04957137 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01386597 0,04949782 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01386597 0,04942449 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01386597 0,04935138 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01386597 0,04927848 ! maternal placenta development GO:0001893 12 6 0,000 0,01386597 0,0492058 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01386597 0,04913333 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01386597 0,04906108 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01386597 0,04898904 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01386597 0,0489172 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01386597 0,04884558 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01386597 0,04877417 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01386597 0,04870297 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,01427181 0,05005535 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,01427181 0,04998249 ! protein oligomerization GO:0051259 139 78 1,000 0,01427181 0,04990984 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,01462074 0,05105588 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,01462074 0,05098189 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,01462074 0,05090811 ! protein import into nucleus GO:0006606 158 80 1,000 0,01497335 0,05206051 ! T cell activation GO:0042110 168 81 1,000 0,01532961 0,05322228 ! nuclear import GO:0051170 161 81 1,000 0,01532961 0,05314559 ! response to nutrient GO:0007584 125 82 1,000 0,01568951 0,05431504 ! tRNA transcription GO:0009304 14 7 0,000 0,01615847 0,05585816 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01615847 0,05577802 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01615847 0,05569811 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01615847 0,05561843 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01615847 0,05553897 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01615847 0,05545974 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01615847 0,05538074 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01615847 0,05530196 ! prostate gland development GO:0030850 13 7 0,000 0,01615847 0,05522341 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01615847 0,05514508 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01615847 0,05506697 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01615847 0,05498908 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01615847 0,05491141 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01615847 0,05483396 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01615847 0,05475673 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01615847 0,05467972 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01615847 0,05460292 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01615847 0,05452634 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01615847 0,05444997 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01615847 0,05437382 ! glycolipid transport GO:0046836 10 7 0,000 0,01615847 0,05429788 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01615847 0,05422215 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01615847 0,05414663 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01615847 0,05407132 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01615847 0,05399622 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01615847 0,05392133 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01615847 0,05384665 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01615847 0,05377217 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01615847 0,0536979 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01615847 0,05362384 ! mRNA stabilization GO:0048255 18 7 0,000 0,01615847 0,05354997 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01615847 0,05347632 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01615847 0,05340286 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01615847 0,0533296 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01615847 0,05325655 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01615847 0,0531837 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01615847 0,05311104 ! lipoprotein transport GO:0042953 14 7 0,000 0,01615847 0,05303858 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01615847 0,05296632 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01615847 0,05289426 ! rhythmic behavior GO:0007622 15 7 0,000 0,01615847 0,05282239 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01615847 0,05275072 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01615847 0,05267924 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01615847 0,05260796 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01615847 0,05253687 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01615847 0,05246597 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01615847 0,05239526 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01615847 0,05232474 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01615847 0,05225441 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01615847 0,05218427 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01615847 0,05211432 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01615847 0,05204455 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01615847 0,05197497 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01615847 0,05190558 ! spinal cord patterning GO:0021511 13 7 0,000 0,01615847 0,05183637 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01615847 0,05176735 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01615847 0,05169851 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01615847 0,05162986 ! adrenal gland development GO:0030325 17 7 0,000 0,01615847 0,05156138 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01615847 0,05149309 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01615847 0,05142498 ! ovulation GO:0030728 9 7 0,000 0,01615847 0,05135704 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01615847 0,05128929 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01615847 0,05122171 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01615847 0,05115432 ! microtubule nucleation GO:0007020 20 7 0,000 0,01615847 0,0510871 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01615847 0,05102005 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01615847 0,05095319 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01615847 0,05088649 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01615847 0,05081998 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01615847 0,05075363 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01615847 0,05068746 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01615847 0,05062146 ! galactose metabolic process GO:0006012 13 7 0,000 0,01615847 0,05055563 ! vesicle fusion GO:0006906 17 7 0,000 0,01615847 0,05048998 ! response to dietary excess GO:0002021 8 7 0,000 0,01615847 0,05042449 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01615847 0,05035917 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01615847 0,05029402 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01615847 0,05022905 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01615847 0,05016423 ! organ growth GO:0035265 15 7 0,000 0,01615847 0,05009959 ! purine salvage GO:0043101 10 7 0,000 0,01615847 0,05003511 ! nucleoside transport GO:0015858 8 7 0,000 0,01615847 0,0499708 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01615847 0,04990665 ! parturition GO:0007567 14 7 0,000 0,01615847 0,04984267 ! rRNA modification GO:0000154 14 7 0,000 0,01615847 0,04977885 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01615847 0,04971519 ! spindle checkpoint GO:0031577 15 7 0,000 0,01615847 0,0496517 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01615847 0,04958837 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01615847 0,0495252 ! macrophage differentiation GO:0030225 11 7 0,000 0,01615847 0,04946219 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01615847 0,04939934 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01615847 0,04933665 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01615847 0,04927412 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01615847 0,04921175 ! fibrinolysis GO:0042730 10 7 0,000 0,01615847 0,04914953 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01615847 0,04908748 ! eating behavior GO:0042755 7 7 0,000 0,01615847 0,04902558 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01615847 0,04896383 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01615847 0,04890224 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01615847 0,04884081 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01615847 0,04877952 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01615847 0,0487184 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01615847 0,04865742 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01615847 0,0485966 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01615847 0,04853593 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01615847 0,04847541 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01615847 0,04841504 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01615847 0,04835483 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01615847 0,04829476 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01615847 0,04823484 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01615847 0,04817507 ! regulation of meiosis GO:0040020 12 7 0,000 0,01615847 0,04811545 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01615847 0,04805597 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01615847 0,04799664 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01615847 0,04793746 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01615847 0,04787843 ! transcription termination GO:0006353 13 7 0,000 0,01615847 0,04781953 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01615847 0,04776079 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01615847 0,04770219 ! anaphase GO:0051322 17 7 0,000 0,01615847 0,04764373 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01615847 0,04758541 ! axonal fasciculation GO:0007413 18 7 0,000 0,01615847 0,04752724 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01615847 0,04746921 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01615847 0,04741132 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01615847 0,04735357 ! diuresis GO:0030146 12 7 0,000 0,01615847 0,04729596 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01615847 0,04723849 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01615847 0,04718117 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01615847 0,04712398 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01615847 0,04706693 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01615847 0,04701001 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01615847 0,04695324 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01615847 0,0468966 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01615847 0,0468401 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01615847 0,04678373 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01615847 0,0467275 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01615847 0,04667141 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01615847 0,04661544 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01615847 0,04655962 ! lymph node development GO:0048535 10 7 0,000 0,01615847 0,04650392 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01615847 0,04644836 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01615847 0,04639294 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01615847 0,04633764 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01615847 0,04628248 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01615847 0,04622744 ! adult feeding behavior GO:0008343 9 7 0,000 0,01615847 0,04617254 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01615847 0,04611777 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01615847 0,04606313 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01615847 0,04600862 ! muscle adaptation GO:0043500 14 7 0,000 0,01615847 0,04595423 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01615847 0,04589998 ! retina homeostasis GO:0001895 12 7 0,000 0,01615847 0,04584585 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01615847 0,04579185 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01615847 0,04573798 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01615847 0,04568423 ! protein prenylation GO:0018342 18 7 0,000 0,01615847 0,04563061 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01615847 0,04557712 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01615847 0,04552375 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01615847 0,0454705 ! negative regulation of transport GO:0051051 153 84 1,000 0,01642014 0,04615287 ! negative regulation of growth GO:0045926 155 84 1,000 0,01642014 0,04609902 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,01642014 0,04604529 ! protein localization in nucleus GO:0034504 176 87 1,000 0,01754291 0,04913648 ! regulation of protein transport GO:0051223 154 87 1,000 0,01754291 0,04907935 GO:0070201|regulation of establishment of protein localization, ! regulation of neurological system process GO:0031644 148 88 1,000 0,01792424 0,05008796 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,01830909 0,05110403 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01844571 0,05142571 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01844571 0,05136619 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01844571 0,05130681 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01844571 0,05124756 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01844571 0,05118845 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01844571 0,05112948 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01844571 0,05107064 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01844571 0,05101194 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01844571 0,05095337 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01844571 0,05089494 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01844571 0,05083664 ! meiotic prophase I GO:0007128 13 8 0,000 0,01844571 0,05077848 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01844571 0,05072045 ! oligopeptide transport GO:0006857 15 8 0,000 0,01844571 0,05066254 ! UTP metabolic process GO:0046051 8 8 0,000 0,01844571 0,05060478 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01844571 0,05054714 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01844571 0,05048964 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01844571 0,05043226 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01844571 0,05037502 ! succinate metabolic process GO:0006105 14 8 0,000 0,01844571 0,0503179 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01844571 0,05026092 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01844571 0,05020406 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01844571 0,05014733 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01844571 0,05009073 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01844571 0,05003426 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01844571 0,04997792 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01844571 0,0499217 ! reflex GO:0060004 16 8 0,000 0,01844571 0,04986561 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01844571 0,04980964 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01844571 0,0497538 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01844571 0,04969808 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01844571 0,04964249 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01844571 0,04958703 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01844571 0,04953168 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01844571 0,04947647 ! pigment granule organization GO:0048753 16 8 0,000 0,01844571 0,04942137 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01844571 0,0493664 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01844571 0,04931154 ! histidine metabolic process GO:0006547 16 8 0,000 0,01844571 0,04925681 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01844571 0,04920221 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01844571 0,04914772 ! glycine catabolic process GO:0006546 13 8 0,000 0,01844571 0,04909335 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01844571 0,0490391 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01844571 0,04898498 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01844571 0,04893097 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01844571 0,04887708 ! melanin metabolic process GO:0006582 15 8 0,000 0,01844571 0,04882331 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01844571 0,04876966 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01844571 0,04871612 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01844571 0,04866271 ! macrophage activation GO:0042116 12 8 0,000 0,01844571 0,04860941 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01844571 0,04855622 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01844571 0,04850316 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01844571 0,04845021 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01844571 0,04839737 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01844571 0,04834465 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01844571 0,04829205 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01844571 0,04823955 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01844571 0,04818718 ! osteoblast development GO:0002076 16 8 0,000 0,01844571 0,04813491 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01844571 0,04808276 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01844571 0,04803072 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01844571 0,0479788 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01844571 0,04792699 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01844571 0,04787529 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01844571 0,0478237 ! response to UV-B GO:0010224 16 8 0,000 0,01844571 0,04777222 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01844571 0,04772085 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01844571 0,04766959 ! intermediate filament organization GO:0045109 12 8 0,000 0,01844571 0,04761844 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01844571 0,04756741 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01844571 0,04751648 ! cellular extravasation GO:0045123 12 8 0,000 0,01844571 0,04746566 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01844571 0,04741495 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01844571 0,04736434 ! response to antibiotic GO:0046677 11 8 0,000 0,01844571 0,04731385 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01844571 0,04726346 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01844571 0,04721318 ! DNA topological change GO:0006265 12 8 0,000 0,01844571 0,04716301 ! response to tropane GO:0014073 15 8 0,000 0,01844571 0,04711294 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01844571 0,04706298 ! melanosome transport GO:0032402 13 8 0,000 0,01844571 0,04701312 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01844571 0,04696338 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01844571 0,04691373 ! mast cell activation GO:0045576 14 8 0,000 0,01844571 0,04686419 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01844571 0,04681476 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01844571 0,04676543 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01844571 0,0467162 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01844571 0,04666708 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01844571 0,04661806 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01844571 0,04656914 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01844571 0,04652032 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01844571 0,04647161 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01844571 0,046423 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01844571 0,04637449 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01844571 0,04632608 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01844571 0,04627778 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01844571 0,04622957 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01844571 0,04618147 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01844571 0,04613346 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01844571 0,04608555 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01844571 0,04603775 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01844571 0,04599004 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01844571 0,04594243 ! hormone catabolic process GO:0042447 17 8 0,000 0,01844571 0,04589492 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01844571 0,04584751 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01844571 0,0458002 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01844571 0,04575298 ! ATP catabolic process GO:0006200 11 8 0,000 0,01844571 0,04570586 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01844571 0,04565884 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01844571 0,04561191 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01844571 0,04556508 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01844571 0,04551835 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01844571 0,04547171 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01844571 0,04542517 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01844571 0,04537872 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01844571 0,04533237 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01844571 0,04528611 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01844571 0,04523995 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01844571 0,04519388 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01844571 0,0451479 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01844571 0,04510202 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01844571 0,04505623 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01844571 0,04501054 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01844571 0,04496493 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01844571 0,04491942 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,02028534 0,04934937 ! transcription initiation GO:0006352 153 94 1,000 0,02028534 0,04929952 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02028534 0,04924977 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,02069087 0,0501837 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02072772 0,05022244 ! axon extension GO:0048675 15 9 0,000 0,02072772 0,05017192 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02072772 0,05012149 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02072772 0,05007117 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02072772 0,05002095 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02072772 0,04997083 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02072772 0,04992081 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02072772 0,04987089 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02072772 0,04982107 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02072772 0,04977134 ! phosphate transport GO:0006817 19 9 0,000 0,02072772 0,04972172 ! reproductive behavior GO:0019098 19 9 0,000 0,02072772 0,0496722 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02072772 0,04962277 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02072772 0,04957345 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02072772 0,04952422 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 0,000 0,02072772 0,04947509 ! RNA methylation GO:0001510 15 9 0,000 0,02072772 0,04942605 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02072772 0,04937712 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02072772 0,04932828 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02072772 0,04927953 ! artery development GO:0060840 24 9 0,000 0,02072772 0,04923088 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02072772 0,04918233 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02072772 0,04913388 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02072772 0,04908552 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02072772 0,04903725 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02072772 0,04898908 ! chemosensory behavior GO:0007635 20 9 0,000 0,02072772 0,04894101 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02072772 0,04889303 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02072772 0,04884514 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02072772 0,04879734 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02072772 0,04874964 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02072772 0,04870204 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02072772 0,04865452 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02072772 0,0486071 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02072772 0,04855977 ! protein targeting to ER GO:0045047 22 9 0,000 0,02072772 0,04851254 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02072772 0,04846539 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02072772 0,04841834 ! T cell selection GO:0045058 23 9 0,000 0,02072772 0,04837137 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02072772 0,0483245 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02072772 0,04827772 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02072772 0,04823103 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02072772 0,04818443 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02072772 0,04813792 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02072772 0,0480915 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02072772 0,04804517 ! mannose metabolic process GO:0006013 13 9 0,000 0,02072772 0,04799893 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02072772 0,04795278 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02072772 0,04790671 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02072772 0,04786074 ! receptor clustering GO:0043113 18 9 0,000 0,02072772 0,04781485 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02072772 0,04776905 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02072772 0,04772334 ! ruffle organization GO:0031529 15 9 0,000 0,02072772 0,04767771 ! retinol metabolic process GO:0042572 18 9 0,000 0,02072772 0,04763217 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02072772 0,04758672 ! behavioral fear response GO:0001662 22 9 0,000 0,02072772 0,04754136 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02072772 0,04749608 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02072772 0,04745089 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02072772 0,04740579 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,02072772 0,04736077 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02072772 0,04731583 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02072772 0,04727098 ! segment specification GO:0007379 13 9 0,000 0,02072772 0,04722622 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02072772 0,04718154 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02072772 0,04713694 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02072772 0,04709243 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02072772 0,04704801 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02072772 0,04700366 ! erythrocyte development GO:0048821 15 9 0,000 0,02072772 0,0469594 ! gas homeostasis GO:0033483 16 9 0,000 0,02072772 0,04691523 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02072772 0,04687113 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02072772 0,04682712 ! renal water homeostasis GO:0003091 14 9 0,000 0,02072772 0,0467832 ! postreplication repair GO:0006301 22 9 0,000 0,02072772 0,04673935 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02072772 0,04669559 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02072772 0,0466519 ! icosanoid secretion GO:0032309 15 9 0,000 0,02072772 0,0466083 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02072772 0,04656479 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02072772 0,04652135 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02072772 0,04647799 ! regulation of cell division GO:0051302 15 9 0,000 0,02072772 0,04643472 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02072772 0,04639152 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02072772 0,04634841 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02072772 0,04630537 ! sterol catabolic process GO:0016127 11 9 0,000 0,02072772 0,04626242 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02072772 0,04621954 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02072772 0,04617675 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02072772 0,04613403 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02072772 0,04609139 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02072772 0,04604883 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02072772 0,04600635 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02072772 0,04596395 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02072772 0,04592163 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02072772 0,04587938 ! purine base metabolic process GO:0006144 21 9 0,000 0,02072772 0,04583721 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02072772 0,04579512 ! pigment granule transport GO:0051904 17 9 0,000 0,02072772 0,04575311 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02072772 0,04571117 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02072772 0,04566931 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02072772 0,04562753 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02072772 0,04558582 ! mitochondrion localization GO:0051646 15 9 0,000 0,02072772 0,04554419 ! leukocyte differentiation GO:0002521 202 96 1,000 0,02109978 0,04631942 ! detection of stimulus GO:0051606 151 96 1,000 0,02109978 0,04627719 ! protein ubiquitination GO:0016567 217 97 1,000 0,02151207 0,04713847 ! regulation of protein localization GO:0032880 176 97 1,000 0,02151207 0,04709558 ! interphase GO:0051325 213 98 1,000 0,0219277 0,04796187 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,02234667 0,04883388 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02234667 0,04878956 GO:0060538|skeletal muscle organ development, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02300449 0,05018024 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02300449 0,05013478 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02300449 0,05008941 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02300449 0,05004412 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02300449 0,04999892 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02300449 0,04995379 ! synapsis GO:0007129 13 10 0,000 0,02300449 0,04990875 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02300449 0,04986378 ! N-glycan processing GO:0006491 20 10 0,000 0,02300449 0,0498189 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02300449 0,0497741 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02300449 0,04972938 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02300449 0,04968474 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02300449 0,04964018 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02300449 0,0495957 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02300449 0,0495513 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02300449 0,04950698 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02300449 0,04946273 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02300449 0,04941857 ! androgen metabolic process GO:0008209 17 10 0,000 0,02300449 0,04937449 ! phospholipid efflux GO:0033700 16 10 0,000 0,02300449 0,04933048 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02300449 0,04928655 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02300449 0,04924271 ! lung alveolus development GO:0048286 26 10 0,000 0,02300449 0,04919893 ! pathogenesis GO:0009405 13 10 0,000 0,02300449 0,04915524 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02300449 0,04911162 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02300449 0,04906809 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02300449 0,04902462 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02300449 0,04898124 ! endoderm development GO:0007492 16 10 0,000 0,02300449 0,04893793 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02300449 0,0488947 ! arginine catabolic process GO:0006527 13 10 0,000 0,02300449 0,04885154 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02300449 0,04880847 ! proline metabolic process GO:0006560 13 10 0,000 0,02300449 0,04876546 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02300449 0,04872254 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02300449 0,04867968 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02300449 0,04863691 ! V(D)J recombination GO:0033151 28 10 0,000 0,02300449 0,04859421 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02300449 0,04855158 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02300449 0,04850903 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02300449 0,04846655 ! B cell proliferation GO:0042100 18 10 0,000 0,02300449 0,04842415 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02300449 0,04838182 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02300449 0,04833956 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02300449 0,04829738 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02300449 0,04825528 ! epithelial cell development GO:0002064 20 10 0,000 0,02300449 0,04821324 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02300449 0,04817128 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02300449 0,04812939 ! macroautophagy GO:0016236 17 10 0,000 0,02300449 0,04808758 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02300449 0,04804583 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02300449 0,04800416 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02300449 0,04796257 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02300449 0,04792104 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02300449 0,04787959 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02300449 0,0478382 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02300449 0,04779689 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02300449 0,04775565 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02300449 0,04771448 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02300449 0,04767339 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02300449 0,04763236 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02300449 0,0475914 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02300449 0,04755052 ! response to dsRNA GO:0043331 20 10 0,000 0,02300449 0,0475097 ! DNA ligation GO:0006266 19 10 0,000 0,02300449 0,04746895 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02300449 0,04742828 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02300449 0,04738767 ! melanosome localization GO:0032400 16 10 0,000 0,02300449 0,04734713 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02300449 0,04730667 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02300449 0,04726627 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02300449 0,04722594 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02300449 0,04718568 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02300449 0,04714549 ! mRNA cleavage GO:0006379 17 10 0,000 0,02300449 0,04710536 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02300449 0,04706531 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02300449 0,04702532 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02300449 0,0469854 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02300449 0,04694555 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02300449 0,04690576 ! salivary gland development GO:0007431 27 10 0,000 0,02300449 0,04686605 ! prophase GO:0051324 15 10 0,000 0,02300449 0,0468264 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02300449 0,04678681 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02300449 0,0467473 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02300449 0,04670785 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02300449 0,04666847 ! midbrain development GO:0030901 13 10 0,000 0,02300449 0,04662915 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02300449 0,0465899 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02300449 0,04655072 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02300449 0,0465116 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02300449 0,04647254 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02300449 0,04643356 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02300449 0,04639464 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02300449 0,04635578 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02300449 0,04631699 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02300449 0,04627826 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02300449 0,0462396 ! blastocyst formation GO:0001825 17 10 0,000 0,02300449 0,046201 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02300449 0,04616247 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02300449 0,046124 ! activation of innate immune response GO:0002218 12 10 0,000 0,02300449 0,0460856 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02300449 0,04604725 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02300449 0,04600898 ! response to nicotine GO:0035094 20 10 0,000 0,02300449 0,04597076 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02300449 0,04593261 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02300449 0,04589453 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02300449 0,0458565 ! localization within membrane GO:0051668 20 10 0,000 0,02300449 0,04581854 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02527604 0,05030121 ! respiratory burst GO:0045730 17 11 0,000 0,02527604 0,05025964 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02527604 0,05021813 ! neuron fate specification GO:0048665 17 11 0,000 0,02527604 0,0501767 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02527604 0,05013533 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02527604 0,05009404 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02527604 0,05005281 ! thyroid gland development GO:0030878 26 11 0,000 0,02527604 0,05001164 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02527604 0,04997055 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02527604 0,04992952 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02527604 0,04988856 ! response to pain GO:0048265 24 11 0,000 0,02527604 0,04984767 ! T cell proliferation GO:0042098 26 11 0,000 0,02527604 0,04980685 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02527604 0,04976609 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02527604 0,0497254 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02527604 0,04968477 ! bone resorption GO:0045453 16 11 0,000 0,02527604 0,04964421 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02527604 0,04960372 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02527604 0,04956329 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02527604 0,04952293 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02527604 0,04948264 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02527604 0,04944241 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02527604 0,04940224 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02527604 0,04936214 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02527604 0,04932211 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02527604 0,04928214 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02527604 0,04924223 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02527604 0,04920239 ! UV protection GO:0009650 19 11 0,000 0,02527604 0,04916262 ! adult heart development GO:0007512 14 11 0,000 0,02527604 0,04912291 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02527604 0,04908326 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02527604 0,04904368 ! temperature homeostasis GO:0001659 17 11 0,000 0,02527604 0,04900416 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02527604 0,0489647 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02527604 0,04892531 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02527604 0,04888598 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02527604 0,04884671 ! regulation of organ growth GO:0046620 13 11 0,000 0,02527604 0,04880751 ! pigment granule localization GO:0051875 20 11 0,000 0,02527604 0,04876837 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02527604 0,04872929 ! vasoconstriction GO:0042310 18 11 0,000 0,02527604 0,04869028 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02527604 0,04865133 ! embryonic axis specification GO:0000578 18 11 0,000 0,02527604 0,04861244 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02527604 0,04857361 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02527604 0,04853484 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02527604 0,04849614 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02527604 0,0484575 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02527604 0,04841892 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02527604 0,0483804 ! zymogen activation GO:0031638 15 11 0,000 0,02527604 0,04834194 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02527604 0,04830354 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02527604 0,04826521 ! nucleosome positioning GO:0016584 15 11 0,000 0,02527604 0,04822693 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02527604 0,04818872 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02527604 0,04815056 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02527604 0,04811247 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02527604 0,04807443 ! acid secretion GO:0046717 18 11 0,000 0,02527604 0,04803646 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02527604 0,04799855 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02527604 0,04796069 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02527604 0,0479229 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02527604 0,04788517 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02527604 0,04784749 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02527604 0,04780987 ! cholesterol efflux GO:0033344 19 11 0,000 0,02527604 0,04777232 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02527604 0,04773482 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02527604 0,04769738 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02527604 0,04766 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02527604 0,04762268 ! embryonic gut development GO:0048566 15 11 0,000 0,02527604 0,04758541 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02527604 0,04754821 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02527604 0,04751106 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02527604 0,04747397 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02527604 0,04743694 ! defense response to fungus GO:0050832 13 11 0,000 0,02527604 0,04739997 ! developmental induction GO:0031128 19 11 0,000 0,02527604 0,04736305 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02527604 0,04732619 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02527604 0,04728939 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02527604 0,04725265 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02527604 0,04721596 ! nucleus localization GO:0051647 19 11 0,000 0,02527604 0,04717933 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02527604 0,04714276 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02754239 0,05132997 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02754239 0,05129024 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02754239 0,05125058 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02754239 0,05121097 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02754239 0,05117142 ! virus-host interaction GO:0019048 29 12 0,000 0,02754239 0,05113194 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02754239 0,05109252 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02754239 0,05105315 ! cartilage condensation GO:0001502 20 12 0,000 0,02754239 0,05101385 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02754239 0,05097461 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02754239 0,05093543 ! protein complex disassembly GO:0043241 27 12 0,000 0,02754239 0,05089631 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02754239 0,05085725 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02754239 0,05081825 ! hippocampus development GO:0021766 26 12 0,000 0,02754239 0,05077931 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02754239 0,05074042 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02754239 0,0507016 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02754239 0,05066284 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02754239 0,05062414 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02754239 0,05058549 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02754239 0,05054691 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02754239 0,05050838 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02754239 0,05046991 ! drug transport GO:0015893 16 12 0,000 0,02754239 0,0504315 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02754239 0,05039315 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02754239 0,05035486 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02754239 0,05031662 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02754239 0,05027845 ! focal adhesion formation GO:0048041 35 12 0,000 0,02754239 0,05024033 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02754239 0,05020227 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02754239 0,05016426 ! forebrain cell migration GO:0021885 21 12 0,000 0,02754239 0,05012632 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02754239 0,05008843 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02754239 0,0500506 ! entry into host cell GO:0030260 32 12 0,000 0,02754239 0,05001283 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02754239 0,04997511 ! monoamine transport GO:0015844 18 12 0,000 0,02754239 0,04993745 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02754239 0,04989984 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02754239 0,0498623 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02754239 0,04982481 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02754239 0,04978737 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02754239 0,04975 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02754239 0,04971267 ! protein homotetramerization GO:0051289 21 12 0,000 0,02754239 0,04967541 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02754239 0,0496382 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02754239 0,04960104 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02754239 0,04956394 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02754239 0,0495269 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02754239 0,04948991 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02754239 0,04945298 ! cranial nerve development GO:0021545 20 12 0,000 0,02754239 0,0494161 ! fucose catabolic process GO:0019317 22 12 0,000 0,02754239 0,04937928 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02754239 0,04934251 ! histone acetylation GO:0016573 26 12 0,000 0,02754239 0,0493058 ! histone methylation GO:0016571 26 12 0,000 0,02754239 0,04926914 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02754239 0,04923254 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02754239 0,04919599 ! gland morphogenesis GO:0022612 29 12 0,000 0,02754239 0,04915949 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02754239 0,04912305 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02754239 0,04908666 ! T cell homeostasis GO:0043029 25 12 0,000 0,02754239 0,04905033 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02754239 0,04901405 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02754239 0,04897782 ! spleen development GO:0048536 22 12 0,000 0,02754239 0,04894165 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02754239 0,04890553 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02754239 0,04886946 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02754239 0,04883345 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02754239 0,04879749 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02754239 0,04876158 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02754239 0,04872573 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02754239 0,04868993 ! response to cold GO:0009409 17 12 0,000 0,02754239 0,04865418 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02754239 0,04861848 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02754239 0,04858284 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02980355 0,05253284 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02980355 0,05249438 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02980355 0,05245598 ! peroxisomal transport GO:0043574 24 13 0,000 0,02980355 0,05241764 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02980355 0,05237935 ! lipid localization GO:0010876 28 13 0,000 0,02980355 0,05234112 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02980355 0,05230294 ! organelle fusion GO:0048284 32 13 0,000 0,02980355 0,05226482 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02980355 0,05222675 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02980355 0,05218874 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02980355 0,05215079 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02980355 0,05211288 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02980355 0,05207504 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02980355 0,05203725 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02980355 0,05199951 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02980355 0,05196183 ! methionine metabolic process GO:0006555 27 13 0,000 0,02980355 0,05192421 ! plasma membrane organization GO:0007009 24 13 0,000 0,02980355 0,05188664 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02980355 0,05184912 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02980355 0,05181165 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02980355 0,05177425 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02980355 0,05173689 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02980355 0,05169959 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02980355 0,05166234 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02980355 0,05162515 ! exocrine system development GO:0035272 32 13 0,000 0,02980355 0,05158801 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02980355 0,05155092 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02980355 0,05151389 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02980355 0,05147691 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02980355 0,05143998 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02980355 0,0514031 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02980355 0,05136628 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02980355 0,05132951 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02980355 0,0512928 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02980355 0,05125613 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02980355 0,05121952 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02980355 0,05118296 ! ribosome assembly GO:0042255 17 13 0,000 0,02980355 0,05114645 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02980355 0,05111 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02980355 0,0510736 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02980355 0,05103725 ! chromatin silencing GO:0006342 26 13 0,000 0,02980355 0,05100095 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02980355 0,0509647 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02980355 0,0509285 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02980355 0,05089236 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02980355 0,05085626 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02980355 0,05082022 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02980355 0,05078423 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02980355 0,05074829 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02980355 0,0507124 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02980355 0,05067656 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02980355 0,05064077 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02980355 0,05060503 ! embryonic placenta development GO:0001892 23 13 0,000 0,02980355 0,05056934 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02980355 0,05053371 ! insulin secretion GO:0030073 23 13 0,000 0,02980355 0,05049812 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02980355 0,05046258 ! rRNA transcription GO:0009303 25 14 0,000 0,03205952 0,05424416 ! lactation GO:0007595 26 14 0,000 0,03205952 0,05420604 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03205952 0,05416797 ! tRNA modification GO:0006400 20 14 0,000 0,03205952 0,05412996 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03205952 0,054092 ! water transport GO:0006833 21 14 0,000 0,03205952 0,0540541 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03205952 0,05401624 ! non-recombinational repair GO:0000726 25 14 0,000 0,03205952 0,05397844 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03205952 0,0539407 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03205952 0,053903 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03205952 0,05386536 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03205952 0,05382777 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03205952 0,05379023 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03205952 0,05375275 ! palate development GO:0060021 31 14 0,000 0,03205952 0,05371532 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03205952 0,05367794 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03205952 0,05364061 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03205952 0,05360333 ! arginine metabolic process GO:0006525 17 14 0,000 0,03205952 0,05356611 ! regulation of heart rate GO:0002027 24 14 0,000 0,03205952 0,05352894 ! organic alcohol transport GO:0015850 29 14 0,000 0,03205952 0,05349181 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03205952 0,05345474 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03205952 0,05341773 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03205952 0,05338076 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03205952 0,05334384 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03205952 0,05330698 ! L-amino acid transport GO:0015807 30 14 0,000 0,03205952 0,05327016 ! bone mineralization GO:0030282 17 14 0,000 0,03205952 0,0532334 ! stem cell development GO:0048864 43 14 0,000 0,03205952 0,05319669 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03205952 0,05316002 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03205952 0,05312341 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03205952 0,05308685 ! cerebellum development GO:0021549 21 14 0,000 0,03205952 0,05305034 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03205952 0,05301388 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03205952 0,05297747 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03205952 0,05294111 ! cofactor transport GO:0051181 26 14 0,000 0,03205952 0,0529048 ! NADP metabolic process GO:0006739 24 14 0,000 0,03205952 0,05286854 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03205952 0,05283233 ! intestinal absorption GO:0050892 25 14 0,000 0,03205952 0,05279616 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03205952 0,05276005 ! oxygen transport GO:0015671 21 14 0,000 0,03205952 0,05272399 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03205952 0,05268798 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03205952 0,05265201 ! regulation of axon extension GO:0030516 37 14 0,000 0,03205952 0,0526161 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03205952 0,05258023 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03431032 0,05623339 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03431032 0,05619511 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03431032 0,05615688 ! superoxide anion generation GO:0042554 20 15 0,000 0,03431032 0,05611871 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03431032 0,05608058 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03431032 0,05604251 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03431032 0,05600449 ! copper ion transport GO:0006825 20 15 0,000 0,03431032 0,05596652 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03431032 0,0559286 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03431032 0,05589074 ! sulfate transport GO:0008272 23 15 0,000 0,03431032 0,05585292 ! response to cAMP GO:0051591 22 15 0,000 0,03431032 0,05581516 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03431032 0,05577745 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03431032 0,05573978 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03431032 0,05570217 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03431032 0,05566461 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03431032 0,0556271 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03431032 0,05558964 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03431032 0,05555223 ! pituitary gland development GO:0021983 29 15 0,000 0,03431032 0,05551488 ! vesicle coating GO:0006901 33 15 0,000 0,03431032 0,05547757 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03431032 0,05544031 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03431032 0,0554031 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03431032 0,05536594 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03431032 0,05532883 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03431032 0,05529178 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03431032 0,05525477 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03431032 0,05521781 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03431032 0,0551809 ! histone deacetylation GO:0016575 20 15 0,000 0,03431032 0,05514404 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03431032 0,05510722 ! tissue regeneration GO:0042246 26 15 0,000 0,03431032 0,05507046 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03431032 0,05503375 ! water homeostasis GO:0030104 27 15 0,000 0,03431032 0,05499708 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03431032 0,05496047 ! muscle maintenance GO:0046716 26 15 0,000 0,03431032 0,0549239 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03431032 0,05488738 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03431032 0,05485091 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03431032 0,05481449 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03431032 0,05477812 ! cell killing GO:0001906 29 15 0,000 0,03431032 0,05474179 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03431032 0,05470551 ! detection of bacterium GO:0016045 18 15 0,000 0,03431032 0,05466929 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03431032 0,0546331 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03431032 0,05459697 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03431032 0,05456089 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03431032 0,05452485 ! peptide hormone processing GO:0016486 23 15 0,000 0,03431032 0,05448886 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03655596 0,05801691 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03655596 0,05797866 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03655596 0,05794047 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03655596 0,05790233 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03655596 0,05786423 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03655596 0,05782619 ! bone remodeling GO:0046849 27 16 0,000 0,03655596 0,05778819 ! filopodium assembly GO:0046847 32 16 0,000 0,03655596 0,05775025 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03655596 0,05771236 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03655596 0,05767451 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03655596 0,05763672 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03655596 0,05759897 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03655596 0,05756128 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03655596 0,05752363 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03655596 0,05748603 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03655596 0,05744849 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03655596 0,05741099 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03655596 0,05737354 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03655596 0,05733614 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03655596 0,05729878 ! response to osmotic stress GO:0006970 25 16 0,000 0,03655596 0,05726148 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03655596 0,05722422 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03655596 0,05718702 ! fructose metabolic process GO:0006000 25 16 0,000 0,03655596 0,05714986 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03655596 0,05711275 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03655596 0,05707569 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03655596 0,05703867 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03655596 0,05700171 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03655596 0,05696479 ! axon cargo transport GO:0008088 43 16 0,000 0,03655596 0,05692792 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03655596 0,05689109 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03655596 0,05685432 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,03655596 0,05681759 ! DNA replication initiation GO:0006270 27 16 0,000 0,03655596 0,05678091 ! neuron recognition GO:0008038 35 16 0,000 0,03655596 0,05674428 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03655596 0,05670769 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03655596 0,05667115 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03655596 0,05663466 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03655596 0,05659822 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03655596 0,05656182 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03655596 0,05652547 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03655596 0,05648917 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03655596 0,05645291 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03655596 0,0564167 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03655596 0,05638053 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03655596 0,05634442 ! defense response to virus GO:0051607 37 16 0,000 0,03655596 0,05630834 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03879645 0,05972121 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03879645 0,05968303 ! metencephalon development GO:0022037 30 17 0,000 0,03879645 0,05964489 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03879645 0,05960681 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03879645 0,05956877 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03879645 0,05953078 ! signal complex assembly GO:0007172 41 17 0,000 0,03879645 0,05949284 ! endothelial cell migration GO:0043542 28 17 0,000 0,03879645 0,05945494 ! inositol metabolic process GO:0006020 28 17 0,000 0,03879645 0,0594171 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03879645 0,0593793 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03879645 0,05934155 ! glial cell development GO:0021782 27 17 0,000 0,03879645 0,05930385 ! limbic system development GO:0021761 36 17 0,000 0,03879645 0,0592662 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03879645 0,05922859 ! adult walking behavior GO:0007628 33 17 0,000 0,03879645 0,05919103 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03879645 0,05915352 ! heart looping GO:0001947 30 17 0,000 0,03879645 0,05911606 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03879645 0,05907864 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03879645 0,05904128 ! myoblast differentiation GO:0045445 45 17 0,000 0,03879645 0,05900396 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03879645 0,05896668 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03879645 0,05892946 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03879645 0,05889228 ! glycine metabolic process GO:0006544 28 17 0,000 0,03879645 0,05885514 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,03879645 0,05881806 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03879645 0,05878102 ! NAD metabolic process GO:0019674 29 17 0,000 0,03879645 0,05874403 ! membrane budding GO:0006900 37 17 0,000 0,03879645 0,05870708 ! DNA integration GO:0015074 29 17 0,000 0,03879645 0,05867018 ! regulation of protein binding GO:0043393 33 17 0,000 0,03879645 0,05863333 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03879645 0,05859652 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03879645 0,05855976 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03879645 0,05852305 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03879645 0,05848638 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03879645 0,05844976 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03879645 0,05841318 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03879645 0,05837665 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03879645 0,05834016 ! steroid catabolic process GO:0006706 31 17 0,000 0,03879645 0,05830372 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03879645 0,05826733 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03879645 0,05823098 ! gas transport GO:0015669 25 17 0,000 0,03879645 0,05819468 ! organic cation transport GO:0015695 31 17 0,000 0,03879645 0,05815842 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03879645 0,0581222 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03879645 0,05808604 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03879645 0,05804991 ! microspike assembly GO:0030035 36 17 0,000 0,03879645 0,05801383 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03879645 0,0579778 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04103181 0,06128028 ! neuron maturation GO:0042551 42 18 0,000 0,04103181 0,06124226 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04103181 0,0612043 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04103181 0,06116637 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04103181 0,0611285 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04103181 0,06109067 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04103181 0,06105289 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04103181 0,06101516 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04103181 0,06097747 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04103181 0,06093983 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04103181 0,06090224 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04103181 0,06086469 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04103181 0,06082719 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04103181 0,06078973 ! response to retinoic acid GO:0032526 26 18 0,000 0,04103181 0,06075232 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04103181 0,06071496 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04103181 0,06067764 ! response to fungus GO:0009620 21 18 0,000 0,04103181 0,06064037 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04103181 0,06060315 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04103181 0,06056597 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04103181 0,06052883 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04103181 0,06049175 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04103181 0,0604547 ! vitamin transport GO:0051180 27 18 0,000 0,04103181 0,0604177 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04103181 0,06038075 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04103181 0,06034384 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04103181 0,06030698 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04103181 0,06027016 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,04103181 0,06023339 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04103181 0,06019666 ! nerve development GO:0021675 28 18 0,000 0,04103181 0,06015998 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04103181 0,06012334 ! protein secretion GO:0009306 39 19 0,000 0,04326204 0,06335269 ! positive regulation of translation GO:0045727 30 19 0,000 0,04326204 0,06331415 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04326204 0,06327566 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04326204 0,06323722 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04326204 0,06319883 ! skin development GO:0043588 36 19 0,000 0,04326204 0,06316048 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04326204 0,06312218 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04326204 0,06308392 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04326204 0,06304571 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04326204 0,06300755 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04326204 0,06296943 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04326204 0,06293136 ! cerebral cortex development GO:0021987 36 19 0,000 0,04326204 0,06289333 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04326204 0,06285535 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04326204 0,06281742 ! heme metabolic process GO:0042168 36 19 0,000 0,04326204 0,06277953 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04326204 0,06274169 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04326204 0,0627039 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04326204 0,06266615 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04326204 0,06262844 ! peptide cross-linking GO:0018149 37 19 0,000 0,04326204 0,06259078 ! protein export from nucleus GO:0006611 36 19 0,000 0,04326204 0,06255317 ! heart process GO:0003015 30 19 0,000 0,04326204 0,0625156 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04326204 0,06247807 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04326204 0,06244059 ! G1 phase GO:0051318 40 19 0,000 0,04326204 0,06240316 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04326204 0,06236577 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04326204 0,06232842 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04326204 0,06229112 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04326204 0,06225387 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04326204 0,06221666 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04326204 0,06217949 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04326204 0,06214237 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04326204 0,06210529 ! cilium assembly GO:0042384 37 19 0,000 0,04326204 0,06206826 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04326204 0,06203127 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04548716 0,06518291 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04548716 0,06514411 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04548716 0,06510536 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04548716 0,06506665 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04548716 0,06502799 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04548716 0,06498937 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,04548716 0,0649508 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04548716 0,06491228 ! response to vitamin GO:0033273 31 20 0,000 0,04548716 0,0648738 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04548716 0,06483537 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04548716 0,06479698 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04548716 0,06475864 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04548716 0,06472035 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04548716 0,0646821 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04548716 0,06464389 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04548716 0,06460573 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04548716 0,06456761 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04548716 0,06452954 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,04548716 0,06449152 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04548716 0,06445354 ! body fluid secretion GO:0007589 31 20 0,000 0,04548716 0,0644156 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04548716 0,06437771 ! peptide secretion GO:0002790 35 20 0,000 0,04548716 0,06433986 ! stem cell differentiation GO:0048863 53 20 0,000 0,04548716 0,06430206 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04548716 0,0642643 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04548716 0,06422659 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04548716 0,06418892 ! sensory perception of pain GO:0019233 30 20 0,000 0,04548716 0,06415129 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04548716 0,06411371 ! diencephalon development GO:0021536 34 20 0,000 0,04548716 0,06407617 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04548716 0,06403868 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04548716 0,06400123 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04548716 0,06396383 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04548716 0,06392646 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04548716 0,06388915 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04548716 0,06385187 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04548716 0,06381464 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04548716 0,06377745 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04548716 0,06374031 ! regulation of glucose import GO:0046324 29 20 0,000 0,04548716 0,06370321 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04548716 0,06366615 ! actin filament-based movement GO:0030048 43 20 0,000 0,04548716 0,06362913 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04548716 0,06359216 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04548716 0,06355523 ! negative regulation of translation GO:0017148 29 20 0,000 0,04548716 0,06351834 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04548716 0,0634815 ! regulation of cell killing GO:0031341 42 21 0,000 0,04770718 0,06654114 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04770718 0,06650259 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04770718 0,06646408 ! hormone secretion GO:0046879 38 21 0,000 0,04770718 0,06642562 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04770718 0,0663872 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04770718 0,06634883 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04770718 0,0663105 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04770718 0,06627221 ! axis specification GO:0009798 38 21 0,000 0,04770718 0,06623397 ! ovarian follicle development GO:0001541 35 21 0,000 0,04770718 0,06619577 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04770718 0,06615762 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04770718 0,06611951 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04770718 0,06608145 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04770718 0,06604342 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04770718 0,06600545 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04770718 0,06596751 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04770718 0,06592962 ! vasodilation GO:0042311 39 21 0,000 0,04770718 0,06589177 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04770718 0,06585397 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04770718 0,06581621 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04770718 0,06577849 ! DNA modification GO:0006304 34 21 0,000 0,04770718 0,06574082 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04770718 0,06570319 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04770718 0,0656656 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04770718 0,06562806 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04770718 0,06559055 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04770718 0,0655531 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04770718 0,06551568 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04770718 0,06547831 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04770718 0,06544098 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04770718 0,06540369 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04770718 0,06536644 ! collagen catabolic process GO:0030574 28 21 0,000 0,04770718 0,06532924 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04770718 0,06529208 ! gut development GO:0048565 39 21 0,000 0,04770718 0,06525496 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04992211 0,06824579 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04992211 0,06820704 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04992211 0,06816833 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04992211 0,06812966 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04992211 0,06809104 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04992211 0,06805246 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04992211 0,06801392 ! regeneration GO:0031099 41 22 0,000 0,04992211 0,06797543 ! keratinization GO:0031424 28 22 0,000 0,04992211 0,06793699 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04992211 0,06789858 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04992211 0,06786022 ! sensory perception of taste GO:0050909 28 22 0,000 0,04992211 0,0678219 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04992211 0,06778363 ! vacuolar transport GO:0007034 36 22 0,000 0,04992211 0,0677454 ! lysosome organization GO:0007040 41 22 0,000 0,04992211 0,06770721 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04992211 0,06766906 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04992211 0,06763096 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04992211 0,0675929 ! fucose metabolic process GO:0006004 39 22 0,000 0,04992211 0,06755489 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04992211 0,06751691 ! ureteric bud development GO:0001657 43 22 0,000 0,04992211 0,06747898 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04992211 0,06744109 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04992211 0,06740325 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04992211 0,06736545 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,04992211 0,06732768 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04992211 0,06728997 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04992211 0,06725229 ! sarcomere organization GO:0045214 30 22 0,000 0,04992211 0,06721466 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04992211 0,06717706 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04992211 0,06713951 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04992211 0,06710201 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04992211 0,06706454 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,04992211 0,06702711 ! protein stabilization GO:0050821 39 22 0,000 0,04992211 0,06698973 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05213196 0,0699161 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05213196 0,06987715 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05213196 0,06983825 ! gluconeogenesis GO:0006094 33 23 0,000 0,05213196 0,06979938 ! viral genome replication GO:0019079 41 23 0,000 0,05213196 0,06976056 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05213196 0,06972178 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05213196 0,06968305 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05213196 0,06964436 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05213196 0,06960571 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05213196 0,0695671 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05213196 0,06952854 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,05213196 0,06949002 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05213196 0,06945154 ! peroxisome organization GO:0007031 37 23 0,000 0,05213196 0,06941311 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05213196 0,06937472 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05213196 0,06933637 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05213196 0,06929806 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05213196 0,0692598 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,05213196 0,06922157 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05213196 0,06918339 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05213196 0,06914525 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05213196 0,06910716 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05213196 0,0690691 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05213196 0,06903109 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05213196 0,06899312 ! fatty acid transport GO:0015908 44 23 0,000 0,05213196 0,06895519 ! platelet activation GO:0030168 37 23 0,000 0,05213196 0,0689173 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05213196 0,06887946 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05213196 0,06884165 ! hormone transport GO:0009914 40 23 0,000 0,05213196 0,06880389 ! cell-cell recognition GO:0009988 25 23 0,000 0,05213196 0,06876617 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05213196 0,06872849 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05213196 0,06869085 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05213196 0,06865325 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05213196 0,06861569 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05433674 0,07147851 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05433674 0,07143945 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05433674 0,07140044 ! vesicle docking GO:0048278 47 24 0,000 0,05433674 0,07136146 ! spinal cord development GO:0021510 47 24 0,000 0,05433674 0,07132253 ! vacuole organization GO:0007033 43 24 0,000 0,05433674 0,07128364 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05433674 0,0712448 ! digestive system process GO:0022600 39 24 0,000 0,05433674 0,07120599 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05433674 0,07116723 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05433674 0,07112851 ! regulation of behavior GO:0050795 43 24 0,000 0,05433674 0,07108983 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05433674 0,0710512 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05433674 0,0710126 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05433674 0,07097405 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05433674 0,07093554 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05433674 0,07089707 ! pallium development GO:0021543 49 24 0,000 0,05433674 0,07085864 ! pentose metabolic process GO:0019321 35 24 0,000 0,05433674 0,07082026 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,05433674 0,07078192 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05433674 0,07074361 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05433674 0,07070535 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05433674 0,07066714 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05433674 0,07062896 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05433674 0,07059082 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05433674 0,07055273 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05433674 0,07051467 ! regulation of amine transport GO:0051952 40 24 0,000 0,05433674 0,07047666 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05653647 0,07329027 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05653647 0,07325081 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05653647 0,07321138 ! phototransduction GO:0007602 33 25 0,000 0,05653647 0,073172 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05653647 0,07313266 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05653647 0,07309336 ! sperm motility GO:0030317 31 25 0,000 0,05653647 0,07305411 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05653647 0,07301489 ! receptor metabolic process GO:0043112 46 25 0,000 0,05653647 0,07297572 ! chromosome condensation GO:0030261 45 25 0,000 0,05653647 0,07293659 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05653647 0,07289751 ! neural crest cell development GO:0014032 54 25 0,000 0,05653647 0,07285846 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05653647 0,07281946 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05653647 0,0727805 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05653647 0,07274158 ! interaction with host GO:0051701 62 25 0,000 0,05653647 0,0727027 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05653647 0,07266386 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05653647 0,07262506 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05653647 0,07258631 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,05653647 0,0725476 ! immunoglobulin production GO:0002377 55 25 0,000 0,05653647 0,07250893 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05653647 0,0724703 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05653647 0,07243171 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05653647 0,07239316 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05653647 0,07235465 ! telomere organization GO:0032200 43 25 0,000 0,05653647 0,07231619 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05653647 0,07227776 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05653647 0,07223938 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05873115 0,0750038 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05873115 0,07496401 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05873115 0,07492426 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05873115 0,07488456 ! initiation of viral infection GO:0019059 57 26 0,000 0,05873115 0,07484489 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05873115 0,07480527 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05873115 0,07476569 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05873115 0,07472615 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05873115 0,07468666 ! molting cycle process GO:0022404 50 26 0,000 0,05873115 0,0746472 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05873115 0,07460779 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05873115 0,07456842 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,05873115 0,07452909 ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,05873115 0,0744898 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,05873115 0,07445056 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05873115 0,07441135 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05873115 0,07437219 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05873115 0,07433307 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05873115 0,07429398 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05873115 0,07425494 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05873115 0,07421594 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05873115 0,07417699 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05873115 0,07413807 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05873115 0,07409919 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05873115 0,07406036 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05873115 0,07402156 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05873115 0,0739828 ! neuron fate commitment GO:0048663 48 27 0,000 0,06092081 0,07670092 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06092081 0,07666081 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06092081 0,07662073 ! iron ion transport GO:0006826 59 27 0,000 0,06092081 0,0765807 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,06092081 0,07654071 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06092081 0,07650076 ! protein amino acid acylation GO:0043543 55 27 0,000 0,06092081 0,07646086 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06092081 0,07642099 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06092081 0,07638117 ! fat cell differentiation GO:0045444 50 27 0,000 0,06092081 0,07634139 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06092081 0,07630165 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06092081 0,07626195 ! autophagy GO:0006914 41 27 0,000 0,06092081 0,07622229 ! male gonad development GO:0008584 44 27 0,000 0,06092081 0,07618267 ! response to toxin GO:0009636 47 27 0,000 0,06092081 0,0761431 ! primary neural tube formation GO:0014020 51 27 0,000 0,06092081 0,07610356 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06092081 0,07606407 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06092081 0,07602462 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06092081 0,0759852 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06092081 0,07594583 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06092081 0,0759065 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06092081 0,07586722 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06310544 0,07854717 ! circadian rhythm GO:0007623 50 28 0,000 0,06310544 0,07850656 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06310544 0,07846599 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06310544 0,07842546 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06310544 0,07838497 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06310544 0,07834452 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06310544 0,07830412 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06310544 0,07826375 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06310544 0,07822343 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06310544 0,07818315 ! synaptogenesis GO:0007416 42 28 0,000 0,06310544 0,07814291 ! lipid oxidation GO:0034440 43 28 0,000 0,06310544 0,07810272 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06310544 0,07806256 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06310544 0,07802245 ! translational initiation GO:0006413 65 29 0,000 0,06528506 0,08067583 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06528506 0,08063442 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06528506 0,08059305 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06528506 0,08055172 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06528506 0,08051043 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06528506 0,08046919 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06528506 0,08042798 ! cell fate determination GO:0001709 60 29 0,000 0,06528506 0,08038682 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06528506 0,0803457 ! detection of light stimulus GO:0009583 38 29 0,000 0,06528506 0,08030463 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,06528506 0,08026359 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06528506 0,0802226 ! regulation of coagulation GO:0050818 46 29 0,000 0,06528506 0,08018165 ! zinc ion transport GO:0006829 45 30 0,000 0,06745968 0,0828102 ! membrane docking GO:0022406 61 30 0,000 0,06745968 0,08276797 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06745968 0,08272579 ! cell junction assembly GO:0034329 78 30 0,000 0,06745968 0,08268364 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06745968 0,08264154 ! acute-phase response GO:0006953 49 30 0,000 0,06745968 0,08259949 ! myofibril assembly GO:0030239 47 30 0,000 0,06745968 0,08255747 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,06745968 0,0825155 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06745968 0,08247357 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06745968 0,08243169 ! phospholipid transport GO:0015914 51 30 0,000 0,06745968 0,08238984 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06745968 0,08234804 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06745968 0,08230628 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06745968 0,08226457 ! eye morphogenesis GO:0048592 60 30 0,000 0,06745968 0,08222289 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06745968 0,08218126 ! response to heat GO:0009408 50 30 0,000 0,06745968 0,08213967 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06962932 0,08473856 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06962932 0,08469572 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06962932 0,08465292 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06962932 0,08461017 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06962932 0,08456746 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06962932 0,08452479 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06962932 0,08448217 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06962932 0,08443958 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06962932 0,08439705 ! ovulation cycle process GO:0022602 49 31 0,000 0,06962932 0,08435455 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06962932 0,0843121 ! peptide transport GO:0015833 55 31 0,000 0,06962932 0,08426969 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06962932 0,08422732 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06962932 0,08418499 ! mesoderm formation GO:0001707 69 31 0,000 0,06962932 0,08414271 ! natural killer cell activation GO:0030101 45 31 0,000 0,06962932 0,08410047 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06962932 0,08405827 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06962932 0,08401612 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06962932 0,083974 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06962932 0,08393193 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06962932 0,0838899 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07179398 0,08645461 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07179398 0,08641136 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07179398 0,08636815 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07179398 0,08632499 ! cholesterol transport GO:0030301 56 32 0,000 0,07179398 0,08628187 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07179398 0,0862388 ! spliceosome assembly GO:0000245 67 32 0,000 0,07179398 0,08619576 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07179398 0,08615277 ! metanephros development GO:0001656 74 32 0,000 0,07179398 0,08610982 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07179398 0,08606692 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07179398 0,08602406 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,07179398 0,08598124 ! muscle cell development GO:0055001 49 32 0,000 0,07179398 0,08593846 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07179398 0,08589573 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07179398 0,08585304 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07179398 0,08581039 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07179398 0,08576778 ! ovulation cycle GO:0042698 51 32 0,000 0,07179398 0,08572521 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07179398 0,08568269 ! hindbrain development GO:0030902 61 32 0,000 0,07179398 0,08564021 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07179398 0,08559777 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07179398 0,08555538 ! gene silencing GO:0016458 65 32 0,000 0,07179398 0,08551302 ! post-embryonic development GO:0009791 69 33 0,000 0,07395367 0,08804183 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07395367 0,08799829 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,07395367 0,08795479 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07395367 0,08791133 ! formation of primary germ layer GO:0001704 72 33 0,000 0,07395367 0,08786792 ! cell fate specification GO:0001708 52 33 0,000 0,07395367 0,08782455 ! sterol transport GO:0015918 57 33 0,000 0,07395367 0,08778122 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,07395367 0,08773794 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07395367 0,08769469 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07395367 0,08765149 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07395367 0,08760834 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07610841 0,09011656 ! glial cell differentiation GO:0010001 63 34 0,000 0,07610841 0,09007223 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07610841 0,09002795 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07610841 0,08998371 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07610841 0,08993951 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07610841 0,08989536 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07610841 0,08985125 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07610841 0,08980718 ! mismatch repair GO:0006298 46 34 0,000 0,07610841 0,08976316 ! spermatid development GO:0007286 63 34 0,000 0,07610841 0,08971918 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07610841 0,08967524 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07610841 0,08963135 ! placenta development GO:0001890 53 34 0,000 0,07610841 0,0895875 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,07610841 0,08954369 ! regulation of muscle development GO:0048634 70 35 0,000 0,07825821 0,09202799 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07825821 0,09198303 ! negative regulation of secretion GO:0051048 63 35 0,000 0,07825821 0,09193811 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07825821 0,09189324 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07825821 0,09184842 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,07825821 0,09180364 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,07825821 0,0917589 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,07825821 0,0917142 ! cytokine production GO:0001816 59 35 0,000 0,07825821 0,09166955 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,07825821 0,09162494 ! neural tube formation GO:0001841 67 35 0,000 0,07825821 0,09158038 ! vesicle localization GO:0051648 64 35 0,000 0,07825821 0,09153586 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,08040308 0,09399894 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08040308 0,09395328 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08040308 0,09390767 ! cell junction organization GO:0034330 86 36 0,000 0,08040308 0,09386211 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08040308 0,09381659 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,08040308 0,09377112 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08040308 0,09372568 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08040308 0,0936803 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08040308 0,09363495 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,08040308 0,09358965 ! aerobic respiration GO:0009060 55 36 0,000 0,08040308 0,0935444 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,08040308 0,09349918 ! embryonic organ development GO:0048568 57 36 0,000 0,08040308 0,09345401 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08040308 0,09340889 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08254303 0,09584871 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08254303 0,09580247 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,08254303 0,09575628 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08254303 0,09571013 ! organic anion transport GO:0015711 68 37 0,000 0,08254303 0,09566403 ! tissue remodeling GO:0048771 76 37 0,000 0,08254303 0,09561797 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08254303 0,09557196 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08254303 0,09552599 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,08254303 0,09548006 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08254303 0,09543418 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,08254303 0,09538834 ! glycogen metabolic process GO:0005977 61 37 0,000 0,08254303 0,09534255 ! pigment metabolic process GO:0042440 80 37 0,000 0,08254303 0,0952968 ! spermatid differentiation GO:0048515 66 37 0,000 0,08254303 0,09525109 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,08254303 0,09520543 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,08467807 0,09762119 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,08467807 0,09757444 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,08467807 0,09752773 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,08467807 0,09748107 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,08467807 0,09743445 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,08467807 0,09738787 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,08467807 0,09734134 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,08467807 0,09729486 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,08467807 0,09724842 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,08467807 0,09720202 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,08467807 0,09715567 ! glucan metabolic process GO:0044042 62 38 0,000 0,08467807 0,09710936 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,08680821 0,09950479 ! organic ether metabolic process GO:0018904 55 39 0,000 0,08680821 0,09945741 ! segmentation GO:0035282 67 39 0,000 0,08680821 0,09941007 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08680821 0,09936277 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08680821 0,09931553 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08680821 0,09926832 ! RNA modification GO:0009451 57 39 0,000 0,08680821 0,09922116 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08680821 0,09917405 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08893346 0,10155383 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08893346 0,10150565 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08893346 0,10145752 ! negative regulation of binding GO:0051100 72 40 0,000 0,08893346 0,10140944 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08893346 0,1013614 ! mesenchymal cell development GO:0014031 87 40 0,000 0,08893346 0,10131341 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08893346 0,10126546 ! maintenance of protein location GO:0045185 91 40 0,000 0,08893346 0,10121756 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09105384 0,10358182 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,09105384 0,10353287 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09105384 0,10348396 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09105384 0,1034351 ! gliogenesis GO:0042063 88 41 0,000 0,09105384 0,10338629 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,09105384 0,10333752 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,09105384 0,1032888 ! polyol metabolic process GO:0019751 66 41 0,000 0,09105384 0,10324013 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,09105384 0,1031915 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,09316936 0,1055393 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,09316936 0,10548964 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,09316936 0,10544002 ! regulation of tube size GO:0035150 71 42 0,000 0,09316936 0,10539045 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,09316936 0,10534092 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,09316936 0,10529144 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,09316936 0,10524201 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,09316936 0,10519262 ! neuron migration GO:0001764 79 42 0,000 0,09316936 0,10514328 ! regulation of protein secretion GO:0050708 71 42 0,000 0,09316936 0,10509399 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,09528002 0,10742443 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09528002 0,10737411 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09528002 0,10732384 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09528002 0,10727362 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,09528002 0,10722345 ! glucose transport GO:0015758 65 43 0,000 0,09528002 0,10717332 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09528002 0,10712324 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09528002 0,1070732 ! neural tube development GO:0021915 77 43 0,000 0,09528002 0,10702322 ! striated muscle contraction GO:0006941 77 43 0,000 0,09528002 0,10697328 ! phagocytosis GO:0006909 90 43 0,000 0,09528002 0,10692338 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09528002 0,10687353 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09738584 0,10918468 ! hexose transport GO:0008645 67 44 0,000 0,09738584 0,10913383 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09738584 0,10908302 ! biopolymer methylation GO:0043414 84 44 0,000 0,09738584 0,10903226 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09738584 0,10898155 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09738584 0,10893088 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09738584 0,10888027 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09948683 0,11117757 ! glycolysis GO:0006096 65 45 0,000 0,09948683 0,11112595 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09948683 0,11107439 ! leukocyte migration GO:0050900 68 45 0,000 0,09948683 0,11102287 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,09948683 0,1109714 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09948683 0,11091998 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09948683 0,1108686 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09948683 0,11081727 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09948683 0,11076599 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09948683 0,11071476 ! cell growth GO:0016049 84 45 0,000 0,09948683 0,11066357 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,10158299 0,11294301 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,10158299 0,11289085 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,10158299 0,11283873 ! response to insulin stimulus GO:0032868 95 46 0,000 0,10158299 0,11278666 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,10158299 0,11273463 ! positive regulation of defense response GO:0031349 76 47 0,000 0,10367435 0,11500253 ! response to calcium ion GO:0051592 81 47 0,000 0,10367435 0,11494953 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,10367435 0,11489659 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,10367435 0,11484369 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,10367435 0,11479084 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,10367435 0,11473803 ! JNK cascade GO:0007254 91 47 0,000 0,10367435 0,11468528 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,10367435 0,11463258 ! methylation GO:0032259 90 47 0,000 0,10367435 0,11457992 ! protein homooligomerization GO:0051260 76 47 0,000 0,10367435 0,11452731 ! Notch signaling pathway GO:0007219 96 48 0,000 0,10576091 0,11677868 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10576091 0,11672511 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,10576091 0,11667159 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,10576091 0,11661812 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10576091 0,1165647 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10576091 0,11651133 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10784268 0,11875034 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10784268 0,11869601 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10784268 0,11864174 ! regulation of ion transport GO:0043269 77 49 0,000 0,10784268 0,11858752 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10784268 0,11853334 ! peptide metabolic process GO:0006518 76 49 0,000 0,10784268 0,11847922 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10784268 0,11842514 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10784268 0,11837111 ! endocrine system development GO:0035270 104 49 0,000 0,10784268 0,11831714 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10784268 0,11826321 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,10991967 0,12048598 ! regulation of ossification GO:0030278 117 50 0,000 0,10991967 0,12043111 ! inner ear development GO:0048839 79 50 0,000 0,10991967 0,1203763 ! histone modification GO:0016570 91 50 0,000 0,10991967 0,12032153 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10991967 0,12026682 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10991967 0,12021215 ! positive regulation of binding GO:0051099 78 51 0,000 0,1119919 0,12242276 ! viral infectious cycle GO:0019058 99 51 0,000 0,1119919 0,12236717 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1119919 0,12231162 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,1119919 0,12225613 ! excretion GO:0007588 83 51 0,000 0,1119919 0,12220068 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1119919 0,12214529 ! chromatin remodeling GO:0006338 109 51 0,000 0,1119919 0,12208994 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1119919 0,12203465 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,1119919 0,1219794 ! vesicle organization GO:0016050 107 51 0,000 0,1119919 0,12192421 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,1119919 0,12186907 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,11405937 0,12406277 ! membrane fusion GO:0006944 110 52 0,000 0,11405937 0,1240067 ! positive regulation of growth GO:0045927 90 52 0,000 0,11405937 0,12395069 ! covalent chromatin modification GO:0016569 101 52 0,000 0,11405937 0,12389473 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,11405937 0,12383883 ! amino acid activation GO:0043038 92 52 0,000 0,11405937 0,12378297 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,11405937 0,12372716 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,11612209 0,12590796 ! RNA catabolic process GO:0006401 93 53 0,000 0,11612209 0,12585124 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11612209 0,12579458 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11612209 0,12573796 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,11612209 0,1256814 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11612209 0,12562489 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,11612209 0,12556843 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,11818008 0,12773643 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11818008 0,12767907 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11818008 0,12762176 ! cell recognition GO:0008037 85 54 0,000 0,11818008 0,12756451 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11818008 0,1275073 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11818008 0,12745015 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11818008 0,12739305 ! chloride transport GO:0006821 90 55 0,000 0,12023335 0,12954834 ! glucose catabolic process GO:0006007 82 55 0,000 0,12023335 0,12949035 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,12023335 0,12943241 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,12023335 0,12937453 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,12023335 0,12931669 ! gastrulation GO:0007369 112 55 0,000 0,12023335 0,12925891 ! heart morphogenesis GO:0003007 97 55 0,000 0,12023335 0,12920118 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,12023335 0,1291435 ! RNA elongation GO:0006354 79 55 0,000 0,12023335 0,12908587 ! regulation of actin filament length GO:0030832 105 56 0,000 0,12228191 0,1312267 ! sensory perception of smell GO:0007608 80 56 0,000 0,12228191 0,1311682 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,12228191 0,13110975 ! proton transport GO:0015992 94 56 0,000 0,12228191 0,13105134 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,12432576 0,13318245 ! lipid modification GO:0030258 97 57 0,000 0,12432576 0,13312318 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,12432576 0,13306396 ! maintenance of location GO:0051235 118 57 0,000 0,12432576 0,13300479 ! hydrogen transport GO:0006818 97 58 0,000 0,12636492 0,13512622 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,12636492 0,13506619 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12636492 0,13500622 ! adult behavior GO:0030534 99 58 0,000 0,12636492 0,13494629 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,12636492 0,13488643 ! positive regulation of secretion GO:0051047 95 59 0,000 0,1283994 0,13699732 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1283994 0,1369366 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1283994 0,13687593 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,1283994 0,13681531 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,13042921 0,13891664 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,13042921 0,13885517 ! regulation of heart contraction GO:0008016 110 60 0,000 0,13042921 0,13879376 ! camera-type eye development GO:0043010 116 60 0,000 0,13042921 0,1387324 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,13042921 0,13867109 ! kidney development GO:0001822 122 60 0,000 0,13042921 0,13860984 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,13245436 0,14069987 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,13245436 0,14063778 ! mesoderm development GO:0007498 119 61 0,000 0,13245436 0,14057574 ! tRNA processing GO:0008033 89 61 0,000 0,13245436 0,14051376 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,13245436 0,14045183 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,13245436 0,14038996 ! viral reproductive process GO:0022415 126 62 0,000 0,13447487 0,14246875 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,13447487 0,14240604 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,13649073 0,14447721 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,13649073 0,14441367 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13649073 0,14435019 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,13649073 0,14428677 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13850196 0,14634858 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13850196 0,14628434 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13850196 0,14622015 GO:0048609|reproductive process in a multicellular organism, ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,14050858 0,14827353 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,14050858 0,14820852 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,14050858 0,14814358 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,14050858 0,14807869 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,14251059 0,1501228 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,14251059 0,1500571 ! secondary metabolic process GO:0019748 116 66 0,000 0,14251059 0,14999146 ! cell projection assembly GO:0030031 120 66 0,000 0,14251059 0,14992588 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,144508 0,15196078 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,144508 0,15189439 ! activation of MAPK activity GO:0000187 115 67 0,000 0,144508 0,15182806 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,144508 0,15176179 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,144508 0,15169557 ! hexose catabolic process GO:0019320 104 67 0,000 0,144508 0,15162942 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,144508 0,15156332 ! amino acid transport GO:0006865 125 68 0,000 0,14650083 0,15358649 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14650083 0,1535196 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14650083 0,15345276 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,14650083 0,15338599 ! viral reproduction GO:0016032 134 68 0,000 0,14650083 0,15331927 ! regulation of lipase activity GO:0060191 130 68 0,000 0,14650083 0,15325261 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14650083 0,153186 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14848908 0,15519754 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14848908 0,15513015 ! urogenital system development GO:0001655 137 69 0,000 0,14848908 0,15506282 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14848908 0,15499554 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14848908 0,15492833 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14848908 0,15486117 ! appendage morphogenesis GO:0035107 135 70 0,000 0,15047277 0,15686199 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,15245189 0,15885633 ! appendage development GO:0048736 136 71 0,000 0,15245189 0,15878756 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,15245189 0,15871885 ! regulation of immune effector process GO:0002697 137 71 0,000 0,15245189 0,1586502 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,15442648 0,16063559 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,15442648 0,16056617 ! carbohydrate transport GO:0008643 110 72 0,000 0,15442648 0,16049681 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,15442648 0,16042751 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,15442648 0,16035827 ! regulation of blood pressure GO:0008217 125 73 0,000 0,15639653 0,16233393 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15639653 0,16226393 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,15836205 0,16423237 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,15836205 0,16416161 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15836205 0,16409091 ! exocytosis GO:0006887 133 74 0,000 0,15836205 0,16402028 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15836205 0,1639497 ! eye development GO:0001654 143 74 0,000 0,15836205 0,16387918 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,16032307 0,16583719 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,16032307 0,16576592 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,16032307 0,16569471 ! rhythmic process GO:0048511 128 75 0,000 0,16032307 0,16562357 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,16227957 0,16757281 ! defense response to bacterium GO:0042742 89 76 0,000 0,16227957 0,16750092 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,16227957 0,1674291 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,16227957 0,16735733 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,16423159 0,16929786 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,16423159 0,16922535 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,16423159 0,16915291 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,16423159 0,16908053 ! blood coagulation GO:0007596 146 78 0,000 0,16617912 0,17101238 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,16617912 0,17093927 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,16812217 0,17286408 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,16812217 0,17279024 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,16812217 0,17271646 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,17006076 0,17463346 ! response to metal ion GO:0010038 140 80 0,000 0,17006076 0,17455896 ! muscle cell differentiation GO:0042692 159 80 0,000 0,17006076 0,17448452 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,17006076 0,17441014 ! inorganic anion transport GO:0015698 138 80 0,000 0,17006076 0,17433583 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,1719949 0,1762435 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,1719949 0,17616847 ! digestion GO:0007586 112 81 0,000 0,1719949 0,17609351 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,1719949 0,1760186 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,1719949 0,17594377 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,1719949 0,17586899 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,1739246 0,1777666 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,1739246 0,17769112 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,1739246 0,1776157 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,1739246 0,17754034 ! response to oxygen levels GO:0070482 176 83 0,000 0,17584986 0,1794295 ! regulation of lyase activity GO:0051339 160 83 0,000 0,17584986 0,17935344 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,1777707 0,18123573 ! hemostasis GO:0007599 158 84 0,000 0,1777707 0,18115896 ! regulation of ligase activity GO:0051340 142 84 0,000 0,1777707 0,18108227 ! response to unfolded protein GO:0006986 131 85 0,000 0,17968713 0,18295693 ! nucleosome assembly GO:0006334 122 85 0,000 0,17968713 0,18287954 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17968713 0,18280221 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,17968713 0,18272495 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,18159915 0,18459128 ! response to inorganic substance GO:0010035 153 86 0,000 0,18159915 0,18451333 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,18159915 0,18443544 ! chromatin assembly GO:0031497 124 86 0,000 0,18159915 0,18435762 ! tube morphogenesis GO:0035239 176 86 0,000 0,18159915 0,18427987 ! alcohol catabolic process GO:0046164 130 86 0,000 0,18159915 0,18420218 ! amine transport GO:0015837 155 86 0,000 0,18159915 0,18412455 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,18350678 0,18598034 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,18350678 0,18590203 ! cellular respiration GO:0045333 135 88 0,000 0,18541003 0,18775107 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,18541003 0,18767208 ! regulation of DNA binding GO:0051101 155 88 0,000 0,18541003 0,18759316 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,18541003 0,18751431 ! cellular defense response GO:0006968 114 89 0,000 0,18730891 0,18935514 ! ossification GO:0001503 188 90 0,000 0,18920342 0,19119001 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,18920342 0,19110975 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,18920342 0,19102955 ! bone development GO:0060348 189 91 0,000 0,19109358 0,19285702 ! sterol metabolic process GO:0016125 152 91 0,000 0,19109358 0,19277616 ! response to protein stimulus GO:0051789 149 91 0,000 0,19109358 0,19269537 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,19109358 0,19261464 ! regulation of defense response GO:0031347 149 92 0,000 0,19297939 0,19443401 ! nucleosome organization GO:0034728 138 92 0,000 0,19297939 0,19435262 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,19297939 0,1942713 ! vitamin metabolic process GO:0006766 139 92 0,000 0,19297939 0,19419005 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,19486087 0,19600136 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,19486087 0,19591945 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,19486087 0,19583762 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,19486087 0,19575585 ! female pregnancy GO:0007565 164 94 0,000 0,19673803 0,19755914 ! forebrain development GO:0030900 188 95 0,000 0,19861087 0,19935659 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,19861087 0,19927346 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,20047941 0,20106438 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,20047941 0,2009806 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,20234365 0,20276502 ! hormone metabolic process GO:0042445 157 97 0,000 0,20234365 0,20268061 ! response to virus GO:0009615 160 98 0,000 0,20420361 0,20445854 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,20420361 0,20437349 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,20420361 0,20428851 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,20605929 0,20605929